title: P2X receptors and inflammation.
abstract: Until recently, P2X receptors have not received much attention in the context of immunology and inflammation. While this is justified to a certain extent for P2X1, P2X2, P2X3, P2X5 and P2X6, which still await identification of a convincing role in the pathophysiology of immune cells, it is clearly not any more the case for P2X4 and even more so for P2X7, a molecule that has achieved the status of an essential, nonredundant, immunomodulatory receptor. In this review I will highlight the most important inflammatory responses participated by P2X receptors.
authors.affiliation: Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Via Borsari 46, University of Ferrara, Ferrara, Italy. fdv@unife.it.
authors.forename: Francesco
authors.initials: F
authors.lastname: Di Virgilio
mesh_terms: D000818:Animals; D006801:Humans; D007249:Inflammation / Q000378:metabolism*; D058469:Receptors, Purinergic P2X / Q000378:metabolism*
chemical_list: D058469:Receptors, Purinergic P2X