title: Structures of eremophilane-type sesquiterpene glucosides, alticolosides A-G, from the Far Eastern endemic Ligularia alticola Worosch.
abstract: Seven eremophilane-type sesquiterpene glucosides, alticolosides A-G, have been isolated from aerial parts of the endemic Far Eastern species Ligularia alticola Worosch. (Family Asteraceae) along with two known compounds, monoterpenoid glycoside (4S)-α-terpineol 8-O-β-D-glucopyranoside and norditerpenoid glycoside 7(8)-dihydro-β-ionone 3-O-β-D-glucopyranoside. Alticoloside D was identified with the earlier known 8-O-(β-D-glucopyranosyl)-2-oxo-eremophila-1(10),8,11-triene, but the stereostructure of the latter was revised on the basis of ROESY and CD data. All the glycosides are derivatives of new eremophilane-type aglycones, differing from known eremophilanes in details of planar and/or stereo structures except for the aglycone of alticoloside E.
authors.affiliation: G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022 Vladivostok, Russian Federation. Electronic address: sialexandra@mail.ru.
authors.forename: Alexandra S
authors.initials: AS
authors.lastname: Silchenko
authors.affiliation: G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022 Vladivostok, Russian Federation.
authors.forename: Anatoly I
authors.initials: AI
authors.lastname: Kalinovsky
authors.affiliation: G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022 Vladivostok, Russian Federation.
authors.forename: Ludmila P
authors.initials: LP
authors.lastname: Ponomarenko
authors.affiliation: G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022 Vladivostok, Russian Federation.
authors.forename: Sergey A
authors.initials: SA
authors.lastname: Avilov
authors.affiliation: G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022 Vladivostok, Russian Federation.
authors.forename: Pelageya V
authors.initials: PV
authors.lastname: Andryjaschenko
authors.affiliation: G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022 Vladivostok, Russian Federation.
authors.forename: Pavel S
authors.initials: PS
authors.lastname: Dmitrenok
authors.affiliation: G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022 Vladivostok, Russian Federation.
authors.forename: Peter G
authors.initials: PG
authors.lastname: Gorovoy
authors.affiliation: G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022 Vladivostok, Russian Federation.
authors.forename: Natalia Yu
authors.initials: NY
authors.lastname: Kim
authors.affiliation: G.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch, Russian Academy of Sciences, Pr. 100-letya Vladivostoka 159, 690022 Vladivostok, Russian Federation.
authors.forename: Valentin A
authors.initials: VA
authors.lastname: Stonik
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification; D045792:Norisoprenoids / Q000737:chemistry / Q000302:isolation & purification; D019906:Nuclear Magnetic Resonance, Biomolecular; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004224:Diterpenes; D005960:Glucosides; D039821:Monoterpenes; D045792:Norisoprenoids; D012717:Sesquiterpenes; C008157:beta-ionone
keywords: Alticolosides; Ligularia alticola; NMR; Sesquiterpene eremophilane-type glycosides