title: Very late effects of postoperative atrial fibrillation on outcome of coronary artery bypass graft surgery.
abstract: BACKGROUND
  Atrial fibrillation (AF) after coronary artery bypass graft (CABG) is a common complication with potentially higher risk of adverse outcome and prolonged hospital stay.
  
  
  OBJECTIVE
  To determine the impact of postoperative AF (POAF) on long-term outcome in a large cohort of patients who underwent CABG.
  
  
  METHODS
  We conducted an observational cohort study of 989 patients who underwent isolated CABG with more than 5-year follow-up. Patient divided in two groups: patients with and without POAF.
  
  
  RESULTS
  In this study, atrial fibrillation developed after CABG in 156 patients (15.8%). Patients with POAF were generally older (P = 0.001) and presented more often with comorbidities including congestive heart failure (P = 0.001), hypertension (P = 0.001), peripheral vascular disease (P = 0.001), hyperlipidemia (P = 0.009), and renal failure (P = 0.001). Five-year mortality was observed in 23 (2.3%) patients. Patients with POAF had higher five-year mortality rate than those without POAF. Multivariate logistic analysis showed that AF after surgery has a strong effect on mortality (HR, 3.3; 95% CI, 0.04-10.8, P = 0.04) and morbidity rates (HR, 4.0; 95% CI, 2.35-6.96, P = 0.001).
  
  
  CONCLUSIONS
  Postoperative atrial fibrillation strongly predicts higher long-term mortality and morbidity following coronary artery bypass graft.
authors.affiliation: Cardiac Electrophysiology Research Center, Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Majid
authors.initials: M
authors.lastname: Haghjoo
authors.affiliation: Cardiac Electrophysiology Research Center, Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Mona
authors.initials: M
authors.lastname: Heidarali
authors.affiliation: Cardiac Electrophysiology Research Center, Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Salman
authors.initials: S
authors.lastname: Nikfarjam
authors.affiliation: Cardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Mohammadmahdi
authors.initials: M
authors.lastname: Peighambari
authors.affiliation: Heart Valve Disease Research Center, Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Alizadeh-Ghavidel
authors.affiliation: Heart Valve Disease Research Center, Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Saeid
authors.initials: S
authors.lastname: Hosseini
authors.affiliation: Department of Cardiac Anesthesiology, Rajaie Cardiovascular Medical and Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Jalali
keywords: Atrial Fibrillation; Coronary Disease; Morbidity; Mortality