title: Mild training program in metabolic syndrome improves the efficiency of the oxygen pathway.
abstract: In sedentary patients suffering of metabolic syndrome, we evaluated the effects of mild exercise program (EP) on the efficiency of the oxygen delivery system. The prescription of exercise (40 min/session, 3 times/week) was tailored at workload corresponding to ∼90% individual anaerobic threshold (AT). EP improved significantly by ∼10% peak values of oxygen consumption (VO2) and heart rate (HR). Furthermore, in response to steady state workload at 90% AT, EP shortened the time constant of VO2, HR and the ratio VO2/HR (reflecting arterio-venous O2 concentration difference) by ∼6s. EP also decreased the elastic respiratory work due to a change in breathing pattern implying a larger contribution of respiratory rate, at the expense of tidal volume during exercise hyperventilation. In all subjects the perceived fatigue (Borg) decreased after training. This study supports a positive effect of a mild EP for the adaptive response of the oxygen chain to face metabolic needs compatible with daily life in patients affected by metabolic syndrome.
authors.affiliation: Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Passoni
authors.affiliation: UO Recupero e Rieducazione funzionale, Ospedale Civile di Legnano, 20025 Legnano, Italy.
authors.forename: Antonino
authors.initials: A
authors.lastname: Lania
authors.affiliation: Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy.
authors.forename: Saverio
authors.initials: S
authors.lastname: Adamo
authors.affiliation: Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy.
authors.forename: Gabriele Simone
authors.initials: GS
authors.lastname: Grasso
authors.affiliation: UO Dietologia e Nutrizione Clinica, San Carlo Borromeo Hospital, 20153 Milan, Italy.
authors.forename: Donatella
authors.initials: D
authors.lastname: Noè
authors.affiliation: Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Miserocchi
authors.affiliation: Department of Health Sciences, University of Milano-Bicocca, 20900 Monza, Italy. Electronic address: egidio.beretta@unimib.it.
authors.forename: Egidio
authors.initials: E
authors.lastname: Beretta
mesh_terms: D000328:Adult; D000368:Aged; D015308:Anaerobic Threshold / Q000502:physiology; D005080:Exercise Test; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008659:Metabolic Diseases / Q000503:physiopathology* / Q000534:rehabilitation*; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology*; D010806:Physical Education and Training; D012119:Respiration; D013147:Spirometry; D013990:Tidal Volume / Q000502:physiology; D013997:Time Factors; D055815:Young Adult
keywords: Anaerobic; Exercise test; Oxygen; Work; kinetics; of breathing; threshold