title: Tomographic imaging of fragmented cortical bone heteroimplant and methylmethacrylate in segmental bone defect of rabbit tibia.
abstract: OBJECTIVE
  To evaluate the performance of composites consisting of fragmented cortical bone heteroimplant in association with methylmethacrylate preserved in 98% glycerin, in segmental bone defect of rabbit tibia medial metaphysis.
  
  
  METHODS
  In this study were used twelve adult New Zealand rabbits, divided into three groups of four animals each: G30 (30 days), G60 (60 days) and G90 (90 days). The bone defects previously created in the tibia were filled with composites and both were evaluated by cone-beam computed tomography, immediately after surgery and after 30, 60, and 90 days.
  
  
  RESULTS
  The composites fulfilled and remained in the sites of bone defects in all cases and were not registered signals of infection, migration or rejection.
  
  
  CONCLUSIONS
  The implanted composites promoted the bone defects repair without signals of infection and/or rejection. The composites are one more option for bone defects repair.
authors.affiliation: Faculty of Veterinary Medicine, University of Cuiaba, Cuiaba, MT, Brazil.
authors.forename: Silvio Henrique de
authors.initials: SH
authors.lastname: Freitas
authors.affiliation: FMV, UNIC, Cuiaba, MT, Brazil.
authors.forename: Renata Gebara Sampaio
authors.initials: RG
authors.lastname: Dória
authors.affiliation: FMV, UNIC, Cuiaba, MT, Brazil.
authors.forename: Fábio de Souza
authors.initials: Fde S
authors.lastname: Mendonça
authors.affiliation: FMV, UNIC, Cuiaba, MT, Brazil.
authors.forename: Marcelo Diniz dos
authors.initials: MD
authors.lastname: Santos
authors.affiliation: Department of Pathology, Faculty of Agriculture and Veterinary Sciences, Sao Paulo State University Júlio de Mesquita Filho, Jaboticabal, SP, Brazil.
authors.forename: Jair Rodini
authors.initials: JR
authors.lastname: Engrácia Filho
authors.affiliation: Department of Surgery, Faculty of Veterinary Medicine and Animal Science, USP, Sao Paulo, SP, Brazil.
authors.forename: Atanásio Serafim
authors.initials: AS
authors.lastname: Vidane
authors.affiliation: Faculty of Odontology, UNIC, Cuiaba, MT, Brazil.
authors.forename: Alessandro Tadeu Corrêa
authors.initials: AT
authors.lastname: Marques
authors.affiliation: DMV, FZEA, USP, Pirassununga, SP, Brazil.
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: Ambrósio
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000627:therapeutic use*; D018786:Bone Substitutes / Q000627:therapeutic use*; D017102:Fracture Healing / Q000502:physiology*; D008768:Methylmethacrylates; D023421:Models, Animal; D011184:Postoperative Period; D011817:Rabbits; D013977:Tibia / Q000000981:diagnostic imaging / Q000601:surgery*; D013978:Tibial Fractures / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes; D008768:Methylmethacrylates