title: Congenital multifocal rhabdoid tumor: a case with peculiar biological behavior and different response to treatment according to location (central nervous system and kidney).
abstract: Atypical teratoid/rhabdoid tumor (AT/RT) of the central nervous system and malignant rhabdoid tumor of the kidney (MRTK) may present with different responses to chemotherapy and outcomes. We describe the case of an infant with multifocal rhabdoid tumor with different behavior and response to treatment, depending on the anatomic site.
authors.affiliation: Università degli Studi di Genova, Genova, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Pio
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Milanaccio
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Samantha
authors.initials: S
authors.lastname: Mascelli
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Raso
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Nozza
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Angela R
authors.initials: AR
authors.lastname: Sementa
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Armando
authors.initials: A
authors.lastname: Cama
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Piero
authors.initials: P
authors.lastname: Buffa
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Avanzini
authors.affiliation: Università degli Studi di Genova, Genova, Italy.
authors.forename: Marianna
authors.initials: M
authors.lastname: Vannati
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Valeria
authors.initials: V
authors.lastname: Capra
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Edoardo
authors.initials: E
authors.lastname: Lanino
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Rossi
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Morana
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Gian M
authors.initials: GM
authors.lastname: Magnano
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy.
authors.forename: Mariasavina
authors.initials: M
authors.lastname: Severino
authors.affiliation: Istituto Giannina Gaslini, Genova, Italy. Electronic address: mluisagarre@ospedale-gaslini.ge.it.
authors.forename: Maria L
authors.initials: ML
authors.lastname: Garrè
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000151:congenital / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D002531:Cerebellum / Q000000981:diagnostic imaging / Q000473:pathology; D002868:Chromosomal Proteins, Non-Histone / Q000235:genetics; D018389:Codon, Nonsense / Q000235:genetics; D003131:Combined Modality Therapy; D004268:DNA-Binding Proteins / Q000235:genetics; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000151:congenital / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D008297:Male; D011859:Radiography; D018335:Rhabdoid Tumor / Q000151:congenital / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D000071796:SMARCB1 Protein; D013724:Teratoma / Q000151:congenital / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D014157:Transcription Factors / Q000235:genetics
chemical_list: D000970:Antineoplastic Agents; D002868:Chromosomal Proteins, Non-Histone; D018389:Codon, Nonsense; D004268:DNA-Binding Proteins; D000071796:SMARCB1 Protein; C513266:SMARCB1 protein, human; D014157:Transcription Factors
keywords: AT/RT; MRTK; Rhabdoid tumor