title: The case of a new sequence type 7 serogroup X Neisseria meningitidis infection in China: may capsular switching change serogroup profile?
abstract: Neisseria meningitidis remains the leading cause of bacterial meningitis and septicemia worldwide. We describe a case of invasive meningococcal infection caused by serogroup X N. meningitidis with a unique sequence type (ST-7) in China. The strain may have arisen from locally prevalent hypervirulent serogroup A clones by capsular switching events.
authors.affiliation: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang Province 310051, China.
authors.forename: Jinren
authors.initials: J
authors.lastname: Pan
authors.affiliation: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang Province 310051, China.
authors.forename: Pingping
authors.initials: P
authors.lastname: Yao
authors.affiliation: Changsha Center for Disease Control and Prevention, Changsha, Hunan Province, China.
authors.forename: Heng
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang Province, China.
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Sun
authors.affiliation: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang Province 310051, China.
authors.forename: Hanqing
authors.initials: H
authors.lastname: He
authors.affiliation: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang Province 310051, China. Electronic address: shyxie@cdc.zj.cn.
authors.forename: Shuyun
authors.initials: S
authors.lastname: Xie
mesh_terms: D000328:Adult; D016667:Bacterial Capsules; D015373:Bacterial Typing Techniques; D002681:China; D005260:Female; D006801:Humans; D008589:Meningococcal Infections / Q000175:diagnosis / Q000382:microbiology*; D058885:Multilocus Sequence Typing; D009345:Neisseria meningitidis / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D065288:Serogroup; D055815:Young Adult
keywords: Multilocus sequence typing (MLST); Neisseria meningitidis; Serogroup X