title: Cylindroma: an update.
abstract: This paper reviews the recent literature on cylindroma, a rare tumor originating from the cutaneous adnexal structures of the scalp and face. Benign cylindroma is more frequent in women, and there are solitary and multiple forms, which are autosomal. Malignant cylindroma can occur in the Brooke-Spiegler syndrome, and malignant transformation is more frequent in multiple variants than in solitary tumors. Its histopathological basis is controversial, and its origin is unknown, although it is known that there is a genetic basis for onset of these tumors in Brooke-Spiegler syndrome.
authors.affiliation: Sectors of Dermatology, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Clarice
authors.initials: C
authors.lastname: Jordão
authors.forename: Taissa Canedo
authors.initials: TC
authors.lastname: de Magalhães
authors.forename: Tullia
authors.initials: T
authors.lastname: Cuzzi
authors.forename: Marcia
authors.initials: M
authors.lastname: Ramos-e-Silva
mesh_terms: D003528:Carcinoma, Adenoid Cystic / Q000235:genetics / Q000473:pathology*; D005153:Facial Neoplasms / Q000473:pathology*; D006801:Humans; D009386:Neoplastic Syndromes, Hereditary / Q000175:diagnosis* / Q000235:genetics; D012535:Scalp; D012878:Skin Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*