title: Prevalence of pre-stroke sleep apnea risk and short or long sleep duration in a bi-ethnic stroke population.
abstract: BACKGROUND
  The ethnic disparity in ischemic stroke between Mexican Americans (MAs) and non-Hispanic whites (NHWs) may be partly attributable to disparities in sleep and its disorders. We therefore assessed whether pre-stroke sleep apnea symptoms (SA risk) and pre-stroke sleep duration differed between MAs and NHWs.
  
  
  METHODS
  MA and NHW ischemic stroke survivors in the Brain Attack Surveillance in Corpus Christi (BASIC) project reported sleep duration and SA symptoms on the validated Berlin questionnaire, both with respect to their pre-stroke baseline. Log binomial and linear regression models were used to test the unadjusted and adjusted (demographics and vascular risk factors) associations of high-risk Berlin scores and sleep duration with ethnicity.
  
  
  RESULTS
  Among 862 subjects, 549 (63.7%) were MA and 514 (59.6%) had a high risk of pre-stroke SA. The MA and NHW subjects showed no ethnic difference, after adjustment for potential confounders, in pre-stroke SA risk (risk ratio (95% confidence interval (CI)): 1.06 (0.93, 1.20)) or in pre-stroke sleep duration (on average MAs slept 2.0 fewer minutes than NHWs, 95% CI: -18.8, 14.9 min).
  
  
  CONCLUSIONS
  Pre-stroke SA symptoms are highly prevalent, but ethnic differences in SA risk and sleep duration appear unlikely to explain ethnic stroke disparities.
authors.affiliation: Stroke Program, The Cardiovascular Center - Stroke Program, 1500 E. Medical Center Drive - SPC#5855, Ann Arbor, MI 48109-5855, USA.
authors.forename: Lindsey B
authors.initials: LB
authors.lastname: De Lott
authors.affiliation: Stroke Program, The Cardiovascular Center - Stroke Program, 1500 E. Medical Center Drive - SPC#5855, Ann Arbor, MI 48109-5855, USA; Department of Epidemiology, 1014 SPH I, University of Michigan School of Public Health, Ann Arbor, MI 48109-2029, USA.
authors.forename: Lynda D
authors.initials: LD
authors.lastname: Lisabeth
authors.affiliation: Department of Biostatistics, M4164 SPH II, University of Michigan School of Public Health, Ann Arbor, MI 48109-2029, USA.
authors.forename: Brisa N
authors.initials: BN
authors.lastname: Sanchez
authors.affiliation: Stroke Program, The Cardiovascular Center - Stroke Program, 1500 E. Medical Center Drive - SPC#5855, Ann Arbor, MI 48109-5855, USA; Department of Epidemiology, 1014 SPH I, University of Michigan School of Public Health, Ann Arbor, MI 48109-2029, USA.
authors.forename: Lewis B
authors.initials: LB
authors.lastname: Morgenstern
authors.affiliation: Stroke Program, The Cardiovascular Center - Stroke Program, 1500 E. Medical Center Drive - SPC#5855, Ann Arbor, MI 48109-5855, USA.
authors.forename: Melinda A
authors.initials: MA
authors.lastname: Smith
authors.affiliation: Stroke Program, The Cardiovascular Center - Stroke Program, 1500 E. Medical Center Drive - SPC#5855, Ann Arbor, MI 48109-5855, USA.
authors.forename: Nelda M
authors.initials: NM
authors.lastname: Garcia
authors.affiliation: Sleep Disorders Center, University of Michigan, 1500 East Medical Center Drive, Med Inn C728, Ann Arbor, MI, USA.
authors.forename: Ronald
authors.initials: R
authors.lastname: Chervin
authors.affiliation: Stroke Program, The Cardiovascular Center - Stroke Program, 1500 E. Medical Center Drive - SPC#5855, Ann Arbor, MI 48109-5855, USA. Electronic address: devinb@umich.edu.
authors.forename: Devin L
authors.initials: DL
authors.lastname: Brown
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D017058:Mexican Americans / Q000706:statistics & numerical data; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000453:epidemiology / Q000208:ethnology; D012893:Sleep Wake Disorders / Q000150:complications* / Q000208:ethnology; D020521:Stroke / Q000208:ethnology / Q000209:etiology*; D013781:Texas / Q000453:epidemiology; D044465:White People / Q000706:statistics & numerical data
keywords: Cerebrovascular accident; Ethnicity; Insufficient sleep; Mexican American; Sleep apnea; Sleep duration; Sleep-disordered breathing; Stroke