title: Efficient lactulose production from cheese whey using sodium carbonate.
abstract: An economical method of lactulose production from cheese whey was developed using sodium carbonate (Na2CO3). Three parameters such as temperature, reaction time, and Na2CO3 concentration were identified as experimental factors, and yield was selected as a response parameter. The experimental factors were optimised employing Response Surface Methodology (RSM). Maximum yield of 29.6% was obtained at reaction time of 20.41 min, Na2CO3 of 0.51% at 90 °C. To overcome this limited lactulose yield, due to the conversion of lactulose to galactose, fed batch system was applied using dried cheese whey as lactose source. By this system, limit was broken, and 15.8 g/L of lactulose is produced in hour.
authors.affiliation: Department of Civil and Environmental Engineering, KAIST, 373-1, Guseong-dong, Yuseong-gu, Daejeon 305-701, Republic of Korea.
authors.forename: Yeong Hwan
authors.initials: YH
authors.lastname: Seo
authors.affiliation: Department of Chemical and Biomolecular Engineering, KAIST, 373-1, Guseong-dong, Yuseong-gu, Daejeon 305-701, Republic of Korea.
authors.forename: Gwon Woo
authors.initials: GW
authors.lastname: Park
authors.affiliation: Department of Civil and Environmental Engineering, KAIST, 373-1, Guseong-dong, Yuseong-gu, Daejeon 305-701, Republic of Korea. Electronic address: hanj2@kaist.ac.kr.
authors.forename: Jong-In
authors.initials: JI
authors.lastname: Han
mesh_terms: D002254:Carbonates / Q000737:chemistry*; D002611:Cheese / Q000032:analysis*; D005690:Galactose / Q000737:chemistry; D007785:Lactose / Q000737:chemistry; D007792:Lactulose / Q000737:chemistry*; D013696:Temperature
chemical_list: D002254:Carbonates; C005686:sodium carbonate; D007792:Lactulose; D007785:Lactose; D005690:Galactose
keywords: Cheese whey; Lactulose; Sodium carbonate