title: Jorge Lobo's disease: a case of keloidal blastomycosis (lobomycosis) in a nonendemic area.
abstract: Lobomycosis or lacaziosis is a chronic subcutaneous fungal infection, caused by the fungus Lacazia loboi, which is phylogenetically related to Coccidioides, Blastomyces, Histoplasma, and Paracoccidioides. The disease was first recognized in 1931 by Jorge Lobo, who found the disease to be a keloidal blastomycosis and named it Jorge Lobo's disease. This case was perplexing initially as this fungal infection is very uncommon in the USA. However, with the ever-increasing frequency of international travel, many more cases of lobomycosis have been diagnosed in areas of nonendemicity, such as the USA, Europe, and South Africa. The clinical histories of such imported fungal infections often illustrate their long latency periods. In lobomycosis, the onset of the disease is usually insidious and often difficult to document. We describe a case of a New York resident who presented with multiple skin nodules over both his arms and forearms, and was subsequently diagnosed with Jorge Lobo's disease. The case, diagnosis, histopathologic findings, complication, and management of this rare clinical disease are discussed.
authors.affiliation: Department of Family Medicine, The Brooklyn Hospital Center, Brooklyn, NY, USA.
authors.forename: Rezina
authors.initials: R
authors.lastname: Arju
authors.forename: Jiten P
authors.initials: JP
authors.lastname: Kothadia
authors.affiliation: Department of Internal Medicine, The Brooklyn Hospital Center, Brooklyn, NY, USA.
authors.forename: Monica
authors.initials: M
authors.lastname: Kaminski
authors.affiliation: Department of Family Medicine, The Brooklyn Hospital Center, Brooklyn, NY, USA.
authors.forename: Sherly
authors.initials: S
authors.lastname: Abraham
authors.affiliation: Director, Division of Anatomic Pathology, Department of Pathology and Laboratory Medicine, The Brooklyn Hospital Center, 121 DeKalb Avenue, Brooklyn, NY 11201, USA.
authors.forename: Shah
authors.initials: S
authors.lastname: Giashuddin
keywords: Jorge Lobo’s disease; fungal infections; keloidal blastomycosis; mycoses