title: Brain structure in narcissistic personality disorder: a VBM and DTI pilot study.
abstract: We analysed T1-weighted MRI scans using voxel-based morphometry (VBM) and tract-based spatial statistics (TBBS) on diffusion tensor images (DTI) in narcissistic personality disorder (NaPD) patients and healthy controls. Grey matter deficits include right prefrontal and bilateral medial prefrontal/anterior cingulate cortices, and decreased fractional anisotropy in right frontal lobe white matter.
authors.affiliation: Department of Psychiatry and Psychotherapy, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany. Electronic address: igor.nenadic@uni-jena.de.
authors.forename: Igor
authors.initials: I
authors.lastname: Nenadic
authors.affiliation: Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Güllmar
authors.affiliation: Department of Psychiatry and Psychotherapy, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.
authors.forename: Maren
authors.initials: M
authors.lastname: Dietzek
authors.affiliation: Department of Psychiatry and Psychotherapy, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.
authors.forename: Kerstin
authors.initials: K
authors.lastname: Langbein
authors.affiliation: Department of Psychiatry and Psychotherapy, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.
authors.forename: Johanna
authors.initials: J
authors.lastname: Steinke
authors.affiliation: Department of Psychiatry and Psychotherapy, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany; Department of Neurology, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Gaser
mesh_terms: D000328:Adult; D056324:Diffusion Tensor Imaging / Q000379:methods; D005625:Frontal Lobe / Q000473:pathology*; D066128:Gray Matter / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009289:Narcissism; D010554:Personality Disorders / Q000473:pathology*; D010865:Pilot Projects; D066127:White Matter / Q000473:pathology*; D055815:Young Adult
keywords: Diffusion tensor imaging (DTI); Narcissistic personality disorder; Voxel-based morphometry (VBM)