title: Does vitamin D status correlate with clinical and biochemical features of polycystic ovarysyndrome in high school girls?
abstract: BACKGROUND
  Prevalence of polycystic ovary syndrome (PCOs) is increasing particularly among the female adolescents and young women. It has been hypothesized that disturbance in calcium and vitamin-D metabolism may affect the symptoms of this syndrome. This study was designed to investigate the relationship between vitamin-D and calcium with metabolic parameters and other characteristics of the PCOs.
  
  
  METHODS
  The study included 192 Iranian girls (16-20 years old), of whom 104 had PCOs and 88 were non-PCOs controls. Serum 25(OH) D and calcium level was measured. Anthropometric components, endocrine, metabolic components and insulin resistance were determined in PCOs subjects.
  
  
  RESULTS
  Mean 25 (OH) D was significantly lower in cases (9.7±4.8) than controls (12.3±11.9) but calcium level did not differ between the two groups (9.3±0.3 vs 9.4±0.4). No significant correlations were found between 25(OH) D levels and lipid profile, FBS, fasting insulin endocrine parameters such as testosterone, free testosterone, FSH, LH, and prolactin.
  
  
  CONCLUSIONS
  Although hypovitamionos D was common is PCOs but did not correlate with clinical features or complications of obesity and insulin resistance PCO like severity of syndrome between vitamin-D deficiency and its severity with some features and complications of PCOs including obesity, insulin resistance.
authors.affiliation: Social Determinants of Health Research Center, Babol University of Medical Sciences, Babol, Iran. ; Fatemeh Zahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Ghadimi
authors.affiliation: Fatemeh Zahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.
authors.forename: Sedighe
authors.initials: S
authors.lastname: Esmaeilzadeh
authors.affiliation: Fatemeh Zahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran.
authors.forename: Marmar
authors.initials: M
authors.lastname: Firoozpour
authors.affiliation: Babol University of Medical Sciences, Babol, Iran.
authors.forename: Asal
authors.initials: A
authors.lastname: Ahmadi
keywords: Calcium; Polycystic ovary syndrome; Vitamin-D; Younger girls