title: A highly selective fluorescent 'turn-on' chemosensor for Zn(2+) based on a benzothiazole conjugate: their applicability in live cell imaging and use of the resultant complex as a secondary sensor of CN(-).
abstract: A benzothiazole derivative linked "off-on" multi-responsive and selective chemosensor has been synthesized and evaluated for cation recognition properties. The receptor shows a high sensitivity and selectivity for Zn(2+) through a 'turn-on' fluorescence response over the other tested cations with a detection limit as low as 0.67 μM. The receptor was successfully applied for the detection of Zn(2+) in live HeLa cells. Then, the Zn(2+) complex of receptor was also used for cyanide detection and recognition.
authors.affiliation: School of Chemical Sciences, North Maharashtra University, Jalgaon-425001, MS, India. kuwaras@gmail.com.
authors.forename: Nilesh
authors.initials: N
authors.lastname: Khairnar
authors.forename: Kundan
authors.initials: K
authors.lastname: Tayade
authors.forename: Suban K
authors.initials: SK
authors.lastname: Sahoo
authors.forename: Banashree
authors.initials: B
authors.lastname: Bondhopadhyay
authors.forename: Anupam
authors.initials: A
authors.lastname: Basu
authors.forename: Jasminder
authors.initials: J
authors.lastname: Singh
authors.forename: Narinder
authors.initials: N
authors.lastname: Singh
authors.forename: Vikas
authors.initials: V
authors.lastname: Gite
authors.forename: Anil
authors.initials: A
authors.lastname: Kuwar
mesh_terms: D052160:Benzothiazoles / Q000737:chemistry*; D002470:Cell Survival; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D004121:Dimethyl Sulfoxide / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D057230:Limit of Detection; D008958:Models, Molecular; D008968:Molecular Conformation; D057054:Molecular Imaging; D009570:Nitriles / Q000032:analysis* / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D014867:Water / Q000737:chemistry; D015032:Zinc / Q000032:analysis* / Q000737:chemistry
chemical_list: D052160:Benzothiazoles; D005456:Fluorescent Dyes; D009570:Nitriles; D014867:Water; C005465:benzothiazole; D015032:Zinc; D004121:Dimethyl Sulfoxide