title: Testing for Partial RhD with a D-Screen Diagast Kit in Moroccan Blood Donors with Weak D Expression.
abstract: The aim of this study was to search for the partial D phenotype in Moroccan blood donors with weak D expression. The study included 32 samples with weak D phenotype, and partial D category red blood cells were detected with the D-Screen Diagast kit, which consists in 9 monoclonal anti-D antibodies specific for the most common categories of partial D. Among the 32 samples studied, we identified 13 specific reactions to a partial D antigen (3 DVI, 2 DVa, 2 DIII((a,b,c)), and 6 DVII), with 8 reactions suggesting a weak D and 11 reactions providing no formal argument in favor of a partial D antigen. This work can be used to validate the performance of the anti-D reagent and to improve the safety of transfusion of red blood cells from donors expressing the partial D antigen by integrating the finding into the recipient file with a recommendation concerning the appropriate care.
authors.affiliation: Centre National de Transfusion Sanguine, rue Lamfadel Cherkaoui, Madinat Al Irfane, P.O. Box 180, 10000 Rabat, Morocco ; Departement de Biologie, Faculté des Sciences, University MDV Rabat Agdal, 1014 Rabat, Morocco.
authors.forename: Z
authors.initials: Z
authors.lastname: Kabiri
authors.affiliation: Centre National de Transfusion Sanguine, rue Lamfadel Cherkaoui, Madinat Al Irfane, P.O. Box 180, 10000 Rabat, Morocco.
authors.forename: M
authors.initials: M
authors.lastname: Benajiba
authors.affiliation: Centre Regional de Transfusion Sanguine, rue Lamfadel Cherkaoui, Madinat Al Irfane, P.O. Box 180, 10000 Rabat, Morocco.
authors.forename: K
authors.initials: K
authors.lastname: Hajjout
authors.affiliation: Departement de Biologie, Faculté des Sciences, University MDV Rabat Agdal, 1014 Rabat, Morocco.
authors.forename: N
authors.initials: N
authors.lastname: Dakka
authors.affiliation: Departement de Biologie, Faculté des Sciences, University MDV Rabat Agdal, 1014 Rabat, Morocco.
authors.forename: H
authors.initials: H
authors.lastname: Bellaoui