title: Natural occurring 2-(2-phenylethyl) chromones, structure elucidation and biological activities.
abstract: 2-(2-Phenylethyl) chromone (PEC), an uncommon class of chromones, possesses a phenylethyl substituent at the C2 position. They have been isolated from a few plant species. They have promising biological activities such as neuro-protective, cytotoxic, acetylcholinesterase inhibitory, antibacterial and anti-inflammatory. This review focuses on the naturally occurring PEC derivatives, their sources, physical and spectral data, as well as biological activities.
authors.affiliation: a Department of Pharmacognosy and Pharmaceutical Chemistry , Faculty of Pharmacy, Taibah University, Al Madinah Al , Munawwarah 30078 , Kingdom of Saudi Arabia.
authors.forename: Sabrin R M
authors.initials: SR
authors.lastname: Ibrahim
authors.forename: Gamal A
authors.initials: GA
authors.lastname: Mohamed
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry; D000893:Anti-Inflammatory Agents / Q000737:chemistry; D002460:Cell Line; D045744:Cell Line, Tumor; D002800:Cholinesterase Inhibitors / Q000737:chemistry; D002867:Chromones / Q000737:chemistry*; D019662:Cucurbitaceae / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry*; D006801:Humans; D051379:Mice; D015394:Molecular Structure; D018696:Neuroprotective Agents / Q000737:chemistry; D029645:Thymelaeaceae / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D002800:Cholinesterase Inhibitors; D002867:Chromones; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D018696:Neuroprotective Agents; C062550:2-(2-phenylethyl)chromone
keywords: 2-(2-phenylethyl) chromones; biological activities; physical data; plant source; spectral data