title: Pharmacomechanical thrombectomy and catheter-directed thrombolysis of acute lower extremity deep venous thrombosis in a 9-year-old boy with inferior vena cava atresia.
abstract: Lower extremity deep venous thrombosis (DVT) is uncommon in the pediatric population, but it can be associated with severe symptoms and potential long-term morbidity secondary to post-thrombotic syndrome. Inferior vena cava (IVC) atresia can predispose a patient to the development of extremity DVT. There is no clear consensus on optimal management of extensive extremity DVT in pediatric patients, especially in patients with IVC anomalies. We report a case of iliofemoral DVT in a 9-year-old boy with IVC atresia and presumed protein S deficiency that was treated successfully using pharmacomechanical thrombectomy and catheter-directed thrombolysis. He was maintained on long-term anticoagulation and remained symptom free at 6 months' follow-up.
authors.affiliation: Louisiana State University Health Shreveport, Shreveport, Louisiana, USA.
authors.forename: Alireza
authors.initials: A
authors.lastname: Hamidian Jahromi
authors.affiliation: Louisiana State University Health Shreveport, Shreveport, Louisiana, USA.
authors.forename: Amy H
authors.initials: AH
authors.lastname: Coulter
authors.affiliation: Louisiana State University Health Shreveport, Shreveport, Louisiana, USA.
authors.forename: Patrick
authors.initials: P
authors.lastname: Bass
authors.affiliation: Louisiana State University Health Shreveport, Shreveport, Louisiana, USA.
authors.forename: Wayne W
authors.initials: WW
authors.lastname: Zhang
authors.affiliation: Louisiana State University Health Shreveport, Shreveport, Louisiana, USA ttan1@lsuhsc.edu.
authors.forename: Tze-Woei
authors.initials: TW
authors.lastname: Tan
mesh_terms: D000208:Acute Disease; D057785:Catheters; D002648:Child; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D017131:Thrombectomy / Q000379:methods; D015912:Thrombolytic Therapy / Q000379:methods; D014682:Vena Cava, Inferior; D020246:Venous Thrombosis / Q000175:diagnosis / Q000628:therapy*
chemical_list: D005343:Fibrinolytic Agents
keywords: inferior vena cava atresia; pediatric deep venous thrombosis; percutaneous thrombectomy