title: Herlyn-Werner-Wunderlich syndrome: merits of sonographic and magnetic resonance imaging for accurate diagnosis and patient management in 13 cases.
abstract: OBJECTIVE
  To review the main sonographic and magnetic resonance imaging manifestations of Herlyn-Werner-Wunderlich syndrome, characterized by uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis, and to discuss the value of techniques for its diagnosis and treatment.
  
  
  METHODS
  Thirteen patients with Herlyn-Werner-Wunderlich syndrome referred to our department with acute abdomen were identified for the period from 2009-2012.
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  Two tertiary academic centers.
  
  
  METHODS
  None.
  
  
  METHODS
  The evaluation of the clinical features, ultrasonography and magnetic resonance imaging findings, and the treatment protocols.
  
  
  RESULTS
  Ultrasonographic evaluation of didelphic or double uterus in 10 and bicornuate-bicollis uterus in 3 patients with hematocolpos or hematometrocolpos associated with agenesis of the ipsilateral kidney revealed the diagnosis. In 10 patients, magnetic resonance imaging provided extra information. In 1 patient, a 25-week pregnancy was additionally detected and follow-up was suggested. Seven patients underwent surgical excision of the septum and drainage of the obstructed vagina. Total hysterectomy and hemicolpectomy were performed in 1 patient with 2 children suffering from severe chronic pelvic pain due to pelvic inflammatory disease.
  
  
  CONCLUSIONS
  Despite its rarity, accurate diagnosis and morphologic description of Herlyn-Werner-Wunderlich syndrome with radiologic modalities are of importance in relieving the clinical complaints by enabling the suitable surgical treatment to be identified.
authors.affiliation: Department of Radiology, Yüzüncü Yıl University, School of Medicine, Van, Turkey.
authors.forename: Alpaslan
authors.initials: A
authors.lastname: Yavuz
authors.affiliation: Department of Radiology, Yüzüncü Yıl University, School of Medicine, Van, Turkey.
authors.forename: Aydın
authors.initials: A
authors.lastname: Bora
authors.affiliation: Department of Obstetrics and Gynecology, Gazi University, School of Medicine, Ankara, Turkey. Electronic address: mkurdoglu@gazi.edu.tr.
authors.forename: Mertihan
authors.initials: M
authors.lastname: Kurdoğlu
authors.affiliation: Department of Radiology, Dicle University, School of Medicine, Diyarbakır, Turkey.
authors.forename: Cemil
authors.initials: C
authors.lastname: Goya
authors.affiliation: Department of Obstetrics and Gynecology, Yüzüncü Yıl University, School of Medicine, Van, Turkey.
authors.forename: Zehra
authors.initials: Z
authors.lastname: Kurdoğlu
authors.affiliation: Department of Radiology, Yüzüncü Yıl University, School of Medicine, Van, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Beyazal
authors.affiliation: Department of Radiology, Yüzüncü Yıl University, School of Medicine, Van, Turkey.
authors.forename: Zülküf
authors.initials: Z
authors.lastname: Akdemir
mesh_terms: D000006:Abdomen, Acute / Q000175:diagnosis* / Q000601:surgery; D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000601:surgery; D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006399:Hematocolpos / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007044:Hysterectomy; D007668:Kidney / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000601:surgery; D008279:Magnetic Resonance Imaging; D000292:Pelvic Inflammatory Disease / Q000150:complications; D017699:Pelvic Pain / Q000209:etiology; D011247:Pregnancy; D012189:Retrospective Studies; D013577:Syndrome; D014463:Ultrasonography; D014599:Uterus / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D014621:Vagina / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D055815:Young Adult
keywords: Herlyn-Werner-Wunderlich syndrome; Magnetic resonance imaging; Obstructed hemivagina; Ultrasonography; Uterus didelphys