title: Bone health, vitamin D and lupus.
abstract: The prevalence of vitamin D deficiency and insufficiency among patients with systemic lupus erythematosus is high. This is likely due to photoprotection measures in addition to intrinsic factors of the disease. Low levels of vitamin D increase the risk of low bone mineral density and fracture. Vitamin D deficiency could also have undesirable effects on patients' immune response, enhancing mechanisms of loss of tolerance and autoimmunity. Vitamin D levels should be periodically monitored and patients should be treated with the objective of reaching vitamin D levels higher than 30-40 ng/ml.
authors.affiliation: Sección de Enfermedades Autoinmunes Sistémicas, Servicio de Reumatología, Hospital Universitario Puerta de Hierro Majadahonda. Majadahonda, Madrid, España.
authors.forename: Clara
authors.initials: C
authors.lastname: Sangüesa Gómez
authors.affiliation: Sección de Enfermedades Autoinmunes Sistémicas, Servicio de Reumatología, Hospital Universitario Puerta de Hierro Majadahonda. Majadahonda, Madrid, España.
authors.forename: Bryan Josué
authors.initials: BJ
authors.lastname: Flores Robles
authors.affiliation: Sección de Enfermedades Autoinmunes Sistémicas, Servicio de Reumatología, Hospital Universitario Puerta de Hierro Majadahonda. Majadahonda, Madrid, España. Electronic address: jlandreu@arrakis.es.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Andréu
mesh_terms: D002318:Cardiovascular Diseases / Q000209:etiology; D019587:Dietary Supplements; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology; D010024:Osteoporosis / Q000209:etiology*; D014807:Vitamin D / Q000627:therapeutic use; D014808:Vitamin D Deficiency / Q000188:drug therapy / Q000209:etiology*; D014815:Vitamins / Q000627:therapeutic use
chemical_list: D014815:Vitamins; D014807:Vitamin D
keywords: Lupus eritematoso sistémico; Osteoporosis; Systemic lupus erythematosus; Vitamin D; Vitamina D