title: Iron catalyzed oxidative assembly of N-heteroaryl and aryl metal reagents using oxygen as an oxidant.
abstract: An equivalent amount of N-heteroaryl and aryl Grignard or lithium reagents, after mediation by an equivalent of titanate, was facilely coupled to furnish N-heteroaryl-aryl compounds under the catalysis of FeCl3/TMEDA at ambient temperature using oxygen as an oxidant. Most of the common N-heteroaryls were all good candidates, and thus provided a general, green and pratical protocol for the flexible construction of various N-heteroaryl-aryl structures.
authors.affiliation: College of Chemistry, Beijing Normal University, Beijing, 100875, China. xinfangduan@vip.163.com.
authors.forename: Kun Ming
authors.initials: KM
authors.lastname: Liu
authors.forename: Lian Yan
authors.initials: LY
authors.lastname: Liao
authors.forename: Xin Fang
authors.initials: XF
authors.lastname: Duan
mesh_terms: D002384:Catalysis; D007501:Iron / Q000737:chemistry*; D008670:Metals / Q000737:chemistry; D015394:Molecular Structure; D009538:Nicotine / Q000737:chemistry; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*
chemical_list: D008670:Metals; D009538:Nicotine; D007501:Iron; D010100:Oxygen