title: Germline retinoblastoma without inherited gene mutation: a case report.
abstract: Retinoblastoma is the most common primary ocular malignancy in childhood and can occur as a germline or somatic mutation. Recent studies have suggested a higher incidence of retinoblastoma in Hispanic children as compared to non-Hispanic white children of the same ages. We report the ocular findings of a 20 years old Hispanic male with a history of bilateral retinoblastoma. Although screening is currently performed with the red reflex test, analysis of current literature suggests the need to reassess screening recommendations for retinoblastoma.
authors.forename: José A
authors.initials: JA
authors.lastname: Quintero-Estades
authors.forename: Natalio J
authors.initials: NJ
authors.lastname: Izquierdo
mesh_terms: D018095:Germ-Line Mutation; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods; D009154:Mutation; D012175:Retinoblastoma / Q000453:epidemiology / Q000235:genetics* / Q000473:pathology; D055815:Young Adult