title: Multiple heriditary exostoses in a family for three generation of Indian origin with review of literature.
abstract: Multiple hereditary exostoses (MHE) are an autosomal dominant disorder, consisting of multiple cartilage capped bone tumour arising from the metaphysis of long tubular bones. Mutations are seen in Exostosin-1 and Exostosin-2 genes. We present a family of MHE for three generations. The index case was a 10-year-old male presented with multiple exostoses in hand, forearm, leg, right knee and chest. Family history revealed similar complaints in younger brother, father, paternal uncle, paternal aunt & her daughter and grandfather.
authors.affiliation: Professor, Department of Pathology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka, India .
authors.forename: Kalyani
authors.initials: K
authors.lastname: R
authors.affiliation: Professor, Department of Pathology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka, India .
authors.forename: Prabhakar
authors.initials: P
authors.lastname: K
authors.affiliation: Resident, Deparment of Medicine, Department of Pathology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka, India .
authors.forename: Gopinath
authors.initials: G
authors.lastname: B
authors.affiliation: Professor of Orthopaedics, Department of Orthopaedics, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka, India .
authors.forename: Sheik
authors.initials: S
authors.lastname: Naseer B
authors.affiliation: Scientific Adviser, Genome Lab, Genome Lab, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research , Kolar, Karnataka, India .
authors.forename: Krishnamurthy
authors.initials: K
authors.lastname: Ds
keywords: Exostoses; India; Multiple hereditary exostoses