title: Myxoid fibrosarcoma of the left atrium and ventricle in pregnancy.
abstract: Myxoid fibrosarcoma is rare in adults, and presentation during pregnancy is extremely rare. We report a woman who presented at 20+1 weeks of gestation with a 1-month history of swollen legs, exertional dyspnea, and cough with frothy sputum. Dual-source computed tomography and transthoracic echocardiography showed a left atrial mass. The dead fetus was delivered by caesarean section. Two weeks later, she underwent resection of the intracardiac mass and mitral valve replacement. Histopathologic examination showed myxoid fibrosarcoma. The patient refused postoperative adjuvant chemotherapy and radiotherapy. After 1 year, she had no apparent complications, and echocardiography showed no evidence of recurrence.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, the First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, the First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
authors.forename: Xiangxiang
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, the First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
authors.forename: Buqing
authors.initials: B
authors.lastname: Ni
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, the First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
authors.forename: Weidong
authors.initials: W
authors.lastname: Gu
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, the First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
authors.forename: Haoliang
authors.initials: H
authors.lastname: Sun
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, the First Affiliated Hospital, Nanjing Medical University, Nanjing, China.
authors.forename: Yongfeng
authors.initials: Y
authors.lastname: Shao
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, the First Affiliated Hospital, Nanjing Medical University, Nanjing, China. Electronic address: shijiangzhang@hotmail.com.
authors.forename: Shijiang
authors.initials: S
authors.lastname: Zhang
mesh_terms: D000328:Adult; D006348:Cardiac Surgical Procedures / Q000379:methods*; D002585:Cesarean Section; D017024:Chemotherapy, Adjuvant; D004452:Echocardiography; D005260:Female; D005354:Fibrosarcoma / Q000175:diagnosis* / Q000628:therapy; D005500:Follow-Up Studies; D006325:Heart Atria; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000628:therapy; D006352:Heart Ventricles; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D018714:Radiotherapy, Adjuvant