title: [68Ga-DOTA-PET for neuroendocrine tumours].
abstract: Neuroendocrine tumors (NET) are found in several organs and called NET tumors. They are relatively rare, most of them giving no symptoms and remaining undetected. Most NETs arise from the gut, stomach and bronchus. These tumors are diagnosed either by histology or by imaging. A typical feature of NETs is abundance of somatostatin receptors on the cell surface, which makes it possible to image the tumor by nuclear methods as well as estimate the response to treatment by somatostatin analogues ("theranostics"). In order to improve the diagnosis of NETs we started to produce 68Ga-DOTA peptides for PET.
authors.affiliation: HYKS, HUS-Kuvantaminen.
authors.forename: Antti
authors.initials: A
authors.lastname: Loimaala
authors.forename: Hanna
authors.initials: H
authors.lastname: Mäenpää
authors.forename: Tiina
authors.initials: T
authors.lastname: Lipponen
authors.forename: Jukka
authors.initials: J
authors.lastname: Schildt
authors.forename: Eeva-Liisa
authors.initials: EL
authors.lastname: Kämäräinen
authors.forename: Lauri
authors.initials: L
authors.lastname: Karhumäki
authors.forename: Aapo
authors.initials: A
authors.lastname: Ahonen
mesh_terms: D006801:Humans; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging*; D015282:Octreotide / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D009942:Organometallic Compounds / Q000138:chemical synthesis; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals / Q000138:chemical synthesis
chemical_list: C550726:68Ga-octreotide, DOTA(0)-Tyr(3)-; D009942:Organometallic Compounds; D019275:Radiopharmaceuticals; D015282:Octreotide