title: Coupling of carboxylic acids with internal alkynes by supported ruthenium catalysts: direct and selective syntheses of multi-substituted phthalide derivatives.
abstract: Supported ruthenium catalysts promote coupling of various kinds of aromatic carboxylic acids with internal alkynes, giving the corresponding multi-substituted phthalide derivatives in high yields. The supported Ru catalyst can be recycled at least five times with no loss of activity.
authors.affiliation: Department of Applied Chemistry, Graduate School of Urban Environmental Sciences, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0397, Japan. shishido-tetsuya@tmu.ac.jp.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Miura
authors.forename: Kentaro
authors.initials: K
authors.lastname: Tsutsui
authors.forename: Kenji
authors.initials: K
authors.lastname: Wada
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Shishido
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001572:Benzofurans / Q000138:chemical synthesis / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001572:Benzofurans; D002264:Carboxylic Acids; D012428:Ruthenium; C082022:phthalide