title: [The patient with lung cancer in intensive care].
abstract: In Western countries, lung cancer (LC) is the most common cause of cancer death. It is present in 15-20% of patients admitted to the ICU with a neoplastic condition. The purpose of this article is to review the causes of admission to ICU of patients with LC, their prognosis and the results of different life-support techniques. Most studies include mixed populations of non-small cell (NSCLC) and small-cell lung cancers (SCLC). However, there is preponderance of NSCLC (70%) and LC of advanced or metastatic stages, reflecting the distribution in the general population of LC. The cause of admission of LC patients to ICU is most often of respiratory origin. The ICU mortality rate currently ranges from 13 to 47% and the hospital mortality rate from 24 to 65%. The predictors of in-hospital mortality are mainly severity scores, organ dysfunction, general condition (performance status), respiratory distress and the need for mechanical ventilation or vasopressor drugs. When considering the long-term mortality, it is the features of the cancer (presence of metastases, cancer progression) that are important predictive factors.
authors.affiliation: Service des soins intensifs et urgences oncologiques et oncologie thoracique, université libre de Bruxelles (ULB), institut Jules-Bordet, 1, rue Heger-Bordet, 1000 Brussel, Belgique. Electronic address: ap.meert@bordet.be.
authors.forename: A-P
authors.initials: AP
authors.lastname: Meert
authors.affiliation: Service des soins intensifs et urgences oncologiques et oncologie thoracique, université libre de Bruxelles (ULB), institut Jules-Bordet, 1, rue Heger-Bordet, 1000 Brussel, Belgique.
authors.forename: T
authors.initials: T
authors.lastname: Berghmans
authors.affiliation: Service des soins intensifs et urgences oncologiques et oncologie thoracique, université libre de Bruxelles (ULB), institut Jules-Bordet, 1, rue Heger-Bordet, 1000 Brussel, Belgique.
authors.forename: J-P
authors.initials: JP
authors.lastname: Sculier
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications / Q000453:epidemiology / Q000628:therapy; D003422:Critical Care / Q000706:statistics & numerical data; D006801:Humans; D007362:Intensive Care Units; D008175:Lung Neoplasms / Q000150:complications / Q000453:epidemiology / Q000628:therapy*; D010343:Patient Admission / Q000706:statistics & numerical data; D011184:Postoperative Period; D012121:Respiration, Artificial / Q000379:methods; D055752:Small Cell Lung Carcinoma / Q000150:complications / Q000453:epidemiology / Q000628:therapy; D013908:Thoracotomy / Q000534:rehabilitation
keywords: Acute respiratory failure; Cancer bronchique; Insuffisance respiratoire aiguë; Intensive care; Lung cancer; Mechanical ventilation; Mortality; Mortalité; Soins intensifs; Ventilation mécanique