title: Transcription regulation mechanisms of bacteriophages: recent advances and future prospects.
abstract: Phage diversity significantly contributes to ecology and evolution of new bacterial species through horizontal gene transfer. Therefore, it is essential to understand the mechanisms underlying phage-host interactions. After initial infection, the phage utilizes the transcriptional machinery of the host to direct the expression of its own genes. This review presents a view on the transcriptional regulation mechanisms of bacteriophages, and its contribution to phage diversity and classification. Through this review, we aim to broaden the understanding of phage-host interactions while providing a reference source for researchers studying the regulation of phage transcription.
authors.affiliation: a Key Laboratory of Industrial Biotechnology; Ministry of Education; School of Biotechnology; Jiangnan University; Wuxi, China.
authors.forename: Haiquan
authors.initials: H
authors.lastname: Yang
authors.forename: Yingfang
authors.initials: Y
authors.lastname: Ma
authors.forename: Yitian
authors.initials: Y
authors.lastname: Wang
authors.forename: Haixia
authors.initials: H
authors.lastname: Yang
authors.forename: Wei
authors.initials: W
authors.lastname: Shen
authors.forename: Xianzhong
authors.initials: X
authors.lastname: Chen
mesh_terms: D001435:Bacteriophages / Q000235:genetics*; D012321:DNA-Directed RNA Polymerases / Q000235:genetics; D015967:Gene Expression Regulation, Viral; D011401:Promoter Regions, Genetic / Q000235:genetics
chemical_list: D012321:DNA-Directed RNA Polymerases
keywords: RNA polymerase; bacteriophages; promoter; regulation mechanism; transcription