title: DRESS syndrome secondary to ibuprofen as a cause of hyperacute liver failure.
abstract: Acute liver failure has a high mortality and its most frequent cause in Spain is viral infection. In this article, we present a case of fulminant liver failure. The failure is secondary to an idiosyncratic reaction to ibuprofen, an entity included in the DRESS syndrome. This syndrome plays a key role in the differential diagnosis of acute liver failure, since its unfortunate course often requires liver transplantation as the only useful therapeutic weapon. This case illustrates the need for an efficient coordination between hospitals as a key factor for improving the prognosis.
authors.forename: Valentín
authors.initials: V
authors.lastname: Roales-Gómez
authors.forename: Aída Isabel
authors.initials: AI
authors.lastname: Molero
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Pérez-Amarilla
authors.forename: Sergio
authors.initials: S
authors.lastname: Casabona-Francés
authors.forename: Enrique
authors.initials: E
authors.lastname: Rey-Díaz-Rubio
authors.forename: Mercedes
authors.initials: M
authors.lastname: Catalán
authors.forename: Francisco
authors.initials: F
authors.lastname: Vanaclocha
authors.forename: Francisco
authors.initials: F
authors.lastname: Colina
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D063926:Drug Hypersensitivity Syndrome / Q000150:complications*; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects*; D017114:Liver Failure, Acute / Q000209:etiology*; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007052:Ibuprofen