title: Corneal hysteresis, corneal resistance factor, and intraocular pressure measurements in eyes implanted with a small aperture corneal inlay.
abstract: OBJECTIVE
  To compare the postoperative corneal hysteresis (CH) and corneal resistance factor (CRF) of eyes implanted with a small aperture corneal inlay versus fellow eyes.
  
  
  METHODS
  Medical records of patients who underwent small aperture corneal inlay (KAMRA; AcuFocus, Inc., Irvine, CA) implantation were retrospectively reviewed. There were two groups: the implanted and non-implanted. Main outcome measures were CH, CRF, Goldmann-correlated intraocular pressure (IOPg), corneal-compensated IOP (IOPcc), and Goldmann applanation tonometry measurements performed preoperatively and at postoperative week 1 and months 1, 3, and 6.
  
  
  RESULTS
  The study included 68 eyes of 34 patients. CH was higher in the implanted group when compared with the non-implanted group at postoperative week 1 (12.2 ± 3.1 vs 10.9 ± 1.7 mm Hg; P = .007) and month 1 (12.3 ± 2.5 vs 10.9 ± 1.8 mm Hg; P = .001). CRF was higher in the implanted group when compared with the non-implanted group at postoperative week 1 (11.9 ± 2.9 vs 10.7 ± 1.6 mm Hg; P = .003) and month 1 (12.5 ± 2.5 vs 10.4 ± 1.8 mm Hg; P < .001). IOPcc was higher in the implanted group when compared with the non-implanted group at only the first postoperative month (17.1 ± 3.5 vs 14.3 ± 2.9 mm Hg; P < .001). There were no statistically significant differences in Goldmann applanation tonometry or IOPg measurements between the two groups (P > .05). At the 3-month postoperative visit, all parameters had returned to baseline and there was no change at the 6-month visit.
  
  
  CONCLUSIONS
  Implantation of the KAMRA corneal inlay does not induce a permanent change in CH or CRF. A transient increase in both was seen in the early postoperative period.
authors.forename: Alper
authors.initials: A
authors.lastname: Agca
authors.forename: Ahmet
authors.initials: A
authors.lastname: Demirok
authors.forename: Haci Ugur
authors.initials: HU
authors.lastname: Celik
authors.forename: Corina
authors.initials: C
authors.lastname: van de Pol
authors.forename: Kadir Ilker
authors.initials: KI
authors.lastname: Cankaya
authors.forename: Nimet Burcu
authors.initials: NB
authors.lastname: Celik
authors.forename: Dilek
authors.initials: D
authors.lastname: Yasa
authors.forename: Ihsan
authors.initials: I
authors.lastname: Yilmaz
authors.forename: Omer Faruk
authors.initials: OF
authors.lastname: Yilmaz
mesh_terms: D003315:Cornea / Q000502:physiology*; D003319:Corneal Stroma / Q000601:surgery*; D004548:Elasticity / Q000502:physiology*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011145:Polyvinyls; D011305:Presbyopia / Q000503:physiopathology / Q000601:surgery*; D019736:Prostheses and Implants; D019919:Prosthesis Implantation; D012189:Retrospective Studies; D014065:Tonometry, Ocular; D005465:Fluorocarbon Polymers
chemical_list: D011145:Polyvinyls; C024865:polyvinylidene fluoride; D005465:Fluorocarbon Polymers