title: Effect of male and female body mass index on pregnancy and live birth success after in vitro fertilization.
abstract: OBJECTIVE
  To assess the effects of both male and female body mass index (BMI), individually and combined, on IVF outcomes.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  University fertility center.
  
  
  METHODS
  All couples undergoing first fresh IVF cycles, 2005-2010, for whom male and female weight and height information were available (n = 721 couples).
  
  
  METHODS
  None.
  
  
  METHODS
  Embryologic parameters, clinical pregnancy, and live birth incidence.
  
  
  RESULTS
  The average male BMI among the study population was 27.5 ± 4.8 kg/m(2) (range, 17.3-49.3 kg/m(2)), while the average female BMI (n = 721) was 25.2 ± 5.9 kg/m(2) (range, 16.2-50.7 kg/m(2)). Neither male nor female overweight (25-29.9 kg/m(2)), class I obese (30-34.9 kg/m(2)), or class II/III obese (≥35 kg/m(2)) status was significantly associated with fertilization rate, embryo score, or incidence of pregnancy or live birth compared with normal weight (18.5-24.9 kg/m(2)) status after adjusting for male and female age, partner BMI, and parity. Similar null findings were found between combined couple BMI categories and IVF success.
  
  
  CONCLUSIONS
  Our findings support the notion that weight status does not influence fecundity among couples undergoing infertility treatment. Given the limited and conflicting research on BMI and pregnancy success among IVF couples, further research augmented to include other adiposity measures is needed.
authors.affiliation: Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health & Human Development, Rockville, Maryland. Electronic address: schliepkc2@mail.nih.gov.
authors.forename: Karen C
authors.initials: KC
authors.lastname: Schliep
authors.affiliation: Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health & Human Development, Rockville, Maryland.
authors.forename: Sunni L
authors.initials: SL
authors.lastname: Mumford
authors.affiliation: Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health & Human Development, Rockville, Maryland.
authors.forename: Katherine A
authors.initials: KA
authors.lastname: Ahrens
authors.affiliation: Andrology & In Vitro Fertilization Laboratories, University of Utah School of Medicine, Salt Lake City, Utah; Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah; Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, Utah; Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: James M
authors.initials: JM
authors.lastname: Hotaling
authors.affiliation: Andrology & In Vitro Fertilization Laboratories, University of Utah School of Medicine, Salt Lake City, Utah; Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah; Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, Utah; Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Douglas T
authors.initials: DT
authors.lastname: Carrell
authors.affiliation: Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Megan
authors.initials: M
authors.lastname: Link
authors.affiliation: Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health & Human Development, Rockville, Maryland.
authors.forename: Stefanie N
authors.initials: SN
authors.lastname: Hinkle
authors.affiliation: Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health & Human Development, Rockville, Maryland.
authors.forename: Kerri
authors.initials: K
authors.lastname: Kissell
authors.affiliation: Department of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Christina A
authors.initials: CA
authors.lastname: Porucznik
authors.affiliation: Department of Obstetrics and Gynecology, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Ahmad O
authors.initials: AO
authors.lastname: Hammoud
mesh_terms: D000328:Adult; D015992:Body Mass Index; D015331:Cohort Studies; D005260:Female; D005307:Fertilization in Vitro / Q000639:trends*; D006801:Humans; D050498:Live Birth / Q000453:epidemiology*; D008297:Male; D009765:Obesity / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D050177:Overweight / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D011247:Pregnancy; D011446:Prospective Studies
keywords: Body mass index; in vitro fertilization; live birth; obesity; pregnancy