title: Surgical excision followed by low dose rate radiotherapy in the management of resistant keloids.
abstract: BACKGROUND
  Depending on the cause, 40-90% of every deep dermis insult ends up in scar formation. Several modalities have been suggested as a treatment but a high rate of recurrence is reported in most of those interventions. High dose radiotherapy has been shown to be effective in reducing the recurrence rate. This study tried to determine the effectiveness of low dose rate radiotherapy following surgical excision in treating resistant keloids.
  
  
  METHODS
  Between January 2008 and April 2011, seventeen patients (mostly burn patients) with 26 keloids went through surgical resection followed by radiotherapy. A total dose of 15 Gy in 5 fractions was administered to the areas of scar formation.
  
  
  RESULTS
  All patients were followed for at least 11 months (mostly for 20 months). No recurrence occurred. There was no complication or adverse effect.
  
  
  CONCLUSIONS
  Surgical excision followed by low dose postoperative radiotherapy was an efficient treatment for keloids that were resistant to many other modalities.
authors.affiliation: Shiraz Burn Research Center, Division of Plastic and Reconstructive Surgery, Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran;
authors.forename: Ali Akbar
authors.initials: AA
authors.lastname: Mohammadi
authors.affiliation: Department of Radiation Oncology, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Mohammadian Panah
authors.affiliation: Shiraz Burn Research Center, Division of Plastic and Reconstructive Surgery, Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran;
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Pakyari
authors.affiliation: Shiraz Burn Research Center, Division of Plastic and Reconstructive Surgery, Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran;
authors.forename: Raziyeh
authors.initials: R
authors.lastname: Tavakol
authors.affiliation: Shiraz Burn Research Center, Division of Plastic and Reconstructive Surgery, Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran;
authors.forename: Iman
authors.initials: I
authors.lastname: Ahrary
authors.affiliation: Shiraz Burn Research Center, Division of Plastic and Reconstructive Surgery, Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran;
authors.forename: Seyed Morteza
authors.initials: SM
authors.lastname: Seyed Jafari
authors.affiliation: Shiraz Burn Research Center, Division of Plastic and Reconstructive Surgery, Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran;
authors.forename: Maryam
authors.initials: M
authors.lastname: Sharifian
keywords: Keloid; Radiotherapy; Surgical excision