title: Single-layer transition metal dichalcogenide nanosheet-based nanosensors for rapid, sensitive, and multiplexed detection of DNA.
abstract: Single-layer transition metal dichalcogenide nanosheets, including MoS2, TiS2, and TaS2, are used as novel sensing platforms for sensitive and selective detection of DNA, based on their high fluorescence-quenching ability and different affinities toward single-stranded DNA and double-stranded DNA. Importantly, for the first time, a single-layer TaS2 nanosheet-based multiplexed DNA sensor is also developed.
authors.affiliation: Key Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials, National Jiangsu Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts and Telecommunications, 9 Wenyuan Road, Nanjing, 210023, China; School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798, Singapore.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.forename: Bing
authors.initials: B
authors.lastname: Zheng
authors.forename: Changfeng
authors.initials: C
authors.lastname: Zhu
authors.forename: Xiao
authors.initials: X
authors.lastname: Zhang
authors.forename: Chaoliang
authors.initials: C
authors.lastname: Tan
authors.forename: Hai
authors.initials: H
authors.lastname: Li
authors.forename: Bo
authors.initials: B
authors.lastname: Chen
authors.forename: Jian
authors.initials: J
authors.lastname: Yang
authors.forename: Junze
authors.initials: J
authors.lastname: Chen
authors.forename: Ying
authors.initials: Y
authors.lastname: Huang
authors.forename: Lianhui
authors.initials: L
authors.lastname: Wang
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D018011:Chalcogens / Q000737:chemistry*; D004247:DNA / Q000032:analysis* / Q000737:chemistry; D015342:DNA Probes / Q000737:chemistry; D057230:Limit of Detection; D008958:Models, Molecular; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D009690:Nucleic Acid Conformation; D013050:Spectrometry, Fluorescence; D013997:Time Factors; D028561:Transition Elements / Q000737:chemistry*
chemical_list: D018011:Chalcogens; D015342:DNA Probes; D028561:Transition Elements; D004247:DNA
keywords: DNA; fluorescence; multiplexed detection; nanosheets; transition metal dichalcogenides