title: Predictors of hyperlipidemia during the first half of pregnancy in Mexican women.
abstract: OBJECTIVE
  To determine the predictors of hypercholesterolemia and of hypertriglyceridemia during the first half of pregnancy in Mexican women.
  
  
  METHODS
  Cross-sectional comparative study of pregnant women with less than 21 weeks of gestational age.
  
  
  METHODS
  Demographic information, obstetric history, prepregnancy body mass index, cholesterol and triglycerides. Cross tabulations and multiple logistic regression were used for statistical analysis.
  
  
  RESULTS
  230 participants; 61 women with normal prepregnancy body mass index, 108 with overweight, and 61 with obesity. Dyslipidemia was defined as elevated cholesterol (>180 mg/dL) or triglycerides (>170 mg/dL). After adjusting by potential confounders, independent predictors of hypercholesterolemia included being overweight (OR=2.8, 95% CI 1.4-5.9), being obese (OR=3.7 95% CI 1.6-8.4) or being on the second trimester of pregnancy. The same predictors were found for hypertriglyceridemia, respectively OR=2.8, 95% CI 1.4-5.6, OR=2.9, 95% CI 1.3-6.5, OR=2.6, 95% CI 1.4-4.7.
  
  
  CONCLUSIONS
  Mexican women with prepregnancy overweight or obesity have greater risk of suffering hypercholesterolemia and hypertriglyceridemia during pregnancy. Women in the second trimester had higher levels of both lipids as compared to the first one. This is the first Mexican study that confirms the increase of lipids as gestational age progresses.
authors.affiliation: Unidad de Investigación, Hospital Materno Perinatal "Mónica Pretelini Sáenz", Instituto de Salud del Estado de México (ISEM). Estado de México. México.. adrisgamx@hotmail.com.
authors.forename: Adriana
authors.initials: A
authors.lastname: Garduño-Alanís
authors.affiliation: Facultad de Medicina, Universidad Autónoma del Estado de México (UAEMex). Estado de México. México.. adrisgamx@hotmail.com.
authors.forename: Gilberto
authors.initials: G
authors.lastname: Vázquez-de Anda
authors.affiliation: Centro de Investigación y Estudios Avanzados en Ciencias de la Salud. Facultad de Medicina, Universidad Autonoma del Estado de Mexico. Estado de Mexico. Mexico.. adrisgamx@hotmail.com.
authors.forename: Roxana
authors.initials: R
authors.lastname: Valdés-Ramos
authors.affiliation: Centro de Investigación en Ciencias Médicas de la Universidad Autónoma del Estado de México (UAEMex). Estado de México. México.. adrisgamx@hotmail.com.
authors.forename: Juan O
authors.initials: JO
authors.lastname: Talavera
authors.affiliation: Unidad de Investigación, Hospital Materno Perinatal "Mónica Pretelini Sáenz", Instituto de Salud del Estado de México (ISEM). Estado de México. México.. je_herrera44@hotmail.com.
authors.forename: Javier E
authors.initials: JE
authors.lastname: Herrera-Villalobos
authors.affiliation: Facultad de Medicina, Universidad Autónoma del Estado de México (UAEMex). Estado de México. México.. adrisgamx@hotmail.com.
authors.forename: Gerardo G
authors.initials: GG
authors.lastname: Huitrón-Bravo
authors.affiliation: Unidad de Investigación, Hospital Materno Perinatal "Mónica Pretelini Sáenz", Instituto de Salud del Estado de México (ISEM). Estado de México. México.. epidemiologist.researcher@gmail.com.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Hernández-Garduño
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000209:etiology*; D008055:Lipids / Q000097:blood; D008800:Mexico; D009765:Obesity / Q000150:complications; D050177:Overweight / Q000150:complications; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology*; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood; D055815:Young Adult
chemical_list: D008055:Lipids; D014280:Triglycerides