title: A randomized clinical trial compared the effect of intra-alveolar 0.2 % Chlorohexidine bio-adhesive gel versus 0.12% Chlorohexidine rinse in reducing alveolar osteitis following molar teeth extractions.
abstract: OBJECTIVE
  To evaluate socket healing, incidence of acute alveolar ostieitis (AO) and associated pain following single molar tooth extraction in patients who receive intra-alveolar 0.2% chlorhexidine (CHX) gel, and those who rinsed with 0.12 % CHX rinse.
  
  
  METHODS
  A prospective randomized clinical trial was conducted on two parallel groups of patients. Group 1 (141 patients): Rinsed with 0.12 % CHX rinse from the second postoperative day, two times daily for a week. Group2 (160 patients): Who had direct intra-alveolar application of 0.2% CHX gel and day 3 post-operatively. The socket was evaluated 3 and 7 day postoperatively for the presence of AO by checking probing tenderness in the socket, empty socket, food debris, halitosis and pain assessment by VAS.
  
  
  RESULTS
  Forty-eight AO cases were diagnosed out of 301 extractions (15.9%). In Group 1, 25 cases were found (17.7%) while 23 cases were found in Group 2 (14.4%). The difference was not statistically significant (p=0.428). Presence of empty socket and food debris in Group 1 were higher than in Group 2 but the difference was not statistically significant (p= 0.390 & p = 0.415). Occurrence of halitosis in Group 2 was more than Group 1, but the difference was not significant (p= 0.440). Statistical significance was found between AO in extraction done by root separation (29%) and those routinely extracted (12.3 %) (p=0.001).
  
  
  CONCLUSIONS
  Postoperative evaluation of molar extraction sockets that received direct intra-alveolar application of 0.2% CHX gel showed insignificant less occurrence of AO when compared with 0.12 % CHX rinse.
authors.affiliation: PO.BOX: 84891, Riyadh 11681, Saudi Arabia, nabumostafa@gmail.com.
authors.forename: Nedal-Abdullah
authors.initials: NA
authors.lastname: Abu-Mostafa
authors.forename: Abdullah
authors.initials: A
authors.lastname: Alqahtani
authors.forename: Mohammed
authors.initials: M
authors.lastname: Abu-Hasna
authors.forename: Ahmed
authors.initials: A
authors.lastname: Alhokail
authors.forename: Ammar
authors.initials: A
authors.lastname: Aladsani
mesh_terms: D000269:Adhesives / Q000008:administration & dosage*; D002710:Chlorhexidine / Q000008:administration & dosage*; D004368:Dry Socket / Q000209:etiology* / Q000517:prevention & control*; D005260:Female; D005782:Gels; D006801:Humans; D008297:Male; D008963:Molar / Q000601:surgery*; D009067:Mouthwashes / Q000008:administration & dosage*; D011446:Prospective Studies; D014081:Tooth Extraction / Q000009:adverse effects*; D020390:Tooth Socket
chemical_list: D000269:Adhesives; D005782:Gels; D009067:Mouthwashes; D002710:Chlorhexidine