title: [Structural and functional characteristics of bone tissue and blood cytokines in health and disease of the joints].
abstract: Change of structural and functional state of bone in patients with primary osteoarthrosis of the hip joint compared to healthy individuals is characterized by decreased bone formation with a relative predominance of resorption. Osteopenic syndrome develops in the background of evident imbalance of a blood cytokine profile with increasing the level of proinflammatory and the variability of the level of anti-inflammatory cytokines.
authors.forename: E V
authors.initials: EV
authors.lastname: Kariakina
authors.forename: I A
authors.initials: IA
authors.lastname: Norkin
authors.forename: E V
authors.initials: EV
authors.lastname: Gladkova
authors.forename: E A
authors.initials: EA
authors.lastname: Persova
authors.forename: O V
authors.initials: OV
authors.lastname: Matveeva
authors.forename: D M
authors.initials: DM
authors.lastname: Puchin'ian
mesh_terms: D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood; D015519:Bone Density; D001862:Bone Resorption / Q000097:blood / Q000473:pathology* / Q000503:physiopathology; D001842:Bone and Bones / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D016022:Case-Control Studies; D006621:Hip Joint / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D016753:Interleukin-10 / Q000097:blood; D053583:Interleukin-1beta / Q000097:blood; D015847:Interleukin-4 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000097:blood / Q000473:pathology* / Q000503:physiopathology; D015675:Osteocalcin / Q000097:blood; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
chemical_list: C508609:IL10 protein, human; C508598:IL4 protein, human; C508600:IL6 protein, human; D053583:Interleukin-1beta; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D015675:Osteocalcin; D016753:Interleukin-10; D015847:Interleukin-4; D000469:Alkaline Phosphatase