title: Basic mechanisms for adverse cardiovascular events associated with air pollution.
abstract: Air pollution is a significant cause of cardiovascular morbidity and mortality worldwide. Although the epidemiologic association between air pollution exposures and exacerbation of cardiovascular disease (CVD) is well established, the mechanisms by which these exposures promote CVD are incompletely understood. This review provides an overview of the components of air pollution, an overview of the cardiovascular effects of air pollution exposure, and a review of the basic mechanisms that are activated by exposure to promote CVD.
authors.affiliation: Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, USA.
authors.forename: Michael T
authors.initials: MT
authors.lastname: Chin
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects*; D000397:Air Pollution / Q000009:adverse effects*; D000818:Animals; D002318:Cardiovascular Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology / Q000378:metabolism / Q000503:physiopathology; D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D010316:Particle Size; D052638:Particulate Matter / Q000009:adverse effects*; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter