title: Spatial organization of bacterial chromosomes.
abstract: Bacterial chromosomes are organized in stereotypical patterns that are faithfully and robustly regenerated in daughter cells. Two distinct spatial patterns were described almost a decade ago in our most tractable model organisms. In recent years, analysis of chromosome organization in a larger and more diverse set of bacteria and a deeper characterization of chromosome dynamics in the original model systems have provided a broader and more complete picture of both chromosome organization and the activities that generate the observed spatial patterns. Here, we summarize these different patterns highlighting similarities and differences and discuss the protein factors that help establish and maintain them.
authors.affiliation: Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
authors.forename: Xindan
authors.initials: X
authors.lastname: Wang
authors.forename: David Z
authors.initials: DZ
authors.lastname: Rudner
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism; D001419:Bacteria / Q000235:genetics* / Q000378:metabolism; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism; D018797:Cell Cycle Proteins / Q000737:chemistry / Q000378:metabolism; D002876:Chromosomes, Bacterial / Q000235:genetics* / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism; D040342:Genetic Structures; D046912:Multiprotein Complexes / Q000378:metabolism; D018741:Replication Origin; D016615:Telomere
chemical_list: D001426:Bacterial Proteins; D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; C104636:DivIVA protein, bacteria; D046912:Multiprotein Complexes; C052883:chromosome partition proteins, bacterial; C108312:condensin complexes; D000251:Adenosine Triphosphatases