title: Patching up broken hearts: cardiac cell therapy gets a bioengineered boost.
abstract: Preclinical and clinical studies for cardiac cell therapy have only seen moderate success due to poor engraftment and survival of transplanted cells. In this issue of Cell Stem Cell, Ye et al. (2014) employ a growth-factor-loaded fibrin patch and show improved cardiovascular cell survival after cell transplantation into a porcine model of ischemia reperfusion.
authors.affiliation: Stanford Cardiovascular Institute, Stanford, CA 94305, USA.
authors.forename: Vahid
authors.initials: V
authors.lastname: Serpooshan
authors.affiliation: Stanford Cardiovascular Institute, Stanford, CA 94305, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: smwu@stanford.edu.
authors.forename: Sean M
authors.initials: SM
authors.lastname: Wu
mesh_terms: D000818:Animals; D042783:Endothelial Cells / Q000637:transplantation*; D006352:Heart Ventricles / Q000378:metabolism*; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000502:physiology*; D009203:Myocardial Infarction / Q000628:therapy*; D009206:Myocardium / Q000378:metabolism*; D032383:Myocytes, Cardiac / Q000637:transplantation*; D032389:Myocytes, Smooth Muscle / Q000637:transplantation*; D033581:Stem Cell Transplantation