title: Chemotherapy advances in locally advanced head and neck cancer.
abstract: The management of locally advanced unresectable head and neck squamous cell cancer (HNSCC) continues to improve. One of the major advances in the treatment of HNSCC was the addition of chemotherapy to radiation in the treatment of non-surgical patients. The majority of the data regarding chemotherapy in HNSCC involve cisplatin chemotherapy with concurrent radiation. However, several new approaches have included targeted therapy against epidermal growth factor receptor and several recent studies have explored the role of induction chemotherapy in the treatment of HNSCC. The purpose of this article is to provide an overview of the role of chemotherapy in the treatment of locally advanced HNSCC.
authors.affiliation: Peter Georges, Kumar Rajagopalan, Chady Leon, Priya Singh, Kamyar Nader, Department of Medical Oncology, Cooper University Hospital, Camden, NJ 08103, United States.
authors.forename: Peter
authors.initials: P
authors.lastname: Georges
authors.affiliation: Peter Georges, Kumar Rajagopalan, Chady Leon, Priya Singh, Kamyar Nader, Department of Medical Oncology, Cooper University Hospital, Camden, NJ 08103, United States.
authors.forename: Kumar
authors.initials: K
authors.lastname: Rajagopalan
authors.affiliation: Peter Georges, Kumar Rajagopalan, Chady Leon, Priya Singh, Kamyar Nader, Department of Medical Oncology, Cooper University Hospital, Camden, NJ 08103, United States.
authors.forename: Chady
authors.initials: C
authors.lastname: Leon
authors.affiliation: Peter Georges, Kumar Rajagopalan, Chady Leon, Priya Singh, Kamyar Nader, Department of Medical Oncology, Cooper University Hospital, Camden, NJ 08103, United States.
authors.forename: Priya
authors.initials: P
authors.lastname: Singh
authors.affiliation: Peter Georges, Kumar Rajagopalan, Chady Leon, Priya Singh, Kamyar Nader, Department of Medical Oncology, Cooper University Hospital, Camden, NJ 08103, United States.
authors.forename: Nadir
authors.initials: N
authors.lastname: Ahmad
authors.affiliation: Peter Georges, Kumar Rajagopalan, Chady Leon, Priya Singh, Kamyar Nader, Department of Medical Oncology, Cooper University Hospital, Camden, NJ 08103, United States.
authors.forename: Kamyar
authors.initials: K
authors.lastname: Nader
authors.affiliation: Peter Georges, Kumar Rajagopalan, Chady Leon, Priya Singh, Kamyar Nader, Department of Medical Oncology, Cooper University Hospital, Camden, NJ 08103, United States.
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Kubicek
keywords: Chemotherapy; Head and neck cancer; Induction