title: Body mass index and waist circumference are independent risk factors for low vital capacity among Japanese participants of a health checkup: a single-institution cross-sectional study.
abstract: OBJECTIVE
  This study aimed to examine the associations between obesity and percentage vital capacity (%VC), as well as lifestyle-related disorders, among Japanese participants of a voluntary health checkup.
  
  
  METHODS
  Subjects were 7,892 individuals who participated in a medical health checkup from January to December 2007. Multivariate logistic regression analysis was performed to assess associations between low %VC (<80) and body mass index (BMI) and waist circumference (WC), as well as lifestyle-related disorders.
  
  
  RESULTS
  Medical histories of hypertension and dyslipidemia were more frequent in the low %VC group than in the normal %VC group in both sexes. In men, BMI was significantly associated with low %VC (25.0 ≤ C2 < 27.5, odds ratio (OR) = 2.10; 27.5 ≤ C3 < 30.0, OR = 2.23; C4 ≥ 30.0, OR = 3.46) relative to the first category (C1 < 25.0). A significant association was also observed between WC and low %VC (85 ≤ C2 < 90, OR = 1.40; 90 ≤ C3 < 95, OR = 1.55; 95 ≤ C4, OR = 2.51; relative to C1 < 85.0 cm). In women, BMI was significantly associated with low %VC in C3 and C4 (C3, OR = 2.05; C4, OR = 2.84), and WC was significantly associated with low %VC in C4 (C4, OR = 2.32).
  
  
  CONCLUSIONS
  Our results suggest that obesity may be associated with restrictive pulmonary function and underscore the importance of maintaining ideal body weight for the prevention of restrictive pulmonary dysfunction.
authors.affiliation: Department of General Medicine, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Goto
authors.forename: Hirohide
authors.initials: H
authors.lastname: Yokokawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fukuda
authors.forename: Toshio
authors.initials: T
authors.lastname: Naito
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Hisaoka
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Isonuma
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D050171:Dyslipidemias / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000209:etiology; D007564:Japan / Q000453:epidemiology; D008019:Life Style; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D014797:Vital Capacity; D055105:Waist Circumference