title: Past experience resets behavior: CaMK takes the heat.
abstract: How past experiences reshape behavior is not well understood. In this issue, two studies (Schild et al., 2014; Yu et al., 2014) dissected the molecular mechanisms underlying experience-dependent plasticity in thermosensory behavior. They show that Ca(2+)/calmodulin-dependent kinase I (CaMKI) regulates thermal preferences according to past experience.
authors.affiliation: Life Sciences Institute and Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
authors.forename: Swathi
authors.initials: S
authors.lastname: Yadlapalli
authors.affiliation: Life Sciences Institute and Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
authors.forename: Khursheed A
authors.initials: KA
authors.lastname: Wani
authors.affiliation: Life Sciences Institute and Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: shawnxu@umich.edu.
authors.forename: X Z Shawn
authors.initials: XZ
authors.lastname: Xu