title: Xanthones from the roots of Moutabea guianensis Aubl.
abstract: The phytochemical investigation of Moutabea guianensis roots led to the isolation of five polyoxygenated xanthones, including two new ones named moutabeone B (1,8-dihydroxy-4,5,6,7-tetramethoxyxanthone) and moutabeone C (1-hydroxy-4,5,6,7,8-pentamethoxyxanthone), along with the three known xanthones, 1,8-dihydroxy-4,6-dimethoxyxanthone, 1,8-dihydroxy-4,5,6-trimethoxyxanthone and augustin A (1,8-dihydroxy-4,6,7-trimethoxyxanthone). Structural characterization of all compounds was established on the basis of spectroscopic methods, mainly 1D and 2D nuclear magnetic resonance (NMR) and comparison with literature data. The antioxidant activity of compounds was tested through a thin layer chromatography (TLC) bioautography assay using 1,1-diphenyl-2-picryl-hydrazyl radical (DPPH·) as detection reagent. All tested compounds were more active (DL < 0.13-0.03 µg) than Trolox (DL < 0.15 µg), used as reference standard.
authors.affiliation: Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil. ripardofilho@ufpa.br.
authors.forename: Haroldo da S Ripardo
authors.initials: Hda S
authors.lastname: Filho
authors.affiliation: Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil. luidicp@hotmail.com.
authors.forename: Luidi C
authors.initials: LC
authors.lastname: Pacheco
authors.affiliation: Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil. edinaldometalurgico@hotmail.com.
authors.forename: Edinaldo da S
authors.initials: Eda S
authors.lastname: Andrade
authors.affiliation: Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil. majocost@ufpa.br.
authors.forename: Marivaldo José C
authors.initials: MJ
authors.lastname: Correa
authors.affiliation: Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil. raildamoreira@hotmail.com.
authors.forename: Railda Neyva M
authors.initials: RN
authors.lastname: Araújo
authors.affiliation: Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil. giselle@ufpa.br.
authors.forename: Giselle Maria S P
authors.initials: GM
authors.lastname: Guilhon
authors.affiliation: Programa de Pós-Graduação em Biotecnologia, Instituto de Ciências Biológicas, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil. joycekellys@ufpa.br.
authors.forename: Joyce Kelly R da
authors.initials: JK
authors.lastname: Silva
authors.affiliation: Instituto de Ciências Exatas e Naturais, Universidade Federal do Pará-UFPA, Rua Augusto Corrêa, S/N, 66075-900 Belém-PA, Brazil. lss@ufpa.br.
authors.forename: Lourivaldo S
authors.initials: LS
authors.lastname: Santos
mesh_terms: D002855:Chromatography, Thin Layer; D009682:Magnetic Resonance Spectroscopy; D018517:Plant Roots / Q000737:chemistry*; D029608:Polygalaceae / Q000737:chemistry*; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D044004:Xanthones