title: Marine nucleosides: structure, bioactivity, synthesis and biosynthesis.
abstract: Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review covers 68 marine originated nucleosides and their synthetic analogs published up to June 2014. The review will focus on the structures, bioactivities, synthesis and biosynthetic processes of these compounds.
authors.affiliation: Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. prsxs@bath.ac.uk.
authors.forename: Ri-Ming
authors.initials: RM
authors.lastname: Huang
authors.affiliation: College of Light Industry and Food Engineering, Guangxi University, Nanning 530004, China. chendianyu3356@163.com.
authors.forename: Yin-Ning
authors.initials: YN
authors.lastname: Chen
authors.affiliation: School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China. zzy205687@126.com.
authors.forename: Ziyu
authors.initials: Z
authors.lastname: Zeng
authors.affiliation: Key Laboratory of Marine Environmental Science, Guangxi Academy of Sciences, Nanning 530007, China. gaochenghai@gxas.cn.
authors.forename: Cheng-Hai
authors.initials: CH
authors.lastname: Gao
authors.affiliation: Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, UK. prsxs@bath.ac.uk.
authors.forename: Xiangdong
authors.initials: X
authors.lastname: Su
authors.affiliation: Life Science & Technology School, Lingnan Normal University, Zhanjiang 52048, China. py00_2006@126.com.
authors.forename: Yan
authors.initials: Y
authors.lastname: Peng
mesh_terms: D000818:Animals; D001685:Biological Factors / Q000096:biosynthesis* / Q000737:chemistry*; D006801:Humans; D008386:Marine Biology / Q000379:methods; D009705:Nucleosides / Q000096:biosynthesis* / Q000737:chemistry*; D009711:Nucleotides / Q000096:biosynthesis / Q000737:chemistry
chemical_list: D001685:Biological Factors; D009705:Nucleosides; D009711:Nucleotides