title: Carboxymethyl cellulose/silica hybrids as templates for calcium phosphate biomimetic mineralization.
abstract: Multiphase hybrid materials were synthesized using carboxymethyl cellulose (CMC) as bioactive polymer, silica gel as matrix assisted networks and calcium phosphate as inorganic mineral phase. These hybrids were investigated with infrared spectroscopy, X-ray diffraction, scanning electron microscopy, energy dispersive X-ray spectroscopy and transmission electron microscopy. Biomimetic crystal growth nucleated from the CMC/silica hybrids was suggested as amorphous calcium phosphate with an evidence that hydroxyapatite, the mineralized component of bone, may be formed at high CMC content. This study provides an efficient approach toward bone-like hybrids with potential bone healing applications.
authors.affiliation: Cellulose and Paper Department, National Research Center, El-Tahrir Street, Dokki, Cairo, Egypt. Electronic address: ahmed_nigm78@yahoo.com.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Salama
authors.affiliation: Cellulose and Paper Department, National Research Center, El-Tahrir Street, Dokki, Cairo, Egypt.
authors.forename: Ragab E
authors.initials: RE
authors.lastname: Abou-Zeid
authors.affiliation: Cellulose and Paper Department, National Research Center, El-Tahrir Street, Dokki, Cairo, Egypt.
authors.forename: Mohamed
authors.initials: M
authors.lastname: El-Sakhawy
authors.affiliation: Cellulose and Paper Department, National Research Center, El-Tahrir Street, Dokki, Cairo, Egypt.
authors.forename: Ahmed
authors.initials: A
authors.lastname: El-Gendy
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D032701:Biomimetics; D002130:Calcium Phosphates / Q000737:chemistry*; D002266:Carboxymethylcellulose Sodium / Q000737:chemistry*; D008422:Materials Testing; D055595:Mechanical Phenomena; D012822:Silicon Dioxide / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; D012822:Silicon Dioxide; C020243:calcium phosphate; D002266:Carboxymethylcellulose Sodium
keywords: Bioactivity; Calcium phosphate; Carboxymethyl cellulose; Hybrid; Sol–gel