title: Historic overview of allergy research in the Netherlands.
abstract: Research in allergy has a long history in the Netherlands, although the relation with immunology has not always been appreciated. In many aspects Dutch researchers have made major contribution in allergy research. This ranges from the first characterization of house dust mite as an important allergen, the first characterization of human Th2 and Th1 T cell clones, to the development of diagnostic test systems. In this overview Aalberse and Knol have made an overview of the major contributions of Dutch immunologists in allergy.
authors.affiliation: Department of Immunopathology, Sanquin Blood Supply Foundation and Academic Medical Centre, Amsterdam, The Netherlands.
authors.forename: Rob C
authors.initials: RC
authors.lastname: Aalberse
authors.affiliation: Department of Immunology, University Medical Center Utrecht, The Netherlands; Department of Dermatology and Allergology, University Medical Center Utrecht, The Netherlands. Electronic address: e.f.knol@umcutrecht.nl.
authors.forename: Edward F
authors.initials: EF
authors.lastname: Knol
mesh_terms: D000485:Allergens / Q000276:immunology*; D000818:Animals; D035843:Biomedical Research / Q000266:history*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000266:history / Q000276:immunology; D018417:Th1 Cells / Q000276:immunology*; D018418:Th2 Cells / Q000276:immunology*
chemical_list: D000485:Allergens
keywords: Allergens; Allergy; Basophils; Eosinophils; IgE; Th2 lymphocytes