title: RNA sequencing reveals a unique fusion of the lysine (K)-specific methyltransferase 2A and smooth muscle myosin heavy chain 11 in myelodysplastic syndrome and acute myeloid leukemia.
authors.affiliation: Department of Hematology and Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.
authors.forename: Mathijs A
authors.initials: MA
authors.lastname: Sanders
authors.affiliation: Department of Hematology and Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.
authors.forename: François G
authors.initials: FG
authors.lastname: Kavelaars
authors.affiliation: Department of Hematology and Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.
authors.forename: Annelieke
authors.initials: A
authors.lastname: Zeilemaker
authors.affiliation: Department of Hematology and Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.
authors.forename: Adil S A
authors.initials: AS
authors.lastname: Al Hinai
authors.affiliation: Department of Hematology and Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.
authors.forename: Saman
authors.initials: S
authors.lastname: Abbas
authors.affiliation: Department of Hematology and Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.
authors.forename: H Berna
authors.initials: HB
authors.lastname: Beverloo
authors.affiliation: Department of Hematology and Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands.
authors.forename: Kirsten
authors.initials: K
authors.lastname: van Lom
authors.affiliation: Department of Hematology and Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands p.valk@erasmusmc.nl.
authors.forename: Peter J M
authors.initials: PJ
authors.lastname: Valk
mesh_terms: D000368:Aged; D005500:Follow-Up Studies; D050939:Gene Fusion; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D011495:Histone-Lysine N-Methyltransferase / Q000235:genetics*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D009190:Myelodysplastic Syndromes / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D051788:Myeloid-Lymphoid Leukemia Protein / Q000235:genetics*; D018995:Myosin Heavy Chains / Q000235:genetics*; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D011379:Prognosis; D017423:Sequence Analysis, RNA / Q000379:methods
chemical_list: C497422:KMT2A protein, human; C509903:MYH11 protein, human; D015514:Oncogene Proteins, Fusion; D051788:Myeloid-Lymphoid Leukemia Protein; D011495:Histone-Lysine N-Methyltransferase; D018995:Myosin Heavy Chains
keywords: KMT2A; MYH11; acute myeloid leukemia; mutations; myelodysplastic syndrome