title: Magnetic resonance colonography with a limited bowel preparation and automated carbon dioxide insufflation in comparison to conventional colonoscopy: patient burden and preferences.
abstract: OBJECTIVE
  To evaluate patient burden and preferences for MR colonography with a limited bowel preparation and automated carbon dioxide insufflation in comparison to conventional colonoscopy.
  
  
  METHODS
  Symptomatic patients were consecutively recruited to undergo MR colonography with automated carbon dioxide insufflation and a limited bowel preparation followed within four weeks by colonoscopy with a standard bowel cleansing preparation. Four questionnaires regarding burden (on a five-point scale) and preferences (on a seven-point scale) were addressed after MR colonography and colonoscopy and five weeks after colonoscopy.
  
  
  RESULTS
  Ninety-nine patients (47 men, 52 women; mean age 62.3, SD 8.7) were included. None of the patients experienced severe or extreme burden from the MR colonography bowel preparation compared to 31.5% of the patients for the colonoscopy bowel preparation. Colonoscopy was rated more burdensome (25.6% severe or extreme burden) compared to MR colonography (5.2% severe or extreme burden) (P<0.0001). When discarding the bowel preparations, the examinations were rated equally burdensome (P=0.35). The majority of patients (61.4%) preferred MR colonography compared to colonoscopy (29.5%) immediately after the examinations and five weeks later (57.0% versus 39.5%).
  
  
  CONCLUSIONS
  MR colonography with a limited bowel preparation and automated carbon dioxide insufflation demonstrated less burden compared to colonoscopy. The majority of patients preferred MR colonography over colonoscopy.
authors.affiliation: Department of Radiology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands. Electronic address: m.p.vanderpaardt@amc.uva.nl.
authors.forename: M P
authors.initials: MP
authors.lastname: van der Paardt
authors.affiliation: Department of Radiology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands. Electronic address: t.n.boellaard@amc.uva.nl.
authors.forename: T N
authors.initials: TN
authors.lastname: Boellaard
authors.affiliation: Department of Radiology, Medisch Centrum Haaglanden, Den Haag, The Netherlands. Electronic address: fmzijta@yahoo.com.
authors.forename: F M
authors.initials: FM
authors.lastname: Zijta
authors.affiliation: Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands. Electronic address: l.c.baak@olvg.nl.
authors.forename: L C
authors.initials: LC
authors.lastname: Baak
authors.affiliation: Department of Gastroenterology and Hepatology, Slotervaartziekenhuis, Amsterdam, The Netherlands. Electronic address: actm.depla@slz.nl.
authors.forename: A C T M
authors.initials: ACTM
authors.lastname: Depla
authors.affiliation: Department of Gastroenterology and Hepatology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands. Electronic address: e.dekker@amc.uva.nl.
authors.forename: E
authors.initials: E
authors.lastname: Dekker
authors.affiliation: Department of Radiology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands. Electronic address: a.j.nederveen@amc.uva.nl.
authors.forename: A J
authors.initials: AJ
authors.lastname: Nederveen
authors.affiliation: Department of Radiology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands. Electronic address: s.bipat@amc.uva.nl.
authors.forename: S
authors.initials: S
authors.lastname: Bipat
authors.affiliation: Department of Radiology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands. Electronic address: j.stoker@amc.uva.nl.
authors.forename: J
authors.initials: J
authors.lastname: Stoker
mesh_terms: D000328:Adult; D000368:Aged; D002245:Carbon Dioxide; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000473:pathology*; D017281:Cost of Illness; D005260:Female; D006801:Humans; D007327:Insufflation / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D057240:Patient Preference / Q000706:statistics & numerical data; D011446:Prospective Studies; D011795:Surveys and Questionnaires
chemical_list: D002245:Carbon Dioxide
keywords: Carbon dioxide; Colon; Insufflation; Iodine; Magnetic resonance imaging; Patient preference