title: Persistent parvovirus B19 viremia with chronic arthralgia treated with ascorbic acid: a case report.
abstract: BACKGROUND
  According to some studies, ascorbic acid possesses antiviral properties. These studies were mainly focused on the common cold, with very few focusing on other viral infections.
  
  
  METHODS
  We report the case of a 54-year-old Caucasian woman with chronic arthralgia due to persistent parvovirus B19 viremia. High doses of ascorbic acid treatment were initiated due to the failure of conventional analgesic therapy. Clinical benefit was observed with a simultaneous loss of biological parvovirus B19 viremia.
  
  
  CONCLUSIONS
  This observation shows a potential benefit of the use of ascorbic acid against parvovirus B19 infections, even if this case is not sufficient to draw any definite conclusions.
authors.forename: Aloys
authors.initials: A
authors.lastname: Lallement
authors.forename: Christine
authors.initials: C
authors.lastname: Zandotti
authors.affiliation: Institut Hospitalo-Universitaire, Méditerranée Infection, AP-HM, MIT Nord, Pôle maladies infectieuses, Chemin des Bourrely, 13915 Marseille, CEDEX 20, France. philippe.brouqui@univ-amu.fr.
authors.forename: Philippe
authors.initials: P
authors.lastname: Brouqui
mesh_terms: D000914:Antibodies, Viral / Q000302:isolation & purification; D000975:Antioxidants / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use*; D018771:Arthralgia / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D001205:Ascorbic Acid / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008875:Middle Aged; D010322:Parvoviridae Infections / Q000188:drug therapy* / Q000276:immunology; D016732:Parvovirus B19, Human / Q000276:immunology / Q000302:isolation & purification*; D016896:Treatment Outcome; D014766:Viremia / Q000188:drug therapy* / Q000821:virology
chemical_list: D000914:Antibodies, Viral; D000975:Antioxidants; D000998:Antiviral Agents; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D001205:Ascorbic Acid