title: Copper-catalyzed O-arylation of N-protected 1,2-aminoalcohols using functionalized trivalent organobismuth reagents.
abstract: The O-arylation of 1,2-aminoalcohols using functionalized triarylbismuth reagents is reported. The reaction can be performed using substoichiometric amounts of copper acetate and operates under mild conditions. Good functional group tolerance is observed, giving access to a range of β-aryloxyamines. The effect provided by the amino group in the arylation reaction is investigated.
authors.affiliation: Département de chimie, Université du Québec à Montréal, C.P. 8888, Succ. Centre-Ville, Montréal, Québec, Canada H3C 3P8. gagnon.alexandre@uqam.ca.
authors.forename: Pauline
authors.initials: P
authors.lastname: Petiot
authors.forename: Julien
authors.initials: J
authors.lastname: Dansereau
authors.forename: Martin
authors.initials: M
authors.lastname: Hébert
authors.forename: Imene
authors.initials: I
authors.lastname: Khene
authors.forename: Tabinda
authors.initials: T
authors.lastname: Ahmad
authors.forename: Samira
authors.initials: S
authors.lastname: Samaali
authors.forename: Maxime
authors.initials: M
authors.lastname: Leroy
authors.forename: Francis
authors.initials: F
authors.lastname: Pinsonneault
authors.forename: Claude Y
authors.initials: CY
authors.lastname: Legault
authors.forename: Alexandre
authors.initials: A
authors.lastname: Gagnon
mesh_terms: D000605:Amino Alcohols / Q000737:chemistry*; D001729:Bismuth / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*
chemical_list: D000605:Amino Alcohols; D007202:Indicators and Reagents; D009942:Organometallic Compounds; D003300:Copper; D009584:Nitrogen; D010100:Oxygen; D001729:Bismuth