title: [The risk-reducing mastectomy: unnecessary hysteria or life-saving prophylaxis?].
abstract: The prophylactic (risk-reducing) mastectomy is a world-wide recognized method for specifically treating the increased breast cancer risk in patients showing a BRCA1 and/or BRCA2 mutation as well as other patient groups at increased breast cancer risk. This option should be offered to all patients having the pertinent risk profile. Breast reconstruction is an integral part of the risk-reducing mastectomy procedure and all possible methods of breast reconstruction, especially autologous tissue reconstruction should be offered to all patients having a medical indication and desiring this surgical treatment. These patients are best managed in certified Breast Care Centres where the different medical and surgical specialists can address interdisciplinary all aspects of genetic counselling, preoperative counselling, mastectomy and reconstructive techniques as well as the necessary postoperative surveillance.
authors.affiliation: Universität Bern, Departement Klinische Forschung, Plastische Chirurgie, Inselspital, Bern.
authors.forename: Radu
authors.initials: R
authors.lastname: Olariu
authors.affiliation: Universität Bern, Departement Klinische Forschung, Plastische Chirurgie, Inselspital, Bern.
authors.forename: Maziar
authors.initials: M
authors.lastname: Shafighi
authors.affiliation: Universität Bern, Departement Klinische Forschung, Plastische Chirurgie, Inselspital, Bern.
authors.forename: Mihai A
authors.initials: MA
authors.lastname: Constantinescu
mesh_terms: D001943:Breast Neoplasms / Q000401:mortality* / Q000601:surgery*; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000379:methods* / Q000706:statistics & numerical data; D018579:Patient Selection; D011322:Primary Prevention / Q000379:methods*; D065286:Prophylactic Surgical Procedures / Q000379:methods* / Q000706:statistics & numerical data; D018570:Risk Assessment; D016896:Treatment Outcome; D019564:Unnecessary Procedures