title: Two new pyrone derivatives from the plant endophytic fungus Exserohilum sp.
abstract: Two new a-pyrones, Exserolide G-H (1-2), together with one known metabolite, stemphypyrone (3), were isolated from the solid-substrate fermentation cultures of the plant endophytic fungus Exserohilum sp. The structures of the new compounds were elucidated primarily by analysis of NMR data. Compounds 1-3 were tested for cytotoxicity against a small panel of human carcinoma cell lines. Compound 1 showed cytotoxicity against HeLa, A549 and HCT116 cells.
authors.forename: Ruxin
authors.initials: R
authors.lastname: Li
authors.forename: Shubin
authors.initials: S
authors.lastname: Niu
authors.forename: Liangdong
authors.initials: L
authors.lastname: Guo
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D045325:HCT116 Cells; D006367:HeLa Cells; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D011753:Pyrones / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D011753:Pyrones