title: Angioplasty for renovascular hypertension in 78 children.
abstract: OBJECTIVE
  To evaluate the outcome of percutaneous transluminal angioplasty (PTA) in children with renovascular hypertension (RVH) treated at a single centre over 29 years.
  
  
  METHODS
  A retrospective study of the medical charts of all children with RVH who underwent PTA between 1984 and 2012. The primary outcome measurement was blood pressure (BP) achieved after the procedure. The BP before the procedure was compared with that at last available follow-up, 6 (range 0.6-16) years after the initial procedure.
  
  
  RESULTS
  Seventy-eight children with median (range) age of 6.5 (0.5-17) years were studied. Twenty-three (29.5%) had an underlying syndrome, 35 (44.9%) children had bilateral renal artery stenosis (RAS), 18 (23%) intrarenal disease and 11(14%) showed bilateral RAS and intrarenal disease. Twenty (25.6%) children had mid-aortic syndrome and 14 (17.9%) cerebrovascular disease. One hundred and fourteen PTA procedures were carried out including 31 stent insertions. Following PTA, BP was improved in 49 (62.8%) children and of those 18 (23.1%) were cured. Children with involvement of only the main renal arteries showed improved BP control in 79.9% of the children with cure in 39.5%. BP was intentionally maintained above the 95th centile for age and height in four children with coexistent cerebrovascular disease. No change in BP was seen in 18 children despite observed technical success of the PTA, and in seven children due to technical failure of the procedure.
  
  
  CONCLUSIONS
  PTA provided a clinical benefit in 62.8% of children with RVH.
authors.affiliation: Department of Paediatrics, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: Jameela A
authors.initials: JA
authors.lastname: Kari
authors.affiliation: Department of Radiology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: Derek J
authors.initials: DJ
authors.lastname: Roebuck
authors.affiliation: Department of Radiology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: Clare A
authors.initials: CA
authors.lastname: McLaren
authors.affiliation: Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: Meryl
authors.initials: M
authors.lastname: Davis
authors.affiliation: Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Dillon
authors.affiliation: Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: George
authors.initials: G
authors.lastname: Hamilton
authors.affiliation: Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: Rukshana
authors.initials: R
authors.lastname: Shroff
authors.affiliation: Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Marks
authors.affiliation: Department of Paediatric Nephrology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: Kjell
authors.initials: K
authors.lastname: Tullus
mesh_terms: D000293:Adolescent; D000792:Angiography; D017130:Angioplasty / Q000009:adverse effects / Q000379:methods*; D001794:Blood Pressure; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006978:Hypertension, Renovascular / Q000601:surgery*; D007223:Infant; D008297:Male; D011183:Postoperative Complications; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: Imaging; Nephrology