title: Design and implementation of a study evaluating extinction processes to food cues in obese children: the Intervention for Regulations of Cues Trial (iROC).
abstract: Obesity and its health sequelae affect a significant portion of children in the United States. Yet, the current gold-standard family-based behavioral weight-loss treatments are only effective for one-third of children long-term. Therefore, we developed iROC (Intervention for Regulation of Cues) to specifically target a method to decrease overeating in overweight children, based on learning theory, to inform and enhance interventions targeting diet and obesity in youth. This study will rigorously test extinction processes as a method of decreasing physiological and psychological responses to food cues in overweight and obese children. Through exposing children to their highly craved foods, and 'training the brain and body' to decrease overeating, we are hoping to produce longer-lasting weight loss or weight-gain prevention over time.
authors.affiliation: University of California San Diego, Department of Pediatrics, United States; University of California San Diego, Department of Psychiatry, United States. Electronic address: kboutelle@ucsd.edu.
authors.forename: Kerri N
authors.initials: KN
authors.lastname: Boutelle
authors.affiliation: University of California San Diego, Department of Pediatrics, United States.
authors.forename: June
authors.initials: J
authors.lastname: Liang
authors.affiliation: University of California San Diego, Department of Pediatrics, United States.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Knatz
authors.affiliation: University of California San Diego, Department of Pediatrics, United States.
authors.forename: Brittany
authors.initials: B
authors.lastname: Matheson
authors.affiliation: University of California San Diego, Department of Psychiatry, United States.
authors.forename: Victoria
authors.initials: V
authors.lastname: Risbrough
authors.affiliation: University of California San Diego, Department of Family and Preventative Medicine, United States.
authors.forename: David
authors.initials: D
authors.lastname: Strong
authors.affiliation: University of California San Diego, Department of Pediatrics, United States.
authors.forename: Kyung E
authors.initials: KE
authors.lastname: Rhee
authors.affiliation: University of California, Los Angeles, Department of Psychology, United States.
authors.forename: Michelle G
authors.initials: MG
authors.lastname: Craske
authors.affiliation: Duke University, Department of Psychiatry, United States.
authors.forename: Nancy
authors.initials: N
authors.lastname: Zucker
authors.affiliation: University of Vermont, Department of Psychology, United States.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Bouton
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001521:Behavior Therapy / Q000379:methods*; D015992:Body Mass Index; D002648:Child; D003463:Cues; D002149:Energy Intake; D005247:Feeding Behavior / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D063766:Pediatric Obesity / Q000523:psychology / Q000628:therapy*; D012107:Research Design; D012737:Sex Factors; D012959:Socioeconomic Factors; D015431:Weight Loss
keywords: Child; Cue exposure; Eating in the absence of hunger; Obesity; Overeating