title: Comparison of the anterior capsulotomy edge created by manual capsulorhexis and 2 femtosecond laser platforms: Scanning electron microscopy study.
abstract: OBJECTIVE
  To compare the scanning electron microscopy (SEM) features of the anterior capsule edge created by continuous curvilinear capsulorhexis (CCC) and femtosecond laser-assisted capsulotomy using angular second moment and contrast.
  
  
  METHODS
  King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia.
  
  
  METHODS
  Prospective comparative series.
  
  
  METHODS
  Anterior capsule specimens following CCC (n = 10) or femtosecond laser-assisted capsulotomy using 2 platforms (Lensx, n = 9, and Victus, n = 10) were studied by SEM. Irregularity of the capsule edge was quantified using 2 parameters (angular second moment and contrast) using ImageJ software. The clinical features and laser parameters were correlated with angular second moment and contrast.
  
  
  RESULTS
  By SEM, the femtosecond laser-assisted capsulotomy edge surfaces created by both lasers showed marked irregularity compared with the smooth edge of the CCC. The angular second moment and contrast measures for both lasers differed significantly from those obtained for CCC (P<.001). There was no between-laser difference in angular second moment and contrast measures. The angular second moment showed only a weak negative correlation with increasing laser power, whereas contrast showed a weak positive correlation with increasing power.
  
  
  CONCLUSIONS
  Both laser platforms created an irregular capsulotomy edge. The angular second moment and contrast quantified capsule edge irregularities for further comparisons. These measures could be used to quantify efforts to reduce capsule-edge irregularity from femtosecond laser-lens capsule interaction.
authors.affiliation: From the King Khaled Eye Specialist Hospital (Al Harthi, Al Shahwan, Al Towerki, Behrens, Edward), Riyadh, Kingdom of Saudi Arabia; the Department of Mechanical and Industrial Engineering (Banerjee), University of Illinois at Chicago, Chicago, Illinois, and the Wilmer Eye Institute (Behrens, Edward), Johns Hopkins University, Baltimore, Maryland, USA.
authors.forename: Khaled
authors.initials: K
authors.lastname: Al Harthi
authors.affiliation: From the King Khaled Eye Specialist Hospital (Al Harthi, Al Shahwan, Al Towerki, Behrens, Edward), Riyadh, Kingdom of Saudi Arabia; the Department of Mechanical and Industrial Engineering (Banerjee), University of Illinois at Chicago, Chicago, Illinois, and the Wilmer Eye Institute (Behrens, Edward), Johns Hopkins University, Baltimore, Maryland, USA.
authors.forename: Sami
authors.initials: S
authors.lastname: Al Shahwan
authors.affiliation: From the King Khaled Eye Specialist Hospital (Al Harthi, Al Shahwan, Al Towerki, Behrens, Edward), Riyadh, Kingdom of Saudi Arabia; the Department of Mechanical and Industrial Engineering (Banerjee), University of Illinois at Chicago, Chicago, Illinois, and the Wilmer Eye Institute (Behrens, Edward), Johns Hopkins University, Baltimore, Maryland, USA.
authors.forename: Abdulelah
authors.initials: A
authors.lastname: Al Towerki
authors.affiliation: From the King Khaled Eye Specialist Hospital (Al Harthi, Al Shahwan, Al Towerki, Behrens, Edward), Riyadh, Kingdom of Saudi Arabia; the Department of Mechanical and Industrial Engineering (Banerjee), University of Illinois at Chicago, Chicago, Illinois, and the Wilmer Eye Institute (Behrens, Edward), Johns Hopkins University, Baltimore, Maryland, USA.
authors.forename: P Pat
authors.initials: PP
authors.lastname: Banerjee
authors.affiliation: From the King Khaled Eye Specialist Hospital (Al Harthi, Al Shahwan, Al Towerki, Behrens, Edward), Riyadh, Kingdom of Saudi Arabia; the Department of Mechanical and Industrial Engineering (Banerjee), University of Illinois at Chicago, Chicago, Illinois, and the Wilmer Eye Institute (Behrens, Edward), Johns Hopkins University, Baltimore, Maryland, USA.
authors.forename: Ashley
authors.initials: A
authors.lastname: Behrens
authors.affiliation: From the King Khaled Eye Specialist Hospital (Al Harthi, Al Shahwan, Al Towerki, Behrens, Edward), Riyadh, Kingdom of Saudi Arabia; the Department of Mechanical and Industrial Engineering (Banerjee), University of Illinois at Chicago, Chicago, Illinois, and the Wilmer Eye Institute (Behrens, Edward), Johns Hopkins University, Baltimore, Maryland, USA. Electronic address: dedwar39@jhmi.edu.
authors.forename: Deepak P
authors.initials: DP
authors.lastname: Edward
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D057866:Anterior Capsule of the Lens / Q000601:surgery / Q000648:ultrastructure*; D019923:Capsulorhexis / Q000379:methods*; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D019654:Lens Implantation, Intraocular; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D011446:Prospective Studies