title: Rare combination of familial adenomatous polyposis and gallbladder polyps.
abstract: Familial adenomatous polyposis is associated with a high incidence of malignancies in the upper gastrointestinal tract (particularly ampullary adenocarcinomas). However, few reports have described a correlation between familial adenomatous polyposis and gallbladder neoplasms. We present a case of a 60-year-old woman with familial adenomatous polyposis who presented with an elevated mass in the neck of the gallbladder (measuring 16 mm × 8 mm in diameter) and multiple small cholecystic polyps. She had undergone a total colectomy for ascending colon cancer associated with familial adenomatous polyposis 22 years previously. The patient underwent laparoscopic cholecystectomy under a preoperative diagnosis of multifocal gallbladder polyps. Pathologic examination of the resected gallbladder revealed more than 70 adenomatous lesions, a feature consistent with adenoma of the gallbladder. This case suggests a requirement for long-term surveillance of the biliary system in addition to the gastrointestinal tract in patients with familial adenomatous polyposis.
authors.affiliation: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchi, Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, Japan.
authors.forename: Yasuhisa
authors.initials: Y
authors.lastname: Mori
authors.affiliation: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchi, Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, Japan.
authors.forename: Norihiro
authors.initials: N
authors.lastname: Sato
authors.affiliation: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchi, Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, Japan.
authors.forename: Nobutaka
authors.initials: N
authors.lastname: Matayoshi
authors.affiliation: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchi, Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, Japan.
authors.forename: Toshihisa
authors.initials: T
authors.lastname: Tamura
authors.affiliation: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchi, Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, Japan.
authors.forename: Noritaka
authors.initials: N
authors.lastname: Minagawa
authors.affiliation: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchi, Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, Japan.
authors.forename: Kazunori
authors.initials: K
authors.lastname: Shibao
authors.affiliation: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchi, Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, Japan.
authors.forename: Aiichiro
authors.initials: A
authors.lastname: Higure
authors.affiliation: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchi, Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, Japan.
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Nakamoto
authors.affiliation: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchi, Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Taguchi
authors.affiliation: Yasuhisa Mori, Norihiro Sato, Nobutaka Matayoshi, Toshihisa Tamura, Noritaka Minagawa, Kazunori Shibao, Aiichiro Higure, Koji Yamaguchi, Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka 807-8555, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Yamaguchi
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D018256:Adenomatous Polyps / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D001706:Biopsy; D049448:Cholangiopancreatography, Magnetic Resonance; D017081:Cholecystectomy, Laparoscopic; D003082:Colectomy; D019160:Endosonography; D005260:Female; D005706:Gallbladder Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Adenoma; Adenomatous polyposis coli; Biliary system; Familial adenomatous polyposis; Gallbladder polyp