title: High prevalence of measles seronegativity in adults with HIV infection born in the era of measles vaccination in Northern France.
abstract: We investigated measles humoral immunity levels in a cohort of HIV-infected adult patients in France and attempted to identify risk factors for antimeasles antibodies seronegativity. Being born after 1983 [odds ratio (OR) 4.40; 95% confidence interval (95% CI) 1.26-14.09; P = 0.0013] and a nadir CD4⁺ cell count below 100 cells/μl (OR 4.79; 95% CI 1.61-14.82; P = 0.0048) were the two factors independently associated with measles seronegativity. Systematic measles antibody screening should be performed in HIV-infected individuals born in the era of measles vaccination (after 1983 in France).
authors.affiliation: aCHU Reims, Hôpital Robert Debré, Unité des Maladies Infectieuses et Tropicales bUniversité de Reims Champagne-Ardenne, Faculté de médecine, EA 3797 cCHU Reims, Hôpital Robert Debré, Pôle Recherche et Innovations, Unité d'aide méthodologique dCHU Reims, Hôpital Robert Debré, Laboratoire de Virologie Médicale et Moléculaire eUniversité de Reims Champagne-Ardenne, Faculté de médecine, EA-4684/SFR CAP-SANTE, Reims, France.
authors.forename: Dorothee
authors.initials: D
authors.lastname: Lambert
authors.forename: Moustapha
authors.initials: M
authors.lastname: Dramé
authors.forename: Christine
authors.initials: C
authors.lastname: Rouger
authors.forename: Veronique
authors.initials: V
authors.lastname: Brodard
authors.forename: Yohan
authors.initials: Y
authors.lastname: Nguyen
authors.forename: Jean Luc
authors.initials: JL
authors.lastname: Berger
authors.forename: Isabelle
authors.initials: I
authors.lastname: Kmiec
authors.forename: Maxime
authors.initials: M
authors.lastname: Hentzien
authors.forename: Delphine
authors.initials: D
authors.lastname: Lebrun
authors.forename: Roland
authors.initials: R
authors.lastname: Jaussaud
authors.forename: Laurent
authors.initials: L
authors.lastname: Andreoletti
authors.forename: Firouzé
authors.initials: F
authors.lastname: Bani-Sadr
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D018791:CD4 Lymphocyte Count; D005260:Female; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000453:epidemiology*; D015497:HIV-1; D006801:Humans; D056724:Immunity, Humoral; D008297:Male; D008457:Measles / Q000453:epidemiology*; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D012307:Risk Factors; D014611:Vaccination / Q000706:statistics & numerical data*
chemical_list: D000914:Antibodies, Viral