title: Breast cancer in 2014: A call back to reality!
abstract: In 2014, no major breakthroughs were made in understanding the biology of breast cancer or its management; few novel practice-changing studies were presented or published. Nevertheless, important negative results from studies that challenge some of the current concepts, particularly in drug development, underline 2014 as a year of ‘failed surrogates and precocious expectations’.
authors.affiliation: Breast Unit, Champalimaud Clinical Centre, Avenida De Brasília s/n, 1400-038 Lisbon, Portugal.
authors.forename: Fatima
authors.initials: F
authors.lastname: Cardoso
authors.affiliation: Department of Oncology and Radiotherapy, Medical University of Gdańsk, Dębinki 7, 80-211 Gdańsk, Poland.
authors.forename: Elżbieta
authors.initials: E
authors.lastname: Senkus
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D017024:Chemotherapy, Adjuvant / Q000379:methods; D055808:Drug Discovery / Q000639:trends; D005260:Female; D006801:Humans; D058990:Molecular Targeted Therapy / Q000639:trends; D020360:Neoadjuvant Therapy / Q000379:methods; D017410:Practice Guidelines as Topic
chemical_list: D000970:Antineoplastic Agents