title: Correlation between penile cuff test and pressure-flow study in patients candidates for trans-urethral resection of prostate.
abstract: BACKGROUND
  Aim of this study was to make a comparison between penile cuff test (PCT) and standard pressure-flow study (PFS) in the preoperative evaluation of patients candidates for trans-urethral resection of prostate (TURP) for benign prostatic obstruction (BPO).
  
  
  METHODS
  We enrolled male patients with lower urinary tract symptoms candidates for TURP. Each of them underwent a PCT and a subsequent PFS. A statistical analysis was performed: sensitivity (SE), specificity (SP), positive predictive value (PPV), negative predictive value (NPV), likelihood ratio and ratio of corrected classified were calculated. Fisher exact test was used to evaluate relationships between PCT and maximal urine flow (Qmax): a p-value < 0.05 was considered statistically significant.
  
  
  RESULTS
  We enrolled 48 consecutive patients. Overall, at PCT 31 patients were diagnosed as obstructed and 17 patients as unobstructed. At the subsequent PFS, 21 out of 31 patients diagnosed as obstructed at PCT were confirmed to be obstructed; one was diagnosed as unobstructed; the remaining 9 patients appeared as equivocal. Concerning the 17 patients unobstructed at PCT, all of them were confirmed not to be obstructed at PFS, with 10 equivocal and 7 unobstructed. The rate of correctly classified patients at PCT was 79% (95%-CI 65%-90%). About detecting obstructed patients, PCT showed a SE of 100% and a SP of 63%. The PPV was 68%, while the NPV was 100%.
  
  
  CONCLUSIONS
  PCT can be an efficient tool in evaluating patients candidates for TURP. In particular, it showed good reliability in ruling out BPO because of its high NPV, with a high rate of correctly classified patients overall. Further studies on a huger number of patients are needed, including post-operative follow-up as well.
authors.affiliation: School of Specialization in Urology, University of Rome Tor Vergata, Viale Oxford, 81-00133 Rome, Italy. danielebianchimail@yahoo.it.
authors.forename: Daniele
authors.initials: D
authors.lastname: Bianchi
authors.forename: Angelo
authors.initials: A
authors.lastname: Di Santo
authors.forename: Gabriele
authors.initials: G
authors.lastname: Gaziev
authors.forename: Roberto
authors.initials: R
authors.lastname: Miano
authors.forename: Stefania
authors.initials: S
authors.lastname: Musco
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Vespasiani
authors.forename: Enrico
authors.initials: E
authors.lastname: Finazzi Agrò
mesh_terms: D000368:Aged; D003950:Diagnostic Techniques, Urological; D006801:Humans; D008297:Male; D008875:Middle Aged; D010413:Penis / Q000502:physiology; D011237:Predictive Value of Tests; D011312:Pressure; D011470:Prostatic Hyperplasia / Q000150:complications* / Q000601:surgery; D020728:Transurethral Resection of Prostate; D001748:Urinary Bladder Neck Obstruction / Q000175:diagnosis* / Q000209:etiology; D014554:Urination; D014563:Urodynamics