title: A highly selective and sensitive probe for Cu2+ based on rhodamine-pyridazine conjugate and its application.
abstract: A naked-eye fluorescent chemodosimeter based on rhodamine-pyridazine conjugate L was synthesized and characterized. L exhibited high selectivity and excellent sensitivity in both absorbance and fluorescence detection of Cu(2+) in aqueous solution with a broad pH span (1-10). The detection limit of the probe was shown to be up to 0.336 ppm. A simple paper test-strip system for the rapid monitoring of Cu(2+) was developed, indicating its convenient use in environmental samples. Furthermore, fluorescence imaging experiments of Cu(2+) in living MGC803 cells demonstrated its value of practical applications in biological systems.
authors.affiliation: Phosphorus Chemical Engineering Research Center of Henan Province, The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, China.
authors.forename: Peigang
authors.initials: P
authors.lastname: Ding
authors.forename: Shao
authors.initials: S
authors.lastname: Li
authors.forename: Linchao
authors.initials: L
authors.lastname: Yang
authors.forename: Junye
authors.initials: J
authors.lastname: Cheng
authors.forename: Zhenji
authors.initials: Z
authors.lastname: Wang
authors.forename: Yufen
authors.initials: Y
authors.lastname: Zhao
authors.forename: Yong
authors.initials: Y
authors.lastname: Ye
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival; D003300:Copper / Q000032:analysis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D011724:Pyridazines / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D011724:Pyridazines; D012235:Rhodamines; C062482:pyridazine; D003300:Copper