title: Mn(OAc)3-mediated phosphonation-lactonization of alkenoic acids: synthesis of phosphono-γ-butyrolactones.
abstract: A new, general method for the synthesis of phosphono-γ-butyrolactones has been achieved through Mn(OAc)3-mediated radical oxidative phosphonation and lactonization of alkenoic acids with H-phosphonates and H-phosphine oxide. Mn(OAc)3 can be readily prepared from Mn(OAc)2 in the laboratory. This transformation allows the direct formation of a P-C bond and the construction of a lactone ring in one reaction.
authors.affiliation: Department of Chemistry, College of Chemistry and Chemical Engineering, and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, Fujian 361005, China. t12g21@xmu.edu.cn.
authors.forename: Yuzhen
authors.initials: Y
authors.lastname: Gao
authors.forename: Xueqin
authors.initials: X
authors.lastname: Li
authors.forename: Jian
authors.initials: J
authors.lastname: Xu
authors.forename: Yile
authors.initials: Y
authors.lastname: Wu
authors.forename: Weizhu
authors.initials: W
authors.lastname: Chen
authors.forename: Guo
authors.initials: G
authors.lastname: Tang
authors.forename: Yufen
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D015107:4-Butyrolactone / Q000138:chemical synthesis* / Q000737:chemistry; D000085:Acetates / Q000737:chemistry*; D007783:Lactones / Q000737:chemistry; D008345:Manganese / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010746:Phosphonoacetic Acid / Q000737:chemistry*
chemical_list: D000085:Acetates; D007783:Lactones; D009942:Organometallic Compounds; C521134:manganese(III) acetate dihydrate; D008345:Manganese; D010746:Phosphonoacetic Acid; D015107:4-Butyrolactone