title: [Effect of blood lipid on the change of brachial-ankle pulse wave velocity among prehypertensive population].
abstract: OBJECTIVE
  To explore the effect of blood lipid and lipoprotein ratios on the change of brachial-ankle pulse wave velocity (baPWV) among prehypertensive subjects.
  
  
  METHODS
  11 611 subjects with normal blood pressure (BP) were divided into two groups, which was one with optimal blood pressure (BP<120/80 mmHg) and the other with prehypertension (BP:120-139/80-89 mmHg). Height, weight, baPWV, fasting blood-glucose, TC, TG, LDL-C and HDL-C were detected.
  
  
  RESULTS
  The abnormal rate of baPWV in prehypertension group was obviously higher than that in the optimal blood pressure group. For optimal blood pressure group, the abnormality of TG, TC, LDL-C, TC/HDL-C as well as LDL-C/HDL-C, caused the increase of baPWV significantly (P < 0.001). For prehypertensive group, the abnormality of TC and LDL-C caused the significant increase of baPWV (P < 0.001). Results from logistic regression analysis showed that except for age, BMI and fasting blood-glucose, TC/HDL-C increasing was the independent risk factor in optimal blood pressure group, while TG increasing was for the prehypertension group.
  
  
  CONCLUSIONS
  With different normal BP level, both abnormality of blood lipid and lipoprotein ratio were the independent risk factors for baPWV increasing.
authors.affiliation: Center of Health Physical Examination and Health Management, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
authors.affiliation: Center of Health Physical Examination and Health Management, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, China. Email: shuaiping012@163.com.
authors.forename: Ping
authors.initials: P
authors.lastname: Shuai
authors.affiliation: Center of Health Physical Examination and Health Management, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, China.
authors.forename: Yuping
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Center of Health Physical Examination and Health Management, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, China.
authors.forename: Youfu
authors.initials: Y
authors.lastname: Cheng
authors.affiliation: Center of Health Physical Examination and Health Management, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Yang
authors.affiliation: Center of Health Physical Examination and Health Management, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, China.
authors.forename: Tingxin
authors.initials: T
authors.lastname: Li
authors.affiliation: Center of Health Physical Examination and Health Management, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, China.
authors.forename: Lirong
authors.initials: L
authors.lastname: Gong
authors.affiliation: Center of Health Physical Examination and Health Management, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, China.
authors.forename: Jiaojiao
authors.initials: J
authors.lastname: Ren
authors.affiliation: Center of Health Physical Examination and Health Management, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, China.
authors.forename: Hongjia
authors.initials: H
authors.lastname: Wang