title: Optimizing individual treatment outcomes in men with lower urinary tract symptoms using storage subscale score/total International Prostate Symptom Score (IPSS) as a new IPSS ratio.
abstract: OBJECTIVE
  To evaluate the effects of the storage/total International Prostate Symptom Score (s/T) ratio on the selection and success of medical therapy in men with lower urinary tract symptoms (LUTS).
  
  
  METHODS
  A total of 54 men (>45 years of age) with moderate or severe LUTS were divided into 2 groups according to the s/T ratio: Group 1 at <0.43 and Group 2 at >0.43. Tamsulosin (0.4 mg to Group 1) and tolterodine ER (4 mg to Group 2) were administered. Patients were evaluated during the 1st and 3rd months of follow-up treatment.
  
  
  RESULTS
  Thirty-seven (68.5%) and 17 (31.5%) patients were in Groups 1 and 2, respectively. The mean s/T ratios in Groups 1 and 2 increased to 0.38 ± 0.19 from 0.33 ± 0.08 (P = 0.03) and decreased to 0.54 ± 0.18 from 0.59 ± 0.1 (P = 0.17) during the 3rd month of follow-up, respectively. The treatment success rates of Groups 1 and 2 were 88.4% and 75.7%, respectively. Nine unsuccessful cases were treated with combination therapy and the treatment success was 86.6% at follow-up.
  
  
  CONCLUSIONS
  The s/T ratio is effective to determine symptom dominance in men with LUTS and can guide medical treatment selection through better identification of symptoms.
authors.affiliation: Department of Urology, Pamukkale University, Denizli, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Altintaş
authors.forename: Ismail Cenk
authors.initials: IC
authors.lastname: Acar
authors.forename: Saadettin Yılmaz
authors.initials: SY
authors.lastname: Eskiçorapçi
authors.forename: Ali Ersin
authors.initials: AE
authors.lastname: Zümrütbaş
authors.forename: Deniz
authors.initials: D
authors.lastname: Bolat
authors.forename: Ömer Levent
authors.initials: ÖL
authors.lastname: Tuncay
authors.forename: Mehmet Zafer
authors.initials: MZ
authors.lastname: Sinik
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000368:Aged; D000465:Algorithms; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D018727:Muscarinic Antagonists / Q000627:therapeutic use; D018579:Patient Selection; D011446:Prospective Studies; D001748:Urinary Bladder Neck Obstruction / Q000175:diagnosis; D053201:Urinary Bladder, Overactive / Q000175:diagnosis
chemical_list: D000317:Adrenergic alpha-Antagonists; D018727:Muscarinic Antagonists