title: A novel dispersive solid-phase extraction method using metal-organic framework MIL-101 as the adsorbent for the analysis of benzophenones in toner.
abstract: Metal-organic frameworks (MOFs) have been paid widespread attention in the field of adsorption and separation materials due to its porosity, large specific surface area, unsaturated metal-ligand sites and structural diversity. In this study, the green powder MIL-101 was synthesized and used for the extraction of benzophenone, 2,4-dihydroxybenzophenone and 2-hydroxy-4-methoxy-benzophenone from toner samples for the first time. The synthesized MIL-101 was characterized by X-ray diffraction, scanning electron microscopy, thermogravimetry and nitrogen adsorption porosimetry. The MIL-101 was applied as the dispersive solid phase extraction (DSPE) adsorbent for the extraction and preconcentration of benzophenone, 2,4-dihydroxybenzophenone and 2-hydroxy-4-methoxy-benzophenone from toner samples. The extraction conditions were investigated. Under the optimized conditions, a DSPE-HPLC method for the determination of benzophenone, 2,4-dihydroxybenzophenone and 2-hydroxy-4-methoxy-benzophenone was developed. The method yielded a linear calibration curve in the concentration ranges from 4.0 to 3500 μg L(-1) for the three analytes in toner samples with regression coefficients (r(2)) of 0.9992, 0.9999 and 0.9990, respectively. Limits of detection were 1.2, 1.2 and 0.9 μg L(-1), respectively. Both the intra-day and inter-day precisions (RSDs) were <10%.
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Li
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China.
authors.forename: Quanfei
authors.initials: Q
authors.lastname: Zhu
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China.
authors.forename: Jianlin
authors.initials: J
authors.lastname: Huang
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China.
authors.forename: Xueping
authors.initials: X
authors.lastname: Dang
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China. Electronic address: hxch@hubu.edu.cn.
authors.forename: Huaixia
authors.initials: H
authors.lastname: Chen
mesh_terms: D000327:Adsorption; D001577:Benzophenones / Q000302:isolation & purification*; D002138:Calibration; D002851:Chromatography, High Pressure Liquid; D056831:Coordination Complexes / Q000737:chemistry*; D003358:Cosmetics / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D000073396:Metal-Organic Frameworks; D052616:Solid Phase Extraction / Q000379:methods; D013473:Sunscreening Agents / Q000302:isolation & purification*
chemical_list: D001577:Benzophenones; D056831:Coordination Complexes; D003358:Cosmetics; C000589635:MIL-101; D000073396:Metal-Organic Frameworks; D013473:Sunscreening Agents; C047723:benzophenone; C005290:oxybenzone; C121479:2,4-dihydroxybenzophenone
keywords: 2,4-Dihydroxybenzophenone; 2-Hydroxy-4-methoxy-benzophenone; Benzophenone; Dispersive solid-phase extraction (DSPE); Metal-organic framework (MOFs); Toner samples