title: Ultrasonographic renal volume measurements in early autosomal dominant polycystic disease: comparison with CT-scan renal volume calculations.
abstract: OBJECTIVE
  To investigate the correlation and concordance between the ellipsoid volume calculated by ultrasonography measurements (Vol3DUS) and the reference kidney volume measured by CT (VolTDM) in early autosomal dominant polycystic kidney disease (ADPKD).
  
  
  METHODS
  Prospective study of the correlation and concordance of renal volumes in 24 patients with early ADPKD (48 kidneys analysed separately), with calculation of Vol3DUS using the formula for an ellipsoid in three different manners and VolTDM measurement by manual contouring. Calculations of correlation coefficients (r) and coefficients of intra-class correlation (ICC) with confidence intervals at 95%.
  
  
  RESULTS
  The US volume was strongly correlated with the CT volume by using the maximum width in a transverse section (r=0.83) with a mean Vol3DUS=692±348ml [180; 2069]. The most reproducible ultrasonography measurement was the height. When the kidney volume exceeded 800ml, US underestimated the volume. However, the median error was -57.5ml [-1090; 183] and 85% of the Vol3DUS calculated differed by more than 5% from the reference measurement.
  
  
  CONCLUSIONS
  The correlation between the US calculated volumes and the CT volumes was strong. However, the median error with ellipsoid US volume was too high to detect a small renal variation in early ADPKD.
authors.affiliation: Service de radiologie adulte, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75015 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Hammoud
authors.affiliation: Service de radiologie adulte, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75015 Paris, France.
authors.forename: A-M
authors.initials: AM
authors.lastname: Tissier
authors.affiliation: Service de biostatistique, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75015 Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Elie
authors.affiliation: Service de biostatistique, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75015 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Pousset
authors.affiliation: Service de néphrologie adulte, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75015 Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France.
authors.forename: B
authors.initials: B
authors.lastname: Knebelman
authors.affiliation: Service de néphrologie adulte, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75015 Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Joly
authors.affiliation: Service de radiologie adulte, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75015 Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France.
authors.forename: O
authors.initials: O
authors.lastname: Hélénon
authors.affiliation: Service de radiologie adulte, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75015 Paris, France; Université Paris Descartes Sorbonne Paris Cité, Paris, France; Institut Langevin - ondes et images ESPCI Paris Tech, CNRS UMR 7587 Inserm U 979, Paris, France. Electronic address: jean-michel.correas@nck.aphp.fr.
authors.forename: J-M
authors.initials: JM
authors.lastname: Correas
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D016891:Polycystic Kidney, Autosomal Dominant / Q000000981:diagnostic imaging* / Q000473:pathology*; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
keywords: CT-scan; Polycystic kidney disease; Ultrasonography; Volumetry