title: [Yeast species in vulvovaginitis candidosa].
abstract: BACKGROUND
  Vulvovaginal candidiasis is the most common mycosis, however, the available information about antifungal susceptibilities of these yeasts is limited.
  
  
  OBJECTIVE
  To compare the gold standard fungal culture with a new molecular identification method and report the incidence of yeast species in vulvovaginitis candidosa.
  
  
  METHODS
  The authors studied 370 yeasts isolated from vulvovaginal candidiasis and identified them by phenotypic and molecular methods.
  
  
  RESULTS
  The most common species was Candida albicans (85%), followed by Candida glabrata, and other Candida species.
  
  
  CONCLUSIONS
  At present there are no recommendations for the evaluation of antifungal susceptibility of pathogenic fungal species occurring in vulvovaginal candidiasis and the natural antifungal resistance of the different species is known only. Matrix Assisted Laser Desorption Ionization Time of Flight identification can be used to differentiate the fluconazole resistant Candida dubliniensis and the sensitive Candida albicans strains.
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
authors.forename: Éva
authors.initials: É
authors.lastname: Nemes-Nikodém
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
authors.forename: Béla
authors.initials: B
authors.lastname: Tamási
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
authors.forename: Noémi
authors.initials: N
authors.lastname: Mihalik
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085.
authors.forename: Eszter
authors.initials: E
authors.lastname: Ostorházi
mesh_terms: D000282:Administration, Intravaginal; D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002175:Candida / Q000302:isolation & purification*; D002176:Candida albicans / Q000302:isolation & purification; D041221:Candida glabrata / Q000302:isolation & purification; D041022:Candida tropicalis / Q000302:isolation & purification; D002181:Candidiasis, Vulvovaginal / Q000175:diagnosis* / Q000188:drug therapy*; D003276:Contraceptives, Oral / Q000008:administration & dosage / Q000009:adverse effects; D048909:Diabetes Complications / Q000382:microbiology; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D006814:Hungary; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D003276:Contraceptives, Oral; D015725:Fluconazole
keywords: Matrix Assisted Laser Desorption Ionization Time of Flight identification method; Matrix Assisted Laser Desorption Ionization Time of Flight identifikálási módszer; fluconazole resistant Candida dubliniensis; flukonazolrezisztens Candida dubliniensis; vulvovaginitis candidiosa