title: Patient-specific simulation of implant placement and function for cochlear implantation surgery planning.
abstract: We present a framework for patient specific electrical stimulation of the cochlea, that allows to perform in-silico analysis of implant placement and function before surgery. A Statistical Shape Model (SSM) is created from high-resolution human μCT data to capture important anatomical details. A Finite Element Model (FEM) is built and adapted to the patient using the results of the SSM. Electrical simulations based on Maxwell's equations for the electromagnetic field are performed on this personalized model. The model includes implanted electrodes and nerve fibers. We present the results for the bipolar stimulation protocol and predict the voltage spread and the locations of nerve excitation.
authors.forename: Mario
authors.initials: M
authors.lastname: Ceresa
authors.forename: Nerea Mangado
authors.initials: NM
authors.lastname: Lopez
authors.forename: Hector Dejea
authors.initials: HD
authors.lastname: Velardo
authors.forename: Noemi Carranza
authors.initials: NC
authors.lastname: Herrezuelo
authors.forename: Pavel
authors.initials: P
authors.lastname: Mistrik
authors.forename: Hans Martin
authors.initials: HM
authors.lastname: Kjer
authors.forename: Sergio
authors.initials: S
authors.lastname: Vera
authors.forename: Rasmus R
authors.initials: RR
authors.lastname: Paulsen
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: González Ballester
mesh_terms: D003051:Cochlea / Q000000981:diagnostic imaging* / Q000601:surgery; D019929:Cochlear Implantation / Q000379:methods*; D003198:Computer Simulation; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods; D008953:Models, Anatomic; D008954:Models, Biological; D066230:Patient-Specific Modeling; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D025321:Surgery, Computer-Assisted / Q000379:methods*