title: Malignant granular cell tumor of the foot-multimodality imaging findings and literature review.
abstract: We describe how the combination of imaging and histologic findings was essential in establishing a preoperative diagnosis of an extremely rare malignant granular cell tumor (GrCT) occurring in the lower extremity of a 17-year-old man. Magnetic resonance imaging demonstrated a large infiltrative tumor of heterogeneous intermediate signal intensity on both T1- and T2-weighted sequences. Subsequent computed tomography (CT) and fluorodeoxyglucose positron emission tomography CT scans of the patient revealed distant nodal and skeletal metastases.
authors.affiliation: Department of Radiology, Vancouver General Hospital, Vancouver, BC, Canada. Electronic address: tien_jin_tan@cgh.com.sg.
authors.forename: Tien Jin
authors.initials: TJ
authors.lastname: Tan
authors.affiliation: Department of Pathology, Vancouver General Hospital, Vancouver, BC, Canada.
authors.forename: Ali H
authors.initials: AH
authors.lastname: Alassiri
authors.affiliation: Department of Pathology, Vancouver General Hospital, Vancouver, BC, Canada.
authors.forename: Tony L
authors.initials: TL
authors.lastname: Ng
authors.affiliation: Department of Radiology, Vancouver General Hospital, Vancouver, BC, Canada.
authors.forename: Paul I
authors.initials: PI
authors.lastname: Mallinson
authors.affiliation: Department of Radiology, Vancouver General Hospital, Vancouver, BC, Canada.
authors.forename: Peter L
authors.initials: PL
authors.lastname: Munk
mesh_terms: D000293:Adolescent; D062005:Biopsy, Large-Core Needle; D019788:Fluorodeoxyglucose F18; D005534:Foot Diseases / Q000175:diagnosis* / Q000628:therapy; D016586:Granular Cell Tumor / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Computed tomography; Magnetic resonance imaging; Malignant granular cell tumor; Positron emission tomography; Soft tissue neoplasm