title: [Incidence of major lower limb amputation in Geneva: twenty-one years of observation].
abstract: Between 1990 and 2010 the incidence of major lowerlimb amputations (by definition any level of amputation above the foot) in the canton of Geneva was 10.02 per 100,000 inhabitants/ year. The analysis of various population groups revealed that the presence of diabetes increased the relative risk of amputation by a factor of 20, and age 65 years or older by a factor of 9. During this 21 years period we observed a gradual decline in the incidence of amputation and an increased age at the time of amputation, despite the increasing prevalence of diabetes and an aging population. This was a reflection on the efforts of primary and secon- dary prevention, initiated in the 1980s in which Geneva was a pioneer.
authors.forename: G A
authors.initials: GA
authors.lastname: Carmona
authors.forename: A
authors.initials: A
authors.lastname: Lacraz
authors.forename: P
authors.initials: P
authors.lastname: Hoffmeyer
authors.forename: M
authors.initials: M
authors.lastname: Assal
mesh_terms: D000367:Age Factors; D000368:Aged; D000671:Amputation, Surgical / Q000706:statistics & numerical data*; D048909:Diabetes Complications / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D035002:Lower Extremity; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D013557:Switzerland / Q000453:epidemiology