title: Primary adnexal angiosarcoma masquerading as periorbital hematoma.
abstract: We report an elderly woman who was anticoagulated and presented with a recent history of right-sided orbital contusion and a periorbital hematoma without clinical or radiological evidence of focal mass or orbital involvement. She was initially treated conservatively. Continued progression of adnexal swelling and erythema prompted further investigation, however. There was no improvement with surgical drainage alone; biopsy revealed angiosarcoma. The discovery of this vascular tumor underscores the importance of a reconsideration of the diagnosis in the face of counterintuitive findings. Additionally, we emphasize the need to consider malignancy in the differential diagnosis of prolonged periorbital swelling, regardless of a history of recent trauma.
authors.affiliation: Ophthalmic Plastic Surgery, Department of Ophthalmology, Lions Eye Institute, Albany Medical College, Albany, NY, USA. Electronic address: nicole.ann.lemanski@gmail.com.
authors.forename: Nicole
authors.initials: N
authors.lastname: Lemanski
authors.affiliation: Ophthalmic Plastic Surgery, Department of Ophthalmology, Lions Eye Institute, Albany Medical College, Albany, NY, USA.
authors.forename: Martha
authors.initials: M
authors.lastname: Farber
authors.affiliation: Ophthalmic Plastic Surgery, Department of Ophthalmology, Lions Eye Institute, Albany Medical College, Albany, NY, USA.
authors.forename: Bryant P
authors.initials: BP
authors.lastname: Carruth
authors.affiliation: Ophthalmic Plastic Surgery, Department of Ophthalmology, Lions Eye Institute, Albany Medical College, Albany, NY, USA.
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Wladis
mesh_terms: D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000378:metabolism; D001706:Biopsy; D003937:Diagnosis, Differential; D005142:Eyelid Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D005260:Female; D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D006406:Hematoma / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D009363:Neoplasm Proteins / Q000378:metabolism; D013508:Ophthalmologic Surgical Procedures; D009916:Orbital Diseases / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D010307:Parotid Neoplasms / Q000175:diagnosis / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins
keywords: angiosarcoma; primary adnexal angiosarcoma