title: Y90 selective internal radiation therapy.
abstract: Primary liver malignancies and liver metastases are affecting millions of individuals worldwide. Because of their late and advanced stage presentation, only 10% of patients can receive curative surgical treatment, including transplant or resection. Alternative treatments, such as systemic chemotherapy, ablative therapy, and chemoembolization, have been used with marginal survival benefits. Selective internal radiation therapy (SIRT), also known as radioembolization, is a compelling alternative treatment option for primary and metastatic liver malignancies with a growing body of evidence. In this article, an introduction to SIRT including background, techniques, clinical outcomes, and complications is reviewed.
authors.affiliation: Interventional Radiology, Department of Radiology, UCLA Medical Center, David Geffen School of Medicine, Los Angeles, CA, USA. Electronic address: EdwardLee@mednet.ucla.edu.
authors.forename: Edward W
authors.initials: EW
authors.lastname: Lee
authors.affiliation: Interventional Radiology, Department of Radiology, University of British Columbia Medical Center, Vancouver, British Columbia, Canada.
authors.forename: Avnesh S
authors.initials: AS
authors.lastname: Thakor
authors.affiliation: Interventional Radiology, Department of Radiology, UCLA Medical Center, David Geffen School of Medicine, Los Angeles, CA, USA.
authors.forename: Bashir A
authors.initials: BA
authors.lastname: Tafti
authors.affiliation: Interventional Radiology, Department of Radiology, University of British Columbia Medical Center, Vancouver, British Columbia, Canada.
authors.forename: David M
authors.initials: DM
authors.lastname: Liu
mesh_terms: D001918:Brachytherapy; D015179:Colorectal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008113:Liver Neoplasms / Q000532:radiotherapy* / Q000556:secondary; D015021:Yttrium Radioisotopes / Q000627:therapeutic use*
chemical_list: D015021:Yttrium Radioisotopes
keywords: Liver; Malignancy; Selective internal radiation therapy; Y90