title: [Presymptomatic genetic testing in minors should only be performed when intervention is possible].
abstract: Presymptomatic genetic testing in minors is subject to debate. We reviewed guidelines on the subject from four large medical genetics societies. A general consensus exists regarding presymptomatic testing with the main justification for such testing being the direct benefit to the child through medical intervention or preventive measures. The child's best interest is central, but there is disagreement as to whether psychosocial and familial aspects should be included in this concept. Empirical evidence is lacking. We recommend increased awareness regarding the complexity of this issue.
authors.affiliation: Klinisk Genetisk Klinik, Kennedy -Centret, Gamle Landevej 7, 2600 Glostrup. jannebayerandersen@gmail.com.
authors.forename: Janne Bayer
authors.initials: JB
authors.lastname: Andersen
authors.forename: Birgitte Rode
authors.initials: BR
authors.lastname: Diness
authors.forename: Karen
authors.initials: K
authors.lastname: Brøndum-Nielsen
mesh_terms: D002648:Child; D005817:Genetic Counseling; D030342:Genetic Diseases, Inborn / Q000175:diagnosis; D005820:Genetic Testing / Q000941:ethics / Q000592:standards; D006801:Humans; D033242:Minors / Q000523:psychology; D017410:Practice Guidelines as Topic; D012955:Societies, Medical