title: [Independent lung ventilation for asymmetric injury: case report as a demonstration of common challenge].
abstract: The article deals with a case of conventional mechanical ventilation in 75 y.o. woman with the background of uncompensated diabetes mellitus, suffering from bilateral pneumonia with predominantly left-sided lesion and severe sepsis. The conventional mechanical ventilation with high pressure levels led to arterial hypoxemia with P/F ratio 52. Independent lung ventilation immediately increased oxygenation up to P/F ratio 225 and evidently improved left lung aeration. The case demonstrates that while applying high pressures to open alveoli, we could not only provoke ventilator-induced lung injury and low cardiac output, but also "squeeze out" pulmonary perfusion from ventilated areas to non-ventilated ones with less intraalveolar pressure levels.
authors.forename: K M
authors.initials: KM
authors.lastname: Lebedinskiĭ
authors.forename: D A
authors.initials: DA
authors.lastname: Artiukov
authors.forename: M V
authors.initials: MV
authors.lastname: Borisov
authors.forename: T A
authors.initials: TA
authors.lastname: Gromova
authors.forename: O A
authors.initials: OA
authors.lastname: Slivin
mesh_terms: D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D010100:Oxygen / Q000097:blood; D011014:Pneumonia / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D011175:Positive-Pressure Respiration / Q000379:methods*; D011659:Pulmonary Gas Exchange / Q000502:physiology; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D018805:Sepsis / Q000150:complications / Q000175:diagnosis / Q000628:therapy
chemical_list: D010100:Oxygen