title: The influence of psychological stress on arginine vasopressin concentration in the human plasma and cerebrospinal fluid.
abstract: Psychological stress is strain affecting the intangible self, caused by problems in adaptation, perception, and emotions. Previous studies have demonstrated that arginine vasopressin (AVP) plays an important role in psychological stress. The goal of present study was to investigate the interaction between AVP release and cardiovascular functions by measuring AVP concentration and recording blood pressure or heart rate during psychological stress in human. The results showed that (1) psychological stress not only increased the systolic blood pressure, diastolic blood pressure and heart rate, but also elevated the cortisol and AVP concentration in both plasma and CSF in a stress level-dependent manner; (2) there was a positive relationship between plasma AVP concentration and systolic blood pressure, diastolic blood pressure, heart rate or plasma cortisol concentration; (3) there was also a positive relationship between AVP concentrations in plasma and CSF AVP. The data suggested that plasma AVP, which might come from the central nervous system, might influence the cardiovascular functions during psychological stress in human.
authors.affiliation: Department of Anesthesiology, 153 Hospital of People's Liberation Army, Zhengzhou, Henan 450002, China.
authors.forename: Le-Le
authors.initials: LL
authors.lastname: Bao
authors.affiliation: Department of Burn Reconstructive Surgery, 153 Hospital of People's Liberation Army, Zhengzhou, Henan 450002, China.
authors.forename: Wen-Quan
authors.initials: WQ
authors.lastname: Jiang
authors.affiliation: Xinxiang Institute for New Medicine, Xinxiang, Henan 453003, China.
authors.forename: Fang-Jie
authors.initials: FJ
authors.lastname: Sun
authors.affiliation: Jiangsu Su Bei People's Hospital (Clinical College of Yangzhou University), Yangzhou, Jiangsu 225001, China.
authors.forename: Da-Xin
authors.initials: DX
authors.lastname: Wang
authors.affiliation: Department of Pharmacy, The Second Affiliated Hospital of Xinxiang Medical University (Henan Provincial Mental Hospital), Xinxiang, Henan 453002, China.
authors.forename: Yan-Juan
authors.initials: YJ
authors.lastname: Pan
authors.affiliation: Department of Neurology, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan 453000, China.
authors.forename: Zhi-Xiu
authors.initials: ZX
authors.lastname: Song
authors.affiliation: Henan Provincial Mental Hospital, Xinxiang, Henan 453002, China.
authors.forename: Chang-Hong
authors.initials: CH
authors.lastname: Wang
authors.affiliation: Xinxiang Institute for New Medicine, Xinxiang, Henan 453003, China; Standard Technological Co. Ltd., Xinxiang, Henan 453003, China. Electronic address: bcd2009@126.com.
authors.forename: Jun
authors.initials: J
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D001127:Arginine Vasopressin / Q000097:blood* / Q000134:cerebrospinal fluid*; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000134:cerebrospinal fluid; D008297:Male; D013315:Stress, Psychological / Q000097:blood* / Q000134:cerebrospinal fluid*; D055815:Young Adult
chemical_list: D001127:Arginine Vasopressin; D006854:Hydrocortisone
keywords: Arginine vasopressin; Blood pressure; Cortisol; Heart rate; Psychological stress