title: Age-related loss of lumbar spinal lordosis and mobility--a study of 323 asymptomatic volunteers.
abstract: BACKGROUND
  The understanding of the individual shape and mobility of the lumbar spine are key factors for the prevention and treatment of low back pain. The influence of age and sex on the total lumbar lordosis and the range of motion as well as on different lumbar sub-regions (lower, middle and upper lordosis) in asymptomatic subjects still merits discussion, since it is essential for patient-specific treatment and evidence-based distinction between painful degenerative pathologies and asymptomatic aging.
  
  
  RESULTS
  A novel non-invasive measuring system was used to assess the total and local lumbar shape and its mobility of 323 asymptomatic volunteers (age: 20-75 yrs; BMI <26.0 kg/m2; males/females: 139/184). The lumbar lordosis for standing and the range of motion for maximal upper body flexion (RoF) and extension (RoE) were determined. The total lordosis was significantly reduced by approximately 20%, the RoF by 12% and the RoE by 31% in the oldest (>50 yrs) compared to the youngest age cohort (20-29 yrs). Locally, these decreases mostly occurred in the middle part of the lordosis and less towards the lumbo-sacral and thoraco-lumbar transitions. The sex only affected the RoE.
  
  
  CONCLUSIONS
  During aging, the lower lumbar spine retains its lordosis and mobility, whereas the middle part flattens and becomes less mobile. These findings lay the ground for a better understanding of the incidence of level- and age-dependent spinal disorders, and may have important implications for the clinical long-term success of different surgical interventions.
authors.affiliation: Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Marcel
authors.initials: M
authors.lastname: Dreischarf
authors.affiliation: Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Laia
authors.initials: L
authors.lastname: Albiol
authors.affiliation: Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Antonius
authors.initials: A
authors.lastname: Rohlmann
authors.affiliation: Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Esther
authors.initials: E
authors.lastname: Pries
authors.affiliation: Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Maxim
authors.initials: M
authors.lastname: Bashkuev
authors.affiliation: Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Zander
authors.affiliation: Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Georg
authors.initials: G
authors.lastname: Duda
authors.affiliation: Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Claudia
authors.initials: C
authors.lastname: Druschel
authors.affiliation: Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Patrick
authors.initials: P
authors.lastname: Strube
authors.affiliation: Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Putzier
authors.affiliation: Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Schmidt
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D058070:Asymptomatic Diseases; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D008141:Lordosis / Q000175:diagnosis* / Q000473:pathology; D008161:Lumbosacral Region / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011187:Posture; D016059:Range of Motion, Articular; D018709:Statistics, Nonparametric; D055815:Young Adult