title: [Related research on mechanical property of valve membrane in transcatheter bioprosthesis valve based on the chemical modification and cutting technology].
abstract: The aim of this research is to investigate the preparation method of valve membrane in transcatheter bio- prosthetic valve, and to study the effect of chemical modification and cutting technology to tensile property and suture force property of valve membrane. We carried out a series of processes to perform the tests, such as firstly to test the crosslinking degree of valve membrane using ninhydrin method, then to test the tensile property and suture force property by using Instron's biomechanicAl testing equipment, and then to observe the collagen fiber orientation in valve membrane using Instron's biomechanical testing equipment and using field emission scanning electron microscopy. The study indicated that after the chemical modification, the crosslinking degree, tensile strength and suture force strength increasing rate of valve membrane were 93.78% ± 3. 2%, (8.24 ± 0.79) MPa, 102%, respectively. The valve membrane had a better biomechanical property and would be expected to become valve membrane in transcatheter bioprosthesis valve.
authors.forename: Dakai
authors.initials: D
authors.lastname: Chen
authors.forename: Yu
authors.initials: Y
authors.lastname: Li
authors.forename: Qiyi
authors.initials: Q
authors.lastname: Luo
authors.forename: Baolin
authors.initials: B
authors.lastname: Liu
authors.forename: Kangmin
authors.initials: K
authors.lastname: Chen
mesh_terms: D001705:Bioprosthesis; D003094:Collagen / Q000737:chemistry; D006350:Heart Valve Prosthesis; D008855:Microscopy, Electron, Scanning; D013718:Tensile Strength
chemical_list: D003094:Collagen