title: Poisoning by Ipomoea asarifolia in lambs by the ingestion of milk from ewes that ingest the plant.
abstract: Two experiments, each with 10 pregnant ewes (8 treated and 2 controls) were performed to determine if nursing lambs of lactating ewes become intoxicated when the ewes ingest Ipomoea asarifolia but do not show clinical signs themselves. In the first experiment the sheep grazed I. asarifolia in the field while in the second, sheep were maintained in individual bays consuming dry I. asarifolia at 10% and 20% into their ration. In both experiments the lambs remained confined, consuming only their mother's milk. Four of 8 lambs in the grazing experiment and the 4 nursing lambs from the ewes given 20% I. asarifolia showed signs of I. asarifolia poisoning. These results confirm that the tremorgenic compound of I. asarifolia or its toxic metabolites are eliminated in milk and can intoxicate nursing lambs.
authors.affiliation: Veterinary Hospital, Federal University of Campina Grande, Patos, CEP 58700-310 Paraíba, Brazil.
authors.forename: Kleber F
authors.initials: KF
authors.lastname: Carvalho de Lucena
authors.affiliation: Veterinary Hospital, Federal University of Campina Grande, Patos, CEP 58700-310 Paraíba, Brazil.
authors.forename: Jussara M N
authors.initials: JM
authors.lastname: Rodrigues
authors.affiliation: Veterinary Hospital, Federal University of Campina Grande, Patos, CEP 58700-310 Paraíba, Brazil.
authors.forename: Édipo M
authors.initials: ÉM
authors.lastname: Campos
authors.affiliation: Veterinary Hospital, Federal University of Campina Grande, Patos, CEP 58700-310 Paraíba, Brazil.
authors.forename: Antônio F M
authors.initials: AF
authors.lastname: Dantas
authors.affiliation: Poisonous Plant Research Laboratory, Agriculture Research Service, U.S. Department of Agriculture, 1150 E. 1400 N., Logan, UT 84341, United States.
authors.forename: James A
authors.initials: JA
authors.lastname: Pfister
authors.affiliation: Poisonous Plant Research Laboratory, Agriculture Research Service, U.S. Department of Agriculture, 1150 E. 1400 N., Logan, UT 84341, United States.
authors.forename: Daniel
authors.initials: D
authors.lastname: Cook
authors.affiliation: Veterinary Hospital, Federal University of Campina Grande, Patos, CEP 58700-310 Paraíba, Brazil. Electronic address: rmtmed@uol.com.br.
authors.forename: Rosane M T
authors.initials: RM
authors.lastname: Medeiros
authors.affiliation: Veterinary Hospital, Federal University of Campina Grande, Patos, CEP 58700-310 Paraíba, Brazil. Electronic address: franklin.riet@pq.cnpq.br.
authors.forename: Franklin
authors.initials: F
authors.lastname: Riet-Correa
mesh_terms: D000818:Animals; D001938:Brazil; D005260:Female; D027741:Ipomoea / Q000737:chemistry* / Q000633:toxicity; D008431:Maternal-Fetal Exchange / Q000502:physiology*; D008892:Milk / Q000737:chemistry*; D010939:Plant Poisoning / Q000662:veterinary*; D011247:Pregnancy; D012756:Sheep; D012757:Sheep Diseases / Q000139:chemically induced*; D014202:Tremor / Q000139:chemically induced / Q000662:veterinary*
keywords: Milk toxicity; Sheep; Toxic plants; Tremorgenic toxins