title: [Evaluation of vaginal dysfunction in symptomatic and asymptomatic pregnant women by using the analysis of basic vaginal states (BVS) and its comparison with the conventional microbiological study].
abstract: Infections of the lower genital tract associated to maternal and perinatal complications frequently occur during pregnancy. The aim of this study was to evaluate vaginal dysfunction through the analysis of basic vaginal states (BVS) using the methodology of balance of the vaginal content (BAVACO) and to compare it with the microbiological study of candidiasis, trichomoniasis and bacterial vaginosis (BV). Pregnant patients (1238) were examined from 2010 to 2012. In asymptomatic (A) (n: 1046) and symptomatic pregnant women (S) (n: 192) BVS I was 59.5% and 26% of the patients, respectively. BVS II was observed in 19.7% of A and in 17.2% of S. BVS III was only detected in A in 0.4%. BVS IV was observed in 14.4% of A and in 38% of S. BVS V was detected in 6% of A and in 18.8% of S. Yeasts were associated to BVS I and II in 55.5% and 23.2% of A, respectively; and in 32.4% and 31% of S, respectively. Trichomonas were associated to BVS I in 50% of A, to IV in 44.4% of S and to V in 33.3% of S. BAVACO susceptibility to detect yeasts was 80.4% and 85.5% in A and S, respectively; 40% and 75% in A and S, respectively, to detect trichomonas and 100% in A and S to detect BV. BAVACO specificity was 100% for all pathogens in A and S. The study of BVS proved useful as a guide to evaluate vaginal dysfunction, regardless of symptomatology. Therefore, this study is recommended as prenatal control.
authors.affiliation: Laboratorio de Bacteriología Clínica, Departamento de Bioquímica Clínica, Hospital de Clínicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina. Electronic address: stouzon@hotmail.com.
authors.forename: María S
authors.initials: MS
authors.lastname: Touzon
authors.affiliation: Laboratorio de Bacteriología Clínica, Departamento de Bioquímica Clínica, Hospital de Clínicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
authors.forename: Mirta
authors.initials: M
authors.lastname: Losada
authors.affiliation: Tracto Genital Inferior, Primera Cátedra de Obstetricia, Hospital de Clínicas, Universidad de Buenos Aires, Argentina.
authors.forename: Martha Cora
authors.initials: MC
authors.lastname: Eliseht
authors.affiliation: Laboratorio de Parasitología Clínica, Departamento de Bioquímica Clínica, Hospital de Clínicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
authors.forename: Claudia
authors.initials: C
authors.lastname: Menghi
authors.affiliation: Laboratorio de Parasitología Clínica, Departamento de Bioquímica Clínica, Hospital de Clínicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
authors.forename: Claudia
authors.initials: C
authors.lastname: Gatta
authors.affiliation: Laboratorio de Bacteriología Clínica, Departamento de Bioquímica Clínica, Hospital de Clínicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Santa Cruz
authors.affiliation: Tracto Genital Inferior, Primera Cátedra de Obstetricia, Hospital de Clínicas, Universidad de Buenos Aires, Argentina.
authors.forename: Hilda
authors.initials: H
authors.lastname: Malamud de Ruda Vega
authors.affiliation: Laboratorio de Bacteriología Clínica, Departamento de Bioquímica Clínica, Hospital de Clínicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
authors.forename: Carlos
authors.initials: C
authors.lastname: Vay
authors.affiliation: Tracto Genital Inferior, Primera Cátedra de Obstetricia, Hospital de Clínicas, Universidad de Buenos Aires, Argentina.
authors.forename: Silvio
authors.initials: S
authors.lastname: Tatti
authors.affiliation: Laboratorio de Bacteriología Clínica, Departamento de Bioquímica Clínica, Hospital de Clínicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
authors.forename: Angela
authors.initials: A
authors.lastname: Famiglietti
authors.affiliation: Laboratorio de Bacteriología Clínica, Departamento de Bioquímica Clínica, Hospital de Clínicas, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Perazzi
mesh_terms: D058070:Asymptomatic Diseases; D002181:Candidiasis, Vulvovaginal / Q000453:epidemiology / Q000382:microbiology*; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006801:Humans; D007958:Leukocyte Count; D064307:Microbiota; D011237:Predictive Value of Tests; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000382:microbiology*; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013194:Staining and Labeling / Q000379:methods; D014247:Trichomonas Vaginitis / Q000453:epidemiology / Q000382:microbiology*; D014246:Trichomonas vaginalis / Q000302:isolation & purification; D014621:Vagina / Q000382:microbiology*; D016585:Vaginosis, Bacterial / Q000453:epidemiology / Q000382:microbiology*; D015003:Yeasts / Q000302:isolation & purification
keywords: BVS; Disfunción vaginal; EVB; Embarazo; Estudio microbiológico; Microbiological study; Pregnancy; Vaginal dysfunction