title: [Changes in the functional state of the vascular endothelium in patients with hypertensive disease and heart valves calcification under influence of the lipid-lowering therapy].
abstract: In patients with essential hypertension (EH) and calcification of heart valves (HVC) were studied the dynamics of the functional state of the vasculai endothelium uinder the various options of the lipid-loweringtherapy. In patients with essential hypertension and HVC established the beneficial effect on vasoactive endothelial function in each version of lipid-lowering therapy. In larger dose of atorvastatin (40 mg/day) were observed better performance of the vasodilating endothelial function.
authors.forename: O V
authors.initials: OV
authors.lastname: Iuzvyshyna
mesh_terms: D000368:Aged; D000069059:Atorvastatin; D002114:Calcinosis / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000187:drug effects / Q000503:physiopathology*; D006349:Heart Valve Diseases / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D006538:Heptanoic Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D000960:Hypolipidemic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D011758:Pyrroles / Q000008:administration & dosage / Q000627:therapeutic use*; D014664:Vasodilation / Q000187:drug effects / Q000502:physiology
chemical_list: D006538:Heptanoic Acids; D000960:Hypolipidemic Agents; D011758:Pyrroles; D000069059:Atorvastatin