title: Development of therapeutics for treatment of Ebola virus infection.
abstract: Ebola virus infection can cause Ebola virus disease (EVD). Patients usually show severe symptoms, and the fatality rate can reach up to 90%. No licensed medicine is available. In this review, development of therapeutics for treatment of Ebola virus infection and EVD will be discussed.
authors.affiliation: Key Lab of Medical Molecular Virology of MOE/MOH, Shanghai Medical College, Fudan University, 130 Dong An Rd., Xuhui District, Shanghai 200032, China.
authors.forename: Haoyang
authors.initials: H
authors.lastname: Li
authors.affiliation: Key Lab of Medical Molecular Virology of MOE/MOH, Shanghai Medical College, Fudan University, 130 Dong An Rd., Xuhui District, Shanghai 200032, China.
authors.forename: Tianlei
authors.initials: T
authors.lastname: Ying
authors.affiliation: Key Lab of Medical Molecular Virology of MOE/MOH, Shanghai Medical College, Fudan University, 130 Dong An Rd., Xuhui District, Shanghai 200032, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Yu
authors.affiliation: Key Lab of Medical Molecular Virology of MOE/MOH, Shanghai Medical College, Fudan University, 130 Dong An Rd., Xuhui District, Shanghai 200032, China. Electronic address: lul@fudan.edu.cn.
authors.forename: Lu
authors.initials: L
authors.lastname: Lu
authors.affiliation: Key Lab of Medical Molecular Virology of MOE/MOH, Shanghai Medical College, Fudan University, 130 Dong An Rd., Xuhui District, Shanghai 200032, China; Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA. Electronic address: shibojiang@fudan.edu.cn.
authors.forename: Shibo
authors.initials: S
authors.lastname: Jiang
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology / Q000627:therapeutic use*; D046129:Ebola Vaccines / Q000627:therapeutic use; D029043:Ebolavirus / Q000187:drug effects / Q000235:genetics; D019142:Hemorrhagic Fever, Ebola / Q000188:drug therapy* / Q000517:prevention & control / Q000821:virology; D006801:Humans; D012367:RNA, Viral / Q000096:biosynthesis / Q000187:drug effects / Q000235:genetics; D053586:Virus Internalization / Q000187:drug effects
chemical_list: D000998:Antiviral Agents; D046129:Ebola Vaccines; D012367:RNA, Viral
keywords: Antibody; Ebola virus; Ebola virus disease; Small-molecule compounds; Therapeutics; Treatment