title: Automated differentiation between epileptic and nonepileptic convulsive seizures.
abstract: Our objective was the clinical validation of an automated algorithm based on surface electromyography (EMG) for differentiation between convulsive epileptic and psychogenic nonepileptic seizures (PNESs). Forty-four consecutive episodes with convulsive events were automatically analyzed with the algorithm: 25 generalized tonic-clonic seizures (GTCSs) from 11 patients, and 19 episodes of convulsive PNES from 13 patients. The gold standard was the interpretation of the video-electroencephalographic recordings by experts blinded to the EMG results. The algorithm correctly classified 24 GTCSs (96%) and 18 PNESs (95%). The overall diagnostic accuracy was 95%. This algorithm is useful for distinguishing between epileptic and psychogenic convulsive seizures.
authors.affiliation: Department of Clinical Neurophysiology, Danish Epilepsy Center, Dianalund, Denmark; Department of Clinical Neurophysiology, Aarhus University Hospital, Aarhus, Denmark.
authors.forename: Sándor
authors.initials: S
authors.lastname: Beniczky
authors.forename: Isa
authors.initials: I
authors.lastname: Conradsen
authors.forename: Mihai
authors.initials: M
authors.lastname: Moldovan
authors.forename: Poul
authors.initials: P
authors.lastname: Jennum
authors.forename: Martin
authors.initials: M
authors.lastname: Fabricius
authors.forename: Krisztina
authors.initials: K
authors.lastname: Benedek
authors.forename: Noémi
authors.initials: N
authors.lastname: Andersen
authors.forename: Helle
authors.initials: H
authors.lastname: Hjalgrim
authors.forename: Peter
authors.initials: P
authors.lastname: Wolf
mesh_terms: D000293:Adolescent; D000328:Adult; D000465:Algorithms; D003937:Diagnosis, Differential; D004569:Electroencephalography / Q000379:methods*; D004576:Electromyography / Q000379:methods; D004827:Epilepsy / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012640:Seizures / Q000175:diagnosis* / Q000503:physiopathology*; D014741:Video Recording / Q000379:methods*; D055815:Young Adult