title: Trends in antimicrobial resistance in Neisseria gonorrhoeae isolated from Guangzhou, China, 2000 to 2005 and 2008 to 2013.
abstract: A total of 1224 Neisseria gonorrhoeae isolates from Guangzhou in 2 periods (2000-2005 and 2008-2013) were subjected to antimicrobial susceptibility testing. The percentage of penicillin- and ciprofloxacin-resistant isolates increased from 71.1% (473/665) to 90.9% (508/559) and 88.9% (591/665) to 98.0% (548/559), respectively. All isolates remain susceptible to spectinomycin and ceftriaxone, with increasing minimum inhibitory concentrations.
authors.affiliation: From the *Institute of Dermatology, Guangzhou Medical University, Guangzhou, PR China; and †Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, PR China.
authors.forename: Wen-Ling
authors.initials: WL
authors.lastname: Cao
authors.forename: Jing-Yao
authors.initials: JY
authors.lastname: Liang
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Li
authors.forename: Chao
authors.initials: C
authors.lastname: Bi
authors.forename: Ri-Dong
authors.initials: RD
authors.lastname: Yang
authors.forename: Yan-Hua
authors.initials: YH
authors.lastname: Liang
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.forename: Dao-Qing
authors.initials: DQ
authors.lastname: Zhong
authors.forename: Xing-Dong
authors.initials: XD
authors.lastname: Ye
authors.forename: Xi-Bao
authors.initials: XB
authors.lastname: Zhang
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002443:Ceftriaxone / Q000494:pharmacology; D002681:China; D002939:Ciprofloxacin / Q000494:pharmacology; D024881:Drug Resistance, Bacterial / Q000187:drug effects*; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009344:Neisseria gonorrhoeae / Q000187:drug effects*; D010406:Penicillins / Q000494:pharmacology; D000198:Spectinomycin / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D002939:Ciprofloxacin; D002443:Ceftriaxone; D000198:Spectinomycin