title: [Leiomyosarcoma of the prostate treated with neoadjuvant intra-arterial chemotherapy and pelvic excenteration ; a case report].
abstract: A 34-year-old man presented with left inguinal discomfort. Digital rectal examination revealed an enlarged nodular prostate. Computed tomography showed an enlarged prostate invading the bladder and rectum. A histological examination of transrectal prostatic needle biopsy specimens revealed sarcoma of the prostate. He received three courses of neoadjuvant arterial injection chemotherapy consisting of adriamycin (30 mg/m2) and cisplatin (70 mg/m2). Total pelvic excenteration was perfomed. Histopathological examination of the tumor revealed leiomyosarcoma of the prostate. He remains alive 11 months after the operation without recurrence.
authors.affiliation: The Department of Urology, Hirosaki Univerity Graduate School of Medicine.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Noro
authors.affiliation: The Department of Urology, Hirosaki Univerity Graduate School of Medicine.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Yoneyama
authors.affiliation: The Department of Urology, Hirosaki Univerity Graduate School of Medicine.
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Hagiwara
authors.affiliation: The Department of Urology, Hirosaki Univerity Graduate School of Medicine.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Mori
authors.affiliation: The Department of Urology, Hirosaki Univerity Graduate School of Medicine.
authors.forename: Hayato
authors.initials: H
authors.lastname: Yamamoto
authors.affiliation: The Department of Urology, Hirosaki Univerity Graduate School of Medicine.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Hashimoto
authors.affiliation: The Department of Urology, Hirosaki Univerity Graduate School of Medicine.
authors.forename: Takuya
authors.initials: T
authors.lastname: Koie
authors.affiliation: The Department of Urology, Hirosaki Univerity Graduate School of Medicine.
authors.forename: Chikara
authors.initials: C
authors.lastname: Ohyama
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001706:Biopsy; D002945:Cisplatin / Q000008:administration & dosage; D051517:Digital Rectal Examination; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007269:Injections, Intra-Arterial; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D008297:Male; D020360:Neoadjuvant Therapy; D010385:Pelvic Exenteration; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D004317:Doxorubicin; D002945:Cisplatin