title: Pulsatile ocular blood flow changes after panretinal photocoagulation treatment in patients with proliferative diabetic retinopathy.
abstract: OBJECTIVE
  To prospectively assess the effects of panretinal photocoagulation (PRP) treatment on pulsatile ocular blood flow (POBF) in patients with proliferative diabetic retinopathy (PDRP).
  
  
  METHODS
  The study included 40 eyes with PDRP in 27 patients. The PRP treatments were completed in 3 sessions with 3-week intervals. The intraocular pressure (IOP), pulse amplitude (PA), pulse volume (PV), and POBF changes that arose during the sessions were recorded using a blood flow analyzer.
  
  
  RESULTS
  The average age of the patients was 57.37 ± 11.14 years. The pre-PRP basal IOP, PA, PV, and POBF values were 20.44 ± 4.13 mmHg, 4.23 ± 1.73 mmHg, 6.89 ± 2.28 μL, and 21.86 ± 5.83 μL/s, respectively. One month after the completion of the PRP sessions, the values were 18.49 ± 4.44 mmHg, 2.78 ± 1.13 mmHg, 5.27 ± 2.08 μL, and 15.89 ± 5.05 μL/s, respectively, and the differences were significant (P = 0.001, P < 0.0001, P < 0.0001, and P < 0.0001, respectively).
  
  
  CONCLUSIONS
  PRP treatment reduces the choroidal blood flow and consequently causes significant decreases in IOP, PA, PV, and POBE .
authors.affiliation: Department of Ophthalmology, Karadeniz Technical University, Trabzon, Turkey. doktorademturk@yahoo.com
authors.forename: Adem
authors.initials: A
authors.lastname: Türk
authors.forename: Cenap Mahmut
authors.initials: CM
authors.lastname: Esenülkü
authors.forename: Nurettin
authors.initials: N
authors.lastname: Akyol
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kola
authors.forename: Hidayet
authors.initials: H
authors.lastname: Erdöl
authors.forename: Halil İbrahim
authors.initials: Hİ
authors.lastname: İmamoğlu
mesh_terms: D000328:Adult; D000368:Aged; D003930:Diabetic Retinopathy / Q000503:physiopathology* / Q000628:therapy*; D005123:Eye / Q000098:blood supply* / Q000528:radiation effects*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000528:radiation effects; D008028:Light Coagulation; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011673:Pulsatile Flow / Q000528:radiation effects*; D012039:Regional Blood Flow / Q000528:radiation effects*