title: Endoscopic submucosal dissection for colorectal neoplasms: a review.
abstract: The introduction of colorectal endoscopic submucosal dissection (ESD) has expanded the application of endoscopic treatment, which can be used for lesions with a low metastatic potential regardless of their size. ESD has the advantage of achieving en bloc resection with a lower local recurrence rate compared with that of piecemeal endoscopic mucosal resection. Moreover, in the past, surgery was indicated in patients with large lesions spreading to almost the entire circumference of the rectum, regardless of the depth of invasion, as endoscopic resection of these lesions was technically difficult. Therefore, a prime benefit of ESD is significant improvement in the quality of life for patients who have large rectal lesions. On the other hand, ESD is not as widely applied in the treatment of colorectal neoplasms as it is in gastric cancers owing to the associated technical difficulty, longer procedural duration, and increased risk of perforation. To diversify the available endoscopic treatment strategies for superficial colorectal neoplasms, endoscopists performing ESD need to recognize its indications, the technical issues involved in its application, and the associated complications. This review outlines the methods and type of devices used for colorectal ESD, and the training required by endoscopists to perform this procedure.
authors.affiliation: Taku Sakamoto, Genki Mori, Masayoshi Yamada, Yuzuru Kinjo, Eriko So, Seiichiro Abe, Yosuke Otake, Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
authors.forename: Taku
authors.initials: T
authors.lastname: Sakamoto
authors.affiliation: Taku Sakamoto, Genki Mori, Masayoshi Yamada, Yuzuru Kinjo, Eriko So, Seiichiro Abe, Yosuke Otake, Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
authors.forename: Genki
authors.initials: G
authors.lastname: Mori
authors.affiliation: Taku Sakamoto, Genki Mori, Masayoshi Yamada, Yuzuru Kinjo, Eriko So, Seiichiro Abe, Yosuke Otake, Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Yamada
authors.affiliation: Taku Sakamoto, Genki Mori, Masayoshi Yamada, Yuzuru Kinjo, Eriko So, Seiichiro Abe, Yosuke Otake, Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
authors.forename: Yuzuru
authors.initials: Y
authors.lastname: Kinjo
authors.affiliation: Taku Sakamoto, Genki Mori, Masayoshi Yamada, Yuzuru Kinjo, Eriko So, Seiichiro Abe, Yosuke Otake, Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
authors.forename: Eriko
authors.initials: E
authors.lastname: So
authors.affiliation: Taku Sakamoto, Genki Mori, Masayoshi Yamada, Yuzuru Kinjo, Eriko So, Seiichiro Abe, Yosuke Otake, Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Abe
authors.affiliation: Taku Sakamoto, Genki Mori, Masayoshi Yamada, Yuzuru Kinjo, Eriko So, Seiichiro Abe, Yosuke Otake, Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Otake
authors.affiliation: Taku Sakamoto, Genki Mori, Masayoshi Yamada, Yuzuru Kinjo, Eriko So, Seiichiro Abe, Yosuke Otake, Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakajima
authors.affiliation: Taku Sakamoto, Genki Mori, Masayoshi Yamada, Yuzuru Kinjo, Eriko So, Seiichiro Abe, Yosuke Otake, Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
authors.forename: Takahisa
authors.initials: T
authors.lastname: Matsuda
authors.affiliation: Taku Sakamoto, Genki Mori, Masayoshi Yamada, Yuzuru Kinjo, Eriko So, Seiichiro Abe, Yosuke Otake, Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Saito
mesh_terms: D003082:Colectomy / Q000193:education / Q000379:methods*; D003113:Colonoscopy / Q000193:education / Q000379:methods*; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery*; D004210:Dissection / Q000193:education / Q000379:methods*; D004503:Education, Medical, Graduate; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome
keywords: Colorectum; Endoscopic submucosal dissection; Short-term outcomes; Training, indication for endoscopic treatment