title: Left ventricular systolic dysfunction in chronic kidney disease: from asymptomatic changes in geometry and function to overt heart failure.
abstract: A bidirectional relationship between kidney and heart function is present in all stages of cardiac and renal disease, from the asymptomatic phase of left ventricular systolic dysfunction to overt heart failure, as well as from the initial reduction of glomerular filtration rate to end-stage kidney disease, respectively. The simultaneous presence of both diseases has a significant impact on prognosis and requires specific therapeutic strategies. The early recognition of abnormalities of renal and myocardial function may have a relevant influence on management of combination of these conditions.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Cioffi
authors.forename: Luigi
authors.initials: L
authors.lastname: Tarantini
authors.forename: Pompilio
authors.initials: P
authors.lastname: Faggiano
authors.forename: Giovanni
authors.initials: G
authors.lastname: Pulignano
authors.forename: Giulia
authors.initials: G
authors.lastname: Russo
authors.forename: Andrea
authors.initials: A
authors.lastname: Di Lenardas
mesh_terms: D002302:Cardiac Output / Q000502:physiology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000503:physiopathology; D003925:Diabetic Angiopathies / Q000503:physiopathology; D003928:Diabetic Nephropathies / Q000503:physiopathology; D006333:Heart Failure / Q000150:complications* / Q000401:mortality / Q000503:physiopathology*; D006801:Humans; D051436:Renal Insufficiency, Chronic / Q000150:complications* / Q000503:physiopathology*; D012307:Risk Factors; D013318:Stroke Volume / Q000502:physiology; D018487:Ventricular Dysfunction, Left / Q000150:complications* / Q000503:physiopathology*