title: The Atopic Dermatitis Antecubital Severity score: validity, reliability, and sensitivity to change in patients with atopic dermatitis.
abstract: BACKGROUND
  The Atopic Dermatitis Antecubital Severity (ADAS) score is a new objective scale for the assessment of the severity of atopic dermatitis (AD). It is calculated by multiplying the intensity of inflammatory signs by the size of an antecubital eczema lesion.
  
  
  OBJECTIVE
  To test the validity, reliability, and sensitivity to changes of the ADAS score compared with those of the Eczema Area and Severity Index (EASI) score.
  
  
  METHODS
  Forty patients with AD were enrolled and treated with a moisturizer. At baseline, and in weeks 1 and 2, two independent evaluators measured the ADAS score, the EASI score, and the investigator's global assessment score rated on a six-point scale.
  
  
  RESULTS
  The ADAS score showed a higher validity than the EASI score. The superiority of the ADAS to the EASI was prominent in mild AD. Inter-evaluator reliability was excellent in both the ADAS score and the EASI. The sensitivity to changes was higher in the ADAS score than in the EASI score.
  
  
  CONCLUSIONS
  The ADAS score may be used as a simple scoring system with good validity, reliability, and sensitivity to changes, especially in patients with mild-to-moderate AD.
authors.affiliation: Dermapro/Skin Research Center, Seoul, Korea.
authors.forename: Ji Hwoon
authors.initials: JH
authors.lastname: Baek
authors.affiliation: Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
authors.forename: Chun Wook
authors.initials: CW
authors.lastname: Park
authors.affiliation: Dermapro/Skin Research Center, Seoul, Korea.
authors.forename: Kyung Min
authors.initials: KM
authors.lastname: Choi
authors.affiliation: Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
authors.forename: Yoon Seok
authors.initials: YS
authors.lastname: Yang
authors.affiliation: Dermapro/Skin Research Center, Seoul, Korea.
authors.forename: Soo Yun
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Dermapro/Skin Research Center, Seoul, Korea.
authors.forename: Jae Sook
authors.initials: JS
authors.lastname: Koh
authors.affiliation: Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
authors.forename: Bo Young
authors.initials: BY
authors.lastname: Chung
authors.affiliation: Department of Dermatology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
authors.forename: Hye One
authors.initials: HO
authors.lastname: Kim
authors.affiliation: Department of Dermatology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.
authors.forename: Gyeong-Hun
authors.initials: GH
authors.lastname: Park
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D005542:Forearm; D006801:Humans; D008297:Male; D015588:Observer Variation; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D063465:Skin Cream / Q000627:therapeutic use; D055815:Young Adult