title: Quantifying the economic benefits of prevention in a healthcare setting with severe financial constraints: the case of hypertension control.
abstract: Hypertension significantly contributes to the increased cardiovascular morbidity and mortality, thus leading to rising healthcare costs. The objective of this study was to quantify the clinical and economic benefits of optimal systolic blood pressure (SBP), in a setting under severe financial constraints, as in the case of Greece. Hence, a Markov model projecting 10-year outcomes and costs was adopted, in order to compare two scenarios. The first one depicted the "current setting", where all hypertensives in Greece presented an average SBP of 164 mmHg, while the second scenario namely "optimal SBP control" represented a hypothesis in which the whole population of hypertensives would achieve optimal SBP (i.e. <140 mmHg). Cardiovascular events' occurrence was estimated for four sub-models (according to gender and smoking status). Costs were calculated from the Greek healthcare system's perspective (discounted at a 3% annual rate). Findings showed that compared to the "current setting", universal "optimal SBP control" could, within a 10-year period, reduce the occurrence of non-fatal events and deaths, by 80 and 61 cases/1000 male smokers; 59 and 37 cases/1000 men non-smokers; whereas the respective figures for women were 69 and 57 cases/1000 women smokers; and accordingly, 52 and 28 cases/1000 women non-smokers. Considering health expenditures, they could be reduced by approximately €83 million per year. Therefore, prevention of cardiovascular events through BP control could result in reduced morbidity, thereby in substantial cost savings. Based on clinical and economic outcomes, interventions that promote BP control should be a health policy priority.
authors.affiliation: Department of Health Economics, National School of Public Health , Athens , Greece and.
authors.forename: Kostas
authors.initials: K
authors.lastname: Athanasakis
authors.forename: Ilias-Ioannis
authors.initials: II
authors.lastname: Kyriopoulos
authors.forename: Nadia
authors.initials: N
authors.lastname: Boubouchairopoulou
authors.forename: George S
authors.initials: GS
authors.lastname: Stergiou
authors.forename: John
authors.initials: J
authors.lastname: Kyriopoulos
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D017046:Cost Savings; D003362:Cost-Benefit Analysis; D005260:Female; D005544:Forecasting; D017048:Health Care Costs / Q000639:trends*; D005102:Health Expenditures; D006801:Humans; D006973:Hypertension / Q000191:economics / Q000453:epidemiology / Q000517:prevention & control*; D015994:Incidence; D008297:Male; D011322:Primary Prevention / Q000191:economics*; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology
keywords: Blood pressure; cost; economic benefits; hypertension; prevention