title: Assessment of the relationship between lipid parameters and obesity indices in non-diabetic obese patients: a preliminary report.
abstract: BACKGROUND
  The aim of this cross-sectional study was to examine the relationship between obesity and lipid markers.
  
  
  METHODS
  We divided 66 non-diabetic adult obese patients (mean age: 55.8±11.6 years) into 3 groups according to body mass index (BMI). All patients were measured for waist circumference (WC), hip circumference (HC), body mass index (BMI), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), body adiposity index (BAI), and visceral adiposity index (VAI). Serum levels of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG) were determined, and lipid indices TC/HDL, LDL/HDL, and TG/HDL were also estimated.
  
  
  RESULTS
  TC and LDL-C in Group III were lower than in Group I (5.0±1.0 vs. 6.0±1.0 mmol/L, and 2.9±0.9 vs. 3.8±1.2 mmol/L; p<0.05 for both). Negative correlations were found between: BMI and TC, LDL, and HDL (r=-0.291; r=-0.310, r=-0.240, respectively); and WC, WHR, VAI, and HDL (r=-0.371, r=-0.296, r=-0.376, respectively). Positive correlations were found between WC, WHR, and TG/HDL (r=0.279, r=0.244, respectively) and between VAI and: TC (r=0.327), TG (r=0.885), TC/HDL (r=0.618), LDL/HDL (r=0.480), and TG/HDL (r=0.927).
  
  
  CONCLUSIONS
  Obesity is associated with lipid disturbances, especially with HDL-C reduction, in obese non-diabetic patients. VAI is strongly related to lipid profile and thus may be the most valuable obesity index in obese patients with dyslipidemias.
authors.affiliation: Department of Nephrology, Hypertension and Family Medicine, Medical University of Łódź, Łódź, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Stępień
authors.affiliation: Department of Nephrology, Hypertension and Family Medicine, Medical University of Łódź, Łódź, Poland.
authors.forename: Mariusz
authors.initials: M
authors.lastname: Stępień
authors.affiliation: Department of Laboratory Diagnostics and Clinical Biochemistry, Medical University of Łódź, Łódź, Poland.
authors.forename: Rafał N
authors.initials: RN
authors.lastname: Wlazeł
authors.affiliation: Department of Laboratory Diagnostics and Clinical Biochemistry, Medical University of Łódź, Łódź, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Paradowski
authors.affiliation: Department of Hypertension, Medical University of Łódź, Łódź, Poland.
authors.forename: Maciej
authors.initials: M
authors.lastname: Banach
authors.affiliation: Department of Nephrology, Hypertension and Family Medicine, Medical University of Łódź, Łódź, Poland.
authors.forename: Jacek
authors.initials: J
authors.lastname: Rysz
mesh_terms: D003920:Diabetes Mellitus / Q000097:blood*; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood*
chemical_list: D008055:Lipids