title: The rest of the story: the microbiome and gastrointestinal infections.
abstract: Bacterial infectious diseases are studied primarily as a host-pathogen dyad. However it is increasingly apparent that the gut microbial community is an important participant in these interactions. The gut microbiota influences bacterial infections in a number of ways, including via bacterial metabolism, stimulation of host immunity and direct bacterial antagonism. This review focuses on recent findings highlighting the interplay between the gastrointestinal microbiota, its host and bacterial pathogens; and emphasizes how these interactions ultimately impact our understanding of infectious diseases.
authors.affiliation: Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.
authors.forename: Jhansi L
authors.initials: JL
authors.lastname: Leslie
authors.affiliation: Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA; Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: youngvi@umich.edu.
authors.forename: Vincent B
authors.initials: VB
authors.lastname: Young
mesh_terms: D005767:Gastrointestinal Diseases / Q000276:immunology / Q000382:microbiology* / Q000517:prevention & control; D041981:Gastrointestinal Tract / Q000382:microbiology*; D056265:Microbial Interactions; D064307:Microbiota