title: Epidemiological characterization and risk factors of allergic rhinitis in the general population in Guangzhou City in china.
abstract: The prevalence of allergic rhinitis (AR) in China has increased with an apparent geographic variation. The current study aims to investigate the AR prevalence/classification, diagnosis/treatment conditions, trigger factors, and risk factors in the general population of Guangzhou, the third biggest city in China. A cross-sectional survey was performed in the citizens in Guangzhou from December 2009 to March 2010 by using a stratified multistage cluster sampling method. All subjects were asked to complete a comprehensive questionnaire via a face to face interview. A total of 9,899 questionnaires were valid. The prevalence rate of AR in the general population of Guangzhou was 6.24%, with a significant higher prevalence in urban area (8.32%) versus rural area (3.43%). Among the AR subjects, most (87%) were diagnosed with intermittent AR and 87% suffered from moderate-severe symptoms. High percentages of the AR patients did not have previously physician-based diagnosis (34%) or specific medical treatment (55%). Morning time, winter season, and cold air were the most common trigger factors of AR. Family history of AR, current living place, living place during babyhood, smoking, home renovation, and pet ownership were the significant risk factors associated with AR prevalence in the population. The study demonstrated comprehensive epidemiological and clinical information about the AR in Guangzhou population. Change of living environment and lifestyles had strong impacts on the prevalence of AR. Public health policies should help the patients benefit from a proper diagnosis/treatment and specifically target the local risk factors, in order to control the AR incidence.
authors.affiliation: Department of Otolaryngology, National University of Singapore, National University Health System, Singapore.
authors.forename: Chun Wei
authors.initials: CW
authors.lastname: Li
authors.affiliation: Department of Allergy, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
authors.forename: De Hua
authors.initials: DH
authors.lastname: Chen
authors.affiliation: Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
authors.forename: Jia Tao
authors.initials: JT
authors.lastname: Zhong
authors.affiliation: Department of Allergy, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
authors.forename: Zhi Bin
authors.initials: ZB
authors.lastname: Lin
authors.affiliation: Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Peng
authors.affiliation: Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
authors.forename: Han Gui
authors.initials: HG
authors.lastname: Lu
authors.affiliation: Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Yin
authors.affiliation: Department of Allergy, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China; Department of Otorhinolaryngology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
authors.forename: Tian Ying
authors.initials: TY
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D005843:Geography; D006801:Humans; D008297:Male; D008875:Middle Aged; D012221:Rhinitis, Allergic, Perennial / Q000453:epidemiology*; D006255:Rhinitis, Allergic, Seasonal / Q000453:epidemiology*; D012307:Risk Factors; D012621:Seasons; D012907:Smoking / Q000009:adverse effects; D011795:Surveys and Questionnaires; D055815:Young Adult