title: Surgical treatment of patients with unruptured intracranial aneurysms.
abstract: We present our experience with elective microsurgical clipping of unruptured intracranial aneurysms (UIA) and analyze this management. A total of 150 patients with UIA were reviewed and data were collected with regard to age, sex, presence of symptoms, location and size of the aneurysms, surgical complications and postoperative 1 year outcomes. Aneurysm size was assessed either by three-dimensional CT angiography or digital subtraction angiogram. Glasgow Outcome Scale was used to assess clinical outcomes. One hundred and fifty patients with 165 aneurysms were treated in this series. The mean size of the UIA was 5.6mm. Eighty aneurysms (48.5%) were less than 5mm in size, and 73 (44.2%) were from 5 to 10mm. Ten (6.1%) of the aneurysms were large and two (1.2%) were giant. One hundred and forty-three were asymptomatic and seven were symptomatic before surgery. The outcome was good in 147 patients (98%), and only three patients (2%) had a treatment-related unfavorable outcome. Five patients experienced transient neurological deficits and one patient experienced permanent neurological deficits. Overall 98.7% of the treated aneurysms were satisfactorily obliterated. Wound complications were seen only in three patients. In conclusion, UIA pose a significant challenge for neurosurgeons, where a delicate balance between benefits and possible risks must be weighed. If the requisite expertise is available, they can be treated surgically with low morbidity and a good outcome at specialized neurovascular centers.
authors.affiliation: Department of Neurosurgery, The First Affiliated Hospital of Xiamen University, Xiamen, China.
authors.forename: S F
authors.initials: SF
authors.lastname: Chen
authors.affiliation: Department of Neurosurgery, Fujita Health University Hospital, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470-1192, Japan. Electronic address: katoyoko@163.com.
authors.forename: Y
authors.initials: Y
authors.lastname: Kato
authors.affiliation: Department of Neurosurgery, St. Stephen's Hospital, Delhi, India.
authors.forename: R
authors.initials: R
authors.lastname: Sinha
authors.affiliation: Department of Neurosurgery, Nizam's Institute of Medical Science, Hyderabad, India.
authors.forename: A
authors.initials: A
authors.lastname: Kumar
authors.affiliation: Department of Neurosurgery, Fujita Health University Hospital, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470-1192, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Watabe
authors.affiliation: Department of Neurosurgery, Fujita Health University Hospital, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470-1192, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Imizu
authors.affiliation: Department of Neurosurgery, Fujita Health University Hospital, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470-1192, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Oda
authors.affiliation: Department of Neurosurgery, Fujita Health University Hospital, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470-1192, Japan.
authors.forename: D
authors.initials: D
authors.lastname: Oguri
authors.affiliation: Department of Neurosurgery, Fujita Health University Hospital, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470-1192, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Sano
authors.affiliation: Department of Neurosurgery, Fujita Health University Hospital, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi 470-1192, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Hirose
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000601:surgery*; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome
keywords: Clipping; Treatment; Unruptured intracranial aneurysm