title: [Non-invasive transcutaneous spinal cord stimulation facilitates locomotor activity in decerebrated and spinal cats].
abstract: It is known that spinal neuronal networks activated by epidural electrical stimulation (EES) can produce the stepping EMG pattern and control the locomotor behavior. At present study we showed that non-invasive transcutaneous electrical spinal cord stimulation (tESCS) applied to the lumbar-sacral enlargement can facilitate the locomotor activity in decerebrated and spinal animals. The comparison of the motor responses evoked by EES vs tESCS showed that both methods produce the locomotor patterns with close properties and similar reflex mechanisms. The data obtained suggest that tESCS is an efficient approach for investigation of the locomotor control in acute and chronic experiments as well as facilitates of the locomotor abilities after spinal cord injury. Taking to account the non-invasivity and easement of tESCS, this approach could be further implemented in clinical practice for rehabilitation of the patient with spinal cord injury.
authors.forename: P E
authors.initials: PE
authors.lastname: Musienko
authors.forename: I N
authors.initials: IN
authors.lastname: Bogacheva
authors.forename: A A
authors.initials: AA
authors.lastname: Savochin
authors.forename: V A
authors.initials: VA
authors.lastname: Kilimnik
authors.forename: O V
authors.initials: OV
authors.lastname: Gorskiĭ
authors.forename: O A
authors.initials: OA
authors.lastname: Nikitin
authors.forename: Ia P
authors.initials: IaP
authors.lastname: Gerasimenko
mesh_terms: D000818:Animals; D002415:Cats; D003655:Decerebrate State / Q000503:physiopathology / Q000628:therapy; D004558:Electric Stimulation; D004576:Electromyography; D009043:Motor Activity / Q000502:physiology*; D013116:Spinal Cord / Q000503:physiopathology / Q000528:radiation effects; D013119:Spinal Cord Injuries / Q000503:physiopathology / Q000628:therapy*; D062187:Spinal Cord Stimulation; D013127:Spinal Nerves / Q000503:physiopathology* / Q000528:radiation effects