title: Mirabel: an integrated project for risk and cost/benefit analysis of peanut allergy.
abstract: Food allergy is a major public health issue. However, no regulatory measures exist when allergens are present at trace levels and the different risk components are poorly described. Thus, knowledge on exposure components such as the allergens present in foods and the consumption behaviour of allergic consumers and models to estimate the related risk need to be enriched. Mirabel proposes for the first time studying each risk component using an integrated approach in order to improve the quality of life of the allergic population. Field surveys were conducted in order to fill in the current gaps in unintentional allergen traces in food, allergic consumers' food behaviour, threshold doses of allergic reaction, allergy symptoms and severity. The aim is also to propose methodological and operational tools to quantify allergic risk, to test management scenarios and to produce a cost/benefit analysis. Medical data on the peanut allergies of 785 patients were collected in the MIRABEL survey and 443 patients answered the food consumption questionnaire. The population surveyed was mostly paediatric - 86% were children under 16 years of age, with a high percentage of males (60%). This project will generate tangible results on peanut allergen exposure and risk which could be used in future risk assessment work and particularly to provide science-based guidance to set up concentration limits for peanut traces on packages.
authors.affiliation: Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health Safety (ANSES), Maisons-Alfort, France. Electronic address: amelie.crepet@anses.fr.
authors.forename: A
authors.initials: A
authors.lastname: Crépet
authors.affiliation: Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health Safety (ANSES), Maisons-Alfort, France.
authors.forename: A
authors.initials: A
authors.lastname: Papadopoulos
authors.affiliation: Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health Safety (ANSES), Maisons-Alfort, France.
authors.forename: C F
authors.initials: CF
authors.lastname: Elegbede
authors.affiliation: Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health Safety (ANSES), Maisons-Alfort, France.
authors.forename: S
authors.initials: S
authors.lastname: Ait-Dahmane
authors.affiliation: Risk Assessment Department (DER), French Agency for Food, Environmental and Occupational Health Safety (ANSES), Maisons-Alfort, France.
authors.forename: C
authors.initials: C
authors.lastname: Loynet
authors.affiliation: Public Economy Unit, National Institute of Agronomic Research (INRA), Thiverval-Grignon, France.
authors.forename: G
authors.initials: G
authors.lastname: Millet
authors.affiliation: Clinic Saint-Luc, Bouge, Namur, Belgium.
authors.forename: X
authors.initials: X
authors.lastname: Van Der Brempt
authors.affiliation: Liège University, Liège, Belgium.
authors.forename: O
authors.initials: O
authors.lastname: Bruyère
authors.affiliation: Public Economy Unit, National Institute of Agronomic Research (INRA), Thiverval-Grignon, France.
authors.forename: S
authors.initials: S
authors.lastname: Marette
authors.affiliation: Allergyvigilance Network, Vandoeuvre les Nancy, France; Faculty of Medicine, Nancy, France.
authors.forename: D A
authors.initials: DA
authors.lastname: Moneret-Vautrin
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003362:Cost-Benefit Analysis / Q000379:methods*; D015930:Diet Records; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D021183:Peanut Hypersensitivity / Q000175:diagnosis / Q000191:economics* / Q000453:epidemiology*; D012307:Risk Factors; D055815:Young Adult
keywords: Allergic consumer behaviors; Allergy; Food labelling; Peanut allergen; Risk assessment; Risk management