title: Neutrophils in asthma--a review.
abstract: Asthma is a chronic inflammatory disease, with an array of cells involved in the pathogenesis of the disease. The role of neutrophils in the development of bronchial asthma is found to be complex, as they may trigger activation of immunocompetent cells and are a potent source of free oxygen radicals and enzymes participating in airway remodeling. The review highlights the role of neutrophils in bronchial asthma.
authors.affiliation: Department of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, Marszałkowska 24, 00-576 Warsaw, Poland. Electronic address: olga.ciepiela@wum.edu.pl.
authors.forename: Olga
authors.initials: O
authors.lastname: Ciepiela
authors.affiliation: Department of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, Marszałkowska 24, 00-576 Warsaw, Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Ostafin
authors.affiliation: Department of Laboratory Diagnostics and Clinical Immunology of Developmental Age, Medical University of Warsaw, Marszałkowska 24, 00-576 Warsaw, Poland.
authors.forename: Urszula
authors.initials: U
authors.lastname: Demkow
mesh_terms: D017209:Apoptosis / Q000502:physiology; D001249:Asthma / Q000503:physiopathology*; D016207:Cytokines / Q000378:metabolism; D005109:Extracellular Matrix / Q000378:metabolism; D006801:Humans; D009504:Neutrophils / Q000502:physiology*
chemical_list: D016207:Cytokines
keywords: Asthma; Interleukin 8; Neutrophil; Neutrophil extracellular trap