title: [Parenteral administration medicines: recommendations of preparation, administration and stability].
abstract: OBJECTIVE
  To develop recommendations for the preparation of parenteral drugs (MAP), to assess the transferability of their preparation, from nursing units in the hospital ward to the pharmacy service (SF).
  
  
  METHODS
  A table of stabilities of parenteral drugs included in the pharmacotherapeutic guideline was developed using the american and spanish guidelines. Information about MAP was collected (method of preparation, support, maintenance, validity, administration specifications and packaging) by consulting product technical sheets, pharmaceutical industries, literature review and databases.
  
  
  RESULTS
  After reviewing 209 drugs, a list of recommendations was developed. According to the data, MAP will be prepared as follows: 89 drugs will be prepared from SF, 62 drugs at nursing units because of its immediate administration requirement and 58 are already packed for its administration by the industry. Of these 62 drugs prepared a nursing units, 14 of them will be prepared in the following doses by the SF. Therefore, 48 drugs will be prepared at nursing units from the 209 parenteral drugs reviewed.
  
  
  CONCLUSIONS
  A standardized method of preparation, storage, administration and validity of MAP was established by the SF. The preparation of MAP in the SF extends its shelf life, by considering physicochemical stability, level of risk and product vulnerability to microbiological contamination. The information provided will contribute to a reduction of errors associated with the preparation and administration of MAP.
authors.affiliation: Servicio de Farmacia. Hospital Intermutual de Levante. Valencia.. mgaspar@hilevante.com.
authors.forename: M
authors.initials: M
authors.lastname: Gaspar Carreño
authors.affiliation: Servicio de Farmacia. Hospital Intermutual de Levante. Valencia.. forrico@hilevante.com.
authors.forename: F
authors.initials: F
authors.lastname: Torrico Martín
authors.affiliation: Servicio de Farmacia. Hospital Intermutual de Levante. Valencia.. lnovajarque@hilevante.com.
authors.forename: L
authors.initials: L
authors.lastname: Novajarque Sala
authors.affiliation: Departamento de Farmacia. CEU Universidad Cardenal Herrera. Valencia. Faculdade de Farmácia da Universidade do Porto. Porto. Portugal.. m_cruz91@hotmail.com.
authors.forename: M
authors.initials: M
authors.lastname: Batista Cruz
authors.affiliation: Departamento de Farmacia. CEU Universidad Cardenal Herrera. Valencia. Faculdade de Farmácia da Universidade do Porto. Porto. Portugal.. tixaribeiro@hotmail.com.
authors.forename: P
authors.initials: P
authors.lastname: Ribeiro Gonçalves
authors.affiliation: Hospital Universitario Dr. Peset. Valencia.. begonaportaoltra@gmail.com.
authors.forename: B
authors.initials: B
authors.lastname: Porta Oltra
authors.affiliation: Hospital Intermutual de Levante. Valencia.. jcsanchez@hilevante.com.
authors.forename: J C
authors.initials: JC
authors.lastname: Sánchez Santos
mesh_terms: D004339:Drug Compounding / Q000592:standards*; D004355:Drug Stability; D017408:Guidelines as Topic; D006801:Humans; D007263:Infusions, Parenteral / Q000592:standards*; D010607:Pharmacy Service, Hospital