title: Shedding light on the chloroplast as a remote control of nuclear gene expression.
abstract: Plants rely on a sophisticated light sensing and signaling system that allows them to respond to environmental changes. Photosensory protein systems -phytochromes, cryptochromes, phototropins, and ultraviolet (UV)-B photoreceptors- have evolved to let plants monitor light conditions and regulate different levels of gene expression and developmental processes. However, even though photoreceptor proteins are best characterized and deeply studied, it is also known that chloroplasts are able to sense light conditions and communicate the variations to the nucleus that adjust its transcriptome to the changing environment. The redox state of components of the photosynthetic electron transport chain works as a sensor of photosynthetic activity and can affect nuclear gene expression by a retrograde signaling pathway. Recently, our groups showed that a retrograde signaling pathway can modulate the alternative splicing process, revealing a novel layer of gene expression control by chloroplast retrograde signaling.
authors.affiliation: a Laboratorio de Fisiología y Biología Molecular; Departamento de Fisiología, Biología Molecular y Celular; IFIBYNE-CONICET; Facultad de Ciencias Exactas y Naturales ; Universidad de Buenos Aires; Ciudad Universitaria ; Buenos Aires , Argentina.
authors.forename: Micaela A
authors.initials: MA
authors.lastname: Godoy Herz
authors.forename: Alberto R
authors.initials: AR
authors.lastname: Kornblihtt
authors.forename: Andrea
authors.initials: A
authors.lastname: Barta
authors.forename: Maria
authors.initials: M
authors.lastname: Kalyna
authors.forename: Ezequiel
authors.initials: E
authors.lastname: Petrillo
mesh_terms: D002467:Cell Nucleus / Q000235:genetics* / Q000528:radiation effects; D002736:Chloroplasts / Q000235:genetics* / Q000528:radiation effects; D018506:Gene Expression Regulation, Plant / Q000528:radiation effects*; D008027:Light; D055537:Light Signal Transduction / Q000235:genetics / Q000528:radiation effects; D055519:Photoreceptors, Plant / Q000235:genetics / Q000378:metabolism
chemical_list: D055519:Photoreceptors, Plant
keywords: RNA; alternative splicing; chloroplast; light; retrograde signal