title: Peculiarity of changes of peripheral blood hematological indices in rats under N-stearoilethanolamine administration conditioned by combined effects of ionizing radiation and stress.
abstract: Objective - to investigate the peculiarities of peripheral blood indices changes in rats under the N-stearoiletanolamine treatment before and after combined effects of ionizing radiation and stress.
  
  
  METHODS
  hematological, statistical.
  
  
  RESULTS
  Per oral administration of NSE (10,0 mg / kg) before and after the combined effects of single whole-body irradiation (6.0 Gy) and emotionally-algesic stress (foot-shock) leads to reduction in the number of circulating peripheral blood cells, increasing signs of damage of the hematopoietic system with accelerated exhaustion processes. Conclusions. NSE administration (10,0 mg / kg) in rats under the combined influence of ionizing radiation (6 Gy) and emotionally-algesic stress slows down the course of regenerative processes and accelerates the depletion of the hematopoietic system, proving for its radiosensitizing effects.
authors.affiliation: State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, Melnykov str., 53, Kyiv, 04050, Ukraine. vkpand@ukr.net.
authors.forename: N K
authors.initials: NK
authors.lastname: Rоdionova
authors.affiliation: State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, Melnykov str., 53, Kyiv, 04050, Ukraine. vkpand@ukr.net.
authors.forename: N P
authors.initials: NP
authors.lastname: Аtаmaniuk
authors.affiliation: State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, Melnykov str., 53, Kyiv, 04050, Ukraine. vkpand@ukr.net.
authors.forename: L P
authors.initials: LP
authors.lastname: Dеrevyanko
authors.affiliation: State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, Melnykov str., 53, Kyiv, 04050, Ukraine. vkpand@ukr.net.
authors.forename: V V
authors.initials: VV
authors.lastname: Talko
authors.affiliation: State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, Melnykov str., 53, Kyiv, 04050, Ukraine. vkpand@ukr.net.
authors.forename: A M
authors.initials: AM
authors.lastname: Yanina
authors.affiliation: State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, Melnykov str., 53, Kyiv, 04050, Ukraine. vkpand@ukr.net.
authors.forename: M V
authors.initials: MV
authors.lastname: Shelkovskiy
authors.affiliation: A.V. Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, Leontovych str., 9a, Kyiv, 01601, Ukraine.
authors.forename: G V
authors.initials: GV
authors.lastname: Kosyakova
authors.affiliation: A.V. Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, Leontovych str., 9a, Kyiv, 01601, Ukraine.
authors.forename: O Ph
authors.initials: OP
authors.lastname: Mehed
authors.affiliation: A.V. Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, Leontovych str., 9a, Kyiv, 01601, Ukraine.
authors.forename: A G
authors.initials: AG
authors.lastname: Berdyshev
authors.affiliation: A.V. Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, Leontovych str., 9a, Kyiv, 01601, Ukraine.
authors.forename: N M
authors.initials: NM
authors.lastname: Gula
authors.affiliation: State Institution National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine, Melnykov str., 53, Kyiv, 04050, Ukraine. vkpand@ukr.net.
authors.forename: A A
authors.initials: AA
authors.lastname: Chumak
keywords: N-stearoyilethanolamine; hematological parameters; ionizing radiation; peripheral blood; rats-male; stress