title: How ketamine helps to overcome depression.
abstract: Genetically modified mice shed new light on how ketamine can target NMDA receptors in the brain to reduce the symptoms of depression.
authors.affiliation: Center for Neural Science, New York University, New York, United States.
authors.forename: Thu N
authors.initials: TN
authors.lastname: Huynh
authors.affiliation: Center for Neural Science, New York University, New York, United States ek65@nyu.edu.
authors.forename: Eric
authors.initials: E
authors.lastname: Klann
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001522:Behavior, Animal; D003863:Depression / Q000188:drug therapy* / Q000378:metabolism*; D007649:Ketamine / Q000627:therapeutic use*; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism*
chemical_list: D000928:Antidepressive Agents; D016194:Receptors, N-Methyl-D-Aspartate; D007649:Ketamine
keywords: cell biology; cortex; depression; electrophysiology; ketamine; mouse; neuroscience; protein synthesis; rat; synapse