title: TNF inhibitors directly target Th17 cells via attenuation of autonomous TNF/TNFR2 signalling in psoriasis.
authors.affiliation: Department of Dermatology, Kochi Medical School, Kochi University, Nankoku, Japan.
authors.forename: Takeo
authors.initials: T
authors.lastname: Shiga
authors.affiliation: Department of Dermatology, Kochi Medical School, Kochi University, Nankoku, Japan; Pharmacology Department, Drug Research Center, Kaken Pharmaceutical Co., Ltd., Kyoto, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Sato
authors.affiliation: Science Research Center, Kochi University, Nankoku, Japan.
authors.forename: Sayo
authors.initials: S
authors.lastname: Kataoka
authors.affiliation: Department of Dermatology, Kochi Medical School, Kochi University, Nankoku, Japan. Electronic address: sano.derma@kochi-u.ac.jp.
authors.forename: Shigetoshi
authors.initials: S
authors.lastname: Sano
mesh_terms: D000911:Antibodies, Monoclonal / Q000737:chemistry; D002454:Cell Differentiation; D002460:Cell Line; D049109:Cell Proliferation; D016207:Cytokines / Q000378:metabolism; D003713:Dendritic Cells / Q000166:cytology; D015536:Down-Regulation; D006801:Humans; D007249:Inflammation; D020381:Interleukin-17 / Q000378:metabolism; D007963:Leukocytes, Mononuclear / Q000166:cytology; D011565:Psoriasis / Q000378:metabolism; D047889:Receptors, Tumor Necrosis Factor, Type II / Q000378:metabolism*; D015398:Signal Transduction; D058504:Th17 Cells / Q000166:cytology*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D000911:Antibodies, Monoclonal; D016207:Cytokines; D020381:Interleukin-17; D047889:Receptors, Tumor Necrosis Factor, Type II; D014409:Tumor Necrosis Factor-alpha