title: [Levodopa: the story continues].
abstract: The history of development of the drug levodopa is described. It is emphasized that the conception of continuous dopaminergic stimulation in treatment of Parkinson's disease is of great importance. Special attention is drawn to the studies on efficacy and safety of levodopa-carbidopa intestinal gel, quality of life of patients treated with this drug as well as to the experience of long-term treatment.
authors.forename: N V
authors.initials: NV
authors.lastname: Titova
authors.forename: E A
authors.initials: EA
authors.lastname: Katunina
mesh_terms: D000978:Antiparkinson Agents / Q000009:adverse effects / Q000737:chemistry / Q000627:therapeutic use; D002230:Carbidopa / Q000009:adverse effects / Q000737:chemistry / Q000627:therapeutic use; D006801:Humans; D007980:Levodopa / Q000009:adverse effects / Q000737:chemistry / Q000627:therapeutic use; D008297:Male; D010300:Parkinson Disease / Q000188:drug therapy*
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa; D002230:Carbidopa