title: [Pleuro-pericarditis developed under a leflunomide therapy].
abstract: Leflunomide is an immunosuppressant drug used in rheumatoid arthritis and psoriatic arthritis. This product may cause rare but serious interstitial lung disease that appear at the beginning of treatment. This is why leflunomide should be prescribed and monitored in hospital. We present the case of a 71 years old woman who presented a pleuro-pericarditis with an increase of CA 125 during a treatment with leflunomide. This is the second case reported in the literature. The outcome was favorable after discontinuation of leflunomide.
authors.affiliation: Service de pneumologie, hôpital Clavary, BP 53149, 06135 Grasse cedex, France; Centre de soins de suite et de rééducation « La Maison du Mineur », 577, avenue Henri-Giraud, 06141 Vence, France. Electronic address: f.vandenbos@maisondumineur.com.
authors.forename: F
authors.initials: F
authors.lastname: Vandenbos
authors.affiliation: Service de pneumologie, hôpital Clavary, BP 53149, 06135 Grasse cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Figueredo
authors.affiliation: Service de pneumologie, hôpital Clavary, BP 53149, 06135 Grasse cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Tarhini
authors.affiliation: Service de gérontologie et de rhumatologie, hôpital Clavary, BP 53149, 06135 Grasse cedex, France.
authors.forename: J
authors.initials: J
authors.lastname: Ribière
mesh_terms: D000368:Aged; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D005260:Female; D006801:Humans; D007555:Isoxazoles / Q000009:adverse effects*; D000077339:Leflunomide; D010493:Pericarditis / Q000139:chemically induced* / Q000150:complications; D010998:Pleurisy / Q000139:chemically induced* / Q000150:complications
chemical_list: D018501:Antirheumatic Agents; D007555:Isoxazoles; D000077339:Leflunomide
keywords: Leflunomide; Léflunomide; Pericarditis; Pleural effusion; Pleurésie; Psoriatic arthritis; Péricardite; Rhumatisme psoriasique