title: Prostate adenocarcinoma associated with prostatic infection due to Schistosoma haematobium. Case report and systematic review.
abstract: Schistosomiasis affects more than 240 million people worldwide, an infection which may cause urogenital manifestations including, among others, squamous bladder cancer and prostate involvement. We describe the first case of a prostate adenocarcinoma associated with prostatic Schistosoma haematobium infection occurring in Angola. Prostate carcinoma was suspected because of high levels of prostate-specific antigen. This observation prompted us to review the literature on schistosomiaisis with respect to genital pathology and prostate cancer. Described genital manifestations in men include funiculitis, epididymitis, granulomata of the seminal vesicles, testicular masses, and prostate lesions which may cause haematospermia and infertility. In contrast to bladder cancer, only 12 reports including the present case on 17 cases on prostate carcinoma associated with schistosomiasis have been published worldwide. The rarity of reports on prostate carcinoma associated with schistosomiasis is partly due to diagnostic constraints, and its incidence is underestimated. However, in emerging countries, the incidence of prostate cancer appears to increase mainly as a result of urbanization and improved access to health care where schistosomiasis prevalence is decreasing.
authors.affiliation: Urology Service, Hospital Américo Boavida, Avenida Hoji Ya Henda, Luanda, Angola.
authors.forename: Jacinta Chaves
authors.initials: JC
authors.lastname: Figueiredo
authors.forename: Joachim
authors.initials: J
authors.lastname: Richter
authors.forename: Nilo
authors.initials: N
authors.lastname: Borja
authors.forename: Antonino
authors.initials: A
authors.lastname: Balaca
authors.forename: Sandra
authors.initials: S
authors.lastname: Costa
authors.forename: Silvana
authors.initials: S
authors.lastname: Belo
authors.forename: Maria Amélia
authors.initials: MA
authors.lastname: Grácio
mesh_terms: D000230:Adenocarcinoma / Q000469:parasitology* / Q000473:pathology; D000810:Angola; D000818:Animals; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008297:Male; D011467:Prostate / Q000469:parasitology; D017430:Prostate-Specific Antigen / Q000097:blood*; D012548:Schistosoma haematobium / Q000302:isolation & purification*; D012552:Schistosomiasis / Q000469:parasitology* / Q000473:pathology; D012553:Schistosomiasis haematobia / Q000469:parasitology* / Q000473:pathology
chemical_list: D017430:Prostate-Specific Antigen