title: Automated J wave detection from digital 12-lead electrocardiogram.
abstract: In this report we provide a method for automated detection of J wave, defined as a notch or slur in the descending slope of the terminal positive wave of the QRS complex, using signal processing and functional data analysis techniques. Two different sets of ECG tracings were selected from the EPICARE ECG core laboratory, Wake Forest School of Medicine, Winston Salem, NC. The first set was a training set comprised of 100 ECGs of which 50 ECGs had J-wave and the other 50 did not. The second set was a test set (n=116 ECGs) in which the J-wave status (present/absent) was only known by the ECG Center staff. All ECGs were recorded using GE MAC 1200 (GE Marquette, Milwaukee, Wisconsin) at 10mm/mV calibration, speed of 25mm/s and 500HZ sampling rate. All ECGs were initially inspected visually for technical errors and inadequate quality, and then automatically processed with the GE Marquette 12-SL program 2001 version (GE Marquette, Milwaukee, WI). We excluded ECG tracings with major abnormalities or rhythm disorder. Confirmation of the presence or absence of a J wave was done visually by the ECG Center staff and verified once again by three of the coauthors. There was no disagreement in the identification of the J wave state. The signal processing and functional data analysis techniques applied to the ECGs were conducted at Duke University and the University of Toronto. In the training set, the automated detection had sensitivity of 100% and specificity of 94%. For the test set, sensitivity was 89% and specificity was 86%. In conclusion, test results of the automated method we developed show a good J wave detection accuracy, suggesting possible utility of this approach for defining and detection of other complex ECG waveforms.
authors.affiliation: Department of Mathematics and Information Initiative (iiD), Duke University, Durham, NC.
authors.forename: Yi Grace
authors.initials: YG
authors.lastname: Wang
authors.affiliation: Department of Mathematics, University of Toronto, Toronto, ON. Electronic address: hauwu@math.toronto.edu.
authors.forename: Hau-Tieng
authors.initials: HT
authors.lastname: Wu
authors.affiliation: Department of Mathematics and Information Initiative (iiD), Duke University, Durham, NC.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Daubechies
authors.affiliation: Epidemiological Cardiology Research Center (EPICARE), Department of Epidemiology and Prevention, and Department of Medicine-Cardiology, Wake Forest School of Medicine, Winston-Salem, NC.
authors.forename: Yabing
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Community and Family Medicine, Duke University Medical Center, Durham, NC.
authors.forename: E Harvey
authors.initials: EH
authors.lastname: Estes
authors.affiliation: Epidemiological Cardiology Research Center (EPICARE), Department of Epidemiology and Prevention, and Department of Medicine-Cardiology, Wake Forest School of Medicine, Winston-Salem, NC. Electronic address: esoliman@wakehealth.edu.
authors.forename: Elsayed Z
authors.initials: EZ
authors.lastname: Soliman
mesh_terms: D000465:Algorithms; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004562:Electrocardiography / Q000379:methods*; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted
keywords: Automated J wave detection; Functional data analysis; Signal processing