title: VectorBase: an updated bioinformatics resource for invertebrate vectors and other organisms related with human diseases.
abstract: VectorBase is a National Institute of Allergy and Infectious Diseases supported Bioinformatics Resource Center (BRC) for invertebrate vectors of human pathogens. Now in its 11th year, VectorBase currently hosts the genomes of 35 organisms including a number of non-vectors for comparative analysis. Hosted data range from genome assemblies with annotated gene features, transcript and protein expression data to population genetics including variation and insecticide-resistance phenotypes. Here we describe improvements to our resource and the set of tools available for interrogating and accessing BRC data including the integration of Web Apollo to facilitate community annotation and providing Galaxy to support user-based workflows. VectorBase also actively supports our community through hands-on workshops and online tutorials. All information and data are freely available from our website at https://www.vectorbase.org/.
authors.affiliation: Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.
authors.forename: Gloria I
authors.initials: GI
authors.lastname: Giraldo-Calderón
authors.affiliation: Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, IN 46556, USA ECK Institute for Global Health, University of Notre Dame, Notre Dame, IN 46556, USA semrich@nd.edu.
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Emrich
authors.affiliation: Department of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
authors.forename: Robert M
authors.initials: RM
authors.lastname: MacCallum
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
authors.forename: Gareth
authors.initials: G
authors.lastname: Maslen
authors.affiliation: Institute of Molecular Biology and Biotechnology (IMBB), FORTH, Vassilika Vouton,Nikolaou Plastira 100, 70013 Heraklion, Crete, Greece.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Dialynas
authors.affiliation: Institute of Molecular Biology and Biotechnology (IMBB), FORTH, Vassilika Vouton,Nikolaou Plastira 100, 70013 Heraklion, Crete, Greece.
authors.forename: Pantelis
authors.initials: P
authors.lastname: Topalis
authors.affiliation: Department of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
authors.forename: Nicholas
authors.initials: N
authors.lastname: Ho
authors.affiliation: Center for Research Computing, University of Notre Dame, Notre Dame, IN 46556, USA.
authors.forename: Sandra
authors.initials: S
authors.lastname: Gesing
authors.affiliation: Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, IN 46556, USA ECK Institute for Global Health, University of Notre Dame, Notre Dame, IN 46556, USA.
authors.forename: Gregory
authors.initials: G
authors.lastname: Madey
authors.affiliation: Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA ECK Institute for Global Health, University of Notre Dame, Notre Dame, IN 46556, USA.
authors.forename: Frank H
authors.initials: FH
authors.lastname: Collins
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK lawson@ebi.ac.uk.
authors.forename: Daniel
authors.initials: D
authors.lastname: Lawson
mesh_terms: D000818:Animals; D064229:Biological Ontologies; D030541:Databases, Genetic; D004199:Disease Vectors; D020869:Gene Expression Profiling; D014644:Genetic Variation; D016678:Genome; D023281:Genomics; D006801:Humans; D007305:Insecticide Resistance; D020407:Internet; D007448:Invertebrates / Q000235:genetics; D053858:Metabolic Networks and Pathways / Q000235:genetics