title: Finger and toenail onycholysis.
abstract: Onycholysis - the separation of the nail plate from the nail bed occurs in fingers and toenails. It is diagnosed by the whitish appearance of the separated nail plate from the nail bed. In fingers, the majority is caused by trauma, manicuring, occupational or self-induced behavior. The most common disease producing fingernail onycholysis is psoriasis and pustular psoriasis. Phototoxic dermatitis, due to drugs can also produce finger onycholysis. Once the separation occurs, the environmental flora sets up temporary colonization in the available space. Finger onycholysis is most common in women. Candida albicans is often recovered from the onycholytic space. Many reports, want to associate the yeast as cause and effect, but the data are lacking and the treatment of the candida does not improve finger onycholysis. A reasonable explanation for the frequent isolation of Candida and Pseudomonas in fingernail onycholysis in women, is the close proximity the fingers have to the vaginal and gastrointestinal tract. Fifty per cent of humans harbour C. albicans in the GI tract and it is frequently carried to the vagina during hygienic practices. Finger onycholysis is best treated by drying the nail 'lytic' area with a hair blower, since all colonizing biota are moisture loving and perish in a dry environment. Toenail onycholysis has a very different etiology. It is mechanical, the result of pressure on the toes from the closed shoes, while walking, because of the ubiquitous uneven flat feet producing an asymmetric gait with more pressure on the foot with the flatter sole.
authors.affiliation: Dermatology Mt. Sinai Medical Center, Miami Beach, Florida.
authors.forename: N
authors.initials: N
authors.lastname: Zaias
authors.forename: S X
authors.initials: SX
authors.lastname: Escovar
authors.forename: M N
authors.initials: MN
authors.lastname: Zaiac
mesh_terms: D005385:Fingers; D005533:Foot Dermatoses / Q000209:etiology* / Q000628:therapy; D006229:Hand Dermatoses / Q000209:etiology* / Q000628:therapy; D006801:Humans; D054039:Onycholysis / Q000209:etiology* / Q000628:therapy*; D014009:Onychomycosis / Q000382:microbiology* / Q000628:therapy; D014034:Toes