title: Synthesis of a new class of Betti bases by the Mannich-type reaction: efficient, facile, solvent-free and one-pot protocol.
abstract: A variety of organocatalysts has been screened for the synthesis of arylaminonaphthols. It has been shown that (N,N-dimethylethanolamine) is a highly efficient organocatalyst for the direct synthesis of a novel class of arylaminonaphthols via three-component condensation of 2-naphthol, aldehydes, and arylamines under solvent-free conditions. Mild, one-pot, and green reaction conditions, relatively short reaction times and good yields make this protocol highly significant. 25 new compounds have been synthesized by this method.
authors.affiliation: Department of Organic and Biochemistry, Faculty of Chemistry, University of Tabriz, 5166614766, Tabriz, Iran, ashahrisa@yahoo.com.
authors.forename: Aziz
authors.initials: A
authors.lastname: Shahrisa
authors.forename: Reza
authors.initials: R
authors.lastname: Teimuri-Mofrad
authors.forename: Mahdi
authors.initials: M
authors.lastname: Gholamhosseini-Nazari
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D003642:Deanol / Q000737:chemistry*; D008958:Models, Molecular; D009284:Naphthols / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D000588:Amines; D009284:Naphthols; D003642:Deanol