title: Hirschsprung disease and anorectal malformation.
abstract: Hirschsprung disease and Anorectal Malformations are congenital disorders presenting in neonates with distal intestinal obstruction. Hirschsprung disease is associated with a functional distal bowel obstruction resulting from the abnormal development of the enteric nervous system and ensuing aganglionosis of the distal gut. Anorectal Malformations comprise a spectrum of anatomical anomalies causing a mechanical bowel obstruction. Both conditions are frequently associated with congenital abnormalities/syndromes, which require careful assessment and evaluation. Surgical intervention is usually required for both conditions with careful preparation and meticulous technique. Long-term follow-up allows early identification and treatment of potentially debilitating symptoms, which include faecal incontinence.
authors.affiliation: Department of Paediatric Surgery, Leeds General Infirmary, Leeds, UK. Electronic address: charlotte.vw@hotmail.co.uk.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Wetherill
authors.affiliation: Department of Paediatric Surgery, Leeds General Infirmary, Leeds, UK. Electronic address: Jonathan.sutcliffe@leedsth.nhs.uk.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Sutcliffe
mesh_terms: D000071056:Anorectal Malformations; D001006:Anus, Imperforate / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D017408:Guidelines as Topic; D006627:Hirschsprung Disease / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D007415:Intestinal Obstruction / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography
keywords: Anorectal malformation; Congenital abnormalities; Hirschsprung disease; Neonatal intestinal obstruction