title: Trans-cranial focused ultrasound without hair shaving: feasibility study in an ex vivo cadaver model.
abstract: In preparing a patient for a trans-cranial magnetic resonance (MR)-guided focused ultrasound procedure, current practice is to shave the patient's head on treatment day. Here we present an initial attempt to evaluate the feasibility of trans-cranial focused ultrasound in an unshaved, ex vivo human head model. A human skull filled with tissue-mimicking phantom and covered with a wig made of human hair was sonicated using 220- and 710-kHz head transducers to evaluate the feasibility of acoustic energy transfer. Heating at the focal point was measured by MR proton resonance shift thermometry. Results showed that the hair had a negligible effect on focal spot thermal rise at 220 kHz and a 17% drop in temperature elevation when using 710 kHz.
authors.affiliation: Focused Ultrasound Foundation, Charlottesville, VA 22903, USA.
authors.forename: Matthew Dc
authors.initials: MD
authors.lastname: Eames
authors.affiliation: Focused Ultrasound Foundation, Charlottesville, VA 22903, USA ; Department of Radiation Oncology, University of Virginia, Charlottesville, VA 22908, USA.
authors.forename: Arik
authors.initials: A
authors.lastname: Hananel
authors.affiliation: Focused Ultrasound Foundation, Charlottesville, VA 22903, USA ; Department of Neurosurgery, University of Virginia, Charlottesville, VA 22908, USA.
authors.forename: John W
authors.initials: JW
authors.lastname: Snell
authors.affiliation: Focused Ultrasound Foundation, Charlottesville, VA 22903, USA ; Department of Neurosurgery, University of Virginia, Charlottesville, VA 22908, USA.
authors.forename: Neal F
authors.initials: NF
authors.lastname: Kassell
authors.affiliation: Department of Radiation Oncology, University of Virginia, Charlottesville, VA 22908, USA ; Institut Langevin Ondes et Images, ESPCI ParisTech, CNRS UMR 7587, Inserm U979, Paris 75238, France.
authors.forename: Jean-Francois
authors.initials: JF
authors.lastname: Aubry
keywords: Brain; Hair; MR thermometry; tcMRgFUS