title: [Locomotive syndrome and metabolic syndrome].
abstract: The Japanese Orthopedic Association coined the term locomotive syndrome (LS) to designate a condition of elderly people in high risk groups of requiring nursing care because of problems with their musculoskeletal diseases. LS is a socioeconomic concept, and closely associated with osteoporosis, osteoarthritis, and sarcopenia. Recent studies have revealed that metabolic syndrome (MS), a clustering of cardiovascular risk factors, has been related with LS. For example, individuals with MS have a greater risk of osteoarthritis and sarcopenia. Secreted factors from adipose tissue and skeletal muscles, namely, adipokines and myokines, are involved in the association of LS and MS.
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Fukushi
authors.forename: Yukihide
authors.initials: Y
authors.lastname: Iwamoto
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D051346:Mobility Limitation; D009043:Motor Activity; D010003:Osteoarthritis / Q000150:complications; D010024:Osteoporosis / Q000150:complications; D055948:Sarcopenia / Q000150:complications; D013577:Syndrome