title: Hippocampus contributes to the maintenance but not the quality of visual information over time.
abstract: The hippocampus has recently been implicated in the brief representation of visual information, but its specific role is not well understood. We investigated this role using a paradigm that distinguishes quantity and quality of visual memory as described in a previous study. We found that amnesic patients with bilateral hippocampal damage (N = 5) were less likely to remember test stimuli than comparison participants despite a brief maintenance interval (900 msec). However, estimates of memory quality were similar for all groups. Our findings suggest that the hippocampus contributes to brief maintenance of visual information but does not contribute to the quality of that information.
authors.affiliation: Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA david-e-warren@uiowa.edu.
authors.forename: David E
authors.initials: DE
authors.lastname: Warren
authors.affiliation: Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA Department of Communications Sciences and Disorders, University of Iowa, Iowa City, Iowa 52242, USA.
authors.forename: Melissa C
authors.initials: MC
authors.lastname: Duff
authors.affiliation: Department of Psychology, University of Illinois at Urbana-Champaign, Champaign Illinois 61801, USA Beckman Institute, University of Illinois at Urbana-Champaign, Champaign Illinois 61801, USA Neuroscience Program, University of Illinois at Urbana-Champaign, Champaign Illinois 61801, USA.
authors.forename: Neal J
authors.initials: NJ
authors.lastname: Cohen
authors.affiliation: Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA Department of Psychology, University of Iowa, Iowa City, Iowa 52242, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Tranel
mesh_terms: D000647:Amnesia / Q000503:physiopathology* / Q000523:psychology; D005260:Female; D006624:Hippocampus / Q000502:physiology*; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D008875:Middle Aged; D008959:Models, Neurological; D008960:Models, Psychological; D009483:Neuropsychological Tests; D010775:Photic Stimulation; D013702:Temporal Lobe / Q000503:physiopathology; D014796:Visual Perception / Q000502:physiology*