title: DXA-based variables and osteoporotic fractures in Lebanese postmenopausal women.
abstract: BACKGROUND
  The aim of this study was to assess DXA-based variables (bone mineral density, bone mineral apparent density, compressive strength index of the femoral neck and trabecular bone score) in Lebanese postmenopausal women having presented a previous fracture.
  
  
  METHODS
  One thousand Lebanese postmenopausal women between 45 and 89 years participated in this study. The women were recruited by advertisements offering bone mineral density measurements at a reduced cost. Subjects with previous history of radiotherapy or chemotherapy were excluded. Informed written consent was obtained from all the participants.
  
  
  RESULTS
  Femoral neck compressive strength index (FN CSI) was significantly (P<0.001) associated with the presence of fracture using a simple logistic regression (odds ratio=0.51 [0.385-0.653]). When a multivariate logistic regression analysis was performed with the presence of fracture as a dependent variable and each of age, FN BMD and FN CSI as independent variables, only FN BMD (P=0.005) and FN CSI (P=0.004) were found to be associated with the presence of fracture.
  
  
  CONCLUSIONS
  This study suggests that FN CSI is associated with history of osteoporotic fractures in postmenopausal women. The use of FN CSI in clinical practice may help to identify patients with high risk of fracture.
  
  
  METHODS
  Epidemiological study, level IV.
authors.affiliation: Department of Physical Education, Faculty of Arts and Social Sciences, University of Balamand, El-Koura, Lebanon.
authors.forename: M-L
authors.initials: ML
authors.lastname: Ayoub
authors.affiliation: Musculoskeletal Department, Bellevue Medical Center, Faculty of Medicine of Saint-Joseph University, Mansourieh, Lebanon.
authors.forename: G
authors.initials: G
authors.lastname: Maalouf
authors.affiliation: Musculoskeletal Department, Bellevue Medical Center, Faculty of Medicine of Saint-Joseph University, Mansourieh, Lebanon.
authors.forename: F
authors.initials: F
authors.lastname: Bachour
authors.affiliation: Musculoskeletal Department, Bellevue Medical Center, Faculty of Medicine of Saint-Joseph University, Mansourieh, Lebanon.
authors.forename: A
authors.initials: A
authors.lastname: Barakat
authors.affiliation: Department of Rheumatology, Roger Salengro Hospital, CHU de Lille, 59037 Lille cedex, France; EA4490, 62327 Boulogne-sur-Mer cedex, France.
authors.forename: B
authors.initials: B
authors.lastname: Cortet
authors.affiliation: Department of Rheumatology, Roger Salengro Hospital, CHU de Lille, 59037 Lille cedex, France; EA4490, 62327 Boulogne-sur-Mer cedex, France.
authors.forename: I
authors.initials: I
authors.lastname: Legroux-Gérot
authors.affiliation: Départment of STAPS, URePSSS-EA 4110/EA448, ULCO, 59383 Dunkerque cedex 01, France.
authors.forename: G
authors.initials: G
authors.lastname: Zunquin
authors.affiliation: Départment of STAPS, URePSSS-EA 4110/EA448, ULCO, 59383 Dunkerque cedex 01, France.
authors.forename: D
authors.initials: D
authors.lastname: Theunynck
authors.affiliation: Department of Orthopedic Surgery and Traumatology, Saint-Georges University Medical Center, University of Balamand, P.O. Box 166378, Achrafieh, 1100 2807 Beirut, Lebanon.
authors.forename: A
authors.initials: A
authors.lastname: Nehme
authors.affiliation: Department of Physical Education, Faculty of Arts and Social Sciences, University of Balamand, El-Koura, Lebanon. Electronic address: rawadelhage21@hotmail.com.
authors.forename: R
authors.initials: R
authors.lastname: El Hage
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods*; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D005260:Female; D005272:Femur Neck / Q000000981:diagnostic imaging*; D006801:Humans; D007861:Lebanon / Q000453:epidemiology; D016015:Logistic Models; D008875:Middle Aged; D016017:Odds Ratio; D058866:Osteoporotic Fractures / Q000000981:diagnostic imaging / Q000453:epidemiology*; D017698:Postmenopause
keywords: Compressive Strength Index; Dual X-ray absorptiometry; Femur; Fracture risk; Menopause