title: Focal autoimmune pancreatitis and chronic sclerosing sialadenitis mimicking pancreatic cancer and neck metastasis.
abstract: Type 1 autoimmune pancreatitis (AIP) or chronic sclerosing sialadenitis (Küttner's tumour) is an uncommon disorder that has recently been confirmed as an IgG4-related disease. Here, we describe a rare case of a 53-year-old male patient who primarily presented with pancreatic body mass, left neck mass and several lumps in his lower lip mimicking pancreatic cancer (PC) and neck metastasis. The patient underwent pancreatic body mass and labial gland lumps resection as well as an ultrasound-guided biopsy of the left neck mass. He was diagnosed with IgG4-related focal type of AIP (f-AIP) and Küttner's tumour by immunohistochemistry. The patient responded well to corticosteroid therapy and remains healthy with no signs of recurrence at one year follow-up. The differentiation of f-AIP from PC is very important to avoid unnecessary pancreatic resection.
authors.affiliation: Li Sun, Qiang Zhou, Su Yan, Ming Xiu, Rong-Li Piao, Yan-Hang Gao, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, First Hospital, Jilin University, Changchun 130021, Jilin Province, China.
authors.forename: Li
authors.initials: L
authors.lastname: Sun
authors.affiliation: Li Sun, Qiang Zhou, Su Yan, Ming Xiu, Rong-Li Piao, Yan-Hang Gao, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, First Hospital, Jilin University, Changchun 130021, Jilin Province, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhou
authors.affiliation: Li Sun, Qiang Zhou, Su Yan, Ming Xiu, Rong-Li Piao, Yan-Hang Gao, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, First Hospital, Jilin University, Changchun 130021, Jilin Province, China.
authors.forename: David R
authors.initials: DR
authors.lastname: Brigstock
authors.affiliation: Li Sun, Qiang Zhou, Su Yan, Ming Xiu, Rong-Li Piao, Yan-Hang Gao, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, First Hospital, Jilin University, Changchun 130021, Jilin Province, China.
authors.forename: Su
authors.initials: S
authors.lastname: Yan
authors.affiliation: Li Sun, Qiang Zhou, Su Yan, Ming Xiu, Rong-Li Piao, Yan-Hang Gao, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, First Hospital, Jilin University, Changchun 130021, Jilin Province, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Xiu
authors.affiliation: Li Sun, Qiang Zhou, Su Yan, Ming Xiu, Rong-Li Piao, Yan-Hang Gao, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, First Hospital, Jilin University, Changchun 130021, Jilin Province, China.
authors.forename: Rong-Li
authors.initials: RL
authors.lastname: Piao
authors.affiliation: Li Sun, Qiang Zhou, Su Yan, Ming Xiu, Rong-Li Piao, Yan-Hang Gao, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, First Hospital, Jilin University, Changchun 130021, Jilin Province, China.
authors.forename: Yan-Hang
authors.initials: YH
authors.lastname: Gao
authors.affiliation: Li Sun, Qiang Zhou, Su Yan, Ming Xiu, Rong-Li Piao, Yan-Hang Gao, Run-Ping Gao, Department of Hepatic-Biliary-Pancreatic Medicine, First Hospital, Jilin University, Changchun 130021, Jilin Province, China.
authors.forename: Run-Ping
authors.initials: RP
authors.lastname: Gao
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D003937:Diagnosis, Differential; D006258:Head and Neck Neoplasms / Q000556:secondary*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000473:pathology*; D010195:Pancreatitis / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D010950:Plasma Cells / Q000276:immunology; D011237:Predictive Value of Tests; D012598:Sclerosis / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D012793:Sialadenitis / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D013364:Submandibular Gland Diseases / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D015415:Biomarkers; D007074:Immunoglobulin G
keywords: Autoimmune pancreatitis; IgG4-related disease; IgG4-related focal type of AIP; Küttner’s tumour; Pancreatic cancer