title: First report on long-term clinical results after treatment of coronary bifurcation lesions with the Tryton dedicated bifurcation stent.
abstract: BACKGROUND
  To improve clinical outcomes after percutaneous coronary interventions of coronary bifurcation lesions, the Tryton Side Branch Stent™ (Tryton Medical, Durham) was developed. Registry studies evaluating the Tryton stent has shown promisingclinical results and the stent is currently compared with the provisional single stent strategy in a randomized trial. However, clinical results beyond one year are lacking, and therefore, we investigated the one- and two-year outcomes after Tryton stent placement in a single-center registry study.
  
  
  RESULTS
  All patients in our center in whom Tryton placement was attempted between October 2010 and December 2011 were included. Clinical outcomes were defined as cardiac death, any myocardial infarction (MI), target vessel revascularization (TVR), target lesion revascularization (TLR), stent thrombosis (ST), and target vessel failure (TVF; composite of cardiac death, MI, and TVR). Event rates were estimated using the Kaplan-Meier method. We included 91 patients. Almost half (42%) of the patients included had acute coronary syndrome (ACS) as indication for PCI (12% unstable angina, 14% NSTEMI, and 16% STEMI). Median follow-up duration was 713 days (IQR 617-840). TVF rates were 14.5% (one year) and 20.3% (two year). Two-year cardiac death, MI, TVR, TLR and ST rates were 4.4%, 10.2%, 12.7%, 9.2%, and 2.2%, respectively.
  
  
  CONCLUSIONS
  In this single-center registry, use of the Tryton stent was associated with acceptable clinical outcomes at two-year follow-up.
authors.forename: Maik J
authors.initials: MJ
authors.lastname: Grundeken
authors.forename: Robin P
authors.initials: RP
authors.lastname: Kraak
authors.forename: Jan
authors.initials: J
authors.lastname: Baan
authors.forename: E Karin
authors.initials: EK
authors.lastname: Arkenbout
authors.forename: Jan J
authors.initials: JJ
authors.lastname: Piek
authors.forename: M Marije
authors.initials: MM
authors.lastname: Vis
authors.forename: Jose P S
authors.initials: JP
authors.lastname: Henriques
authors.forename: Karel T
authors.initials: KT
authors.lastname: Koch
authors.forename: Jan G P
authors.initials: JG
authors.lastname: Tijssen
authors.forename: Robbert J
authors.initials: RJ
authors.lastname: de Winter
authors.forename: Joanna J
authors.initials: JJ
authors.lastname: Wykrzykowska
mesh_terms: D000046:Academic Medical Centers; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods* / Q000401:mortality; D015331:Cohort Studies; D017023:Coronary Angiography / Q000379:methods; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008670:Metals; D008875:Middle Aged; D009426:Netherlands; D011446:Prospective Studies; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012042:Registries; D018570:Risk Assessment; D012720:Severity of Illness Index; D015607:Stents; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D008670:Metals