title: Diffraction optical tomography using a quantitative phase imaging unit.
abstract: A simple and practical method to measure three-dimensional (3-D) refractive index (RI) distributions of biological cells is presented. A common-path self-reference interferometry consisting of a compact set of polarizers is attached to a conventional inverted microscope equipped with a beam scanning unit, which can precisely measure multiple 2-D holograms of a sample with high phase stability for various illumination angles, from which accurate 3-D optical diffraction tomograms of the sample can be reconstructed. 3-D RI tomograms of nonbiological samples such as polystyrene microspheres, as well as biological samples including human red blood cells and breast cancer cells, are presented.
authors.forename: Kyoohyun
authors.initials: K
authors.lastname: Kim
authors.forename: Zahid
authors.initials: Z
authors.lastname: Yaqoob
authors.forename: KyeoReh
authors.initials: K
authors.lastname: Lee
authors.forename: Jeon Woong
authors.initials: JW
authors.lastname: Kang
authors.forename: Youngwoon
authors.initials: Y
authors.lastname: Choi
authors.forename: Poorya
authors.initials: P
authors.lastname: Hosseini
authors.forename: Peter T C
authors.initials: PT
authors.lastname: So
authors.forename: YongKeun
authors.initials: Y
authors.lastname: Park
mesh_terms: D045744:Cell Line, Tumor; D004912:Erythrocytes / Q000166:cytology; D006801:Humans; D008853:Microscopy; D011137:Polystyrenes; D041622:Tomography, Optical / Q000379:methods*
chemical_list: D011137:Polystyrenes