title: Metastatic malignant phyllodes tumor involving the cerebellum.
abstract: Brain metastases from malignant phyllodes tumors of the breast are a rare occurrence. We report a patient with a malignant phyllodes tumor of the right breast which subsequently metastasized to the right lower lobe of the lung 1 year after initial presentation, and to the right cerebellar hemisphere 2 years after diagnosis of her breast mass. After both chemotherapy and whole brain radiotherapy the patient is tumor free at most recent follow-up, 116 months after the breast tumor diagnosis was made. The literature is briefly reviewed and the differential diagnosis of malignant spindle cell brain tumors is discussed.
authors.affiliation: Department of Pathology, L25, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
authors.forename: J Jordi
authors.initials: JJ
authors.lastname: Rowe
authors.affiliation: Department of Pathology, L25, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address: praysor@ccf.org.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Prayson
mesh_terms: D000328:Adult; D001706:Biopsy; D001943:Breast Neoplasms / Q000601:surgery*; D002528:Cerebellar Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D059248:Chemoradiotherapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D003557:Phyllodes Tumor / Q000473:pathology / Q000556:secondary* / Q000601:surgery
keywords: Brain tumor; Cystosarcoma phyllodes; Metastasis