title: Pediatric sleep-related breathing disorders: advances in imaging and computational modeling.
abstract: We understand now that sleep of sufficient length and quality is required for good health. This is particularly true for infants and children, who have the added physiologic task of growth and development, as compared to their adult counterparts. Sleep-related breathing disorders (SRBDs) are common in childhood and if unrecognized and not treated can result in significant morbidity. For example, children with obstructive sleep apnea (OSA) can exhibit behavioral, mood, and learning difficulties. If left untreated, alterations in the function of the autonomic nervous system and a chronic inflammatory state result, contributing to the risk of heart disease, stroke, glucose intolerance, and hypertension in adulthood.
authors.forename: Sally L
authors.initials: SL
authors.lastname: Davidson Ward
authors.forename: Raouf
authors.initials: R
authors.lastname: Amin
authors.forename: Raanan
authors.initials: R
authors.lastname: Arens
authors.lastname: Zhongping Chen
authors.forename: Stephanie
authors.initials: S
authors.lastname: Davis
authors.forename: Ephraim
authors.initials: E
authors.lastname: Gutmark
authors.forename: Richard
authors.initials: R
authors.lastname: Superfine
authors.forename: Brian
authors.initials: B
authors.lastname: Wong
authors.forename: Carlton
authors.initials: C
authors.lastname: Zdanski
authors.forename: Michael C K
authors.initials: MC
authors.lastname: Khoo
mesh_terms: D002648:Child; D003198:Computer Simulation; D003952:Diagnostic Imaging / Q000379:methods*; D004314:Down Syndrome / Q000503:physiopathology; D004825:Epiglottis / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D009055:Mouth / Q000473:pathology / Q000503:physiopathology; D063766:Pediatric Obesity; D010614:Pharynx / Q000473:pathology / Q000503:physiopathology; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis* / Q000473:pathology