title: International committee for monitoring assisted reproductive technologies: world report on assisted reproductive technologies, 2007.
abstract: OBJECTIVE
  To analyze information on assisted reproductive technology (ART) performed worldwide, and trends in outcomes over successive years.
  
  
  METHODS
  Cross-sectional survey on access, efficiency, and safety of ART procedures performed in 55 countries during 2007.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  Infertile women and men undergoing ART globally.
  
  
  METHODS
  Collection and analysis of international ART data.
  
  
  METHODS
  Number of cycles performed, by country and region, including pregnancies, single and multiple birth rates, and perinatal mortality.
  
  
  RESULTS
  Overall, >1,251,881 procedures with ART were reported, and resulted in 229,442 reported babies born. The availability of ART varied by country, from 12 to 4,140 treatments per million population. Of all aspiration cycles, 65.2% (400,617 of 614,540) were intracytoplasmic sperm injection. The overall delivery rate per fresh aspiration was 20.3%, and for frozen-embryo transfer (FET), 18.4%, with a cumulative delivery rate of 25.8%. With wide regional variations, single-embryo transfer represented 23.4% of fresh transfers, and the proportion of deliveries with twins and triplets from fresh transfers was 22.3% and 1.2%, respectively. The perinatal mortality rate was 19.9 per 1,000 births for fresh in vitro fertilization using intracytoplasmic sperm injection, and 9.6 per 1,000 for FET. The proportion of women aged ≥40 years increased to 19.8% from 15.5% in 2006.
  
  
  CONCLUSIONS
  The international trend toward <3 transferred embryos continued, as did the wider uptake of FET. This was achieved without compromising delivery rates. The application of ART for women aged >40 years was a major component of ART services in some regions and countries.
authors.affiliation: Department of Obstetrics and Gynaecology, Saitama Medical University, Moroyama, Japan. Electronic address: osamishr@saitama-med.ac.jp.
authors.forename: Osamu
authors.initials: O
authors.lastname: Ishihara
authors.affiliation: Palo Alto Medical Foundation Fertility Physicians of North California, San Jose, California.
authors.forename: G David
authors.initials: GD
authors.lastname: Adamson
authors.affiliation: Department of Obstetrics & Gynaecology, Groote Schuur Hopsital and Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
authors.forename: Silke
authors.initials: S
authors.lastname: Dyer
authors.affiliation: National Institute for Health and Medical Research, Gynecology, Obstetrics and Reproductive Medicine Unit, Cochin-Saint Vincent de Paul University Hospital, Paris, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: de Mouzon
authors.affiliation: Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
authors.forename: Karl G
authors.initials: KG
authors.lastname: Nygren
authors.affiliation: Faculty of Health, University of Technology, Sydney, Sydney, New South Wales, Australia.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Sullivan
authors.affiliation: Clinica las Condes and Program of Ethics and Public Policies in Human Reproduction, University Diego Portales, Santiago, Chile.
authors.forename: Fernando
authors.initials: F
authors.lastname: Zegers-Hochschild
authors.affiliation: Egyptian In Vitro Fertilization-Embryo Transfer Center, Cairo, Egypt.
authors.forename: Ragaa
authors.initials: R
authors.lastname: Mansour
mesh_terms: D000328:Adult; D026661:Clinical Trials Data Monitoring Committees / Q000592:standards* / Q000639:trends; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D038622:Internationality; D050498:Live Birth / Q000453:epidemiology; D008297:Male; D011247:Pregnancy; D027724:Reproductive Techniques, Assisted / Q000592:standards* / Q000639:trends; D058028:Research Report / Q000592:standards* / Q000639:trends; D014944:World Health Organization
keywords: ART; assisted reproductive technologies; frozen embryo transfer; multiple births; outcomes; registry; single embryo transfer