title: Collaterals in endovascular therapy for stroke.
abstract: OBJECTIVE
  Endovascular therapy is a promising aspect of acute ischemic stroke treatment. The ideal population of patients who benefit from treatment remains undefined, and the status of collateral circulation at presentation may be a key feature in their identification.
  
  
  RESULTS
  Adequate collateral flow has been recently demonstrated to be associated with improved clinical status on presentation, increased likelihood of recanalization with endovascular therapy, and better functional outcome at 3 months.
  
  
  CONCLUSIONS
  In this review, we define the collateral circulation, review methods of its measurement, and present recent clinical data on its impact in endovascular therapy for acute ischemic stroke. We outline our current understandings and discuss their relevance in future directions with clinical stroke management.
authors.affiliation: aDivision of Interventional Neuroradiology, Department of Radiology bNeurovascular Imaging Research Core, Department of Neurology, University of California Los Angeles, Los Angeles, California, USA.
authors.forename: Sunil A
authors.initials: SA
authors.lastname: Sheth
authors.forename: David S
authors.initials: DS
authors.lastname: Liebeskind
mesh_terms: D002545:Brain Ischemia / Q000628:therapy*; D003097:Collateral Circulation / Q000502:physiology*; D057510:Endovascular Procedures; D006801:Humans; D011379:Prognosis; D020521:Stroke / Q000628:therapy*; D015912:Thrombolytic Therapy / Q000379:methods*