title: Polybrominated diphenyl ethers in human placenta associated with  neonatal physiological development at a typical e-waste recycling area  in China.
abstract: Our aim of this study was to characterize the exposure pattern of polybrominated diphenyl ethers(PBDEs) in human placenta and assess their potential effects on neonates. Placenta samples were obtained from a typical e-waste area in Guiyu and a reference area in Haojiang, China. The median ΣPBDE concentration was 32.25 ng/g lipid weight (lw) in placenta samples from Guiyu, and 5.13 ng/g lw from Haojiang. BDE-209 predominated in placenta samples, followed by BDE-28, -47, -99 -153, -183. Residence in Guiyu contributed the most to elevated PDBE levels. Neonatal physiological indices, including bodymass index (BMI), Apgar 1 score and head circumference, were reduced in Guiyu group. No significant difference was found in neonatal weight between the two groups, but neonatal body length in Guiyu was increased. Our data suggest prenatal exposure to PBDEs is high at the e-waste recycling area, and may lead to adverse physiological development in the fetus.
authors.affiliation: Laboratory of Environmental Medicine and Developmental Toxicology, Shantou University Medical College, Shantou 515041, China.
authors.forename: Long
authors.initials: L
authors.lastname: Xu
authors.forename: Xia
authors.initials: X
authors.lastname: Huo
authors.forename: Yuling
authors.initials: Y
authors.lastname: Zhang
authors.forename: Weiqiu
authors.initials: W
authors.lastname: Li
authors.forename: Jianqing
authors.initials: J
authors.lastname: Zhang
authors.forename: Xijin
authors.initials: X
authors.lastname: Xu
mesh_terms: D002681:China; D059029:Electronic Waste; D005260:Female; D055768:Halogenated Diphenyl Ethers / Q000378:metabolism* / Q000633:toxicity; D015386:Hazardous Substances / Q000378:metabolism* / Q000633:toxicity; D006801:Humans; D007231:Infant, Newborn; D018811:Maternal Exposure / Q000706:statistics & numerical data*; D010920:Placenta / Q000378:metabolism*; D011075:Polybrominated Biphenyls; D011247:Pregnancy; D059027:Recycling
chemical_list: D055768:Halogenated Diphenyl Ethers; D015386:Hazardous Substances; D011075:Polybrominated Biphenyls; C533760:tribromodiphenyl ether 28; C010902:decabromobiphenyl ether