title: [Analysis of the influence of pharmacotherapy on the quality of life of seniors with osteoarthritis].
abstract: OBJECTIVE
  This study aimed to assess the influence of pharmacotherapy on health-related quality of life of elderly with ostheoartritis.
  
  
  METHODS
  Longitudinal study involving 91 older adults from both genders (Age: 70.36±5.57 years) from EELO project with self-reported knee or hip ostheoartritis, confirmed by radiographic analysis. Data regarding pharmacotherapy was assessed by a structured questionnaire and the quality of life was analyzed by SF-36 questionnaire at the initial moment and two years thereafter. All domains from quality of life were grouped in physical and mental components for further data analysis.
  
  
  RESULTS
  A statistically significant decline in health-related quality of life was observed (Wilcoxon test, p<0.05). However, it was observed a slighted decline in physical components in group treated with chondroitin/glucosamine when compared to other groups, according to Kruskal-Wallis test (p=0.007). On the other hand, it was not observed any influence of pharmacological treatment on mental components of health-related quality of life (p>0.05).
  
  
  CONCLUSIONS
  Treatment with condroitin/glucosamin contributes to a lower decline in physical component while it had no influence on mental component of health-related quality of life in older adults with ostheoartritis.
authors.affiliation: Universidade do Norte do Paraná, Londrina, PR, Brasil.
authors.forename: Katia F
authors.initials: KF
authors.lastname: Salvato
authors.affiliation: Universidade do Norte do Paraná, Londrina, PR, Brasil.
authors.forename: João Paulo M
authors.initials: JP
authors.lastname: Santos
authors.affiliation: Universidade do Norte do Paraná, Londrina, PR, Brasil.
authors.forename: Deise A A
authors.initials: DA
authors.lastname: Pires-Oliveira
authors.affiliation: Universidade do Norte do Paraná, Londrina, PR, Brasil.
authors.forename: Viviane S P
authors.initials: VS
authors.lastname: Costa
authors.affiliation: Universidade do Norte do Paraná, Londrina, PR, Brasil.
authors.forename: Mario
authors.initials: M
authors.lastname: Molari
authors.affiliation: Universidade do Norte do Paraná, Londrina, PR, Brasil.
authors.forename: Marcos T P
authors.initials: MT
authors.lastname: Fernandes
authors.affiliation: Universidade do Norte do Paraná, Londrina, PR, Brasil.
authors.forename: Regina C
authors.initials: RC
authors.lastname: Poli-Frederico
authors.affiliation: Universidade do Norte do Paraná, Londrina, PR, Brasil; Pontifícia Universidade Católica do Paraná, Londrina, PR, Brasil. Electronic address: karenparron@gmail.com.
authors.forename: Karen B P
authors.initials: KB
authors.lastname: Fernandes
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D010003:Osteoarthritis / Q000188:drug therapy*; D011788:Quality of Life
keywords: Elderly; Funcionalidade; Functional disability; Functional status; Idoso; Incapacidade funcional; Osteoarthritis; Osteoartrite; Qualidade de vida; Quality of life