title: Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4.
abstract: The pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4 strain has been synthesized using a combination of sequential glycosylations and [3 + 2] block synthetic strategy from the suitably protected monosaccharide intermediates. Thioglycosides and glycosyl trichloroacetimidate derivatives have been used as glycosyl donors in the glycosylations.
authors.affiliation: Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, BS-10/1, Sector 10, Jankipuram extension, Sitapur Road, Lucknow, 226 031, India.
authors.forename: Pintu Kumar
authors.initials: PK
authors.lastname: Mandal
keywords: Escherichia coli; O-antigen; glycosylation; lipopolysaccharide; pentasaccharide