title: Recent progress on DNA based walkers.
abstract: DNA based synthetic molecular walkers are reminiscent of biological protein motors. They are powered by hybridization with fuel strands, environment induced conformational transitions, and covalent chemistry of oligonucleotides. Recent developments in experimental techniques enable direct observation of individual walkers with high temporal and spatial resolution. The functionalities of state-of-the-art DNA walker systems can thus be analyzed for various applications. Herein we review recent progress on DNA walker principles and characterization methods, and evaluate various aspects of their functions for future applications.
authors.affiliation: School of Mechanical Engineering, Purdue University, Mechanical Engineering Building, 585 Purdue Mall, West Lafayette, IN 47907, USA.
authors.forename: Jing
authors.initials: J
authors.lastname: Pan
authors.affiliation: School of Mechanical Engineering, Purdue University, Mechanical Engineering Building, 585 Purdue Mall, West Lafayette, IN 47907, USA.
authors.forename: Feiran
authors.initials: F
authors.lastname: Li
authors.affiliation: School of Mechanical Engineering, Purdue University, Mechanical Engineering Building, 585 Purdue Mall, West Lafayette, IN 47907, USA.
authors.forename: Tae-Gon
authors.initials: TG
authors.lastname: Cha
authors.affiliation: School of Mechanical Engineering, Purdue University, Mechanical Engineering Building, 585 Purdue Mall, West Lafayette, IN 47907, USA.
authors.forename: Haorong
authors.initials: H
authors.lastname: Chen
authors.affiliation: School of Mechanical Engineering, Purdue University, Mechanical Engineering Building, 585 Purdue Mall, West Lafayette, IN 47907, USA. Electronic address: jchoi@purdue.edu.
authors.forename: Jong Hyun
authors.initials: JH
authors.lastname: Choi
mesh_terms: D004247:DNA / Q000737:chemistry* / Q000235:genetics; D006801:Humans; D009693:Nucleic Acid Hybridization; D011506:Proteins / Q000235:genetics; D012313:RNA / Q000737:chemistry / Q000235:genetics; D015203:Reproducibility of Results
chemical_list: D011506:Proteins; D012313:RNA; D004247:DNA