title: [Systemic phlebotrophic agents: from active substance to clinical effect].
abstract: The article deals with the modern classification of phlebotrophic agents, followed by generalization and analysis of their mechanisms of action, peculiarities of their entering the systemic circulation, as well as a detailed description of phlebotrophic properties and clinical application of the water-soluble fraction of flavonoids.
authors.forename: A S
authors.initials: AS
authors.lastname: Dukhanin
mesh_terms: D001682:Biological Availability; D002908:Chronic Disease; D005419:Flavonoids / Q000145:classification / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D020011:Protective Agents / Q000145:classification / Q000493:pharmacokinetics / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome; D014689:Venous Insufficiency / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D005419:Flavonoids; D020011:Protective Agents