title: Multidrug resistant Fusarium keratitis.
abstract: METHODS
  We report a case of keratitis in a female contact lens wearer, who developed a deep corneal abscess. The culture of a corneal biopsy scraping was positive for multiresistant Fusarium solani. The patient has a complicated clinical course and failed to respond to local and systemic antifungal treatment, requiring eye enucleation.
  
  
  CONCLUSIONS
  Fusarium keratitis may progress to severe endophthalmitis. Clinical suspicion is paramount in order to start antifungal therapy without delay. Therapy is complex due to the high resistance of this organism to usual antifungal drugs.
authors.affiliation: Servicio de Microbiología, Hospital Universitario San Juan, Alicante, España.
authors.forename: P
authors.initials: P
authors.lastname: Antequera
authors.affiliation: Servicio de Oftalmología, Hospital Universitario San Juan, Alicante, España.
authors.forename: V
authors.initials: V
authors.lastname: Garcia-Conca
authors.affiliation: Servicio de Microbiología, Hospital Universitario San Juan, Alicante, España.
authors.forename: C
authors.initials: C
authors.lastname: Martín-González
authors.affiliation: Servicio de Microbiología, Hospital Universitario San Juan, Alicante, España. Electronic address: ortiz_vic@gva.es.
authors.forename: V
authors.initials: V
authors.lastname: Ortiz-de-la-Tabla
mesh_terms: D000038:Abscess / Q000209:etiology / Q000382:microbiology / Q000601:surgery; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000494:pharmacology* / Q000627:therapeutic use; D060085:Coinfection; D018639:Contact Lens Solutions; D003261:Contact Lenses; D057210:Delayed Diagnosis; D026141:Drug Resistance, Multiple, Fungal; D004756:Enterobacteriaceae Infections / Q000150:complications / Q000382:microbiology; D015353:Eye Enucleation; D015818:Eye Infections, Bacterial / Q000150:complications / Q000382:microbiology; D015821:Eye Infections, Fungal / Q000150:complications / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D005260:Female; D060585:Fusariosis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D005670:Fusarium / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D007634:Keratitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D008875:Middle Aged; D020636:Pantoea / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D018639:Contact Lens Solutions
keywords: Contact lens; Endoftalmitis; Endophthalmitis; Fusarium solani; Keratitis; Lentes de contacto; Queratitis