title: Investigation of the presence of canine adenovirus (CAdV) in owned dogs in Northern Italy.
abstract: The use of a modified live canine adenovirus (CAdV) vaccine has greatly reduced the incidence of infectious canine hepatitis (ICH) in dogs. Nevertheless, cases of CAdV type 1 and 2 (CAdV-1 and CAdV-2) infection have been recently reported posing questions about the epidemiological situation of CAdV in dogs. In order to assess the presence of CAdV, samples from 51 dogs presented at a Veterinary Teaching Hospital in Bologna, Italy, for reasons unrelated with CAdV infection, were tested with a polymerase chain reaction (PCR) assay for CAdV. Thirty dogs (58.8%) were PCR positive for CAdV-2 infection and four of them (7.8%) were positive for CAdV-1. Sequence analysis performed on the obtained PCR products suggests that a genetically stable CAdV-1 strain and different CAdV-2 strains circulate in the canine population examined and that coinfections are relatively frequent.
authors.affiliation: Department of Veterinary Medical Sciences, Alma Mater Studiorum, University of Bologna, Via Tolara di Sopra 50, Ozzano dell'Emilia, Bologna 40064, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Balboni
authors.affiliation: Department of Veterinary Medical Sciences, Alma Mater Studiorum, University of Bologna, Via Tolara di Sopra 50, Ozzano dell'Emilia, Bologna 40064, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Mollace
authors.affiliation: Department of Veterinary Medical Sciences, Alma Mater Studiorum, University of Bologna, Via Tolara di Sopra 50, Ozzano dell'Emilia, Bologna 40064, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Giunti
authors.affiliation: Department of Veterinary Medical Sciences, Alma Mater Studiorum, University of Bologna, Via Tolara di Sopra 50, Ozzano dell'Emilia, Bologna 40064, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Dondi
authors.affiliation: Department of Veterinary Medical Sciences, Alma Mater Studiorum, University of Bologna, Via Tolara di Sopra 50, Ozzano dell'Emilia, Bologna 40064, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Prosperi
authors.affiliation: Department of Veterinary Medical Sciences, Alma Mater Studiorum, University of Bologna, Via Tolara di Sopra 50, Ozzano dell'Emilia, Bologna 40064, Italy. Electronic address: mara.battilani@unibo.it.
authors.forename: M
authors.initials: M
authors.lastname: Battilani
mesh_terms: D000257:Adenoviridae Infections / Q000453:epidemiology / Q000662:veterinary*; D062705:Adenovirus Vaccines / Q000008:administration & dosage; D006516:Adenoviruses, Canine / Q000235:genetics / Q000302:isolation & purification*; D000818:Animals; D060085:Coinfection / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D004283:Dog Diseases / Q000453:epidemiology* / Q000821:virology*; D004285:Dogs; D007558:Italy / Q000453:epidemiology; D016133:Polymerase Chain Reaction / Q000662:veterinary
chemical_list: D062705:Adenovirus Vaccines
keywords: Canine adenovirus; Coinfection; Dog; Italy; Molecular epidemiology