title: Comparison of osteoconductive properties of three different β-tricalcium phosphate graft materials: a pilot histomorphometric study in a pig model.
abstract: OBJECTIVE
  The aim of this study was to compare the de novo bone formation ability and osteoconductive effects of three different β-tricalcium phosphate (β-TCP) graft materials. The micro-architectural parameters of the newly formed bone tissues were also compared among the different graft materials.
  
  
  METHODS
  Eight male Swiss domestic pigs were used in the study. Five bony defects were made with a trephine bur. Three of the defects were filled with Cerasorb®, Kasios® and Poresorb®. The fourth defect was filled with an autogenous bone graft. The last defect remained empty. All subjects were sacrificed after 8 weeks.
  
  
  RESULTS
  When compared to a negative control group, significant healing was observed in all the groups except the Cerasorb group. The osteoconductivity of the Poresorb group was better than that of the other groups (p < 0.05). The difference in the osteoconductivity of the Kasios and Cerasorb groups was statistically significant (p < 0.05). Comparison of the micro-architectural properties of newly formed bone tissues retrieved from the defects showed that those filled with Poresorb were the best.
  
  
  CONCLUSIONS
  β-TCP materials show different results in terms of the volume and characteristics of new bone formation, although they have a similar chemical structure.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mustafa Kemal University, Tayfur Sokmen Kampusu 31100 Antakya, Hatay, Turkey. Electronic address: dridamlar@gmail.com.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Damlar
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cukurova University, Adana, Turkey.
authors.forename: Özgür
authors.initials: Ö
authors.lastname: Erdoğan
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cukurova University, Adana, Turkey.
authors.forename: Ufuk
authors.initials: U
authors.lastname: Tatli
authors.affiliation: Department of Periodontology, Faculty of Dentistry, Mustafa Kemal University, Hatay, Turkey.
authors.forename: Osman F
authors.initials: OF
authors.lastname: Arpağ
authors.affiliation: Private Practice in Oral and Maxillofacial Surgery, Antalya, Turkey.
authors.forename: Ulaş
authors.initials: U
authors.lastname: Görmez
authors.affiliation: Private Practice in Oral and Maxillofacial Surgery, Adana, Turkey.
authors.forename: Yakup
authors.initials: Y
authors.lastname: Üstün
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D064592:Autografts / Q000637:transplantation; D001847:Bone Diseases / Q000601:surgery; D001853:Bone Marrow / Q000473:pathology; D001857:Bone Matrix / Q000473:pathology; D018786:Bone Substitutes / Q000737:chemistry / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000379:methods; D002130:Calcium Phosphates / Q000737:chemistry / Q000627:therapeutic use*; D005624:Frontal Bone / Q000473:pathology / Q000601:surgery; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D008422:Materials Testing; D023421:Models, Animal; D010012:Osteogenesis / Q000502:physiology*; D010316:Particle Size; D016062:Porosity; D034421:Sus scrofa
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate
keywords: Histomorphometry; Osteoconductivity; β-tricalcium phosphate