title: Circumvallate placenta: associated clinical manifestations and complications-a retrospective study.
abstract: Aims. To analyze the pregnancy outcomes of circumvallate placenta retrospectively and to predict circumvallate placenta during pregnancy based on its clinical features. Methods. The pregnancy outcomes of 92 women with circumvallate placenta who delivered live singletons at a tertiary care center between January 2000 and September 2012 were compared with those of 9057 controls. Results. Women with circumvallate placenta were associated with higher incidences of preterm delivery (64.1%), placental abruption (10.9%), emergency cesarean section (45.6%), small-for-gestational age (36.9%), neonatal death (8.9%), neonatal intensive care unit admission (55.4%), and chronic lung disease (33.9%). When vaginal bleeding during the second trimester and premature chemical rupture of membranes (PCROM) were both used as predictive factors for circumvallate placenta, the sensitivity was 28.8% and specificity was 99.9%. Conclusion. With circumvallate placenta, pregnancy outcomes were poor and had characteristic clinical manifestations. In women with both vaginal bleeding and PCROM during pregnancy, circumvallate placenta should be strongly suspected.
authors.affiliation: Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, 4-57 Urafunecyou, Minami-ku, Yokohama, Kanagawa 232-0024, Japan.
authors.forename: Hanako
authors.identifier: 0000-0002-0994-2323
authors.initials: H
authors.lastname: Taniguchi
authors.affiliation: Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, 4-57 Urafunecyou, Minami-ku, Yokohama, Kanagawa 232-0024, Japan.
authors.forename: Shigeru
authors.identifier: 0000-0001-5307-575X
authors.initials: S
authors.lastname: Aoki
authors.affiliation: Department of Biostatistics and Epidemiology, Yokohama City University Graduate School of Medicine and University Medical Center, Yokohama, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Sakamaki
authors.affiliation: Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, 4-57 Urafunecyou, Minami-ku, Yokohama, Kanagawa 232-0024, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Kurasawa
authors.affiliation: Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, 4-57 Urafunecyou, Minami-ku, Yokohama, Kanagawa 232-0024, Japan.
authors.forename: Mika
authors.initials: M
authors.lastname: Okuda
authors.affiliation: Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center, 4-57 Urafunecyou, Minami-ku, Yokohama, Kanagawa 232-0024, Japan.
authors.forename: Tsuneo
authors.initials: T
authors.lastname: Takahashi
authors.affiliation: Department of Obstetrics and Gynecology, Yokohama City University Hospital, Yokohama, Japan.
authors.forename: Fumiki
authors.initials: F
authors.lastname: Hirahara