title: Tackling infection owing to brain-eating amoeba.
abstract: In view of the devastating nature of primary amoebic meningoencephalitis caused by Naegleria fowleri and the problems associated with diagnostic delays and chemotherapeutic failures, here we propose a noninvasive diagnostic method using the 'reverse transcribrial route device', a novel strategy in the management of this life-threatening infection with a case fatality rate of more than 90%. The proposed rationale should stimulate interest in this emerging infection that almost always proves fatal.
authors.affiliation: Department of Biological and Biomedical Sciences, Aga Khan University, Stadium Road, Karachi, Pakistan.
authors.forename: Abdul Mannan
authors.initials: AM
authors.lastname: Baig
authors.affiliation: Department of Biological and Biomedical Sciences, Aga Khan University, Stadium Road, Karachi, Pakistan. Electronic address: naveed5438@gmail.com.
authors.forename: Naveed Ahmed
authors.initials: NA
authors.lastname: Khan
mesh_terms: D000562:Amebiasis / Q000175:diagnosis* / Q000469:parasitology / Q000628:therapy; D000818:Animals; D057785:Catheters; D020808:Central Nervous System Protozoal Infections / Q000175:diagnosis* / Q000469:parasitology / Q000628:therapy; D004867:Equipment Design; D006801:Humans; D016848:Naegleria fowleri; D009666:Nose / Q000469:parasitology
keywords: Brain-eating amoebae; Diagnosis; Management; Naegleria fowleri; Primary amoebic meningoencephalitis; Treatment