title: Treatment adherence and health outcomes in MSM with HIV/AIDS: patients enrolled in "one-stop" and standard care clinics in Wuhan China.
abstract: BACKGROUND
  Conducted in Wuhan China, this study examined follow-up and health markers in HIV patients receiving care in two treatment settings. Participants, all men who have sex with men, were followed for 18-24 months.
  
  
  METHODS
  Patients in a "one-stop" service (ACC; N = 89) vs those in standard care clinics (CDC; N = 243) were compared on HIV treatment and retention in care outcomes.
  
  
  RESULTS
  Among patients with CD4 cell count ≦350 cells/µL, the proportion receiving cART did not differ across clinic groups. The ACC was favored across five other indicators: proportion receiving tests for CD4 cell count at the six-month interval (98.2% vs. 79.4%, 95% CI 13.3-24.3, p = 0.000), proportion with HIV suppression for patients receiving cART for 6 months (86.5% vs. 57.1%, 95% CI 14.1-44.7, p = 0.000), proportion with CD4 cell recovery for patients receiving cART for 12 months (55.8% vs. 22.2%, 95% CI 18.5-48.6, p = 0.000), median time from HIV confirmation to first test for CD4 cell count (7 days, 95% CI 4-8 vs. 10 days, 95% CI 9-12, log-rank p = 0.000) and median time from first CD4 cell count ≦350 cells/µL to cART initiation (26 days, 95% CI 16-37 vs. 41.5 days, 95% CI 35-46, log-rank p = 0.031). Clinic groups did not differ on any biomedical indicator at baseline, and no baseline biomedical or demographic variables remained significant in the multivariate analysis. Nonetheless, post-hoc analyses suggest the possibility of self-selection bias.
  
  
  CONCLUSIONS
  Study findings lend preliminary support to a one-stop patient-centered care model that may be useful across various HIV care settings.
authors.affiliation: Wuhan Centers for Disease Control and Prevention, Wuhan, Hubei, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Zhou
authors.affiliation: Wuhan Institute of Dermatovenereology, Wuhan, Hubei, China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhao
authors.affiliation: Wuhan Centers for Disease Control and Prevention, Wuhan, Hubei, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Social Welfare, Luskin School of Public Affairs, University of California Los Angeles, Los Angeles, California, United States of America.
authors.forename: Robert F
authors.initials: RF
authors.lastname: Schilling
authors.affiliation: Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America.
authors.forename: Sheng
authors.initials: S
authors.lastname: Zhou
authors.affiliation: Wuhan Institute of Dermatovenereology, Wuhan, Hubei, China.
authors.forename: Hong-Yan
authors.initials: HY
authors.lastname: Qiu
authors.affiliation: Wuhan Centers for Disease Control and Prevention, Wuhan, Hubei, China.
authors.forename: Nian-Hua
authors.initials: NH
authors.lastname: Xie
authors.affiliation: Wuhan Centers for Disease Control and Prevention, Wuhan, Hubei, China.
authors.forename: Man-Qing
authors.initials: MQ
authors.lastname: Liu
authors.affiliation: Wuhan Institute of Dermatovenereology, Wuhan, Hubei, China.
authors.forename: Han-Sheng
authors.initials: HS
authors.lastname: Dong
authors.affiliation: Wuhan Centers for Disease Control and Prevention, Wuhan, Hubei, China.
authors.forename: Zhong-Zhao
authors.initials: ZZ
authors.lastname: Yao
authors.affiliation: AIDS Care of China, Nanning, Guangxi, China.
authors.forename: Thomas
authors.initials: T
authors.lastname: Cai
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D002681:China; D015658:HIV Infections / Q000188:drug therapy*; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D018802:Patient-Centered Care; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents