title: [Epidemiology of urolithiasis in Belgium on the basis of a morpho-constitutional classification].
abstract: Urolithiasis is a common condition, with a prevalence of ∼10% and a male/female ratio above 1 according to large national series. Various types of urinary stones have been described upon their mineral content and/or their morphology. Hence, a combined morpho-constitutional (M-C) classification has been proposed. In order to detail the prevalence of urolithiasis in general and of each M-C type in particular upon age and gender in Belgium, we retrospectively studied the database of a reference center for urolithiasis analysis. Between 2010 and 2013, 2195 stones were characterized. We excluded 45 non-biological stones and 281 stones, which originated from outside the study zone. Among 1869 stones, 1293 (69.2%) affected men. Prevalence peak of urolithiasis was observed between 50-60 years of age in both genders. The M-C analysis was available for 1854 stones (99.2%): multiple morphological types were concomitantly identified in 49.3%. In the whole population, the main mineral constituent was whewellite (54.4%), mainly organized as type Ia (94%). Weddellite was found in 19.8%, with an equal distribution between types IIa and IIb. Uric acid was the 3rd most frequent constituent in man, with a similar distribution between IIIa and IIIb. Phosphate was uncommon in man (8.2%), but frequent in woman (26.6%) with a type IVa1 organization. Prevalence of M-C types changes with aging, i.e. decrease of weddellite and increase of whewellite and uric acid in both genders. This retrospective analysis of a single-center database of urinary stones helps characterize the M-C epidemiology of urolithiasis in Belgium.
authors.affiliation: Département de biologie clinique, service de chimie clinique, centre hospitalier universitaire de Liège (ULg CHU), Liège, Belgique.
authors.forename: Vincent
authors.initials: V
authors.lastname: Castiglione
authors.affiliation: Département de médecine interne, service de néphrologie, ULg CHU, Liège, Belgique.
authors.forename: François
authors.initials: F
authors.lastname: Jouret
authors.affiliation: Unité de soutien méthodologique en épidémiologie et en biostatistiques, service de santé publique, épidémiologie et économie de la santé, université de Liège, Liège, Belgique.
authors.forename: Olivier
authors.initials: O
authors.lastname: Bruyère
authors.affiliation: Département de médecine interne, service de néphrologie, ULg CHU, Liège, Belgique.
authors.forename: Bernard
authors.initials: B
authors.lastname: Dubois
authors.affiliation: Département de chirurgie, service d'urologie, ULg CHU, Liège, Belgique.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Thomas
authors.affiliation: Département de chirurgie, service d'urologie, ULg CHU, Liège, Belgique.
authors.forename: David
authors.initials: D
authors.lastname: Waltregny
authors.affiliation: Département de biologie clinique, service de chimie clinique, centre hospitalier universitaire de Liège (ULg CHU), Liège, Belgique.
authors.forename: Anne-Catherine
authors.initials: AC
authors.lastname: Bekaert
authors.affiliation: Département de biologie clinique, service de chimie clinique, centre hospitalier universitaire de Liège (ULg CHU), Liège, Belgique.
authors.forename: Étienne
authors.initials: É
authors.lastname: Cavalier
authors.affiliation: Département de biologie clinique, service de chimie clinique, centre hospitalier universitaire de Liège (ULg CHU), Liège, Belgique. Electronic address: romy.gadisseur@chu.ulg.ac.be.
authors.forename: Romy
authors.initials: R
authors.lastname: Gadisseur
mesh_terms: D001530:Belgium / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D052878:Urolithiasis / Q000145:classification* / Q000453:epidemiology*
keywords: Calculs; Epidemiology; Gender ratio; Lithiase; Lithiasis; Prevalence; Prévalence; Rapport hommes/femmes; Urinary stones; Urolithiase; Urolithiasis; Épidémiologie