title: Comparison on the Effects and Safety of Tualang Honey and Tribestan in Sperm Parameters, Erectile Function, and Hormonal Profiles among Oligospermic Males.
abstract: Introduction. This study aims to evaluate the effectiveness of Tualang honey on sperm parameters, erectile function, and hormonal and safety profiles. Methodology. A randomized control trial was done using Tualang honey (20 grams) and Tribestan (750 mg) over a period of 12 weeks. Sperm parameters including sperm concentration, motility, and morphology were analyzed and erectile function was assessed using IIEF-5 questionnaire. Hormonal profiles of testosterone, FSH, and LH were studied. The volunteers were randomized into two groups and the outcomes were analyzed using SPSS version 18. Results. A total of 66 participants were involved. A significant increment of mean sperm concentration (P < 0.001), motility (P = 0.015) and morphology (P = 0.008) was seen in Tualang honey group. In Tribestan group, a significant increment of mean sperm concentration (P = 0.007), and morphology (P = 0.009) was seen. No significant differences of sperm concentration, motility, and morphology were seen between Tualang honey and Tribestan group and similar results were also seen in erectile function and hormonal profile. All safety profiles were normal and no adverse event was reported. Conclusion. Tualang honey effect among oligospermic males was comparable with Tribestan in improving sperm concentration, motility, and morphology. The usage of Tualang honey was also safe with no reported adverse event.
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Shaiful Bahari
authors.initials: SB
authors.lastname: Ismail
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Mohd Bustamanizan
authors.initials: MB
authors.lastname: Bakar
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Nik Hazlina
authors.initials: NH
authors.lastname: Nik Hussain
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Mohd Noor
authors.identifier: 0000-0002-6372-1476
authors.initials: MN
authors.lastname: Norhayati
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Siti Amrah
authors.initials: SA
authors.lastname: Sulaiman
authors.affiliation: School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia.
authors.forename: Hasnan
authors.initials: H
authors.lastname: Jaafar
authors.affiliation: International Islamic University, Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia.
authors.forename: Samsul
authors.initials: S
authors.lastname: Draman
authors.affiliation: International Islamic University, Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia.
authors.forename: Roszaman
authors.initials: R
authors.lastname: Ramli
authors.affiliation: Hospital Raja Perempuan Zainab II, 15200 Kota Bharu, Kelantan, Malaysia.
authors.forename: Wan Zahanim
authors.initials: WZ
authors.lastname: Wan Yusoff