title: A structured annotation frame for the transposable phages: a new proposed family "Saltoviridae" within the Caudovirales.
abstract: Enterobacteriophage Mu is the best studied and paradigm member of the transposable phages. Mu-encoded proteins have been annotated in detail in UniProtKB and linked to a controlled vocabulary describing the various steps involved in the phage lytic and lysogenic cycles. Transposable phages are ubiquitous temperate bacterial viruses with a dsDNA linear genome. Twenty-six of them, that infect α, β and γ-proteobacteria, have been sequenced. Their conserved properties are described. Based on these characteristics, we propose a reorganization of the Caudovirales, to allow for the inclusion of a "Saltoviridae" family and two newly proposed subfamilies, the "Myosaltovirinae" and "Siphosaltovirinae". The latter could temporarily be included in the existing Myoviridae and Siphoviridae families.
authors.affiliation: Swiss-Prot Group, Swiss Institute of Bioinformatics, Centre Médical Universitaire, CH-1211 Geneva 4, Switzerland.
authors.forename: Chantal
authors.initials: C
authors.lastname: Hulo
authors.affiliation: Swiss-Prot Group, Swiss Institute of Bioinformatics, Centre Médical Universitaire, CH-1211 Geneva 4, Switzerland.
authors.forename: Patrick
authors.initials: P
authors.lastname: Masson
authors.affiliation: Swiss-Prot Group, Swiss Institute of Bioinformatics, Centre Médical Universitaire, CH-1211 Geneva 4, Switzerland.
authors.forename: Philippe
authors.initials: P
authors.lastname: Le Mercier
authors.affiliation: Université Libre de Bruxelles, Génétique et Physiologie Bactérienne (LGPB), 12 rue des Professeurs Jeener et Brachet, 6041 Charleroi (Gosselies), Belgium. Electronic address: Ariane.Toussaint@ulb.ac.be.
authors.forename: Ariane
authors.initials: A
authors.lastname: Toussaint
mesh_terms: D017899:Caudovirales / Q000145:classification* / Q000235:genetics; D004251:DNA Transposable Elements; D058977:Molecular Sequence Annotation; D020560:Proteobacteria / Q000821:virology*; D014764:Viral Proteins / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements; D014764:Viral Proteins
keywords: Caudovirales; Phage protein annotation; Phage taxonomy; “Myosaltovirinae”; “Saltoviridae”; “Siphosaltovirinae”