title: [Chronotropic properties of adaptogenic drugs].
abstract: Adaptogenic agents of hormonal (melatonin) and plant origin (ginseng and bilobil) produce optimizing effect on circadian rhythm of locomotion and on the temporal dynamics of forced swimming in intact and false-operated rats. Melatonin exhibits the most expressed impact on behavior of animals. After the removal of the pineal gland, these effects of investigated drugs were significantly decreased. It is suggested that the pineal gland may take part in the chronotropic activity of adaptogenic drugs.
authors.forename: É V
authors.initials: ÉV
authors.lastname: Beĭer
authors.forename: A A
authors.initials: AA
authors.lastname: Skorniakov
authors.forename: É B
authors.initials: ÉB
authors.lastname: Arushanian
mesh_terms: D000818:Animals; D021461:Animals, Outbred Strains; D001522:Behavior, Animal / Q000187:drug effects; D002940:Circadian Rhythm / Q000187:drug effects* / Q000502:physiology; D007103:Immobilization; D007274:Injections, Intraperitoneal; D008027:Light; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D005894:Panax / Q000737:chemistry; D010870:Pineal Gland / Q000187:drug effects* / Q000502:physiology / Q000601:surgery; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D012118:Resorcinols / Q000494:pharmacology*; D013550:Swimming
chemical_list: D010936:Plant Extracts; D012118:Resorcinols; C064011:bilobol; D008550:Melatonin