title: Co(III)-catalyzed C-H activation/formal SN-type reactions: selective and efficient cyanation, halogenation, and allylation.
abstract: The first cobalt-catalyzed cyanation, halogenation, and allylation via C-H activation have been realized. These formal SN-type reactions generate valuable (hetero)aryl/alkenyl nitriles, iodides, and bromides as well as allylated indoles using a bench-stable Co(III) catalyst. High regio- and mono-selectivity were achieved for these reactions. Additionally, allylation proceeded efficiently with a turnover number of 2200 at room temperature, which is unprecedented for this Co(III) catalyst. Alkenyl substrates and amides have been successfully utilized in Cp*Co(III)-catalyzed C-H activation for the first time.
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster , Corrensstrasse 40, 48149 Münster, Germany.
authors.forename: Da-Gang
authors.initials: DG
authors.lastname: Yu
authors.forename: Tobias
authors.initials: T
authors.lastname: Gensch
authors.forename: Francisco
authors.initials: F
authors.lastname: de Azambuja
authors.forename: Suhelen
authors.initials: S
authors.lastname: Vásquez-Céspedes
authors.forename: Frank
authors.initials: F
authors.lastname: Glorius