title: The effect of lavender essential oil on anxiety level in patients undergoing coronary artery bypass graft surgery: A double-blinded randomized clinical trial.
abstract: BACKGROUND
  Open heart surgery can cause high levels of anxiety in patients. Nowadays, lavender essential oil is widely used in medical research. This study was conducted with an aim to investigate the effects of lavender essential oil to reduce the anxiety of patients after coronary artery bypass surgery.
  
  
  METHODS
  This research is double-blinded randomized controlled trial on 60 patients who had undergone coronary artery bypass surgery in a 2-day intervention targeting reduction of anxiety. This study was conducted in Ekbatan Therapeutic and Educational Center, Hamadan city, Iran, in 2013. The patients in the inhalation aromatherapy group inhaled two drops of 2% lavender essential oil and those in the control group inhaled two drops of distilled water as placebo for 20 min on the 2(nd) and 3(rd) days after surgery. The level of anxiety was evaluated by Spielberger's State Anxiety questionnaire before and after intervention and the vital signs were documented as well. Data were analyzed using Stata 11 (Stata Corp., College Station, TX, USA) by independent t-test for continuous variables and Chi-square test for categorical variables.
  
  
  RESULTS
  The mean score of anxiety in the aromatherapy group was 48.73 ± 5.08 and in the control group was 48 ± 6.98 before the intervention (P = 0.64), which reduced after the intervention to 42.6 ± 5.44 and 42.73 ± 7.30, respectively. On the 3(rd) day after surgery, the mean score of anxiety in the aromatherapy group was 46.76 ± 4.07 and in the control group was 46.53 ± 7.05 before the intervention, which reduced to 41.33 ± 3.65 and 41.56 ± 6.18, respectively, after the intervention. However, there was no statistically significant difference in the mean scores of anxiety between the aromatherapy and control groups.
  
  
  CONCLUSIONS
  Lavender essential oil has no significant effect on anxiety in patients after coronary artery bypass surgery, although it decreased the level of anxiety in the patients.
authors.affiliation: Master of Science Critical Care Nursing, Larestan School of Medical Science, Larestan, Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Seifi
authors.affiliation: Chronic Diseases (Home Care) Research Center Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Beikmoradi
authors.affiliation: Mother and Child Care Research Center Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Khodayar
authors.initials: K
authors.lastname: Oshvandi
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Jalal
authors.initials: J
authors.lastname: Poorolajal
authors.affiliation: Department of Pharmacology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Malihe
authors.initials: M
authors.lastname: Araghchian
authors.affiliation: Department of Heart Surgery, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Safiaryan
keywords: Anxiety; Iran; aromatherapy; coronary artery bypass; plant medical