title: CT and MR findings in 16 cases of primary neuroendocrine carcinoma in the otolaryngeal region.
abstract: Primary neuroendocrine carcinoma (NEC) is a rare malignancy in the otolaryngeal region. Computed tomography and magnetic resonance imaging findings in 16 patients with primary otolaryngeal NECs were summarized. Most of tumors occurred in the sinonasal cavity (n=9; 56.3%), then supraglottis (n=3; 18.8%). All sinonasal and one hard palate tumors were ill defined, and the other tumors were well defined. All lesions showed moderate to marked enhancement, but homogeneously in well-differentiated tumors while heterogeneously in most of poorly differentiated tumors. Most sinonasal tumors were poorly differentiated and invaded adjacent bones. Primary otolaryngeal NECs might have some distinct features related to their origin and differentiation.
authors.affiliation: Department of Radiology, The Huizhou Central municipal Hospital, No.41 Eling Rood North, Huizhou, 516001 Guangdong China. Electronic address: zhoucuiping0@126.com.
authors.forename: Cuiping
authors.initials: C
authors.lastname: Zhou
authors.affiliation: Department of Radiology, Sun Yat-Sen Memorial Hospital, SunYat-Sen University, No.107 Yanjiang Road West, Guangzhou, 510120 Guangdong, China. Electronic address: duanxiaohui-128@163.com.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Duan
authors.affiliation: Department of Radiology, First Affiliated Hospital of Shantou University Medical College, No. 57 Changping Road, Shantou, 515041 Guangdong China. Electronic address: ldl1469@126.com.
authors.forename: Danling
authors.initials: D
authors.lastname: Liao
authors.affiliation: Department of Radiology, The Huizhou Central municipal Hospital, No.41 Eling Rood North, Huizhou, 516001 Guangdong China. Electronic address: liaojunjie18@163.com.
authors.forename: Junjie
authors.initials: J
authors.lastname: Liao
authors.affiliation: Department of Radiology, Sun Yat-Sen Memorial Hospital, SunYat-Sen University, No.107 Yanjiang Road West, Guangzhou, 510120 Guangdong, China. Electronic address: shenjun@mail.sysu.edu.cn.
authors.forename: Jun
authors.initials: J
authors.lastname: Shen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D004428:Ear Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods
keywords: Computed tomography; Magnetic resonance imaging; Neuroendocrine carcinomas; Otolaryngological region