title: [Comparative study of transient elastography versus real-time tissue elastography for assessment of liver fibrosis in patients with chronic liver disease].
abstract: OBJECTIVE
  To compare the abilities of transient elastography (TE) versus real-time tissue elastography (RTE) for assessing liver fibrosis in patients with chronic liver disease.
  
  
  METHODS
  Ninetytwo patients with chronic liver disease were enrolled in the study, and included 77 cases of chronic hepatitis B, 4 cases of chronic hepatitis C, 4 cases of autoimmune liver disease, 2 cases of primary biliary cirrhosis, I case of abnormal bile duct development, and 4 cases of unknown etiology.All patients were assessed by both TE and RTE in a single day.The correlation coefficient of liver fibrosis level and the receiver operating characteristic (ROC) curve of S more than 2 and =4 of TE and RTE were determined.The values were compared using findings fiom pathological analysis as reference.
  
  
  RESULTS
  The correlation coefficient of liver fibrosis level was significantly higher for TE (r =0.755, 95% CI:0.651-0.831, P =0.000) than for RTE (r=0.481, 95% CI:0.306-0.624, P =0.000) (Z=3.07, P =0.002).The areas under the ROC curves for S more than 2 and =4 were 0.903 and 0.740 for TE and 0.915 and 0.786 for RTE, respectively, indicating that the performance of TE was superior to that of RTE.
  
  
  CONCLUSIONS
  TE was superior to RTE for assessment of liver fibrosis.
authors.affiliation: Department of Ultrasound, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zheng
authors.forename: Lixin
authors.initials: L
authors.lastname: Yang
authors.forename: Tao
authors.initials: T
authors.lastname: Wu
authors.forename: Jie
authors.initials: J
authors.lastname: Zeng
authors.forename: Zeping
authors.initials: Z
authors.lastname: Huang
authors.forename: Bowen
authors.initials: B
authors.lastname: Zheng
authors.forename: Hongjun
authors.initials: H
authors.lastname: Zhang
authors.forename: Rongqin
authors.initials: R
authors.lastname: Zheng
mesh_terms: D001327:Autoimmune Diseases; D054459:Elasticity Imaging Techniques; D019694:Hepatitis B, Chronic / Q000000981:diagnostic imaging*; D019698:Hepatitis C, Chronic / Q000000981:diagnostic imaging*; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000000981:diagnostic imaging*; D012372:ROC Curve