title: Microencapsulation of indocyanine green for potential applications in image-guided drug delivery.
abstract: We present a novel process to encapsulate indocyanine green (ICG) in liposomal droplets at high concentration for potential applications in image-guided drug delivery. The microencapsulation process follows two consecutive steps of droplet formation by liquid-driven coaxial flow focusing (LDCFF) and solvent removal by oil phase dewetting. These biocompatible lipid vesicles may have important applications in drug delivery and fluorescence imaging.
authors.affiliation: Department of Precision Machinery and Precision Instrumentation, University of Science and Technology of China, Hefei, Anhui 230026, PR China.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Zhu
authors.forename: Ting
authors.initials: T
authors.lastname: Si
authors.forename: Ronald X
authors.initials: RX
authors.lastname: Xu
mesh_terms: D004339:Drug Compounding; D016503:Drug Delivery Systems / Q000379:methods*; D007208:Indocyanine Green / Q000032:analysis* / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry; D057054:Molecular Imaging; D010316:Particle Size; D013499:Surface Properties
chemical_list: D008081:Liposomes; D007208:Indocyanine Green