title: Botulinum toxin a injection to facial and cervical paraspinal muscles in a patient with stiff person syndrome: a case report.
abstract: Stiff person syndrome (SPS) is a rare neurologic disorder of unknown etiology characterized by increased resting muscle tone, progressive rigidity, and stiffness of the axial musculature. We present a case of a 48-year-old male patient with SPS who experienced facial and neck muscle spasms that were uncontrolled with oral medications and the use of an intrathecal baclofen pump. Botulinum toxin A injections into the bilateral masseter and neck paraspinal muscles provided pain relief and spasm control, illustrating the use of botulinum toxin A injections in the small muscles of face and neck in patients with SPS.
authors.affiliation: Department of Physical Medicine and Rehabilitation, University of Kentucky, Lexington, KY(∗).
authors.forename: Praveen N
authors.initials: PN
authors.lastname: Pakeerappa
authors.affiliation: Department of Physical Medicine and Rehabilitation, University of Kentucky, Lexington, KY(†).
authors.forename: Pravardhan
authors.initials: P
authors.lastname: Birthi
authors.affiliation: Department of Physical Medicine and Rehabilitation, University of Kentucky, Lexington, KY(‡). Electronic address: sara.salles@uky.edu.
authors.forename: Sara
authors.initials: S
authors.lastname: Salles
mesh_terms: D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D005152:Facial Muscles; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D009465:Neuromuscular Agents / Q000008:administration & dosage*; D064170:Paraspinal Muscles; D016750:Stiff-Person Syndrome / Q000188:drug therapy*
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A