title: Recent progress in the field of glycoconjugates.
abstract: The ubiquity of glycoconjugates in nature and their role in different biological processes, has led to the development of several methodologies to synthesize these molecules. Synthetic glycoconjugates are now used to answer a variety of glycoconjugate-related biological questions and have provided new potential vaccines against cancer, viral, and bacterial infections and new biotechnological tools. This review aims to collect and compile the recent advances in the field of glycopeptides, glycoproteins, and glycolipid synthesis and also to update the previous reviews made on this subject. Finally, by highlighting the successes and failures of past research, we hope that this review will inspire fruitful research in this important medicinal chemistry field.
authors.affiliation: REQUIMTE, CQFB, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal. Electronic address: cic17468@campus.fct.unl.pt.
authors.forename: Carina I C
authors.initials: CI
authors.lastname: Crucho
authors.affiliation: Instituto Superior de Ciências da Saúde Egas Moniz, 2829-511 Caparica, Portugal.
authors.forename: Paula
authors.initials: P
authors.lastname: Correia-da-Silva
authors.affiliation: REQUIMTE, CQFB, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal.
authors.forename: Krasimira T
authors.initials: KT
authors.lastname: Petrova
authors.affiliation: REQUIMTE, CQFB, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal. Electronic address: mtb@fct.unl.pt.
authors.forename: M Teresa
authors.initials: MT
authors.lastname: Barros
mesh_terms: D060326:Chemistry Techniques, Synthetic; D002626:Chemistry, Pharmaceutical; D006001:Glycoconjugates / Q000138:chemical synthesis / Q000737:chemistry; D006017:Glycolipids / Q000138:chemical synthesis / Q000737:chemistry; D006020:Glycopeptides / Q000138:chemical synthesis / Q000737:chemistry; D006023:Glycoproteins / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D006001:Glycoconjugates; D006017:Glycolipids; D006020:Glycopeptides; D006023:Glycoproteins
keywords: Carbohydrates; Glycobiology; Glycoconjugates