title: Synthesis of YF3: Yb, Er upconverting nanofluorophores using chitosan and their cytotoxicity in MCF-7 cells.
abstract: In this work, we described one pot hydrothermal synthesis of surface modified water soluble YF3: Yb, Er upconverting nanofluorophores (UCNFs) using natural biopolymer chitosan. The obtained nanocrystals have undergone X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), high resolution transmission electron microscopy (HRTEM) and photoluminescence (PL) studies. The nanoparticles possess uniform particle size distribution with average size about 27 nm. The cytotoxicity results revealed that the chitosan capped nanoparticles exhibit excellent biocompatibility in human breast cancer cells. In conclusion, the water soluble chitosan capped YF3: Yb, Er nanoparticles could be used as a potential candidate in bio-imaging and therapeutic applications.
authors.affiliation: Nanophotonics and Nanoelectronics Research Laboratory, Centre for Nanoscience and Technology, Madanjeet School of Green Energy Technologies, Pondicherry University, Kalapet, Puducherry - 605014, India.
authors.forename: Sethuraman
authors.initials: S
authors.lastname: Gayathri
authors.affiliation: Nanophotonics and Nanoelectronics Research Laboratory, Centre for Nanoscience and Technology, Madanjeet School of Green Energy Technologies, Pondicherry University, Kalapet, Puducherry - 605014, India.
authors.forename: Oriparambil Sivaraman Nirmal
authors.initials: OS
authors.lastname: Ghosh
authors.affiliation: Nanophotonics and Nanoelectronics Research Laboratory, Centre for Nanoscience and Technology, Madanjeet School of Green Energy Technologies, Pondicherry University, Kalapet, Puducherry - 605014, India. Electronic address: v_kasi@hotmail.com.
authors.forename: Annamraju Kasi
authors.initials: AK
authors.lastname: Viswanath
authors.affiliation: CSIR - Central Leather Research Institute, Regional Centre for Extension and Development, Leather Complex, Jalandhar, Punjab - 144021, India.
authors.forename: P
authors.initials: P
authors.lastname: Sudhakara
authors.affiliation: Department of Chemical Engineering, Kyung Hee University, Global Campus, Seocheon - dong, Giheung - gu, Yongin - si Gyeonggi - do, Suwon - 446701, South Korea.
authors.forename: M Jeevan Kumar
authors.initials: MJ
authors.lastname: Reddy
authors.affiliation: Department of Chemical Engineering, Kyung Hee University, Global Campus, Seocheon - dong, Giheung - gu, Yongin - si Gyeonggi - do, Suwon - 446701, South Korea.
authors.forename: A M
authors.initials: AM
authors.lastname: Shanmugharaj
mesh_terms: D016923:Cell Death / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D048271:Chitosan / Q000494:pharmacology*; D004871:Erbium / Q000494:pharmacology*; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D008163:Luminescent Measurements; D061986:MCF-7 Cells; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D013052:Spectrometry, X-Ray Emission; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction; D015018:Ytterbium / Q000494:pharmacology*
chemical_list: D005456:Fluorescent Dyes; D004871:Erbium; D048271:Chitosan; D015018:Ytterbium
keywords: Chitosan capping; Cytotoxicity; Nanofluorophore