title: Indications for the HPV vaccine in adolescents: a review of the literature.
abstract: BACKGROUND
  The vaccine against human papillomavirus (HPV) was created to abrogate the risk that the virus presents for the development of cervical cancers. The prevalence of HPV infection among healthy individuals is significant (20%). We performed a review of the literature published in the period from 2008 to 2012 regarding the use of the vaccine against HPV specifically in adolescents.
  
  
  METHODS
  The articles were selected from a search of the PubMed database with the key words "vaccine", "HPV" and "adolescent". This search identified 576 articles; based on readings of the titles and abstracts, the list of included article was reduced to 42.
  
  
  RESULTS
  We observed that the majority of authors are in favor of the vaccine for adolescents particularly females.
  
  
  CONCLUSIONS
  Recommending the use of the HPV vaccine and other vaccines represents an attempt to broaden the reach of these vaccines among both sexes of the adolescent population. Vaccination is a strategy for the prevention of pre-cancerous lesions in the genital and oropharyngeal regions.
authors.affiliation: Oral Oncology Center, Department of Pathology and Clinical Propaedeutics, Araçatuba School of Dentistry, UNESP - Univ Estadual Paulista, Araçatuba, SP, Brazil.
authors.forename: Gláucia Resende
authors.initials: GR
authors.lastname: Soares
authors.affiliation: Oral Oncology Center, Department of Pathology and Clinical Propaedeutics, Araçatuba School of Dentistry, UNESP - Univ Estadual Paulista, Araçatuba, SP, Brazil.
authors.forename: Rúbia da Rocha
authors.initials: Rda R
authors.lastname: Vieira
authors.affiliation: Department of Dental Materials and Prosthodontics, Araçatuba School of Dentistry, UNESP - Univ Estadual Paulista, Araçatuba, SP, Brazil.
authors.forename: Eduardo Piza
authors.initials: EP
authors.lastname: Pellizzer
authors.affiliation: Oral Oncology Center, Department of Pathology and Clinical Propaedeutics, Araçatuba School of Dentistry, UNESP - Univ Estadual Paulista, Araçatuba, SP, Brazil. Electronic address: miyahara@foa.unesp.br.
authors.forename: Glauco Issamu
authors.initials: GI
authors.lastname: Miyahara
mesh_terms: D000293:Adolescent; D005260:Female; D005833:Genital Neoplasms, Female / Q000517:prevention & control*; D005834:Genital Neoplasms, Male / Q000517:prevention & control*; D006801:Humans; D008297:Male; D009959:Oropharyngeal Neoplasms / Q000517:prevention & control*; D030361:Papillomavirus Infections / Q000150:complications* / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000008:administration & dosage*; D014611:Vaccination
chemical_list: D053918:Papillomavirus Vaccines
keywords: Adolescent; HPV; Vaccine