title: Maternal immunization. Clinical experiences, challenges, and opportunities in vaccine acceptance.
abstract: Maternal immunization holds tremendous promise to improve maternal and neonatal health for a number of infectious conditions. The unique susceptibilities of pregnant women to infectious conditions, as well as the ability of maternally-derived antibody to offer vital neonatal protection (via placental transfer), together have produced the recent increased attention on maternal immunization. The Advisory Committee on Immunization Practices (ACIP) currently recommends 2 immunizations for all pregnant women lacking contraindication, inactivated Influenza and tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap). Given ongoing research the number of vaccines recommended during pregnancy is likely to increase. Thus, achieving high vaccination coverage of pregnant women for all recommended immunizations is a key public health enterprise. This review will focus on the present state of vaccine acceptance in pregnancy, with attention to currently identified barriers and determinants of vaccine acceptance. Additionally, opportunities for improvement will be considered.
authors.affiliation: a Robert Wood Johnson Foundation Clinical Scholars® Program; Department of Obstetrics and Gynecology; Institute for Healthcare Policy and Innovation ; University of Michigan ; Ann Arbor , MI USA.
authors.forename: Michelle H
authors.initials: MH
authors.lastname: Moniz
authors.forename: Richard H
authors.initials: RH
authors.lastname: Beigi
mesh_terms: D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000276:immunology; D004165:Diphtheria / Q000517:prevention & control; D005260:Female; D006801:Humans; D007112:Immunity, Maternally-Acquired; D007114:Immunization / Q000379:methods* / Q000706:statistics & numerical data*; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000276:immunology; D007251:Influenza, Human / Q000517:prevention & control; D010342:Patient Acceptance of Health Care; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control*; D013742:Tetanus / Q000517:prevention & control; D014917:Whooping Cough / Q000517:prevention & control
chemical_list: D001428:Bacterial Vaccines; D007252:Influenza Vaccines
keywords: AAP, American Academy of Pediatrics; ACIP, Advisory Committee on Immunization Practices; ACOG, American College of Obstetricians and Gynecologists; CDC, Centers for Disease Control and Prevention; MMR, measles, mumps, and rubella; Tdap, tetanus toxoid, reduced diphtheria toxoid and acellular pertussis; immunization; influenza; pertussis; pregnancy; vaccination; vaccine