title: Transmission-Blocking Vaccines: Focus on Anti-Vector Vaccines against Tick-Borne Diseases.
abstract: Tick-borne diseases are a potential threat that account for significant morbidity and mortality in human population worldwide. Vaccines are not available to treat several of the tick-borne diseases. With the emergence and resurgence of several tick-borne diseases, emphasis on the development of transmission-blocking vaccines remains increasing. In this review, we provide a snap shot on some of the potential candidates for the development of anti-vector vaccines (a form of transmission-blocking vaccines) against wide range of hard and soft ticks that include Ixodes, Haemaphysalis, Dermacentor, Amblyomma, Rhipicephalus and Ornithodoros species.
authors.affiliation: Center for Molecular Medicine, Department of Biological Sciences, Old Dominion University, Norfolk, VA, 23529, USA, gneelaka@odu.edu.
authors.forename: Girish
authors.initials: G
authors.lastname: Neelakanta
authors.forename: Hameeda
authors.initials: H
authors.lastname: Sultana
mesh_terms: D000818:Animals; D005822:Genetic Vectors; D006801:Humans; D017282:Tick-Borne Diseases / Q000628:therapy* / Q000635:transmission; D013987:Ticks; D014612:Vaccines
chemical_list: D014612:Vaccines