title: High prevalence of metabolic syndrome in a middle-aged and elderly population with prehypertension in Tianjin.
abstract: BACKGROUND
  Prehypertension has been reported as being correlated with future cardiovascular risk and end-organ damage in middle-aged and elderly persons, and also playing an important role in metabolic syndrome (MetS). The association between prehypertension and MetS has rarely been reported among urban adults in Tianjin, China.
  
  
  METHODS
  In this cross-sectional study, a total of 1176 participants aged 40-70 years (524 males and 652 females) were enrolled after excluding participants with hypertension or treated hypertension. Participants were divided into two groups [optimal blood pressure (BP) and prehypertension] based on the classification of BP from the JNC-7. The definition of MetS was as per the International Diabetes Federation standard. An adjusted logistic regression model was used to assess relationships between prehypertension and MetS.
  
  
  RESULTS
  The prehypertension group had a significantly higher odds ratio (OR) than the optimal BP group for abnormal waist circumference (WC), fasting plasma glucose (FPG) and triglycerides (TG). In addition, the prehypertension group had a higher OR (3.12; 95% confidence interval 2.34-4.18) for having MetS after adjusting for potential confounders.
  
  
  CONCLUSIONS
  The risk of having MetS was significantly associated with prehypertension in middle-aged and elderly persons in Tianjin. Stricter control of BP in this age group is warranted.
authors.affiliation: Department of Cardiology, Tianjin Medical University General Hospital, Tianjin Medial University , Tianjin , China.
authors.forename: Wei
authors.initials: W
authors.lastname: Yao
authors.forename: Yuemin
authors.initials: Y
authors.lastname: Sun
authors.forename: Xuechun
authors.initials: X
authors.lastname: Wang
authors.forename: Quan
authors.initials: Q
authors.lastname: Si
authors.forename: Huili
authors.initials: H
authors.lastname: Chen
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wan
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology* / Q000517:prevention & control; D008875:Middle Aged; D016017:Odds Ratio; D058246:Prehypertension / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology; D015995:Prevalence; D011322:Primary Prevention / Q000379:methods*; D012189:Retrospective Studies; D012307:Risk Factors; D055105:Waist Circumference
keywords: Metabolic syndrome; middle-aged and elderly; prehypertension; primary prevention; risk factor