title: Quality of life in children with CF: Psychometrics and relations with stress and mealtime behaviors.
abstract: BACKGROUND
  The purpose of this study was to evaluate the utility of the Cystic Fibrosis Questionnaire-Revised (CFQ-R) with toddlers and preschool-aged children. Clinically relevant relations between health-related quality of life (HRQOL), stress, and mealtime behaviors have not been examined. It was hypothesized that problematic mealtime behaviors and increased stress would be negatively associated with HRQOL.
  
  
  METHODS
  Parents of 73 children (2-6 years) with CF completed questionnaires assessing their children's generic (PedsQL) and CF-specific HRQOL, parenting and CF-specific stress, and mealtime behaviors.
  
  
  RESULTS
  CFQ-R Physical, Eating, and Respiratory HRQOL subscales had acceptable to strong reliability (alphas = 0.73-0.86); other scales approached acceptable reliability. Lower CF-specific stress was associated with higher CFQ-R Eating HRQOL (B = -0.84; P < 0.05) scores. Fewer eating problems were associated with higher CFQ-R Eating (B = -1.17; P < 0.0001) and Weight HRQOL (B = -0.78; P < 0.01) scores.
  
  
  CONCLUSIONS
  As hypothesized, problematic eating and higher CF-specific stress was associated with lower CF-specific HRQOL. The CFQ-R has promise for use in young children with CF, but will need to be modified to exchange items not relevant to preschoolers with items that are more relevant to this age group.
authors.affiliation: Department of Behavioral Sciences & Social Medicine, Florida State University College of Medicine, Tallahassee, Florida.
authors.forename: Kimberly A
authors.initials: KA
authors.lastname: Driscoll
authors.affiliation: Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Avani C
authors.initials: AC
authors.lastname: Modi
authors.affiliation: Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Stephanie S
authors.initials: SS
authors.lastname: Filigno
authors.affiliation: Department of Psychology, Oklahoma State University, Stillwater, Oklahoma.
authors.forename: Erin E
authors.initials: EE
authors.lastname: Brannon
authors.affiliation: Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Leigh Ann
authors.initials: LA
authors.lastname: Chamberlin
authors.affiliation: Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Lori J
authors.initials: LJ
authors.lastname: Stark
authors.affiliation: Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Scott W
authors.initials: SW
authors.lastname: Powers
mesh_terms: D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications / Q000523:psychology*; D005247:Feeding Behavior / Q000523:psychology*; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D010290:Parents; D011594:Psychometrics; D011788:Quality of Life; D013315:Stress, Psychological / Q000150:complications / Q000523:psychology*; D011795:Surveys and Questionnaires
keywords: children; cystic fibrosis; health-related quality of life; mealtime behavior; parent stress