title: Intensity modulated radiation therapy in nasopharyngeal carcinoma.
abstract: Radiation therapy (with associated chemotherapy) is the standard treatment for nasopharyngeal carcinoma. Conformal intensity-modulated radiation therapy is a new and particularly interesting technique for these tumors, due to their complex volumes close to many critical organs. Better dosimetric results and improved protection of adjacent healthy tissue have been shown compared with conventional 2D or 3D radiation therapy, with significantly reduced side-effects, notably xerostomia. Excellent local control rates have been reported.
authors.affiliation: Département d'oncologie radiothérapie, hôpital Tenon, AP-HP, groupe hospitalier des hôpitaux universitaires de l'Est Parisien (HUEP), faculté de médecine Pierre et Marie Curie, université Paris 6, 4, rue de la Chine, 75020 Paris, France. Electronic address: sophie.haberer@wanadoo.fr.
authors.forename: S
authors.initials: S
authors.lastname: Haberer-Guillerm
authors.affiliation: Département d'oncologie radiothérapie, hôpital Tenon, AP-HP, groupe hospitalier des hôpitaux universitaires de l'Est Parisien (HUEP), faculté de médecine Pierre et Marie Curie, université Paris 6, 4, rue de la Chine, 75020 Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Touboul
authors.affiliation: Département d'oncologie radiothérapie, hôpital Tenon, AP-HP, groupe hospitalier des hôpitaux universitaires de l'Est Parisien (HUEP), faculté de médecine Pierre et Marie Curie, université Paris 6, 4, rue de la Chine, 75020 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Huguet
mesh_terms: D002277:Carcinoma; D006801:Humans; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D009367:Neoplasm Staging; D011379:Prognosis; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods*; D016896:Treatment Outcome; D014987:Xerostomia / Q000517:prevention & control
keywords: Conformal intensity-modulated radiation therapy; Late effects; Nasopharyngeal carcinoma; Target volumes; Xerostomia