title: Characterization of novel metallacarborane-based sorbents by linear solvation energy relationships.
abstract: Two novel metallacarborane-based stationary phases for high performance liquid chromatography were synthesized and characterized utilizing linear solvation energy relationships concept. Interactions taking place between selected probes (45 analytes) and the stationary phases and the mobile phases consisting of a mixture of acetonitrile with buffer were described by the linear solvation energy relationship model in a broad range of acetonitrile/buffer ratios. The interaction properties of the metallacarborane phases were compared with plain silica, the starting material for the preparation of the metallacarborane phases, and with a typical silica-based reversed-phase sorbent. It was clearly demonstrated that the metallacarborane sorbents provide qualitatively and quantitatively different interactions with respect to both the plain silica and reversed-phase stationary phase. It was shown that these novel phases might have also a separation potential in the area of hydrophilic interaction liquid chromatography.
authors.affiliation: Institute of Chemical Technology, Department of Analytical Chemistry, Technická 5, 166 28, Prague 6, Czech Republic. Electronic address: David.Sykora@vscht.cz.
authors.forename: David
authors.initials: D
authors.lastname: Sýkora
authors.affiliation: Institute of Chemical Technology, Department of Analytical Chemistry, Technická 5, 166 28, Prague 6, Czech Republic.
authors.forename: Kristýna
authors.initials: K
authors.lastname: Rídká
authors.affiliation: Charles University in Prague, Faculty of Science, Department of Physical and Macromolecular Chemistry, Albertov 2030, 128 43, Prague 2, Czech Republic.
authors.forename: Eva
authors.initials: E
authors.lastname: Tesařová
authors.affiliation: Charles University in Prague, Faculty of Science, Department of Physical and Macromolecular Chemistry, Albertov 2030, 128 43, Prague 2, Czech Republic.
authors.forename: Květa
authors.initials: K
authors.lastname: Kalíková
authors.affiliation: Institute of Chemical Technology, Department of Analytical Chemistry, Technická 5, 166 28, Prague 6, Czech Republic.
authors.forename: Robert
authors.initials: R
authors.lastname: Kaplánek
authors.affiliation: Institute of Chemical Technology, Department of Analytical Chemistry, Technická 5, 166 28, Prague 6, Czech Republic.
authors.forename: Vladimír
authors.initials: V
authors.lastname: Král
mesh_terms: D002254:Carbonates / Q000032:analysis* / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods*; D056148:Chromatography, Reverse-Phase / Q000295:instrumentation / Q000379:methods*; D057927:Hydrophobic and Hydrophilic Interactions; D012822:Silicon Dioxide / Q000737:chemistry
chemical_list: D002254:Carbonates; D012822:Silicon Dioxide
keywords: Covalently bonded phase; Hydrophilic interaction liquid chromatography; Linear solvation energy relationships; Liquid chromatography; Metallacarborane; Reversed-phase chromatography