title: Repair of tegmen defect using cranial particulate bone graft.
abstract: Bone paté is used to repair cranial bone defects. This material contains bone-dust collected during the high-speed burring of the cranium. Clinical and experimental studies of bone dust, however, have shown that it does not have biological activity and is resorbed. We describe the use of bone paté using particulate bone graft. Particulate graft is harvested with a hand-driven brace and 16mm bit; it is not subjected to thermal injury and its large size resists resorption. Bone paté containing particulate graft is much more likely than bone dust to contain viable osteoblasts capable of producing new bone.
authors.affiliation: Department of Plastic and Oral Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA. Electronic address: arin.greene@childrens.harvard.edu.
authors.forename: Arin K
authors.initials: AK
authors.lastname: Greene
authors.affiliation: Department of Otolaryngology, Boston Children's Hospital, Harvard Medical School, Boston, MA.
authors.forename: Dennis S
authors.initials: DS
authors.lastname: Poe
mesh_terms: D000328:Adult; D016025:Bone Transplantation / Q000379:methods*; D003399:Craniotomy; D004391:Dust; D004432:Ear, Middle / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D052638:Particulate Matter; D019651:Plastic Surgery Procedures / Q000379:methods*; D012886:Skull; D023822:Tissue Engineering; D020858:Tissue and Organ Harvesting; D014057:Tomography, X-Ray Computed / Q000379:methods; D014182:Transplantation, Autologous; D016896:Treatment Outcome
chemical_list: D004391:Dust; D052638:Particulate Matter