title: The burden of disease in Spain: results from the global burden of disease study 2010.
abstract: BACKGROUND
  We herein evaluate the Spanish population's trends in health burden by comparing results of two Global Burden of Diseases, Injuries, and Risk Factors Studies (the GBD studies) performed 20 years apart.
  
  
  METHODS
  Data is part of the GBD study for 1990 and 2010. We present results for mortality, years of life lost (YLLs), years lived with disability, and disability-adjusted life years (DALYs) for the Spanish population. Uncertainty intervals for all measures have been estimated.
  
  
  RESULTS
  Non-communicable diseases accounted for 3,703,400 (95% CI 3,648,270-3,766,720) (91.3%) of 4,057,400 total deaths, in the Spanish population. Cardiovascular and circulatory diseases were the main cause of mortality among non-communicable diseases (34.7% of total deaths), followed by neoplasms (27.1% of total deaths). Neoplasms, cardiovascular and circulatory diseases, and chronic respiratory diseases were the top three leading causes for YLLs. The most important causes of DALYs in 2010 were neoplasms, cardiovascular and circulatory diseases, musculoskeletal disorders, and mental and behavioral disorders.
  
  
  CONCLUSIONS
  Mortality and disability in Spain have become even more linked to non-communicable diseases over the last years, following the worldwide trends. Cardiovascular and circulatory diseases, neoplasms, mental and behavioral disorders, and neurological disorders are the leading causes of mortality and disability. Specific focus is needed from health care providers and policy makers to develop health promotion and health education programs directed towards non-communicable disorders.
authors.affiliation: Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu. Dr Antoni Pujades, 42, 08830 Sant Boi de Llobregat, Barcelona, Spain. jmharo@pssjd.org.|Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, Dr. Esquerdo 46, 28007, Madrid, Spain. jmharo@pssjd.org.
authors.forename: Josep Maria
authors.initials: JM
authors.lastname: Haro
authors.affiliation: Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu. Dr Antoni Pujades, 42, 08830 Sant Boi de Llobregat, Barcelona, Spain. s.tyrovolas@pssjd.org.|Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, Dr. Esquerdo 46, 28007, Madrid, Spain. s.tyrovolas@pssjd.org.
authors.forename: Stefanos
authors.initials: S
authors.lastname: Tyrovolas
authors.affiliation: Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu. Dr Antoni Pujades, 42, 08830 Sant Boi de Llobregat, Barcelona, Spain. noe.garin@pssjd.org.|Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, Dr. Esquerdo 46, 28007, Madrid, Spain. noe.garin@pssjd.org.
authors.forename: Noe
authors.initials: N
authors.lastname: Garin
authors.affiliation: Unitat de Reumatologia. Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Carrer de Sant Quintí, 89, 08026, Barcelona, Spain. cesardiaztorne@gmail.com.
authors.forename: Cesar
authors.initials: C
authors.lastname: Diaz-Torne
authors.affiliation: Instituto de Salud Musculoesquelética (InMusc), Calle Hilarión, Eslava 2, 28015, , Madrid, Spain. loreto.carmona@inmusc.eu.
authors.forename: Loreto
authors.initials: L
authors.lastname: Carmona
authors.affiliation: Institute of Bone and Joint Research, Royal North Shore Hospital, University of Sydney, Pacific Hwy, St Leonards, New South Wales, 2065, Australia. 37416lsr@comb.cat.|Institut d'Investigació Biomèdica de Bellvitge, Hospital Universitari de Bellvitge, Freixa Llarga s/n, 08907 L'Hospitalet de Llobregat, Barcelona, Spain. 37416lsr@comb.cat.
authors.forename: Lidia
authors.initials: L
authors.lastname: Sanchez-Riera
authors.affiliation: Rheumatology Division, Cruces University Hospital, Crystal-induced arthritis investigation team, BioCruces Health Investigation Institute, Plaza de Cruces 12, 48903, Baracaldo, Vizcaya, Spain. fperezruiz@telefonica.net.
authors.forename: Fernando
authors.initials: F
authors.lastname: Perez-Ruiz
authors.affiliation: Institute for Health Metrics and Evaluation, University of Washington, 2301 Fifth Avenue,mSuite 600, Seattle, WA, 98121, USA. cjlm@uw.ed.
authors.forename: Christopher J L
authors.initials: CJ
authors.lastname: Murray
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D017281:Cost of Illness; D006233:Persons with Disabilities / Q000706:statistics & numerical data*; D005260:Female; D014943:Global Health; D006305:Health Status Indicators; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D019057:Quality-Adjusted Life Years; D012307:Risk Factors; D013030:Spain