title: Functional foods and cardiometabolic diseases*  International Task Force for Prevention of Cardiometabolic Diseases.
abstract: Mounting evidence supports the hypothesis that functional foods containing physiologically-active components may be healthful. Longitudinal cohort studies have shown that some food classes and dietary patterns are beneficial in primary prevention, and this has led to the identification of putative functional foods. This field, however, is at its very beginning, and additional research is necessary to substantiate the potential health benefit of foods for which the diet-health relationships are not yet scientifically validated. It appears essential, however, that before health claims are made for particular foods, in vivo randomized, double-blind, placebo controlled trials of clinical end-points are necessary to establish clinical efficacy. Since there is need for research work aimed at devising personalized diet based on genetic make-up, it seems more than reasonable the latter be modeled, at present, on the Mediterranean diet, given the large body of evidence of its healthful effects. The Mediterranean diet is a nutritional model whose origins go back to the traditional dietadopted in European countries bordering the Mediterranean sea, namely central and southern Italy, Greece and Spain; these populations have a lower incidence of cardiovascular diseases than the North American ones, whose diet is characterized by high intake of animal fat. The meeting in Naples and this document both aim to focus on the changes in time in these two different models of dietary habits and their fall out on public health.
authors.forename: G
authors.initials: G
authors.lastname: Assmann
authors.forename: P
authors.initials: P
authors.lastname: Buono
authors.forename: A
authors.initials: A
authors.lastname: Daniele
authors.forename: E
authors.initials: E
authors.lastname: Della Valle
authors.forename: E
authors.initials: E
authors.lastname: Farinaro
authors.forename: G
authors.initials: G
authors.lastname: Ferns
authors.forename: V
authors.initials: V
authors.lastname: Krogh
authors.forename: D
authors.initials: D
authors.lastname: Kromhout
authors.forename: L
authors.initials: L
authors.lastname: Masana
authors.forename: J
authors.initials: J
authors.lastname: Merino
authors.forename: G
authors.initials: G
authors.lastname: Misciagna
authors.forename: S
authors.initials: S
authors.lastname: Panico
authors.forename: G
authors.initials: G
authors.lastname: Riccardi
authors.forename: A A
authors.initials: AA
authors.lastname: Rivellese
authors.forename: F
authors.initials: F
authors.lastname: Rozza
authors.forename: F
authors.initials: F
authors.lastname: Salvatore
authors.forename: V
authors.initials: V
authors.lastname: Salvatore
authors.forename: S
authors.initials: S
authors.lastname: Stranges
authors.forename: M
authors.initials: M
authors.lastname: Trevisan
authors.forename: B
authors.initials: B
authors.lastname: Trimarco
authors.forename: C
authors.initials: C
authors.lastname: Vetrani
mesh_terms: D000818:Animals; D031204:Caloric Restriction; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000517:prevention & control*; D004034:Diet Surveys; D038441:Diet, Mediterranean; D044127:Epigenesis, Genetic; D005247:Feeding Behavior; D055951:Functional Food; D006801:Humans; D054647:Nutrigenomics