title: Choreography of AMPK activation.
abstract: A recent study published in Cell Research by Li and colleagues reports a detailed biophysical and structural study of AMPK's intra-molecular interactions during activation. By employing subunit tagging and proximity analysis with the aid of AlphaScreen instrumentation, Li et al. add to our understanding of the choreography of activation of AMPK by both nucleotides and phosphorylation.
authors.affiliation: St Vincent's Institute & Department of Medicine, The University of Melbourne, 41 Victoria Parade, Fitzroy, Victoria 3065, Australia.
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Langendorf
authors.affiliation: St Vincent's Institute & Department of Medicine, The University of Melbourne, 41 Victoria Parade, Fitzroy, Victoria 3065, Australia.
authors.forename: Bruce E
authors.initials: BE
authors.lastname: Kemp
mesh_terms: D055372:AMP-Activated Protein Kinases / Q000737:chemistry* / Q000378:metabolism*; D000249:Adenosine Monophosphate / Q000378:metabolism*; D006003:Glycogen / Q000378:metabolism*; D006801:Humans
chemical_list: D000249:Adenosine Monophosphate; D006003:Glycogen; D055372:AMP-Activated Protein Kinases