title: The use of transcutaneous CO2 monitoring in cardiac arrest patients: a feasibility study.
abstract: BACKGROUND
  Prediction of the return of spontaneous circulation (ROSC) in cardiac arrest patients is a parameter for deciding when to stop cardiopulmonary resuscitation (CPR) or to start extracorporeal CPR. We investigated the change in transcutaneous PCO2 (PtcCO2) in cardiac arrest patients.
  
  
  METHODS
  This study was carried out as a retrospective chart review. Patients with out-of-hospital cardiac arrest or in-hospital cardiac arrest within the emergency department were included. PtcCO2 monitoring with a V-Sign™ combined monitor (SenTec Inc., Therwil, Switzerland) was applied to patients at the start of CPR. We divided the included patients into the ROSC group and the no ROSC group. The ROSC group was subdivided into those achieving ROSC <15 min CPR and >15 min CPR. The change in the PtcCO2 value was analyzed at 0 min, 5 min, 10 min, and 15 min from PtcCO2 stabilization and was compared among the groups.
  
  
  RESULTS
  A total of 42 patients were enrolled. Twenty-eight patients achieved ROSC; 13 patients achieved ROSC <15 min CPR and 15 patients achieved ROSC >15 min CPR. Fourteen patients expired without ROSC. The absolute values of PtcCO2 was lower in the ROSC group than in the no ROCS group. The PtcCO2 change over time had a tendency to decrease or to remain constant in the ROSC groups. In contrast, all patients in the no ROSC group experienced an increase in the PtcCO2 change during CPR except one case.
  
  
  CONCLUSIONS
  PtcCO2 monitoring provides non-invasive, continuous, and useful monitoring in cardiac arrest patients.
authors.forename: Sung-Hyuk
authors.initials: SH
authors.lastname: Choi
authors.forename: Jung-Youn
authors.initials: JY
authors.lastname: Kim
authors.affiliation: Department of Emergency Medicine, Korea University College of Medicine, 73, Inchon-ro, Sungbuk-gu, Seoul, South Korea. yyh71346@naver.com.
authors.forename: Young-Hoon
authors.initials: YH
authors.lastname: Yoon
authors.forename: Sung-Jun
authors.initials: SJ
authors.lastname: Park
authors.forename: Sung-Woo
authors.initials: SW
authors.lastname: Moon
authors.forename: Young-Duck
authors.initials: YD
authors.lastname: Cho
mesh_terms: D001785:Blood Gas Monitoring, Transcutaneous / Q000379:methods / Q000706:statistics & numerical data*; D002245:Carbon Dioxide / Q000097:blood*; D016887:Cardiopulmonary Resuscitation; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006323:Heart Arrest / Q000097:blood* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D020127:Recovery of Function; D015203:Reproducibility of Results; D012189:Retrospective Studies
chemical_list: D002245:Carbon Dioxide