title: Mortality and causes of death of Dutch burn patients during the period 2006-2011.
abstract: BACKGROUND
  Mortality of burn patients has decreased in the last decades. Literature indicates that the leading cause of death in late mortality is multiple organ failure (MOF), but literature is not clear about the cause of early mortality. The aim of this study was to determine the mortality and causes of death of burn patients in Dutch burn centers between January 2006 and December 2011.
  
  
  METHODS
  A retrospective study was performed in patients who died between January 2006 and December 2011 in the burn centers of Rotterdam and Beverwijk, the Netherlands. In this period 2730 patients were admitted.
  
  
  RESULTS
  Of these 2730 patients, 88 patients died as a result of their burn injury. The overall mortality rate was 3.2%. The palliative care group, defined as patients receiving no curative ('active') care and leading to early death (<48h), consisted of 28 patients (31.8%, 28 out of 88 patients). The most common cause of late mortality (>48h, in 60 out of 88 patients, 68.2%) was MOF (38.3%, 23 out of 60 patients). One important significant difference between the early and late mortality groups was a higher Baux score in the palliative care group compared to the withdrawal of and active treatment groups. There were no significant differences when the groups were compared regarding the presence of inhalation trauma.
  
  
  CONCLUSIONS
  Mortality in burn patients has decreased. Most deaths occur early, in patients who receive only palliative care. In late mortality, MOF is the most common cause of death.
authors.affiliation: Burn Center, Maasstad Hospital, Rotterdam, The Netherlands.
authors.forename: Jan
authors.initials: J
authors.lastname: Dokter
authors.affiliation: Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Miriam
authors.initials: M
authors.lastname: Felix
authors.affiliation: Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Pieta
authors.initials: P
authors.lastname: Krijnen
authors.affiliation: Burn Center, Red Cross Hospital, Beverwijk, The Netherlands.
authors.forename: Jos F P M
authors.initials: JF
authors.lastname: Vloemans
authors.affiliation: Association Dutch Burn Centers, Maasstad Hospital, Rotterdam, The Netherlands.
authors.forename: Margriet E van
authors.initials: ME
authors.lastname: Baar
authors.affiliation: Association Dutch Burn Centers, Beverwijk, The Netherlands.
authors.forename: Wim E
authors.initials: WE
authors.lastname: Tuinebreijer
authors.affiliation: Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands; Red Cross Hospital Beverwijk, Department of Surgery-Traumatology, Beverwijk, The Netherlands. Electronic address: rbreederveld@rkz.nl.
authors.forename: Roelf S
authors.initials: RS
authors.lastname: Breederveld
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D002053:Burn Units / Q000706:statistics & numerical data; D002056:Burns / Q000401:mortality*; D002059:Burns, Inhalation / Q000401:mortality; D002423:Cause of Death; D005260:Female; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000401:mortality; D009426:Netherlands / Q000453:epidemiology; D010166:Palliative Care / Q000706:statistics & numerical data; D012189:Retrospective Studies; D018805:Sepsis / Q000401:mortality; D055815:Young Adult
keywords: Burn; Mortality; Multiple organ failure; Palliative care; Withholding treatment