title: The predictive value of the Boston Acute Stroke Imaging Scale (BASIS) in acute ischemic stroke patients among Chinese population.
abstract: OBJECTIVE
  Evaluate the predictive value of Boston Acute Stroke Imaging Scale (BASIS) in acute ischemic stroke in Chinese population.
  
  
  METHODS
  This was a retrospective study. 566 patients of acute ischemic stroke were classified as having a major stroke or minor stroke based on BASIS. We compared short-term outcome (death, occurrence of complications, admission to intensive care unit [ICU] or neurological intensive care unit [NICU]), long-term outcome (death, recurrence of stroke, myocardial infarction, modified Rankin scale) and economic index including in-hospital cost and length of hospitalization. Continuous variables were compared by using the Student t test or Kruskal-Wallis test. Categorical variables were tested with the Chi square test. Cox regression analysis was applied to identify whether BASIS was the independent predictive variable of death.
  
  
  RESULTS
  During hospitalization, 9 patients (4.6%) died in major stroke group while no patients died in minor stroke group (p < 0.001), 12 patients in the major stroke group and 5 patients in minor stroke group were admitted to ICU/NICU (p = 0.001). There were more complications (cerebral hernia, pneumonia, urinary tract infection) in major stroke group than minor stroke group (p<0.05). Meanwhile, the average cost of hospitalization in major stroke group was 3,100 US$ and 1,740 US$ in minor stroke group (p<0.001); the average length of stay in major and minor stroke group was 21.3 days and 17.3 days respectively (p<0.001). Results of the follow-up showed that 52 patients (26.7%) died in major stroke group while 56 patients (15.1%) died in minor stroke group (P<0.001). 62.2% of the patients in major stroke group and 80.4% of the patients in minor stroke group were able to live independently (P = 0.002). The survival analysis showed that patients with major stroke had 80% higher of risk of death than patients with minor stroke even after adjusting traditional atherosclerotic factors and NIHSS at baseline (HR = 1.8, 95% CI: 1.1-3.1).
  
  
  CONCLUSIONS
  BASIS can predict in-hospital mortality, occurrence of complication, length of stay and hospitalization cost of the acute ischemic stroke patients and can also estimate the long term outcome (death and the dependency). BASIS could and should be used as a dichotomous stroke classification system in the daily practice.
authors.affiliation: Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China. cassiesandra@163.com
authors.forename: Yuanqi
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: National Clinical Research Center of Kidney Disease, State Key Laboratory of Organ Failure Research, Southern Medical University, Guangzhou, China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhao
authors.affiliation: Department of Neurology, JiangmenWuyi Traditional Chinese Medicine Hospital, Jiangmen, Guangdong, China.
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Neurology, Yue Bei people's Hospital, Shaoguan, Guangdong, China.
authors.forename: Xiancong
authors.initials: X
authors.lastname: Ma
authors.affiliation: Department of Internal medicine, Meizhou Municipal Hospital of traditional Chinese Medicine, Meizhou, Guangdong, China.
authors.forename: Qinghao
authors.initials: Q
authors.lastname: Zheng
authors.affiliation: Department of Neurology, Kang Mei Hospital, Jieyang, Guangdong, China.
authors.forename: Xiaosheng
authors.initials: X
authors.lastname: Chen
authors.affiliation: Department of Chinese Medicine, Kwong Wah Hospital-The Chinese University of Hong Kong Chinese Medicine Clinical Research and Services Center, Hong Kong, China.
authors.forename: Yinwing
authors.initials: Y
authors.lastname: Lin
authors.affiliation: Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China.
authors.forename: Yefeng
authors.initials: Y
authors.lastname: Cai
mesh_terms: D000368:Aged; D044466:Asian People; D002545:Brain Ischemia / Q000150:complications*; D002681:China; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012720:Severity of Illness Index; D020521:Stroke / Q000150:complications* / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D014057:Tomography, X-Ray Computed