title: Functionalization of non-activated C-H bonds in the synthesis of vitamin D metabolites and analogs.
abstract: The development of non-microbial methods for the selective functionalization of non-activated C-H bonds has constituted a challenge, with important economical and environmental implications, for chemists for over a century. The present review provides a comprehensive and current compendium that illustrates the power of C-H functionalization and, namely, of remote functionalization strategies, to expeditiously access vitamin D analogs with intricate structures.
authors.affiliation: ProSciens, 2 - 4 rue du Palais de Justice, L-1841 Luxembourg, Luxembourg. moman@prosciens.com.
authors.forename: Edelmiro
authors.initials: E
authors.lastname: Moman
mesh_terms: D000818:Animals; D002384:Catalysis; D006801:Humans; D008958:Models, Molecular; D009930:Organic Chemicals / Q000737:chemistry*; D014807:Vitamin D / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000378:metabolism*
chemical_list: D009930:Organic Chemicals; D014807:Vitamin D