title: The relationship between body composition and femoral neck osteoporosis or osteopenia in adults with previous poliomyelitis.
abstract: BACKGROUND
  Articles in the literature describing the association between body composition and osteoporosis in subjects with poliomyelitis are scarce.
  
  
  OBJECTIVE
  To assess the relationship between body composition and femoral neck osteoporosis or osteopenia in adults with previous polio.
  
  
  METHODS
  After excluding postmenopausal women, 44 polio (mean age ± standard deviation, 46.1 ± 3.3 years) and 44 able-bodied control volunteers (47.0 ± 4.0 years) participated in the study. Each participant's femoral neck bone mineral density (FNBMD) and whole body composition were measured using dual-energy X-ray absorptiometry. With local reference BMD values of normal young adults installed in the instrument, we obtained T-score values that depended on each FNBMD value. A T-score value of ≤-1.0 indicated decreased T-score, including osteoporosis (T-score ≤ -2.5) and osteopenia (-1.0 to -2.5). This study conducted logistic regression analyses to find factors associated with osteoporosis and osteopenia.
  
  
  RESULTS
  Based on the FNBMD T-score values, 60.0% of middle-aged men with polio had osteoporosis. In adjusted logistic regression analyses, total lean tissue mass (Adjusted odds ratio [95% confidence interval], 0.74 [0.56-0.99], P < 0.05) and male gender (947.16 [6.02-148,926.16], P < 0.01) were important factors associated with decreased T-score in polio group.
  
  
  CONCLUSIONS
  Osteoporosis or osteopenia is a common medical problem for middle-aged men with polio. Reduced total lean tissue mass seems to be one of the important factors associated with osteoporosis or osteopenia among subjects with polio. Further research for a clinical tool to assess lean tissue mass for subjects with polio is needed.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Graduate Institute of Injury Prevention and Control, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan.
authors.forename: Kwang-Hwa
authors.initials: KH
authors.lastname: Chang
authors.affiliation: Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan.
authors.forename: Sung-Hui
authors.initials: SH
authors.lastname: Tseng
authors.affiliation: Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, Tainan, Taiwan.
authors.forename: Yu-Ching
authors.initials: YC
authors.lastname: Lin
authors.affiliation: Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan; Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
authors.forename: Chien-Hung
authors.initials: CH
authors.lastname: Lai
authors.affiliation: Department of Diagnostic Radiology, Taipei Medical University Hospital, Taipei, Taiwan.
authors.forename: Wen-Tien
authors.initials: WT
authors.lastname: Hsiao
authors.affiliation: Department of Physical Medicine and Rehabilitation, Taipei Medical University Hospital, Taipei, Taiwan; Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address: csc@tmu.edu.tw.
authors.forename: Shih-Ching
authors.initials: SC
authors.lastname: Chen
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D001823:Body Composition; D001825:Body Fluid Compartments / Q000378:metabolism*; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000209:etiology / Q000378:metabolism; D016022:Case-Control Studies; D006233:Persons with Disabilities; D005260:Female; D005272:Femur Neck / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009132:Muscles; D016017:Odds Ratio; D010024:Osteoporosis / Q000453:epidemiology / Q000209:etiology* / Q000378:metabolism; D011051:Poliomyelitis / Q000150:complications*; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors
keywords: Body composition; Femoral neck; Osteoporosis; Poliomyelitis