title: Mutual action of anticancer and antiparasitic drugs: are there any shared targets?
abstract: Parasites and cancers have some common features. It has been shown that some parasites interfere with tumor growth. In addition, they both have common antigens such as the Tn antigen. A communal action of anticancer and antiparasitic drugs has been reported. This shared action may be related to common targets for these drugs in cancers and parasites. In this paper, mutual action of anticancer and antiparasitic drugs, with the aim of discussing shared targets of these drugs, has been reviewed.
authors.affiliation: Department of Parasitology & Mycology, Faculty of Medicine, Isfahan University of Medical sciences, Isfahan, Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Dorosti
authors.forename: Morteza
authors.initials: M
authors.lastname: Yousefi
authors.forename: Seyedeh Maryam
authors.initials: SM
authors.lastname: Sharafi
authors.forename: Hossein Yousofi
authors.initials: HY
authors.lastname: Darani
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D000977:Antiparasitic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D058990:Molecular Targeted Therapy; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D000977:Antiparasitic Agents
keywords: cancer; drug; parasite