title: [The hand, foot and mouth disease. Clinical premiere in our country].
abstract: In May 1981 the hand, foot and mouth disease was diagnosed for the first time in Ramaia in a 4 year old child. The onset of the disease was characterized by moderate fever, coryza and spontaneous endobuccal pains followed at a short interval of time by the simultaneous of a papulo-vesicular eruption on hands and feet. The eruption was prevalent on the hands and feet fingers as well as on the palmar and plantar regions. Isolated aphthous lesions were seen on the vestibular mucosa. Morphologically, the intraepidermic site of the lesion with an advanced acantholytic process in the vesicular area was noticed. In the superficial and deep tissue perivascular infiltrate with mononucleares were present.
authors.forename: E
authors.initials: E
authors.lastname: Brauner
authors.forename: F
authors.initials: F
authors.lastname: Dănilă
authors.forename: A
authors.initials: A
authors.lastname: Rădulescu
authors.forename: T
authors.initials: T
authors.lastname: Turcu
authors.forename: C
authors.initials: C
authors.lastname: Vîntu
authors.forename: T
authors.initials: T
authors.lastname: Hurmuzache
authors.forename: C
authors.initials: C
authors.lastname: Vătavu
authors.forename: P
authors.initials: P
authors.lastname: Damir
authors.forename: A
authors.initials: A
authors.lastname: Colţea
authors.forename: L
authors.initials: L
authors.lastname: Bărăscu
authors.forename: L
authors.initials: L
authors.lastname: Gavriliţă
authors.forename: E
authors.initials: E
authors.lastname: Labă
authors.forename: O
authors.initials: O
authors.lastname: Zavate
authors.forename: F
authors.initials: F
authors.lastname: Cotor
authors.forename: A
authors.initials: A
authors.lastname: Ivan
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D004770:Enterovirus / Q000302:isolation & purification; D005076:Exanthema / Q000473:pathology / Q000821:virology; D005385:Fingers / Q000473:pathology / Q000821:virology; D005528:Foot / Q000473:pathology / Q000821:virology; D006225:Hand / Q000473:pathology / Q000821:virology; D006232:Hand, Foot and Mouth Disease / Q000175:diagnosis* / Q000821:virology*; D006801:Humans; D008297:Male; D009055:Mouth / Q000473:pathology; D012383:Romania; D013281:Stomatitis, Aphthous / Q000473:pathology* / Q000821:virology*