title: Retroperitoneal nongestational choriocarcinoma in a 25-year-old woman.
abstract: Choriocarcinoma is a highly invasive and metastatic neoplasm which arises in women of reproductive age. It can be either gestational or nongestational in origin, but the latter form is very rare. Choriocarcinoma is characterized by the production of human chorionic gonadotropin. It can metastasize to distant organs such as lung, brain, liver, kidney, and vagina in the early stages of disease, but retroperitoneal metastasis is extremely rare. Treatment options include surgical intervention and chemotherapy. We present the case of a 25-year-old nulliparous woman who presented to our department with a retroperitoneal mass and negative urine human chorionic gonadotropin test, who was immunohistopathologically diagnosed with nongestational choriocarcinoma. The patient responded well to surgery and multi-drug chemotherapy.
authors.affiliation: Department of Obstetrics and Gynecology, Ewha Womans University Global Top 5 Research Program, Ewha Womans University School of Medicine, Seoul, Korea.
authors.forename: Soo Yeon
authors.initials: SY
authors.lastname: Park
authors.affiliation: Department of Obstetrics and Gynecology, Ewha Womans University Global Top 5 Research Program, Ewha Womans University School of Medicine, Seoul, Korea.
authors.forename: Da Eun
authors.initials: DE
authors.lastname: Lee
authors.affiliation: Department of Pathology, Ewha Womans University Global Top 5 Research Program, Ewha Womans University School of Medicine, Seoul, Korea.
authors.forename: Hee Jung
authors.initials: HJ
authors.lastname: Park
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Ewha Womans University Global Top 5 Research Program, Ewha Womans University School of Medicine, Seoul, Korea.
authors.forename: Kwan Chang
authors.initials: KC
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, Ewha Womans University Global Top 5 Research Program, Ewha Womans University School of Medicine, Seoul, Korea.
authors.forename: Yun Hwan
authors.initials: YH
authors.lastname: Kim
keywords: Chorionic gonadotropin; Nongestational choriocarcinoma; Retroperitoneum