title: [Analysis of risk factors associated with weaning from mechanical ventilation in critical patients with major abdominal surgery].
abstract: OBJECTIVE
  To analyze the risk factors involved in the weaning from mechanical ventilation in critical patients who underwent major abdominal surgery.
  
  
  METHODS
  This retrospective study was conducted at Department of Critical Care Medicine in Peking University People's Hospital. The subjects included all critical ill patients who underwent major abdominal surgery from January 2011 to December 2013. Clinical and laboratory parameters in perioperative period were investigated for the risk factors involved in the weaning from mechanical ventilation.
  
  
  RESULTS
  In this study, 381 patients were included, of whom, 274 were successfully weaned. We found old age, lower left ventricular ejection fraction (LVEF) before surgery, with the complication of myocardial injury after noncardiac surgery (MINS) and lower serum albumin level after surgery were the independent risk factors of weaning from mechanical ventilation. And the days of intensive care unit and 28-day mortality of patients who successfully weaned were better than patients who failed to wean.
  
  
  CONCLUSIONS
  Old age, lower LVEF before surgery, with the complication of MINS and lower serum albumin level after surgery were independent risk factors of weaning in critical patients who underwent major abdominal surgery.
authors.affiliation: Department of Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China.
authors.forename: S
authors.initials: S
authors.lastname: Li
authors.affiliation: Department of Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China.
authors.forename: Y Z
authors.initials: YZ
authors.lastname: An
authors.affiliation: Department of Cardiology, Peking University People's Hospital, Beijing 100044, China.
authors.forename: J Y
authors.initials: JY
authors.lastname: Ren
authors.affiliation: Department of Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China.
authors.forename: F X
authors.initials: FX
authors.lastname: Zhu
authors.affiliation: Department of Cardiology, Peking University People's Hospital, Beijing 100044, China.
authors.forename: H
authors.initials: H
authors.lastname: Chen
mesh_terms: D000367:Age Factors; D006801:Humans; D007362:Intensive Care Units; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012307:Risk Factors; D012709:Serum Albumin; D013514:Surgical Procedures, Operative; D013997:Time Factors; D015300:Ventilator Weaning; D016277:Ventricular Function, Left
chemical_list: D012709:Serum Albumin