title: Changes in social functioning and circulating oxytocin and vasopressin following the migration to a new country.
abstract: Prior studies have reported associations between plasma oxytocin and vasopressin and markers of social functioning. However, because most human studies have used cross-sectional designs, it is unclear whether plasma oxytocin and vasopressin influences social functioning or whether social functioning modulates the production and peripheral release of these peptides. In order to address this question, we followed individuals who experienced major changes in social functioning subsequent to the migration to a new country. In this study, 59 new international students were recruited shortly after arrival in the host country and reassessed 2 and 5 months later. At each assessment participants provided information on their current social functioning and blood samples for oxytocin and vasopressin analysis. Results indicated that changes in social functioning were not related to changes in plasma oxytocin. Instead, baseline oxytocin predicted changes in social relationship satisfaction, social support, and loneliness over time. In contrast, plasma vasopressin changed as a function of social integration. Baseline vasopressin was not related to changes in social functioning over time. These results emphasize the different roles of plasma oxytocin and vasopressin in responses to changes in social functioning in humans.
authors.affiliation: Department of Psychology, Concordia University, Montréal, Canada; Center for Clinical Research in Health, Concordia University, Montréal, Canada. Electronic address: jp.gouin@concordia.ca.
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Gouin
authors.affiliation: Department of Psychiatry, University of NC at Chapel Hill, USA.
authors.forename: Hossein
authors.initials: H
authors.lastname: Pournajafi-Nazarloo
authors.affiliation: Department of Psychiatry, University of NC at Chapel Hill, USA.
authors.forename: C Sue
authors.initials: CS
authors.lastname: Carter
mesh_terms: D000328:Adult; D054242:Emigrants and Immigrants / Q000523:psychology*; D005260:Female; D006801:Humans; D007398:Interpersonal Relations; D008132:Loneliness / Q000523:psychology; D008137:Longitudinal Studies; D008297:Male; D010121:Oxytocin / Q000097:blood*; D013223:Statistics as Topic; D013315:Stress, Psychological / Q000097:blood / Q000209:etiology / Q000523:psychology; D011795:Surveys and Questionnaires; D014667:Vasopressins / Q000097:blood*; D055815:Young Adult
chemical_list: D014667:Vasopressins; D010121:Oxytocin
keywords: Loneliness; Longitudinal; Oxytocin; Relationship satisfaction; Social functioning; Social integration; Social support; Vasopressin