title: Neurodegeneration in Huntington's disease involves loss of cystathionine γ-lyase.
authors.affiliation: a The Solomon H Snyder Department of Neuroscience ; Johns Hopkins University School of Medicine ; Baltimore , MD USA.
authors.forename: Bindu D
authors.initials: BD
authors.lastname: Paul
authors.forename: Solomon H
authors.initials: SH
authors.lastname: Snyder
mesh_terms: D000818:Animals; D003542:Cystathionine gamma-Lyase / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D006816:Huntington Disease / Q000201:enzymology* / Q000235:genetics / Q000473:pathology*; D051379:Mice; D009154:Mutation; D009410:Nerve Degeneration / Q000201:enzymology*
chemical_list: D003542:Cystathionine gamma-Lyase
keywords: CO, carbon monoxide; HD, Huntington's disease; Keap1, Kelch-like ECH-associated protein 1; NO, nitric oxide; Nrf2, nuclear factor erythroid 2-related factor 2; Rhes; TAF4, TBP associated factor 4; TBP, TATA box binding protein; corpus striatum; cystathionine γ-lyase; cysteine; hydrogen sulfide; specificity protein-1 (SP1)