title: Mild rhodium(III)-catalyzed C-H allylation with 4-vinyl-1,3-dioxolan-2-ones: direct and stereoselective synthesis of (E)-allylic alcohols.
abstract: A rhodium(III)-catalyzed C-H direct allylation reaction with 4-vinyl-1,3-dioxolan-2-ones has been developed. The reaction provides a facile and stereoselective access to substituted-(E)-allylic alcohols under mild and redox-neutral reaction conditions. Olefinic C-H activation is applicable, giving multifunctionalized skipped dienes in good yields. Minimal double-bond migration was observed.
authors.affiliation: School of Pharmaceutical Sciences, Sun Yat-sen University , Guangzhou 510006, China.
authors.forename: Shang-Shi
authors.initials: SS
authors.lastname: Zhang
authors.forename: Jia-Qiang
authors.initials: JQ
authors.lastname: Wu
authors.forename: Ye-Xing
authors.initials: YX
authors.lastname: Lao
authors.forename: Xu-Ge
authors.initials: XG
authors.lastname: Liu
authors.forename: Yao
authors.initials: Y
authors.lastname: Liu
authors.forename: Wen-Xin
authors.initials: WX
authors.lastname: Lv
authors.forename: Dong-Hang
authors.initials: DH
authors.lastname: Tan
authors.forename: Yao-Fu
authors.initials: YF
authors.lastname: Zeng
authors.forename: Honggen
authors.initials: H
authors.lastname: Wang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D004148:Dioxolanes / Q000737:chemistry*; D006860:Hydrogen Bonding; D015394:Molecular Structure; D020005:Propanols / Q000138:chemical synthesis* / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D000475:Alkenes; D004148:Dioxolanes; D020005:Propanols; D014753:Vinyl Compounds; C006463:allyl alcohol; D012238:Rhodium; C031133:ethylene carbonate