title: Papillary tumor of the pineal region. Report of two cases and literature review.
abstract: Papillary tumor of the pineal region (PTPR) was introduced to the WHO classification in 2007. This rare tumor of little known natural history and unpredictable behavior was described in fewer than 100 cases. Its optimal treatment is not established yet. We report another two cases of PTPR in whom tumors were totally removed via supracerebellar infratentorial approach and both were treated with radiotherapy. In a 37-year-old man the operation was delayed 6 years after the first tumor diagnosis and subsequent shunt placement. He has no complaints 10 years after the onset of the disease. A 45-year-old woman has no complaints 24 months after surgery. Our experience and the data from literature indicate that a total tumor removal is the major prognostic factor.
authors.affiliation: Department of Neurosurgery, Military Institute of Medicine, Warszawa, Poland. Electronic address: koziarski@plw.pl.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Koziarski
authors.affiliation: Department of Pathology, Military Institute of Medicine, Warszawa, Poland.
authors.forename: Bartłomiej
authors.initials: B
authors.lastname: Grala
authors.affiliation: Department of Radiology, Military Institute of Medicine, Warszawa, Poland.
authors.forename: Ewa
authors.initials: E
authors.lastname: Skrobowska
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000473:pathology*; D002291:Carcinoma, Papillary / Q000473:pathology*; D005260:Female; D006801:Humans; D007633:Keratins / Q000378:metabolism; D019394:Ki-67 Antigen / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010751:Phosphopyruvate Hydratase / Q000378:metabolism; D010870:Pineal Gland / Q000473:pathology*
chemical_list: D019394:Ki-67 Antigen; D007633:Keratins; D010751:Phosphopyruvate Hydratase
keywords: Papillary; Pineal; Tumor