title: Therapeutic strategies in colonic cancer.
abstract: Colonic cancer is the most common malignancy of the digestive tract, representing 13% of all malignancies. The aim of the study is to evaluate the current therapeutic strategy in patients with CC. Mortality from the disease is declining in many Western countries; this may be the result of screening for CC, resection of adenomas, early detection of tumoral lesions and the use of individualized therapeutic strategies. The multimodal treatment of the disease includes different sequences such as: surgery, chemotherapy, radiotherapy,immunotherapy. Current advances in the research of mechanisms of carcinogenesis in CC make it possible to use genetic information in order to establish the prognostic and predictive factors for selecting the patients for individualized therapy. The current methods of CC evaluation allow the planning of individualized therapeutic strategies, which would lead to optimal results.
authors.forename: D
authors.initials: D
authors.lastname: Dinu
authors.forename: R
authors.initials: R
authors.lastname: Birla
authors.forename: A
authors.initials: A
authors.lastname: Caragui
authors.forename: S
authors.initials: S
authors.lastname: Constantinoiu
mesh_terms: D017024:Chemotherapy, Adjuvant; D003082:Colectomy / Q000379:methods; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000601:surgery* / Q000628:therapy; D055088:Early Detection of Cancer; D019317:Evidence-Based Medicine; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D009367:Neoplasm Staging; D011182:Postoperative Care; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome