title: Disease extent and local complication of ulcerative colitis in Bangladeshi population.
abstract: Ulcerative colitis may involve anywhere from the rectum alone to the entire colon. Local complications like perforation, life threatening haemorrhage, toxic megacolon, pseudo polyps, stricture, and carcinoma of colon are seen. Patients who were diagnosed as Ulcerative Colitis in Departmental Ulcerative Colitis record book from January 1990 to June 2010 was considered as study population. Information regarding the extent of the disease and local complications were taken from earliest documented Lower GIT Endoscopy. Out of 164 patients disease extent were seen in 126(76.83%) patients and among them proctitis/proctosigmoiditis were seen in 57(45.24%) patients, left sided colitis were seen in 11(8.73%) patients, extensive/pan colitis were seen in 58(46.03%) patients. Complication were seen in 164 patients and 1(0.60%) patient had life threatening haemorrhage, 25(15.24%) patients developed pseudo polyps. There was no report of perforation, toxic megacolon, stricture or carcinoma of colon. The differences found between our study and studies from other Western and Asian countries in terms of complication rate and disease extent for were probably due to low index of suspicion, incomplete workup, or incomplete records, and influence of various environmental factors. So, further large scale prospective evaluation is suggested.
authors.affiliation: Dr Mohammad Shoaib Chowdhury, Medical Officer, Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail: drshoaibchowdhury@gmail.com.
authors.forename: M S
authors.initials: MS
authors.lastname: Chowdhury
authors.forename: M R
authors.initials: MR
authors.lastname: Khan
authors.forename: M
authors.initials: M
authors.lastname: Mahmuduzzaman
authors.forename: M Z
authors.initials: MZ
authors.lastname: Rahman
authors.forename: S M
authors.initials: SM
authors.lastname: Ishaque
authors.forename: A R
authors.initials: AR
authors.lastname: Miah
authors.forename: P K
authors.initials: PK
authors.lastname: Roy
authors.forename: M A
authors.initials: MA
authors.lastname: Raihan
mesh_terms: D000328:Adult; D001459:Bangladesh / Q000453:epidemiology; D003093:Colitis, Ulcerative / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D003113:Colonoscopy / Q000379:methods; D018450:Disease Progression; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D007420:Intestine, Large / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index