title: Diagnosis and management of coronary allograft vasculopathy in children and adolescents.
abstract: Coronary allograft vasculopathy remains one of the leading causes of death beyond the first year post transplant. As a result of denervation following transplantation, patients lack ischaemic symptoms and presentation is often late when the graft is already compromised. Current diagnostic tools are rather invasive, or in case of angiography, significantly lack sensitivity. Therefore a non-invasive tool that could allow early diagnosis would be invaluable.This paper review the disease form its different diagnosis techniques,including new and less invasive diagnostic tools to its pharmacological management and possible treatments.
authors.affiliation: Nathalie Dedieu, Matthew Fenton, Michael Burch, Great Ormond Street Hospital for Children NHS Foundation Trust, WC1 3JH London, United Kingdom.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Dedieu
authors.affiliation: Nathalie Dedieu, Matthew Fenton, Michael Burch, Great Ormond Street Hospital for Children NHS Foundation Trust, WC1 3JH London, United Kingdom.
authors.forename: Gerald
authors.initials: G
authors.lastname: Greil
authors.affiliation: Nathalie Dedieu, Matthew Fenton, Michael Burch, Great Ormond Street Hospital for Children NHS Foundation Trust, WC1 3JH London, United Kingdom.
authors.forename: James
authors.initials: J
authors.lastname: Wong
authors.affiliation: Nathalie Dedieu, Matthew Fenton, Michael Burch, Great Ormond Street Hospital for Children NHS Foundation Trust, WC1 3JH London, United Kingdom.
authors.forename: Matthew
authors.initials: M
authors.lastname: Fenton
authors.affiliation: Nathalie Dedieu, Matthew Fenton, Michael Burch, Great Ormond Street Hospital for Children NHS Foundation Trust, WC1 3JH London, United Kingdom.
authors.forename: Michael
authors.initials: M
authors.lastname: Burch
authors.affiliation: Nathalie Dedieu, Matthew Fenton, Michael Burch, Great Ormond Street Hospital for Children NHS Foundation Trust, WC1 3JH London, United Kingdom.
authors.forename: Tarique
authors.initials: T
authors.lastname: Hussain
keywords: Allograft vasculopathy; Cardiac transplantation; Diagnosis; Management which reflect the content of the study; Paediatrics