title: Using cost-effective intra-arterial chemotherapy to treat retinoblastoma in Chile.
abstract: Intra-arterial chemotherapy (IAC) has proved to be an effective treatment for retinoblastoma, but can be very expensive in developing countries. We report 2 patients from Chile in whom IAC resulted in globe salvation. Both patients had their medical care provided by the public health system and had failed standard therapy.
authors.affiliation: Ophthalmology Department, Hospital San Juan de Dios, Santiago, Chile; Ophthalmology Department, Clínica Alemana de Santiago, Facultad de Medicina Universidad del Desarrollo, Santiago, Chile.
authors.forename: Diego
authors.initials: D
authors.lastname: Ossandón
authors.affiliation: Ophthalmology Department, Clínica Alemana de Santiago, Facultad de Medicina Universidad del Desarrollo, Santiago, Chile. Electronic address: mario.zanolli@me.com.
authors.forename: Mario
authors.initials: M
authors.lastname: Zanolli
authors.affiliation: Pediatric Oncology Department, Hospital San Juan de Dios, Santiago, Chile; Pediatric Oncology Department, Clínica Alemana de Santiago, Facultad de Medicina Universidad del Desarrollo, Santiago, Chile.
authors.forename: Verónica
authors.initials: V
authors.lastname: Pérez
authors.affiliation: Interventional Neuroradiology Department, Clínica Alemana de Santiago, Facultad de Medicina Universidad del Desarrollo, Santiago, Chile.
authors.forename: Paulo
authors.initials: P
authors.lastname: Zúñiga
authors.affiliation: Interventional Neuroradiology Department, Clínica Alemana de Santiago, Facultad de Medicina Universidad del Desarrollo, Santiago, Chile.
authors.forename: Álvaro
authors.initials: Á
authors.lastname: Belmar
authors.affiliation: Pediatric Oncology Department, Hospital San Juan de Dios, Santiago, Chile; Pediatric Oncology Department, Clínica Alemana de Santiago, Facultad de Medicina Universidad del Desarrollo, Santiago, Chile.
authors.forename: Mónica
authors.initials: M
authors.lastname: Varas
authors.affiliation: Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
authors.forename: Carol L
authors.initials: CL
authors.lastname: Shields
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000191:economics* / Q000627:therapeutic use; D002677:Chile; D003362:Cost-Benefit Analysis; D003906:Developing Countries; D016527:Drug Costs; D006801:Humans; D007223:Infant; D007261:Infusions, Intra-Arterial / Q000191:economics*; D008297:Male; D008558:Melphalan / Q000008:administration & dosage; D019572:Retinal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D012175:Retinoblastoma / Q000188:drug therapy* / Q000473:pathology; D019772:Topotecan / Q000008:administration & dosage
chemical_list: D019772:Topotecan; D008558:Melphalan