title: Minimal Clinically Important Difference of Grip and Pinch Strength in Women With Thumb Carpometacarpal Osteoarthritis When Compared to Healthy Subjects.
abstract: OBJECTIVE
  The primary objective of this study was to compare grip and pinch strength between women with carpometacarpal (CMC) osteoarthritis (OA) between affected and unaffected sides of the body in patients or dominant and nondominant sides in healthy subjects. The secondary aim was to establish the cutoff value scores for the minimal clinically important difference (MCID) for grip strength, tip, and tripod pinch.
  
  
  METHODS
  A prospective case-control study.
  
  
  METHODS
  One hundred ten women participated in the study. The CMC OA group consisted of 57 patients, and the control group consisted of 53 healthy subjects. Grip strength, tip, and tripod pinch were assessed bilaterally. The two-way analysis of variance (ANOVA) was conducted to determine the differences between sides of the body and between the groups.
  
  
  RESULTS
  The post hoc analysis indicated that the patients in the CMC OA group indicated statistically significant lower scores on the grip and pinch strength (all, p < .001). The MCID from baseline score in this patient population was 0.84 kg for grip, 0.33 kg for tip, and 0.35 kg for tripod pinch for the affected right arm and 1.12 kg for grip, 0.23 kg for tip, and 0.30 kg for tripod pinch for the unaffected left side.
  
  
  CONCLUSIONS
  Women with CMC OA have significantly decreased grip strength, tip, and tripod pinch as compared to their healthy counterparts and may experience functional consequences because of this limitation.
  
  
  CONCLUSIONS
  Our study established the MCID for grip and pinch strength for individuals with CMC OA and their healthy counterparts.
authors.affiliation: 1 IRCCS Don Gnocchi Foundation, Milan, Italy2 Hand Works Therapy, Sarasota, FL, USA3 School of Physical Therapy, Alma Mater Studiorum, University of Bologna, Bologna, Italy4 Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
authors.forename: Jorge Hugo
authors.initials: JH
authors.lastname: Villafañe
authors.forename: Kristin
authors.initials: K
authors.lastname: Valdes
authors.forename: Lucia
authors.initials: L
authors.lastname: Bertozzi
authors.forename: Stefano
authors.initials: S
authors.lastname: Negrini
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D052737:Carpometacarpal Joints / Q000002:abnormalities*; D016022:Case-Control Studies; D005260:Female; D018737:Hand Strength / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D000071081:Minimal Clinically Important Difference; D053580:Muscle Strength / Q000502:physiology*; D010003:Osteoarthritis / Q000150:complications* / Q000503:physiopathology / Q000534:rehabilitation; D052581:Pinch Strength / Q000502:physiology; D011446:Prospective Studies; D019145:Rehabilitation Nursing / Q000379:methods