title: Thalamic pathways underlying prefrontal cortex-medial temporal lobe oscillatory interactions.
abstract: As focus shifts to large-scale network interactions involved in memory, it is becoming increasingly clear that oscillatory dynamics are critically involved. A number of studies have shown a negative correlation between memory retrieval in alpha and beta power, and a positive correlation between retrieval and theta power. In this opinion article, we suggest three thalamic sub-regions responsible for the coordination of oscillatory activity and the facilitation of memory processes. Specifically, the medial dorsal nucleus is related to changes in beta synchrony, the pulvinar is responsible for alpha synchrony, and the anterior thalamus is related to theta synchrony. These pathways may be modulated via frontal control, and changes in oscillations could be used to track the engagement of underlying memory systems.
authors.affiliation: Department of Psychology and Neuroscience, University of Colorado Boulder, 345 UCB, Boulder, CO, USA. Electronic address: nicholas.ketz@colorado.edu.
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Ketz
authors.affiliation: Radboud University Nijmegen, Donders Institute for Brain, Cognition, and Behaviour, 6500HB, Nijmegen, The Netherlands.
authors.forename: Ole
authors.initials: O
authors.lastname: Jensen
authors.affiliation: Department of Psychology and Neuroscience, University of Colorado Boulder, 345 UCB, Boulder, CO, USA.
authors.forename: Randall C
authors.initials: RC
authors.lastname: O'Reilly
mesh_terms: D000818:Animals; D058256:Brain Waves / Q000502:physiology*; D006801:Humans; D008568:Memory / Q000502:physiology; D008959:Models, Neurological; D009434:Neural Pathways / Q000502:physiology; D017397:Prefrontal Cortex / Q000502:physiology*; D013702:Temporal Lobe / Q000502:physiology*; D013788:Thalamus / Q000502:physiology*