title: Scaling-stimulated salivary antioxidant changes and oral-health behavior in an evaluation of periodontal treatment outcomes.
abstract: OBJECTIVE
  Our goal was to investigate associations among scaling-stimulated changes in salivary antioxidants, oral-health-related behaviors and attitudes, and periodontal treatment outcomes.
  
  
  METHODS
  Thirty periodontitis patients with at least 6 pockets with pocket depths of >5 mm and more than 16 functional teeth were enrolled in the study. Patients were divided into three groups: an abandoned group (AB group), a nonprogress outcome group (NP group), and an effective treatment group (ET group). Nonstimulated saliva was collected before and after scaling were received to determine superoxide dismutase (SOD) and the total antioxidant capacity (TAOC).
  
  
  RESULTS
  Salivary SOD following scaling significantly increased from 83.09 to 194.30 U/g protein in patients who had irregular dental visit patterns (<1 visit per year). After scaling, the TAOC was significantly higher in patients who had regular dental visits than in patients who had irregular dental visits (3.52 versus 0.70 mmole/g protein, P < 0.01). The scaling-stimulated increase in SOD was related to a higher severity of periodontitis in the NP group, while the scaling-stimulated increase in the TAOC was inversely related to the severity of periodontitis in the AB group.
  
  
  CONCLUSIONS
  These results demonstrate the importance of scaling-stimulated salivary antioxidants as prognostic biomarkers of periodontal treatment.
authors.affiliation: Department of Surgery, Mackay Memorial Hospital, Mackay Medical College, Taipei 104, Taiwan ; School of Nutrition and Health Sciences, College of Public Health and Nutrition, Taipei Medical University, Taipei 110, Taiwan.
authors.forename: Po-Sheng
authors.identifier: 0000-0003-4124-8478
authors.initials: PS
authors.lastname: Yang
authors.affiliation: Dental Department, Cathay General Hospital, Taipei 106, Taiwan.
authors.forename: Wei-Chen
authors.initials: WC
authors.lastname: Huang
authors.affiliation: Dental Department, Cathay General Hospital, Taipei 106, Taiwan.
authors.forename: Shyuan-Yow
authors.identifier: 0000-0002-1841-1049
authors.initials: SY
authors.lastname: Chen
authors.affiliation: Dental Department, Cathay General Hospital, Taipei 106, Taiwan.
authors.forename: Chien-Hsun
authors.initials: CH
authors.lastname: Chen
authors.affiliation: School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei 110, Taiwan ; Division of Periodontics, Department of Dentistry, Taipei Medical University Hospital, Taipei Medical University, Taipei 110, Taiwan.
authors.forename: Chang-Yu
authors.identifier: 0000-0002-2145-8964
authors.initials: CY
authors.lastname: Lee
authors.affiliation: School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan ; Division of Prosthodontics, Department of Dentistry, Taipei Medical University Hospital, Taipei 110, Taiwan.
authors.forename: Che-Tong
authors.initials: CT
authors.lastname: Lin
authors.affiliation: School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, 250 Wu-Hsing Street, Taipei 110, Taiwan.
authors.forename: Yung-Kai
authors.identifier: 0000-0002-4467-0300
authors.initials: YK
authors.lastname: Huang
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D015415:Biomarkers / Q000378:metabolism; D005260:Female; D015438:Health Behavior; D006801:Humans; D008297:Male; D008875:Middle Aged; D009909:Oral Health; D010518:Periodontitis / Q000378:metabolism* / Q000628:therapy; D012463:Saliva / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism*
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D013482:Superoxide Dismutase