title: [A case of cerebellar hemangioblastoma complicated by pregnancy and concerns about the surgical period].
abstract: We report herein a case of cerebellar hemangioblastoma complicated by pregnancy and concerns about the period in which surgery could be performed successfully. A 19-year-old woman, who was also 35 weeks pregnant, was admitted to our hospital with headache, nausea, and general fatigue. Neurological examination on admission revealed disturbed consciousness, and the patient's general condition was poor. Computed tomography and magnetic resonance imaging showed a large tumor in the cerebellar vermis along with an obstructive hydrocephalus. Computed tomographic angiography with three-dimensional reconstruction revealed feeding arteries and a draining vein in this tumor. Based on the clinical features, hemangioblastoma was suspected, and surgical excision and extraction of the fetus were scheduled. However, because of rapid neurological deterioration due to tumor progression, an emergency cesarean section was performed under general anesthesia. After extracting the fetus, the level of consciousness improved, so a tumor resection was planned after the patient's general condition improved. However, the neurological state deteriorated again due to the worsening hydrocephalus, which was suspected to be caused by the increased cerebral blood flow following uterine contraction. Emergency surgery for the brain tumor was performed two days after delivery. The tumor was resected completely and histopathological examination confirmed a diagnosis of hemangioblastoma. The postoperative course was uneventful, and the patient and newborn were discharged with no neurological deficits three weeks after the operation. This case suggested that if we encounter patients with brain tumors complicated by pregnancy, not only is earlier diagnosis from clinical features important, but also persistent additional treatment should be carried out without delay to effectively control intracranial pressure.
authors.affiliation: Department of Neurosurgery, Ehime University School of Medicine.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Inoue
authors.forename: Shohei
authors.initials: S
authors.lastname: Kohno
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kumon
authors.forename: Hideaki
authors.initials: H
authors.lastname: Watanabe
authors.forename: Takanori
authors.initials: T
authors.lastname: Ohnishi
authors.forename: Hisashi
authors.initials: H
authors.lastname: Hashimoto
authors.forename: Keiichi
authors.initials: K
authors.lastname: Matsubara
mesh_terms: D000328:Adult; D002528:Cerebellar Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006261:Headache / Q000175:diagnosis / Q000473:pathology; D018325:Hemangioblastoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D008279:Magnetic Resonance Imaging / Q000379:methods; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000601:surgery*