title: Evaluation of safety and efficacy of transjugular liver biopsy in allogeneic hematopoietic stem cell transplant recipients.
abstract: We retrospectively evaluated the safety and utility of transjugular liver biopsy (TJLB) in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Ten patients underwent HSCT between 1991 and 2013. Eight patients with thrombocytopenia received platelet transfusions before and/or during TJLB. No complications associated with TJLB were observed. Samples adequate for a pathological diagnosis were obtained in 9 of the 10 patients, and the diagnoses made by TJLB were graft-versus-host-disease in eight patients and non-specific hepatitis in one. These results suggest that TJLB is a safe and effective procedure for the evaluation of liver injury in HSCT recipients.
authors.affiliation: Division of Hematology, Department of Medicine, Keio University School of Medicine.
authors.forename: Taku
authors.initials: T
authors.lastname: Kikuchi
authors.forename: Takehiko
authors.initials: T
authors.lastname: Mori
authors.forename: Yuya
authors.initials: Y
authors.lastname: Koda
authors.forename: Masuho
authors.initials: M
authors.lastname: Saburi
authors.forename: Sumiko
authors.initials: S
authors.lastname: Kohashi
authors.forename: Takaaki
authors.initials: T
authors.lastname: Toyama
authors.forename: Jun
authors.initials: J
authors.lastname: Kato
authors.forename: Subaru
authors.initials: S
authors.lastname: Hashimoto
authors.forename: Masayuki
authors.initials: M
authors.lastname: Nakatsuka
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Ebinuma
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Okamoto
mesh_terms: D000328:Adult; D064591:Allografts; D001707:Biopsy, Needle / Q000379:methods*; D005260:Female; D006086:Graft vs Host Disease / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006505:Hepatitis / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods*; D007601:Jugular Veins; D008107:Liver Diseases / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012449:Safety; D019172:Transplantation Conditioning / Q000009:adverse effects