title: Invasive lung cancer staging: influence of CT-guided core needle biopsy on onset of pleural carcinomatosis.
abstract: In lung cancer patients with single peripheral lesions, CT-guided needle biopsies (CTNBs) are common for histological sampling. Recently published studies showed conflicting results for the influence of CTNB on the onset of pleural carcinomatosis (PC). In order to estimate the influence of CTNB on pleural tumor spread, 146 histologically confirmed cases of lung cancer diagnosed by CTNB were retrospectively compared to 112 control lung cancer patients diagnosed by non-CTNB. CTNB was not associated with an earlier onset of PC, identifying CTNB as a safe procedure for minimally invasive lung cancer staging.
authors.affiliation: Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany; Member of the German Center for Lung Research DZL, Translational Lung Research Center Heidelberg, Heidelberg, Germany. Electronic address: paul.flechsig@med.uni-heidelberg.de.
authors.forename: Paul
authors.initials: P
authors.lastname: Flechsig
authors.affiliation: Member of the German Center for Lung Research DZL, Translational Lung Research Center Heidelberg, Heidelberg, Germany; Division of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
authors.forename: Josef
authors.initials: J
authors.lastname: Kunz
authors.affiliation: Member of the German Center for Lung Research DZL, Translational Lung Research Center Heidelberg, Heidelberg, Germany; Division of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
authors.forename: Claus-Peter
authors.initials: CP
authors.lastname: Heussel
authors.affiliation: Member of the German Center for Lung Research DZL, Translational Lung Research Center Heidelberg, Heidelberg, Germany; Division of Oncology, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
authors.forename: Farastuk
authors.initials: F
authors.lastname: Bozorgmehr
authors.affiliation: Member of the German Center for Lung Research DZL, Translational Lung Research Center Heidelberg, Heidelberg, Germany; Department of General Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
authors.forename: Philipp
authors.initials: P
authors.lastname: Schnabel
authors.affiliation: Member of the German Center for Lung Research DZL, Translational Lung Research Center Heidelberg, Heidelberg, Germany; Division of Thoracic Surgery, Thoraxklinik at Heidelberg University, Heidelberg, Germany.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Dienemann
authors.affiliation: Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany; Member of the German Center for Lung Research DZL, Translational Lung Research Center Heidelberg, Heidelberg, Germany.
authors.forename: Hans-Ulrich
authors.initials: HU
authors.lastname: Kauczor
authors.affiliation: Department of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany; Member of the German Center for Lung Research DZL, Translational Lung Research Center Heidelberg, Heidelberg, Germany.
authors.forename: Oliver
authors.initials: O
authors.lastname: Sedlaczek
mesh_terms: D000328:Adult; D000368:Aged; D062005:Biopsy, Large-Core Needle / Q000379:methods; D002277:Carcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
keywords: Biopsy; Computed tomography; Lung cancer; Pleural carcinomatosis; Tumor spread