title: DNA-templated silver nanoclusters for multiplexed fluorescent DNA detection.
abstract: Novel label-free/conjugation-free molecular beacons are designed based on DNA templated-silver nanoclusters for multiplexed DNA detection. The assay is implemented in solution, which makes it easy for the in-situ and real-time analysis. This study demonstrates a new method for multiplexd detection of biological molecules by using fluorescent Ag nanocluster-based molecular beacon probes.
authors.affiliation: Key Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials, National Jiangsu Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, Nanjing, 210023, P. R. China; School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798, Singapore.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.forename: Changfeng
authors.initials: C
authors.lastname: Zhu
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Chaoliang
authors.initials: C
authors.lastname: Tan
authors.forename: Jian
authors.initials: J
authors.lastname: Yang
authors.forename: Bo
authors.initials: B
authors.lastname: Chen
authors.forename: Lianhui
authors.initials: L
authors.lastname: Wang
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000032:analysis / Q000737:chemistry* / Q000235:genetics*; D017404:In Situ Hybridization, Fluorescence / Q000379:methods*; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D054802:Molecular Imprinting / Q000379:methods*; D008969:Molecular Sequence Data; D053761:Nanocomposites / Q000737:chemistry / Q000648:ultrastructure; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012834:Silver / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D012834:Silver; D004247:DNA
keywords: DNA; fluorescence; multiplexed detection; sensors; silver nanoclusters