title: Innovation of a new silicone prosthesis for inguinal hernioplasty: new method for silicone prosthesis production, a preliminary study.
abstract: OBJECTIVE
  The main strategy in inguinal hernia repair is mesh hernioplasty (specially prolene mesh). Pain in anterior femoral, inguinal and scrotal areas, mainly due to sensory nerve injury in the very regions and vas deferen injury are the main complications reported following repairing inguinal hernia. In this study we decided to use semiliquid silicone in order to form it in an in-vivo prosthesis production method to perform hernioplasty.
  
  
  METHODS
  In this technique, silicone was produced through Room Temperature Vulcanization (RTV) technique, which is feasible in the room temperature. The produced semiliquid polymer was shaped in the inguinal canal in six cadavers.
  
  
  RESULTS
  While the prostheses adequately covered all the anatomic area of the canal with an acceptable thickness in all of the cases, a satisfactory shape was developed in four cases. While 15 - 20 cc of silicone was needed to cover all anatomic areas properly, the hardness equal to 15 was achieved after curing process.
  
  
  CONCLUSIONS
  New silicone prosthesis forms satisfyingly in the inguinal canal and can protect it by encapsulation mechanism. It is soft with no risk of damage to the nerves or vas. It is inert and has no toxicity to the adjacent tissue. This technique of silicone remodeling can also be used in other fields of surgery such as plastic or vascular surgery.
authors.affiliation: Ziaian Hospital-Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran. fvdavari@tums.ac.ir.
authors.forename: Farzad
authors.initials: F
authors.lastname: Vaghef Davari
authors.affiliation: Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Patricia
authors.initials: P
authors.lastname: Khashayar
authors.affiliation: Biomaterial Department, Iran Polymer and Petrochemical Institute, Tehran, Iran.
authors.forename: Mohammadtaghi
authors.initials: M
authors.lastname: Khorasani
authors.affiliation: Sina Hospital-Department of Surgery, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammadreza
authors.initials: M
authors.lastname: Zafarghandi
mesh_terms: D002102:Cadaver; D005240:Feasibility Studies; D006552:Hernia, Inguinal / Q000601:surgery*; D059685:Herniorrhaphy / Q000295:instrumentation*; D006801:Humans; D007264:Inguinal Canal / Q000601:surgery*; D008953:Models, Anatomic; D019736:Prostheses and Implants; D019919:Prosthesis Implantation / Q000379:methods*; D012828:Silicones; D013526:Surgical Mesh
chemical_list: D012828:Silicones