title: [Correlating cup-to-disc ratios measured by HRT-III, SD-OCT and the new color imaging Laguna ONhE procedure].
abstract: OBJECTIVE
  To examine correlations between cup-to-disc (C/D) ratios determined by the new Laguna ONhE (optic nerve hemoglobin) color imaging procedure, spectral domain optical coherence tomography (OCT), confocal scanning laser tomography using Heidelberg retina tomography (HRT), and examining retinal images.
  
  
  METHODS
  C/D ratio measurements were made on 154 eyes of 154 subjects (52 healthy controls, 36 with ocular hypertension and 66 with primary open-angle glaucoma) using the Laguna ONhE, HRT-III (Heidelberg Engineering) and OCT Spectralis (Heidelberg Engineering) instruments and photographs of the optic disc were examined by a blinded observer (experienced glaucoma specialist).
  
  
  RESULTS
  Global intraclass correlation coefficients (ICC) were: 0.379 (95% CI: 0.233-0.508) for Laguna ONhE-HRT, 0.621 (95% CI: 0.513-0.709) for Laguna ONhE-OCT, and 0.558 (95% CI: 0.398-0.678) for the Laguna ONhE-observer, indicating significant agreement in each case (P<.001). The highest ICC was recorded for OCT- observer (0.715; 95% CI: 0.605-0.795).
  
  
  CONCLUSIONS
  C/D ratios measured using the Laguna ONhE procedure correlated well with OCT measurements and retinography measurements made by an experienced observer. Best correlation was observed for OCT versus observer measurements. Agreement was good between the Laguna ONhE, OCT and observer measurements, and was somewhat lower between HRT and the remaining procedures.
authors.affiliation: Servicio de Oftalmología, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, España. Electronic address: ignaciorodriguezu@gmail.com.
authors.forename: I
authors.initials: I
authors.lastname: Rodríguez Uña
authors.affiliation: Servicio de Oftalmología, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, España.
authors.forename: C D
authors.initials: CD
authors.lastname: Méndez Hernández
authors.affiliation: Servicio de Oftalmología, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, España.
authors.forename: F
authors.initials: F
authors.lastname: Sáenz-Francés
authors.affiliation: Servicio de Oftalmología, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, España; Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, Universidad Complutense, Madrid, España; Red Temática de Investigación Cooperativa en Oftalmología (RETICS), Instituto de Salud Carlos III, Madrid, España.
authors.forename: J
authors.initials: J
authors.lastname: García Feijóo
mesh_terms: D000368:Aged; D000886:Anthropometry; D003124:Colorimetry; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007834:Lasers; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis; D009898:Optic Disk / Q000000981:diagnostic imaging*; D009900:Optic Nerve / Q000737:chemistry; D016037:Single-Blind Method; D014054:Tomography / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods
chemical_list: D006454:Hemoglobins
keywords: Cociente excavación/papila; Colorimetry; Colorimetría; Cup/disk ratio; Glaucoma; Morfología; Morphology; Ocular perfusion; Papila; Papilla; Perfusión ocular; Retinografía; Retinography