title: Measurement of endolymphatic pressure.
abstract: Endolymphatic pressure measurement is of interest both to researchers in the physiology and pathophysiology of hearing and ENT physicians dealing with Menière's disease or similar conditions. It is generally agreed that endolymphatic hydrops is associated with Menière's disease and is accompanied by increased hydrostatic pressure. Endolymphatic pressure, however, cannot be measured precisely without endangering hearing, making the association between hydrops and increased endolymphatic pressure difficult to demonstrate. Several integrated in vivo models have been developed since the 1960s, but only a few allow measurement of endolymphatic hydrostatic pressure. Models associating measurement of hydrostatic pressure and endolymphatic potential and assessment of cochlear function are of value to elucidate the pathophysiology of endolymphatic hydrops. The present article presents the main types of models and discusses their respective interest.
authors.affiliation: Service d'ORL et de chirurgie cervicofaciale, hôpital Gabriel-Montpied, CHU, 30, place Henri-Dunant, 63000 Clermont-Ferrand, France; Laboratoire de biophysique neurosensorielle, UMR Inserm 1107, faculté de médecine, université Auvergne-Clermont 1, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France. Electronic address: tmom@chu-clermontferrand.fr.
authors.forename: T
authors.initials: T
authors.lastname: Mom
authors.affiliation: Service d'ORL et de chirurgie cervicofaciale, hôpital Gabriel-Montpied, CHU, 30, place Henri-Dunant, 63000 Clermont-Ferrand, France; Laboratoire de biophysique neurosensorielle, UMR Inserm 1107, faculté de médecine, université Auvergne-Clermont 1, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Pavier
authors.affiliation: Laboratoire de biophysique neurosensorielle, UMR Inserm 1107, faculté de médecine, université Auvergne-Clermont 1, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: F
authors.initials: F
authors.lastname: Giraudet
authors.affiliation: Service d'ORL et de chirurgie cervicofaciale, hôpital Gabriel-Montpied, CHU, 30, place Henri-Dunant, 63000 Clermont-Ferrand, France; Laboratoire de biophysique neurosensorielle, UMR Inserm 1107, faculté de médecine, université Auvergne-Clermont 1, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: L
authors.initials: L
authors.lastname: Gilain
authors.affiliation: Laboratoire de biophysique neurosensorielle, UMR Inserm 1107, faculté de médecine, université Auvergne-Clermont 1, 28, place Henri-Dunant, 63000 Clermont-Ferrand, France.
authors.forename: P
authors.initials: P
authors.lastname: Avan
mesh_terms: D007758:Ear, Inner / Q000503:physiopathology*; D004710:Endolymph; D018159:Endolymphatic Hydrops / Q000175:diagnosis* / Q000503:physiopathology*; D019317:Evidence-Based Medicine; D034381:Hearing Loss / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D006874:Hydrostatic Pressure; D008575:Meniere Disease / Q000175:diagnosis / Q000503:physiopathology; D014724:Vestibular Function Tests / Q000379:methods
keywords: Endolymphatic potential; Hydrops; Hydrostatic pressure; Integrated models; Intralabyrinthine pressure