title: Safety and efficacy of quartz head contact laser ablation for large prostates using 980-nm laser: a comparative prospective study against that for small- and medium-sized prostates.
abstract: OBJECTIVE
  To examine the safety and efficacy of quartz head laser ablation of the prostate (QLAP) in the treatment of large and huge prostates as compared with small- and medium-sized ones.
  
  
  METHODS
  Two hundred forty-two patients with lower urinary tract symptoms secondary to benign prostatic hypertrophy (BPH) were included in the study, of which 210 patients were evaluable. Patients were divided into 2 groups: group A: patients with BPH volume of <80 mL (120 patients) and group B patients with gland size ≥80 mL. All patients were subjected to QLAP procedure. They were evaluated perioperatively and 1 week; 1, 3, and 6 months; and every 6 months thereafter postoperatively.
  
  
  RESULTS
  Patients' demographics and preoperative data were similar except for the gland size (group A, 54.96 ± 15.49 mL [20-79 mL] and group B, 124.68 ± 40.88 mL [80-233 mL]). Operative time corrected to gland volume was shorter in group B. Only 10% of all patients needed 2 fibers. There was no significant electrolyte change in both groups. Hemoglobin has minimally decreased in both groups but was statistically significant. Group B outcome was significantly better regarding International Prostate Symptom Score, International Prostate Symptom Score quality of life, and uroflowmetry. Prostate size decreased by 47 ± 2% and 62.7 ± 2% at 6 months post operatively for groups A and B, respectively.
  
  
  CONCLUSIONS
  QLAP demonstrated good efficacy and safety in treating large and huge BPH. It possessed no added risk as compared with small prostates. It can be a good alternative to open prostatectomy especially in patients with significant comorbidities.
authors.affiliation: Urology Department, Ain Shams University, Cairo, Egypt. Electronic address: hassanshaker@live.com.
authors.forename: Hassan S
authors.initials: HS
authors.lastname: Shaker
authors.affiliation: Urology Department, Ain Shams University, Cairo, Egypt.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Saafan
authors.affiliation: Urology Department, Ain Shams University, Cairo, Egypt.
authors.forename: Mohammed M
authors.initials: MM
authors.lastname: Yassin
authors.affiliation: Mataria Urology Institute, Cairo, Egypt.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Fawzy
authors.affiliation: Urology Department, Ain Shams University, Cairo, Egypt.
authors.forename: Mohammed S
authors.initials: MS
authors.lastname: Shoeb
mesh_terms: D000368:Aged; D006801:Humans; D053685:Laser Therapy; D059411:Lower Urinary Tract Symptoms / Q000209:etiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011446:Prospective Studies; D011467:Prostate / Q000473:pathology*; D011468:Prostatectomy / Q000379:methods*; D011470:Prostatic Hyperplasia / Q000150:complications / Q000473:pathology* / Q000601:surgery*; D011791:Quartz; D016896:Treatment Outcome
chemical_list: D011791:Quartz