title: Renal transplantation in a patient with chronic granulomatous disease: case report.
abstract: Chronic granulomatous disease (CGD) is a genetic disease caused by structural mutations in the enzyme NADPH oxidase that results in severe immunodeficiency. End-stage renal disease occurs in this patient population and is attributed to various factors, including infections, amyloidosis, and nephrotoxic anti-infective agents. In this report, we present our experience in transplantation for a patient with CGD complicated by isolated hepatic tuberculosis abscess. The course of the case demonstrates the absolute requirements for a multidisciplinary and compulsive approach before, during, and after transplantation. This case report also highlights the unexpectedly benign effects of immunosuppressive therapy in this patient population.
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, Istanbul University, Istanbul, Turkey. Electronic address: drbaharbudan@gmail.com.
authors.forename: B
authors.initials: B
authors.lastname: Caliskan
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Istanbul University, Istanbul, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Yazici
authors.affiliation: Department of Pathology, Istanbul University, Istanbul, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Gulluoglu
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Istanbul University, Istanbul, Turkey.
authors.forename: Y
authors.initials: Y
authors.lastname: Caliskan
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Istanbul University, Istanbul, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Turkmen
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Istanbul University, Istanbul, Turkey.
authors.forename: M S
authors.initials: MS
authors.lastname: Sever
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D016030:Kidney Transplantation; D008100:Liver Abscess / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D008297:Male
chemical_list: D000890:Anti-Infective Agents; D007166:Immunosuppressive Agents