title: Genetic factors adaptive in a malarial environment may increase the risk of type 1 diabetes.
authors.affiliation: Department of Biomedicine and Prevention, University of Rome Tor Vergata, School of Medicine, Rome, Italy.
authors.forename: Fulvia
authors.initials: F
authors.lastname: Gloria-Bottini
authors.forename: Egidio
authors.initials: E
authors.lastname: Bottini
mesh_terms: D000222:Adaptation, Physiological / Q000235:genetics*; D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics*; D016022:Case-Control Studies; D002648:Child; D004268:DNA-Binding Proteins; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology / Q000209:etiology*; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D007231:Infant, Newborn; D007558:Italy / Q000453:epidemiology; D008288:Malaria / Q000453:epidemiology / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*; D016159:Tumor Suppressor Protein p53 / Q000235:genetics*
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D004268:DNA-Binding Proteins; C097695:TADA2A protein, human; C495901:TP53 protein, human; D014157:Transcription Factors; D016159:Tumor Suppressor Protein p53
keywords: P53 codon 72; adenosine deaminase; malaria; type 1 diabetes