title: [Evaluation of performance of BASDAI (Bath Ankylosing Spondylitis Disease Activity Index) in a Brazilian cohort of 1,492 patients with spondyloarthritis: data from the Brazilian Registry of Spondyloarthritides (RBE)].
abstract: OBJECTIVE
  To analyze the results of the application of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in a large series of Brazilian patients with the diagnosis of SpA and establish its correlations with specific variables into the group.
  
  
  METHODS
  A common protocol of investigation was prospectively applied to 1492 Brazilian patients classified as SpA according to the European Spondyoarthropathies Study Group (ESSG), attended at 29 referral centers of Rheumatology in Brazil. Clinical and demographic variables, and disease indices (BASDAI, Basfi, Basri, Mases, ASQol) were applicated. The total values of BASDAI were compared to the presence of the different variables.
  
  
  RESULTS
  The mean score of BASDAI was 4.20 ± 2.38. The mean scores of BASDAI were higher in patients with the combined (axial + peripheral + entheseal) (4.54 ± 2.38) clinical presentation, compared to the pure axial (3.78 ± 2.27) or pure peripheral (4.00 ± 2.38) clinical presentations (p<0.001). BASDAI also presented higher scores associated with the female gender (p<0.001) and patients who did not practice exercises (p < 0.001). Regarding the axial component, higher values of BASDAI were significantly associated with inflammatory low back pain (p<0.049), alternating buttock pain (p<0.001), cervical pain (p<0.001) and hip involvement (p<0.001). There was also statistical association between BASDAI scores and the peripheral involvement, related to the lower (p=0.004) and upper limbs (p=0.025). The presence of enthesitis was also associated to higher scores of BASDAI (p=0.040). Positive HLA-B27 and the presence of cutaneous psoriasis, inflammatory bowel disease, uveitis and urethritis were not correlated with the mean scores of BASDAI. Lower scores of BASDAI were associated with the use of biologic agents (p<0.001).
  
