title: The impact of preemptive ropivacaine in inguinal hernioplasty--a randomized controlled trial.
abstract: BACKGROUND
  This study was aimed to assess the outcome of Ilioinguinal, Iliohypogastric block and wound infiltration with 0.75% ropivacaine on pain perception, first analgesic request and hospital stay following inguinal Lichtenstein mesh repair.
  
  
  METHODS
  This was a prospective, randomized, double-blind study with 60 patients undergoing inguinal hernioplasty under general anesthesia. Patients were randomly allocated to one of the two groups by the sealed envelope method. Group 1 (n=30) received nerve blocks and incision infiltration with 0.75% ropivacaine while group 2 (n=30) received isotonic saline. Postoperatively pain intensity, time of demand for the first analgesic and duration of hospital stay were assessed.
  
  
  RESULTS
  Median Visual Analog Scale (VAS) score of group 1 was 4 (high=6, low=3) while for group 2 was 5.50 (high=8, low=4) and the p value was <0.001. Mean time for the demand of the first analgesic was prolonged from 1.19±1.05 h to 5.31±1.14 h with the p value of <0.0005, while the mean time of hospital stay was reduced from 22.5±3.30 h to 14.1±2.99 h with the p value of <0.0005.
  
  
  CONCLUSIONS
  Preemptive analgesia with 0.75% ropivacaine causes significant reduction in pain perception, request for an analgesic and hospital stay. Therefore it is advisable before inguinal hernioplasty.
authors.affiliation: Department of Surgery, Ghurki Trust Teaching Hospital, Jallo Mor, Lahore, Pakistan.
authors.forename: M
authors.initials: M
authors.lastname: Saeed
authors.affiliation: Department of Surgery, Ghurki Trust Teaching Hospital, Jallo Mor, Lahore, Pakistan.
authors.forename: W I
authors.initials: WI
authors.lastname: Andrabi
authors.affiliation: Department of Surgery, Ghurki Trust Teaching Hospital, Jallo Mor, Lahore, Pakistan.
authors.forename: S
authors.initials: S
authors.lastname: Rabbani
authors.affiliation: Department of Surgery, Ghurki Trust Teaching Hospital, Jallo Mor, Lahore, Pakistan.
authors.forename: S
authors.initials: S
authors.lastname: Zahur
authors.affiliation: Department of Surgery, Ghurki Trust Teaching Hospital, Jallo Mor, Lahore, Pakistan.
authors.forename: K
authors.initials: K
authors.lastname: Mahmood
authors.affiliation: Department of Surgery, Ghurki Trust Teaching Hospital, Jallo Mor, Lahore, Pakistan. Electronic address: imranandrabi@gmail.com.
authors.forename: S I
authors.initials: SI
authors.lastname: Andrabi
authors.affiliation: Department of Surgery, Ghurki Trust Teaching Hospital, Jallo Mor, Lahore, Pakistan.
authors.forename: H A
authors.initials: HA
authors.lastname: Butt
authors.affiliation: Department of Surgery, Ghurki Trust Teaching Hospital, Jallo Mor, Lahore, Pakistan.
authors.forename: A M
authors.initials: AM
authors.lastname: Chaudhry
mesh_terms: D000328:Adult; D000368:Aged; D000577:Amides; D000779:Anesthetics, Local; D004311:Double-Blind Method; D005260:Female; D006119:Groin / Q000601:surgery; D006552:Hernia, Inguinal / Q000601:surgery*; D059685:Herniorrhaphy / Q000379:methods*; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009407:Nerve Block / Q000379:methods*; D058748:Pain Perception / Q000187:drug effects; D010149:Postoperative Pain / Q000188:drug therapy / Q000517:prevention & control*; D011446:Prospective Studies; D000077212:Ropivacaine; D013526:Surgical Mesh; D064232:Visual Analog Scale
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine
keywords: Inguinal hernioplasty; Lichtenstein mesh repair; Local anesthesia; Postoperative pain; Preemptive analgesia; Ropivacaine