title: Successful Thrombolysis despite Having an Incidental Unruptured Cerebral Aneurysm.
abstract: Purpose. To report a case of successful thrombolysis performed in a patient with an incidental unruptured intracranial aneurysm and review the literature. Case Report. Patient admitted for ischemic stroke due to left posterior cerebral artery occlusion, with an incidental right middle cerebral artery aneurysm, who underwent treatment with tissue plasminogen activator (rtPA) resulting in clinical improvement without complications. Conclusion. The presence of unruptured intracranial aneurysms is considered as a contraindication to thrombolysis, due to a potentially higher hemorrhagic risk of aneurysm rupture. Patients, otherwise, eligible for thrombolysis are usually excluded from receiving this emergent treatment, despite its potential benefits. A reevaluation of the strict exclusion criteria for thrombolysis in acute stroke patients should be considered.
authors.affiliation: Internal Medicine Department, Centro Hospitalar Leiria-Pombal, EPE, Hospital de Santo André, 2410-197 Leiria, Portugal.
authors.forename: Diana
authors.initials: D
authors.lastname: Briosa E Gala
authors.affiliation: Internal Medicine Department, Centro Hospitalar de Lisboa Central, EPE, Hospital de Santa Marta, 1169-024 Lisboa, Portugal.
authors.forename: André
authors.initials: A
authors.lastname: Almeida
authors.affiliation: Internal Medicine Department, Centro Hospitalar de Lisboa Ocidental, EPE, Hospital Egas Moniz, 1349-019 Lisboa, Portugal.
authors.forename: Nadine
authors.identifier: 0000-0003-3079-7789
authors.initials: N
authors.lastname: Monteiro
authors.affiliation: Cerebrovascular Unit, Centro Hospitalar de Lisboa Central, EPE, Hospital de São José, 1150-199 Lisboa, Portugal.
authors.forename: Ana
authors.initials: A
authors.lastname: Paiva Nunes
authors.affiliation: Cerebrovascular Unit, Centro Hospitalar de Lisboa Central, EPE, Hospital de São José, 1150-199 Lisboa, Portugal.
authors.forename: Patrícia
authors.initials: P
authors.lastname: Ferreira
authors.affiliation: Cerebrovascular Unit, Centro Hospitalar de Lisboa Central, EPE, Hospital de São José, 1150-199 Lisboa, Portugal.
authors.forename: Nuno
authors.initials: N
authors.lastname: Mendonça
authors.affiliation: Cerebrovascular Unit, Centro Hospitalar de Lisboa Central, EPE, Hospital de São José, 1150-199 Lisboa, Portugal.
authors.forename: Alexandre
authors.identifier: 0000-0002-7899-3634
authors.initials: A
authors.lastname: Amaral-Silva
authors.affiliation: Cerebrovascular Unit, Centro Hospitalar de Lisboa Central, EPE, Hospital de São José, 1150-199 Lisboa, Portugal.
authors.forename: João
authors.initials: J
authors.lastname: Alcântara