title: Imino-chitosan biopolymeric films. Obtaining, self-assembling, surface and antimicrobial properties.
abstract: The paper reports the preparation of twelve imino-chitosan biopolymer films by acid condensation of the amino groups of chitosan with various aldehydes, in aqueous medium, followed by slow water removal. FTIR spectroscopy has shown drastic conformation changes of chitosan macromolecular chains—from a stiff coil to a straight one, while wide angle X-ray diffraction evidenced a layered morphology of the biopolymer films. Contact angle and surface free energy determination indicated a higher biocompatibility of the new biopolymers as compared to the chitosan parent, while the microbiological screening demonstrated their self-defense properties against common and virulent pathogen agents. It was concluded that the reversibility of imine forming promotes the self-assembling of imino-chitosan biopolymer films into a lamellar morphology and, on the other hand, the slow release of the antimicrobial aldehyde in the microbiological culture. The obtained results demonstrate that chitosan polyamine is a challenging workbench to functional biodynamic materials.
authors.affiliation: "Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, 41A, Aleea Gr. Ghica Voda, Iasi, Romania. Electronic address: lmarin@icmpp.ro.
authors.forename: Luminita
authors.initials: L
authors.lastname: Marin
authors.affiliation: "Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, 41A, Aleea Gr. Ghica Voda, Iasi, Romania.
authors.forename: Daniela
authors.initials: D
authors.lastname: Ailincai
authors.affiliation: "Ion Ionescu de la Brad" University, Laboratory of Antimicrobial Chemotherapy, 8, Aleea Sadoveanu, Iasi, Romania.
authors.forename: Mihai
authors.initials: M
authors.lastname: Mares
authors.affiliation: "Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, 41A, Aleea Gr. Ghica Voda, Iasi, Romania.
authors.forename: Elena
authors.initials: E
authors.lastname: Paslaru
authors.affiliation: "Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, 41A, Aleea Gr. Ghica Voda, Iasi, Romania.
authors.forename: Mariana
authors.initials: M
authors.lastname: Cristea
authors.affiliation: "Al. I. Cuza" University, Faculty of Physics, 11 Carol I Bulv., Iasi R-700506, Romania.
authors.forename: Valentin
authors.initials: V
authors.lastname: Nica
authors.affiliation: "Petru Poni" Institute of Macromolecular Chemistry of Romanian Academy, 41A, Aleea Gr. Ghica Voda, Iasi, Romania; "Gheorghe Asachi" Technical University of Iasi, 73, Bd. Dimitrie Mangeron, Iasi, Romania.
authors.forename: Bogdan C
authors.initials: BC
authors.lastname: Simionescu
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D048271:Chitosan / Q000737:chemistry* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D055595:Mechanical Phenomena; D013211:Staphylococcus aureus / Q000187:drug effects; D013499:Surface Properties; D013816:Thermodynamics
chemical_list: D000890:Anti-Infective Agents; D048271:Chitosan
keywords: Antimicrobial; Chitosan; Film; Imine; Self-assembling; Trans-imination