title: Crystal structure of (±)-3-[(benzo[d][1,3]dioxol-5-yl)meth-yl]-2-(3,4,5-tri-meth-oxy-phen-yl)-1,3-thia-zolidin-4-one.
abstract: In the title thia-zolidine-4-one derivative, C20H21NO6S, the central thia-zolidine ring is essentially planar (r.m.s. deviation for all non-H atoms = 0.0287 Å) and forms a dihedral angle of 88.25 (5)° with the meth-oxy-substituted benzene ring and 74.21 (4)° with the 1,3-benzodioxole ring. The heterocyclic ring (with two O atoms) fused to benzene ring adopts an envelope conformation with the non-ring-junction C atom as the flap. In the crystal, the mol-ecules are linked into chains along [001] through weak C-H⋯O inter-actions, forming R (4) 4(28) edge-fused rings.
authors.affiliation: Departamento de Química, Facultad de Ciencias Naturales y Exactas, Universidad del Valle, AA 25360, Santiago de Cali, Colombia.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Moreno-Fuquen
authors.affiliation: Departamento de Química, Facultad de Ciencias Naturales y Exactas, Universidad del Valle, AA 25360, Santiago de Cali, Colombia.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Castillo
authors.affiliation: Departamento de Química, Facultad de Ciencias Naturales y Exactas, Universidad del Valle, AA 25360, Santiago de Cali, Colombia.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Abonia
authors.affiliation: Instituto de Física de São Carlos, IFSC, Universidade de São Paulo, USP, São Carlos, SP, Brazil.
authors.forename: Javier
authors.initials: J
authors.lastname: Ellena
authors.affiliation: Instituto de Física de São Carlos, IFSC, Universidade de São Paulo, USP, São Carlos, SP, Brazil.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: De Simone
keywords: 1,3-thia­zolidin-4-one; benzo[d][1,3]dioxole; biological properties; crystal structure; hydrogen bonding; pharmacological properties