title: Can Plateletcrit be a Marker for Recurrent Pregnancy Loss?
abstract: OBJECTIVE
  To determine the utility of platelet (PLT) indices for the prediction of recurrent pregnancy loss (RPL).
  
  
  METHODS
  In all, 208 patients who experienced 2 or more first trimester spontaneous abortions and 95 controls who had no abortions were studied. The hematological markers, including plateletcrit (PCT) and neutrophil (Neu) to lymphocyte (Lym) ratio (NLR), were measured. Thrombophilia genetic tests for factor V Leiden mutation, prothrombin G202I0A mutation, and methylenetetrahydrofolate reductase C677 T and A1298C mutations were performed.
  
  
  RESULTS
  The PLT count, PCT, white blood cell count, red cell distribution width (RDW), Lym and Neu count, and NLR were significantly higher in patients with RPL than in controls. The RDW, PLT, and PCT values were higher in the low-risk group, whereas mean PLT volume values were lower than the high-risk group values.
  
  
  CONCLUSIONS
  Plateletcrit is a low-cost, widely available marker for prediction of RPL in patients with a history of at least 1 abortus.
authors.affiliation: Department of Gynecology and Obstetrics, Faculty of Medicine, Bülent Ecevit University, Zonguldak, Turkey.
authors.forename: Oner
authors.initials: O
authors.lastname: Aynıoglu
authors.affiliation: Department of Gynecology and Obstetrics, Faculty of Medicine, Bülent Ecevit University, Zonguldak, Turkey k.hgonbe@gmail.com.
authors.forename: Hatice
authors.initials: H
authors.lastname: Isık
authors.affiliation: Department of Gynecology and Obstetrics, Faculty of Medicine, Bülent Ecevit University, Zonguldak, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Sahbaz
authors.affiliation: Department of Gynecology and Obstetrics, Faculty of Medicine, Bülent Ecevit University, Zonguldak, Turkey.
authors.forename: Mehmet I
authors.initials: MI
authors.lastname: Harma
authors.affiliation: Department of Romatology, Faculty of Medicine, Bülent Ecevit University, Zonguldak, Turkey.
authors.forename: Metin
authors.initials: M
authors.lastname: Isık
authors.affiliation: Department of Biostatistics, Faculty of Medicine, Bülent Ecevit University, Zonguldak, Turkey.
authors.forename: Furuzan
authors.initials: F
authors.lastname: Kokturk
mesh_terms: D000026:Abortion, Habitual / Q000097:blood* / Q000175:diagnosis*; D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006403:Hematologic Tests; D006801:Humans; D010976:Platelet Count; D011237:Predictive Value of Tests; D011247:Pregnancy; D012189:Retrospective Studies; D019851:Thrombophilia / Q000235:genetics
chemical_list: D015415:Biomarkers
keywords: clinical thrombophilia; hemostasis; recurrent abortion