title: Isolated repeated anastomotic recurrence after sigmoidectomy.
abstract: Repeated anastomotic recurrence (AR) of colonic cancer is uncommon. We report a case of a double-isolated AR after sigmoidectomy. In 2003, a 60-year-old woman underwent stapled sigmoid resection for a moderately differentiated adenocarcinoma. Further rectal bleeding occurred after six months, and colonoscopy detected an AR. Thus, an additional stapled colorectal anastomosis was performed. Ten months later, a colonoscopy detected a circumferential AR that prompted the completion of a second colorectal resection, with a double-stapled colorectal anastomosis. Twenty-four hours after surgery, a massive pulmonary embolism occurred, and the patient died within a few hours. At present, only six cases of repeated isolated AR have been described. Repeated segmental colorectal resections are generally associated with a favourable prognosis, with a median survival rate of 45 mo (range, 13-132 mo). Repeated isolated ARs are rare, and segmental colorectal resections are generally associated with long-term disease-free survival.
authors.affiliation: Giovanni Conzo, Claudio Mauriello, Claudio Gambardella, Fabio Cavallo, Ernesto Tartaglia, Salvatore Napolitano, Luigi Santini, Department of Anaesthesiologic, Surgical and Emergency Science, VII Division of General Surgery, Second University of Naples, 80131 Naples, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Conzo
authors.affiliation: Giovanni Conzo, Claudio Mauriello, Claudio Gambardella, Fabio Cavallo, Ernesto Tartaglia, Salvatore Napolitano, Luigi Santini, Department of Anaesthesiologic, Surgical and Emergency Science, VII Division of General Surgery, Second University of Naples, 80131 Naples, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Mauriello
authors.affiliation: Giovanni Conzo, Claudio Mauriello, Claudio Gambardella, Fabio Cavallo, Ernesto Tartaglia, Salvatore Napolitano, Luigi Santini, Department of Anaesthesiologic, Surgical and Emergency Science, VII Division of General Surgery, Second University of Naples, 80131 Naples, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Gambardella
authors.affiliation: Giovanni Conzo, Claudio Mauriello, Claudio Gambardella, Fabio Cavallo, Ernesto Tartaglia, Salvatore Napolitano, Luigi Santini, Department of Anaesthesiologic, Surgical and Emergency Science, VII Division of General Surgery, Second University of Naples, 80131 Naples, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Cavallo
authors.affiliation: Giovanni Conzo, Claudio Mauriello, Claudio Gambardella, Fabio Cavallo, Ernesto Tartaglia, Salvatore Napolitano, Luigi Santini, Department of Anaesthesiologic, Surgical and Emergency Science, VII Division of General Surgery, Second University of Naples, 80131 Naples, Italy.
authors.forename: Ernesto
authors.initials: E
authors.lastname: Tartaglia
authors.affiliation: Giovanni Conzo, Claudio Mauriello, Claudio Gambardella, Fabio Cavallo, Ernesto Tartaglia, Salvatore Napolitano, Luigi Santini, Department of Anaesthesiologic, Surgical and Emergency Science, VII Division of General Surgery, Second University of Naples, 80131 Naples, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Napolitano
authors.affiliation: Giovanni Conzo, Claudio Mauriello, Claudio Gambardella, Fabio Cavallo, Ernesto Tartaglia, Salvatore Napolitano, Luigi Santini, Department of Anaesthesiologic, Surgical and Emergency Science, VII Division of General Surgery, Second University of Naples, 80131 Naples, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Santini
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000714:Anastomosis, Surgical; D003082:Colectomy / Q000009:adverse effects / Q000379:methods*; D003113:Colonoscopy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011655:Pulmonary Embolism / Q000209:etiology; D012086:Reoperation; D012811:Sigmoid Neoplasms / Q000473:pathology / Q000601:surgery*; D017792:Surgical Stapling / Q000009:adverse effects; D013997:Time Factors; D016896:Treatment Outcome
keywords: Repeated Anastomotic Recurrence; Stapled Anastomosis; Viable Exfoliated Cells