title: ALK and ROS1 non-small-cell lung cancer: two molecular subgroups sensitive to targeted therapy.
authors.affiliation: Cancer Biology and Precision Medicine Program, Catalan Institute of Oncology, Badalona, Barcelona, Spain; Germans Trias I Pujol Health Science Research Institute and Hospital, Campus Can Ruti, Badalona, Barcelona 08916, Spain; Molecular Oncology Research Foundation, Barcelona, Spain. Electronic address: rrosell@iconcologia.net.
authors.forename: Rafael
authors.initials: R
authors.lastname: Rosell
authors.affiliation: Germans Trias I Pujol Health Science Research Institute and Hospital, Campus Can Ruti, Badalona, Barcelona 08916, Spain.
authors.forename: Niki
authors.initials: N
authors.lastname: Karachaliou
authors.affiliation: Center for Integrated Oncology Köln Bonn, Cologne, Germany; Lung Cancer Group Cologne, Department I for Internal Medicine, University Hospital of Cologne, Cologne, Germany.
authors.forename: Juergen
authors.initials: J
authors.lastname: Wolf
authors.affiliation: Family Comprehensive Cancer Center, Department of Medicine, Division of Hematology/Oncology; University of California Irvine School of Medicine, CA, USA.
authors.forename: Sai-Hong Ignatius
authors.initials: SH
authors.lastname: Ou
mesh_terms: D000077548:Anaplastic Lymphoma Kinase; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002289:Carcinoma, Non-Small-Cell Lung / Q000235:genetics* / Q000628:therapy; D002986:Clinical Trials as Topic; D019008:Drug Resistance, Neoplasm / Q000235:genetics; D015321:Gene Rearrangement; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics* / Q000628:therapy; D058990:Molecular Targeted Therapy / Q000379:methods*; D009154:Mutation / Q000235:genetics; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics*
chemical_list: D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors; D011518:Proto-Oncogene Proteins; C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D011505:Protein-Tyrosine Kinases; C062333:ROS1 protein, human; D020794:Receptor Protein-Tyrosine Kinases