title: Sarcomatoid combined hepatocellular-cholangiocarcinoma: a case report and review of literature.
abstract: Sarcomatoid combined hepatocellular-cholangiocarcinoma is an extremely rare primary hepatic malignancy and only a few cases have been reported. Herein, we report a case of combined hepatocellular-cholangiocarcinoma with sarcomatoid changes in a 52-year-old man, who had a history of liver cirrhosis and transarterial chemoembolization. The resected liver revealed a mass of 4.5×3.5 cm. Microscopically, the tumor was composed of adenocarcinoma intermingled with poorly differentiated hepatocellular carcinoma, which contained atypical spindle cells. We also present a short review of reported cases of sarcomatoid combined hepatocellular-cholangiocarcinoma.
authors.affiliation: Department of Pathology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine Bucheon, Korea.
authors.forename: Susie
authors.initials: S
authors.lastname: Chin
authors.affiliation: Department of Surgery, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine Bucheon, Korea.
authors.forename: Zisun
authors.initials: Z
authors.lastname: Kim
mesh_terms: D001650:Bile Duct Neoplasms / Q000473:pathology*; D001653:Bile Ducts, Intrahepatic / Q000473:pathology*; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D018281:Cholangiocarcinoma / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D018193:Neoplasms, Complex and Mixed / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000473:pathology*
keywords: Sarcomatoid carcinoma; combined hepatocellular-cholangiocarcinoma; liver