title: Making metabolism accessible and meaningful: is the definition of a central metabolic dogma within reach?
abstract: Intermediary metabolism, a dominant research area before the emergence of molecular biology, is attracting renewed interest for fundamental and applied reasons as documented here. Nonetheless, the field may appear to be a thicket precluding entry to all but the most determined. Here we present a metabolic overview that makes this important and fascinating area accessible to a broad range of the molecular biological and biotechnological communities that are being attracted to biological problems crying out for metabolic solutions. This is accomplished by identifying seven key concepts, a so-called metabolic central dogma, that provide a core understanding analogous to the "Central Dogma of Molecular Biology" which focused upon maintenance and flow of genetic information.
authors.affiliation: Red Jay Consulting LLC, 20 Ringfield Road, Chadds Ford, PA, 19317, USA, jhuba73@gmail.com.
authors.forename: Robert A
authors.initials: RA
authors.lastname: LaRossa
mesh_terms: D000383:Agriculture / Q000379:methods*; D000818:Animals; D001709:Biotechnology / Q000379:methods*; D006801:Humans; D008659:Metabolic Diseases; D053858:Metabolic Networks and Pathways; D055442:Metabolome