title: The role of transperineal template biopsies of the prostate in the diagnosis of prostate cancer: a review.
abstract: The incidence of prostate cancer has shown a significant increase, highlighting the importance of early diagnosis. Current practice considers histological diagnosis a necessity in the majority of the cases. The limitations of transrectal biopsies led to the development of the promising transperineal prostatic biopsies. The latter offers a safer approach by avoiding the rectum, utilizing brachytherapy template grid to detect anterior zone disease and provides accurate prostatic mapping by systematically sampling the whole gland. It also helps to direct biopsies based on images obtained from previous prostate scanning and identify those eligible for focal therapy to direct focal treatment accurately. The current literature provides enough reassurance that transperineal template biopsies are effective, efficient and superior to the traditional and inaccurate transrectal biopsies. The absence of consensus on the technical aspect of template biopsies is a drawback, yet it highlights the need to develop robust guidelines to standardize the procedure.
authors.affiliation: Wrexham Maelor Hospital, Croesnewydd Road, Wrexham, Wales, LL13 7TD, UK.
authors.forename: Mohamed Ismat
authors.initials: MI
authors.lastname: Abdulmajed
authors.forename: Daniel
authors.initials: D
authors.lastname: Hughes
authors.forename: Iqbal Singh
authors.initials: IS
authors.lastname: Shergill
mesh_terms: D019072:Antibiotic Prophylaxis; D001706:Biopsy; D006801:Humans; D061705:Image-Guided Biopsy; D008297:Male; D010502:Perineum / Q000473:pathology*; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology*
keywords: brachytherapy template grid; prostate cancer; prostate mapping; transperineal template biopsies; transrectal ultrasound