title: Recurrent lipomatous tumor of hypopharynx: case report and literature review.
abstract: Liposarcoma is one of the most common soft-tissue sarcomas in adults, but head and neck are rarely involved, especially regions of the larynx and hypopharynx. According to Enzinger and Weiss, liposarcoma can be divided into 5 subtypes: well-differentiated, myxoid, round cell, pleomorphic and dedifferentiated. We present an unusual case of well-differentiated liposarcoma of the hypopharynx in a patient with previous three procedures of endoscopic removal of hypopharyngeal tumor classified as benign lipoma. Well-differentiated liposarcoma is a tumor of low-grade malignancy, which frequently recurs locally, but does not metastasize. Wide tumor resection with free margins is mandatory. Immunohistochemistry is a useful diagnostic tool. We also discuss recently published literature on this unusual presentation of well-differentiated liposarcoma.
authors.forename: Jelena
authors.initials: J
authors.lastname: Sotirović
authors.forename: Biserka
authors.initials: B
authors.lastname: Vukomanović-Djurdjević
authors.forename: Nenad
authors.initials: N
authors.lastname: Baletić
authors.forename: Ljubomir
authors.initials: L
authors.lastname: Pavićević
authors.forename: Dušan
authors.initials: D
authors.lastname: Bijelić
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Perić
mesh_terms: D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D008080:Liposarcoma / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome