title: Leucine-rich glioma-inactivated protein 1 antibody encephalitis: A case report.
abstract: OBJECTIVE
  To describe a case of leucine-rich glioma-inactivated protein 1 (LGI1) antibody-associated encephalitis.
  
  
  METHODS
  The clinical and ancillary data and brain MRIs were gathered retrospectively by chart review. Relevant literature on similar cases was also reviewed.
  
  
  RESULTS
  The diagnosis of LGI1 antibody-associated autoimmune encephalitis was based on the typical clinical presentation of seizures, psychiatric symptoms, and memory loss as well as negative diagnostic testing for cancer; the diagnosis was confirmed by positive LGI1 antibody. The patient responded favorably to treatment with IV immunoglobulin and continues to do well.
  
  
  CONCLUSIONS
  LGI1 antibody-associated encephalitis has increasingly been recognized as a primary autoimmune disorder with good prognosis and response to treatment.
authors.affiliation: Departments of Neurology (Y.M., N.G.) and Radiology (D.T.), University of Massachusetts Medical School, Worcester, MA.
authors.forename: Yunis
authors.initials: Y
authors.lastname: Mayasi
authors.affiliation: Departments of Neurology (Y.M., N.G.) and Radiology (D.T.), University of Massachusetts Medical School, Worcester, MA.
authors.forename: Deepak
authors.initials: D
authors.lastname: Takhtani
authors.affiliation: Departments of Neurology (Y.M., N.G.) and Radiology (D.T.), University of Massachusetts Medical School, Worcester, MA.
authors.forename: Neeta
authors.initials: N
authors.lastname: Garg