title: Delayed intravenous contrast-enhanced 3D FLAIR MRI in Meniere's disease: correlation of quantitative measures of endolymphatic hydrops with hearing.
abstract: OBJECTIVE
  Using three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI), our goal was to correlate quantifiable measures of endolymphatic hydrops (EH) with auditory function in the setting of Meniere's disease (MD).
  
  
  METHODS
  Forty-one ears were analyzed in 21 subjects (12 ears with MD, 29 without MD). Vestibular endolymphatic space size measurements obtained with two different techniques were referenced against clinical data.
  
  
  RESULTS
  EH was better evaluated on 3D maximum intensity projections (MIPs) than on two-dimensional (2D) images. Using MIPs, quantitative assessments EH correlated with severity of hearing impairment.
  
  
  CONCLUSIONS
  3D MIPs were superior to 2D images for evaluating EH in the setting of MD.
authors.affiliation: Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA USA. Electronic address: ali.sepahdari@gmail.com.
authors.forename: Ali R
authors.initials: AR
authors.lastname: Sepahdari
authors.affiliation: Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA USA.
authors.forename: Gail
authors.initials: G
authors.lastname: Ishiyama
authors.affiliation: Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA USA.
authors.forename: Nopawan
authors.initials: N
authors.lastname: Vorasubin
authors.affiliation: Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA USA.
authors.forename: Kevin A
authors.initials: KA
authors.lastname: Peng
authors.affiliation: Department of Radiological Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Linetsky
authors.affiliation: Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA USA.
authors.forename: Akira
authors.initials: A
authors.lastname: Ishiyama
mesh_terms: D000328:Adult; D000368:Aged; D007758:Ear, Inner / Q000473:pathology* / Q000503:physiopathology; D018159:Endolymphatic Hydrops / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006309:Hearing / Q000502:physiology*; D006320:Hearing Tests; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008575:Meniere Disease / Q000473:pathology* / Q000503:physiopathology; D008875:Middle Aged
keywords: 3D FLAIR; Endolymphatic hydrops; Inner ear; Meniere's disease