title: Evaluation and management of hepatocellular carcinoma.
abstract: The burden of hepatocellular carcinoma is rising and anticipated to escalate and while the best chance for long term cure remains transplantation, however the shortage of available organs remains a limitation. Liver directed therapy can serve the role of bridge/downstaging to transplant or as palliative care. Despite an improved overall survival among patients with HCC, due to advancements in surgical techniques, liver directed and systemic therapy, the 5 year overall survival remains low at 18% high-lightening the need for novel therapies. Surveillance for HCC is key to detect disease at an early stage to increase the chances for a potentially curative option.
authors.affiliation: Kovler Organ Transplantation Center, NMH, Arkes Family Pavilion, Suite 1900, 676 North Saint Clair, Chicago, IL 60611, USA. Electronic address: lkulik@nmff.org.
authors.forename: Laura M
authors.initials: LM
authors.lastname: Kulik
authors.affiliation: Kovler Organ Transplantation Center, NMH, Arkes Family Pavilion, Suite 1900, 676 North Saint Clair, Chicago, IL 60611, USA.
authors.forename: Attasit
authors.initials: A
authors.lastname: Chokechanachaisakul
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000628:therapy* / Q000821:virology; D017115:Catheter Ablation; D019694:Hepatitis B, Chronic / Q000150:complications; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000628:therapy* / Q000821:virology; D016031:Liver Transplantation; D011159:Population Surveillance
chemical_list: D000970:Antineoplastic Agents
keywords: Diagnosis; Evaluation; Hepatocellular carcinoma; Management; Treatment