title: Relationships between stressful life events and impaired fasting glucose among left-behind farmers in rural China.
abstract: OBJECTIVE
  This study aims at examining the effects of stressful life events on risk of impaired fasting glucose among left-behind farmers in rural China.
  
  
  METHODS
  The study collected data about stressful life events, family history of diabetes, lifestyle, demographics and minimum anthropometrics from left-behind famers aged 40-70 years. Calculated life event index was applied to assess the combined effects of stressful life events experienced by the left-behind farmers and its association with impaired fasting glucose was estimated using binary logistic regression models.
  
  
  RESULTS
  The prevalence of abnormal fasting glucose was 61.4% by American Diabetes Association (ADA) standard and 32.4% by World Health Organization (WHO) standard. Binary logistic regression analysis revealed a coefficient of 0.033 (P<.001) by ADA standard or 0.028 (P<.001) by WHO standard between impaired fasting glucose and life event index. The overall odds ratios of impaired glucose for the second, third and fourth (highest) versus the first (lowest) quartile of life event index were 1.419 [95% CI=(1.173, 1.717)], 1.711 [95% CI=(1.413, 2.071)] and 1.957 [95% CI=(1.606, 2.385)] respectively by ADA standard. When more and more confounding factors were controlled for, these odds ratios remained statistically significant though decreased to a small extent.
  
  
  CONCLUSIONS
  The left-behind farmers showed over two-fold prevalence rate of pre-diabetes than that of the nation's average and their risk of impaired fasting glucose was positively associated with stressful life events in a dose-dependent way. Both the population studied and their life events merit special attention.
authors.affiliation: School of Health Service Management, Anhui Medical University, Hefei, China. Electronic address: 1010066583@qq.com.
authors.forename: Han
authors.initials: H
authors.lastname: Liang
authors.affiliation: School of Health Service Management, Anhui Medical University, Hefei, China; Department of Epidemiology and Statistics, School of Public Health, Anhui Medical University, Hefei, China. Electronic address: Xuchji1982@yahoo.com.cn.
authors.forename: Jing
authors.initials: J
authors.lastname: Cheng
authors.affiliation: School of Health Service Management, Anhui Medical University, Hefei, China. Electronic address: 1264854421@qq.com.
authors.forename: Xingrong
authors.initials: X
authors.lastname: Shen
authors.affiliation: School of Health Service Management, Anhui Medical University, Hefei, China. Electronic address: orangechenpl@yahoo.com.cn.
authors.forename: Penglai
authors.initials: P
authors.lastname: Chen
authors.affiliation: School of Health Service Management, Anhui Medical University, Hefei, China. Electronic address: 381378037@qq.com.
authors.forename: Guixian
authors.initials: G
authors.lastname: Tong
authors.affiliation: School of Health Service Management, Anhui Medical University, Hefei, China. Electronic address: jingchai82@sina.com.
authors.forename: Jing
authors.initials: J
authors.lastname: Chai
authors.affiliation: Lu'an Center for Diseases Prevention and Control, Lu'an, China. Electronic address: 853571123@qq.com.
authors.forename: Kaichun
authors.initials: K
authors.lastname: Li
authors.affiliation: Lu'an Center for Diseases Prevention and Control, Lu'an, China. Electronic address: 1252509750@qq.com.
authors.forename: Shaoyu
authors.initials: S
authors.lastname: Xie
authors.affiliation: Lu'an Center for Diseases Prevention and Control, Lu'an, China. Electronic address: 1214984721@qq.com.
authors.forename: Yong
authors.initials: Y
authors.lastname: Shi
authors.affiliation: School of Health Service Management, Anhui Medical University, Hefei, China. Electronic address: dbwang@vip.sina.com.
authors.forename: Debin
authors.initials: D
authors.lastname: Wang
authors.affiliation: Department of Epidemiology and Statistics, School of Public Health, Anhui Medical University, Hefei, China. Electronic address: yhsun@sina.com.
authors.forename: Yehuan
authors.initials: Y
authors.lastname: Sun
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D002681:China / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000097:blood / Q000517:prevention & control; D005215:Fasting; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000453:epidemiology* / Q000517:prevention & control; D008016:Life Change Events; D008019:Life Style; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D012307:Risk Factors; D012424:Rural Population / Q000706:statistics & numerical data*
chemical_list: D001786:Blood Glucose
keywords: Diabetes; Glucose; Life events; Odds ratio; Regression