title: Catalytic asymmetric construction of pyrroloindolines via an in situ generated magnesium catalyst.
abstract: An asymmetric formal [3 + 2]-cycloaddition between meso-aziridines and C3-alkylindoles mediated by an in situ generated magnesium catalyst was developed for asymmetric construction of pyrroloindolines. A variety of pyrroloindolines could be obtained by employing commercial available ligands with the assistance of an easily prepared achiral ligand.
authors.affiliation: School of Pharmaceutical Sciences, Sun Yat-sen University , Guangzhou 510006, P.R. China.
authors.forename: Linqing
authors.initials: L
authors.lastname: Wang
authors.forename: Dongxu
authors.initials: D
authors.lastname: Yang
authors.forename: Fengxia
authors.initials: F
authors.lastname: Han
authors.forename: Dan
authors.initials: D
authors.lastname: Li
authors.forename: Depeng
authors.initials: D
authors.lastname: Zhao
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
mesh_terms: D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008024:Ligands; D008274:Magnesium / Q000737:chemistry*; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D001388:Aziridines; D007211:Indoles; D008024:Ligands; D011758:Pyrroles; C511200:hexahydropyrrolo(2,3-b)indole; D008274:Magnesium