title: ¹⁸F-fluorodeoxyglucose PET/computed tomography for primary brain tumors.
abstract: Structural imaging with computed tomography (CT) and MR imaging is the mainstay in primary diagnosis of primary brain tumors, but these modalities depend on morphologic appearance and an intact blood-brain barrier, and important aspects of tumor biology are not addressed. Such issues may be alleviated by (18)F-fluorodeoxyglucose (FDG)-PET and FDG-PET/CT imaging, which may provide clinically important information with regard to primary differentiation between tumor types, initial staging and risk stratification, therapy planning, response evaluation, and recurrence detection. This article describes some of the potential contemporary applications of FDG and PET in primary brain tumors.
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, Søndre Boulevard 29, 5000 Odense, Denmark.
authors.forename: Eivind A
authors.initials: EA
authors.lastname: Segtnan
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, Søndre Boulevard 29, 5000 Odense, Denmark. Electronic address: soeren.hess@rsyd.dk.
authors.forename: Søren
authors.initials: S
authors.lastname: Hess
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, Søndre Boulevard 29, 5000 Odense, Denmark.
authors.forename: Peter
authors.initials: P
authors.lastname: Grupe
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, Søndre Boulevard 29, 5000 Odense, Denmark.
authors.forename: Poul Flemming
authors.initials: PF
authors.lastname: Høilund-Carlsen
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000628:therapy; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D064847:Multimodal Imaging / Q000295:instrumentation*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: (18)F-fluorodeoxyglucose; FDG; PET/CT; Primary brain tumor