title: Engineering artificial machines from designable DNA materials for biomedical applications.
abstract: Deoxyribonucleic acid (DNA) emerges as building bricks for the fabrication of nanostructure with complete artificial architecture and geometry. The amazing ability of DNA in building two- and three-dimensional structures raises the possibility of developing smart nanomachines with versatile controllability for various applications. Here, we overviewed the recent progresses in engineering DNA machines for specific bioengineering and biomedical applications.
authors.affiliation: 1Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin, P.R. China.|2School of Chemical Engineering and Technology, Tianjin University, Tianjin, P.R. China.
authors.forename: Hao
authors.initials: H
authors.lastname: Qi
authors.affiliation: 3MOE Key Laboratory of Biomedical Information Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.|4Bioinspired Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, P.R. China.
authors.forename: Guoyou
authors.initials: G
authors.lastname: Huang
authors.affiliation: 3MOE Key Laboratory of Biomedical Information Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.|4Bioinspired Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, P.R. China.
authors.forename: Yulong
authors.initials: Y
authors.lastname: Han
authors.affiliation: 3MOE Key Laboratory of Biomedical Information Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.|4Bioinspired Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, P.R. China.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Zhang
authors.affiliation: 3MOE Key Laboratory of Biomedical Information Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.|4Bioinspired Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, P.R. China.
authors.forename: Yuhui
authors.initials: Y
authors.lastname: Li
authors.affiliation: 5Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Belinda
authors.initials: B
authors.lastname: Pingguan-Murphy
authors.affiliation: 4Bioinspired Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, P.R. China.
authors.forename: Tian Jian
authors.initials: TJ
authors.lastname: Lu
authors.affiliation: 3MOE Key Laboratory of Biomedical Information Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.|4Bioinspired Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, P.R. China.
authors.forename: Feng
authors.initials: F
authors.lastname: Xu
authors.affiliation: 3MOE Key Laboratory of Biomedical Information Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, P.R. China.|4Bioinspired Engineering and Biomechanics Center, Xi'an Jiaotong University, Xi'an, P.R. China.
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
mesh_terms: D000818:Animals; D057005:Bioengineering / Q000379:methods; D004247:DNA / Q000737:chemistry*; D006801:Humans; D049329:Nanostructures / Q000737:chemistry*; D009690:Nucleic Acid Conformation
chemical_list: D004247:DNA