title: Multiparametric MRI-targeted TRUS prostate biopsies using visual registration.
abstract: Prebiopsy multiparametric prostate MRI (mp-MRI), followed by transrectal ultrasound-guided (TRUS-G) target biopsies (TB) of the prostate is a key combination for the diagnosis of clinically significant prostate cancers (CSPCa), to avoid prostate cancer (PCa) overtreatment. Several techniques are available for guiding TB to the suspicious mp-MRI targets, but the simplest, cheapest, and easiest to learn is "cognitive," with visual registration of MRI and TRUS data. This review details the successive steps of the method (target detection, mp-MRI reporting, intermodality fusion, TRUS guidance to target, sampling simulation, sampling, TRUS session reporting, and quality insurance), how to optimize each, and the global indications of mp-MRI-targeted biopsies. We discuss the diagnostic yield of visually-registered TB in comparison with conventional biopsy, and TB performed using other registration methods.
authors.affiliation: Department of Radiology, Lille University Hospital, Lille University, 59000 Lille, France ; Inserm U703, 59120 Loos, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Puech
authors.affiliation: Inserm U703, 59120 Loos, France ; Department of Urology, Lille University Hospital, Lille University, 59000 Lille, France.
authors.forename: Adil
authors.initials: A
authors.lastname: Ouzzane
authors.affiliation: Department of Radiology, Lille University Hospital, Lille University, 59000 Lille, France.
authors.forename: Vianney
authors.initials: V
authors.lastname: Gaillard
authors.affiliation: Inserm U703, 59120 Loos, France.
authors.forename: Nacim
authors.initials: N
authors.lastname: Betrouni
authors.affiliation: Department of Radiology, Lille University Hospital, Lille University, 59000 Lille, France.
authors.forename: Benoit
authors.initials: B
authors.lastname: Renard
authors.affiliation: Inserm U703, 59120 Loos, France ; Department of Urology, Lille University Hospital, Lille University, 59000 Lille, France.
authors.forename: Arnauld
authors.initials: A
authors.lastname: Villers
authors.affiliation: Department of Radiology, Lille University Hospital, Lille University, 59000 Lille, France ; Inserm U703, 59120 Loos, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Lemaitre
mesh_terms: D006801:Humans; D061705:Image-Guided Biopsy; D008279:Magnetic Resonance Imaging; D008297:Male; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D011859:Radiography