title: Quantitative microbial risk assessment of Cryptosporidium and Giardia in well water from a native community of Mexico.
abstract: Cryptosporidium and Giardia are gastrointestinal disease-causing organisms transmitted by the fecal-oral route, zoonotic and prevalent in all socioeconomic segments with greater emphasis in rural communities. The goal of this study was to assess the risk of cryptosporidiosis and giardiasis of Potam dwellers consuming drinking water from communal well water. To achieve the goal, quantitative microbial risk assessment (QMRA) was carried out as follows: (a) identification of Cryptosporidium oocysts and Giardia cysts in well water samples by information collection rule method, (b) assessment of exposure to healthy Potam residents, (c) dose-response modelling, and (d) risk characterization using an exponential model. All well water samples tested were positive for Cryptosporidium and Giardia. The QMRA results indicate a mean of annual risks of 99:100 (0.99) for cryptosporidiosis and 1:1 (1.0) for giardiasis. The outcome of the present study may drive decision-makers to establish an educational and treatment program to reduce the incidence of parasite-borne intestinal infection in the Potam community, and to conduct risk analysis programs in other similar rural communities in Mexico.
authors.affiliation: a Departamento de Biotecnología y Ciencias Alimentarias , Instituto Tecnológico de Sonora (ITSON) , Cd. Obregón , Mexico.
authors.forename: Ana Paola
authors.initials: AP
authors.lastname: Balderrama-Carmona
authors.forename: Pablo
authors.initials: P
authors.lastname: Gortáres-Moroyoqui
authors.forename: Luis Humberto
authors.initials: LH
authors.lastname: Álvarez-Valencia
authors.forename: Luciano
authors.initials: L
authors.lastname: Castro-Espinoza
authors.forename: José de Jesús
authors.initials: Jde J
authors.lastname: Balderas-Cortés
authors.forename: Iram
authors.initials: I
authors.lastname: Mondaca-Fernández
authors.forename: Cristóbal
authors.initials: C
authors.lastname: Chaidez-Quiroz
authors.forename: María Mercedes
authors.initials: MM
authors.lastname: Meza-Montenegro
mesh_terms: D003457:Cryptosporidiosis / Q000453:epidemiology* / Q000382:microbiology; D003458:Cryptosporidium / Q000302:isolation & purification*; D005872:Giardia / Q000302:isolation & purification*; D005873:Giardiasis / Q000453:epidemiology* / Q000382:microbiology; D060587:Groundwater / Q000382:microbiology*; D006801:Humans; D007198:Indians, North American; D008800:Mexico / Q000453:epidemiology; D018570:Risk Assessment; D060986:Water Wells
keywords: Yaquis; cryptosporidiosis; giardiasis; parasites occurrence