title: Morita-Baylis-Hillman reaction of acrylamide with isatin derivatives.
abstract: The Morita-Baylis-Hillman reaction of acrylamide, as an activated alkene, has seen little development due to its low reactivity. We have developed the reaction using isatin derivatives with acrylamide, DABCO as a promoter and phenol as an additive in acetonitrile. The corresponding aza version with acrylate and acrylonitrile has also been developed resulting in high product yields.
authors.affiliation: Department of Chemistry, Faculty of Science, Banaras Hindu University, Varanasi-221005, India.
authors.forename: Radhey Mohan
authors.initials: RM
authors.lastname: Singh
authors.affiliation: Department of Chemistry, Faculty of Science, Banaras Hindu University, Varanasi-221005, India.
authors.forename: Kishor Chandra
authors.initials: KC
authors.lastname: Bharadwaj
authors.affiliation: Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Tarnaka, Hyderabad-500007, India.
authors.forename: Dharmendra Kumar
authors.initials: DK
authors.lastname: Tiwari
keywords: Morita–Baylis–Hillman; acrylamide; isatin; ketimine; phenol