title: Peripapillary retinal nerve fibre layer thickness in women with iron deficiency anaemia.
abstract: OBJECTIVE
  To evaluate peripapillary retinal nerve fibre layer (RNFL) thickness in adult women with iron deficiency anaemia and healthy control subjects.
  
  
  METHODS
  Women with iron deficiency anaemia and age- and sex-matched healthy control subjects were sequentially recruited and underwent detailed ophthalmic examination, including spectral-domain optical coherence tomography (OCT). Serum haemoglobin (Hb), iron and ferritin concentrations, total iron-binding capacity (TIBC) and mean corpuscular volume were determined.
  
  
  RESULTS
  Peripapillary RNFL thicknesses in the nasal and inferior quadrants were significantly smaller in patients (n = 40) than in controls (n = 40). In the patient group, there were significant correlations between inferior quadrant RNFL thickness and Hb, and between nasal quadrant RNFL thickness and serum iron and ferritin concentrations, and TIBC.
  
  
  CONCLUSIONS
  Iron deficiency anaemia reduces RNFL thickness in adult women.
authors.affiliation: Department of Haematology, School of Medicine, Recep Tayyip Erdogan University, Rize, Turkey altunelif@hotmail.com.
authors.forename: Elif
authors.initials: E
authors.lastname: Akdogan
authors.affiliation: Department of Ophthalmology, School of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.
authors.forename: Kemal
authors.initials: K
authors.lastname: Turkyilmaz
authors.affiliation: Department of Internal Medicine, School of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.
authors.forename: Teslime
authors.initials: T
authors.lastname: Ayaz
authors.affiliation: Department of Internal Medicine, School of Medicine, Recep Tayyip Erdogan University, Rize, Turkey.
authors.forename: Damla
authors.initials: D
authors.lastname: Tufekci
mesh_terms: D000293:Adolescent; D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000473:pathology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D012160:Retina / Q000473:pathology*; D041623:Tomography, Optical Coherence; D055815:Young Adult
keywords: Iron deficiency anaemia; adult women; peripapillary retinal nerve fibre layer; spectral-domain optical coherence tomography