title: An ancient plant Lawsonia inermis (henna): determination of in vitro antifungal activity against dermatophytes species.
abstract: World is endowed with a rich wealth of medicinal plants. There is a widespread belief that green medicines are healthier and more harmless or safer than synthetic ones. Medicinal plants have been used to cure a number of diseases. The ancient plant Lawsonia inermis or henna is used as medicinal plant because of its attributed strong fungicidal, anti-inflammatory, analgesic, antibacterial, virucidal, antiparasitic, antiamoebiasis, astringent, antihemorrhagic, hypotensive, sedative, anticancer effect and possible anti-sweating properties. In this study, we investigated antifungal activity of L. inermis against clinical dermatophytes species. This study was carried out using 70 clinical isolates of dermatophytes representing six different species; 44 Trichophyton rubrum, 8 Trichophyton mentagrophytes, 6 Microsporum canis, 6 Trichophyton tonsurans, 4 Epidermophyton floccosum, and 2 Trichophyton violaceum. The antifungal activity of L. inermis (henna) was determined by agar diffusion method and henna was used as paste form. Henna paste showed the high antifungal activity against all dermatophytes species (20 to 50mm inhibition zone).
authors.affiliation: Microbiology and Clinical Microbiology Department, Ataturk University Medical Faculties, Erzurum, Turkey.
authors.forename: G S
authors.initials: GS
authors.lastname: Gozubuyuk
authors.affiliation: Microbiology and Clinical Microbiology Department, Ataturk University Medical Faculties, Erzurum, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Aktas
authors.affiliation: Medical Laboratory Department, Ataturk University Health Services Vocational Training School, 25070 Erzurum, Turkey. Electronic address: nimyigit@hotmail.com.
authors.forename: N
authors.initials: N
authors.lastname: Yigit
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D003881:Dermatomycoses / Q000453:epidemiology / Q000382:microbiology; D005260:Female; D006801:Humans; D031564:Lawsonia Plant / Q000737:chemistry*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010936:Plant Extracts / Q000494:pharmacology*; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts
keywords: Antifungal activity; Dermatophyte; Dermatophytes; Henna paste; L’activité antifongique; Pâte de henné