title: Workup for proteinuria.
abstract: The kidney has anatomic and physiologic features that prevent protein from reaching the urine. In disease processes, this natural mechanism is disrupted, causing protein to leak into the urine. Proteinuria can be used as a marker for disease and disease progression. The general anatomy of the glomerulus along with preliminary workup to evaluate disease based on history, physical and urinalysis results are reviewed in this article. Examples of commonly encountered diseases in the outpatient setting and relevance of proteinuria in chronic kidney disease along with general complications and treatments are also reviewed.
authors.affiliation: 3200 South University Drive, Fort Lauderdale, FL 33328, USA.
authors.forename: Samuel
authors.initials: S
authors.lastname: Snyder
authors.affiliation: Nephrology Department, Allegheny General Hospital, 4th Floor, 320 East North Avenue, Pittsburgh, PA 15212, USA. Electronic address: jjohn@wpahs.org.
authors.forename: Jones Sam
authors.initials: JS
authors.lastname: John
mesh_terms: D015415:Biomarkers; D003928:Diabetic Nephropathies / Q000150:complications; D004032:Diet; D050171:Dyslipidemias / Q000150:complications / Q000188:drug therapy; D004487:Edema / Q000150:complications / Q000628:therapy; D005921:Glomerulonephritis / Q000150:complications; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy; D007677:Kidney Function Tests; D007678:Kidney Glomerulus / Q000033:anatomy & histology / Q000502:physiology; D011320:Primary Health Care; D011507:Proteinuria / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D051436:Renal Insufficiency, Chronic / Q000150:complications; D012680:Sensitivity and Specificity
chemical_list: D015415:Biomarkers
keywords: Complications with proteinuria; General treatments in patient with proteinuria; Glomerulus in the prevention of proteinuria; Proteinuria; Proteinuria workup