title: Feasibility of ultra-low radiation dose reduction for renal stone CT using model-based iterative reconstruction: prospective pilot study.
abstract: OBJECTIVE
  To compare dose, reader assessments, and noise between ultra-low-dose (ULD) and low-dose (LD) renal stone computed tomography (CT) using multiple reconstruction methods.
  
  
  METHODS
  Prospective study of 19 patients having noncontrast LD and ULD renal stone CT reconstructed using filtered back projection, adaptive statistical iterative reconstruction (ASIR), and model-based iterative reconstruction (MBIR). Dose, noise measurements, and subjective image assessments were recorded.
  
  
  RESULTS
  ULD volume CT dose index was 61% less. Noise was 50% less with ULD MBIR than with LD ASIR (P<.001); no other significant differences existed.
  
  
  CONCLUSIONS
  ULD MBIR is comparable to our standard of care, LD ASIR, with 61% lower dose and 50% less noise.
authors.affiliation: Department of Radiology, Mayo Clinic Hospital, Phoenix, AZ. Electronic address: skriegshauser@mayo.edu.
authors.forename: J
authors.initials: J
authors.lastname: Scott Kriegshauser
authors.affiliation: Department of Radiology, Mayo Clinic Hospital, Phoenix, AZ.
authors.forename: Sailen G
authors.initials: SG
authors.lastname: Naidu
authors.affiliation: Department of Radiology, Mayo Clinic Hospital, Phoenix, AZ.
authors.forename: Robert G
authors.initials: RG
authors.lastname: Paden
authors.affiliation: Department of Industrial Engineering, Arizona State University, Tempe, AZ.
authors.forename: Miao
authors.initials: M
authors.lastname: He
authors.affiliation: Division of Health Sciences Research, Mayo Clinic, Scottsdale, AZ.
authors.forename: Qing
authors.initials: Q
authors.lastname: Wu
authors.affiliation: Department of Radiology, Mayo Clinic, Scottsdale, AZ.
authors.forename: Amy K
authors.initials: AK
authors.lastname: Hara
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007669:Kidney Calculi / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011446:Prospective Studies; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*
keywords: Computed tomography; Model-based iterative reconstruction (MBIR); Radiation dose; Renal stones