title: Evaluation of a protocol to reduce the incidence of neonatal calf diarrhoea on dairy herds.
abstract: Calf diarrhoea causes substantial economic losses in cattle herds worldwide. Neonatal calves are particularly sensitive to infections with enteropathogens. The present study focused on prevention against the main infectious causes of neonatal calf diarrhoea i.e. Escherichia coli, rota- and coronavirus, and Cryptosporidium parvum. Dairy herds (n=24) with a high percentage of neonatal calves scouring (>10%) were included and calves were sampled for the presence of these four enteropathogens. To decrease diarrhoea problems among neonatal calves, a standard protocol was tested on 13 herds (treatment group) where both C. parvum and either E. coli or rota- or coronavirus were identified as being involved, the other 11 herds served as control group. The protocol consisted of 2 points of action: preventive vaccination of dams against E. coli, rota- and coronavirus, and preventive administration of halofuginone lactate to newborn calves. The average percentage of calves suffering from neonatal diarrhoea (39.7% versus 14.3%, P<0.01) and the average percentage of faecal samples positive for C. parvum (34% versus 11%, P<0.05) differed significantly between control herds and treatment herds after implementation of the protocol. No significant differences between control and treatment group were observed in the percentage of calves excreting E. coli, rotavirus and coronavirus, both before and at the end of the trial. Furthermore, risk factors potentially associated with the development of neonatal calf scours were determined. Non-significant results were obtained for the effect of the protocol on duration of diarrhoea and the effect of the colostral IgG quantity on the risk of diarrhoea. Passive immunity transfer status of the calves, measured both before the onset and at the end of the study, were non-significant between groups.
authors.affiliation: Department of Reproduction, Obstetrics and Herd Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. Electronic address: vanessa.meganck@ugent.be.
authors.forename: V
authors.initials: V
authors.lastname: Meganck
authors.affiliation: MSD Animal Health, Lynx Binnenhof 5, 1200 Brussels, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Hoflack
authors.affiliation: Department of Reproduction, Obstetrics and Herd Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.
authors.forename: S
authors.initials: S
authors.lastname: Piepers
authors.affiliation: Department of Reproduction, Obstetrics and Herd Health, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Opsomer
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001428:Bacterial Vaccines / Q000008:administration & dosage*; D001530:Belgium / Q000453:epidemiology; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control*; D003126:Colostrum; D003332:Coronaviridae / Q000302:isolation & purification; D016785:Cryptosporidium parvum / Q000302:isolation & purification; D003612:Dairying; D003967:Diarrhea / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D015994:Incidence; D007407:Interviews as Topic; D016015:Logistic Models; D008297:Male; D009426:Netherlands / Q000453:epidemiology; D011247:Pregnancy; D052999:Quinazolinones / Q000008:administration & dosage*; D011897:Random Allocation; D012307:Risk Factors; D010880:Piperidines
chemical_list: D001428:Bacterial Vaccines; D052999:Quinazolinones; C010176:halofuginone; D010880:Piperidines
keywords: Colostrum; Dairy calf; Diarrhoea; Halofuginone; Vaccination