title: BK virus nephropathy in a pediatric patient after hematopoietic stem cell transplantation.
abstract: We report the case of a seven-yr-old Caucasian girl who presented with progressive deterioration of renal function 13 months after HSCT for myelodysplastic syndrome. BK virus nephropathy was suspected and confirmed. After reduction of immunosuppression and treatment with IVIG, leflunomide, ciprofloxacin, and cidofovir, clearance of BK virus from blood was achieved, and further progression or renal failure was prevented. We believe that BK virus nephropathy should be considered in cases of renal function deterioration in all immunocompromised patients.
authors.affiliation: Nephrology Department, Research and Clinical Institute for Pediatrics, the Pirogov Russian National Research Medical University, Moscow, Russia; Department of Clinical Diagnostics, the Rogachev Federal Research Center for Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
authors.forename: M
authors.initials: M
authors.lastname: Aksenova
authors.forename: V
authors.initials: V
authors.lastname: Tsetlina
authors.forename: E
authors.initials: E
authors.lastname: Gutovskaya
authors.forename: A
authors.initials: A
authors.lastname: Mitrofanova
authors.forename: D
authors.initials: D
authors.lastname: Balashov
authors.forename: A
authors.initials: A
authors.lastname: Maschan
mesh_terms: D001739:BK Virus; D002648:Child; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis* / Q000821:virology*; D027601:Polyomavirus Infections / Q000175:diagnosis*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000821:virology*; D014412:Tumor Virus Infections / Q000175:diagnosis*
keywords: BK polyomavirus; BK virus nephropathy; hematopoietic stem cell transplantation; renal insufficiency