title: Serological survey of canine leptospirosis in three countries of tropical Africa: Sudan, Gabon and Ivory Coast.
abstract: A cross-sectional survey was conducted to estimate the presence of leptospiral antibodies among 475 dogs from three countries of tropical Africa: Sudan (n=62), Gabon (n=255) and Ivory Coast (n=158). Sixteen reference strains belonging to seven serogroups were used as antigen in the microscopic agglutination test. Overall, considering titres ≥1:40, 453 samples were positive towards one or several serovars of pathogenic leptospires. Focusing on high titres, i.e. ≥1:320, the seroprevalence was 40.8%. In Gabon, the seroprevalence was higher in rural areas than in an urban environment (p<0.001). In Ivory Coast, the seroprevalence for serogroups Icterohaemorrhagiae and Canicola was not statistically different according to the vaccinal status. Predominant serogroups varied according to the countries but Grippotyphosa and Sejroë were the most common, while Icterohaemorragiae and Canicola were dominant in Sudan. In these three countries, dogs are heavily exposed to pathogenic Leptospira and humans living in the same environment are also at risk of infection.
authors.affiliation: Groupe de Travail en Épidémiologie Animale du Service de Santé des Armées, BCRM Toulon, BP 95, 83800 Toulon Cedex 9, France. Electronic address: cedric.roqueplo@wanadoo.fr.
authors.forename: Cédric
authors.initials: C
authors.lastname: Roqueplo
authors.affiliation: Groupe de Travail en Épidémiologie Animale du Service de Santé des Armées, BCRM Toulon, BP 95, 83800 Toulon Cedex 9, France.
authors.forename: Jean-Lou
authors.initials: JL
authors.lastname: Marié
authors.affiliation: Département des Maladies Infectieuses, Ecole Nationale Vétérinaire de Nantes, ONIRIS, Route de Gachet, BP 40706, 44307 Nantes Cedex 3, France.
authors.forename: Geneviève
authors.initials: G
authors.lastname: André-Fontaine
authors.affiliation: Laboratoire des Leptospires, Equipe PERS, VetAgro Sup, Campus Vétérinaire de Lyon, 1 Av Bourgelat, 69280 Marcy l'Etoile, France.
authors.forename: Angeli
authors.initials: A
authors.lastname: Kodjo
authors.affiliation: Groupe de Travail en Épidémiologie Animale du Service de Santé des Armées, BCRM Toulon, BP 95, 83800 Toulon Cedex 9, France; Unité de Recherche sur les Maladies Infectieuses et Tropicales Émergentes, IHU Méditerranée Infection, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France.
authors.forename: Bernard
authors.initials: B
authors.lastname: Davoust
mesh_terms: D000372:Agglutination Tests; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D007560:Cote d'Ivoire; D003430:Cross-Sectional Studies; D004283:Dog Diseases / Q000453:epidemiology / Q000276:immunology* / Q000382:microbiology; D004285:Dogs; D005681:Gabon; D007919:Leptospira / Q000276:immunology*; D007922:Leptospirosis / Q000453:epidemiology / Q000276:immunology / Q000662:veterinary*; D016036:Seroepidemiologic Studies; D013397:Sudan
chemical_list: D000907:Antibodies, Bacterial
keywords: Africa; Dog; Epidemiology; Gabon; Ivory Coast; Leptospira spp.; Leptospirosis; Sudan