title: Custom facial reconstruction for osteosarcoma of the jaw.
abstract: Osteosarcoma accounts for most primary bone cancers in children and young adults. High-grade lesions are typically managed with a combination of chemotherapy and wide-margin surgical excision. Although this malignancy typically affects the metaphyseal region of long bones, it also can be seen in the axial skeleton. Of axial locations, tumors in the head and neck can be particularly troubling to treat. Segmental bone loss after resection of malignant mandibular tumors continues to present important challenges to the reconstructive surgeon. Recent advancements in 3-dimensional modeling have facilitated custom templates for patient-specific reconstructions. This report describes the case of a young woman with osteosarcoma of the mandible undergoing customized template composite facial reconstruction using a vascularized osteoseptocutaneous fibula flap.
authors.affiliation: Medical Student, Duke University School of Medicine, Durham, NC. Electronic address: alexander.lazarides@dm.duke.edu.
authors.forename: Alexander
authors.initials: A
authors.lastname: Lazarides
authors.affiliation: Associate Professor, Department of Surgery, Division of Plastic and Reconstructive Surgery, Duke University Medical Center, Durham, NC.
authors.forename: Detlev
authors.initials: D
authors.lastname: Erdmann
authors.affiliation: Associate Professor, Department of Surgery, Division of Plastic, Reconstructive, Maxillofacial, and Oral Surgery, Duke University Medical Center, Durham, NC.
authors.forename: David
authors.initials: D
authors.lastname: Powers
authors.affiliation: Associate Professor, Department of Surgery, Division of Orthopaedic Surgery, Duke University Medical Center, Durham, NC.
authors.forename: William
authors.initials: W
authors.lastname: Eward
mesh_terms: D000328:Adult; D005145:Face / Q000601:surgery*; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000601:surgery*; D012516:Osteosarcoma / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*