title: Intrauterine growth restriction and cerebral palsy.
abstract: Intrauterine growth restriction (IUGR) can be described as condition in which fetus fails to reach his potential growth. It is common diagnosis in obstetrics, and carries an increased risk of perinatal mortality and morbidity. Moreover, IUGR has lifelong implications on health, especially on neurological outcome. There is a need for additional neurological assessment during monitoring of fetal well-being, in order to better predict antenatally which fetuses are at risk for adverse neurological outcome. Studies have revealed that the behavior of the fetus reflects the maturational processes of the central nervous system (CNS). Hence, ultrasound investigation of the fetal behavior can give us insight into the integrity and functioning of the fetal CNS. Furthermore, investigations carried out using modern method, four-dimensional (4D) sonography, have produced invaluable details of fetal behavior and its development, opening the door to a better understanding of the prenatal functional development of the CNS. Based on previous observations and several years of investigation, our reaserch group has proposed a new scoring system for the assessment of fetal neurological status by 4D sonography named Kurjak antenatal neurodevelopmental test (KANET). The value of KANET in distinguishing fetal brain and neurodevelopmental alterations due to the early brain impairment in utero is yet to be assessed in large population studies. However, preliminary results are very encouraging.
authors.affiliation: Department Of Obstetrics and Gynecology, University Hospital "Sveti Duh", Medical School, University Of Zagreb, Zagreb, Croatia ; Feto Maternal Medicine Unit, Women'S Hospital, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Asim
authors.initials: A
authors.lastname: Kurjak
authors.affiliation: Department Of Physiology, Medical School, University Of Zagreb, Zagreb, Croatia.
authors.forename: Maja
authors.initials: M
authors.lastname: Predojevic
authors.affiliation: Division Of Neonatology, Department Of Obstetrics And Gynecology, Clinical Hospital "Sv. Duh", Zagreb, Croatia.
authors.forename: Milan
authors.initials: M
authors.lastname: Stanojevic
authors.affiliation: Department Of Physiology, Medical School, University Of Zagreb, Zagreb, Croatia ; Croatian Institute For Brain Research, Medical School, University Of Zagreb, Zagreb, Croatia.
authors.forename: Aida Salihagic-
authors.initials: AS
authors.lastname: Kadic
authors.affiliation: Department Of Obstetrics and Gynecology, University Hospital "Sveti Duh", Medical School, University Of Zagreb, Zagreb, Croatia.
authors.forename: Berivoj
authors.initials: B
authors.lastname: Miskovic
authors.affiliation: Feto Maternal Medicine Unit, Women'S Hospital, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Badreldeen
authors.affiliation: University Of Medical Sciences And Technology, Khartoum, Sudan.
authors.forename: Amira
authors.initials: A
authors.lastname: Talic
authors.affiliation: Department Of Obstetrics and Gynecology, University Hospital "Sveti Duh", Medical School, University Of Zagreb, Zagreb, Croatia.
authors.forename: Sanja
authors.initials: S
authors.lastname: Zaputovic
authors.affiliation: Welcare Hospital, Dubai, Uae.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Honemeyer
keywords: neurological risk; pregnancies complicated with IUGR