title: [Comparison between magnesium sulfate and dexmedetomidine in controlled hypotension during functional endoscopic sinus surgery].
abstract: OBJECTIVE
  It is crucial to decrease bleeding during functional endoscopic sinus surgery. Our primary goal was to investigate the effects of magnesium sulfate and dexmedetomidine used for controlled hypotension on the visibility of the surgical site.
  
  
  METHODS
  60 patients aged between 18 and 65 years were enrolled. In the magnesium sulfate group (Group M), patients were administered 40mg/kg magnesium sulfate in 100mL saline solution over 10min as the intravenous loading dose 10min before induction, with a subsequent 10-15mg/kg/h infusion during surgery. In the dexmedetomidine group (Group D), patients were administered 1μg/kg dexmedetomidine in 100mL saline solution as the loading dose 10min before surgery and 0.5-1μg/kg/h dexmedetomidine during surgery. Deliberate hypotension was defined as a mean arterial pressure of 60-70mmHg.
  
  
  RESULTS
  Bleeding score was significantly decreased in Group D (p=0.002). Mean arterial pressure values were significantly decreased in Group D compared to that in Group M, except for the initial stage, after induction and 5min after intubation (p<0.05). The number of patients who required nitroglycerine was significantly lower in Group D (p=0.01) and surgeon satisfaction was significantly increased in the same group (p=0.001). Aldrete recovery score ≥9 duration was significantly shorter in Group D (p=0.001). There was no difference between the two groups in terms of recovery room verbal numerical rating scale.
  
  
  CONCLUSIONS
  Dexmedetomidine can provide more effective controlled hypotension and thus contribute to improved visibility of the surgical site.
authors.affiliation: Departamento de Anestesiologia, Medical Faculty, Erciyes University, Kayseri, Turquia. Electronic address: adnanbayram@erciyes.edu.tr.
authors.forename: Adnan
authors.initials: A
authors.lastname: Bayram
authors.affiliation: Departamento de Anestesiologia, Medical Faculty, Erciyes University, Kayseri, Turquia.
authors.forename: Ayşe
authors.initials: A
authors.lastname: Ulgey
authors.affiliation: Departamento de Anestesiologia, Medical Faculty, Erciyes University, Kayseri, Turquia.
authors.forename: Işın
authors.initials: I
authors.lastname: Güneş
authors.affiliation: Departamento de Otorrinolaringologia, Medical Faculty, Erciyes University, Kayseri, Turquia.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Ketenci
authors.affiliation: Departamento de Anestesiologia, Medical Faculty, Erciyes University, Kayseri, Turquia.
authors.forename: Ayşe
authors.initials: A
authors.lastname: Capar
authors.affiliation: Departamento de Anestesiologia, Medical Faculty, Erciyes University, Kayseri, Turquia.
authors.forename: Aliye
authors.initials: A
authors.lastname: Esmaoğlu
authors.affiliation: Departamento de Anestesiologia, Medical Faculty, Erciyes University, Kayseri, Turquia.
authors.forename: Adem
authors.initials: A
authors.lastname: Boyacı
keywords: Cirugia funcional endoscópica dos seios paranasais; Controlled hypotension; Dexmedetomidina; Dexmedetomidine; Functional endoscopic sinus surgery; Hipotensão controlada; Magnesium sulfate; Sulfato de magnésio