title: The essential of 2012 results from the French Renal Epidemiology and Information Network (REIN) ESRD registry.
abstract: The French Renal Epidemiology and Information Network (REIN) registry began in 2002 to provide a tool for public health decision support, evaluation and research related to renal replacement therapies (RRT) for end-stage renal disease (ESRD). It is relying on a network of nephrologists, epidemiologists, patients and public health representatives. Continuous registration covers all dialysis and transplanted patients. In 2012, in France, 10,048 patients started a RRT (154 per million inhabitants). Elders provided majority of new patients (median age at RRT start: 70 years old). New patients had a high and age increasing rate of comorbidities, especially diabetes (42% of the new patients) and cardiovascular comorbidities (>50% of the new patients). Like previous years, incidence is stabilized. On December 31, 2012, 73,491 patients were receiving a RRT in France (1127 per million inhabitants, 56% on dialysis and 44% living with a functional renal transplant). More than 50% of patients were undergoing in-center hemodialysis with significant variations among regions. An increase in medical satellite unit hemodialysis but a decrease in self-care unit hemodialysis rates were noticed across the time, whereas peritoneal dialysis remained stable at 7%. Five years after starting RRT, the overall survival rate was 51% but only 16% among patients over 85 years. Mortality rate was highly dependent on treatment and age; transplanted patients aged 60-69 had a 27/1000 patients-year mortality rate versus 133 for a dialysis patient. Patients who started dialysis had a probability of first wait-listing of 4.8% at the start of dialysis (pre-emptive registrations) and 27% at 72 months. Whatever their diabetes status was, patients older than 60 had poor access to the waiting list. Seventeen percent of the patients received a first renal transplant within 15.4 month median time; 3% had received a pre-emptive graft. Ten years after the start of the French ESRD registry, this report provides a comprehensive and nation-wide overview of dialysis and transplantation cares in France, including overseas.
authors.affiliation: Coordination nationale, agence de la biomédecine, 1, avenue du Stade-de-France, 93212 Saint-Denis-la-Plaine cedex, France. Electronic address: mathilde.lassalle@biomedecine.fr.
authors.forename: Mathilde
authors.initials: M
authors.lastname: Lassalle
authors.affiliation: Coordination régionale Lorraine, CHU de Nancy, Nancy, France.
authors.forename: Carole
authors.initials: C
authors.lastname: Ayav
authors.affiliation: Coordination régionale Lorraine, CHU de Nancy, Nancy, France.
authors.forename: Luc
authors.initials: L
authors.lastname: Frimat
authors.affiliation: Coordination nationale, agence de la biomédecine, 1, avenue du Stade-de-France, 93212 Saint-Denis-la-Plaine cedex, France.
authors.forename: Christian
authors.initials: C
authors.lastname: Jacquelinet
authors.affiliation: Coordination nationale, agence de la biomédecine, 1, avenue du Stade-de-France, 93212 Saint-Denis-la-Plaine cedex, France.
authors.forename: Cécile
authors.initials: C
authors.lastname: Couchoud
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007676:Kidney Failure, Chronic / Q000453:epidemiology* / Q000628:therapy; D016030:Kidney Transplantation / Q000706:statistics & numerical data*; D008875:Middle Aged; D015995:Prevalence; D012042:Registries; D006435:Renal Dialysis / Q000706:statistics & numerical data*; D066027:Transplant Recipients; D055815:Young Adult
keywords: ESRD; Epidemiology; Incidence; Prevalence; Survival; Transplantation