title: Mother-to-Children Plasmodium falciparum Asymptomatic Malaria Transmission at Saint Camille Medical Centre in Ouagadougou, Burkina Faso.
abstract: Background. Malaria's prevalence during pregnancy varies widely in parts of sub-Saharan Africa, including Burkina Faso. The objective of this study was to evaluate the incidence of mother-to-child malaria transmission during childbirth at St. Camille Medical Centre in the city of Ouagadougou. Methods. Two hundred and thirty-eight (238) women and their newborns were included in the study. Women consenting to participate in this study responded to a questionnaire that identified their demographic characteristics. Asymptomatic malaria infection was assessed by rapid detection test Acon (Acon Malaria Pf, San Diego, USA) and by microscopic examination of Giemsa-stained thick and thin smears from peripheral, placental, and umbilical cord blood. Birth weights were recorded and the biological analyses of mothers and newborns' blood were also performed. Results. The utilization of long-lasting insecticidal nets (LLINs) and intermittent preventive treatment with sulfadoxine-pyrimethamine (SP) were 86.6% and 84.4%, respectively. The parasitic infection rates of 9.5%, 8.9%, and 2.8% were recorded, respectively, for the peripheral, placental, and umbilical cord blood. Placental infection was strongly associated with the presence of parasites in the maternal peripheral blood and a parasite density of >1000 parasites/µL. Conclusion. The prevalence of congenital malaria was reduced but was associated with a high rate of mother-to-child malaria transmission.
authors.affiliation: Laboratory of Molecular Biology and Genetics (LABIOGENE), University of Ouagadougou, 03 P.O. Box 7021, Ouagadougou 03, Burkina Faso ; Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Zoenabo
authors.initials: Z
authors.lastname: Douamba
authors.affiliation: Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso ; University St. Thomas Aquinas of Ouagadougou, 06 P.O. Box 10212, Ouagadougou 06, Burkina Faso.
authors.forename: Nangnéré Ginette Laure
authors.initials: NG
authors.lastname: Dao
authors.affiliation: Laboratory of Molecular Biology and Genetics (LABIOGENE), University of Ouagadougou, 03 P.O. Box 7021, Ouagadougou 03, Burkina Faso ; Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso ; Saint Camille Medical Centre of Ouagadougou, 01 P.O Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Théodora Mahoukédé
authors.initials: TM
authors.lastname: Zohoncon
authors.affiliation: Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso ; Laboratory of Molecular and Cellular Biology, University of Science and Technique of Masuku (USTM), P.O. Box 943, Franceville, Gabon.
authors.forename: Cyrille
authors.initials: C
authors.lastname: Bisseye
authors.affiliation: Laboratory of Molecular Biology and Genetics (LABIOGENE), University of Ouagadougou, 03 P.O. Box 7021, Ouagadougou 03, Burkina Faso ; Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Tegwindé Rebeca
authors.initials: TR
authors.lastname: Compaoré
authors.affiliation: Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Jacques Gilbert
authors.initials: JG
authors.lastname: Kafando
authors.affiliation: Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Bavouma Charles
authors.initials: BC
authors.lastname: Sombie
authors.affiliation: Laboratory of Molecular Biology and Genetics (LABIOGENE), University of Ouagadougou, 03 P.O. Box 7021, Ouagadougou 03, Burkina Faso ; Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso ; Saint Camille Medical Centre of Ouagadougou, 01 P.O Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Djeneba
authors.initials: D
authors.lastname: Ouermi
authors.affiliation: Laboratory of Molecular Biology and Genetics (LABIOGENE), University of Ouagadougou, 03 P.O. Box 7021, Ouagadougou 03, Burkina Faso ; Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso ; Saint Camille Medical Centre of Ouagadougou, 01 P.O Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Florencia W
authors.initials: FW
authors.lastname: Djigma
authors.affiliation: Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso ; Saint Camille Medical Centre of Ouagadougou, 01 P.O Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Paul
authors.initials: P
authors.lastname: Ouedraogo
authors.affiliation: Saint Camille Medical Centre of Ouagadougou, 01 P.O Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Nadine
authors.initials: N
authors.lastname: Ghilat
authors.affiliation: Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso ; Saint Camille Medical Centre of Ouagadougou, 01 P.O Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Virginio
authors.identifier: 0000-0003-1024-7210
authors.initials: V
authors.lastname: Pietra
authors.affiliation: Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso ; Department of Biology, UNESCO Chair in Biotechnology, Laboratory of Immunology & Pathology, University of Rome Tor Vergata, Scientific Research Avenue snc, 00143 Rome, Italy.
authors.forename: Vittorio
authors.initials: V
authors.lastname: Colizzi
authors.affiliation: Laboratory of Molecular Biology and Genetics (LABIOGENE), University of Ouagadougou, 03 P.O. Box 7021, Ouagadougou 03, Burkina Faso ; Pietro Annigoni Biomolecular Research Centre (CERBA), 01 P.O. Box 364, Ouagadougou 01, Burkina Faso ; University St. Thomas Aquinas of Ouagadougou, 06 P.O. Box 10212, Ouagadougou 06, Burkina Faso ; Saint Camille Medical Centre of Ouagadougou, 01 P.O Box 364, Ouagadougou 01, Burkina Faso.
authors.forename: Jacques
authors.initials: J
authors.lastname: Simpore