title: Pleuritis clinically diagnosed as aspergillosis during the course of microscopic polyangiitis.
abstract: Pleural aspergillosis is a rare fungal infection. We herein report a case of pleuritis clinically diagnosed as aspergillosis without apparent Aspergillus lung lesions. A 75-year-old man receiving immunosuppressive therapy due to microscopic polyangiitis was admitted for treatment of massive pleural effusion. Histology of the parietal pleura revealed septate hyphae. In addition, a hematological marker of Aspergillus indicated Aspergillus pleuritis. The pleural effusion resolved after administration of the voriconazole. The trigger for invasion of Aspergillus into the pleura was thought to be spontaneous pneumothorax, which had occurred five months earlier.
authors.affiliation: Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Japan.
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Kimoto
authors.forename: Kensuke
authors.initials: K
authors.lastname: Oryoji
authors.forename: Ayumi
authors.initials: A
authors.lastname: Uchino
authors.forename: Shigeru
authors.initials: S
authors.lastname: Yoshizawa
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Niiro
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsukamoto
authors.forename: Takahiko
authors.initials: T
authors.lastname: Horiuchi
mesh_terms: D000368:Aged; D001230:Aspergillus / Q000302:isolation & purification*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008297:Male; D055953:Microscopic Polyangiitis / Q000150:complications* / Q000188:drug therapy; D010996:Pleural Effusion / Q000175:diagnosis / Q000382:microbiology*; D010998:Pleurisy / Q000382:microbiology*; D055732:Pulmonary Aspergillosis / Q000175:diagnosis* / Q000382:microbiology*
chemical_list: D007166:Immunosuppressive Agents