title: Bronchiolitis obliterans organizing pneumonia in patients with autoimmune rheumatic diseases.
abstract: Bronchiolitis obliterans organizing pneumonia (BOOP) is defined by buds of granulation tissue within lung distal airspaces. The diagnosis requires the histopathologic evidence of organizing pneumonia along with a suggestive clinical and radiographic pattern. This disorder is characterized by a good response to corticosteroids and an excellent prognosis. It can occur in association with a broad spectrum of clinical conditions or can be isolated, in this last case named cryptogenic organizing pneumonia. We searched for BOOP in patients with autoimmune rheumatic diseases (ARD) in the literature, and we found 32 well-documented cases. We reported here demographic features, manifestations, treatment and outcome of patients with BOOP associated with ARD. Notably, BOOP can be the presenting feature in some patients with ARD; thus, a close follow-up of patients with BOOP is recommended.
authors.affiliation: Internal Medicine Department, Biomedical Institute of Malaga (IBIMA), University Hospitals, Regional and Clinical Virgen de la Victoria of Malaga, Málaga, Spain.
authors.forename: Carmen Maria Lara
authors.initials: CM
authors.lastname: Rojas
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Borella
authors.forename: Lavinia
authors.initials: L
authors.lastname: Palma
authors.forename: Silvio
authors.initials: S
authors.lastname: Ragozzino
authors.forename: Enrique
authors.initials: E
authors.lastname: De Ramón
authors.forename: Ricardo
authors.initials: R
authors.lastname: Gomez-Huelgas
authors.forename: Leonardo
authors.initials: L
authors.lastname: Punzi
authors.forename: Andrea
authors.initials: A
authors.lastname: Doria
mesh_terms: D001327:Autoimmune Diseases / Q000150:complications* / Q000175:diagnosis; D018549:Cryptogenic Organizing Pneumonia / Q000150:complications* / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D006801:Humans; D012216:Rheumatic Diseases / Q000150:complications* / Q000175:diagnosis