title: [Eccrine porocarcinoma with Bowenoid changes: a challenging diagnosis of adnexal neoplasm].
abstract: Eccrine porocarcinoma is a rare malignant sweat gland tumor, representing less than 0.01% of all cutaneous neoplasms, with eccrin differentiation. Its acrosynringeal origin and physiopathology still remain discussed. The prognosis of this carcinoma is held to be poor with a significant risk of lymph node metastasis and local recurrence. Also, this not specific tumor can be a challenging histological diagnosis, in particular, in Bowenoid variant. We report a case of Bowenoid and keratinizing variant of eccrine porocarcinoma of the left ring finger with pejorative evolution and initial diagnosis of infiltrating squamous cell carcinoma arising in Bowen's disease. The knowledge of these patterns and identification of eccrine differentiation of the tumor are essential for the diagnosis and for adapted therapeutic care.
authors.affiliation: Service de pathologie, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France. Electronic address: kottler.diane@gmail.com.
authors.forename: Diane
authors.initials: D
authors.lastname: Kottler
authors.affiliation: Service de pathologie, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Rivet
authors.affiliation: Service de dermatologie, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: Geoffroy
authors.initials: G
authors.lastname: Hickman
authors.affiliation: Service de dermatologie, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: Christelle
authors.initials: C
authors.lastname: Comte
authors.affiliation: Service de chirurgie plastique, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: Jean-Brice
authors.initials: JB
authors.lastname: Duron
authors.affiliation: Service de dermatologie, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: Nicole
authors.initials: N
authors.lastname: Basset-Seguin
authors.affiliation: Service de dermatologie, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: Celeste
authors.initials: C
authors.lastname: Lebbe
authors.affiliation: Service de dermatologie, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: Martine
authors.initials: M
authors.lastname: Bagot
authors.affiliation: Service de pathologie, hôpital Saint-Louis, AP-HP, 1, avenue Claude-Vellefaux, 75010 Paris, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Janin
mesh_terms: D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000032:analysis; D001913:Bowen's Disease / Q000473:pathology*; D057090:Eccrine Porocarcinoma / Q000473:pathology*; D005260:Female; D005385:Fingers; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012878:Skin Neoplasms / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: Bowen's disease; Bowenoid variant; Carcinome épidermoïde; Eccrine porocarcinoma; Immunochemistry; Immunohistochimie; Maladie de Bowen; Porocarcinome eccrine; Squamous cell carcinoma; Variant bowénoïde