title: Mitofusin 2 ameliorates aortic remodeling by suppressing ras/raf/ERK pathway and regulating mitochondrial function in vascular smooth muscle cells.
authors.affiliation: Department of Hypertension, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing 100029, PR China.
authors.forename: Zuoguang
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Hypertension, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing 100029, PR China.
authors.forename: Qiuli
authors.initials: Q
authors.lastname: Niu
authors.affiliation: Institute of Westnorth Plateau Biology, Chinese Academy of Sciences, 650032, PR China.
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: Peng
authors.affiliation: Department of Hypertension, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing 100029, PR China.
authors.forename: Mei
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Hypertension, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing 100029, PR China.
authors.forename: Ya
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Hypertension, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing 100029, PR China.
authors.forename: Jielin
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Hypertension, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing 100029, PR China.
authors.forename: Shaojun
authors.initials: S
authors.lastname: Wen
authors.affiliation: Department of Hypertension, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, Blood Vessel Diseases, Beijing 100029, PR China. Electronic address: wzg70@yahoo.com.
authors.forename: Yongxiang
authors.initials: Y
authors.lastname: Wei
mesh_terms: D000818:Animals; D001011:Aorta / Q000378:metabolism; D020558:GTP Phosphohydrolases; D011905:Genes, ras / Q000502:physiology*; D020935:MAP Kinase Signaling System / Q000502:physiology*; D008565:Membrane Proteins / Q000096:biosynthesis*; D008928:Mitochondria / Q000502:physiology*; D024101:Mitochondrial Proteins / Q000096:biosynthesis*; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D032389:Myocytes, Smooth Muscle / Q000378:metabolism; D011897:Random Allocation; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D066253:Vascular Remodeling / Q000502:physiology*; D048490:raf Kinases / Q000502:physiology*
chemical_list: D008565:Membrane Proteins; D024101:Mitochondrial Proteins; D048490:raf Kinases; D020558:GTP Phosphohydrolases; C489710:Mfn2 protein, rat
keywords: Antihypertensive treatment; Aortic remodeling; Mitochondria; Mitofusin 2; Oxidative stress