title: Do Asian women do as well as their Caucasian counterparts in IVF treatment: Cohort study.
abstract: OBJECTIVE
  To evaluate if there is a difference in pregnancy rate between Asian and Caucasian women when they undergo in vitro fertilization (IVF).
  
  
  METHODS
  This was a retrospective cohort study set in a private reproductive medicine clinic. The study consisted of a total of 2594 patients (Asian, n = 522; Caucasian, n = 2072) undergoing IVF managed by a single doctor over a 10 year period. The main outcome measures were clinical pregnancy rate and live birth rate. Logistic regression was used to control for confounding factors.
  
  
  RESULTS
  Asian women achieved a significantly lower clinical pregnancy and live birth rate than their Caucasian counterparts, despite replacement of more embryos. This difference was not significant after controlling for age and duration of infertility. Despite higher doses of gonadotrophin, they achieved fewer oocytes and had resultant fewer embryos for transfer or cryopreservation.
  
  
  CONCLUSIONS
  In a study designed to reduce the effect of confounding factors by looking at a large number of patients from a single IVF unit under the care of a single doctor, there does not appear to be a difference in IVF pregnancy rate as a result of race. Asian women tend to present for IVF treatment at a later age after having tried for a longer period of time and this contributes significantly to their lower pregnancy rate.
authors.affiliation: IVF Australia, Sydney, Australia.|School of Women's and Children's Health, University of NSW, North Ryde, Australia.
authors.forename: Andrew
authors.initials: A
authors.lastname: Kan
authors.affiliation: IVF Australia, Sydney, Australia.
authors.forename: Peter
authors.initials: P
authors.lastname: Leung
authors.affiliation: Department of Statistics, Macquarie University, North Ryde, Australia.
authors.forename: Kehui
authors.initials: K
authors.lastname: Luo
authors.affiliation: IVF Australia, Sydney, Australia.
authors.forename: Louise
authors.initials: L
authors.lastname: Fay
authors.affiliation: IVF Australia, Sydney, Australia.
authors.forename: Chunyan Leeann
authors.initials: CL
authors.lastname: Tan
mesh_terms: D000328:Adult; D000367:Age Factors; D044466:Asian People; D001723:Birth Rate / Q000208:ethnology; D015331:Cohort Studies; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects*; D006801:Humans; D007247:Infertility, Female / Q000208:ethnology / Q000503:physiopathology / Q000628:therapy*; D007248:Infertility, Male / Q000208:ethnology / Q000503:physiopathology / Q000628:therapy; D008297:Male; D009517:New South Wales / Q000453:epidemiology; D011247:Pregnancy; D018873:Pregnancy Rate / Q000208:ethnology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D056826:Single Embryo Transfer / Q000009:adverse effects*; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects*; D014504:Urban Health / Q000208:ethnology; D044465:White People
keywords: Asian; Caucasian; IVF; ethnicity; race