title: [Intracranial and cerebral perfusion pressure in neurosurgical patients during anaesthesia with xenon].
abstract: Despite difficulties in providing xenon anaesthesia, xenon still seems to be attractive for neurosurgical procedures. But data upon its effect on intracranial (ICP) and cerebral perfusion pressure (CPP) remains controversial. We monitored ICP and CPP in patients with or without intracranial hypertension during xenon inhalation in different concentrations. Our results suggest that caution should be used while inhaling xenon in high anaesthetic concentration in patients wiith known intracranial hypertension. We also address new possibilities of xenon use, e.g., for sedation in neurosurgery. The study was supported by Russian Fund for Fundamental Research, grant number 13-04-01640.
authors.forename: A V
authors.initials: AV
authors.lastname: Rylova
authors.forename: A G
authors.initials: AG
authors.lastname: Gavrilov
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Lubnin
authors.forename: A A
authors.initials: AA
authors.lastname: Potapov
mesh_terms: D000328:Adult; D000368:Aged; D018685:Anesthetics, Inhalation / Q000008:administration & dosage / Q000009:adverse effects*; D001794:Blood Pressure / Q000187:drug effects; D001932:Brain Neoplasms / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D007427:Intracranial Pressure / Q000187:drug effects*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D019635:Neurosurgical Procedures / Q000379:methods*; D016896:Treatment Outcome; D014978:Xenon / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D018685:Anesthetics, Inhalation; D014978:Xenon