title: Hemostatic abnormalities in critically ill patients.
abstract: Hemostatic abnormalities frequently occur in critically ill patients and may vary from prolonged global clotting tests or isolated thrombocytopenia, to composite defects, such as consumption coagulopathies. There are many reasons for a disturbed coagulation in intensive care patients, and each of these underlying syndromes may require specific therapeutic intervention. Hence, an adequate differential diagnosis and initiation of proper (supportive) therapeutic strategies are critical to decrease morbidity and mortality in critically ill patients with hemostatic abnormalities.
authors.affiliation: Department of Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, m.m.levi@amc.uva.nl.
authors.forename: Marcel
authors.initials: M
authors.lastname: Levi
authors.forename: Suthesh
authors.initials: S
authors.lastname: Sivapalaratnam
mesh_terms: D001778:Blood Coagulation Disorders / Q000150:complications*; D016638:Critical Illness; D003937:Diagnosis, Differential; D006801:Humans; D007249:Inflammation / Q000150:complications; D007362:Intensive Care Units; D011517:Prothrombin Time; D013921:Thrombocytopenia / Q000150:complications* / Q000175:diagnosis