title: Developmental dyscalculia.
abstract: Numerical skills are essential in our everyday life, and impairments in the development of number processing and calculation have a negative impact on schooling and professional careers. Approximately 3 to 6 % of children are affected from specific disorders of numerical understanding (developmental dyscalculia (DD)). Impaired development of number processing skills in these children is characterized by problems in various aspects of numeracy as well as alterations of brain activation and brain structure. Moreover, DD is assumed to be a very heterogeneous disorder putting special challenges to define homogeneous diagnostic criteria. Finally, interdisciplinary perspectives from psychology, neuroscience and education can contribute to the design for interventions, and although results are still sparse, they are promising and have shown positive effects on behaviour as well as brain function.
  
  
  CONCLUSIONS
  In the current review, we are going to give an overview about typical and atypical development of numerical abilities at the behavioural and neuronal level. Furthermore, current status and obstacles in the definition and diagnostics of DD are discussed, and finally, relevant points that should be considered to make an intervention as successful as possible are summarized.
authors.affiliation: Center for MR-Research, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland, karin.kucian@kispi.uzh.ch.
authors.forename: Karin
authors.initials: K
authors.lastname: Kucian
authors.forename: Michael
authors.initials: M
authors.lastname: von Aster
mesh_terms: D001921:Brain / Q000473:pathology; D002648:Child; D002658:Developmental Disabilities / Q000175:diagnosis* / Q000628:therapy; D060705:Dyscalculia / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D055641:Mathematical Concepts; D009483:Neuropsychological Tests