title: Clinical usefulness of double balloon enteroscopy in suspected Crohn's disease: the KASID multi-center trial.
abstract: OBJECTIVE
  The recently developed double balloon enteroscopy (DBE) may be useful to evaluate small bowel lesions in patients with suspected Crohn’s disease (CD). We investigated the findings of DBE, small bowel follow-through and abdominal CT in patients with suspected CD who could not be diagnosed with CD using conventional colonoscopy.
  
  
  METHODS
  Thirty patients (27 males, mean age 32.7±9.27 years) with suspected CD were consecutively enrolled in this study. The main symptoms were abdominal pain, chronic diarrhea, weight loss, obscure bleeding, or anemia. These patients were enrolled from May 2006 to January 2007 at 10 tertiary medical centers participating in the Korean Association for the Study of Intestinal Diseases.
  
  
  RESULTS
  The DBE demonstrated definite CD in 24 patients (80.0%) and suspected findings of CD in six patients. The pathology results obtained by endoscopic biopsies revealed a granuloma in six patients (23.1%). The DBE identified additional findings not detected by radiology studies in 24 patients (80%) although the small bowel followthrough and the abdominal CT revealed the abnormal findings (73.1% and 64%).
  
  
  CONCLUSIONS
  DBE may be a promising alternative and useful technique for patients with suspected CD. DBE provides biopsy sampling and more detailed information than radiology studies.
authors.forename: Hyun Joo
authors.initials: HJ
authors.lastname: Jang
authors.forename: Min Ho
authors.initials: MH
authors.lastname: Choi
authors.forename: Chang Soo
authors.initials: CS
authors.lastname: Eun
authors.forename: Hwang
authors.initials: H
authors.lastname: Choi
authors.forename: Kyu Yong
authors.initials: KY
authors.lastname: Choi
authors.forename: Dong Il
authors.initials: DI
authors.lastname: Park
authors.forename: Jung Ho
authors.initials: JH
authors.lastname: Park
authors.forename: Dong Kyung
authors.initials: DK
authors.lastname: Chang
authors.forename: Jin Oh
authors.initials: JO
authors.lastname: Kim
authors.forename: Bong Min
authors.initials: BM
authors.lastname: Ko
authors.forename: Kyu Chan
authors.initials: KC
authors.lastname: Huh
authors.forename: Jeong Sik
authors.initials: JS
authors.lastname: Byeon
authors.forename: Ki don
authors.initials: Kd
authors.lastname: Choi
authors.forename: Jae Hyun
authors.initials: JH
authors.lastname: Choi
authors.forename: Sung Jae
authors.initials: SJ
authors.lastname: Shin
authors.forename: Sea Hyub
authors.initials: SH
authors.lastname: Kae
authors.forename: Moon Sung
authors.initials: MS
authors.lastname: Lee
mesh_terms: D000328:Adult; D001706:Biopsy; D003113:Colonoscopy; D003424:Crohn Disease / Q000000981:diagnostic imaging / Q000473:pathology*; D058582:Double-Balloon Enteroscopy; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D056910:Republic of Korea; D014057:Tomography, X-Ray Computed; D055815:Young Adult