title: Tracking the evolution of drug abuse in China, 2003-10: a retrospective, self-controlled study.
abstract: OBJECTIVE
  To characterize trends in drug abuse in China before and after the 2005 initiation of the 'People's War on Drugs'.
  
  
  METHODS
  Retrospective self-controlled study.
  
  
  METHODS
  Annual, nation-wide surveillance from 2003 to 2010 of all registered drug users in China's National Surveillance System on Drug Abuse (NSSDA).
  
  
  METHODS
  A total of 1,184,124 drug users registered in NSSDA were involved in this study and were classified into three groups based on registered dates-pre-war group (n=230,278) registered 2003-04, phase I group (n=518,651) registered 2005-07 and phase II group (n=435,195) registered 2008-10.
  
  
  METHODS
  Indicators included proportions of:(i) new and relapsed drug users, (ii) heroin and synthetic drug users among new users, (iii) people aged 35 years or younger and (iv) women. Comparisons were made across groups using annual data to describe temporal trends.
  
  
  RESULTS
  Between 2003 and 2010 the proportion of heroin users decreased by 52.3% and synthetic drugs use increased 860.7% among new users, while a 12.8% decrease in the proportion of heroin users and a 918.8% increase in synthetic drug use in all users was detected. Compared with the pre-war group, the proportion of relapsed users decreased 2.6% and 29.1% in the phase I and phase II groups, respectively, but a significant increase in the proportion of new users was found in phase I (OR=1.24, CI=1.15-1.35, p<0.0001), followed by an apparent decrease in phase II compared with phase I (OR=0.75, CI=0.70-0.80, p<0.0001). Similarly, the proportion of heroin users decreased 15.1 and 24.2% among new drug users in phase I and phase II in comparison with the pre-war group.
  
  
  CONCLUSIONS
  The decrease in proportions of drug users in China between 2003/4 and 2008/10 may suggest some positive influence of the 'People's War on Drugs', especially in the decreased proportion of relapsed users. In contrast, there was a rapid increase in new synthetic drug use over the same period.
authors.affiliation: National Institute on Drug Dependence, Peking University, Beijing, China; Takemi Program in International Health, Department of Global Health and Population, Harvard School of Public Health, Boston, MA, USA.
authors.forename: Zhongwei
authors.initials: Z
authors.lastname: Jia
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Liu
authors.forename: Ping
authors.initials: P
authors.lastname: Chu
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: McGoogan
authors.forename: Minchao
authors.initials: M
authors.lastname: Cong
authors.forename: Jie
authors.initials: J
authors.lastname: Shi
authors.forename: Lin
authors.initials: L
authors.lastname: Lu
mesh_terms: D000328:Adult; D002681:China / Q000453:epidemiology; D055030:Drug Users / Q000706:statistics & numerical data*; D058872:Epidemics / Q000517:prevention & control*; D062665:Epidemiological Monitoring; D005260:Female; D003932:Heroin / Q000009:adverse effects*; D006556:Heroin Dependence / Q000453:epidemiology*; D006801:Humans; D008297:Male; D012008:Recurrence; D012189:Retrospective Studies; D057566:Self Report
chemical_list: D003932:Heroin
keywords: China; drug user; heroin; relapse; synthetic drugs