title: Biocompatible fluorescent organic nanoparticles derived from glucose and polyethylenimine.
abstract: Fluorescent organic nanoparticles (FONs) were facilely prepared from polyethylenimine and glucose at mild reaction condition, and further utilized for cell imaging with various fluorescent wavelengths. The as-prepared PEI-Glu FONs were fully characterized by a series of techniques including 1H NMR spectrum, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, transmission electron microscopy, dynamic light scattering, UV-vis absorption spectrum, and fluorescence spectra. Such FONs were demonstrated with intense fluorescence and high water dispersibility. Biocompatibility evaluation and cell uptake behavior of these FONs were further investigated, which proved excellent biocompatibility and made them promising for cell imaging.
authors.affiliation: Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, PR China. Electronic address: sychyzhang@126.com.
authors.forename: Xiqi
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, PR China; Department of Chemistry/Institute of Polymers, Nanchang University, 999 Xuefu Avenue, Nanchang 330031, PR China.
authors.forename: Xiaoyong
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, PR China.
authors.forename: Bin
authors.initials: B
authors.lastname: Yang
authors.affiliation: Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, PR China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, PR China.
authors.forename: Qiaomei
authors.initials: Q
authors.lastname: Chen
authors.affiliation: Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, PR China. Electronic address: weiyen@tsinghua.edu.cn.
authors.forename: Yen
authors.initials: Y
authors.lastname: Wei
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D005453:Fluorescence; D005947:Glucose / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D011094:Polyethyleneimine / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D011094:Polyethyleneimine; D005947:Glucose
keywords: Biocompatibility; Cell imaging; Fluorescent organic nanoparticles; Glucose; Polyethylenimine