title: Oesophageal flap valvuloplasty and wrapping suturing prevent gastrooesophageal reflux disease in dogs after oesophageal anastomosis.
abstract: OBJECTIVE
  To examine the efficiency of oesophageal flap valvuloplasty and wrapping suturing technique in decreasing the rate of postoperative gastrooesophageal reflux disease in a dog model.
  
  
  METHODS
  We operated on 10 dogs in this study. First, we resected a 5-cm portion of the distal oesophagus and then restored the continuity of the oesophageal and gastric walls by end-to-end anastomosis. A group of five dogs was subjected to the oesophageal flap valvuloplasty and wrapping suturing technique, whereas another group (control) of five dogs was subjected to the stapling technique after oesophagectomy. The symptom of gastrooesophageal reflux was recorded by 24-h pH oesophageal monitoring. Endoscopy and barium swallow examination were performed on all dogs. Anastomotic leakage was observed by X-ray imaging, whereas benign anastomotic stricture and mucosal damage were observed by endoscopy.
  
  
  RESULTS
  None of the 10 dogs experienced anastomotic leakage after oesophagectomy. Four dogs in the new technology group resumed regular feeding, whereas only two of the dogs in the control group tolerated solid food intake. pH monitoring demonstrated that 25% of the dogs in the experimental group exhibited reflux and that none had mucosal damage consistent with reflux. Conversely, both reflux and mucosal damage were observed in all dogs in the control group.
  
  
  CONCLUSIONS
  The oesophageal flap valvuloplasty and wrapping suturing technique can improve the postoperative quality of life through the long-term elimination of reflux oesophagitis and decreased stricture formation after primary oesophageal anastomosis.
authors.affiliation: Ji-Gang Dai, Quan-Xing Liu, Xu-Feng Deng, Jia-Xin Min, Department of Thoracic Surgery, Xinqiao Hospital, the Third Military Medical University, Chongqing 400037, China.
authors.forename: Ji-Gang
authors.initials: JG
authors.lastname: Dai
authors.affiliation: Ji-Gang Dai, Quan-Xing Liu, Xu-Feng Deng, Jia-Xin Min, Department of Thoracic Surgery, Xinqiao Hospital, the Third Military Medical University, Chongqing 400037, China.
authors.forename: Quan-Xing
authors.initials: QX
authors.lastname: Liu
authors.affiliation: Ji-Gang Dai, Quan-Xing Liu, Xu-Feng Deng, Jia-Xin Min, Department of Thoracic Surgery, Xinqiao Hospital, the Third Military Medical University, Chongqing 400037, China.
authors.forename: Xu-Feng
authors.initials: XF
authors.lastname: Den
authors.affiliation: Ji-Gang Dai, Quan-Xing Liu, Xu-Feng Deng, Jia-Xin Min, Department of Thoracic Surgery, Xinqiao Hospital, the Third Military Medical University, Chongqing 400037, China.
authors.forename: Jia-Xin
authors.initials: JX
authors.lastname: Min
mesh_terms: D000714:Anastomosis, Surgical; D057868:Anastomotic Leak / Q000209:etiology / Q000517:prevention & control; D000818:Animals; D001466:Barium Sulfate; D016022:Case-Control Studies; D003287:Contrast Media; D004285:Dogs; D004940:Esophageal Stenosis / Q000209:etiology / Q000517:prevention & control; D050782:Esophageal pH Monitoring; D016629:Esophagectomy; D004945:Esophagoscopy; D004947:Esophagus / Q000601:surgery*; D018662:Fundoplication / Q000009:adverse effects / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D005774:Gastrostomy; D006801:Humans; D013524:Surgical Flaps / Q000009:adverse effects; D013536:Suture Techniques / Q000009:adverse effects; D013997:Time Factors
chemical_list: D003287:Contrast Media; D001466:Barium Sulfate
keywords: Gastrooesophageal reflux; Oesophageal anastomosis; Oesophagectomy