title: Preparation and characterization of collagen-hydroxyapatite/pectin composite.
abstract: Pectin, a kind of plant polysaccharide, was introduced into collagen-hydroxyapatite composite system, and prepared collagen-hydroxyapatite/pectin (Col-HA/pectin) composite in situ. The structure of the composite was investigated by XRD, SEM, and FT-IR. The mechanical properties, water absorption, enzyme degradation, and cytotoxicity of the composite were investigated as well. The results show that the inorganic substance in the composite materials is hydroxyapatite in relatively low crystallinity. A new interface appeared by the interaction among hydroxyapatite and collagen-pectin, and formed smooth fine particles. The mechanical properties, water absorption, enzyme degradation, and cytotoxicity indicate a potential use in bone replacement for the new composite.
authors.affiliation: School of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471003, Henan, China; School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, Henan, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Wenpo
authors.affiliation: School of Medical Technology and Engineering, Henan University of Science and Technology, Luoyang 471003, Henan, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Gaofeng
authors.affiliation: Medical College, Henan University of Science and Technology, Luoyang 471003, Henan, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Shuying
authors.affiliation: School of Life Science, Zhengzhou University, Zhengzhou 450001, Henan, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Yuanming
authors.affiliation: School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, Henan, China. Electronic address: kytang@zzu.edu.cn.
authors.forename: Tang
authors.initials: T
authors.lastname: Keyong
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D018786:Bone Substitutes / Q000737:chemistry; D003094:Collagen / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D008422:Materials Testing; D010368:Pectins / Q000737:chemistry*; D011817:Rabbits; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D010368:Pectins; D003094:Collagen; D017886:Durapatite
keywords: Bone repairing material; Collagen–hydroxyapatite/pectin composite; In situ synthesis