title: Primary angiomatoid melanoma as an exceptional morphologic pattern in cutaneous melanoma. A case report and review of the literature.
abstract: We report a case of angiomatoid melanoma on the right thigh of a 59-year-old man. The histologic growth pattern of the tumor mimicked vascular proliferation, and the cells lining the pseudovascular spaces were positive for protein S-100, HMB-45, and MITF-1. The differential diagnosis is with angiosarcoma and pseudovascular adenoid squamous cell carcinoma. The case we present is the fifth reported to date.
authors.affiliation: Departamento de Anatomía Patológica, Hospital Regional Lic. Adolfo López Mateos ISSSTE, México DF, México.
authors.forename: G
authors.initials: G
authors.lastname: Ramos-Rodríguez
authors.affiliation: Departamento de Patología Quirúrgica y Molecular, Centro Médico ABC, México DF, México; Departamento de Biología Celular y Tisular, Universidad Panamericana, México DF, México. Electronic address: cortiz@abchospital.com.
authors.forename: C
authors.initials: C
authors.lastname: Ortiz-Hidalgo
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis; D003937:Diagnosis, Differential; D006394:Hemangiosarcoma / Q000175:diagnosis; D006801:Humans; D008297:Male; D008545:Melanoma / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D058950:Melanoma-Specific Antigens / Q000032:analysis; D051739:Microphthalmia-Associated Transcription Factor / Q000032:analysis; D008875:Middle Aged; D008940:Mitotic Index; D009363:Neoplasm Proteins / Q000032:analysis; D009418:S100 Proteins / Q000032:analysis; D012878:Skin Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D058951:gp100 Melanoma Antigen
chemical_list: C497234:MITF protein, human; D058950:Melanoma-Specific Antigens; D051739:Microphthalmia-Associated Transcription Factor; D009363:Neoplasm Proteins; C548637:PMEL protein, human; D009418:S100 Proteins; D058951:gp100 Melanoma Antigen
keywords: Angiomatoid melanoma; Angiosarcoma; HMB-45; Human Melanoma Black-45 (HMB-45); Melanoma angiomatoide; Protein S-100; Proteína S-100