title: Aggressive posterior retinopathy of prematurity in two of the triplets: a case report.
abstract: Aggressive posterior retinopathy of prematurity is identified as a rare, rapidly progressing and severe form of retinopathy of prematurity (ROP). Here, we report the diagnosis and treatment of aggressive posterior retinopathy of prematurity (APROP) in two of the triplets born at low birth weight and small gestational age. A case concerning two triplets who were born at 31 weeks' gestational age with low birth weight and reached bilateral threshold APROP was reported. The ROP of triplets A and B had the characteristic features of aggressive diseases, which were posterior location, prominence of plus disease and rapid progression. Low birth weight and small gestational age, multiple pregnancies, pregnancy-induced hypertension and older age of the mother might account for the presentations of APROP. These cases demonstrate the importance of early screening and diagnosis in APROP infants. Prompt and adequate laser photocoagulation with a large number of high-intensity closely performed spots and early retreatment could be effective and safe for preventing the progression of APROP with plus disease in zone 1 or 2 in premature triplets.
authors.affiliation: M.M., Department of Ophthalmology, First Hospital of Jilin University, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Wang
authors.affiliation: M.D., Department of Neurosurgery, First Hospital of Jilin University, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.affiliation: M.M., Department of Ophthalmology, First Hospital of Jilin University, China dongyu2014@yeah.net wangdan_366@hotmail.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Dong
authors.affiliation: M.D., Department of Ophthalmology, First Hospital of Jilin University, China; Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, China 22999443@qq.com.
authors.forename: E
authors.initials: E
authors.lastname: Song
mesh_terms: D000328:Adult; D018450:Disease Progression; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D017075:Laser Coagulation; D008028:Light Coagulation; D008297:Male; D012178:Retinopathy of Prematurity / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D014310:Triplets
keywords: Retinopathy; prematurity; triplet