title: Bloodstream infections and central line-associated bloodstream infections.
abstract: It is estimated that more than 575,000 individuals develop bloodstream infections (BSI) annually in North America, accounting for nearly 80,000 deaths. Central line-associated BSI (CLABSI) is a major contributor to the cost of health care. Although primary BSI may be seen by the surgeon, a secondary BSI is more likely to be encountered, especially CLABSI. Prompt identification of the source of infection in patients with secondary BSI is paramount. This practice allows early source control and initiation of appropriate antimicrobial therapy, with subsequent improvement in outcomes. An understanding of evidence-based preventative measures and bundles is important.
authors.affiliation: Division of Acute Care Surgery, Department of Surgery, Palmetto Health Richland, 9 Medical Park Drive, Suite 450, Columbia, SC 29203, USA. Electronic address: christopher.watson@palmettohealth.org.
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Watson
authors.affiliation: Division of Infectious Diseases, Department of Medicine, University of South Carolina School of Medicine, 2 Medical Park, Suite 502, Columbia, SC 29203, USA.
authors.forename: Majdi N
authors.initials: MN
authors.lastname: Al-Hasan
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D055499:Catheter-Related Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D003428:Cross Infection / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D017053:Infection Control / Q000379:methods; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents
keywords: Bacteremia; Bloodstream infection(s); Catheter-related bloodstream infection(s); Septicemia