title: [A rapidly progressive orbital tumor in a seven-year-old girl revealing a primitive systemic vasculitis].
abstract: Orbital tumor lesions in pediatric population encompass a wide range of pathological processes, which are very different in etiology and prognosis. They usually require an emergency in histological diagnosis because of their quick growth. Beside malignant and benign tumors, the inflammatory pseudo-tumors group included dysimmune orbital involvement secondary to systemic vasculitis such as granulomatosis with polyangiitis (ex-Wegener's granulomatosis). We report the case of a seven-year-old girl suffering from a severe primitive ANCA vasculitis, revealed by an orbital mass.
authors.affiliation: Centre de pathologie Est, groupement hospitalier Est, 59, boulevard Pinel, 69500 Bron, France. Electronic address: cecile.picard@chu-lyon.fr.
authors.forename: Cécile
authors.initials: C
authors.lastname: Picard
authors.affiliation: Service de chirurgie maxillo-faciale et stomatologique pédiatrique, groupement hospitalier Est, 69677 Lyon, France.
authors.forename: Florent
authors.initials: F
authors.lastname: Borgnat
authors.affiliation: Service de rhumatologie pédiatrique, groupement hospitalier Est, 69677 Lyon, France.
authors.forename: Marie-Caroline
authors.initials: MC
authors.lastname: Chastang
authors.affiliation: Service d'oto-rhino-laryngologie pédiatrique, groupement hospitalier Est, 69677 Lyon, France.
authors.forename: Aude
authors.initials: A
authors.lastname: Fleury
authors.affiliation: Service d'imagerie du groupement hospitalier Est, 69677 Lyon, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Guibaud
authors.affiliation: Centre de pathologie Est, groupement hospitalier Est, 59, boulevard Pinel, 69500 Bron, France.
authors.forename: Frédérique
authors.initials: F
authors.lastname: Dijoud
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood; D001249:Asthma / Q000150:complications; D001991:Bronchitis / Q000150:complications; D002648:Child; D018450:Disease Progression; D005260:Female; D015432:Glomerulonephritis, Membranoproliferative / Q000209:etiology; D014890:Granulomatosis with Polyangiitis / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D007829:Laryngostenosis / Q000209:etiology; D016727:Orbital Pseudotumor / Q000209:etiology* / Q000473:pathology
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic
keywords: ANCA vasculitis; Children; Enfant; Granulomatose avec polyangéite (maladie de Wegener); Granulomatosis with polyangiitis (Wegener's granulomatosis); Orbital pseudo-tumor; Pseudo-tumeur orbitaire; Vascularite à ANCA