title: A highly selective and sensitive fluorescent probe for quantitative detection of Hg(2+) based on aggregation-induced emission features.
abstract: A π-conjugated cyanostilbene derivative of (Z)-2-(4-nitrophenyl)-3-(4-(vinyloxy)phenyl)acrylonitrile (CN-vinyl) had been designed, synthesized and confirmed by the standard spectroscopic analyses. CN-vinyl possesses an unusual high emissive aggregation-induced emission (AIE) feature in a tetrahydrofuran/water mixture (2:8, v/v). The fluorescence intensity of CN-vinyl can be quenched linearly with the addition of Hg(2+) in a range of 0-50 μM with a correlation coefficient of R(2)=0.9957. The detection limit of Hg(2+) is 37 nM. The mechanism for Hg(2+)-mediated optical properties of CN-vinyl is due to the selective cleavage of vinyl group by Hg(2+). Accuracy of the proposed methodology was evaluated by means of the recovery study in real samples and the analyzing certified reference material of the standard solution of Hg(2+). By this novel strategy, CN-vinyl can be used for quantitative detection of Hg(2+) as well as the presence of other physiological relevant metal ions.
authors.affiliation: Department of Chemistry and Chemical Engineering, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China.
authors.forename: Aizhi
authors.initials: A
authors.lastname: Wang
authors.affiliation: Department of Chemistry and Chemical Engineering, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China. Electronic address: yxyang@ustb.edu.cn.
authors.forename: Yunxu
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Chemistry and Chemical Engineering, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China.
authors.forename: Feifei
authors.initials: F
authors.lastname: Yu
authors.affiliation: Department of Chemistry and Chemical Engineering, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China.
authors.forename: Lingwei
authors.initials: L
authors.lastname: Xue
authors.affiliation: Department of Chemistry and Chemical Engineering, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China.
authors.forename: Biwei
authors.initials: B
authors.lastname: Hu
authors.affiliation: Department of Chemistry and Chemical Engineering, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China.
authors.forename: Weiping
authors.initials: W
authors.lastname: Fan
authors.affiliation: Department of Chemistry and Chemical Engineering, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China.
authors.forename: Yajun
authors.initials: Y
authors.lastname: Dong
mesh_terms: D000181:Acrylonitrile / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D002413:Cations, Divalent; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D005618:Fresh Water / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008628:Mercury / Q000032:analysis*; D012680:Sensitivity and Specificity; D013050:Spectrometry, Fluorescence / Q000379:methods; D014753:Vinyl Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: C000600057:2-(4-nitrophenyl)-3-(4-(vinyloxy)phenyl)acrylonitrile; D002413:Cations, Divalent; D005456:Fluorescent Dyes; D014753:Vinyl Compounds; D014874:Water Pollutants, Chemical; D008628:Mercury; D000181:Acrylonitrile
keywords: Aggregation-induced emission; Fluorescent probe; Mercury ion; Quantitative detection