title: Aqueous reaction quantification after phacoemulsification: Fourier-domain optical coherence tomography versus slitlamp biomicroscopy.
abstract: OBJECTIVE
  To compare anterior chamber cell detection after phacoemulsification between Fourier-domain optical coherence tomography (OCT) and slitlamp biomicroscopy.
  
  
  METHODS
  Observational prospective comparative case series.
  
  
  METHODS
  Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
  
  
  METHODS
  Eyes with preoperative nuclear opalescence (NO) grades 1 to 3 that had phacoemulsification with posterior chamber intraocular lens implantation were included. Slitlamp biomicroscopy and Fourier-domain OCT (Cirrus HD) of the anterior chamber were performed 1 day postoperatively. The results were evaluated, and a correlation analysis between the results and preoperative NO, effective phacoemulsification time (EPT), postoperative central corneal thickness (CCT), and intraocular pressure (IOP) was performed.
  
  
  RESULTS
  The preoperative NO grade was 1 in 20 eyes, 2 in 55 eyes, and 3 in 42 eyes. Anterior chamber grading was possible by slitlamp biomicroscopy and Fourier-domain OCT in 106 eyes (90.5%) and 117 eyes (100.0%), respectively. A positive correlation between slitlamp biomicroscopy and OCT grading was noted (R(2) = 0.986, P=.000). Slitlamp grading was not possible in 11 eyes (9.4%) with corneal edema (mean CCT 754 μm ± 44.2 [SD]); OCT detected cells in all 11 eyes. There was a difference in slitlamp grading and OCT grading in 7 eyes (6.6%). There was a significant correlation between the OCT cell count and the EPT (P=.000) and NO (P=.000).
  
  
  CONCLUSIONS
  Fourier-domain OCT was as reliable as slitlamp biomicroscopy in assessing postoperative anterior chamber cells.
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Dhivya Ashok
authors.initials: DA
authors.lastname: Kumar
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India. Electronic address: dragarwal@vsnl.com.
authors.forename: Amar
authors.initials: A
authors.lastname: Agarwal
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Soundari
authors.initials: S
authors.lastname: Sivangnanam
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Atanu
authors.initials: A
authors.lastname: Ghorai
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Bhavani
authors.initials: B
authors.lastname: Murugan
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Sathiya
authors.initials: S
authors.lastname: Packiyalakshmi
authors.affiliation: From Dr. Agarwal's Eye Hospital and Eye Research Centre, Chennai, India.
authors.forename: Radika
authors.initials: R
authors.lastname: Chandrasekar
mesh_terms: D001082:Aqueous Humor / Q000166:cytology*; D018916:Blood-Aqueous Barrier; D002452:Cell Count; D003315:Cornea / Q000473:pathology; D063171:Corneal Pachymetry; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D019654:Lens Implantation, Intraocular; D007962:Leukocytes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011446:Prospective Studies; D066167:Slit Lamp; D041623:Tomography, Optical Coherence / Q000379:methods*