title: Bone and metabolic complications of urinary diversions.
abstract: Hyperchloremic metabolic acidosis is a complication of urinary diversion using ileum or colon. Its prevalence ranges from 25% and 46% depending on the procedure used and renal function of the patient. It is a consequence of intestinal fluid and electrolyte exchange between intestinal mucosa and urine. The main mechanism is absorption of ammonium and chloride from urine. Long-term chronic metabolic acidosis in these patients may lead to impaired bone metabolism and osteomalacia. Regular monitoring of pH, chlorine, bicarbonate, and calcium-phosphorus metabolism is therefore essential for early diagnosis and treatment.
authors.affiliation: Servicio de Nefrología, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España. Electronic address: mcanomegias@gmail.com.
authors.forename: Marta
authors.initials: M
authors.lastname: Cano Megías
authors.affiliation: Servicio de Urología, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España.
authors.forename: Eva Golmayo
authors.initials: EG
authors.lastname: Muñoz Delgado
mesh_terms: D000138:Acidosis / Q000209:etiology*; D000471:Alkalosis / Q000209:etiology; D001639:Bicarbonates / Q000097:blood; D001851:Bone Diseases, Metabolic / Q000209:etiology*; D002118:Calcium / Q000097:blood; D002712:Chlorides / Q000097:blood; D003106:Colon / Q000601:surgery; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D007008:Hypokalemia / Q000209:etiology; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000378:metabolism; D007421:Intestine, Small / Q000601:surgery; D010018:Osteomalacia / Q000209:etiology; D010758:Phosphorus / Q000097:blood; D011183:Postoperative Complications / Q000209:etiology*; D013270:Stomach / Q000601:surgery; D014547:Urinary Diversion / Q000009:adverse effects*
chemical_list: D001639:Bicarbonates; D002712:Chlorides; D010758:Phosphorus; D002118:Calcium
keywords: Acidosis metabólica; Conducto ileal; Derivación urinaria; Hipopotasemia; Hypokalemia; Ileal conduit; Metabolic acidosis; Neobladder; Neovejiga; Urinary diversion