title: Next-generation strategies for hereditary colorectal cancer risk assessment.
authors.affiliation: Dana-Farber Cancer Institute, Boston, MA matthew_yurgelun@dfci.harvard.edu.
authors.forename: Matthew B
authors.initials: MB
authors.lastname: Yurgelun
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D000236:Adenoma / Q000175:diagnosis; D000328:Adult; D014408:Biomarkers, Tumor / Q000235:genetics*; D003113:Colonoscopy; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000628:therapy; D045647:DNA Glycosylases / Q000235:genetics*; D055088:Early Detection of Cancer / Q000379:methods; D005260:Female; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D007150:Immunohistochemistry; D009154:Mutation; D010375:Pedigree; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D016283:Proto-Oncogene Proteins p21(ras); D018570:Risk Assessment; D012307:Risk Factors; D018631:ras Proteins / Q000235:genetics*
chemical_list: D014408:Biomarkers, Tumor; C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; D045647:DNA Glycosylases; C061738:mutY adenine glycosylase; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins