title: Chest wall and rib irradiation and toxicities of early-stage lung cancer patients treated with CyberKnife stereotactic body radiotherapy.
abstract: OBJECTIVE
  The aim of the study is to evaluate the chest wall and rib toxicities in primary lung cancer patients treated with CyberKnife-based stereotactic body radiotherapy.
  
  
  METHODS
  In this study, data were collected from the 118 patients, of which 25 patients who had longer follow-up (mean: 21.9 months) were considered. Studied parameters were maximum point dose, doses to 1-100 cm(3) of chest wall and 1-10 cm(3) of ribs.
  
  
  RESULTS
  Three patients developed chest wall pain (grade I). 25 studied patients, on average, received 27.7 Gy to 30 cm(3) of chest wall and 50.4 Gy to 1 cm(3) of rib. Nine patients had more than 30 Gy dose to 30 cm(3) of chest wall. No rib bone fracture was found.
  
  
  CONCLUSIONS
  No correlations of chest wall pain and volume of irradiation were found.
authors.affiliation: Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Western Reserve University, 11100 Euclid Avenue, LTR B181, Cleveland, OH 44106, USA.
authors.forename: Tarun
authors.initials: T
authors.lastname: Podder
authors.forename: Tithi
authors.initials: T
authors.lastname: Biswas
authors.forename: Min
authors.initials: M
authors.lastname: Yao
authors.forename: Yuxia
authors.initials: Y
authors.lastname: Zhang
authors.forename: Ellen
authors.initials: E
authors.lastname: Kim
authors.forename: Rodney J
authors.initials: RJ
authors.lastname: Ellis
authors.forename: Simon S
authors.initials: SS
authors.lastname: Lo
authors.forename: Mitchell
authors.initials: M
authors.lastname: Machtay
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000453:epidemiology / Q000209:etiology; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000453:epidemiology* / Q000209:etiology; D016634:Radiosurgery / Q000009:adverse effects*; D012189:Retrospective Studies; D012272:Ribs / Q000473:pathology / Q000528:radiation effects; D035441:Thoracic Wall / Q000473:pathology / Q000528:radiation effects
keywords: CyberKnife; chest pain; chest wall toxicity; rib fracture; stereotactic body radiotherapy