title: [Comparative investigation of rheological characteristics of the original drug Triderm and its generics in the form of cream].
abstract: Rheological properties of mild pharmaceutical formulations (creams) with glucocorticosteroids, such as Triderm (Belgium), Akriderm GK (Russia) and Kanizon plus (India) were studied. The study revealed differences in the structural-strength properties of the medicines (viscosity, critical shear stress). The necessity of rheological investigations during development of generic medicines was shown.
authors.forename: E I
authors.initials: EI
authors.lastname: Molokhova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Sorokina
mesh_terms: D001623:Betamethasone / Q000031:analogs & derivatives; D003022:Clotrimazole; D016568:Drugs, Generic / Q000032:analysis* / Q000737:chemistry; D005079:Excipients; D005839:Gentamicins; D006801:Humans; D012212:Rheology; D063465:Skin Cream / Q000032:analysis* / Q000737:chemistry; D014783:Viscosity
chemical_list: D016568:Drugs, Generic; D005079:Excipients; D005839:Gentamicins; C011175:betamethasone-17,21-dipropionate; D001623:Betamethasone; D003022:Clotrimazole