title: Dietary fatty acid intakes and asthenozoospermia: a case-control study.
abstract: OBJECTIVE
  To investigate the association between dietary fatty acids intakes and asthenozoospermia.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  Infertility clinics.
  
  
  METHODS
  A total of 107 men with incident asthenozoospermia and 235 age-matched controls.
  
  
  METHODS
  None.
  
  
  METHODS
  Assessments of dietary intakes, semen quality, anthropometry, endocrine parameters, and demographic information.
  
  
  RESULTS
  According to the fully adjusted model, being in the highest tertile of total saturated fatty acids (odds ratio [OR] = 1.85, 95% confidence interval [CI] 1.24-2.96), total trans-fatty acids (OR = 2.53, 95% CI 1.54-3.92), palmitic acid (OR = 1.90, 95% CI 1.26-2.74), and stearic acid (OR = 2.13, 95% CI 1.29-3.88) was positively associated with asthenozoospermia. Whereas higher intakes of omega-3 polyunsaturated (OR = 0.68, 95% CI 0.58-0.94) and of docosahexaenoic (OR = 0.53, 95% CI 0.29-0.89) fatty acids were significantly associated with reduced odds of asthenozoospermia.
  
  
  CONCLUSIONS
  Our findings suggest that the high intake of saturated and trans-fats was positively related to the odds of having asthenozoospermia. Conversely, inverse and dose-dependent associations were found between asthenozoospermia and intake of omega-3 polyunsaturated fatty acids. The observed associations of different types of fatty acids underline the importance of the type of fat in the etiology of asthenozoospermia.
authors.affiliation: Students' Research Committee, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Ghazaleh
authors.initials: G
authors.lastname: Eslamian
authors.affiliation: Department of Andrology and Embryology, Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), Tehran, Iran.
authors.forename: Naser
authors.initials: N
authors.lastname: Amirjannati
authors.affiliation: Department of Community Nutrition, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Bahram
authors.initials: B
authors.lastname: Rashidkhani
authors.affiliation: Department of Andrology and Embryology, Reproductive Biotechnology Research Center, Avicenna Research Institute, Academic Center for Education, Culture and Research (ACECR), Tehran, Iran.
authors.forename: Mohammad-Reza
authors.initials: MR
authors.lastname: Sadeghi
authors.affiliation: Department of Biostatistics, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Ahmad-Reza
authors.initials: AR
authors.lastname: Baghestani
authors.affiliation: Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: a_hekmat2000@yahoo.com.
authors.forename: Azita
authors.initials: A
authors.lastname: Hekmatdoost
mesh_terms: D000328:Adult; D053627:Asthenozoospermia / Q000453:epidemiology* / Q000378:metabolism* / Q000473:pathology; D016022:Case-Control Studies; D004041:Dietary Fats / Q000378:metabolism*; D006801:Humans; D015994:Incidence; D007492:Iran / Q000453:epidemiology; D008297:Male; D012307:Risk Factors; D055101:Semen Analysis / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D004041:Dietary Fats
keywords: Dietary fatty acids; asthenozoospermia; male infertility; sperm motility