title: Synthesis and stability of boratriazaroles.
abstract: We describe the synthesis and stability analysis of novel boratriazaroles that can be viewed as bioisosteres of imidazoles or pyrazoles. These heterocycles could conveniently be obtained by condensing a boronic acid and amidrazone 1 in various solvents. A detailed stability analysis of selected compounds at different pH values as a function of time led to the identification of steric hindrance around the boron atom as a key element for stabilization.
authors.affiliation: Syngenta Crop Protection Münchwilen AG , WST-820.2.14, Schaffhauserstrasse, CH-4332 Stein, AG, Switzerland.
authors.forename: Didier
authors.initials: D
authors.lastname: Zurwerra
authors.forename: Vincent
authors.initials: V
authors.lastname: Quetglas
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Kloer
authors.forename: Peter
authors.initials: P
authors.lastname: Renold
authors.forename: Thomas
authors.initials: T
authors.lastname: Pitterna