title: Using genetically isolated populations to understand the genomic basis of disease.
abstract: Rare variation has a key role in the genetic etiology of complex traits. Genetically isolated populations have been established as a powerful resource for novel locus discovery and they combine advantageous characteristics that can be leveraged to expedite discovery. Genome-wide genotyping approaches coupled with sequencing efforts have transformed the landscape of disease genomics and highlight the potentially significant contribution of studies in founder populations.
authors.affiliation: Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA UK.
authors.forename: Eleftheria
authors.initials: E
authors.lastname: Zeggini