title: Potential benefits of potassium deposition with periodic fluid redistribution using periodic head down tilt during diminished muscular activity.
abstract: OBJECTIVE
  Fluid redistribution (FR) is an important cornerstone in treating diseases. Findings of FR with periodic head down tilt (PHDT) had sparked renewed interest in treating electrolyte disturbances. Therefore this study aimed to determine the potential benefits of potassium (K+) deposition with periodic FR by PHDT during diminished muscular activity (hypokinesia; HK).
  
  
  METHODS
  Studies were conducted on 40-male volunteers. They were equally divided into 4-groups: active control subjects (ACS), hypokinetic subjects (HKS), periodic fluid redistribution control subjects (PFRCS) and periodic fluid redistribution hypokinetic subjects (PFRHS).
  
  
  RESULTS
  Muscle K+ increased (p < 0.05) and plasma K+ level and K+ losses decreased (p < 0.05) in the PFRHS group compared to the HKS group. By contrast in the HKS group muscle K+ reduced (p < 0.05) and plasma K+ level and K+ losses increased (p < 0.05) compared to pre-experimental period levels and the values of the other groups. In the PFRCS group the muscle K+, plasma K+ concentration and K+ losses were affected much less than in the PFRHS group.
  
  
  CONCLUSIONS
  The current study shows that periodic-applied fluid volume addition into the body's regional areas by PHDT increases muscle K+ content and decrease K+ losses suggesting potential benefits of K+ deposition during diminished muscular activity.
authors.forename: Yuri F
authors.initials: YF
authors.lastname: Federenko
authors.forename: Pavel L
authors.initials: PL
authors.lastname: Merkov
authors.forename: Yuri N
authors.initials: YN
authors.lastname: Yaroshenko
authors.forename: Sergei K
authors.initials: SK
authors.lastname: Denogratov
authors.forename: Kyrill P
authors.initials: KP
authors.lastname: Charapakhin
authors.forename: Nikolai H
authors.initials: NH
authors.lastname: Neofitov
mesh_terms: D000255:Adenosine Triphosphate / Q000096:biosynthesis; D000328:Adult; D018475:Head-Down Tilt; D006801:Humans; D018476:Hypokinesia / Q000378:metabolism*; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism; D010085:Oxidative Phosphorylation; D011188:Potassium / Q000378:metabolism*; D055815:Young Adult
chemical_list: D000255:Adenosine Triphosphate; D011188:Potassium