title: Effect of whole-body exposure to the 848.5 MHz code division multiple access (CDMA) electromagnetic field on adult neurogenesis in the young, healthy rat brain.
abstract: BACKGROUND
  Whether exposure to the 848.5 MHz code division multiple access (CDMA) signal affects adult neurogenesis is unclear.
  
  
  METHODS
  An animal experiment was performed with a reverberation chamber designed as a whole-body CDMA exposure system. Male Sprague-Dawley rats were assigned to three groups (n = 6 per group): Cage-control, sham-exposed, and CDMA-exposed groups. Rats in the CDMA-exposed group were exposed to the CDMA signal at a 2 W/kg whole-body specific absorption rate (SAR) for 1 or 8 h daily, 5 days per week, for 2 weeks. Rats received a single intraperitoneal injection of Bromodeoxyuridine (BrdU) to label proliferative cells daily for the last five consecutive days of CDMA signal exposure. An unbiased stereological method was used to estimate the number of BrdU(+) cells in the subventricular zone (SVZ) and dentate gyrus (DG).
  
  
  RESULTS
  We found no significant changes in the number of BrdU(+) cells in the SVZ or DG in the CDMA-exposed rats, compared with rats in the cage-control and sham-exposed groups (p > 0.05).
  
  
  CONCLUSIONS
  Our results suggest that exposure to the CDMA signal does not affect neurogenesis in the adult rat brain, at least under our experimental conditions.
authors.affiliation: Department of Neurosurgery, Ajou University School of Medicine , Suwon , South Korea.
authors.forename: Hye Sun
authors.initials: HS
authors.lastname: Kim
authors.forename: Yeon Ju
authors.initials: YJ
authors.lastname: Kim
authors.forename: Yu Hee
authors.initials: YH
authors.lastname: Lee
authors.forename: Yun-Sil
authors.initials: YS
authors.lastname: Lee
authors.forename: Hyung Do
authors.initials: HD
authors.lastname: Choi
authors.forename: Jeong-Ki
authors.initials: JK
authors.lastname: Pack
authors.forename: Nam
authors.initials: N
authors.lastname: Kim
authors.forename: Young Hwan
authors.initials: YH
authors.lastname: Ahn
mesh_terms: D000818:Animals; D049109:Cell Proliferation / Q000528:radiation effects; D018891:Dentate Gyrus / Q000528:radiation effects; D004574:Electromagnetic Fields; D008297:Male; D055495:Neurogenesis / Q000528:radiation effects*; D051381:Rats; D017207:Rats, Sprague-Dawley
keywords: Radio waves; bromodeoxyuridine (BrdU); cell proliferation; dentate gyrus; neurogenesis; rats; subventricular zone