title: Ecthyma gangrenosum skin lesions in previously healthy children.
abstract: Ecthyma gangrenosum (EG) is an uncommon skin lesion that usually develops in patients with known immune deficiency or who are on immunosuppressive treatment. We report on five previously healthy children presenting with EG. Three of them developed severe neutropaenia. Immunologic work-up revealed chronic neutropaenia in two.
  
  
  CONCLUSIONS
  Recognition of EG is essential for providing early appropriate empiric antibiotic treatment. An immunologic work-up should be done, although a concomitant viral infection can be the predisposing factor.
authors.affiliation: Department of Pediatrics, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Neta
authors.initials: N
authors.lastname: Cohen
authors.forename: Tali
authors.initials: T
authors.lastname: Capua
authors.forename: Efraim
authors.initials: E
authors.lastname: Bilavsky
authors.forename: Hila
authors.initials: H
authors.lastname: Dias-Polak
authors.forename: Dror
authors.initials: D
authors.lastname: Levin
authors.forename: Galia
authors.initials: G
authors.lastname: Grisaru-Soen
mesh_terms: D004473:Ecthyma / Q000175:diagnosis* / Q000276:immunology / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009503:Neutropenia / Q000150:complications / Q000175:diagnosis; D011552:Pseudomonas Infections / Q000175:diagnosis* / Q000276:immunology; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*
keywords: Ecthyma gangrenosum; Healthy children; Pseudomonas aeruginosa; Skin lesions