title: Clinical outcome of pedestal cup endoprosthetic reconstruction after resection of a peri-acetabular tumour.
abstract: Peri-acetabular tumour resections and their subsequent reconstruction are among the most challenging procedures in orthopaedic oncology. Despite the fact that a number of different pelvic endoprostheses have been introduced, rates of complication remain high and long-term results are mostly lacking. In this retrospective study, we aimed to evaluate the outcome of reconstructing a peri-acetabular defect with a pedestal cup endoprosthesis after a type 2 or type 2/3 internal hemipelvectomy. A total of 19 patients (11M:8F) with a mean age of 48 years (14 to 72) were included, most of whom had been treated for a primary bone tumour (n = 16) between 2003 and 2009. After a mean follow-up of 39 months (28 days to 8.7 years) seven patients had died. After a mean follow-up of 7.9 years (4.3 to 10.5), 12 patients were alive, of whom 11 were disease-free. Complications occurred in 15 patients. Three had recurrent dislocations and three experienced aseptic loosening. There were no mechanical failures. Infection occurred in nine patients, six of whom required removal of the prosthesis. Two patients underwent hindquarter amputation for local recurrence. The implant survival rate at five years was 50% for all reasons, and 61% for non-oncological reasons. The mean Musculoskeletal Tumor Society score at final follow-up was 49% (13 to 87). Based on these poor results, we advise caution if using the pedestal cup for reconstruction of a peri-acetabular tumour resection.
authors.affiliation: Leiden University Medical Center, Department of Orthopaedic Surgery, Albinusdreef 2, 2300 RC Leiden, The Netherlands.
authors.forename: M P A
authors.initials: MP
authors.lastname: Bus
authors.affiliation: Leiden University Medical Center, Department of Orthopaedic Surgery, Albinusdreef 2, 2300 RC Leiden, The Netherlands.
authors.forename: E J
authors.initials: EJ
authors.lastname: Boerhout
authors.affiliation: Academic Medical Center, Department of Orthopaedic Surgery, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
authors.forename: J A M
authors.initials: JA
authors.lastname: Bramer
authors.affiliation: Leiden University Medical Center, Department of Orthopaedic Surgery, Albinusdreef 2, 2300 RC Leiden, The Netherlands.
authors.forename: P D S
authors.initials: PD
authors.lastname: Dijkstra
mesh_terms: D000077:Acetabulum; D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000601:surgery*; D002277:Carcinoma / Q000601:surgery; D005260:Female; D006428:Hemipelvectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010388:Pelvis; D011474:Prosthesis Design; D012189:Retrospective Studies; D012509:Sarcoma / Q000601:surgery; D016896:Treatment Outcome
keywords: Endoprosthesis; Pelvic; Peri-acetabular; Reconstruction