title: Afebrile meningoencephalitis with transient central facial paralysis due to Toscana virus infection, southeastern France, 2014 [corrected].
abstract: We report a case of meningoencephalitis caused by Toscana virus (TOSV) with central facial paralysis lasting over two days acquired in south-eastern France. The patient was not febrile either before or during the course of the disease. The diagnosis was established by both real-time RT-PCR and virus isolation with complete genome sequencing. This case emphasises the need to consider TOSV in non-febrile neurological syndromes in people living in or having travelled to the Mediterranean area.
authors.affiliation: IHU Mediterranee Infection, APHM Public Hospitals of Marseille, Marseille, France.
authors.forename: Mc
authors.initials: M
authors.lastname: Marlinge
authors.forename: L
authors.initials: L
authors.lastname: Crespy
authors.forename: C
authors.initials: C
authors.lastname: Zandotti
authors.forename: G
authors.initials: G
authors.lastname: Piorkowski
authors.forename: E
authors.initials: E
authors.lastname: Kaphan
authors.forename: R N
authors.initials: RN
authors.lastname: Charrel
authors.forename: L
authors.initials: L
authors.lastname: Ninove
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002044:Bunyaviridae Infections / Q000175:diagnosis* / Q000188:drug therapy; D002443:Ceftriaxone / Q000627:therapeutic use; D005158:Facial Paralysis / Q000209:etiology*; D005260:Female; D005602:France; D016679:Genome, Viral / Q000235:genetics; D006801:Humans; D007303:Insect Vectors / Q000821:virology; D008590:Meningoencephalitis / Q000175:diagnosis* / Q000821:virology; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D020133:Reverse Transcriptase Polymerase Chain Reaction; D029301:Sandfly fever Naples virus / Q000235:genetics / Q000302:isolation & purification*; D017423:Sequence Analysis, RNA; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000998:Antiviral Agents; D012367:RNA, Viral; D002443:Ceftriaxone; D000658:Amoxicillin; D000212:Acyclovir