title: Speciation via autoimmunity: a dangerous mix.
abstract: In this issue of Cell, Chae et al. find that genomic "hot spots" encoding NLR plant immune receptor genes are recurrently responsible for hybrid necrosis, highlighting the role of host-pathogen evolutionary arms races in driving the evolution of hybrid incompatibilities.
authors.affiliation: Department of Biology, University of Utah, Salt Lake City, UT 84112, USA. Electronic address: nitin.phadnis@utah.edu.
authors.forename: Nitin
authors.initials: N
authors.lastname: Phadnis
authors.affiliation: Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; HHMI, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Electronic address: hsmalik@fhcrc.org.
authors.forename: Harmit S
authors.initials: HS
authors.lastname: Malik
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000276:immunology*; D004843:Epistasis, Genetic