title: Caffeine intoxication successfully treated by hemoperfusion and hemodialysis.
abstract: Caffeine is an easily available drug which is generally regarded as being safe. However, it can lead to a lethal outcome in severe cases of caffeine intoxication. We herein report a case of a 32-year-old man who ingested approximately 15.6 g of caffeine in a suicide attempt. He suffered from sustained ventricular tachycardia despite conservative treatment. Therefore, we performed a combined therapy of hemoperfusion and hemodialysis which resulted in rapid improvement of the patient's ventricular tachycardia as well as a reduction of the patient's plasma caffeine level. To the best of our knowledge, this combination has not been previously reported to treat caffeine intoxication.
authors.affiliation: Renal Division, Department of Internal Medicine, Iwata City Hospital, Japan.
authors.forename: Sayaka
authors.initials: S
authors.lastname: Ishigaki
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Fukasawa
authors.forename: Naoko
authors.initials: N
authors.lastname: Kinoshita-Katahashi
authors.forename: Hideo
authors.initials: H
authors.lastname: Yasuda
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Kumagai
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Furuya
mesh_terms: D000328:Adult; D002110:Caffeine / Q000506:poisoning*; D000697:Central Nervous System Stimulants / Q000506:poisoning*; D006464:Hemoperfusion / Q000379:methods; D006801:Humans; D008297:Male; D006435:Renal Dialysis / Q000379:methods; D012559:Schizophrenia / Q000150:complications*; D013406:Suicide, Attempted / Q000523:psychology*; D017180:Tachycardia, Ventricular / Q000139:chemically induced* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000697:Central Nervous System Stimulants; D002110:Caffeine