title: Blood HCO3- concentration predicts the long-term prognosis of acute kidney injury patients.
abstract: OBJECTIVE
  To evaluate the value of HCO3(-) concentrations in long-term prognosis after acute kidney injury.
  
  
  METHODS
  A total of 169 AKI patients were included in this study. At the 12-month follow-up, the patients were divided into recovered and unrecovered groups.
  
  
  RESULTS
  The blood HCO3(-) concentrations were significantly correlated with poor prognosis. The area under the curve for renal prognosis of 6 months later blood HCO3(-) concentrations was 0.798. Combined HCO3(-) and Scr level area under the curve was 0.952.
  
  
  CONCLUSIONS
  The blood HCO3(-) level was useful in evaluating renal prognosis of acute kidney injury patients. The combination of blood HCO3(-) concentration and Scr level increased the accuracy of prediction.
authors.affiliation: Department of Nephrology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, PR China.
authors.forename: Xiajing
authors.initials: X
authors.lastname: Che
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Xie
authors.forename: Chunlin
authors.initials: C
authors.lastname: Wang
authors.forename: Qin
authors.initials: Q
authors.lastname: Wang
authors.forename: Minfang
authors.initials: M
authors.lastname: Zhang
authors.forename: Chaojun
authors.initials: C
authors.lastname: Qi
authors.forename: Zhaohui
authors.initials: Z
authors.lastname: Ni
authors.forename: Shan
authors.initials: S
authors.lastname: Mou
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood* / Q000175:diagnosis; D000328:Adult; D001639:Bicarbonates / Q000097:blood*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011379:Prognosis; D055815:Young Adult
chemical_list: D001639:Bicarbonates
keywords: Cox regression analysis; Kaplan–Meier method; acute kidney injury (AKI); blood HCO3 - concentration; combined markers; follow-up; prevention; receiver operating characteristic–area under the curve; renal prognosis