title: Neuro-ophthalmic manifestations of cerebellar disease.
abstract: The cerebellum is responsible for refining ocular movements, thereby guaranteeing the best possible visual acuity and clarity despite changes in body or head positions or movement of the object of interest. The cerebellum is involved in the control of all eye movements, in their real-time, immediate modulation, and in their long-term adaptive calibration. The flocculus-paraflocculus complex and the caudal vermis (nodulus and uvula) together constitute the vestibulocerebellum. Lesions affecting these different regions give rise to 3 principal clinical cerebellar syndromes. This article discusses the various neuro-ophthalmic manifestations of various cerebellar disorders, as well as some therapeutic options for oscillopsia.
authors.affiliation: Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
authors.forename: Shin C
authors.initials: SC
authors.lastname: Beh
authors.affiliation: Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
authors.forename: Teresa C
authors.initials: TC
authors.lastname: Frohman
authors.affiliation: Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA; Department of Ophthalmology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA. Electronic address: elliot.frohman@utsouthwestern.edu.
authors.forename: Elliot M
authors.initials: EM
authors.lastname: Frohman
mesh_terms: D002526:Cerebellar Diseases / Q000150:complications*; D005128:Eye Diseases / Q000209:etiology*; D005133:Eye Movements / Q000502:physiology; D006801:Humans; D009760:Nystagmus, Physiologic / Q000502:physiology; D012027:Reflex, Vestibulo-Ocular / Q000502:physiology
keywords: Cerebellum; Eye movements; Neuro-ophthalmology; Nystagmus; Saccades; Smooth pursuit; Vergence; Vestibuloocular reflex