title: Balloon-assisted enteroscopy in portal hypertensive enteropathy.
abstract: OBJECTIVE
  Balloon-assisted enteroscopy (BAE) provides higher-resolution of imaging and allows both diagnosis and treatment in the small intestine. However, the role of BAE in portal hypertensive enteropathy (PHE) is not clear. The purpose of this study is to define BAE findings and its utility in patients with PHE.
  
  
  METHODS
  This study included 20 cirrhotic patients with PHE and 20 control patients, matched by age and gender, who underwent BAE. The indications were to investigate the cause of obscure gastrointestinal bleeding and to achieve a diagnosis in patients with abnormal video capsule endoscopy and/ or abnormal radiological imaging. We evaluated the diagnostic yield and safety of BAE in PHE.
  
  
  RESULTS
  BAE revealed significantly abnormal small bowel mucosa including angiodysplasia-like lesions, friability, edema, erythema, and punctate hemorrhage in PHE. There was a significantly higher prevalence of small bowel angiodysplasia- like lesions (65%) in the cirrhotic patients as compared with that (10%) in the controls (p = 0.01). Among the patients with small bowel angiodysplasialike lesions (65%), seven patients (35%) exhibited a diffuse pattern, which was not found in the control group (p = 0.008).
  
  
  CONCLUSIONS
  Our study has shown that small bowel angiodysplasia-like lesion, particularly, the diffuse form of the lesion, is the dominant mucosal abnormality in PHE.
authors.forename: Chung-Jyi
authors.initials: CJ
authors.lastname: Tsai
authors.forename: Madhusudhan R
authors.initials: MR
authors.lastname: Sanaka
authors.forename: K V Narayanan
authors.initials: KV
authors.lastname: Menon
authors.forename: John J
authors.initials: JJ
authors.lastname: Vargo
mesh_terms: D000368:Aged; D016888:Angiodysplasia / Q000209:etiology / Q000473:pathology*; D058582:Double-Balloon Enteroscopy; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000473:pathology*; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology*; D007413:Intestinal Mucosa / Q000473:pathology*; D007421:Intestine, Small / Q000473:pathology*; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012042:Registries; D012189:Retrospective Studies; D016896:Treatment Outcome