title: Bromodomain inhibition by JQ1 suppresses lipopolysaccharide-stimulated interleukin-6 secretion in multiple myeloma cells.
authors.affiliation: Brighton and Sussex Medical School, Medical Research Building, University of Sussex, Falmer, Brighton BN1 9PS, UK.
authors.forename: Rohit R
authors.initials: RR
authors.lastname: Ghurye
authors.affiliation: Brighton and Sussex Medical School, Medical Research Building, University of Sussex, Falmer, Brighton BN1 9PS, UK.
authors.forename: Helen J S
authors.initials: HJ
authors.lastname: Stewart
authors.affiliation: Brighton and Sussex Medical School, Medical Research Building, University of Sussex, Falmer, Brighton BN1 9PS, UK. Electronic address: t.chevassut@bsms.ac.uk.
authors.forename: Timothy J
authors.initials: TJ
authors.lastname: Chevassut
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000911:Antibodies, Monoclonal / Q000737:chemistry; D001381:Azepines / Q000737:chemistry*; D002470:Cell Survival; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D015850:Interleukin-6 / Q000378:metabolism*; D008070:Lipopolysaccharides / Q000737:chemistry*; D008297:Male; D009101:Multiple Myeloma / Q000378:metabolism*; D017434:Protein Structure, Tertiary; D060888:Real-Time Polymerase Chain Reaction; D014230:Triazoles / Q000737:chemistry*
chemical_list: C561695:(+)-JQ1 compound; D000911:Antibodies, Monoclonal; D001381:Azepines; C508600:IL6 protein, human; D015850:Interleukin-6; D008070:Lipopolysaccharides; D014230:Triazoles