title: Minimal residual disease monitored after induction therapy by RQ-PCR can contribute to tailor treatment of patients with t(8;21) RUNX1-RUNX1T1 rearrangement.
authors.affiliation: Clinica Oncoematologia Pediatrica, Università di Padova, Padova martina.pigazzi@unipd.it.
authors.forename: Martina
authors.initials: M
authors.lastname: Pigazzi
authors.affiliation: Clinica Oncoematologia Pediatrica, Università di Padova, Padova.
authors.forename: Elena
authors.initials: E
authors.lastname: Manara
authors.affiliation: Clinica Oncoematologia Pediatrica, Università di Padova, Padova.
authors.forename: Barbara
authors.initials: B
authors.lastname: Buldini
authors.affiliation: Clinica Oncoematologia Pediatrica, Università di Padova, Padova.
authors.forename: Valzerda
authors.initials: V
authors.lastname: Beqiri
authors.affiliation: Clinica Oncoematologia Pediatrica, Università di Padova, Padova.
authors.forename: Valeria
authors.initials: V
authors.lastname: Bisio
authors.affiliation: Clinica Oncoematologia Pediatrica, Università di Padova, Padova.
authors.forename: Claudia
authors.initials: C
authors.lastname: Tregnago
authors.affiliation: Clinica Pediatrica, Università di Bologna, Ospedale "S. Orsola," Bologna.
authors.forename: Roberto
authors.initials: R
authors.lastname: Rondelli
authors.affiliation: Clinica Pediatrica, Università di Bologna, Ospedale "S. Orsola," Bologna.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Masetti
authors.affiliation: Clinica Oncoematologia Pediatrica, Università di Padova, Padova.
authors.forename: Maria Caterina
authors.initials: MC
authors.lastname: Putti
authors.affiliation: Oncoematologia Pediatrica, Ospedale Infantile "Regina Margherita", Torino.
authors.forename: Franca
authors.initials: F
authors.lastname: Fagioli
authors.affiliation: Clinica Pediatrica, Università di Milano-Bicocca, Fondazione MBBM, Ospedale S. Gerardo, Monza.
authors.forename: Carmelo
authors.initials: C
authors.lastname: Rizzari
authors.affiliation: Clinica Pediatrica, Università di Bologna, Ospedale "S. Orsola," Bologna.
authors.forename: Andrea
authors.initials: A
authors.lastname: Pession
authors.affiliation: Oncoematologia Pediatrica, IRCCS Ospedale Pediatrico Bambino Gesù, Roma, University of Pavia, Italy.
authors.forename: Franco
authors.initials: F
authors.lastname: Locatelli
authors.affiliation: Clinica Oncoematologia Pediatrica, Università di Padova, Padova.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Basso
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D002891:Chromosomes, Human, Pair 21; D002898:Chromosomes, Human, Pair 8; D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics*; D003561:Cytarabine / Q000627:therapeutic use; D016903:Drug Monitoring; D005047:Etoposide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015255:Idarubicin / Q000627:therapeutic use; D060828:Induction Chemotherapy / Q000379:methods; D007223:Infant; D007231:Infant, Newborn; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics / Q000401:mortality; D008297:Male; D009154:Mutation; D018365:Neoplasm, Residual; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D000075142:RUNX1 Translocation Partner 1 Protein; D016019:Survival Analysis; D014157:Transcription Factors / Q000235:genetics*; D014178:Translocation, Genetic
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D050676:Core Binding Factor Alpha 2 Subunit; D011518:Proto-Oncogene Proteins; D000075142:RUNX1 Translocation Partner 1 Protein; C493728:RUNX1 protein, human; C082222:RUNX1T1 protein, human; D014157:Transcription Factors; D003561:Cytarabine; D005047:Etoposide; D015255:Idarubicin
keywords: AIEOP; AML; AML1-ETO; CBFB-MYH11; RQ-PCR; RUNX1-RUNX1T1; inv(16); molecular MRD; pediatric; t(8;21)