title: Triterpenoid saponins from root bark of Zanha golungensis (Sapindaceae).
abstract: The chemical investigation of the methanolic extract from root bark of Zanha golungensis Hiern led to the isolation of five new and one known triterpenoid saponins. Their structures were elucidated by full analysis of their spectroscopic data and by partial hydrolysis. These glycosides contain zanhic acid as aglycone, a rare oleanane-type triterpenoid found in species belonging to Sapindaceae, Caryophyllaceae, Asteraceae, and Fabaceae. Two new saponins are esterified saponins by 3,3-dimethylacryloyl and 3-hydroxy-2-methyl-butanoyl residues located on the sugar part. The new compounds were named zanhasaponins D-H following previous isolation of similar compounds from Zanha africana.
authors.affiliation: Institut de Chimie Moléculaire de Reims, CNRS UMR 7312, Université de Reims Champagne-Ardenne, BP 1039, 51687 Reims Cedex 02, France. Electronic address: catherine.lavaud@univ-reims.fr.
authors.forename: Catherine
authors.initials: C
authors.lastname: Lavaud
authors.affiliation: Institut de Chimie Moléculaire de Reims, CNRS UMR 7312, Université de Reims Champagne-Ardenne, BP 1039, 51687 Reims Cedex 02, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Sayagh
authors.affiliation: Institut de Chimie Moléculaire de Reims, CNRS UMR 7312, Université de Reims Champagne-Ardenne, BP 1039, 51687 Reims Cedex 02, France.
authors.forename: Franck
authors.initials: F
authors.lastname: Humbert
authors.affiliation: Epigenetic Targeting of Cancer, CNRS USR 3388, Centre de Recherche et de Développement Pierre Fabre, BP 13562, 31035 Toulouse Cedex 01, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Pouny
authors.affiliation: Institut de Chimie, Université de Liège, B36, Sart Tilman, B-4000 Liège, Belgium.
authors.forename: Clément
authors.initials: C
authors.lastname: Delaude
mesh_terms: D018514:Plant Structures / Q000737:chemistry; D029631:Sapindaceae / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D012503:Saponins; D014315:Triterpenes
keywords: Triterpenoid saponin; Zanha golungensis; Zanhasaponin; Zanhic acid