title: Hemophilus influenzae meningitis and septicaemia in a 14-month-old child after primary immunisation.
abstract: We report a 14-month-male child, who developed Hemophilus influenzae meningitis after three primary doses of the vaccine. The child presented with fever and seizures. H. influenzae was isolated from both cerebrospinal fluid (CSF) and blood. The child also had features of septicaemia. Procalcitonin (104 ng/ml) and C-reactive protein (CRP--42.6 mg/dl) were high. Appropriate antibiotics were given. The child made an uneventful recovery. This case highlights vaccine failure, especially after primary immunisation alone.
authors.affiliation: Department of Microbiology, Max Super Speciality Hospital, Saket, New Delhi, India.
authors.forename: B
authors.initials: B
authors.lastname: Tarai
authors.forename: N
authors.initials: N
authors.lastname: Ravishankar
authors.forename: P
authors.initials: P
authors.lastname: Vohra
authors.forename: P
authors.initials: P
authors.lastname: Das
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D006192:Haemophilus Infections / Q000175:diagnosis* / Q000473:pathology; D018073:Haemophilus Vaccines / Q000008:administration & dosage*; D006193:Haemophilus influenzae / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008297:Male; D016920:Meningitis, Bacterial / Q000175:diagnosis* / Q000473:pathology; D018805:Sepsis / Q000175:diagnosis* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D018073:Haemophilus Vaccines