title: Two target locations for corneal inlay implantation combined with laser in situ keratomileusis.
abstract: OBJECTIVE
  To compare the visual acuity outcomes between 2 target locations for corneal inlay implantation with concurrent laser in situ keratomileusis (LASIK) to compensate for presbyopia.
  
  
  METHODS
  Shinagawa LASIK Center, Tokyo, Japan.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  Bilateral LASIK was performed simultaneously with inlay implantation in the nondominant eye. The preoperative and 6-month postoperative uncorrected distance (UDVA) and uncorrected near (UNVA) visual acuities were evaluated. Patients were divided into the following 2 groups based on the pupil center to Purkinje reflex distance (Pp-Pk): small (≤300 μm) and large (>300 μm). Each group was divided into subgroups according to the distance of the inlay center to the Purkinje reflex (I-Pk) or to the midpoint between the pupil center and Purkinje reflex (I-M). The inlay position was classified as 0 to 100 μm, 101 to 200 μm, 201 to 300 μm, and 301 to 400 μm from the Purkinje reflex and from the midpoint.
  
  
  RESULTS
  Of 1008 patients, 992 were available for postoperative follow-up. The UDVA and UNVA improved in both subgroups with all inlay positions (P < .0001). There were no statistically significant differences in UDVA or UNVA within or between the small Pp-Pk group and the large Pp-Pk group (P > .05). The Spearman rank-order correlation showed weak associations between the inlay distance and visual acuity.
  
  
  CONCLUSIONS
  The amount of inlay decentration had no influence on postoperative visual acuity.
  
  
  BACKGROUND
  Dr. Tomita is a consultant to Acufocus, Inc. No other author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From Shinagawa LASIK Center (Corpuz, Kanamori, Huseynova, Tomita), Tokyo, Japan; the Department of Ophthalmology (Tomita), Wenzhou Medical College, Wenzhou, China.
authors.forename: Christine Carole C
authors.initials: CC
authors.lastname: Corpuz
authors.affiliation: From Shinagawa LASIK Center (Corpuz, Kanamori, Huseynova, Tomita), Tokyo, Japan; the Department of Ophthalmology (Tomita), Wenzhou Medical College, Wenzhou, China.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Kanamori
authors.affiliation: From Shinagawa LASIK Center (Corpuz, Kanamori, Huseynova, Tomita), Tokyo, Japan; the Department of Ophthalmology (Tomita), Wenzhou Medical College, Wenzhou, China.
authors.forename: Tukezban
authors.initials: T
authors.lastname: Huseynova
authors.affiliation: From Shinagawa LASIK Center (Corpuz, Kanamori, Huseynova, Tomita), Tokyo, Japan; the Department of Ophthalmology (Tomita), Wenzhou Medical College, Wenzhou, China. Electronic address: tomita@eyecanmedical.com.
authors.forename: Minoru
authors.initials: M
authors.lastname: Tomita
mesh_terms: D000328:Adult; D000368:Aged; D001672:Biocompatible Materials; D003319:Corneal Stroma / Q000601:surgery*; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011145:Polyvinyls; D011305:Presbyopia / Q000503:physiopathology / Q000601:surgery*; D019736:Prostheses and Implants; D019919:Prosthesis Implantation; D012030:Refractive Errors / Q000503:physiopathology / Q000628:therapy*; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology*; D005465:Fluorocarbon Polymers
chemical_list: D001672:Biocompatible Materials; D011145:Polyvinyls; C024865:polyvinylidene fluoride; D005465:Fluorocarbon Polymers