title: [The continuum of COPD and cardiovascular risk: A global scenario of disease].
abstract: Chronic obstructive pulmonary disease (COPD) is a serious public health problem in our country. COPD is a treatable and preventable disease which is underdiagnosed. The EPISCAN study revealed a prevalence of 10.2% in Spain between individuals of 40-80 years, with 73% underdiagnosis. In Primary Care occupies 8.5% of all queries with a high economic impact. These patients exhibit some degree of systemic inflammation characterized by increased plasma levels of some inflammatory mediators such as IL-1, IL-6, IL-8, CRP and TNF, which are also related to endothelial disorders and arteriosclerosis. In the continuum of COPD, comorbidities most frequently appear are: ischemic heart disease, heart failure, stroke, hypertension, type 2 diabetes mellitus, renal failure, osteoporosis, myopathy, anxiety, depression, cognitive impairment, malnutrition, anemia and lung cancer.
authors.affiliation: Servicio de Medicina Interna y Medicina de Familia, CAP-Marín EOXI Pontevedra-Salnés, Pontevedra, España. Electronic address: nazara.otero@cmpont.es.
authors.forename: Carlos Alberto
authors.initials: CA
authors.lastname: Názara Otero
authors.affiliation: Servicio de Neumología, CHUP Pontevedra-Salnés, Pontevedra, España.
authors.forename: Adolfo
authors.initials: A
authors.lastname: Baloira Villar
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000503:physiopathology; D006801:Humans; D007249:Inflammation / Q000453:epidemiology* / Q000503:physiopathology; D018836:Inflammation Mediators / Q000097:blood; D008875:Middle Aged; D015995:Prevalence; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology / Q000503:physiopathology*; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
chemical_list: D018836:Inflammation Mediators
keywords: Agudización; COPD; Cardiovascular; Continuo; Continuous; Enfermedad pulmonar obstructiva crónica; Peaking