title: Relation between symptoms and pathophysiology in inflammatory neuropathies: Controversies and hypotheses.
abstract: This review attempts to explain the symptoms experienced by patients with inflammatory neuropathies by pathophysiological events. The emphasis is not on the primary events that may cause a particular illness but on downstream events taking place in peripheral nerves or muscles. Symptoms that will be discussed include sensory predominance, motor predominance, activity-induced weakness, heat paresis, and cold paresis. Each symptom is associated with, but not limited to, particular neuropathies.
authors.affiliation: Brain Center Rudolf Magnus, Section Neuromuscular Disorders, Department of Neurology F02.230, University Medical Center Utrecht, Heidelberglaan 100, 3584CX Utrecht, Netherlands. Electronic address: H.Franssen@umcutrecht.nl.
authors.forename: Hessel
authors.initials: H
authors.lastname: Franssen
mesh_terms: D001369:Axons / Q000502:physiology; D003080:Cold Temperature; D020275:Guillain-Barre Syndrome / Q000503:physiopathology; D006358:Hot Temperature; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D018908:Muscle Weakness / Q000503:physiopathology; D018482:Muscle, Skeletal / Q000503:physiopathology; D009186:Myelin Sheath / Q000502:physiology; D010291:Paresis / Q000503:physiopathology; D011115:Polyneuropathies / Q000503:physiopathology*
keywords: axon; demyelination; ion-channels; neuropathy; symptoms