title: [Comparative analysis and clinical experience with osteoplastic materials materials based on non-demineralized bone collagen and artificial hydroxylapatite at the close of bone defects in ambulatory surgical dentistry].
abstract: BACKGROUND
  In the presence of bone defects during surgery is not always performed osteoptastic material replenishment defect that leads to a lengthening of the timing healing, bone regeneration, and treatment outcome. Application of osteoplastic materials allows for faster treatment outcomes, accelerate the regeneration of bone tissue in the area of the defect.
  
  
  OBJECTIVE
  To examine the effectiveness of materials based on non-demineralized bone collagen and artificial hydroxylapatite when filling bone defects in outpatient surgical practice dentistry.
  
  
  METHODS
  22 patients with bone defects of various localization using osteoplastic materials were examined and treated. In our study, two groups were allocated on the etiology of bone loss: radicular cysts and chronic generalized periodontitis. Basic methods of diagnosis and monitoring of treatment in the work presented with the cone-beam computed tomography and digital orthopantomography.
  
  
  RESULTS
  Application of the testing osteoplastic materials resulted in faster recovery times with a combination of bone defects using resorbable membranes or gel enriched fibrin. In all 22 patients both tested materials were well tolerated, allergic reactions were not identified. However, five patients with a history of endocrinological history, during which treatment material is applied on the basis non-demineralized bone collagen, the degree of osseointegration has been reduced by 25% compared to the somatic healthy patients. In 3 patients with a history of hematological history, during which the treatment was applied material on the basis of artificial hydroxyapatite, the regeneration of the bone defect was reduced by 20%, which suggests the influence of somatic condition of the patient on the regeneration of bone tissue. Currently, all patients are on dynamic monitoring, recurrence has been detected.
  
  
  CONCLUSIONS
  Materials based on non-demineralized bone collagen and hydroxyapatite artificial equally successful during the replacement of the bone defect during surgery. However, the degree of regeneration may be different if the patient has a history of aggeravated that should be considered when planning treatment.
authors.forename: M V
authors.initials: MV
authors.lastname: Dunaev
authors.forename: V A
authors.initials: VA
authors.lastname: Kitaev
authors.forename: M V
authors.initials: MV
authors.lastname: Matavkina
authors.forename: A E
authors.initials: AE
authors.lastname: Druzhinin
authors.forename: A S
authors.initials: AS
authors.lastname: Bubnov
mesh_terms: D000328:Adult; D001861:Bone Regeneration / Q000187:drug effects; D018786:Bone Substitutes / Q000494:pharmacology; D001842:Bone and Bones / Q000473:pathology; D003094:Collagen / Q000494:pharmacology*; D003764:Dental Materials / Q000494:pharmacology; D003814:Dentistry, Operative / Q000295:instrumentation / Q000379:methods; D017886:Durapatite / Q000494:pharmacology*; D005260:Female; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D008297:Male; D008422:Materials Testing / Q000379:methods; D009059:Mouth Diseases / Q000473:pathology / Q000601:surgery*; D016348:Osseointegration / Q000187:drug effects; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D018786:Bone Substitutes; D003764:Dental Materials; D003094:Collagen; D017886:Durapatite