title: Update in the myeloproliferative neoplasms.
abstract: The differential diagnosis of haematological abnormalities, such as leucocytosis, erythocytosis, thrombocytosis or indeed anaemia, is wide and disarming. Here we report on significant updates in the differential diagnosis of erythrocyosis and thrombocytosis presenting a simplified schema for the clinician. We then move to discuss significant advances in this field which have followed a series of key molecular findings, most specifically those affecting the JAK/STAT pathway.
authors.affiliation: Department of Haematology Guy's and St Thomas' Hospital, London, UK claire.harrison@gstt.nhs.uk.
authors.forename: Claire N
authors.initials: CN
authors.lastname: Harrison
authors.affiliation: CCRCB, Queen's University, Belfast, UK.
authors.forename: Mary F
authors.initials: MF
authors.lastname: McMullin
mesh_terms: D006801:Humans; D009196:Myeloproliferative Disorders; D011086:Polycythemia
keywords: Polycythaemia; erythrocytosis; myelofibrosis; myeloproliferative; thrombocytosis