title: Efficacy of veno-venous extracorporeal membrane oxygenation in severe acute respiratory failure.
abstract: OBJECTIVE
  The objective of this study was to evaluate our institutional experience with veno-venous (VV) extracorporeal membrane oxygenation (ECMO) in patients with severe acute respiratory failure (ARF).
  
  
  METHODS
  From January 2007 to August 2013, 31 patients with severe ARF that was due to various causes and refractory to mechanical ventilation with conventional therapy were supported with VV ECMO. A partial pressure of arterial oxygen (PaO₂)/inspired fraction of oxygen (FiO₂) <100 mm Hg at an FiO₂ of 1.0 or a pH <7.25 due to CO₂ retention were set as criteria for VV ECMO.
  
  
  RESULTS
  Overall, 68% of patients survived among those who had received VV ECMO with a mean PaO₂/FiO₂ of 56.8 mm Hg. Furthermore, in trauma patients, early use of ECMO had the best outcome with a 94% survival rate.
  
  
  CONCLUSIONS
  VV ECMO is an excellent, life-saving treatment option in patients suffering from acute and life-threatening respiratory failure due to various causes, especially trauma, and early use of VV ECMO therapy improved outcomes in these patients.
authors.affiliation: Department of Anesthesiology, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Jae Jun
authors.initials: JJ
authors.lastname: Lee
authors.affiliation: Department of Anesthesiology, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Sung Mi
authors.initials: SM
authors.lastname: Hwang
authors.affiliation: Department of Anesthesiology, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Jae Houn
authors.initials: JH
authors.lastname: Ko
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, School of Medicine, Hallym University, Chuncheon, Korea. cskhs99@hallym.or.kr.
authors.forename: Hyoung Soo
authors.initials: HS
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Department of Internal Medicine, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Kyung Soon
authors.initials: KS
authors.lastname: Hong
authors.affiliation: Division of Cardiology, Department of Internal Medicine, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Hyun Hee
authors.initials: HH
authors.lastname: Choi
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Myung Goo
authors.initials: MG
authors.lastname: Lee
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Chang Youl
authors.initials: CY
authors.lastname: Lee
authors.affiliation: Department of Urology, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Won Ki
authors.initials: WK
authors.lastname: Lee
authors.affiliation: Department of Emergency Medicine, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Eun Jin
authors.initials: EJ
authors.lastname: Soun
authors.affiliation: Department of Emergency Medicine, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Tae Hun
authors.initials: TH
authors.lastname: Lee
authors.affiliation: Department of Emergency Medicine, School of Medicine, Hallym University, Chuncheon, Korea.
authors.forename: Jeong Yeol
authors.initials: JY
authors.lastname: Seo
mesh_terms: D000208:Acute Disease; D000328:Adult; D002423:Cause of Death; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012131:Respiratory Insufficiency / Q000150:complications / Q000628:therapy*; D016019:Survival Analysis; D016896:Treatment Outcome
keywords: Acute respiratory failure; extracorporeal membrane oxygenation; mechanical ventilation; survival rate