title: Occipital calcified pseudoneoplasms of the neuraxis (CAPNON): understanding a rare pathology.
abstract: Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare and typically benign lesions that can occur anywhere within the central nervous system. Aetiology of this lesion is unclear and surgical removal is usually curative. We present a 24-year-old male patient with a history of occipital migraines who was admitted after sudden onset seizure and loss of vision. CT and MRI demonstrated a small calcifying lesion in the right temporo-occipital lobe. The patient underwent gross total resection of the tumour mass and pathological analysis revealed a CAPNON. The preoperative diagnosis of CAPNON remains difficult due to unspecific radiological findings, yet a clear understanding of characteristic pathological findings and prognosis of CAPNON remains paramount.
authors.affiliation: Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida, USA.
authors.forename: Kirill
authors.initials: K
authors.lastname: Lyapichev
authors.affiliation: Department of Neurological Surgery, University of Miami, Miller School of Medicine, Miami, Florida, USA.
authors.forename: Amade
authors.initials: A
authors.lastname: Bregy
authors.affiliation: Department of Neurological Surgery, University of Miami, Miller School of Medicine, Miami, Florida, USA.
authors.forename: Ashish H
authors.initials: AH
authors.lastname: Shah
authors.affiliation: Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida, USA.
authors.forename: Kinjal
authors.initials: K
authors.lastname: Shah
authors.affiliation: Department of Radiology, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Mehul B
authors.initials: MB
authors.lastname: Desai
authors.affiliation: Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida, USA.
authors.forename: Carol
authors.initials: C
authors.lastname: Petito
authors.affiliation: Department of Neurological Surgery, University of Miami, Miller School of Medicine, Miami, Florida, USA.
authors.forename: Ricardo J
authors.initials: RJ
authors.lastname: Komotar
mesh_terms: D001707:Biopsy, Needle; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D002114:Calcinosis / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D019635:Neurosurgical Procedures / Q000379:methods; D009778:Occipital Lobe / Q000473:pathology* / Q000601:surgery; D035583:Rare Diseases; D018570:Risk Assessment; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D055815:Young Adult