title: Intraoperative red cell salvage during obstetric surgery in 50 Japanese women.
abstract: OBJECTIVE
  To determine the clinical usefulness of intraoperative cell salvage (ICS) in obstetrics.
  
  
  METHODS
  A retrospective analysis was performed using data for 50 patients who had received ICS blood during obstetric surgery at 13 Japanese facilities between January 1, 2007 and December 31, 2013. The frequencies of ICS-associated adverse events, allogeneic blood transfusion (ABT), and preoperative autologous donation (PAD) were assessed.
  
  
  RESULTS
  Placenta previa was the indication for ICS in 42 (84%) women. The ICS blood was reinfused in all women (median 366 mL; range 80 to at least 3715). No ICS-associated adverse events occurred. The median estimated blood loss (EBL) was 2171 mL (range 574-47 000); 27 (54%) women lost at least 2000 mL. ABT was not used in 33 (66%) women. Among 26 women who lost at least 2000 mL of blood and were included in analyses, 12 (44%) did not receive ABT. EBL was linearly correlated with the total volume of transfused blood (P<0.001).
  
  
  CONCLUSIONS
  ICS caused no adverse events among women at elevated risk of peripartum hemorrhage and might be safe for use in obstetrics.
authors.affiliation: Department of Obstetrics, Hokkaido University Hospital, Sapporo, Japan. Electronic address: mmamoru@med.hokudai.ac.jp.
authors.forename: Mamoru
authors.initials: M
authors.lastname: Morikawa
authors.affiliation: Department of Obstetrics and Gynecology, Kumamoto City Hospital, Kumamoto, Japan.
authors.forename: Akitaka
authors.initials: A
authors.lastname: Kuramoto
authors.affiliation: Department of Obstetrics and Gynecology, Yokohama Rosai Hospital, Yokohama, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Nakayama
authors.affiliation: Department of Obstetrics and Gynecology, Toyota Memorial Hospital, Toyota, Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Oguchi
authors.affiliation: Department of Obstetrics and Gynecology, Kurashiki Central Hospital, Kurashiki, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Hasegawa
authors.affiliation: Department of Obstetrics and Gynecology, Hyogo Prefectural Kobe Children's Hospital, Kobe, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Funakoshi
authors.affiliation: Department of Obstetrics and Gynecology, Miyazaki University Hospital, Miyazaki, Japan.
authors.forename: Seishi
authors.initials: S
authors.lastname: Furukawa
authors.affiliation: Department of Obstetrics and Gynecology, Sapporo City Hospital, Sapporo, Japan.
authors.forename: Emi
authors.initials: E
authors.lastname: Hirayama
authors.affiliation: Department of Obstetrics and Gynecology, Osaka University Hospital, Suita, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kanagawa
authors.affiliation: Department of Obstetrics and Gynecology, Tokushima University Hospital, Tokushima, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kaji
authors.affiliation: Department of Obstetrics and Gynecology, Iwate Prefectural Central Hospital, Morioka, Japan.
authors.forename: Mayumi
authors.initials: M
authors.lastname: Kasai
authors.affiliation: Department of Obstetrics and Gynecology, Saiseikai Yokohamashi Tobu Hospital, Yokohama, Japan.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Konishi
authors.affiliation: Department of Obstetrics and Gynecology, Kariya Toyota General Hospital, Kariya, Japan.
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Yamamoto
authors.affiliation: Department of Obstetrics and Gynecology, Juntendo University Hospital, Tokyo, Japan.
authors.forename: Atsuo
authors.initials: A
authors.lastname: Itakura
authors.affiliation: Department of Obstetrics and Gynecology, Mie Chuo Medical Center, Tsu, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Maeda
authors.affiliation: Department of Obstetrics and Gynecology, Hamamatsu Medical Center, Hamamatsu, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Kobayashi
authors.affiliation: Department of Obstetrics, Hokkaido University Hospital, Sapporo, Japan.
authors.forename: Hisanori
authors.initials: H
authors.lastname: Minakami
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical; D017707:Erythrocyte Transfusion / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D007564:Japan; D008875:Middle Aged; D013513:Obstetric Surgical Procedures / Q000379:methods*; D057725:Operative Blood Salvage / Q000009:adverse effects / Q000379:methods*; D010923:Placenta Previa / Q000601:surgery; D011247:Pregnancy; D012189:Retrospective Studies; D055815:Young Adult
keywords: Adverse events; Allogeneic blood transfusion; Amniotic fluid embolism; Autologous donation; Intraoperative cell salvage; Pregnancy