title: A randomized controlled study of the use of ProRoot mineral trioxide aggregate and Endocem as direct pulp capping materials.
abstract: BACKGROUND
  The purpose of the present study was to evaluate and compare the short-term clinical outcomes of direct pulp capping using ProRoot MTA (Dentsply, Tulsa, OK) or Endocem (Maruchi, Wonju, Korea) as capping materials in a prospective randomized controlled study.
  
  
  METHODS
  This study was conducted with subjects who were recruited from the pool of patients from the Department of Conservative Dentistry at the Dental College of Yonsei University, Seoul, Korea, between January and May 2013. Of the 48 teeth confirmed to be eligible for direct pulp capping, a total of 46 teeth were randomly assigned to either the ProRoot MTA or the Endocem group (23 teeth per group). Direct pulp capping was performed using these 2 materials, and clinical and radiographic evaluations were performed at 1, 2, 4, and 12 weeks after the treatments. Teeth with no response to pulp vitality test and those exhibiting clinical or radiographic signs and/or symptoms of irreversible pulpitis or pulp necrosis were considered to be failures.
  
  
  RESULTS
  Thirty-two patients (43 teeth) were examined at the 3-month follow-up (patient recall rate = 91.4%); 22 of these teeth were in the ProRoot MTA group, and 21 were in the Endocem group. The overall success rate was 93%, and the success rates in the ProRoot MTA and Endocem groups were 95.5% (21/22 teeth) and 90.5% (19/21 teeth), respectively. Statistical analyses of these success rates did not reveal any significant difference between the groups (P = .522).
  
  
  CONCLUSIONS
  In this randomized controlled study, no significant difference in the short-term clinical outcomes of direct pulp capping using ProRoot MTA or Endocem as the capping material was found. Furthermore, the favorable short-term outcome success rate of 93% indicates that direct pulp capping may be a reliable treatment for pulp exposure in adult teeth.
authors.affiliation: Department of Conservative Dentistry, Gangnam Severance Dental Hospital, College of Dentistry, Yonsei University, Seoul, South Korea. Electronic address: andyendo@yuhs.ac.
authors.forename: Minju
authors.initials: M
authors.lastname: Song
authors.affiliation: Microscope Center, Department of Conservative Dentistry and Oral Science Research Center, College of Dentistry, Yonsei University, Seoul, South Korea.
authors.forename: Minji
authors.initials: M
authors.lastname: Kang
authors.affiliation: Department of Conservative Dentistry, School of Dentistry, Pusan National University, Busan, South Korea.
authors.forename: Hyeon-Cheol
authors.initials: HC
authors.lastname: Kim
authors.affiliation: Microscope Center, Department of Conservative Dentistry and Oral Science Research Center, College of Dentistry, Yonsei University, Seoul, South Korea.
authors.forename: Euiseong
authors.initials: E
authors.lastname: Kim
mesh_terms: D000328:Adult; D000359:Aftercare; D000368:Aged; D017607:Aluminum Compounds / Q000627:therapeutic use*; D017610:Calcium Compounds / Q000627:therapeutic use*; D003738:Dental Cements / Q000627:therapeutic use; D003782:Dental Pulp / Q000187:drug effects; D003785:Dental Pulp Capping / Q000379:methods*; D003789:Dental Pulp Exposure / Q000628:therapy; D003790:Dental Pulp Necrosis / Q000188:drug therapy; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000627:therapeutic use*; D011446:Prospective Studies; D011671:Pulpitis / Q000188:drug therapy; D012387:Root Canal Filling Materials / Q000627:therapeutic use*; D012390:Root Canal Therapy / Q000379:methods*; D017640:Silicates / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D003738:Dental Cements; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C586519:endocem; C086631:mineral trioxide aggregate
keywords: Clinical outcome; Endocem; ProRoot MTA; direct pulp capping; randomized controlled study