title: [Case of azoospermia patient with a chromosomal abnormality considered a ring Y chromosome].
abstract: A 43-year-old man came to our clinic complaining of infertility and semen analysis showed azoospermia. Analysis of chromosomes showed a mosaic 45, XO/46, X, ＋mar1/46, X, ＋mar2 karyotype, and the marker chromosomes were considered to be two kinds of ring Y chromosomes. Y chromosome microdeletion analysis showed partial deletion of Azoospermic Factor (AZF) a, and complete deletion of AZFb and AZFc. The patient gave up having a child because these results indicated that no sperm would be collected even if Testicular Sperm Extraction (TESE) were performed.
authors.affiliation: The Department of Urology, Oguchi Higashi General Hospital; The Reproduction Medical Center of Urology, Yokohama City University Medical Center.
authors.forename: Shinnosuke
authors.initials: S
authors.lastname: Kuroda
authors.affiliation: The Reproduction Medical Center of Urology, Yokohama City University Medical Center.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Yumura
authors.affiliation: The Division of Genetic Counseling, Yokohama City University Hospital.
authors.forename: Haruka
authors.initials: H
authors.lastname: Hamanoue
authors.affiliation: The Department of Urology, Oguchi Higashi General Hospital; The Reproduction Medical Center of Urology, Yokohama City University Medical Center.
authors.forename: Kengo
authors.initials: K
authors.lastname: Yasuda
authors.affiliation: The Reproduction Medical Center of Urology, Yokohama City University Medical Center.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yamanaka
authors.affiliation: The Reproduction Medical Center of Urology, Yokohama City University Medical Center.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sanjo
authors.affiliation: The Reproduction Medical Center of Urology, Yokohama City University Medical Center.
authors.forename: Teppei
authors.initials: T
authors.lastname: Takeshima
authors.affiliation: The Reproduction Medical Center of Urology, Yokohama City University Medical Center.
authors.forename: Masataka
authors.initials: M
authors.lastname: Kobayashi
authors.affiliation: The Reproduction Medical Center of Urology, Yokohama City University Medical Center.
authors.forename: Yoshitake
authors.initials: Y
authors.lastname: Kato
authors.affiliation: The Reproduction Medical Center of Urology, Yokohama City University Medical Center.
authors.forename: Akira
authors.initials: A
authors.lastname: Iwasaki
authors.affiliation: The Reproduction Medical Center of Urology, Yokohama City University Medical Center.
authors.forename: Kazumi
authors.initials: K
authors.lastname: Noguchi
mesh_terms: D000328:Adult; D053713:Azoospermia / Q000235:genetics*; D002869:Chromosome Aberrations; D041322:Chromosomes, Human, Y / Q000235:genetics*; D017353:Gene Deletion; D006801:Humans; D008297:Male; D012303:Ring Chromosomes