title: A case of refractory chronic neutrophilic pustular folliculitis treated with adalimumab.
abstract: Neutrophilic folliculitis is an often overlooked chronic condition characterized by a monomorphic eruption of "sterile" papulopustules. Neutrophilic folliculitis is often refractory to conventional treatment with topical and systemic antibiotics or isotretinoin. We report a case of severe pustular neutrophilic folliculitis successfully treated with the tumor necrosis factor-alpha inhibitor adalimumab.
authors.affiliation: Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Freja Laerke
authors.initials: FL
authors.lastname: Sand
authors.forename: Simon Francis
authors.initials: SF
authors.lastname: Thomsen
mesh_terms: D000068879:Adalimumab / Q000627:therapeutic use*; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D005499:Folliculitis / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007960:Leukocyte Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D008297:Male; D009504:Neutrophils / Q000187:drug effects* / Q000276:immunology / Q000473:pathology; D012074:Remission Induction; D012867:Skin / Q000187:drug effects* / Q000276:immunology / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000276:immunology
chemical_list: D000893:Anti-Inflammatory Agents; D014409:Tumor Necrosis Factor-alpha; D000068879:Adalimumab
keywords: inflammatory disorders; therapy- systemic