title: Recent developments in biocatalysis beyond the laboratory.
abstract: Recent developments in biocatalysis, where implementation beyond the laboratory has been demonstrated, are explored: the use of transglutaminases to modify foods, reduce allergenicity and produce advanced materials, lipases for biodiesel production, and transaminases for biochemical production. The availability and application of enzymes at pilot and larger scale opens up possibilities for further improvements of biocatalyst-based processes and the development of new processes. Enzyme production, stability, activity, re-use, and product retrieval are common challenges for biocatalytic processes. We explore recent advances in biocatalysis within the process chain, such as protein engineering, enzyme expression, and biocatalyst immobilization, in the context of these challenges.
authors.affiliation: School of Biomolecular and Biomedical Science, Earth Institute UCD, University College Dublin, Belfield, Dublin 4, Ireland.
authors.forename: Tanja
authors.initials: T
authors.lastname: Narancic
authors.forename: Reeta
authors.initials: R
authors.lastname: Davis
authors.forename: Jasmina
authors.initials: J
authors.lastname: Nikodinovic-Runic
authors.forename: Kevin E
authors.initials: KE
authors.lastname: O' Connor
mesh_terms: D055162:Biocatalysis; D001709:Biotechnology / Q000379:methods* / Q000639:trends; D004800:Enzymes, Immobilized / Q000378:metabolism; D015870:Gene Expression; D015202:Protein Engineering
chemical_list: D004800:Enzymes, Immobilized