title: Baclofen in the short-term maintenance treatment of benzodiazepine dependence.
abstract: Benzodiazepine (BZD) dependence is a significant public health problem. Apart from the long-term tapering doses of BZD, no others drugs are available for the maintenance treatment of BZD dependence. Baclofen has been used in alcohol and other drug dependence as long-term anti-craving agent. Since alcohol and BZD act through the GABA receptor, we attempted to study the effect of Baclofen as maintenance treatment in a series of five cases with BZD dependence.
authors.affiliation: Department of Psychiatry, Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
authors.forename: Lekhansh
authors.initials: L
authors.lastname: Shukla
authors.affiliation: Department of Psychiatry, Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Kandasamy
authors.affiliation: Department of Psychiatry, Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
authors.forename: Muralidharan
authors.initials: M
authors.lastname: Kesavan
authors.affiliation: Department of Psychiatry, Centre for Addiction Medicine, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
authors.forename: Vivek
authors.initials: V
authors.lastname: Benegal
keywords: Anti-craving; baclofen; benzodiazepines; dependence; gamma-aminobutyric acid B; maintenance