title: [Diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration in pulmonary sarcoidosis].
abstract: OBJECTIVE
  The aim of this study was to observe the diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in sarcoidosis.
  
  
  METHODS
  We retrospectively analyzed the diagnostic efficiency of standard bronchoscopy and EBUS-TBNA in all patients diagnosed as sarcoidosis in Peking University First Hospitals between August 2010 and October 2011. The relationship between biopsy puncture numbers and sensitivity was calculated.
  
  
  RESULTS
  There were 17 sarcoidosis patients among a total of 107 patients who had received EBUS-TBNA. Forteen patients had a positive TBNA result and the sensitive of EBUS-TBNA was 82%. The sensitivity of standard brochoscopy was 53% and when combined with EBUS-TBNA, the sensitivity increased to 88%. The sensitivity of EBUS-TBNA was associated with the size of lymph nodes. Lymph nodes with a diameter ≥ 2 cm showed a higher positive rate. Four punctures for 1 lymph node showed a concordance rate of 100% with the final results.
  
  
  CONCLUSIONS
  EBUS-TBNA was a safe and effective method in diagnosing pulmonary sarcoidosis. For patients with suspected sarcoidosis EBUS-TBNA should be performed in the largest lymph nodes with at least 4 punctures.
authors.affiliation: Department of Respiratory and Critical care Medicine, Department of Pathology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Email: wangguangfa@hotmail.com.
authors.forename: Guangfa
authors.initials: G
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Nan
authors.initials: N
authors.lastname: Li
authors.forename: Yunhong
authors.initials: Y
authors.lastname: Wang
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Gong
mesh_terms: D044963:Biopsy, Fine-Needle; D001707:Biopsy, Needle; D001999:Bronchoscopy; D006801:Humans; D061705:Image-Guided Biopsy; D008198:Lymph Nodes; D009339:Needles; D012189:Retrospective Studies; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis*; D018084:Ultrasonography, Interventional