title: Precordial QRS amplitude ratio predicts long-term outcome after catheter ablation of electrical storm due to ventricular tachycardias in patients with arrhythmogenic right ventricular cardiomyopathy.
abstract: BACKGROUND
  Radiofrequency catheter ablation is currently considered as the therapeutic option of choice in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) and recurrent ventricular tachycardia (VT).
  
  
  METHODS
  This study intended to assess the long-term outcome of catheter ablation in patients with ARVC and electrical storm. The specific objective was to assess the relationship between precordial QRS amplitude ratio and outcome of catheter ablation in these patients.
  
  
  RESULTS
  Twenty-eight patients (19 men, age 52.3±14.2years) underwent 48 catheter ablation procedures (range 1-6, six epicardial). During a mean follow-up of 18.7±15.1months, 13 patients (46.5%) experienced VT recurrence. Age >50years and ∑QRSmvV1-V3/∑QRSmvV1-V6≤0.48 but not right ventricular size and acute ablation outcome were associated with VT recurrence during the follow up.
  
  
  CONCLUSIONS
  Age >50years and ∑QRSmvV1-V3/∑QRSmvV1-V6≤0.48 predict recurrence of VT after successful radiofrequency catheter ablation of VT in patients with ARVC and electrical storm.
authors.affiliation: Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany. Electronic address: andreas.muessigbrodt@gmail.com.
authors.forename: Andreas
authors.initials: A
authors.lastname: Müssigbrodt
authors.affiliation: Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Borislav
authors.initials: B
authors.lastname: Dinov
authors.affiliation: Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Livio
authors.initials: L
authors.lastname: Bertagnoli
authors.affiliation: Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Philipp
authors.initials: P
authors.lastname: Sommer
authors.affiliation: Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Sergio
authors.initials: S
authors.lastname: Richter
authors.affiliation: Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Ole A
authors.initials: OA
authors.lastname: Breithardt
authors.affiliation: Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Sascha
authors.initials: S
authors.lastname: Rolf
authors.affiliation: Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Bollmann
authors.affiliation: Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Gerhard
authors.initials: G
authors.lastname: Hindricks
authors.affiliation: Department of Electrophysiology, University of Leipzig, Heart Center, Leipzig, Germany.
authors.forename: Arash
authors.initials: A
authors.lastname: Arya
mesh_terms: D000328:Adult; D019571:Arrhythmogenic Right Ventricular Dysplasia / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery*; D017115:Catheter Ablation; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000379:methods; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D017180:Tachycardia, Ventricular / Q000150:complications / Q000175:diagnosis* / Q000601:surgery*; D016896:Treatment Outcome
keywords: 12 Lead ECG; Arrhythmogenic right ventricular cardiomyopathy; Catheter ablation; Electrical storm; Precordial QRS amplitude ratio; Ventricular tachycardia