title: [Features of biochemical changes in blood serum according to the form of progression of idiopathic and dysplastic coxarthrosis].
abstract: Carried out biochemical studies of blood serum (collagenase activity, glycosamineglicans and hydroxyproline fractions) of 72 patients with hip idiopathic osteoarthrosis and 30 patients with dysplastic osteoarthrosis of the iv-th stage in.accordance with J. H. Kellgren and J. S. Lavrence depending on the form of pathologic process progression. It has been proved that both with idiopathic and dysplastic coxartrosis metabolism of basic protein of osteochonrous tissue was broken both in catabolic and in synthetic phase of this process. The most deep changes 1 of biochemical values (collagenase, free and proteinbinded hydroxyprolines, the content of glycosamines) have been observed with rapid form of course progression of idiopathic and dysplastic coxarthrosis. Definite appropriateness promotesin.patients better understanding of coxarthrosis pathogenese, development of diagnostic and medical measures for patients with this severe orthopedic pathology.
authors.forename: G V
authors.initials: GV
authors.lastname: Gaĭko
authors.forename: A M
authors.initials: AM
authors.lastname: Magomedov
authors.forename: A V
authors.initials: AV
authors.lastname: Kalashnikov
authors.forename: T A
authors.initials: TA
authors.lastname: Kuzub
authors.forename: L V
authors.initials: LV
authors.lastname: Polishchuk
mesh_terms: D017364:Collagenases / Q000097:blood*; D018450:Disease Progression; D006025:Glycosaminoglycans / Q000097:blood*; D006801:Humans; D006909:Hydroxyproline / Q000097:blood*; D015207:Osteoarthritis, Hip / Q000097:blood* / Q000201:enzymology / Q000473:pathology; D012720:Severity of Illness Index
chemical_list: D006025:Glycosaminoglycans; D017364:Collagenases; D006909:Hydroxyproline