title: Transcriptomic resources for environmental risk assessment: a case study in the Venice lagoon.
abstract: The development of new resources to evaluate the environmental status is becoming increasingly important representing a key challenge for ocean and coastal management. Recently, the employment of transcriptomics in aquatic toxicology has led to increasing initiatives proposing to integrate eco-toxicogenomics in the evaluation of marine ecosystem health. However, several technical issues need to be addressed before introducing genomics as a reliable tool in regulatory ecotoxicology. The Venice lagoon constitutes an excellent case, in which the assessment of environmental risks derived from the nearby industrial activities represents a crucial task. In this context, the potential role of genomics to assist environmental monitoring was investigated through the definition of reliable gene expression markers associated to chemical contamination in Manila clams, and their subsequent employment for the classification of Venice lagoon areas. Overall, the present study addresses key issues to evaluate the future outlooks of genomics in the environmental monitoring and risk assessment.
authors.affiliation: Department of Comparative Biomedicine and Food Science, University of Padova, Viale dell'Università 16, 35020 Legnaro, PD, Italy. Electronic address: massimo.milan@unipd.it.
authors.forename: M
authors.initials: M
authors.lastname: Milan
authors.affiliation: Department of Comparative Biomedicine and Food Science, University of Padova, Viale dell'Università 16, 35020 Legnaro, PD, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Pauletto
authors.affiliation: Azienda ULSS n. 14 Chioggia, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Boffo
authors.affiliation: Thetis S.P.A. - Magistrato alle Acque, Laboratorio Centro Studi Microinquinanti Organici (C.S.M.O.), Via Asconio Pediano, 9, 35127 Padova, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Carrer
authors.affiliation: Ufficio Tecnico per l'Antinquinamento, Magistrato alle Acque di Venezia, San Polo 737, Riva del Vin, 30125 Venezia, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Sorrentino
authors.affiliation: Ufficio Tecnico per l'Antinquinamento, Magistrato alle Acque di Venezia, San Polo 737, Riva del Vin, 30125 Venezia, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Ferrari
authors.affiliation: G3 Industriale, Via Milano 18, 30020 Marcon, VE, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Pavan
authors.affiliation: Department of Comparative Biomedicine and Food Science, University of Padova, Viale dell'Università 16, 35020 Legnaro, PD, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Patarnello
authors.affiliation: Department of Comparative Biomedicine and Food Science, University of Padova, Viale dell'Università 16, 35020 Legnaro, PD, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Bargelloni
mesh_terms: D000818:Animals; D049872:Bivalvia / Q000235:genetics / Q000378:metabolism; D017753:Ecosystem; D004777:Environment; D004784:Environmental Monitoring / Q000379:methods*; D007221:Industry; D007558:Italy; D018570:Risk Assessment / Q000379:methods; D014873:Water Pollutants / Q000032:analysis / Q000633:toxicity*
chemical_list: D014873:Water Pollutants
keywords: Environmental risk assessment; Genomics; Good environmental status; Ruditapes philippinarum; Venice lagoon