title: 2014 White Paper on recent issues in bioanalysis: a full immersion in bioanalysis (Part 1--small molecules by LCMS).
abstract: The 2014 8th Workshop on Recent Issues in Bioanalysis (8th WRIB), a 5-day full immersion in the evolving field of bioanalysis, took place in Universal City, California, USA. Close to 500 professionals from pharmaceutical and biopharmaceutical companies, contract research organizations and regulatory agencies worldwide convened to share, review, discuss and agree on approaches to address current issues of interest in bioanalysis. The topics covered included both small and large molecules, and involved LCMS, hybrid LBA/LCMS, LBA approaches and immunogenicity. From the prolific discussions held during the workshop, specific recommendations are presented in this 2014 White Paper. As with the previous years' editions, this paper acts as a practical tool to help the bioanalytical community continue advances in scientific excellence, improved quality and better regulatory compliance. Due to its length, the 2014 edition of this comprehensive White Paper has been divided into three parts for editorial reasons. This publication (Part 1) covers the recommendations for small molecule bioanalysis using LCMS. Part 2 (Hybrid LBA/LCMS, Electronic Laboratory Notebook and Regulatory Agencies' input) and Part 3 (Large molecules bioanalysis using LBA and Immunogenicity) will be published in the upcoming issues of Bioanalysis.
authors.affiliation: Pfizer, Pearl River, NY, USA.
authors.forename: Eric
authors.initials: E
authors.lastname: Fluhler
authors.forename: Roger
authors.initials: R
authors.lastname: Hayes
authors.forename: Fabio
authors.initials: F
authors.lastname: Garofolo
authors.forename: Isabelle
authors.initials: I
authors.lastname: Dumont
authors.forename: Olivier Le
authors.initials: OL
authors.lastname: Blaye
authors.forename: Mark
authors.initials: M
authors.lastname: Arnold
authors.forename: Surendra
authors.initials: S
authors.lastname: Bansal
authors.forename: Tom
authors.initials: T
authors.lastname: Verhaeghe
authors.forename: Amanda
authors.initials: A
authors.lastname: Wilson
authors.forename: Lauren
authors.initials: L
authors.lastname: Stevenson
authors.forename: Heather
authors.initials: H
authors.lastname: Myler
authors.forename: Ronald
authors.initials: R
authors.lastname: Bauer
authors.forename: Annik
authors.initials: A
authors.lastname: Bergeron
authors.forename: Mark
authors.initials: M
authors.lastname: Bustard
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Cai
authors.forename: Mary
authors.initials: M
authors.lastname: Carbone
authors.forename: Laura
authors.initials: L
authors.lastname: Cojocaru
authors.forename: Daksha
authors.initials: D
authors.lastname: Desai-Krieger
authors.forename: Jeff
authors.initials: J
authors.lastname: Duggan
authors.forename: Sam
authors.initials: S
authors.lastname: Haidar
authors.forename: Stacy
authors.initials: S
authors.lastname: Ho
authors.forename: Benno
authors.initials: B
authors.lastname: Ingelse
authors.forename: Noriko
authors.initials: N
authors.lastname: Katori
authors.forename: Ann
authors.initials: A
authors.lastname: Lévesque
authors.forename: Steve
authors.initials: S
authors.lastname: Lowes
authors.forename: Mark
authors.initials: M
authors.lastname: Ma
authors.forename: Katalina
authors.initials: K
authors.lastname: Mettke
authors.forename: Josée
authors.initials: J
authors.lastname: Michon
authors.forename: Adrien
authors.initials: A
authors.lastname: Musuku
authors.forename: Timothy
authors.initials: T
authors.lastname: Olah
authors.forename: Shefali
authors.initials: S
authors.lastname: Patel
authors.forename: Mark
authors.initials: M
authors.lastname: Rose
authors.forename: Gary
authors.initials: G
authors.lastname: Schultz
authors.forename: John
authors.initials: J
authors.lastname: Smeraglia
authors.forename: Neil
authors.initials: N
authors.lastname: Spooner
authors.forename: Bruce
authors.initials: B
authors.lastname: Stouffer
authors.forename: Faye
authors.initials: F
authors.lastname: Vazvaei
authors.forename: Jason
authors.initials: J
authors.lastname: Wakelin-Smith
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Jan
authors.initials: J
authors.lastname: Welink
authors.forename: Emma
authors.initials: E
authors.lastname: Whale
authors.forename: Eric
authors.initials: E
authors.lastname: Woolf
authors.forename: Li
authors.initials: L
authors.lastname: Xue
authors.forename: Tong-Yuan
authors.initials: TY
authors.lastname: Yang
mesh_terms: D001681:Biological Assay; D002853:Chromatography, Liquid / Q000379:methods*; D013058:Mass Spectrometry / Q000379:methods*