title: Tomato juice consumption improves blood antioxidative biomarkers in overweight and obese females.
abstract: OBJECTIVE
  A few studies reported the beneficial effects of tomato juice on oxidative stress status. However, supporting data in obese subjects is scarce. This study aimed to determine the effects of tomato juice consumption on erythrocyte antioxidant enzymes, namely, superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase (CAT), plasma total antioxidant capacity (TAC), and serum malondialdehyde (MDA) in overweight and obese females.
  
  
  METHODS
  A randomized controlled clinical trial was conducted on 64 overweight or obese (BMI = 25 kg/m(2) or higher) female students of Shiraz University of Medical Sciences. Subjects randomly received tomato juice (n = 32, 330 ml/d) or water (n = 28) for 20 days. Daily dietary intake, anthropometric measures and blood antioxidant parameters were determined at the beginning and after 20 days intervention period.
  
  
  RESULTS
  Plasma TAC and erythrocyte antioxidant enzymes increased and serum MDA decreased in the intervention group compared with baseline and with the control group (p < 0.05). In the intervention group, similar results were found in overweight, but not in obese, subjects.
  
  
  CONCLUSIONS
  Our results suggest that tomato juice reduces oxidative stress in overweight (and possibly obese) females and, therefore, may prevent from obesity related diseases and promote health.
authors.affiliation: Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mahsa
authors.initials: M
authors.lastname: Ghavipour
authors.affiliation: Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: gsotodeh@tums.ac.ir.
authors.forename: Gity
authors.initials: G
authors.lastname: Sotoudeh
authors.affiliation: Department of Epidemiology, School of Public Health, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Ghorbani
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000032:analysis; D052160:Benzothiazoles / Q000097:blood; D015415:Biomarkers / Q000097:blood*; D015992:Body Mass Index; D001835:Body Weight; D002374:Catalase / Q000097:blood; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004041:Dietary Fats / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D002149:Energy Intake; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D000067030:Fruit and Vegetable Juices; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D018551:Solanum lycopersicum / Q000737:chemistry*; D008315:Malondialdehyde / Q000097:blood; D015596:Nutrition Assessment; D009765:Obesity / Q000097:blood; D050177:Overweight / Q000097:blood; D018384:Oxidative Stress; D013451:Sulfonic Acids / Q000097:blood; D013482:Superoxide Dismutase / Q000097:blood; D055815:Young Adult
chemical_list: D000975:Antioxidants; D052160:Benzothiazoles; D015415:Biomarkers; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D013451:Sulfonic Acids; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; D008315:Malondialdehyde; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase
keywords: Antioxidative biomarkers; Lycopene; Obesity; Oxidative stress; Tomato juice