title: Xanthones from mangosteen (Garcinia mangostana): multi-targeting pharmacological properties.
abstract: OBJECTIVE
  This review focuses on mangosteen pericarp extracts, xanthones and derivatives for the future laboratory experiment and development in pharmacological aspects.
  
  
  METHODS
  All relevant literature databases were searched up to 2 March 2014. The search terms included mangosteen, xanthone, mangostin, and gatanin in all of the human, animal, in vitro and in vivo studies. Anti-intflammation, antioxidant, antibacterial, anticancer and antiulcer properties of each substance were the key parameters.
  
  
  RESULTS
  Xanthones are a group of oxygen-containing heterocyclic compounds including alpha-mangostin, gamma-mangostin, mangosteen extract, xanthone derivatives and synthetic xanthones, which provide remarkable and diverse pharmacological effects such as anticancer, antioxidant, anti-inflammatory and antimicrobial activities.
  
  
  CONCLUSIONS
  These xanthone compounds may play a major role in therapeutic treatment ofthe diseases but precise mechanisms ofaction are still unclear and needfurther investigation.
authors.forename: Sarawut
authors.initials: S
authors.lastname: Jindarat
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000975:Antioxidants / Q000627:therapeutic use*; D029762:Garcinia mangostana; D006801:Humans; D010936:Plant Extracts / Q000627:therapeutic use*; D044004:Xanthones / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D010936:Plant Extracts; D044004:Xanthones; C009689:xanthone