title: Level of adherence and predictors of adherence to the Option B+ PMTCT programme in Tigray, northern Ethiopia.
abstract: OBJECTIVE
  The aim of this study was to determine the level of adherence to Option B+ PMTCT drugs and factors associated with adherence among HIV-positive pregnant women in public hospitals of Tigray, northern Ethiopia.
  
  
  METHODS
  A cross-sectional study was conducted among 277 HIV-positive pregnant women in 2014. A two-stage cluster sampling technique was used to select the study participants. Individual consent was obtained from each participant. Multivariate logistic regression was used to estimate the net effect sizes of factors associated with adherence to Option B+ PMTCT drugs.
  
  
  RESULTS
  The level of adherence of respondents to Option B+ PMTCT drugs was 87.1% (95% confidence interval (CI) 82.6-90.7%). Controlling for the effect of other factors, the odds of adhering to Option B+ PMTCT were 4.7 times higher among women who received counselling on medication as compared to those who did not (adjusted odds ratio (aOR) 4.7, 95% CI 1.98-11.35). Similarly, disclosing HIV status was positively associated with good adherence (aOR 4.2, 95% CI 1.07-16.33).
  
  
  CONCLUSIONS
  The adherence level was found to be reasonably good. Counselling on medication and HIV status disclosure were positive predictors of adherence to Option B+ PMTCT drugs.
authors.affiliation: Dr. Tewelde Legesse College of Health Sciences, PO Box 106, Mekelle, Ethiopia. Electronic address: hafebuy@yahoo.com.
authors.forename: Haftamu
authors.initials: H
authors.lastname: Ebuy
authors.affiliation: Department of Public Health, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.
authors.forename: Henock
authors.initials: H
authors.lastname: Yebyo
authors.affiliation: Department of Public Health, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.
authors.forename: Mussie
authors.initials: M
authors.lastname: Alemayehu
mesh_terms: D000328:Adult; D003376:Counseling; D003430:Cross-Sectional Studies; D030881:Disclosure; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission*; D006679:HIV Seropositivity / Q000453:epidemiology; D006801:Humans; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D016015:Logistic Models; D016017:Odds Ratio; D010349:Patient Compliance; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Adherence; HIV-positive women; Option B+ PMTCT; Tigray