title: Characteristics of patients with spontaneous splenic rupture.
abstract: In the present study, we aim to share our clinical experience in patients with spontaneous splenic rupture. Splenic rupture without trauma is known as spontaneous splenic rupture. The major problems in the management of spontaneous splenic rupture are missed or delayed diagnosis due to the lack of trauma in most cases. The records of all patients, who were admitted to Cerrahpaşa Medical Faculty, Istanbul University, were retrospectively reviewed from January 2000 to March 2013. Twelve patients were admitted to the emergency department and they were diagnosed with spontaneous splenic rupture. The mean age was 47.6 years. All patients had complaints of abdominal pain. The mean hematocrit value was 22%. Radiologic assessment revealed hemoperitoneum and/or subcapsular hematoma in 8 patients while splenic abscess was diagnosed in 2 patients. Eleven patients underwent splenectomy whereas one was managed conservatively. The most common cause of spontaneous splenic rupture was determined to be use of anticoagulants. Etiology was considered to be idiopathic in 1 patient. Two patients died in the postoperative period. Although rare, spontaneous splenic rupture must be suspected in emergency patients who have used especially anticoagulants and antiaggregants and who have had no recent history of trauma. One of the important causes of mortality is missed or delayed diagnosis.
authors.affiliation: 1 Department of General Surgery, Istanbul University, Istanbul, Turkey.
authors.forename: Pinar Cigdem
authors.initials: PC
authors.lastname: Kocael
authors.forename: Osman
authors.initials: O
authors.lastname: Simsek
authors.forename: Ismail Ahmet
authors.initials: IA
authors.lastname: Bilgin
authors.forename: Onur
authors.initials: O
authors.lastname: Tutar
authors.forename: Kaya
authors.initials: K
authors.lastname: Saribeyoglu
authors.forename: Salih
authors.initials: S
authors.lastname: Pekmezci
authors.forename: Ertugrul
authors.initials: E
authors.lastname: Goksoy
mesh_terms: D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012422:Rupture, Spontaneous; D013156:Splenectomy; D013161:Splenic Rupture / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D014421:Turkey / Q000453:epidemiology
chemical_list: D000925:Anticoagulants
keywords: Atraumatic; Drug use; Mortality; Splenic rupture; Spontaneous