  
  CONCLUSIONS
  In this heterogeneous Brazilian series of SpA patients, BASDAI was able to demonstrate "disease activity" in patients with axial as well as peripheral disease.
authors.affiliation: Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brasil. Electronic address: izapec@hotmail.com.
authors.forename: Izaias Pereira
authors.initials: IP
authors.lastname: da Costa
authors.affiliation: Instituto Insper de Educac¸ão e Pesquisa, São Paulo, SP, Brasil.
authors.forename: Adriana B
authors.initials: AB
authors.lastname: Bortoluzzo
authors.affiliation: Rheumatology Discipline, Universidade de São Paulo, São Paulo, SP, Brasil.
authors.forename: Célio R
authors.initials: CR
authors.lastname: Gonçalves
authors.affiliation: Universidade de Brasília, Brasília, DF, Brasil.
authors.forename: José Antonio Braga
authors.initials: JA
authors.lastname: da Silva
authors.affiliation: Hospital Geral de Goiânia, Goiânia, GO, Brasil.
authors.forename: Antonio Carlos
authors.initials: AC
authors.lastname: Ximenes
authors.affiliation: Universidade de Campinas, Campinas, SP, Brasil.
authors.forename: Manoel B
authors.initials: MB
authors.lastname: Bértolo
authors.affiliation: Universidade Federal do Amazonas, Manaus, AM, Brasil.
authors.forename: Sandra L E
authors.initials: SL
authors.lastname: Ribeiro
authors.affiliation: Pontifícia Universidade Católica, Porto Alegre, RS, Brasil.
authors.forename: Mauro
authors.initials: M
authors.lastname: Keiserman
authors.affiliation: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brasil.
authors.forename: Rita
authors.initials: R
authors.lastname: Menin
authors.affiliation: Hospital Evangélico de Curitiba, Curitiba, PR, Brasil.
authors.forename: Thelma L
authors.initials: TL
authors.lastname: Skare
authors.affiliation: Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
authors.forename: Sueli
authors.initials: S
authors.lastname: Carneiro
authors.affiliation: Universidade Federal do Paraná, Curitiba, PR, Brasil.
authors.forename: Valderílio F
authors.initials: VF
authors.lastname: Azevedo
authors.affiliation: Hospital Geral de Fortaleza, Fortaleza, CE, Brasil.
authors.forename: Walber P
authors.initials: WP
authors.lastname: Vieira
authors.affiliation: Universidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
authors.forename: Elisa N
authors.initials: EN
authors.lastname: Albuquerque
authors.affiliation: Santa Casa do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.
authors.forename: Washington A
authors.initials: WA
authors.lastname: Bianchi
authors.affiliation: Pontifícia Universidade Católica, Campinas, SP, Brasil.
authors.forename: Rubens
authors.initials: R
authors.lastname: Bonfiglioli
authors.affiliation: Santa Casa de São Paulo, São Paulo, SP, Brasil.
authors.forename: Cristiano
authors.initials: C
authors.lastname: Campanholo
authors.affiliation: Hospital de Base, Brasília, DF, Brasil.
authors.forename: Hellen M S
authors.initials: HM
authors.lastname: Carvalho
authors.affiliation: Universidade Federal de Pernambuco, Recife, PE, Brasil.
authors.forename: Angela L B Pinto
authors.initials: AL
authors.lastname: Duarte
authors.affiliation: Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
authors.forename: Charles L
authors.initials: CL
authors.lastname: Kohem
authors.affiliation: Faculdade de Medicina Souza Marques, Rio de Janeiro, RJ, Brasil.
authors.forename: Nocy H
authors.initials: NH
authors.lastname: Leite
authors.affiliation: Hospital do Servidor Público Estadual, São Paulo, SP, Brasil.
authors.forename: Sonia A L
authors.initials: SA
authors.lastname: Lima
authors.affiliation: Institute of Orthopedy and Traumatology, Universidade de São Paulo, São Paulo, SP, Brasil.
authors.forename: Eduardo S
authors.initials: ES
authors.lastname: Meirelles
authors.affiliation: Universidade Federal de Santa Catarina, Florianópolis, SC, Brasil.
authors.forename: Ivânio A
authors.initials: IA
authors.lastname: Pereira
authors.affiliation: Universidade Federal de São Paulo, São Paulo, SP, Brasil.
authors.forename: Marcelo M
authors.initials: MM
authors.lastname: Pinheiro
authors.affiliation: Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brasil.
authors.forename: Elizandra
authors.initials: E
authors.lastname: Polito
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brasil.
authors.forename: Gustavo G
authors.initials: GG
authors.lastname: Resende
authors.affiliation: Universidade Federal do Ceará, Fortaleza, CE, Brasil.
authors.forename: Francisco Airton C
authors.initials: FA
authors.lastname: Rocha
authors.affiliation: Escola de Medicina e Saúde Pública, Salvador, BA, Brasil.
authors.forename: Mittermayer B
authors.initials: MB
authors.lastname: Santiago
authors.affiliation: Universidade Federal do Pará, Belém, PA, Brasil.
authors.forename: Maria de Fátima L C
authors.initials: Mde F
authors.lastname: Sauma
authors.affiliation: Universidade Federal do Espírito Santo, Vitória, ES, Brasil.
authors.forename: Valéria
authors.initials: V
authors.lastname: Valim
authors.affiliation: Rheumatology Discipline, Universidade de São Paulo, São Paulo, SP, Brasil.
authors.forename: Percival D
authors.initials: PD
authors.lastname: Sampaio-Barros
mesh_terms: D001938:Brazil; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012042:Registries; D012720:Severity of Illness Index; D025241:Spondylarthritis / Q000175:diagnosis*; D013167:Spondylitis, Ankylosing / Q000175:diagnosis
keywords: Atividade de doença; BASDAI; Disease activity; Epidemiologia; Epidemiology; Espondiloartrites; Spondyloarthritis