title: Focused ultrasound development and clinical adoption: 2013 update on the growth of the field.
abstract: The field of therapeutic focused ultrasound, which first emerged in the 1940s, has seen significant growth, particularly over the past decade. The eventual widespread clinical adoption of this non-invasive therapeutic modality require continued progress, in a multitude of activities including technical, pre-clinical, and clinical research, regulatory approval and reimbursement, manufacturer growth, and other commercial and public sector investments into the field, all within a multi-stakeholder environment. We present here a snapshot of the field of focused ultrasound and describe how it has progressed over the past several decades. It is assessed using metrics which include quantity and breadth of academic work (presentations, publications), funding trends, manufacturer presence in the field, number of treated patients, number of indications reaching first-in-human status, and quantity and breadth of clinical indications.
authors.affiliation: Focused Ultrasound Foundation, Charlottesville, VA 22903, USA.
authors.forename: Dasha
authors.initials: D
authors.lastname: Tyshlek
authors.affiliation: Department of Radiation Oncology, University of Virginia, Charlottesville, VA 22901, USA ; Institut Langevin, CNRS UMR 7587, ESPCI ParisTech, INSERM U979, Paris 75005, France.
authors.forename: Jean-Francois
authors.initials: JF
authors.lastname: Aubry
authors.affiliation: Division of Radiotherapy and Imaging, The Institute of Cancer Research, Royal Marsden Hospital, Sutton, Surrey, UK.
authors.forename: Gail
authors.initials: G
authors.lastname: Ter Haar
authors.affiliation: Focused Ultrasound Foundation, Charlottesville, VA 22903, USA ; Department of Radiation Oncology, University of Virginia, Charlottesville, VA 22901, USA.
authors.forename: Arik
authors.initials: A
authors.lastname: Hananel
authors.affiliation: Focused Ultrasound Foundation, Charlottesville, VA 22903, USA.
authors.forename: Jessica
authors.initials: J
authors.lastname: Foley
authors.affiliation: Focused Ultrasound Foundation, Charlottesville, VA 22903, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Eames
authors.affiliation: Focused Ultrasound Foundation, Charlottesville, VA 22903, USA ; Department of Neurosurgery, University of Virginia, Charlottesville, VA 22901, USA.
authors.forename: Neal
authors.initials: N
authors.lastname: Kassell
authors.affiliation: Focused Ultrasound Foundation, Charlottesville, VA 22903, USA.
authors.forename: Heather Huff
authors.initials: HH
authors.lastname: Simonin