title: Demyelinating disease: Is TOPIC the last trial for clinically isolated syndrome?
authors.affiliation: Multiple Sclerosis Center, 675 Nelson Rising Lane, Suite 221, Box 3206, San Francisco, CA 94158, USA.
authors.forename: Bruce A C
authors.initials: BA
authors.lastname: Cree
mesh_terms: D002986:Clinical Trials as Topic; D003437:Crotonates / Q000627:therapeutic use*; D003711:Demyelinating Diseases / Q000517:prevention & control*; D006801:Humans; D006885:Hydroxybutyrates; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000188:drug therapy*; D009570:Nitriles; D012008:Recurrence; D014052:Toluidines / Q000627:therapeutic use*
chemical_list: D003437:Crotonates; D006885:Hydroxybutyrates; D007166:Immunosuppressive Agents; D009570:Nitriles; D014052:Toluidines; C527525:teriflunomide