title: Clinical outcome analysis of 47 patients with advanced head and neck cancer with preoperative suspicion of carotid artery invasion.
abstract: The purpose of this study was to retrospectively analyze the feasibility of the surgical management of the carotid artery in advanced head and neck cancer with preoperative suspicion of carotid artery invasion.
  
  
  
  A total of 47 patients were retrospectively analyzed. Twenty-one patients (44.7%) received surgery as initial treatment, and 26 patients (55.3%) had salvage surgical treatment for recurrences. Intraoperative dissection and preservation of the carotid artery was achieved in 39 patients (83%). Eight patients underwent carotid resection with/without reconstruction (17%).
  
  
  
  The cumulative 2-year and 5-year overall survival rates were 40.4% and 34%, and the disease-specific survival rates were 59.5% and 55.3%, respectively. The overall perioperative mortality rate was 6.4%. Carotid blowout developed in 6 patients.
  
  
  
  Surgical treatment of the carotid artery in selected patients can provide locoregional control and the possibility of prolonged disease-free survival with acceptable morbidity. © 2015 Wiley Periodicals, Inc. Head Neck 38: E287-E292, 2016.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University, College of Medicine, Seoul, Korea.
authors.forename: Eun-Jae
authors.initials: EJ
authors.lastname: Chung
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Ilsong Memorial Institute of Head and Neck Cancer, Hallym University, College of Medicine, Seoul, Korea.
authors.forename: Kee-Hwan
authors.initials: KH
authors.lastname: Kwon
authors.affiliation: Department of Radiology, Hallym University, College of Medicine, Seoul, Korea.
authors.forename: Dae-Young
authors.initials: DY
authors.lastname: Yoon
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Hallym University, College of Medicine, Seoul, Korea.
authors.forename: Sung-Woo
authors.initials: SW
authors.lastname: Cho
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Hallym University, College of Medicine, Seoul, Korea.
authors.forename: Eung-Joong
authors.initials: EJ
authors.lastname: Kim
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, Ilsong Memorial Institute of Head and Neck Cancer, Hallym University, College of Medicine, Seoul, Korea.
authors.forename: Young-Soo
authors.initials: YS
authors.lastname: Rho
mesh_terms: D002339:Carotid Arteries / Q000473:pathology* / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D015996:Survival Rate
keywords: carotid artery; head and neck cancer; postoperative complication; prognosis; surgery