title: Comparison of Nano-Sized Hydroxyapatite and β-Tricalcium Phosphate in the Treatment of Human Periodontal Intrabony Defects.
abstract: BACKGROUND
  Since the advent of nanotechnology, various materials have been introduced for the treatment of the bone defects which have shown promising results.
  
  
  OBJECTIVE
  The purpose of this study was to compare the effect of nano-sized Hydroxyapatite (NHA) and β-Tricalcium Phosphate (β-TCP) in the treatment of human periodontal defects.
  
  
  METHODS
  Tweleve patients with a total of 24 sites which were almost identical as determined clinically and radiographically were selected for the study. The selected sites were treated with access flap surgery were divided into two groups: Group I was treated with NHA and Group II treated with β-TCP. Following clinical and radiographic parameters were recorded at baseline, 3 months and 6 months post operatively: 1) Probing pocket depth (PPD); 2)Clinical attachment level (CAL); 3) Gingival recession (GR); 4) Radiographic Defect Depth.
  
  
  RESULTS
  Groups showed statistically significant improvements in soft and hard tissue parameters after 3 months and 6 months. Greater reduction in PPD, gain in CAL and Radiographic Defect Fill (RDF) was seen in Group I after three months whereas after six months were no statistically significant difference was seen with regard to soft and hard tissue measurements.
  
  
  CONCLUSIONS
  Within limits of the study, both NHA and β-TCP have proved to be beneficial in the management of periodontal defects. Treatment of intrabony periodontal defects with NHA leads to significant improvement in early clinical and radiographic outcomes as compared to β-TCP.
authors.affiliation: Senior Lecturer, Department of Periodontics, Desh Bhagat Dental College and Hospital , KK Road, Muktsar, Punjab, India .
authors.forename: Rohit
authors.initials: R
authors.lastname: Jain
authors.affiliation: Professor and Head, Department of Periodontics, Guru Nanak Dev Dental College and Research Institute , Patiala-Bathinda Highway, Sunam, Punjab, India .
authors.forename: Harjit
authors.initials: H
authors.lastname: Kaur
authors.affiliation: Professor-Department of Periodontics, Guru Nanak Dev Dental College and Research Institute , Patiala-Bathinda Highway, Sunam, Punjab, India .
authors.forename: Sanjiv
authors.initials: S
authors.lastname: Jain
authors.affiliation: Professor and Head, Department of Periodontics, Gian Sagar Dental College and Hospital , Patiala-Zirkpur Highway, Banur, Punjab, India .
authors.forename: Diljit
authors.initials: D
authors.lastname: Kapoor
authors.affiliation: Demonstrator, Department of Periodontics, Post Graduate Institute of Dental Sciences , Rohtak, Haryana, India .
authors.forename: Tarun
authors.initials: T
authors.lastname: Nanda
authors.affiliation: Lecturer, Department of Periodontics, Desh Bhagat Dental College and Hospital , KK Road, Muktsar, Punjab, India .
authors.forename: Megha
authors.initials: M
authors.lastname: Jain
keywords: Alloplasts; Bone grafts; Nano-hydroxyapatite; Tricalcium phosphate