title: Association of body fat and vitamin D status and the effect of body fat on the response to vitamin D supplementation in Pakistani immigrants in Denmark.
abstract: Vitamin D deficiency and obesity are both prevalent conditions in the northern countries, especially among immigrants. The aims were to assess the possible relationship between body fat and vitamin D status, and to investigate the effect of body fat on the response to oral vitamin D supplementation in Pakistani immigrants in Denmark. Data were obtained from a 1-year double-blind randomised controlled trial with oral vitamin D supplementation. A total of 122 women and men received either vitamin D3 supplementation (10 or 20 μg/day) or placebo. No association was found between body fat percentage and vitamin D status in a multiple linear regression model (P<0.001). No effect of body fat was seen on the vitamin D status response following the intervention with vitamin D. In conclusion, there was no baseline association between body fat percentage and vitamin D status, and body fat percentage had no effect on the response to vitamin D supplementation.
authors.affiliation: Division of Nutrition, National Food Institute, Technical University of Denmark, Søborg, Denmark.
authors.forename: I M
authors.initials: IM
authors.lastname: Grønborg
authors.affiliation: Division of Nutrition, National Food Institute, Technical University of Denmark, Søborg, Denmark.
authors.forename: I M
authors.initials: IM
authors.lastname: Lundby
authors.affiliation: Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.
authors.forename: C
authors.initials: C
authors.lastname: Mølgaard
authors.affiliation: Division of Food Chemistry, National Food Institute, Technical University of Denmark, Søborg, Denmark.
authors.forename: J
authors.initials: J
authors.lastname: Jakobsen
authors.affiliation: Department of Medicine, Slagelse Sygehus, Slagelse, Denmark.
authors.forename: L
authors.initials: L
authors.lastname: Ovesen
authors.affiliation: Division of Nutrition, National Food Institute, Technical University of Denmark, Søborg, Denmark.
authors.forename: R
authors.initials: R
authors.lastname: Andersen
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D000328:Adult; D001823:Body Composition; D002762:Cholecalciferol / Q000494:pharmacology* / Q000627:therapeutic use; D003718:Denmark; D019587:Dietary Supplements; D004311:Double-Blind Method; D054242:Emigrants and Immigrants; D005260:Female; D006801:Humans; D016014:Linear Models; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000150:complications* / Q000208:ethnology; D010154:Pakistan; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood* / Q000150:complications / Q000188:drug therapy / Q000208:ethnology; D014815:Vitamins / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D014815:Vitamins; D014807:Vitamin D; D002762:Cholecalciferol; C104450:25-hydroxyvitamin D