title: Primary prevention of anxiety disorders in primary care: A systematic review.
abstract: OBJECTIVE
  Anxiety disorders are the most prevalent psychiatric disorders in primary care and have significant social, economic, and interpersonal costs. Primary care is an ideal setting to prevent the appearance of anxiety disorders. The aim of this study was to evaluate the efficacy and cost-effectiveness of primary prevention interventions in anxiety disorders in the adult population receiving primary health care.
  
  
  METHODS
  A literature search was carried out in four databases-PubMed, PsycInfo, Cochrane, and Web of Science-from January 1980 to November 2013. Clinical trials and systematic reviews published in English and non-English languages and that evaluated the efficacy and/or cost-effectiveness of interventions of primary prevention for anxiety in primary care in the general adult population were included. Risk of bias was assessed by the Cochrane Risk Bias Tool and Overview Quality Assessment Questionnaire.
  
  
  RESULTS
  No high-quality research was identified that studied primary prevention of anxiety disorders in the adult population in the primary care setting. The few studies that exist focus on the child-adolescent population or on other types of interventions, usually as secondary prevention.
  
  
  CONCLUSIONS
  This study emphasizes the need for the development of high-quality clinical trials on the prevention of anxiety disorders in primary care.
authors.affiliation: Department of Psychiatry, Miguel Servet University Hospital, University of Zaragoza, REDIAPP, Isabel la Catolica, 1-3, 50009 Zaragoza, Spain. Electronic address: jgarcamp@gmail.com.
authors.forename: Javier
authors.initials: J
authors.lastname: García-Campayo
authors.affiliation: Department of Psychology & Sociology, University of Zaragoza, REDIAPP, Violante de Hungría, 23, 50009 Zaragoza, Spain.
authors.forename: Yolanda López
authors.initials: YL
authors.lastname: del Hoyo
authors.affiliation: Aragon Health Sciences Institute, San Juan Bosco, 13, 50009 Zaragoza, Spain.
authors.forename: Montserrat Salas
authors.initials: MS
authors.lastname: Valero
authors.affiliation: Aragon Health Sciences Institute, REDIAPP, CS. Arrabal, Andador Aragues Puerto, 2-4, 50015 Zaragoza, Spain.
authors.forename: Maria Cruz Pérez
authors.initials: MC
authors.lastname: Yus
authors.affiliation: 12 de Octubre Research Institute, Avda. de Córdoba, s/n, 28041 Madrid, Spain.
authors.forename: Eva Andrés
authors.initials: EA
authors.lastname: Esteban
authors.affiliation: REDIAPP, CS, Arrabal, Andador Aragues Puerto, 2-4, 50015 Zaragoza, Spain.
authors.forename: Marta Puebla
authors.initials: MP
authors.lastname: Guedea
authors.affiliation: Health Aragon, REDIAPP, CS, Arrabal, Andador Aragues Puerto, 2-4, 50015 Zaragoza, Spain.
authors.forename: Rosa Magallón
authors.initials: RM
authors.lastname: Botaya
mesh_terms: D001008:Anxiety Disorders / Q000517:prevention & control*; D006801:Humans; D008603:Mental Health; D011320:Primary Health Care; D011322:Primary Prevention / Q000191:economics / Q000379:methods*
keywords: Anxiety disorders; Primary health care; Primary prevention