title: Left Bundle Branch Block in Acute Cardiac Events: Insights From a 23-Year Registry.
abstract: Between 1991 and 2013, we evaluated the demographics, presentations, and final diagnosis of patients hospitalized with acute cardiac events and left bundle branch block (LBBB). Of 50 992 patients, 768 (1.5%) had LBBB. Compared with non-LBBB patients, patients with LBBB were mostly older, female, diabetic, and had hypertension and chronic kidney failure (CKF; P < .001 for all). Dyspnea (P < .001) and dizziness (P = .037) were more frequent in patients with LBBB. The most frequent cause of admission with LBBB was congestive heart failure (CHF; 54.2%), followed by ST-elevation myocardial infarction (STEMI; 13.3%), valvular heart disease (9.4%), unstable angina (8.3%) and Non-STEMI (7.7%). On multivariate analysis, CKF (odds ratio [OR]: 2.02, 95% confidence interval [CI]: 1.09-3.70) and LBBB (OR: 2.96, 95% CI: 2.01-4.42) were predictors of in-hospital mortality in the entire study population. Further analysis of patients with LBBB showed that CKF (OR: 2.93, 95% CI: 1.40-6.12) was the only predictor of in-hospital mortality. Regardless the presenting symptoms, CHF was the final diagnosis in most cases with LBBB.
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar.
authors.forename: Fahad
authors.initials: F
authors.lastname: Alkindi
authors.affiliation: Department of Clinical Medicine, Weill Cornell Medical School, Ar-Rayyan, Qatar Clinical Research, Trauma Section, Hamad Medical Corporation, Doha, Qatar Internal Medicine, Cardiology Section, Ahmed Maher Teaching Hospital, Cairo, Egypt.
authors.forename: Ayman
authors.initials: A
authors.lastname: El-Menyar
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar.
authors.forename: Jassim
authors.initials: J
authors.lastname: Al-Suwaidi
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar.
authors.forename: Ashfaq
authors.initials: A
authors.lastname: Patel
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar.
authors.forename: Abdurrazzak A
authors.initials: AA
authors.lastname: Gehani
authors.affiliation: Cardiovascular Research, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Rajvir
authors.initials: R
authors.lastname: Singh
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar.
authors.forename: Hajar
authors.initials: H
authors.lastname: Albinali
authors.affiliation: Department of Cardiology and Cardiovascular Surgery, Heart Hospital, HMC, Doha, Qatar abdarabi@yahoo.com.
authors.forename: Abdulrahman
authors.initials: A
authors.lastname: Arabi
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002037:Bundle-Branch Block / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D016009:Chi-Square Distribution; D015897:Comorbidity; D005260:Female; D006333:Heart Failure / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D016017:Odds Ratio; D011379:Prognosis; D011780:Qatar / Q000453:epidemiology; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D013997:Time Factors
keywords: Qatar; heart failure; left bundle branch block; myocardial infarction