title: Establishment of a method for determination of arsenic species in seafood by LC-ICP-MS.
abstract: An analytical method for determination of arsenic species (inorganic arsenic (iAs), methylarsonic acid (MA), dimethylarsinic acid (DMA), arsenobetaine (AB), trimethylarsine oxide (TMAO) and arsenocholine (AC)) in Brazilian and Spanish seafood samples is reported. This study was focused on extraction and quantification of inorganic arsenic (iAs), the most toxic form. Arsenic speciation was carried out via LC with both anionic and cationic exchange with ICP-MS detection (LC-ICP-MS). The detection limits (LODs), quantification limits (LOQs), precision and accuracy for arsenic species were established. The proposed method was evaluated using eight reference materials (RMs). Arsenobetaine was the main species found in all samples. The total and iAs concentration in 22 seafood samples and RMs ranged between 0.27-35.2 and 0.02-0.71 mg As kg(-1), respectively. Recoveries ranging from 100% to 106% for iAs, based on spikes, were achieved. The proposed method provides reliable iAs data for future risk assessment analysis.
authors.affiliation: Instituto de Química, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
authors.forename: Ariane V
authors.initials: AV
authors.lastname: Zmozinski
authors.affiliation: Department of Analytical Chemistry, University of Barcelona, Martí i Franquès 1-11, E-08028 Barcelona, Spain.
authors.forename: Toni
authors.initials: T
authors.lastname: Llorente-Mirandes
authors.affiliation: Department of Analytical Chemistry, University of Barcelona, Martí i Franquès 1-11, E-08028 Barcelona, Spain. Electronic address: fermin.lopez@ub.edu.
authors.forename: José F
authors.initials: JF
authors.lastname: López-Sánchez
authors.affiliation: Instituto de Química, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
authors.forename: Márcia M
authors.initials: MM
authors.lastname: da Silva
mesh_terms: D001151:Arsenic / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005504:Food Analysis / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*; D017747:Seafood / Q000032:analysis*
chemical_list: D001151:Arsenic
keywords: Arsenic speciation; Certified reference materials (CRMs); Inorganic arsenic; Liquid chromatography-inductively coupled plasma-mass spectrometry (LC-ICP-MS); Seafood