title: Caregivers' quality of life in mild and moderate dementia.
abstract: OBJECTIVE
  To investigate quality of life (QoL) of caregivers of mild and moderate dementia and the aspects related to QoL.
  
  
  METHODS
  Cross-sectional assessment of dyads of people with dementia (PwD) and family caregivers (n=88).
  
  
  RESULTS
  Burden (p<0.05) and depressive symptoms (p<0.001) were related to caregivers' QoL in both stages of dementia. In mild dementia, caregivers' depressive symptoms (p<0.001) and PwD neuropsychiatric symptoms (p<0.001) were related to burden. PwD aberrant motor activity (p<0.001) and anxiety (p<0.001), and caregiver-reported QoL domains of friends (p<0.001) and mood (p<0.05) were related to depressive symptoms. In moderate dementia, self-reported QoL (p<0.01) and anxiety (p<0.01), and PwD anxiety (p<0.01) were related to burden. Caregivers' anxiety (p<0.001) and self-reported QoL (p<0.001) were related to depressive symptoms.
  
  
  CONCLUSIONS
  Burden and depressive symptoms were related to QoL of caregivers of mild and moderate dementia. However, they are driven by different factors according to dementia severity.
authors.affiliation: Centro para Doença de Alzheimer e Outros Transtornos Mentais da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Raquel Luiza
authors.initials: RL
authors.lastname: Santos
authors.affiliation: Centro para Doença de Alzheimer e Outros Transtornos Mentais da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Maria Fernanda Barroso de
authors.initials: MF
authors.lastname: Sousa
authors.affiliation: Departamento de Sociologia Política, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.
authors.forename: José Pedro
authors.initials: JP
authors.lastname: Simões-Neto
authors.affiliation: Centro para Doença de Alzheimer e Outros Transtornos Mentais da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Marcela Lima
authors.initials: ML
authors.lastname: Nogueira
authors.affiliation: Centro para Doença de Alzheimer e Outros Transtornos Mentais da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Tatiana T
authors.initials: TT
authors.lastname: Belfort
authors.affiliation: Centro para Doença de Alzheimer e Outros Transtornos Mentais da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Bianca
authors.initials: B
authors.lastname: Torres
authors.affiliation: Centro para Doença de Alzheimer e Outros Transtornos Mentais da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Rachel Dias Lopes da
authors.initials: RD
authors.lastname: Rosa
authors.affiliation: Centro para Doença de Alzheimer e Outros Transtornos Mentais da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Jerson
authors.initials: J
authors.lastname: Laks
authors.affiliation: Centro para Doença de Alzheimer e Outros Transtornos Mentais da Velhice, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Marcia Cristina Nascimento
authors.initials: MC
authors.lastname: Dourado
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000523:psychology; D017028:Caregivers / Q000523:psychology*; D003071:Cognition / Q000502:physiology; D003430:Cross-Sectional Studies; D003704:Dementia / Q000451:nursing*; D003863:Depression / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D057566:Self Report; D012720:Severity of Illness Index; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires