title: A chiral stationary phase coated by surface molecularly imprinted polymer for separating 1,1'-binaphthalene-2,2'-diamine enantiomer by high performance liquid chromatography.
abstract: This report describes novel pathway for the development of a new type of CSP. A chiral stationary phase (CSP) prepared by coating a molecularly imprinted polymer (MIP) on the surface of silica gel (SMIP-CSP) showed a high separation factor (3.39) in separating racemic 1,1'-binaphthalene-2,2'-diamine (DABN) by high performance liquid chromatography (HPLC). Being the crosslinking agent, ethylene glycol dimethacrylate (EGDMA) was copolymerized with the monomer, methacrylic acid (MAA), in the presence of (R)-DABN as the template molecules on the surface of the silica gel particles to produce the SMIP-CSPs. The effects of the pretreatment temperature, the (R)-DABN content and the type of silica gel and monomer in the SMIP-CSPs on the separation of the racemic DABN were systematically investigated.
authors.affiliation: Polymer Materials Research Center, Key Laboratory of Superlight Materials & Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China. Electronic address: dhongxing@hrbeu.edu.cn.
authors.forename: Hongxing
authors.initials: H
authors.lastname: Dong
authors.affiliation: Polymer Materials Research Center, Key Laboratory of Superlight Materials & Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.
authors.forename: Meixia
authors.initials: M
authors.lastname: Zheng
authors.affiliation: Polymer Materials Research Center, Key Laboratory of Superlight Materials & Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.
authors.forename: Yiling
authors.initials: Y
authors.lastname: Ou
authors.affiliation: Polymer Materials Research Center, Key Laboratory of Superlight Materials & Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.
authors.forename: Chunhong
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Polymer Materials Research Center, Key Laboratory of Superlight Materials & Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China. Electronic address: liulijia@hrbeu.edu.cn.
authors.forename: Lijia
authors.initials: L
authors.lastname: Liu
authors.affiliation: Polymer Materials Research Center, Key Laboratory of Superlight Materials & Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.
authors.forename: Junqing
authors.initials: J
authors.lastname: Li
authors.affiliation: Polymer Materials Research Center, Key Laboratory of Superlight Materials & Surface Technology, Ministry of Education, College of Material Science and Chemical Engineering, Harbin Engineering University, Harbin 150001, China.
authors.forename: Xiaoguang
authors.initials: X
authors.lastname: Yang
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003432:Cross-Linking Reagents / Q000737:chemistry; D008689:Methacrylates / Q000737:chemistry; D054802:Molecular Imprinting; D009281:Naphthalenes / Q000737:chemistry / Q000302:isolation & purification*; D011109:Polymethacrylic Acids / Q000737:chemistry*; D012822:Silicon Dioxide; D013237:Stereoisomerism; D013696:Temperature
chemical_list: C431663:2,2'-diamino-1,1'-binaphthalene; D003432:Cross-Linking Reagents; D008689:Methacrylates; D009281:Naphthalenes; D011109:Polymethacrylic Acids; C030613:polymethacrylic acid; D012822:Silicon Dioxide; C004919:ethylene dimethacrylate
keywords: 1,1′-Binaphthalene-2,2′-diamine; Chiral separation; Coating; Surface molecularly imprinted polymers