title: Cadmium, lead and mercury concentrations and their influence on morphological parameters in blood donors from different age groups from southern Poland.
abstract: Due to industrial development, environmental contamination with metals increases which leads to higher human exposure via air, water and food. In order to evaluate the level of the present exposition, the concentrations of metals can be measured in such biological materials as human blood. In this study, we assessed the concentrations of cadmium (Cd), mercury (Hg) and lead (Pb) in blood samples from male blood donors from southern Poland (Europe) born in 1994 (n=30) and between 1947 and 1955 (n=30). Higher levels of Pb were seen in the group of older men (4.48 vs 2.48μg/L), whereas the Hg levels were lower (1.78 vs 4.28μg/L). Cd concentrations did not differ between age groups (0.56μg/L). The levels of Cd and Pb in older donors were significantly correlated (Spearman R 0.5135). We also observed a positive correlation between the number of red blood cells (RBC) and Hg concentrations in the older group (Spearman R 0.4271). Additionally, we noted numerous correlations among morphological parameters. Based on our results, we can state that metals influence the blood morphology and their concentrations in blood vary among age groups.
authors.affiliation: Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland. Electronic address: moniajanicka@gmail.com.
authors.forename: Monika
authors.initials: M
authors.lastname: Janicka
authors.affiliation: Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland. Electronic address: ljbinkowski@gmail.com.
authors.forename: Łukasz J
authors.initials: ŁJ
authors.lastname: Binkowski
authors.affiliation: Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland. Electronic address: martynablaszczyk88@tlen.pl.
authors.forename: Martyna
authors.initials: M
authors.lastname: Błaszczyk
authors.affiliation: Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland. Electronic address: joannapaluch88@gmail.com.
authors.forename: Joanna
authors.initials: J
authors.lastname: Paluch
authors.affiliation: Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland. Electronic address: szymek@ap.krakow.pl.
authors.forename: Włodzimierz
authors.initials: W
authors.lastname: Wojtaś
authors.affiliation: Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland. Electronic address: peter.massanyi@uniag.sk.
authors.forename: Peter
authors.initials: P
authors.lastname: Massanyi
authors.affiliation: Institute of Biology, Pedagogical University of Cracow, Podbrzezie 3, 31-054 Cracow, Poland. Electronic address: rms@up.krakow.pl.
authors.forename: Robert
authors.initials: R
authors.lastname: Stawarz
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D001773:Blood Cells / Q000166:cytology*; D001782:Blood Donors; D002104:Cadmium / Q000097:blood*; D006801:Humans; D007854:Lead / Q000097:blood*; D057230:Limit of Detection; D008297:Male; D008628:Mercury / Q000097:blood*; D011044:Poland; D018709:Statistics, Nonparametric; D055815:Young Adult
chemical_list: D002104:Cadmium; D007854:Lead; D008628:Mercury
keywords: Blood morphology; Cadmium; Lead; Mercury; Metal influence