title: Air-stable nickel precatalysts for fast and quantitative cross-coupling of aryl sulfamates with aryl neopentylglycolboronates at room temperature.
abstract: A library containing 10 air-stable Ni(II)X(Aryl)(PCy3)2 σ-complexes as precatalysts (X = Cl, Br, OTs, OMs, aryl = 1-naphthyl, 2-naphthyl; X = Cl, 1-acenaphthenyl, 1-(2-methoxynaphthyl), 9-phenanthrenyl, 9-anthracyl) was synthesized and demonstrated to quantitatively cross-couple 2-methoxyphenyl dimethylsulfamate with methyl 4-(5,5-dimethyl-1,3,2-dioxaborinane-2-yl)benzoate at 23 °C in dry THF in the presence of K3PO4(H2O)3.2 in less than 60 min. Lower or higher amounts of H2O in K3PO4 and as received THF mediate the same transformation in a maximum three times longer reaction time.
authors.affiliation: Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19104-6323, United States.
authors.forename: Ryan L
authors.initials: RL
authors.lastname: Jezorek
authors.forename: Na
authors.initials: N
authors.lastname: Zhang
authors.forename: Pawaret
authors.initials: P
authors.lastname: Leowanawat
authors.forename: Matthew H
authors.initials: MH
authors.lastname: Bunner
authors.forename: Nicholas
authors.initials: N
authors.lastname: Gutsche
authors.forename: Aleksander K R
authors.initials: AK
authors.lastname: Pesti
authors.forename: James T
authors.initials: JT
authors.lastname: Olsen
authors.forename: Virgil
authors.initials: V
authors.lastname: Percec