title: Contemporary outcomes of open repair of thoracoabdominal aortic aneurysm in young patients.
abstract: BACKGROUND
  Endovascular technology now permits total endovascular thoracoabdominal aortic aneurysm (TAAA) repair with high volume centres reporting encouraging results. The long-term durability of such stent grafts is unknown, leading to concerns regarding their use in younger patients. This study reports contemporary outcomes of open repair in young patients.
  
  
  METHODS
  Outcomes for patients age 60 or younger undergoing open TAAA repair between June 1999 and August 2013 with prospective collected data were analysed retrospectively.
  
  
  RESULTS
  Thirty-seven patients (31 men, 84%) with a median age of 56 (range 22-60) were identified with a median TAAA diameter of 6.9 cm (range 5.6-11). Aneurysm aetiology included degenerative change (18), dilation of chronic dissection (10), connective tissue disease (7) and mycotic degeneration (2). Crawford Type IV TAAA were most commonly treated (17), followed by Type II (10), Type III (7) and Type I (3). Two (5%) patients died in hospital, one from multiple organ failure and one from respiratory failure. Three patients (8%) developed temporary paraplegia, all of whom made a complete recovery and 4 (11%) patients required temporary renal replacement therapy. Median critical care stay was 5 days (range 2-28) with an in-hospital stay of 14 days (range 7-83). During a median follow-up of 72 months (range 13-171), no patient subsequently required any further aneurysm related surgical or radiological intervention. The mean (SEM) survival time was 138.5 (11) months. The 5 year survival was 79.7% (8.3) including early deaths, with no aneurysm related complications.
  
  
  CONCLUSIONS
  The outcome of open TAAA repair in patients aged less than 60 years is favorable. It is against these results that evolving endovascular interventions must be compared.
authors.affiliation: Department of Vascular Surgery, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK. neiljohns@doctors.org.uk.
authors.forename: Neil
authors.initials: N
authors.lastname: Johns
authors.affiliation: Department of Vascular Surgery, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK. mrrwjamieson@googlemail.com.
authors.forename: Russell W
authors.initials: RW
authors.lastname: Jamieson
authors.affiliation: Department of Vascular Surgery, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK. carloceresa@hotmail.com.
authors.forename: Carlo
authors.initials: C
authors.lastname: Ceresa
authors.affiliation: Department of Vascular Surgery, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK. carl.moores@luht.scot.nhs.uk.
authors.forename: Carl
authors.initials: C
authors.lastname: Moores
authors.affiliation: Department of Vascular Surgery, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK. a.nimmo@ed.ac.uk.
authors.forename: Alastair F
authors.initials: AF
authors.lastname: Nimmo
authors.affiliation: Department of Vascular Surgery, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK. orwa.falah@nhslothian.scot.nhs.uk.
authors.forename: Orwa
authors.initials: O
authors.lastname: Falah
authors.affiliation: Department of Vascular Surgery, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK. paul.burns@luht.scot.nhs.uk.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Burns
authors.affiliation: Department of Vascular Surgery, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SB, UK. rod.chalmers@nhslothian.scot.nhs.uk.
authors.forename: Roderick T A
authors.initials: RT
authors.lastname: Chalmers
mesh_terms: D000328:Adult; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures