title: Case of immunoglobulin G4 (IgG4)-related disease diagnosed by transbronchial lung biopsy and endobronchial ultrasound-guided transbronchial needle aspiration.
abstract: A 62-year-old Japanese man was admitted to our hospital for evaluation of bilateral chest abnormal shadow.His lacrimal, submandibular and parotid glands had been swollen for several years. His serum immunoglobulin G4 (IgG4) level was >1,500 mg/dl, and chest computed tomography showed bilateral reticular opacities with enlarged mediastinal lymph nodes. Transbronchial lung biopsy and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) results suggested IgG4-related disease. This is the first report, to our knowledge, in the English literature showing EBUS-TBNA to be useful for diagnosing IgG4-related disease.
authors.affiliation: Department of Respiratory Medicine, School of Medicine University of Occupational and Environmental Health, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishimoto
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yatera
authors.forename: Ikuko
authors.initials: I
authors.lastname: Shimabukuro
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Matsuki
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Hanaka
authors.forename: Keishi
authors.initials: K
authors.lastname: Oda
authors.forename: Toshinori
authors.initials: T
authors.lastname: Kawanami
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mukae
mesh_terms: D015415:Biomarkers / Q000097:blood; D001706:Biopsy / Q000379:methods*; D001999:Bronchoscopy / Q000379:methods*; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000379:methods*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood* / Q000276:immunology*; D008168:Lung / Q000473:pathology*; D008171:Lung Diseases / Q000175:diagnosis* / Q000276:immunology* / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008482:Mediastinum; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D015415:Biomarkers; D007074:Immunoglobulin G