title: Catheter-related bacteremia by Cupriavidus metallidurans.
abstract: Cupriavidus bacteremia is a rare infection and identification of the pathogen is difficult. We present four cases of bacteremia by Cupriavidus metallidurans that were initially identified to the genus level by both Bruker and Vitek matrix-assisted laser desorption ionization-time of flight mass spectrometry and later identified to the species level by 16S rRNA gene sequencing. To our knowledge, these are the first cases of C. metallidurans catheter-related infections. Patients were successfully treated with antibiotic therapy and catheter removal.
authors.affiliation: Institutes of Microbiology, Catholic University School of Medicine, 00168 Roma, Italy.
authors.forename: Tiziana
authors.initials: T
authors.lastname: D'Inzeo
authors.affiliation: Institutes of Microbiology, Catholic University School of Medicine, 00168 Roma, Italy.
authors.forename: Rosaria
authors.initials: R
authors.lastname: Santangelo
authors.affiliation: Institutes of Microbiology, Catholic University School of Medicine, 00168 Roma, Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Fiori
authors.affiliation: Institutes of Microbiology, Catholic University School of Medicine, 00168 Roma, Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: De Angelis
authors.affiliation: Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
authors.forename: Viola
authors.initials: V
authors.lastname: Conte
authors.affiliation: Institutes of Microbiology, Catholic University School of Medicine, 00168 Roma, Italy.
authors.forename: Alessia
authors.initials: A
authors.lastname: Giaquinto
authors.affiliation: Institutes of Microbiology, Catholic University School of Medicine, 00168 Roma, Italy.
authors.forename: Ivana
authors.initials: I
authors.lastname: Palucci
authors.affiliation: Institutes of Infectious Diseases, Catholic University School of Medicine, 00168 Roma, Italy.
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Scoppettuolo
authors.affiliation: Institutes of Microbiology, Catholic University School of Medicine, 00168 Roma, Italy.
authors.forename: Viviana
authors.initials: V
authors.lastname: Di Florio
authors.affiliation: Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
authors.forename: Tommaso
authors.initials: T
authors.lastname: Giani
authors.affiliation: Institutes of Microbiology, Catholic University School of Medicine, 00168 Roma, Italy. Electronic address: msanguinetti@rm.unicatt.it.
authors.forename: Maurizio
authors.initials: M
authors.lastname: Sanguinetti
authors.affiliation: Department of Medical Biotechnologies, University of Siena, 53100 Siena, Italy; Department of Experimental and Clinical Medicine, University of Florenc, 50134 Florence, Italy; Clinical Microbiology and Virology Unit, Florence Careggi University Hospital, 50134 Florence, Italy.
authors.forename: Gian Maria
authors.initials: GM
authors.lastname: Rossolini
authors.affiliation: Institutes of Microbiology, Catholic University School of Medicine, 00168 Roma, Italy.
authors.forename: Teresa
authors.initials: T
authors.lastname: Spanu
mesh_terms: D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D055499:Catheter-Related Infections / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D049921:Cupriavidus / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity*; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010878:Piperacillin / Q000627:therapeutic use; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods; D000078142:Tazobactam
chemical_list: D010397:Penicillanic Acid; D000078142:Tazobactam; D010878:Piperacillin
keywords: Catheter-related bacteremia; Cupriavidus