title: [Carcinoembryonic antigen as a marker of proliferative diseases of the lymphatic system in patients with chronic renal failure--case report].
abstract: In patients with CKD, anaemia mainly develops due to a decreased renal synthesis of erythropoietin. The anaemia, both normochromic and normocytic, becomes more severe as the glomerular filtration rate progressively decreases. Tumor markers are used to detect or monitor proliferative diseases. Carcinoembryonic antigen (CEA) is usually produced in the gastrointestinal tract, but its production is terminated before birth. The main application of this indicator is to monitor the treatment and the presence of metastases of colorectal cancer. We present a case of 86-year-old woman who was diagnosed with renal anaemia in stage 4 of chronic kidney disease (CKD), treated by periodic blood transfusions. This paper presents the difficulties in diagnosis and treatment of anemia with complex and different than renal origin anemia in patients with CKD. Patients require the detailed haematological diagnosis. Pointed out the usefulness of CEA in the diagnosis of lymphoma with co-existing renal failure. The use of erythropoietin in doses of nephrology allowed to avoid further blood transfusion.
authors.forename: Marzena
authors.initials: M
authors.lastname: Janas
authors.forename: Stanisław
authors.initials: S
authors.lastname: Niemczyk
authors.forename: Stanisław
authors.initials: S
authors.lastname: Mazur
mesh_terms: D000369:Aged, 80 and over; D000740:Anemia / Q000188:drug therapy / Q000209:etiology; D014408:Biomarkers, Tumor / Q000378:metabolism*; D001803:Blood Transfusion; D002272:Carcinoembryonic Antigen / Q000378:metabolism*; D000068256:Darbepoetin alfa; D004921:Erythropoietin / Q000031:analogs & derivatives / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D008223:Lymphoma / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D004921:Erythropoietin; D000068256:Darbepoetin alfa