title: Taking charge of siRNA delivery.
abstract: Delivery of siRNA into cells is achieved by neutralizing the negative charge of the phosphate backbone in a reversible manner.
authors.affiliation: RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.
authors.forename: Anastasia
authors.initials: A
authors.lastname: Khvorova
authors.affiliation: RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.
authors.forename: Maire F
authors.initials: MF
authors.lastname: Osborn
authors.affiliation: RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Hassler
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems; D006801:Humans; D011355:Prodrugs / Q000627:therapeutic use*; D034741:RNA, Small Interfering / Q000627:therapeutic use*
chemical_list: D011355:Prodrugs; D034741:RNA, Small Interfering