title: Electrospun TiO₂ nanofibers decorated Ti substrate for biomedical application.
abstract: Various TiO2 nanofibers on Ti surface have been fabricated via electrospinning and calcination. Due to different elaboration conditions the electrospun fibers have different surface feature morphologies, characterized by scanning electronic microscopy, surface roughness, and contact angle measurements. The results have indicated that the average sample diameters are between 32 and 44 nm, roughness between 61 and 416 nm, and all samples are hydrophilic. As biological evaluation, cell culture with MG63 cell line originally derived from a human osteosarcoma was performed and correlation between nanofibers elaboration, properties and cell response was established. The cell adherence and growth are more evident on Ti samples with more aligned fibers, higher roughness and strong hydrophilic character and such fibers have been elaborated with a high speed rotating cylinder collector, confirming the idea that nanostructure elaboration conditions guide the cells' growth.
authors.affiliation: Åbo Akademi University, Process Chemistry Centre, Laboratory of Analytical Chemistry, Biskopsgatan 8, Åbo-Turku FI-20500, Finland; Politehnica University Bucharest, Faculty of Applied Chemistry and Materials Science, Department of General Chemistry, 1-7 Polizu, Bucharest Ro-011061, Romania.
authors.forename: Cristina
authors.initials: C
authors.lastname: Dumitriu
authors.affiliation: Politehnica University Bucharest, Faculty of Applied Chemistry and Materials Science, Department of General Chemistry, 1-7 Polizu, Bucharest Ro-011061, Romania.
authors.forename: Andrei Bogdan
authors.initials: AB
authors.lastname: Stoian
authors.affiliation: Institute of Cellular Biology and Pathology "Nicolae Simionescu", 8 B. P. Hasdeu, district 5, Bucharest Ro-050568, Romania.
authors.forename: Irina
authors.initials: I
authors.lastname: Titorencu
authors.affiliation: Institute of Cellular Biology and Pathology "Nicolae Simionescu", 8 B. P. Hasdeu, district 5, Bucharest Ro-050568, Romania.
authors.forename: Vasile
authors.initials: V
authors.lastname: Pruna
authors.affiliation: Institute of Cellular Biology and Pathology "Nicolae Simionescu", 8 B. P. Hasdeu, district 5, Bucharest Ro-050568, Romania.
authors.forename: Victor V
authors.initials: VV
authors.lastname: Jinga
authors.affiliation: Åbo Akademi University, Process Chemistry Centre, Laboratory of Analytical Chemistry, Biskopsgatan 8, Åbo-Turku FI-20500, Finland.
authors.forename: Rose-Marie
authors.initials: RM
authors.lastname: Latonen
authors.affiliation: Åbo Akademi University, Process Chemistry Centre, Laboratory of Analytical Chemistry, Biskopsgatan 8, Åbo-Turku FI-20500, Finland.
authors.forename: Johan
authors.initials: J
authors.lastname: Bobacka
authors.affiliation: Politehnica University Bucharest, Faculty of Applied Chemistry and Materials Science, Department of General Chemistry, 1-7 Polizu, Bucharest Ro-011061, Romania. Electronic address: i_demetrescu@chim.upb.ro.
authors.forename: Ioana
authors.initials: I
authors.lastname: Demetrescu
mesh_terms: D008841:Actin Cytoskeleton / Q000737:chemistry / Q000378:metabolism; D002448:Cell Adhesion / Q000187:drug effects; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D006801:Humans; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D057139:Nanofibers / Q000737:chemistry* / Q000633:toxicity / Q000648:ultrastructure; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: C009495:titanium dioxide; D014025:Titanium
keywords: Cell growth; Electrospinning; Surface modification; TiO(2) nanofiber