title: Absence of canine papillomavirus sequences in canine mammary tumours.
abstract: Human papillomaviruses (PVs) are found in human breast cancer tissue; however, it remains controversial as to whether these viruses play a role in the aetiology of this tumour. There has been minimal study of whether PVs are found in normal or abnormal mammary glands of animals. The present study investigated whether a PV sequence could be found in the mammary glands of 33 female dogs by rolling circle amplification and polymerase chain reaction. No PV DNA was found in normal or neoplastic canine mammary tissues, suggesting that canine PVs are probably not involved in the pathogenesis of canine mammary neoplasia.
authors.affiliation: School of Veterinary Science, Alfonso X El Sabio University, Madrid, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Sardon
authors.affiliation: School of Veterinary Science, University of Liverpool, Neston, UK.
authors.forename: R
authors.initials: R
authors.lastname: Blundell
authors.affiliation: Dipartimento di Medicina Veterinaria, Università degli Studi di Sassari, Via Vienna 2, Sassari, Italy.
authors.forename: G P
authors.initials: GP
authors.lastname: Burrai
authors.affiliation: Dipartimento di Medicina Veterinaria, Università degli Studi di Sassari, Via Vienna 2, Sassari, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Alberti
authors.affiliation: Dipartimento di Medicina Veterinaria, Università degli Studi di Sassari, Via Vienna 2, Sassari, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Tore
authors.affiliation: Dipartimento di Medicina Veterinaria, Università degli Studi di Sassari, Via Vienna 2, Sassari, Italy.
authors.forename: E Sanna
authors.initials: ES
authors.lastname: Passino
authors.affiliation: Dipartimento di Medicina Veterinaria, Università degli Studi di Sassari, Via Vienna 2, Sassari, Italy. Electronic address: eantuofemo@uniss.it.
authors.forename: E
authors.initials: E
authors.lastname: Antuofermo
mesh_terms: D000818:Animals; D004279:DNA, Viral / Q000032:analysis*; D004283:Dog Diseases / Q000821:virology*; D004285:Dogs; D005260:Female; D015674:Mammary Neoplasms, Animal / Q000821:virology*; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000453:epidemiology / Q000662:veterinary*; D016133:Polymerase Chain Reaction
chemical_list: D004279:DNA, Viral
keywords: dog; mammary tumour; papillomavirus