title: Comparison of the Relative Renal Function Calculated with 99mTc-Diethylenetriaminepentaacetic Acid and 99mTc-Dimercaptosuccinic Acid in Children.
abstract: The aim was to compare the relative renal functions measured with technetium-99m dimercaptosuccinic acid (99mTc-DMSA) and technetium-99m diethylenetriaminepentaacetic acid (99mTc-DTPA) in children with renal diseases. Relative renal function of 128 children who applied to three hospitals from 2009 to 2011 were analyzed retrospectively. The mean value measured with 99mTc-DTPA and 99mTc-DMSA were 51.58 ± 14.95 and 51.96 ± 14.99 for the right kidney, 47.87 ± 15.27 and 47.94 ± 15.17 for the left kidney, respectively. A significant positive correlation was found between the relative renal functions (r = 0.963, P < 0.001). In Bland-Altman plots, the mean difference between two methods was 0.7 and the correlation limits were between 10.1 and-10.8. As a result, although 99mTc-DMSA is accepted as the most reliable method for the determination of relative renal function, 99mTc-DTPA can be another choice for the calculation of relative renal function without a complementary DMSA scan particularly in pediatric patients who require renogram curve and GFR calculations.
authors.affiliation: Department of Pediatrics, School of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey.
authors.forename: Tanju
authors.initials: T
authors.lastname: Çelik
authors.affiliation: Department of Nuclear Medicine, School of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey.
authors.forename: Hülya
authors.initials: H
authors.lastname: Yalçin
authors.affiliation: Department of Nuclear Medicine, School of Medicine, Mersin University, Mersin, Turkey.
authors.forename: Emel Ceylan
authors.initials: EC
authors.lastname: Günay
authors.affiliation: Department of Nuclear Medicine, Bağcılar Hospital, İstanbul, Turkey.
authors.forename: Aynur
authors.initials: A
authors.lastname: Özen
authors.affiliation: Department of Family Medicine, School of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey.
authors.forename: Cahit
authors.initials: C
authors.lastname: Özer
keywords: Child; relative renal function; technetium-99m diethylenetriaminepentaacetic acid; technetium-99m dimercaptosuccinic acid