title: Dead space during one-lung ventilation.
abstract: OBJECTIVE
  Describe the importance of monitoring dead space during thoracic surgery, specifically during one-lung ventilation.
  
  
  RESULTS
  The concept of dead space has gained renewed interest among anesthesiologists ever since breath-by-breath measurement by volumetric capnography became available. Monitoring dead space during thoracic surgery assesses the ventilatory deficiencies related to increases in instrumental, airway and/or alveolar dead space, when ventilating patients with positive pressure and double-lumen tubes. Another interesting use of such monitoring is to detect ventilator-induced lung injury due to tidal overdistension. This type of injury threatens the fragile lungs especially during one-lung ventilation and can clinically be recognized as an increase in airway and alveolar dead space above normal values. To date, lung protective ventilation is based on the use of low tidal volumes and airway pressures to decrease overdistension. It has been shown to reduce the incidence of postoperative pulmonary complications after thoracic surgeries. However, such a ventilatory strategy impairs ventilation and induces hypercapnia due to increases in dead space. Therefore, continuous assessment of dead space is helpful in guiding ventilation and avoiding overdistension while maintaining the elimination of CO(2) during thoracic surgery sufficiently high.
  
  
  CONCLUSIONS
  Monitoring dead space helps anesthesiologists monitor the status of the lung and find appropriate ventilatory settings during thoracic surgeries.
authors.affiliation: aDepartment of Anesthesiology, Hospital Privado de Comunidad, Mar del Plata, Argentina bSwisstom AG, Landquart, Switzerland cDepartment of Anesthesiology and Critical Care, Hedenstierna Laboratory, Uppsala University Hospital dDepartment of Surgical Sciences, Uppsala University, Uppsala, Sweden eCIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.
authors.forename: Gerardo
authors.initials: G
authors.lastname: Tusman
authors.forename: Stephan H
authors.initials: SH
authors.lastname: Böhm
authors.forename: Fernando
authors.initials: F
authors.lastname: Suarez-Sipmann
mesh_terms: D006801:Humans; D016343:Monitoring, Intraoperative; D061810:One-Lung Ventilation / Q000379:methods*; D012121:Respiration, Artificial; D012126:Respiratory Dead Space / Q000502:physiology*; D019616:Thoracic Surgical Procedures / Q000009:adverse effects / Q000379:methods*