title: Congenital peripheral primitive neuroectodermal tumor: a case treated successfully with multimodality treatment.
abstract: Neonatal tumors comprise less than two percent of childhood malignancies. Most are solid tumors, most common histologies being teratoma and neuroblastoma. We encountered a child who was detected to have a right arm mass on antenatal sonogram, which was diagnosed to be a primitive neuroectodermal tumor involving the triceps on fine needle aspiration cytology performed in the post-natal period. The child was successfully treated with multimodality treatment consisting of surgery, chemotherapy and radiotherapy. We also discuss briefly the problems associated with therapy in neonatal period. A review of all cases reported to have congenital Ewing's sarcoma family of tumors is presented. Novel therapies are needed to improve efficacy and decrease the devastating side effects of treatment in this age group.
authors.affiliation: Department of Radiotherapy, All India Institute of Medical Sciences, New Delhi 110029, India. Electronic address: drshikhagoyal@gmail.com.
authors.forename: Shikha
authors.initials: S
authors.lastname: Goyal
authors.affiliation: Department of Radiotherapy, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Ahitagni
authors.initials: A
authors.lastname: Biswas
authors.affiliation: Department of Pathology, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Ruchika
authors.initials: R
authors.lastname: Gupta
authors.affiliation: Department of Radiotherapy, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Bidhu Kalyan
authors.initials: BK
authors.lastname: Mohanti
mesh_terms: D001132:Arm / Q000473:pathology; D044963:Biopsy, Fine-Needle; D003131:Combined Modality Therapy / Q000379:methods*; D006801:Humans; D007223:Infant; D008297:Male; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000151:congenital* / Q000175:diagnosis* / Q000628:therapy*; D012512:Sarcoma, Ewing / Q000175:diagnosis; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal
keywords: Congenital tumor; Peripheral primitive neuroectodermal tumor; Radiation therapy