title: A case of necrotizing vasculitis with panniculitis, during sorafenib treatment for hepatocellular carcinoma, appeared in disease progression.
abstract: Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and is the third most common cause of death from cancer. Sorafenib is the only drug which improves survival in first line advanced HCC. Sorafenib has been associated with several dermatologic toxicities and toxic effects have been related to a better treatment response. We report the case of a well-circumscribed panniculitis and necrotizing vasculitis due to sorafenib, appeared in disease progression in a man affected by advanced HCC.
authors.affiliation: 1 Department of Oncology and Advanced Technologies, Oncology Unit, 2 Department of Oncology and Advanced Technologies, Patology Unit, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Panebianco
authors.affiliation: 1 Department of Oncology and Advanced Technologies, Oncology Unit, 2 Department of Oncology and Advanced Technologies, Patology Unit, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy.
authors.forename: Moira
authors.initials: M
authors.lastname: Ragazzi
authors.affiliation: 1 Department of Oncology and Advanced Technologies, Oncology Unit, 2 Department of Oncology and Advanced Technologies, Patology Unit, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy.
authors.forename: Nuria Maria
authors.initials: NM
authors.lastname: Asensio
authors.affiliation: 1 Department of Oncology and Advanced Technologies, Oncology Unit, 2 Department of Oncology and Advanced Technologies, Patology Unit, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Pagano
authors.affiliation: 1 Department of Oncology and Advanced Technologies, Oncology Unit, 2 Department of Oncology and Advanced Technologies, Patology Unit, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Gnoni
authors.affiliation: 1 Department of Oncology and Advanced Technologies, Oncology Unit, 2 Department of Oncology and Advanced Technologies, Patology Unit, Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico, Reggio Emilia, Italy.
authors.forename: Corrado
authors.initials: C
authors.lastname: Boni
keywords: Sorafenib; hepatocellular carcinoma (HCC); panniculitis