title: Arsenolipids in oil from blue whiting Micromesistius poutassou--evidence for arsenic-containing esters.
abstract: Arsenic-containing lipids in the oil from the blue whiting fish (Micromesistius poutassou) were separated into three broad polarity groups and investigated by HPLC and mass spectrometry. A total of 11 arsenolipids including 4 new compounds were identified. The polar lipid fraction constituting 24% of the total arsenolipid content (which totalled 2.16 μg As/g) contained four known dimethylarsinoyl fatty acids and three known dimethylarsinoyl hydrocarbons. The less polar fraction (ca 30% of the total arsenolipids) contained four new dimethylarsinoyl hydrocarbons with chain lengths 22-30 carbons, in addition to more complex arsenicals that hydrolysed to known dimethylarsinoyl fatty acids suggesting they were conjugated carboxylic acids, presumably esters. The rest of the lipid-soluble arsenic (ca 45% of the total) remained in the non-polar fraction together with the bulk of the fish oil lipids, a complex mixture of compounds that precluded identification of the small amounts of arsenolipids.
authors.affiliation: 1] Institute of Chemistry-Analytical Chemistry, University of Graz, Universitaetsplatz 1, 8010 Graz, Austria [2] Department of Marine Chemistry, Faculty of Marine Science, University of Mazandaran, Babolsar, Iran.
authors.forename: Mojtaba S
authors.initials: MS
authors.lastname: Taleshi
authors.affiliation: Institute of Chemistry-Analytical Chemistry, University of Graz, Universitaetsplatz 1, 8010 Graz, Austria.
authors.forename: Georg
authors.initials: G
authors.lastname: Raber
authors.affiliation: Institute of Chemistry-Analytical Chemistry, University of Graz, Universitaetsplatz 1, 8010 Graz, Austria.
authors.forename: John S
authors.initials: JS
authors.lastname: Edmonds
authors.affiliation: Institute of Chemistry-Analytical Chemistry, University of Graz, Universitaetsplatz 1, 8010 Graz, Austria.
authors.forename: Kenneth B
authors.initials: KB
authors.lastname: Jensen
authors.affiliation: Institute of Chemistry-Analytical Chemistry, University of Graz, Universitaetsplatz 1, 8010 Graz, Austria.
authors.forename: Kevin A
authors.initials: KA
authors.lastname: Francesconi
mesh_terms: D000818:Animals; D001151:Arsenic / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid; D004952:Esters / Q000737:chemistry*; D005395:Fish Oils / Q000737:chemistry*; D005399:Fishes; D006838:Hydrocarbons / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D008055:Lipids / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D004952:Esters; D005395:Fish Oils; D006838:Hydrocarbons; D008055:Lipids; D001151:Arsenic