title: Drug and vaccine allergy.
abstract: Most children with a history of penicillin allergy are labeled allergic and denied treatment with penicillin and sometimes other beta-lactam antibiotics. Most of these children never were or are no longer allergic to penicillin. Penicillin skin testing and oral challenge can identify patients who are not currently allergic, allowing them to be treated with penicillin. Children with egg allergy are often denied influenza vaccination, because the vaccine contains a small amount of egg protein. However, recent studies have demonstrated that children with even severe egg allergy can safely receive the vaccine, reducing their risk of the morbidity and mortality associated with influenza.
authors.affiliation: Division of Allergy, Asthma, and Immunology, Scripps Clinic, 3811 Valley Centre Drive, San Diego, CA 92130, USA. Electronic address: kelso.john@scrippshealth.org.
authors.forename: John M
authors.initials: JM
authors.lastname: Kelso
mesh_terms: D002648:Child; D004342:Drug Hypersensitivity / Q000276:immunology*; D021181:Egg Hypersensitivity / Q000276:immunology; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects* / Q000276:immunology; D010406:Penicillins / Q000009:adverse effects* / Q000276:immunology; D012882:Skin Tests; D014581:Urticaria / Q000276:immunology; D014611:Vaccination / Q000009:adverse effects*
chemical_list: D007252:Influenza Vaccines; D010406:Penicillins
keywords: Allergy; Beta-lactam; Egg allergy; Influenza vaccination; Penicillin