title: Asthma, allergy and the risk of prostate cancer: results from the Montreal PROtEuS study.
abstract: BACKGROUND
  The few previous studies examining the association between asthma or allergy and prostate cancer (PCa) risk were inconclusive. This study aimed to evaluate these associations, and to explore in details the possible influence of current versus former allergic condition, age at onset, time since onset, and duration of each allergic condition.
  
  
  METHODS
  Detailed information on self-reported asthma and allergy was collected in the context of a large population-based case-control study conducted in Montreal, Canada. Study subjects included 1936 cases, diagnosed between 2005 and 2009, and 1995 population controls. Unconditional multivariate logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI) adjusting for age, ancestry and familial history of prostate cancer.
  
  
  RESULTS
  The ORs were 1.11 (95% CI: 0.89-1.40) and 0.98 (95% CI: 0.84-1.14) for ever reporting of asthma and allergy, respectively. These ORs did not substantially vary according to status (former or current), age at onset, time since onset, and duration of each allergic condition. PCa screening was not associated with allergic diseases reporting.
  
  
  CONCLUSIONS
  Overall, our findings are in line with the absence of an association between a history of asthma or allergy, and PCa risk.
authors.affiliation: Epidemiology and Biostatistics Unit, INRS-Institut Armand-Frappier, Université du Québec, Laval, Québec, Canada.
authors.forename: Deborah
authors.initials: D
authors.lastname: Weiss
authors.affiliation: Epidemiology and Biostatistics Unit, INRS-Institut Armand-Frappier, Université du Québec, Laval, Québec, Canada.
authors.forename: Mariam
authors.initials: M
authors.lastname: El-Zein
authors.affiliation: Epidemiology and Biostatistics Unit, INRS-Institut Armand-Frappier, Université du Québec, Laval, Québec, Canada; Department of Social and Preventive Medicine, Université de Montréal, Montréal, Québec, Canada; University of Montreal Hospital Research Centre (CRCHUM), Montréal, Québec, Canada.
authors.forename: Marie-Claude
authors.initials: MC
authors.lastname: Rousseau
authors.affiliation: Epidemiology and Biostatistics Unit, INRS-Institut Armand-Frappier, Université du Québec, Laval, Québec, Canada.
authors.forename: Hugues
authors.initials: H
authors.lastname: Richard
authors.affiliation: University of Montreal Hospital Research Centre (CRCHUM), Montréal, Québec, Canada.
authors.forename: Pierre I
authors.initials: PI
authors.lastname: Karakiewicz
authors.affiliation: Epidemiology and Biostatistics Unit, INRS-Institut Armand-Frappier, Université du Québec, Laval, Québec, Canada; Department of Social and Preventive Medicine, Université de Montréal, Montréal, Québec, Canada; University of Montreal Hospital Research Centre (CRCHUM), Montréal, Québec, Canada. Electronic address: marie-elise.parent@iaf.inrs.ca.
authors.forename: Marie-Élise
authors.initials: MÉ
authors.lastname: Parent
mesh_terms: D001249:Asthma / Q000453:epidemiology*; D002170:Canada; D016022:Case-Control Studies; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000453:epidemiology*; D012307:Risk Factors
keywords: Allergy; Asthma; Case–control study; Hay fever; Prostate cancer