title: Cu-Catalyzed selective C3-formylation of imidazo[1,2-a]pyridine C-H bonds with DMSO using molecular oxygen.
abstract: Using the widely available DMSO as the formylation reagent under oxidative conditions, an efficient Cu-catalyzed C3-formylation reaction of imidazo[1,2-a]pyridine C-H bonds to directly generate structurally sophisticated 3-formyl imidazo[1,2-a]pyridine derivatives has been developed. The reaction proceeded to generate products in good yields, and used the environmentally friendly molecular oxygen as the oxidant.
authors.affiliation: School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan 528458, P.R. China. caohua@gdpu.edu.cn.
authors.forename: Hua
authors.initials: H
authors.lastname: Cao
authors.forename: Sai
authors.initials: S
authors.lastname: Lei
authors.forename: Naiying
authors.initials: N
authors.lastname: Li
authors.forename: Longbin
authors.initials: L
authors.lastname: Chen
authors.forename: Jingyun
authors.initials: J
authors.lastname: Liu
authors.forename: Huiyin
authors.initials: H
authors.lastname: Cai
authors.forename: Shuxian
authors.initials: S
authors.lastname: Qiu
authors.forename: Jingwen
authors.initials: J
authors.lastname: Tan
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D006860:Hydrogen Bonding; D007093:Imidazoles / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007093:Imidazoles; D011725:Pyridines; D003300:Copper; D010100:Oxygen; D004121:Dimethyl Sulfoxide