title: Giant cranial and cerebellar hemangioma treated with propranolol.
abstract: BACKGROUND
  Infantile hemangiomas are the most common benign tumors in children. However, cranial involvement of such lesions is rare. Current treatment options for hemangiomas in various locations that would be endangering or disfiguring include follow-up, surgical removal, or administration of corticosteroids, interferon-α, thalidomide, vincristine, propranolol, and laser therapy.
  
  
  METHODS
  We describe an infant who presented with an extensive cranial hemangioma (proven by a biopsy). The child was treated with propranolol.
  
  
  RESULTS
  Clinical and radiological follow-up for over a year showed significant reduction in tumor size without adverse clinical symptoms.
  
  
  CONCLUSIONS
  Propranolol is a valid treatment for large cranial hemangiomas, avoiding the risks involved in surgeries.
authors.affiliation: Rappaport School of Medicine, Technion, Haifa, Israel.
authors.forename: Haggai
authors.initials: H
authors.lastname: Benvenisti
authors.forename: Liat
authors.initials: L
authors.lastname: Ben-Sira
authors.forename: Shlomi
authors.initials: S
authors.lastname: Constantini
authors.forename: Jonathan
authors.initials: J
authors.lastname: Roth
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D002528:Cerebellar Neoplasms / Q000188:drug therapy*; D005260:Female; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D011433:Propranolol / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol