title: Pluripotent-stem-cell-derived epicardial cells: a step toward artificial cardiac tissue.
abstract: Epicardial cells are crucial for heart development, function, and regeneration, but methods to study them have been lacking. Using WNT and BMP signaling pathways, Witty et al. (2014) have now developed an elaborate method to generate fully functional epicardial cells from human pluripotent stem cells, allowing their in vitro investigation.
authors.affiliation: Department of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria. Electronic address: mail@med.cbrenner.net.
authors.forename: Christoph
authors.initials: C
authors.lastname: Brenner
authors.affiliation: Department of Internal Medicine III, Cardiology and Angiology, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria. Electronic address: wolfgang-michael.franz@uki.at.
authors.forename: Wolfgang-Michael
authors.initials: WM
authors.lastname: Franz
mesh_terms: D000818:Animals; D019070:Cell Lineage / Q000502:physiology*; D006801:Humans; D010496:Pericardium / Q000166:cytology*; D039904:Pluripotent Stem Cells / Q000166:cytology*