title: Endoscopic treatment of postoperative benign bile duct stricture compared with malignant bile duct stricture.
abstract: OBJECTIVE
  Endoscopic treatment for postoperative benign bile duct stricture (BBS) is a therapeutic challenge. No previous studies have compared endoscopic treatments for BBS and malignant bile duct stricture (MBS). The aim of this study was to compare endoscopic treatments for postoperative BBS and MBS.
  
  
  METHODS
  This study enrolled 22 consecutive patients with a diagnosis of postoperative BBS and 110 patients diagnosed with MBS. Cases involving digestive tract reconstruction were excluded. We compared the length of the bile duct strictures, the success rate of endoscopic treatment, and the incidence of complications.
  
  
  RESULTS
  The following results were obtained for the postoperative BBS and MBS groups, respectively: length of bile duct stricture, 6.50 mm vs. 24.3 mm (P<0.0001); success rate of endoscopic treatment, 90.9% vs. 93.6% (P=0.6551). Post-ERCP pancreatitis occurred after 11 sessions (10.7%) vs. 7 sessions (1.83%) (P=0.0002), and post-ERCP cholangitis occurred after 7 sessions (6.80%) vs. 4 sessions (1.04%) (P=0.0021). BBS was a significant risk factor for post-ERCP pancreatitis and cholangitis based on a multivariate analysis (OR, 10.732; P=0.0022; OR, 6.443; P=0.0260).
  
  
  CONCLUSIONS
  Post-ERCP-related complications were more frequent after postoperative BBS than after MBS. The need for careful endoscopic treatment may be greater for postoperative BBS cases than for MBS cases.
authors.forename: Noritoshi
authors.initials: N
authors.lastname: Kobayashi
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Sato
authors.forename: Shingo
authors.initials: S
authors.lastname: Kato
authors.forename: Seitaro
authors.initials: S
authors.lastname: Watanabe
authors.forename: Kunihiro
authors.initials: K
authors.lastname: Hosono
authors.forename: Kensuke
authors.initials: K
authors.lastname: Kubota
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Takedaz
authors.forename: Itaru
authors.initials: I
authors.lastname: Endo
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nakajima
authors.forename: Shin
authors.initials: S
authors.lastname: Maeda
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Ichikawa
mesh_terms: D000293:Adolescent; D000368:Aged; D001662:Biliary Tract Surgical Procedures / Q000009:adverse effects*; D016009:Chi-Square Distribution; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects / Q000295:instrumentation; D002779:Cholestasis / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009369:Neoplasms / Q000150:complications*; D016017:Odds Ratio; D010195:Pancreatitis / Q000209:etiology; D012307:Risk Factors; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome