title: Co-circulation of soricid- and talpid-borne hantaviruses in Poland.
abstract: Previously, we reported the discovery of a genetically distinct hantavirus, designated Boginia virus (BOGV), in the Eurasian water shrew (Neomys fodiens), as well as the detection of Seewis virus (SWSV) in the Eurasian common shrew (Sorex araneus), in central Poland. In this expanded study of 133 shrews and 69 moles captured during 2010-2013 in central and southeastern Poland, we demonstrate the co-circulation of BOGV in the Eurasian water shrew and SWSV in the Eurasian common shrew, Eurasian pygmy shrew (Sorex minutus) and Mediterranean water shrew (Neomys anomalus). In addition, we found high prevalence of Nova virus (NVAV) infection in the European mole (Talpa europaea), with evidence of NVAV RNA in heart, lung, liver, kidney, spleen and intestine. The nucleotide and amino acid sequence variation of the L segment among the SWSV strains was 0-18.8% and 0-5.4%, respectively. And for the 38 NVAV strains from European moles captured in Huta Dłutowska, the L-segment genetic similarity ranged from 94.1%-100% at the nucleotide level and 96.3%-100% at the amino acid level. Phylogenetic analyses showed geographic-specific lineages of SWSV and NVAV in Poland, not unlike that of rodent-borne hantaviruses, suggesting long-standing host-specific adaptation. The co-circulation and distribution of BOGV, SWSV and NVAV in Poland parallels findings of multiple hantavirus species co-existing in their respective rodent reservoir species elsewhere in Europe. Also, the detection of SWSV in three syntopic shrew species resembles spill over events observed among some rodent-borne hantaviruses.
authors.affiliation: Department of Pediatrics, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
authors.forename: Se Hun
authors.initials: SH
authors.lastname: Gu
authors.affiliation: Department of Teacher Training and Biodiversity Studies, Faculty of Biology and Environmental Protection, University of Łódź, S. Banacha Street 1/3, 90-237 Łódź, Poland.
authors.forename: Janusz
authors.initials: J
authors.lastname: Hejduk
authors.affiliation: Department of Teacher Training and Biodiversity Studies, Faculty of Biology and Environmental Protection, University of Łódź, S. Banacha Street 1/3, 90-237 Łódź, Poland.
authors.forename: Janusz
authors.initials: J
authors.lastname: Markowski
authors.affiliation: Department of Pediatrics, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA.
authors.forename: Hae Ji
authors.initials: HJ
authors.lastname: Kang
authors.affiliation: Department of Experimental Zoology and Evolutionary Biology, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland.
authors.forename: Marcin
authors.initials: M
authors.lastname: Markowski
authors.affiliation: Department of Algology and Mycology, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Połatyńska
authors.affiliation: Department of Molecular Pathology and Neuropathology, Medical University of Łódź, Czechoslowacka Street 8/10, 92-216 Łódź, Poland.
authors.forename: Beata
authors.initials: B
authors.lastname: Sikorska
authors.affiliation: Department of Molecular Pathology and Neuropathology, Medical University of Łódź, Czechoslowacka Street 8/10, 92-216 Łódź, Poland.
authors.forename: Paweł P
authors.initials: PP
authors.lastname: Liberski
authors.affiliation: Department of Pediatrics, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USA. Electronic address: ryanagih@hawaii.edu.
authors.forename: Richard
authors.initials: R
authors.lastname: Yanagihara
mesh_terms: D000818:Animals; D006476:Orthohantavirus / Q000145:classification* / Q000235:genetics*; D018778:Hantavirus Infections / Q000662:veterinary* / Q000821:virology*; D008971:Moles / Q000821:virology*; D010802:Phylogeny; D011044:Poland; D012788:Shrews / Q000821:virology*; D014018:Tissue Distribution
keywords: Hantavirus; Neomys; Phylogeny; Poland; Sorex; Talpa