title: Adenosine activates thermogenic adipocytes.
abstract: Brown or beige fat activation can cause potent anti-obesity and anti-diabetic effects. In a study recently published in Nature, Gnad et al. show that adenosine is a novel activator of brown and beige fat that acts through the A2A receptor.
authors.affiliation: Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
authors.forename: Amy K
authors.initials: AK
authors.lastname: Rines
authors.affiliation: Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
authors.forename: Francisco
authors.initials: F
authors.lastname: Verdeguer
authors.affiliation: Department of Cancer Biology, Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.
authors.forename: Pere
authors.initials: P
authors.lastname: Puigserver
mesh_terms: D000241:Adenosine / Q000378:metabolism*; D017667:Adipocytes / Q000378:metabolism*; D002001:Adipose Tissue, Brown / Q000378:metabolism*; D000818:Animals; D006801:Humans; D008297:Male; D043705:Receptor, Adenosine A2A / Q000378:metabolism*
chemical_list: D043705:Receptor, Adenosine A2A; D000241:Adenosine