title: Management of microanastomosis in patients affected by vessel diseases.
abstract: OBJECTIVE
  In the last 10 years with the advances in microsurgery of techniques and materials the indications for free tissue transfer have considerably been increased. But, there are still some limitations and drawbacks. Among risk factors associated with flap failure, atherosclerosis can affect both the flap and the recipient vessels of free microvascular tissue transfers. The purpose of this paper is to discuss about the pathogenesis of Monckeberg's sclerosis, and the topics that must be taken into consideration when performing microsurgery in these patients.
  
  
  METHODS
  PubMed database was searched using Mesh. The following terms was added to the search builder: Monckeberg's sclerosis, free flap. The Boolean operator "AND" was selected. All the selectable Mesh headings for "Monckeberg's sclerosis" and "free flap" were included.
  
  
  RESULTS
  Almost all the literature works about microsurgery in Monckeberg's sclerosis patient show the importance of an accurate preoperative and postoperative evaluation and of a proper surgical technique.
  
  
  CONCLUSIONS
  When adequate preoperative evaluation, surgical technique and postoperative monitoring are performed, even severe atherosclerosis should not be considered an absolute contraindication for microvascular surgery.
authors.affiliation: Department of Surgery "P. Valdoni", U.O. of Plastic Reconstructive and Aesthetic Surgery, "Sapienza" University of Rome, Rome, Italy. federicolotorto@gmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Cigna
authors.forename: F
authors.initials: F
authors.lastname: Lo Torto
authors.forename: P
authors.initials: P
authors.lastname: Parisi
authors.forename: A
authors.initials: A
authors.lastname: Felli
authors.forename: D
authors.initials: D
authors.lastname: Ribuffo
mesh_terms: D001163:Arteriovenous Anastomosis / Q000473:pathology* / Q000601:surgery*; D050197:Atherosclerosis / Q000175:diagnosis* / Q000601:surgery*; D019468:Disease Management; D006801:Humans; D008866:Microsurgery / Q000379:methods* / Q000639:trends; D050380:Monckeberg Medial Calcific Sclerosis / Q000175:diagnosis / Q000601:surgery; D013524:Surgical Flaps / Q000639:trends