title: Blood transfusion practices in sepsis.
abstract: Sepsis is a clinical syndrome characterised by systemic inflammation due to infection. There is a spectrum with severity ranging from sepsis to severe sepsis and septic shock. Even with optimal treatment, mortality due to severe sepsis or septic shock is significant and poses a challenge to management. Antibiotics, source control, resuscitation with fluids, vasopressor and inotropic agents are the main-stay of treatment for septic shock. These may be supplemented with transfusion of red blood cells and or blood products, in the case of anaemia to sustain sufficient oxygen delivery([1]) or to manage associated haematological issues. Transfusion in sepsis has always been a debatable issue, especially in relation to choice of the fluid and the role of blood or blood product transfusion.
authors.affiliation: Department of Anesthesia and Crtical Care, Command Hospital, Armed Forces Medical College, Pune, Maharashtra, India.
authors.forename: Tvsp
authors.initials: T
authors.lastname: Murthy
keywords: Hypotension; intravenous fluids; red blood cell transfusion; sepsis