title: [T-lymphocyte-helper type 17 mediated regulation of antibacterial (antituberculosis) immunity].
abstract: The analysis of current views on functional and immunoregulatory role of T-lymphocytes-helpers of type 17 (Th17) in anti-infectious immune response is presented, in particular, in the development of protective immune reactions to intracellular pathogens. Particular attention is paid to participation of these lymphocytes and cytokines produced by them in immune response to Mycobacterium tuberculosis invasion. The molecular mechanisms, underlying the predominant development of Th17-lymphocytes and/or regulatory T-cells (Treg), are studied, with evaluation of interconnection of these cell subpopulations in formation of immune imbalance in infectious pathology.
authors.forename: T E
authors.initials: TE
authors.lastname: Kononova
authors.forename: O I
authors.initials: OI
authors.lastname: Urazova
authors.forename: V V
authors.initials: VV
authors.lastname: Novitskiĭ
authors.forename: E G
authors.initials: EG
authors.lastname: Churina
mesh_terms: D016207:Cytokines / Q000096:biosynthesis / Q000276:immunology*; D006801:Humans; D007113:Immunity, Innate; D009169:Mycobacterium tuberculosis / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology; D058504:Th17 Cells / Q000276:immunology*; D014376:Tuberculosis / Q000276:immunology* / Q000382:microbiology / Q000628:therapy
chemical_list: D016207:Cytokines