title: Aspartame-stabilized gold-silver bimetallic biocompatible nanostructures with plasmonic photothermal properties, antibacterial activity, and long-term stability.
abstract: Gold-silver core-shell nanoparticles stabilized with a common sweetener, aspartame (AuNP@Ag@Asm), combine the antimicrobial properties of silver with the photoinduced plasmon-mediated photothermal effects of gold. The particles were tested with several bacterial strains, while biocompatibility was verified with human dermal fibroblasts.
authors.affiliation: Department of Chemistry and Centre for Catalysis Research and Innovation, University of Ottawa , Ottawa, Ontario K1N 6N5, Canada.
authors.forename: Chiara
authors.initials: C
authors.lastname: Fasciani
authors.forename: M Jazmin
authors.initials: MJ
authors.lastname: Silvero
authors.forename: Maria Alexandra
authors.initials: MA
authors.lastname: Anghel
authors.forename: Gerardo A
authors.initials: GA
authors.lastname: Argüello
authors.forename: Maria Cecilia
authors.initials: MC
authors.lastname: Becerra
authors.forename: Juan C
authors.initials: JC
authors.lastname: Scaiano
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001218:Aspartame / Q000737:chemistry* / Q000494:pharmacology; D004355:Drug Stability; D005347:Fibroblasts / Q000187:drug effects; D006046:Gold / Q000737:chemistry*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D046529:Microscopy, Electron, Transmission; D015394:Molecular Structure; D012834:Silver / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects*; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D012834:Silver; D006046:Gold; D001218:Aspartame