title: Cortical inhibition effect in musicians and non-musicians using P300 with and without contralateral stimulation.
abstract: BACKGROUND
  Musicians have more robust and efficient neural responses in the cortical and sub-cortical regions, demonstrating that musical experience benefits the processing of both non-linguistic and linguistic stimuli.
  
  
  OBJECTIVE
  This study aimed to verify P300's latency and amplitude behavioral using contralateral stimulation in musicians and non-musicians.
  
  
  METHODS
  This was a case-control study. Subjects were divided in two groups: musicians, comprising 30 professional musicians, and non-musicians, comprising 25 subjects without musical experience.
  
  
  RESULTS
  The present study showed that the musicians had lower latencies and higher amplitudes than the non-musicians in the P300 without contralateral noise. For the P300 amplitude values, the difference between groups persisted, and the musicians presented significantly higher amplitude values compared with the non-musicians; additionally, the analysis of the noise effect on the P300 response showed that the latency values were significantly increased in the musicians.
  
  
  CONCLUSIONS
  The central auditory nervous system of musicians presents peculiar characteristics of electrophysiological responses probably due to the plasticity imposed by musical practice.
authors.affiliation: Departament of Physiotherapy, Speech and Language Therapy, Faculdade de Medicina, Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil. Electronic address: cmrabelo@gmail.com.
authors.forename: Camila Maia
authors.initials: CM
authors.lastname: Rabelo
authors.affiliation: Departament of Physiotherapy, Speech and Language Therapy, Faculdade de Medicina, Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
authors.forename: Ivone Ferreira
authors.initials: IF
authors.lastname: Neves-Lobo
authors.affiliation: Departament of Physiotherapy, Speech and Language Therapy, Faculdade de Medicina, Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
authors.forename: Caroline Nunes
authors.initials: CN
authors.lastname: Rocha-Muniz
authors.affiliation: Departament of Physiotherapy, Speech and Language Therapy, Faculdade de Medicina, Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
authors.forename: Thalita
authors.initials: T
authors.lastname: Ubiali
authors.affiliation: Departament of Physiotherapy, Speech and Language Therapy, Faculdade de Medicina, Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
authors.forename: Eliane
authors.initials: E
authors.lastname: Schochat
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001307:Auditory Perception; D016022:Case-Control Studies; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009146:Music; D011930:Reaction Time; D055815:Young Adult
keywords: Audição; Electrophysiology; Eletrofisiologia; Event-related potentials, P300; Hearing; Music; Música; Potencial evocado P300