title: Automated structure determination from NMR spectra.
abstract: Three-dimensional structures of proteins in solution can be calculated on the basis of conformational restraints derived from NMR measurements. This chapter gives an overview of the computational methods for NMR protein structure analysis highlighting recent automated methods for the assignment of NMR spectra, the collection of conformational restraints, and the structure calculation.
authors.affiliation: Institute of Biophysical Chemistry, Center for Biomolecular Magnetic Resonance, Max-von-Laue-Str. 9, 60438, Frankfurt am Main, Germany.
authors.forename: Elena
authors.initials: E
authors.lastname: Schmidt
authors.forename: Peter
authors.initials: P
authors.lastname: Güntert
mesh_terms: D000465:Algorithms; D057205:Automation, Laboratory; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D040901:Proteomics / Q000379:methods*
chemical_list: D011506:Proteins