title: [The diet low in fermentable carbohydrates short chain and polyols improves symptoms in patients with functional gastrointestinal disorders in Spain].
abstract: OBJECTIVE
  Successful treatment of patients with irritable bowel syndrome (IBS) often remains elusive. Recent studies in Australia, the United Kingdom and New Zealand have suggested the efficacy of a diet low in fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAPs) in the management of these patients. The aims of this study were to determine whether a diet low in FODMAPs improves symptoms in patients with functional gastrointestinal disorders (FGID) in Spain and to analyze the predictors of a good response.
  
  
  METHODS
  A prospective study was carried out in consecutive patients with FGID type IBS and functioanl abdominal bloating. At inclusion all patients underwent an assessment through a baseline demographic questionnaire of symptoms of anxiety and depression and quality of life. A hydrogen breath test with lactose and fructose was performed and a low FODMAPs diet was indicated for 2 months by expert dietitians. These tests were taken as a reference. A positive response was defined as an improvement of at least 5 points out of a possible 10 in the symptom questionnaire.
  
  
  RESULTS
  We included 30 patients (24 women, 39 [12] years). The response to the low FODMAPs diet was positive in controlling overall symptoms and specific symptoms such as functioanl abdominal bloating, abdominal pain, diarrhea, flatulence, nausea and fatigue in more than 70% of patients (P<.05). By contrast, constipation was controlled in only 48% of patients (P>.05). Adherence to the diet was good in 87% of patients and was a predictor of positive response in the univariate analysis.
  
  
  CONCLUSIONS
  A diet low in FODMAPs is associated with symptom improvement in patients with IBS and functioanl abdominal bloating. Adherence to the diet was a determining factor.
authors.affiliation: Servicio de Aparato Digestivo, Hospital General de Catalunya, Universidad Internacional de Catalunya, Sant Cugat del Vallès, Barcelona, España.
authors.forename: José Wálter
authors.initials: JW
authors.lastname: Huamán
authors.affiliation: Servicio de Endocrinología, Hospital General de Catalunya, Sant Cugat del Vallès, Barcelona, España.
authors.forename: Ana
authors.initials: A
authors.lastname: Felip
authors.affiliation: Servicio de Endocrinología, Hospital General de Catalunya, Sant Cugat del Vallès, Barcelona, España.
authors.forename: Elena
authors.initials: E
authors.lastname: Guedea
authors.affiliation: Servicio de Endocrinología, Hospital General de Catalunya, Sant Cugat del Vallès, Barcelona, España.
authors.forename: Marta
authors.initials: M
authors.lastname: Jansana
authors.affiliation: Departamento de Ciencias Experimentales y de la Salud, Facultad de Ciencias de la Salud y de la Vida, Universitat Pompeu Fabra, Barcelona, España.
authors.forename: Sebastián
authors.initials: S
authors.lastname: Videla
authors.affiliation: Servicio de Aparato Digestivo, Hospital General de Catalunya, Universidad Internacional de Catalunya, Sant Cugat del Vallès, Barcelona, España. Electronic address: esapfra@gmail.com.
authors.forename: Esteban
authors.initials: E
authors.lastname: Saperas
mesh_terms: D000328:Adult; D001944:Breath Tests; D015897:Comorbidity; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005285:Fermentation; D005767:Gastrointestinal Diseases / Q000150:complications / Q000178:diet therapy* / Q000523:psychology; D006801:Humans; D006859:Hydrogen / Q000032:analysis; D008286:Malabsorption Syndromes / Q000178:diet therapy / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009005:Monosaccharides / Q000009:adverse effects; D009844:Oligosaccharides / Q000009:adverse effects; D010342:Patient Acceptance of Health Care; D011108:Polymers / Q000008:administration & dosage / Q000627:therapeutic use*; D011446:Prospective Studies; D011788:Quality of Life; D013030:Spain; D011795:Surveys and Questionnaires; D063189:Symptom Assessment; D016896:Treatment Outcome
chemical_list: D004040:Dietary Carbohydrates; D009005:Monosaccharides; D009844:Oligosaccharides; D011108:Polymers; C024617:polyol; D006859:Hydrogen
keywords: Diet; Dieta; Fermentable carbohydrates and polyols; Hidratos de carbono y polioles fermentables; Irritable bowel syndrome; Síndrome de intestino irritable