title: Iron-mediated Markovnikov-selective hydro-trifluoromethylthiolation of unactivated alkenes.
abstract: An iron-mediated hydro-trifluoromethylthiolation of unactivated olefins under mild conditions was described for the first time. The reaction occurred to full conversion within 30 min at 0 °C and tolerates a variety of functional groups. Preliminary mechanistic studies suggested that the reaction proceeds via a free-radical pathway.
authors.affiliation: Key Laboratory of Organofluorine Chemistry Laboratory, Shanghai Institute of Organic Chemistry, 345 Lingling Lu, Shanghai, 200032, China. lulong@sioc.ac.cn shenql@sioc.ac.cn.
authors.forename: Tao
authors.initials: T
authors.lastname: Yang
authors.forename: Long
authors.initials: L
authors.lastname: Lu
authors.forename: Qilong
authors.initials: Q
authors.lastname: Shen
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry*; D058085:Iron Compounds / Q000737:chemistry*; D008745:Methylation; D015394:Molecular Structure; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D000475:Alkenes; D058085:Iron Compounds; D013438:Sulfhydryl Compounds; D005461:Fluorine