title: Spectral Domain OCT Imaging Techniques in Tamoxifen Retinopathy.
abstract: OBJECTIVE
  To highlight the use of high-density spectral domain optical coherence tomography (SD-OCT) in the detection of tamoxifen retinopathy.
  
  
  METHODS
  An 82-year-old asymptomatic woman with a history of tamoxifen therapy for breast cancer was found to have bilateral refractile retinal deposits on fundus examination. Detection on SD-OCT was compared across imaging techniques. High-density SD-OCT demonstrated hyperreflective deposits in the inner retinal layers of each eye consistent with the diagnosis of tamoxifen retinopathy.
  
  
  CONCLUSIONS
  The optimal SD-OCT scan technique depends on the ocular condition being imaged. High-density scan techniques require longer acquisition time but may enhance the detection of focal retinal pathology.
authors.affiliation: *OD, FAAO †OD, PhD, FAAO Midwestern University, Arizona College of Optometry, Glendale, Arizona (both authors).
authors.forename: Jessica
authors.initials: J
authors.lastname: Neuville
authors.forename: Vladimir
authors.initials: V
authors.lastname: Yevseyenkov
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D005260:Female; D006801:Humans; D012160:Retina / Q000187:drug effects / Q000473:pathology*; D012164:Retinal Diseases / Q000139:chemically induced / Q000175:diagnosis*; D020845:Selective Estrogen Receptor Modulators / Q000009:adverse effects*; D013629:Tamoxifen / Q000009:adverse effects*; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity
chemical_list: D018931:Antineoplastic Agents, Hormonal; D020845:Selective Estrogen Receptor Modulators; D013629:Tamoxifen