title: Invasive mucinous adenocarcinoma mimicking organizing pneumonia associated with Mycobacterium fortuitum infection.
abstract: We herein report the case of a 68-year-old man diagnosed with invasive mucinous adenocarcinoma of the lungs. Chest computed tomography showed subpleural ground-glass opacity and small nodules with cavitation. A culture of the bronchoalveolar lavage fluid resulted in the detection of Mycobacterium fortuitum. The patient's lung consolidation rapidly progressed; however, repeated bronchoscopy showed no atypical cells, thus suggesting a diagnosis of organizing pneumonia associated with M. fortuitum infection. However, the surgical biopsy specimen was diagnostic for adenocarcinoma, with no mycobacterial infection. Invasive mucinous adenocarcinoma should not be excluded in the differential diagnosis of patients with clinical features of organizing pneumonia and nontuberculous mycobacterium infection, even if a transbronchial biopsy confirms the absence of malignancy.
authors.affiliation: Department of Allergy and Respiratory Medicine, Okayama University Hospital, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Morichika
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Miyahara
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Hotta
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Okamoto
authors.forename: Daisuke
authors.initials: D
authors.lastname: Minami
authors.forename: Masahiro
authors.initials: M
authors.lastname: Irie
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Tanimoto
authors.forename: Arihiko
authors.initials: A
authors.lastname: Kanehiro
authors.forename: Mitsune
authors.initials: M
authors.lastname: Tanimoto
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Kiura
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D000368:Aged; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D001999:Bronchoscopy / Q000379:methods; D003937:Diagnosis, Differential; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000382:microbiology*; D019907:Mycobacterium fortuitum / Q000302:isolation & purification*; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000382:microbiology*