title: Dynamics of macular hole closure in gas-filled eyes within 24 h of surgery observed with swept source optical coherence tomography.
abstract: OBJECTIVE
  To investigate the dynamics of macular hole (MH) closure in gas-filled eyes starting 20 min after vitrectomy using swept source optical coherence tomography (SS-OCT).
  
  
  METHODS
  Twenty consecutive eyes with MH underwent vitrectomy with internal limiting membrane peeling and gas tamponade. SS-OCT imaging was performed approximately 20 min after the operation, and then once a day, until MH closure was confirmed. The correlation between the base, top and minimum hole diameters and the duration required for MH closure was investigated.
  
  
  RESULTS
  MH closure in gas-filled eyes was confirmed in 1 eye on day 0, 10 eyes on day 1, 2 eyes on day 2, and 3 eyes on day 3, at which times face-down posturing was discontinued without MH recurrence. SS-OCT revealed a distinct closure pattern within the first 24 h postoperatively. MHs closing by day 1 had a significantly smaller minimum diameter (312.5 ± 105.2 µm) than holes closing on day 2 or later (510.8 ± 153.5 µm; p = 0.019).
  
  
  CONCLUSIONS
  SS-OCT enables tomographic images of MH in gas-filled eyes immediately postoperatively, thus permitting early discontinuation of, or no necessity for, face-down positioning upon confirmation of MH closure.
authors.affiliation: Department of Ophthalmology, School of Medicine, Shinshu University, Matsumoto, Japan.
authors.forename: Wataru
authors.initials: W
authors.lastname: Kikushima
authors.forename: Akira
authors.initials: A
authors.lastname: Imai
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Toriyama
authors.forename: Takao
authors.initials: T
authors.lastname: Hirano
authors.forename: Toshinori
authors.initials: T
authors.lastname: Murata
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Ishibashi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001485:Basement Membrane / Q000601:surgery; D058450:Endotamponade; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016684:Prone Position; D011446:Prospective Studies; D012167:Retinal Perforations / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery*; D013459:Sulfur Hexafluoride / Q000008:administration & dosage*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy
chemical_list: D013459:Sulfur Hexafluoride