title: Spiroguanidine rhodamines as fluorogenic probes for lysophosphatidic acid.
abstract: Direct determination of total lysophosphatidic acid (LPA) was accomplished using newly developed spiroguanidines derived from rhodamine B as universal fluorogenic probes. Optimum conditions for the quantitative analysis of total LPA were investigated. The linear range for the determination of total LPA is up to 5 μM with a limit of detection of 0.512 μM.
authors.affiliation: Department of Chemistry, Portland State University, Portland, OR 97201, USA. strongin@pdx.edu.
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.forename: Martha
authors.initials: M
authors.lastname: Sibrian-Vazquez
authors.forename: Jorge O
authors.initials: JO
authors.lastname: Escobedo
authors.forename: Jialu
authors.initials: J
authors.lastname: Wang
authors.forename: Richard G
authors.initials: RG
authors.lastname: Moore
authors.forename: Robert M
authors.initials: RM
authors.lastname: Strongin
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry*; D006146:Guanidines / Q000737:chemistry*; D008246:Lysophospholipids / Q000737:chemistry*; D015394:Molecular Structure; D012235:Rhodamines / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D006146:Guanidines; D008246:Lysophospholipids; D012235:Rhodamines; C029773:rhodamine B; C032881:lysophosphatidic acid