title: Botulinum neurotoxin A for chronic migraine headaches: does it work and how?
authors.affiliation: Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, V6T 1Z3, Canada.
authors.forename: Brian E
authors.initials: BE
authors.lastname: Cairns
authors.forename: Parisa
authors.initials: P
authors.lastname: Gazerani
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000494:pharmacology / Q000627:therapeutic use*; D019274:Botulinum Toxins, Type A / Q000494:pharmacology / Q000627:therapeutic use*; D002908:Chronic Disease; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy*; D009465:Neuromuscular Agents / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D018712:Analgesics, Non-Narcotic; D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A
keywords: chronic migraine; clinical trials; glutamate; headache; muscle; neurotoxin; neurotransmitter release; nociceptor; prophylaxis