title: Diffusion Tensor Imaging in Radiation-Induced Myelopathy.
abstract: Radiation myelopathy (RM) is a rare complication of spinal cord irradiation. Diagnosis is based on the history of radiotherapy, laboratory tests, and magnetic resonance imaging of the spinal cord. The MRI findings may nevertheless be quite unspecific. In this paper, we describe the findings of diffusion tensor imaging in a case of the delayed form of RM. We observed areas of restricted diffusion within the spinal cord which probably corresponded to the ischemic changes. This would concur with the currently accepted pathogenetic theory concerning RM.
authors.affiliation: University Hospital Brno and Masaryk University, Department of Radiology, Central European Institute of Technology, Multimodal and Functional Imaging Laboratory.
authors.forename: Miloš
authors.initials: M
authors.lastname: Keřkovský
authors.affiliation: Masaryk Memorial Cancer Institute, Department of Radiation Oncology.
authors.forename: Jana
authors.initials: J
authors.lastname: Zitterbartová
authors.affiliation: University Hospital Brno and Masaryk University, Department of Internal Medicine, Hematology and Oncology.
authors.forename: Luděk
authors.initials: L
authors.lastname: Pour
authors.affiliation: University Hospital Brno and Masaryk University, Department of Radiology.
authors.forename: Andrea
authors.initials: A
authors.lastname: Šprláková-Puková
authors.affiliation: University Hospital Brno and Masaryk University, Department of Radiology.
authors.forename: Marek
authors.initials: M
authors.lastname: Mechl
mesh_terms: D003937:Diagnosis, Differential; D056324:Diffusion Tensor Imaging / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000209:etiology* / Q000473:pathology*; D020266:Radiotherapy, Conformal / Q000009:adverse effects*; D013118:Spinal Cord Diseases / Q000209:etiology* / Q000473:pathology*; D013125:Spinal Neoplasms / Q000532:radiotherapy; D016896:Treatment Outcome
keywords: Radiation myelopathy; diffusion tensor imaging; magnetic resonance imaging