title: Cyclin A2: a genuine cell cycle regulator?
abstract: Abstract Cyclin A2 belongs to the core cell cycle regulators and participates in the control of both S phase and mitosis. However, several observations suggest that it is also endowed with other functions, and our recent data shed light on its involvement in cytoskeleton dynamic and cell motility. From the transcription of its gene to its posttranslational modifications, cyclin A2 regulation reveals the complexity of the regulatory network shaping cell cycle progression. We summarize our current knowledge on this cell cycle regulator and discuss recent findings raising the possibility that cyclin A2 might play a much broader role in epithelial tissues homeostasis.
authors.forename: Nawal
authors.initials: N
authors.lastname: Bendris
authors.forename: Abdelhalim
authors.initials: A
authors.lastname: Loukil
authors.forename: Caroline
authors.initials: C
authors.lastname: Cheung
authors.forename: Nikola
authors.initials: N
authors.lastname: Arsic
authors.forename: Cosette
authors.initials: C
authors.lastname: Rebouissou
authors.forename: Robert
authors.initials: R
authors.lastname: Hipskind
authors.forename: Marion
authors.initials: M
authors.lastname: Peter
authors.forename: Bénédicte
authors.initials: B
authors.lastname: Lemmers
authors.forename: Jean Marie
authors.initials: JM
authors.lastname: Blanchard