title: Transition Metals Catalyzed Element-Cyano Bonds Activations.
abstract: Cyano group as a versatile functionalized intermediate has been explored for several decades, as it readily transfers to many useful functionalization groups such as amine, amide, acid, etc., which make it possess high popularization and use value in organic synthesis. Reactions involved with element-cyano bond cleavage can provide not only a new cyano group but also a freshly functionalized skeleton in one-pot, consequently making it of high importance. The highlights reviewed herein include H-CN, Si-CN, C-CN, B-CN, Sn-CN, Ge-CN, S-CN, Halo-CN, N-CN, and O-CN bonds cleavages and will summarize progress in such an important research area. This review article will focus on transition metal catalyzed reactions involving element-cyano bond activation.
authors.affiliation: Department of Biochemistry, Division of Chemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA ; Department of Chemistry, State University of New York at Albany, Albany, New York, USA.
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.affiliation: Department of Biochemistry, Division of Chemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
authors.forename: John R
authors.initials: JR
authors.lastname: Falck
keywords: Bond activation; Carbon-carbon formation; Dehydrogenative coupling reactions; Elements-cyano; Transition metals