title: Degree of polarization uniformity with high noise immunity using polarization-sensitive optical coherence tomography.
abstract: A new metric representing polarization uniformity is presented. Noise corrected degree of polarization uniformity (DOPU) is computed from polarization-sensitive optical coherence tomography (OCT), and selectively visualizes tissue with the multiple scattering, such as highly pigmented tissues. The new metric is designed to be minimally sensitive to systematic additive noise. The performance of this new metric is analyzed by numerical simulation and in vivo human retinal imaging, using Jones matrix OCT. The new metric exhibited only a small dependency on the signal-to-noise ratio. Selective in vivo visualization of pigmented tissues in the human retina is demonstrated, with cross sectional and en-face images.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Makita
authors.forename: Young-Joo
authors.initials: YJ
authors.lastname: Hong
authors.forename: Masahiro
authors.initials: M
authors.lastname: Miura
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Yasuno
mesh_terms: D006801:Humans; D007091:Image Processing, Computer-Assisted; D010860:Pigments, Biological / Q000378:metabolism; D012160:Retina / Q000378:metabolism; D059629:Signal-To-Noise Ratio; D041623:Tomography, Optical Coherence / Q000379:methods*
chemical_list: D010860:Pigments, Biological