title: Case report: Treatment failure in a case of aquagenic syringeal acrokeratoderma.
abstract: Aquagenic syringeal acrokeratoderma (ASA) is a rare, acquired, recurrent, and transient type of keratoderma that may occur after a few minutes of exposure to water. Herein, an 18-year-old male patient who had bilateral swelling and whitish plaques on his palms and soles is presented. The lesions on soles and heels developed within short time of immersion in water and resolved after 30 min with drying. In this case, all treatment methods, previously described in the literature in similar cases (i.e., aluminum salts, urea-salicylic acid including ointments, iontophoresis, and botulinum toxin) were ineffective. ASA is a condition that has an adverse effect on life quality. Alternative treatments are needed in ASA cases who are resistant to treatment modalities mentioned in the literature.
authors.affiliation: Department of Dermatology and Venereology, Cerrahpasa Medical Faculty at Istanbul University , Istanbul , Turkey.
authors.forename: Zekayi
authors.initials: Z
authors.lastname: Kutlubay
authors.forename: Burhan
authors.initials: B
authors.lastname: Engin
authors.forename: Suleyman
authors.initials: S
authors.lastname: Baglam
authors.forename: Rashid
authors.initials: R
authors.lastname: Khatib
authors.forename: Cuyan
authors.initials: C
authors.lastname: Demirkesen
authors.forename: Ertugrul H
authors.initials: EH
authors.lastname: Aydemir
mesh_terms: D000293:Adolescent; D017607:Aluminum Compounds / Q000627:therapeutic use; D001905:Botulinum Toxins / Q000627:therapeutic use; D006801:Humans; D007478:Iontophoresis / Q000379:methods; D007645:Keratoderma, Palmoplantar / Q000628:therapy*; D008297:Male; D020156:Salicylic Acid / Q000627:therapeutic use; D017211:Treatment Failure
chemical_list: D017607:Aluminum Compounds; D001905:Botulinum Toxins; D020156:Salicylic Acid
keywords: aquagenic; botulinum toxin; iontophoresis; syringeal acrokeratoderma