title: Bacterial colonization with balloon uterine stent placement in the uterus for 30 days: a randomized controlled clinical trial.
abstract: OBJECTIVE
  To assess bacterial colonization following balloon uterine stent placement in the uterus for 30 days.
  
  
  METHODS
  Prospective randomized controlled study.
  
  
  METHODS
  Tertiary medical center.
  
  
  METHODS
  Sixty-eight women scheduled for hysteroscopy.
  
  
  METHODS
  Women who were undergoing hysteroscopic surgery were randomly assigned to receive a balloon uterine stent or not. Before starting surgery, the uterine cavity was swabbed for bacterial culture. The device was placed in the uterus after surgery in the stent group. After 30 days, the stent was removed and sent for culture and the uterine cavity also swabbed and cultured. The uterine cavities of the control patients were swabbed before and 30 days after surgery.
  
  
  METHODS
  The primary outcome was the incidence of bacterial colonization of the uterus. Secondary outcomes were pain intensity and species of colonizing bacteria.
  
  
  RESULTS
  Excluding eight women, 30 women in each group were included in this analysis. In the stent group, three women (10.0%) demonstrated bacterial colonization before surgery compared with nine women (30.0%) after 30 days. In the control group, four (13.3%) and ten (33.3%) women had microorganisms detected in the uterus before and after 30 days after surgery, respectively. In neither group did the percentage of women with uterine microorganisms increase significantly after 30 days. The percentages of women with uterine bacterial colonization before and 30 days after surgery were similar between both groups.
  
  
  CONCLUSIONS
  Balloon uterine stents may be placed after surgery for up to 30 days without increasing bacterial colonization.
  
  
  BACKGROUND
  ClinicalTrials.gov (www.clinicaltrials.gov) NCT01167296.
authors.affiliation: Department of Obstetrics and Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan; Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, Taipei Medical University, Taipei, Taiwan.
authors.forename: Yu-Hung
authors.initials: YH
authors.lastname: Lin
authors.affiliation: Department of Infection Disease, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
authors.forename: Tsrang-Neng
authors.initials: TN
authors.lastname: Jang
authors.affiliation: Department of Obstetrics and Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; Department of Obstetrics and Gynecology, Taipei Medical University, Taipei, Taiwan.
authors.forename: Jiann-Loung
authors.initials: JL
authors.lastname: Hwang
authors.affiliation: Department of Obstetrics and Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
authors.forename: Lee-Wen
authors.initials: LW
authors.lastname: Huang
authors.affiliation: Department of Obstetrics and Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan.
authors.forename: Kok-Min
authors.initials: KM
authors.lastname: Seow
authors.affiliation: Department of Obstetrics and Gynecology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
authors.forename: Bih-Chwen
authors.initials: BC
authors.lastname: Hsieh
authors.affiliation: Department of Infection Disease, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan. Electronic address: jama001689@gmail.com.
authors.forename: Chien-Hsien
authors.initials: CH
authors.lastname: Huang
mesh_terms: D000328:Adult; D058491:Bacterial Load / Q000379:methods*; D004866:Equipment Contamination / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D011446:Prospective Studies; D015607:Stents / Q000382:microbiology*; D013997:Time Factors; D014599:Uterus / Q000382:microbiology* / Q000601:surgery
keywords: Intrauterine adhesions; bacteria colonization; balloon uterine stent; hysteroscopy; infection