title: Multicenter Study of Contraceptive Vaginal Ring (NuvaRing(®)) in Normal Daily Practice in Indian Women.
abstract: OBJECTIVE
  This was the first Indian multicenter study at six specialty hospitals, to assess the real-life usage of the vaginal ring in daily clinical practice.
  
  
  METHODS
  This open-label, prospective, single-arm, nonrandomized, interventional study enrolled 252 women aged >18 years, seeking contraception with no contraindications to the use of combined hormonal contraceptive. Women were provided the ring with a monthly follow-up schedule for three cycles. Cycle control, acceptability, tolerability, and safety assessments were recorded at each visit.
  
  
  RESULTS
  Regular menstrual bleeding was reported by 76.2 % (192/252) at baseline. In study completers, regular bleeding was seen in 94.1 % (192/204), 97.5 % (199/204), and 98 % (200/204) in the 1st, the 2nd, and the 3rd cycles, respectively. Most (94.2 % [195/207]) women were very satisfied or satisfied with the ring, and 93.2 % (193/207) would recommend it to others. No pregnancies or serious adverse events were reported.
  
  
  CONCLUSIONS
  The study demonstrated that NuvaRing(®) is a highly effective contraceptive method with an excellent cycle control. It is well tolerated and accepted by Indian women.
authors.affiliation: Gynecology and Obstetrics, Kokilaben Dhirubhai Ambani Hospital, Rao Saheb Achutrao Patwardhan Marg, Andheri (West), Mumbai, 400 053 India.
authors.forename: Suchitra N
authors.initials: SN
authors.lastname: Pandit
authors.affiliation: Gynecology and Obstetrics, Seth G. S. Medical College & KEM Hospital, A. Donde Marg, Parel, Mumbai, 400 012 India.
authors.forename: Anahita R
authors.initials: AR
authors.lastname: Chauhan
authors.affiliation: Department of Gynecology and Obstetrics, Yashoda Hospital, Raj Bhavan Road, Somajiguda, Hyderabad, 500 082 India.
authors.forename: Manjula
authors.initials: M
authors.lastname: Anagani
authors.affiliation: Department of Gynecology and Obstetrics, Sri Ramchandra Medical College & Research Institute, Sri Ramchandra University, No. 1 Ramchandra Marg, Porur, Chennai, 600 116 India.
authors.forename: Sanjeeva
authors.initials: S
authors.lastname: Reddy
authors.affiliation: Medical Affairs, Organon (India) Private Limited, A subsidiary of Merck & Co. Inc., Whitehouse Stationi, NJ, USA, Platina Building, 8th Floor, C-59, G-Block, Bandra Kurla Complex, Bandra (East), Mumbai, 400051 India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Birla
authors.affiliation: Medical Affairs, Organon (India) Private Limited, A subsidiary of Merck & Co. Inc., Whitehouse Stationi, NJ, USA, Platina Building, 8th Floor, C-59, G-Block, Bandra Kurla Complex, Bandra (East), Mumbai, 400051 India.
authors.forename: Subrat K
authors.initials: SK
authors.lastname: Ray
keywords: Acceptability; Contraceptive; Cycle control; Efficacy; NuvaRing®