title: Guinea pig models of asthma.
abstract: Described in this unit are methods for establishing guinea pig models of asthma. Sufficient detail is provided to enable investigators to study bronchoconstriction, cough, airway hyperresponsiveness, inflammation, and remodeling.
authors.affiliation: School of Biomedical Sciences, University of Queensland, St Lucia, Australia.
authors.forename: Alice E
authors.initials: AE
authors.lastname: McGovern
authors.affiliation: School of Biomedical Sciences, University of Queensland, St Lucia, Australia.
authors.forename: Stuart B
authors.initials: SB
authors.lastname: Mazzone
mesh_terms: D056151:Airway Remodeling / Q000187:drug effects / Q000502:physiology; D000485:Allergens / Q000494:pharmacology; D000771:Anesthesia, Intravenous; D000818:Animals; D001249:Asthma / Q000503:physiopathology; D016084:Bronchoconstriction / Q000187:drug effects / Q000502:physiology; D003371:Cough / Q000503:physiopathology; D004195:Disease Models, Animal; D006168:Guinea Pigs; D008168:Lung / Q000503:physiopathology; D008297:Male; D012121:Respiration, Artificial; D012130:Respiratory Hypersensitivity / Q000139:chemically induced; D014132:Trachea / Q000503:physiopathology
chemical_list: D000485:Allergens
keywords: bronchospasm; cough; hyperresponsiveness; inflammation; remodeling