title: Ru-catalyzed decarboxylative annulations of α-keto acids with internal alkynes: dual roles of COOH as directing group and leaving group.
abstract: Carboxylic acid serving as both directing and leaving group was discovered in Ru-catalyzed decarboxylative annulations of α-keto acids with alkynes. The well-established protocol showed high functional group tolerance, which provided an efficient and alternative route to the coumarone backbone.
authors.affiliation: Department of Chemistry, Huaibei Normal University, Huaibei, Anhui 235000 (P.R. China).
authors.forename: Hui
authors.initials: H
authors.lastname: Tan
authors.forename: Hongji
authors.initials: H
authors.lastname: Li
authors.forename: Jiawang
authors.initials: J
authors.lastname: Wang
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
keywords: alkynes; alpha-oxocarboxylic acids; annulation; decarboxylation; ruthenium catalysis