title: Does type 1 diabetes alter post-exercise thermoregulatory and cardiovascular function in young adults?
abstract: Recent data demonstrated that individuals with type 1 diabetes mellitus (T1DM) exhibit impaired sweating and increased rectal temperature (i.e., heat storage) during exercise compared with healthy controls. Our purpose in this study was to investigate the consequences of T1DM on post-exercise thermal homeostasis. Sixteen participants (eight controls matched with eight T1DM) performed 90 min of cycling followed by 60 min of seated recovery. Esophageal and rectal temperatures, sweating (forearm, chest, and upper back), skin blood flow [forearm and upper back, presented as cutaneous vascular conductance (CVC)], and blood pressure [mean arterial pressure (MAP)] were measured at baseline and throughout recovery. Esophageal temperature was similar during baseline and recovery between groups (P = 0.88). However, rectal temperature was elevated in our T1DM group throughout recovery (P = 0.05). Sweating and CVC were similar between groups at all sites from 10-min post-exercise until the end of recovery (P ≥ 0.16). While absolute MAP was similar between groups (P = 0.43), the overall decrease in MAP post-exercise was greater in controls from 20 min (T1DM: - 8 ± 5 vs control: - 13 ± 6 mmHg, P = 0.03) until the end of recovery. We conclude that despite increased heat storage during exercise, individuals with T1DM exhibit a suppression in heat loss similar to their healthy counterparts during recovery.
authors.affiliation: Human and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, Ontario, Canada.
authors.forename: R
authors.initials: R
authors.lastname: McGinn
authors.affiliation: Human and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, Ontario, Canada.
authors.forename: M R
authors.initials: MR
authors.lastname: Carter
authors.affiliation: Human and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, Ontario, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Barrera-Ramirez
authors.affiliation: Departments of Medicine, Cardiac Sciences and Community Health Sciences, Faculties of Medicine and Kinesiology, University of Calgary, Calgary, Alberta, Canada.
authors.forename: R J
authors.initials: RJ
authors.lastname: Sigal
authors.affiliation: FAME Laboratory, Department of Exercise Science, University of Thessaly, Trikala, Greece.
authors.forename: A D
authors.initials: AD
authors.lastname: Flouris
authors.affiliation: Human and Environmental Physiology Research Unit, School of Human Kinetics, University of Ottawa, Ottawa, Ontario, Canada.
authors.forename: G P
authors.initials: GP
authors.lastname: Kenny
mesh_terms: D000328:Adult; D062186:Arterial Pressure; D001415:Back / Q000098:blood supply; D017704:Baroreflex; D001786:Blood Glucose / Q000378:metabolism; D001810:Blood Volume; D001831:Body Temperature; D001833:Body Temperature Regulation; D016022:Case-Control Studies; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D015444:Exercise / Q000502:physiology*; D005260:Female; D005542:Forearm / Q000098:blood supply; D006339:Heart Rate; D006801:Humans; D008297:Male; D009994:Osmolar Concentration; D012039:Regional Blood Flow; D012146:Rest / Q000502:physiology; D012867:Skin / Q000098:blood supply; D013318:Stroke Volume; D013546:Sweating; D014655:Vascular Resistance; D055815:Young Adult
chemical_list: D001786:Blood Glucose
keywords: hyperthermia; post-exercise hypotension; skin blood flow; sweating