title: Outcomes from the Body & Soul Clinical Trials Project: a university-church partnership to improve African American enrollment in a clinical trial registry.
abstract: OBJECTIVE
  Historically, African Americans have been underrepresented in clinical trials (CTs) compared to whites. A growing number of research institutions have created CT registries to match volunteers with appropriate studies. In a sample of 745 African Americans from 16 churches, we tested the impact of a culturally tailored intervention aimed at increasing enrollment in a university-based CT registry.
  
  
  METHODS
  Half of the churches received a culturally tailored CT education program (intervention) and half of the churches received a program about healthy eating (comparison). The main outcomes were the odds of post-test self-reported enrollment and verified enrollment. Using linear regression, post-test willingness to participate in a CT was also assessed.
  
  
  RESULTS
  Odds of verified enrollment were higher in the intervention than comparison group (OR=2.95, 95% CI: 1.33-6.5, p=0.01). Post-test self-reported enrollment in the registry was also higher among the intervention group than comparison group members (OR=1.94, 95% CI: 1.08-3.47, p=0.03). Willingness to participate in a future CT was higher in the intervention group (β=0.74, p=0.02).
  
  
  CONCLUSIONS
  A culturally tailored education program about CTs can increase enrollment of African Americans in a university-based clinical trials registry.
  
  
  CONCLUSIONS
  Community engagement and health education workshops may improve minority CT enrollment over time.
authors.affiliation: Center for Clinical Management Research, Department of Veterans Affairs Ann Arbor, Ann Arbor, USA. Electronic address: alangfor@umich.edu.
authors.forename: Aisha T
authors.initials: AT
authors.lastname: Langford
authors.affiliation: Department of Health Behavior & Health Education, University of Michigan, Ann Arbor, USA.
authors.forename: Ken
authors.initials: K
authors.lastname: Resnicow
authors.affiliation: Department of Behavioral Sciences & Health Education, Rollins School of Public Health of Emory University, Atlanta, USA.
authors.forename: Derrick D
authors.initials: DD
authors.lastname: Beasley
mesh_terms: D000328:Adult; D001741:Black or African American / Q000193:education* / Q000523:psychology; D035843:Biomedical Research; D002835:Christianity; D002986:Clinical Trials as Topic; D055812:Community-Based Participatory Research; D005260:Female; D006266:Health Education / Q000379:methods*; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008824:Michigan; D012042:Registries; D014495:Universities
keywords: African Americans; Clinical trials; Enrollment; Minority; Registry; Research