title: Computer aided-diagnosis of prostate cancer on multiparametric MRI: a technical review of current research.
abstract: Prostate cancer (PCa) is the most commonly diagnosed cancer among men in the United States. In this paper, we survey computer aided-diagnosis (CADx) systems that use multiparametric magnetic resonance imaging (MP-MRI) for detection and diagnosis of prostate cancer. We review and list mainstream techniques that are commonly utilized in image segmentation, registration, feature extraction, and classification. The performances of 15 state-of-the-art prostate CADx systems are compared through the area under their receiver operating characteristic curves (AUC). Challenges and potential directions to further the research of prostate CADx are discussed in this paper. Further improvements should be investigated to make prostate CADx systems useful in clinical practice.
authors.affiliation: Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Building 10, Room 1C224, Bethesda, MD 20892-1182, USA.
authors.forename: Shijun
authors.identifier: 0000-0002-2873-8432
authors.initials: S
authors.lastname: Wang
authors.affiliation: Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Building 10, Room 1C224, Bethesda, MD 20892-1182, USA.
authors.forename: Karen
authors.identifier: 0000-0003-4041-0488
authors.initials: K
authors.lastname: Burtt
authors.affiliation: Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Building 10, Room B3B69F, Bethesda, MD 20892-1088, USA.
authors.forename: Baris
authors.initials: B
authors.lastname: Turkbey
authors.affiliation: Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Building 10, Room B3B69F, Bethesda, MD 20892-1088, USA.
authors.forename: Peter
authors.initials: P
authors.lastname: Choyke
authors.affiliation: Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Building 10, Room 1C224, Bethesda, MD 20892-1182, USA.
authors.forename: Ronald M
authors.initials: RM
authors.lastname: Summers
mesh_terms: D003936:Diagnosis, Computer-Assisted; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D011859:Radiography