title: [Development of scleroderma renal crisis in a patient with undiagnosed scleroderma].
abstract: Less than 10% of the patients with systemic scleroderma develop renal crisis, i.e. acute renal failure and severe hypertension in most cases. Kidney biopsy shows hypertensive arteriolar changes. This complication was lethal until treatment with captopril was introduced in 1976. Since that time the survival of the patients has improved. If treatment is started early, further deteoriation of the kidney may be prevented.
authors.affiliation: Nefrologisk Afdeling, Hillerød Hospital, Dyrehavevej 29, 4900 Hillerød. kristine.lindhard@gmail.com.
authors.forename: Kristine Lindhard
authors.initials: KL
authors.lastname: Madsen
authors.forename: Alastair
authors.initials: A
authors.lastname: Hansen
authors.forename: Poul
authors.initials: P
authors.lastname: Halberg
authors.forename: Susanne
authors.initials: S
authors.lastname: Ullman
mesh_terms: D058186:Acute Kidney Injury / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use; D004656:Enalapril / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D045743:Scleroderma, Diffuse / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology
chemical_list: D000959:Antihypertensive Agents; D004656:Enalapril