title: Desktop MRI as a promising tool for mapping intra-aneurismal flow.
abstract: In this work we evaluate the performance of a 40-mm diameter bore 0.2T desktop Halbach tomograph to obtain 2D and 3D velocity maps for studying intra-aneurismal flow in the presence or absence of nitinol meshed implants with the aim of optimizing the flow diverter efficacy. Phantoms with known spatial velocity distribution were used to determine the performance of the MRI system. Maximum velocities of about 200mm/s could be measured with a precision of 1% at a spatial resolution of 0.5×0.5×1mm(3). This accuracy is suitable to evaluate in vitro intra-aneurismal flow under different conditions such as variable flow rates, different vessel-aneurysm geometry, as well as the influence of metallic flow diverters on the intra-aneurismal flow distribution. The information obtained non-invasively with desktop tomographs can be used to complement in vivo studies in order to decide the optimum flow diverter.
authors.affiliation: Institut für Technische und Makromolekulare Chemie, RWTH Aachen University, Worringerweg 1, 52062 Aachen, Germany.
authors.forename: Josefina
authors.initials: J
authors.lastname: Perlo
authors.affiliation: FaMAF-Universidad Nacional de Córdoba & IFEG-CONICET, Córdoba, Argentina.
authors.forename: Emilia V
authors.initials: EV
authors.lastname: Silletta
authors.affiliation: Institut für Technische und Makromolekulare Chemie, RWTH Aachen University, Worringerweg 1, 52062 Aachen, Germany. Electronic address: danieli@itmc.rwth-aachen.de.
authors.forename: Ernesto
authors.initials: E
authors.lastname: Danieli
authors.affiliation: Acandis GmbH u. Co. KG, Theodor-Fahrner-Strasse 6, 75177 Pforzheim, Germany.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Cattaneo
authors.affiliation: FaMAF-Universidad Nacional de Córdoba & IFEG-CONICET, Córdoba, Argentina.
authors.forename: Rodolfo H
authors.initials: RH
authors.lastname: Acosta
authors.affiliation: Institut für Technische und Makromolekulare Chemie, RWTH Aachen University, Worringerweg 1, 52062 Aachen, Germany.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Blümich
authors.affiliation: Magritek GmbH, Philipsstrasse 8, 52068 Aachen, Germany.
authors.forename: Federico
authors.initials: F
authors.lastname: Casanova
mesh_terms: D000783:Aneurysm / Q000503:physiopathology*; D001783:Blood Flow Velocity; D003198:Computer Simulation; D005898:Glass; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D002532:Intracranial Aneurysm / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008670:Metals; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D012828:Silicones / Q000737:chemistry; D012984:Software; D015607:Stents
chemical_list: D008670:Metals; D012828:Silicones
keywords: Aneurysm; Compact MRI; Flow; Flow diverter; Metallic stent