title: Endoscopic endonasal optic nerve decompression in a patient with pseudotumor cerebri.
abstract: Pseudotumor cerebri (idiopathic intracranial hypertension) is a syndrome characterized by intracranial pressure elevation and associated signs and symptoms in the absence of a space-occupying intracranial lesion. The most common symptoms are visual loss and headache. Sometimes, surgical therapy is needed in patients who have no apparent response to medical therapy and exhibit a progressive course. Optic nerve decompression is an effective and recommended treatment approach for patients with pseudotumor cerebri in whom visual loss predominates. With the growing experience with endoscopic skull base approaches, this method has begun to be used as an alternative and effective treatment modality. In this study, we aimed to present the outcome of endoscopic endonasal optic nerve decompression and to review the literature on this treatment modality in 2 patients diagnosed with pseudotumor cerebri that was unresponsive to medical therapy and associated with progressive visual loss.
authors.affiliation: From the *Department of Neurosurgery, Ankara Numune Research and Education Hospital; and †Department of Neurosurgery, Ankara Ataturk Research and Education Hospital, Ankara, Turkey.
authors.forename: Ali Erdem
authors.initials: AE
authors.lastname: Yildirim
authors.forename: Derya
authors.initials: D
authors.lastname: Karaoglu
authors.forename: Denizhan
authors.initials: D
authors.lastname: Divanlioglu
authors.forename: Ahmed Eren
authors.initials: AE
authors.lastname: Secen
authors.forename: Ahmet Gurhan
authors.initials: AG
authors.lastname: Gurcay
authors.forename: Emin
authors.initials: E
authors.lastname: Cagil
authors.forename: Ahmed Deniz
authors.initials: AD
authors.lastname: Belen
mesh_terms: D000328:Adult; D019299:Decompression, Surgical; D005260:Female; D006801:Humans; D057605:Natural Orifice Endoscopic Surgery; D019635:Neurosurgical Procedures; D009666:Nose / Q000601:surgery; D009900:Optic Nerve / Q000601:surgery*; D011559:Pseudotumor Cerebri / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014786:Vision Disorders / Q000209:etiology / Q000601:surgery*