title: IgG4-related lung disease with organizing pneumonia effectively treated with azathioprine.
abstract: Immunoglobulin (Ig)-G4-related disease is a multi-organ disease that may affect the lung. We herein describe a patient with IgG4-related lung disease (IgG4-RLD) who was radiologically and pathologically diagnosed with organizing pneumonia. He was successfully treated with a combination of prednisolone (PSL) and azathioprine (AZA), and his clinical course has been uneventful since tapering off PSL. This is a rare case of IgG4-RLD manifesting as organizing pneumonia, and, to our knowledge, this is also the first case showing the effectiveness of AZA in treating IgG4-RLD.
authors.affiliation: Department of Respiratory Medicine, National Hospital Organization Himeji Medical Center, Japan.
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Onishi
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Kawamura
authors.forename: Ryogo
authors.initials: R
authors.lastname: Kagami
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Nakahara
authors.forename: Mochiduki
authors.initials: M
authors.lastname: Yoshiro
mesh_terms: D000368:Aged; D015551:Autoimmunity; D001379:Azathioprine / Q000008:administration & dosage*; D018549:Cryptogenic Organizing Pneumonia / Q000188:drug therapy / Q000276:immunology* / Q000503:physiopathology; D004359:Drug Therapy, Combination; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008171:Lung Diseases / Q000188:drug therapy / Q000276:immunology* / Q000503:physiopathology; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D007074:Immunoglobulin G; D011239:Prednisolone; D001379:Azathioprine