title: [Use of group A streptococcal rapid diagnostic test in extra-pharyngeal infections].
abstract: The purpose of this study was to assess the performances of the group A streptococcus (GAS) rapid antigen diagnostic tests (RADTs) in extra-pharyngeal infections. Between October 2009 and June 2014, 368 patients (median age: 48 months) were enrolled. The pathologies involved were : 160 perineal infections (44 %), 69 blistering distal dactylitis (19 %), 55 cervical lymphadenitis (15 %), 31 crusty or bleeding rhinitis (8 %), and 53 other diseases (14 %). The sensitivity of GAS-RADT used was 96 % (95 % CI: 92-99 %), the specificity 81 % (95 % CI: 75- 86 %), the negative predictive value 97 % (CI 95 %: 93-99 %), and the positive predictive value 79 % (95 % CI: 73-85 %). Finally, positive and negative likelihood ratio were 5 (95 % CI: 4-7) and 0.05 (95 % CI: 0.02-0.11) respectively. The GAS-RADTs developed for pharyngitis have comparable performances in these settings and therefore can be used.
authors.affiliation: ACTIV (Association clinique et thérapeutique infantile du Val-de-Marne), 27, rue Inkermann, 94100 Saint-Maur-des-Fossés, France.
authors.forename: A
authors.initials: A
authors.lastname: Wollner
authors.affiliation: ACTIV (Association clinique et thérapeutique infantile du Val-de-Marne), 27, rue Inkermann, 94100 Saint-Maur-des-Fossés, France; Centre de recherche clinique (CRC) et Centre hospitalier intercommunal (CHI), 40, avenue de Verdun, 94010 Créteil, France; AFPA (Association française de pédiatrie ambulatoire), 4, rue Parmentier, 54270 Essey-les-Nancy, France. Electronic address: corinne.levy@activ-france.fr.
authors.forename: C
authors.initials: C
authors.lastname: Levy
authors.affiliation: ACTIV (Association clinique et thérapeutique infantile du Val-de-Marne), 27, rue Inkermann, 94100 Saint-Maur-des-Fossés, France.
authors.forename: M
authors.initials: M
authors.lastname: Benani
authors.affiliation: AFPA (Association française de pédiatrie ambulatoire), 4, rue Parmentier, 54270 Essey-les-Nancy, France.
authors.forename: F
authors.initials: F
authors.lastname: Thollot
authors.affiliation: ACTIV (Association clinique et thérapeutique infantile du Val-de-Marne), 27, rue Inkermann, 94100 Saint-Maur-des-Fossés, France.
authors.forename: S
authors.initials: S
authors.lastname: Béchet
authors.affiliation: INSERM, Epidemiological Research Unit on Perinatal Health and Women's and Children's Health (UMR S953), hôpital Cochin, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Cohen
authors.affiliation: Université Paris-Diderot, PRES Sorbonne-Paris-Cité, 46, rue Henri-Huchard, 75018 Paris, France; Service de microbiologie, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Bonacorsi
authors.affiliation: Université Paris-Diderot, PRES Sorbonne-Paris-Cité, 46, rue Henri-Huchard, 75018 Paris, France; Service de microbiologie, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France.
authors.forename: Ph
authors.initials: P
authors.lastname: Bidet
authors.affiliation: ACTIV (Association clinique et thérapeutique infantile du Val-de-Marne), 27, rue Inkermann, 94100 Saint-Maur-des-Fossés, France; Centre de recherche clinique (CRC) et Centre hospitalier intercommunal (CHI), 40, avenue de Verdun, 94010 Créteil, France; AFPA (Association française de pédiatrie ambulatoire), 4, rue Parmentier, 54270 Essey-les-Nancy, France; Unité court séjour, petits nourrissons, service de néonatologie, CHI de Créteil, 40, avenue de Verdun, 94010 Créteil, France.
authors.forename: R
authors.initials: R
authors.lastname: Cohen
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis*; D002675:Child, Preschool; D005602:France / Q000453:epidemiology; D006801:Humans; D007159:Immunologic Tests; D008199:Lymphadenitis / Q000382:microbiology; D011446:Prospective Studies; D012220:Rhinitis / Q000382:microbiology; D012680:Sensitivity and Specificity; D018461:Soft Tissue Infections / Q000382:microbiology; D013290:Streptococcal Infections / Q000175:diagnosis*; D013297:Streptococcus pyogenes / Q000276:immunology*
chemical_list: D000942:Antigens, Bacterial