title: [Progressive multifocal leukoencephalopathy in a patient with multiple myeloma].
abstract: Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease in the central nervous system. It is caused by reactivation of John Cunningham-virus and has a grave prognosis. PML occurs most frequently in HIV-patients, but can also be seen in patients with iatrogenic immunodeficiency. Here, we present a patient with multiple myeloma and cardiac amyloidosis who developed PML after receiving treatment with several chemotherapeutics. This case report underlines the importance of bearing PML in mind when immunocompromised patients develop diffuse neurological symptoms.
authors.affiliation: Dagmarsgade 10, 3. th., 2200 København N. ceciliebwi@gmail.com.
authors.forename: Cecilie Balslev
authors.initials: CB
authors.lastname: Willert
authors.forename: Frederik Neess
authors.initials: FN
authors.lastname: Engsig
authors.forename: Helle Wulf
authors.initials: HW
authors.lastname: Eskildsen
authors.forename: Ase Bengård
authors.initials: AB
authors.lastname: Andersen
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D007577:JC Virus / Q000302:isolation & purification; D007968:Leukoencephalopathy, Progressive Multifocal / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009101:Multiple Myeloma / Q000188:drug therapy
chemical_list: D000998:Antiviral Agents; D007166:Immunosuppressive Agents