title: [Evaluation of grip strength in normal and obese Wistar rats submitted to swimming with overload after median nerve compression].
abstract: OBJECTIVE
  To verify the functionality through muscle grip strength in animals with obesity induced by monosodium glutamate (MSG) and in control animals, which suffered compression of the right median nerve, and treated with swimming with overload.
  
  
  METHODS
  During the first five days of life, neonatal Wistar rats received subcutaneous injections of MSG. The control group received a hypertonic saline solution. Forty-eight rats were divided into six groups: G1 (control); G2 (control + injury); G3 (control + injury + swimming); G4 (obese); G5 (obese + injury); G6 (obese + injury + swimming). The animals in groups G2, G3, G5 and G6 were submitted to compression of the median nerve and G3 and G6 groups were treated, after injury, with swimming exercise with load for three weeks. The swimming exercise had a progressive duration, according to the week, of 20, 30 and 40minutes. Muscle strength was assessed using a grip strength meter preoperatively and on the 3rd, 7th, 14th and 21st days after surgery. The results were expressed and analyzed using descriptive and inferential statistics.
  
  
  RESULTS
  When the grip strength was compared among assessments regardless of group, in the second assessment the animals exhibited lower grip strength. G1 and G4 groups had greater grip strength, compared to G2, G3, G4 and G6.
  
  
  CONCLUSIONS
  The swimming exercise with overload has not been effective in promoting improvement in muscle grip strength after compression injury of the right median nerve in control and in obese-MSG rats.
authors.affiliation: Universidade Estadual do Oeste do Paraná, Cascavel, PR, Brasil.
authors.forename: Josinéia Gresele
authors.initials: JG
authors.lastname: Coradinia
authors.affiliation: Universidade Estadual do Oeste do Paraná, Cascavel, PR, Brasil.
authors.forename: Camila Mayumi Martin
authors.initials: CM
authors.lastname: Kakihata
authors.affiliation: Universidade Estadual do Oeste do Paraná, Cascavel, PR, Brasil.
authors.forename: Regina Inês
authors.initials: RI
authors.lastname: Kunz
authors.affiliation: Universidade Estadual do Oeste do Paraná, Cascavel, PR, Brasil.
authors.forename: Tatiane Kamada
authors.initials: TK
authors.lastname: Errero
authors.affiliation: Universidade Estadual do Oeste do Paraná, Cascavel, PR, Brasil; Universidade Estadual de Campinas, Campinas, SP, Brasil.
authors.forename: Maria Lúcia
authors.initials: ML
authors.lastname: Bonfleur
authors.affiliation: Universidade Estadual do Oeste do Paraná, Cascavel, PR, Brasil; Ciências da Saúde Aplicadas ao Aparelho Locomotor, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil. Electronic address: gladson_ricardo@yahoo.com.br.
authors.forename: Gladson Ricardo Flor
authors.initials: GR
authors.lastname: Bertolini
mesh_terms: D000818:Animals; D018737:Hand Strength; D008475:Median Nerve; D009408:Nerve Compression Syndromes / Q000150:complications / Q000503:physiopathology*; D009765:Obesity / Q000150:complications / Q000503:physiopathology*; D051381:Rats; D017208:Rats, Wistar; D013550:Swimming; D016474:Weight-Bearing
keywords: Compressão nervosa; Força muscular; Muscle strength; Natação; Nerve compression; Obesidade; Obesity; Swimming