title: Intravenous leiomyomatosis: a rare cause of intracardiac mass.
abstract: Intravenous leiomyomatosis is an unusual clinical condition characterized by histologically benign smooth muscle lesions extending from the uterus into pelvic and systemic veins and, more rarely, into the right cardiac chambers. We report the case of a 45-year-old woman who presented with a three-week history of dyspnea on exertion, shortness of breath and fatigue. Echocardiography showed a large mobile mass in the right atrium prolapsing into the right ventricle and extending to the inferior vena cava. A computed tomography scan revealed a large mass extending from the right atrium to the inferior vena cava and through the systemic veins as far as the popliteal veins. A presumptive diagnosis of large thrombus was made; the correct diagnosis of intravenous leiomyomatosis with intracardiac involvement was obtained only after surgical resection and histologic examination.
authors.affiliation: Hospital Garcia de Orta, Almada, Portugal. Electronic address: inesmariarosariocruz@mail.com.
authors.forename: Inês
authors.initials: I
authors.lastname: Cruz
authors.affiliation: Hospital Garcia de Orta, Almada, Portugal.
authors.forename: Isabel
authors.initials: I
authors.lastname: João
authors.affiliation: Hospital Garcia de Orta, Almada, Portugal.
authors.forename: Bruno
authors.initials: B
authors.lastname: Stuart
authors.affiliation: Hospital Garcia de Orta, Almada, Portugal.
authors.forename: Mário
authors.initials: M
authors.lastname: Iala
authors.affiliation: Hospital Garcia de Orta, Almada, Portugal.
authors.forename: Luísa
authors.initials: L
authors.lastname: Bento
authors.affiliation: Hospital Garcia de Orta, Almada, Portugal.
authors.forename: Carlos
authors.initials: C
authors.lastname: Cotrim
authors.affiliation: Hospital de Santa Maria, Lisboa, Portugal.
authors.forename: Angelo
authors.initials: A
authors.lastname: Nobre
authors.affiliation: Hospital Garcia de Orta, Almada, Portugal.
authors.forename: Hélder
authors.initials: H
authors.lastname: Pereira
mesh_terms: D005260:Female; D006325:Heart Atria; D006338:Heart Neoplasms / Q000473:pathology*; D006801:Humans; D018231:Leiomyomatosis / Q000473:pathology*; D008875:Middle Aged; D019043:Vascular Neoplasms / Q000473:pathology*; D014682:Vena Cava, Inferior
keywords: Intracardiac mass; Intravenous leiomyomatosis; Leiomioma uterino; Leiomiomatose intravascular; Massa intra-cardíaca; Uterine leiomyoma