title: In-syringe dispersive solid-phase extraction using dissolvable layered double oxide hollow spheres as sorbent followed by high-performance liquid chromatography for determination of 11 phenols in river water.
abstract: Layered double oxide hollow spheres (LDO-HSs) were synthesized and employed as a dissolvable sorbent in dispersive solid-phase extraction (DSPE) to extract eleven United States Environmental Protection Agency's priority phenols from aqueous samples. With their higher specific surface area, LDO-HSs showed much higher extraction efficiency than normal layered double hydroxides and layered double oxides. The entire extraction process was accomplished in a syringe. After DSPE, the sorbent with the analytes was isolated conveniently by directly expelling the spent sample solution out of the syringe. The analyte-enriched sorbent was then subsequently dissolved by withdrawing an acidic solution into the syringe. The final extract was analyzed by high-performance liquid chromatography with ultraviolet detection. The results showed that this method provided low limits of detection for the phenols (0.005-0.153 μg/L), good linearity (r(2)≥ 0.9956) and relative standard deviations of ≤ 6.7%. The optimized method was applied to water samples from 3 rivers. This simple extraction procedure was demonstrated to be a fast, efficient and convenient DSPE approach.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.
authors.forename: Sheng
authors.initials: S
authors.lastname: Tang
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.
authors.forename: Xuan Hao
authors.initials: XH
authors.lastname: Lin
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore; National University of Singapore Environmental Research Institute, T-Lab Building #02-01, 5A Engineering Drive 1, Singapore 117411, Singapore.
authors.forename: Sam Fong Yau
authors.initials: SF
authors.lastname: Li
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore; National University of Singapore Environmental Research Institute, T-Lab Building #02-01, 5A Engineering Drive 1, Singapore 117411, Singapore. Electronic address: chmleehk@nus.edu.sg.
authors.forename: Hian Kee
authors.initials: HK
authors.lastname: Lee
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D009930:Organic Chemicals; D010087:Oxides / Q000737:chemistry*; D010636:Phenols / Q000032:analysis* / Q000737:chemistry; D045483:Rivers / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation* / Q000379:methods; D012995:Solubility; D013594:Syringes; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000737:chemistry
chemical_list: D009930:Organic Chemicals; D010087:Oxides; D010636:Phenols; D014874:Water Pollutants, Chemical
keywords: Dispersive solid-phase extraction; Dissolvable sorbent; Layered double oxide hollow spheres; Phenols