title: Non surgical treatment of vestibular schwannoma.
abstract: OBJECTIVE
  To evaluate the results of local control and complications in the treatment of vestibular schwannoma treated with radiation.
  
  
  METHODS
  A retrospective study of 194 patients diagnosed with vestibular schwannoma, treated consecutively with radiation (either stereotactic radiosurgery or fractionated radiotherapy) from 1997 to 2012. We analyze the local control of tumors, as well as secondary complications to treatment with radiation.
  
  
  RESULTS
  A total of 132 (68%) tumors 68% are grade I-II tumors of the Koos classification, 40 (19%) are grade III, and 22 (13%) are grade IV. The tumors associated with neurofibromatosis (NF2), are 3.6% (6 tumors in 4 patients). The tumor control for the overall serie is 97% at 5 years, with a median follow-up of 80.4 months. For large tumors the local control is 91% at 5 years. Free survival of chronic complications is 89% at 5 years. Additionally, 50 tumors were subjected to regular follow-up with MRI without treatment, and 28 (58%) did not experienced tumor growth.
  
  
  CONCLUSIONS
  Radiation and follow up with MRI, are an alternative to surgery in the treatment of vestibular schwannoma, with a low level of complications inside of multidisciplinary approach.
authors.affiliation: Servicio de Oncología Radioterápica, Hospital Fundación IVO, Valencia, España; Facultad de Medicina, Universidad Católica de Valencia San Vicente Mártir, Valencia, España. Electronic address: larribas@fivo.org.
authors.forename: Leoncio
authors.initials: L
authors.lastname: Arribas
authors.affiliation: Servicio de Oncología Radioterápica, Hospital Fundación IVO, Valencia, España.
authors.forename: María L
authors.initials: ML
authors.lastname: Chust
authors.affiliation: Servicio de Neurocirugía, Hospital Universitario La Fé, Valencia, España.
authors.forename: Antonio
authors.initials: A
authors.lastname: Menéndez
authors.affiliation: Servicio de Radiología, Hospital Fundación IVO, Valencia, España.
authors.forename: Estanislao
authors.initials: E
authors.lastname: Arana
authors.affiliation: Servicio de ORL, Hospital Fundación IVO, Valencia, España.
authors.forename: Juan B
authors.initials: JB
authors.lastname: Vendrell
authors.affiliation: Servicio de Radiofísica, Hospital Fundación IVO, Valencia, España.
authors.forename: Vicente
authors.initials: V
authors.lastname: Crispín
authors.affiliation: Servicio de Oncología Radioterápica, Hospital Fundación IVO, Valencia, España.
authors.forename: Carmen
authors.initials: C
authors.lastname: Pesudo
authors.affiliation: Servicio de Oncología Radioterápica, Hospital Fundación IVO, Valencia, España.
authors.forename: José L
authors.initials: JL
authors.lastname: Mengual
authors.affiliation: Servicio de Oncología Radioterápica, Hospital Fundación IVO, Valencia, España.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Mut
authors.affiliation: Servicio de ORL, Hospital General de Valencia, Valencia, España.
authors.forename: Mar
authors.initials: M
authors.lastname: Arribas
authors.affiliation: Servicio de Oncología Radioterápica, Hospital Fundación IVO, Valencia, España.
authors.forename: José L
authors.initials: JL
authors.lastname: Guinot
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003389:Cranial Nerve Diseases / Q000209:etiology; D019583:Dose Fractionation, Radiation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D016518:Neurofibromatosis 2; D009464:Neuroma, Acoustic / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000209:etiology; D016634:Radiosurgery / Q000009:adverse effects; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
keywords: Acoustic neuroma; Fractionated stereotactic radiotherapy; Neurinoma acústico; Observación; Observation; Radiocirugía; Radiosurgery; Radioterapia estereotáctica fraccionada; Schwannoma vestibular; Vestibular schwannoma