title: Bilateral parotid gland metastases from carcinoma of the breast that presented 25 years after initial treatment.
abstract: We report a case of a 76-year-old woman with metastases to both parotid glands almost 25 years after mastectomy and chemotherapy for primary carcinoma of the breast. Immunohistochemical staining is invaluable in establishing the origin of metastatic deposits, in this case, expression of oestrogen receptors in a previously resected adenocarcinoma of the breast. The information can be used to target treatment accurately in selected cases of advanced malignancy.
authors.affiliation: Royal Sussex County Hospital, Brighton, United Kingdom. Electronic address: Miles.Duncan@bsuh.nhs.uk.
authors.forename: M
authors.initials: M
authors.lastname: Duncan
authors.affiliation: Royal Sussex County Hospital, Brighton, United Kingdom. Electronic address: Michael.Monteiro@bsuh.nhs.uk.
authors.forename: M
authors.initials: M
authors.lastname: Monteiro
authors.affiliation: Royal Sussex County Hospital, Brighton, United Kingdom. Electronic address: Mara.Quante@bsuh.nhs.uk.
authors.forename: M
authors.initials: M
authors.lastname: Quante
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology / Q000556:secondary*; D000368:Aged; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000473:pathology*; D017024:Chemotherapy, Adjuvant; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008408:Mastectomy / Q000379:methods; D010307:Parotid Neoplasms / Q000473:pathology / Q000556:secondary*; D011960:Receptors, Estrogen / Q000032:analysis; D013629:Tamoxifen / Q000627:therapeutic use
chemical_list: D018931:Antineoplastic Agents, Hormonal; D011960:Receptors, Estrogen; D013629:Tamoxifen
keywords: Bilateral parotid metastases; Breast adenocarcinoma; Cytokeratins; Immunohistochemistry; Letrozole; Tamoxifen