title: Can chatter between microbes prevent cholera?
abstract: Tackling the global rise in antibiotic resistance requires new therapies against infectious microbes. A recent microbiome study identified commensal gut bacteria that reduce colonisation by the cholera pathogen, Vibrio cholerae. This antagonistic interaction might be mediated by quorum sensing, suggesting that these natural microbe-microbe interactions can help prevent infectious disease.
authors.affiliation: Instituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
authors.forename: Jessica A
authors.initials: JA
authors.lastname: Thompson
authors.affiliation: Instituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
authors.forename: Rita Almeida
authors.initials: RA
authors.lastname: Oliveira
authors.affiliation: Instituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal; Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, 2780-157 Oeiras, Portugal. Electronic address: kxavier@igc.gulbenkian.pt.
authors.forename: Karina B
authors.initials: KB
authors.lastname: Xavier
mesh_terms: D000818:Animals; D002771:Cholera / Q000382:microbiology*; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D008297:Male; D064307:Microbiota / Q000502:physiology*; D045857:Ruminococcus / Q000502:physiology*; D014734:Vibrio cholerae / Q000472:pathogenicity* / Q000502:physiology*
keywords: AI-2; LuxS; bacterial signalling; cell–cell communication; microbiota; quorum sensing