title: Emergent cardiac surgery with cardiopulmonary bypass in early pregnancy: report of four cases.
abstract: BACKGROUND
  Due to current medical improvements, more women with cardiac disease are being operated during pregnancy. Fetal loss has been found to be significant between 9-30% of them and the surgery is supposed to be done maximal in the first trimester.
  
  
  OBJECTIVE
  The aim of this study was to report our experience with urgent cardiopulmonary bypass carried out in early pregnancy and to analyze factors that may influence fetal and maternal morbidity and mortality after surgery.
  
  
  METHODS
  We have retrospectively reviewed the case notes of the patients who underwent cardiac surgery during early pregnancy in our institution from January 1997 to October 2011.
  
  
  RESULTS
  During that period cardiac surgery was done in 305 patients in childbearing age (between 15-50 years) from which 4 were pregnant and in the first half of their pregnancy. All of them had previous surgery due to rhumatismal heart disease .The surgery was emergent in 3 cases and urgent in 1 case. They were operated under normothermic conditions, high flow and hemodynamic stability throughout the procedure. There was no fetal loss but one patient sustained a cardiac arrest secondary to asthma complicated by post-anoxic brain injury.
  
  
  CONCLUSIONS
  Normothermia and hemodynamic stability are the most important factors which help to reduce fetal loss during open heart surgery in pregnancy. The fetus has an auto-regulation which comes into play when the mother is experiencing shock.
authors.affiliation: Service of Thoracic and Cardiovascular Surgery, Department of Cardiovascular Diseases, Brussels's St Luc University Hospital Center, Brussels, Belgium.
authors.forename: Bernadette
authors.initials: B
authors.lastname: Ngo Nonga
authors.affiliation: Service of Cardiology, Department of Cardiovascular Diseases, Brussels's St Luc University Hospital Center, Brussels, Belgium.
authors.forename: Agnès
authors.initials: A
authors.lastname: Pasquet
authors.affiliation: Service of Thoracic and Cardiovascular Surgery, Department of Cardiovascular Diseases, Brussels's St Luc University Hospital Center, Brussels, Belgium.
authors.forename: Laurent
authors.initials: L
authors.lastname: De Kherkove
authors.affiliation: Service of Thoracic and Cardiovascular Surgery, Department of Cardiovascular Diseases, Brussels's St Luc University Hospital Center, Brussels, Belgium.
authors.forename: David
authors.initials: D
authors.lastname: Glineur
authors.affiliation: Department of Obstetrics and Gynecology, Brussels's St Luc University Hospital Center, Brussels, Belgium.
authors.forename: Frederic
authors.initials: F
authors.lastname: Debieve
authors.affiliation: Department of Obstetrics and Gynecology, Brussels's St Luc University Hospital Center, Brussels, Belgium.
authors.forename: Corinne
authors.initials: C
authors.lastname: Hubinont
authors.affiliation: Service of Thoracic and Cardiovascular Surgery, Department of Cardiovascular Diseases, Brussels's St Luc University Hospital Center, Brussels, Belgium.
authors.forename: Gebrine
authors.initials: G
authors.lastname: El Khoury
authors.affiliation: Service of Thoracic and Cardiovascular Surgery, Department of Cardiovascular Diseases, Brussels's St Luc University Hospital Center, Brussels, Belgium.
authors.forename: Philippe
authors.initials: P
authors.lastname: Noirhomme
keywords: Cardiac Surgery; Cardiopulmonary Bypass; Early Pregnancy; Fetal Loss