title: [Combined hamartoma of the retina and retinal pigment epithelium. Anti-VEGF treatment of the associated choroidal neovascular membranes].
abstract: METHODS
  A 58 year-old female was diagnosed with a juxtapapillary combined hamartoma of the retina and retinal pigment epithelium (CHR-RPE) in her left eye 14 years ago. Her visual acuity in that eye was 20/20. Recently, she came to our department with a sudden visual loss and metamorphopsis in her left eye. After performing funduscopy, angiography and OCT, she was diagnosed with choroidal neovascular membrane (CNVM) at lesion border, and started on antiangiogenic therapy.
  
  
  CONCLUSIONS
  CHR-RPE, despite being a benign condition, may become complicated with severe visual impairment. Antiangiogenic therapy provides a good alternative to photodynamic therapy or laser photocoagulation for treatment of CNVM, avoiding adding iatrogenesis from these treatment to the complications associated with this pathology.
authors.affiliation: FEA de UGC Oftalmología, Hospital Comarcal de la Axarquía, Málaga, España. Electronic address: luciaechevarria98@gmail.com.
authors.forename: L
authors.initials: L
authors.lastname: Echevarría
authors.affiliation: FEA de UGC Oftalmología, Hospital Comarcal de la Axarquía, Málaga, España.
authors.forename: O
authors.initials: O
authors.lastname: Villena
authors.affiliation: FEA de UGC Oftalmología, Hospital Comarcal de la Axarquía, Málaga, España.
authors.forename: T
authors.initials: T
authors.lastname: Nievas
authors.affiliation: FEA de UGC Oftalmología, Hospital Comarcal de la Axarquía, Málaga, España.
authors.forename: R
authors.initials: R
authors.lastname: Bellido
mesh_terms: D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D005260:Female; D006222:Hamartoma / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D000069579:Ranibizumab / Q000627:therapeutic use*; D012164:Retinal Diseases / Q000188:drug therapy*; D015861:Retinal Neovascularization; D055213:Retinal Pigment Epithelium; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors*
chemical_list: D020533:Angiogenesis Inhibitors; D042461:Vascular Endothelial Growth Factor A; D000069579:Ranibizumab
keywords: Anti-VEGF; Choroidal neovascularization; Hamartoma; Iatrogenia; Iatrogenic; Membranas; Membranes; Neovascularización coroidea