title: Acquired superoxide-scavenging ability of ceria nanoparticles.
abstract: Ceria nanoparticles (nanoceria) are well known as a superoxide scavenger. However, inherent superoxide-scavenging ability has only been found in the nanoceria with sizes of less than 5 nm and with very limited shape diversity. Reported herein is a strategy to significantly improve the superoxide-scavenging activity of nanoceria sized at greater than 5 nm. The nanoceria with sizes of greater than 5 nm, with different shapes, and with a negligible Ce(3+)/Ce(4+) ratio can acquire remarkable superoxide-scavenging abilities through electron transfer. This method will make it possible to develop nanoceria-based superoxide-scavengers with long-acting activity and tailorable characteristics.
authors.affiliation: Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Key Laboratory of Nuclear Radiation and Nuclear Energy Technology, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100049 (China).
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Li
authors.forename: Xiao
authors.initials: X
authors.lastname: He
authors.forename: Jun-Jie
authors.initials: JJ
authors.lastname: Yin
authors.forename: Yuhui
authors.initials: Y
authors.lastname: Ma
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
authors.forename: Jingyuan
authors.initials: J
authors.lastname: Li
authors.forename: Yayun
authors.initials: Y
authors.lastname: Ding
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Zhifang
authors.initials: Z
authors.lastname: Chai
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D002563:Cerium / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D013481:Superoxides / Q000737:chemistry*
chemical_list: D016166:Free Radical Scavengers; D013481:Superoxides; D002563:Cerium
keywords: cerium; electron transfer; nanoparticles; oxides; surface chemistry