title: Prevalence and clinical features of coagulation syndrome after endoscopic submucosal dissection for colorectal neoplasms.
abstract: OBJECTIVE
  There are several published studies examining the major complications (bleeding and perforation) of colon endoscopic submucosal dissection (ESD). However, little is known about the other complications, such as post-ESD coagulation syndrome (CS). The aims of this study were to evaluate the prevalence and the clinical features of CS after colon ESD.
  
  
  METHODS
  There were 183 cases treated with ESD for either a colorectal laterally spreading tumor or a polypoid mass in Konkuk University Medical Center. There were 151 cases enrolled in this study after excluding patients with perforation, bleeding, nonlifting sign, or nonneoplastic lesions. Patients with a fever above 37.7 °C, abdominal pain, and localized tenderness after ESD without macro- or microperforation, regardless of the symptoms of peritoneal irritation, were deemed as showing post-colon ESD CS.
  
  
  RESULTS
  There were 151 cases enrolled in this study, and 13 patients (8.6 %) showed CS after colorectal ESD. There were no differences in the demographic and endoscopic characteristics between the patients with CS and those without CS. The mean hospitalization stay was 3.0 ± 0.3 days longer in the CS (+) group (6.9 ± 1.9 days) than that in the CS (-) group (3.9 ± 1.6 days) (p = 0.001). All patients with CS were treated with conservative, nonsurgical management, such as fasting and intravenous antibiotics.
  
  
  CONCLUSIONS
  The rate of post-ESD CS was less than 9 % in this study. Although CS occurred, all of the patients with CS showed a favorable progression within 1 week.
authors.affiliation: Department of Internal Medicine, Digestive Disease Center, Konkuk University School of Medicine, Konkuk University Medical Center, 120-1 Neungdong-ro, Hwayang-dong, Gwangjin-gu, Seoul, 143-729, Korea.
authors.forename: Mi Jin
authors.initials: MJ
authors.lastname: Hong
authors.forename: Jeong Hwan
authors.initials: JH
authors.lastname: Kim
authors.forename: Sun-Young
authors.initials: SY
authors.lastname: Lee
authors.forename: In-Kyung
authors.initials: IK
authors.lastname: Sung
authors.forename: Hyung Seok
authors.initials: HS
authors.lastname: Park
authors.forename: Chan Sup
authors.initials: CS
authors.lastname: Shim
mesh_terms: D000368:Aged; D001778:Blood Coagulation Disorders / Q000175:diagnosis* / Q000453:epidemiology* / Q000209:etiology; D003110:Colonic Neoplasms / Q000601:surgery*; D004210:Dissection / Q000009:adverse effects*; D004724:Endoscopy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000601:surgery*; D013577:Syndrome