title: Bugs and food: a recipe for cancer?
abstract: Obesity and the associated state of subchronic inflammation are risk factors for numerous pathologies, including carcinogenesis. Recently, Schulz et al. (2014) demonstrated that high-fat diet-induced intestinal dysbiosis promotes cancer development in K-ras(G12Dint) mice without inducing obesity or mucosal inflammation, positioning microbial activities as a central component of diet-induced carcinogenesis.
authors.affiliation: Department of Medicine, University of Florida, Gainesville, FL 32610, USA.
authors.forename: Christina L
authors.initials: CL
authors.lastname: Ohland
authors.affiliation: Department of Medicine, University of Florida, Gainesville, FL 32610, USA; Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL 32610, USA. Electronic address: christian.jobin@medicine.ufl.edu.
authors.forename: Christian
authors.initials: C
authors.lastname: Jobin
mesh_terms: D000818:Animals; D063646:Carcinogenesis / Q000187:drug effects*; D059305:Diet, High-Fat / Q000009:adverse effects*; D004041:Dietary Fats / Q000009:adverse effects*; D064806:Dysbiosis / Q000139:chemically induced* / Q000382:microbiology*; D007414:Intestinal Neoplasms / Q000382:microbiology*; D009765:Obesity
chemical_list: D004041:Dietary Fats