title: Distribution and drug resistance of pathogenic bacteria isolated from cancer hospital in 2013.
abstract: OBJECTIVE
  To understand distribution and drug resistance of pathogenic bacteria from a specialized cancer hospital in 2013 in order to provide a basis for rational clinical antimicrobial agents.
  
  
  METHODS
  Pathogenic bacteria identification and drug sensitivity tests were performed with a VITEK 2 compact automatic identification system and data were analyzed using WHONET5.6 software.
  
  
  RESULTS
  Of the 1,378 strains tested, 980 were Gram-negative bacilli, accounting for 71.1%, in which Klebsiella pneumonia, Escherichia coli and Pseudomonas aeruginosa were the dominant strains. We found 328 Gram-positive coccus, accounting for 23.8%, in which the amount of Staphylococcus aureus was the highest. We identified 46 fungi, accounting for 4.1%. According to the departmental distribution within the hospital, the surgical departments isolated the major strains, accounting for 49.7%. According to disease types, lung cancer, intestinal cancer and esophagus cancer were the top three, accounting for 20.9%, 17.3% and 14.2%, respectively. No strains were resistant to imipenem, ertapenem or vancomycin.
  
  
  CONCLUSIONS
  Pathogenic bacteria isolated from the specialized cancer hospital have different resistance rates compared to commonly used antimicrobial agents; therefore antimicrobial agents to reduce the morbidity and mortality of infections should be used.
authors.affiliation: 1 Department of Laboratory, 2 Department of Infection Management, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China.
authors.forename: Linjuan
authors.initials: L
authors.lastname: Liu
authors.affiliation: 1 Department of Laboratory, 2 Department of Infection Management, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Li
authors.affiliation: 1 Department of Laboratory, 2 Department of Infection Management, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China.
authors.forename: Qingyun
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: 1 Department of Laboratory, 2 Department of Infection Management, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China.
authors.forename: Guohong
authors.initials: G
authors.lastname: Wang
authors.affiliation: 1 Department of Laboratory, 2 Department of Infection Management, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China.
authors.forename: Guobin
authors.initials: G
authors.lastname: Xu
authors.affiliation: 1 Department of Laboratory, 2 Department of Infection Management, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China.
authors.forename: Ji
authors.initials: J
authors.lastname: Zhang
keywords: Tumor; distribution; drug resistance rate; pathogenic bacteria