title: Bilocal recurrence of a neuroendocrine carcinoma of the small intestine: A case report.
abstract: BACKGROUND
  Neuroendocrine tumors of the small intestine represent about half of all small intestine neoplasms. Recurrence after surgery with curative intention is frequently observed but recurrence rate has not yet been described or analyzed sufficiently.
  
  
  METHODS
  In this case bilocal recurrence 4 years after curative surgery of an ileocoecal neuroendocrine carcinoma was observed in a 64 year old female. Diagnosis and follow-up was carried out as proposed in current ENETS guidelines using somatostatin receptor scintigraphy for primary diagnosis and Ga-DOTATOC-PET/CT in follow-up.
  
  
  CONCLUSIONS
  We can confirm that PET/CT for somatostatin receptor imaging shows good sensitivity in detecting neuroendocrine neoplasms and should be preferred for diagnostic, if available. For individual adaptation of follow-up procedures, as far as time intervals and preferred imaging methods are concerned, research on recurrence rate and long term outcome after curative surgery should be extended.
  
  
  CONCLUSIONS
  Livelong follow-up after surgical resection of neuroendocrine tumors is necessary and Ga-DOTA/TOC-PET/CT should be the method of choice, if available.
authors.affiliation: Department of General Surgery, Kantonsspital Graubünden, Loestrasse 170, CH-7000 Chur, Switzerland. Electronic address: Peiffer.simon@gmx.de.
authors.forename: S
authors.initials: S
authors.lastname: Peiffer
authors.affiliation: Department of Oncology, Kantonsspital Graubünden, Loestrasse 170, CH-7000 Chur, Switzerland. Electronic address: Richard.cathomas@ksgr.ch.
authors.forename: R
authors.initials: R
authors.lastname: Cathomas
authors.affiliation: Department of General Surgery, Kantonsspital Graubünden, Loestrasse 170, CH-7000 Chur, Switzerland. Electronic address: Peter.villiger@ksgr.ch.
authors.forename: P
authors.initials: P
authors.lastname: Villiger
keywords: Neuroendocrine tumor; Recurrence; Somatostatin receptor imaging