title: Oral manifestations of allergic, infectious, and immune-mediated disease.
abstract: Patients often have oral symptoms, and physicians frequently identify lesions during routine oral examination. Being able to associate these concerns and findings with systemic disease is important to providing effective management of these conditions. This review summarizes the etiology, presentation, and treatment of many oral lesions associated with systemic diseases and infections. The primary focus was on lesions associated with allergic, infectious, and immune-mediated disease; however, other common concerns are addressed as well as lesions that may be misinterpreted as disease and how to address unknown lesions.
authors.affiliation: Division of Allergy and Clinical Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla. Electronic address: gcowan@health.usf.edu.
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Cowan
authors.affiliation: Division of Allergy and Clinical Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, Tampa, Fla; Division of Allergy and Clinical Immunology, Department of Internal Medicine, James A. Haley Veterans' Hospital, Tampa, Fla.
authors.forename: Richard F
authors.initials: RF
authors.lastname: Lockey
mesh_terms: D003141:Communicable Diseases / Q000150:complications / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D006801:Humans; D006967:Hypersensitivity / Q000150:complications / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D007154:Immune System Diseases / Q000150:complications / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D009059:Mouth Diseases / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D011237:Predictive Value of Tests; D012307:Risk Factors; D016896:Treatment Outcome
keywords: Aphthous; Burning; Candida; Carcinoma; Caries; Dental; Drug reaction; Gingiva; Herpes; Human immunodeficiency virus; Human papilloma virus; Infections; Leukoplakia; Lichen planus; Mucocele; Necrosis; Neoplasm; Stomatitis; Syphilis; Ulceration; Varicella; Wart; Xerostomia