title: Repetitive behavior in Rubinstein-Taybi syndrome: parallels with autism spectrum phenomenology.
abstract: Syndrome specific repetitive behavior profiles have been described previously. A detailed profile is absent for Rubinstein-Taybi syndrome (RTS). The Repetitive Behaviour Questionnaire and Social Communication Questionnaire were completed for children and adults with RTS (N = 87), Fragile-X (N = 196) and Down (N = 132) syndromes, and individuals reaching cut-off for autism spectrum disorder (N = 228). Total and matched group analyses were conducted. A phenotypic profile of repetitive behavior was found in RTS. The majority of behaviors in RTS were not associated with social-communication deficits or degree of disability. Repetitive behavior should be studied at a fine-grained level. A dissociation of the triad of impairments might be evident in RTS.
authors.affiliation: Cerebra Centre for Neurodevelopmental Disorders, School of Psychology, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK, j.e.waite@bham.ac.uk.
authors.forename: Jane
authors.initials: J
authors.lastname: Waite
authors.forename: Joanna
authors.initials: J
authors.lastname: Moss
authors.forename: Sarah R
authors.initials: SR
authors.lastname: Beck
authors.forename: Caroline
authors.initials: C
authors.lastname: Richards
authors.forename: Lisa
authors.initials: L
authors.lastname: Nelson
authors.forename: Kate
authors.initials: K
authors.lastname: Arron
authors.forename: Cheryl
authors.initials: C
authors.lastname: Burbidge
authors.forename: Katy
authors.initials: K
authors.lastname: Berg
authors.forename: Chris
authors.initials: C
authors.lastname: Oliver
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000150:complications / Q000175:diagnosis*; D002675:Child, Preschool; D003147:Communication Disorders / Q000150:complications / Q000175:diagnosis; D003192:Compulsive Behavior / Q000150:complications / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D004314:Down Syndrome / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005600:Fragile X Syndrome / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012415:Rubinstein-Taybi Syndrome / Q000150:complications / Q000175:diagnosis*; D063189:Symptom Assessment; D055815:Young Adult