title: Extensive pulmonary alveolar microlithiasis.
abstract: Pulmonary alveolar microlithiasis is a rare pulmonary disorder that is caused by abnormal sodium-dependent phosphate co-transporter from the mutation of SLC34A2 gene, leading to accumulation of microliths in the alveoli. We report the extensive pulmonary alveolar microlithiasis in an elderly woman who presented with progressive dyspnea for 2 months. Chest radiograph revealed diffuse pulmonary calcification. Tissue histopathology from open lung biopsy demonstrated widespread intra-alveolar laminated calcium deposits compatible with pulmonary alveolar microlithiasis.
authors.affiliation: Division of Respiratory Diseases and Tuberbulosis, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok, Thailand.
authors.forename: Nuttapol
authors.initials: N
authors.lastname: Rittayamai
authors.affiliation: Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok, Thailand.
authors.forename: Nisa
authors.initials: N
authors.lastname: Muangman
authors.affiliation: Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University Bangkok, Thailand.
authors.forename: Ruchira
authors.initials: R
authors.lastname: Ruangchira-Urai
keywords: Alveolar microlithiasis; SLC34A2 gene; computed tomography of chest; hypoxemia; pulmonary calcification