title: The prodromal phase of psychosis.
abstract: The onset of frank psychosis is usually preceded by a prodromal phase characterized by attenuated psychotic symptoms and a marked deterioration in psychosocial functioning. The last two decades have seen an enormous increase in research work in this area, generating a series of new findings that have significantly advanced out understanding of the neurobiology of psychosis. A key challenge for research in this field is to translate these findings into improvements in the clinical management of the early phase of psychosis.
authors.affiliation: Department of Psychosis Studies, Institute of Psychiatry, King's College London, UK.
authors.forename: Gemma
authors.initials: G
authors.lastname: Modinos
authors.affiliation: Department of Psychosis Studies, Institute of Psychiatry, King's College London, UK. Electronic address: philip.mcguire@kcl.ac.uk.
authors.forename: Philip
authors.initials: P
authors.lastname: McGuire
mesh_terms: D006801:Humans; D009446:Neurobiology; D062706:Prodromal Symptoms; D011618:Psychotic Disorders