title: [Should pediatric parenteral nutrition be individualized?].
abstract: BACKGROUND
  Parenteral nutrition (PN) formulations are commonly individualized, since their standardization seem inadequate for the pediatric population. This study aimed to evaluate the nutritional state and the reasons for PN individualization in pediatric patients using PN hospitalized in a tertiary hospital in Campinas, São Paulo.
  
  
  METHODS
  This longitudinal study comprised patients using PN followed by up to 67 days. Nutritional status was classified according to the criteria established by the World Health Organization (WHO) (2006) and WHO (2007). The levels of the following elements on blood were analyzed: sodium, potassium, ionized calcium, chloride, magnesium, inorganic phosphorus and triglycerides (TGL). Among the criteria for individualization, were considered undeniable: significant reduction in blood levels of potassium (<3 mEq/L), sodium (<125 mEq/)L, magnesium (<1 mEq/L), phosphorus (<1.5 mEq/L), ionic calcium (<1 mmol) and chloride (<90 mEq/L) or any value above the references.
  
  
  RESULTS
  Twelve pediatric patients aged 1 month to 15 years were studied (49 individualizations). Most patients were classified as malnourished. It was observed that 74/254 (29.2%) of examinations demanded individualized PN by indubitable reasons.
  
  
  CONCLUSIONS
  The nutritional state of patients was considered critical in most cases. Thus, the individualization performed in the beginning of PN for energy protein adequacy was indispensable. In addition, the individualized PN was indispensable in at least 29.2% of PN for correction of alterations found in biochemical parameters.
authors.affiliation: Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brasil. Electronic address: renatagbonfreitas@yahoo.com.br.
authors.forename: Renata Germano Borges de Oliveira Nascimento
authors.initials: RG
authors.lastname: Freitas
authors.affiliation: Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brasil.
authors.forename: Roberto José Negrão
authors.initials: RJ
authors.lastname: Nogueira
authors.affiliation: Centro Universitário de Volta Redonda, Volta Redonda, RJ, Brasil.
authors.forename: Margareth Lopes Galvão
authors.initials: ML
authors.lastname: Saron
authors.affiliation: Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brasil.
authors.forename: Alexandre Esteves Souza
authors.initials: AE
authors.lastname: Lima
authors.affiliation: Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brasil.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Hessel
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D009752:Nutritional Status; D010288:Parenteral Nutrition; D057285:Precision Medicine
keywords: Child; Criança; Estado nutricional; Nutritional status; Nutrição parenteral; Parenteral nutrition