title: Economic analysis of vaccination to control bovine brucellosis in the States of Sao Paulo and Mato Grosso, Brazil.
abstract: Brucellosis is a zoonotic disease that causes important economic losses in Brazil, and the country has therefore established a national program for its control and eradication. Using data generated in the last national brucellosis survey, we conducted an economic analysis in two Brazilian States with different brucellosis status, Mato Grosso (with high prevalence) and Sao Paulo (with low prevalence). The economic analysis was based on the calculation of the additional benefits and costs of controlling bovine brucellosis through the vaccination of heifers aged between 3 and 8 months with S19 vaccine, considering maximal and minimal impacts of the disease. The analysis showed that vaccinating 90% of the replacement heifers aged 3-8 months of age offers the best economic performance in a vaccination program against bovine brucellosis if compared to vaccination rates of 70% and 80%. Moreover, regions with higher prevalences of bovine brucellosis would experience significant economic advantages when implementing a vaccination strategy to control the disease. This economic analysis will allow decision makers to plan more economically effective vaccination programs.
authors.affiliation: Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of Sao Paulo, Brazil.
authors.forename: A J S
authors.initials: AJ
authors.lastname: Alves
authors.affiliation: Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of Sao Paulo, Brazil.
authors.forename: F
authors.initials: F
authors.lastname: Rocha
authors.affiliation: Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of Sao Paulo, Brazil.
authors.forename: M
authors.initials: M
authors.lastname: Amaku
authors.affiliation: Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of Sao Paulo, Brazil.
authors.forename: F
authors.initials: F
authors.lastname: Ferreira
authors.affiliation: Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of Sao Paulo, Brazil.
authors.forename: E O
authors.initials: EO
authors.lastname: Telles
authors.affiliation: Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of Sao Paulo, Brazil.
authors.forename: J H H
authors.initials: JH
authors.lastname: Grisi Filho
authors.affiliation: Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of Sao Paulo, Brazil.
authors.forename: J S
authors.initials: JS
authors.lastname: Ferreira Neto
authors.affiliation: Department of Business, School of Economics, Business and Accounting, University of Sao Paulo, Brazil.
authors.forename: D
authors.initials: D
authors.lastname: Zylbersztajn
authors.affiliation: Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of Sao Paulo, Brazil. Electronic address: dias@vps.fmvz.usp.br.
authors.forename: R A
authors.initials: RA
authors.lastname: Dias
mesh_terms: D000822:Animal Husbandry / Q000191:economics* / Q000379:methods; D000818:Animals; D001428:Bacterial Vaccines / Q000191:economics* / Q000627:therapeutic use; D001938:Brazil / Q000453:epidemiology; D002007:Brucellosis, Bovine / Q000191:economics / Q000453:epidemiology / Q000517:prevention & control*; D002417:Cattle; D003198:Computer Simulation; D003362:Cost-Benefit Analysis; D005260:Female; D014611:Vaccination / Q000191:economics / Q000662:veterinary*
chemical_list: D001428:Bacterial Vaccines
keywords: Bovine; Brucellosis; Economic analysis; Vaccination