title: A new 1,6-benzoxazocine-5-one alkaloid isolated from the aerial parts of Peristrophe lanceolaria.
abstract: A new 1,6-benzoxazocine-5-one alkaloid has been isolated as its butyl acetal derivative (1) along with peristrophine from the n-BuOH and EtOAc fractions of the crude MeOH extract of the aerial parts of Peristrophe lanceolaria growing in Thailand. The structures of these compounds were elucidated on the basis of their spectroscopic data. These compounds were isolated for the first time from P. lanceolaria. The EtOAc and n-BuOH fractions also possessed significant antioxidant activity with IC50 values of 57 and 50 μg/mL, respectively (DPPH method), whereas 1 had an IC50 value of 23 μg/mL.
authors.forename: Wasana
authors.initials: W
authors.lastname: Prapalert
authors.forename: Dammrong
authors.initials: D
authors.lastname: Santiarworn
authors.forename: Saisunee
authors.initials: S
authors.lastname: Liawruangrath
authors.forename: Boonsom
authors.initials: B
authors.lastname: Liawruangrath
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Pyne
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry; D001713:Biphenyl Compounds / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry*; D010851:Picrates / Q000737:chemistry; D035261:Plant Components, Aerial / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D013785:Thailand
chemical_list: D000470:Alkaloids; D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D010851:Picrates; D010936:Plant Extracts; C004931:1,1-diphenyl-2-picrylhydrazyl