title: A review of the benefits of Satureja species on metabolic syndrome and their possible mechanisms of action.
abstract: Metabolic syndrome, also known as insulin resistance disorder, is the simultaneous manifestation of multiple metabolic disorders in an individual. The present-day complementary and alternative therapies suggest several medicinal herbs that may have the potential to improve one or multiple complications of metabolic syndrome. All of them have their own limitations in efficacy and unwanted effects. Therefore, we reviewed species of Satureja as widespread medicinal herbs and potentially good remedies for metabolic syndrome. We reviewed literature found in PubMed and the ISI Web of Knowledge with the key word Satureja in the title. The influence of any species of Satureja on any disease or syndrome, enzymatic, metabolic, or physiological pathways, in human, animals, or in vitro conditions related to any characteristics of metabolic syndrome were considered. The main outcomes of treatment with Satureja species were categorized, and the possible mechanisms of action are discussed in this article.
authors.affiliation: Department of Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Siavash
authors.initials: S
authors.lastname: Babajafari
authors.affiliation: Student Research Committee, Research Office for the History of Persian Medicine, Shiraz University of Medical Sciences, Shiraz, Iran nikaeinf@sums.ac.ir.
authors.forename: Farzad
authors.initials: F
authors.lastname: Nikaein
authors.affiliation: Department of Food Hygiene and Quality Control, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Seyed Mohammad
authors.initials: SM
authors.lastname: Mazloomi
authors.affiliation: Department of Cardiology, Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mohammad Javad
authors.initials: MJ
authors.lastname: Zibaeenejad
authors.affiliation: Pharmaceutical Sciences Research Center & Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Arman
authors.initials: A
authors.lastname: Zargaran
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D002460:Cell Line; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents; D000960:Hypolipidemic Agents; D008297:Male; D024821:Metabolic Syndrome; D010936:Plant Extracts; D051381:Rats; D031362:Satureja
chemical_list: D000893:Anti-Inflammatory Agents; D000975:Antioxidants; D007004:Hypoglycemic Agents; D000960:Hypolipidemic Agents; D010936:Plant Extracts
keywords: Satureja; medicinal herb; metabolic syndrome