title: Single site laparoscopy for fertility preservation: a cohort study.
abstract: OBJECTIVE
  To compare operative and postoperative results of ovarian cortex retrieval by conventional laparoscopy (1cm umbilical site and 3 accessory 5-mm-reusable working ports) (HASS) versus single site laparoscopy (SSL).
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  Fertility Preservation Programme at La Fe University Hospital-University of Valencia, Valencia, Spain, 2011 to 2012. Fertility Preservation Programme at La Fe University Hospital of Valencia, Valencia, Spain.
  
  
  METHODS
  Twenty-one patients with cancer (breast cancer: n = 17; Hodgkin's lymphoma: n = 3; and non-Hodgkin's lymphoma: n = 1).
  
  
  METHODS
  Ovarian cortex retrieval either by conventional laparoscopy using an umbilical Hasson port and 3 accessory ports (HASS group: n = 11) or by SSL (SSL group: n = 10).
  
  
  RESULTS
  Operative length, blood loss, postoperative pain (visual analog scale for pain at 6, 24, and 48 hours), need of additional analgesia, quality of life (European Quality of Life-5 Dimensions), cosmesis of the scar, and patient's self-perception were assessed at 24 and 48 hours and 3 months after surgery. Baseline characteristics were similar between groups. Estimated blood loss, operative length, and postoperative pain did not differ between groups. The start of chemotherapy was not delayed in either group, and cosmesis and image self-perception were also similar.
  
  
  CONCLUSIONS
  The SSL approach can be considered a safe option compared with the classic multisite approach.
authors.affiliation: Unidad de preservación de la fertilidad, Área de Salud de la Mujer, Hospital Universitario La Fe, Valencia, Spain.
authors.forename: María José
authors.initials: MJ
authors.lastname: Núñez Valera
authors.affiliation: Unidad de preservación de la fertilidad, Área de Salud de la Mujer, Hospital Universitario La Fe, Valencia, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Padilla Iserte
authors.affiliation: Unidad de preservación de la fertilidad, Área de Salud de la Mujer, Hospital Universitario La Fe, Valencia, Spain.
authors.forename: Gema
authors.initials: G
authors.lastname: Higueras García
authors.affiliation: Grupo de Investigación en Medicina Reproductiva, Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
authors.forename: Sonia
authors.initials: S
authors.lastname: Herraiz
authors.affiliation: Unidad de preservación de la fertilidad, Área de Salud de la Mujer, Hospital Universitario La Fe, Valencia, Spain.
authors.forename: José María
authors.initials: JM
authors.lastname: Rubio
authors.affiliation: Unidad de preservación de la fertilidad, Área de Salud de la Mujer, Hospital Universitario La Fe, Valencia, Spain; Grupo de Investigación en Medicina Reproductiva, Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
authors.forename: Mónica
authors.initials: M
authors.lastname: Romeu Villarroya
authors.affiliation: Unidad de preservación de la fertilidad, Área de Salud de la Mujer, Hospital Universitario La Fe, Valencia, Spain; Grupo de Investigación en Medicina Reproductiva, Instituto de Investigación Sanitaria La Fe, Valencia, Spain; Instituto Valenciano de Infertilidad (IVI), Valencia, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Pellicer
authors.affiliation: Unidad de preservación de la fertilidad, Área de Salud de la Mujer, Hospital Universitario La Fe, Valencia, Spain; Grupo de Investigación en Medicina Reproductiva, Instituto de Investigación Sanitaria La Fe, Valencia, Spain. Electronic address: cdiaz_med@yahoo.fr.
authors.forename: César
authors.initials: C
authors.lastname: Díaz-García
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D059247:Fertility Preservation / Q000379:methods; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D010053:Ovary / Q000601:surgery*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000453:epidemiology*; D011446:Prospective Studies; D011788:Quality of Life; D013030:Spain / Q000453:epidemiology; D016896:Treatment Outcome; D014472:Umbilicus / Q000601:surgery*
keywords: Cosmesis; Fertility preservation; Laparoscopy; Oophorectomy; Ovary