title: Intensity-modulated radiotherapy for lung cancer: current status and future developments.
abstract: Radiotherapy plays an important role in the management of lung cancer, with over 50% of patients receiving this modality at some point during their treatment. Intensity-modulated radiotherapy (IMRT) is a technique that adds fluence modulation to beam shaping, which improves radiotherapy dose conformity around the tumor and spares surrounding normal structures. Treatment with IMRT is becoming more widely available for the treatment of lung cancer, despite the paucity of high level evidence supporting the routine use of this more resource intense and complex technique. In this review article, we have summarized data from planning and clinical studies, discussed challenges in implementing IMRT, and made recommendations on the minimum requirements for safe delivery of IMRT.
authors.affiliation: *Radiotherapy Related Research, The Christie NHS Foundation Trust and University of Manchester, Manchester, United Kingdom; †Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, United Kingdom; and ‡Department of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.
authors.forename: Clara
authors.initials: C
authors.lastname: Chan
authors.forename: Stephanie
authors.initials: S
authors.lastname: Lang
authors.forename: Carl
authors.initials: C
authors.lastname: Rowbottom
authors.forename: Matthias
authors.initials: M
authors.lastname: Guckenberger
authors.forename: Corinne
authors.initials: C
authors.lastname: Faivre-Finn
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000532:radiotherapy*; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy*; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods / Q000639:trends