title: [Lymphogranuloma venereum: the first Hungarian cases].
abstract: Lymphogranuloma venereum is a sexually transmitted infection caused by the Chlamydia trachomatis serovars L1-3. It has been found to be endemic in tropical countries. In the last decades several cases have been reported in Western Europe, particularly in men who have sex with men population infected with human immunodeficiency virus. The authors present three cases of lymphogranuloma venereum infections, observed at their department in 2013 and 2014. The three human immunodeficiency virus infected patients who belonged to men who have sex with men population had casual sexual contacts in Western Europe. The symptoms included urethral discharge, discomfort and inguinal lymphadenomegaly in two patients, and rectal pain, discharge and perianal ulceration in one patient. The diagnosis was confirmed by nucleic acid amplification test performed in samples obtained from urethral discharge and exudate of perianal ulcer; lymphogranuloma venereum 2b serovars were demonstrated in two patients and serovar 2 in one patient. Doxycyclin (daily dose of two times 100 mg for 21 days) resolved the symptoms in all cases. The authors conclude that lymphogranuloma venereum is a diagnostic challenge in Hungary, too. It is important to be aware of the altered clinical features of this disease to prevent complications and spreading.
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
authors.forename: András
authors.initials: A
authors.lastname: Bánvölgyi
authors.affiliation: Országos Epidemiológiai Központ II. Bakteriológiai Osztály, STI Laboratórium Budapest.
authors.forename: Eszter
authors.initials: E
authors.lastname: Balla
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
authors.forename: Péter
authors.initials: P
authors.lastname: Bognár
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
authors.forename: Béla
authors.initials: B
authors.lastname: Tóth
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
authors.forename: Eszter
authors.initials: E
authors.lastname: Ostorházi
authors.affiliation: Egyesített Szent László és Szent István Kórház V. Infektológiai Osztály Budapest.
authors.forename: Dénes
authors.initials: D
authors.lastname: Bánhegyi
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
authors.forename: Sarolta
authors.initials: S
authors.lastname: Kárpáti
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
authors.forename: Márta
authors.initials: M
authors.lastname: Marschalkó
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification*; D003937:Diagnosis, Differential; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D018451:Homosexuality, Male; D006801:Humans; D006814:Hungary; D008219:Lymphogranuloma Venereum / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D012307:Risk Factors; D065288:Serogroup; D012698:Serologic Tests; D012747:Sexual Partners; D012749:Sexually Transmitted Diseases / Q000175:diagnosis; D014195:Travel
chemical_list: D019380:Anti-HIV Agents
keywords: Chlamydia trachomatis; HIV; MSM; lymphogranuloma venereum