title: Temporal trends in inflammatory bowel disease publications over a 19-years period.
abstract: OBJECTIVE
  To determine whether temporal changes occurred in the pediatric vs adult inflammatory bowel disease (IBD), both in terms of number and type of yearly published articles.
  
  
  METHODS
  We aimed to evaluate all PubMed-registered articles related to the field of IBD from January 1, 1993 and until December 31, 2011. We searched for articles using the key words "inflammatory bowel disease" or "Crohn's disease" or "ulcerative colitis" or "undetermined colitis", using the age filters of "child" or "adult". We repeated the search according to the total number per year of articles per type of article, for each year of the specified period. We studied randomized controlled trials, clinical trials, case reports, meta-analyses, letters to the editor, reviews, systematic reviews, practice guidelines, and editorials.
  
  
  RESULTS
  We identified 44645 articles over the 19 year-period. There were 8687 pediatric-tagged articles vs 19750 adult-tagged articles. Thus 16208 articles were unaccounted and not assigned a "pediatric" or "adult" tag by PubMed. There was an approximately 3-fold significant increase in all articles recorded both in pediatric and adult articles. This significant increase was true for nearly every category of article but the number of clinical trials, meta-analysis, and randomized controlled trials increased proportionally more than the number of "lower quality" articles such as editorials or letters to the editor. Very few guidelines were published every year.
  
  
  CONCLUSIONS
  There is a yearly linear increase in publications related to IBD. Relatively, there are more and more clinical trials and higher quality articles.
authors.affiliation: Yael Weintraub, Shlomi Cohen, Pediatric Gastroenterology and Nutrition Unit, "Dana-Dwek" Children's Hospital, Tel Aviv Medical Center, Tel Aviv 64239, Israel.
authors.forename: Yael
authors.initials: Y
authors.lastname: Weintraub
authors.affiliation: Yael Weintraub, Shlomi Cohen, Pediatric Gastroenterology and Nutrition Unit, "Dana-Dwek" Children's Hospital, Tel Aviv Medical Center, Tel Aviv 64239, Israel.
authors.forename: Francis B
authors.initials: FB
authors.lastname: Mimouni
authors.affiliation: Yael Weintraub, Shlomi Cohen, Pediatric Gastroenterology and Nutrition Unit, "Dana-Dwek" Children's Hospital, Tel Aviv Medical Center, Tel Aviv 64239, Israel.
authors.forename: Shlomi
authors.initials: S
authors.lastname: Cohen
mesh_terms: D000818:Animals; D015706:Bibliometrics; D035843:Biomedical Research / Q000639:trends*; D019317:Evidence-Based Medicine / Q000639:trends*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D010506:Periodicals as Topic / Q000639:trends*; D013997:Time Factors
keywords: Crohn’s disease; Inflammatory bowel disease; Meta-analysis; Randomized clinical trial; Ulcerative colitis