title: Extracorporeal circulatory approaches to treat acute respiratory distress syndrome.
abstract: The early history of extracorporeal membrane oxygenation (ECMO) for adult patients with the acute respiratory distress syndrome (ARDS) evolved slowly over decades, a consequence of extracorporeal technology with high risk and unclear benefit. However, advances in component technology, accumulating evidence, and growing experience in recent years have resulted in a resurgence of interest in ECMO. Extracorporeal support, though currently lacking high-level evidence, has the potential to improve outcomes, including survival, in ARDS. In the near future, novel extracorporeal management strategies may, in fact, lead to a new paradigm in the approach to certain patients with ARDS.
authors.affiliation: Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physicians and Surgeons, PH 8E 101, New York, NY 10032, USA.
authors.forename: Darryl
authors.initials: D
authors.lastname: Abrams
authors.affiliation: Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physicians and Surgeons, PH 8E 101, New York, NY 10032, USA. Electronic address: hdb5@cumc.columbia.edu.
authors.forename: Daniel
authors.initials: D
authors.lastname: Brodie
mesh_terms: D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D006801:Humans; D012128:Respiratory Distress Syndrome / Q000628:therapy*
keywords: Acute respiratory distress syndrome; Extracorporeal carbon dioxide removal; Extracorporeal membrane oxygenation; Lung-protective ventilation; Respiratory failure