title: Sertoli-leydig cell tumour of ovary with menorrhagia: a rare case report.
abstract: Sertoli-Leydig cell tumours (SLCTs) are rare sex cord stromal neoplasms of ovary accounting for less than 0.5% of all ovarian tumours. These are found in women of all age groups (2-75 y), but are most common in reproductive age group with an average age of 25 y. Mostly these are unilateral, confined to ovaries and usually stage I at the time of clinical diagnosis. The common presenting complaints in these patients are due to either mass occupying lesion (mostly pelviabdominal mass and/or pain) or hormonal production (mostly androgen and more rarely oestrogen). Androgenic manifestations, seen in 80% of patients with SLCT, are virilism, hirsutism, receding hairline, breast atrophy, clitoromegaly, acne, hoarseness of voice, etc. Estrogenic manifestations are precocious puberty, abnormal uterine bleeding, abnormal vaginal bleeding, menstrual irregularities, generalised oedema, weight gain, breast hypertrophy, endometrial hyperplasia, endometrial polyps and endometrial carcinoma. Histologically these are classified (WHO) as well-differentiated, intermediately differentiated, poorly differentiated, with heterologous components and retiform type. Prognosis depends upon degree of tumour differentiation (grading) and tumour extent (staging). We herein report an unusual case of SLCT of ovary with oestrogenic manifestation of menorrhagia.
authors.affiliation: Assistant Professor, Department of Pathology, Government Medical College and Hospital Latur, India .
authors.forename: Umesh Sidheshwar
authors.initials: US
authors.lastname: Kanade
authors.affiliation: Associate Professor, Department of Pathology, Government Medical College and Hospital Latur, India .
authors.forename: Sunita Sanjay
authors.initials: SS
authors.lastname: Dantkale
authors.affiliation: Assistant Professor, Department of Pathology, Government Medical College and Hospital Latur, India .
authors.forename: Rahul Ravindra
authors.initials: RR
authors.lastname: Narkhede
authors.affiliation: Junior Resident, Department of Pathology, Government Medical College and Hospital Latur, India .
authors.forename: Rupali Ramrao
authors.initials: RR
authors.lastname: Kurawar
authors.affiliation: Assistant Professor, Department of Pathology, Government Medical College and Hospital Latur, India .
authors.forename: Shubhada Yadavrao
authors.initials: SY
authors.lastname: Bansode
keywords: Menorrhagia; Sertoli-leydig cell tumour; Sex cord stromal tumour