title: Progress in the delivery of nanoparticle constructs: towards clinical translation.
abstract: The application of nanoparticle constructs in drug delivery and nanomedicine is anticipated to have a great impact on future public health. Progress in this area is expected to address some of modern medicine's unresolved problems and recent literature contains many articles discussing this topic. We focus here on recent nanomedicine developments mainly in relation to cancer, which have either being approved for the market or clinical trials. We review nanomedicines in clinical use, nano-construct delivery systems (both non-targeted and targeted), imaging agents, as well as theranostics.
authors.affiliation: School of Veterinary Medicine and Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.
authors.forename: Sinéad M
authors.initials: SM
authors.lastname: Ryan
authors.affiliation: School of Veterinary Medicine and Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Electronic address: David.Brayden@ucd.ie.
authors.forename: David J
authors.initials: DJ
authors.lastname: Brayden
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D003287:Contrast Media; D016503:Drug Delivery Systems; D005290:Ferric Compounds / Q000627:therapeutic use; D006801:Humans; D050997:Nanomedicine; D053758:Nanoparticles / Q000627:therapeutic use; D009369:Neoplasms / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents; D003287:Contrast Media; D005290:Ferric Compounds; C000499:ferric oxide