title: Personalized medicine in Type 2 Diabetes.
abstract: Type 2 diabetes (T2D) is a global public health concern, its prevalence in Asia, especially Taiwan, rising every year. The risk of developing T2D and diabetes complications is not only controlled by environmental but also by genetic factors. Genetic association studies have shown polymorphisms at specific loci may help identify individuals at greatest risk and response to oral antidiabetic drugs. This review probes effect of genetic profiling on T2D and its complications, using our study population as examples. Also, pharmacogenetics and pharmacogenomics of oral anitdiabetic drug will be explored.
authors.affiliation: Center for Personalized Medicine, China Medical University Hospital, Taichung, Taiwan ; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan.
authors.forename: Wen-Ling
authors.initials: WL
authors.lastname: Liao
authors.affiliation: Department of Medical Research and Medical Genetics, China Medical University Hospital Taichung, Taichung, Taiwan ; School of Chinese Medicine, China Medical University, Taichung, Taiwan ; Department of Pediatrics, China Medical University Hospital, Taichung, Taiwan ; Department of Health and Nutrition Biotechnology, Asia University, Taichung, Taiwan ; Department of Medical Genetics, Pediatrics and Medical Research, China Medical University Hospital, No.2 Yuh-Der Road, 404 Taichung, Taiwan.
authors.forename: Fuu-Jen
authors.initials: FJ
authors.lastname: Tsai
keywords: Diabetes; Genetic; Pharmacogenetics