title: Resting-state blood oxygen level-dependent functional magnetic resonance imaging for presurgical planning.
abstract: Resting-state functional MR imaging (rsfMR imaging) measures spontaneous fluctuations in the blood oxygen level-dependent (BOLD) signal and can be used to elucidate the brain's functional organization. It is used to simultaneously assess multiple distributed resting-state networks. Unlike task-based functional MR imaging, rsfMR imaging does not require task performance. This article presents a brief introduction of rsfMR imaging processing methods followed by a detailed discussion on the use of rsfMR imaging in presurgical planning. Example cases are provided to highlight the strengths and limitations of the technique.
authors.affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4525 Scott Avenue, St Louis, MO 63110, USA.
authors.forename: Mudassar
authors.initials: M
authors.lastname: Kamran
authors.affiliation: Medical Student Training Program, Washington University School of Medicine, 4525 Scott Avenue, St Louis, MO 63110, USA.
authors.forename: Carl D
authors.initials: CD
authors.lastname: Hacker
authors.affiliation: Department of Neurological Surgery, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4525 Scott Avenue, St Louis, MO 63110, USA.
authors.forename: Monica G
authors.initials: MG
authors.lastname: Allen
authors.affiliation: Department of Neurological Surgery, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4525 Scott Avenue, St Louis, MO 63110, USA.
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Mitchell
authors.affiliation: Department of Neurological Surgery, Washington University School of Medicine, 4525 Scott Avenue, St Louis, MO 63110, USA.
authors.forename: Eric C
authors.initials: EC
authors.lastname: Leuthardt
authors.affiliation: Department of Neurology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4525 Scott Avenue, St Louis, MO 63110, USA.
authors.forename: Abraham Z
authors.initials: AZ
authors.lastname: Snyder
authors.affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4525 Scott Avenue, St Louis, MO 63110, USA. Electronic address: shimonyj@mir.wustl.edu.
authors.forename: Joshua S
authors.initials: JS
authors.lastname: Shimony
mesh_terms: D001921:Brain / Q000503:physiopathology* / Q000601:surgery*; D001931:Brain Mapping / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009415:Nerve Net / Q000503:physiopathology / Q000601:surgery; D010100:Oxygen / Q000097:blood*; D011300:Preoperative Care / Q000379:methods*; D012146:Rest
chemical_list: D010100:Oxygen
keywords: Eloquent cortex; Functional MR imaging; MLP; Multilayered perceptron; RSNs; Resting-state functional MR imaging; Resting-state networks; rsfMR imaging