title: Primitive neuroectodermal tumor (PNET) of the lung in an adult woman.
abstract: Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular genetic analysis of chromosome rearrangements in the EWSR1 gene region. Clinical follow-up, post-mortem findings, and differential diagnosis are also discussed.
authors.affiliation: Department of Clinical and Molecular Pathology and Institute of Molecular and Translational Medicine (IMTM), Faculty of Medicine and Dentistry, Palacky University, Hněvotínská 3, 775 15 Olomouc, Czech Republic. marjammg@gmail.com.
authors.forename: Mariam
authors.initials: M
authors.lastname: Gachechiladze
authors.forename: Josef
authors.initials: J
authors.lastname: Skarda
authors.forename: Maha
authors.initials: M
authors.lastname: Ibrahim
authors.forename: Tomáš
authors.initials: T
authors.lastname: Tichý
authors.forename: Patrik
authors.initials: P
authors.lastname: Flodr
authors.forename: Pavla
authors.initials: P
authors.lastname: Latálová
authors.forename: Jiří
authors.initials: J
authors.lastname: Ehrmann
authors.forename: Radek
authors.initials: R
authors.lastname: Trojanec
authors.forename: Zdenek
authors.initials: Z
authors.lastname: Kolář
mesh_terms: D000328:Adult; D000740:Anemia / Q000139:chemically induced / Q000473:pathology; D000970:Antineoplastic Agents / Q000009:adverse effects; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology*; D018242:Neuroectodermal Tumors, Primitive / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000970:Antineoplastic Agents