title: Analysis of incidence and genetic predisposition of preauricular sinus.
abstract: OBJECTIVE
  To evaluate the incidence of preauricular sinus, the association between preauricular sinus of a parent and their children, and the odds of hearing impairments in patients with preauricular sinus.
  
  
  METHODS
  A cross-sectional study was performed using data from the Korea National Health and Nutrition Examination Survey. We evaluated data from 23,533 subjects who were interviewed between 2010 and 2012.
  
  
  RESULTS
  The incidence of unilateral preauricular sinus was 1.3% and that of bilateral preauricular sinus was 0.3%. Female gender was statistically associated with preauricular sinus (adjusted odd ratio, AOR=1.401). There was no statistical difference between right- and left-sided preauricular sinus. There was an association between parents and their children for bilateral preauricular sinus (AOR of father's bilateral preauricular sinus=35.711; AOR of mother's bilateral preauricular sinus=7.683), but there was no association found for unilateral preauricular sinus. There was no link found between hearing impairment and preauricular sinus.
  
  
  CONCLUSIONS
  This large population-based study provides reliable information about the incidence of preauricular sinus, the association between preauricular sinus in parents and their children, and the lack of an association with hearing impairment; these results can help clinicians in the management of their patients.
authors.affiliation: Department of Otorhinolaryngology-Head & Neck Surgery, Thyroid/Head & Neck Cancer Center of the Dongnam Institute of Radiological & Medical Sciences (DIRAMS), Busan, Republic of Korea.
authors.forename: Soo-Youn
authors.initials: SY
authors.lastname: An
authors.affiliation: Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea. Electronic address: pupen@naver.com.
authors.forename: Hyo Geun
authors.initials: HG
authors.lastname: Choi
authors.affiliation: Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
authors.forename: Joong Seob
authors.initials: JS
authors.lastname: Lee
authors.affiliation: Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
authors.forename: Ji Hee
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
authors.forename: Seung Woo
authors.initials: SW
authors.lastname: Yoo
authors.affiliation: Department of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, Anyang, Republic of Korea.
authors.forename: Bumjung
authors.initials: B
authors.lastname: Park
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D019465:Craniofacial Abnormalities / Q000150:complications / Q000453:epidemiology* / Q000235:genetics*; D003430:Cross-Sectional Studies; D005260:Female; D020022:Genetic Predisposition to Disease; D034381:Hearing Loss / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D010290:Parents; D010375:Pedigree; D056910:Republic of Korea / Q000453:epidemiology; D012737:Sex Factors; D055815:Young Adult
keywords: Auricle; Ear; Etiology; Fistula; Prevalence; Sinus