title: Word encoding during sleep is suggested by correlations between word-evoked up-states and post-sleep semantic priming.
abstract: To test whether humans can encode words during sleep we played everyday words to men while they were napping and assessed priming from sleep-played words following waking. Words were presented during non-rapid eye movement (NREM) sleep. Priming was assessed using a semantic and a perceptual priming test. These tests measured differences in the processing of words that had been or had not been played during sleep. Synonyms to sleep-played words were the targets in the semantic priming test that tapped the meaning of sleep-played words. All men responded to sleep-played words by producing up-states in their electroencephalogram. Up-states are NREM sleep-specific phases of briefly increased neuronal excitability. The word-evoked up-states might have promoted word processing during sleep. Yet, the mean performance in the priming tests administered following sleep was at chance level, which suggests that participants as a group failed to show priming following sleep. However, performance in the two priming tests was positively correlated to each other and to the magnitude of the word-evoked up-states. Hence, the larger a participant's word-evoked up-states, the larger his perceptual and semantic priming. Those participants who scored high on all variables must have encoded words during sleep. We conclude that some humans are able to encode words during sleep, but more research is needed to pin down the factors that modulate this ability.
authors.affiliation: Department of Psychology, University of Bern Bern, Switzerland ; Center for Cognition, Learning and Memory, University of Bern Bern, Switzerland.
authors.forename: Simon
authors.initials: S
authors.lastname: Ruch
authors.affiliation: Center for Cognition, Learning and Memory, University of Bern Bern, Switzerland ; Department of Psychiatric Neurophysiology, University Hospital of Psychiatry, University of Bern Bern, Switzerland.
authors.forename: Thomas
authors.initials: T
authors.lastname: Koenig
authors.affiliation: Department of Neurology, Inselspital, Bern University Hospital, University of Bern Bern, Switzerland.
authors.forename: Johannes
authors.initials: J
authors.lastname: Mathis
authors.affiliation: Department of Neurology, Inselspital, Bern University Hospital, University of Bern Bern, Switzerland.
authors.forename: Corinne
authors.initials: C
authors.lastname: Roth
authors.affiliation: Department of Psychology, University of Bern Bern, Switzerland ; Center for Cognition, Learning and Memory, University of Bern Bern, Switzerland.
authors.forename: Katharina
authors.initials: K
authors.lastname: Henke
keywords: NREM sleep; implicit; memory; semantic priming; slow-oscillations; unconscious