title: Metastasis of prostate carcinoma in the mandible manifesting as numb chin syndrome.
abstract: BACKGROUND
  Numb chin syndrome is an uncommon but well-recognized symptom in medical oncology. This condition can be related to metastatic neurological manifestation of malignancy, often with no clinically visible pathology. About 1% of oral cancers, which are located in the soft tissues and jaws, are metastases of primary tumors located elsewhere in the body. The posterior mandible is the most common site of metastasis of the oral region because of its rich blood supply in active areas of hematopoiesis. This article describes prostate carcinoma metastasis located in the mandible and temporomandibular joint of a 78-year-old male.
  
  
  METHODS
  A 78-year-old male patient presented to our outpatient clinic with a complaint of numbness and pain on the left site of the mandible. The patient stated that he had been suffering from this numbness for 1 to 2 months. In the medical anamnesis, it was discovered that patient had prostate carcinoma (CA) 5 years previous, and since then, he had visited his doctor periodically for an annual examination. In these examinations and on the basis of tests carried out at the hospital 1 year previous, it was stated that no CA relapse traces were detected. The patient had visited his dentist 2 months previous for pain and numbness of the left molar region.
  
  
  CONCLUSIONS
  We report numb chin syndrome, which is an uncommon neurological manifestation of metastatic malignancy. The clinical course and rapid deterioration after the initial presentation of this syndrome is discussed. This clinical situation illustrates the importance of good medical history review prior to all procedures by the medical professions dealing with oncology patients. An awareness of this condition is crucial, especially in symptoms with unexplained facial pain and numbness.
authors.forename: Secil
authors.initials: S
authors.lastname: Aksoy
authors.affiliation: Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Ankara University, Besevler 06500, Ankara, Turkey. call53@yahoo.com.
authors.forename: Kaan
authors.initials: K
authors.lastname: Orhan
authors.forename: Sebnem
authors.initials: S
authors.lastname: Kursun
authors.forename: Mehmet Eray
authors.initials: ME
authors.lastname: Kolsuz
authors.forename: Berkan
authors.initials: B
authors.lastname: Celikten
mesh_terms: D000368:Aged; D002680:Chin / Q000473:pathology*; D006801:Humans; D006987:Hypesthesia / Q000209:etiology* / Q000473:pathology; D008297:Male; D008339:Mandibular Neoplasms / Q000150:complications* / Q000556:secondary; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000150:complications* / Q000473:pathology; D013577:Syndrome; D014057:Tomography, X-Ray Computed