title: A comparison of high viscosity bone cement and low viscosity bone cement vertebroplasty for severe osteoporotic vertebral compression fractures.
abstract: OBJECTIVE
  To compare the clinical outcome and complications of high viscosity and low viscosity poly-methyl methacrylate bone cement PVP for severe OVCFs.
  
  
  METHODS
  From December 2010 to December 2012, 32 patients with severe OVCFs were randomly assigned to either group H using high viscosity cement (n=14) or group L using low viscosity cement (n=18). The clinical outcomes were assessed by the Visual Analog Scale (VAS), Oswestry Disability Index (ODI), Short Form-36 General Health Survey (SF-36), kyphosis Cobb's angle, vertebral height, and complications.
  
  
  RESULTS
  Significant improvement in the VAS, ODI, SF-36 scores, kyphosis Cobb's angle, and vertebral height were noted in both the groups, and there were no significant differences between the two groups. Cement leakage was seen less in group H. Postoperative assessment using computed tomography identified cement leakage in 5 of 17 (29.4%) vertebrae in group H and in 15 of 22 (68.2%) vertebrae in group L (P=0.025).
  
  
  CONCLUSIONS
  The PVP using high viscosity bone cement can provide the same clinical outcome and fewer complications compared with PVP using low viscosity bone cement.
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China.
authors.forename: Jingcheng
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China. Electronic address: 17374769@qq.com.
authors.forename: Xinmin
authors.initials: X
authors.lastname: Feng
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China.
authors.forename: Yuping
authors.initials: Y
authors.lastname: Tao
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China.
authors.forename: Jiandong
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China.
authors.forename: Yongxiang
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China.
authors.forename: Shengfei
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Cai
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei People's Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, Jiangsu 225001, China.
authors.forename: Jijun
authors.initials: J
authors.lastname: Huang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001843:Bone Cements / Q000627:therapeutic use*; D005260:Female; D050815:Fractures, Compression / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D058866:Osteoporotic Fractures / Q000601:surgery*; D011184:Postoperative Period; D054854:Vertebroplasty / Q000379:methods; D014783:Viscosity
chemical_list: D001843:Bone Cements
keywords: Bone cement; Leakage; Severe osteoporotic vertebral compression fractures; Vertebroplasty; Viscosity