title: En route to disentangle the impact and neurobiological substrates of early vocalizations: learning from Rett syndrome.
abstract: Research on acoustic communication and its underlying neurobiological substrates has led to new insights about the functioning of central pattern generators (CPGs). CPG-related atypicalities may point to brainstem irregularities rather than cortical malfunctions for early vocalizations/babbling. The "vocal pattern generator," together with other CPGs, seems to have great potential in disentangling neurodevelopmental disorders and potentially predict neurological development.
authors.affiliation: Institute of Physiology,Research Unit iDN - Interdisciplinary Developmental Neuroscience,Medical University of Graz Austria,8010 Graz,Austria.peter.marschik@medunigraz.atchrista.einspieler@medunigraz.atwww.medunigraz.at/physiologie/pbmarschikwww.medunigraz.at/physiologie/ceinspieler.
authors.forename: Peter B
authors.initials: PB
authors.lastname: Marschik
authors.affiliation: Department of Neurology,Boston Children's Hospital and Harvard Medical School,Boston,MA 02115.walter.kaufmann@childrens.harvard.eduhttp://www.iddrc.org/childrens-hospital-boston/index.php/investigators/details/walter_e._kaufmann_md.
authors.forename: Walter E
authors.initials: WE
authors.lastname: Kaufmann
authors.affiliation: Center of Neurodevelopmental Disorders (KIND),Department of Women's and Children's Health,Karolinska Institutet,Astrid Lindgren Children's Hospital,Solna 171 76 Stockholm,Sweden.sven.bolte@ki.sewww.ki.se/kind.
authors.forename: Sven
authors.initials: S
authors.lastname: Bölte
authors.affiliation: School of Educational Psychology,Victoria University of Wellington,PO Box 600,Wellington 6012,New Zealand.jeff.sigafoos@vuw.ac.nzhttp://www.victoria.ac.nz/education/about/staff/ed-psy-ped-staff/jeff-sigafoos.
authors.forename: Jeff
authors.initials: J
authors.lastname: Sigafoos
authors.affiliation: Institute of Physiology,Research Unit iDN - Interdisciplinary Developmental Neuroscience,Medical University of Graz Austria,8010 Graz,Austria.peter.marschik@medunigraz.atchrista.einspieler@medunigraz.atwww.medunigraz.at/physiologie/pbmarschikwww.medunigraz.at/physiologie/ceinspieler.
authors.forename: Christa
authors.initials: C
authors.lastname: Einspieler
mesh_terms: D000819:Animal Communication; D000818:Animals; D005075:Biological Evolution; D003142:Communication; D006801:Humans; D011323:Primates / Q000502:physiology*; D013060:Speech / Q000502:physiology*