title: Photocatalytic generation of N-centered hydrazonyl radicals: a strategy for hydroamination of β,γ-unsaturated hydrazones.
abstract: A visible-light photocatalytic generation of N-centered hydrazonyl radicals has been accomplished for the first time. This approach allows efficient intramolecular addition of hydrazonyl radical to terminal alkenes, thus providing hydroamination and oxyamination products in good yields. Importantly, the protocol involves deprotonation of an N-H bond and photocatalytic oxidation to an N-centered radical, thus obviating the need to prepare photolabile amine precursors or the stoichiometric use of oxidizing reagents.
authors.forename: Xiao-Qiang
authors.initials: XQ
authors.lastname: Hu
authors.forename: Jia-Rong
authors.initials: JR
authors.lastname: Chen
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wei
authors.forename: Feng-Lei
authors.initials: FL
authors.lastname: Liu
authors.forename: Qiao-Hui
authors.initials: QH
authors.lastname: Deng
authors.forename: André M
authors.initials: AM
authors.lastname: Beauchemin
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Xiao
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D005609:Free Radicals; D006835:Hydrazones / Q000737:chemistry*; D055668:Photochemical Processes
chemical_list: D000588:Amines; D005609:Free Radicals; D006835:Hydrazones