title: Long-term vocal outcomes of refined nerve-muscle pedicle flap implantation combined with arytenoid adduction.
abstract: The objective of this study is to evaluate long-term efficacy of refined nerve-muscle pedicle (NMP) flap implantation combined with arytenoid adduction (AA) for treatment of unilateral vocal fold paralysis (UVFP). The authors retrospectively reviewed 33 patients with UVFP who received refined NMP flap implantation with AA and were followed up over a 1-year period. Evaluation of vocal fold vibration (regularity, amplitude, and glottal gap), aerodynamic analysis (maximum phonation time [MPT] and mean airflow rate [MFR]), and perceptual evaluation (Grade and Breathiness) were performed preoperatively and at five different time points (1, 3, 6, 12, and 24 months) postoperatively. All voice parameters improved significantly postoperatively. All parameters except MFR also continued to improve over the course of 24 months. In the videostroboscopic analysis, the parameter for regularity 24 months after surgery was significantly improved compared with that at 1, 3, and 6 months after surgery. There were also significant improvements in amplitude and the glottal gap 24 months after surgery in comparison with values at 3 and 6 months after surgery and 3 months after surgery, respectively. Significant improvement in aerodynamic and perceptual measurements during the follow-up period together with near-normal vocal fold vibration was achieved by delayed reinnervation with refined NMP flap implantation and AA. The combined surgical technique is effective in the treatment of severe breathy dysphonia due to UVFP. Level of evidence 4.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Kumamoto University Graduate School of Medicine, Honjyo, Kumamoto, 860-8556, Japan, hurukiyokizidainootoko@yahoo.co.jp.
authors.forename: Narihiro
authors.initials: N
authors.lastname: Kodama
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Sanuki
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Kumai
authors.forename: Eiji
authors.initials: E
authors.lastname: Yumoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001193:Arytenoid Cartilage / Q000601:surgery*; D002572:Cervical Plexus; D055154:Dysphonia / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009334:Neck Muscles / Q000637:transplantation; D010699:Phonation; D012189:Retrospective Studies; D049489:Stroboscopy; D013524:Surgical Flaps / Q000294:innervation; D014741:Video Recording; D014826:Vocal Cord Paralysis / Q000601:surgery*