title: Alterations in pituitary gland volume in polycystic ovary syndrome: a structural magnetic resonance imaging study.
abstract: The purpose of this prospectively designed cross-sectional observational study was to evaluate the effect of polycystic ovary syndrome (PCOS) on pituitary gland volume (PGV) under the hypothesis that endocrinologic changes may lead to morphologic changes of the pituitary gland. Twenty-six PCOS patients and 31 control subjects underwent magnetic resonance imaging (MRI) of the pituitary. Informed consent was obtained from all subjects. PGV was significantly larger in PCOS patients than in control subjects. Luteinizing hormone/follicle-stimulating hormone ratio was the only predictor of PGV. The association between pituitary gland enlargement and PCOS should be kept in mind when pituitary hypertrophy is detected on MRI.
authors.affiliation: Department of Radiology, Afyon Kocatepe University, 03040, Afyonkarahisar, Turkey. Electronic address: edunlu@yahoo.com.
authors.forename: Ebru
authors.initials: E
authors.lastname: Unlu
authors.affiliation: Department of Obstetrics and Gynecology, Afyon Kocatepe University, 03040, Afyonkarahisar, Turkey.
authors.forename: Bekir Serdar
authors.initials: BS
authors.lastname: Unlu
authors.affiliation: Department of Anatomy, Afyon Kocatepe University, 03040, Afyonkarahisar, Turkey.
authors.forename: Ozan
authors.initials: O
authors.lastname: Turamanlar
authors.affiliation: Department of Radiology, Afyon Kocatepe University, 03040, Afyonkarahisar, Turkey.
authors.forename: Mehtap Beker
authors.initials: MB
authors.lastname: Acay
authors.affiliation: Department of Radiology, Afyon Kocatepe University, 03040, Afyonkarahisar, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Kacar
authors.affiliation: Department of Obstetrics and Gynecology, Ilgin State Hospital, 42340, Konya, Turkey.
authors.forename: Yunus
authors.initials: Y
authors.lastname: Yıldız
authors.affiliation: Department of Mechanical Education, Afyon Kocatepe University, 03040, Afyonkarahisar, Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Verim
authors.affiliation: Department of Radiology, Afyon Kocatepe University, 03040, Afyonkarahisar, Turkey.
authors.forename: Nazan
authors.initials: N
authors.lastname: Okur
authors.affiliation: Department of Radiology, Afyon Kocatepe University, 03040, Afyonkarahisar, Turkey.
authors.forename: Cinar
authors.initials: C
authors.lastname: Balcik
authors.affiliation: Department of Mechanical Education, Afyon Kocatepe University, 03040, Afyonkarahisar, Turkey.
authors.forename: Suleyman
authors.initials: S
authors.lastname: Tasgetiren
authors.affiliation: Department of Radiology, Afyon Kocatepe University, 03040, Afyonkarahisar, Turkey.
authors.forename: Aylin
authors.initials: A
authors.lastname: Yucel
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D005640:Follicle Stimulating Hormone; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009929:Organ Size; D010902:Pituitary Gland / Q000473:pathology*; D011085:Polycystic Ovary Syndrome / Q000473:pathology*; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D005640:Follicle Stimulating Hormone
keywords: Magnetic resonance imaging; Mean ovarian volume; Pituitary gland volume; Polycystic ovary syndrome