title: Dissecting intraflagellar transport, one molecule at a time.
abstract: Intraflagellar transport (IFT) is required for proper function of cilia, although many of the mechanistic details underlying this process are obscure. Two studies in this issue of Developmental Cell illuminate key functions of one IFT protein, IFT27, and offer clues into how IFT cargo is selected and transported.
authors.affiliation: Center for Human Disease Modeling, Duke University Medical Center, Durham, NC 27701, USA.
authors.forename: Erica E
authors.initials: EE
authors.lastname: Davis
authors.affiliation: Center for Human Disease Modeling, Duke University Medical Center, Durham, NC 27701, USA. Electronic address: katsanis@cellbio.duke.edu.
authors.forename: Nicholas
authors.initials: N
authors.lastname: Katsanis
mesh_terms: D020727:ADP-Ribosylation Factors / Q000378:metabolism*; D000818:Animals; D002923:Cilia / Q000378:metabolism*; D015398:Signal Transduction; D020691:rab GTP-Binding Proteins / Q000378:metabolism*
chemical_list: C000595889:intraflagellar transport 27 protein, mouse; D020727:ADP-Ribosylation Factors; C122027:Arl6 protein, mouse; D020691:rab GTP-Binding Proteins