title: Impact of additional genetic alterations on the outcome of patients with NPM1-mutated cytogenetically normal acute myeloid leukemia.
authors.affiliation: EA3518, Institut Universitaire d'Hématologie (IUH), University Paris Diderot, France Hematology, Centre Hospitalier Universitaire (CHU), Nantes, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Peterlin
authors.affiliation: Biology and Pathology Center, Hematology Laboratory, Centre Hospitalier Régional Universitaire (CHRU), Lille, France.
authors.forename: Aline
authors.initials: A
authors.lastname: Renneville
authors.affiliation: Hematology Laboratory, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), France.
authors.forename: Raouf
authors.initials: R
authors.lastname: Ben Abdelali
authors.affiliation: Biology and Pathology Center, Hematology Laboratory, Centre Hospitalier Régional Universitaire (CHRU), Lille, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Nibourel
authors.affiliation: Hematology, Centre Hospitalier Lyon Sud, Pierre Benite, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Thomas
authors.affiliation: Hematology, Hôpital Henri Mondor, AP-HP, Créteil, France.
authors.forename: Cécile
authors.initials: C
authors.lastname: Pautas
authors.affiliation: Hematology, Institut Gustave Roussy, Villejuif, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: de Botton
authors.affiliation: EA3518, Institut Universitaire d'Hématologie (IUH), University Paris Diderot, France Hematology, Hôpital Saint-Louis, AP-HP, Paris, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Raffoux
authors.affiliation: EA3518, Institut Universitaire d'Hématologie (IUH), University Paris Diderot, France Hematology Laboratory, Hôpital Saint-Louis, AP-HP, Paris, France.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Cayuela
authors.affiliation: EA3518, Institut Universitaire d'Hématologie (IUH), University Paris Diderot, France Hematology, Hôpital Saint-Louis, AP-HP, Paris, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Boissel
authors.affiliation: Cytogenetic Laboratory, Hôpital de Versailles, Le Chesnay, France.
authors.forename: Christine
authors.initials: C
authors.lastname: Terré
authors.affiliation: Acute Leukemia French Association (ALFA) coordination, Hôpital Saint- Louis, AP-HP, Paris, France.
authors.forename: Karine
authors.initials: K
authors.lastname: Celli-Lebras
authors.affiliation: Hematology, Hôpital de Versailles, Le Chesnay, France.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Castaigne
authors.affiliation: Biology and Pathology Center, Hematology Laboratory, Centre Hospitalier Régional Universitaire (CHRU), Lille, France.
authors.forename: Claude
authors.initials: C
authors.lastname: Preudhomme
authors.affiliation: EA3518, Institut Universitaire d'Hématologie (IUH), University Paris Diderot, France Hematology, Hôpital Avicenne, AP-HP, Bobigny, France.
authors.forename: Claude
authors.initials: C
authors.lastname: Gardin
authors.affiliation: EA3518, Institut Universitaire d'Hématologie (IUH), University Paris Diderot, France Hematology, Hôpital Saint-Louis, AP-HP, Paris, France herve.dombret@univ-paris-diderot.fr.
authors.forename: Hervé
authors.initials: H
authors.lastname: Dombret
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics; D006801:Humans; D059785:Karyotype; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000401:mortality* / Q000628:therapy; D009154:Mutation; D009687:Nuclear Proteins / Q000235:genetics*; D000090243:Nucleophosmin; D063868:Patient Outcome Assessment; D011379:Prognosis; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; C000716967:NPM1 protein, human; D009687:Nuclear Proteins; D000090243:Nucleophosmin
keywords: CN-AML heterogeneity; NPM1 mutation; cytogenetically normal