title: Anterior cervical disc replacement for degenerative disc disease.
abstract: OBJECTIVE
  To review the outcomes of anterior cervical disc replacement using the Prestige LP system for degenerative disc disease.
  
  
  METHODS
  Medical records of 12 men and 23 women aged 26 to 66 (mean, 46) years who underwent 48 anterior cervical disc replacements using the Prestige LP system by a single spine surgeon were reviewed. 22 patients underwent one-level disc replacement at C5-C6 (n=13) and C6-C7 (n=9), and 13 patients underwent 2-level disc replacement at C5-C6 and C6-C7 (n=11), C4-C5 and C5-C6 (n=1), and C6-C7 and C7-T1 (n=1). Neck Disability Index (NDI) score, visual analogue scale (VAS) for pain in the neck and arm, and physical and mental component scores of the Short Form 36 were evaluated at week 6 and months 6, 12, 24, 36, and 48.
  
  
  RESULTS
  The NDI score, VAS score for neck and arm pain, and physical and mental component scores of the Short Form 36 improved significantly after surgery (p<0.001). 80% of patients were satisfied with the treatment. One patient developed a neck haematoma on day 1 and underwent surgical evacuation. Another patient developed Horner's syndrome and achieved partial recovery at 6 weeks and complete recovery at 6 months. No patient had implant-related complications or reoperation.
  
  
  CONCLUSIONS
  The Prestige LP cervical disc implant was safe for one- and 2-level cervical disc replacement.
authors.affiliation: Spine Service, Department of Trauma and Orthopaedic Surgery, Galway University Hospitals, Newcastle Road, Galway, Ireland.
authors.forename: Sudarshan
authors.initials: S
authors.lastname: Munigangaiah
authors.forename: John P
authors.initials: JP
authors.lastname: McCabe
mesh_terms: D000328:Adult; D002574:Cervical Vertebrae / Q000601:surgery*; D005260:Female; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D059145:Total Disc Replacement / Q000295:instrumentation*
keywords: intervertebral disc degeneration; total disc replacement