title: Management of pregnant women infected with Ebola virus in a treatment centre in Guinea, June 2014.
abstract: We report two cases of confirmed Ebola virus disease in pregnant women, who presented at the Médecins Sans Frontières Ebola treatment centre in Guéckédou. Despite the very high risk of death, both pregnant women survived. In both cases the critical decision was made to induce vaginal delivery. We raise a number of considerations regarding the management of Ebola virus-infected pregnant women, including the place of amniocentesis and induced delivery, and whether certain invasive medical acts are justified.
authors.affiliation: Medecins Sans Frontieres - Operational Centre Brussels, Gueckedou, Guinea.
authors.forename: F M
authors.initials: FM
authors.lastname: Baggi
authors.forename: A
authors.initials: A
authors.lastname: Taybi
authors.forename: A
authors.initials: A
authors.lastname: Kurth
authors.forename: M
authors.initials: M
authors.lastname: Van Herp
authors.forename: A
authors.initials: A
authors.lastname: Di Caro
authors.forename: R
authors.initials: R
authors.lastname: Wölfel
authors.forename: S
authors.initials: S
authors.lastname: Günther
authors.forename: T
authors.initials: T
authors.lastname: Decroo
authors.forename: H
authors.initials: H
authors.lastname: Declerck
authors.forename: S
authors.initials: S
authors.lastname: Jonckheere
mesh_terms: D000328:Adult; D000649:Amniocentesis; D000998:Antiviral Agents / Q000627:therapeutic use; D036861:Delivery, Obstetric; D029043:Ebolavirus / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D016701:Guinea; D019142:Hemorrhagic Fever, Ebola / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000821:virology*; D011256:Pregnancy Outcome; D020133:Reverse Transcriptase Polymerase Chain Reaction; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents