title: Intra-abdominal Infections.
abstract: Intra-abdominal infections are multifactorial, but all require prompt identification, diagnosis, and treatment. Resuscitation, early antibiotic administration, and source control are crucial. Antibiotic administration should initially be broad spectrum and target the most likely pathogens. When cultures are available, antibiotics should be narrowed and limited in duration. The method of source control depends on the anatomic site, site accessibility, and the patient's clinical condition. Patient-specific factors (advanced age and chronic medical conditions) as well as disease-specific factors (health care-associated infections and inability to obtain source control) combine to affect patient morbidity and mortality.
authors.affiliation: Division of Trauma & Critical Care Surgery, Department of Surgery, Maricopa Medical Center, 2601 East Roosevelt Street, Phoenix, AZ 85008, USA.
authors.forename: Gina R
authors.initials: GR
authors.lastname: Shirah
authors.affiliation: Trauma Department, West Valley Hospital, 13677 W McDowell Road, Goodyear, AZ 85395, USA. Electronic address: pjoneill@abrazohealth.com.
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: O'Neill
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003646:Debridement; D006801:Humans; D059413:Intraabdominal Infections / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D012151:Resuscitation / Q000379:methods
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotics; Complicated intra-abdominal infections; Damage control surgery; Resuscitation; Source control; Systemic inflammatory response syndrome; Uncomplicated intra-abdominal infections