title: [Generation and application of dynamic standard reference intervals for analyzing results of comparative genomic hybridization].
abstract: The present work was aimed at generating the dynamic standard reference intervals (DSRI) and their application for chromosomal-aberration (CA) analysis. The evaluation of the generated DSRI was performed using the DNA samples from four patients with already known CA. High-resolution comparative genomic hybridization analysis (HR-CGH) allowed us to not only identify all of the CAs, that were not revealed by CGH, but also to detect the breakpoints and to determine the size of chromosomal imbalance.
authors.forename: M E
authors.initials: ME
authors.lastname: Min'zhenkova
authors.forename: N V
authors.initials: NV
authors.lastname: Shilova
authors.forename: Zh G
authors.initials: ZhG
authors.lastname: Markova
authors.forename: V G
authors.initials: VG
authors.lastname: Antonenko
authors.forename: I N
authors.initials: IN
authors.lastname: Lebedev
authors.forename: Iu O
authors.initials: IuO
authors.lastname: Kozlova
authors.forename: V V
authors.initials: VV
authors.lastname: Zemliakova
authors.forename: T V
authors.initials: TV
authors.lastname: Zolotukhina
mesh_terms: D002869:Chromosome Aberrations; D055028:Comparative Genomic Hybridization / Q000379:methods* / Q000592:standards*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D059785:Karyotype; D008297:Male; D012015:Reference Standards