title: FDA perspective on sofosbuvir therapy for patients with chronic hepatitis C virus genotype 1 infection who did not respond to treatment with pegylated interferon and ribavirin.
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Poonam
authors.initials: P
authors.lastname: Mishra
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Jeffry
authors.initials: J
authors.lastname: Florian
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Karen
authors.initials: K
authors.lastname: Qi
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Wen
authors.initials: W
authors.lastname: Zeng
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Lisa K
authors.initials: LK
authors.lastname: Naeger
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Eric
authors.initials: E
authors.lastname: Donaldson
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Sarah
authors.initials: S
authors.lastname: Connelly
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Jules
authors.initials: J
authors.lastname: O'Rear
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Dionne
authors.initials: D
authors.lastname: Price
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Murray
authors.affiliation: US Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Debra
authors.initials: D
authors.lastname: Birnkrant
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D017277:Drug Approval; D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D000069474:Sofosbuvir; D014542:Uridine Monophosphate / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000998:Antiviral Agents; D014542:Uridine Monophosphate; D000069474:Sofosbuvir