title: Beneficial effect of low caloric intake in the early period after orthotopic liver transplantation: a new concept using graft weight.
abstract: OBJECTIVE
  Although various factors are correlated with early graft function after orthotopic liver transplantation (OLT), caloric supplementation is not considered in postoperative period. This retrospective study investigated the correlation between caloric intake and early graft function and compared calorie/ body weight ratio (CBWR) and calorie/graft weight ratio (CGWR) as standards for nutritional provision.
  
  
  METHODS
  Patients were divided into the low caloric group (<18 kcal/kg/day) and eucaloric group (≥18 kcal/kg/day) according to caloric intake until 48 hours post-OLT. Graft function was assessed according to aminotransferase level, bilirubin level, and international normalised ratio (INR) on postoperative days (POD) 0, 2, and 7. The variables associated with caloric intake were compared to identify the superiority between CBWR and CGWR.
  
  
  RESULTS
  There were 32 and 8 patients in the low caloric and eucaloric groups. INR on POD 2 was significantly lower in the low caloric group (p = 0.018). CGWR was more strongly correlated with INR than CBWR on POD 2 (r = 0.08, p = 0.63 vs. r = 0.36, p = 0.024).
  
  
  CONCLUSIONS
  Low caloric intake has a beneficial effect on the restoration of early graft function. CGWR is superior to CBWR as a standard for nutritional supplementation.
authors.forename: Kyu-Hyouck
authors.initials: KH
authors.lastname: Kyoung
authors.forename: Sung-Gyu
authors.initials: SG
authors.lastname: Lee
authors.forename: Chang Woo
authors.initials: CW
authors.lastname: Nam
authors.forename: Yang Won
authors.initials: YW
authors.lastname: Nah
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001835:Body Weight; D031204:Caloric Restriction; D002149:Energy Intake; D005260:Female; D006801:Humans; D019934:International Normalized Ratio; D008111:Liver Function Tests; D016031:Liver Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D009752:Nutritional Status; D009929:Organ Size; D011183:Postoperative Complications / Q000097:blood / Q000503:physiopathology / Q000517:prevention & control*; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D001663:Bilirubin