title: Surface characteristics of and in vitro behavior of osteoblast-like cells on titanium with nanotopography prepared by high-energy shot peening.
abstract: METHODS
  Commercial pure titanium with nanotopography was prepared via a high-energy shot-peening (HESP) technique. The surface characteristics were evaluated, and the preliminary cell responses to the nanotopographical surface were investigated.
  
  
  RESULTS
  The nanotopographical surface layer on titanium was successfully processed by HESP. The average nanoscale grains were approximately 60 nm in diameter and they were nonhomogeneously distributed on the surface. MG-63 cells with an osteogenic phenotype were well adhered and well spread on the nanostructured surface. Compared to the original polished control, the nanotopographical surface highly improved the adhesion, viability, and differentiation of MG-63 cells.
  
  
  CONCLUSIONS
  Titanium with nanotopography achieved by HESP has good cytocompatibility and shows promise for dental implant applications.
authors.affiliation: School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China ; State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, People's Republic of China.
authors.forename: Zhennan
authors.initials: Z
authors.lastname: Deng
authors.affiliation: School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
authors.forename: Baodi
authors.initials: B
authors.lastname: Yin
authors.affiliation: School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
authors.forename: Weihong
authors.initials: W
authors.lastname: Li
authors.affiliation: School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
authors.forename: Jinsong
authors.initials: J
authors.lastname: Liu
authors.affiliation: School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
authors.forename: Jingyuan
authors.initials: J
authors.lastname: Yang
authors.affiliation: School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
authors.forename: Tieli
authors.initials: T
authors.lastname: Zheng
authors.affiliation: School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
authors.forename: Dafeng
authors.initials: D
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, People's Republic of China.
authors.forename: Haiyang
authors.initials: H
authors.lastname: Yu
authors.affiliation: National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, Sichuan, People's Republic of China.
authors.forename: Xiaoguang
authors.initials: X
authors.lastname: Liu
authors.affiliation: School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Ma
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry / Q000633:toxicity; D045744:Cell Line, Tumor; D002468:Cell Physiological Phenomena / Q000187:drug effects; D006801:Humans; D049329:Nanostructures / Q000737:chemistry* / Q000633:toxicity; D036103:Nanotechnology; D010006:Osteoblasts / Q000187:drug effects*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry* / Q000633:toxicity
chemical_list: D001672:Biocompatible Materials; D014025:Titanium
keywords: cytocompatibility; high-energy shot peening; nanotopography; titanium