title: Chemical composition, antioxidant and antimicrobial activities of the edible medicinal Ononis natrix growing wild in Tunisia.
abstract: Results showed that leaf methanolic extract of Ononis natrix has important total phenol (51 mg GAE/g DW) and flavonoid (14.76 CE/g DW) contents. The chemical composition of O. natrix leaf revealed the presence of quercitine (24.5%), amentoflavone (14.1%), flavones (11.3%) and kaempferol (10.5%). The leaf extract showed a high total antioxidant activity with 60.94 mg of GAE/g DW, displayed a high 2,2-diphenyl-1-picrylhydrazyl scavenging ability with low IC50 value (29 μg/mL) and a great reducing power (EC50 = 100 μg/mL). O. natrix leaf extract exhibited a significant broad spectrum activity against all tested microorganisms with bacterial inhibition zone sizes ranging from 8.5 to 17 mm in diameter.
authors.affiliation: a Institut Supérieur de Biotechnologie de Béja, Université de Jendouba , Avenue Habib Bourguiba, BP: 382, Béja 9000 , Tunisie.
authors.forename: Baya
authors.initials: B
authors.lastname: Mhamdi
authors.forename: Feten
authors.initials: F
authors.lastname: Abbassi
authors.forename: Chedly
authors.initials: C
authors.lastname: Abdelly
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D007887:Fabaceae / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry; D010636:Phenols / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D013634:Tannins / Q000737:chemistry; D014416:Tunisia
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts; D013634:Tannins
keywords: Ononis natrix; antimicrobial activity; phenolic identification