title: Amyloid-like fibrils labeled with magnetic nanoparticles.
abstract: A number of human diseases are associated with the formation of insoluble protein aggregates commonly known as amyloid fibrils or amyloid plaques. Similar materials can be prepared in vitro resulting in so-called amyloid-like fibrils. Herein is discussed how to prepare such fibrils labeled with magnetic nanoparticles. Such materials have the potential to be used as magnetic probes for magnetic resonance imaging applications.
authors.forename: Niclas
authors.initials: N
authors.lastname: Solin
mesh_terms: D000682:Amyloid / Q000737:chemistry* / Q000378:metabolism*; D000818:Animals; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007501:Iron / Q000737:chemistry; D008279:Magnetic Resonance Imaging; D058185:Magnetite Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D012995:Solubility; D013194:Staining and Labeling
chemical_list: D000682:Amyloid; D058185:Magnetite Nanoparticles; D007501:Iron