title: Life history: mother-specific proteins that promote aging.
abstract: A yeast mother cell progressively ages with each cell division and yet produces daughter cells that are largely rejuvenated, suggesting that mothers accumulate aging factors. Two current studies address this issue by identifying mother-specific long-lived proteins and, in the case of Pma1, evidence that asymmetric distribution drives mother cell aging.
authors.affiliation: Stowers Institute for Medical Research, Kansas City, MO 64110, USA; University of Kansas Medical Center, Kansas City, KS 66160, USA.
authors.forename: Chuankai
authors.initials: C
authors.lastname: Zhou
authors.affiliation: Stowers Institute for Medical Research, Kansas City, MO 64110, USA; University of Kansas Medical Center, Kansas City, KS 66160, USA.
authors.forename: Rong
authors.initials: R
authors.lastname: Li
authors.affiliation: Buck Institute for Research on Aging, Novato, CA 94945, USA. Electronic address: bkennedy@buckinstitute.org.
authors.forename: Brian K
authors.initials: BK
authors.lastname: Kennedy