title: Rectal ulcer: Due to ketoprofen, argon plasma coagulation and prostatic brachytherapy.
abstract: Prostatic brachytherapy with permanent seed implants is a recent and safe radiation therapy technique associated with radiation-induced digestive disease. Argon plasma coagulation procedure is a validated modality in the management of haemorrhagic radiation proctitis, which is known to occasionally induce chronic rectal ulcers. We report here an original case report of an acute painful rectal ulcer as a consequence of the combination of short-term therapy with non-steroidal anti-inflammatory drugs therapy, prostatic brachytherapy with malposition of seed implants and argon plasma coagulation procedure in a patient with haemorrhagic radiation proctitis. The description of this clinical observation is essential to recommend the discontinuation of non-steroidal anti-inflammatory drugs therapy and the control of the position of seed implants in case of prostatic brachytherapy before argon plasma coagulation for radiation-induced proctitis.
authors.affiliation: Thibaud Koessler, Wulfran Cacheux, Department of Oncology, Hôpitaux universitaires de Genève, 1205 Geneva, Switzerland.
authors.forename: Thibaud
authors.initials: T
authors.lastname: Koessler
authors.affiliation: Thibaud Koessler, Wulfran Cacheux, Department of Oncology, Hôpitaux universitaires de Genève, 1205 Geneva, Switzerland.
authors.forename: Vincent
authors.initials: V
authors.lastname: Servois
authors.affiliation: Thibaud Koessler, Wulfran Cacheux, Department of Oncology, Hôpitaux universitaires de Genève, 1205 Geneva, Switzerland.
authors.forename: Pascale
authors.initials: P
authors.lastname: Mariani
authors.affiliation: Thibaud Koessler, Wulfran Cacheux, Department of Oncology, Hôpitaux universitaires de Genève, 1205 Geneva, Switzerland.
authors.forename: Emilie
authors.initials: E
authors.lastname: Aubert
authors.affiliation: Thibaud Koessler, Wulfran Cacheux, Department of Oncology, Hôpitaux universitaires de Genève, 1205 Geneva, Switzerland.
authors.forename: Wulfran
authors.initials: W
authors.lastname: Cacheux
mesh_terms: D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D057908:Argon Plasma Coagulation / Q000009:adverse effects*; D001918:Brachytherapy / Q000009:adverse effects*; D006470:Hemorrhage / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007660:Ketoprofen / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D008297:Male; D011349:Proctitis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D011471:Prostatic Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D012002:Rectal Diseases / Q000175:diagnosis / Q000209:etiology*; D012307:Risk Factors; D012812:Sigmoidoscopy; D014456:Ulcer / Q000175:diagnosis / Q000209:etiology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007660:Ketoprofen
keywords: Argon plasma coagulation; Non-steroidal anti-inflammatory drugs; Prostatic brachytherapy; Radiation proctitis