title: Liver transplantation using grafts with rare metabolic disorders.
abstract: Metabolic diseases that involve the liver represent a heterogeneous group of disorders. Apart from the metabolic defect, the subject's liver functions may be normal. With the increasing need for organs, livers from donors with metabolic diseases other than familial amyloid polyneuropathy might be possibly used for transplantation. However, whether such livers qualify as grafts and how they might impact recipient outcome are still unanswered questions. This review of the literature summarizes current experience in the use of such grafts in the context of cadaveric, domino, and living-related liver transplantation.
authors.affiliation: AP-HP, Department of Hepatobiliary Surgery and Liver Transplantation, Hôpital La Pitié - Salpêtrière, Paris, France. Electronic address: astrid.schielke@psl.aphp.fr.
authors.forename: Astrid
authors.initials: A
authors.lastname: Schielke
authors.affiliation: AP-HP, Department of Hepatogastroenterology, Hôpital La Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, 47-83 Boulevard de l'Hôpital, Paris, France; Université Pierre et Marie Curie, 4 Place Jussieu, Paris, France. Electronic address: filomena.conti@psl.aphp.fr.
authors.forename: Filomena
authors.initials: F
authors.lastname: Conti
authors.affiliation: AP-HP, Department of Hepatobiliary Surgery and Liver Transplantation, Hôpital La Pitié - Salpêtrière, Paris, France. Electronic address: clairegoumard@hotmail.fr.
authors.forename: Claire
authors.initials: C
authors.lastname: Goumard
authors.affiliation: AP-HP, Department of Hepatobiliary Surgery and Liver Transplantation, Hôpital La Pitié - Salpêtrière, Paris, France. Electronic address: fabiano.perdigao@psl.aphp.fr.
authors.forename: Fabiano
authors.initials: F
authors.lastname: Perdigao
authors.affiliation: AP-HP, Department of Hepatogastroenterology, Hôpital La Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, 47-83 Boulevard de l'Hôpital, Paris, France; Université Pierre et Marie Curie, 4 Place Jussieu, Paris, France. Electronic address: yvon.calmus@psl.aphp.fr.
authors.forename: Yvon
authors.initials: Y
authors.lastname: Calmus
authors.affiliation: AP-HP, Department of Hepatobiliary Surgery and Liver Transplantation, Hôpital La Pitié - Salpêtrière, Paris, France; Université Pierre et Marie Curie, 4 Place Jussieu, Paris, France. Electronic address: olivier.scatton@psl.aphp.fr.
authors.forename: Olivier
authors.initials: O
authors.lastname: Scatton
mesh_terms: D058625:End Stage Liver Disease / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008659:Metabolic Diseases / Q000235:genetics / Q000601:surgery*; D035583:Rare Diseases; D009927:Tissue and Organ Procurement / Q000379:methods*
keywords: Liver transplantation; Rare hereditary metabolic disorders; Unusual grafts