title: The influence of body mass index on survival in breast cancer patients.
abstract: BACKGROUND
  More than half of breast cancer survivors (BCSs) are obese at diagnosis and experience approximately 50% to 96% of weight gain during treatment that could physically affect their survival. The aim of the study was to evaluate the influence of body mass index (BMI) on physical, anthropometric, and physiological parameters in BCSs.
  
  
  METHODS
  A cross-sectional study was conducted with 147 BCSs. Health-related fitness, anthropometric measures, cardiovascular state, and cancer-related fatigue (CRF) were assessed for our analysis and 3 groups were formed.
  
  
  RESULTS
  Tests of force handgrip (affected side: F = 3.44; P < .05; nonaffected side: F = 3.067; P < .05), functional capacity (F = 3.239; P = .043), and endurance of trunk flexors (×2 = 8.264; P = .016) were significantly lower in obese BCSs compared with the normal-weight group, whereas systolic (F = 5.839; P = .004) and diastolic blood pressure (F = 8.794; P < .001), waist circumference (F = 85.81; P < .001), and arm circumference at 10 cm (affected side: F = 23.530; P < .001; nonaffected side: F = 17.095; P < .001) and 5 cm (affected side: F = 21.751; P < .001; nonaffected side: F = 22.490; P < .001) were significantly greater in BCSs with higher BMI compared with other groups. No significant differences were observed between groups regarding lower limb endurance, resting heart rate or CRF.
  
  
  CONCLUSIONS
  This study demonstrated the influence of obesity on health-related fitness, anthropometric measures, and cardiovascular state.
authors.affiliation: Department of Physiotherapy, Faculty of Health Sciencies, University of Granada, Granada, Spain. Electronic address: irenecantarero@ugr.es.
authors.forename: Irene
authors.initials: I
authors.lastname: Cantarero-Villanueva
authors.affiliation: Department of Physiotherapy, Faculty of Health Sciencies, University of Granada, Granada, Spain.
authors.forename: Noelia
authors.initials: N
authors.lastname: Galiano-Castillo
authors.affiliation: Department of Physiotherapy, Faculty of Health Sciencies, University of Granada, Granada, Spain.
authors.forename: Carolina
authors.initials: C
authors.lastname: Fernández-Lao
authors.affiliation: Department of Physiotherapy, Faculty of Health Sciencies, University of Granada, Granada, Spain.
authors.forename: Lourdes
authors.initials: L
authors.lastname: Diaz-Rodríguez
authors.affiliation: Department of Physiotherapy, Faculty of Health Sciencies, University of Granada, Granada, Spain.
authors.forename: Antonio Manuel
authors.initials: AM
authors.lastname: Fernández-Pérez
authors.affiliation: Department of Physiotherapy, Faculty of Health Sciencies, University of Granada, Granada, Spain.
authors.forename: María J
authors.initials: MJ
authors.lastname: Sánchez
authors.affiliation: Department of Physiotherapy, Faculty of Health Sciencies, University of Granada, Granada, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Arroyo-Morales
mesh_terms: D000328:Adult; D015992:Body Mass Index; D001943:Breast Neoplasms / Q000150:complications / Q000401:mortality*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000150:complications; D010809:Physical Fitness
keywords: Cancer survivor; Comorbid condition; Obesity; Weigth gain