title: Pancreaticogastrostomy or pancreaticojejunostomy? Methods of digestive continuity reconstruction after pancreaticodudenectomy: a meta-analysis of randomized controlled trials.
abstract: OBJECTIVE
  Reconstruction of digestive tract after pancreaticodudenectomy now has been proved associated with pancreatic fistula and complication incidence. The meta-analysis was conducted at the appropriate time enough randomized controlled trials were reported.
  
  
  METHODS
  Systematically literature search was performed through PubMed, EMBASE and Cochrane Library database without restriction to regions, or languages, only randomized controlled trials was included. 7 studies compared pancreatogastrostomy with pancreaticojejunostomy were included for meta-analysis. Fixed and random-effects models were used to measure the pooled estimates.
  
  
  RESULTS
  Patient underwent pancreatogastrostomy after pancreatoduodenectomy suffered less pancreatic fistula(p = 0.001) and bile leakage (p = 0.02), while the operative time, hospital stay, delayed gastric emptying and overall morbidity were comparable.
  
  
  CONCLUSIONS
  Pancreatogastrostomy is a recommended anastomosis technique according to the meta-analysis due to minimize incidence of pancreatic fistula and bile leakage.
authors.affiliation: Department of Gastrointestinal Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 0086-510000, China.
authors.forename: Purun
authors.initials: P
authors.lastname: Lei
authors.affiliation: Department of Gastrointestinal Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 0086-510000, China.
authors.forename: Jiafeng
authors.initials: J
authors.lastname: Fang
authors.affiliation: Department of Gastrointestinal Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 0086-510000, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Department of Gastrointestinal Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 0086-510000, China.
authors.forename: Zongheng
authors.initials: Z
authors.lastname: Zheng
authors.affiliation: Department of Gastrointestinal Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 0086-510000, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Wei
authors.affiliation: Department of Gastrointestinal Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 0086-510000, China. Electronic address: weihbsysu@163.com.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Wei
mesh_terms: D057868:Anastomotic Leak / Q000209:etiology / Q000517:prevention & control; D001646:Bile; D005774:Gastrostomy / Q000379:methods*; D006801:Humans; D015994:Incidence; D007902:Length of Stay; D061646:Operative Time; D010179:Pancreas / Q000601:surgery*; D010185:Pancreatic Fistula / Q000209:etiology / Q000517:prevention & control*; D016577:Pancreaticoduodenectomy / Q000009:adverse effects*; D010193:Pancreaticojejunostomy / Q000009:adverse effects / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D019651:Plastic Surgery Procedures / Q000009:adverse effects / Q000379:methods*
keywords: Meta-analysis; Pancreatic fistula; Pancreaticodudenectomy; Pancreaticojejunostomy; Pancreatogastrostomy; Reconstruction