title: Relationship between cardio-ankle vascular index and components of metabolic syndrome in combination with sex and age.
abstract: OBJECTIVE
  The relationship between cardio-ankle vascular index (CAVI) and components of metabolic syndrome (MetS), in addition to age and sex as confounders was explored to verify the characteristics of CAVI.
  
  
  METHODS
  A cross-sectional study was conducted for 144 subjects (108 males and 36 females), aged 31-86 years, who were inhabitants undergoing intensive health checkups. Multiple logistic regression analysis was performed to analyze the association.
  
  
  RESULTS
  MetS was present in 36 of 108 males (33%) and 13 of 36 females (36%). Significant association between CAVI≥9 and male subjects or age was recognized. Although five metabolic components did not show any significant association with CAVI≥9, there was a trend of positive association between CAVI and BMI<25 (p=0.060), high blood pressure (p=0.074) or hypertriglyceridemia (p=0.088).
  
  
  CONCLUSIONS
  Male and age were significantly associated with CAVI≥9. Further study is needed to verify the association between CAVI≥9 and MetS components.
authors.affiliation: Department of Hygiene and Public Health, Nippon Medical School, Japan. Electronic address: kawada@nms.ac.jp.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Kawada
authors.affiliation: Sano City Hospital, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Andou
authors.affiliation: Sano City Hospital, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Fukumitsu
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000842:Ankle / Q000098:blood supply*; D055109:Ankle Brachial Index / Q000379:methods; D001794:Blood Pressure; D003324:Coronary Artery Disease / Q000503:physiopathology / Q000517:prevention & control*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000503:physiopathology*; D008875:Middle Aged; D015203:Reproducibility of Results; D012307:Risk Factors; D012737:Sex Factors; D059289:Vascular Stiffness
keywords: Aging; Cardio-ankle vascular index; Metabolic components; Sex