title: Normalization of low-density lipoprotein receptor expression in receptor defective homozygous familial hypercholesterolemia by inhibition of PCSK9 with alirocumab.
authors.forename: Gilles
authors.initials: G
authors.lastname: Lambert
authors.forename: Mathias
authors.initials: M
authors.lastname: Chatelais
authors.forename: Francine
authors.initials: F
authors.lastname: Petrides
authors.forename: Maxime
authors.initials: M
authors.lastname: Passard
authors.forename: Aurélie
authors.initials: A
authors.lastname: Thedrez
authors.forename: Kerry-Anne
authors.initials: KA
authors.lastname: Rye
authors.forename: Uwe
authors.initials: U
authors.lastname: Schwahn
authors.forename: Viktoria
authors.initials: V
authors.lastname: Gusarova
authors.forename: Dirk J
authors.initials: DJ
authors.lastname: Blom
authors.forename: William
authors.initials: W
authors.lastname: Sasiela
authors.forename: A David
authors.initials: AD
authors.lastname: Marais
mesh_terms: D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D061067:Antibodies, Monoclonal, Humanized; D002478:Cells, Cultured; D005347:Fibroblasts / Q000378:metabolism; D005434:Flow Cytometry; D006720:Homozygote; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology; D006938:Hyperlipoproteinemia Type II / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D008148:Lovastatin / Q000031:analogs & derivatives / Q000494:pharmacology; D000071449:Proprotein Convertase 9; D043484:Proprotein Convertases / Q000037:antagonists & inhibitors*; D011973:Receptors, LDL / Q000235:genetics / Q000378:metabolism*; D012697:Serine Endopeptidases
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011973:Receptors, LDL; C012258:mevastatin; D008148:Lovastatin; C472125:PCSK9 protein, human; D000071449:Proprotein Convertase 9; D043484:Proprotein Convertases; D012697:Serine Endopeptidases; C571059:alirocumab