title: Ultra performance liquid chromatography-tandem mass spectrometry for the determination of amicarthiazol residues in soil and water samples.
abstract: A reliable and rapid method has been optimized to determine the residue of amicarthiazol in soil and environmental water samples. After extraction and evaporation, the extraction was carried out with solid phase extraction (SPE) cleanup using HLB cartridge (only soil samples) and for the quantitative determination by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The resulting residues of amicarthiazol were analyzed by a gradient separation performed on a UPLC system with a C18 column, methanol and water containing 0.1% (v v(-1)) formic acid as the mobile phase in the mode of electrospray positive ionization (ESI(+)) and multiple reaction monitoring (MRM). Results showed that the recoveries for spiked samples were 74.4-97.1% and 72.1-109.9% for soil and water, respectively, with the relative standard deviation (RSD) less than 10.2% when fortified at 10, 100 and 1000μgL(-1). The limits of detection (LODs) and the limits of quantification (LOQs) for matrix matched standards ranged from 0.073-0.425μgL(-1) and 0.243-1.42μgL(-1). The intra-day precision (n=5) and the inter-day precision over 10 days (n=10) for the amicarthiazol in soils and water samples spiked at 100μgL(-1) was 7.9% and 15.9%, respectively. Results indicated that the developed method could be a helpful tool for the controlling and monitoring of the risks posed by amicarthiazol to human health and environment safety.
authors.affiliation: Institute of Pesticide and Environmental Toxicology, Zhejiang University, 268 Kaixuan Road, Hangzhou 310029, Zhejiang, China.
authors.forename: Wen-jun
authors.initials: WJ
authors.lastname: Gui
authors.affiliation: Zhenjiang Institute of Termite Control, 65 Yunhe Road, Zhengjiang 212003, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Tian
authors.affiliation: Institute of Pesticide and Environmental Toxicology, Zhejiang University, 268 Kaixuan Road, Hangzhou 310029, Zhejiang, China.
authors.forename: Chun-xia
authors.initials: CX
authors.lastname: Tian
authors.affiliation: Institute of Pesticide and Environmental Toxicology, Zhejiang University, 268 Kaixuan Road, Hangzhou 310029, Zhejiang, China.
authors.forename: Shu-ying
authors.initials: SY
authors.lastname: Li
authors.affiliation: Institute of Pesticide and Environmental Toxicology, Zhejiang University, 268 Kaixuan Road, Hangzhou 310029, Zhejiang, China.
authors.forename: You-ning
authors.initials: YN
authors.lastname: Ma
authors.affiliation: Institute of Pesticide and Environmental Toxicology, Zhejiang University, 268 Kaixuan Road, Hangzhou 310029, Zhejiang, China. Electronic address: zhugn@zju.edu.cn.
authors.forename: Guo-nian
authors.initials: GN
authors.lastname: Zhu
mesh_terms: D000813:Anilides / Q000032:analysis*; D002853:Chromatography, Liquid / Q000379:methods*; D004350:Drug Residues / Q000032:analysis; D005659:Fungicides, Industrial / Q000032:analysis; D012989:Soil Pollutants / Q000032:analysis*; D052616:Solid Phase Extraction; D053719:Tandem Mass Spectrometry / Q000379:methods*; D013844:Thiazoles / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D000813:Anilides; D005659:Fungicides, Industrial; D012989:Soil Pollutants; D013844:Thiazoles; D014874:Water Pollutants, Chemical; C511341:amicarthiazol
keywords: Amicarthiazol; Soil; Solid phase extraction; Ultra performance liquid chromatography-tandem mass spectrometry; Water