title: [Characteristics of group A streptococcal meningitis in children].
abstract: Group A streptococcal (GAS) meningitis in children are rare. The aim of this study was to analyze the clinical, biological and outcome data on GAS meningitis recorded in the Bacterial Meningitis (BM) French Surveillance Network (GPIP/ACTIV). From 2001 through 2012, 4,564 children suffering from proven bacterial meningitis were recorded in the data base. Among them, 0.7 % were GAS infections. The median age was 5.6 years. A history of community acquired infection before the onset of GAS meningitis was frequent. Apart from the identification of the bacterial species, GAS meningitis were clinically and biologically indistinguishable from meningitis caused by other pathogens notably S. pneumoniae. Case fatality rate was 8 %.
authors.affiliation: Groupe de pathologie infectieuse pédiatrique (GPIP) de la Société française de pédiatrie, CHU Lenval, 57, avenue de la Californie, 06200 Nice, France; ACTIV (Association clinique et thérapeutique infantile du Val-de-Marne), 27, rue Inkermann, 94100 Saint-Maur-des-Fossés, France; Centre de recherche clinique (CRC) et Centre hospitalier intercommunal (CHI), 40, avenue de Verdun, 94010 Créteil, France. Electronic address: corinne.levy@activ-france.fr.
authors.forename: C
authors.initials: C
authors.lastname: Levy
authors.affiliation: Unité court séjour, petits nourrissons, service de néonatologie, CHI de Créteil, 40, avenue de Verdun, 94010 Créteil, France; Université Paris-Diderot, PRES Sorbonne-Paris-Cité, 46, rue Henri-Huchard, 75018 Paris, France.
authors.forename: Ph
authors.initials: P
authors.lastname: Bidet
authors.affiliation: Unité court séjour, petits nourrissons, service de néonatologie, CHI de Créteil, 40, avenue de Verdun, 94010 Créteil, France; Université Paris-Diderot, PRES Sorbonne-Paris-Cité, 46, rue Henri-Huchard, 75018 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Bonacorsi
authors.affiliation: ACTIV (Association clinique et thérapeutique infantile du Val-de-Marne), 27, rue Inkermann, 94100 Saint-Maur-des-Fossés, France.
authors.forename: S
authors.initials: S
authors.lastname: Béchet
authors.affiliation: Groupe de pathologie infectieuse pédiatrique (GPIP) de la Société française de pédiatrie, CHU Lenval, 57, avenue de la Californie, 06200 Nice, France; ACTIV (Association clinique et thérapeutique infantile du Val-de-Marne), 27, rue Inkermann, 94100 Saint-Maur-des-Fossés, France; Centre de recherche clinique (CRC) et Centre hospitalier intercommunal (CHI), 40, avenue de Verdun, 94010 Créteil, France; Service de microbiologie, hôpital Robert-Debré (AP-HP), 48, boulevard Sérurier, 75019 Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Cohen
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D005602:France / Q000453:epidemiology; D005838:Genotype; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D008297:Male; D016920:Meningitis, Bacterial / Q000453:epidemiology / Q000382:microbiology*; D012640:Seizures / Q000453:epidemiology; D012772:Shock, Septic / Q000453:epidemiology; D013290:Streptococcal Infections / Q000188:drug therapy / Q000453:epidemiology*; D013297:Streptococcus pyogenes / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents