title: Neck circumference and prehypertension: the cardiometabolic risk in Chinese study.
abstract: BACKGROUND
  We have previously found that neck circumference was related to insulin resistance, a risk factor for hypertension in Chinese. Little is known about whether high neck circumference is associated with elevated blood pressure.
  
  
  METHODS
  The study samples were from a community-based health examination survey in central China. In total, 1709 men and women with neck circumference measurement were included. We analysed the associations between neck circumference and the risk of prehypertension.
  
  
  RESULTS
  Although neck circumference was strongly associated with SBP/DBP in a univariate analysis, it was no longer associated with SBP and the association was much weaker with DBP when the association was adjusted for BMI or waist circumference. Similarly, high neck circumference was significantly related to an increased risk of prehypertension [odds ratio 1.254; 95% confidence interval (95% CI) 1.171-1.343] in a univariate analysis, and the association became marginal in models further adjusting for BMI or waist.
  
  
  CONCLUSIONS
  Our data suggest that neck circumference as predictor for prehypertension is not obvious given the moderate improvement of disease prediction.
authors.affiliation: aDepartment of Endocrinology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical College, Xuzhou Institute of Medical Sciences, Xuzhou Institute of Diabetes, Affiliated Hospital of Southeast University bXuzhou Medical College, Xuzhou, Jiangsu, China cDepartment of Nutrition, Harvard School of Public Health dChanning Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA *Both Jun Liang and Yu Wang contributed equally to this work.
authors.forename: Jun
authors.initials: J
authors.lastname: Liang
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
authors.forename: Lianjun
authors.initials: L
authors.lastname: Dou
authors.forename: Hongyan
authors.initials: H
authors.lastname: Li
authors.forename: Xuekui
authors.initials: X
authors.lastname: Liu
authors.forename: Qinqin
authors.initials: Q
authors.lastname: Qiu
authors.forename: Lu
authors.initials: L
authors.lastname: Qi
mesh_terms: D000328:Adult; D044466:Asian People; D015415:Biomarkers; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D005260:Female; D006306:Health Surveys; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D009333:Neck; D016017:Odds Ratio; D058246:Prehypertension / Q000453:epidemiology*; D012307:Risk Factors; D055105:Waist Circumference
chemical_list: D015415:Biomarkers