title: Spectral, morphological and antibacterial studies of β-cyclodextrin stabilized silver - Chitosan nanocomposites.
abstract: The aim of the study is to investigate the antibacterial properties and characterization of β-cyclodextrin (β-CD) stabilized silver - chitosan nanocomposite (Ag-Cts NCs). An effective and eco-friendly technique for the synthesis of Ag-Cts NCs in the presence of a strong stabilizing agent β-CD is described. The well formed nanocomposites were characterized by the Ultraviolet Visible spectroscopy (UV-Vis), X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FT-IR), Photoluminescence spectroscopy (PL), Scanning electron microscope (SEM/EDS), Atomic force microscope (AFM), High resolution transmission electron microscope (HR-TEM) and Zeta potential measurement (ZP). The results confirmed that the poly dispersed Ag-Cts NCs are less than 15nm in size with spherical shape and show good stability. The antibacterial activity was also investigated and β-CD coated Ag-Cts NCs showed a promising bacterial activity against gram negative Escherichia coli (E. coli) and gram positive Staphylococcus aureus (S. aureus) micro-organism.
authors.affiliation: Department of Physics, St. Joseph's College of Engineering, Chennai 600119, India. Electronic address: punithasan@gmail.com.
authors.forename: N
authors.initials: N
authors.lastname: Punitha
authors.affiliation: Department of Physics (DDE Wings), Annamalai University, Annamalai Nagar 608002, India.
authors.forename: P S
authors.initials: PS
authors.lastname: Ramesh
authors.affiliation: Department of Physics, Annamalai University, Annamalai Nagar 608002, India.
authors.forename: D
authors.initials: D
authors.lastname: Geetha
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D048271:Chitosan / Q000737:chemistry / Q000494:pharmacology; D004926:Escherichia coli; D053768:Metal Nanoparticles / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D046529:Microscopy, Electron, Transmission; D053761:Nanocomposites / Q000737:chemistry*; D010316:Particle Size; D012834:Silver / Q000737:chemistry / Q000494:pharmacology; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus; D014961:X-Ray Diffraction; D047392:beta-Cyclodextrins / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D047392:beta-Cyclodextrins; D012834:Silver; D048271:Chitosan
keywords: Antibacterial activity; Biodegradable stabilizer; Silver nanocomposite; Stability