title: Methemoglobinemia due to quinine causing severe acute kidney injury in a child.
abstract: Congenital methemoglobinemia is a rare condition resulting from a deficiency of nicotinamide adenine dinucleotide-cytochrome b5 reductase. Acquired methemoglobinemia may result due to certain drugs, chemicals and food items. Information on epidemiological determinants from India is sparse. This report describes methemoglobinemia in a 4-year-old child after parenteral administration of quinine causing acute kidney injury. This case emphasizes the need of awareness of potential adverse events of antimalarial drugs. Prompt management of methemoglobinemia is essential to avoid potential life-threatening complications.
authors.affiliation: Department of Pediatrics, The Medicity Hospital, Gurgaon, Haryana, India.
authors.forename: S
authors.initials: S
authors.lastname: Kudale
authors.affiliation: Kidney Institute, Medanta, The Medicity Hospital, Gurgaon, Haryana, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Sethi
authors.affiliation: Department of Pediatric Intensive Care, The Medicity Hospital, Gurgaon, Haryana, India.
authors.forename: M
authors.initials: M
authors.lastname: Dhaliwal
authors.affiliation: Kidney Institute, Medanta, The Medicity Hospital, Gurgaon, Haryana, India.
authors.forename: V
authors.initials: V
authors.lastname: Kher
keywords: Acute kidney injury; methemoglobinemia; quinine