title: [Mindfulness, depression, quality of life, and cancer: The nonlinear, indirect effect of mindfulness on the quality of life of cancer patients].
abstract: OBJECTIVE
  This study investigates the relationships between mindfulness, depression, and quality of life (QoL) in cancer patients.
  
  
  METHODS
  A total of 51 cancer patients were assessed with the FreiburgMindfulness Inventory (FFA;Walach et al. 2004), the Hospital Anxiety and Depression Scale (HADS-D; Herrmann et al. 1994), and the Schedule for the Evaluation of Individual Quality of Life -DW (SEI QoLDW; Browne et al. 1997). The nonlinear relationships were analyzed using the instantaneous indirect effect procedure by Hayes and Preacher (2010).
  
  
  RESULTS
  The relationship between mindfulness and QoL is mediated by depression. Because the relationship between mindfulness and depression is squared, the total effect of mindfulness on QoL is not constant. Increasing the level of mindfulness results in a decrease in its effect on the QoL of cancer patients.
  
  
  CONCLUSIONS
  Cancer patients benefit from mindfulness up to a medium level through a decrease in depression, resulting in higher QoL. Patients with very higher mindfulness show more depressive symptoms, which leads to a neutralization of the effect of mindfulness on QoL.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Blawath
authors.forename: Ruth
authors.initials: R
authors.lastname: Metten
authors.forename: Volker
authors.initials: V
authors.lastname: Tschuschke
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D003863:Depression / Q000175:diagnosis / Q000523:psychology* / Q000628:therapy*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D064866:Mindfulness; D009369:Neoplasms / Q000523:psychology*; D017711:Nonlinear Dynamics; D010166:Palliative Care / Q000523:psychology; D011594:Psychometrics / Q000706:statistics & numerical data; D011788:Quality of Life / Q000523:psychology*; D011795:Surveys and Questionnaires
keywords: Cancer Patients; Depression; Mindfulness; Nonlinear Mediation; Quality of Life