title: The Halophile protein database.
abstract: Halophilic archaea/bacteria adapt to different salt concentration, namely extreme, moderate and low. These type of adaptations may occur as a result of modification of protein structure and other changes in different cell organelles. Thus proteins may play an important role in the adaptation of halophilic archaea/bacteria to saline conditions. The Halophile protein database (HProtDB) is a systematic attempt to document the biochemical and biophysical properties of proteins from halophilic archaea/bacteria which may be involved in adaptation of these organisms to saline conditions. In this database, various physicochemical properties such as molecular weight, theoretical pI, amino acid composition, atomic composition, estimated half-life, instability index, aliphatic index and grand average of hydropathicity (Gravy) have been listed. These physicochemical properties play an important role in identifying the protein structure, bonding pattern and function of the specific proteins. This database is comprehensive, manually curated, non-redundant catalogue of proteins. The database currently contains 59 897 proteins properties extracted from 21 different strains of halophilic archaea/bacteria. The database can be accessed through link. Database URL: http://webapp.cabgrid.res.in/protein/
authors.affiliation: Center for Agricultural Bioinformatics, Indian Agricultural Statistics Research Institute, Pusa Campus, New Delhi 110012, India.
authors.forename: Naveen
authors.initials: N
authors.lastname: Sharma
authors.affiliation: Center for Agricultural Bioinformatics, Indian Agricultural Statistics Research Institute, Pusa Campus, New Delhi 110012, India samir@iasri.res.in.
authors.forename: Mohammad Samir
authors.initials: MS
authors.lastname: Farooqi
authors.affiliation: Center for Agricultural Bioinformatics, Indian Agricultural Statistics Research Institute, Pusa Campus, New Delhi 110012, India.
authors.forename: Krishna Kumar
authors.initials: KK
authors.lastname: Chaturvedi
authors.affiliation: Center for Agricultural Bioinformatics, Indian Agricultural Statistics Research Institute, Pusa Campus, New Delhi 110012, India.
authors.forename: Shashi Bhushan
authors.initials: SB
authors.lastname: Lal
authors.affiliation: Center for Agricultural Bioinformatics, Indian Agricultural Statistics Research Institute, Pusa Campus, New Delhi 110012, India.
authors.forename: Monendra
authors.initials: M
authors.lastname: Grover
authors.affiliation: Center for Agricultural Bioinformatics, Indian Agricultural Statistics Research Institute, Pusa Campus, New Delhi 110012, India.
authors.forename: Anil
authors.initials: A
authors.lastname: Rai
authors.affiliation: Center for Agricultural Bioinformatics, Indian Agricultural Statistics Research Institute, Pusa Campus, New Delhi 110012, India.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Pandey
mesh_terms: D001105:Archaea / Q000378:metabolism*; D019843:Archaeal Proteins / Q000378:metabolism*; D001419:Bacteria / Q000378:metabolism*; D001426:Bacterial Proteins / Q000378:metabolism*; D030562:Databases, Protein
chemical_list: D019843:Archaeal Proteins; D001426:Bacterial Proteins