title: Latent class analysis of discordance between results of drug use assessments in the CATIE data.
abstract: OBJECTIVE
  The primary aim is to examine concordant/discordant results of drug use assessments in adults with schizophrenia.
  
  
  METHODS
  Latent class analysis and multinomial logistic regression were used to examine concordance/discordance between drug use measures and identify characteristics differentiating participants across classes.
  
  
  RESULTS
  Four classes - non-users, users, probable users, and RIA discordant - fit best. Age, sex, race/ethnicity, and psychiatric symptoms differed significantly across classes.
  
  
  CONCLUSIONS
  Findings showed that discordance between results occurs at non-trivial rates and is, in part, attributable to individual characteristics. Results suggest the need for strategies to limit discordance and improve detection of drug use in adults with schizophrenia.
authors.affiliation: Department of Psychology, North Carolina State University, Campus Box 7650, Raleigh, NC 27695, United States. Electronic address: kljeske@ncsu.edu.
authors.forename: Kiersten L
authors.initials: KL
authors.lastname: Johnson
authors.affiliation: Department of Psychology, North Carolina State University, Campus Box 7650, Raleigh, NC 27695, United States. Electronic address: sdesmarais@ncsu.edu.
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Desmarais
authors.affiliation: Department of Psychiatry & Behavioral Sciences, Duke University Medical Center, 238 Civitan Building, Box 3173, Durham, NC 27710, United States. Electronic address: marvin.swartz@duke.edu.
authors.forename: Marvin S
authors.initials: MS
authors.lastname: Swartz
authors.affiliation: Behavioral Health Epidemiology Program, RTI International, 3040 E. Cornwallis Road, P.O. Box 12194, Research Triangle Park, NC 27709, United States. Electronic address: rvandorn@rti.org.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Van Dorn
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D003627:Data Interpretation, Statistical; D005260:Female; D006197:Hair / Q000737:chemistry; D006801:Humans; D016015:Logistic Models; D008297:Male; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D057566:Self Report; D019966:Substance-Related Disorders / Q000150:complications* / Q000175:diagnosis* / Q000453:epidemiology; D016482:Urinalysis
chemical_list: D014150:Antipsychotic Agents
keywords: Assessment; Drug use; Latent class analysis; Schizophrenia