title: Antimicrobial susceptibility profiles of Staphylococcus aureus isolates classified according to their origin in a tertiary hospital in Korea.
abstract: We performed a comprehensive analysis on 3,594 Staphylococcus aureus isolates from routine culture during the last 4 years. The antimicrobial susceptibilities of the isolates were analyzed according to their origin and were compared based on the type of specimens. The proportion of methicillin-resistant Staphylococcus aureus (MRSA) in community-associated (CA), health care-associated, community onset (HACO), and health care-associated (HA) isolates were 33.0%, 54.3%, and 73.3%, respectively. The MRSA rate differed significantly between specimens, with the highest rate from urine in the CA and HACO isolates, whereas the highest rate from the respiratory tract was in the HA isolates. The monitoring of the MRSA rate in CA, HACO, and HA S aureus isolates would be valuable for surveillance. The elevated rates of MRSA in urinary specimens from CA and HCA isolates need to be addressed for infection control.
authors.affiliation: Department of Laboratory Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea. Electronic address: hannasis@kuh.ac.kr.
authors.forename: Hee-Won
authors.initials: HW
authors.lastname: Moon
authors.affiliation: Department of Laboratory Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea.
authors.forename: Hyun Jung
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Laboratory Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea.
authors.forename: Mina
authors.initials: M
authors.lastname: Hur
authors.affiliation: Department of Laboratory Medicine, Konkuk University School of Medicine, Seoul, Republic of Korea.
authors.forename: Yeo-Min
authors.initials: YM
authors.lastname: Yun
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D016106:Methicillin Resistance; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification / Q000502:physiology; D008826:Microbial Sensitivity Tests; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification* / Q000502:physiology
chemical_list: D000890:Anti-Infective Agents
keywords: Antimicrobial susceptibility; Community-associated methicillin-resistant Staphylococcus aureus; Korea; Staphylococcus aureus