title: 0.5% levobupivacaine versus 0.5% ropivacaine: Are they different in ultrasound-guided sciatic block?
abstract: OBJECTIVE
  Little is known about onset and duration of sciatic block after 0.5% levobupivacaine (Levo) versus 0.5% ropivacaine (Ropi) for ultrasound-guided technique. We assessed these parameters in the ultrasound-guided block, to know for the practice.
  
  
  METHODS
  A comparative randomized double-blind study was conducted in the University Hospital.
  
  
  METHODS
  Were included 35 adults of ASA I-II, scheduled for foot surgery, presenting clear imaging of their sciatic nerve at mid-thigh. A volume of 20 mL of either 0.5% Levo or 0.5% Ropi were injected around the sciatic nerve at mid-thigh using ultrasound guidance (out of the plane) followed by placement of a catheter to use, if necessary, for perioperative analgesia. A femoral single shot block was systematically performed to block the saphenous nerve. The onset times until complete foot block (primary outcome) and the sensory and motor block duration (secondary outcome) were assessed using Wilcoxon test. Values were expressed as medians (1(st)-3(rd) quartile).
  
  
  RESULTS
  Except for two delayed sciatic blocks in each group, the onset time otherwise was 35 min (20-60) in Ropi versus 40 min (30-60) in Levo, P = 0.5. Sensory block lasted longer in Levo, 17 h (14-27) compared with 15 h (10-17) in Ropi, P = 0.04. No significant between-group difference was found with motor block durations, 15 h (12-18) in Levo and 15 h (12-16) in Ropi, P = 0.3.
  
  
  CONCLUSIONS
  No difference of onset times was found in ultrasound-guided sciatic block whether using Levo or Ropi. Levo induced a longer-lasting sensory block.
authors.affiliation: Department of Anesthesiology and Intensive Care, Hotel-Dieu, University Hospital of Nantes, 44093 France.
authors.forename: Charles
authors.initials: C
authors.lastname: Pham Dang
authors.affiliation: Department of Anesthesiology and Intensive Care, Hotel-Dieu, University Hospital of Nantes, 44093 France.
authors.forename: Cécile
authors.initials: C
authors.lastname: Langlois
authors.affiliation: Department of Anesthesiology and Intensive Care, Hotel-Dieu, University Hospital of Nantes, 44093 France.
authors.forename: Chantal
authors.initials: C
authors.lastname: Lambert
authors.affiliation: Department of Epidemiology and Biostatistics, Hopital Saint Jacques, University Hospital of Nantes, 44093 France.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Nguyen
authors.affiliation: Department of Anesthesiology and Intensive Care, Hotel-Dieu, University Hospital of Nantes, 44093 France.
authors.forename: Karim
authors.initials: K
authors.lastname: Asehnoune
authors.affiliation: Department of Anesthesiology and Intensive Care, Hotel-Dieu, University Hospital of Nantes, 44093 France.
authors.forename: Corinne
authors.initials: C
authors.lastname: Lejus
keywords: Levobupivacaine; ropivacaine; sciatic; ultrasound