title: T1 mapping: technique and applications.
abstract: T1 mapping, one form of tissue characterization performed with a parametric approach, has been gaining rapid popularity, as different sequences have been developed to integrate image acquisition into a clinical routine. This technique allows fast progression from the basics of sequence development to its application in normal individuals and distinct diseases, sometimes overriding the more gradual steps taken with other cardiovascular magnetic resonance advances. In this review, the state-of-the-art in T1 mapping is examined, focusing on its techniques, sequences, comparison of native versus extracellular volume fraction measurements, and the current and future clinical applications of the method.
authors.affiliation: Cardiovascular Imaging Center, Jose Michel Kalaf Research Institute, Av Jose de Souza Campo 840, Campinas, Sao Paulo 13025260, Brazil.
authors.forename: Juliano Lara
authors.initials: JL
authors.lastname: Fernandes
authors.affiliation: CMR and CCT Section, Cardiology Department, Heart Institute (InCor), University of Sao Paulo Medical School, Av Dr Eneas de Carvalho Aguiar 44-Andar AB, São Paulo, Sao Paulo 05403-900, Brazil. Electronic address: rochitte@incor.usp.br.
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: Rochitte
mesh_terms: D000465:Algorithms; D006331:Heart Diseases / Q000175:diagnosis*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: Cardiovascular magnetic resonance; Fibrosis; Parametric mapping; T1