title: A novel biosensor based on single-layer MoS2 nanosheets for detection of Ag(+).
abstract: In this work, we use for the first time single layer MoS2 as the fluorescence quencher to design a detection method for Ag(+) with excellent robustness, selectivity and sensitivity. To maintain the ultrathin MoS2, bulk MoS2 materials have been exfoliated by intercalation with lithium followed by reaction with water. As-prepared two-dimensional MoS2 not only has good water-solubility but also obtains high fluorescence quenching efficiency within 5 min. Importantly, the detection limit of this assay for Ag(+) (1 nM) was lower than the maximum limitation guided by the United States Environmental Protection Agency (EPA) and the World Health Organization (WHO). Further, this new Ag(+) probe was demonstrated in monitoring Ag(+) in lake water samples with satisfactory results.
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
authors.forename: Kang
authors.initials: K
authors.lastname: Mao
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
authors.forename: Zitong
authors.initials: Z
authors.lastname: Wu
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
authors.forename: Yinran
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China. Electronic address: zhouxd@whu.edu.cn.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
authors.forename: Aiguo
authors.initials: A
authors.lastname: Shen
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
authors.forename: Jiming
authors.initials: J
authors.lastname: Hu
mesh_terms: D015374:Biosensing Techniques; D002414:Cations, Monovalent; D004277:DNA, Single-Stranded / Q000737:chemistry; D004220:Disulfides / Q000737:chemistry*; D016650:Fluorescein-5-isothiocyanate / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D060106:Lakes / Q000737:chemistry; D057230:Limit of Detection; D008982:Molybdenum / Q000737:chemistry*; D053761:Nanocomposites / Q000737:chemistry*; D009841:Oligonucleotides / Q000737:chemistry; D012834:Silver / Q000032:analysis*; D013050:Spectrometry, Fluorescence; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D002414:Cations, Monovalent; D004277:DNA, Single-Stranded; D004220:Disulfides; D005456:Fluorescent Dyes; D009841:Oligonucleotides; D014874:Water Pollutants, Chemical; D012834:Silver; D008982:Molybdenum; D016650:Fluorescein-5-isothiocyanate; C082964:molybdenum disulfide
keywords: Ag(+); Fluorescence detection; Single layer MoS(2); “C–Ag(+)–C”