title: Clustal omega.
abstract: Clustal Omega is a package for making multiple sequence alignments of amino acid or nucleotide sequences, quickly and accurately. It is a complete upgrade and rewrite of earlier Clustal programs. This unit describes how to run Clustal Omega interactively from a command line, although it can also be run online from several sites. The unit describes a basic protocol for taking a set of unaligned sequences and producing a full alignment. There are also protocols for using an external HMM or iteration to help improve an alignment.
authors.affiliation: School of Medicine and Medical Science, Conway Institute, University College Dublin, Ireland.
authors.forename: Fabian
authors.initials: F
authors.lastname: Sievers
authors.affiliation: School of Medicine and Medical Science, Conway Institute, University College Dublin, Ireland.
authors.forename: Desmond G
authors.initials: DG
authors.lastname: Higgins
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D012984:Software
keywords: Clustal Omega; HMM; hidden Markov model; iteration; multiple sequence alignment