title: Determination triazine pesticides in cereal samples based on single-hole hollow molecularly imprinted microspheres.
abstract: Single-hole hollow molecularly imprinted microspheres (h-MIMs) were prepared by hard template method and applied to extract six triazine pesticides in cereal samples, followed by HPLC-MS/MS detection. The synthesis mechanism of the h-MIMs has been studied. The h-MIMs exhibited bigger specific surface area and much higher binding capacity than the molecularly imprinted polymers prepared by precipitation polymerization (p-MIPs) and surface polymerization (s-MIPs). Besides, the adsorption rate of h-MIMs to prometryn was significantly higher than that of p-MIPs and s-MIPs. Owing to the hollow structure of the h-MIMs, more binding cavities were located on the inner and outer surfaces of the h-MIMs, which could facilitate the removal of template molecules from the polymers and the rebinding of the target molecules to the polymers. Under the optimal conditions, the detection limits of triazines are in the range of 0.08-0.16ngg(-1). At the spiked level (5ngg(-1)), the recoveries of triazines are in the range of 81±4% to 96±4%. The proposed method was successfully applied to determine six triazines in five cereal samples. Atrazine was found in two rice samples and a wheat sample with the contents of 5.1, 6.7 and 5.6ngg(-1), respectively. Ametryn and prometryn were found in a maize sample with the contents of 7.6 and 7.3ngg(-1), respectively.
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhao
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Huiyu
authors.initials: H
authors.lastname: Li
authors.affiliation: College of Life Sciences, Jilin University, Changchun 130012, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Xu
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Fengshuang
authors.initials: F
authors.lastname: Zhang
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Jiahui
authors.initials: J
authors.lastname: Zhao
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Long
authors.initials: L
authors.lastname: Wang
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Hou
authors.affiliation: State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Ding
authors.affiliation: State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Li
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Jin
authors.affiliation: College of Chemistry, Jilin University, 2699 Qianjin Street, Changchun 130012, China. Electronic address: dinglan@jlu.edu.cn.
authors.forename: Lan
authors.initials: L
authors.lastname: Ding
mesh_terms: D000327:Adsorption; D002851:Chromatography, High Pressure Liquid; D003432:Cross-Linking Reagents / Q000737:chemistry; D002523:Edible Grain / Q000737:chemistry*; D008863:Microspheres; D054802:Molecular Imprinting; D012275:Oryza / Q000737:chemistry; D010575:Pesticides / Q000032:analysis*; D058105:Polymerization; D019904:Polymethyl Methacrylate / Q000737:chemistry; D011400:Prometryne / Q000737:chemistry; D053719:Tandem Mass Spectrometry; D014227:Triazines / Q000032:analysis*; D014908:Triticum / Q000737:chemistry; D014753:Vinyl Compounds / Q000737:chemistry; D003313:Zea mays / Q000737:chemistry
chemical_list: D003432:Cross-Linking Reagents; D010575:Pesticides; D014227:Triazines; D014753:Vinyl Compounds; D011400:Prometryne; D019904:Polymethyl Methacrylate; C004985:divinyl benzene
keywords: Cereal samples; Hollow molecularly imprinted microspheres; Liquid chromatography-tandem mass spectrometry; Single-hole polymers; Solid phase extraction; Triazine herbicides