title: Supramolecular solubilization of cyclodextrin-modified carbon nano-onions by host-guest interactions.
abstract: Small carbon nano-onions (CNOs, 6-12 shells) were prepared in high yields and functionalized with carboxylic groups by chemical oxidation and reacted with βCD-NH2 to yield CNOs decorated with βCDs. A biocompatibile dextran polymer with graphted ferrocene groups was employed for the supramolecular self-assembly on the βCD-CNO surfaces. The βCDs act as hosts and the polymer ferrocene groups as guests (Fc-Dex) by the formation of inclusion complexes. After their assembly these nanostructures were soluble in aqueous solutions. The resulting product was characterized by transmission electron microscopy (TEM), thermogravimetric analysis (TGA), and FT-IR and Raman spectroscopies. Moreover, the deposition of successive layers on the surface of the particles was monitored using DLS measurements and zeta potentials. Through-space interactions between the Fc moieties and the CNO cores and the influence of an additional dextran-βCD outer layer were measured electrochemically.
authors.affiliation: Nanobiotechnology & Bioanalysis Group, Departament d'Enginyeria Química, Universitat Rovira i Virgili , Avinguda Països Catalans 26, 43007 Tarragona, Spain.
authors.forename: Ewelina
authors.initials: E
authors.lastname: Wajs
authors.forename: Agustín
authors.initials: A
authors.lastname: Molina-Ontoria
authors.forename: Thorbjørn Terndrup
authors.initials: TT
authors.lastname: Nielsen
authors.forename: Luis
authors.initials: L
authors.lastname: Echegoyen
authors.forename: Alex
authors.initials: A
authors.lastname: Fragoso
mesh_terms: D002244:Carbon / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry; D003505:Cyclodextrins / Q000737:chemistry*; D004563:Electrochemistry; D005296:Ferrous Compounds / Q000737:chemistry; D000075163:Metallocenes; D008958:Models, Molecular; D008968:Molecular Conformation; D049329:Nanostructures / Q000737:chemistry*; D012995:Solubility
chemical_list: D002264:Carboxylic Acids; D003505:Cyclodextrins; D005296:Ferrous Compounds; D000075163:Metallocenes; D002244:Carbon; C004998:ferrocene