title: [Case of portal venous gas and pneumatosis cystoides intestinalis occurring during chemotherapy for a castration-resistant prostate cancer].
abstract: Portal venous gas is a rare complication. We present a case of hepatic portal venous gas (HPVG) and pneumatosis cystoides intestinalis (PCI) in a patient treated with docetaxel for prostate cancer. An 80-year-old man with castration-resistant prostate cancer received 5 cycles of docetaxel. Diarrhea and vomiting appeared on the 4th day of the 5th cycle. An abdominal computed tomography (CT) scan revealed HPVG and PCI. Since there were neither peritoneal irritation signs nor intestinal necrosis, we performed conservative management. The HPVG and PCI were no longer detected in the abdominal CT scan on the 18th day. Mucosal injury of the bowel wall by docetaxel might have caused HPVG and PCI. This case report is the first description of HPVG and PCI in a patient with castration-resistant prostate cancer in Japan.
authors.affiliation: The Department of Urology, Yamato Municipal Hospital.
authors.forename: Makoto
authors.initials: M
authors.lastname: Iwasaki
authors.affiliation: The Department of Urology, Yamato Municipal Hospital.
authors.forename: Kazuto
authors.initials: K
authors.lastname: Okajima
authors.affiliation: The Department of Urology, Yamato Municipal Hospital.
authors.forename: Tetsuzo
authors.initials: T
authors.lastname: Takano
authors.affiliation: The Department of Urology, Yamato Municipal Hospital.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Misaki
mesh_terms: D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000009:adverse effects*; D003664:Decompression / Q000379:methods; D000077143:Docetaxel; D004618:Embolism, Air / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D011006:Pneumatosis Cystoides Intestinalis / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000628:therapy; D011169:Portal Vein; D064129:Prostatic Neoplasms, Castration-Resistant / Q000188:drug therapy*; D011859:Radiography; D043823:Taxoids / Q000009:adverse effects*
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D043823:Taxoids; D000077143:Docetaxel