title: Successful catheter-directed thrombolysis of a massive pulmonary embolism in a patient after recent pneumonectomy.
abstract: Massive pulmonary embolism (PE) after major thoracic surgery is an uncommon but life-threatening event that is challenging to manage. At present, the treatment of acute PE is either anticoagulation with or without systemic thrombolytic therapy. We report a case of a 65-year-old female with recent left pneumonectomy who developed a massive PE. The patient was successfully and safely treated with catheter-directed thrombolysis. To our knowledge, this is the first patient treated in this fashion.
authors.affiliation: Department of Radiology, Division of Interventional Radiology, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY.
authors.forename: Kyungmouk S
authors.initials: KS
authors.lastname: Lee
authors.affiliation: Department of Radiology, Division of Interventional Radiology, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY.
authors.forename: Akhilesh K
authors.initials: AK
authors.lastname: Sista
authors.affiliation: Department of Medicine, Division of Pulmonary & Critical Care Medicine, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY.
authors.forename: Oren A
authors.initials: OA
authors.lastname: Friedman
authors.affiliation: Department of Medicine, Division of Cardiology, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY.
authors.forename: James M
authors.initials: JM
authors.lastname: Horowitz
authors.affiliation: Department of Cardiothoracic Surgery, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY.
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Port
authors.affiliation: Department of Radiology, Division of Interventional Radiology, New York-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY. Electronic address: dcm9006@med.cornell.edu.
authors.forename: David C
authors.initials: DC
authors.lastname: Madoff
mesh_terms: D000368:Aged; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D011013:Pneumonectomy / Q000009:adverse effects*; D011655:Pulmonary Embolism / Q000188:drug therapy* / Q000209:etiology; D015912:Thrombolytic Therapy / Q000379:methods*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator
keywords: Catheter-directed; Pneumonectomy; Pulmonary embolism; Thrombolysis