title: Transjugular liver biopsy.
abstract: Liver biopsy is still the gold standard for evaluation of acute and chronic liver diseases, despite achievements regarding noninvasive diagnosis and staging in liver diseases. Transjugular liver biopsy (TJLB) has proved a good option when ascites and/or significant coagulopathy precludes a percutaneous approach. Because diagnostic hemodynamic procedures can be performed during the same session, it is useful in many clinical settings, regardless of the absence of percuteaneous contraindications. TJLB is a safe technique able to provide good-quality specimens with a low rate of complications. This article presents an overview of TJLB that discusses the technique, applicability, indications, contraindications, complications, and diagnostic accuracy.
authors.affiliation: Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona), C/ Villarroel 173, Barcelona 08036, Spain.
authors.forename: Michel
authors.initials: M
authors.lastname: Ble
authors.affiliation: Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona), C/ Villarroel 173, Barcelona 08036, Spain; Gastroenterology Department, 3rd Medical Clinic, University of Medicine and Pharmacy "Iuliu Hatieganu", Str. Victor Babes 8, Cluj-Napoca 400012, Romania; Gastroenterology Department, Regional Institute of Gastroenterology and Hepatology "O. Fodor", Strada Constanţa 5, Cluj-Napoca 400158, Romania.
authors.forename: Bogdan
authors.initials: B
authors.lastname: Procopet
authors.affiliation: Pathology Department, Hospital Clinic, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), C/ Villarroel 173, Barcelona 08036, Spain; University in Barcelona, Gran Via de les Corts Catalanes, 585, Barcelona 08007, Spain.
authors.forename: Rosa
authors.initials: R
authors.lastname: Miquel
authors.affiliation: Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona), C/ Villarroel 173, Barcelona 08036, Spain; University in Barcelona, Gran Via de les Corts Catalanes, 585, Barcelona 08007, Spain; CIBERehd (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas), Instituto de Salud Carlos III, C/ Monforte de Lemos 3-5, Pabellón 11, Planta 0, Madrid 28029, Spain.
authors.forename: Virginia
authors.initials: V
authors.lastname: Hernandez-Gea
authors.affiliation: Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona), C/ Villarroel 173, Barcelona 08036, Spain; University in Barcelona, Gran Via de les Corts Catalanes, 585, Barcelona 08007, Spain; CIBERehd (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas), Instituto de Salud Carlos III, C/ Monforte de Lemos 3-5, Pabellón 11, Planta 0, Madrid 28029, Spain. Electronic address: jcgarcia@clinic.ub.es.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: García-Pagán
mesh_terms: D001706:Biopsy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis* / Q000473:pathology
keywords: Cirrhosis stage; HVPG; Liver specimen; Menghini needle; Tissue sample quality; Transjugular liver biopsy; Tru-Cut needle; Ultrasound guidance