title: Application of the Human Intestinal Tract Chip to the non-human primate gut microbiota.
abstract: The human intestinal microbiota is responsible for various health-related functions, and its diversity can be readily mapped with the 16S ribosomal RNA targeting Human Intestinal Tract (HIT) Chip. Here we characterise distal gut samples from chimpanzees, gorillas and marmosets, and compare them with human gut samples. Our results indicated applicability of the HITChip platform can be extended to chimpanzee and gorilla faecal samples for analysis of microbiota composition and enterotypes, but not to the evolutionary more distant marmosets.
authors.affiliation: Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, the Netherlands.
authors.forename: T D J
authors.initials: TD
authors.lastname: Bello González
authors.affiliation: Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, the Netherlands National Institute for Public Health and the Environment, Postbus 1, 3720 BA Bilthoven, the Netherlands.
authors.forename: M W J
authors.initials: MW
authors.lastname: van Passel
authors.affiliation: Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, the Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Tims
authors.affiliation: Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, the Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Fuentes
authors.affiliation: Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, the Netherlands Department of Veterinary Biosciences, Helsinki University, P.O. Box 66, 00014 Helsinki, Finland Department of Bacteriology and Immunology, Helsinki University, P.O. Box 21, 00014 Helsinki, Finland.
authors.forename: W M
authors.initials: WM
authors.lastname: De Vos
authors.affiliation: Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, the Netherlands.
authors.forename: H
authors.initials: H
authors.lastname: Smidt
authors.affiliation: Laboratory of Microbiology, Wageningen University, Dreijenplein 10, 6703 HB Wageningen, the Netherlands.
authors.forename: C
authors.initials: C
authors.lastname: Belzer
mesh_terms: D000818:Animals; D001419:Bacteria / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000235:genetics; D005243:Feces / Q000382:microbiology; D000069196:Gastrointestinal Microbiome; D006071:Gorilla gorilla / Q000382:microbiology*; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D020411:Oligonucleotide Array Sequence Analysis; D002679:Pan troglodytes / Q000382:microbiology*; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics
chemical_list: D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S
keywords: enterotypes; microbiota; non-human primates; phylogenetic profile