title: Plasmapheresis: Lifesaving treatment in severe cases of HELLP syndrome.
abstract: BACKGROUND
  HELLP syndrome is an important complications in pregnancy which increases maternal and fetal mortality. This disease usually remits with supportive treatment which includes prescription of corticosteroid, magnesium sulfate, stabilization of mother and pregnancy termination. Plasmapheresis is a treatment of choice which improves clinical outcomes in complicated cases.
  
  
  METHODS
  A 22-year-old woman with coagulopathy and respiratory distress and 33-year-old woman with a history of cerebellar medulloblastoma at 32-weeks' gestation developed thrombocytopenia due to HELLP syndrome were treated with plasmapheresis were described.
  
  
  CONCLUSIONS
  Plasmapheresis can significantly improve the outcome of patients with HELLP syndrome who are unresponsive to conservative therapy.
authors.affiliation: Clinical Research Development Center, Qom University of Medical Sciences, Qom, Iran.
authors.forename: Jamshid
authors.initials: J
authors.lastname: Vafaeimanesh
authors.affiliation: Shahid Beheshti Hospital, Qom University of Medical Sciences, Qom, Iran.
authors.forename: Azam
authors.initials: A
authors.lastname: Nazari
authors.affiliation: Clinical Research Development Center, Qom University of Medical Sciences, Qom, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Hosseinzadeh
keywords: HELLP syndrome; Plasmapheresis; Thrombocytopenia