title: Pediatric head and neck tumors: an intra-demographic analysis using the SEER* database.
abstract: BACKGROUND
  The aim of this study was to determine the most frequently presenting tumors exclusive to the head and neck within the pediatric population, and to identify racial disparities within the existing incidence rates.
  
  
  METHODS
  The population-based Surveillance, Epidemiology, and End Results (SEER) registry was utilized to identify the frequency and incidence rates of various tumors found exclusively in the head and neck, diagnosed between 1973 and 2008 in pediatric patients. The tumor categories were based on those defined by the US Department of Health and Human Services National Cancer Institute (NCI). Proportional comparisons were applied to evaluate the intra-demographic incidence rate differences.
  
  
  RESULTS
  Among the 11 categories defined, the 5 most prevalent head and neck cancers within the pediatric population were salivary gland tumors (n=319); followed by nasopharyngeal neoplasms (n=311); tumors of the nose, nasal cavity and middle ear (n=208); gum and other mouth tumors (n=134); and glossal tumors (n=61). Proportional comparisons between racial frequency rates indicated that salivary gland tumors were greatest among white pediatric patients (n=246, CI=0.8 to 14.1%, p<.05). Nasopharyngeal cancers were highest among blacks (CI=-26.8 to -12.1%) and other races (CI=-23.6 to -3.4%) relative to the white population.
  
  
  CONCLUSIONS
  Salivary gland tumors were the most commonly seen head and neck tumors overall among pediatric patients between 1973 and 2008. Incidence rate differences between white, black, and other racial background pediatric patients revealed that overall, head and neck tumors are most prevalent among pediatric patients within the white ethnic population, while nasopharyngeal tumors showed a strong prevalence in blacks and other ethnic populations.
authors.affiliation: Departments of Neurologic and Orthopedic Surgery, Mayo Clinic, Rochester, USA.
authors.forename: Alper
authors.initials: A
authors.lastname: Cesmebasi
authors.affiliation: Department of Internal Medicine, Harlem Hospital, New York, USA.
authors.forename: Abigail
authors.initials: A
authors.lastname: Gabriel
authors.affiliation: Department of Anatomical Sciences, St. George's University, St. George's, Grenada.
authors.forename: Daniel
authors.initials: D
authors.lastname: Niku
authors.affiliation: Department of Anatomical Sciences, St. George's University, St. George's, Grenada.
authors.forename: Karolina
authors.initials: K
authors.lastname: Bukala
authors.affiliation: Department of Anatomical Sciences, St. George's University, St. George's, Grenada.
authors.forename: Joseph
authors.initials: J
authors.lastname: Donnelly
authors.affiliation: Department of Anatomical Sciences, St. George's University, St. George's, Grenada.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Fields
authors.affiliation: Department of Pediatric Neurosurgery, Children's Hospital, Birmingham, USA.
authors.forename: R Shane
authors.initials: RS
authors.lastname: Tubbs
authors.affiliation: Department of Anatomical Sciences, St. George's University, St. George, Grenada.
authors.forename: Marios
authors.initials: M
authors.lastname: Loukas
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D019992:Databases as Topic; D003710:Demography; D005006:Ethnicity; D006258:Head and Neck Neoplasms / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007223:Infant; D012044:Regression Analysis; D018426:SEER Program; D055815:Young Adult