title: Pectic polysaccharide from the green fruits of Momordica charantia (Karela): structural characterization and study of immunoenhancing and antioxidant properties.
abstract: A water soluble pectic polysaccharide (PS) isolated from the aqueous extract of the green fruits of Momordica charantia contains D-galactose and D-methyl galacturonate in a molar ratio of nearly 1:4. It showed splenocyte, thymocyte as well as macrophage activations. Moreover, it exhibited potent antioxidant activities. On the basis of total acid hydrolysis, methylation analysis, periodate oxidation, and 1D and 2D NMR studies, the structure of the repeating unit of the pectic polysaccharide was established as: [Formula: see text].
authors.affiliation: Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore 721102, West Bengal, India.
authors.forename: Bibhash C
authors.initials: BC
authors.lastname: Panda
authors.affiliation: Department of Chemistry, Panskura Banamali College, Purba Medinipur 721152, West Bengal, India.
authors.forename: Soumitra
authors.initials: S
authors.lastname: Mondal
authors.affiliation: Department of Biotechnology, Indian Institute of Technology (IIT), Kharagpur 721302, West Bengal, India.
authors.forename: K Sanjana P
authors.initials: KS
authors.lastname: Devi
authors.affiliation: Department of Biotechnology, Indian Institute of Technology (IIT), Kharagpur 721302, West Bengal, India.
authors.forename: Tapas K
authors.initials: TK
authors.lastname: Maiti
authors.affiliation: Molecular and Applied Mycology and Plant Pathology Laboratory, Department of Botany, Calcutta University, 35, Ballygunge Circular Road, Kolkata, India.
authors.forename: Somanjana
authors.initials: S
authors.lastname: Khatua
authors.affiliation: Molecular and Applied Mycology and Plant Pathology Laboratory, Department of Botany, Calcutta University, 35, Ballygunge Circular Road, Kolkata, India.
authors.forename: Krishnendu
authors.initials: K
authors.lastname: Acharya
authors.affiliation: Department of Chemistry and Chemical Technology, Vidyasagar University, Midnapore 721102, West Bengal, India. Electronic address: sirajul_1999@yahoo.com.
authors.forename: Syed S
authors.initials: SS
authors.lastname: Islam
mesh_terms: D000276:Adjuvants, Immunologic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D002240:Carbohydrate Sequence; D049109:Cell Proliferation / Q000187:drug effects; D005638:Fruit / Q000737:chemistry*; D017665:Hydroxyl Radical / Q000737:chemistry; D015227:Lipid Peroxidation / Q000187:drug effects; D051379:Mice; D008969:Molecular Sequence Data; D029777:Momordica charantia / Q000737:chemistry*; D010368:Pectins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D013154:Spleen / Q000166:cytology / Q000187:drug effects; D060168:Thymocytes / Q000166:cytology / Q000187:drug effects
chemical_list: D000276:Adjuvants, Immunologic; D000975:Antioxidants; D017665:Hydroxyl Radical; D010368:Pectins
keywords: Antioxidant activities; Immunoactivation; Momordica charantia; NMR studies; Pectic polysaccharide; Structure