title: From anilines to isatins: oxidative palladium-catalyzed double carbonylation of C-H bonds.
abstract: A novel palladium-catalyzed C-H double carbonylation introduces two adjacent carbonyl groups for the synthesis of isatins from readily available anilines. The reaction proceeds under atmospheric pressure of CO with high regioselectivity and without any additives. Density functional theory investigations indicate that the palladium-catalyzed double carbonylation catalytic cycle is plausible.
authors.affiliation: College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, Hubei (P.R. China) http://aiwenlei.whu.edu.cn/Main_Website/
authors.forename: Wu
authors.initials: W
authors.lastname: Li
authors.forename: Zhengli
authors.initials: Z
authors.lastname: Duan
authors.forename: Xueye
authors.initials: X
authors.lastname: Zhang
authors.forename: Heng
authors.initials: H
authors.lastname: Zhang
authors.forename: Mengfan
authors.initials: M
authors.lastname: Wang
authors.forename: Ru
authors.initials: R
authors.lastname: Jiang
authors.forename: Hongyao
authors.initials: H
authors.lastname: Zeng
authors.forename: Chao
authors.initials: C
authors.lastname: Liu
authors.forename: Aiwen
authors.initials: A
authors.lastname: Lei
keywords: CH activation; carbonylation; heterocycles; oxidation; palladium