title: EURADOS intercomparison on emergency radiobioassay.
abstract: Nine laboratories participated in an intercomparison exercise organised by the European Radiation Dosimetry Group (EURADOS) for emergency radiobioassay involving four high-risk radionuclides ((239)Pu, (241)Am, (90)Sr and (226)Ra). Diverse methods of analysis were used by the participating laboratories for the in vitro determination of each of the four radionuclides in urine samples. Almost all the methods used are sensitive enough to meet the requirements for emergency radiobioassay derived for this project in reference to the Clinical Decision Guide introduced by the NCRP. Results from most of the methods meet the requirements of ISO 28218 on accuracy in terms of relative bias and relative precision. However, some technical gaps have been identified. For example, some laboratories do not have the ability to assay samples containing (226)Ra, and sample turnaround time would be expected to be much shorter than that reported by many laboratories, as timely results for internal contamination and early decisions on medical intervention are highly desired. Participating laboratories are expected to learn from each other on the methods used to improve the interoperability among these laboratories.
authors.affiliation: Radiation Protection Bureau, Health Canada, Ottawa, Canada K1A 1C1 li.chunsheng@hc-sc.gc.ca.
authors.forename: Chunsheng
authors.initials: C
authors.lastname: Li
authors.affiliation: Institute of Radiation Protection, ENEA, Rome, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Battisti
authors.affiliation: French Alternative Energies and Atomic Energy Commission, Fontenay aux Roses, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Berard
authors.affiliation: Laboratoire de Contrôle Radiotoxicologique, Service de Protection Radiologique des Armées, Clamart, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Cazoulat
authors.affiliation: International Atomic Energy Agency, Vienna, Austria.
authors.forename: Antonio
authors.initials: A
authors.lastname: Cuellar
authors.affiliation: International Atomic Energy Agency, Vienna, Austria.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Cruz-Suarez
authors.affiliation: Chalk River Laboratory, Atomic Energy of Canada Limited, Chalk River, Canada K0J 1J0.
authors.forename: Xiongxin
authors.initials: X
authors.lastname: Dai
authors.affiliation: Institute of Radiation Protection, ENEA, Rome, Italy.
authors.forename: Isabella
authors.initials: I
authors.lastname: Giardina
authors.affiliation: Public Health England, Chilton OX11 0RQ, UK.
authors.forename: Derek
authors.initials: D
authors.lastname: Hammond
authors.affiliation: Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, Madrid 28040, Spain.
authors.forename: Carolina
authors.initials: C
authors.lastname: Hernandez
authors.affiliation: Radiation Protection Bureau, Health Canada, Ottawa, Canada K1A 1C1.
authors.forename: Stephen
authors.initials: S
authors.lastname: Kiser
authors.affiliation: Radiation Protection Bureau, Health Canada, Ottawa, Canada K1A 1C1.
authors.forename: Raymond
authors.initials: R
authors.lastname: Ko
authors.affiliation: Chalk River Laboratory, Atomic Energy of Canada Limited, Chalk River, Canada K0J 1J0.
authors.forename: Sheila
authors.initials: S
authors.lastname: Kramer-Tremblay
authors.affiliation: Laboratoire de Contrôle Radiotoxicologique, Service de Protection Radiologique des Armées, Clamart, France.
authors.forename: Yannick
authors.initials: Y
authors.lastname: Lecompte
authors.affiliation: GEOCISA, Madrid, Spain.
authors.forename: Eva
authors.initials: E
authors.lastname: Navarro
authors.affiliation: GEOCISA, Madrid, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: Navas
authors.affiliation: Radiation Protection Bureau, Health Canada, Ottawa, Canada K1A 1C1.
authors.forename: Baki
authors.initials: B
authors.lastname: Sadi
authors.affiliation: Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, Madrid 28040, Spain.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Sierra
authors.affiliation: Belgium Nuclear Research Center, SCK-CEN, Mol B-2400, Belgium.
authors.forename: Freddy
authors.initials: F
authors.lastname: Verrezen
authors.affiliation: Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, Madrid 28040, Spain.
authors.forename: Maria A
authors.initials: MA
authors.lastname: Lopez
mesh_terms: D001681:Biological Assay / Q000379:methods*; D004635:Emergency Medicine / Q000379:methods*; D006801:Humans; D007753:Laboratories / Q000592:standards*; D011834:Radiation Monitoring / Q000379:methods*; D011848:Radioactive Pollutants / Q000652:urine*; D011854:Radiochemistry / Q000379:methods*; D011874:Radiometry; D012015:Reference Standards; D013673:Technology Assessment, Biomedical; D016482:Urinalysis / Q000379:methods*; D014556:Urine / Q000737:chemistry
chemical_list: D011848:Radioactive Pollutants