title: Isolated adult lymphadenopathy: a rare presentation of Langerhans cell histiocytosis.
abstract: BACKGROUND
  Langerhans cell histiocytosis (LCH) is a rare disease involving the proliferation of histiocytes in one or more organ systems. The presentation of LCH is more common in the pediatric population and rarely occurs within the adult population. Isolated lymph node involvement is an extremely rare presentation of the disease. The authors present a case of isolated lymph node LCH in an otherwise healthy adult female and discuss management strategies for these unusual findings.
  
  
  METHODS
  A case report of a patient at a tertiary care facility in June 2014 is discussed.
  
  
  CONCLUSIONS
  The diagnosis, clinical course, and management strategies for isolated adult LCH are discussed and reviewed.
  
  
  CONCLUSIONS
  Langerhans cell histiocytosis rarely presents with isolated lymph node involvement in adults. Management and surveillance algorithms are discussed in this unusual case of seemingly benign lymphadenopathy.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Naval Medical Center Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA. Electronic address: Jonathan.melzer@med.navy.mil.
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Melzer
authors.affiliation: F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD. Electronic address: Jessica.winters@usuhs.edu.
authors.forename: Jessica
authors.initials: J
authors.lastname: Winters
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Naval Medical Center Portsmouth, 620 John Paul Jones Circle, Portsmouth, VA. Electronic address: Allen.mitchell@med.navy.mil.
authors.forename: Allen O
authors.initials: AO
authors.lastname: Mitchell
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D008206:Lymphatic Diseases / Q000175:diagnosis*; D055815:Young Adult