title: [An analysis on Pf60.1 gene polymorphism of Plasmodium falciparum from imported cases].
abstract: One hundred and one imported falciparum malaria cases in Wuhan City were confirmed by microscopy and Nest-PCR, and the blood samples were collected. The Pf60.1 gene was amplified by PCR. Among 101 blood samples, three Pf60.1 fragments [313 bp (56.5%, 52/92), 340 bp (37.0%, 34/92), 313 bp+340 bp (6.5%, 6/92)] were amplified from 92 samples. Among 83 blood samples from patients returning from Africa, 313 bp fragment were found in 46 samples (55.4%, 46/83), 340 bp fragment were found in 31 samples (37.1%, 31/83), and 7.2% (6/83) was mixed-fragment (313 bp+340 bp). Among 9 samples from southeast Asia, 6 samples were with 313 bp fragment and 3 samples with 340 bp fragment. The results indicated that the most common genotype was 313 bp-genotype, and there would be polyclonal P. falciparum infections.
authors.forename: Kai
authors.initials: K
authors.lastname: Wu
authors.forename: Shui-mao
authors.initials: SM
authors.lastname: Zhou
authors.forename: Yan
authors.initials: Y
authors.lastname: Yang
authors.forename: Chong-xin
authors.initials: CX
authors.lastname: Wang
authors.forename: Ming-xing
authors.initials: MX
authors.lastname: Xu
mesh_terms: D006801:Humans; D016778:Malaria, Falciparum / Q000469:parasitology*; D008853:Microscopy; D010963:Plasmodium falciparum / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D015800:Protozoan Proteins / Q000235:genetics*
chemical_list: D015800:Protozoan Proteins