title: Intraoperative monitoring for intracranial aneurysms: the Michigan experience.
abstract: Intraoperative neurophysiological monitoring is routinely used during the repair (endovascular or microsurgical) of intracranial aneurysms at major centers. There is a continued need of data sets from institutions with dedicated intraoperative neurophysiological monitoring services to further define the predictive factors of postoperative neurological deficits. We retrospectively reviewed and analyzed our database of all patients who underwent repair of intracranial aneurysms (endovascular or microsurgical). A total of 406 patients underwent 470 procedures. The changes were noted during monitoring in 3.83% of the cases. Most of the changes were first detected in somatosensory evoked potential (88.89%) followed by brainstem auditory evoked potential (16.67%). Changes were completely reversible in 44.44%, only partly reversible in 22.22%, and irreversible in 33.33% of cases. Intraoperative neurophysiological monitoring changes demonstrated high sensitivity, specificity, and negative predictive value for postoperative neurological deficits. The association between intraoperative neurophysiological monitoring changes and Glasgow outcome scale was significant for reversible changes compared against irreversible and partly reversible changes. Presence of any intraoperative neurophysiological monitoring modality change during repair of intracranial aneurysm may suggest a higher risk for postoperative neurological deficits. Reversibility of the changes is a favorable marker, whereas irreversible changes are predictive of postoperative neurological deficits with deterioration of Glasgow outcome scale on a longer follow-up.
authors.affiliation: *Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, U.S.A.; and Departments of †Neurosurgery; and ‡Neurology, University of Michigan, Ann Arbor, Michigan, U.S.A.
authors.forename: Kinshuk
authors.initials: K
authors.lastname: Sahaya
authors.forename: Aditya S
authors.initials: AS
authors.lastname: Pandey
authors.forename: Byron G
authors.initials: BG
authors.lastname: Thompson
authors.forename: Brian R
authors.initials: BR
authors.lastname: Bush
authors.forename: Daniela N
authors.initials: DN
authors.lastname: Minecan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D004569:Electroencephalography; D004576:Electromyography; D057510:Endovascular Procedures / Q000009:adverse effects; D016057:Evoked Potentials, Auditory, Brain Stem; D005073:Evoked Potentials, Somatosensory; D005260:Female; D023261:Glasgow Outcome Scale; D006801:Humans; D007223:Infant; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D064795:Intraoperative Neurophysiological Monitoring / Q000379:methods*; D008297:Male; D008824:Michigan; D008866:Microsurgery / Q000009:adverse effects; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology; D011237:Predictive Value of Tests; D020127:Recovery of Function; D012189:Retrospective Studies; D065908:Transcranial Direct Current Stimulation; D016896:Treatment Outcome; D055815:Young Adult