title: Aspirin-triggered 15-epi-lipoxin A₄ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation.
authors.affiliation: Translational Cardiology, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Marcelo H
authors.initials: MH
authors.lastname: Petri
authors.affiliation: Translational Cardiology, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Andrés
authors.initials: A
authors.lastname: Laguna-Fernandez
authors.affiliation: Vascular Surgery, Center for Molecular Medicine, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Chi-Nan
authors.initials: CN
authors.lastname: Tseng
authors.affiliation: Vascular Surgery, Center for Molecular Medicine, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Ulf
authors.initials: U
authors.lastname: Hedin
authors.affiliation: William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom.
authors.forename: Mauro
authors.initials: M
authors.lastname: Perretti
authors.affiliation: Translational Cardiology, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden. Electronic address: Magnus.Back@ki.se.
authors.forename: Magnus
authors.initials: M
authors.lastname: Bäck
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology / Q000627:therapeutic use; D001241:Aspirin / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D006965:Hyperplasia / Q000378:metabolism* / Q000517:prevention & control*; D044045:Lipoxins / Q000494:pharmacology* / Q000627:therapeutic use; D051379:Mice; D018345:Mice, Knockout; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000378:metabolism / Q000473:pathology*; D032389:Myocytes, Smooth Muscle / Q000187:drug effects / Q000378:metabolism / Q000473:pathology*; D044042:Receptors, Formyl Peptide / Q000172:deficiency*; D017539:Tunica Intima / Q000187:drug effects / Q000473:pathology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D044045:Lipoxins; D044042:Receptors, Formyl Peptide; C481578:formyl peptide receptor 2, mouse; C040527:lipoxin A4; D001241:Aspirin
keywords: Intimal hyperplasia; Lipoxin; Resolution of inflammation; Smooth muscle cells