title: Long-term longitudinal assessment of postoperative outcomes after congenital cataract surgery in children with congenital rubella syndrome.
abstract: OBJECTIVE
  To assess the intraoperative and long-term longitudinal postoperative outcomes of cataract surgery in children with congenital rubella syndrome.
  
  
  METHODS
  Iladevi Cataract & IOL Research Centre, Ahmedabad, India.
  
  
  METHODS
  Prospective observational clinical study.
  
  
  METHODS
  Children with congenital rubella syndrome who had cataract surgery were enrolled. All microphthalmic eyes were left aphakic. A 1-piece hydrophobic acrylic intraocular lens was implanted in the capsular bag in eyes without microphthalmos. The postoperative observations included complications and visual assessments up to 5 years.
  
  
  RESULTS
  The mean age of the 21 children (37 eyes) was 3.97 months ± 2.1 (SD). Intraocular lens implantation was performed in 12 eyes (32.4%), while 25 eyes (67.6%) were left aphakic. Postoperatively, the median follow-up was 60.79 months. Posterior synechiae were observed in 22 eyes (59.5%) and visual axis opacification in 9 eyes (24.3%). Secondary glaucoma was observed in 16 eyes (43.2%), of which 14 were aphakic and 1 was pseudophakic. Nine eyes required trabeculectomy. Age at surgery and ocular comorbidities were statistically significantly associated with secondary glaucoma (P<.05, χ(2) test and Kendall τB criteria P<.05). The mean corrected distance visual acuity at the final follow-up was 0.72 ± 0.56 logMAR.
  
  
  CONCLUSIONS
  The long-term results suggest good visual outcomes can be obtained with congenital cataract associated with congenital rubella syndrome after early surgical intervention. The rate of serious postoperative complications was acceptable.
authors.affiliation: From Raghudeep Eye Clinic (Shah, Praveen, A.R. Vasavada, V.A. Vasavada, Carelli, Rasoebala), Iladevi Cataract & IOL Research Center, Ahmedabad, India; Storm Eye Institute (Trivedi), Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Sajani K
authors.initials: SK
authors.lastname: Shah
authors.affiliation: From Raghudeep Eye Clinic (Shah, Praveen, A.R. Vasavada, V.A. Vasavada, Carelli, Rasoebala), Iladevi Cataract & IOL Research Center, Ahmedabad, India; Storm Eye Institute (Trivedi), Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Mamidipudi R
authors.initials: MR
authors.lastname: Praveen
authors.affiliation: From Raghudeep Eye Clinic (Shah, Praveen, A.R. Vasavada, V.A. Vasavada, Carelli, Rasoebala), Iladevi Cataract & IOL Research Center, Ahmedabad, India; Storm Eye Institute (Trivedi), Medical University of South Carolina, Charleston, South Carolina, USA. Electronic address: icirc@abhayvasavada.com.
authors.forename: Abhay R
authors.initials: AR
authors.lastname: Vasavada
authors.affiliation: From Raghudeep Eye Clinic (Shah, Praveen, A.R. Vasavada, V.A. Vasavada, Carelli, Rasoebala), Iladevi Cataract & IOL Research Center, Ahmedabad, India; Storm Eye Institute (Trivedi), Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Vaishali A
authors.initials: VA
authors.lastname: Vasavada
authors.affiliation: From Raghudeep Eye Clinic (Shah, Praveen, A.R. Vasavada, V.A. Vasavada, Carelli, Rasoebala), Iladevi Cataract & IOL Research Center, Ahmedabad, India; Storm Eye Institute (Trivedi), Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Roberta
authors.initials: R
authors.lastname: Carelli
authors.affiliation: From Raghudeep Eye Clinic (Shah, Praveen, A.R. Vasavada, V.A. Vasavada, Carelli, Rasoebala), Iladevi Cataract & IOL Research Center, Ahmedabad, India; Storm Eye Institute (Trivedi), Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Rupal H
authors.initials: RH
authors.lastname: Trivedi
authors.affiliation: From Raghudeep Eye Clinic (Shah, Praveen, A.R. Vasavada, V.A. Vasavada, Carelli, Rasoebala), Iladevi Cataract & IOL Research Center, Ahmedabad, India; Storm Eye Institute (Trivedi), Medical University of South Carolina, Charleston, South Carolina, USA.
authors.forename: Viktor
authors.initials: V
authors.lastname: Rasoebala
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D001036:Aphakia, Postcataract / Q000503:physiopathology*; D002386:Cataract / Q000151:congenital*; D002387:Cataract Extraction; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D007223:Infant; D007431:Intraoperative Complications; D019654:Lens Implantation, Intraocular; D008297:Male; D011183:Postoperative Complications; D011184:Postoperative Period; D011446:Prospective Studies; D019591:Pseudophakia / Q000503:physiopathology*; D012410:Rubella Syndrome, Congenital / Q000150:complications* / Q000175:diagnosis; D012412:Rubella virus / Q000276:immunology; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M