title: Current knowledge about and recommendations for ocular methicillin-resistant Staphylococcus aureus.
abstract: Staphylococcus aureus is the most important and common pathogen that infects patients following cataract surgery, laser in situ keratomileusis, and photorefractive keratectomy. It is reported to be the second most common pathogen causing bacterial keratitis around the world. Of special concern are increasing reports of postoperative methicillin-resistant S aureus (MRSA) infection. For example, MRSA wound infections have been reported with clear corneal phacoemulsification wounds, penetrating keratoplasty, lamellar keratoplasty, and following ex vivo epithelial transplantation associated with amniotic membrane grafts. These and other data suggest that MRSA has become increasingly prevalent worldwide. In this article, we review the current medical literature and describe the current challenge of ocular MRSA infections. Recommendations are made based on an evidence-based review to identify, treat, and possibly reduce the overall problem of this organism.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors.forename: Francis S
authors.initials: FS
authors.lastname: Mah
authors.forename: Richard
authors.initials: R
authors.lastname: Davidson
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Holland
authors.forename: John
authors.initials: J
authors.lastname: Hovanesian
authors.forename: Thomas
authors.initials: T
authors.lastname: John
authors.forename: John
authors.initials: J
authors.lastname: Kanellopoulos
authors.forename: Neda
authors.initials: N
authors.lastname: Shamie
authors.forename: Christopher
authors.initials: C
authors.lastname: Starr
authors.forename: David
authors.initials: D
authors.lastname: Vroman
authors.forename: Terry
authors.initials: T
authors.lastname: Kim
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003320:Corneal Ulcer / Q000175:diagnosis / Q000382:microbiology* / Q000517:prevention & control; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000517:prevention & control; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000382:microbiology* / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents