title: The effectiveness of exercise interventions for improving health-related quality of life from diagnosis through active cancer treatment.
abstract: OBJECTIVE
  To evaluate the effectiveness of exercise interventions on overall health-related quality of life (HRQOL) and its domains among adults scheduled to, or actively undergoing, cancer treatment.
  
  
  METHODS
  11 electronic databases were searched through November 2011. In addition, the authors searched PubMed's related article feature, trial registries, and reference lists of included trials and related reviews.
  
  
  RESULTS
  56 trials with 4,826 participants met the inclusion criteria. At 12 weeks, people exposed to exercise interventions had greater improvement in overall HRQOL, physical functioning, role functioning, social functioning, and fatigue. Improvement in HRQOL was associated with moderate-to-vigorous intensity exercise interventions.
  
  
  CONCLUSIONS
  Exercise can be a useful tool for managing HRQOL and HRQOL domains for people scheduled to, or actively undergoing, cancer treatment. More methodologically rigorous trials are needed to examine the attributes of exercise programs most effective for improving HRQOL.
  
  
  CONCLUSIONS
  Evidence from this review supports the incorporation of exercise programs of moderate-to-vigorous intensity for the management of HRQOL among people scheduled to, or actively undergoing, cancer treatment into clinical guidelines through the Oncology Nursing Society's Putting Evidence Into Practice resources.
authors.affiliation: Department of Pediatrics and Family and Community Medicine, University of New Mexico (UNM) Cancer Center in Albuquerque.
authors.forename: Shiraz I
authors.initials: SI
authors.lastname: Mishra
authors.affiliation: Department of Epidemiology, The Johns Hopkins Center for Clinical Trials.
authors.forename: Roberta W
authors.initials: RW
authors.lastname: Scherer
authors.affiliation: Division of General Internal Medicine, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
authors.forename: Claire
authors.initials: C
authors.lastname: Snyder
authors.affiliation: Department of Neurology, University of Maryland Rehabilitation and Orthopaedic Institute in Baltimore.
authors.forename: Paula
authors.initials: P
authors.lastname: Geigle
authors.affiliation: School of Population and Public Health, University of British Colombia, Vancouver, Canada.
authors.forename: Carolyn
authors.initials: C
authors.lastname: Gotay
mesh_terms: D005081:Exercise Therapy; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis / Q000534:rehabilitation* / Q000628:therapy; D011788:Quality of Life; D013997:Time Factors; D016896:Treatment Outcome
keywords: anxiety; depression; exercise; fatigue; health status; physical activity; quality of life; resistance training; survivors; yoga