title: Isolation and characterization of Mayaro virus from a human in Acre, Brazil.
abstract: Mayaro virus (MAYV) is widely distributed throughout South America and is the etiologic agent of Mayaro fever, an acute febrile illness often presenting with arthralgic manifestations. The true incidence of MAYV infection is likely grossly underestimated because the symptomatic presentation is very similar to that of dengue fever and other acute febrile tropical diseases. We report the complete genome sequence of a MAYV isolate detected from an Acrelândia patient presenting with fever, chills, and sweating, but with no arthralgia. Results show that this isolate belongs to genotype D and is closely related to Bolivian strains. Our results suggest that the Acre/Mayaro strain is closely related to the progenitor of these Bolivian strains that were isolated between 2002 and 2006.
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: Ana Carolina B
authors.initials: AC
authors.lastname: Terzian
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: Albert J
authors.initials: AJ
authors.lastname: Auguste
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: Danila
authors.initials: D
authors.lastname: Vedovello
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: Marcelo U
authors.initials: MU
authors.lastname: Ferreira
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: Mônica
authors.initials: M
authors.lastname: da Silva-Nunes
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: Márcia A
authors.initials: MA
authors.lastname: Sperança
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: Rodrigo B
authors.initials: RB
authors.lastname: Suzuki
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: Camila
authors.initials: C
authors.lastname: Juncansen
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: João P
authors.initials: JP
authors.lastname: Araújo
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil.
authors.forename: Scott C
authors.initials: SC
authors.lastname: Weaver
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil; Institute for Human Infections and Immunity, Center for Tropical Diseases and Department of Pathology, University of Texas Medical Branch, Galveston, Texas; Instituto de Ciências Biológicas/Universidade de São Paulo, São Paulo, Brazil; Universidade Federal do ABC, Santo André, São Paulo, Brazil; Universidade Estadual Paulista, Botucatu, São Paulo, Brazil mnogueira@famerp.br.
authors.forename: Maurício L
authors.initials: ML
authors.lastname: Nogueira
mesh_terms: D000328:Adult; D000524:Alphavirus / Q000235:genetics / Q000302:isolation & purification*; D018354:Alphavirus Infections / Q000453:epidemiology* / Q000821:virology; D001483:Base Sequence; D001938:Brazil / Q000453:epidemiology; D005260:Female; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny