title: [The new classification of breast cancers: finding the luminal A].
abstract: OBJECTIVE
  To compare the distributions of patients with clinical-pathological subtypes of luminal B-like breast cancer according to the 2011 and 2013 St. Gallen International Breast Cancer Conference Expert Panel.
  
  
  METHODS
  We studied 142 women with breast cancer who were positive to estrogen receptor and had been treated in São Paulo state, southeast Brazil. The expression of the following receptors was assessed by immunohistochemistry: estrogen, progesterone (PR) and Ki-67. The expression of HER-2 was measured by fluorescent in situ hybridization analysis in tissue microarray.
  
  
  RESULTS
  There were 29 cases of luminal A breast cancers according to the 2011 St. Gallen International Breast Cancer Conference Expert Panel that were classified as luminal B-like in the 2013 version. Among the 65 luminal B-like breast cancer cases, 29 (45%) were previous luminal A tumors, 15 cases (20%) had a Ki-67 >14% and were at least 20% PR positive and 21 cases (35%) had Ki-67 >14% and more than 20% were PR positive.
  
  
  CONCLUSIONS
  The 2013 St. Gallen consensus updated the definition of intrinsic molecular subtypes and increased the number of patients classified as having luminal B-like breast cancer in our series, for whom the use of cytotoxic drugs will probably be proposed with additional treatment cost.
authors.affiliation: Departamento de Ginecologia e Obstetrícia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP, Campinas, SP, Brasil.
authors.forename: Katia Piton
authors.initials: KP
authors.lastname: Serra
authors.affiliation: Departmento de Anatomia Patológica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP, Campinas, SP, Brasil.
authors.forename: Susana
authors.initials: S
authors.lastname: Ramalho
authors.affiliation: Departamento de Ginecologia e Obstetrícia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP, Campinas, SP, Brasil.
authors.forename: Renato
authors.initials: R
authors.lastname: Torresan
authors.affiliation: Departmento de Anatomia Patológica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP, Campinas, SP, Brasil.
authors.forename: Jose
authors.initials: J
authors.lastname: Vassallo
authors.affiliation: Departamento de Ginecologia e Obstetrícia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP, Campinas, SP, Brasil.
authors.forename: Luis Otávio Zanatta
authors.initials: LO
authors.lastname: Sarian
authors.affiliation: Departmento de Anatomia Patológica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP, Campinas, SP, Brasil.
authors.forename: Geisilene Russano de Paiva
authors.initials: GR
authors.lastname: Silva
authors.affiliation: Departamento de Ginecologia e Obstetrícia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP, Campinas, SP, Brasil.
authors.forename: Sophie
authors.initials: S
authors.lastname: Derchain
mesh_terms: D001943:Breast Neoplasms / Q000145:classification* / Q000473:pathology*; D015331:Cohort Studies; D005260:Female; D006801:Humans