title: Treatment of feline asthma with ciclosporin in a cat with diabetes mellitus and congestive heart failure.
abstract: A 5-year-old domestic shorthair cat that had been previously diagnosed with diabetes mellitus was presented for episodes of coughing and respiratory distress. Diagnostic testing revealed congestive heart failure secondary to hypertrophic cardiomyopathy and concurrent asthma. All clinical signs and eosinophilic airway inflammation resolved with oral ciclosporin while the cat was concurrently receiving medications for treatment of heart failure (furosemide and enalapril). Ciclosporin should be considered for treatment of feline asthma in patients with concurrent diseases (eg, diabetes mellitus, severe heart disease) that may contraindicate use of oral glucocorticoid therapy.
authors.affiliation: Department of Veterinary Clinical Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK, USA nafe@okstate.edu.
authors.forename: Laura A
authors.initials: LA
authors.lastname: Nafe
authors.affiliation: Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA.
authors.forename: Stacey B
authors.initials: SB
authors.lastname: Leach
mesh_terms: D000818:Animals; D001249:Asthma / Q000188:drug therapy / Q000662:veterinary*; D002312:Cardiomyopathy, Hypertrophic / Q000662:veterinary; D002371:Cat Diseases / Q000175:diagnosis / Q000188:drug therapy*; D002415:Cats; D016572:Cyclosporine / Q000627:therapeutic use*; D003920:Diabetes Mellitus / Q000662:veterinary; D004305:Dose-Response Relationship, Drug; D006333:Heart Failure / Q000662:veterinary; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine