title: Initial experience with real-time elastography using an ultrasound bronchoscope for the evaluation of mediastinal lymph nodes.
abstract: Real-time elastography performed during endoscopic ultrasonography is a relatively new method for characterizing tissue stiffness, and has been used successfully as a predictor of malignancy in mediastinal lymph nodes. This case report describes our practical experience with this technique using an ultrasound bronchoscope to examine mediastinal lymph nodes. We present a case of sectorial endobronchial ultrasound and the first published case of endoscopic ultrasound elastography using ultrasound bronchoscope in two patients with non-small cell lung carcinoma. Qualitative tissue color pattern was obtained in both cases and correlated with pathological evaluation. The initial feasibility results are promising and suggest that ultrasound bronchoscopy techniques, such as guided nodal staging, merit additional studies. It may be important to categorize the risk of malignancy to facilitate sampling decisions.
authors.affiliation: Servicio de Neumología, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, España; Departamento de Medicina, Universidad Autónoma de Barcelona, Barcelona, España. Electronic address: fandreo@separ.es.
authors.forename: Felipe
authors.initials: F
authors.lastname: Andreo García
authors.affiliation: Servicio de Neumología, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, España.
authors.forename: Carmen Ángela
authors.initials: CÁ
authors.lastname: Centeno Clemente
authors.affiliation: Servicio de Neumología, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, España.
authors.forename: José
authors.initials: J
authors.lastname: Sanz Santos
authors.affiliation: Servicio de Aparato Digestivo, Hospital Universitario de Cruces, Baracaldo, Vizcaya, España.
authors.forename: Ángel
authors.initials: Á
authors.lastname: Barturen Barroso
authors.affiliation: Servicio de Anatomía Patológica, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, España.
authors.forename: Alba
authors.initials: A
authors.lastname: Hernández Gallego
authors.affiliation: Servicio de Neumología, Hospital Universitario Germans Trias i Pujol, Badalona, Barcelona, España; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, España; Departamento de Medicina, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: Juan
authors.initials: J
authors.lastname: Ruiz Manzano
mesh_terms: D000368:Aged; D001999:Bronchoscopy / Q000379:methods*; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging / Q000556:secondary*; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000556:secondary*; D015897:Comorbidity; D003199:Computer Systems; D054459:Elasticity Imaging Techniques / Q000295:instrumentation / Q000379:methods*; D019160:Endosonography / Q000379:methods*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging*; D008297:Male; D008482:Mediastinum / Q000000981:diagnostic imaging; D009367:Neoplasm Staging / Q000379:methods*
keywords: Cáncer de pulmón; Elastografía; Elastography; Endobronchial ultrasound; Endoscopic ultrasound; Lung cancer; Ultrasonografía endobronquial; Ultrasonografía endoscópica