title: Short-term and mid-term outcome of total ankle replacement in haemophilic patients.
abstract: BACKGROUND
  Ankle arthropathy is very frequent in haemophilic patients. Prostheses are valuable alternatives to arthrodesis in non-haemophilic patients. We report the experience of a single centre in France on the use of prostheses in haemophilic patients.
  
  
  METHODS
  Retrospective study of 21 patients with haemarthropathy who underwent ankle arthroplasty (32 ankles), with additional surgery, if needed, from July 2002 to September 2009 (mean follow-up 4.4±1.7 years). The American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot scale was used to evaluate pain, function, ankle mobility and alignment.
  
  
  RESULTS
  The overall AOFAS score improved from 40.2±19.4 (pre-surgery) to 85.3±11.4 (post-surgery). The function score increased from 23.6±7.7 to 35.9±6.7 and dorsiflexion from 0.3°±5.0° to 10.3°±4.4°. Two patients underwent further ankle arthrodesis. On X-ray, both tibial and talar components were stable and correctly placed in all ankles. Alignment was good.
  
  
  CONCLUSIONS
  Ankle arthroplasty is a promising alternative to arthrodesis in haemophilic patients.
authors.affiliation: Hôpital Privé les Franciscaines, Nîmes, France. Electronic address: c.asencio@wanadoo.fr.
authors.forename: J G
authors.initials: JG
authors.lastname: Asencio
authors.affiliation: Hôpital Privé les Franciscaines, Nîmes, France.
authors.forename: C
authors.initials: C
authors.lastname: Leonardi
authors.affiliation: Centre Régional du Traitement de l'Hémophilie, CHU Montpellier, France.
authors.forename: C
authors.initials: C
authors.lastname: Biron-Andreani
authors.affiliation: Centre Régional du Traitement de l'Hémophilie, CHU Montpellier, France.
authors.forename: J F
authors.initials: JF
authors.lastname: Schved
mesh_terms: D000328:Adult; D000368:Aged; D018771:Arthralgia / Q000601:surgery; D001174:Arthrodesis; D058737:Arthroplasty, Replacement, Ankle; D005169:Factor VIII / Q000627:therapeutic use; D005500:Follow-Up Studies; D006395:Hemarthrosis / Q000209:etiology / Q000601:surgery*; D006467:Hemophilia A / Q000150:complications*; D002836:Hemophilia B / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D010147:Pain Measurement; D026741:Physical Therapy Modalities; D011183:Postoperative Complications; D012086:Reoperation; D012189:Retrospective Studies; D055815:Young Adult; D014842:von Willebrand Diseases / Q000150:complications*
chemical_list: C078147:F8 protein, human; D005169:Factor VIII