title: Temporal control of neural progenitors: TGF-β switches the clock forward.
abstract: Little is known about how vertebrate neural progenitors in a given spatial domain change their identity over time. In this issue of Neuron, Dias et al. (2014) discover that hindbrain progenitors switch their output in response to TGF-β signaling.
authors.affiliation: Cellular Neurobiology Research Unit, Institut de recherches cliniques de Montréal (IRCM), 110 Avenue des Pins Ouest, Montréal, QC H2W 1R7, Canada. Electronic address: pierre.mattar@ircm.qc.ca.
authors.forename: Pierre
authors.initials: P
authors.lastname: Mattar
authors.affiliation: Cellular Neurobiology Research Unit, Institut de recherches cliniques de Montréal (IRCM), 110 Avenue des Pins Ouest, Montréal, QC H2W 1R7, Canada; Department of Medicine, Université de Montréal, Montreal, QC H3T 1P1, Canada; Division of Experimental Medicine and Department of Anatomy and Cell Biology, McGill University, Montreal, QC H3A 2B2, Canada. Electronic address: michel.cayouette@ircm.qc.ca.
authors.forename: Michel
authors.initials: M
authors.lastname: Cayouette
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000166:cytology*; D005260:Female; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D058953:Neural Stem Cells / Q000502:physiology*; D055495:Neurogenesis / Q000502:physiology*; D011247:Pregnancy; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D000077293:Receptor, Transforming Growth Factor-beta Type I; D018125:Receptors, Transforming Growth Factor beta / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D018125:Receptors, Transforming Growth Factor beta; D017346:Protein Serine-Threonine Kinases; D000077293:Receptor, Transforming Growth Factor-beta Type I