title: Paediatric rheumatology in 2014: Digging deeper for greater precision and more impact in JIA.
abstract: Optimizing the management of childhood arthritis requires detailed knowledge of the disease in an individual patient. Advances in 2014 show how in-depth genetic studies and insights into immunopathogenesis could translate into clinical biomarkers and, eventually, individualized therapy.
authors.affiliation: Department of Paediatric Immunology &Laboratory for Translational Immunology, University Medical Centre Utrecht, PO Box 85090, 3508 AB Utrecht, Netherlands.
authors.forename: Berent
authors.initials: B
authors.lastname: Prakken
authors.affiliation: Department of Paediatrics, University of Genova, IRCCS G. Gaslini, Largo G. Gaslini 5, 16147 Genova, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Martini
mesh_terms: D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000235:genetics / Q000628:therapy*; D002648:Child; D006801:Humans; D042845:Laccase / Q000235:genetics; D057285:Precision Medicine; D012219:Rheumatology / Q000639:trends*
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D042845:Laccase; C502936:tocilizumab