title: Assessment of treatment success and short-term effectiveness using C-arm CT immediately after hepatic chemoembolization of HCC.
abstract: OBJECTIVE
  To investigate semiquantitative analyses based on amount and morphology of iodized oil uptake about non-enhanced C-arm cone-beam CT(C-arm CT) immediately following hepatic chemoembolization of HCC.
  
  
  METHODS
  We retrospectively reviewed 40 C-arm CT images taken immediately following chemoembolization in 29 consecutive patients who underwent hepatic chemoembolization for HCC lesions(n=97). Two radiologists scored iodized oil uptake in the index tumours from Grade 0(complete) to 4(invisible). To describe the morphologic characteristics of uptake, the lesions scored as Grade 1 to 3 were subclassified as ‘defective’ and ‘not-defective’ with respect to uptake. To evaluate the performance of this modality, we performed a receiver operating characteristic curve analysis.
  
  
  RESULTS
  All treated lesions were classified into ‘complete treatment’(n=50) and 'viable HCC'(n=47). Thirty-one lesions were evaluated as Grade 0, two as Grade 4, and the rest (n=64) as between Grades 1 and 3, and the lesions of Grade 3 or 4 were all viable. Of the defective uptake lesions(n=35), 28 lesions were also viable. The areas under the curves of the lesions were 0.827 to 0.860.
  
  
  CONCLUSIONS
  The analysis of C-arm CT based on the amount and morphologic characteristics of iodized oil uptake may be useful to predict the effectiveness of the hepatic chemoembolization of HCC.
authors.forename: Woo Jung
authors.initials: WJ
authors.lastname: Choi
authors.forename: Woo Kyoung
authors.initials: WK
authors.lastname: Jeong
authors.forename: Yongsoo
authors.initials: Y
authors.lastname: Kim
authors.forename: Jinoo
authors.initials: J
authors.lastname: Kim
authors.forename: Soon Young
authors.initials: SY
authors.lastname: Song
authors.forename: Seunghun
authors.initials: S
authors.lastname: Lee
authors.forename: Young Hwan
authors.initials: YH
authors.lastname: Kim
authors.forename: Choong Ki
authors.initials: CK
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019540:Area Under Curve; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D054893:Cone-Beam Computed Tomography; D003287:Contrast Media; D005240:Feasibility Studies; D006801:Humans; D007459:Iodized Oil; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012372:ROC Curve; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media; D007459:Iodized Oil