title: Size of cervical lymph node and metastasis in squamous cell carcinoma of the oral tongue and floor of mouth.
abstract: BACKGROUND
  Squamous cell carcinoma (SCC) of the oral tongue and floor of mouth are the most common head and neck cancers. Regional metastasis of SCC is most likely found at the cervical lymph node. Size and characteristics of pathologically suspicious lymph nodes are related to the aggressiveness of the primary tumor: The objective of this study is to analyze the conrrelation between sizes of cervical node and metastasis in SCC of oral tongue and floor of mouth.
  
  
  METHODS
  Retrospective review was conducted firom the patient's charts between January 2008 and December 2012. Clinical, histopathology and surgical records were reviewed. Cervical lymph nodes ofSCC of oral tongue and floor of mouth were reviewed and divided into four groups depending on their size (1-5 mm, 6-9 mm, 10-30 mm and more than 30 am,). A p-value <0.05 was considered statistically significant.
  
  
  RESULTS
  196 patients with SCC of the oral cavity were recorded. Sixteen patients ofSCC of the oral tongue and 15patients of SCC of the floor of mouth underwent neck dissection (641 cervical nodes). Most ofthe patients were diagnosed with stage 3 (41.94%). Extracapsular extension was found in 72.15% of SCC of oral tongue and 73.33 % of SCC ofthe floor of mouth. Size of cervical lymph nodes less than 10 mm was found to be metastasis at 9.27% and 10.82% of SCC of oral tongue and floor of mouth, respectively.
  
  
  CONCLUSIONS
  Cervical node metastasis can be found in SCC of the oral tongue and floor ofmouth with clinlically negative node andsize of cervical node less than 10 mm. Here in, size of cervical node less than 10 mm was still important due to the chance for metastasis especially high grade tumors, advanced stage cancer and lymphovascular invasion.
authors.forename: Weerawut
authors.initials: W
authors.lastname: Jarungroongruangchai
authors.forename: Mongkol
authors.initials: M
authors.lastname: Charoenpitakchai
authors.forename: Tawatchai
authors.initials: T
authors.lastname: Silpeeyodom
authors.forename: Chatchai
authors.initials: C
authors.lastname: Pruksapong
authors.forename: Chairat
authors.initials: C
authors.lastname: Burusapat
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor / Q000473:pathology; D009062:Mouth Neoplasms / Q000453:epidemiology / Q000473:pathology*; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D019647:Oral Surgical Procedures; D012189:Retrospective Studies; D013785:Thailand / Q000453:epidemiology; D014059:Tongue / Q000473:pathology