title: [Long-term survival metastatic ovarian cancer elderly patient].
abstract: Ovarian cancer is the sixth diagnosed cancer among women worldwide, it has a high mortality and in most cases it's diagnosed in advanced stage (stage III-IV). Combination platinum-paclitaxel chemotherapy administered every 3 weeks is considered the gold standard for first-line treatment of patients with advanced ovarian cancer. Elderly patients with ovarian cancer represents a subgroup with poor prognosis because they are often treated less radically for comorbidities and age. In the present article, we report a case of a 85 year old woman who was diagnosed with stage IV ovarian carcinoma for the presence of peritoneal carcinomatosis ab initio, not radically debulked and then treated with weekly schedule platinum-based and paclitaxel. Despite not being able to complete the chemotherapy, the patient achieved excellent results and represents a case of long survival.
authors.affiliation: Dipartimento di Medicina Sperimentale, Università Sapienza, Roma.
authors.forename: L
authors.initials: L
authors.lastname: Amoroso
authors.affiliation: Dipartimento di Medicina Sperimentale, Università Sapienza, Roma.
authors.forename: F
authors.initials: F
authors.lastname: De Iuliis
authors.affiliation: Dipartimento di Medicina Sperimentale, Università Sapienza, Roma.
authors.forename: L
authors.initials: L
authors.lastname: Taglieri
authors.affiliation: Dipartimenti di Radiologia, Oncologia e Anatomia Patologica, Università Sapienza, Roma.
authors.forename: S
authors.initials: S
authors.lastname: Vendittozzi
authors.affiliation: Dipartimento di Medicina Sperimentale, Università Sapienza, Roma.
authors.forename: G
authors.initials: G
authors.lastname: Salerno
authors.affiliation: Dipartimento di Radioterapia Oncologica, Ospedale S. Andrea, Università Sapienza, Roma.
authors.forename: L
authors.initials: L
authors.lastname: Blasi
authors.affiliation: Policlinico Umberto I, Roma, Italia.
authors.forename: R
authors.initials: R
authors.lastname: Lanza
mesh_terms: D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016190:Carboplatin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D009375:Neoplasms, Glandular and Epithelial / Q000473:pathology* / Q000556:secondary* / Q000628:therapy; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000628:therapy; D017239:Paclitaxel / Q000008:administration & dosage; D010534:Peritoneal Neoplasms / Q000556:secondary* / Q000628:therapy
chemical_list: D016190:Carboplatin; D017239:Paclitaxel
keywords: Carboplatin; Elderly patient; Metastatic disease; Ovarian cancer; Paclitaxel; Peritoneal carcinosis