title: Antidiabetic medications and polypharmacy.
abstract: Polypharmacy, or the use of multiple medications, is a serious concern for providers who care for older adults, as polypharmacy is associated with medication nonadherence, drug-drug interactions, drug-disease interactions, and adverse drug events. Multiple medications, high chronic disease burden, and age-related physiologic changes make management of older adults with diabetes increasingly difficult. Given high medication burden and potential for increased medication sensitivity in this patient population, it is prudent that providers are aware of potential risks and benefits of antidiabetic medications and implement shared decision-making practices to ensure appropriate care for older adults with diabetes.
authors.affiliation: Geriatric Pharmacotherapy Program, Department of Pharmacotherapy & Outcomes Science, Virginia Commonwealth University, Smith Building, Room 338, 410 North 12th Street, PO Box 980533, Richmond, VA 23298-0533, USA. Electronic address: epperon@vcu.edu.
authors.forename: Emily P
authors.initials: EP
authors.lastname: Peron
authors.affiliation: Geriatric Pharmacotherapy Program, Department of Pharmacotherapy & Outcomes Science, Virginia Commonwealth University, Smith Building, Room 336, 410 North 12th Street, PO Box 980533, Richmond, VA 23298-0533, USA.
authors.forename: Kelechi C
authors.initials: KC
authors.lastname: Ogbonna
authors.affiliation: Geriatric Pharmacotherapy Program, Department of Pharmacotherapy & Outcomes Science, Virginia Commonwealth University, Smith Building, Room 220B, 410 North 12th Street, PO Box 980533, Richmond, VA 23298-0533, USA.
authors.forename: Krista L
authors.initials: KL
authors.lastname: Donohoe
mesh_terms: D000367:Age Factors; D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D019338:Polypharmacy; D012307:Risk Factors
chemical_list: D007004:Hypoglycemic Agents
keywords: Adverse drug events; Diabetic complications; Geriatric syndromes; Hypoglycemic agents; Polypharmacy