title: Maxillary Sinus Augmentation with a New Xenograft: A Randomized Controlled Clinical Trial.
abstract: BACKGROUND
  Insufficient residual alveolar bone height is a common deterrent in the placement of dental implants in the posterior maxilla. The use of autografts, xenografts, allografts and alloplasts or a combination between them has been demonstrated to be effective for increasing bone height and bone volume in the deficient posterior maxilla.
  
  
  OBJECTIVE
  The aim of this clinical trial is to comparatively determine the density of newly formed in sinus floor augmentation bone after a 24-week healing period treatment with a new bovine xenograft.
  
  
  METHODS
  The sinus floor was grafted with Bio-Oss® (n = 10) and Osseous® (n = 10). Histological sections were examined with a focus on the presence of connective tissue (CT) and newly formed bone (NFB). The sections were histomorphometrically evaluated and the definitive crown was inserted after 3 months.
  
  
  RESULTS
  After 6 months, the mean value of new bone formation was 24.60 (±2.503), the CT was 42.60 (±4.006) and the remaining biomaterial was 25.40 (±2.547) in Bio-Oss group. In Osseous group, the mean value of new bone formation was 24.90 (±3.542), the CT was 45.70 (±7.040) and the remaining biomaterial was 22.90 (±3.247).
  
  
  CONCLUSIONS
  Both biomaterials afforded a favorable implant position and the prosthetic rehabilitation.
authors.affiliation: Dental Clinical Research Center, Oral Surgery Department, Dentistry School, Fluminense Federal University, Niteroi, RJ, Brazil.
authors.forename: Mônica Diuana
authors.initials: MD
authors.lastname: Calasans-Maia
authors.affiliation: Dentistry School, Fluminense Federal University, Niteroi, RJ, Brazil.
authors.forename: Carlos Fernando de A B
authors.initials: CF
authors.lastname: Mourão
authors.affiliation: Dentistry School, Fluminense Federal University, Niteroi, RJ, Brazil.
authors.forename: Adriana Terezinha Neves Novellino
authors.initials: AT
authors.lastname: Alves
authors.affiliation: Dentistry School, Fluminense Federal University, Niteroi, RJ, Brazil.
authors.forename: Suelen Cristina
authors.initials: SC
authors.lastname: Sartoretto
authors.affiliation: Dentistry School, Fluminense Federal University, Niteroi, RJ, Brazil.
authors.forename: Marcelo José P G
authors.initials: MJ
authors.lastname: de Uzeda
authors.affiliation: Dentistry School, Fluminense Federal University, Niteroi, RJ, Brazil.|Bioengineering Program, National Institute of Metrology, Quality and Technology, Duque de Caxias, RJ, Brazil.
authors.forename: José Mauro
authors.initials: JM
authors.lastname: Granjeiro
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D018786:Bone Substitutes / Q000627:therapeutic use*; D002417:Cattle; D003758:Dental Implantation, Endosseous / Q000379:methods; D005260:Female; D064593:Heterografts / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D008903:Minerals / Q000627:therapeutic use*; D059546:Sinus Floor Augmentation / Q000379:methods*
chemical_list: C077540:Bio-Oss; D018786:Bone Substitutes; D008903:Minerals
keywords: atrophic maxilla; bone augmentation; sinus floor elevation; xenograft