title: Nitrous oxide for pain management of first trimester surgical abortion -- a randomized controlled pilot study.
abstract: OBJECTIVE
  The objective was to determine feasibility of a study comparing mean pain scores between women randomized to nitrous oxide/oxygen (NO) versus oxygen+oral analgesics for trimester surgical abortion.
  
  
  METHODS
  Pilot randomized controlled trial comparing NO (n=10) versus oxygen+oral analgesics (n=10). Feasibility of subject recruitment, and pain and satisfaction scores on a visual analog scale were evaluated.
  
  
  RESULTS
  Fifty-seven percent of eligible women participated. Mean pain scores were similar between groups, and mean satisfaction scores were higher for the NO group (77.5 vs. 46.7, P=.048).
  
  
  CONCLUSIONS
  The majority of eligible women agreed to participate in this study evaluating an uncommon pain control intervention.
authors.affiliation: University of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico. Electronic address: RHSingh@salud.unm.edu.
authors.forename: Rameet H
authors.initials: RH
authors.lastname: Singh
authors.affiliation: University of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico.
authors.forename: Eve
authors.initials: E
authors.lastname: Espey
authors.affiliation: University of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico.
authors.forename: Shannon
authors.initials: S
authors.lastname: Carr
authors.affiliation: University of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico.
authors.forename: Brenda
authors.initials: B
authors.lastname: Pereda
authors.affiliation: University of New Mexico School of Medicine Department of Obstetrics and Gynecology, Albuquerque, New Mexico.
authors.forename: Tony
authors.initials: T
authors.lastname: Ogburn
authors.affiliation: University of New Mexico School of Medicine Department of Family and Community Medicine, Albuquerque, New Mexico.
authors.forename: Lawrence
authors.initials: L
authors.lastname: Leeman
mesh_terms: D000028:Abortion, Induced / Q000009:adverse effects*; D000284:Administration, Oral; D000328:Adult; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000009:adverse effects*; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D004311:Double-Blind Method; D005240:Feasibility Studies; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007052:Ibuprofen / Q000008:administration & dosage / Q000009:adverse effects; D009516:New Mexico; D009609:Nitrous Oxide / Q000009:adverse effects*; D010044:Outpatient Clinics, Hospital; D010102:Oxygen Inhalation Therapy; D059408:Pain Management; D017060:Patient Satisfaction; D010865:Pilot Projects; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D055815:Young Adult
chemical_list: D018712:Analgesics, Non-Narcotic; D018685:Anesthetics, Inhalation; D009609:Nitrous Oxide; D007052:Ibuprofen
keywords: First trimester; Nitrous oxide; Pain; Surgical abortion