title: [Post-traumatic mucormycosis due to Lichtheimia corymbifera: three case reports].
abstract: We report 3 cases of post-traumatic cutaneous mucormycosis caused by Lichtheimia corymbifera, two of them occurring after a farm working accident. Management of post-traumatic mucormycoses consists of a wide excision of the infected tissue, combined with immediate antifungal therapy. Liposomal amphotericin B is the recommended first line treatment. Few studies have evaluated the efficacy of posaconazole. All 3 patients received a surgical debridement and liposomal amphotericin B, which was followed by posaconazole in 2 cases. The duration of the antifungal treatment is not yet well defined. All three patients received a treatment of five weeks with a favorable outcome.
authors.affiliation: Unité de médecine interne et des maladies infectieuses et tropicales, CHU de Reims, 51092 Reims cedex, France.
authors.forename: D
authors.initials: D
authors.lastname: Lambert
authors.affiliation: Service de chirurgie orthopédique et traumatologique, CHU de Reims, 51092 Reims, France.
authors.forename: C
authors.initials: C
authors.lastname: Nerot
authors.affiliation: Laboratoire de parasitologie-mycologie, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Huguenin
authors.affiliation: Service de chirurgie orthopédique et traumatologique, CHU de Reims, 51092 Reims, France.
authors.forename: S
authors.initials: S
authors.lastname: Diallo
authors.affiliation: Laboratoire de parasitologie-mycologie, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France; EA 3800, université Reims Champagne-Ardenne, 51096 Reims cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Mzabi
authors.affiliation: Service de chirurgie orthopédique et traumatologique, CHU de Reims, 51092 Reims, France.
authors.forename: X
authors.initials: X
authors.lastname: Ohl
authors.affiliation: Unité de médecine interne et des maladies infectieuses et tropicales, CHU de Reims, 51092 Reims cedex, France.
authors.forename: V
authors.initials: V
authors.lastname: Noel
authors.affiliation: Unité de médecine interne et des maladies infectieuses et tropicales, CHU de Reims, 51092 Reims cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Rouger
authors.affiliation: Unité de médecine interne et des maladies infectieuses et tropicales, CHU de Reims, 51092 Reims cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Strady
authors.affiliation: Laboratoire de parasitologie-mycologie, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France; EA 3800, université Reims Champagne-Ardenne, 51096 Reims cedex, France.
authors.forename: I
authors.initials: I
authors.lastname: Villena
authors.affiliation: Unité de médecine interne et des maladies infectieuses et tropicales, CHU de Reims, 51092 Reims cedex, France; EA-4684, université Reims Champagne-Ardenne, 51096 Reims cedex, France.
authors.forename: F
authors.initials: F
authors.lastname: Bani-Sadr
authors.affiliation: Laboratoire de parasitologie-mycologie, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France; Unité MEDyC, CNRS UMR7369, université Reims Champagne-Ardenne, 51096 Reims cedex, France. Electronic address: dtoubas@chu-reims.fr.
authors.forename: D
authors.initials: D
authors.lastname: Toubas
mesh_terms: D020095:Absidia / Q000302:isolation & purification*; D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D003646:Debridement; D003881:Dermatomycoses / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D014947:Wounds and Injuries / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery
chemical_list: D000935:Antifungal Agents
keywords: Cutaneous mucormycosis; Lichtheimia corymbifera; Mucormycoses; Mucormycoses cutanées; Mucormycoses post-traumatiques; Mucormycosis; Posaconazole; Post-traumatic mucormycosis