title: An unusual presentation of endobronchial Hodgkin's lymphoma.
abstract: Endobronchial involvement of Hodgkin's lymphoma is a rare presentation of the disease. However, it needs to be considered in patients presenting with non-resolving pneumonia in the setting of Hodgkin's disease. In such cases, clinicians need to ensure adequate and multiple biopsies as patients may have co-existent pulmonary infection and disease involvement. A 16 years old patient reported with a history of relapsed Hodgkin's disease, with bilateral pulmonary infiltrates, that failed to resolve after empiric antibiotic therapy. Positron Emission Tomography (PET) scan was performed demonstrating equivocal uptake in left upper lobe. Bronchoscopy revealed a necrotic endobronchial mass. Initial biopsy only revealed necrotic inflammatory debris, however, since the patient continued to lose weight, repeat biopsy was performed which demonstrated CD 30 positive Hodgkin's lymphoma cells.
authors.affiliation: Department of Internal Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore.
authors.forename: Shazia
authors.initials: S
authors.lastname: Awan
authors.affiliation: Department of Internal Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Center, Lahore.
authors.forename: Ali Saeed
authors.initials: AS
authors.lastname: Wahla
mesh_terms: D000293:Adolescent; D001706:Biopsy; D001984:Bronchial Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D001999:Bronchoscopy; D005260:Female; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D011014:Pneumonia / Q000175:diagnosis / Q000209:etiology*; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed