title: Depressive symptoms associated with dabigatran: a case report.
abstract: Several studies have reported that depression and anxiety are very common in atrial fibrillation due to impaired quality of life. Dabigatran is an anti-aggregation agent used for the treatment of atrial fibrillation. In terms of drug interactions during treatment with dabigatran, patients suffering from minor depression are reported to be a population at risk. This report is about a 68-year-old man whose depressive symptoms were aggravated after taking dabigatran for atrial fibrillation. The case is discussed in terms of his aggravated depressive symptoms and the interaction between his prescription medications.
authors.affiliation: Department of Psychiatry, Neuropsychiatry Istanbul Hospital, Istanbul, Turkey.
authors.forename: Gul
authors.initials: G
authors.lastname: Eryilmaz
authors.affiliation: Department of Psychiatry, Kanuni SS Training and Research Hospital, Istanbul, Turkey.
authors.forename: Asli
authors.initials: A
authors.lastname: Enez Darcin
authors.affiliation: Department of Pharmacology, Maltepe University, Istanbul, Turkey.
authors.forename: Esra
authors.initials: E
authors.lastname: Saglam
authors.affiliation: Department of Psychiatry, Neuropsychiatry Istanbul Hospital, Istanbul, Turkey.
authors.forename: Isil
authors.initials: I
authors.lastname: Gogcegoz Gul
mesh_terms: D000991:Antithrombins / Q000009:adverse effects / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D015283:Citalopram / Q000627:therapeutic use*; D000069604:Dabigatran / Q000009:adverse effects / Q000627:therapeutic use*; D003863:Depression / Q000139:chemically induced / Q000188:drug therapy*; D004347:Drug Interactions; D006801:Humans; D008297:Male; D012893:Sleep Wake Disorders / Q000209:etiology / Q000523:psychology; D012934:Social Isolation / Q000523:psychology; D016896:Treatment Outcome
chemical_list: D000991:Antithrombins; D015283:Citalopram; D000069604:Dabigatran
keywords: antidepressants; dabigatran; depression; drug interaction