title: Extraction site preservation using an in-situ hardening alloplastic bone graft substitute.
abstract: This case report highlights the use of an in-situ hardening alloplastic bone grafting material composed of beta-tricalcium phosphate (β-TCP) granules coated with poly(lactic-co-glycolic acid) (PLGA) to preserve the dimensions and architecture of the alveolar ridge after atraumatic extraction. This material provided a stable scaffold that, although left uncovered, deterred the ingrowth of unwanted soft tissue, allowing newly formed keratinized soft tissue to proliferate over the healing grafted socket and gradually cover the site. At re-entry after 4 months adequate newly formed bone was observed, allowing for the correct positional placement of an implant. The results of this case suggest that an in-situ hardening alloplastic grafting material can be successfully utilized with minimally invasive procedures to preserve the bone and the soft-tissue profile of the alveolar ridge for future implant rehabilitation.
authors.affiliation: Researcher, Department of Oral and Maxillofacial Surgery, Dental School, University of Athens, Greece, Private Practice, Oral Surgery and Implant Dentistry, Athens, Greece.
authors.forename: Minas D
authors.initials: MD
authors.lastname: Leventis
authors.affiliation: Visiting Professor in Periodontology and Implant Dentistry, School of Dentistry, University of Detroit Mercy, Detroit, Michigan; Private Practice, Implant Dentistry, Kensington, London, UK.
authors.forename: Peter
authors.initials: P
authors.lastname: Fairbairn
authors.affiliation: Departments of Periodontics and Implant Dentistry, Oral Surgery, New York University College of Dentistry, New York, New York; Private Practice, Periodontics and Implant Dentistry, Scarsdale and New York, New York.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Horowitz
mesh_terms: D000368:Aged; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D001672:Biocompatible Materials; D018786:Bone Substitutes / Q000627:therapeutic use*; D002130:Calcium Phosphates; D002951:Citrates / Q000627:therapeutic use*; D019250:Dental Implants, Single-Tooth; D006801:Humans; D007180:Incisor; D019344:Lactic Acid; D008297:Male; D011091:Polyesters / Q000627:therapeutic use*; D011100:Polyglycolic Acid; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D014081:Tooth Extraction; D014082:Tooth Fractures / Q000601:surgery; D020390:Tooth Socket / Q000601:surgery
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D002130:Calcium Phosphates; D002951:Citrates; C105021:Guidor; D011091:Polyesters; C485817:beta-tricalcium phosphate; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid