title: First case of Helicobacter pylori infection resistant to seven antibiotics in Iran.
abstract: Treatment of Helicobacter pylori infection with common antibiotics is typically recommended for several digestive conditions, including peptic ulcers. However, reports of resistant H. pylori isolates are increasing, and unfortunately, these do not respond to currently available therapeutic regimens. We report the case of a 31-year-old woman with two peptic ulcers in the duodenal antrum. An H. pylori strain was isolated, and tested for antibiotic resistance using agar dilution and disk diffusion. The isolated strain was found to be resistant to all seven antibiotics that were tested. Therefore, constant monitoring for antibiotic resistance should be performed prior to initiating antibiotic therapy.
authors.affiliation: Department of Medical Microbiology, Utrecht University, Utrecht, Netherlands.
authors.forename: Amin Talebi Bezmin
authors.initials: AT
authors.lastname: Abadi
authors.affiliation: Department of Bacteriology, Faculty of M edical Sciences, Tarbiat Modares University, Tehran, Iran.
authors.forename: Ashraf Mohabbati
authors.initials: AM
authors.lastname: Mobarez
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D052978:Disk Diffusion Antimicrobial Tests; D004352:Drug Resistance, Microbial; D004381:Duodenal Ulcer / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D016481:Helicobacter Infections / Q000188:drug therapy / Q000382:microbiology*; D016480:Helicobacter pylori / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D007492:Iran
chemical_list: D000900:Anti-Bacterial Agents