title: [Morphological features of oesophagogastric junction mucosa in children with gastroesophageal reflux disease].
abstract: In present work we studied the morphological features of the esophageal mucosa in 63 children with gastroesophageal reflux disease (GERD). The biopsies were taken at level of 3 cm above a Z-line and at level of 0.5-1 cm above a Z-line. The results of our study showed that the mucosa of the esophago-gastric junction may contain areas covered with columnar epithelium of 44.4% of children in the biopsies from the level of 0.5-1.0 cm above the Z-line. Inflammatory changes in the mucosa of the esophago-gastric junction identified in 71.4% of cases. The inflammation in the majority of cases (82.1%) was observed in the presence of H. pylori infection (p < 0.001). In addition, H. pylori in our study, we noted the relationship detection carditis in overweight child. When compared with the height-weight parameters, the excess body weight was observed in 17 of 28 patients. We couldn't found increasing detection of the cardia in patients with erosive GERD compared with non-erosive variants.
authors.forename: A S
authors.initials: AS
authors.lastname: Tertychnyĭ
authors.forename: S I
authors.initials: SI
authors.lastname: Mamchenko
authors.forename: M I
authors.initials: MI
authors.lastname: Dubrovskaia
authors.forename: N R
authors.initials: NR
authors.lastname: Petrosian
authors.forename: M A
authors.initials: MA
authors.lastname: Kvirkeliia
authors.forename: P M
authors.initials: PM
authors.lastname: Tsvetkov
authors.forename: A V
authors.initials: AV
authors.lastname: Krasavin
authors.forename: N S
authors.initials: NS
authors.lastname: Marenich
mesh_terms: D000293:Adolescent; D001706:Biopsy; D002648:Child; D016145:Endoscopy, Digestive System; D004943:Esophagogastric Junction / Q000382:microbiology / Q000473:pathology*; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology*; D005764:Gastroesophageal Reflux / Q000150:complications / Q000382:microbiology / Q000473:pathology*; D016481:Helicobacter Infections / Q000150:complications / Q000382:microbiology / Q000473:pathology*; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D050177:Overweight / Q000150:complications / Q000382:microbiology / Q000473:pathology*