title: Efficacy of professionally administered plaque removal with or without adjunctive measures for the treatment of peri-implant mucositis. A systematic review and meta-analysis.
abstract: OBJECTIVE
  In patients with peri-implant mucositis, what is the efficacy of professionally administered plaque removal (PAPR) with adjunctive measures on changing signs of inflammation compared with PARP alone?
  
  
  METHODS
  After electronic database and hand search, 19 full-text articles were independently screened by two reviewers. Finally, a total of seven studies fulfilled the inclusion criteria. The weighted mean difference (WMD) in bleeding on probing- (BOP) (primary outcome), gingival index- (GI) and probing pocket depth- (PD) reductions was estimated (random effect model).
  
  
  RESULTS
  WMD in BOP reduction between test and control groups amounted to -8.16% [SD = 4.61; p = 0.07; 95% CI (-17.20, 0.88)] not favouring adjunctive antiseptic or antibiotic (local, systemic) therapy over PAPR alone. WMD in GI and PD reductions amounted to -0.12 [SD = 0.13; p = 0.34; 95% CI (-0.38, 0.13)] and -0.056 mm [SD = 0.10; p = 0.60; 95% CI (-0.27, 0.16)] not favouring adjunctive (antiseptics, systemic antibiotics, air abrasive device) over control measures respectively. Most studies evaluated reported on residual BOP and GI scores after therapy.
  
  
  CONCLUSIONS
  Adjunctive therapy may not improve the efficacy of PAPR in reducing BOP, GI and PD scores at mucositis sites. Despite clinically important improvements, a complete disease resolution may not be expected by any of the treatment protocols investigated.
authors.affiliation: Department of Oral Surgery, Heinrich Heine University, Düsseldorf, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Schwarz
authors.forename: Kathrin
authors.initials: K
authors.lastname: Becker
authors.forename: Martin
authors.initials: M
authors.lastname: Sager
mesh_terms: D020906:Air Abrasion, Dental; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D003131:Combined Modality Therapy; D015921:Dental Implants; D003773:Dental Plaque / Q000628:therapy*; D003777:Dental Prophylaxis / Q000379:methods*; D006801:Humans; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000628:therapy; D013280:Stomatitis / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D015921:Dental Implants
keywords: animal studies; clinical studies; peri-implant mucositis; systematic review