title: Neurotrophic keratopathy due to dorsolateral medullary infarction (Wallenberg syndrome): case report and literature review.
abstract: BACKGROUND
  Dorsolateral medullary infarction (Wallenberg syndrome) is rare in clinical practice; however, the subsequent corneal lesions are more uncommon. To our knowledge, only one such case was previously reported. We report a similar case with successful treatment and recovery, and analyse both cases to address the clinical features and outcomes of such syndrome.
  
  
  METHODS
  A 43-year-old male presented with neurotrophic keratopathy one month after sustaining dorsolateral medullary infarction. The patient underwent amniotic membrane transplantation twice. Two-year follow-up observation revealed changes in nerve fibers and epithelial cells of corneal by laser confocal microscopy.
  
  
  CONCLUSIONS
  By studying both cases, we confirm that neurotrophic keratopathy could be as a delayed-onset complication of Wallenberg syndrome. The recognition that neurotrophic keratopathy can follow dorsolateral medullary infarction could prevent the clinical misdiagnosis.
authors.affiliation: Department of Neurology, First Hospital of Xi'an, Xi'an 710002, Shaanxi, China. wusongdi@gmail.com.
authors.forename: Songdi
authors.initials: S
authors.lastname: Wu
authors.forename: Ningning
authors.initials: N
authors.lastname: Li
authors.forename: Feng
authors.initials: F
authors.lastname: Xia
authors.forename: Kastytis
authors.initials: K
authors.lastname: Sidlauskas
authors.forename: Xuemei
authors.initials: X
authors.lastname: Lin
authors.forename: Yihua
authors.initials: Y
authors.lastname: Qian
authors.forename: Wei
authors.initials: W
authors.lastname: Gao
authors.forename: Qinlu
authors.initials: Q
authors.lastname: Zhang
mesh_terms: D000328:Adult; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology*; D019573:Epithelium, Corneal / Q000294:innervation / Q000473:pathology*; D006801:Humans; D014854:Lateral Medullary Syndrome / Q000150:complications*; D008297:Male; D009412:Nerve Fibers / Q000473:pathology