title: Relationship of treatment satisfaction to health-related quality of life: findings from a cross-sectional survey among hypertensive patients in Palestine.
abstract: BACKGROUND
  Evaluation of the association between treatment satisfaction and health-related quality of life (HRQoL) may enable health-care providers to understand the issues that influence quality of life and to recognize the aspects of hypertension treatment that need improvement to enhance the long-term treatment outcomes.
  
  
  OBJECTIVE
  The aim of this study was to determine the relationship between HRQoL and treatment satisfaction in a sample of Palestinian hypertensive patients.
  
  
  METHODS
  A cross-sectional study was conducted, adopting the Treatment Satisfaction Questionnaire for Medication (TSQM 1.4) for the assessment of treatment satisfaction and using the European Quality of Life scale (EQ-5D-5L) for the assessment of HRQoL. Descriptive and comparative statistics were used to describe socio-demographic and disease-related characteristics of the patients. All analyses were performed using SPSS v 15.0.
  
  
  RESULTS
  Four hundred and ten hypertensive patients were enrolled in the study. This study findings indicate a positive correlation between all satisfaction domains and HRQoL. Significant differences were observed between this study variables (P < 0.001). After adjustment for covariates using multiple linear regression, an increase of one point in the global satisfaction scale was associated with a 0.16 increase in EQ-5D index scores (r = 0.16; P < 0.001).
  
  
  CONCLUSIONS
  Patients with reportedly higher satisfaction scores have reported relatively higher EQ-5D-5L index values. These study findings could be helpful in clinical practice, mainly in the early treatment of hypertensive patients, at a point where improving treatment satisfaction and HRQoL is still possible.
authors.affiliation: Department of Clinical and Community, Pharmacy College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
authors.forename: Samah W
authors.initials: SW
authors.lastname: Al-Jabi
authors.affiliation: Department of Clinical and Community, Pharmacy College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.|Poison Control and Drug Information Center (PCDIC), College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.|WHO Collaborating Centre for Drug Information, National Poison Centre, Universiti Sains Malaysia (USM), Penang, Malaysia.
authors.forename: Sa'ed H
authors.initials: SH
authors.lastname: Zyoud
authors.affiliation: Department of Pharmacology and Toxicology, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
authors.forename: Waleed M
authors.initials: WM
authors.lastname: Sweileh
authors.affiliation: PharmD Program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
authors.forename: Aysha H
authors.initials: AH
authors.lastname: Wildali
authors.affiliation: PharmD Program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
authors.forename: Hanan M
authors.initials: HM
authors.lastname: Saleem
authors.affiliation: PharmD Program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
authors.forename: Hayat A
authors.initials: HA
authors.lastname: Aysa
authors.affiliation: PharmD Program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Badwan
authors.affiliation: WHO Collaborating Centre for Drug Information, National Poison Centre, Universiti Sains Malaysia (USM), Penang, Malaysia.
authors.forename: Rahmat
authors.initials: R
authors.lastname: Awang
mesh_terms: D000328:Adult; D000368:Aged; D018912:Arabs / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011594:Psychometrics / Q000379:methods; D011788:Quality of Life; D011795:Surveys and Questionnaires
keywords: Treatment Satisfaction Questionnaire for Medication; health-related quality of life; hypertension; quality of life; treatment satisfaction