title: Lipidomics in the study of lipid metabolism: Current perspectives in the omic sciences.
abstract: The advances in systems biology and in the development of new technological tools in analysis, as well as in the omic sciences, among which, metabolomics, and more specifically, lipidomics, have made it possible to investigate the structural and functional complexity of lipids in biological systems. Liquid chromatography and mass spectrometry are the analytical approaches most used in lipid research. Biomedical research, with the development of specific markers for lipids, together with new software development, have both enabled the early diagnosis of several illnesses, besides the evaluation of drug activity and treatment efficacy.
authors.affiliation: Post-graduation Program in Interactive Processes of Organs and Systems, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, Brazil.
authors.forename: Ana Emília Holanda
authors.initials: AE
authors.lastname: Rolim
authors.affiliation: Post-graduation Program in Interactive Processes of Organs and Systems, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, Brazil.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Henrique-Araújo
authors.affiliation: Post-graduation Program in Interactive Processes of Organs and Systems, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, Brazil.
authors.forename: Eduardo Gomes
authors.initials: EG
authors.lastname: Ferraz
authors.affiliation: Post-graduation Program in Interactive Processes of Organs and Systems, Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, Brazil.
authors.forename: Fátima Karoline
authors.initials: FK
authors.lastname: de Araújo Alves Dultra
authors.affiliation: Institute of Health Sciences-ICS, Federal University of Bahia-UFBA, Department of Biofunção, Laboratory of Biochemistry, Biotechnology and Bioproducts-LBBB, Salvador, Bahia, Brazil. Electronic address: luzimargonzaga@gmail.com.
authors.forename: Luzimar Gonzaga
authors.initials: LG
authors.lastname: Fernandez
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D002853:Chromatography, Liquid / Q000379:methods; D006801:Humans; D052439:Lipid Metabolism Disorders / Q000378:metabolism; D008055:Lipids / Q000032:analysis* / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods; D055432:Metabolomics / Q000379:methods*; D012984:Software; D049490:Systems Biology
chemical_list: D015415:Biomarkers; D008055:Lipids
keywords: Lipids; Metabolomics; Pharmacolipidomics