title: Detection of the new emerging rabbit haemorrhagic disease type 2 virus (RHDV2) in Sicily from rabbit (Oryctolagus cuniculus) and Italian hare (Lepus corsicanus).
abstract: Rabbit haemorrhagic disease virus (RHDV), a member of the genus Lagovirus, causes rabbit haemorrhagic disease (RHD), a fatal hepatitis of rabbits, not previously reported in hares. Recently, a new RHDV-related virus emerged, called RHDV2. This lagovirus can cause RHD in rabbits and disease and mortality in Lepus capensis (Cape hare). Here we describe a case of RHDV2 infection in another hare species, Lepus corsicanus, during a concurrent RHD outbreak in a group of wild rabbits. The same RHDV2 strain infected rabbits and a hare, also causing a RHD-like syndrome in the latter. Our findings confirmed the capability of RHDV2 to infect hosts other than rabbits and improve the knowledge about the epidemiology and the host range of this new lagovirus.
authors.affiliation: Department of Veterinary Medicine, the University of Bari "Aldo Moro", S.P. per Casamassima, km 3, Valenzano, BA 70010, Italy. Electronic address: antonio.camarda@uniba.it.
authors.forename: A
authors.initials: A
authors.lastname: Camarda
authors.affiliation: Department of Veterinary Medicine, the University of Bari "Aldo Moro", S.P. per Casamassima, km 3, Valenzano, BA 70010, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Pugliese
authors.affiliation: Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini" - OIE Reference Laboratory for Rabbit Haemorrhagic Disease, Via A. Bianchi 7/9, Brescia 25124, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Cavadini
authors.affiliation: Department of Veterinary Medicine, the University of Bari "Aldo Moro", S.P. per Casamassima, km 3, Valenzano, BA 70010, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Circella
authors.affiliation: Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini" - OIE Reference Laboratory for Rabbit Haemorrhagic Disease, Via A. Bianchi 7/9, Brescia 25124, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Capucci
authors.affiliation: Department of Veterinary Medicine, the University of Bari "Aldo Moro", S.P. per Casamassima, km 3, Valenzano, BA 70010, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Caroli
authors.affiliation: Department of Veterinary Medicine, the University of Bari "Aldo Moro", S.P. per Casamassima, km 3, Valenzano, BA 70010, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Legretto
authors.affiliation: Regional Park of Gallipoli Cognato, Piccole Dolomiti Lucane, Matera, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Mallia
authors.affiliation: Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini" - OIE Reference Laboratory for Rabbit Haemorrhagic Disease, Via A. Bianchi 7/9, Brescia 25124, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Lavazza
mesh_terms: D000818:Animals; D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D016000:Cluster Analysis; D021821:Communicable Diseases, Emerging / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D017931:DNA Primers / Q000235:genetics; D004196:Disease Outbreaks / Q000662:veterinary*; D034621:Hares / Q000821:virology*; D017929:Hemorrhagic Disease Virus, Rabbit / Q000235:genetics / Q000302:isolation & purification*; D008099:Liver / Q000821:virology; D008168:Lung / Q000473:pathology; D008854:Microscopy, Electron; D010802:Phylogeny; D011817:Rabbits / Q000821:virology*; D012802:Sicily / Q000453:epidemiology; D013045:Species Specificity; D014132:Trachea / Q000473:pathology
chemical_list: D017931:DNA Primers
keywords: Host susceptibility; Lagovirus RHDV2; Lepus corsicanus; Oryctolagus cuniculus; Rabbit haemorrhagic disease