title: [Mammary analog secretory carcinoma of the parotid gland].
abstract: Mammary analog secretory carcinoma (MASC) of the parotid gland is a rare and recently described lesion. We report the case of a 46-year-old man with a tumor of the parotid gland which was carried to the diagnosis of MASC. Diagnostic was confirmed by highlighting the ETV6-NTRK3 gene translocation. However, some morphologic and immunohistochemical features are suggestive of this entity. This carcinoma should be distinguished from its main differential diagnoses: acinic cell carcinoma and low grade cribriform cystadenocarcinoma.
authors.affiliation: Service d'anatomie et cytologie pathologique, CHU Pointe-à-Pitre/Abymes, BP 465, 97159 Pointe-à-Pitre cedex, Guadeloupe. Electronic address: maxouguerin@gmail.com.
authors.forename: Maxime
authors.initials: M
authors.lastname: Guérin
authors.affiliation: Service d'anatomie et cytologie pathologique, CHU Pointe-à-Pitre/Abymes, BP 465, 97159 Pointe-à-Pitre cedex, Guadeloupe.
authors.forename: Abdoulaye
authors.initials: A
authors.lastname: Diedhiou
authors.affiliation: Service ORL, CHU Pointe à Pitre/Abymes, Guadeloupe, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Nallet
authors.affiliation: Service ORL, CHU Pointe à Pitre/Abymes, Guadeloupe, France.
authors.forename: Suzy
authors.initials: S
authors.lastname: Duflo
authors.affiliation: Service de pathologie, unité de cytogénétique, institut Curie, Paris, France.
authors.forename: Marick
authors.initials: M
authors.lastname: Laé
authors.affiliation: Service de pathologie, hôpital Lariboisiere, Paris, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Wassef
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002277:Carcinoma / Q000737:chemistry / Q000235:genetics / Q000473:pathology*; D018267:Carcinoma, Acinar Cell; D003536:Cystadenocarcinoma; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D015514:Oncogene Proteins, Fusion / Q000235:genetics; D010307:Parotid Neoplasms / Q000737:chemistry / Q000235:genetics / Q000473:pathology*; D014178:Translocation, Genetic; D020812:Receptor, trkC; D000097764:ETS Translocation Variant 6 Protein
chemical_list: D014408:Biomarkers, Tumor; D015514:Oncogene Proteins, Fusion; C484319:ETV6-NTRK3 fusion protein, human; D020812:Receptor, trkC; D000097764:ETS Translocation Variant 6 Protein
keywords: Analogue des carcinomes sécrétoires mammaires; Carcinome salivaire sécrétoire; ETV6; Glande parotide; Mammary analog secretory carcinoma; Parotid gland