title: Stem cell RNA epigenetics: m(6)arking your territory.
abstract: Modifications of mRNAs can have a profound effect on cellular function and differentiation. In this issue of Cell Stem Cell, Batista et al. (2014) describe fundamental parameters of N(6)-methyl-adenosine modification of mRNAs in embryonic stem cells and provide strong evidence that modification plays a role in exit from pluripotency toward differentiation.
authors.affiliation: Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
authors.forename: Aimee L
authors.initials: AL
authors.lastname: Jalkanen
authors.affiliation: Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA. Electronic address: jeffrey.wilusz@colostate.edu.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Wilusz
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives*; D000818:Animals; D053595:Embryonic Stem Cells / Q000502:physiology*; D005260:Female; D018398:Homeodomain Proteins / Q000378:metabolism*; D006801:Humans; D008780:Methyltransferases / Q000378:metabolism*
chemical_list: D018398:Homeodomain Proteins; D008780:Methyltransferases; D000225:Adenine