title: Response of Caenorhabditis elegans to wireless devices radiation exposure.
abstract: OBJECTIVE
  To examine the impact of electromagnetic radiation, produced by GSM (Global System for Mobile communications) mobile phones, Wi-Fi (Wireless-Fidelity) routers and wireless DECT (Digital Enhanced Cordless Telecommunications) phones, on the nematode Caenorhabditis elegans.
  
  
  METHODS
  We exposed synchronized populations, of different developmental stages, to these wireless devices at E-field levels below ICNIRP's (International Commission on Non-Ionizing Radiation Protection) guidelines for various lengths of time. WT (wild-type) and aging- or stress-sensitive mutant worms were examined for changes in growth, fertility, lifespan, chemotaxis, short-term memory, increased ROS (Reactive Oxygen Species) production and apoptosis by using fluorescent marker genes or qRT-PCR (quantitative Reverse Transcription-Polymerase Chain Reaction).
  
  
  RESULTS
  No statistically significant differences were found between the exposed and the sham/control animals in any of the experiments concerning lifespan, fertility, growth, memory, ROS, apoptosis or gene expression.
  
  
  CONCLUSIONS
  The worm appears to be robust to this form of (pulsed) radiation, at least under the exposure conditions used.
authors.affiliation: Basic Research II, Biomedical Research Foundation of the Academy of Athens , Athens , Greece.
authors.forename: Michael K
authors.initials: MK
authors.lastname: Fasseas
authors.forename: Adamantia F
authors.initials: AF
authors.lastname: Fragopoulou
authors.forename: Areti K
authors.initials: AK
authors.lastname: Manta
authors.forename: Aikaterini
authors.initials: A
authors.lastname: Skouroliakou
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Vekrellis
authors.forename: Lukas H
authors.initials: LH
authors.lastname: Margaritis
authors.forename: Popi
authors.initials: P
authors.lastname: Syntichaki
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D017209:Apoptosis / Q000528:radiation effects; D017173:Caenorhabditis elegans / Q000254:growth & development / Q000502:physiology / Q000528:radiation effects*; D040421:Cell Phone; D002633:Chemotaxis / Q000528:radiation effects; D004574:Electromagnetic Fields / Q000009:adverse effects*; D005260:Female; D005298:Fertility / Q000528:radiation effects; D015870:Gene Expression / Q000528:radiation effects; D017238:Genes, Helminth / Q000528:radiation effects; D006128:Growth / Q000528:radiation effects; D008136:Longevity / Q000528:radiation effects; D008297:Male; D008570:Memory, Short-Term / Q000528:radiation effects; D009410:Nerve Degeneration / Q000209:etiology; D011853:Radiobiology; D017382:Reactive Oxygen Species / Q000378:metabolism; D059015:Wireless Technology
chemical_list: D017382:Reactive Oxygen Species
keywords: Caenorhabditis elegans; DECT; GSM; Wi-Fi; non-ionizing radiation; stress