title: Antibiotics in typical marine aquaculture farms surrounding Hailing Island, South China: occurrence, bioaccumulation and human dietary exposure.
abstract: The occurrence, bioaccumulation, and human dietary exposure via seafood consumption of 37 antibiotics in six typical marine aquaculture farms surrounding Hailing Island, South China were investigated in this study. Sulfamethoxazole, salinomycin and trimethoprim were widely detected in the water samples (0.4-36.9 ng/L), while oxytetracycline was the predominant antibiotic in the water samples of shrimp larvae pond. Enrofloxacin was widely detected in the feed samples (16.6-31.8 ng/g) and erythromycin-H2O was the most frequently detected antibiotic in the sediment samples (0.8-4.8 ng/g). Erythromycin-H2O was the dominant antibiotic in the adult Fenneropenaeus penicillatus with concentrations ranging from 2498 to 15,090 ng/g. In addition, trimethoprim was found to be bioaccumulative in young Lutjanus russelli with a median bioaccumulation factor of 6488 L/kg. Based on daily intake estimation, the erythromycin-H2O in adult F. penicillatus presented a potential risk to human safety.
authors.affiliation: Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; University of Chinese Academy of Sciences, Beijing 100049, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.affiliation: Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China; State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China.
authors.forename: Shan
authors.initials: S
authors.lastname: Liu
authors.affiliation: Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China. Electronic address: xuxr@scsio.ac.cn.
authors.forename: Xiang-Rong
authors.initials: XR
authors.lastname: Xu
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China; University of Chinese Academy of Sciences, Beijing 100049, China.
authors.forename: Shuang-Shuang
authors.initials: SS
authors.lastname: Liu
authors.affiliation: Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
authors.forename: Guang-Jie
authors.initials: GJ
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Tropical Marine Bio-Resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
authors.forename: Kai-Feng
authors.initials: KF
authors.lastname: Sun
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China.
authors.forename: Jian-Liang
authors.initials: JL
authors.lastname: Zhao
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China.
authors.forename: Guang-Guo
authors.initials: GG
authors.lastname: Ying
mesh_terms: D000821:Animal Feed; D000900:Anti-Bacterial Agents / Q000032:analysis*; D017756:Aquaculture; D002681:China; D004032:Diet; D004784:Environmental Monitoring; D019015:Geologic Sediments / Q000737:chemistry; D006801:Humans; D062312:Islands; D017747:Seafood; D012623:Seawater / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; D014874:Water Pollutants, Chemical
keywords: Antibiotics; Bioaccumulation; Hailing Island; Human dietary exposure; Marine aquaculture