title: No decreased infection rate when using antibiotic-impregnated cement in primary total joint arthroplasty.
abstract: There has been much debate and controversy about the routine use of antibiotic-impregnated bone cement in primary total joint arthroplasty. The purpose of this study was to undertake a meta-analysis to determine whether the use of antibiotic-impregnated bone cement would reduce the incidence of infection after primary total joint arthroplasty. Of 313 citations identified for screening, 6 trials reporting 26,791 patients were eligible for data extraction and meta-analysis. The authors found no statistically significant difference between antibiotic-impregnated bone cement and plain bone cement in terms of the incidence of infection. The results indicated that the use of antibiotic-impregnated bone cement in primary total joint arthroplasty did not lead to a decrease in the rate of infection.
authors.forename: Zeng
authors.initials: Z
authors.lastname: Yi
authors.forename: Shen
authors.initials: S
authors.lastname: Bin
authors.forename: Yang
authors.initials: Y
authors.lastname: Jing
authors.forename: Zhou
authors.initials: Z
authors.lastname: Zongke
authors.forename: Kang
authors.initials: K
authors.lastname: Pengde
authors.forename: Pei
authors.initials: P
authors.lastname: Fuxing
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D019643:Arthroplasty, Replacement / Q000379:methods*; D001843:Bone Cements; D006801:Humans; D015994:Incidence; D007595:Joint Prosthesis / Q000009:adverse effects*; D016459:Prosthesis-Related Infections / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements