title: [Study of membranotropic and antioxidant activity of flavonoids and their complexes with ferric iron].
abstract: We studied the interaction with liposomes and the antioxidant activity of flavonoid (quercetin, catechin, taxifolin) complexes with iron (III). It was found that the lipophilicity of complexes depends on an iron:flavonoid ratio and grows at a ratio of 1 to 1, while complexes in a 2:1 ratio were the most effective to slow down the lipid peroxidation and restore radical 2,2-diphenyl-1-pic: rylhydrazyl. Thus, the stoichiometry of complexes formed in aqueous solution, may differ from the stoichiometry of complexes that most effectively protect membranes from.peroxidation.
authors.forename: E A
authors.initials: EA
authors.lastname: Iagol'nik
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Tarakhovskiĭ
authors.forename: I B
authors.initials: IB
authors.lastname: Klenina
authors.forename: S M
authors.initials: SM
authors.lastname: Kuznetsova
authors.forename: E N
authors.initials: EN
authors.lastname: Muzafarov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Kim
mesh_terms: D000975:Antioxidants / Q000737:chemistry; D001713:Biphenyl Compounds / Q000737:chemistry; D002392:Catechin / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D015227:Lipid Peroxidation; D008081:Liposomes / Q000737:chemistry*; D010084:Oxidation-Reduction; D010851:Picrates / Q000737:chemistry
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D005419:Flavonoids; D008081:Liposomes; D010851:Picrates; D002392:Catechin; C004931:1,1-diphenyl-2-picrylhydrazyl; D007501:Iron