title: A regularized relaxed ordered subset list-mode reconstruction algorithm and its preliminary application to undersampling PET imaging.
abstract: List mode format is commonly used in modern positron emission tomography (PET) for image reconstruction due to certain special advantages. In this work, we proposed a list mode based regularized relaxed ordered subset (LMROS) algorithm for static PET imaging. LMROS is able to work with regularization terms which can be formulated as twice differentiable convex functions. Such a versatility would make LMROS a convenient and general framework for fulfilling different regularized list mode reconstruction methods. LMROS was applied to two simulated undersampling PET imaging scenarios to verify its effectiveness. Convex quadratic function, total variation constraint, non-local means and dictionary learning based regularization methods were successfully realized for different cases. The results showed that the LMROS algorithm was effective and some regularization methods greatly reduced the distortions and artifacts caused by undersampling.
authors.affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China.
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Cao
authors.forename: Qingguo
authors.initials: Q
authors.lastname: Xie
authors.forename: Peng
authors.initials: P
authors.lastname: Xiao
mesh_terms: D000465:Algorithms; D016477:Artifacts; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging*; D019047:Phantoms, Imaging; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals
chemical_list: D019275:Radiopharmaceuticals