title: Flavonoids from Symplocos racemosa.
abstract: A novel isoflavone glycoside, peseudobatigenin 7-O-[β-d-apiofuranosyl-(1''''→5''')-O-β-d-apiofuranosyl-(1'''→6'')]-β-d-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2-16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC50 value of 88.2, 42.1 and 74.3 μM, respectively.
authors.affiliation: College of Pharmacy, The Catholic University of Korea, Bucheon 420-743, Korea. jml333@nate.com.
authors.forename: Mila
authors.initials: M
authors.lastname: Jung
authors.affiliation: College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, Korea. dashutiao@naver.com.
authors.forename: Janggyoo
authors.initials: J
authors.lastname: Choi
authors.affiliation: College of Pharmacy and RFIND-BKplus Team, Dongguk University-Seoul, 32 Dongguk-lo, Ilsan dong-gu, Goyang, Gyeonggi-do 410-820, Korea. chaeheesung83@gmail.com.
authors.forename: Hee-Sung
authors.initials: HS
authors.lastname: Chae
authors.affiliation: Department of Genetic Engineering, Sungkyunkwan University, Suwon 440-746, Korea. jaecho@skku.edu.
authors.forename: Jae Youl
authors.initials: JY
authors.lastname: Cho
authors.affiliation: Department of Life Science, Hallym University, Chuncheon 200-702, Korea. ydkim@hallym.ac.kr.
authors.forename: Young-Dong
authors.initials: YD
authors.lastname: Kim
authors.affiliation: Popa Mountain Park, Forest Department, Kyaukpadaung Township, Mandalay Division, Myanmar. khinmyohtwe007@gmail.com.
authors.forename: Khin Myo
authors.initials: KM
authors.lastname: Htwe
authors.affiliation: Department of Forest Sciences, Seoul National University, Seoul 151-921, Korea. krane@snu.ac.kr.
authors.forename: Woo-Shin
authors.initials: WS
authors.lastname: Lee
authors.affiliation: College of Pharmacy and RFIND-BKplus Team, Dongguk University-Seoul, 32 Dongguk-lo, Ilsan dong-gu, Goyang, Gyeonggi-do 410-820, Korea. f2744@dongguk.edu.
authors.forename: Young-Won
authors.initials: YW
authors.lastname: Chin
authors.affiliation: College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, Korea. jwkim@snu.ac.kr.
authors.forename: Jinwoong
authors.initials: J
authors.lastname: Kim
authors.affiliation: College of Pharmacy, The Catholic University of Korea, Bucheon 420-743, Korea. kdyoon@catholic.ac.kr.
authors.forename: Kee Dong
authors.initials: KD
authors.lastname: Yoon
mesh_terms: D000818:Animals; D002460:Cell Line; D002851:Chromatography, High Pressure Liquid; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D019684:Magnoliopsida / Q000737:chemistry*; D051379:Mice; D015394:Molecular Structure; D013057:Spectrum Analysis / Q000379:methods*
chemical_list: D005419:Flavonoids