title: Brain expression of pCREB in rats exposed to consummatory successive negative contrast.
abstract: A 32-to-4% sucrose devaluation leads to suppression of consummatory behavior relative to unshifted 4% sucrose controls. This is accompanied by an emotional response inducing memory consolidation. Expression levels of phosphorylated cyclic adenosine monophosphate response element-binding protein (pCREB, a marker of synaptic plasticity) were higher after the first devaluation session than after the second in prelimbic cortex, anterior cingulate cortex, and dorso-medial striatum. The central nucleus of the amygdala showed a tendency to differential pCREB expression. This evidence contributes to identifying the brain circuit for one form of traumatic memory involving reward loss.
authors.affiliation: Department of Psychology, Texas Christian University, Fort Worth, TX 76129, USA.
authors.forename: Amanda C
authors.initials: AC
authors.lastname: Glueck
authors.affiliation: Department of Psychology, University of Texas at Arlington, Arlington, TX 76019, USA.
authors.forename: Torry S
authors.initials: TS
authors.lastname: Dennis
authors.affiliation: Department of Psychology, University of Texas at Arlington, Arlington, TX 76019, USA.
authors.forename: Linda I
authors.initials: LI
authors.lastname: Perrotti
authors.affiliation: Department of Psychology, University of Jaén, 23071 Jaén, Spain.
authors.forename: Carmen
authors.initials: C
authors.lastname: Torres
authors.affiliation: Department of Psychology, Texas Christian University, Fort Worth, TX 76129, USA. Electronic address: m.papini@tcu.edu.
authors.forename: Mauricio R
authors.initials: MR
authors.lastname: Papini
mesh_terms: D000818:Animals; D001921:Brain / Q000033:anatomy & histology / Q000378:metabolism*; D003259:Consummatory Behavior; D017362:Cyclic AMP Response Element-Binding Protein / Q000378:metabolism*; D008297:Male; D010766:Phosphorylation; D017208:Rats, Wistar; D013395:Sucrose / Q000008:administration & dosage
chemical_list: D017362:Cyclic AMP Response Element-Binding Protein; D013395:Sucrose
keywords: Anterior cingulate; Consummatory successive negative contrast; Dorsal striatum; Memory consolidation; Prelimbic cortex; pCREB