title: Comparison between two metabolic monitors in the measurement of resting energy expenditure and oxygen consumption in diabetic and non-diabetic ambulatory and hospitalized patients.
abstract: OBJECTIVE
  The aim of this study was to assess the validity and reliability of the Fitmate metabolic system in measuring the oxygen consumption and resting metabolic rate (RMR) in ambulatory and hospitalized patients.
  
  
  METHODS
  We conducted a prospective simultaneous clinical comparison. We enrolled 37 patients (19 women and 18 men) for the four groups of the study. Group 1 (n = 12) included patients receiving home parenteral nutrition. Group 2 (n = 5) included diabetic overweight outpatients with body mass index >30 kg/m(2) and hemoglobin A1c > 8 g/dL. Group 3 (n = 10) included hospitalized patients receiving artificial nutrition. Group 4 (n = 10) included patients with congenital heart disease, pulmonary hypertension of any etiology, and other heart disease who have had hemodynamic evaluation during catheterization by the adult congenital team. The patients were tested successively during the same session using the Fitmate metabolic system for 15 min and the Deltatrac II metabolic monitor for 20 min, measuring resting energy expenditure and oxygen consumption. The test was conducted in random order.
  
  
  RESULTS
  No significant differences were found between Fit Mate and Deltatrac II for oxygen consumption (238 ± 18 and 240 ± 18 mL/min, respectively, P = 0.72, r = 0.86, mean ± SD absolute difference 22.32 ± 16.99 mL/min) or RMR (1659 ± 122.34 and 1625 ± 118.4 kcal/d, P = 0.28, r = 0.87, mean ± SD absolute difference 152.9 ± 111.95 kcal/d). A degree of limit of agreement (403 kcal) was observed using the Bland-Altman test. When compared with Harris-Benedict predictive equations, Fitmate was found to be superior in accuracy.
  
  
  CONCLUSIONS
  These data indicate that the Fitmate using a mask provided a fair evaluation of REE despite a large limit of agreement. It remains a reliable and valid system for measuring oxygen consumption and RMR in nonventilated patients.
authors.affiliation: Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Tel-Aviv, Israel.
authors.forename: Liad
authors.initials: L
authors.lastname: Lupinsky
authors.affiliation: Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Tel-Aviv, Israel. Electronic address: Psinger@clalit.org.il.
authors.forename: Pierre
authors.initials: P
authors.lastname: Singer
authors.affiliation: Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Tel-Aviv, Israel.
authors.forename: Miriam
authors.initials: M
authors.lastname: Theilla
authors.affiliation: Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Tel-Aviv, Israel.
authors.forename: Milana
authors.initials: M
authors.lastname: Grinev
authors.affiliation: Department of Cardiology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Tel-Aviv, Israel.
authors.forename: Raphael
authors.initials: R
authors.lastname: Hirsh
authors.affiliation: Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Tel-Aviv, Israel.
authors.forename: Shaul
authors.initials: S
authors.lastname: Lev
authors.affiliation: Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Tel-Aviv, Israel.
authors.forename: Ilya
authors.initials: I
authors.lastname: Kagan
authors.affiliation: Institute of Endocrinology, Diabetes Services, Rabin Medical Center, Beilinson Campus, Petah Tiqva, Tel-Aviv, Israel.
authors.forename: Joelle
authors.initials: J
authors.lastname: Attal-Singer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001481:Basal Metabolism; D015992:Body Mass Index; D003920:Diabetes Mellitus / Q000378:metabolism*; D002149:Energy Intake; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption; D011446:Prospective Studies; D015203:Reproducibility of Results; D055815:Young Adult
chemical_list: D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human
keywords: Diabetic patients; Hospitalized patients; Metabolic monitor; Resting energy expenditure