title: The use of iron chelators in biocidal compositions: evaluation of patent, WO2014059417A1.
abstract: Anti-microbial-potentiating compositions, containing one or more anti-microbial agents and an iron chelator, are claimed in the patent application. Different combinations of anti-microbial agents with various classes of iron chelators are claimed. The use of such formulations enhances the biocidal activity of the anti-microbial agents. The compositions can be used for a number of applications, such as preservatives, personal care formulations, water-based paints, household cleaning products, and so on. These compositions have therapeutic use in the treatment of acne where they have been shown to markedly potentiate the effect of anti-microbial agents. They also have possible use in wound-healing products.
authors.affiliation: University of Sydney, Bosch Institute, Department of Pathology, Molecular Pharmacology and Pathology Program , Blackburn Building (D06), Sydney, New South Wales, 2006 , Australia.
authors.forename: Sumit
authors.initials: S
authors.lastname: Sahni
authors.forename: Sukriti
authors.initials: S
authors.lastname: Krishan
authors.forename: Duraippandi
authors.initials: D
authors.lastname: Palanimuthu
authors.forename: Des R
authors.initials: DR
authors.lastname: Richardson
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000494:pharmacology*; D004202:Disinfectants / Q000008:administration & dosage / Q000494:pharmacology*; D004357:Drug Synergism; D006801:Humans; D007502:Iron Chelating Agents / Q000008:administration & dosage / Q000494:pharmacology*; D010330:Patents as Topic; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D004202:Disinfectants; D007502:Iron Chelating Agents
keywords: anti-microbial agents; biocidal activity; iron chelators