title: Multiple minute digitate hyperkeratosis affecting the face and folds: clinical, dermoscopic, and histological report of a familial case.
abstract: A case of a generalized non-follicular digitate keratosis classified as multiple minute digitate hyperkeratosis is described with suggestive clinical, dermoscopic, and histopathogical data. The patient was a 52-year-old Caucasian woman presenting a 6-year history of multiple asymptomatic skin-colored digitate lesions, 3 to 5 mm long and 1 to 2 mm wide, distributed on the forehead, neck, and extensor surface of the arms as well as in the inframammary folds, axillae, and lower limbs, especially on the popliteal fold. She reported having a 67-year-old sister and a 39-year-old niece with an identical eruption. Treatment with 15% glycolic acid (AHA) lotion and heliotherapy improved this disturbing eruption.
authors.affiliation: Epidermis Dermatology Center, CUF Institute, Porto, Portugal. Faculty of Medicine, University of Porto, Porto, Portugal. Corresponding author: Corresponding author: epidermis@epidermis.pt.
authors.forename: Osvaldo
authors.initials: O
authors.lastname: Correia
authors.affiliation: Epidermis Dermatology Center, CUF Institute, Porto, Portugal.
authors.forename: Natividade
authors.initials: N
authors.lastname: Rocha
authors.affiliation: Epidermis Dermatology Center, CUF Institute, Porto, Portugal. Department of Dermatology, Inselspital, University of Bern, Bern, Switzerland.
authors.forename: Eckart
authors.initials: E
authors.lastname: Haneke
mesh_terms: D058070:Asymptomatic Diseases; D046169:Dermoscopy; D005145:Face; D005260:Female; D006016:Glycolates / Q000627:therapeutic use; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use*; D007642:Keratosis / Q000188:drug therapy / Q000235:genetics / Q000473:pathology*; D008875:Middle Aged
chemical_list: D006016:Glycolates; D007641:Keratolytic Agents; C031149:glycolic acid