title: Spatial localisation of curcumin and rapid screening of the chemical compositions of turmeric rhizomes (Curcuma longa Linn.) using Direct Analysis in Real Time-Mass Spectrometry (DART-MS).
abstract: Curcumin is a potent antioxidant agent having versatile biological activities is present in turmeric rhizomes (Curcuma longa Linn.). Powder of turmeric rhizomes is consumes as curry spicy worldwide, especially in Asia. In this study, we demonstrate that, bioactive curcumin and its analog demethoxycurcumin are chiefly concentrated in the pith rather than the other parts of the turmeric rhizomes and it was discovered using modern atmospheric ionisation source 'Direct Analysis in Real Time' (DART) connected with an Ion Trap Mass Spectrometry. In addition, all the major components present in turmeric rhizomes were detected in positive and/or in negative ion mode using DART.
authors.affiliation: Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address: afmrahman@ksu.edu.sa.
authors.forename: A F M Motiur
authors.initials: AF
authors.lastname: Rahman
authors.affiliation: Department of Chemistry, Faculty of Science, King Abdul Aziz University, Jeddah 21589, Saudi Arabia.
authors.forename: Rihab F
authors.initials: RF
authors.lastname: Angawi
authors.affiliation: Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.
authors.forename: Adnan A
authors.initials: AA
authors.lastname: Kadi
mesh_terms: D001208:Asia; D030024:Curcuma / Q000737:chemistry*; D003474:Curcumin / Q000031:analogs & derivatives / Q000032:analysis*; D036381:Diarylheptanoids; D013058:Mass Spectrometry / Q000379:methods*; D027343:Rhizome / Q000737:chemistry
chemical_list: D036381:Diarylheptanoids; D003474:Curcumin; C050229:demethoxycurcumin
keywords: Curcuma longa Linn.; Curcumin; DART; Turmeric