title: Zwitterionic glycosyl modified polyethersulfone membranes with enhanced anti-fouling property and blood compatibility.
abstract: In this study, novel zwitterionic glycosyl modified polyethersulfone (PES) ultrafiltration membranes were prepared via in-situ cross-linking polymerization coupled with phase inversion technique, and the following reactions. The membranes were characterized by Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), (1)HNMR spectrum, and static water contact angles (WCAs) measurements. The modified membranes showed excellent anti-fouling property, and the flux recovery ratio could reach almost 100%. Meanwhile, the blood compatibility of the membranes was measured by protein adsorption, platelet adhesion, activated partial thromboplastin time (APTT), and thrombin time (TT). The results implied that the zwitterionic glycosyl modified PES membranes had good anti-fouling property and blood compatibility.
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Xie
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China.
authors.forename: Shuang-Si
authors.initials: SS
authors.lastname: Li
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Jiang
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China. Electronic address: xita198906@163.com.
authors.forename: Tao
authors.initials: T
authors.lastname: Xiang
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.affiliation: College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China; National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China. Electronic address: zhaochsh70@163.com.
authors.forename: Chang-Sheng
authors.initials: CS
authors.lastname: Zhao
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D057219:Biofouling / Q000517:prevention & control*; D002417:Cattle; D006648:Histocompatibility; D057927:Hydrophobic and Hydrophilic Interactions; D008567:Membranes, Artificial; D010973:Platelet Adhesiveness; D011108:Polymers / Q000737:chemistry* / Q000494:pharmacology; D012710:Serum Albumin, Bovine / Q000737:chemistry; D013450:Sulfones / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011108:Polymers; D013450:Sulfones; C022840:polyether sulfone; D012710:Serum Albumin, Bovine
keywords: Anti-fouling property; Blood compatibility; In-situ cross-linking polymerization; Ultrafiltration membrane; Zwitterionic glycosyl