title: Effect of multidisciplinary interventions on quality of life in obese children: a systematic review and meta-analysis.
abstract: OBJECTIVE
  To assess the effect of multidisciplinary intervention (MI) programs for overweight and obese children on quality of life (QoL).
  
  
  METHODS
  Medline, EMBASE, Web of Science and Cochrane databases were searched for relevant studies without date restrictions up to July 2014. Included were randomized controlled trials and controlled clinical trials evaluating an MI aimed to reduce weight in overweight children and reporting QoL. The risk of bias of the included studies was assessed using the Cochrane guidelines. Data were pooled for short- (up to 6 months) and long-term (12-18 months) effects using a random effects model.
  
  
  RESULTS
  In total, 11 studies were included, studying a total of 997 children aged 3-18 years. No significant differences were found between MI and control interventions on short-term QoL outcomes [mean difference (MD) 1.73, 95 % confidence interval (CI) -0.26 to 3.73 on a 0-100 scale]. Long-term results showed a nonsignificant trend toward a higher QoL in children following an MI program compared with control interventions (MD 4.40 95 % CI -0.12 to 8.92).
  
  
  CONCLUSIONS
  There is insufficient evidence that MI programs, aimed to reduce weight in overweight and obese children, improve QoL.
authors.affiliation: Department of General Practice, Erasmus MC, University Medical Center, Room Na-1923, PO Box 2040, 3000 CA, Rotterdam, The Netherlands, k.ligthart@erasmusmc.nl.
authors.forename: Kelly A M
authors.initials: KA
authors.lastname: Ligthart
authors.forename: Winifred D
authors.initials: WD
authors.lastname: Paulis
authors.forename: Dewi
authors.initials: D
authors.lastname: Djasmo
authors.forename: Bart W
authors.initials: BW
authors.lastname: Koes
authors.forename: Marienke
authors.initials: M
authors.lastname: van Middelkoop
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D033183:Interdisciplinary Communication; D008297:Male; D009765:Obesity / Q000150:complications*; D050177:Overweight / Q000150:complications*; D011788:Quality of Life; D012307:Risk Factors