title: Profile of benign breast diseases in western Saudi Arabia. An 8-year histopathological review of 603 cases.
abstract: OBJECTIVE
  To describe the histopathological patterns of benign breast diseases (BBD) among Saudi patients.
  
  
  METHODS
  This is a retrospective review of BBD reports of Saudi patients of both genders and all age  groups seen between January 2006 and December 2013 at King Fahad Hospital, Madinah, Kingdom of Saudi Arabia.
  
  
  RESULTS
  Out of the total 1005 breast biopsies, 603 cases (60%) were BBD. The female to male ratio was 30.7:1. The overall mean age for BBD was 27.5 years, with an age range of 14-80 years. The most common lesion was fibroadenoma (FA) accounting for 44.3% of cases (mean age: 23.5 years), followed by 23.4% fibrocystic change (FCC) (mean age: 37.1 years). Both lesions had a peak occurrence in the third decade. Inflammatory lesions constituted 13.9% of cases. Most common were granulomatous mastitis (3.5%), chronic mastitis (3.3%), and acute mastitis with abscess (3.1%). Other major lesions encountered were fibroadenomatoid hyperplasia (3.1%), intraductal papilloma (2.8%), and benign phylloides tumor (2.6%). All benign diagnoses in male patients were gynecomastia and most patients (68.4%) were under 40 years.
  
  
  CONCLUSIONS
  In this study, BBD constituted 60% of breast lumps, and were mostly FA and FCC. The BBD peaked at the 20-29 year age range.
authors.affiliation: Department of Pathology, Taibah University, PO Box 344, Madinah, Kingdom of Saudi Arabia. Tel. +966 (14) 8483250. Fax. +966 (14) 8484811. E-mail. abdbasri@hotmail.com.
authors.forename: Abdulkader M
authors.initials: AM
authors.lastname: Albasri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001941:Breast Diseases / Q000453:epidemiology / Q000473:pathology; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D018226:Fibroadenoma / Q000453:epidemiology* / Q000473:pathology; D005348:Fibrocystic Breast Disease / Q000453:epidemiology* / Q000473:pathology; D006177:Gynecomastia / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008413:Mastitis / Q000453:epidemiology* / Q000473:pathology; D008875:Middle Aged; D018300:Papilloma, Intraductal / Q000453:epidemiology / Q000473:pathology; D003557:Phyllodes Tumor / Q000453:epidemiology / Q000473:pathology; D012189:Retrospective Studies; D012529:Saudi Arabia / Q000453:epidemiology; D055815:Young Adult