title: One-step synthesis of amine-functionalized hollow mesoporous silica nanoparticles as efficient antibacterial and anticancer materials.
abstract: In this study, amine-functionalized hollow mesoporous silica nanoparticles with an average diameter of ∼100 nm and shell thickness of ∼20 nm were prepared by an one-step process. This new nanoparticulate system exhibited excellent killing efficiency against mycobacterial (M. smegmatis strain mc(2) 651) and cancer cells (A549).
authors.affiliation: Department of Chemistry, University of Massachusetts , Lowell, Massachusetts 01854, United States.
authors.forename: Nanjing
authors.initials: N
authors.lastname: Hao
authors.forename: Kalana W
authors.initials: KW
authors.lastname: Jayawardana
authors.forename: Xuan
authors.initials: X
authors.lastname: Chen
authors.forename: Mingdi
authors.initials: M
authors.lastname: Yan
mesh_terms: D000588:Amines / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004317:Doxorubicin / Q000737:chemistry / Q000494:pharmacology; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry*; D016503:Drug Delivery Systems / Q000295:instrumentation*; D006801:Humans; D020102:Mycobacterium smegmatis / Q000187:drug effects; D053758:Nanoparticles / Q000737:chemistry*; D016062:Porosity; D012822:Silicon Dioxide / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000588:Amines; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D004337:Drug Carriers; D012822:Silicon Dioxide; D004317:Doxorubicin
keywords: amine-functionalized; antibacterial; anticancer; drug delivery; hollow mesoporous silica nanoparticles