title: Isonitrile iron(II) complexes with chiral N2P2 macrocycles in the enantioselective transfer hydrogenation of ketones.
abstract: Bis(isonitrile) iron(II) complexes bearing a C2-symmetric N2P2 macrocyclic ligand, which are easily prepared from the corresponding bis(acetonitrile) analogue, catalyze the asymmetric transfer hydrogenation (ATH) of a broad scope of ketones in excellent yields (up to 98%) and with high enantioselectivity (up to 91% ee).
authors.affiliation: Department of Chemistry and Applied Biosciences, ETH Zürich , CH-8093 Zürich, Switzerland.
authors.forename: Raphael
authors.initials: R
authors.lastname: Bigler
authors.forename: Antonio
authors.initials: A
authors.lastname: Mezzetti
mesh_terms: D002384:Catalysis; D005296:Ferrous Compounds / Q000737:chemistry*; D006865:Hydrogenation; D007659:Ketones / Q000737:chemistry*; D008024:Ligands; D047028:Macrocyclic Compounds / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D005296:Ferrous Compounds; D007659:Ketones; D008024:Ligands; D047028:Macrocyclic Compounds; D009570:Nitriles