title: Biotransformation of agallochaexcoerin A by Aspergillus flavus.
abstract: Agallochaexcoerin A (1), a seco-manoyl oxide diterpenoid was metabolised by pathogenic fungus, Aspergillus flavus, in growth media to yield a new metabolite, termed agallochaexcoerin G (2). It was confirmed by using IR, UV, (1)H NMR and HR-ESI-MS techniques. This microbial bioconversion was achieved by unusual dehydration at C-4 position.
authors.affiliation: a Natural Products Chemistry Division, Indian Institute of Chemical Technology , Hyderabad 500607 , India.
authors.forename: Madhu Babu
authors.initials: MB
authors.lastname: Sura
authors.forename: Madhu
authors.initials: M
authors.lastname: Ankireddy
authors.forename: Mangala
authors.initials: M
authors.lastname: Gowri Ponnapalli
mesh_terms: D001231:Aspergillus flavus / Q000378:metabolism*; D001711:Biotransformation; D004224:Diterpenes / Q000737:chemistry / Q000378:metabolism*; D015394:Molecular Structure
chemical_list: D004224:Diterpenes; C000598484:agallochaexcoerin A; C475535:manoyl oxide
keywords: Agallochaexcoerin A; Aspergillus flavus; biotransformation; microbial dehydration; pathogenic fungus