title: [Antimicrobial compounds of enterococci].
abstract: The main studies of a group of antimicrobial compounds produced by Enterococcus genus bacteria: bacteriocins, organic acids, activated oxygen metabolites, enzymes, exopolysaccharides--are described in the review. Data on synergic interaction of these substances in killing of pathogens, formation of active substances from different components as a result of metabolic activity of enterococci are presented. Production of these compounds is a reflection of competitive habitation of bacteria under the conditions of multi-species microbiomes and ensures colonization resistance of host biotopes. A complementation of the group of bacterial antimicrobial compounds by compounds that do not have a direct effect on the growth of microorganisms but suppress pathogenic potential of infectious disease causative agents is assumed.
authors.forename: A V
authors.initials: AV
authors.lastname: Valyshev
mesh_terms: D000890:Anti-Infective Agents / Q000378:metabolism*; D023181:Antimicrobial Cationic Peptides / Q000096:biosynthesis* / Q000378:metabolism / Q000627:therapeutic use; D001430:Bacteriocins / Q000378:metabolism / Q000627:therapeutic use; D018441:Biofilms / Q000187:drug effects / Q000254:growth & development; D003141:Communicable Diseases / Q000188:drug therapy* / Q000382:microbiology; D016983:Enterococcus / Q000378:metabolism*; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism
chemical_list: D000890:Anti-Infective Agents; D023181:Antimicrobial Cationic Peptides; D001430:Bacteriocins; D017382:Reactive Oxygen Species; D006861:Hydrogen Peroxide