title: Looks can be deceiving: reconsidering the evidence for gliotransmission.
abstract: Gliotransmission, a process involving active vesicular release of glutamate and other neurotransmitters by astrocytes, is thought to play a critical role in many brain functions. A new paper by Nedergaard et al. (2014) identifies an experimental flaw in these previous studies suggesting that astrocytes may not perform active vesicular release after all.
authors.affiliation: Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305-5125, USA. Electronic address: ssloan1@stanford.edu.
authors.forename: Steven A
authors.initials: SA
authors.lastname: Sloan
authors.affiliation: Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305-5125, USA.
authors.forename: Ben A
authors.initials: BA
authors.lastname: Barres
mesh_terms: D000818:Animals; D005260:Female; D005786:Gene Expression Regulation; D008297:Male; D009474:Neurons / Q000378:metabolism*; D050600:SNARE Proteins / Q000096:biosynthesis*
chemical_list: D050600:SNARE Proteins