title: [Multiple epimutations in imprinted genes in the human genome and congenital disorders].
abstract: The current knowledge on multiple epimutations in imprinted genes and their impact on the disturbances of human prenatal development and the emergence of hereditary diseases are reviewed and analyzed. Genetic mechanisms regulating the epigenetic state of imprinted loci in the human genome are discussed.
authors.forename: M V
authors.initials: MV
authors.lastname: Lepshin
authors.forename: E A
authors.initials: EA
authors.lastname: Sazhenova
authors.forename: I N
authors.initials: IN
authors.lastname: Lebedev
mesh_terms: D025063:Chromosome Disorders / Q000235:genetics; D044127:Epigenesis, Genetic; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D015894:Genome, Human; D018392:Genomic Imprinting; D006801:Humans; D009154:Mutation