title: CaCO₃ vaterite microparticles for biomedical and personal care applications.
abstract: Among the polymorph modifications of calcium carbonate, the metastable vaterite is the most practically important. Vaterite particles are applied in regenerative medicine, drug delivery and a broad range of personal care products. This manuscript scopes to review the mechanism of the calcium carbonate crystal growth highlighting the factors stabilizing the vaterite polymorph in the most cost efficient synthesis routine. The size of vaterite particles is a crucial parameter for practical applications. The options for tuning the particle size are also discussed.
authors.affiliation: Institute of Materials Research and Engineering, A*STAR, Singapore 117602, Singapore; Lomonosov Moscow State University, Faculty of Physics, Moscow 119991, Russia.
authors.forename: Daria B
authors.initials: DB
authors.lastname: Trushina
authors.affiliation: National Research Centre "Kurchatov Institute", Moscow 123098, Russia; A.V. Shubnikov Institute of Crystallography, Moscow 119333, Russia.
authors.forename: Tatiana V
authors.initials: TV
authors.lastname: Bukreeva
authors.affiliation: National Research Centre "Kurchatov Institute", Moscow 123098, Russia; A.V. Shubnikov Institute of Crystallography, Moscow 119333, Russia.
authors.forename: Mikhail V
authors.initials: MV
authors.lastname: Kovalchuk
authors.affiliation: Institute of Materials Research and Engineering, A*STAR, Singapore 117602, Singapore. Electronic address: antipinam@imre.a-star.edu.sg.
authors.forename: Maria N
authors.initials: MN
authors.lastname: Antipina
mesh_terms: D000438:Alcohols / Q000737:chemistry; D001419:Bacteria / Q000737:chemistry; D002119:Calcium Carbonate / Q000737:chemistry*; D003460:Crystallization; D050091:Dendrimers / Q000737:chemistry; D010316:Particle Size; D011108:Polymers / Q000737:chemistry; D016062:Porosity; D011506:Proteins / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000438:Alcohols; D050091:Dendrimers; D011108:Polymers; D011506:Proteins; D002119:Calcium Carbonate
keywords: Biomineral; Calcium carbonate (CaCO(3)); Co-precipitation; Crystal growth; Vaterite polymorph