title: Dangerous triplet: Polycystic ovary syndrome, oral contraceptives and Kounis syndrome.
abstract: Polycystic ovary syndrome is characterized by ovulatory dysfunction, androgen excess and polycystic ovaries and is associated with hypertension, diabetes, metabolic syndrome and cardiovascular events. Oral contraceptives constitute ﬁrst-line treatment, particularly when symptomatic hyperandrogenism is present. However, these drugs are associated with cardiovascular events and hypersensitivity reactions that pose problem in differential diagnosis and therapy. We present a 14 year-old female with polycystic ovary syndrome taking oral contraceptive and suffering from recurrent coronary ischemic attacks with increased eosinophils, and troponin levels suggesting Kounis syndrome.
authors.affiliation: Nurdan Erol, Siyami Ersek Thorax and Cardiovascular Surgery Training and Research Hospital, Pediatric Cardiology Clinic, 34668 Uskudar, Istanbul, Turkey.
authors.forename: Nurdan
authors.initials: N
authors.lastname: Erol
authors.affiliation: Nurdan Erol, Siyami Ersek Thorax and Cardiovascular Surgery Training and Research Hospital, Pediatric Cardiology Clinic, 34668 Uskudar, Istanbul, Turkey.
authors.forename: Aysu Turkmen
authors.initials: AT
authors.lastname: Karaagac
authors.affiliation: Nurdan Erol, Siyami Ersek Thorax and Cardiovascular Surgery Training and Research Hospital, Pediatric Cardiology Clinic, 34668 Uskudar, Istanbul, Turkey.
authors.forename: Nicholas G
authors.initials: NG
authors.lastname: Kounis
keywords: Contraceptives; Eosinophils; Kounis syndrome; Polycystic ovary syndrome; Troponin