title: [An analysis of clinical factors in patients with hepatocellular carcinoma after transcatheter arterial chemoembolization complicated with diabetes].
abstract: OBJECTIVE
  To investigate related clinical factors of hepatocellular carcinoma (HCC) patients received transcatheter arterial chemoembolization (TACE) complicated with hepatogenous diabetes (HD).
  
  
  METHODS
  Forty eight cases of HCC line after TACE combined HD patients as the case group, and another forty eight cases of HCC line after TACE without HD patients as control group. A case-control study was retrospectively analyzed among two groups. A logistic regression modelwas established.
  
  
  RESULTS
  Multivariates analysis showed that family history of diabetes (OR = 3.464, 95% CI 1.100-10.909, P = 0.034), HBV DNA >1 × 10⁵ IU/ml (OR = 5.420, 95% CI 1.235-23.792, P = 0.025), liver function Child-Pugh C (OR = 7.653, 95% CI 1.385-42.301, P = 0.020), major larger tumors >10 cm (OR = 5.347, 95% CI 1.499-19.067, P = 0.010), the initial embolism area > 70% (OR = 9.031, 95% CI 1.782-48.537, P = 0.008), TACE > 3 times (OR = 3.726, 95% CI 1.151-12.065, P = 0.028) were independent risk factors of HD in patients with HCC after TACE.
  
  
  CONCLUSIONS
  Family history of diabetes, HBV DNA > 1 × 10⁵ IU/ml, Child-Pugh C, major tumors size > 10 cm, the initial embolism area > 70%, TACE > 3 times were independent risk factors of HD in HCC patients after TACE. As for factors to these patients, the blood glucose was monitored promptly in order to early diagnosis and treatment.
authors.affiliation: Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Wenzhe
authors.initials: W
authors.lastname: Fan
authors.affiliation: Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Yingqiang
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Xuehua
authors.initials: X
authors.lastname: Yao
authors.affiliation: Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
authors.forename: Jianyong
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Interventional Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China. Email: jpli3s@medmail.com.cn.
authors.forename: Jiaping
authors.initials: J
authors.lastname: Li
mesh_terms: D001158:Arteries; D006528:Carcinoma, Hepatocellular; D016022:Case-Control Studies; D016461:Chemoembolization, Therapeutic; D003920:Diabetes Mellitus; D006801:Humans; D008113:Liver Neoplasms; D012189:Retrospective Studies