title: Intra-articular platelet-rich plasma injection for the treatment of temporomandibular disorders and a comparison with arthrocentesis.
abstract: BACKGROUND
  Temporomandibular joint (TMJ) internal derangements are progressive painful conditions and cause joint dysfunction, joint sound, malocclusion, and locking of the mouth. Conservative and invasive techniques can be used for the treatment of TMJ internal derangements. The objective of the present study was to examine the benefit of an intra-articular platelet-rich plasma (PRP) injection and to compare this with arthrocentesis.
  
  
  METHODS
  Twenty patients (female: male; 15:5; age 26, 3 ± 9.3 years) for a total of 32 joints with reducible anterior disc dislocation, as confirmed by Magnetic Resonance Imaging (MRI), were divided into two groups. PRP was used for the study group, and arthrocentesis was used for the control group. Pain intensity, maximal interincisal opening, and TMJ sounds were assessed and compared for evaluation of treatment success.
  
  
  RESULTS
  There was a statistically significant reduction in pain intensity and joint sound and an increase in mouth opening in the study group when compared with the control group.
  
  
  CONCLUSIONS
  This study shows that intra-articular PRP injection for the treatment of reducible disc displacement of the TMJ is a more effective method than arthrocentesis.
authors.affiliation: Istanbul Medipol University, Faculty of Medicine, Department of Plastic Reconstructive and Aesthetic Surgery, Istanbul, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Hancı
authors.affiliation: Selcuk University, Faculty of Medicine, Department of Plastic Reconstructive and Aesthetic Surgery, Alaaddin Keykubat Kampüsü, Selçuklu, Konya, Turkey. Electronic address: mehtapef@yahoo.com.
authors.forename: Mehtap
authors.initials: M
authors.lastname: Karamese
authors.affiliation: Selcuk University, Faculty of Medicine, Department of Plastic Reconstructive and Aesthetic Surgery, Alaaddin Keykubat Kampüsü, Selçuklu, Konya, Turkey.
authors.forename: Zekeriya
authors.initials: Z
authors.lastname: Tosun
authors.affiliation: Necmettin Erbakan University, Faculty of Medicine, Department of Human Histology and Embryology, Meram Tıp Fakültesi, Akyokuş, Meram, Konya, Turkey.
authors.forename: Tahsin Murad
authors.initials: TM
authors.lastname: Aktan
authors.affiliation: Necmettin Erbakan University, Faculty of Medicine, Department of Human Histology and Embryology, Meram Tıp Fakültesi, Akyokuş, Meram, Konya, Turkey.
authors.forename: Selcuk
authors.initials: S
authors.lastname: Duman
authors.affiliation: Necmettin Erbakan University, Faculty of Medicine, Department of Plastic Reconstructive and Aesthetic Surgery, Meram Tıp Fakültesi, Akyokuş, Meram, Konya, Turkey.
authors.forename: Nedim
authors.initials: N
authors.lastname: Savaci
mesh_terms: D000293:Adolescent; D000328:Adult; D000069237:Arthrocentesis / Q000379:methods*; D004032:Diet; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007270:Injections, Intra-Articular; D004204:Joint Dislocations / Q000503:physiopathology / Q000628:therapy; D008297:Male; D017090:Occlusal Splints; D010147:Pain Measurement / Q000379:methods; D053657:Platelet-Rich Plasma / Q000502:physiology*; D011446:Prospective Studies; D016059:Range of Motion, Articular / Q000502:physiology; D013016:Sound; D019224:Temporomandibular Joint Disc / Q000473:pathology; D013705:Temporomandibular Joint Disorders / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Arthrocentesis; Internal derangement; Platelet-rich plasma; Temporomandibular joint disorder