title: Stimuli-responsive polymers for anti-cancer drug delivery.
abstract: Stimuli-responsive polymers are an important component for preparation of stimuli-responsive drug delivery systems with less side effects and improved efficacy for cancer treatment. There are endogenous stimuli and exogenous stimuli which can be explored. Here we review the developments in both endogenous stimuli- including redox-/pH-/enzyme-responsive polymers and exogenous stimuli- including thermo-/photo- and ultrasound-responsive polymers for delivery of anti-cancer drugs.
authors.affiliation: Institute of Materials Research and Engineering, A*STAR, 3 Research Link, Singapore 117602.
authors.forename: Weiren
authors.initials: W
authors.lastname: Cheng
authors.affiliation: Institute of Materials Research and Engineering, A*STAR, 3 Research Link, Singapore 117602.
authors.forename: Liuqun
authors.initials: L
authors.lastname: Gu
authors.affiliation: Institute of Materials Research and Engineering, A*STAR, 3 Research Link, Singapore 117602.
authors.forename: Wei
authors.initials: W
authors.lastname: Ren
authors.affiliation: Institute of Materials Research and Engineering, A*STAR, 3 Research Link, Singapore 117602. Electronic address: ye-liu@imre.a-star.edu.sg.
authors.forename: Ye
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry*; D005978:Glutathione / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D009369:Neoplasms / Q000188:drug therapy; D010084:Oxidation-Reduction; D011108:Polymers / Q000737:chemistry*; D013696:Temperature
chemical_list: D000970:Antineoplastic Agents; D004337:Drug Carriers; D011108:Polymers; D005978:Glutathione
keywords: cancer therapy; drug delivery; encapsulation; polymer; stimuli-responsive