title: [Comparison of angiography-guided and fractional flow reserve-guided management strategy of percutaneous coronary intervention for intermediate coronary lesions].
abstract: OBJECTIVE
  To compare the consistency of angiography-guided and fractional flow reserve (FFR)-guided management strategy for intermediate coronary lesions.
  
  
  METHODS
  The patients whose coronary intermediate lesions were assessed by measuring FFR from November 2012 to August 2014. The stenosis percentage and value of FFR during the procedure were collected. All the image data were collected and four experienced interventional cardiologists were invited to assess the target lesions and make a management strategy independently. The consistency of angiography-guided and fractional flow reserve-guided management strategy were analyzed.
  
  
  RESULTS
  In the study, 151 patients were included, of whom, 70.2% were male, the average age was (62.7±9.6) years, 169 vessels were assessed by measuring FFR, 1 being left main, 116 left anterior descending, 27 left circumflex branch, and 25 right coronary artery. There were some correlationship between the stenosis percentage judged by four interventional cardiologists and the stenosis percentage judged during the procedure (r=0.29-0.38, P<0.001), but the difference was significant. When 0.80 was used as FFR threshold value, the consistency rates of angiography-guided management strategy decision made by the four cardiologists with fractional flow reserve-guided management strategy were 72.78%, 71.60%, 75.15%, and 72.78%, respectively.
  
  
  CONCLUSIONS
  Angiography-guided management strategy decision is unreliable, FFR is recommended for management strategy decision for intermediate coronary lesions.
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Gong
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: H
authors.initials: H
authors.lastname: Hu
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: J
authors.initials: J
authors.lastname: Jiang
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: T
authors.initials: T
authors.lastname: Hong
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: J P
authors.initials: JP
authors.lastname: Li
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: M
authors.initials: M
authors.lastname: Chen
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Z P
authors.initials: ZP
authors.lastname: Liu
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Huo
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000473:pathology*; D005260:Female; D053805:Fractional Flow Reserve, Myocardial; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention; D016896:Treatment Outcome