title: Parotid gland metastasis from prostate cancer: is docetaxel still the best treatment option?
abstract: Metastases of prostate cancer originating from the parotid gland are rare. However, this presentation raises the question of the management of visceral metastasis in castration-resistant prostate cancer. We report the case of an 87-year-old man who presented with a right painless parotid mass in the context of castration-resistant prostate cancer, indicating progression of the disease. He received medical treatment based on docetaxel. Here, we discuss the impact of new hormonotherapies such as enzalutamide and abiraterone acetate, which may be used for the management of these patients.
authors.affiliation: Departments of aMedical Oncology bRadiology, Hôpital d'Instruction des Armées Val de Grâce cDepartment of Urology, Foch Hospital, Suresnes, Paris dUFR of Health Sciences, Université Versailles-Saint-Quentin-en-Yvelines, Versailles, France.
authors.forename: Carole
authors.initials: C
authors.lastname: Hélissey
authors.forename: Mathieu
authors.initials: M
authors.lastname: Rouanne
authors.forename: Francois-Xavier
authors.initials: FX
authors.lastname: Arnaud
authors.forename: Sylvestre
authors.initials: S
authors.lastname: Le Moulec
mesh_terms: D000069501:Abiraterone Acetate; D000369:Aged, 80 and over; D000736:Androstenes / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides; D000077143:Docetaxel; D006801:Humans; D008297:Male; D009570:Nitriles; D010307:Parotid Neoplasms / Q000188:drug therapy* / Q000556:secondary; D010669:Phenylthiohydantoin / Q000031:analogs & derivatives / Q000627:therapeutic use; D064129:Prostatic Neoplasms, Castration-Resistant / Q000188:drug therapy* / Q000473:pathology; D043823:Taxoids / Q000627:therapeutic use*
chemical_list: D000736:Androstenes; D000970:Antineoplastic Agents; D001549:Benzamides; D009570:Nitriles; D043823:Taxoids; D000077143:Docetaxel; D010669:Phenylthiohydantoin; C540278:enzalutamide; D000069501:Abiraterone Acetate