title: Affine registration of [123I]FP-CIT SPECT brain images.
abstract: In this work, we perform a comparison between the spatial normalization of [123I]FP-CIT SPECT brain images when a FP-CIT SPECT and a MRI template are used. A 12-parameters affine registration model is calculated by the optimization of a sum of squares cost function. When the images are registered to a FP-CIT template, the intersubject variation is found to be lower than when the MRI template is used, specially in the striatum, which is the most relevant part of the brain in FP-CIT SPECT brain images.
authors.affiliation: Dpt. Signal Theory, Networking and Communications, University of Granada, Spain.
authors.forename: Diego
authors.initials: D
authors.lastname: Salas-Gonzalez
authors.affiliation: Dpt. Signal Theory, Networking and Communications, University of Granada, Spain.
authors.forename: Juan M
authors.initials: JM
authors.lastname: Górriz
authors.affiliation: Dpt. Signal Theory, Networking and Communications, University of Granada, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Ramírez
authors.affiliation: Dpt. Signal Theory, Networking and Communications, University of Granada, Spain.
authors.forename: Ignacio
authors.initials: I
authors.lastname: A Illán
authors.affiliation: Dpt. Signal Theory, Networking and Communications, University of Granada, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Padilla
authors.affiliation: Dpt. Signal Theory, Networking and Communications, University of Granada, Spain.
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Martínez-Murcia
authors.affiliation: Institut für Biophysik und physikalische Biochemie, University of Regensburg, Germany.
authors.forename: Elmar W
authors.initials: EW
authors.lastname: Lang
mesh_terms: D003342:Corpus Striatum / Q000000981:diagnostic imaging*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D064847:Multimodal Imaging / Q000379:methods; D010300:Parkinson Disease / Q000000981:diagnostic imaging*; D010363:Pattern Recognition, Automated / Q000379:methods; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014326:Tropanes
chemical_list: D019275:Radiopharmaceuticals; D014326:Tropanes; C087552:2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane