title: Pulmonary endarterectomy for saddling pulmonary embolism by Aspergillus fungus in an immunocompetent patient.
abstract: We present a case of tricuspid valve Aspergillus endocarditis with saddle shaped massive pulmonary embolism occurring in an immunocompetent host. The patient was managed uniquely by pulmonary endarterectomy (PEA) and combination antifungal chemotherapy with Liposomal amphotericin-B + caspofungin.
authors.affiliation: Professor, Department of Cardio-thoracic Surgery, G B Pant Hospital, New Delhi 110002, India.
authors.forename: Harpreet Singh
authors.initials: HS
authors.lastname: Minhas
authors.affiliation: Ex-Assistant Professor, Department of Cardiology, G B Pant Hospital, New Delhi 110002, India. Electronic address: jain_dr_sms@yahoo.co.in.
authors.forename: Gagan
authors.initials: G
authors.lastname: Jain
authors.affiliation: Senior Resident, Department of Cardio-thoracic Surgery, G B Pant Hospital, New Delhi 110002, India.
authors.forename: Chirantan
authors.initials: C
authors.lastname: Mangukia
authors.affiliation: Senior Resident, Department of Cardiology, G B Pant Hospital, New Delhi 110002, India.
authors.forename: Mayank
authors.initials: M
authors.lastname: Goyal
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000628:therapy*; D000077336:Caspofungin; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D054714:Echinocandins / Q000627:therapeutic use; D004691:Endarterectomy; D004696:Endocarditis / Q000382:microbiology / Q000628:therapy*; D005260:Female; D006349:Heart Valve Diseases / Q000382:microbiology / Q000628:therapy*; D006801:Humans; D055666:Lipopeptides / Q000627:therapeutic use; D011655:Pulmonary Embolism / Q000382:microbiology* / Q000628:therapy*; D014261:Tricuspid Valve; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; C068538:liposomal amphotericin B; D000666:Amphotericin B; D000077336:Caspofungin
keywords: Fungal endocarditis; Pulmonary embolism; Pulmonary endarterectomy