title: Uptake during an oral cholera vaccine pilot demonstration program, Odisha, India.
abstract: Approximately 30% of reported global cholera cases occur in India. In 2011, a household survey was conducted 4 months after an oral cholera vaccine pilot demonstration project in Odisha India to assess factors associated with vaccine up-take and exposure to a communication and social mobilization campaign. Nine villages were purposefully selected based on socio-demographics and demonstration participation rates. Households were stratified by level of participation and randomly selected. Bivariate and ordered logistic regression analyses were conducted. 517/600 (86%) selected households were surveyed. At the household level, participant compared to non-participant households were more likely to use the local primary health centers for general healthcare (P < 0.001). Similarly, at the village level, higher participation was associated with use of the primary health centers (P < 0.001) and private clinics (p = 0.032). Also at the village level, lower participation was associated with greater perceived availability of effective treatment for cholera (p = 0.013) and higher participation was associated with respondents reporting spouse as the sole decision-maker for household participation in the study. In terms of pre-vaccination communication, at the household level verbal communication was reported to be more useful than written communication. However written communication was perceived to be more useful by respondents in low-participating villages compared to average-participating villages (p = 0.007) These data on participation in an oral cholera vaccine demonstration program are important in light of the World Health Organization's (WHO) recommendations for pre-emptive use of cholera vaccine among vulnerable populations in endemic settings. Continued research is needed to further delineate barriers to vaccine up-take within and across targeted communities in low- and middle-income countries.
authors.affiliation: a Regional Medical Research Center (RMRC) ; Bhubaneswar , India.
authors.forename: Shantanu K
authors.initials: SK
authors.lastname: Kar
authors.forename: Alfred
authors.initials: A
authors.lastname: Pach
authors.forename: Binod
authors.initials: B
authors.lastname: Sah
authors.forename: Anna S
authors.initials: AS
authors.lastname: Kerketta
authors.forename: Bikash
authors.initials: B
authors.lastname: Patnaik
authors.forename: VijayaLaxmi
authors.initials: V
authors.lastname: Mogasale
authors.forename: Yang Hee
authors.initials: YH
authors.lastname: Kim
authors.forename: Shyam Bandhu
authors.initials: SB
authors.lastname: Rath
authors.forename: Sunheang
authors.initials: S
authors.lastname: Shin
authors.forename: Hemant K
authors.initials: HK
authors.lastname: Khuntia
authors.forename: Anuj
authors.initials: A
authors.lastname: Bhattachan
authors.forename: Mahesh K
authors.initials: MK
authors.lastname: Puri
authors.forename: Thomas F
authors.initials: TF
authors.lastname: Wierzba
authors.forename: Linda M
authors.initials: LM
authors.lastname: Kaljee
mesh_terms: D000284:Administration, Oral; D002771:Cholera / Q000276:immunology / Q000517:prevention & control*; D022121:Cholera Vaccines / Q000008:administration & dosage / Q000627:therapeutic use*; D003142:Communication; D003256:Community Participation; D003657:Decision Making; D003695:Delivery of Health Care / Q000706:statistics & numerical data*; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007194:India; D010342:Patient Acceptance of Health Care; D010865:Pilot Projects; D014611:Vaccination; D035862:Vulnerable Populations; D014944:World Health Organization
chemical_list: D022121:Cholera Vaccines
keywords: Bhubaneswar India; WHO; DHS; Directorate of Health Services; India; International Vaccine Institute; PHC; Odisha India; ORC; Oral Cholera Vaccine; IVI; Primary Health Centers; RMRC; Regional Medical Research Center; World Health Organization; cholera; communication campaigns; social-behavioral research; vaccine up-take