title: Heterolytic activation of dihydrogen molecule by hydroxo-/sulfido-bridged ruthenium-germanium dinuclear complex. Theoretical insights.
abstract: Heterolytic activation of dihydrogen molecule (H2) by hydroxo-/sulfido-bridged ruthenium-germanium dinuclear complex [Dmp(Dep)Ge(μ-S)(μ-OH)Ru(PPh3)](+) (1) (Dmp = 2,6-dimesitylphenyl, Dep = 2,6-diethylphenyl) is theoretically investigated with the ONIOM(DFT:MM) method. H2 approaches 1 to afford an intermediate [Dmp(Dep)(HO)Ge(μ-S)Ru(PPh3)](+)-(H2) (2). In 2, the Ru-OH coordinate bond is broken but H2 does not yet coordinate with the Ru center. Then, the H2 further approaches the Ru center through a transition state TS2-3 to afford a dihydrogen σ-complex [Dmp(Dep)(HO)Ge(μ-S)Ru(η(2)-H2)(PPh3)](+) (3). Starting from 3, the H-H σ-bond is cleaved by the Ru and Ge-OH moieties to form [Dmp(Dep)(H2O)Ge(μ-S)Ru(H)(PPh3)](+) (4). In 4, hydride and H2O coordinate with the Ru and Ge centers, respectively. Electron population changes clearly indicate that this H-H σ-bond cleavage occurs in a heterolytic manner like H2 activation by hydrogenase. Finally, the H2O dissociates from the Ge center to afford [Dmp(Dep)Ge(μ-S)Ru(H)(PPh3)](+) (PRD). This step is rate-determining. The activation energy of the backward reaction is moderately smaller than that of the forward reaction, which is consistent with the experimental result that PRD reacts with H2O to form 1 and H2. In the Si analogue [Dmp(Dep)Si(μ-S)(μ-OH)Ru(PPh3)](+) (1Si), the isomerization of 1Si to 2Si easily occurs with a small activation energy, while the dissociation of H2O from the Si center needs a considerably large activation energy. Based on these computational findings, it is emphasized that the reaction of 1 resembles well that of hydrogenase and the use of Ge in 1 is crucial for this heterolytic H-H σ-bond activation.
authors.affiliation: Department of Molecular Engineering, Graduate School of Engineering, Kyoto University , Nishikyo-ku, Kyoto 610-8510, Japan.
authors.forename: Noriaki
authors.initials: N
authors.lastname: Ochi
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Takeya
authors.initials: T
authors.lastname: Dei
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Nakao
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Sato
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Tatsumi
authors.forename: Shigeyoshi
authors.initials: S
authors.lastname: Sakaki