title: Fungal naphtho-γ-pyrones--secondary metabolites of industrial interest.
abstract: Naphtho-γ-pyrones (NGPs) are secondary metabolites mainly produced by filamentous fungi (Fusarium sp., Aspergillus sp.) that should be considered by industrials. Indeed, these natural biomolecules show various biological activities: anti-oxidant, anti-microbial, anti-cancer, anti-HIV, anti-hyperuricuric, anti-tubercular, or mammalian triacylglycerol synthesis inhibition which could be useful for pharmaceutical, cosmetic, and/or food industries. In this review, we draw an overview on the interest in studying fungal NGPs by presenting their biological activities and their potential values for industrials, their biochemical properties, and what is currently known on their biosynthetic pathway. Finally, we will present what remains to be discovered about NGPs.
authors.affiliation: Laboratoire de Génie Chimique, UMR 5503 CNRS/INPT/UPS, Université de Toulouse, INP-ENSAT, 1, avenue de l'Agrobiopôle, 31326, Castanet-Tolosan, France.
authors.forename: Elodie
authors.initials: E
authors.lastname: Choque
authors.forename: Youssef
authors.initials: Y
authors.lastname: El Rayess
authors.forename: José
authors.initials: J
authors.lastname: Raynal
authors.forename: Florence
authors.initials: F
authors.lastname: Mathieu
mesh_terms: D001230:Aspergillus / Q000378:metabolism*; D001709:Biotechnology / Q000379:methods; D005658:Fungi / Q000378:metabolism*; D005670:Fusarium / Q000378:metabolism*; D009281:Naphthalenes / Q000378:metabolism*; D011753:Pyrones / Q000378:metabolism*; D064210:Secondary Metabolism; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D009281:Naphthalenes; D011753:Pyrones