title: Suspected hypercalcemia induced ST-segment elevation in a patient with sarcoidosis.
abstract: Sarcoidosis is a multisystem granulomatous disease that affects 10 to 20 people per 100,000 in the United States. Hypercalcemia is a known side effect of the disease and in rare instances has been shown to cause ST-segment elevation on electrocardiogram testing that mimics myocardial infarction. Herein, we present a rare case of a 55-year-old, asymptomatic African-American male with sarcoidosis and hydrochlorothiazide usage presenting with ST-segment elevation of the anterior leads secondary to hypercalcemia. Urgent cardiac catheterization showed normal coronary arteries without blockage. The patient's hypercalcemia was corrected with intravenous fluids and the ST-segment elevation resolved. The exact mechanism of ST-segment elevation induced hypercalcemia is unknown. Treatment of the underlying cause of the hypercalcemia is the mainstay of therapy.
authors.affiliation: Madigan Army Medical Center, 9040 Fitzsimmons Drive, Joint Base Lewis McChord, Tacoma, WA 98431.
authors.forename: Michael M
authors.initials: MM
authors.lastname: Braun
authors.affiliation: Madigan Army Medical Center, 9040 Fitzsimmons Drive, Joint Base Lewis McChord, Tacoma, WA 98431.
authors.forename: Keith
authors.initials: K
authors.lastname: Petersen
authors.affiliation: Madigan Army Medical Center, 9040 Fitzsimmons Drive, Joint Base Lewis McChord, Tacoma, WA 98431.
authors.forename: Sophia
authors.initials: S
authors.lastname: Hermann
authors.affiliation: Madigan Army Medical Center, 9040 Fitzsimmons Drive, Joint Base Lewis McChord, Tacoma, WA 98431.
authors.forename: Erika
authors.initials: E
authors.lastname: Overbeek-Wager
authors.affiliation: Madigan Army Medical Center, 9040 Fitzsimmons Drive, Joint Base Lewis McChord, Tacoma, WA 98431.
authors.forename: Miles
authors.initials: M
authors.lastname: Layton
authors.affiliation: Madigan Army Medical Center, 9040 Fitzsimmons Drive, Joint Base Lewis McChord, Tacoma, WA 98431.
authors.forename: David
authors.initials: D
authors.lastname: Trowbridge
mesh_terms: D002118:Calcium / Q000097:blood; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005440:Fluid Therapy; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis* / Q000503:physiopathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000503:physiopathology; D012507:Sarcoidosis / Q000150:complications*
chemical_list: D002118:Calcium