title: Unciflavones A-F, six novel flavonoids from Selaginella uncinata (Desv.) Spring.
abstract: Six new flavonoids, unciflavones A-F (1-6), have been isolated from medicinal plant Selaginella uncinata (Desv.) Spring. Their structures were established on the basis of extensive NMR analysis including 1D NMR ((1)H, (13)C and DEPT) and 2D NMR (COSY, HSQC, HMBC) experiments as well as HRESIMS analysis. All compounds possess exceptional structural features with an aryl substituent at the C-8 position, which are uncommonly encountered in natural resources and firstly reported in genus Selaginella.
authors.affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China; Department of Pharmaceutical Science, Medical College of Hunan Normal University, Changsha, Hunan 410013, PR China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zou
authors.affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.
authors.forename: Kang-Ping
authors.initials: KP
authors.lastname: Xu
authors.affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.
authors.forename: Fu-Shuang
authors.initials: FS
authors.lastname: Li
authors.affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.
authors.forename: Zhen-Xing
authors.initials: ZX
authors.lastname: Zou
authors.affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.
authors.forename: Rui
authors.initials: R
authors.lastname: Liu
authors.affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.
authors.forename: Rui-Huan
authors.initials: RH
authors.lastname: Liu
authors.affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China.
authors.forename: Lei-Hong
authors.initials: LH
authors.lastname: Tan
authors.affiliation: School of Pharmaceutical Sciences, Central South University, Changsha 410013, PR China; Xiangya Hospital of Central South University, Changsha 410008, PR China. Electronic address: tgs395@csu.edu.cn.
authors.forename: Gui-Shan
authors.initials: GS
authors.lastname: Tan
mesh_terms: D045744:Cell Line, Tumor; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D032503:Selaginellaceae / Q000737:chemistry*
chemical_list: D005419:Flavonoids
keywords: 8-Aryl flavonoids; Cytotoxicity; Selaginella; Selaginella uncinata; Unciflavones A–F