title: Adiposis dolorosa.
abstract: We report a 46-year-old woman with a nine-year history of obesity; chronic diffuse pain in the adipose tissue of her medial upper arms, lower trunk, and thighs; multiple biopsy-proven lipomas and angiolipomas; and a lipomatous pseudomass of the breast. Her systemic symptoms included generalized weakness, fatigue, memory impairment, and arthralgias. Although some of the lesions were tender, most were only appreciated with palpation. Her clinical history and histopathologic data suggested adiposis dolorosa (Dercum's disease). Owing to the chronic pain, an interdisciplinary approach with the use of analgesics and doxycycline has been initiated.
authors.affiliation: New York University School of Medicine.
authors.forename: Panta Rouhani
authors.initials: PR
authors.lastname: Schaffer
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Hale
authors.forename: Shane A
authors.initials: SA
authors.lastname: Meehan
authors.forename: Jerome L
authors.initials: JL
authors.lastname: Shupack
authors.forename: Sarika
authors.initials: S
authors.lastname: Ramachandran
mesh_terms: D000274:Adiposis Dolorosa / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged