title: Topographic wiring of the retinotectal connection in zebrafish.
abstract: The zebrafish retinotectal projection provides an attractive model system for studying many aspects of topographic map formation and maintenance. Visual connections initially start to form between 3 and 5 days postfertilization, and remain plastic throughout the life of the fish. Zebrafish are easily manipulated surgically, genetically, and chemically, and a variety of molecular tools exist to enable visualization and control of various aspects of map development. Here, we review zebrafish retinotectal map formation, focusing particularly on the detailed structure and dynamics of the connections, the molecules that are important in map creation, and how activity regulates the maintenance of the map.
authors.affiliation: Queensland Brain Institute, The University of Queensland, Brisbane QLD 4072, Australia.
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Kita
authors.affiliation: School of Biomedical Sciences, The University of Queensland, Brisbane QLD 4072, Australia.
authors.forename: Ethan K
authors.initials: EK
authors.lastname: Scott
authors.affiliation: Queensland Brain Institute, The University of Queensland, Brisbane QLD 4072, Australia.|School of Mathematics and Physics, The University of Queensland, Brisbane QLD 4072, Australia.
authors.forename: Geoffrey J
authors.initials: GJ
authors.lastname: Goodhill
mesh_terms: D000818:Animals; D012160:Retina / Q000502:physiology*; D013477:Superior Colliculi / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology*; D015027:Zebrafish / Q000033:anatomy & histology / Q000502:physiology
keywords: RGC; development; retinotectal map; tectum; zebrafish