title: Crohns disease with central nervous system vasculitis causing subarachnoid hemorrhage due to aneurysm and cerebral ischemic stroke.
abstract: Cerebral vasculitis secondary to Crohn's disease (CD) seems to be a very rare phenomenon. We report a 39-year-old male who presented with headache, vomiting, and left-sided weakness in the known case of CD. Cross-sectional imaging (computed tomography and magnetic resonance imaging,) showed right gangliocapsular acute infarct with supraclinoid cistern subarachnoid hemorrhage (SAH). Cerebral digital substraction angiography (DSA) showed dilatation and narrowing of right distal internal carotid artery (ICA). Left ICA was chronically occluded. His inflammatory markers were significantly raised. Imaging features are suggestive of cerebral vasculitis. Arterial and venous infarcts due to thrombosis are known in CD. Our case presented with acute subarachnoid hemorrhage in supraclinoid cistern due to rupture of tiny aneurysm of perforator arteries causing SAH and infarction in right basal ganglia. Patient was treated conservatively with immunosuppression along with medical management of SAH.
authors.affiliation: Department of Intervention Radiology, Bombay Hospital and Medical Research Centre, Mumbai, India.
authors.forename: Shaileshkumar S
authors.initials: SS
authors.lastname: Garge
authors.affiliation: Department of Intervention Radiology, Bombay Hospital and Medical Research Centre, Mumbai, India.
authors.forename: Pooja D
authors.initials: PD
authors.lastname: Vyas
authors.affiliation: Department of Intervention Radiology, Bombay Hospital and Medical Research Centre, Mumbai, India.
authors.forename: Pranav D
authors.initials: PD
authors.lastname: Modi
authors.affiliation: Department of Intervention Radiology, Bombay Hospital and Medical Research Centre, Mumbai, India.
authors.forename: Sharad
authors.initials: S
authors.lastname: Ghatge
keywords: Aneurysm; Crohn's disease; cerebral ischemia; extra-intestinal manifestations; subarachnoid hemorrhage; vasculitis