title: Clinical outcomes after pancreaticoduodenectomy in elderly patients at middle-volume center.
abstract: OBJECTIVE
  It has been reported that age and hospital volume are risk factors after pancreaticoduodenectomy (PD), however the mortality rate after PD at middle volume center is decreasing by surgical advances and recently PD in the elderly patients is safely performed. The aim of this study is to evaluate the safety and feasibility of PD in the patients over 80 years of age at middle-volume center.
  
  
  METHODS
  60 patients who underwent PD between 2004 and 2012 were divided into two groups (≥80 and <80years). The clinical outcomes of the two groups were retrospectively analyzed.
  
  
  RESULTS
  There were no statistical differences in terms of preoperative parameters, co-morbidity, perioperative data, morbidity, mortality and postoperative hospital stay. We achieved zero mortality in patients over 80 years of age and 40% of them are alive without recurrence.
  
  
  CONCLUSIONS
  Clinical outcomes after PD in the elderly patients at middle-volume center are acceptable. Age and hospital volume are not necessarily risk factors after PD.
authors.forename: Teruyuki
authors.initials: T
authors.lastname: Usuba
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Takeda
authors.forename: Keishirou
authors.initials: K
authors.lastname: Murakami
authors.forename: Yujirou
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Nobuyoshi
authors.initials: N
authors.lastname: Hanyu
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005240:Feasibility Studies; D005260:Female; D006773:Hospitals, Municipal; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000009:adverse effects / Q000401:mortality; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome