title: Protracted febrile myalgia syndrome in a Japanese patient with fasciitis detected on MRI.
abstract: Protracted febrile myalgia syndrome (PFMS) is a rare manifestation of familial Mediterranean fever characterized by prolonged severe myalgia. We herein describe a case of PFMS with fasciitis on magnetic resonance imaging. The response to corticosteroid therapy was prompt, as is typical for PFMS. An MEFV gene analysis revealed the patient to be homozygous for E148Q and compound heterozygous for P369S-R408Q. This is the first case report of a Japanese patient with PFMS. MRI findings may help to diagnose such cases.
authors.affiliation: Department of Rheumatology, Japan Community Health Care Organization (JCHO), Isahaya General Hospital, Japan.
authors.forename: Keita
authors.initials: K
authors.lastname: Fujikawa
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Migita
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Tsukada
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kawakami
authors.forename: Katsumi
authors.initials: K
authors.lastname: Eguchi
mesh_terms: D010505:Familial Mediterranean Fever / Q000150:complications* / Q000175:diagnosis* / Q000235:genetics; D005208:Fasciitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007564:Japan; D008297:Male; D063806:Myalgia / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D011239:Prednisolone / Q000627:therapeutic use; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone