title: Effect of periodontal treatment on adipokines in type 2 diabetes.
abstract: The association between adipokines and inflammatory periodontal diseases has been studied over the last two decades. This review was intended to explore the observation that periodontal therapy may lead to an improvement of adipokines in diabetic patients. In summary, substantial evidence suggests that diabetes is associated with increased prevalence, extent and severity of periodontitis. Numerous mechanisms have been elucidated to explain the impact of diabetes on the periodontium. However, current knowledge concerning the role of major adipokines indicates only some of their associations with the pathogenesis of periodontitis in type 2 diabetes. Conversely, treatment of periodontal disease and reduction of oral inflammation may have positive effects on the diabetic condition, although evidence for this remains somewhat equivocal.
authors.affiliation: Hiroshi Ogawa, Teerasak Damrongrungruang, Sayaka Hori, Kaname Nouno, Kumiko Minagawa, Misuzu Sato, Hideo Miyazaki, Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8514, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ogawa
authors.affiliation: Hiroshi Ogawa, Teerasak Damrongrungruang, Sayaka Hori, Kaname Nouno, Kumiko Minagawa, Misuzu Sato, Hideo Miyazaki, Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8514, Japan.
authors.forename: Teerasak
authors.initials: T
authors.lastname: Damrongrungruang
authors.affiliation: Hiroshi Ogawa, Teerasak Damrongrungruang, Sayaka Hori, Kaname Nouno, Kumiko Minagawa, Misuzu Sato, Hideo Miyazaki, Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8514, Japan.
authors.forename: Sayaka
authors.initials: S
authors.lastname: Hori
authors.affiliation: Hiroshi Ogawa, Teerasak Damrongrungruang, Sayaka Hori, Kaname Nouno, Kumiko Minagawa, Misuzu Sato, Hideo Miyazaki, Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8514, Japan.
authors.forename: Kaname
authors.initials: K
authors.lastname: Nouno
authors.affiliation: Hiroshi Ogawa, Teerasak Damrongrungruang, Sayaka Hori, Kaname Nouno, Kumiko Minagawa, Misuzu Sato, Hideo Miyazaki, Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8514, Japan.
authors.forename: Kumiko
authors.initials: K
authors.lastname: Minagawa
authors.affiliation: Hiroshi Ogawa, Teerasak Damrongrungruang, Sayaka Hori, Kaname Nouno, Kumiko Minagawa, Misuzu Sato, Hideo Miyazaki, Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8514, Japan.
authors.forename: Misuzu
authors.initials: M
authors.lastname: Sato
authors.affiliation: Hiroshi Ogawa, Teerasak Damrongrungruang, Sayaka Hori, Kaname Nouno, Kumiko Minagawa, Misuzu Sato, Hideo Miyazaki, Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 951-8514, Japan.
authors.forename: Hideo
authors.initials: H
authors.lastname: Miyazaki
keywords: Adipokines; Diabetes; Periodontal disease; Periodontal therapy