title: Choroidal thickness in macular holes: a case-control study.
abstract: OBJECTIVE
  To evaluate choroidal thickness of patients with unilateral full-thickness macular holes (FTMHs) and contralateral vitreomacular adhesion (VMA) and healthy eyes.
  
  
  METHODS
  A retrospective case-control study of patients with unilateral FTMH and contralateral VMA and matched healthy controls was performed. Choroidal thickness was measured at five locations (subfoveal and 1 mm and 2 mm from the center of the fovea nasally and temporally) and compared between groups.
  
  
  RESULTS
  Nineteen case patients and 19 control patients were analyzed. Eyes with FTMH had thinner choroids compared with the contralateral eyes with VMA and the control eyes at all locations except 2 mm temporal from the fovea. Eyes with VMA had thinner choroids nasally from the fovea compared with control eyes.
  
  
  CONCLUSIONS
  Choroidal thickness was significantly decreased in eyes with FTMH except at 2 mm temporal to the fovea and decreased in contralateral eyes with VMA in the nasal directions, suggesting an association between choroidal thinning and macular hole.
authors.forename: Lucy T
authors.initials: LT
authors.lastname: Xu
authors.forename: Sunil K
authors.initials: SK
authors.lastname: Srivastava
authors.forename: Justis P
authors.initials: JP
authors.lastname: Ehlers
authors.forename: Peter K
authors.initials: PK
authors.lastname: Kaiser
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D002829:Choroid / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D009929:Organ Size; D012167:Retinal Perforations / Q000150:complications* / Q000175:diagnosis; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity