title: Mixed ovarian germ cell tumor composed of immature teratoma, yolk sac tumor and embryonal carcinoma.
abstract: We report the case of a 19-year-old woman experiencing lower abdominal distension and pain. Laboratory tests indicated elevated serum levels of Alpha-Fetoprotein (AFP) and human Chorionic Gonadotropin (hCG). A large mass was detected in the abdomen by physical examination and by transvaginal ultrasonography. Exploratory laparotomy was performed, and a smooth-surfaced, spherical, solid tumor was found on the left ovary, measuring 11.5 x 9.9 x 6.9 cm. Histological evaluation revealed that the tumor consisted of a combination of immature teratoma, Yolk Sac Tumor, and embryonal carcinoma; this is a very rare combination in mixed germ cell tumors.
authors.affiliation: Department of Obstetrics and Gynecology, The Family Planning Publicity and Technical Guidance Station, Yiwu City, Zhejiang Province, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Pathology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Zhou
authors.affiliation: Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China.
authors.forename: Zhida
authors.initials: Z
authors.lastname: Qian
authors.affiliation: Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China.
authors.forename: Jiale
authors.initials: J
authors.lastname: Qing
authors.affiliation: Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China.
authors.forename: Mengdam
authors.initials: M
authors.lastname: Zhao
authors.affiliation: Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China.
authors.forename: Lili
authors.initials: L
authors.lastname: Huang
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000627:therapeutic use; D018236:Carcinoma, Embryonal / Q000097:blood / Q000473:pathology* / Q000628:therapy; D017024:Chemotherapy, Adjuvant / Q000379:methods; D006063:Chorionic Gonadotropin / Q000097:blood; D002945:Cisplatin / Q000627:therapeutic use; D018240:Endodermal Sinus Tumor / Q000097:blood / Q000473:pathology* / Q000628:therapy; D005047:Etoposide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007813:Laparotomy; D018193:Neoplasms, Complex and Mixed / Q000097:blood / Q000473:pathology* / Q000628:therapy; D009373:Neoplasms, Germ Cell and Embryonal / Q000097:blood / Q000473:pathology* / Q000628:therapy; D010051:Ovarian Neoplasms / Q000097:blood / Q000473:pathology* / Q000628:therapy; D010052:Ovariectomy; D012489:Salpingostomy; D013724:Teratoma / Q000097:blood / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome; D055815:Young Adult; D000509:alpha-Fetoproteins / Q000032:analysis / Q000378:metabolism
chemical_list: D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins; D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin