title: Bortezomib-induced acute pancreatitis: Case report and review of the literature.
abstract: Acute pancreatitis is a rare complication of chemotherapy agents. We describe the case of a patient with multiple myeloma who developed acute pancreatitis after treatment with bortezomib, a proteasome inhibitor commonly used in the treatment of this disease. We reviewed the available medical literature on this topic, and found other seven similar cases, all after intravenous bortezomib. Our case is the first one occurring with the subcutaneous route of administration.
authors.affiliation: Penn State Milton S. Hershey Medical Center, Hershey, USA gtalamo@hmc.psu.edu.
authors.forename: Giampaolo
authors.initials: G
authors.lastname: Talamo
authors.affiliation: Penn State Milton S. Hershey Medical Center, Hershey, USA.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Sivik
authors.affiliation: Penn State Milton S. Hershey Medical Center, Hershey, USA.
authors.forename: Manoj K
authors.initials: MK
authors.lastname: Pandey
authors.affiliation: Penn State Milton S. Hershey Medical Center, Hershey, USA.
authors.forename: Muhammad A
authors.initials: MA
authors.lastname: Mir
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000069286:Bortezomib / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009101:Multiple Myeloma / Q000175:diagnosis / Q000188:drug therapy; D010195:Pancreatitis / Q000139:chemically induced* / Q000175:diagnosis*; D061988:Proteasome Inhibitors / Q000009:adverse effects*
chemical_list: D000970:Antineoplastic Agents; D061988:Proteasome Inhibitors; D000069286:Bortezomib
keywords: Bortezomib; acute pancreatitis; proteasome inhibitors