title: Fabrication of porous zeolite/chitosan monoliths and their applications for drug release and metal ions adsorption.
abstract: Ordered porous zeolite/chitosan (Zel/Chi) monoliths were prepared by a unidirectional freeze-drying method, and their properties and structures were characterized by various instrumental methods. The metal ion adsorption and the drug release performance of the porous Zel/Chi monoliths were also studied. The release rate of cefalexin from drug-loaded Zel/Chi monoliths depended on the composition and porous structure of the monoliths. The metal ion adsorption capacity of the Zel/Chi monoliths was related to the concentration of the metal ions, the adsorption time and the Zel/Chi ratio. An experimentally maximum adsorption of 89 mg/g was achieved for Cu(2+) ions. The Zel/Chi monoliths with adsorbed Cu(2+) ions effectively catalyzed the reduction of 4-nitrophenol to 4-aminophenol and had good recyclability. They were easily recovered by simply removing them from the reaction system and rinsing them with water.
authors.affiliation: Huanhu Hospital, Tianjin 300060, PR China; Tianjin Cerebral Vascular and Neural Degenerative Disease Key Laboratory, Tianjin 300060, PR China.
authors.forename: Yongli
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Huanhu Hospital, Tianjin 300060, PR China; Tianjin Cerebral Vascular and Neural Degenerative Disease Key Laboratory, Tianjin 300060, PR China.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Yan
authors.affiliation: Huanhu Hospital, Tianjin 300060, PR China; Tianjin Cerebral Vascular and Neural Degenerative Disease Key Laboratory, Tianjin 300060, PR China. Electronic address: szhm618@163.com.
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Sun
authors.affiliation: School of Science, Tianjin University, Tianjin 300072, PR China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Pan
authors.affiliation: School of Medicine, Nankai University, Tianjin 300071, PR China. Electronic address: tjumixue@163.com.
authors.forename: Xue
authors.initials: X
authors.lastname: Mi
authors.affiliation: Huanhu Hospital, Tianjin 300060, PR China; Tianjin Cerebral Vascular and Neural Degenerative Disease Key Laboratory, Tianjin 300060, PR China.
authors.forename: Gang
authors.initials: G
authors.lastname: Zhao
authors.affiliation: School of Science, Tianjin University, Tianjin 300072, PR China. Electronic address: jianpingg@eyou.com.
authors.forename: Jianping
authors.initials: J
authors.lastname: Gao
mesh_terms: D000327:Adsorption; D000627:Aminophenols / Q000737:chemistry; D002384:Catalysis; D002482:Cellulose / Q000737:chemistry; D048271:Chitosan / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry*; D065546:Drug Liberation; D052578:Ionic Liquids / Q000737:chemistry; D019216:Metals, Heavy / Q000737:chemistry* / Q000302:isolation & purification; D009596:Nitrophenols / Q000737:chemistry; D010084:Oxidation-Reduction; D016062:Porosity; D062065:Wastewater / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000737:chemistry* / Q000302:isolation & purification; D017641:Zeolites / Q000737:chemistry*
chemical_list: D000627:Aminophenols; D002482:Cellulose; D048271:Chitosan; D004337:Drug Carriers; D052578:Ionic Liquids; D019216:Metals, Heavy; D009596:Nitrophenols; D062065:Wastewater; D014874:Water Pollutants, Chemical; D017641:Zeolites; C026729:4-aminophenol; C024836:4-nitrophenol
keywords: Adsorption; Chitosan; Drug releasing; Porous material; Zeolite