title: [Pachymetry and intraocular pressure measurement by corneal visualization Scheimpflug technology (Corvis ST): A clinical comparison to the gold standard].
abstract: BACKGROUND
  Analyses regarding accuracy and reproducibility of intraocular pressure (IOP) measurements and pachymetry with corneal visualization Scheimpflug technology (Corvis ST®, CST).
  
  
  METHODS
  Retrospective analysis of 72 eyes with primary open angle glaucoma (POAG) and ocular hypertension (OHT) with no prior surgery or other pathology. The results of Goldmann applanation tonometry (GAT), non-contact tonometry (NCT) and ultrasound pachymetry (USP) were compared with repeat measurements with CST. For statistical analyses the t-test and Bland-Altman plots were applied.
  
  
  RESULTS
  The mean IOP was 15.5 ± 4.4 mmHg (CST), 14.8 ± 4.4 mmHg (GAT) and 15.6 ± 4.8 mmHg (NCT). The results of GAT and CST as well as GAT and NCT demonstrated statistically significant differences (p < 0.001) whereas NCT and CST displayed no significant differences in IOP (p = 0.72). The mean differences between the repeat measurements were 0.35 ± 1.7 mmHg (CST) and 0.04 ± 0.85 mmHg (GAT). The mean CST pachymetry results showed 551.3 ± 46.5 µm and the USP 526.5 ± 46.4 µm (p < 0.001). The mean difference between the repeated CST measurements was 24.8 ± 21 µm. No repeat measurement data were available for USP.
  
  
  CONCLUSIONS
  The CST is a new device for simultaneously measuring the IOP, pachymetry and biomechanical properties of the cornea. Whether the deviations in the IOP measured by CST and CST pachymetry from the manually performed gold standard has to be evaluated as deficient, tolerable or maybe as an improvement, has to be evaluated in further studies. Because of the automated and contact-free measurement method as well as the potential for simultaneously analyzing biomechanical properties of the cornea, the CST is a device that might help the quest for measuring the 'true' IOP.
authors.affiliation: Augenklinik, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistr. 52, 20246, Hamburg, Deutschland. steinberg@zentrumsehstaerke.de.|Care-Vision Hamburg, Hamburg, Deutschland. steinberg@zentrumsehstaerke.de.
authors.forename: J
authors.initials: J
authors.lastname: Steinberg
authors.affiliation: Augenklinik, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistr. 52, 20246, Hamburg, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Mehlan
authors.affiliation: Augenklinik, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistr. 52, 20246, Hamburg, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Frings
authors.affiliation: Augenklinik, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistr. 52, 20246, Hamburg, Deutschland.
authors.forename: V
authors.initials: V
authors.lastname: Druchkiv
authors.affiliation: Augenklinik, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistr. 52, 20246, Hamburg, Deutschland.
authors.forename: G
authors.initials: G
authors.lastname: Richard
authors.affiliation: Augenklinik, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistr. 52, 20246, Hamburg, Deutschland.|Care-Vision Hamburg, Hamburg, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Katz
authors.affiliation: Augenklinik, Universitätsklinikum Hamburg-Eppendorf (UKE), Martinistr. 52, 20246, Hamburg, Deutschland.|Care-Vision Hamburg, Hamburg, Deutschland.
authors.forename: S J
authors.initials: SJ
authors.lastname: Linke
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea / Q000473:pathology / Q000503:physiopathology*; D063171:Corneal Pachymetry / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005901:Glaucoma / Q000175:diagnosis* / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014065:Tonometry, Ocular / Q000295:instrumentation* / Q000379:methods
keywords: Cornea; Goldmann applanation tonometry; Non-contact tonometry; Retrospective analysis; Ultrasound pachymetry