title: [Discriminating concentrations for three insecticides used in public health in a Lutzomyia longipalpis experimental strain from Colombia].
abstract: BACKGROUND
  In Colombia, periurban populations of Lutzomyia longipalpis , vector of the causative agent of visceral leishmaniasis in the upper and middle valley of the Magdalena River, may be exposed to insecticide applications with different purposes. Thus, it is important to begin a susceptibility surveillance of this species to insecticides.
  
  
  OBJECTIVE
  To determine indicators of susceptibility to three insecticides habitually used in public health, such as malathion, deltamethrin and lambda-cyhalothrin in an experimental strain of L. longipalpis .
  
  
  METHODS
  We used the method proposed by the Centers for Disease Control and Prevention. Groups of 10 to 15 unfed females were exposed to different concentrations of the insecticides using 250 ml glass bottles as test chambers. Mortality was registered every five minutes for an hour. Diagnostic concentrations and lethal times for each insecticide were calculated.
  
  
  RESULTS
  In the evaluated L. longipalpis strain, the diagnostic concentrations and times were 75 µg/ml and 25 minutes for malathion, 10 µg/ml and 35 minutes for deltamethrin, and 15 µg/ml during 30 minutes for lambda-cyhalothrin.
  
  
  CONCLUSIONS
  Baseline data over mortality response to three insecticides were established in a susceptibility strain of L. longipalpis vector. These indicators will allow establishing comparisons with populations of L. longipalpis exposed regularly or sporadically to chemical control measures to detect changes in their resistance to these insecticides.
authors.affiliation: Grupo de Entomología, Instituto Nacional de Salud, Bogotá, D.C, Colombia.
authors.forename: Catalina
authors.initials: C
authors.lastname: Marceló
authors.affiliation: Grupo de Entomología, Instituto Nacional de Salud, Bogotá, D.C, Colombia.
authors.forename: Olga Lucía
authors.initials: OL
authors.lastname: Cabrera
authors.affiliation: Grupo de Entomología, Instituto Nacional de Salud, Bogotá, D.C, Colombia.
authors.forename: Erika
authors.initials: E
authors.lastname: Santamaría
mesh_terms: D000818:Animals; D003105:Colombia; D004305:Dose-Response Relationship, Drug; D005260:Female; D007303:Insect Vectors / Q000187:drug effects*; D007305:Insecticide Resistance; D007306:Insecticides / Q000008:administration & dosage*; D007891:Leishmania; D008294:Malathion / Q000008:administration & dosage*; D009570:Nitriles / Q000008:administration & dosage*; D011576:Psychodidae / Q000145:classification; D011722:Pyrethrins / Q000008:administration & dosage*; D013045:Species Specificity; D013997:Time Factors
chemical_list: D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C017180:decamethrin; D008294:Malathion; C037304:cyhalothrin