title: [Nutrition of pregnant women: consequences for fetal growth and adult diseases].
abstract: The developmental origins of human adult disease are thought to be secondary to a perturbation of the embryonic or fetal development, which leads to metabolic disorders such as diabetes or hypertension at adulthood. Maternal undernutrition or overnutrition, repeated glucocorticosteroids administered to the mother, or placental dysfunction are the most frequently considered causal factors. Therefore, it is necessary that the pediatrician is aware of these phenomena, as this knowledge may contribute to the prevention of adult diseases. Little is known yet, however, on the pathophysiological or epigenetic mechanisms that lead to theses observations, and more studies are needed both in humans and animal models.
authors.affiliation: Service de gynécologie obstétrique et médecine de la reproduction, hôpital Foch, 40, rue Worth, 92120 Suresnes, France; EA2493, UFR des sciences de la santé Simone-Veil, UVSQ, 78180 Montigny-le-Bretonneux, France.
authors.forename: M
authors.initials: M
authors.lastname: Weber
authors.affiliation: Service de gynécologie obstétrique et médecine de la reproduction, hôpital Foch, 40, rue Worth, 92120 Suresnes, France; EA2493, UFR des sciences de la santé Simone-Veil, UVSQ, 78180 Montigny-le-Bretonneux, France.
authors.forename: J-M
authors.initials: JM
authors.lastname: Ayoubi
authors.affiliation: Service de gynécologie obstétrique et médecine de la reproduction, hôpital Foch, 40, rue Worth, 92120 Suresnes, France; EA2493, UFR des sciences de la santé Simone-Veil, UVSQ, 78180 Montigny-le-Bretonneux, France. Electronic address: o.picone@hopital-foch.org.
authors.forename: O
authors.initials: O
authors.lastname: Picone
mesh_terms: D000328:Adult; D044127:Epigenesis, Genetic; D005260:Female; D047109:Fetal Development; D006801:Humans; D039382:Maternal Nutritional Physiological Phenomena; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects