title: Identification and characterization of genetic structures coding for carbapenemases in Enterobacteria from Central Greece.
abstract: The dissemination of carbapenemases among different species of Enterobacteriaceae was investigated in the University Hospital of Larissa, Central Greece. The presence of the isoform (Tn4401a) of the transponson carrying blaKPC-2 and 5 divergent blaVIM-carrying class I integrons, including a novel structure, suggests interspecies transfer of these mobile elements and underscores their ongoing evolution.
authors.affiliation: Department of Microbiology, University Hospital of Larissa, Larissa, Greece.
authors.forename: Angeliki
authors.initials: A
authors.lastname: Mavroidi
authors.affiliation: Department of Microbiology, University Hospital of Larissa, Larissa, Greece.
authors.forename: Apostolos
authors.initials: A
authors.lastname: Liakopoulos
authors.affiliation: Department of Microbiology, University Hospital of Larissa, Larissa, Greece.
authors.forename: Stiliani
authors.initials: S
authors.lastname: Sarrou
authors.affiliation: Laboratory of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.
authors.forename: Vivi
authors.initials: V
authors.lastname: Miriagou
authors.affiliation: Department of Microbiology, University Hospital of Larissa, Larissa, Greece; Department of Microbiology, Medical School, University of Thessaly, Larissa, Greece. Electronic address: petinaki@med.uth.gr.
authors.forename: Efthymia
authors.initials: E
authors.lastname: Petinaki
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D004251:DNA Transposable Elements; D024881:Drug Resistance, Bacterial; D024901:Drug Resistance, Multiple, Bacterial; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000235:genetics* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000382:microbiology; D006115:Greece; D006761:Hospitals; D006801:Humans; D032023:Integrons; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D004251:DNA Transposable Elements; D001618:beta-Lactamases; C063912:carbapenemase
keywords: Carbapenemases; Enterobacteriaceae; Genetic elements; Greece