title: The prevalence of Group B Streptococus recto-vaginal colonization and antimicrobial susceptibility pattern in pregnant mothers at two hospitals of Addis Ababa, Ethiopia.
abstract: BACKGROUND
  Group B streptococcus (GBS) has been implicated in adverse pregnancy outcomes. GBS recto-vaginal colonization rates significantly vary among different communities and geographic locations. Limited data is available on the prevalence and effects of GBS recto-vaginal colonization among pregnant mothers in developing countries like Ethiopia.
  
  
  OBJECTIVE
  To assess the prevalence of GBS recto-vaginal colonization among near term pregnant mothers and the antimicrobial susceptibility pattern of the isolates.
  
  
  METHODS
  A cross sectional descriptive study was conducted on pregnant mothers at gestational age of 35-37 weeks attending Ante Natal Clinics at Ghandi Memorial (GMH) and Tikur Anbessa Specialized Hospital (TASH) in Addis Ababa. Samples from lower genital tract and rectum were collected and cultured for GBS on CHROM agar Strep B.
  
  
  RESULTS
  Twenty two of the 300 pregnant mothers (7.2%) studied were found to have positive GBS recto-vaginal culture. Twelve isolates (55%) were sensitive to penicillin while 20 (91%) were sensitive to ampicilline. All isolates except one were sensitive to Erythromycin.
  
  
  CONCLUSIONS
  The study showed recto-vaginal GBS colonization among near term pregnant mothers is reasonably high in our community calling for the need to screen mothers near term and provide appropriate antimicrobial prophylaxis to prevent potential adverse maternal and neonatal outcome.
authors.forename: Zufan Lakew
authors.initials: ZL
authors.lastname: Woldu
authors.forename: Tatek Gebreegziabher
authors.initials: TG
authors.lastname: Teklehaimanot
authors.affiliation: Department of Gynecology and Obstetrics, Addis Ababa University, School of Medicine, P,O, BOX: 27954/1000, AA, Addis Ababa, Ethiopia. siteet@yahoo.com.
authors.forename: Sisay Teklu
authors.initials: ST
authors.lastname: Waji
authors.forename: Mahlet Yigeremu
authors.initials: MY
authors.lastname: Gebremariam
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents; D003430:Cross-Sectional Studies; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D015995:Prevalence; D012007:Rectum / Q000382:microbiology; D013290:Streptococcal Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000302:isolation & purification*; D014621:Vagina / Q000382:microbiology; D014623:Vaginal Diseases / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents