title: Prevention of ischemia-reperfusion injury in cardiac surgery: therapeutic strategies targeting signaling pathways.
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada.
authors.forename: Kay
authors.initials: K
authors.lastname: Maeda
authors.affiliation: Division of Cardiac Surgery, University of Ottawa Heart Institute, Ottawa, Ontario, Canada. Electronic address: mruel@ottawaheart.ca.
authors.forename: Marc
authors.initials: M
authors.lastname: Ruel
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D004730:Endothelium, Vascular / Q000187:drug effects*; D005464:Fluorobenzenes / Q000494:pharmacology*; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology*; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D008168:Lung / Q000187:drug effects*; D055370:Lung Injury / Q000517:prevention & control*; D008264:Macrophages / Q000187:drug effects*; D008297:Male; D052250:Nitric Oxide Synthase Type III / Q000378:metabolism*; D011743:Pyrimidines / Q000494:pharmacology*; D015427:Reperfusion Injury / Q000517:prevention & control*; D000068718:Rosuvastatin Calcium; D013449:Sulfonamides / Q000494:pharmacology*
chemical_list: D000893:Anti-Inflammatory Agents; D005464:Fluorobenzenes; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011743:Pyrimidines; D013449:Sulfonamides; D000068718:Rosuvastatin Calcium; D052250:Nitric Oxide Synthase Type III; C496316:Nos3 protein, rat