title: Sleep-disordered breathing, sleep duration, and childhood overweight: a longitudinal cohort study.
abstract: OBJECTIVE
  To examine independent associations between sleep-disordered breathing (SDB), sleep duration from birth through 6.75 years, and body mass index (BMI) through 15 years of age in a population-based cohort.
  
  
  METHODS
  The Avon Longitudinal Study of Parents and Children collected parent questionnaire data on child sleep duration and SDB symptoms from birth through 6.75 years and child BMI from the Avon Longitudinal Study of Parents and Children research clinics (n = 1899). For SDB, logistic regression models-minimal, confounder, and confounder + sleep duration adjusted-examined associations with BMI at 7, 10, and 15 years of age. For short sleep duration (≤10th percentile), comparable SDB-adjusted models examined associations with BMI at 15 years of age.
  
  
  RESULTS
  Children with the worst SDB symptoms vs asymptomatic children, had increased odds of overweight at 7 (OR = 2.08, 95% CI = 1.04-4.17), 10 (OR = 1.79, 95% CI = 1.02-3.16), and 15 years of age (OR = 2.25, 95% CI = 1.27-3.97) in models adjusted for sleep duration. Similarly, short sleep duration at ≈5-6 years was associated with overweight at 15 years, independent of SDB. Children with short sleep duration at 4.75 years were more likely to be overweight at 15 years in minimally (OR = 2.21, 95% CI = 1.52-3.20), confounder (OR = 1.99, 95% CI = 1.34-2.96), and SDB-adjusted (OR = 2.04, 95% CI = 1.36-3.04) models.
  
  
  CONCLUSIONS
  Both SDB and short sleep duration significantly and independently increase children's odds of becoming overweight. Findings underscore the potential importance of early identification and remediation of SDB, along with insufficient sleep, as strategies for reducing childhood obesity.
authors.affiliation: Department of Family Medicine and Social Medicine, Albert Einstein College of Medicine, Bronx, NY. Electronic address: Karen.bonuck@einstein.yu.edu.
authors.forename: Karen
authors.initials: K
authors.lastname: Bonuck
authors.affiliation: Sleep Disorders Center and Department of Neurology, University of Michigan, Ann Arbor, MI.
authors.forename: Ronald D
authors.initials: RD
authors.lastname: Chervin
authors.affiliation: Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.
authors.forename: Laura D
authors.initials: LD
authors.lastname: Howe
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D050177:Overweight / Q000453:epidemiology / Q000209:etiology*; D017286:Polysomnography; D012119:Respiration; D012189:Retrospective Studies; D012307:Risk Factors; D012890:Sleep / Q000502:physiology*; D012891:Sleep Apnea Syndromes / Q000150:complications*; D011795:Surveys and Questionnaires; D006113:United Kingdom / Q000453:epidemiology