title: Connective tissue disorders associated with vasculitis and vaso-occlusive disease of the hand.
abstract: Hand ischemia caused by vasculitis is a secondary finding in many autoimmune processes. Many of these autoimmune diseases are managed primarily with medications that can prevent the development of occlusive disease, tissue ischemia, and tissue loss. Unfortunately several disease conditions can be recalcitrant to medical management and can result in ischemic changes within the hand, which may require operative intervention. This article briefly reviews the major connective tissue disorders associated with vasculitis and vaso-occlusive disease of the hand, including scleroderma, lupus, and Buerger disease, and their surgical treatment.
authors.affiliation: Division of Plastic Surgery, University of Pennsylvania Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA.
authors.forename: Brett
authors.initials: B
authors.lastname: Michelotti
authors.affiliation: Department of Orthopedics and Division of Plastic Surgery, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
authors.forename: Marco
authors.initials: M
authors.lastname: Rizzo
authors.affiliation: Department of Orthopedics and Division of Plastic Surgery, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. Electronic address: Moran.steven@mayo.edu.
authors.forename: Steven L
authors.initials: SL
authors.lastname: Moran
mesh_terms: D001157:Arterial Occlusive Diseases / Q000209:etiology* / Q000503:physiopathology; D003240:Connective Tissue Diseases / Q000150:complications* / Q000503:physiopathology; D006225:Hand / Q000098:blood supply* / Q000601:surgery; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000503:physiopathology; D012595:Scleroderma, Systemic / Q000150:complications / Q000503:physiopathology; D013919:Thromboangiitis Obliterans / Q000150:complications / Q000503:physiopathology; D014657:Vasculitis / Q000209:etiology* / Q000601:surgery
keywords: Buerger disease; Hand ischemia; Hand vasculitis; Lupus; Scleroderma