title: Association of sialolithiasis with cholelithiasis: A population-based study.
abstract: BACKGROUND
  The purpose of this study was to evaluate the association between cholelithiasis and developing sialolithiasis using a population-based coverage database.
  
  
  METHODS
  The data for this study were sourced from the Taiwan Longitudinal Health Insurance Database. We included 745 subjects with sialolithiasis as cases and 3725 sex-matched and age-matched subjects without sialolithiasis as controls.
  
  
  RESULTS
  Chi-square test revealed a significant difference in the prevalence of prior cholelithiasis between the cases and controls (8.6% vs 4.1%; p < .001). Furthermore, conditional logistic regression analysis indicated that the odds ratio (OR) of prior cholelithiasis for the cases was 2.19 (95% confidence interval [CI] = 1.62-2.98) when compared with the controls after adjusting for monthly income, geographic location, urbanization level, and tobacco use disorder. The adjusted OR of prior cholelithiasis for cases was 2.20 (95% CI = 1.46-3.33) and 2.15 (95% CI = 1.38-3.42) than controls for men and women, respectively.
  
  
  CONCLUSIONS
  This study demonstrates an association between sialolithiasis and cholelithiasis.
authors.affiliation: Department of Otolaryngology, Taipei Medical University Hospital, Taipei, Taiwan.|Department of Otolaryngology, School of Medicine, Taipei Medical University, Taipei, Taiwan.
authors.forename: Shih-Han
authors.initials: SH
authors.lastname: Hung
authors.affiliation: Sleep Research Center, Taipei Medical University, Taipei, Taiwan.
authors.forename: Herng-Ching
authors.initials: HC
authors.lastname: Lin
authors.affiliation: Department of Otolaryngology, School of Medicine, Taipei Medical University, Taipei, Taiwan.|Department of Otorhinolaryngology, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Chin-Hui
authors.initials: CH
authors.lastname: Su
authors.affiliation: Sleep Research Center, Taipei Medical University, Taipei, Taiwan.|Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan.|School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
authors.forename: Shiu-Dong
authors.initials: SD
authors.lastname: Chung
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002769:Cholelithiasis / Q000150:complications* / Q000453:epidemiology; D016208:Databases, Factual; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D015494:Salivary Gland Calculi / Q000453:epidemiology / Q000209:etiology*; D013624:Taiwan / Q000453:epidemiology
keywords: case-control study; cholelithiasis; epidemiology; salivary gland; sialolithiasis