title: Cerebral venous thrombosis in two patients with spontaneous intracranial hypotension.
abstract: Although few patients with spontaneous intracranial hypotension develop cerebral venous thrombosis, the association between these two entities seems too common to be simply a coincidental finding. We describe two cases of spontaneous intracranial hypotension associated with cerebral venous thrombosis. In one case, extensive cerebral venous thrombosis involved the superior sagittal sinus and multiple cortical cerebral veins. In the other case, only a right frontoparietal cortical vein was involved. Several mechanisms could contribute to the development of cerebral venous thrombosis in spontaneous intracranial hypotension. When spontaneous intracranial hypotension and cerebral venous thrombosis occur together, it raises difficult practical questions about the treatment of these two conditions. In most reported cases, spontaneous intracranial hypotension was treated conservatively and cerebral venous thrombosis was treated with anticoagulation. However, we advocate aggressive treatment of the underlying cerebrospinal fluid leak.
authors.affiliation: Department of Neurology, Hospital de Sabadell, Corporació Sanitària i Universitària Parc Taulí (CSIUPT), 08208 Sabadell, Spain.
authors.forename: M C
authors.initials: MC
authors.lastname: Garcia-Carreira
authors.affiliation: Department of Neurology, Hospital de Sabadell, Corporació Sanitària i Universitària Parc Taulí (CSIUPT), 08208 Sabadell, Spain.
authors.forename: D Cánovas
authors.initials: DC
authors.lastname: Vergé
authors.affiliation: Department of Radiology, Hospital de Sabadell, Corporació Sanitària i Universitària Parc Taulí (CSIUPT), 08208 Sabadell, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Branera
authors.affiliation: Department of Radiology, Hospital de Sabadell, Corporació Sanitària i Universitària Parc Taulí (CSIUPT), 08208 Sabadell, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Zauner
authors.affiliation: Department of Neurology, Hospital de Sabadell, Corporació Sanitària i Universitària Parc Taulí (CSIUPT), 08208 Sabadell, Spain.
authors.forename: J Estela
authors.initials: JE
authors.lastname: Herrero
authors.affiliation: Department of Neurology, Hospital de Sabadell, Corporació Sanitària i Universitària Parc Taulí (CSIUPT), 08208 Sabadell, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Tió
authors.affiliation: Department of Neurology, Hospital de Sabadell, Corporació Sanitària i Universitària Parc Taulí (CSIUPT), 08208 Sabadell, Spain.
authors.forename: G Ribera
authors.initials: GR
authors.lastname: Perpinyà