title: Osseointegrated implant-based dental rehabilitation in head and neck reconstruction patients.
abstract: Dental restoration is an integral part of head and neck cancer reconstruction.
  
  
  
  We evaluated the success rate of osseointegrated implants in patients with head and neck cancer, comparing outcomes between implants placed in fibula free flaps to those placed in native mandibular and maxillary bone.
  
  
  
  A total of 1132 implants were placed in 246 patients. The overall implant loss rate was 3.7% and was higher in fibula flaps (8.2%) compared to the native mandible (2.6%) and maxilla (2.2%), although these differences did not reach statistical significance (p = .059 and p = .053, respectively). The failure rate was 8.0% for implants placed after radiation and 3.6% in patients who did not undergo radiation (p = .097). Osteoradionecrosis (ORN) occurred in 19 patients (7.7%) after implant placement, and tobacco use was found to be a risk factor (p = .027).
  
  
  
  Osseointegrated implants are reliable in patients with head and neck cancer, including those undergoing bony free flap reconstruction. © 2015 Wiley Periodicals, Inc. Head Neck 38: E321-E327, 2016.
authors.affiliation: Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.|Department of Plastic Surgery, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.|The Institute of Academic Surgery, University of Sydney, New South Wales, Australia.
authors.forename: Sydney
authors.initials: S
authors.lastname: Ch'ng
authors.affiliation: Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
authors.forename: Roman J
authors.initials: RJ
authors.lastname: Skoracki
authors.affiliation: Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
authors.forename: Jesse C
authors.initials: JC
authors.lastname: Selber
authors.affiliation: Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
authors.forename: Peirong
authors.initials: P
authors.lastname: Yu
authors.affiliation: Dental Oncology Section, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
authors.forename: Jack W
authors.initials: JW
authors.lastname: Martin
authors.affiliation: Dental Oncology Section, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
authors.forename: Theresa M
authors.initials: TM
authors.lastname: Hofstede
authors.affiliation: Dental Oncology Section, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
authors.forename: Mark S
authors.initials: MS
authors.lastname: Chambers
authors.affiliation: Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
authors.forename: Matthew M
authors.initials: MM
authors.lastname: Hanasono
mesh_terms: D016025:Bone Transplantation; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D005260:Female; D005360:Fibula; D058752:Free Tissue Flaps; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D008334:Mandible; D008437:Maxilla; D008875:Middle Aged; D016348:Osseointegration; D019651:Plastic Surgery Procedures
chemical_list: D015921:Dental Implants
keywords: fibula free flap; head and neck cancer; microvascular free flaps; osseointegrated implants; prosthodontics