title: [Neurochemical properties of sensory neurons in the development].
abstract: Sensory neurons represent various groups of neurons differ on their morphological, immunohistochemical and receptor characteristics. The most of large neurons with myelinated Aδ fibers contain neurofilament 200 (NF200), some small afferent neurons can bind the isolectin B4 (IB4). Also, sensory neurons may include different types of tyrosine kinases (trkA, B and C) and neurotransmitters. Neuropeptides are generally located in small and medium-sized neurons. The proportion of neurons which contain trkA decreases and the percentage of NF200-, IB4-, substance P- and CGRP-positive neurons increases during the early development. Development of different types of sensory neurons fulfill under control of neurotrophins.
authors.forename: P M
authors.initials: PM
authors.lastname: Masliukov
authors.forename: V V
authors.initials: VV
authors.lastname: Porseva
authors.forename: M V
authors.initials: MV
authors.lastname: Korzina
authors.forename: A D
authors.initials: AD
authors.lastname: Nozdrachev
mesh_terms: D000818:Animals; D004622:Embryo, Mammalian; D047108:Embryonic Development / Q000502:physiology*; D005727:Ganglia, Spinal / Q000254:growth & development / Q000378:metabolism; D018377:Neurotransmitter Agents / Q000378:metabolism*; D009619:Nociceptors / Q000378:metabolism; D011505:Protein-Tyrosine Kinases / Q000378:metabolism*; D012377:Rodentia / Q000254:growth & development; D011984:Sensory Receptor Cells / Q000276:immunology / Q000378:metabolism / Q000502:physiology*
chemical_list: D018377:Neurotransmitter Agents; D011505:Protein-Tyrosine Kinases