title: [Immediate and long-term results of brachytherapy in complex treatment for esophageal cancer].
abstract: For treatment of cancer of the thoracic esophagus, the method of neoadjuvant chemoradiotherapy (CRT) with a use of intraluminal brachytherapy (BT) was performed. The study included 51 patients (mean age 56.9 ± 4.3 years). The length of the primary tumor up to 6 cm was determined in 18 patients, more than 6 cm--33 patients. CRT included three BT sessions (7Gy X 3; q7d) and two cycles of chemotherapy (PF; q28d). After CRT in 30 (62.4%) patients there was marked a complete or partial radiological tumor regression. In 40-45 days after CRT surgery performed. Subtotal resection of esophagus of the Lewis type was performed in 29 cases, transtracheal ex- tirpation of the esophagus--in 2, minimally invasive esopha- gectomy--in 17 cases. Postoperative complications occurred in 22 (44%) patients; one patient died (2%). In 11 (23%) patients morphological investigation revealed a complete regression of the primary tumor. Thus, a use of intraluminal BT in combination with chemotherapy in many cases promoted reducing the size of the primary tumor of the esophagus, which was an effective factor in improving surgical results.
authors.forename: S Iu
authors.initials: SIu
authors.lastname: Dvoretskiĭ
authors.forename: A M
authors.initials: AM
authors.lastname: Shcherbakov
authors.forename: S V
authors.initials: SV
authors.lastname: Kanaev
authors.forename: E I
authors.initials: EI
authors.lastname: Tiuriaeva
authors.forename: Z A-G
authors.initials: ZA
authors.lastname: Radzhadova
authors.forename: I V
authors.initials: IV
authors.lastname: Komarov
authors.forename: A A
authors.initials: AA
authors.lastname: Avanesian
authors.forename: A I
authors.initials: AI
authors.lastname: Semenova
authors.forename: N V
authors.initials: NV
authors.lastname: Khandogin
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Ivashikin
authors.forename: E V
authors.initials: EV
authors.lastname: Levchenko
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001918:Brachytherapy; D059186:Chemoradiotherapy, Adjuvant; D004938:Esophageal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000628:therapy; D016629:Esophagectomy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome