title: Correlation between cardiac autonomic modulation in response to orthostatic stress and indicators of quality of life, physical capacity, and physical activity in healthy individuals.
abstract: Increased heart rate variability (HRV) at rest is frequently associated to maximal oxygen uptake (VO2max), physical activity, and markers of quality of life (QoL). However, the HRV has not been observed during physical exercise or orthostatic (ORT) challenge. This study investigated the associations of HRV changes (ΔHRV) from rest at supine (SUP) to ORT positions with (VO2max), physical activity level, and QoL in young adults. Cardiac autonomic modulation was assessed by spectral analysis of R-R time series measured from SUP to ORT positions in 15 healthy volunteers (26 ± 7 years). Questionnaires were applied for evaluation of QoL (SF-36 score), to estimate (VO2max), and to quantify physical activity (Baecke Sport Score). All HRV indices at SUP, but not ORT, strongly correlated to QoL, estimated (VO2max), and physical activity. The ΔHRV from SUP to ORT showed significant correlations with all questionnaire scores (r = 0.52-0.61 for low frequency and r = -0.61 to -0.65 for high frequency, p ≤ 0.05). Higher vagal activity at rest and greater changes in adrenergic and parasympathetic modulation from SUP to ORT were detected in the volunteers exhibiting higher scores of QoL, estimated (VO2max), and physical activity. Taken together, the level of neural adaptations from resting SUP position to active standing, and physical activity and QoL questionnaires seem to be a simple approach to understand the physiological and lifestyle adaptations to exercise that may be applied to a large sample of subjects in almost any sports facilities at a low cost.
authors.affiliation: 1Laboratory of Experimental and Applied Exercise Physiology, Department of Physiology and Pharmacology, Biomedical Institute, Fluminense Federal University, Niterói, Brazil; 2Physical Activity and Health Promotion Laboratory, Physical Education Institute, Rio de Janeiro State University, Rio de Janeiro, Brazil; and 3Research Group on Biomechanics, Physical Education Institute, Fluminense Federal University, Niterói, Brazil.
authors.forename: Thiago R
authors.initials: TR
authors.lastname: Gonçalves
authors.forename: Paulo de Tarso Veras
authors.initials: Pde T
authors.lastname: Farinatti
authors.forename: Jonas L
authors.initials: JL
authors.lastname: Gurgel
authors.forename: Pedro P
authors.initials: PP
authors.lastname: da Silva Soares
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology; D000328:Adult; D001341:Autonomic Nervous System / Q000502:physiology*; D015444:Exercise / Q000502:physiology; D017079:Exercise Tolerance / Q000502:physiology; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008019:Life Style; D008297:Male; D010101:Oxygen Consumption; D011788:Quality of Life; D012146:Rest / Q000502:physiology; D016683:Supine Position / Q000502:physiology*; D011795:Surveys and Questionnaires; D055815:Young Adult