title: Volumetric analysis of implanted biphasic calcium phosphate/collagen composite by three-dimensional cone beam computed tomography head model superimposition.
abstract: Facial onlay augmentation is often performed as an ancillary procedure simultaneously with orthognathic surgery to improve facial appearance, with hydroxyapatite (HAp) and HAp-based composites often used as the materials of choice. The ability to apply HAp in a granular rather than solid shape form may be responsible for its comparatively reduced rate of complications. However, a known complication of HAp and HAp composites is reduction of implant volume over time associated with resorption of the material. Evaluation of the volumetric changes of implanted biphasic calcium phosphate (HAp/β-TCP)/collagen composite in the malar areas from baseline to 4 months, 9-12 months, and 18-24 months after surgery using cone beam computed tomography (CBCT) surface superimposition and volumetric subtraction was done. The average decrease of volume of implanted HAp/β-TCP 4 months after surgery was 18.6%. Further volumetric decreases were negligible and a mean total volume loss of 21.65% was found at 18-24 months postoperatively.
authors.affiliation: Department of Maxillofacial Surgery, Vilnius University Zalgirio Hospital, Zalgirio Street 115, 117, Vilnius, LT 08217, Lithuania; Rudolfs Cimdins Riga Biomaterials Innovations and Development Center of Riga Technical University, Pulka Street 3, Riga, LV 1007, Latvia.
authors.forename: Simonas
authors.initials: S
authors.lastname: Grybauskas
authors.affiliation: Rudolfs Cimdins Riga Biomaterials Innovations and Development Center of Riga Technical University, Pulka Street 3, Riga, LV 1007, Latvia. Electronic address: janis.locs@rtu.lv.
authors.forename: Janis
authors.initials: J
authors.lastname: Locs
authors.affiliation: Institute of Stomatology, Riga Stradins University, Dzirciema Street 20, LV 1007, Latvia.
authors.forename: Ilze
authors.initials: I
authors.lastname: Salma
authors.affiliation: Institute of Stomatology, Riga Stradins University, Dzirciema Street 20, LV 1007, Latvia.
authors.forename: Girts
authors.initials: G
authors.lastname: Salms
authors.affiliation: Rudolfs Cimdins Riga Biomaterials Innovations and Development Center of Riga Technical University, Pulka Street 3, Riga, LV 1007, Latvia.
authors.forename: Liga
authors.initials: L
authors.lastname: Berzina-Cimdina
mesh_terms: D020341:Absorbable Implants; D018786:Bone Substitutes / Q000737:chemistry / Q000627:therapeutic use*; D002130:Calcium Phosphates / Q000737:chemistry / Q000627:therapeutic use*; D003094:Collagen / Q000737:chemistry / Q000627:therapeutic use*; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D006882:Hydroxyapatites / Q000737:chemistry / Q000627:therapeutic use*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D056948:Orthognathic Surgical Procedures / Q000379:methods; D010316:Particle Size; D016062:Porosity; D012189:Retrospective Studies; D017550:Spectroscopy, Fourier Transform Infrared; D013382:Subtraction Technique; D013499:Surface Properties; D014961:X-Ray Diffraction; D015050:Zygoma / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; D006882:Hydroxyapatites; C485817:beta-tricalcium phosphate; C094280:hydroxyapatite-tricalciumphosphate composite; D003094:Collagen
keywords: Bioresorption; Bone graft; Facial onlay augmentation; Superimposition; Volume analysis