title: Two decades of voluntary nonremunerated blood donation in Shenzhen, China.
abstract: BACKGROUND
  As an emerging metropolis with population expansion from 2 million to 10 million from 1993 to 2012, the clinical demand for blood in Shenzhen has increased 20 times. To deal with this big challenge, Shenzhen utilized voluntary nonremunerated blood donation (VNRBD) in 1993 for the first time in China. After two decades of efforts, Shenzhen has achieved self-sufficiency in its blood supply and guaranteed its blood security by nonpaid blood donation.
  
  
  METHODS
  We summarized the strategies to achieve self-sufficiency and security in the blood supply in Shenzhen during two decades, including the legal construction of VNRBDs and the continuously improving strategies to recruit and retain nonpaid donors. The collection data of whole blood (WB) and apheresis platelet (PLT) donations were retrieved, and donor demographic and donation characteristics were analyzed.
  
  
  RESULTS
  From 1993 to 1998, paid and nonpaid blood donations coexisted in Shenzhen. From the year 1999, all WB for clinical use came from VNRBDs. From 1999 to 2012, the donors who chose to donate 400 mL each time and repeat and regular donors increased sharply to meet the fast growth of clinical demand. From the year 2005, the clinical demand for PLTs was entirely satisfied by nonpaid donations.
  
  
  CONCLUSIONS
  After two decades of practice, we believe that the legal regime of VNRBD is fundamental guarantee for long-term self-sufficiency and security in the blood supply. In addition, strengthening the publicity to improve the public's awareness and improving donation services and measures to recruit more nonpaid donors and retain repeat and regular donors are very important.
authors.affiliation: Shenzhen Blood Center (SZBC), Shenzhen, Guangdong, China.
authors.forename: Bao-Cheng
authors.initials: BC
authors.lastname: Yang
authors.affiliation: Shenzhen Second People's Hospitial, Shenzhen, Guangdong, China.
authors.forename: Chao-Peng
authors.initials: CP
authors.lastname: Shao
authors.affiliation: Shenzhen Blood Center (SZBC), Shenzhen, Guangdong, China.
authors.forename: Yan-Yan
authors.initials: YY
authors.lastname: Zhang
authors.affiliation: Shenzhen Blood Center (SZBC), Shenzhen, Guangdong, China.
authors.forename: Lingkui
authors.initials: L
authors.lastname: Kong
authors.affiliation: Shenzhen Blood Center (SZBC), Shenzhen, Guangdong, China.
authors.forename: Yun-Ping
authors.initials: YP
authors.lastname: Xu
mesh_terms: D000328:Adult; D001782:Blood Donors / Q000706:statistics & numerical data*; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged