title: Immune escape mechanisms as a guide for cancer immunotherapy.
abstract: Immunotherapy has demonstrated impressive outcomes for some patients with cancer. However, selecting patients who are most likely to respond to immunotherapy remains a clinical challenge. Here, we discuss immune escape mechanisms exploited by cancer and present strategies for applying this knowledge to improving the efficacy of cancer immunotherapy.
authors.affiliation: Abramson Cancer Center, Department of Medicine, Division of Hematology-Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania. gregory.beatty@uphs.upenn.edu.
authors.forename: Gregory L
authors.initials: GL
authors.lastname: Beatty
authors.affiliation: Abramson Cancer Center, Department of Medicine, Division of Hematology-Oncology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
authors.forename: Whitney L
authors.initials: WL
authors.lastname: Gladney
mesh_terms: D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D009369:Neoplasms / Q000276:immunology* / Q000628:therapy*; D019139:Tumor Escape / Q000276:immunology*