title: An azodye-rhodamine-based fluorescent and colorimetric probe specific for the detection of Pd(2+) in aqueous ethanolic solution: synthesis, XRD characterization, computational studies and imaging in live cells.
abstract: Azodye-rhodamine hybrid colorimetric fluorescent probe (L) has been designed and synthesized. The structure of L has been established based on single crystal XRD. It has been shown to act as a selective turn-on fluorescent chemosensor for Pd(2+) with >40 fold enhancement by exhibiting red emission among the other 27 cations studied in aqueous ethanol. The coordination features of the species of recognition have been computationally evaluated by DFT methods and found to have a distorted tetrahedral Pd(2+) center in the binding core. The probe (L) has been shown to detect Pd up to 0.45 μM at pH 7.4. Furthermore, the probe can be used to image Pd(2+) in living cells.
authors.affiliation: Department of Chemistry, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711103, West Bengal, India. akmahapatra@rediffmail.com.
authors.forename: Ajit Kumar
authors.initials: AK
authors.lastname: Mahapatra
authors.forename: Saikat Kumar
authors.initials: SK
authors.lastname: Manna
authors.forename: Kalipada
authors.initials: K
authors.lastname: Maiti
authors.forename: Sanchita
authors.initials: S
authors.lastname: Mondal
authors.forename: Rajkishor
authors.initials: R
authors.lastname: Maji
authors.forename: Debasish
authors.initials: D
authors.lastname: Mandal
authors.forename: Sukhendu
authors.initials: S
authors.lastname: Mandal
authors.forename: Md Raihan
authors.initials: MR
authors.lastname: Uddin
authors.forename: Shyamaprosad
authors.initials: S
authors.lastname: Goswami
authors.forename: Ching Kheng
authors.initials: CK
authors.lastname: Quah
authors.forename: Hoong-Kun
authors.initials: HK
authors.lastname: Fun
mesh_terms: D000818:Animals; D002413:Cations, Divalent / Q000032:analysis; D002522:Chlorocebus aethiops; D003124:Colorimetry; D000431:Ethanol / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D018613:Microscopy, Confocal; D008958:Models, Molecular; D061848:Optical Imaging; D010165:Palladium / Q000032:analysis*; D012235:Rhodamines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods; D014709:Vero Cells; D014867:Water / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D002413:Cations, Divalent; D005456:Fluorescent Dyes; D012235:Rhodamines; D014867:Water; D000431:Ethanol; D010165:Palladium