title: Treatment of resistant epilepsy.
abstract: Treatment resistance affects around 20% of people with epilepsy and carries a significant comorbidity. It is important to ensure that the diagnosis of epilepsy is secure and the underlying cause of the epilepsy is investigated thoroughly. Management involves early referral for epilepsy surgery when suitable, optimisation of pharmacological treatment, and consideration of comorbidities such as depression.
authors.affiliation: Neurology and Molecular Neuroscience Research Group, College of Medicine, Swansea University, Swansea, UK, and Welsh Epilepsy Centre, University Hospital of Wales, Cardiff, UK.
authors.forename: William Owen
authors.initials: WO
authors.lastname: Pickrell
authors.affiliation: Wales Epilepsy Centre, University Hospital of Wales, Cardiff, UK smithpe@cardiff.ac.uk.
authors.forename: Phil E M
authors.initials: PE
authors.lastname: Smith
mesh_terms: D055423:Diet, Ketogenic; D000069279:Drug Resistant Epilepsy / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D009493:Neurosurgery
keywords: Epilepsy; management; treatment resistance