title: Neuro-ophthalmic manifestations of prematurity.
abstract: Increasing rates of preterm births coupled with better survival of these infants have resulted in higher prevalence of systemic and ocular complications associated with prematurity. In addition to retinopathy of prematurity, infants who are born preterm may suffer from severe visual impairment as a result of hypoxic ischemic encephalopathy, hypoglycemia, and other metabolic imbalances. The effect of these processes on the anterior visual pathway may result in optic atrophy, optic nerve hypoplasia or optic disc cupping and affection of the posterior visual pathway leads to cortical visual impairment (CVI). Other ocular associations include strabismus, nystagmus, and ocular motor abnormalities such as tonic down gaze and defective saccades and pursuits. Cortical and subcortical involvement also manifests as defects in functional vision and these have not yet been completely understood. Children with CVI may have visual field defects, photophobia, defective visual processing, and deficient color vision. Since most of these children also suffer from additional systemic disabilities, evaluation, and management remains a challenge. However, early diagnosis and initiation of rehabilitation therapy can prove to be of significant benefit in these children.
authors.affiliation: Department of Pediatric Ophthalmology and Neuro-ophthalmology, Jasti V Ramanamma Children's Eye Care Center, L. V. Prasad Eye Institute, KAR Campus, Banjara Hills, Hyderabad, India.
authors.forename: Preeti Patil
authors.initials: PP
authors.lastname: Chhablani
authors.forename: Ramesh
authors.initials: R
authors.lastname: Kekunnaya
mesh_terms: D019468:Disease Management; D014943:Global Health; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D014786:Vision Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D014792:Visual Acuity / Q000502:physiology*