title: MRI negative meningeal myeloma with abducens nerve palsies responding to intrathecal chemotherapy.
abstract: Meningeal involvement of multiple myeloma is rare. A patient with multiple myeloma presented with bilateral abducens nerve palsies. In the MRI neither lytic skull lesions nor meningeal enhancement could be found. The diagnosis was based on CSF studies and cytology. A neurologic remission was achieved with intrathecal chemotherapy.
authors.affiliation: Department of Neurology, Medical University of Vienna, Austria. Electronic address: anna.grisold@meduniwien.ac.at.
authors.forename: A
authors.initials: A
authors.lastname: Grisold
authors.affiliation: Department of Neurology, Medical University of Vienna, Austria.
authors.forename: C
authors.initials: C
authors.lastname: Weber
authors.affiliation: Institute of Neurology, Medical University of Vienna, Austria.
authors.forename: J
authors.initials: J
authors.lastname: Hainfellner
authors.affiliation: Department of Internal Medicine, Medical University of Vienna, Austria.
authors.forename: H
authors.initials: H
authors.lastname: Gisslinger
authors.affiliation: Department of Radiology, Medical University of Vienna, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Kasprian
authors.affiliation: Department of Neurology, Medical University of Vienna, Austria.
authors.forename: E
authors.initials: E
authors.lastname: Auff
authors.affiliation: Department of Neurology, Medical University of Vienna, Austria.
authors.forename: T
authors.initials: T
authors.lastname: Sycha
authors.affiliation: Department of Neurology, Kaiser Franz Josef Hospital of Vienna, Austria.
authors.forename: W
authors.initials: W
authors.lastname: Grisold
mesh_terms: D020434:Abducens Nerve Diseases / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology*; D000368:Aged; D004358:Drug Therapy / Q000379:methods*; D006801:Humans; D007278:Injections, Spinal / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D009101:Multiple Myeloma / Q000150:complications* / Q000473:pathology; D016896:Treatment Outcome
keywords: Complete CNS remission; Intrathecal chemotherapy; Leptomeningeal involvement; Multiple myeloma; Negative MRI