title: Stimuli-responsive electrodes detect oxidative stress and liver injury.
abstract: A digital point-of-care biosensor for measuring reactive oxygen species is presented based on novel reactive oxygen species responsive polymer-based electrodes. The biosensor is able to detect a drug-induced liver injury by monitoring the oxidative stress in the blood.
authors.affiliation: Department of Bioengineering, University of California Berkeley, Berkeley, CA, 94720-1762, USA; Berkeley Sensors & Actuators Center, Berkeley, CA, 94720-1762, USA.
authors.forename: Kiana
authors.initials: K
authors.lastname: Aran
authors.forename: Jacobo
authors.initials: J
authors.lastname: Parades
authors.forename: Mohammad
authors.initials: M
authors.lastname: Rafi
authors.forename: Jennifer F
authors.initials: JF
authors.lastname: Yau
authors.forename: Abhinav P
authors.initials: AP
authors.lastname: Acharya
authors.forename: Mikhail
authors.initials: M
authors.lastname: Zibinsky
authors.forename: Dorian
authors.initials: D
authors.lastname: Liepmann
authors.forename: Niren
authors.initials: N
authors.lastname: Murthy
mesh_terms: D000082:Acetaminophen / Q000009:adverse effects; D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation*; D056486:Chemical and Drug Induced Liver Injury / Q000097:blood / Q000378:metabolism*; D004566:Electrodes; D017665:Hydroxyl Radical / Q000097:blood; D051379:Mice; D018384:Oxidative Stress / Q000187:drug effects; D011092:Polyethylene Glycols / Q000737:chemistry
chemical_list: D017665:Hydroxyl Radical; D000082:Acetaminophen; D011092:Polyethylene Glycols
keywords: interdigitated microelectrodes; reactive oxygen species