title: [Carnitine as a marker of atherosclerosis and other risks of cardiovascular diseases].
abstract: L-carnitine was first isolated from the extracts of muscle tissue in 1905 by the employees of the department of medicinal chemistry at Moscow University. Later the role of L-carnitine in both the oxidation of long chain fatty acids and the metabolism of carbohydrates was discovered. Today L-carnitine is not just a drug for the treatment of pathologies associated with its deficiency, but also a widespread dietary supplement, believed to be able to reduce weight and improve the physical qualities of a person. However, in light of the recent findings about a possible link between L-carnitine and the development of atherosclerosis, a careful assessment of the use of L-carnitine as a safe dietary supplement is required, particularly when there is no sound medical indication.
authors.forename: M
authors.initials: M
authors.lastname: Dambrova
authors.forename: M
authors.initials: M
authors.lastname: Makretskaia
authors.forename: R
authors.initials: R
authors.lastname: Vilshkersts
authors.forename: Ia
authors.initials: Ia
authors.lastname: Kuka
authors.forename: É
authors.initials: É
authors.lastname: Liepin'sh
mesh_terms: D050197:Atherosclerosis / Q000150:complications / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control; D002331:Carnitine / Q000378:metabolism / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D006801:Humans; D014803:Vitamin B Complex / Q000378:metabolism / Q000494:pharmacology
chemical_list: D015415:Biomarkers; D005231:Fatty Acids, Unsaturated; D014803:Vitamin B Complex; D002331:Carnitine