title: Diagnosis and management of group B streptococcus in pregnancy.
abstract: Group B streptococcus (GBS) can cause significant maternal and neonatal morbidity. Over the past 30 years, reductions in early-onset GBS neonatal sepsis in the United States have been attributable to the guidelines from the Centers for Disease Control and Prevention for antepartum screening and treating this organism during labor. This article highlights the clinical implications, screening, diagnosis, prophylactic interventions, and future therapies for mothers with GBS during the peripartum period.
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, DUMC 3967, Durham, NC 27710, USA.
authors.forename: Homa K
authors.initials: HK
authors.lastname: Ahmadzia
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Duke University Medical Center, DUMC 3967, Durham, NC 27710, USA. Electronic address: phillip.heine@dm.duke.edu.
authors.forename: R Phillips
authors.initials: RP
authors.lastname: Heine
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology / Q000382:microbiology*; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D047928:Premature Birth; D011296:Prenatal Diagnosis; D012307:Risk Factors; D018805:Sepsis / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D022541:Streptococcal Vaccines; D014481:United States / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents; D022541:Streptococcal Vaccines
keywords: Diagnosis; Group B streptococcus; Intrapartum prophylaxis; Neonate; Pregnancy; Screening