title: Eating disorders in schizophrenia: implications for research and management.
abstract: Objective. Despite evidence from case series, the comorbidity of eating disorders (EDs) with schizophrenia is poorly understood. This review aimed to assess the epidemiological and clinical characteristics of EDs in schizophrenia patients and to examine whether the management of EDs can be improved. Methods. A qualitative review of the published literature was performed using the following terms: "schizophrenia" in association with "eating disorders," "anorexia nervosa," "bulimia nervosa," "binge eating disorder," or "night eating syndrome." Results. According to our literature review, there is a high prevalence of comorbidity between schizophrenia and EDs. EDs may occur together with or independent of psychotic symptoms in these patients. Binge eating disorders and night eating syndromes are frequently found in patients with schizophrenia, with a prevalence of approximately 10%. Anorexia nervosa seems to affect between 1 and 4% of schizophrenia patients. Psychopathological and neurobiological mechanisms, including effects of antipsychotic drugs, should be more extensively explored. Conclusions. The comorbidity of EDs in schizophrenia remains relatively unexplored. The clearest message of this review is the importance of screening for and assessment of comorbid EDs in schizophrenia patients. The management of EDs in schizophrenia requires a multidisciplinary approach to attain maximized health outcomes. For clinical practice, we propose some recommendations regarding patient-centered care.
authors.affiliation: Department of Endocrinology, University of Picardie-Jules Verne, CHU d'Amiens, Amiens, France ; Department of Nutrition, Hôpital maritime, Assistance Publique-Hôpitaux de Paris (AP-HP), 62600 Berck, France.
authors.forename: Youssef
authors.identifier: 0000-0002-4188-1428
authors.initials: Y
authors.lastname: Kouidrat
authors.affiliation: Psychiatry Department and SCA-lab, PSYchiC team, Université de Lille, 59100 Lille, France.
authors.forename: Ali
authors.identifier: 0000-0002-9029-2910
authors.initials: A
authors.lastname: Amad
authors.affiliation: Department of Endocrinology, University of Picardie-Jules Verne, CHU d'Amiens, Amiens, France.
authors.forename: Jean-Daniel
authors.identifier: 0000-0001-7167-9872
authors.initials: JD
authors.lastname: Lalau
authors.affiliation: Department of Psychiatry, Erasme Hospital, ULB, 1070 Brussels, Belgium.
authors.forename: Gwenole
authors.initials: G
authors.lastname: Loas