title: Effect of transversus abdominis plane block on cost of laparoscopic cholecystectomy anesthesia.
abstract: BACKGROUND
  Use of transversus abdominis plane (TAP) block for postoperative analgesia is continuously increasing. However, few studies have investigated intraoperative effects of TAP block. We aimed to study the effects of TAP block in terms of cost-effectiveness and consumption of inhalation agents.
  
  
  METHODS
  Forty patients undergoing laparoscopic cholecystectomy were enrolled in this study. Patients were randomly divided into 2 groups: Group 1 (n=20) patients received TAP block and Group 2 (n=20) patients did not receive TAP block. Standard anesthesia induction was used in all patients. For the maintenance of anesthesia, fractional inspired oxygen (FIO2) of 50% in air with desflurane was used with a fresh gas flow of 4 L/min. All patients were monitored with electrocardiography and for peripheral oxygen saturation (SpO2), end-tidal carbon dioxide (ET), heart rate (HR), noninvasive mean blood pressure (MBP), and bispectral index (BIS). Bilateral TAP blocks were performed under ultrasound guidance to Group 1 patients. The BIS value was maintained at between 40 and 50 during the surgery. The Dion formula was used to calculate consumption of desflurane for each patient.
  
  
  RESULTS
  There was no difference between the groups with respect to demographic characteristics of the patients. Duration of anesthesia, surgery time, and dosage of fentanyl were similar in the 2 groups. However, the cost and consumption of desflurane was significantly lower in Group 1.
  
  
  CONCLUSIONS
  Total anesthesia consumption was lower and the cost-effectiveness of anesthesia was better in TAP block patients with general anesthesia than in non-TAP block patients undergoing laparoscopic cholecystectomy.
authors.affiliation: Department of Anesthesiology and Reanimation, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Kokulu
authors.affiliation: Department of Anesthesiology and Reanimation, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
authors.forename: Elif Doğan
authors.initials: ED
authors.lastname: Bakı
authors.affiliation: Department of Radiology, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Kaçar
authors.affiliation: Department of General Surgery, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Bal
authors.affiliation: Department of Anesthesiology and Reanimation, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Şenay
authors.affiliation: Department of Anesthesiology and Reanimation, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
authors.forename: Kübra Demir
authors.initials: KD
authors.lastname: Üstün
authors.affiliation: Department of General Surgery, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
authors.forename: Sezgin
authors.initials: S
authors.lastname: Yılmaz
authors.affiliation: Department of Anesthesiology and Reanimation, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
authors.forename: Yüksel
authors.initials: Y
authors.lastname: Ela
authors.affiliation: Department of Anesthesiology and Reanimation, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey.
authors.forename: Remziye Gül
authors.initials: RG
authors.lastname: Sıvacı
mesh_terms: D000009:Abdominal Muscles / Q000601:surgery*; D000328:Adult; D000758:Anesthesia / Q000191:economics*; D062186:Arterial Pressure; D017081:Cholecystectomy, Laparoscopic / Q000191:economics*; D000077335:Desflurane; D004305:Dose-Response Relationship, Drug; D005260:Female; D017048:Health Care Costs; D006801:Humans; D007530:Isoflurane / Q000031:analogs & derivatives / Q000191:economics / Q000494:pharmacology; D008297:Male; D008875:Middle Aged; D009407:Nerve Block / Q000191:economics*; D011897:Random Allocation; D013997:Time Factors
chemical_list: D000077335:Desflurane; D007530:Isoflurane