title: Hand scanning optical coherence tomography imaging using encoder feedback.
abstract: We present a new method for generating micron-scale OCT images of interstitial tissue with a hand scanning probe and a linear optical encoder that senses probe movement relative to a fixed reference point, i.e., tissue surface. Based on this approach, we demonstrate high resolution optical imaging of biological tissues through a very long biopsy needle. Minor artifacts caused by tissue noncompliance are corrected using a software algorithm which detects the simple repetition of the adjacent A-scans. This hand-scanning OCT imaging approach offers the physician the freedom to access imaging sites of interest repeatedly.
authors.forename: Nicusor
authors.initials: N
authors.lastname: Iftimia
authors.forename: Gopi
authors.initials: G
authors.lastname: Maguluri
authors.forename: Ernest W
authors.initials: EW
authors.lastname: Chang
authors.forename: Shing
authors.initials: S
authors.lastname: Chang
authors.forename: John
authors.initials: J
authors.lastname: Magill
authors.forename: William
authors.initials: W
authors.lastname: Brugge
mesh_terms: D000465:Algorithms; D000818:Animals; D005246:Feedback; D007091:Image Processing, Computer-Assisted; D041623:Tomography, Optical Coherence / Q000295:instrumentation*