title: Comparison of Bryan versus ProDisc-C total disk replacement as treatment for single-level cervical symptomatic degenerative disk disease.
abstract: OBJECTIVE
  The purpose of this retrospective trial was to compare the role of the Bryan with ProDisc-C total disk replacement (TDR).
  
  
  METHODS
  Data were collected before surgery and 1, 3, 6, 12, and 24 months after surgery. Disability and pain were assessed using the Neck Disability Index (NDI) and the Visual Analog Scale of the neck and of the arm pain. SF-36 outcome measures were obtained including the physical component score as well as the mental component score. Functional spinal unit (FSU) was examined on lateral radiographs at 24-month follow-up. Occurrences of heterotopic ossification (HO) were detected from 24-month follow-up X-rays.
  
  
  RESULTS
  The mean NDI, mean VAS, and mean SF-36 scores were not statistically different between groups before surgery and at 24-month follow-up. At 24 months: Bryan 49 and ProDisc-C 53 (P > 0.05). The FSU angle increased slightly for the Bryan group (from 0.7 to 0.8°, P > 0.05), while for the ProDisc-C group, it increased significantly (from 0.5 to 2.3°, P < 0.05). There were 2 additional operations in this series: 1 in the Bryan group and 1 in the ProDisc-C group. There were no intraoperative complications, no vascular or neurologic complications, no spontaneous fusions, and no device failures or explantation. No significant difference was noted in terms of HO formation.
  
  
  CONCLUSIONS
  Both the Bryan and the ProDisc-C TDR resulted in satisfactory clinical outcome. Moreover, Bryan TDR can maintain the lordosis of FSU, whereas ProDisc-C TDR can restore the lordosis of FSU, whether or not this radiographic evidence leads to more favorable clinical outcome for ProDisc-C TDR requires further investigation.
authors.affiliation: Orthopedic Department, The Affiliated Taizhou People's Hospital of Nantong University, Taizhou, 225300, Jiangsu, People's Republic of China.
authors.forename: Zhenxiang
authors.initials: Z
authors.lastname: Zhang
authors.forename: Lei
authors.initials: L
authors.lastname: Jiao
authors.forename: Wei
authors.initials: W
authors.lastname: Zhu
authors.forename: Yaqing
authors.initials: Y
authors.lastname: Du
authors.forename: Wenjie
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000328:Adult; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging / Q000601:surgery*; D017586:Diskectomy; D005260:Female; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000000981:diagnostic imaging / Q000601:surgery*; D007595:Joint Prosthesis; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012189:Retrospective Studies; D059145:Total Disc Replacement / Q000295:instrumentation*; D016896:Treatment Outcome; D055815:Young Adult