title: New polyoxypregnane glycosides from the roots of Marsdenia tenacissima.
abstract: For the first time, a systematic phytochemical study was performed on the roots of Marsdenia tenacissima. Finally, sixteen new polyoxypregnane glycosides, marstenacissides A1-A7 (1-7) and marstenacissides B1-B9 (8-16), were isolated from M. tenacissima roots. The structures of these new compounds were established by various spectroscopic techniques, including 1D and 2D NMR spectroscopy and mass spectrometry.
authors.affiliation: Beijing Institute of Radiation Medicine, Beijing 100850, China; Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Pang
authors.affiliation: State Key Laboratory of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China; Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. Electronic address: kang_liping21@163.com.
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Kang
authors.affiliation: Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
authors.forename: He-Shui
authors.initials: HS
authors.lastname: Yu
authors.affiliation: Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China.
authors.forename: Li-Feng
authors.initials: LF
authors.lastname: Han
authors.affiliation: Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Cheng-Qi
authors.initials: CQ
authors.lastname: Xiong
authors.affiliation: Yunnan Branch of Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Jinghong 666100, China.
authors.forename: Li-Xia
authors.initials: LX
authors.lastname: Zhang
authors.affiliation: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.
authors.forename: Li-Yan
authors.initials: LY
authors.lastname: Yu
authors.affiliation: Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address: mabaiping@sina.com.
authors.forename: Bai-Ping
authors.initials: BP
authors.lastname: Ma
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D031101:Marsdenia / Q000737:chemistry*; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry*; D011278:Pregnanes / Q000737:chemistry* / Q000302:isolation & purification; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: C575295:12-0-benzoyl-8,11-ditigloyl-3,8,11,12-pentahydroxy-pregn-14-ol, 20-one 3-0-methyl-allopyranosyl(1-4)-thevetopyranoside; D010936:Plant Extracts; D011278:Pregnanes; D012503:Saponins
keywords: Asclepiadaceae; Marsdenia tenacissima; Marstenacissides; Polyoxypregnane glycosides