title: Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency.
authors.affiliation: Department of Immunology and Microbiology, Autoimmune Genetics Laboratory, VIB and University of Leuven, Leuven, Belgium.
authors.forename: Lien
authors.initials: L
authors.lastname: Van Eyck
authors.affiliation: Duke University Medical Center, Durham, NC.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Hershfield
authors.affiliation: Department of Immunology and Microbiology, Autoimmune Genetics Laboratory, VIB and University of Leuven, Leuven, Belgium.
authors.forename: Diana
authors.initials: D
authors.lastname: Pombal
authors.affiliation: Duke University Medical Center, Durham, NC.
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Kelly
authors.affiliation: Duke University Medical Center, Durham, NC.
authors.forename: Nancy J
authors.initials: NJ
authors.lastname: Ganson
authors.affiliation: Department of Immunology and Microbiology, Experimental Laboratory Immunology, University of Leuven, Leuven, Belgium.
authors.forename: Leen
authors.initials: L
authors.lastname: Moens
authors.affiliation: Department of Immunology and Microbiology, Experimental Laboratory Immunology, University of Leuven, Leuven, Belgium.
authors.forename: Glynis
authors.initials: G
authors.lastname: Frans
authors.affiliation: Department of Immunology and Microbiology, Childhood Immunology, Department of Pediatrics, University Hospitals Leuven and University of Leuven, Leuven, Belgium.
authors.forename: Heidi
authors.initials: H
authors.lastname: Schaballie
authors.affiliation: Department of Pathology, University of Leuven, Leuven, Belgium.
authors.forename: Gert
authors.initials: G
authors.lastname: De Hertogh
authors.affiliation: Department of Immunology and Microbiology, Autoimmune Genetics Laboratory, VIB and University of Leuven, Leuven, Belgium.
authors.forename: James
authors.initials: J
authors.lastname: Dooley
authors.affiliation: Department of Immunology and Microbiology, Experimental Laboratory Immunology, University of Leuven, Leuven, Belgium.
authors.forename: Xavier
authors.initials: X
authors.lastname: Bossuyt
authors.affiliation: Department of Immunology and Microbiology, Childhood Immunology, Department of Pediatrics, University Hospitals Leuven and University of Leuven, Leuven, Belgium.
authors.forename: Carine
authors.initials: C
authors.lastname: Wouters
authors.affiliation: Department of Immunology and Microbiology, Autoimmune Genetics Laboratory, VIB and University of Leuven, Leuven, Belgium.
authors.forename: Adrian
authors.initials: A
authors.lastname: Liston
authors.affiliation: Department of Immunology and Microbiology, Childhood Immunology, Department of Pediatrics, University Hospitals Leuven and University of Leuven, Leuven, Belgium. Electronic address: Isabelle.Meyts@uzleuven.be.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Meyts
mesh_terms: D000243:Adenosine Deaminase / Q000097:blood / Q000172:deficiency* / Q000235:genetics / Q000276:immunology; D000361:Agammaglobulinemia / Q000097:blood / Q000235:genetics / Q000276:immunology / Q000628:therapy*; D002675:Child, Preschool; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007223:Infant; D036341:Intercellular Signaling Peptides and Proteins / Q000097:blood / Q000172:deficiency* / Q000235:genetics; D015850:Interleukin-6 / Q000097:blood; D018655:Lymphocyte Count; D008297:Male; D009154:Mutation; D010641:Phenotype; D016511:Severe Combined Immunodeficiency / Q000097:blood / Q000235:genetics / Q000276:immunology / Q000628:therapy*
chemical_list: C508600:IL6 protein, human; D036341:Intercellular Signaling Peptides and Proteins; D015850:Interleukin-6; C408373:ADA2 protein, human; D000243:Adenosine Deaminase