title: Comparison of bond strength of self-etch adhesive to pulp chamber dentin after placement of calcium hydroxide and various antibiotic pastes.
abstract: OBJECTIVE
  The aim of this study was to evaluate the effect of calcium hydroxide, double antibiotic paste (DAP) and triple antibiotic paste (TAP) with minocycline, cefaclor and amoxicillin on the micro tensile bond strength (µTBS) of self-etch adhesive to pulp chamber dentin.
  
  
  METHODS
  Sixty mandibular first molars were cut horizontally and randomly divided into a control group and five experimental groups, which received an intra-canal dressing, as follows: calcium hydroxide, DAP, TAP with minocycline, TAP with cefaclor and TAP with amoxicillin. After storing the specimens for 4 weeks, the medicaments were removed by irrigation with 10 mL each of the following solution: 2.5% NaOCl, 17% EDTA and distilled water. A self-etch adhesive (Clearfil S3 Bond, Okayama, Japan) was applied and composite resin (Clearfil Majesty Posterior, Kuraray Medical Inc., Japan) was placed into the cavity. A µTBS test was performed on each specimen using a universal test machine.
  
  
  RESULTS
  The DAP reduced the µTBS of self-etch adhesive compared to the control group, calcium hydroxide and TAP with minocycline and with cefaclor (p < 0.05). However, the other medicaments did not result in a decreased µTBS of self-etch adhesive to pulp chamber dentin as compared to the control group (p > 0.05).
  
  
  CONCLUSIONS
  The use of DAP resulted in a reduced µTBS of self-etch adhesive to pulp chamber dentin.
authors.affiliation: Department of Endodontics, Faculty of Dentistry, Atatürk University , Erzurum , Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Arslan
authors.forename: Merve
authors.initials: M
authors.lastname: Akcay
authors.forename: Mustafa
authors.initials: M
authors.lastname: Çakir
authors.forename: Adem
authors.initials: A
authors.lastname: Gok
authors.forename: Bilal
authors.initials: B
authors.lastname: Yasa
authors.forename: Mehmet
authors.initials: M
authors.lastname: Dalli
mesh_terms: D000658:Amoxicillin / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D002126:Calcium Hydroxide / Q000737:chemistry*; D002433:Cefaclor / Q000737:chemistry; D002939:Ciprofloxacin / Q000737:chemistry; D003188:Composite Resins / Q000737:chemistry; D001840:Dental Bonding; D003786:Dental Pulp Cavity / Q000648:ultrastructure*; D003799:Dental Stress Analysis; D003804:Dentin / Q000648:ultrastructure*; D017220:Dentin-Bonding Agents / Q000737:chemistry*; D004338:Drug Combinations; D004492:Edetic Acid / Q000737:chemistry; D006801:Humans; D008422:Materials Testing; D008795:Metronidazole / Q000737:chemistry; D008911:Minocycline / Q000737:chemistry; D011897:Random Allocation; D019279:Resin Cements / Q000737:chemistry; D012388:Root Canal Irrigants / Q000737:chemistry*; D012973:Sodium Hypochlorite / Q000737:chemistry; D013314:Stress, Mechanical; D013718:Tensile Strength
chemical_list: D000900:Anti-Bacterial Agents; C505694:Clearfil S3 Bond; D003188:Composite Resins; D017220:Dentin-Bonding Agents; D004338:Drug Combinations; D019279:Resin Cements; D012388:Root Canal Irrigants; C541508:clearfil majesty; D008795:Metronidazole; D002939:Ciprofloxacin; D002433:Cefaclor; D000658:Amoxicillin; D004492:Edetic Acid; D012973:Sodium Hypochlorite; D008911:Minocycline; D002126:Calcium Hydroxide
keywords: Adhesion; double antibiotic paste; micro tensile bond strength; minocycline; triple antibiotic paste