title: Hedgehog pathway mutations in T-cell acute lymphoblastic leukemia.
authors.affiliation: Center for the Biology of the Disease, VIB, Leuven Center for Human Genetics, KU Leuven.
authors.forename: Antonis
authors.initials: A
authors.lastname: Dagklis
authors.affiliation: Center for the Biology of the Disease, VIB, Leuven Center for Human Genetics, KU Leuven.
authors.forename: Daphnie
authors.initials: D
authors.lastname: Pauwels
authors.affiliation: Center for the Biology of the Disease, VIB, Leuven Center for Human Genetics, KU Leuven.
authors.forename: Idoya
authors.initials: I
authors.lastname: Lahortiga
authors.affiliation: Center for the Biology of the Disease, VIB, Leuven Center for Human Genetics, KU Leuven.
authors.forename: Ellen
authors.initials: E
authors.lastname: Geerdens
authors.affiliation: Department of Pathology UZ Leuven.
authors.forename: Emilie
authors.initials: E
authors.lastname: Bittoun
authors.affiliation: Laboratory Department of Hematology, AZ St Jan, Brugge.
authors.forename: Barbara
authors.initials: B
authors.lastname: Cauwelier
authors.affiliation: Department of Pathology UZ Leuven.
authors.forename: Thomas
authors.initials: T
authors.lastname: Tousseyn
authors.affiliation: Pediatric oncology, UZ Leuven.
authors.forename: Anne
authors.initials: A
authors.lastname: Uyttebroeck
authors.affiliation: Hematology Department, UZ Leuven, Belgium.
authors.forename: Johan
authors.initials: J
authors.lastname: Maertens
authors.affiliation: Hematology Department, UZ Leuven, Belgium.
authors.forename: Gregor
authors.initials: G
authors.lastname: Verhoef
authors.affiliation: Center for Human Genetics, KU Leuven.
authors.forename: Peter
authors.initials: P
authors.lastname: Vandenberghe
authors.affiliation: Center for the Biology of the Disease, VIB, Leuven Center for Human Genetics, KU Leuven Jan.cools@cme.vib-kuleuven.be.
authors.forename: Jan
authors.initials: J
authors.lastname: Cools
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D001483:Base Sequence; D002648:Child; D005260:Female; D015870:Gene Expression; D057809:HEK293 Cells; D006801:Humans; D051741:Kruppel-Like Transcription Factors / Q000235:genetics* / Q000276:immunology; D008297:Male; D008807:Mice, Inbred BALB C; D008969:Molecular Sequence Data; D009154:Mutation; D009419:Nerve Tissue Proteins / Q000235:genetics* / Q000276:immunology; D000072079:Patched Receptors; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000276:immunology / Q000473:pathology; D011956:Receptors, Cell Surface / Q000235:genetics* / Q000276:immunology; D043562:Receptors, G-Protein-Coupled / Q000235:genetics* / Q000276:immunology; D015398:Signal Transduction; D000072086:Smoothened Receptor; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology / Q000637:transplantation; D014157:Transcription Factors / Q000235:genetics* / Q000276:immunology; D014161:Transduction, Genetic; D000071676:Zinc Finger Protein GLI1; D000074290:Zinc Finger Protein Gli3
chemical_list: C400551:GLI1 protein, human; C065683:GLI3 protein, human; D051741:Kruppel-Like Transcription Factors; D009419:Nerve Tissue Proteins; D000072079:Patched Receptors; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; C491023:SMO protein, human; D000072086:Smoothened Receptor; D014157:Transcription Factors; D000071676:Zinc Finger Protein GLI1; D000074290:Zinc Finger Protein Gli3
keywords: Hedgehog pathway; leukemia; oncogene; signaling