title: Pediatric primary splenic angiosarcoma: an aggressive multidisciplinary approach to the oncologic management of a rare malignancy.
abstract: Primary splenic angiosarcoma is an extremely rare and aggressive neoplasm of the vasculature. Uniformly, primary splenic angiosarcoma is a fatal disease despite early diagnosis and treatment. Only patients with localized disease amenable to surgical resection achieve long-term, disease-free survival. We present a review of the literature and report a case of a 3-year-old girl with metastatic primary splenic angiosarcoma who was offered aggressive surgical and medical treatment with curative intent despite her advanced presentation.
authors.affiliation: Division of Pediatric Surgery, Department of Surgery, Children's Hospital at Montefiore Medical Center, 3415 Bainbridge Avenue, New York, NY 10467, USA. oserrano@montefiore.org.
authors.forename: Oscar K
authors.initials: OK
authors.lastname: Serrano
authors.forename: Esther
authors.initials: E
authors.lastname: Knapp
authors.forename: Kevin
authors.initials: K
authors.lastname: Huang
authors.forename: Galina
authors.initials: G
authors.lastname: Baran
authors.forename: Mindy
authors.initials: M
authors.lastname: Statter
authors.forename: Danielle
authors.initials: D
authors.lastname: McClain
authors.forename: Jonathan
authors.initials: J
authors.lastname: Gill
mesh_terms: D002648:Child; D003131:Combined Modality Therapy; D019468:Disease Management; D005260:Female; D006394:Hemangiosarcoma / Q000473:pathology / Q000628:therapy*; D006801:Humans; D016031:Liver Transplantation; D011379:Prognosis; D013160:Splenic Neoplasms / Q000473:pathology / Q000628:therapy*