title: [Bowel preparation for colonoscopy. Any significant progress on the horizon?].
abstract: Colonoscopy is the method of choice for colorectal cancer screening. To be effective, screening colonoscopy must have high quality standards. The key element is the quality of the preparation. However, up to 20% of patients are inadequately prepared and, at present, anterograde washing is the least tolerated part of the procedure. In the choice of preparation, safety is a prerequisite and efficacy is a priority. Tolerance is a secondary but nevertheless influential factor in the quality of preparation and has consequently been the primary focus of many recent studies. In the last few years, a rapidly increasing number of studies have evaluated new drugs, dosages and adjuvant therapies to improve efficacy and tolerability. These studies have collaterally shown that inadequate preparation and lack of adherence to the prescribed regimen can be partially predicted, making it essential to identify this patient subgroup and invest the necessary effort in their instruction. New individualized and flexible approaches are expected for the different clinical scenarios. The search for the ideal colonoscopy preparation, which would be tolerable, safe and above all effective, remains open.
authors.affiliation: Unidad de Endoscopia, Servicio de Gastroenterología, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, España.
authors.forename: Liseth
authors.initials: L
authors.lastname: Rivero-Sánchez
authors.affiliation: Unidad de Endoscopia, Servicio de Gastroenterología, Institut Clínic de Malalties Digestives i Metabòliques, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, España. Electronic address: mpellise@clinic.ub.es.
authors.forename: María
authors.initials: M
authors.lastname: Pellisé
mesh_terms: D001726:Bisacodyl / Q000008:administration & dosage; D002400:Cathartics / Q000008:administration & dosage* / Q000009:adverse effects; D002951:Citrates / Q000008:administration & dosage; D019343:Citric Acid / Q000008:administration & dosage; D003113:Colonoscopy / Q000379:methods* / Q000639:trends; D015179:Colorectal Neoplasms / Q000175:diagnosis; D004043:Dietary Fiber; D055088:Early Detection of Cancer / Q000379:methods* / Q000639:trends; D005544:Forecasting; D006801:Humans; D009942:Organometallic Compounds / Q000008:administration & dosage; D010342:Patient Acceptance of Health Care; D010710:Phosphates / Q000008:administration & dosage; D010847:Picolines / Q000008:administration & dosage; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000009:adverse effects; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic; D012676:Senna Extract / Q000008:administration & dosage; D000081226:Sennosides; D007507:Therapeutic Irrigation
chemical_list: D002400:Cathartics; D002951:Citrates; D004043:Dietary Fiber; D009942:Organometallic Compounds; D010710:Phosphates; D010847:Picolines; D000081226:Sennosides; D001726:Bisacodyl; D019343:Citric Acid; D011092:Polyethylene Glycols; D012676:Senna Extract; C005701:picosulfate sodium; C110422:magnesium citrate; C018279:sodium phosphate
keywords: Calidad colonoscopia; Colonoscopy quality; Colorectal cancer screening; Cribado cáncer colorrectal; Cuestionario; Polietilenglicol; Polyethylene glycol; Preparación colonoscopia; Preparation colonoscopy; Questionnaire; Tolerabilidad; Tolerability