title: Reverse engineering of mandible and prosthetic framework: Effect of titanium implants in conjunction with titanium milled full arch bridge prostheses on the biomechanics of the mandible.
abstract: This study aimed at investigating the effects of titanium implants and different configurations of full-arch prostheses on the biomechanics of edentulous mandibles. Reverse engineered, composite, anisotropic, edentulous mandibles made of a poly(methylmethacrylate) core and a glass fibre reinforced outer shell were rapid prototyped and instrumented with strain gauges. Brånemark implants RP platforms in conjunction with titanium Procera one-piece or two-piece bridges were used to simulate oral rehabilitations. A lateral load through the gonion regions was used to test the biomechanical effects of the rehabilitations. In addition, strains due to misfit of the one-piece titanium bridge were compared to those produced by one-piece cast gold bridges. Milled titanium bridges had a better fit than cast gold bridges. The stress distribution in mandibular bone rehabilitated with a one-piece bridge was more perturbed than that observed with a two-piece bridge. In particular the former induced a stress concentration and stress shielding in the molar and symphysis regions, while for the latter design these stresses were strongly reduced. In conclusion, prosthetic frameworks changed the biomechanics of the mandible as a result of both their design and manufacturing technology.
authors.affiliation: Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, V.le J.F. Kennedy 54, Mostra d׳Oltremare (PAD. 20), 80125 Naples, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: De Santis
authors.affiliation: Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, V.le J.F. Kennedy 54, Mostra d׳Oltremare (PAD. 20), 80125 Naples, Italy. Electronic address: angloria@unina.it.
authors.forename: Antonio
authors.initials: A
authors.lastname: Gloria
authors.affiliation: Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, V.le J.F. Kennedy 54, Mostra d׳Oltremare (PAD. 20), 80125 Naples, Italy.
authors.forename: Teresa
authors.initials: T
authors.lastname: Russo
authors.affiliation: Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, V.le J.F. Kennedy 54, Mostra d׳Oltremare (PAD. 20), 80125 Naples, Italy.
authors.forename: Ugo
authors.initials: U
authors.lastname: D'Amora
authors.affiliation: Department of Oral Surgery and Implantology, University of Siena, Via Banchi di Sotto 55, 53100 Siena, Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Varriale
authors.affiliation: Department of Oral Surgery and Implantology, University of Siena, Via Banchi di Sotto 55, 53100 Siena, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Veltri
authors.affiliation: Department of Oral Surgery and Implantology, University of Siena, Via Banchi di Sotto 55, 53100 Siena, Italy.
authors.forename: Piero
authors.initials: P
authors.lastname: Balleri
authors.affiliation: Department of Materials Engineering, University of Ferrara, Via Saragat 1, 44100 Ferrara, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Mollica
authors.affiliation: Department of Oral and Maxillofacial Sciences, University of Naples "Federico II", Via Pansini 5, 80131 Naples, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Riccitiello
authors.affiliation: Institute of Polymers, Composites and Biomaterials, National Research Council of Italy, V.le J.F. Kennedy 54, Mostra d׳Oltremare (PAD. 20), 80125 Naples, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Ambrosio
mesh_terms: D057005:Bioengineering; D003776:Dental Porcelain; D017267:Dental Prosthesis Design; D019094:Dental Prosthesis, Implant-Supported; D006046:Gold; D006801:Humans; D008334:Mandible / Q000502:physiology*; D016876:Metal Ceramic Alloys; D066330:Printing, Three-Dimensional; D019736:Prostheses and Implants; D013314:Stress, Mechanical; D014025:Titanium
chemical_list: D016876:Metal Ceramic Alloys; C077451:Procera; D003776:Dental Porcelain; D006046:Gold; D014025:Titanium
keywords: Composite; Dental implants; Mandible; Stress concentration; Stress shielding