title: [Gastric vascular lesions in cirrhosis: gastropathy and antral vascular ectasia].
abstract: Portal hypertensive gastropathy (GHP) is a complication of portal hypertension usually associated with liver cirrhosis. The pathogenesis is unclear but the presence of portal hypertension is an essential factor for its development. GHP may be asymptomatic or present as gastrointestinal bleeding or iron deficiency anemia. Endoscopic lesions vary from a mosaic pattern to diffuse red spots; the most common location is the fundus. Treatment is indicated when there is acute or chronic bleeding, as secondary prophylaxis. There is insufficient evidence to recommend primary prophylaxis in patients who have never bled. Drugs that decrease portal pressure, such as non-cardioselective beta-blockers, and/or endoscopic ablative treatments, such as argon-beam coagulation, may be used. The role of transarterial intrahepatic portosystemic shunt) or bypass surgery has been insufficiently analyzed. Antral vascular ectasia (EVA) is a rare entity in liver cirrhosis, whose pathophysiology is still unknown. Clinical presentation is similar to that of GHP and endoscopy usually shows red spots in the antrum. Biopsy is often required to differentiate EVA from GHP. There is no effective medical therapy, so endoscopic ablative therapy and, in severe cases, antrectomy are recommended.
authors.affiliation: Servicio de Digestivo, Corporació Sanitària i Universitària Parc Taulí, Sabadell, España; Departament de Medicina, Universitat Autònoma de Barcelona, España. Electronic address: mcasasr@tauli.cat.
authors.forename: Meritxell
authors.initials: M
authors.lastname: Casas
authors.affiliation: Servicio de Digestivo, Corporació Sanitària i Universitària Parc Taulí, Sabadell, España; Departament de Medicina, Universitat Autònoma de Barcelona, España; Ciberhed, Instituo Carlos III, Madrid, España.
authors.forename: Xavier
authors.initials: X
authors.lastname: Calvet
authors.affiliation: Servicio de Digestivo, Corporació Sanitària i Universitària Parc Taulí, Sabadell, España; Departament de Medicina, Universitat Autònoma de Barcelona, España; Ciberhed, Instituo Carlos III, Madrid, España.
authors.forename: Mercedes
authors.initials: M
authors.lastname: Vergara
authors.affiliation: Servicio de Anatomía Patológica, Corporació Sanitària i Universitària Parc Taulí, Sabadell, España.
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Bella
authors.affiliation: Servicio de Digestivo, Corporació Sanitària i Universitària Parc Taulí, Sabadell, España; Departament de Medicina, Universitat Autònoma de Barcelona, España; Ciberhed, Instituo Carlos III, Madrid, España.
authors.forename: Félix
authors.initials: F
authors.lastname: Junquera
authors.affiliation: Servicio de Digestivo, Corporació Sanitària i Universitària Parc Taulí, Sabadell, España; Departament de Medicina, Universitat Autònoma de Barcelona, España.
authors.forename: Eva
authors.initials: E
authors.lastname: Martinez-Bauer
authors.affiliation: Servicio de Digestivo, Corporació Sanitària i Universitària Parc Taulí, Sabadell, España; Departament de Medicina, Universitat Autònoma de Barcelona, España; Ciberhed, Instituo Carlos III, Madrid, España.
authors.forename: Rafael
authors.initials: R
authors.lastname: Campo
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000209:etiology; D005743:Gastrectomy / Q000379:methods; D020252:Gastric Antral Vascular Ectasia / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D006471:Gastrointestinal Hemorrhage / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D005773:Gastroscopy; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications*; D008103:Liver Cirrhosis / Q000150:complications*; D011170:Portasystemic Shunt, Surgical
keywords: Anatomía patológica; Cirrosis hepática; Clasificación; Classification; Ectasia vascular antral; Gastric antral vascular ectasia; Gastropathy; Gastropatía; Hipertensión portal; Liver cirrosis; Pathology; Portal hipertension; Tratamiento; Treatment