title: Nanoencapsulated and microencapsulated SERS platforms for biomedical analysis.
abstract: The problems of layer-by-layer-based surface enhancement Raman scattering (SERS)-sensor application for pharmaceutical analysis were discussed. Layer-by-layer (LbL) method allows fabrication of encapsulated SERS platforms with high reproducibility of enhancement factor and increased signal/noise ratio of Raman scattering. LbL encapsulation approach opens an avenue to implement a novel type of theranostic systems combining SERS based sensing and drug delivery in one entity. The area of encapsulation development toward smart multifunctional theranostic systems could bring benefits for personalized medicine and should minimize costs and resources at preclinical and clinical study in pharmacology while testing new bioactive compounds.
authors.affiliation: Saratov State University, Astrakhanskaya Street 83, Saratov 410012, Russia.
authors.forename: Inna Y
authors.initials: IY
authors.lastname: Stetciura
authors.affiliation: Saratov State University, Astrakhanskaya Street 83, Saratov 410012, Russia.
authors.forename: Alexey V
authors.initials: AV
authors.lastname: Markin
authors.affiliation: Saratov State University, Astrakhanskaya Street 83, Saratov 410012, Russia.
authors.forename: Daniil N
authors.initials: DN
authors.lastname: Bratashov
authors.affiliation: School of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom.
authors.forename: Gleb B
authors.initials: GB
authors.lastname: Sukhorukov
authors.affiliation: Saratov State University, Astrakhanskaya Street 83, Saratov 410012, Russia. Electronic address: gorinda@mail.ru.
authors.forename: Dmitry A
authors.initials: DA
authors.lastname: Gorin
mesh_terms: D000818:Animals; D004339:Drug Compounding; D016503:Drug Delivery Systems; D006801:Humans; D049329:Nanostructures / Q000737:chemistry* / Q000627:therapeutic use; D013059:Spectrum Analysis, Raman