title: An update on the epidemiology and pathology of African swine fever.
abstract: African swine fever (ASF) is one of the most important infectious diseases of swine and has major negative consequences for affected countries. ASF is present in many sub-Saharan countries, Sardinia and several countries of eastern and central Europe, where its continuous spread has the swine industry on heightened alert. ASF is a complex disease for which no vaccine or treatment is available, so its control is based on early detection and rapid control of spread. For a robust and reliable early detection programme it is essential to be able to recognize the clinical signs and pathological changes of ASF, keeping in mind that in most cases the first introductions don't show high mortality nor characteristic clinical signs or lesions, but fever and some hemorrhagic lymph nodes. Knowledge of the main characteristics of this infection, including its current distribution and routes of transmission, is also essential for preventing and controlling ASF. This review addresses each of these topics and aims to update knowledge of the disease in order to improve early detection of ASF in the field and allow implementation of public health programmes.
authors.affiliation: Centro VISAVET and Animal Health Department, Universidad Complutense de Madrid, Av. Puerta de Hierro SN 28040, Madrid, Spain. Electronic address: jmvizcaino@ucm.es.
authors.forename: J M
authors.initials: JM
authors.lastname: Sánchez-Vizcaíno
authors.affiliation: Centro VISAVET and Animal Health Department, Universidad Complutense de Madrid, Av. Puerta de Hierro SN 28040, Madrid, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Mur
authors.affiliation: Department of Comparative Pathology, Universidad de Córdoba, Córdoba, Spain.
authors.forename: J C
authors.initials: JC
authors.lastname: Gomez-Villamandos
authors.affiliation: Department of Comparative Pathology, Universidad de Córdoba, Córdoba, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Carrasco
mesh_terms: D000357:African Swine Fever / Q000453:epidemiology* / Q000473:pathology*; D000818:Animals; D013552:Swine
keywords: African swine fever; clinical signs; differential diagnosis; lesions