title: DNA methylation is a key factor in understanding differentiation phenotype in esophageal squamous cell carcinoma.
authors.affiliation: Department of Translational Oncology, National Cancer Center Research Institute, Tsukiji 5-1-1, Chuo-ku, Tokyo, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Komatsu
authors.forename: Hiroki
authors.initials: H
authors.lastname: Sasaki
mesh_terms: D051792:Basic Helix-Loop-Helix Proteins / Q000235:genetics*; D002294:Carcinoma, Squamous Cell / Q000235:genetics / Q000473:pathology*; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D004938:Esophageal Neoplasms / Q000235:genetics / Q000473:pathology*; D000077277:Esophageal Squamous Cell Carcinoma; D015972:Gene Expression Regulation, Neoplastic; D018398:Homeodomain Proteins / Q000235:genetics*; D006801:Humans; D011379:Prognosis
chemical_list: D051792:Basic Helix-Loop-Helix Proteins; D018398:Homeodomain Proteins; C417032:SIM2 protein, human; C099236:SIX1 protein, human
keywords: cancer stem cell; differentiation; esophageal squamous cell carcinoma; methylation; transcription factor