title: Almagate interference in breath test results for the diagnosis of Helicobacter pylori infection.
abstract: BACKGROUND
  Infection by Helicobacter pylori is common and affects both genders at any age. The 13C-urea breath test is a widely used test for the diagnosis of this infection. However, multiple drugs used for the treatment of Helicobacter pylori infection symptoms have interactions with this breath test that generate false negative results. This observational study was to assess the potential interaction between almagate and the breath test.
  
  
  METHODS
  Thirty subjects on almagate therapy who underwent a breath test were included. If the result was negative, almagate was withdrawn for a month and the breath test was then repeated.
  
  
  RESULTS
  In general, 51.9 % of assessed subjects had a negative result after the first test, and 100 % of these also had a negative result after the second test.
  
  
  CONCLUSIONS
  It was concluded that the use of almagate does not interfere in breath test results. These results provide a drug therapy option for the treatment of symptoms associated with Helicobacter pylori infection during the diagnostic process.
authors.forename: Carles
authors.initials: C
authors.lastname: Pons
authors.forename: Sandra
authors.initials: S
authors.lastname: Maisterra
authors.forename: Silvia
authors.initials: S
authors.lastname: Salord
authors.forename: Angels
authors.initials: A
authors.lastname: Pla
authors.forename: David
authors.initials: D
authors.lastname: Asensio
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Fernández
authors.forename: Gerard
authors.initials: G
authors.lastname: Traveria
authors.forename: Guillem
authors.initials: G
authors.lastname: Roura
mesh_terms: D000328:Adult; D000368:Aged; D000536:Aluminum Hydroxide / Q000032:analysis / Q000627:therapeutic use*; D000863:Antacids / Q000032:analysis / Q000627:therapeutic use*; D001944:Breath Tests / Q000379:methods*; D002254:Carbonates / Q000032:analysis / Q000627:therapeutic use*; D005188:False Negative Reactions; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori; D006801:Humans; D008276:Magnesium Hydroxide / Q000032:analysis / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results
chemical_list: D000863:Antacids; D002254:Carbonates; C043698:almagate; D000536:Aluminum Hydroxide; D008276:Magnesium Hydroxide