title: [Atypical risk factors of atherosclerosis in patients with hypothyroidism].
abstract: The non-traditional risk factors for atherosclerotic lesions of the cardiovascular system (C-reactive protein, uric acid, fibrinogen, homocysteine) in blood plasma of patients with manifestative hypothyroidism at the age of 23 to 73 years were assessed in the study. An increase in the average values of C-reactive protein was revealed in patients with hypothyroidism without arterial hypertension (AH), as well as under its presence, and increased BMI. Uric acid level also was increased with the combination of hypothyroidism and hypertension. Average level of fibrinogen was within the values of the control group and increased only in 23.4% of patients with hypothyroidism. Homocysteine content was elevated in 32% of patients and was not associated with the presence of AH. Increased levels of these markers of cardiovascular lesions risk coincided with the increased diameter of the common carotid artery.
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Mykhaĭlenko
mesh_terms: D000328:Adult; D000368:Aged; D050197:Atherosclerosis / Q000097:blood* / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D015415:Biomarkers / Q000097:blood; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000378:metabolism; D002339:Carotid Arteries / Q000473:pathology; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006710:Homocysteine / Q000097:blood; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D007037:Hypothyroidism / Q000097:blood* / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014527:Uric Acid / Q000097:blood
chemical_list: D015415:Biomarkers; D006710:Homocysteine; D014527:Uric Acid; D005340:Fibrinogen; D002097:C-Reactive Protein