title: Depression and coping strategies of Chinese women undergoing in-vitro fertilization.
abstract: OBJECTIVE
  To explore the relationship between coping strategies and depression, and the risk factors of depression among Chinese women in infertile couples undergoing in-vitro fertilization (IVF).
  
  
  METHODS
  Two hundred and eighty-eight women undergoing IVF completed the Center for Epidemiologic Studies Short Depression Scale and the Brief COPE Inventory. Demographic data were collected, hormone levels were tested and oocyte numbers were counted.
  
  
  RESULTS
  The incidence of depression was 22.6%. The prevalence of depression was higher among women who had been married for >8 years, women who had been infertile for >6 years and women with a family income ≤3000 CNY/month. High basal follicle-stimulating hormone, oocyte number and denial score were associated with greater risk of depression. High oestradiol (basal and peak), and substance use and humour scores were associated with lower risk of depression.
  
  
  CONCLUSIONS
  Many women in infertile couples undergoing IVF have depression. Preventive interventions should be provided for women with risk factors of depression, such as long duration of marriage, long duration of infertility, low monthly family income, high basal follicle-stimulating hormone, low serum oestradiol, high oocyte number, and use of denial as a coping strategy.
authors.affiliation: Reproductive Medical Centre, Renmin Hospital of Wuhan University, Wuhan, China.
authors.forename: Gengxiang
authors.initials: G
authors.lastname: Wu
authors.affiliation: Reproductive Medical Centre, Renmin Hospital of Wuhan University, Wuhan, China.
authors.forename: Tailang
authors.initials: T
authors.lastname: Yin
authors.affiliation: Reproductive Medical Centre, Renmin Hospital of Wuhan University, Wuhan, China. Electronic address: dryangqing@126.com.
authors.forename: Jing
authors.initials: J
authors.lastname: Yang
authors.affiliation: Reproductive Medical Centre, Renmin Hospital of Wuhan University, Wuhan, China.
authors.forename: Wangming
authors.initials: W
authors.lastname: Xu
authors.affiliation: Reproductive Medical Centre, Renmin Hospital of Wuhan University, Wuhan, China.
authors.forename: Yujie
authors.initials: Y
authors.lastname: Zou
authors.affiliation: Reproductive Medical Centre, Renmin Hospital of Wuhan University, Wuhan, China.
authors.forename: Yaqin
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Reproductive Medical Centre, Renmin Hospital of Wuhan University, Wuhan, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wen
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D002681:China; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000523:psychology; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D015994:Incidence; D007247:Infertility, Female / Q000523:psychology* / Q000628:therapy; D016015:Logistic Models; D015995:Prevalence; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors
keywords: Coping strategies; Depression; Embryo transfer; In-vitro fertilization; Infertile