title: Predicting PSR filters by transverse relaxation enhancements.
abstract: The paramagnetic spin relaxation (PSR) filter allows the suppression of the NMR resonances of individual components in mixtures according to their Gd(3+)-complexing ability. The difficulty in predicting this property hampers, however, the widespread application of this filter. Herein we describe that the PSR filter is dominated by the transverse relaxation enhancement (R(2p)) experienced by nuclei in the presence of Gd(3+), so that R(2p) represents a reliable predictive tool of suppression in the 1D and 2D PSR filter of complex mixtures. The robustness of R(2p) as a predictive tool in PSR filters has been demonstrated at different magnetic fields and for the (1)H, (13)C, COSY, and HMQC filtering of commercial multicomponent compositions, including beverages and drugs.
authors.affiliation: Department of Organic Chemistry and Center for Research in Biological Chemistry and Molecular Materials (CIQUS), University of Santiago de Compostela , Jenaro de la Fuente s/n, 15782 Santiago de Compostela, Spain.
authors.forename: Juan
authors.initials: J
authors.lastname: Correa
authors.forename: Luiz F
authors.initials: LF
authors.lastname: Pinto
authors.forename: Ricardo
authors.initials: R
authors.lastname: Riguera
authors.forename: Eduardo
authors.initials: E
authors.lastname: Fernandez-Megia