title: Long-term efficacy of the Baerveldt 250 mm2 compared with the Baerveldt 350 mm2 implant.
abstract: OBJECTIVE
  To investigate the long-term surgical outcomes of the Baerveldt 250 mm2 versus Baerveldt 350 mm2 glaucoma drainage implants (GDIs) (Abbott Laboratories Inc., Abbott Park, IL) in the treatment of refractory glaucoma.
  
  
  METHODS
  Comparative case study.
  
  
  METHODS
  A total of 89 consecutive eyes in 86 patients treated at Dean McGee Eye Institute between January 2006 and December 2008.
  
  
  METHODS
  We retrospectively reviewed patient data from the following postoperative visits: 1 week, 1 month, 2 months, 3 months, 6 months, and every 3 months thereafter. Postoperative complications were also recorded. The mean follow-up time was 40 months (range, 2-78 months) for the Baerveldt 250 mm2 group and 31 months (range, 3-75 months) for the Baerveldt 350 mm2 group.
  
  
  METHODS
  The primary outcome measure was surgical success. Secondary outcome measures included visual acuity (VA), intraocular pressure (IOP), and number of medications.
  
  
  RESULTS
  There was no difference in surgical success (P=0.98). No significant differences were observed in VA measured using the logarithm of the minimum angle of resolution (logMAR) scale, IOP, and number of medications at the last visit (P=0.09, 0.23, and 0.82, respectively). Complication and failure rates were comparable (P=0.82 and 0.64, respectively).
  
  
  CONCLUSIONS
  With a mean follow-up of 40 and 31 months, no differences in surgical success, VA, IOP, number of medications at the last visit, and complication/failure rates were noted between the Baerveldt 250 mm2 and 350 mm2 GDIs, respectively. The size of the GDI may not be associated with surgical outcomes.
authors.affiliation: Dean McGee Eye Institute, Oklahoma City, Oklahoma.
authors.forename: Evan J
authors.initials: EJ
authors.lastname: Allan
authors.affiliation: Dean McGee Eye Institute, Oklahoma City, Oklahoma. Electronic address: Mahmoud-Khaimi@dmei.org.
authors.forename: Mahmoud A
authors.initials: MA
authors.lastname: Khaimi
authors.affiliation: University of Oklahoma Health Sciences Center, College of Medicine, Oklahoma City, Oklahoma.
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Jones
authors.affiliation: Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.
authors.forename: Kai
authors.initials: K
authors.lastname: Ding
authors.affiliation: Dean McGee Eye Institute, Oklahoma City, Oklahoma.
authors.forename: Gregory L
authors.initials: GL
authors.lastname: Skuta
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000503:physiopathology / Q000601:surgery*; D020327:Glaucoma Drainage Implants; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D019919:Prosthesis Implantation; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*