title: Does CircuLite Synergy assist device as partial ventricular support have a place in modern management of advanced heart failure?
abstract: The discrepancy between the number of patients on the waiting list and available donor hearts has led to the successful development of left ventricular assist devices (LVAD) as a bridge to transplantation. The conventional LVADs are designed to provide full hemodynamic support for the end-stage failing heart. However, full-support LVAD implantation requires major surgery, sternotomy and cardiopulmonary bypass in majority of cases. The Synergy Micro-pump is the smallest implantable LVAD and provides partial flow support up to 3 l/min. It was shown that early intervention with this device can provide substantial benefits to patients with severe heart failure not yet sick enough for a full-support LVAD. Due the small dimensions it can be implanted without cardiopulmonary bypass or a sternotomy. The purpose of this article is to review the clinical use of the Synergy Micro-pump as partial hemodynamic support.
authors.affiliation: Department of Cardiothoracic Transplantation and Mechanical support, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
authors.forename: Prashant N
authors.initials: PN
authors.lastname: Mohite
authors.forename: Anton
authors.initials: A
authors.lastname: Sabashnikov
authors.forename: Andre Ruediger
authors.initials: AR
authors.lastname: Simon
authors.forename: Alexander
authors.initials: A
authors.lastname: Weymann
authors.forename: Nikhil Prakash
authors.initials: NP
authors.lastname: Patil
authors.forename: Bernhard
authors.initials: B
authors.lastname: Unsoeld
authors.forename: Christian
authors.initials: C
authors.lastname: Bireta
authors.forename: Aron Frederik
authors.initials: AF
authors.lastname: Popov
mesh_terms: D002315:Cardiopulmonary Bypass / Q000379:methods; D006333:Heart Failure / Q000503:physiopathology* / Q000628:therapy*; D006352:Heart Ventricles / Q000503:physiopathology*; D006353:Heart-Assist Devices; D006801:Humans; D019919:Prosthesis Implantation / Q000379:methods
keywords: LVAD; circulate; partial support device; synergy