title: A facile preparation of glass-supported lipid bilayers for analyzing molecular dynamics.
abstract: Many research programs focus on the molecular dynamics of living cells. This research requires cells to be adhered to a substrate while retaining the innate motility of their surface molecules. Lipid bilayer-based systems fulfill this requirement, although current methods are complicated and their utility is limited. We developed a simple and rapid method for reproducible preparation of homogeneous glass-supported lipid bilayers. Our method provides a facile means for bioimaging and analysis of molecular dynamics in living cells.
authors.affiliation: Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology.
authors.forename: Yuma
authors.initials: Y
authors.lastname: Ito
authors.forename: Kumiko
authors.initials: K
authors.lastname: Sakata-Sogawa
authors.forename: Makio
authors.initials: M
authors.lastname: Tokunaga
mesh_terms: D005898:Glass / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry*; D056004:Molecular Dynamics Simulation
chemical_list: D008051:Lipid Bilayers