title: Female patient-specific finite element modeling of pelvic organ prolapse (POP).
abstract: Pelvic organ prolapse (POP) occurs only in women and becomes more common as women age. However, the surgical practices remain poorly evaluated. The realization of a simulator of the dynamic behavior of the pelvic organs is then identified as a need. It allows the surgeon to estimate the functional impact of his actions before his implementation. In this work, the simulation will be based on a patient-specific approach in which each geometrical model will be carried out starting from magnetic resonance image (MRI) acquisition of pelvic organs of one patient. To determine the strain and stress in the soft biological tissues, hyperelastic constitutive laws are used in the context of finite element analysis. The Yeoh model has been implemented into an in-house finite element code FER to model these organ tissues taking into account large deformations with multiple contacts. The 2D and 3D models are considered in this preliminary study and the results show that our method can help to improve the understanding of different forms of POP.
authors.affiliation: Laboratoire de Mécanique et d׳Energétique d'Évry, Université d'Évry-Val d׳Essonne, Évry, France.
authors.forename: Zhuo-Wei
authors.initials: ZW
authors.lastname: Chen
authors.affiliation: Laboratoire de Mécanique et d׳Energétique d'Évry, Université d'Évry-Val d׳Essonne, Évry, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Joli
authors.affiliation: Laboratoire de Mécanique et d׳Energétique d'Évry, Université d'Évry-Val d׳Essonne, Évry, France; School of Mechanics and Engineering, Southwest Jiaotong University, Chengdu, China. Electronic address: feng@ufrst.univ-evry.fr.
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Feng
authors.affiliation: Laboratoire des Sciences de l׳Information et des Systèmes, Marseille, France.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Rahim
authors.affiliation: Service de Chirurgie Digestive, Hôpital la Timone, Marseille, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Pirró
authors.affiliation: Laboratoire des Sciences de l׳Information et des Systèmes, Marseille, France.
authors.forename: Marc-Emmanuel
authors.initials: ME
authors.lastname: Bellemare
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D005260:Female; D020342:Finite Element Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods; D055595:Mechanical Phenomena; D008875:Middle Aged; D066230:Patient-Specific Modeling; D056887:Pelvic Organ Prolapse; D013314:Stress, Mechanical
keywords: Deformation; Finite element method; Hyperelasticity; Pelvic organ prolapse; Soft tissue