title: On-chip cavity-enhanced absorption spectroscopy using a white light-emitting diode and polymer mirrors.
abstract: We have developed a disposable microfluidic chip with integrated cavity mirrors comprised of two pieces of 3M Vikuiti™ enhanced specular reflector II (ESRII) film, for performing cavity-enhanced absorption spectroscopy with a white light-emitting diode (LED). Compared to measurements made with a chip without cavity mirrors, the absorption path length is enhanced by a maximum factor of 28 at 544 nm, and the sensitivity is enhanced by approximately 5 times, enabling micromolar range detection limits to be achieved in an optical path length of only 50 μm.
authors.affiliation: School of Electronics and Computer Science, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK. hm@ecs.soton.ac.uk.
authors.forename: Cathy M
authors.initials: CM
authors.lastname: Rushworth
authors.forename: Gareth
authors.initials: G
authors.lastname: Jones
authors.forename: Martin
authors.initials: M
authors.lastname: Fischlechner
authors.forename: Emma
authors.initials: E
authors.lastname: Walton
authors.forename: Hywel
authors.initials: H
authors.lastname: Morgan
mesh_terms: D004867:Equipment Design; D056656:Lab-On-A-Chip Devices; D008027:Light; D011108:Polymers / Q000737:chemistry*; D013057:Spectrum Analysis / Q000295:instrumentation*
chemical_list: D011108:Polymers