title: [Effective tocolysis without β-agonists].
abstract: Many years the β-mimetics (Partussisten, Gynipral) were first line tocolytic agents in terms of delaying premature delivery in our country. As these medicaments have been withdrawn from the pharmacy network, some concerns began to appear among our colleges considering the administration of other tocolytics and their effectiveness. Our goal is to compare the efficacy of other tocolytics with β-mimetics. That is why we reviewed the structure of premature deliveries in the University Hospital "Stoyan Kirkovich", Stara Zagora for two periods: 01.01.2013 - 31.12. 2013 and 01.01.2014 - 01.06.2014.
  
  
  RESULTS
  45 of 326 pregnancies (13.8%) > 20 weeks of gestation for 2013, treated with Gynipral have ended with a premature delivery vs. 13 of 110 pregnancies (11.8%), treated with magnesium (Mg SO4, Magnerich, Magnerot), calcium channel blockers and spasmolyticsfor the period - 01:01.2014 - 01.06.2014.
  
  
  CONCLUSIONS
  The results show, that at this stage, several months after the cessation of use of β-mimetics, there is no rise of number and percentage of premature deliveries, but there is even a tendence of decline. Larger periods and greater number of cases are needed to formulate conclusions with greater significance.
authors.forename: N
authors.initials: N
authors.lastname: Lazarov
authors.forename: L
authors.initials: L
authors.lastname: Lazarov
authors.forename: S
authors.initials: S
authors.lastname: Lazarov
mesh_terms: D058666:Adrenergic beta-2 Receptor Agonists / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D005260:Female; D006594:Hexoprenaline / Q000627:therapeutic use*; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use*; D007752:Obstetric Labor, Premature / Q000188:drug therapy*; D010276:Parasympatholytics / Q000627:therapeutic use*; D011247:Pregnancy; D015145:Tocolysis / Q000379:methods; D015149:Tocolytic Agents / Q000627:therapeutic use*
chemical_list: D058666:Adrenergic beta-2 Receptor Agonists; D002121:Calcium Channel Blockers; D010276:Parasympatholytics; D015149:Tocolytic Agents; D006594:Hexoprenaline; D008274:Magnesium