title: Clinical application of exhaled nitric oxide measurements in a korean population.
abstract: Nitric oxide (NO) is a biologic mediator of various physiologic functions. Recent evidence suggests the clinical utility of fractional exhaled NO (FeNO) as a biomarker for assessing asthma and other respiratory diseases. FeNO methodologies have been recently standardized by international research groups and subsequently validated in several Korean population studies. Normal ranges for FeNO have been reported for various ethnic groups, and the clinical utility has been widely evaluated in asthma and various respiratory diseases. Based on current evidence including most of Korean population data, this position paper aims to introduce the methodological considerations, and provide the guidance for the proper clinical application of FeNO measurements in Korean populations.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Woo-Jung
authors.initials: WJ
authors.lastname: Song
authors.affiliation: Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Ji-Won
authors.initials: JW
authors.lastname: Kwon
authors.affiliation: Allergy TF, Department of Immunology and Pathology, Korea National Institute of Health, Cheongwon, Korea.
authors.forename: Eun-Jin
authors.initials: EJ
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.
authors.forename: Sang-Min
authors.initials: SM
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Sae-Hoon
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Suwon, Korea.
authors.forename: So-Yeon
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: Sang-Heon
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Heung-Woo
authors.initials: HW
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. ; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Yoon-Seok
authors.identifier: 0000-0003-3157-0447
authors.initials: YS
authors.lastname: Chang
authors.affiliation: Department of Pediatrics, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Woo Kyung
authors.identifier: 0000-0001-8730-010X
authors.initials: WK
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Jung Yeon
authors.initials: JY
authors.lastname: Shim
authors.affiliation: Department of Pediatrics, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Ju-Hee
authors.initials: JH
authors.lastname: Seo
authors.affiliation: Department of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea.
authors.forename: Byoung-Ju
authors.initials: BJ
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Hae-undae Paik Hospital, Inje University College of Medicine, Busan, Korea.
authors.forename: Hyo Bin
authors.initials: HB
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
authors.forename: Dae Jin
authors.initials: DJ
authors.lastname: Song
authors.affiliation: Department of Pediatrics, National Health Insurance Corporation Ilsan Hospital, Goyang, Korea.
authors.forename: Gwang Cheon
authors.initials: GC
authors.lastname: Jang
authors.affiliation: Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
authors.forename: An-Soo
authors.initials: AS
authors.lastname: Jang
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jung-Won
authors.initials: JW
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: Ho-Joo
authors.initials: HJ
authors.lastname: Yoon
authors.affiliation: Allergy TF, Department of Immunology and Pathology, Korea National Institute of Health, Cheongwon, Korea.
authors.forename: Joo-Shil
authors.initials: JS
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Sang-Heon
authors.initials: SH
authors.lastname: Cho
authors.affiliation: Department of Pediatrics, Childhood Asthma Atopy Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Soo-Jong
authors.initials: SJ
authors.lastname: Hong
keywords: Exhaled nitric oxide; asthma; guideline; position paper; reference value