title: Intussusception in Australia: epidemiology prior to the introduction of rotavirus vaccine.
abstract: OBJECTIVE
  To describe the incidence rate and clinical outcomes of intussusception in Australia in children aged <24 months prior to the use of rotavirus vaccines in Australia, and to explore associations between patient characteristics and outcomes in children with intussusception.
  
  
  METHODS
  This study used Australian national hospital discharge data on intussusception from July 2000 to June 2006 for children aged <24 months and data from the Australian Bureau of Statistics (ABS) as a proxy for population numbers to estimate incidence. Logistic regression was used to examine associations between patient characteristics (age, sex, ethnicity) and outcomes (length of hospital stay >2 days and the need for surgical intervention).
  
  
  RESULTS
  The overall incidence rate of intussusception was 5.4 per 10,000 child-years in children under 24 months (95%CI 5.17-5.70). There was a declining rate over the study period (p<0.001). Age at time of intussusception was strongly associated with length of hospital stay and surgery.
  
  
  CONCLUSIONS
  This study provides an estimate of the pre-rotavirus vaccine incidence of intussusception across Australia, which is important for monitoring the occurrence of intussusceptions post the introduction of rotavirus vaccine.
authors.affiliation: School of Population Health, University of Melbourne, Victoria; Faculty of Medicine, Universitas Gadjah Mada, Indonesia.
authors.forename: Retno
authors.initials: R
authors.lastname: Palupi-Baroto
authors.forename: Katherine J
authors.initials: KJ
authors.lastname: Lee
authors.forename: John B
authors.initials: JB
authors.lastname: Carlin
authors.forename: Julie E
authors.initials: JE
authors.lastname: Bines
mesh_terms: D000367:Age Factors; D001315:Australia / Q000453:epidemiology; D005006:Ethnicity / Q000706:statistics & numerical data*; D005260:Female; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D007223:Infant; D007443:Intussusception / Q000453:epidemiology* / Q000208:ethnology; D007902:Length of Stay / Q000706:statistics & numerical data*; D016015:Logistic Models; D008297:Male
keywords: children; epidemiology; intussusception; rotavirus vaccine