title: Self-harm and suicidal behavior in borderline personality disorder with and without bulimia nervosa.
abstract: OBJECTIVE
  Few studies have investigated whether a diagnosis of Bulimia nervosa (BN) confers additional risk of life-threatening behaviors such as self-harm and suicidal behavior in borderline personality disorder (BPD).
  
  
  METHODS
  Participants were 483 treatment-seeking women diagnosed with BPD according to the Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II; First, Gibbon, Spitzer, Williams, & Benjamin, 1997; Diagnostic and Statistical Manual of Mental Disorders, 4th ed.; APA, 1994) and admitted to the Norwegian Network of Psychotherapeutic Day Hospitals between 1996 and 2009. Of these, 57 (11.8%) women met DSM-IV diagnostic criteria for BN according to the Mini-International Neuropsychiatric Interview (M.I.N.I.; Sheehan et al., 1998) and they were compared with women with BPD and other Axis I disorders.
  
  
  RESULTS
  We found that comorbid BN is uniquely and significantly associated with increased risk of suicidal behavior among women being treated for BPD. Findings underscore the importance of routinely screening for BN among women seeking treatment for BPD, as co-occurring bulimia appears to be a significant marker for immediate life-threatening behaviors in this already high-risk population, which is a significant public health issue. A significantly greater proportion of women with BPD-BN reported suicidal ideation at intake (past 7 days), engaged in self-harm behavior during treatment, and attempted suicide during treatment. All bivariate associations remained significant in the logistic regression models after controlling for mood, anxiety, and substance-related disorders.
  
  
  CONCLUSIONS
  The presence of a concurrent diagnosis of BN among women with BPD is significantly and uniquely associated with recent suicidal ideation, and self-harm behavior and suicide attempts during treatment after controlling for major classes of mental disorders. Co-occurring BN appears to represent a significant marker for immediate life-threatening behaviors in women seeking treatment for BPD. Extra vigilance and careful monitoring of suicidal behavior during treatment is important for these individuals, and routine screening for BN is warranted.
authors.affiliation: Department of Eating Disorders, Division of Mental Health and Addiction, Oslo University Hospital.
authors.forename: Deborah L
authors.initials: DL
authors.lastname: Reas
authors.affiliation: Department of Personality Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital.
authors.forename: Geir
authors.initials: G
authors.lastname: Pedersen
authors.affiliation: Institute for Clinical Medicine, Faculty of Medicine, University of Oslo.
authors.forename: Sigmund
authors.initials: S
authors.lastname: Karterud
authors.affiliation: Regional Department of Eating Disorders, Division of Mental Health and Addiction, Oslo University Hospital.
authors.forename: Øyvind
authors.initials: Ø
authors.lastname: Rø
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001883:Borderline Personality Disorder / Q000150:complications / Q000523:psychology*; D052018:Bulimia Nervosa / Q000150:complications / Q000523:psychology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D016728:Self-Injurious Behavior / Q000150:complications / Q000523:psychology*; D059020:Suicidal Ideation; D013406:Suicide, Attempted / Q000523:psychology*; D055815:Young Adult