title: Production of cis-11-eicosenoic acid by Mortierella fungi.
abstract: OBJECTIVE
  To find cis-11-eicosenoic acid (20:1ω9, EA)-producing micro-organisms.
  
  
  RESULTS
  We found EA-producing fungi by screening about 300 fungal strains and identified a major fatty acid accumulated in the Mortierella fungi as EA by means of GC-MS analysis. In particular, Mortierella chlamydospora CBS 529.75 produced a high amount of EA (36.3 mg g(-1) of dried cells) on cultivation at 28°C for 4 days and then at 12°C for 3 days. In the result of lipid analysis, most of the EA was a component of triacylglycerols, not phospholipids.
  
  
  CONCLUSIONS
  We found that M. chlamydospora CBS 529.75 was the best producer for the microbial production of EA.
  
  
  CONCLUSIONS
  EA is beneficial as a raw material for medical supplies and a moisturizing component of cosmetic creams. This is the first report of microbial production of EA.
authors.affiliation: Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kikukawa
authors.forename: E
authors.initials: E
authors.lastname: Sakuradani
authors.forename: Y
authors.initials: Y
authors.lastname: Nishibaba
authors.forename: T
authors.initials: T
authors.lastname: Okuda
authors.forename: A
authors.initials: A
authors.lastname: Ando
authors.forename: J
authors.initials: J
authors.lastname: Shima
authors.forename: S
authors.initials: S
authors.lastname: Shimizu
authors.forename: J
authors.initials: J
authors.lastname: Ogawa
mesh_terms: D005229:Fatty Acids, Monounsaturated / Q000032:analysis / Q000378:metabolism*; D008055:Lipids / Q000032:analysis; D020094:Mortierella / Q000737:chemistry / Q000378:metabolism*; D014280:Triglycerides / Q000737:chemistry
chemical_list: D005229:Fatty Acids, Monounsaturated; D008055:Lipids; D014280:Triglycerides; C572289:eicosenoic acid
keywords: Mortierella; eicosenoic acid; fatty acid elongase; polyunsaturated fatty acid; screening