title: A case of intoxication due to a highly cytotoxic Bacillus cereus strain isolated from cooked chicken.
abstract: Outbreaks of Bacillus cereus infection/intoxication are not commonly reported because symptoms are often mild, and the disease is self-limiting. However, hypervirulent strains increase health risks. We report a case, which occurred in Argentina, of severe food poisoning illness on a healthy adult woman associated to B. cereus strain MVL2011. The studied strain was highly cytotoxic, showed high ability to detach Caco-2 cells and was positive for the hblA, hblB, and hblC genes of the hbl complex, bceT, entS and ces. As it is considered that B. cereus emetic cluster evolved from a panmictic population of diarrheal strains, B. cereus MVL2011 could constitute an intermediate strain between diarrheal and emetic strains.
authors.affiliation: Unidad de Bacteriología, Centro de Investigaciones de Fitopatología, Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, cc 31, Calle 60 y 119, 1900 La Plata, Argentina. Electronic address: rodrika@biol.unlp.edu.ar.
authors.forename: Ana C
authors.initials: AC
authors.lastname: López
authors.affiliation: Centro de Investigación y Desarrollo en Criotecnología de Alimentos (CONICET. La Plata), Calle 47 y 116-B1900AJI, La Plata, Argentina; Área Farmacia, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Calle 47 y 115-B1900AJI, La Plata, Argentina. Electronic address: jm@biol.unlp.edu.ar.
authors.forename: Jessica
authors.initials: J
authors.lastname: Minnaard
authors.affiliation: Centro de Investigación y Desarrollo en Criotecnología de Alimentos (CONICET. La Plata), Calle 47 y 116-B1900AJI, La Plata, Argentina; Cátedra de Microbiología, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Calle 47 y 115-B1900AJI, La Plata, Argentina. Electronic address: pfp@biol.unlp.edu.ar.
authors.forename: Pablo F
authors.initials: PF
authors.lastname: Pérez
authors.affiliation: Unidad de Bacteriología, Centro de Investigaciones de Fitopatología, Facultad de Ciencias Agrarias y Forestales, Universidad Nacional de La Plata, cc 31, Calle 60 y 119, 1900 La Plata, Argentina. Electronic address: alippi@biol.unlp.edu.ar.
authors.forename: Adriana M
authors.initials: AM
authors.lastname: Alippi
mesh_terms: D000328:Adult; D000818:Animals; D001409:Bacillus cereus / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D018938:Caco-2 Cells; D002645:Chickens; D003296:Cooking; D004768:Enterotoxins / Q000235:genetics / Q000378:metabolism; D005260:Female; D005506:Food Contamination / Q000032:analysis*; D005517:Foodborne Diseases / Q000382:microbiology*; D006801:Humans; D008460:Meat / Q000032:analysis / Q000382:microbiology*
chemical_list: D001426:Bacterial Proteins; D004768:Enterotoxins
keywords: Bacillus cereus; Detachment; Epithelial cells; Food poisoning; Genes; Necrosis; Virulence