title: [AIDS-related primary CNS non-Hodgkin's lymphoma in a patient with previous Epstein-Barr virus panuveitis. A clinico-pathological report].
abstract: METHODS
  Patient with AIDS and Epstein-Barr virus (EBV) uveitis. The PCR of the aqueous and vitreous humor was positive for EBV, and DNA quantification was 56.602×10(6) copies/ml in the vitreous humor, 173,400 copies/ml in the peripheral blood, and negative in the cerebrospinal fluid (CSF). The patient developed a non-Hodgkin's lymphoma (NHL), diagnosed in the autopsy.
  
  
  CONCLUSIONS
  The EBV is a rare cause of uveitis and it may be necessary to perform a quantitative PCR to reach the diagnosis. High amounts of EBV DNA are associated with a greater incidence of NHL.
authors.affiliation: Departamento de Oftalmología, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España. Electronic address: sruizbilbao@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Ruiz-Bilbao
authors.affiliation: Departamento de Microbiología, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España.
authors.forename: À
authors.initials: À
authors.lastname: Hernández
authors.affiliation: Departamento de Oftalmología, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España.
authors.forename: S
authors.initials: S
authors.lastname: Gómez-Sánchez
authors.affiliation: Departamento de Medicina Interna, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Romeu
authors.affiliation: Departamento de Medicina Interna, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España.
authors.forename: L
authors.initials: L
authors.lastname: Llobera L
authors.affiliation: Departamento de Patología, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España.
authors.forename: C
authors.initials: C
authors.lastname: Carrato
authors.affiliation: Departamento de Oftalmología, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España.
authors.forename: R
authors.initials: R
authors.lastname: Anglada
authors.affiliation: Departamento de Oftalmología, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España.
authors.forename: A
authors.initials: A
authors.lastname: Sabala
authors.affiliation: Departamento de Microbiología, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Barcelona, España; CIBER Epidemiología y Salud Pública (CIBERESP), España.
authors.forename: L
authors.initials: L
authors.lastname: Matas
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications; D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000473:pathology* / Q000821:virology; D002825:Chorioretinitis / Q000188:drug therapy / Q000473:pathology; D004279:DNA, Viral / Q000032:analysis; D020031:Epstein-Barr Virus Infections / Q000188:drug therapy / Q000473:pathology*; D017809:Fatal Outcome; D015774:Ganciclovir / Q000627:therapeutic use; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000473:pathology* / Q000821:virology; D016393:Lymphoma, B-Cell / Q000473:pathology* / Q000821:virology; D008297:Male; D015864:Panuveitis / Q000188:drug therapy / Q000473:pathology* / Q000821:virology; D014821:Vitrectomy
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral; D015774:Ganciclovir
keywords: Epstein-Barr virus; HIV; Linfoma no-Hodgkin; Non-Hodgkin lymphoma; PCR; Uveitis; Uveítis; VIH; Virus Epstein-Barr