title: Anthropometric assessment of a Middle Eastern group of autistic children.
abstract: BACKGROUND
  Growth abnormalities are uniquely associated with autism spectrum disorders (ASD); however, the extent to which growth abnormalities are present has hardly been investigated. The current study aims to compare the differences in anthropometric parameters in a group of autistic Egyptian children and the healthy normal population.
  
  
  METHODS
  We recruited 100 children with ASD from the Outpatient Clinic for "Autistic Children" at the Medical Research Hospital of Excellence, National Research Centre in Cairo, Egypt. They were diagnosed by DSM-IV criteria of the American Psychiatric Association, Autism Diagnostic Interview-Revised, and Childhood Autism Rating Scale. Of these children at age of 3-10 years, 71 were males and 29 females. Eight anthropometric parameters were assessed in view of data of the healthy Egyptians of pertinent sex and age.
  
  
  RESULTS
  Weight and body mass index increased because of a significant increase in subcutaneous fat thickness. This tendency with a probable decrease in muscle mass was more evident in male or in older children, likely resulting from sedentary life style and food selectivity.
  
  
  CONCLUSIONS
  The Z head circumference score and its variance significantly increased especially in males or older children, suggesting the relative overgrowth of the brain in a substantial percentage of Egyptian children with autism. We concluded that increased fat composition in Egyptian autistic children with decreased muscle mass necessitates tailoring a specially designed food supplementation program to ameliorate the severity of autism symptoms.
authors.affiliation: Department of Research on Children with Special Needs, National Research Centre (NRC), Cairo, Egypt, meguidna@yahoo.com.
authors.forename: Nagwa A
authors.initials: NA
authors.lastname: Meguid
authors.forename: Wafaa A
authors.initials: WA
authors.lastname: Kandeel
authors.forename: Khaled E
authors.initials: KE
authors.lastname: Wakeel
authors.forename: Aly A
authors.initials: AA
authors.lastname: El-Nofely
mesh_terms: D000886:Anthropometry; D001321:Autistic Disorder / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D004534:Egypt; D005260:Female; D006801:Humans; D008297:Male; D010641:Phenotype