title: Complexation of estragole as pure compound and as main component of basil and tarragon essential oils with cyclodextrins.
abstract: Inclusion complexes of estragole (ES) as pure compound and as main component of basil and tarragon essential oils (EOs) with α-cyclodextrin (α-CD), β-cyclodextrin (β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD), randomly methylated-β-cyclodextrin (RAMEB), a low methylated-β-cyclodextrin (CRYSMEB) and γ-cyclodextrin (γ-CD) were characterized. Formation constants (Kf) of the complexes were determined in aqueous solution by nonlinear regression analysis using static headspace gas chromatography (SH-GC) and UV-visible spectroscopy. Solid inclusion complexes were prepared by the freeze-drying method for different CD:ES molar ratios and were characterized by differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FT-IR). Inclusion complexes formation allowed the controlled release of ES. Moreover, increased DPPH radical scavenging activity and photostability of ES and ES containing EOs (ESEOs) were observed in the presence of CDs. These findings suggest that encapsulation with CDs could be an efficient tool to improve the use of ES and ESEOs in aromatherapy, cosmetic and food fields.
authors.affiliation: Bioactive Molecules Research Group, Doctoral School of Science and Technology, Department of Chemistry and Biochemistry, Faculty of Sciences-2, Lebanese University, Fanar, Lebanon; Unité de Chimie Environnementale et Interactions sur le Vivant (UCEIV), ULCO, F-59140 Dunkerque, France.
authors.forename: Miriana
authors.initials: M
authors.lastname: Kfoury
authors.affiliation: Bioactive Molecules Research Group, Doctoral School of Science and Technology, Department of Chemistry and Biochemistry, Faculty of Sciences-2, Lebanese University, Fanar, Lebanon.
authors.forename: Lizette
authors.initials: L
authors.lastname: Auezova
authors.affiliation: Unité de Chimie Environnementale et Interactions sur le Vivant (UCEIV), ULCO, F-59140 Dunkerque, France.
authors.forename: Steven
authors.initials: S
authors.lastname: Ruellan
authors.affiliation: Bioactive Molecules Research Group, Doctoral School of Science and Technology, Department of Chemistry and Biochemistry, Faculty of Sciences-2, Lebanese University, Fanar, Lebanon.
authors.forename: Hélène
authors.initials: H
authors.lastname: Greige-Gerges
authors.affiliation: Unité de Chimie Environnementale et Interactions sur le Vivant (UCEIV), ULCO, F-59140 Dunkerque, France. Electronic address: lamotte@univ-littoral.fr.
authors.forename: Sophie
authors.initials: S
authors.lastname: Fourmentin
mesh_terms: D000081248:Allylbenzene Derivatives; D000840:Anisoles / Q000737:chemistry*; D019306:Artemisia / Q000737:chemistry*; D002152:Calorimetry, Differential Scanning; D003505:Cyclodextrins / Q000737:chemistry; D018649:Ocimum basilicum / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D047391:alpha-Cyclodextrins / Q000737:chemistry; D047392:beta-Cyclodextrins / Q000737:chemistry; D047408:gamma-Cyclodextrins / Q000737:chemistry
chemical_list: D000081248:Allylbenzene Derivatives; D000840:Anisoles; D003505:Cyclodextrins; D009822:Oils, Volatile; D047391:alpha-Cyclodextrins; D047392:beta-Cyclodextrins; C121706:delta-cyclodextrin; D047408:gamma-Cyclodextrins; C007633:estragole; C031215:betadex; C023792:gamma-cyclodextrin; C032613:alpha-cyclodextrin
keywords: Cyclodextrins; DPPH(•) scavenging; Essential oils; Estragole; Formation constant; Photostability