title: Deriving blood stem cells from pluripotent stem cells for research and therapy.
abstract: Embryonic stem cells and induced pluripotent stem cells offer promise for research and treatment of hematologic diseases. While broad clinical application in humans is still a distant prospect, there are promising near-term applications in transfusion of platelets and red blood cells.
authors.affiliation: Stem Cell Transplantation Program, Children's Hospital and Dana-Farber Cancer Institute, USA; Harvard Medical School, USA; Howard Hughes Medical Institute, USA. Electronic address: George.Daley@childrens.harvard.edu.
authors.forename: George Q
authors.initials: GQ
authors.lastname: Daley
mesh_terms: D000818:Animals; D053595:Embryonic Stem Cells / Q000166:cytology / Q000378:metabolism / Q000637:transplantation; D017707:Erythrocyte Transfusion; D006402:Hematologic Diseases / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology / Q000378:metabolism* / Q000637:transplantation*; D017713:Platelet Transfusion
keywords: hematopoietic stem cells (HSCs); induced pluripotent; stem cell models; stem cells; transcription factors