title: A five year retrospective study of short term respiratory support outcomes for infants who received tracheostomy before one year of age.
abstract: OBJECTIVE
  This study aims to describe respiratory support requirements at the time of hospital discharge for infants who undergo tracheostomy, and to determine whether certain indications for tracheostomy are significantly associated with ventilator or oxygen dependence at the time of discharge.
  
  
  METHODS
  Retrospective chart review identified 150 patients who underwent tracheostomy before 1 year of age at a single center from 2007 to 2012 and were discharged alive. Patients were divided into groups based on primary indication for tracheostomy: chronic lung disease (CLD); cardiac; airway anomalies (e.g., tracheomalacia, subglottic stenosis); anatomic anomalies of head, neck and chest; neuro/muscular; mixed group (>1 primary indication). Chi-squared tests were used to compare respiratory support requirements at time of discharge, as well as need for supplemental oxygen.
  
  
  RESULTS
  Of the 150 patients included in the study, three were discharged on room air alone. Of those 147 who did require some form of support at discharge, significant differences were found between groups when comparing CPAP to ventilator support. For example, of the patients with CLD, 82% were discharged on ventilator support whereas of those with a primary airway indication nearly 54% were discharged on CPAP. Significant differences were also found among groups when comparing patients discharged on room air vs. supplemental oxygen. Patients with CLD were more likely to be discharged on supplemental oxygen (p=0.001) whereas of the patients with anatomic indication 77% required no supplemental oxygen at the time of discharge.
  
  
  CONCLUSIONS
  Respiratory support needs at the time of discharge for neonates who underwent tracheostomy varied significantly depending on the initial indication for tracheostomy. Information about respiratory requirements of infants who undergo tracheostomy can help clinicians counsel families and anticipate post-discharge needs.
authors.affiliation: Otorhinolaryngology, University of Pennsylvania Health System, Philadelphia, PA, United States. Electronic address: elizabeth.cottrill@uphs.upenn.edu.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Cottrill
authors.affiliation: Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
authors.forename: Janet
authors.initials: J
authors.lastname: Lioy
authors.affiliation: Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
authors.forename: Summer
authors.initials: S
authors.lastname: Elshenawy
authors.affiliation: Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
authors.forename: Jaclyn
authors.initials: J
authors.lastname: Rosenzweig
authors.affiliation: Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
authors.forename: Edward
authors.initials: E
authors.lastname: Hopkins
authors.affiliation: Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
authors.forename: John
authors.initials: J
authors.lastname: Chuo
authors.affiliation: Otorhinolaryngology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
authors.forename: Steven
authors.initials: S
authors.lastname: Sobol
authors.affiliation: Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA, United States.
authors.forename: Sara
authors.initials: S
authors.lastname: DeMauro
mesh_terms: D045422:Continuous Positive Airway Pressure / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007829:Laryngostenosis / Q000628:therapy; D008171:Lung Diseases / Q000628:therapy; D008297:Male; D010102:Oxygen Inhalation Therapy / Q000706:statistics & numerical data*; D010351:Patient Discharge; D012121:Respiration, Artificial / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D055090:Tracheomalacia / Q000628:therapy; D014139:Tracheostomy
keywords: Airway; Neonate; Outcomes; Tracheostomy