title: ADAM10 and ADAM17: New players in trastuzumab tesistance.
authors.affiliation: Clinical Research Centre, St. Vincent's University Hospital, Dublin and UCD School of Medicine and Medical Science, Conway Institute, University College Dublin, Dublin, Ireland.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Duffy
authors.affiliation: Department of Medical Oncology, St. Vincent's University Hospital, Dublin, Ireland.
authors.forename: John
authors.initials: J
authors.lastname: Crown
authors.affiliation: Education and Research Centre, St. Vincent's University Hospital, Dublin and UCD School of Medicine and Medical Science, Conway Institute, University College Dublin, Dublin, Ireland.
authors.forename: Maeve
authors.initials: M
authors.lastname: Mullooly
mesh_terms: D051722:ADAM Proteins / Q000378:metabolism*; D000072197:ADAM10 Protein; D053829:Amyloid Precursor Protein Secretases / Q000378:metabolism*; D000818:Animals; D061067:Antibodies, Monoclonal, Humanized / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000201:enzymology*; D005260:Female; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism*; D000068878:Trastuzumab
chemical_list: D051722:ADAM Proteins; D000072197:ADAM10 Protein; D053829:Amyloid Precursor Protein Secretases; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D008565:Membrane Proteins; D018719:Erb-b2 Receptor Tyrosine Kinases; D000068878:Trastuzumab; C508053:ERBB2 protein, human; C491236:ADAM10 protein, human