title: Evolution of differentiated thyroid cancer: a decade of thyroidectomies in a single institution.
abstract: BACKGROUND
  Numerous studies have shown an increase in the incidence of thyroid cancer (TC) in recent years.
  
  
  OBJECTIVE
  In this paper, we reviewed the incidence of TC in a series of patients undergoing thyroid surgery at a single institution over a 10-year period.
  
  
  METHODS
  The cohorts were divided into two periods (2001-2005 and 2006-2010) with the purpose of comparing various clinicopathologic variables.
  
  
  RESULTS
  A total of 1,263 patients were included. A significant increase in the number of malignancies was shown in the second period, namely 90 cases in 2001-2005 (15.2% of all interventions) compared to 163 cases in 2006-2010 (24.3%) (p < 0.001). These differences were attributed to an increase in papillary thyroid carcinoma (PTC), as there were 66 PTC cases in the first period (11.13% of thyroidectomies performed) compared to 129 cases in the second period (19.25%). There were no clinicohistological differences among PTC cases in these two periods.
  
  
  CONCLUSIONS
  Over the last decade, there has been an increase in the incidence of TC in patients undergoing thyroid surgery. This increase is exclusively due to increases in PTC. Our study verifies the existence of this trend in our geographical area, similar to that noted in other parts of the world.
authors.affiliation: Department of Endocrinology, Universitat Autònoma de Barcelona, Spain ; Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain.
authors.forename: Carles
authors.initials: C
authors.lastname: Zafon
authors.affiliation: Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Universitat Autònoma de Barcelona, Spain.
authors.forename: Juan Antonio
authors.initials: JA
authors.lastname: Baena
authors.affiliation: Department of Pathology, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Spain.
authors.forename: Josep
authors.initials: J
authors.lastname: Castellví
authors.affiliation: Department of Endocrinology, Universitat Autònoma de Barcelona, Spain ; Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Obiols
authors.affiliation: Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Universitat Autònoma de Barcelona, Spain.
authors.forename: Oscar
authors.initials: O
authors.lastname: Gonzalez
authors.affiliation: Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Universitat Autònoma de Barcelona, Spain.
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Fort
authors.affiliation: Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Universitat Autònoma de Barcelona, Spain.
authors.forename: Ramon
authors.initials: R
authors.lastname: Vilallonga
authors.affiliation: Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Universitat Autònoma de Barcelona, Spain.
authors.forename: Enric
authors.initials: E
authors.lastname: Caubet
authors.affiliation: Endocrine, Bariatric and Metabolic Unit, Department of General Surgery, Universitat Autònoma de Barcelona, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Armengol
authors.affiliation: Department of Endocrinology, Universitat Autònoma de Barcelona, Spain ; Diabetes and Metabolism Research Unit, Vall Hebron Institut de Recerca (VHIR), Universitat Autònoma de Barcelona and CIBERDEM (ISCIII), Barcelona, Spain.
authors.forename: Jordi
authors.initials: J
authors.lastname: Mesa
keywords: Incidence; Thyroid cancer; Thyroidectomies