title: N-heterocyclic carbene catalyzed highly chemoselective intermolecular crossed acyloin condensation of aromatic aldehydes with trifluoroacetaldehyde ethyl hemiacetal.
abstract: A highly chemoselective intermolecular crossed acyloin condensation between aromatic aldehydes and trifluoroacetaldehyde ethyl hemiacetal has been developed under mild reaction conditions using N-heterocyclic carbene as a catalyst. A wide range of aromatic aldehydes bearing electron-withdrawing and -donating substituents underwent a smooth transformation to their corresponding trifluoromethyl containing acyloin derivatives in moderate to good yields.
authors.affiliation: Department of Chemical Sciences, Indian Institute of Science Education and Research (IISER) Mohali , Sector 81, Knowledge City, S. A. S. Nagar, Manauli (PO), Punjab - 140306, India.
authors.forename: Bandaru T
authors.initials: BT
authors.lastname: Ramanjaneyulu
authors.forename: Sriram
authors.initials: S
authors.lastname: Mahesh
authors.forename: Ramasamy
authors.initials: R
authors.lastname: Vijaya Anand