title: Corneal thickness of eyes with unilateral age-related macular degeneration.
abstract: OBJECTIVE
  To compare the central corneal thicknesses (CCT), peripheral corneal thicknesses, and corneal volumes (CV) of the 2 eyes of patients with unilateral age-related macular degeneration (AMD).
  
  
  METHODS
  Twenty patients who were diagnosed with unilateral AMD were included in this prospective study for the purpose of making comparison between the diseased and healthy eyes. Optical coherence tomography and fundus fluorescein angiography imaging were applied to all patients in order to confirm and reveal the presence of unilateral AMD. Then, the measurements of CCT, peripheral corneal thickness measured 4 mm distant from the center of the cornea (4 mm CT), and CV of each eye of these patients were obtained through the rotating Scheimpflug corneal topographer.
  
  
  RESULTS
  Wilcoxon signed-rank test did not demonstrate a statistically significant difference between the 2 eyes of patients with unilateral AMD when we compared the CCT and CV of diseased and healthy eyes (p>0.05). However, 4 mm CT of the diseased eyes of these patients were statistically significantly thicker than the healthy eyes (p<0.05).
  
  
  CONCLUSIONS
  The significant difference in terms of 4 mm CT between the diseased and healthy eyes of patients with unilateral AMD may demonstrate the possible effect of peripheral corneal thickness on the development of AMD.
authors.affiliation: Department of Ophthalmology, Canakkale Onsekiz Mart University School of Medicine, Canakkale - Turkey.
authors.forename: Sedat
authors.initials: S
authors.lastname: Arikan
authors.forename: Ismail
authors.initials: I
authors.lastname: Ersan
authors.forename: Selcuk
authors.initials: S
authors.lastname: Kara
authors.forename: Baran
authors.initials: B
authors.lastname: Gencer
authors.forename: Safak
authors.initials: S
authors.lastname: Korkmaz
authors.forename: Azer Sara
authors.initials: AS
authors.lastname: Vural
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011446:Prospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods; D057135:Wet Macular Degeneration / Q000150:complications* / Q000175:diagnosis