title: Physical function and disability in older adults with diabetes.
abstract: Functional decline and physical disability are an important clinical and public health problem in older adults because they are associated with loss of independence, nursing home admission, and mortality. Several impairments and comorbidities related to or associated with diabetes are potential disabling conditions that could account for the excess risk of disability. But in most studies, no single condition explains this association. Accelerated loss of muscle strength is a potential mediator in the disabling effect of diabetes. Because some diabetes-related comorbidities are potential modifiable risk factors, preventing and reducing the excess risk of disability associated with diabetes needs further study.
authors.affiliation: Section of Geriatrics, Department of Internal Medicine, Yale School of Medicine, 367 Cedar Street, Harkness Building A, Room 317A, New Haven, CT 06520, USA. Electronic address: nathalie.derekeneire@yale.edu.
authors.forename: Nathalie
authors.initials: N
authors.lastname: de Rekeneire
authors.affiliation: Section of Internal Medicine, Gerontology and Clinical, Nutrition, Department of Medical Sciences, Azienda Ospedaliero-Universitaria di Ferrara U.O. Medicina Interna Universitaria, University of Ferrara, Via Aldo Moro 8, 1B1 Stanza 1.35.30, Ferrara 44124, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Volpato
mesh_terms: D000203:Activities of Daily Living; D000367:Age Factors; D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000503:physiopathology*; D006801:Humans; D051346:Mobility Limitation; D009043:Motor Activity / Q000502:physiology*; D053580:Muscle Strength / Q000502:physiology*; D012307:Risk Factors
keywords: Aging; Diabetes; Disability; Functional limitation; Muscle strength