title: Correlation of corneal thickness and volume with intraoperative phacoemulsification parameters using Scheimpflug imaging and optical coherence tomography.
abstract: OBJECTIVE
  To evaluate post-phacoemulsification corneal edema using central corneal thickness (CCT) and central corneal volume (CCV) derived from Scheimpflug imaging, optical coherence tomography (OCT), and ultrasound (US) pachymetry and to correlate CCV with phacoemulsification parameters.
  
  
  METHODS
  Department of Ophthalmology, Boston Medical Center, Boston, Massachusetts, USA.
  
  
  METHODS
  Prospective case study.
  
  
  METHODS
  Scheimpflug imaging (Pentacam HR), OCT (Cirrus HD-OCT), and US pachymetry (Pachmate) were used to measure the CCT, CCV, and phacoemulsification parameters after uneventful phacoemulsification over a 1-month follow-up.
  
  
  RESULTS
  In the 16 eyes assessed, the Scheimpflug CCT was less than the US CCT preoperatively (P=.01) and 1 week postoperatively (P=.02). The OCT CCT was less than the US CCT at 1 week and 1 month (both P<.01). At 3.0 mm, the CCV was increased at 1 day and 1 week (both P<.01) but returned to preoperative levels by 1 month (P=.09). However, the 7.0 mm CCV remained elevated at 1 month (P<.01). There were strong correlations between the change in the 7.0 mm CCV and the estimated fluid used (r = 0.76) and phacoemulsification time (r = 0.61).
  
  
  CONCLUSIONS
  Scheimpflug imaging and OCT underestimated the CCT in normal eyes compared with US pachymetry, with a trend toward thicker measurements in acutely edematous corneas. Although the CCV returned to preoperative values at 1 month, the peripheral cornea remained edematous, possibly because of a correlation with the estimated amount of fluid used and phacoemulsification time.
authors.affiliation: From the Department of Ophthalmology, Boston Medical Center, Boston, Massachusetts, USA.
authors.forename: Melissa M
authors.initials: MM
authors.lastname: Wong
authors.affiliation: From the Department of Ophthalmology, Boston Medical Center, Boston, Massachusetts, USA.
authors.forename: Anita N
authors.initials: AN
authors.lastname: Shukla
authors.affiliation: From the Department of Ophthalmology, Boston Medical Center, Boston, Massachusetts, USA. Electronic address: wmunir@som.umaryland.edu.
authors.forename: Wuqaas M
authors.initials: WM
authors.lastname: Munir
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea / Q000473:pathology*; D015715:Corneal Edema / Q000175:diagnosis* / Q000209:etiology; D063171:Corneal Pachymetry / Q000379:methods; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D010781:Photography / Q000379:methods; D011183:Postoperative Complications; D011446:Prospective Studies; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence / Q000379:methods