title: [Prevalence and clinical characteristics of wheezing in children in the first year of life, living in Cuiabá, Mato Grosso, Brazil].
abstract: OBJECTIVE
  To evaluate the prevalence and the clinical characteristics of wheezing in 12-15 months old infants in the city of Cuiabá, Mato Grosso State, Midwest Brazil.
  
  
  METHODS
  Parents and/or guardians of infants were interviewed and completed a written standardized questionnaire of the "Estudio Internacional de Sibilancia en Lactantes" (EISL) - phase 3 at primary health care clinics at the same day of children vaccination or at home, from August 2009 to November 2010.
  
  
  RESULTS
  1,060 parents and/or guardians completed the questionnaire, and 514 (48.5%) infants were male. Among the studied infants, 294 (27.7%) had at least one episode of wheezing during the first year of life, beginning at 5.8±3.0 months of age, with a predominance of male patients. The prevalence of occasional wheezing (<3 episodes of wheezing) was 15.0% and recurrent wheezing (≥ 3 episodes) was 12.7%. Among the infants with recurrent wheezing, the use of inhaled β2-agonist, oral corticosteroid, leukotriene receptor antagonist, as well as night symptoms, respiratory distress and hospitalization due to severe episodes were significantly more frequent. Physician-diagnosed asthma was observed in 28 (9.5%) of the wheezing infants. Among the wheezing infants, 80 (27.7%) were diagnosed with pneumonia, of whom 33 (11.2%) required hospitalization, neverthless no differences between occasional and recurrent wheezing infants were found.
  
  
  CONCLUSIONS
  The prevalence of recurrent wheezing and physician-diagnosed asthma in infants were lower compared with those found in other Brazilian studies Recurrent wheezing had early onset and high morbity.
authors.affiliation: Universidade Federal de Mato Grosso (UFMT), Cuiabá, MT, Brasil. Electronic address: lslm44@gmail.com.
authors.forename: Lillian Sanchez Lacerda
authors.initials: LS
authors.lastname: Moraes
authors.affiliation: Universidade Federal de Mato Grosso (UFMT), Cuiabá, MT, Brasil.
authors.forename: Olga Akiko
authors.initials: OA
authors.lastname: Takano
authors.affiliation: Universidade de Santiago, Santiago, Chile.
authors.forename: Javier
authors.initials: J
authors.lastname: Mallol
authors.affiliation: Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brasil.
authors.forename: Dirceu
authors.initials: D
authors.lastname: Solé
mesh_terms: D001249:Asthma / Q000453:epidemiology*; D001938:Brazil; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D015995:Prevalence; D012135:Respiratory Sounds
keywords: Asma; Asthma; Infant; Lactente; Prevalence; Prevalência; Respiratory sounds; Sons respiratórios