title: Nanostructured microfluidic digestion system for rapid high-performance proteolysis.
abstract: A novel microfluidic protein digestion system with a nanostructured and bioactive inner surface was constructed by an easy biomimetic self-assembly strategy for rapid and effective proteolysis in 2 minutes, which is faster than the conventional overnight digestion methods. It is expected that this work would contribute to rapid online digestion in future high-throughput proteomics.
authors.affiliation: Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802, USA. sxz10@psu.edu.
authors.forename: Gong
authors.initials: G
authors.lastname: Cheng
authors.forename: Si-Jie
authors.initials: SJ
authors.lastname: Hao
authors.forename: Xu
authors.initials: X
authors.lastname: Yu
authors.forename: Si-Yang
authors.initials: SY
authors.lastname: Zheng
mesh_terms: D056656:Lab-On-A-Chip Devices; D008958:Models, Molecular; D049329:Nanostructures / Q000737:chemistry*; D010316:Particle Size; D059748:Proteolysis; D013499:Surface Properties