title: Dynamic activation of apoptosis: conformational ensembles of cIAP1 are linked to a spring-loaded mechanism.
authors.affiliation: Structural Biophysics Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.
authors.forename: Michelle L
authors.initials: ML
authors.lastname: Gill
authors.affiliation: Structural Biophysics Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.
authors.forename: R Andrew
authors.initials: RA
authors.lastname: Byrd
mesh_terms: D000818:Animals; D017209:Apoptosis; D055808:Drug Discovery; D006801:Humans; D051034:Inhibitor of Apoptosis Proteins / Q000737:chemistry* / Q000378:metabolism*; D008958:Models, Molecular; D011487:Protein Conformation; D055503:Protein Multimerization; D015398:Signal Transduction; D044767:Ubiquitin-Protein Ligases
chemical_list: D051034:Inhibitor of Apoptosis Proteins; C494833:BIRC2 protein, human; D044767:Ubiquitin-Protein Ligases