title: Impact of hemostasis methods, electrocoagulation versus suture, in laparoscopic endometriotic cystectomy on the ovarian reserve: a randomized controlled trial.
abstract: OBJECTIVE
  To evaluate the impact on ovarian reserve between two different methods ofhemostasis after laparoscopic ovarian endometrioma excision.
  
  
  METHODS
  A randomized controlled study was conducted from January to December 2013 in Thammasat University Hospital, Thailand. Reproductive women, age 18-45years who underwent laparoscopic ovarian cystectomy were randomized in electrocoagulation and suture groups. Clinical baseline data and ovarian reserve outcome (anti-Mullerian hormone (AMH)) were evaluated.
  
  
  RESULTS
  Fifty participants were recruited and randomized in two groups. Electrocoagulation and suture groups consisted of 25 participants. Baseline characteristics between 2 groups (age, weight, BMI, height, cyst diameter, duration and estimated blood loss) were not statistically different. There were no significant difference of AMIH between electrocoagulation and suture group atpre-operative (2.90±2.26 vs. 2.52±2.37 ng/ml), 1 week (1.78±1.51 vs. 1.99±1.71 ng/ml), 1 month (1.76±1.50 vs. 2.09±1.62 ng/ml), 3 months (2.09±1.66 vs. 1.96±1.68 ng/ml) and 6 months (2.11±1.84 vs 1.72±1.68 ng/ml), respectively. However mean AMH ofboth groups significantly decreased since the first week of operation. Effect oflaparoscopic ovarian surgery had significantly declined and sustained AMH level until 6 months.
  
  
  CONCLUSIONS
  Laparoscopic cystectomy of ovarian endometrioma has negative impact to ovarian reserve. Either electroco- agulation or suture method had no different effects.
authors.forename: Chamnan
authors.initials: C
authors.lastname: Tanprasertkul
authors.forename: Sophapun
authors.initials: S
authors.lastname: Ekarattanawong
authors.forename: Opas
authors.initials: O
authors.lastname: Sreshthaputra
authors.forename: Teraporn
authors.initials: T
authors.lastname: Vutyavanich
mesh_terms: D000293:Adolescent; D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood; D003560:Cysts / Q000601:surgery*; D004564:Electrocoagulation; D004715:Endometriosis / Q000601:surgery*; D005260:Female; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D010049:Ovarian Diseases / Q000601:surgery*; D065851:Ovarian Reserve; D013536:Suture Techniques; D013785:Thailand; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D054304:Anti-Mullerian Hormone