title: Analysis of EEG activity in response to binaural beats with different frequencies.
abstract: When two coherent sounds with nearly similar frequencies are presented to each ear respectively with stereo headphones, the brain integrates the two signals and produces a sensation of a third sound called binaural beat (BB). Although earlier studies showed that BB could influence behavior and cognition, common agreement on the mechanism of BB has not been reached yet. In this work, we employed Relative Power (RP), Phase Locking Value (PLV) and Cross-Mutual Information (CMI) to track EEG changes during BB stimulations. EEG signals were acquired from 13 healthy subjects. Five-minute BBs with four different frequencies were tested: delta band (1 Hz), theta band (5 Hz), alpha band (10 Hz) and beta band (20 Hz). We observed RP increase in theta and alpha bands and decrease in beta band during delta and alpha BB stimulations. RP decreased in beta band during theta BB, while RP decreased in theta band during beta BB. However, no clear brainwave entrainment effect was identified. Connectivity changes were detected following the variation of RP during BB stimulations. Our observation supports the hypothesis that BBs could affect functional brain connectivity, suggesting that the mechanism of BB-brain interaction is worth further study.
authors.affiliation: School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Gao
authors.affiliation: Unit on Statistical Genomics, National Institute of Mental Health, NIH, Bethesda 20852, USA.
authors.forename: Hongbao
authors.initials: H
authors.lastname: Cao
authors.affiliation: School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Dong
authors.initials: D
authors.lastname: Ming
authors.affiliation: School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Qi
authors.affiliation: School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Xuemin
authors.initials: X
authors.lastname: Wang
authors.affiliation: School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Xiaolu
authors.initials: X
authors.lastname: Wang
authors.affiliation: School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China.
authors.forename: Runge
authors.initials: R
authors.lastname: Chen
authors.affiliation: School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, China. Electronic address: zpzpa@vip.sina.com.
authors.forename: Peng
authors.initials: P
authors.lastname: Zhou
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods*; D000328:Adult; D058256:Brain Waves / Q000502:physiology*; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D055815:Young Adult
keywords: Binaural beat; CMI; Connectivity; PLV; RP