title: Images of cell trees, cell lines, and cell fates: the legacy of Ernst Haeckel and August Weismann in stem cell research.
abstract: Stem cells did not become a proper research object until the 1960 s. Yet the term and the basic mind-set--namely the conception of single undifferentiated cells, be they embryonic or adult, as the basic units responsible for a directed process of development, differentiation and increasing specialisation--were already in place at the end of the nineteenth century and then transmitted on a non-linear path in the form of tropes and diagrams. Ernst Haeckel and August Weismann played a special role in this story. The first coined the term Stammzelle (stem cell), the second was the author of the first cellular stem-tree diagram. Even today, I shall argue, the understanding of stem cells, especially the popular perception, is to a large extent a Haeckelian-Weismannian one. After having demonstrated this, by analysing the terminology, in this essay I will focus on the use of cytogenetic tree diagrams between 1892 and 1925 and on the tacit understanding of stem cells that they transmit.
authors.forename: Ariane
authors.initials: A
authors.lastname: Dröscher
mesh_terms: D003585:Cell Biology / Q000266:history*; D002460:Cell Line; D005858:Germany; D049672:History, 19th Century; D057905:Stem Cell Research / Q000266:history*; D013234:Stem Cells