title: Drug resistance profiles and clonality of sporadic Shigella sonnei isolates in Ankara, Turkey.
abstract: The aims of this study were to investigate drug resistance rates, types of extended spectrum beta lactamases (ESBLs), and molecular epidemiological characteristics of 43 Shigella sonnei isolates. Ampicillin-sulbactam, amoxicillin-clavulanate, chloramphenicol, and ciprofloxacin were the most active antibiotics. Five isolates harbored bla SHV-12, bla(TEM-1) and bla(CTX-M-15). More than 90% of the isolates had an indistinguishable pulsotype.
authors.affiliation: Central Microbiology Laboratory Medical Faculty Gazi University Ankara Turkey Central Microbiology Laboratory, Medical Faculty, Gazi University, Ankara, Turkey.
authors.forename: Birgul
authors.initials: B
authors.lastname: Kacmaz
authors.affiliation: Molecular Microbiology Research and Application Laboratory National Public Health Agency Ankara Turkey Molecular Microbiology Research and Application Laboratory, National Public Health Agency, Ankara, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Unaldi
authors.affiliation: Department of Clinical Microbiology Medical Faculty Gazi University Ankara Turkey Department of Clinical Microbiology, Medical Faculty, Gazi University, Ankara, Turkey.
authors.forename: Nedim
authors.initials: N
authors.lastname: Sultan
authors.affiliation: Molecular Microbiology Research and Application Laboratory National Public Health Agency Ankara Turkey Molecular Microbiology Research and Application Laboratory, National Public Health Agency, Ankara, Turkey. ; Department of Clinical Microbiology Medical Faculty Kirikkale University Kirikkale Turkey Department of Clinical Microbiology, Medical Faculty, Kirikkale University, Kirikkale, Turkey.
authors.forename: Riza
authors.initials: R
authors.lastname: Durmaz
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D004405:Dysentery, Bacillary / Q000453:epidemiology / Q000382:microbiology*; D005838:Genotype; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D058889:Molecular Typing; D012764:Shigella sonnei / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D014421:Turkey / Q000453:epidemiology; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases
keywords: Shigella sonnei; extended spectrum beta-lactamase; plasmid profile; pulsed-field gel electrophoresis