title: [Effects of ß-alanine supplementation on athletic performance].
abstract: Carnosine, dipeptide formed by amino acids ß-alanine and L-histidine, has important physiological functions among which its antioxidant and related memory and learning. However, in connection with the exercise, the most important functions would be associated with muscle contractility, improving calcium sensitivity in muscle fibers, and the regulatory function of pH. Thus, it is proposed that carnosine is the major intracellular buffer, but could contribute to 7-10% in buffer or buffer capacity. Since carnosine synthesis seems to be limited by the availability of ß-alanine supplementation with this compound has been gaining increasing popularity among the athlete population. Therefore, the objective of this study literature review was to examine all those research works have shown the effect of ß-alanine supplementation on athletic performance. Moreover, it also has attempted to establish a specific dosage that maximizing the potential benefits, minimize paresthesia, the main side effect presented in response to supplementation.
authors.affiliation: Departamento de Ciencias de la Actividad Física y el Deporte, Universidad Alfonso X El Sabio. Villanueva de la Cañada, Madrid.. rdomiher@uax.es.
authors.forename: Raúl
authors.initials: R
authors.lastname: Domínguez
authors.affiliation: Departamento de Ciencias de la Actividad Física y el Deporte, Universidad Alfonso X El Sabio. Villanueva de la Cañada, Madrid.. jhernlou@myuax.com.
authors.forename: Juan
authors.initials: J
authors.lastname: Hernández Lougedo
authors.affiliation: Departamento de Ciencias de la Actividad Física y el Deporte, Universidad Alfonso X El Sabio. Villanueva de la Cañada, Madrid.. jmatmuo@uax.es.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Maté-Muñoz
authors.affiliation: Departamento de Fisiología e Inmunología. Universidad de Barcelona, Barcelona. España.. mavigarcas@gmail.com.
authors.forename: Manuel Vicente
authors.initials: MV
authors.lastname: Garnacho-Castaño
mesh_terms: D054874:Athletic Performance; D002336:Carnosine / Q000494:pharmacology; D019587:Dietary Supplements; D006801:Humans; D009119:Muscle Contraction / Q000187:drug effects; D018482:Muscle, Skeletal / Q000187:drug effects / Q000502:physiology; D010292:Paresthesia / Q000139:chemically induced; D015091:beta-Alanine / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*
chemical_list: D015091:beta-Alanine; D002336:Carnosine