title: The management of abnormal haemostasis in the ICU.
abstract: The aetiology and management of haemostatic abnormalities in critical care patients are considered in this narrative review. The mechanisms of normal haemostasis and derangements that occur as a result of sepsis and organ dysfunction are discussed. Finally, the management of haemostatic abnormalities as they relate to critical care practice are considered, including the management of heparin-induced thrombocytopenia.
authors.affiliation: Department of Intensive Care, Guys and St. Thomas' NHS Foundation Trust, London, UK.
authors.forename: A
authors.initials: A
authors.lastname: Retter
authors.forename: N A
authors.initials: NA
authors.lastname: Barrett
mesh_terms: D001778:Blood Coagulation Disorders / Q000209:etiology / Q000628:therapy*; D005340:Fibrinogen / Q000627:therapeutic use; D006487:Hemostasis; D006493:Heparin / Q000009:adverse effects; D006801:Humans; D007362:Intensive Care Units; D010949:Plasma; D013921:Thrombocytopenia / Q000628:therapy
chemical_list: D005340:Fibrinogen; D006493:Heparin