title: Dual kidney transplantation involving organs from expanded criteria donors: a review of our series and an update on current indications.
abstract: BACKGROUND
  Our purpose was to review our kidney transplantation program based on the use of expanded criteria donors, and to determine current indications for dual kidney transplantation (DKT). In 1996, a program was initiated to transplant kidneys from donors of over 60 years performing single or dual transplantation.
  
  
  METHODS
  In 1996, a program was initiated to transplant kidneys from donors of over 60 years performing single or dual transplantation. DKT were performed with donors >75 and donors between 60 and 74 years of age and glomerulosclerosis of >15%. The kidneys of donors between 60 and 74 years of age and with glomerulosclerosis of <15% were used for single kidney transplantation (SKT). In 2005, we started to perform SKT despite glomerulosclerosis being >15%, taking into account donor and recipient characteristics.
  
  
  RESULTS
  From 1996 to 2004, 222 SKTs and 88 DKTs were performed. Graft survival after 1 and 4 years was, respectively, 91% and 78% for SKT and 95% and 79% for DKT. In 2005, we started to perform SKT despite glomerulosclerosis being >15%, taking into account donor and recipient characteristics. From 2005 to 2011, 328 SKT and 32 DKT were performed. During this period most kidneys used for DKT were from female donors >75 years old, weighing <65 kg, with a creatinine of >1 mg/dL and glomerulosclerosis of >15%. The recipients for DKT were mostly male, <70 years old and whose weight was >75 kg.
  
  
  CONCLUSIONS
  DKT from expanded criteria donors shows good outcomes. However, in many cases SKT may fulfill the need of the recipient. The archetype for DKT is an older female weighing <65 kg and the most common recipient is an overweight male who is <70 years old.
authors.affiliation: Department of Urology, Hospital Universitario 12 de Octubre, Madrid, Spain. Electronic address: josemedinapolo@movistar.es.
authors.forename: J
authors.initials: J
authors.lastname: Medina-Polo
authors.affiliation: Department of Urology, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Pamplona-Casamayor
authors.affiliation: Department of Urology, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Miranda-Utrera
authors.affiliation: Department of Nephrology and Transplant Coordination, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: E
authors.initials: E
authors.lastname: González-Monte
authors.affiliation: Department of Urology, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: J B
authors.initials: JB
authors.lastname: Passas-Martínez
authors.affiliation: Department of Nephrology and Transplant Coordination, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Andrés Belmonte
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006085:Graft Survival; D006801:Humans; D007674:Kidney Diseases / Q000601:surgery*; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D014019:Tissue Donors