title: [Neonatal hypoxic-ischemic brain injury: pathogenesis and neuropathology].
abstract: The perinatal period represents a clinical setting of potential risk for injury to developing brain secondary to many causes, with the chance for long-lasting, profound neurocognitive deficits. Neonatal hypoxic-ischemic brain injury leads to serious long-term morbidities. The leading pathogenetic mechanisms are hypoxia and/or ischemia, as a result of perinatal asphyxia. Understanding of the underlying pathophysiology will help the physicians in the general supportive management and neuroprotection of the neonatal brain.
authors.forename: P
authors.initials: P
authors.lastname: Radulova
authors.forename: B
authors.initials: B
authors.lastname: Slancheva
mesh_terms: D001921:Brain / Q000473:pathology / Q000503:physiopathology*; D001930:Brain Injuries / Q000150:complications / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000150:complications / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology*; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology / Q000473:pathology / Q000503:physiopathology*