title: Effects of nasal septum perforation repair surgery on three-dimensional airflow: an evaluation using computational fluid dynamics.
abstract: The purpose of this research is to determine the cause of nasal perforation symptoms and to predict post-operative function after nasal perforation repair surgery. A realistic three-dimensional (3D) model of the nose with a septal perforation was reconstructed using a computed tomography (CT) scan from a patient with nasal septal defect. The numerical simulation was carried out using ANSYS CFX V13.0. Pre- and post-operative models were compared by their velocity, pressure gradient (PG), wall shear (WS), shear strain rate (SSR) and turbulence kinetic energy in three plains. In the post-operative state, the crossflows had disappeared, and stream lines bound to the olfactory cleft area had appeared. After surgery, almost all of high-shear stress areas were disappeared comparing pre-operative model. In conclusion, the effects of surgery to correct nasal septal perforation were evaluated using a three-dimensional airflow evaluation. Following the surgery, crossflows disappeared, and WS, PG and SSR rate were decreased. A high WS.PG and SSR were suspected as causes of nasal perforation symptoms.
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan. t-nomura@bc5.so-net.ne.jp.
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nomura
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
authors.forename: Munetaka
authors.initials: M
authors.lastname: Ushio
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kondo
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yamasoba
mesh_terms: D000403:Airway Resistance / Q000502:physiology*; D003198:Computer Simulation; D005260:Female; D006801:Humans; D057446:Hydrodynamics; D021621:Imaging, Three-Dimensional; D008875:Middle Aged; D061270:Nasal Septal Perforation / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D012119:Respiration; D013314:Stress, Mechanical; D014057:Tomography, X-Ray Computed
keywords: Airflow evaluation; Nasal septal perforation; Numerical simulation