title: Two cases of rupture of esophagogastric varices during the course of oxaliplatin-based chemotherapy for colorectal cancer.
abstract: Some cases of portal hypertension developing during the course of oxaliplatin-based chemotherapy have been reported. However, there have been no reports of rupture of esophagogastric varices (EGV) in Japan. We present two cases of rupture of EGV during the course of oxaliplatin-based chemotherapy. One case was treated via balloon-occluded retrograde transvenous obliteration, and the other case was treated by using endoscopic variceal ligation and endoscopic injection sclerotherapy. On the basis of our results, we recommend careful monitoring for the occurrence of EGV during the course of oxaliplatin-based chemotherapy.
authors.affiliation: Department of Gastroenterology and Hepatology, St. Marianna University School of Medicine.
authors.forename: Ryuta
authors.initials: R
authors.lastname: Shigefuku
authors.forename: Hideaki
authors.initials: H
authors.lastname: Takahashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Tsuda
authors.forename: Hiroki
authors.initials: H
authors.lastname: Ikeda
authors.forename: Kotaro
authors.initials: K
authors.lastname: Matsunaga
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Matsumoto
authors.forename: Chiaki
authors.initials: C
authors.lastname: Okuse
authors.forename: Narikazu
authors.initials: N
authors.lastname: Boku
authors.forename: Fumio
authors.initials: F
authors.lastname: Itoh
authors.forename: Michihiro
authors.initials: M
authors.lastname: Suzuki
mesh_terms: D000368:Aged; D017542:Aneurysm, Ruptured / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004932:Esophageal and Gastric Varices / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000009:adverse effects* / Q000627:therapeutic use; D000077150:Oxaliplatin; D012004:Rectal Neoplasms / Q000188:drug therapy; D012811:Sigmoid Neoplasms / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; D000077150:Oxaliplatin