title: Comparison of healing effect of aloe vera extract and silver sulfadiazine in burn injuries in experimental rat model.
abstract: BACKGROUND
  Wound healing is widely discussed in the medical literature. This study compared the healing effect of aloe vera extract and silver sulfadiazine in burn injuries in experimental rat model.
  
  
  METHODS
  Sixteen rats were randomly assigned to one of two groups, each group 8 rats. A deep second-degree burn on the lower back and 3(rd) degree burn on upper back of each rat were created with a standard burning procedure. Burns were dressed daily with aloe vera extract in group 2 and silver sulfadiazine in group 1. Response to treatment was assessed by digital photography during treatment until day 32. Histological parameters (PMN, epithelialization, fibrosis and angiogenesis) were assessed after biopsy of scar at the end of research.
  
  
  RESULTS
  Wound healing was more visible in aloe vera group. Also the speed of healing in aloe vera group was better than silver sulfadiazine group.
  
  
  CONCLUSIONS
  Based on our findings, aloe vera can be a therapy of choice for burn injuries.
authors.affiliation: Faculty of Plastic and Reconstructive Surgery, Burn Research Center, Iran University of Medical Sciences, Tehran, Iran;
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Akhoondinasab
authors.affiliation: Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran;
authors.forename: Motahhare
authors.initials: M
authors.lastname: Akhoondinasab
authors.affiliation: Medicine, Quran and Hadith Research Center, Department of Community Medicine, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Saberi
keywords: Aloe vera; Burn; Rat; Silver sulfadiazine