title: ICMA: an integrated cardiac modeling and analysis platform.
abstract: ICMA, a software framework to create 3D finite element models of the left ventricle from cardiac ultrasound or magnetic resonance imaging (MRI) data, has been made available as an open-source code. The framework is hardware vendor independent and uses speckle tracking (endocardial border detection) on ultrasound (MRI) imaging data in the form of DICOM. Standard American Heart Association segment-based strain analysis can be performed using a browser-based interface. The speckle tracking, border detection and model fitting methods are implemented in C++ using open-source tools. They are wrapped as web services and orchestrated via a JBOSS-based application server.
  
  
  METHODS
  The source code for ICMA is freely available under MPL 1.1 or GPL 2.0 or LGPL 2.1 license at https://github.com/ABI-Software-Laboratory/ICMA and a standalone virtual machine at http://goo.gl/M4lJKH for download.
  
  
  BACKGROUND
  r.jagir@auckland.ac.nz
  
  
  BACKGROUND
  Supplementary materials are available at Bioinformatics online.
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Jagir R
authors.initials: JR
authors.lastname: Hussan
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Hunter
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Patrick A
authors.initials: PA
authors.lastname: Gladding
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Neil
authors.initials: N
authors.lastname: Greenberg
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Christie
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Alan
authors.initials: A
authors.lastname: Wu
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Hugh
authors.initials: H
authors.lastname: Sorby
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: James D
authors.initials: JD
authors.lastname: Thomas
mesh_terms: D019295:Computational Biology / Q000379:methods*; D016208:Databases, Factual; D003952:Diagnostic Imaging; D006321:Heart / Q000033:anatomy & histology*; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006801:Humans; D008955:Models, Cardiovascular; D012984:Software