title: Opening the gate to DNA replication.
authors.affiliation: a DNA Replication Group; Institute of Clinical Science; Imperial College ; London , UK.
authors.forename: Alberto
authors.initials: A
authors.lastname: Riera
authors.forename: Christian
authors.initials: C
authors.lastname: Speck
mesh_terms: D018797:Cell Cycle Proteins / Q000378:metabolism; D004247:DNA / Q000235:genetics / Q000378:metabolism; D004261:DNA Replication / Q000187:drug effects; D004268:DNA-Binding Proteins / Q000378:metabolism; D064110:Minichromosome Maintenance Proteins / Q000378:metabolism; D051738:Origin Recognition Complex / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D020123:Sirolimus / Q000494:pharmacology
chemical_list: D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D051738:Origin Recognition Complex; D029701:Saccharomyces cerevisiae Proteins; C499592:TAH11 protein, S cerevisiae; D004247:DNA; D064110:Minichromosome Maintenance Proteins; D020123:Sirolimus
keywords: DNA entry gate; DNA licensing; DNA replication; MCM2-7; pre-RC; replicative helicase