title: Tularemia in children, Turkey, September 2009-November 2012.
abstract: Tularemia, a zoonotic disease caused by Francisella tularensis, is found throughout most of the Northern Hemisphere. It is not well known and is often misdiagnosed in children. Our aim with this study was to evaluate the diagnosis, treatment, and prognosis for 100 children with tularemia in Turkey. The mean patient age was 10.1 ± 3.5 years (range 3-18 years), and most (63%) patients were male. The most common physical signs and laboratory findings were cervical lymphadenopathy (92%) and elevated erythrocyte sedimentation rate (89%). Treatment response was higher and rate of relapse lower for children 5-10 years of age than for those in other age groups. Associated with treatment failure were female sex, treatment delay of ≥16 days, and use of doxycycline. Tularemia is endemic to Turkey, and the number of cases has been increasing among children as well as adults.
authors.forename: Hasan
authors.initials: H
authors.lastname: Tezer
authors.forename: Aslınur
authors.initials: A
authors.lastname: Ozkaya-Parlakay
authors.forename: Hakan
authors.initials: H
authors.lastname: Aykan
authors.forename: Mustafa
authors.initials: M
authors.lastname: Erkocoglu
authors.forename: Belgin
authors.initials: B
authors.lastname: Gülhan
authors.forename: Ahmet
authors.initials: A
authors.lastname: Demir
authors.forename: Saliha
authors.initials: S
authors.lastname: Kanik-Yuksek
authors.forename: Anil
authors.initials: A
authors.lastname: Tapisiz
authors.forename: Meltem
authors.initials: M
authors.lastname: Polat
authors.forename: Soner
authors.initials: S
authors.lastname: Kara
authors.forename: Ilker
authors.initials: I
authors.lastname: Devrim
authors.forename: Selcuk
authors.initials: S
authors.lastname: Kilic
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012621:Seasons; D016896:Treatment Outcome; D014406:Tularemia / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D014421:Turkey / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents