title: Value of prostate gland volume measurement by transrectal US in prediction of the severity of lower urinary tract symptoms.
abstract: OBJECTIVE
  The aim of our study was to analyze the value of prostate gland volume measurement by transrectal ultrasonography (TRUS) in prediction of lower urinary tract symptoms (LUTS).
  
  
  METHODS
  One hundred and one patients undergoing TRUS guided core needle prostate biopsy for the investigation of prostate cancer were prospectively evaluated. All patients had filled in the international prostate symptom score (IPSS) scala, tested for PSA and prostate volume measurement was done by TRUS prior to biopsy. According to their biopsy results, patients were divided into two groups: negative and positive for malignancy.
  
  
  RESULTS
  There was a significant but low correlation of 0.37 between IPSS and prostate volume measurement by TRUS (p=0.001). Serum free prostate specific antigen (fPSA), total PSA (tPSA), ratio of fPSA to tPSA and PSA density did not show a statistically significant correlation with IPSS (p>0.05). No statistically significant difference in IPSS between the benign and malignant groups (p=0.681) was found. In the benign group, mean IPSS was 14.59 +/- 8.73, range: 0-35 while in the malignant group, mean IPSS was 15.33 +/- 9.22, range: 3-28.
  
  
  CONCLUSIONS
  Prostate volume measurement by TRUS is a poor predictor for the determination of the severity of LUTS and IPSS should be primarily considered for the determination of the severity of LUTS. On the other hand according to this study conducted with patients who were at their first set of prostate biopsy, IPSS cannot be used as a predictor of malignancy. PSA values are not related to IPSS.
authors.affiliation: Diskapi Yildirim Beyazit Training and Research Hospital, Department of Radiology, Ankara, Turkey. idil.gunes.tatar@gmail.com.
authors.forename: Idil Gunes
authors.initials: IG
authors.lastname: Tatar
authors.affiliation: Diskapi Yildirim Beyazit Training and Research Hospital, Department of Radiology, Ankara, Turkey.
authors.forename: Onur
authors.initials: O
authors.lastname: Ergun
authors.affiliation: Diskapi Yildirim Beyazit Training and Research Hospital, Department of Radiology, Ankara, Turkey.
authors.forename: Pinar
authors.initials: P
authors.lastname: Celtikci
authors.affiliation: Diskapi Yildirim Beyazit Training and Research Hospital, Department of Radiology, Ankara, Turkey.
authors.forename: Erdem
authors.initials: E
authors.lastname: Birgi
authors.affiliation: Diskapi Yildirim Beyazit Training and Research Hospital, Department of Radiology, Ankara, Turkey.
authors.forename: Baki
authors.initials: B
authors.lastname: Hekimoglu
mesh_terms: D001707:Biopsy, Needle; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000150:complications* / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology; D011471:Prostatic Neoplasms / Q000150:complications* / Q000473:pathology; D012720:Severity of Illness Index; D014463:Ultrasonography