title: International coordination of large-scale human induced pluripotent stem cell initiatives: Wellcome Trust and ISSCR workshops white paper.
abstract: There is growing recognition of the potential value of human induced pluripotent stem cells (hiPSC) for understanding disease and identifying drugs targets. This has been reflected in the establishment of multiple large-scale hiPSC initiatives worldwide. Representatives of these met recently at a workshop supported by the Welcome Trust in the UK and in a focus session at the 2014 ISSCR annual meeting in Vancouver. The purpose was to discuss strategies for making thousands of hiPSC lines widely available with as few restrictions as possible while retaining financial viability and donor privacy. The outcome of these discussions is described here.
authors.affiliation: Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, Anne McLaren Laboratory for Regenerative Medicine and Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK.
authors.forename: Filipa A C
authors.initials: FA
authors.lastname: Soares
authors.affiliation: Department of Genetics and The Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey, Piscataway, NJ 08854-8009, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Sheldon
authors.affiliation: New York Stem Cell Foundation, New York, NY 10023, USA.
authors.forename: Mahendra
authors.initials: M
authors.lastname: Rao
authors.affiliation: Department of Anatomy and Embryology, Leiden University Medical Centre, Leiden 2300 RC, The Netherlands.
authors.forename: Christine
authors.initials: C
authors.lastname: Mummery
authors.affiliation: Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute, Anne McLaren Laboratory for Regenerative Medicine and Department of Surgery, University of Cambridge, Cambridge CB2 0QQ, UK; Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK. Electronic address: lv225@cam.ac.uk.
authors.forename: Ludovic
authors.initials: L
authors.lastname: Vallier
mesh_terms: D018929:Cell Culture Techniques; D002454:Cell Differentiation; D002460:Cell Line; D065150:Cellular Reprogramming; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology / Q000502:physiology