title: Advancing technologies for the diagnosis and management of infections.
abstract: Infections remain a significant problem among surgical patients. Technological advances, especially in the arena of nano-technology, have markedly improved the ability to detect, prevent and treat surgical infections. No longer limited to culture-based methods of pathogen detection or standard antimicrobial therapies, options for management of surgical infections are rapidly expanding. Such advances are critical in this era of rapidly developing resistant and virulent strains of organisms. Further, our understanding of the host pathogen interaction grows exponentially with the development of computer-based modeling, aiding in expediting research endeavors.
authors.affiliation: Division of Trauma and Surgical Critical Care, Department of Surgery, Alpert Medical School Brown University, Rhode Island Hospital, 435 APC Building, 593 Eddy Street, Providence, RI 02903, USA. Electronic address: Dheffernan@Brown.edu.
authors.forename: Daithi S
authors.initials: DS
authors.lastname: Heffernan
authors.affiliation: Department of Surgery, Alpert Medical School Brown University, Rhode Island Hospital, 429 APC Building, 593 Eddy Street, Providence, RI 02903, USA.
authors.forename: Elizabeth D
authors.initials: ED
authors.lastname: Fox
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001435:Bacteriophages; D055499:Catheter-Related Infections / Q000517:prevention & control; D004269:DNA, Bacterial / Q000032:analysis; D006801:Humans; D017053:Infection Control / Q000379:methods; D046210:Microfluidic Analytical Techniques; D008954:Models, Biological; D020411:Oligonucleotide Array Sequence Analysis; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013530:Surgical Wound Infection / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial
keywords: Advancing technologies; Diagnosis; Infections; Management