title: Toward a prostate cancer precision medicine.
abstract: The promise of precision cancer medicine is that we will be able to pair clinical and genomic data to provide better and more efficient treatment for cancer care. Although the focus is on the optimal pairing of existing Food and Drug Administration-approved drugs with the patient׳s tumor, precision medicine should also help determine a patient׳s risk for disease progression. Precision medicine will hopefully also lead to improved molecular biomarkers. The specific needs for predictive biomarkers vary significantly based on cancer type. The chief aim for prostate cancer biomarker development is to help distinguish indolent from aggressive disease.
authors.affiliation: Institute for Precision Medicine of Weill Cornell Medical College and NewYork-Presbyterian Hospital, New York, NY; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY; Department of Urology, Weill Cornell Medical College, New York, NY; Meyer Cancer Center of Weill Cornell Medical College and NewYork-Presbyterian Hospital, New York, NY. Electronic address: rubinma@med.cornell.edu.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Rubin
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000235:genetics* / Q000628:therapy*
chemical_list: D014408:Biomarkers, Tumor
keywords: Biomarkers; Next generation sequencing; Precision medicine; Prostate cancer