title: Methyl N-phenyl carbamate synthesis from aniline and methyl formate: carbon recycling to chemical products.
abstract: Methyl N-phenyl carbamate was synthesized from aniline by using methyl formate as a green and efficient carbonylating agent. High yields were obtained at milder reaction conditions compared to the conventional CO/CH3 OH route. Studies on the reaction sequence led to suggest an alternative and more efficient route to the carbamate via formanilide as intermediate.
authors.affiliation: CAT Catalytic Center, RWTH Aachen University, Worringerweg 2, 52074 Aachen (Germany).
authors.forename: Mohammad S
authors.initials: MS
authors.lastname: Yalfani
authors.forename: Giulio
authors.initials: G
authors.lastname: Lolli
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Müller
authors.forename: Aurel
authors.initials: A
authors.lastname: Wolf
authors.forename: Leslaw
authors.initials: L
authors.lastname: Mleczko
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D002219:Carbamates / Q000138:chemical synthesis*; D002244:Carbon / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D005563:Formic Acid Esters / Q000737:chemistry*; D055772:Green Chemistry Technology; D010084:Oxidation-Reduction; D059027:Recycling
chemical_list: D000814:Aniline Compounds; D002219:Carbamates; D005563:Formic Acid Esters; C025468:methyl formate; D002244:Carbon; C023650:aniline
keywords: aniline; carbamate; carbon recycling; methyl formate; oxidative carbonylation