title: Prevalence of meningococcal meningitis in China from 2005 to 2010.
abstract: BACKGROUND
  We aimed to estimate the prevalence and epidemiologic characteristics of meningococcal meningitis (MM) in mainland China (excluding Taiwan, Hong Kong, and Macau) and to provide reference data for controlling the outbreak and prevalence of MM.
  
  
  METHODS
  Data from the National Notifiable Diseases Registry System and the MM case information reporting system from 2005 to 2010 as well as data from the MM Surveillance System were used.
  
  
  RESULTS
  The morbidity of MM for the whole country was, on average, 0.09 cases per 100,000 (range 0.02 [2010]-0.18 [2005] cases per 100,000) from 2005 to 2010, the incidence rate was highest in the Xinjiang autonomous region (average 0.56 cases per 100,000), and the majority of cases came from Anhui province (average 0.32 cases per 100,000). Morbidity was highest in children under 1 year old (average 0.60 cases per 100,000). The proportion of laboratory-confirmed cases of serogroups A, B, and C were 37.2, 11.5 and 42.7, respectively, from 2005 to 2010.
  
  
  CONCLUSIONS
  The incidence level declined year-to-year in mainland China. Children and students are the most at risk groups. The proportion of serogroup C cases has increased year-to-year, and new cases of serogroup W135 have been found. Controlling the epidemic of serogroup C and preventing outbreaks of serogroup B and W135 represent major future challenges.
authors.affiliation: National Immunization Program Center, Chinese Center for Disease Control and Prevention, Beijing 10050, PR China.
authors.forename: Junhong
authors.initials: J
authors.lastname: Li
authors.affiliation: National Immunization Program Center, Chinese Center for Disease Control and Prevention, Beijing 10050, PR China.
authors.forename: Yixing
authors.initials: Y
authors.lastname: Li
authors.affiliation: National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, PR China.
authors.forename: Zhujun
authors.initials: Z
authors.lastname: Shao
authors.affiliation: National Immunization Program Center, Chinese Center for Disease Control and Prevention, Beijing 10050, PR China.
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.affiliation: National Immunization Program Center, Chinese Center for Disease Control and Prevention, Beijing 10050, PR China.
authors.forename: Zundong
authors.initials: Z
authors.lastname: Yin
authors.affiliation: National Immunization Program Center, Chinese Center for Disease Control and Prevention, Beijing 10050, PR China.
authors.forename: Guijun
authors.initials: G
authors.lastname: Ning
authors.affiliation: National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, PR China.
authors.forename: Li
authors.initials: L
authors.lastname: Xu
authors.affiliation: National Immunization Program Center, Chinese Center for Disease Control and Prevention, Beijing 10050, PR China. Electronic address: nip3@chinacdc.cn.
authors.forename: Huiming
authors.initials: H
authors.lastname: Luo
mesh_terms: D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D062306:Geography, Medical; D049674:History, 21st Century; D006801:Humans; D015994:Incidence; D007223:Infant; D008585:Meningitis, Meningococcal / Q000453:epidemiology* / Q000266:history / Q000517:prevention & control; D022401:Meningococcal Vaccines / Q000276:immunology; D009345:Neisseria meningitidis / Q000145:classification; D011159:Population Surveillance; D015995:Prevalence; D012307:Risk Factors; D012621:Seasons; D065288:Serogroup
chemical_list: D022401:Meningococcal Vaccines
keywords: China.; Epidemiology; Meningococcal meningitis; Prevalence