title: [Helicobacter pylori infection in patients with functional dyspepsia, eradication rates in the Donetsk region].
abstract: We have investigated 175 patients with Rome III diagnostic criteria for functional dyspepsia. 104 (59%) patients were infected with Helicobacter pylori. Three-component (PPI + clarithromycin + amoxicillin) 7-day therapy with the addition of the probiotic was effective in 92 patients (88.4%). Dyspeptic symptoms were resolved in 37 patients with successful eradication (40%). Persistent effect for 6 months was maintained in 24 patients (26%). Eradication efficacy in eliminating of the dyspepsia symptoms was higher in epigastric pain syndrome than postprandial distress syndrome.
authors.forename: A É
authors.initials: AÉ
authors.lastname: Dorofeev
authors.forename: N N
authors.initials: NN
authors.lastname: Rudenko
authors.forename: A N
authors.initials: AN
authors.lastname: Agibalov
authors.forename: T E
authors.initials: TE
authors.lastname: Kugler
authors.forename: A V
authors.initials: AV
authors.lastname: Sibilev
authors.forename: O V
authors.initials: OV
authors.lastname: Tomash
mesh_terms: D015746:Abdominal Pain / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017291:Clarithromycin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004415:Dyspepsia / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D005260:Female; D005756:Gastritis / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D016481:Helicobacter Infections / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D016480:Helicobacter pylori / Q000187:drug effects / Q000254:growth & development; D006801:Humans; D008297:Male; D019936:Probiotics / Q000627:therapeutic use; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D054328:Proton Pump Inhibitors; D000658:Amoxicillin; D017291:Clarithromycin