title: Slow oscillations during sleep coordinate interregional communication in cortical networks.
abstract: Large-amplitude sleep slow oscillations group faster neuronal oscillations and are of functional relevance for memory performance. However, relatively little is known about the impact of slow oscillations on functionally coupled networks. Here, we provide a comprehensive view on how human slow oscillatory dynamics influence various measures of brain processing. We demonstrate that slow oscillations coordinate interregional cortical communication, as assessed by phase synchrony in the sleep spindle frequency range and cross-frequency coupling between spindle and beta activity. Furthermore, we show that the organizing role of slow oscillations is restricted to circumscribed topographical areas. These findings add importantly to our basic understanding of the orchestrating role of slow oscillations. In addition, they are of considerable relevance for accounts of sleep-dependent memory reprocessing and consolidation.
authors.affiliation: Department of Psychology, University of Amsterdam, 1018 XA Amsterdam, The Netherlands, and Amsterdam Brain and Cognition, University of Amsterdam, 1018 WS Amsterdam, The Netherlands roycox.roycox@gmail.com.
authors.forename: Roy
authors.initials: R
authors.lastname: Cox
authors.affiliation: Department of Psychology, University of Amsterdam, 1018 XA Amsterdam, The Netherlands, and Amsterdam Brain and Cognition, University of Amsterdam, 1018 WS Amsterdam, The Netherlands.
authors.forename: Joram
authors.initials: J
authors.lastname: van Driel
authors.affiliation: Department of Psychology, University of Amsterdam, 1018 XA Amsterdam, The Netherlands, and Amsterdam Brain and Cognition, University of Amsterdam, 1018 WS Amsterdam, The Netherlands.
authors.forename: Marieke
authors.initials: M
authors.lastname: de Boer
authors.affiliation: Department of Psychology, University of Amsterdam, 1018 XA Amsterdam, The Netherlands, and Amsterdam Brain and Cognition, University of Amsterdam, 1018 WS Amsterdam, The Netherlands.
authors.forename: Lucia M
authors.initials: LM
authors.lastname: Talamini
mesh_terms: D000293:Adolescent; D002540:Cerebral Cortex / Q000502:physiology*; D004569:Electroencephalography / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D009415:Nerve Net / Q000502:physiology*; D012890:Sleep / Q000502:physiology*; D055815:Young Adult
keywords: EEG; functional connectivity; memory; sleep spindles; slow oscillations