title: Surgical management of metastatic melanoma in the era of targeted systemic therapies.
abstract: Treatment strategies for metastatic melanoma have changed markedly in recent times due to the advent of targeted systemic therapies. In addition to these developments, surgery remains a useful adjunct that can confer survival benefits in selected patients. In this review, we examine the current literature to highlight the role of surgical intervention in metastatic melanoma in the era of targeted systemic therapies.
authors.affiliation: Department of Surgery, Cork University Hospital, Cork, Ireland.
authors.forename: D Peter
authors.initials: DP
authors.lastname: O'Leary
authors.forename: Kevin G
authors.initials: KG
authors.lastname: Byrnes
authors.forename: Derek G
authors.initials: DG
authors.lastname: Power
authors.forename: H Paul
authors.initials: HP
authors.lastname: Redmond
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D003131:Combined Modality Therapy; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008495:Medical Oncology; D008545:Melanoma / Q000601:surgery*; D008938:Mitosis; D058990:Molecular Targeted Therapy; D009362:Neoplasm Metastasis; D010477:Perfusion; D012878:Skin Neoplasms / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D000911:Antibodies, Monoclonal