title: Increasing uptake of live attenuated influenza vaccine among children in the United States, 2008-2014.
abstract: The Advisory Committee on Immunization Practices (ACIP) recommends annual influenza vaccination for all persons in the United States aged ≥6 months. On June 25, 2014, ACIP preferentially recommended live attenuated influenza vaccine (LAIV) for healthy children aged 2-8 years. Little is known about national LAIV uptake. To determine uptake of LAIV relative to inactivated influenza vaccine, we analyzed vaccination records from six immunization information system sentinel sites (approximately 10% of US population). LAIV usage increased over time in all sites. Among children 2-8 years of age vaccinated for influenza, exclusive LAIV usage in the collective sentinel site area increased from 20.1% (2008-09 season) to 38.0% (2013-14). During 2013-14, at least half of vaccinated children received LAIV in Minnesota (50.0%) and North Dakota (55.5%). Increasing LAIV usage suggests formulation acceptability, and this preexisting trend offers a favorable context for implementation of ACIP's preferential recommendation.
authors.affiliation: Immunization Information Systems Support Branch, Immunization Services Division, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address: lrodgers@cdc.gov.
authors.forename: Loren
authors.initials: L
authors.lastname: Rodgers
authors.affiliation: Immunization Information Systems Support Branch, Immunization Services Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Laura J
authors.initials: LJ
authors.lastname: Pabst
authors.affiliation: Epidemiology and Preparedness Branch, Influenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Sandra S
authors.initials: SS
authors.lastname: Chaves
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage*; D007251:Influenza, Human / Q000517:prevention & control*; D008297:Male; D014481:United States; D014611:Vaccination / Q000379:methods / Q000706:statistics & numerical data* / Q000639:trends*; D014613:Vaccines, Attenuated / Q000008:administration & dosage
chemical_list: D007252:Influenza Vaccines; D014613:Vaccines, Attenuated
keywords: Child, Preschool; Immunization information systems; Influenza vaccines; Influenza, Human; Registries; Vaccination; Vaccine coverage