title: Application of non-thermal plasma reactor and Fenton reaction for degradation of ibuprofen.
abstract: Pharmaceutical compounds have been detected frequently in surface and ground water. Advanced Oxidation Processes (AOPs) were reported as very efficient for removal of various organic compounds. Nevertheless, due to incomplete degradation, toxic intermediates can induce more severe effects than the parent compound. Therefore, toxicity studies are necessary for the evaluation of possible uses of AOPs. In this study the effectiveness and capacity for environmental application of three different AOPs were estimated. They were applied and evaluated for removal of ibuprofen from water solutions. Therefore, two treatments were performed in a non-thermal plasma reactor with dielectric barrier discharge with and without a homogenous catalyst (Fe(2+)). The third treatment was the Fenton reaction. The degradation rate of ibuprofen was measured by HPLC-DAD and the main degradation products were identified using LC-MS TOF. Twelve degradation products were identified, and there were differences according to the various treatments applied. Toxicity effects were determined with two bioassays: Vibrio fischeri and Artemia salina. The efficiency of AOPs was demonstrated for all treatments, where after 15 min degradation percentage was over 80% accompanied by opening of the aromatic ring. In the treatment with homogenous catalyst degradation reached 99%. V. fischeri toxicity test has shown greater sensitivity to ibuprofen solution after the Fenton treatment in comparison to A. salina.
authors.affiliation: Center of Chemistry, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia.
authors.forename: Marijana
authors.initials: M
authors.lastname: Marković
authors.affiliation: Innovation Center, Faculty of Chemistry, University of Belgrade, P.O. Box 51, 11058 Belgrade 118, Serbia.
authors.forename: Milica
authors.initials: M
authors.lastname: Jović
authors.affiliation: Innovation Center, Faculty of Chemistry, University of Belgrade, P.O. Box 51, 11058 Belgrade 118, Serbia.
authors.forename: Dalibor
authors.initials: D
authors.lastname: Stanković
authors.affiliation: Faculty of Physics, University of Belgrade, P.O. Box 44, 11000 Belgrade, Serbia.
authors.forename: Vesna
authors.initials: V
authors.lastname: Kovačević
authors.affiliation: Faculty of Chemistry, University of Belgrade, P.O. Box 51, 11058 Belgrade 118, Serbia.
authors.forename: Goran
authors.initials: G
authors.lastname: Roglić
authors.affiliation: Center of Chemistry, Institute of Chemistry, Technology and Metallurgy, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia.
authors.forename: Gordana
authors.initials: G
authors.lastname: Gojgić-Cvijović
authors.affiliation: Faculty of Chemistry, University of Belgrade, P.O. Box 51, 11058 Belgrade 118, Serbia. Electronic address: manojlo@chem.bg.ac.rs.
authors.forename: Dragan
authors.initials: D
authors.lastname: Manojlović
mesh_terms: D006861:Hydrogen Peroxide / Q000737:chemistry*; D007052:Ibuprofen / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D008956:Models, Chemical; D058626:Plasma Gases
chemical_list: D058626:Plasma Gases; D006861:Hydrogen Peroxide; D007501:Iron; D007052:Ibuprofen
keywords: A. salina; AOPs; Ibuprofen removal; Non-thermal plasma; Toxicity; V. fischeri