title: [Lines of research in the treatment of HIV infection].
abstract: Antiretroviral treatment have completely modified the face of HIV infection. Research of new therapeutic approaches during infection focus on the use of antiretroviral drugs and on new targets, treatment of immune activation and viral eradication. Recommendations for c-ART initiation are now broader. Future development in the area of antiretroviral therapy concern their use for prevention and the design of long-acting drugs. Extensive research efforts have led to the proposal of strategies that aim to treat immune activation which favor the occurrence of non AIDS defining disease and to eradicate HIV through the use of several different strategies (therapeutic vaccines, anti latency compounds). Results of these new approaches remain preliminary and antiretroviral treatment remain the only weapon to fight HIV infection.
authors.forename: Maryline
authors.initials: M
authors.lastname: Saidani
authors.forename: Jean-Daniel
authors.initials: JD
authors.lastname: Lelièvre
mesh_terms: D035843:Biomedical Research; D060740:Disease Eradication; D015658:HIV Infections / Q000188:drug therapy* / Q000517:prevention & control; D006801:Humans