title: Prevalence and characteristics of colorectal polyps in symptomatic and asymptomatic Iranian patients undergoing colonoscopy from 2009-2013.
abstract: BACKGROUND
  Colorectal cancer is the third most common type of cancer in males and the second in females in Iran. Males are more likely to develop CRC than women and age is considered as a main risk factor for colorectal cancer. Prevalence of colorectal cancer has been increasing in Asian countries.
  
  
  OBJECTIVE
  The object of this study was to determine the clinical and pathology characteristics of colorectal polyps in Iranian patients and to investigate the variation between our populations with other populations.
  
  
  METHODS
  A total of 167 patients with colorectal polyps were included in our study. All underwent colonoscopy during 2009-2013 and specimens were taken through polypectomy and transferred to pathology. All data in patient files including pathology reports were collected and analyzed by SPSS 16 software. A two-tailed test was used and a P-value of <0.05 was considered significant.
  
  
  RESULTS
  Mean age of participants was 57±15. Some 84 were females (50.3%) and 83 males (49.7%). Total of 225 polyps were detected which 119 (52.9%) were in males and 106 (47.1%) were in females. Solitary polyps were observed in 124 patients (74%), 26 (15.6%) had two polyps and 17 (10.1%) with more than two polyps (three to five). Rectosigmoid was the site of most of the polyps (63.1%), followed by 19.6% in the descending colon, 7.6% in the transverse, 5.8% in the ascending, and 3.1% in the cecum, data being missing in two cases.
  
  
  CONCLUSIONS
  Recto sigmoid was site of most of the polyps. The most prevalent type of lesion was adenomatous polyps detected in 78 (34.7%). Mixed hyperplastic adenomatous type observed in 70 (31.1%). This high prevalence of adenomatous polyps in Iranian patients implies the urgent need for screening plans to prevent further healthcare problems with colorectal cancer in the Iranian population.
authors.affiliation: AJA Cancer Research Center (ACRC) AJA University of Medical Sciences, Tehran, Iran E-mail : azimzadeh.pedram@yahoo.com.
authors.forename: Shahrokh
authors.initials: S
authors.lastname: Iravani
authors.forename: Seyed Mohammad Hossein
authors.initials: SM
authors.lastname: Kashfi
authors.forename: Pedram
authors.initials: P
authors.lastname: Azimzadeh
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Lashkari
mesh_terms: D000236:Adenoma / Q000453:epidemiology / Q000473:pathology*; D018256:Adenomatous Polyps / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D000328:Adult; D003111:Colonic Polyps / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D015995:Prevalence; D011379:Prognosis; D013997:Time Factors