title: [The clinical comparison of conjunctival resection with conjunctival resection and sclera fixation in the treatment of conjunctivochalasis].
abstract: OBJECTIVE
  To evaluate the efficacy of two surgical treatments for conjunctivochalasis.
  
  
  METHODS
  Prospective randomized control study. Thirty-three conjunctivochalasis patients (33 eyes) were randomly divided into two groups:simple resection group, and resection and fixation group. The former received simple conjunctival resection, and the latter received conjunctival resection and scleral fixation. Postoperative conjunctiva relaxation, BUT and ocular surface disease index (OSDI) points were compared to evaluate the efficacy of the two kinds of surgical methods.
  
  
  RESULTS
  The recurrence rate of conjunctivochalasis was 6/16 in the simple resection group and 1/17 in the resection and fixation group on month 6 after operation, and there was significant difference (P = 0.039). In 1 month, 3 months and 6 months postoperatively, the proportion of normal BUT increased respectively in both groups (simple resection group:8/16, 9/16, 10/16; resection and fixation group:8/17, 10/17, 11/17) compared with that before operation (simple resection group:3/16; resection and fixation group:4/17). The difference was statistically significant 6 months after operation compared with that before operation (simple resection group:P = 0.029; resection and fixation group:P = 0.037), but there was no statistical significance between the two groups at each time point postoperatively (P = 1.00). OSDI scores were significantly decreased in 6 months after operation in both groups (simple resection group:7.76 ± 2.42; resection and fixation group:7.21 ± 2.39) compared with those before operation (simple resection group:22.35 ± 14.68; resection and fixation group:21.83 ± 15.73). Both of the differences were statistically significant (simple resection group:t = 6.598, P < 0.01; resection and fixation group:t = 6.603, P < 0.01), but there was no statistically significant difference between the two groups on month 6 postoperatively (t = 0.647, P = 0.537).
  
  
  CONCLUSIONS
  Both conjunctival resection and conjunctival resection with sclera fixation can effectively improve symptoms, but the latter has a lower recurrence rate.
authors.affiliation: Clinical College of Opthalmology, Tianjin Medical University, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin 300020, China.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Wang
authors.affiliation: Clinical College of Opthalmology, Tianjin Medical University, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin 300020, China.
authors.forename: Fengju
authors.initials: F
authors.lastname: Chen
authors.affiliation: Clinical College of Opthalmology, Tianjin Medical University, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin 300020, China. Email: tangprofessor@yahoo.com.cn.
authors.forename: Xin
authors.initials: X
authors.lastname: Tang
mesh_terms: D000368:Aged; D003228:Conjunctiva / Q000601:surgery*; D003229:Conjunctival Diseases / Q000601:surgery*; D006801:Humans; D013508:Ophthalmologic Surgical Procedures / Q000379:methods; D011184:Postoperative Period; D011446:Prospective Studies; D012008:Recurrence; D012590:Sclera / Q000601:surgery*; D016896:Treatment Outcome