title: Epidemiology and antibiotic susceptibility of aerococci in urinary cultures.
abstract: In this study, we present population-based data regarding the prevalence of aerococci in clinical urinary samples. During a 3-month period, all aerococcal isolates from urinary samples from 2 clinical microbiology laboratories were collected. We identified 64 Aerococcus urinae isolates and 40 Aerococcus sanguinicola isolates, which correlates with an incidence of 33 cases of aerococcal bacteriuria per 100,000 inhabitants per year. The median age was 83years for all patients with aerococcal bacteriuria, which was significantly higher than for patients with Escherichia coli or Enterococcus faecalis bacteriuria. Sex was almost equally distributed between men and women with aerococcal bacteriuria, whereas females dominated in E. coli bacteriuria. The aerococcal isolates displayed low MICs for ampicillin, cefalotin, mecillinam, and nitrofurantoin. Most A. sanguinicola isolates were resistant to ciprofloxacin, whereas most A. urinae isolates had low MICs. Clinical studies are needed to establish clinical breakpoints and optimal treatment.
authors.affiliation: Division of Laboratory Medicine, Department of Clinical Microbiology, Sölvegatan 23, 221 85, Lund, Sweden; Division of Infection Medicine, Department of Clinical Sciences, Lund University, BMC B14, Tornavägen 10, 221 84 Lund, Sweden. Electronic address: erik.senneby@med.lu.se.
authors.forename: Erik
authors.initials: E
authors.lastname: Senneby
authors.affiliation: Division of Laboratory Medicine, Department of Clinical Microbiology, Sölvegatan 23, 221 85, Lund, Sweden.
authors.forename: Ann-Cathrine
authors.initials: AC
authors.lastname: Petersson
authors.affiliation: Division of Infection Medicine, Department of Clinical Sciences, Lund University, BMC B14, Tornavägen 10, 221 84 Lund, Sweden.
authors.forename: Magnus
authors.initials: M
authors.lastname: Rasmussen
mesh_terms: D000293:Adolescent; D000328:Adult; D056570:Aerococcus / Q000187:drug effects* / Q000302:isolation & purification*; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015995:Prevalence; D017678:Sex Distribution; D014552:Urinary Tract Infections / Q000453:epidemiology* / Q000382:microbiology; D014556:Urine / Q000382:microbiology*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents
keywords: Aerococcus sanguinicola; Aerococcus urinae; Antimicrobial susceptibility testing; Epidemiology; Urinary tract infection