title: Evaluation of fluid status related parameters in hemodialysis and peritoneal dialysis patients: Clinical usefulness of bioimpedance analysis.
abstract: OBJECTIVE
  Fluid overload is a common and serious problem that leads to severe complications in dialysis patients. We aimed to compare hydration status as measured with bioimpedance analysis (BIA) method in hemodialysis (HD) and peritoneal dialysis (PD) patients, as well as investigating the association between blood pressure, left ventricular mass index (LVMI) and hydration status.
  
  
  METHODS
  We examined 43 HD and 33 PD patients. Blood pressure was recorded. In each group, echocardiographic examinations were performed on all patients. Hydration status was assessed using multifrequency bioelectrical impedance analysis. Overhydration was defined as an overhydration (OH)/extracellular water (ECW) ratio of >0.15.
  
  
  RESULTS
  The OH/ECW ratio was significantly higher in PD patients compared to post-HD patients. Overhydration was statistically more frequent in PD than in post-HD patients (30.3% vs. 11.6%, P=0.043). Systolic blood pressure (SBP) in both post-HD and PD groups, and LVMI in the PD group were found to be significantly higher in overhydrated patients than non-overhydrated patients. In multiple linear regression analyses, increased OH/ECW ratio was independently associated with higher SBP and LVMI.
  
  
  CONCLUSIONS
  Fluid overload may be an even more prevalent and serious problem in PD patients. Overhydration is closely associated with increased blood pressure and LVMI. OH/ECW ratio, a derived parameter of fluid load measured by BIA, was a significant and independent determinant of SBP and LVMI.
authors.affiliation: Department of Nephrology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey. Electronic address: drzulf21@gmail.com.
authors.forename: Zülfükar
authors.initials: Z
authors.lastname: Yılmaz
authors.affiliation: Department of Nephrology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: Yaşar
authors.initials: Y
authors.lastname: Yıldırım
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: Fatma Yılmaz
authors.initials: FY
authors.lastname: Aydın
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Aydın
authors.affiliation: Department of Nephrology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: Ali Kemal
authors.initials: AK
authors.lastname: Kadiroğlu
authors.affiliation: Department of Nephrology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: Mehmet Emin
authors.initials: ME
authors.lastname: Yılmaz
authors.affiliation: Department of Cardiology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: Halit
authors.initials: H
authors.lastname: Acet
mesh_terms: D000328:Adult; D001794:Blood Pressure; D001795:Blood Pressure Determination; D003430:Cross-Sectional Studies; D004452:Echocardiography; D017097:Electric Impedance; D045604:Extracellular Fluid; D005260:Female; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000009:adverse effects; D006435:Renal Dialysis / Q000009:adverse effects*
keywords: Bioimpedance analysis; Hemodialysis; Peritoneal dialysis