title: Ceramic-on-ceramic total hip arthroplasty in patients younger than 55 years.
abstract: OBJECTIVE
  To review the outcomes of 65 patients younger than 55 years who underwent uncemented total hip arthroplasty (THA) using third-generation ceramic-on-ceramic prostheses.
  
  
  METHODS
  Medical records of 30 men and 35 women (80 hips) aged 18 to 55 (mean, 39) years who underwent uncemented THA using third-generation ceramic-onceramic prostheses by a single surgeon were reviewed. 61 THAs used the Reflection cup with the Synergy stem (n=49), Spectron stem (n=7), or Anthology stem (n=5), and 19 THAs used the Trident cup with the Secur-Fit stem. Outcomes were assessed based on the UCLA Activity Score and Harris Hip Score, as well as radiolucency around the implants, malposition, and subsidence on radiographs. Patients were asked about their satisfaction with current activity level (yes/no), activity limitation (no limitation, musculoskeletal limitation, psychological impediments and lack of motivation, and pain or disability of the operative hip), and change in occupational activity level (same or similar, more active, and less active or disability).
  
  
  RESULTS
  The mean follow-up period was 54 (range, 24-110) months. Six patients were excluded from the analysis owing to prosthetic failure secondary to ceramic liner fracture after falling (n=2), acetabular component loosening (n=1), intolerable squeak (n=1), periprosthetic fracture (n=1), and instability (n=1). The mean UCLA Activity Score improved from 4.0 (range, 1-10) to 7.7 (range, 2-10) [p<0.001], and the mean Harris Hip Score improved from 52.8 (range, 25-69) to 91.0 (range, 38-100) [p<0.001]. No hip had evidence of subsidence, loosening, or osteolysis. 52 (80%) patients were satisfied with their activity level; 28 (43%) patients reported no activity limitation; and 57 (88%) patients kept the same or similar occupation.
  
  
  CONCLUSIONS
  Ceramic-on-ceramic THA achieved acceptable clinical and radiographic outcomes.
authors.affiliation: Department of Orthopaedics, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Roshan P
authors.initials: RP
authors.lastname: Shah
authors.affiliation: Department of Orthopaedics, University of California, Irvine, CA, USA.
authors.forename: John A
authors.initials: JA
authors.lastname: Scolaro
authors.affiliation: Greater Pittsburgh Orthopaedic Associates, Sewickley, PA, USA.
authors.forename: Roger
authors.initials: R
authors.lastname: Componovo
authors.affiliation: Premiere Orthopaedics, Malvern, PA, USA.
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Garino
authors.affiliation: Department of Orthopaedics, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Gwo-Chin
authors.initials: GC
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D019644:Arthroplasty, Replacement, Hip; D001672:Biocompatible Materials; D002516:Ceramics; D005260:Female; D006621:Hip Joint / Q000601:surgery*; D006622:Hip Prosthesis; D006801:Humans; D007592:Joint Diseases / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D001672:Biocompatible Materials
keywords: arthroplasty, replacement, hip; ceramics