title: [The role of histaminergic system of the brain in the regulation of sleep-wakefulness cycle].
abstract: The structure, morphological and neurochemical bindings ofhistaminergic system of the brain as one of the most important mechanisms of waking maintenance, are regarded. The biochemistry of histamine turnover and histamine receptors are briefly described. The special role of the relation between histamine and orexin/hypocretin systems is stressed. Some examples of the responses on wakefulness-sleep cycle of the effects of experimental manipulations with the histaminergic system are given.
authors.forename: V M
authors.initials: VM
authors.lastname: Koval'zon
mesh_terms: D001921:Brain / Q000502:physiology*; D001923:Brain Chemistry / Q000502:physiology; D006632:Histamine / Q000502:physiology*; D006801:Humans; D012890:Sleep / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology*
chemical_list: D006632:Histamine