title: Thinking outside of ABL1 for resistance to tyrosine kinase inhibitors: a perspective of the SEPT9-ABL1 fusion protein.
authors.affiliation: Department of Microbiology and Molecular Genetics; the New Jersey Medical School-Cancer Center; Rutgers Biomedical and Health Sciences, Newark, NJ, USA. Electronic address: th365@njms.rutgers.edu.
authors.forename: Tinghui
authors.initials: T
authors.lastname: Hu
authors.affiliation: Department of Microbiology and Molecular Genetics; the New Jersey Medical School-Cancer Center; Rutgers Biomedical and Health Sciences, Newark, NJ, USA.
authors.forename: Bryan T
authors.initials: BT
authors.lastname: Ciccarelli
mesh_terms: D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics; D015514:Oncogene Proteins, Fusion / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000201:enzymology / Q000235:genetics; D047428:Protein Kinase Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D016315:Proto-Oncogene Proteins c-abl / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D058112:Septins / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism
chemical_list: D015514:Oncogene Proteins, Fusion; D047428:Protein Kinase Inhibitors; D016315:Proto-Oncogene Proteins c-abl; C474315:SEPTIN9 protein, human; D058112:Septins
keywords: ABL1 fusion protein; Resistance; SEPT9-ABL1; Tyrosine kinase inhibitors