title: A comparison of postoperative effects of bariatric surgery on medical markers of morbidity.
abstract: BACKGROUND
  Bariatric surgery reduces the prevalence of diabetes and improves lipid profiles. Low-density lipoprotein particle (LDL-P) is a more accurate predictor of cardiovascular events than high-density lipoprotein (HDL) and LDL cholesterol. The effects of bariatric procedures on LDL-P have not been previously reported.
  
  
  METHODS
  Two hundred thirty patients undergoing bariatric surgery, including gastric bypass, sleeve gastrectomy, and laparoscopic adjustable gastric band placement at a single institution were included. HDL, LDL, hemoglobin A1c, and LDL-P were measured preoperatively and at 3, 6, and 12 months postoperatively. Weight was recorded at baseline and after 1 year.
  
  
  RESULTS
  There was a decrease in serum LDL-P levels, averaging 472.58 (P < .0001) over 1 year. HDL levels increased. Hemoglobin A1c and LDL levels declined. On average, patients lost 58% of excess weight.
  
  
  CONCLUSIONS
  LDL-P significantly decreased after bariatric surgery in relation to weight loss. It may be inferred that bariatric surgery decreases the risk of cardiovascular events.
authors.affiliation: Baylor Scott & White, MS-01-712, 2401 S. 31st Street, Temple, TX 76508, USA. Electronic address: GBONNER@SW.ORG.
authors.forename: Gwen L
authors.initials: GL
authors.lastname: Bonner
authors.affiliation: Fourth Year Medical Student, Texas A&M Health Science Center, Temple, TX, USA.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Nagy
authors.affiliation: Department of Biostatistics, Texas A&M Health Science Center, Temple, TX, USA.
authors.forename: Daniel C
authors.initials: DC
authors.lastname: Jupiter
authors.affiliation: Minimally Invasive Surgery and Bariatric Surgery, Texas A&M Health Science Center, Temple, TX, USA.
authors.forename: Joaquin A
authors.initials: JA
authors.lastname: Rodriguez
authors.affiliation: Minimally Invasive Surgery and Bariatric Surgery, Texas A&M Health Science Center, Temple, TX, USA.
authors.forename: Richard E
authors.initials: RE
authors.lastname: Symmonds
authors.affiliation: Minimally Invasive Surgery and Bariatric Surgery, Texas A&M Health Science Center, Temple, TX, USA.
authors.forename: Robert O
authors.initials: RO
authors.lastname: Carpenter
mesh_terms: D050110:Bariatric Surgery; D015415:Biomarkers / Q000097:blood*; D003324:Coronary Artery Disease / Q000097:blood / Q000517:prevention & control; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000517:prevention & control; D006973:Hypertension / Q000097:blood / Q000517:prevention & control; D010535:Laparoscopy; D008055:Lipids / Q000097:blood; D008297:Male; D009017:Morbidity; D009767:Obesity, Morbid / Q000097:blood* / Q000601:surgery*; D012189:Retrospective Studies; D015431:Weight Loss
chemical_list: D015415:Biomarkers; D006442:Glycated Hemoglobin; D008055:Lipids
keywords: Bariatric surgery; Cardiovascular risk; Cholesterol; LDL particle; Obesity