title: Experimental studies on the biological effects of extracorporeal shock wave therapy on tendon models. A review of the literature.
abstract: Encouraging results using extracorporeal shock wave therapy (ESWT) for treating chronic tendinopathies were recently obtained, although the specific mechanisms by which it induces therapeutic effects remain largely unknown. In order to provide possible explications of such clinical efficacy, several reports have investigated the effects of ESWT on animal models and different kind of cultured cells. Our contribute in establishing the potential outcome of ESWT on human primary cultured tenocytes, derived from healthy compared to ruptured tendons, have supported the growing evidence that shock waves may supply faster post-injury recovery. The purpose of this review was to summarize and evaluate the available basic scientific evidences for using ESWT in tendon pathologies, suggesting possible shock waves-induced mechanisms of tissue repair.
authors.affiliation: Department of Clinical and Molecular Medicine, "Sapienza" University of Rome, Italy; Sant'Andrea Hospital, Rome, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Visco
authors.affiliation: Department of Ortophaedics and Traumatology, "Sapienza" University of Rome, Italy; Sant'Andrea Hospital, Rome, Italy.
authors.forename: Maria Chiara
authors.initials: MC
authors.lastname: Vulpiani
authors.affiliation: Department of Clinical and Molecular Medicine, "Sapienza" University of Rome, Italy; Sant'Andrea Hospital, Rome, Italy.
authors.forename: Maria Rosaria
authors.initials: MR
authors.lastname: Torrisi
authors.affiliation: Department of Ortophaedics and Traumatology, "Sapienza" University of Rome, Italy; Sant'Andrea Hospital, Rome, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Ferretti
authors.affiliation: Department of Clinical and Molecular Medicine, "Sapienza" University of Rome, Italy; Sant'Andrea Hospital, Rome, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Pavan
authors.affiliation: Department of Ortophaedics and Traumatology, "Sapienza" University of Rome, Italy; Sant'Andrea Hospital, Rome, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Vetrano
keywords: ESWT; extracorporeal shock wave therapy; tendon