title: Metastasis to the proximal ureter from prostatic adenocarcinoma: A rare metastatic pattern.
abstract: Prostate cancer is one of the most common male malignancies, but it rarely metastasizes to the proximal ureter. We report a case of a 76-year-old man who presented with flank pain and lower urinary tract symptoms. Abdominal computed tomography scan revealed multiple filling defects at the middle of the left ureter, enlarged retroperitoneal lymph nodes, and probable psoas invasion. The patient underwent nephroureterectomy with excision of a cuff of bladder, and was found to have an adhesion between the middle part of left ureter and psoas intraoperatively. The pathological examination displayed positive immunohistochemical staining with prostate-specific antigen and prostate acid phostate, supporting the diagnosis of metastatic ureteral tumour from prostate cancer. In this case, periureteral soft tissue and ureteral muscular layer were infiltrated by metastatic tumour, whereas the mucosa was spared. The periureteral lymphatic pathway played an important role in the metastatic procedure of prostate cancer to the proximal ureter.
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Min
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Dexin
authors.initials: D
authors.lastname: Yu
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Dongdong
authors.initials: D
authors.lastname: Xie
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Demao
authors.initials: D
authors.lastname: Ding
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Ci
authors.initials: C
authors.lastname: Zou
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Urology, The Second Hospital of Anhui Medical University, China.
authors.forename: Daming
authors.initials: D
authors.lastname: Wang