title: [Scurvy, an old disease still in the news: two case reports].
abstract: Scurvy is the clinical manifestation of a deficiency in vitamin C, which is present in fresh fruits and vegetables. It is historically linked to the era of great maritime expeditions. Manifestations are misleading in children, in contrast with adults: bone disease and hemorrhagic syndrome are the earliest and most frequent manifestations due to a collagen biosynthesis defect. Scurvy is an old, potentially fatal disease but is easily curable with ascorbic acid. It can be prevented with vitamin C treatment in pediatric populations with unusual eating habits. We describe two cases of pediatric scurvy in two 7-year-old boys who had dietary restrictions stemming from developmental disorders.
authors.affiliation: Unité de médecine infantile, CHU de la Timone Enfants, AP-HM, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France; Service de pédiatrie générale, CHG Henri-Duffaut, 305, rue Raoul-Follereau 84902 Avignon cedex 9, France.
authors.forename: S
authors.initials: S
authors.lastname: Pailhous
authors.affiliation: Service de pédiatrie générale, CHG Henri-Duffaut, 305, rue Raoul-Follereau 84902 Avignon cedex 9, France.
authors.forename: S
authors.initials: S
authors.lastname: Lamoureux
authors.affiliation: Service de neurologie pédiatrique, CHU de la Timone Enfants, AP-HM, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France.
authors.forename: E
authors.initials: E
authors.lastname: Caietta
authors.affiliation: Unité de médecine infantile, CHU de la Timone Enfants, AP-HM, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France.
authors.forename: E
authors.initials: E
authors.lastname: Bosdure
authors.affiliation: Service d'hématologie pédiatrique, CHU de la Timone Enfants, AP-HM, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France.
authors.forename: H
authors.initials: H
authors.lastname: Chambost
authors.affiliation: Service de neurologie pédiatrique, CHU de la Timone Enfants, AP-HM, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France.
authors.forename: B
authors.initials: B
authors.lastname: Chabrol
authors.affiliation: Unité de médecine infantile, CHU de la Timone Enfants, AP-HM, 264, rue Saint-Pierre, 13385 Marseille cedex 5, France. Electronic address: violane.bresson@ap-hm.fr.
authors.forename: V
authors.initials: V
authors.lastname: Bresson
mesh_terms: D002648:Child; D015362:Child Nutrition Disorders / Q000150:complications; D042963:Electron Transport Complex II / Q000235:genetics; D005638:Fruit; D006801:Humans; D008297:Male; D028361:Mitochondrial Diseases / Q000150:complications; D012614:Scurvy / Q000175:diagnosis*; D014675:Vegetables; D018980:Williams Syndrome / Q000150:complications
chemical_list: D042963:Electron Transport Complex II