title: Chemical and bioanalytical assessments on drinking water treatments by quaternized magnetic microspheres.
abstract: This study aimed to compare the toxicity reduction performance of conventional drinking water treatment (CT) and a treatment (NT) with quaternized magnetic microspheres (NDMP) based on chemical analyses. Fluorescence excitation-emission-matrix combined with parallel factor analysis identified four components in source water of different rivers or lake, and the abundance of each component differed greatly among the different samples. Compared with the CT, the NT evidently reduced the concentrations of dissolved organic carbon, adsorbable organic halogens (AOX), bromide and disinfection by-products. Toxicological evaluation indicated that the NT completely eliminated the cytotoxicity, and greatly reduced the genotoxicity and oxidative stress of all raw water. In contrast, the CT increased the cytotoxicity of Taihu Lake and the Zhongshan River water, genotoxicity of Taihu Lake and the Mangshe River water, as well as the levels of superoxide dismutase and malondialdehyde of the Mangshe River water. Correlation analysis indicated that the AOX of the treated samples was significantly correlated with the genotoxicity and glutathione concentration, but exhibited no correlation with either of them for all the samples. As it can effectively reduce pollutant levels and the toxicities of drinking water, NDMP might be widely used for drinking water treatment in future.
authors.affiliation: State Key Laboratory of Pollution Control and Resource Reuse, Environmental Health Research Center, School of the Environment, Nanjing University, Nanjing 210023, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Shi
authors.affiliation: State Key Laboratory of Pollution Control and Resource Reuse, Environmental Health Research Center, School of the Environment, Nanjing University, Nanjing 210023, China; National Engineering Research Center of Organic Pollution Control and Resource Reuse, Nanjing 210023, China.
authors.forename: Rong
authors.initials: R
authors.lastname: Ma
authors.affiliation: State Key Laboratory of Pollution Control and Resource Reuse, Environmental Health Research Center, School of the Environment, Nanjing University, Nanjing 210023, China; National Engineering Research Center of Organic Pollution Control and Resource Reuse, Nanjing 210023, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhou
authors.affiliation: State Key Laboratory of Pollution Control and Resource Reuse, Environmental Health Research Center, School of the Environment, Nanjing University, Nanjing 210023, China; National Engineering Research Center of Organic Pollution Control and Resource Reuse, Nanjing 210023, China. Electronic address: liaimin@nju.edu.cn.
authors.forename: Aimin
authors.initials: A
authors.lastname: Li
authors.affiliation: State Key Laboratory of Pollution Control and Resource Reuse, Environmental Health Research Center, School of the Environment, Nanjing University, Nanjing 210023, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Wu
authors.affiliation: State Key Laboratory of Pollution Control and Resource Reuse, Environmental Health Research Center, School of the Environment, Nanjing University, Nanjing 210023, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Miao
authors.affiliation: State Key Laboratory of Pollution Control and Resource Reuse, Environmental Health Research Center, School of the Environment, Nanjing University, Nanjing 210023, China.
authors.forename: Xun
authors.initials: X
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Pollution Control and Resource Reuse, Environmental Health Research Center, School of the Environment, Nanjing University, Nanjing 210023, China. Electronic address: zhangxx@nju.edu.cn.
authors.forename: Xuxiang
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000085:Acetates / Q000032:analysis / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects; D004249:DNA Damage; D060766:Drinking Water; D005978:Glutathione / Q000378:metabolism; D056945:Hep G2 Cells; D006801:Humans; D060106:Lakes; D060328:Magnetic Phenomena; D008315:Malondialdehyde / Q000378:metabolism; D008863:Microspheres; D045483:Rivers; D013482:Superoxide Dismutase / Q000378:metabolism; D022882:Trihalomethanes / Q000032:analysis / Q000633:toxicity; D014873:Water Pollutants / Q000032:analysis / Q000633:toxicity; D018508:Water Purification / Q000379:methods*; D014881:Water Supply / Q000032:analysis
chemical_list: D000085:Acetates; D060766:Drinking Water; D022882:Trihalomethanes; D014873:Water Pollutants; D008315:Malondialdehyde; D013482:Superoxide Dismutase; D005978:Glutathione
keywords: Disinfection by-products; Dissolved organic matter; Drinking water; Magnetic ion exchange; Quaternized magnetic microspheres; Toxicity