title: Consensus guidelines for diagnosis, prophylaxis and management of Pneumocystis jirovecii pneumonia in patients with haematological and solid malignancies, 2014.
abstract: Pneumocystis jirovecii infection (PJP) is a common cause of pneumonia in patients with cancer-related immunosuppression. There are well-defined patients who are at risk of PJP due to the status of their underlying malignancy, treatment-related immunosuppression and/or concomitant use of corticosteroids. Prophylaxis is highly effective and should be given to all patients at moderate to high risk of PJP. Trimethoprim-sulfamethoxazole is the drug of choice for prophylaxis and treatment, although several alternative agents are available.
authors.affiliation: Department of Microbiology and Infectious Diseases, Royal Hobart Hospital, Hobart, Tasmania.
authors.forename: L
authors.initials: L
authors.lastname: Cooley
authors.forename: C
authors.initials: C
authors.lastname: Dendle
authors.forename: J
authors.initials: J
authors.lastname: Wolf
authors.forename: B W
authors.initials: BW
authors.lastname: Teh
authors.forename: S C
authors.initials: SC
authors.lastname: Chen
authors.forename: C
authors.initials: C
authors.lastname: Boutlis
authors.forename: K A
authors.initials: KA
authors.lastname: Thursky
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects; D019072:Antibiotic Prophylaxis; D032921:Consensus; D004334:Drug Administration Schedule; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology*; D009369:Neoplasms / Q000150:complications / Q000276:immunology*; D009894:Opportunistic Infections / Q000276:immunology / Q000382:microbiology* / Q000517:prevention & control*; D045363:Pneumocystis carinii / Q000472:pathogenicity*; D011020:Pneumonia, Pneumocystis / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000008:administration & dosage*
chemical_list: D000305:Adrenal Cortex Hormones; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
keywords: Pneumocystis carinii; Pneumocystis jirovecii; haematological malignancy; prophylaxis; solid-organ tumour; treatment