title: Fibrous dysplasia of the temporal bone: a review of 66 cases.
abstract: OBJECTIVE
  Fibrous dysplasia is a condition of nonmalignant osseous change and may occur in a monostotic or polyostotic pattern, the latter potentially being associated with McCune-Albright syndrome. Symptoms are highly variable and dependent upon lesion location and size.
  
  
  METHODS
  Retrospective review.
  
  
  METHODS
  Consecutive subjects with fibrous dysplasia of the temporal bone were evaluated between 2000 and 2013 at two tertiary academic referral centers. Main outcome measures included disease presentation, diagnostic evaluation, management strategy, and outcome.
  
  
  RESULTS
  Sixty-six patients with fibrous dysplasia of the skull were found to have involvement of the temporal bone. The mean age at diagnosis was 25 years, 39 (59%) were female, and the mean duration of follow-up was 48 months. Six (11%) patients had monostotic disease, with the remaining 60 (89%) patients having the polyostotic form; 16 (24%) patients had McCune-Albright syndrome. The most common presenting complaint was headache (59%), followed by hearing loss (29%). The most common exam finding was cosmetic deformity (50%). Cholesteatoma (3%) and spontaneous cerebrospinal fluid fistula (1.5%) were found in a small percentage. No patients had evidence of motor cranial neuropathy by history or physical examination.
  
  
  CONCLUSIONS
  The clinical presentation of fibrous dysplasia involving the temporal bone is variable. A growing number of patients are diagnosed incidentally through imaging, and since most patients experience a benign course, the majority can be followed clinically without need for intervention.
  
  
  METHODS
  4.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic School of Medicine, Rochester, Minnesota.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Frisch
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic School of Medicine, Rochester, Minnesota.
authors.forename: Matthew L
authors.initials: ML
authors.lastname: Carlson
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, U.S.A.
authors.forename: Charissa N
authors.initials: CN
authors.lastname: Kahue
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, U.S.A.
authors.forename: Stanley
authors.initials: S
authors.lastname: Pelosi
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, U.S.A.
authors.forename: David S
authors.initials: DS
authors.lastname: Haynes
authors.affiliation: Department of Radiology, Mayo Clinic School of Medicine, Rochester, Minnesota.
authors.forename: John I
authors.initials: JI
authors.lastname: Lane
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic School of Medicine, Rochester, Minnesota.
authors.forename: Brian A
authors.initials: BA
authors.lastname: Neff
authors.affiliation: Department of Neurologic Surgery, Mayo Clinic School of Medicine, Rochester, Minnesota.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Link
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic School of Medicine, Rochester, Minnesota.
authors.forename: Colin L W
authors.initials: CL
authors.lastname: Driscoll
mesh_terms: D000328:Adult; D005260:Female; D005358:Fibrous Dysplasia, Monostotic / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D033162:Incidental Findings; D008297:Male; D012189:Retrospective Studies; D013701:Temporal Bone; D055815:Young Adult
keywords: Temporal bone; cranial base; fibrous dysplasia; osteodystrophy; skull base