title: A general synthesis of fluoroalkylated alkenes by palladium-catalyzed Heck-type reaction of fluoroalkyl bromides.
abstract: An efficient palladium-catalyzed Heck-type reaction of fluoroalkyl halides, including perfluoroalkyl bromides, trifluoromethyl iodides, and difluoroalkyl bromides, has been developed. The reaction proceeds under mild reaction conditions with high efficiency and broad substrate scope, and provides a general and straightforward access to fluoroalkylated alkenes which are of interest in life and material sciences.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032 (China).
authors.forename: Zhang
authors.initials: Z
authors.lastname: Feng
authors.forename: Qiao-Qiao
authors.initials: QQ
authors.lastname: Min
authors.forename: Hai-Yang
authors.initials: HY
authors.lastname: Zhao
authors.forename: Ji-Wei
authors.initials: JW
authors.lastname: Gu
authors.forename: Xingang
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D001965:Bromides / Q000737:chemistry*; D002384:Catalysis; D005461:Fluorine / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry; D014966:Xanthenes / Q000737:chemistry
chemical_list: D000475:Alkenes; D001965:Bromides; D010720:Phosphines; D014966:Xanthenes; D005461:Fluorine; D010165:Palladium; C519861:xantphos
keywords: alkenes; fluoroalkylation; halides; palladium; synthetic methods