title: On-line double isotope dilution laser ablation inductively coupled plasma mass spectrometry for the quantitative analysis of solid materials.
abstract: We report on the determination of trace elements in solid samples by the combination of on-line double isotope dilution and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). The proposed method requires the sequential analysis of the sample and a certified natural abundance standard by on-line IDMS using the same isotopically-enriched spike solution. In this way, the mass fraction of the analyte in the sample can be directly referred to the certified standard so the previous characterization of the spike solution is not required. To validate the procedure, Sr, Rb and Pb were determined in certified reference materials with different matrices, including silicate glasses (SRM 610, 612 and 614) and powdered samples (PACS-2, SRM 2710a, SRM 1944, SRM 2702 and SRM 2780). The analysis of powdered samples was carried out both by the preparation of pressed pellets and by lithium borate fusion. Experimental results for the analysis of powdered samples were in agreement with the certified values for all materials. Relative standard deviations in the range of 6-21% for pressed pellets and 3-21% for fused solids were obtained from n=3 independent measurements. Minimal sample preparation, data treatment and consumption of the isotopically-enriched isotopes are the main advantages of the method over previously reported approaches.
authors.affiliation: Department of Physical and Analytical Chemistry, Faculty of Chemistry, University of Oviedo, Julian Clavería, 8, Oviedo 33006, Spain. Electronic address: fernandezbeatriz@uniovi.es.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Fernández
authors.affiliation: Department of Physical and Analytical Chemistry, Faculty of Chemistry, University of Oviedo, Julian Clavería, 8, Oviedo 33006, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Rodríguez-González
authors.affiliation: Department of Physical and Analytical Chemistry, Faculty of Chemistry, University of Oviedo, Julian Clavería, 8, Oviedo 33006, Spain.
authors.forename: J Ignacio
authors.initials: JI
authors.lastname: García Alonso
authors.affiliation: Chemical Sciences Division, Material Measurement Laboratory, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8391, Gaithersburg, MA 20899, USA.
authors.forename: Julien
authors.initials: J
authors.lastname: Malherbe
authors.affiliation: ISC Science-Innovative Solutions in Chemistry, Oviedo, Spain.
authors.forename: Sergio
authors.initials: S
authors.lastname: García-Fonseca
authors.affiliation: Department of Physical and Analytical Chemistry, Faculty of Chemistry, University of Oviedo, Julian Clavería, 8, Oviedo 33006, Spain.
authors.forename: Rosario
authors.initials: R
authors.lastname: Pereiro
authors.affiliation: Department of Physical and Analytical Chemistry, Faculty of Chemistry, University of Oviedo, Julian Clavería, 8, Oviedo 33006, Spain.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Sanz-Medel
mesh_terms: D001881:Borates / Q000737:chemistry; D005898:Glass / Q000737:chemistry; D007554:Isotopes / Q000737:chemistry; D007834:Lasers; D018020:Lithium Compounds / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods*; D058626:Plasma Gases / Q000737:chemistry*; D014131:Trace Elements / Q000032:analysis* / Q000737:chemistry
chemical_list: D001881:Borates; D007554:Isotopes; D018020:Lithium Compounds; D058626:Plasma Gases; D014131:Trace Elements; C021051:lithium borate
keywords: Isotope dilution mass spectrometry; Laser ablation inductively coupled plasma mass spectrometry; Powdered samples; Quantification methodology