title: Comparative study of surface-active properties and antimicrobial activities of disaccharide monoesters.
abstract: The objective of this research was to determine the effect of sugar or fatty acid in sugar ester compounds on the surface-active properties and antimicrobial activities of these compounds. Disaccharides of medium-chain fatty acid monoesters were synthesized through transesterifications by immobilized lipase (Lipozyme TLIM) to yield nine monoesters for subsequent study. Their antimicrobial activities were investigated using three pathogenic microorganisms: Staphylococcus aureus, Escherichia coli O157:H7 and Candida albicans. Their surface-active properties including air-water surface tension, critical micelle concentration, and foaming and emulsion power and stability were also studied. The results showed that all of the tested monoesters were more effective against Staphylococcus aureus (Gram-positive bacterium) than against Escherichia coli O157:H7 (Gram-negative bacterium). The results demonstrated that the carbon chain length was the most important factor influencing the surface properties, whereas degree of esterification and hydrophilic groups showed little effect.
authors.affiliation: College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, Zhejiang, China; Yunnan Collage of Traditional Chinese Medicine, Kunming, Yunnan, China; Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang, China.
authors.forename: Xi
authors.initials: X
authors.lastname: Zhang
authors.affiliation: College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, Zhejiang, China; Beijing Institute of Nutrition, Synutra International Inc., Beijing, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Song
authors.affiliation: College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, Zhejiang, China; Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang, China.
authors.forename: Maierhaba
authors.initials: M
authors.lastname: Taxipalati
authors.affiliation: College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, Zhejiang, China; Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.affiliation: College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, Zhejiang, China; Zhejiang Key Laboratory for Agro-Food Processing, Zhejiang University, Hangzhou, Zhejiang, China; Fuli Institute of Food Science, Zhejiang University, Hangzhou, Zhejiang, China.
authors.forename: Fengqin
authors.initials: F
authors.lastname: Feng
mesh_terms: D000388:Air; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D004187:Disaccharides / Q000737:chemistry* / Q000494:pharmacology; D004355:Drug Stability; D004800:Enzymes, Immobilized / Q000737:chemistry / Q000378:metabolism; D019453:Escherichia coli O157 / Q000187:drug effects; D004952:Esters; D008049:Lipase / Q000737:chemistry / Q000378:metabolism; D008823:Micelles; D008826:Microbial Sensitivity Tests; D013211:Staphylococcus aureus / Q000187:drug effects; D013500:Surface Tension; D013816:Thermodynamics; D014867:Water / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D004187:Disaccharides; D004800:Enzymes, Immobilized; D004952:Esters; D008823:Micelles; D014867:Water; D008049:Lipase