title: Ankylosing spondylitis: correlations between clinical and MRI indices of sacroiliitis activity.
abstract: OBJECTIVE
  To analyse the correlations between clinical and MRI sacroiliitis activity indices in ankylosing spondylitis (AS).
  
  
  METHODS
  Sixteen normal volunteers and 52 patients were enrolled. The clinical AS activity indices included the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) score, serum high-sensitivity C-reactive protein, and erythrocyte sedimentation rate. The MRI sacroiliitis activity indices included apparent diffusion coefficient (ADC) values of bone and the Spondyloarthritis Research Consortium of Canada (SPARCC) score.
  
  
  RESULTS
  The mean SPARCC score of the control group was 0 and of the AS group was 9.9 ± 9.1 (range 0-36). The mean ADC value of the AS group was statistically significantly higher than that of the control group (49.7 ± 20.2 × 10(-5)mm(2)/s versus 38.9 ± 5.3 × 10(-5)mm(2)/s, p < 0.05). The BASDAI score showed a statistically significant correlation with the SPARCC score (r = 0.685, p < 0.05) and with ADC values (r = 0.329, p < 0.05). ADC values correlated with the SPARCC score (r = 0.390, p < 0.05).
  
  
  CONCLUSIONS
  ADC values and the SPARCC index may be useful activity indices in AS.
authors.affiliation: Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095, Jiefang Road, Wuhan City, Hubei Province 430030, China.
authors.forename: P
authors.initials: P
authors.lastname: Zhang
authors.affiliation: Department of Radiology, Xianning Central Hospital, Hubei University of Science and Technology, Hubei Province, China.
authors.forename: K
authors.initials: K
authors.lastname: Yu
authors.affiliation: Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095, Jiefang Road, Wuhan City, Hubei Province 430030, China.
authors.forename: R
authors.initials: R
authors.lastname: Guo
authors.affiliation: Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095, Jiefang Road, Wuhan City, Hubei Province 430030, China.
authors.forename: S
authors.initials: S
authors.lastname: Shah
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: J N
authors.initials: JN
authors.lastname: Morelli
authors.affiliation: Institute for Diagnostic and Interventional Radiology, Clinics for Neuroradiology and Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.
authors.forename: V A
authors.initials: VA
authors.lastname: Runge
authors.affiliation: Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095, Jiefang Road, Wuhan City, Hubei Province 430030, China. Electronic address: lilyboston2002@163.com.
authors.forename: X
authors.initials: X
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D058566:Sacroiliitis / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013167:Spondylitis, Ankylosing / Q000175:diagnosis*; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D002097:C-Reactive Protein