title: Introduction to fatty acids and lipids.
abstract: The purpose of this article is to describe the structure, function and metabolism of fatty acids and lipids that are of particular importance in the context of parenteral nutrition. Lipids are a heterogeneous group of molecules that share the common property of hydrophobicity. Lipids range in structure from simple short hydrocarbon chains to more complex molecules, including triacylglycerols, phospholipids and sterols and their esters. Lipids within each class may differ structurally. Fatty acids are common components of complex lipids, and these differ according to chain length and the presence, number and position of double bonds in the hydrocarbon chain. Structural variation among complex lipids and among fatty acids gives rise to functional differences that result in different impacts upon metabolism and upon cell and tissue responses. Fatty acids and complex lipids exhibit a variety of structural variations that influence their metabolism and their functional effects.
authors.affiliation: Academic Unit of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK.
authors.forename: Graham C
authors.initials: GC
authors.lastname: Burdge
authors.forename: Philip C
authors.initials: PC
authors.lastname: Calder
mesh_terms: D004952:Esters / Q000737:chemistry; D005227:Fatty Acids / Q000737:chemistry*; D006801:Humans; D008055:Lipids / Q000737:chemistry*; D010288:Parenteral Nutrition; D010743:Phospholipids / Q000737:chemistry; D013261:Sterols / Q000737:chemistry; D014280:Triglycerides / Q000737:chemistry
chemical_list: D004952:Esters; D005227:Fatty Acids; D008055:Lipids; D010743:Phospholipids; D013261:Sterols; D014280:Triglycerides