title: Dechlorane Plus in paired hair and serum samples from e-waste workers: correlation and differences.
abstract: Dechlorane Plus (DP) and a dechlorinated product of DP were measured in 34 matched human hair and serum samples (19 males and 15 females) collected from e-waste recycling workers in South China. The DP (sum of syn- and anti-DP) concentrations in hair and serum samples ranged from 6.3 to 1100 ng g(-1) dry weight and from 22 to 1400 ng g(-1) lipid weight (lw). The levels of anti-Cl11-DP ranged from 0.02 to 1.8 ng g(-1) in hair and from not detected to 7.9 ng g(-1) lw in serum. Significant positive correlations for both DP and anti-Cl11-DP concentrations between hair and serum samples were found (p<0.05), indicating hair to be a suitable matrix for human DP exposure. However, a significant difference was found in the DP isomer composition between hair and serum, suggesting stereoselective bioaccumulation during the absorption of DP into hair. A sharp gender difference was found in the levels of DP in hair. Moreover, syn-DP, anti-DP and anti-Cl11-DP in hair significantly correlated with those in serum for male samples, but not for female samples. The observed gender differences in the present study may be, in part, ascribed to the much longer hair exposure time for females than males due to the difference in sampling distance from the scalp.
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China; University of the Chinese Academy of Sciences, Beijing 100049, China.
authors.forename: Kehui
authors.initials: K
authors.lastname: Chen
authors.affiliation: Center for Environmental Health Research, South China Institute of Environmental Sciences, Ministry of Environmental Protection, Guangzhou 510655, China; State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China. Electronic address: zhengjing@scies.org.
authors.forename: Jing
authors.initials: J
authors.lastname: Zheng
authors.affiliation: State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Yan
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China; Center for Environmental Health Research, South China Institute of Environmental Sciences, Ministry of Environmental Protection, Guangzhou 510655, China.
authors.forename: Lehuan
authors.initials: L
authors.lastname: Yu
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China. Electronic address: luoxiaoj@gig.ac.cn.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Luo
authors.affiliation: Center for Environmental Health Research, South China Institute of Environmental Sciences, Ministry of Environmental Protection, Guangzhou 510655, China.
authors.forename: Xiaowu
authors.initials: X
authors.lastname: Peng
authors.affiliation: Center for Environmental Health Research, South China Institute of Environmental Sciences, Ministry of Environmental Protection, Guangzhou 510655, China.
authors.forename: Yunjiang
authors.initials: Y
authors.lastname: Yu
authors.affiliation: State Key Laboratory for Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China.
authors.forename: Zhongyi
authors.initials: Z
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China.
authors.forename: Bixian
authors.initials: B
authors.lastname: Mai
mesh_terms: D002681:China; D059029:Electronic Waste; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D005260:Female; D005411:Flame Retardants / Q000032:analysis / Q000378:metabolism*; D006197:Hair / Q000737:chemistry*; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D008297:Male; D016273:Occupational Exposure; D011083:Polycyclic Compounds / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D059027:Recycling
chemical_list: D004785:Environmental Pollutants; D005411:Flame Retardants; D006843:Hydrocarbons, Chlorinated; D011083:Polycyclic Compounds; C526360:dechlorane plus
keywords: Dechlorane Plus; Gender difference; Human hair; Serum