title: Radical-polar crossover reactions: oxidative coupling of 1,3-dioxolanes with electron-deficient alkenes and vinylarenes based on a radical addition and Kornblum-DeLaMare rearrangement.
abstract: A new radical-polar crossover reaction has been developed involving the combination of a tandem radical reaction and Kornblum-DeLaMare rearrangement in a one-pot process. This simple methodology allows for the construction of polyfunctionalized carbonyl compounds via the oxidative coupling of 1,3-dioxolanes with electron-deficient alkenes and vinylarenes in the presence of Co(salen) and TBHP under mild conditions. This reaction also exhibited high functional group tolerance, wide substrate scope, and operational simplicity.
authors.affiliation: Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University , Suzhou 215123, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Du
authors.forename: Huihuang
authors.initials: H
authors.lastname: Li
authors.forename: Yaxiong
authors.initials: Y
authors.lastname: Wang
authors.forename: Jiang
authors.initials: J
authors.lastname: Cheng
authors.forename: Xiaobing
authors.initials: X
authors.lastname: Wan