title: Coronary artery stents: advances in technology.
abstract: The introduction of percutaneous coronary intervention (PCI) in the late 1970s revolutionized the management of stable and unstable coronary artery disease, providing an effective, quick, safe, and increasingly widely available method for coronary revascularization for many patients. Rapid development in this field led to the introduction of a number of new technologies, including intracoronary stents that have resulted in improved efficacy and long-term safety. In this manuscript we review the experience with the 2 major available classes of stents (bare metal [BMS], drug-eluting [DES]) and describe the delivery systems for these stents. An evidence review of the large trial data comparing balloon angioplasty, BMS, and DES demonstrates the incremental advances over time, with the latest generation of DES achieving the lowest rates of restenosis, stent thrombosis, and recurrent myocardial infarction. In addition, we provide an overview of the latest developments in stent technology, including the introduction of bioresorbable stents and new stent delivery systems. These latest advances are hoped to further improve outcomes while reducing costs due to a reduction in the need for future procedures and hospitalizations due to recurrent coronary disease.
authors.affiliation: Department of Medicine, Brigham and Women's Hospital, Boston, MA.
authors.forename: Sameer D
authors.initials: SD
authors.lastname: Sheth
authors.forename: Robert P
authors.initials: RP
authors.lastname: Giugliano
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D035843:Biomedical Research; D003327:Coronary Disease / Q000628:therapy*; D003331:Coronary Vessels; D054855:Drug-Eluting Stents; D006801:Humans; D011474:Prosthesis Design; D015607:Stents / Q000639:trends*