title: Palladium-catalyzed ortho-sulfonylation of 2-aryloxypyridines and subsequent formation of ortho-sulfonylated phenols.
abstract: A palladium-catalyzed direct sulfonylation of 2-aryloxypyridines on the ortho-position of the benzene ring was developed using 2-pyridyloxyl as the directing group and sulfonyl chlorides as sulfonylation reagents. The protocol was available for both electron-rich and electron-deficient substrates. The ortho-sulfonylated phenol was synthesized expediently from the sulfonylation product by the removal of the pyridyl group.
authors.affiliation: Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Provincial Key Laboratory of Material Cycle Processes and Pollution Control, College of Chemistry and Materials Science, Nanjing Normal University , Nanjing 210097, China.
authors.forename: Yinfeng
authors.initials: Y
authors.lastname: Xu
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
authors.forename: Shun-Li
authors.initials: SL
authors.lastname: Li
authors.forename: Peipei
authors.initials: P
authors.lastname: Sun
mesh_terms: D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D010636:Phenols / Q000138:chemical synthesis* / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry*; D013237:Stereoisomerism; D013441:Sulfinic Acids / Q000737:chemistry*
chemical_list: D010636:Phenols; D011725:Pyridines; D013441:Sulfinic Acids; D010165:Palladium; C044255:sulfonyl chloride