title: Alignment of an acoustic manipulation device with cepstral analysis of electronic impedance data.
abstract: Acoustic particle manipulation is an emerging technology that uses ultrasonic standing waves to position objects with pressure gradients and acoustic radiation forces. To produce strong standing waves, the transducer and the reflector must be aligned properly such that they are parallel to each other. This can be a difficult process due to the need to visualise the ultrasound waves and as higher frequencies are introduced, this alignment requires higher accuracy. In this paper, we present a method for aligning acoustic resonators with cepstral analysis. This is a simple signal processing technique that requires only the electrical impedance measurement data of the resonator, which is usually recorded during the fabrication process of the device. We first introduce the mathematical basis of cepstral analysis and then demonstrate and validate it using a computer simulation of an acoustic resonator. Finally, the technique is demonstrated experimentally to create many parallel linear traps for 10 μm fluorescent beads inside an acoustic resonator.
authors.affiliation: School of Science and Engineering, University of the West of Scotland, Paisley, Scotland, UK.
authors.forename: D A
authors.initials: DA
authors.lastname: Hughes
authors.affiliation: Institute of Medical Science and Technology (IMSAT), University of Dundee, Ninewells Hospital, Dundee, UK.
authors.forename: Y
authors.initials: Y
authors.lastname: Qiu
authors.affiliation: Institute of Medical Science and Technology (IMSAT), University of Dundee, Ninewells Hospital, Dundee, UK.
authors.forename: C
authors.initials: C
authors.lastname: Démoré
authors.affiliation: Division of Cell and Developmental Biology, College of Life Sciences, University of Dundee, Dundee, Scotland, UK.
authors.forename: C J
authors.initials: CJ
authors.lastname: Weijer
authors.affiliation: Institute of Medical Science and Technology (IMSAT), University of Dundee, Ninewells Hospital, Dundee, UK.
authors.forename: S
authors.initials: S
authors.lastname: Cochran
mesh_terms: D000162:Acoustics; D003198:Computer Simulation; D017097:Electric Impedance; D014465:Ultrasonics / Q000379:methods*
keywords: Fabrication; High frequency; Manipulation; Resonator