title: Multivariable analysis of anesthetic factors associated with time to extubation in dogs.
abstract: The purpose of this study was to identify factors that prolong the time to extubation in dogs. Anesthetic records of 900 dogs at a university teaching hospital were searched. Multiple linear regression was used to compare independent predictors (patient demographics, anesthetic and intraoperative variables) with the dependent variable (time to extubation). Induction with propofol (P < 0.025) was associated with a shorter time to extubation, while premedication with acepromazine (P = 0.000) was associated with a longer time to extubation. Time to extubation was increased by 0.311 minutes for every kilogram increase in body weight (P = 0.000), 5.924 minutes for every 1 °C loss in body temperature (P = 0.0000), and by 0.096 minutes for every 1 minute increase in anesthetic duration (P = 0.000). Anesthetic variables, which can be manipulated by the anesthetist, include choice of premedication and induction drugs, hypothermia, and duration of anesthesia.
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30605, USA. Electronic address: sakleine@gmail.com.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Kleine
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30605, USA.
authors.forename: Erik
authors.initials: E
authors.lastname: Hofmeister
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA 30605, USA.
authors.forename: Katrina
authors.initials: K
authors.lastname: Egan
mesh_terms: D000075:Acepromazine / Q000008:administration & dosage*; D060666:Airway Extubation / Q000662:veterinary*; D000758:Anesthesia / Q000379:methods / Q000662:veterinary*; D000777:Anesthetics / Q000008:administration & dosage*; D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D001835:Body Weight; D004285:Dogs; D016014:Linear Models; D015999:Multivariate Analysis; D015742:Propofol / Q000008:administration & dosage*; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D000777:Anesthetics; D000075:Acepromazine; D015742:Propofol
keywords: Anesthesia; Dog; Extubation; Recovery