title: Toxic potential of iron oxide, CdS/Ag₂S composite, CdS and Ag₂S NPs on a fresh water alga Mougeotia sp.
abstract: Nanoparticles (NPs) are being used in many industries ranging from medical, textile, automobile, consumer products, etc. This may increase the probability of their (NPs) release into the environment and fresh water ecosystems. The present study focuses on testing the potential effect of iron oxide, nanocomposite of cadmium sulfide and silver sulfide, cadmium sulfide and silver sulfide nanoparticles (NPs) on a fresh water alga Mougeotia sp. as the model organism. The alga was treated with different concentrations of NPs (0.1-25 mg/L). The NPs exposure caused lipid peroxidation and ROS production, and suppressed the antioxidant defense system such as catalase, glutathione reductase, and superoxide dismutase. Adsorption of NPs on algal surface and membrane damage were confirmed through microscopic evaluation and increase in protein content in extracellular medium. The present investigation pointed out the ecological implications of NPs. The study warrants the need for regulatory agencies to monitor and regulate the use of NPs.
authors.affiliation: Centre for Nanotechnology and Advanced Biomaterials, School of Chemical and Biotechnology, SASTRA University, Thanjavur 613401, Tamil Nadu, India.
authors.forename: E
authors.initials: E
authors.lastname: Jagadeesh
authors.affiliation: Centre for Nanotechnology and Advanced Biomaterials, School of Chemical and Biotechnology, SASTRA University, Thanjavur 613401, Tamil Nadu, India.
authors.forename: Behlol
authors.initials: B
authors.lastname: Khan
authors.affiliation: Centre for Nanotechnology and Advanced Biomaterials, School of Chemical and Biotechnology, SASTRA University, Thanjavur 613401, Tamil Nadu, India.
authors.forename: Preethy
authors.initials: P
authors.lastname: Chandran
authors.affiliation: Centre for Nanotechnology and Advanced Biomaterials, School of Chemical and Biotechnology, SASTRA University, Thanjavur 613401, Tamil Nadu, India. Electronic address: sudheerkhan@scbt.sastra.edu.
authors.forename: S Sudheer
authors.initials: SS
authors.lastname: Khan
mesh_terms: D000327:Adsorption; D020418:Algal Proteins / Q000037:antagonists & inhibitors* / Q000378:metabolism; D019187:Cadmium Compounds / Q000737:chemistry / Q000633:toxicity*; D002374:Catalase / Q000037:antagonists & inhibitors / Q000378:metabolism; D002462:Cell Membrane / Q000737:chemistry / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D005290:Ferric Compounds / Q000737:chemistry / Q000633:toxicity*; D005618:Fresh Water / Q000737:chemistry; D005980:Glutathione Reductase / Q000037:antagonists & inhibitors / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D058130:Mougeotia / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D053758:Nanoparticles / Q000737:chemistry / Q000633:toxicity*; D017382:Reactive Oxygen Species / Q000819:agonists / Q000378:metabolism; D018030:Silver Compounds / Q000737:chemistry / Q000633:toxicity*; D013440:Sulfides / Q000737:chemistry / Q000633:toxicity*; D013482:Superoxide Dismutase / Q000037:antagonists & inhibitors / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000633:toxicity*
chemical_list: D020418:Algal Proteins; D019187:Cadmium Compounds; D005290:Ferric Compounds; D017382:Reactive Oxygen Species; D018030:Silver Compounds; D013440:Sulfides; D014874:Water Pollutants, Chemical; C034939:cadmium sulfide; C000499:ferric oxide; C013251:silver sulfide; D002374:Catalase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase
keywords: Cadmium sulfide nanoparticles; Iron oxide nanoparticles; Mougeotia sp.; Nanocomposite; Silver sulfide nanoparticles; Toxicity