title: The utilization of copper flow reactors in organic synthesis.
abstract: The use of flow chemistry techniques has flourished over the past decade, with the field expanding to include the use of copper flow reactors in bench-top organic synthesis in recent years. These reactors are available in a variety of forms and possess a number of advantages over their batch reaction counterparts, in terms of both safety and yield. This review will highlight the current research employing copper flow reactors, such as 1,3-dipolar cycloadditions ('click' chemistry), macrocyclizations (via 'click' chemistry), Sonogashira C-C couplings, Ullmann couplings, decarboxylations, and other reported findings.
authors.affiliation: Faculty of Pharmacy, University of Manitoba, Winnipeg, MB R3E 0T5, Canada. geoffrey.tranmer@umanitoba.ca.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Bao
authors.forename: Geoffrey K
authors.initials: GK
authors.lastname: Tranmer
mesh_terms: D060326:Chemistry Techniques, Synthetic; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D061565:Cycloaddition Reaction
chemical_list: D003300:Copper