title: Chondrosarcoma of the nasal septum.
abstract: Chondrosarcomas are non-epithelial malignant, slow growing tumors that usually involve pelvis, ribs, and long bones of extremities, scapula and sternum. Median age at diagnosis for head and neck chondrosarcomas is in the fourth decade. The etiopathogenesis of chondrosarcomas remains unknown. Treatment of choice is surgical, with adjuvant therapy having a limited role. In fact, radiation therapy and chemotherapy are reserved for residual or recurrent disease and palliation. As for surgery, several surgical procedures have been described. Recently, endoscopic surgery has allowed for the successful and less invasive treatment of inverting papillomas and even nasopharyngeal angiofibromas, lesions previously requiring extended external approaches. The aim of this paper was to present a case of nasal septal chondrosarcoma that was successfully treated with endoscopic surgery and radiation adjuvant therapy.
authors.affiliation: Division of Otolaryngology, Pinerolo and Rivoli Hospitals, ASL TO3, Pinerolo, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Magnano
authors.forename: Paolo
authors.initials: P
authors.lastname: Boffano
authors.forename: Giacomo
authors.initials: G
authors.lastname: Machetta
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Garibaldi
authors.forename: Elena
authors.initials: E
authors.lastname: Delmastro
authors.forename: Pietro
authors.initials: P
authors.lastname: Gabriele
mesh_terms: D000328:Adult; D002813:Chondrosarcoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D004724:Endoscopy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009300:Nasal Septum / Q000473:pathology* / Q000601:surgery; D009669:Nose Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D018714:Radiotherapy, Adjuvant; D050397:Radiotherapy, Intensity-Modulated