title: Linear dialdehydes as promising substrates for aminocatalyzed transformations.
abstract: Organocatalytic domino reactions involving amine activation of carbonyl compounds have become the latest chemical technology towards the design and development of useful synthetic methods. In this direction, linear dialdehydes such as succinaldehyde, glutaraldehyde, and other homologous compounds have attracted considerable attention as suitable substrates for amine catalyzed transformations. Due to their unique structural features, dialdehydes can easily engage in recreation of cascade/tandem transformations for the synthesis of valuable natural products and drug molecules. In this review article we discuss the current scenario and potential applications of linear dialdehydes as adequate synthetic substrates for amine catalyzed transformations to access biologically important complex scaffolds.
authors.affiliation: Department of Chemistry, Birla Institute of Technology and Science-Pilani, Pilani Campus, 333 031, Rajasthan, India. indresh.chemistry@gmail.com indresh.kumar@pilani.bits-pilani.ac.in.
authors.forename: Indresh
authors.initials: I
authors.lastname: Kumar
authors.forename: Panduga
authors.initials: P
authors.lastname: Ramaraju
authors.forename: Nisar A
authors.initials: NA
authors.lastname: Mir
authors.forename: Anoop
authors.initials: A
authors.lastname: Singh