title: Comprehensive experiment-clinical biochemistry: determination of blood glucose and triglycerides in normal and diabetic rats.
abstract: For second year medical students, we redesigned an original laboratory experiment and developed a combined research-teaching clinical biochemistry experiment. Using an established diabetic rat model to detect blood glucose and triglycerides, the students participate in the entire experimental process, which is not normally experienced during a standard clinical biochemistry exercise. The students are not only exposed to techniques and equipment but are also inspired to think more about the biochemical mechanisms of diseases. When linked with lecture topics about the metabolism of carbohydrates and lipids, the students obtain a better understanding of the relevance of abnormal metabolism in relation to diseases. Such understanding provides a solid foundation for the medical students' future research and for other clinical applications.
authors.affiliation: Teaching Laboratory Center of Medicine and Life Science, Tongji University School of Medicine, Shanghai, China; Department of Biochemistry and Molecular Biology, Tongji University School of Medicine, Shanghai, China.
authors.forename: Li
authors.initials: L
authors.lastname: Jiao
authors.forename: Shi
authors.initials: S
authors.lastname: Xiujuan
authors.forename: Wang
authors.initials: W
authors.lastname: Juan
authors.forename: Jia
authors.initials: J
authors.lastname: Song
authors.forename: Xu
authors.initials: X
authors.lastname: Lei
authors.forename: Xu
authors.initials: X
authors.lastname: Guotong
authors.forename: Lu
authors.initials: L
authors.lastname: Lixia
mesh_terms: D000818:Animals; D001671:Biochemistry / Q000193:education*; D035843:Biomedical Research / Q000193:education*; D001786:Blood Glucose; D003920:Diabetes Mellitus / Q000097:blood; D006801:Humans; D051381:Rats; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D014280:Triglycerides
keywords: blood glucose; blood triglyceride; clinical biochemistry; diabetic rat; laboratory practice; streptozotocin