title: Correlation among lens opacities classification system III grading, visual function index-14, pentacam nucleus staging, and objective scatter index for cataract assessment.
abstract: OBJECTIVE
  To investigate the relationship among Lens Opacities Classification System III (LOCS III) grading score, Visual Function Index-14 (VF-14) score, average lens density by the Pentacam Nucleus Staging system, and the objective scatter index measured by the Optical Quality Analysis System in age-related cataract patients.
  
  
  METHODS
  Prospective, single-center, cross-sectional study.
  
  
  METHODS
  Thirty-six subjects (60 eyes) with age-related cataract were recruited. Subjects with any corneal anomaly potentially affecting intraocular scatter were excluded. The best-corrected visual acuity (BCVA), LOCS III nuclear opalescence score and cortical cataract score, VF-14 score, average lens density, and objective scatter index were obtained. Correlations among these parameters were analyzed.
  
  
  RESULTS
  The LOCS III nuclear opalescence score was correlated with the BCVA (r = 0.438; P = .001), objective scatter index (r = 0.543; P < .001), and average lens density (r = 0.621; P < .001). The objective scatter index was also correlated with the BCVA (r = 0.779; P < .001) and the average lens density (r = 0.320; P = .013). The VF-14 score had the strongest correlation with the objective scatter index (r = -0.712; P < .001). The difference between groups with objective scatter index<3.0 and ≥3.0 was significant with regard to BCVA, average lens density, LOCS III nuclear opalescence score, and VF-14 score.
  
  
  CONCLUSIONS
  LOCS III grading remains an economical and effective method to assess lens opacities, especially in the formation of early cortex cataracts. The objective scatter index can be a useful parameter to objectively analyze the correlation between ocular examination findings and patient concerns. Furthermore, the objective scatter index scores ≥3.0 can be a possible objective cut-off for preoperative decision making.
authors.affiliation: The Eye Hospital of Wenzhou Medical University, Wenzhou, China.
authors.forename: An-Peng
authors.initials: AP
authors.lastname: Pan
authors.affiliation: The Eye Hospital of Wenzhou Medical University, Wenzhou, China.
authors.forename: Qin-Mei
authors.initials: QM
authors.lastname: Wang
authors.affiliation: The Eye Hospital of Wenzhou Medical University, Wenzhou, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Huang
authors.affiliation: The Eye Hospital of Wenzhou Medical University, Wenzhou, China.
authors.forename: Jin-Hai
authors.initials: JH
authors.lastname: Huang
authors.affiliation: The Eye Hospital of Wenzhou Medical University, Wenzhou, China.
authors.forename: Fang-Jun
authors.initials: FJ
authors.lastname: Bao
authors.affiliation: The Eye Hospital of Wenzhou Medical University, Wenzhou, China. Electronic address: yaybetter@hotmail.com.
authors.forename: A-Yong
authors.initials: AY
authors.lastname: Yu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000145:classification* / Q000175:diagnosis / Q000503:physiopathology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007907:Lens Nucleus, Crystalline / Q000473:pathology*; D008027:Light; D008297:Male; D008875:Middle Aged; D010781:Photography / Q000379:methods*; D011446:Prospective Studies; D012542:Scattering, Radiation; D018434:Sickness Impact Profile; D013223:Statistics as Topic; D011795:Surveys and Questionnaires; D014792:Visual Acuity / Q000502:physiology*