title: The accuracy of ultrasonography and magnetic resonance imaging for the diagnosis of Morton's neuroma: a systematic review.
abstract: OBJECTIVE
  To determine the accuracy of MRI versus ultrasound for Morton's neuroma.
  
  
  METHODS
  A search was undertaken for clinical studies published in any language in PubMed up to the date of December 2013. Studies assessing the accuracy of the ultrasound or MRI for the diagnosis of Morton's neuroma were included. Data were pooled for meta-analysis. Study selection, data collection, and extraction were performed independently by two authors. Meta-disc 1.4 and Revman 5.2 software were applied for statistical analysis.
  
  
  RESULTS
  The study included 12 studies; 217 patients underwent MRI and 241 underwent ultrasound examinations. There appeared greater diagnostic accuracy for ultrasound than MRI for the diagnosis of Morton's neuroma (ultrasound sensitivity 90%, specificity 88%, positive likelihood ratio 2.77, negative likelihood ratio 0.16 versus MRI sensitivity 93%, specificity 68%, positive likelihood ratio 1.89, negative likelihood ratio 0.19).
  
  
  CONCLUSIONS
  The available evidence suggests that ultrasound can provide better accuracy for the diagnosis of Morton's neuroma than MRI.
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, No.37 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Xu
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, No.37 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan, China.
authors.forename: X
authors.initials: X
authors.lastname: Duan
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, No.37 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan, China.
authors.forename: X
authors.initials: X
authors.lastname: Yu
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, No.37 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan, China.
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Pathology, Chengdu Women's and Children's Central Hospital, No. 1617 Riyue Avenue, Chengdu 610000, Sichuan, China.
authors.forename: X
authors.initials: X
authors.lastname: Dong
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, No.37 Guoxue Alley, Wuhou District, Chengdu 610041, Sichuan, China. Electronic address: xiangzhou15@hotmail.com.
authors.forename: Z
authors.initials: Z
authors.lastname: Xiang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005534:Foot Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009463:Neuroma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D055815:Young Adult