title: Multidisciplinary perspective on the management of appendiceal adenocarcinoma: case review of 10 patients from a university hospital and current considerations.
abstract: BACKGROUND
  Adenocarcinoma of the vermiform appendix is rare. It constitutes less than 0.5% of all gastrointestinal malignancies. Pathologically, appendiceal neoplasms are categorized into various subtypes depending on cell lineage.
  
  
  METHODS
  We considered a case series of appendiceal invasive adenocarcinomas from 2004 to 2013 managed in a teaching hospital. We discuss our management dilemmas, given the lack of randomized controlled trial data that exist. A detailed look at the histopathology, case series, and literature is presented.
  
  
  RESULTS
  Ideal standards ought to be constructed for the management of this rare pathology, with a particular focus on exploring the indications and potential benefits, as well as difficulties, of ileocolic lymphadenectomy.
  
  
  CONCLUSIONS
  Appendiceal adenocarcinoma ought to be managed in the same way as a cecal adenocarcinoma.
authors.affiliation: Department of Colorectal Surgery, Bristol Royal Infirmary, Bristol, United Kingdom. Electronic address: johnbunni@hotmail.com.
authors.forename: John
authors.initials: J
authors.lastname: Bunni
authors.affiliation: Department of Colorectal Surgery, Bristol Royal Infirmary, Bristol, United Kingdom.
authors.forename: David
authors.initials: D
authors.lastname: Arnold
authors.affiliation: Department of Pathology, Bristol Royal Infirmary, Bristol, United Kingdom.
authors.forename: Golda
authors.initials: G
authors.lastname: Shelley-Fraser
authors.affiliation: Department of Colorectal Surgery, Bristol Royal Infirmary, Bristol, United Kingdom.
authors.forename: Jamshed
authors.initials: J
authors.lastname: Shabbir
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000628:therapy*; D000328:Adult; D000368:Aged; D001063:Appendiceal Neoplasms / Q000473:pathology / Q000628:therapy*; D002430:Cecal Neoplasms / Q000473:pathology / Q000628:therapy*; D005260:Female; D006785:Hospitals, University; D006801:Humans; D033183:Interdisciplinary Communication; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness
keywords: Adenocarcinoma; Appendiceal cancer; Appendix; GI malignancy; Ileocolic lymphadenectomy