title: Gastric large cell neuroendocrine carcinoma with venous tumor thrombus: the value of PET/CT and contrast-enhanced computed tomography.
abstract: Venous involvement is commonly detected microscopically on gastric neuroendocrine carcinomas (NECs), but related imaging studies have been rarely documented. We report a rare case of gastric large cell NEC with tumor thrombi in gastric and splenic veins, elevated serum alpha fetoprotein, and multiple hepatic nodules. In this case, (18)F-fluorodeoxyglucose positron emission tomography combined with contrast-enhanced computed tomography provided valuable information on tumor staging.
authors.affiliation: Department of Nuclear Medicine, Peking University Third Hospital, Beijing, China. Electronic address: songle1983@qq.com.
authors.forename: Le
authors.initials: L
authors.lastname: Song
authors.affiliation: Department of Gastroenterology, Peking University Third Hospital, Beijing, China.
authors.forename: Zhu
authors.initials: Z
authors.lastname: Jin
authors.affiliation: Department of Nuclear Medicine, Peking University Third Hospital, Beijing, China.
authors.forename: Weifang
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Nuclear Medicine, Peking University Third Hospital, Beijing, China.
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D018278:Carcinoma, Neuroendocrine / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods; D010690:Phlebography; D049268:Positron-Emission Tomography; D013162:Splenic Vein / Q000000981:diagnostic imaging; D013270:Stomach / Q000098:blood supply; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology; D013927:Thrombosis / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D014680:Veins / Q000000981:diagnostic imaging; D020246:Venous Thrombosis / Q000175:diagnosis*
chemical_list: D019788:Fluorodeoxyglucose F18
keywords: CT; Gastric neuroendocrine carcinoma; Liver metastasis; PET; Tumor thrombus