title: [Effect of acupuncture at pericardium points of amplitude of low frequency fluctuations of healthy people in resting state functional magnetic resonance imaging].
abstract: OBJECTIVE
  To observe the effect of acupuncture at the whole points of Hand Jueyin pericardium meridian on the amplitude of low frequency fluctuations (ALFF) of healthy people in resting state (R1) functional magnetic resonance imaging (fMRI).
  
  
  METHODS
  Totally 16 healthy subjects received structure scan of T1 and T2. Then two fMRI scans were conducted for each participant. fMRI included the resting-state scan (R1; the scanning time was 8 min 6 s), the stimulating-acupoint scan (AP; the scanning time was 8 min 6 s). fMRI data acquisition from structure scanning and function scanning were processed with format conversion and statistical analysis.
  
  
  RESULTS
  Under R1 state, brain regions with activated ALFF signals included bilateral superior frontal gyrus, medial frontal gyrus, middle occipital gyrus, precuneus, superior temporal gyrus, and cingulate gyrus. Under the AP state, brain regions with activated ALFF signals were bilateral superior frontal gyrus, medial frontal gyrus, middle temporal gyrus, left fusiform gyrus, precuneus, posterior cingulate, and declivis. Compared with R1 state, obvious difference of ALFF signal areas of the brain caused by acupuncture at pericardium were: bilateral cuneus, precuneus, left posterior cingulate gyrus, right middle occipital gyrus, and right occipital lingual gyrus.
  
  
  CONCLUSIONS
  Acupuncture at the whole points of Hand Jueyin pericardium meridian could significantly change inherent activity states of the cerebral cortex, especially in bilateral superior frontal gyrus, medial frontal gyrus, and precuneus.
authors.forename: You-long
authors.initials: YL
authors.lastname: Zhou
authors.forename: Hong-zhou
authors.initials: HZ
authors.lastname: Xu
authors.forename: Yan-li
authors.initials: YL
authors.lastname: Duan
authors.forename: Gang
authors.initials: G
authors.lastname: Zhang
authors.forename: Cheng-guo
authors.initials: CG
authors.lastname: Su
authors.forename: Yun-hu
authors.initials: YH
authors.lastname: Wu
authors.forename: Wei
authors.initials: W
authors.lastname: Xing
authors.forename: Xiang-yu
authors.initials: XY
authors.lastname: Jin
mesh_terms: D026881:Acupuncture; D015669:Acupuncture Points; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D005625:Frontal Lobe; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D010496:Pericardium