title: Ubiquitination as an efficient molecular strategy employed in salmonella infection.
abstract: The ubiquitin modification has various functions in the host innate immune system in response to the bacterial infection. To counteract the host immunity, Salmonella can specifically target ubiquitin pathways by its effector proteins. In this review, we describe the multiple facets of ubiquitin function during infection with Salmonella enterica Typhimurium and hypothesize how these studies on the host-pathogen interactions can help to understand the general function of the ubiquitination pathway in the host cell.
authors.affiliation: The Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University , Mississippi State, MS , USA.
authors.forename: Lakshmi A
authors.initials: LA
authors.lastname: Narayanan
authors.affiliation: The Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University , Mississippi State, MS , USA ; Institute for Genomics, Biocomputing and Biotechnology, Mississippi State University , Mississippi State, MS , USA.
authors.forename: Mariola J
authors.initials: MJ
authors.lastname: Edelmann
keywords: E3 ligases; Salmonella enterica Typhimurium; Salmonella-containing vacuole; autophagy; deubiquitinases; innate immune response; type III secretion system; ubiquitin