title: Investigation of Salecan/poly(vinyl alcohol) hydrogels prepared by freeze/thaw method.
abstract: Salecan is a novel water-soluble extracellular-glucan produced by a new kind of salt-tolerant strain Agrobacterium sp. ZX09 and can be applied in food and medicine industries. In this work, Salecan (Sal) was incorporated into poly(vinyl alcohol) (PVA) to prepare novel Sal/PVA hybrid hydrogels by repeated freeze-thaw processing. Physicochemical and biological characteristics of the hydrogels were investigated to evaluate their potential as cell adhesion materials. By increasing the Salecan content in the hybrid hydrogels, their swelling capacity increased notably, while the compressive modulus decreased. Observed by SEM, Sal/PVA hydrogels had a homogeneous porous structure. The degradation rate of the hydrogels can be controlled by tailoring the composition ratio of Sal/PVA. Furthermore, cells could adhere well on the surface of Sal/PVA hydrogels. In conclusion, these results make Sal/PVA hydrogels attractive materials for biomedical applications.
authors.affiliation: Center for Molecular Metabolism, Nanjing University of Science & Technology, 200 Xiaolingwei Street, Nanjing 210094, China.
authors.forename: Xiaoliang
authors.initials: X
authors.lastname: Qi
authors.affiliation: Center for Molecular Metabolism, Nanjing University of Science & Technology, 200 Xiaolingwei Street, Nanjing 210094, China.
authors.forename: Xinyu
authors.initials: X
authors.lastname: Hu
authors.affiliation: Center for Molecular Metabolism, Nanjing University of Science & Technology, 200 Xiaolingwei Street, Nanjing 210094, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.affiliation: Center for Molecular Metabolism, Nanjing University of Science & Technology, 200 Xiaolingwei Street, Nanjing 210094, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Yu
authors.affiliation: Center for Molecular Metabolism, Nanjing University of Science & Technology, 200 Xiaolingwei Street, Nanjing 210094, China.
authors.forename: Junjian
authors.initials: J
authors.lastname: Li
authors.affiliation: Center for Molecular Metabolism, Nanjing University of Science & Technology, 200 Xiaolingwei Street, Nanjing 210094, China.
authors.forename: Jianfa
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Center for Molecular Metabolism, Nanjing University of Science & Technology, 200 Xiaolingwei Street, Nanjing 210094, China. Electronic address: dongwei@njust.edu.cn.
authors.forename: Wei
authors.initials: W
authors.lastname: Dong
mesh_terms: D005615:Freezing; D020100:Hydrogels / Q000737:chemistry*; D011142:Polyvinyl Alcohol / Q000737:chemistry*; D047071:beta-Glucans / Q000737:chemistry*
chemical_list: D020100:Hydrogels; D047071:beta-Glucans; C577623:salecan; D011142:Polyvinyl Alcohol
keywords: Freeze–thaw processing; Hybrid hydrogels; Poly(vinyl alcohol); Salecan