title: Disseminated Bacille Calmette-Guerin (BCG) disease in an infant with severe combined immunodeficiency.
abstract: Bacille Calmette-Guerin (BCG) vaccine is administered to all newborns in countries where tuberculosis is still endemic. It is a live attenuated vaccine and considered quite safe in immunocompetent children. Disseminated BCG disease is the most serious complication seen only in individuals with underlying primary or secondary immunodeficiencies. We report a case of disseminated BCG disease in an infant with Severe Combined Immunodeficiency (SCID) who received BCG administration prior to diagnosis of SCID.
authors.affiliation: Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Shagufta
authors.initials: S
authors.lastname: Sohail
authors.affiliation: Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Afzal
authors.affiliation: Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Vaqas
authors.initials: V
authors.lastname: Anwar
authors.affiliation: Department of Paediatrics, Quaid-e-Azam International Hospital, Islamabad.
authors.forename: Quratulain
authors.initials: Q
authors.lastname: Shama
mesh_terms: D001500:BCG Vaccine / Q000009:adverse effects*; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D008297:Male; D009163:Mycobacterium bovis / Q000276:immunology / Q000472:pathogenicity*; D016511:Severe Combined Immunodeficiency / Q000150:complications* / Q000175:diagnosis; D014376:Tuberculosis / Q000382:microbiology / Q000517:prevention & control*; D014611:Vaccination / Q000009:adverse effects
chemical_list: D001500:BCG Vaccine