title: [Postural orthostatic tachycardia syndrome (POTS)--pathophysiology, diagnostics, and treatment].
abstract: Postural orthostatic tachycardia syndrome (POTS) is one of the most common presentation of orthostatic intolerance. The syndrome is described as a multifactorial affliction. Main symptoms consist of persistent orthostatic tachycardia (heart rate increase at least 30 beats/min, lasting at least 10 min after assumic vertical position) with high noradrenalin serum concentration (measured in stand-up position). Additionally patients with POTS tend to have lover total blood volume. POTS is generally classified into dysatonomia disorders Symptoms in patients affected with POTS are chronic. The syndrome occurs predominantly in young women (approximately 80%). Due to complexity and variable intensity of symptoms POTS can severely impair daily activity and quality of life in otherwise healthy people. The correct diagnosis and identification of potential pathophysiological mechanisms of POTS is necessary before treatment administration. Adequate therapy can significantly reduce symptoms giving the patients a chance for a normal life.
authors.forename: Marta
authors.initials: M
authors.lastname: Rek
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Kaczmarek
authors.forename: Iwona
authors.initials: I
authors.lastname: Cygankiewicz
authors.forename: Jerzy K
authors.initials: JK
authors.lastname: Wranicz
authors.forename: Paweł
authors.initials: P
authors.lastname: Ptaszyński
mesh_terms: D015897:Comorbidity; D005260:Female; D006801:Humans; D020896:Hypovolemia / Q000453:epidemiology; D015994:Incidence; D008297:Male; D054972:Postural Orthostatic Tachycardia Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology / Q000628:therapy*; D011788:Quality of Life; D017678:Sex Distribution; D012737:Sex Factors; D018667:Tilt-Table Test