title: Use of Treponema pallidum PCR in testing of ulcers for diagnosis of primary syphilis.
abstract: Treponema pallidum PCR (Tp-PCR) has been noted as a valid method for diagnosing syphilis. We compared Tp-PCR to a combination of darkfield microscopy (DFM), the reference method, and serologic testing in a cohort of 273 patients from France and Switzerland and found the diagnostic accuracy of Tp-PCR was higher than that for DFM.
authors.forename: Angèle
authors.initials: A
authors.lastname: Gayet-Ageron
authors.forename: Patrice
authors.initials: P
authors.lastname: Sednaoui
authors.forename: Stephan
authors.initials: S
authors.lastname: Lautenschlager
authors.forename: Tristan
authors.initials: T
authors.lastname: Ferry
authors.forename: Laurence
authors.initials: L
authors.lastname: Toutous-Trellu
authors.forename: Matthias
authors.initials: M
authors.lastname: Cavassini
authors.forename: Fatima
authors.initials: F
authors.lastname: Yassir
authors.forename: Begoña
authors.initials: B
authors.lastname: Martinez de Tejada
authors.forename: Stéphane
authors.initials: S
authors.lastname: Emonet
authors.forename: Christophe
authors.initials: C
authors.lastname: Combescure
authors.forename: Jacques
authors.initials: J
authors.lastname: Schrenzel
authors.forename: Thomas
authors.initials: T
authors.lastname: Perneger
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D025202:Molecular Diagnostic Techniques; D011446:Prospective Studies; D012883:Skin Ulcer / Q000175:diagnosis* / Q000382:microbiology; D013587:Syphilis / Q000175:diagnosis* / Q000382:microbiology; D014210:Treponema pallidum / Q000235:genetics*