title: Diagnostic value of high-resolution peripheral quantitative computed tomography (HR-pQCT) in the qualitative assessment of cribra orbitalia: a preliminary study.
abstract: Cribra orbitalia are a porotic or sieve-like lesions in the bony orbital roof. This characteristic has frequently been detected in palaeopathological skulls from many parts of the world and has been the object of extensive research. Our objective was to determine if high-resolution peripheral quantitative computed tomography (HR-pQCT) could produce reliable information in the study of cribra orbitalia. Seven skulls displaying cribra orbitalia were investigated by HR-pQCT. The two-dimensional slices were compared with histological sections. The HR-pQCT images and histological sections showed similar results, i.e. two groups of lesions with different characteristics. HR-pQCT can be of great value in palaeopathological research. It is a nondestructive, fast and precise technique that allows an easy evaluation of the bone architecture without destruction of the sample.
authors.affiliation: Laboratoire d'Anthropobiologie AMIS, UMR 5288 CNRS, Université Paul Sabatier, 37 allées Jules Guesde, 31000 Toulouse, France; Institut Médico-Légal, Hôpital Trousseau, CHRU de Tours, 37044 Tours Cedex 9, France. Electronic address: p.saint-martin@chu-tours.fr.
authors.forename: P
authors.initials: P
authors.lastname: Saint-Martin
authors.affiliation: Laboratoire d'Anthropobiologie AMIS, UMR 5288 CNRS, Université Paul Sabatier, 37 allées Jules Guesde, 31000 Toulouse, France; Service de Médecine Légale, CHU Toulouse-Rangueil, 1 avenue Professeur Jean Poulhès, 31059 Toulouse Cedex 9, France.
authors.forename: F
authors.initials: F
authors.lastname: Dedouit
authors.affiliation: Laboratoire d'Anthropobiologie AMIS, UMR 5288 CNRS, Université Paul Sabatier, 37 allées Jules Guesde, 31000 Toulouse, France; Institut Médico-Légal, Hôpital Trousseau, CHRU de Tours, 37044 Tours Cedex 9, France.
authors.forename: C
authors.initials: C
authors.lastname: Rérolle
authors.affiliation: Laboratoire d'Anthropobiologie AMIS, UMR 5288 CNRS, Université Paul Sabatier, 37 allées Jules Guesde, 31000 Toulouse, France.
authors.forename: C
authors.initials: C
authors.lastname: Guilbeau-Frugier
authors.affiliation: Laboratoire d'Anthropobiologie AMIS, UMR 5288 CNRS, Université Paul Sabatier, 37 allées Jules Guesde, 31000 Toulouse, France.
authors.forename: H
authors.initials: H
authors.lastname: Dabernat
authors.affiliation: Laboratoire d'Anthropobiologie AMIS, UMR 5288 CNRS, Université Paul Sabatier, 37 allées Jules Guesde, 31000 Toulouse, France; Service de Médecine Légale, CHU Toulouse-Rangueil, 1 avenue Professeur Jean Poulhès, 31059 Toulouse Cedex 9, France.
authors.forename: D
authors.initials: D
authors.lastname: Rougé
authors.affiliation: Laboratoire d'Anthropobiologie AMIS, UMR 5288 CNRS, Université Paul Sabatier, 37 allées Jules Guesde, 31000 Toulouse, France; Service de Médecine Légale, CHU Toulouse-Rangueil, 1 avenue Professeur Jean Poulhès, 31059 Toulouse Cedex 9, France.
authors.forename: N
authors.initials: N
authors.lastname: Telmon
authors.affiliation: Laboratoire d'Anthropobiologie AMIS, UMR 5288 CNRS, Université Paul Sabatier, 37 allées Jules Guesde, 31000 Toulouse, France.
authors.forename: E
authors.initials: E
authors.lastname: Crubézy
mesh_terms: D000293:Adolescent; D001847:Bone Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000266:history*; D002648:Child; D002675:Child, Preschool; D005602:France; D006652:Histological Techniques / Q000379:methods; D049668:History, 15th Century; D049690:History, Ancient; D049691:History, Medieval; D006801:Humans; D007223:Infant; D009915:Orbit / Q000000981:diagnostic imaging* / Q000473:pathology; D010164:Paleopathology / Q000379:methods*; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods*