title: [Application of the xenogenic acellular dermal matrix membrane application used in the postoperative tissue shortage repair].
abstract: OBJECTIVE
  To observe the short-term and long-term curative effect of the xenogenic acellular dermal matrix membrane (or joint muscle flap transfer) application used in the 82 cases postoperative tissue shortage repair that after the head neck carcinoma resection.
  
  
  METHODS
  To held the 82 cases head neck carcinoma postoperative mucosa shortage repaired after resection by the xenogenic acellular dermal matrix membrane (or joint muscle flap transfer), 65 cases mucosa shortage wound be directly covered by the repair membrane and the other 17 cases mucosa shortage wound be repaired by the tranfered muscle tissue flap with the repair membrane covered; 53 cases underwent additional postoperative radiotherapy between 2-4 weeks and follow-up in 1, 3, 6, 12, 18, 24, 30, 36, 48, 60 months and observed the operation site repair process through the electronic laryngoscope, observed the patients respiration, swallow, phonation function.
  
  
  RESULTS
  Seventy-seven cases patients operation incision reached I phase healing standard, another 5 cases patients operation incision reached II phase healing standard because of the wound infection and fully-recovered through the local wound drainage,dressing process. All the patients tracheal cannula,the stomach tube be extubated successfully and without the local cicatricial constriction occurred. Seventy-eight cases follow up period reached 1 year including 53 cases who underwent postoperative radiotherapy, 49 cases follow up period reached 3 years including 32 cases who underwent postoperative radiotherapy, 14 cases follow up period reached 5 years including 12 cases who underwent postoperative radiotherapy. The patients with static local lesions discovered no reaction such as exclusion, allergy.
  
  
  CONCLUSIONS
  The application of xenogenic acellular dermal matrix membrane (or joint muscle flap transfer used in in the postoperative tissue shortage repair that after the head neck carcinoma resection have several advantage such as comparatively easily implementation, operation safety edge enough,well preserved organ function, comparatively low incidence about the laryngeal stenosis, the short-term and long-term repair effect are all exact.
authors.forename: Yanxia
authors.initials: Y
authors.lastname: Bai
authors.forename: Liying
authors.initials: L
authors.lastname: Yan
authors.forename: Shaoqiang
authors.initials: S
authors.lastname: Zhang
authors.forename: Yuan
authors.initials: Y
authors.lastname: Shao
authors.forename: Xiaobao
authors.initials: X
authors.lastname: Yao
authors.forename: Honghui
authors.initials: H
authors.lastname: Li
authors.forename: Ruimin
authors.initials: R
authors.lastname: Zhao
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhao
authors.forename: Pengfei
authors.initials: P
authors.lastname: Zhang
authors.forename: Qi
authors.initials: Q
authors.lastname: Yang
mesh_terms: D062088:Acellular Dermis; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D008297:Male; D009092:Mucous Membrane / Q000601:surgery; D011184:Postoperative Period; D000077195:Squamous Cell Carcinoma of Head and Neck; D013524:Surgical Flaps / Q000637:transplantation*; D014945:Wound Healing