title: Commentary on "Upper tract imaging surveillance is not effective in diagnosing upper tract recurrence in patients followed fornonmuscle invasive bladder cancer." Sternberg IA, Chen LY, Herr HW, Donat SM, Bochner BH, Dalbagni G, Urology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY.: J Urol 2013; 190(4):1187-91. doi:10.1016/j.juro.2013.05.020. [Epub 2013 May 13].
abstract: OBJECTIVE
  We evaluated the usefulness of routine upper tract imaging in patients followed for nonmuscle invasive bladder cancer.
  
  
  METHODS
  A retrospective review of patients treated for nonmuscle invasive bladder cancer between 2000 and 2006 was conducted. Kaplan-Meier curves were calculated to determine upper tract urothelial carcinoma-free probability for stage Ta and T1 disease. Bladder cancer stage was included as a time dependent covariate. Descriptive statistics were used to report rates of imaging studies used and the efficacy in diagnosing upper tract urothelial carcinoma.
  
  
  RESULTS
  Of 935 patients treated and followed for nonmuscle invasive bladder cancer 51 were diagnosed with upper tract urothelial carcinoma. Median followup was 5.5 years. The 5-year upper tract urothelial carcinoma-free probability among patients with Ta and T1 disease was 98% and 93%, respectively. The 10-year upper tract urothelial carcinoma-free probability among patients with Ta and T1 disease was 94% and 88%, respectively. Only 15 (29%) patients were diagnosed on routine imaging while the others were diagnosed after symptoms developed. Overall 3,074 routine imaging scans were conducted for an overall efficacy of 0.49%.
  
  
  CONCLUSIONS
  Upper tract recurrence is a lifelong risk in patients with bladder cancer, but most cases will be missed on routine upper tract imaging. The majority of upper tract urothelial carcinoma can be diagnosed using a combination of thorough history taking, physical examination, urine cytology and sonography, indicating that routine surveillance imaging may not be the most efficient way to detect upper tract recurrence.
authors.forename: Ashish
authors.initials: A
authors.lastname: Kamat
mesh_terms: D002295:Carcinoma, Transitional Cell / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed; D014516:Ureteral Neoplasms / Q000000981:diagnostic imaging*; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging*