title: I've been taking methotrexate for my rheumatoid arthritis (RA) for several years, but it doesn't seem to be helping my symptoms. My doctor suggested adding a biologic response modifier (BRM) drug, such as etanercept (Enbrel) or adalimumab (Humira) to my treatment plan, but I've heard that BRMs can increase cancer risk.
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D000068800:Etanercept; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects / Q000627:therapeutic use*; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use*; D009369:Neoplasms / Q000139:chemically induced; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use*
chemical_list: D018501:Antirheumatic Agents; D007074:Immunoglobulin G; D018124:Receptors, Tumor Necrosis Factor; D000068800:Etanercept; D008727:Methotrexate