title: Prostate-specific antigen and perfluoroalkyl acids in the C8 health study population.
abstract: OBJECTIVE
  To inform questions raised by inconsistent findings regarding an association between perfluoroalkyl acids (PFAAs) and prostate cancer by assessing the relationship of PFAAs in human serum to prostate-specific antigen (PSA).
  
  
  METHODS
  Using 2005 to 2006 survey data from a large survey population, we compared serum PFAA concentrations in adult males with PSA concentrations adjusted for risk factors including age, body mass index, smoking status, and socioeconomic status.
  
  
  RESULTS
  Perfluoroalkyl acids are not consistently associated with PSA concentration in general, or with PSA more than 4.0.
  
  
  CONCLUSIONS
  These findings do not provide evidence that PFAA exposure is associated with PSA.
authors.affiliation: From the Department of Occupational and Environmental Health (Dr Ducatman), School of Public Health, and Department of Medicine, School of Medicine, and Clinical Translational Science Institute; Cancer Center (Drs Ducatman and Fan); Department of Biostatistics (Mr Zhang), School of Public Health, West Virginia University, Morgantown; and Department of Epidemiology and Statistics (Dr Fan), School of Public Health, Hebei United University, Tangshan, China.
authors.forename: Alan
authors.initials: A
authors.lastname: Ducatman
authors.forename: Jianjun
authors.initials: J
authors.lastname: Zhang
authors.forename: Hongmin
authors.initials: H
authors.lastname: Fan
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D017738:Alkanesulfonic Acids / Q000097:blood; D002210:Caprylates / Q000097:blood; D005227:Fatty Acids; D005466:Fluorocarbons / Q000097:blood*; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D009820:Ohio; D017430:Prostate-Specific Antigen / Q000097:blood*; D012307:Risk Factors; D013451:Sulfonic Acids / Q000097:blood; D014903:West Virginia
chemical_list: D017738:Alkanesulfonic Acids; D002210:Caprylates; D005227:Fatty Acids; D005466:Fluorocarbons; D013451:Sulfonic Acids; C471071:perfluorohexanesulfonic acid; C101816:perfluoro-n-nonanoic acid; C023036:perfluorooctanoic acid; C076994:perfluorooctane sulfonic acid; D017430:Prostate-Specific Antigen