title: Origin and immunoescape of uterine cervical cancer.
abstract: Human papillomavirus associated uterine cervical cancer is an important public health problem since it is classified as the fourth most common cancer in women worldwide with more than 500,000 recorded cases. This review is focused on where and why HPV infection induces cervical cancers and how this virus avoids the host immune response. Immunological therapeutic approaches are also addressed.
authors.affiliation: University of Liège, cellular and molecular immunology, GIGA-Research, 4000 Liège, Belgium.
authors.forename: Dorien
authors.initials: D
authors.lastname: Van Hede
authors.affiliation: University of Liège, cellular and molecular immunology, GIGA-Research, 4000 Liège, Belgium.
authors.forename: Inge
authors.initials: I
authors.lastname: Langers
authors.affiliation: University of Liège, experimental pathology, GIGA-Research, 4000 Liège, Belgium.
authors.forename: Philippe
authors.initials: P
authors.lastname: Delvenne
authors.affiliation: University of Liège, cellular and molecular immunology, GIGA-Research, 4000 Liège, Belgium. Electronic address: n.jacobs@ulg.ac.be.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Jacobs
mesh_terms: D019496:Cancer Vaccines / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007167:Immunotherapy / Q000379:methods / Q000639:trends; D009079:Mucociliary Clearance / Q000502:physiology; D027383:Papillomaviridae / Q000276:immunology / Q000472:pathogenicity / Q000502:physiology; D030361:Papillomavirus Infections / Q000150:complications / Q000276:immunology; D053918:Papillomavirus Vaccines / Q000627:therapeutic use; D019139:Tumor Escape / Q000502:physiology*; D002583:Uterine Cervical Neoplasms / Q000276:immunology* / Q000628:therapy / Q000821:virology*; D002578:Uterine Cervical Dysplasia / Q000276:immunology* / Q000628:therapy / Q000821:virology*
chemical_list: D019496:Cancer Vaccines; D053918:Papillomavirus Vaccines