title: A prospective study on the effectiveness of newly developed autogenous tooth bone graft material for sinus bone graft procedure.
abstract: OBJECTIVE
  The purpose of this prospective study was to evaluate the effectiveness of newly developed autogenous tooth bone graft material (AutoBT)application for sinus bone graft procedure.
  
  
  METHODS
  The patients with less than 5.0 mm of residual bone height in maxillary posterior area were enrolled. For the sinus bone graft procedure, Bio-Oss was grafted in control group and AutoBT powder was grafted in experimental group. Clinical and radiographic examination were done for the comparison of grafted materials in sinus cavity between groups. At 4 months after sinus bone graft procedure, biopsy specimens were analyzed by microcomputed tomography and histomorphometric examination for the evaluation of healing state of bone graft site.
  
  
  RESULTS
  In CT evaluation, there was no difference in bone density, bone height and sinus membrane thickness between groups. In microCT analysis, there was no difference in total bone volume, new bone volume, bone mineral density of new bone between groups. There was significant difference trabecular thickness (0.07 µm in Bio-Oss group Vs. 0.08 µm in AutoBT group) (P=.006). In histomorphometric analysis, there was no difference in new bone formation, residual graft material, bone marrow space between groups. There was significant difference osteoid thickness (8.35 µm in Bio-Oss group Vs. 13.12 µm in AutoBT group) (P=.025).
  
  
  CONCLUSIONS
  AutoBT could be considered a viable alternative to the autogenous bone or other bone graft materials in sinus bone graft procedure.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Section of Dentistry, Korea University Anam Hospital, Seoul, Republic of Korea.
authors.forename: Sang-Ho
authors.initials: SH
authors.lastname: Jun
authors.affiliation: Department of Dental Biomaterials Science and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea. ; Department of Dentistry & Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
authors.forename: Jin-Soo
authors.initials: JS
authors.lastname: Ahn
authors.affiliation: Department of Dentistry & Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea. ; Department of Oral Pathology and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea.
authors.forename: Jae-Il
authors.initials: JI
authors.lastname: Lee
authors.affiliation: Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
authors.forename: Kyo-Jin
authors.initials: KJ
authors.lastname: Ahn
authors.affiliation: Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
authors.forename: Pil-Young
authors.initials: PY
authors.lastname: Yun
authors.affiliation: Department of Dentistry & Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea. ; Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
authors.forename: Young-Kyun
authors.initials: YK
authors.lastname: Kim
keywords: Bio-Oss; Sinus; Tooth