title: Single-shot speckle noise reduction by interleaved optical coherence tomography.
abstract: Speckle noise is one of the dominant factors that degrade image quality in optical coherence tomography (OCT). Here, we propose a new strategy, interleaved OCT (iOCT), for spatial compounding and angular compounding. We demonstrate the efficiency of compounding with iOCT to restrain speckle noise without compromising imaging speed in phantoms and tissue samples.
authors.forename: Lian
authors.initials: L
authors.lastname: Duan
authors.forename: Hee Yoon
authors.initials: HY
authors.lastname: Lee
authors.forename: Gary
authors.initials: G
authors.lastname: Lee
authors.forename: Monica
authors.initials: M
authors.lastname: Agrawal
authors.forename: Gennifer T
authors.initials: GT
authors.lastname: Smith
authors.forename: Audrey K
authors.initials: AK
authors.lastname: Ellerbee
mesh_terms: D000818:Animals; D004867:Equipment Design; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D019047:Phantoms, Imaging; D013552:Swine; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*; D001743:Urinary Bladder / Q000033:anatomy & histology