title: Clinical and laboratory measures associated with health-related quality of life in individuals with chronic ankle instability.
abstract: OBJECTIVE
  To identify clinician and laboratory-oriented measures of function capable of explaining health-related quality of life in individuals with chronic ankle instability.
  
  
  METHODS
  Cross-sectional.
  
  
  METHODS
  Laboratory.
  
  
  METHODS
  Forty physically active individuals with chronic ankle instability attended a single testing session.
  
  
  METHODS
  Participants completed health-related quality of life, postural control, strength, sensory, and mechanical assessments. Health-related quality of life assessments included the Short Form-12 Physical and Mental Summary Components, Disablement in the Physically Active Scale, Fear-Avoidance Beliefs Questionnaire, and the Foot and Ankle Ability Measure.
  
  
  RESULTS
  A combination of mechanical and functional impairments accounted for 18-35% of the variance associated with health-related quality of life related to physical function and fear. Although physical impairments accounted for 7% of the variance associated with mental health-related quality of life, the overall model was associated with a weak effect size.
  
  
  CONCLUSIONS
  Measures of postural control, dorsiflexion range of motion, plantar cutaneous sensation, and ankle arthrometry contributed to a significant proportion of the variance associated with health-related quality of life in those with chronic ankle instability. Other variables should be examined to address mental components of health-related quality of life.
authors.affiliation: Arizona School of Health Sciences, A.T. Still University, Mesa, AZ, USA. Electronic address: mnhouston@atsu.edu.
authors.forename: Megan N
authors.initials: MN
authors.lastname: Houston
authors.affiliation: School of Physical Therapy & Athletic Training, Old Dominion University, Norfolk, VA, USA. Electronic address: jhoch@odu.edu.
authors.forename: Johanna M
authors.initials: JM
authors.lastname: Hoch
authors.affiliation: The Steadman Clinic, Vail, CO, USA. Electronic address: mgabriner@thesteadmanclinic.com.
authors.forename: Michael L
authors.initials: ML
authors.lastname: Gabriner
authors.affiliation: School of Physical Education, Sport, and Exercise Science, Ball State University, Muncie, IN, USA. Electronic address: jlkirby@bsu.edu.
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Kirby
authors.affiliation: School of Physical Therapy & Athletic Training, Old Dominion University, Norfolk, VA, USA. Electronic address: mhoch@odu.edu.
authors.forename: Matthew C
authors.initials: MC
authors.lastname: Hoch
mesh_terms: D016512:Ankle Injuries / Q000503:physiopathology* / Q000523:psychology*; D001696:Biomechanical Phenomena; D002908:Chronic Disease; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D007593:Joint Instability / Q000503:physiopathology* / Q000523:psychology*; D008297:Male; D053580:Muscle Strength / Q000502:physiology; D011187:Posture / Q000502:physiology; D011788:Quality of Life; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Chronic ankle instability; Health-related quality of life; Patient-reported outcomes