title: A multicenter study on etiology of acute pancreatitis in Beijing during 5 years.
abstract: OBJECTIVE
  The aim of this study was to determine the etiology tendency of acute pancreatitis (AP) in the Beijing region and the relationship with influencing factors.
  
  
  METHODS
  This retrospective multicenter study enrolled 8 representative general hospitals from January 1, 2006 to December 31, 2010. The etiology tendency was analyzed, and the relationship was defined with sex, aging, severity, mortality, recrudesce rate, length of stay, and hospitalization cost.
  
  
  RESULTS
  The study enrolled 2461 patients. The total number was increasing year by year. Causes included biliary (1372, 55.75%), alcoholism (246, 10%), hypertriglyceridemia (255, 10.36%), and the others (588, 23.89%). Biliary AP was the most frequent primary cause. Hypertriglyceridemic AP increased at a faster rate than alcoholic AP. There was higher proportion of alcoholic and hypertriglyceridemic AP in men than in women. There is an increase of AP patients with ages 40 to 49 years and older than 70 years. Alcoholic and hypertriglyceridemic AP were higher in patients younger than the age of 50 years, and biliary pancreatitis was higher in patients older than 70 years. Severe AP was classified among 736 patients (29.9%). Etiology distribution was different between severe AP and mild AP (P < 0.001). Mortality in the hospital was 1.54%, and there was no difference in each group. Recrudesce of hypertriglyceridemic AP was higher (P < 0.01).
  
  
  CONCLUSIONS
  Acute pancreatitis patients increased year by year in Beijing. Gallstones were the predominant etiological factor. There were different etiology proportion of AP according age, sex, and severity.
authors.affiliation: From the *Department of General Surgery, Xuanwu Hospital, Capital Medical University; †School of Biomedical Engineering, Capital Medical University; ‡Department of General Surgery, Peking Union Medical College Hospital; §Department of General Surgery, Peking University People's Hospital; ║Department of General Surgery, Beijing Friendship Hospital, Capital Medical University; ¶Department of General Surgery, Peking University First Hospital; #Department of General Surgery, Beijing Chaoyang Hospital; **Department of General Surgery, Beijing Haidian Hospital; and ††Department of General Surgery, People's Hospital of Beijing Daxing District, Beijing, China.
authors.forename: Yamin
authors.initials: Y
authors.lastname: Zheng
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhou
authors.forename: Haichao
authors.initials: H
authors.lastname: Li
authors.forename: Jia
authors.initials: J
authors.lastname: Li
authors.forename: Ang
authors.initials: A
authors.lastname: Li
authors.forename: Binrong
authors.initials: B
authors.lastname: Ma
authors.forename: Taiping
authors.initials: T
authors.lastname: Zhang
authors.forename: Quan
authors.initials: Q
authors.lastname: Liao
authors.forename: Yingjiang
authors.initials: Y
authors.lastname: Ye
authors.forename: Zhongtao
authors.initials: Z
authors.lastname: Zhang
authors.forename: Yinmo
authors.initials: Y
authors.lastname: Yang
authors.forename: Zhenjun
authors.initials: Z
authors.lastname: Wang
authors.forename: Zaixing
authors.initials: Z
authors.lastname: Zhang
authors.forename: Jinshan
authors.initials: J
authors.lastname: Yang
authors.forename: Fei
authors.initials: F
authors.lastname: Li
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D042882:Gallstones / Q000175:diagnosis / Q000191:economics / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D017721:Hospital Costs; D006801:Humans; D015228:Hypertriglyceridemia / Q000175:diagnosis / Q000191:economics / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D015994:Incidence; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis / Q000191:economics / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D019512:Pancreatitis, Alcoholic / Q000175:diagnosis / Q000453:epidemiology; D010343:Patient Admission; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors; D013997:Time Factors; D055815:Young Adult