title: Scleral melt following Retisert intravitreal fluocinolone implant.
abstract: Intravitreal fluocinolone acetonide implant (Retisert) has a high potency, a low solubility, and a very short duration of action in the systemic circulation, enabling the steroid pellet to be small and reducing the risk of systemic side effects. Scleral melt has not been reported as a possible complication of Retisert implant. The authors describe the occurrence of scleral melt 18 months after the implantation of fluocinolone acetonide implant in a 42-year-old Caucasian woman. To the authors' knowledge, this is the first report of this possible complication.
authors.affiliation: Ophthalmology Department, University of Athens, Athens, Greece.
authors.forename: Ilias
authors.initials: I
authors.lastname: Georgalas
authors.affiliation: Ophthalmology Department, University of Athens, Athens, Greece.
authors.forename: Chrysanthi
authors.initials: C
authors.lastname: Koutsandrea
authors.affiliation: Ophthalmology Department, University of Athens, Athens, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Papaconstantinou
authors.affiliation: Ophthalmology Department, University of Athens, Athens, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Mpouritis
authors.affiliation: Ophthalmology Department, University of Athens, Athens, Greece ; Moorfields Eye Hospital, London, UK.
authors.forename: Petros
authors.initials: P
authors.lastname: Petrou
mesh_terms: D000328:Adult; D005260:Female; D005446:Fluocinolone Acetonide / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D058449:Intravitreal Injections; D015423:Scleritis / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
chemical_list: D005446:Fluocinolone Acetonide
keywords: Retisert; complication; scleral melt; surgical management