title: Hypoglycemia with a large retroperitoneal mass - Case report.
abstract: BACKGROUND
  Retroperitoneal sarcomas have rarely been reported to secrete insulin-growth factor II (IGF-II) and produce an enigmatic hypoglycemia. IGF-II-secreting sarcomas represent an extremely rare subset of soft tissue tumors, and reports are limited to a handful of cases.
  
  
  METHODS
  The authors present the case of hypoglycemia due to an IGF-II-secreting retroperitoneal sarcoma that was successfully treated by complete surgical resection. This report describes the diagnosis and management of this rare syndrome with 1-year follow-up and a review of the literature.
  
  
  CONCLUSIONS
  Steroid and growth hormone therapies also have efficacy to treat this hypoglycemia in some patients. However, outcomes appear better if combined with surgical resection.
  
  
  CONCLUSIONS
  The findings of this case report and review of the literature support a primary role for complete tumor resection to address tumor-induced hypoglycemia.
authors.affiliation: Department of Surgery, Saint Louis University School of Medicine, St. Louis, MO, United States. Electronic address: JPick@SLU.edu.
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Hawasli
authors.affiliation: Department of Surgery, Saint Louis University School of Medicine, St. Louis, MO, United States.
authors.forename: Jacob R
authors.initials: JR
authors.lastname: Hopping
authors.affiliation: Department of Surgery, Saint Louis University School of Medicine, St. Louis, MO, United States.
authors.forename: Eddy C
authors.initials: EC
authors.lastname: Hsueh
keywords: Hypoglycemia; Insulin-like growth factor; Retroperitoneal mass