title: [Murine peritoneal neutrophil activation upon tungsten nanoparticles exposure in vivo].
abstract: Two examples of tungsten carbide nanoparticles (d = 15 nm, 50 nm) and tungsten carbide nanoparticles with 8% cobalt (d = 50 nm) have been found to induce the neutrophil activation 3 h and 36 h after intraperitoneal administration in the doses 0.005; 0.025; 0.05; 0.25; 0.5; 1; 2.5 and 5 microgram per 1 gram body weight to FVB mice. Neutrophil activation was calculated based on the CD11b and S100 antigen expression. Effect of nanoparticles is bimodal for all tested examples.
authors.forename: E A
authors.initials: EA
authors.lastname: Martinova
authors.forename: V I
authors.initials: VI
authors.lastname: Baranov
mesh_terms: D000818:Animals; D039481:CD11b Antigen / Q000235:genetics / Q000378:metabolism; D008297:Male; D053768:Metal Nanoparticles; D051379:Mice; D018375:Neutrophil Activation; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology* / Q000378:metabolism; D010537:Peritoneum / Q000166:cytology; D009418:S100 Proteins / Q000235:genetics / Q000378:metabolism; D014414:Tungsten / Q000494:pharmacology*
chemical_list: D039481:CD11b Antigen; D009418:S100 Proteins; D014414:Tungsten