title: Clinical course of focal choroidal excavation in Vogt-Koyanagi-Harada disease.
abstract: We describe focal choroidal excavation (FCE) in a case of Vogt-Koyanagi-Harada (VKH) disease and compare the findings with different chorioretinal conditions. A 55-year-old man was diagnosed with VKH based on panuveitis and exudative retinal detachments. Spectral-domain optical coherence tomography demonstrated a dome-shaped protrusion with a nonconforming pattern at the fovea, which had been detected as a conforming pattern 1 year before the onset. The FCE pattern returned into a conforming pattern following corticosteroid therapy. These findings suggest that the natively existent FCE could be affected by pathophysiological changes of VKH as well as other chorioretinal conditions.
authors.affiliation: Department of Ophthalmology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan ; Laboratory of Visual Physiology, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan ; Department of Ophthalmology, Osaka Medical College, Takatsuki, Osaka, Japan.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Nishikawa
authors.affiliation: Department of Ophthalmology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan ; Laboratory of Visual Physiology, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan ; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan ; UCL Institute of Ophthalmology, London, UK.
authors.forename: Kaoru
authors.initials: K
authors.lastname: Fujinami
authors.affiliation: Department of Ophthalmology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan ; Laboratory of Visual Physiology, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Watanabe
authors.affiliation: Department of Ophthalmology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan ; Laboratory of Visual Physiology, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Noda
authors.affiliation: Department of Ophthalmology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan ; Laboratory of Visual Physiology, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan.
authors.forename: Kazushige
authors.initials: K
authors.lastname: Tsunoda
authors.affiliation: Department of Ophthalmology, National Hospital Organization, Tokyo Medical Center, Tokyo, Japan ; Laboratory of Visual Physiology, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan.
authors.forename: Kunihiko
authors.initials: K
authors.lastname: Akiyama
keywords: Vogt–Koyanagi–Harada disease; choroidal excavation; focal choroidal excavation; optical coherence tomography