title: Roseoloviruses: unmet needs and research priorities: perspective.
abstract: The human roseoloviruses, human herpesviruses 6A (HHV-6A), HHV-6B, and HHV-7, are highly prevalent viruses that typically cause fever/rash illnesses such as roseola during early life primary infections. They also cause significant neurologic disease and complications following stem cell and solid organ transplantation, and have suggestive but less certain etiologic associations with other neurologic diseases and immunologic disorders. The US National Institute of Allergy and Infectious Diseases recently sponsored a workshop (Roseoloviruses: Clinical Impact, Interventions, and Research Needs) to discuss disease associations, novel biology, and the many unmet research needs related to Roseoloviruses. This perspective is a distillation of the workshop's presentations and discussions, with a focus on the more general research priorities that emerged.
authors.affiliation: Division of Pediatric Infectious Diseases, University of Rochester Medical Center, Rochester, NY 14642, United States. Electronic address: mary_caserta@urmc.rochester.edu.
authors.forename: Mary T
authors.initials: MT
authors.lastname: Caserta
authors.affiliation: Department of Molecular Genetics & Microbiology, Stony Brook University, Stony Brook, NY 11794, United States.
authors.forename: Laurie T
authors.initials: LT
authors.lastname: Krug
authors.affiliation: Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, MI 48201, United States.
authors.forename: Philip E
authors.initials: PE
authors.lastname: Pellett
mesh_terms: D035843:Biomedical Research / Q000639:trends; D002202:Capital Financing; D006291:Health Policy; D006801:Humans; D012106:Research; D019211:Roseolovirus / Q000502:physiology*; D019349:Roseolovirus Infections / Q000453:epidemiology* / Q000517:prevention & control / Q000628:therapy