title: [The pregnancy outcome in patients WITH β-thalassemia minor].
abstract: Thalassemia syndromes are heterogenic group hereditary hemoglobinopathies, provoking chronic hemolytic anemia. They affect approximately 100 million people, mostly in the Mediterranean (including Bulgaria), South-eastern Asia and Africa. Thalassemia syndromes are the second reason for hypochromic anemia and anemia in pregnancy after iron deficiency.
  
  
  OBJECTIVE
  To determine pregnancy outcome of women with β-thalassemia minor.
  
  
  METHODS
  It is an ambispective study in University Hospital of Obstetrics and Gynecology" Maichin dom", Sofia, for a year. Patients are divided in two groups regarding the presence of β-thalassemia minor. Preeclampsia, gestational diabetes mellitus, olygo- and polyhydramnion, preterm labor intrauterine growth retardation (IUGR), Cesarean section delivery are recorded in study groups.
  
  
  RESULTS
  Cases with β-thalassemia minor have significantly higher prevalence of oligohydramnion and Cesarean section delivery. There is no significant difference regarding Apgar score in 1st and 5th minute, IUGR, gestational diabetes mellitus and preeclampsia between two study groups.
  
  
  CONCLUSIONS
  β-Thalassemia minor does not significantly influence the pregnancy in negative way.
authors.forename: D
authors.initials: D
authors.lastname: Yordanova
authors.forename: A
authors.initials: A
authors.lastname: Nikolov
authors.forename: A
authors.initials: A
authors.lastname: Museva
authors.forename: V
authors.initials: V
authors.lastname: Karamiseva
mesh_terms: D000328:Adult; D001034:Apgar Score; D002031:Bulgaria / Q000453:epidemiology; D002585:Cesarean Section; D036861:Delivery, Obstetric; D016640:Diabetes, Gestational / Q000453:epidemiology; D005260:Female; D005317:Fetal Growth Retardation / Q000453:epidemiology; D006801:Humans; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000453:epidemiology; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000453:epidemiology*; D011256:Pregnancy Outcome / Q000453:epidemiology; D055815:Young Adult; D017086:beta-Thalassemia / Q000150:complications* / Q000453:epidemiology*