title: Convexity meningioma associated with depression: a case report.
abstract: BACKGROUND
  Meningiomas are slow growing, extra-axial lesions, and can be neurologically silent for a long time and present only with depression.
  
  
  METHODS
  A 65-year-old woman developed major depression and was treated with antidepressants for two years. Depression failed to respond to drug treatment and there was no improvement. Two months before admission to hospital, due to the onset of epilepsy attack the patient underwent rein- vestigation, and a large temporal convexity meningioma, which corresponded in position to the original electroencephalography focus, was diagnosed using the computer topography of the brain. The patient underwent osteoplastic craniotomy, and a left fronto-temporal convexity meningioma of 5 cm in diameter was completely removed with its attachment to the dura. Histological examination confirmed a fibroblastic meningioma.
  
  
  CONCLUSIONS
  Total resection of convexity meningioma and decompression of the brain tissue in the region of limbic pathways that are involved, may contribute to a complete remission of depression symptoms. This case also illustrates the need for a prompt neuroimaging of the brain when patients present any atypical psychiatric symptoms, with late onset (> 50 years old) of the first depressive episode or fast changes of the mental state.
authors.forename: Nenad
authors.initials: N
authors.lastname: Zivković
authors.forename: Marko
authors.initials: M
authors.lastname: Marković
authors.forename: Milan
authors.initials: M
authors.lastname: Spaić
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology; D003399:Craniotomy; D003863:Depression; D003865:Major Depressive Disorder / Q000209:etiology*; D004388:Dura Mater / Q000473:pathology; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000150:complications* / Q000523:psychology; D008579:Meningioma / Q000150:complications* / Q000523:psychology; D019651:Plastic Surgery Procedures