title: [Medullary carcinoma experience in breast oncology unit of Hospital Juarez Mexico].
abstract: BACKGROUND
  Medullary breast cancer is a rare type, considered of good prognosis.
  
  
  OBJECTIVE
  To know the epidemiological and clinical characteristics of the population attended in the Hospital Juarez de Mexico, to know if they are alike to described worldwide and if the treatments proposed internationally are applicable for this hospitable center.
  
  
  METHODS
  We performed a retrospective analysis. Reviewing the records with histopathologic diagnosis of medullary breast cancer from February 1993 to February 2011. Finding 41 patients in the oncology unit of the institution.
  
  
  RESULTS
  We report an incidence of 3.04%, originating in 11 Mexican States, with a low to middle socioeconomic level in 39.02%. The average age at the time of diagnosis was 50 years. No family history was reported but some patients had medical history for type 2 diabetes, hypertension and previous breast cancer. 63.41% were menopausal. The average clinical size of the tumor was 58 mm. The 63% of the cases were located in the left breast. The 53.1% were clinical stages I and II, 46.3% were clinical stages III and in 9.6% of the cases primary tumor could not be assessed. Only 47% of the patients had positive axillary lynph nodes at diagnosis. The inmunohistochemestry was only reported in 14 of the 41 patients, according to the molecular classification of breast cancer: 8 were triple negative, 2 luminal A, 1 luminal B and 3 Her2neu.
  
  
  CONCLUSIONS
  The Mexican population presents epidemiological and clinical characteristics similar to those patients described in other studies worldwide.
authors.affiliation: Servicio de Oncología Adultos, Hospital Juárez de México, Mexico DF, Mexico. analyherrera@yahoo.com.
authors.forename: Xicoténcatl
authors.initials: X
authors.lastname: Jiménez-Villanueva
authors.affiliation: Servicio de Oncología Adultos, Hospital Juárez de México, Mexico DF, Mexico.
authors.forename: Angela
authors.initials: A
authors.lastname: Hernández-Rubio
authors.affiliation: Servicio de Oncología Adultos, Hospital Juárez de México, Mexico DF, Mexico.
authors.forename: Francisco Mario
authors.initials: FM
authors.lastname: García-Rodríguez
authors.affiliation: Servicio de Oncología Adultos, Hospital Juárez de México, Mexico DF, Mexico.
authors.forename: Rebeca Gil
authors.initials: RG
authors.lastname: García
authors.affiliation: Servicio de Oncología Adultos, Hospital Juárez de México, Mexico DF, Mexico.
authors.forename: Mario
authors.initials: M
authors.lastname: Moreno-Eutimio
authors.affiliation: Servicio de Oncología Adultos, Hospital Juárez de México, Mexico DF, Mexico.
authors.forename: Analy
authors.initials: A
authors.lastname: Herrera-Torre
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor; D001943:Breast Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D018276:Carcinoma, Medullary / Q000737:chemistry / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D015994:Incidence; D008593:Menopause; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000453:epidemiology / Q000473:pathology; D011379:Prognosis; D012189:Retrospective Studies; D012959:Socioeconomic Factors; D015996:Survival Rate; D064726:Triple Negative Breast Neoplasms / Q000737:chemistry / Q000453:epidemiology / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor
keywords: breast cancer; carcinoma; cáncer de mama; incidence; incidencia; medular; medullary