title: A label-free fluorescent assay for free chlorine in drinking water based on protein-stabilized gold nanoclusters.
abstract: Bovine serum albumin stabilized Au nanoclusters (BSA-AuNCs) were demonstrated as a novel fluorescence probe for sensitive and selective detection of free chlorine in drinking water. The fluorescence of BSA-AuNCs was found to be quenched effectively by the free chlorine, and the decrease in fluorescence intensity of BSA-AuNCs allowed the sensitive detection of free chlorine in the range of 0.8-800 μM. The detection limit is 0.50 μM at a signal-to-noise ratio of 3. The present fluorescent assay for free chlorine possesses low detection limit, wide linear range and good selectivity. Real tap water samples were analyzed with satisfactory results, which suggested its potential for water quality analysis.
authors.affiliation: College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Xiong
authors.affiliation: College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Tang
authors.affiliation: Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education), College of Chemistry and Pharmacy, Guangxi Normal University, Guilin 541004, China.
authors.forename: Liangliang
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education), College of Chemistry and Pharmacy, Guangxi Normal University, Guilin 541004, China. Electronic address: zhaoshulin001@163.com.
authors.forename: Shulin
authors.initials: S
authors.lastname: Zhao
mesh_terms: D000818:Animals; D015374:Biosensing Techniques; D002417:Cattle; D002713:Chlorine / Q000032:analysis*; D060766:Drinking Water / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D059629:Signal-To-Noise Ratio; D013050:Spectrometry, Fluorescence
chemical_list: D060766:Drinking Water; D012710:Serum Albumin, Bovine; D002713:Chlorine; D006046:Gold
keywords: Au nanoclusters; Fluorescence probe; Free chlorine; Label-free fluorescent assay