title: A rare cause of seizures, parkinsonian, and cerebellar signs: brain calcinosis secondary to thyroidectomy.
abstract: BACKGROUND
  Post-thyroidectomy hypoparathyroidism presenting with Parkinsonian features and seizures with extensive intracranial calcifications is uncommon. Acquired intracranial calcification that affects structures other than the basal ganglia is rare.
  
  
  METHODS
  We report a case of a 45-year-old woman with a history of total thyroidectomy who presented with Parkinsonian features, cerebellar signs, and seizures. Brain imaging revealed extensive intracranial calcifications secondary to long-standing hypoparathyroidism. The patient was treated with intravenous (IV) calcium gluconate therapy and shifted to oral calcium and calcitriol therapy. Her symptoms improved markedly. At four months of follow up, the patient had not suffered another episode of seizure and was being gradually weaned off anti-Parkinsonian therapy.
  
  
  CONCLUSIONS
  This case describes the rare finding of extensive intracranial calcifications in a case of iatrogenic hypoparathyroidism secondary to thyroidectomy with its wide array of features and its remarkable response to restoration of calcium levels to normal limits.
authors.affiliation: Department of General Medicine, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, West Bengal, India.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Agarwal
authors.affiliation: Department of General Medicine, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, West Bengal, India.
authors.forename: Durjoy
authors.initials: D
authors.lastname: Lahiri
authors.affiliation: Department of General Medicine, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, West Bengal, India.
authors.forename: Amrita
authors.initials: A
authors.lastname: Biswas
authors.affiliation: Department of General Medicine, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, West Bengal, India.
authors.forename: Jotideb
authors.initials: J
authors.lastname: Mukhopadhyay
authors.affiliation: Department of General Medicine, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, West Bengal, India.
authors.forename: Pranab
authors.initials: P
authors.lastname: Maity
authors.affiliation: Department of General Medicine, Institute of Post-Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial Hospital, Kolkata, West Bengal, India.
authors.forename: Manoj Kumar
authors.initials: MK
authors.lastname: Roy
keywords: Cerebellar and parkinsonian features after thyroidectomy; Hypoparathyroidism leading to seizures; Parkinsonism secondary to thyroidectomy