title: Emergence of a KPC-3-Producing Escherichia coli ST69 as a Cause of Bloodstream Infections in Italy.
abstract: The spread of carbapenem-resistant gram negatives is a global emergency, and surveillance of new resistant clones is critical from both public health and clinical standpoints. Herein, we describe the emergence of a KPC-3-producing Escherichia coli ST69 as a cause of bloodstream infection in two Italian patients.
authors.affiliation: 1Infectious Diseases Unit, IRCCS San Martino University Hospital-IST, University of Genoa, Genoa, Italy.
authors.forename: Daniele Roberto
authors.initials: DR
authors.lastname: Giacobbe
authors.affiliation: 1Infectious Diseases Unit, IRCCS San Martino University Hospital-IST, University of Genoa, Genoa, Italy.
authors.forename: Valerio
authors.initials: V
authors.lastname: Del Bono
authors.affiliation: 2Microbiology Unit DISC, IRCCS San Martino University Hospital-IST, University of Genoa, Genoa, Italy.
authors.forename: Erika
authors.initials: E
authors.lastname: Coppo
authors.affiliation: 2Microbiology Unit DISC, IRCCS San Martino University Hospital-IST, University of Genoa, Genoa, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Marchese
authors.affiliation: 1Infectious Diseases Unit, IRCCS San Martino University Hospital-IST, University of Genoa, Genoa, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Viscoli
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology; D002939:Ciprofloxacin / Q000627:therapeutic use; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D004927:Escherichia coli Infections / Q000188:drug therapy* / Q000382:microbiology; D015870:Gene Expression; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D007558:Italy; D008297:Male; D008826:Microbial Sensitivity Tests; D008911:Minocycline / Q000031:analogs & derivatives / Q000627:therapeutic use; D000078304:Tigecycline; D016896:Treatment Outcome; D018440:beta-Lactam Resistance / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D002939:Ciprofloxacin; D000078304:Tigecycline; D001618:beta-Lactamases; D008911:Minocycline