title: Building through breaking: the development of cancer neochromosomes.
abstract: In this issue of Cancer Cell, Garsed and colleagues combine chromosome flow sorting and deep sequencing to characterize the structure of oncogene-containing neochromosomes in liposarcoma and provide evidence that they are generated by a combination of multiple dynamic and destructive processes.
authors.affiliation: Genetics Branch, Center for Cancer Research, National Cancer Institute, 37 Convent Drive, Bethesda, MD 20892, USA.
authors.forename: Joshua J
authors.initials: JJ
authors.lastname: Waterfall
authors.affiliation: Genetics Branch, Center for Cancer Research, National Cancer Institute, 37 Convent Drive, Bethesda, MD 20892, USA. Electronic address: pmeltzer@mail.nih.gov.
authors.forename: Paul S
authors.initials: PS
authors.lastname: Meltzer
mesh_terms: D002877:Chromosomes, Human / Q000235:genetics*; D005260:Female; D006801:Humans; D008080:Liposarcoma / Q000235:genetics*; D012186:Retroperitoneal Neoplasms / Q000235:genetics*