title: Paraneoplastic pemphigus: two cases of intra-abdominal malignancy presenting solely as treatment refractory oral ulceration.
abstract: Two patients with initial diagnoses of oral lichen planus and pemphigus vulgaris presented with refractory oral mucosal blistering. Subsequent positive serology results for paraneoplastic pemphigus led to the discovery of occult intra-abdominal malignancies in both, unicentric Castleman's and non-Hodgkin's lymphoma. The diagnosis of paraneoplastic pemphigus should be considered in patients with recalcitrant oral ulceration, even in the absence of clinical features of malignancy.
authors.affiliation: Department of Immunopathology, Westmead Hospital, Sydney, New South Wales, Australia.
authors.forename: Shane
authors.initials: S
authors.lastname: Kelly
authors.forename: Mark
authors.initials: M
authors.lastname: Schifter
authors.forename: David A
authors.initials: DA
authors.lastname: Fulcher
authors.forename: Ming-Wei
authors.initials: MW
authors.lastname: Lin
mesh_terms: D000008:Abdominal Neoplasms / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D005871:Castleman Disease / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D019226:Oral Ulcer / Q000188:drug therapy / Q000209:etiology*; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D010392:Pemphigus / Q000209:etiology*
keywords: Castleman's disease; lichen planus; lymphoma; oral ulceration; paraneoplastic pemphigus