title: Exploring associations between anthropometric indices and graft function in patients receiving renal transplant.
abstract: BACKGROUND
  The aim of the present study was to identify indicators of malnutrition, as obtained by anthropometric measurements, that might be potential predictors of transplant outcomes.
  
  
  METHODS
  One hundred and three patients receiving a graft from a living or a deceased donor were included in this prospective study. Body mass index (BMI) based on pretransplant dry body weight, triceps skinfold, mid-arm muscle circumference and corrected mid-arm muscle area were measured. Post-transplant data on delayed graft function (DGF) and glomerular filtration rate (GFR) at discharge were collected until patient discharge.
  
  
  RESULTS
  Delayed graft function developed in 36.9% of the patients. BMI was the only anthropometric variable associated with a higher likelihood of DGF (odds ratio = 1.25, 95% confidence interval = 1.07-1.47) after adjusting for age, gender, donor group, donor age and years of dialysis before transplantation. Obesity was associated with a higher frequency of DGF (83.3% versus 31.1%, P = 0.001) compared to normal weight. GFR at discharge was negatively associated with BMI [β = -0.014 (0.005), P = 0.004], being overweight [β = -0.151 (0.041), P < 0.001] and obesity [β = -0.188 (0.053), P = 0.001], after adjusting for age, gender, donor group, donor age and years of dialysis, but was not associated with indices of muscle reserves.
  
  
  CONCLUSIONS
  The likelihood of DGF was higher among obese patients, whereas GFR at discharge was negatively associated with being overweight and obesity.
authors.affiliation: Department of Nutrition & Dietetics, Harokopio University, Athens, Greece.
authors.forename: L
authors.initials: L
authors.lastname: Tsirigoti
authors.affiliation: Department of Nutrition & Dietetics, Harokopio University, Athens, Greece.
authors.forename: M D
authors.initials: MD
authors.lastname: Kontogianni
authors.affiliation: Department of Nephrology & Transplantation Unit, Laiko Hospital, Athens, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Darema
authors.affiliation: Department of Nutrition & Dietetics, Harokopio University, Athens, Greece.
authors.forename: V
authors.initials: V
authors.lastname: Iatridi
authors.affiliation: Department of Nephrology & Transplantation Unit, Laiko Hospital, Athens, Greece.
authors.forename: N
authors.initials: N
authors.lastname: Altanis
authors.affiliation: Department of Nutrition & Dietetics, Laiko Hospital, Athens, Greece.
authors.forename: K A
authors.initials: KA
authors.lastname: Poulia
authors.affiliation: Transplantation Unit, Laiko Hospital, Athens, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Zavos
authors.affiliation: Department of Nephrology & Transplantation Unit, Laiko Hospital, Athens, Greece.
authors.forename: J
authors.initials: J
authors.lastname: Boletis
mesh_terms: D000328:Adult; D001132:Arm; D015992:Body Mass Index; D001835:Body Weight; D051799:Delayed Graft Function / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D016030:Kidney Transplantation; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000502:physiology; D009765:Obesity / Q000150:complications / Q000503:physiopathology; D050177:Overweight / Q000150:complications / Q000503:physiopathology; D011446:Prospective Studies
keywords: anthropometry; delayed graft function; nutritional assessment; obesity; renal transplantation