title: Recombinant Human Erythropoietin (RHuEpo) and Granular Colony Stimulating Factor (G-CSF) in hepatitis C virus (HCV) related to mixed cryoglobulinaemia associated to membranoproliferative glomerulonephritis type I: a case report description.
abstract: HCV infection is related to hepatic disease and mixed cryoglobulinaemia (MC). Renal involvement is reported in one third of cryoglobulinaemic patients. The combination of HCV related MC with renal involvement has been associated with poor survival and identified as Hepatitis C Virus Risk Syndrome (HCV RS). Here we describe antiviral treatment and management of side effects (anaemia and neutropenia) with RHuEpo and G CSF in a rare case of HCV RS.
authors.affiliation: Department of Internal Medicine, Pordenone General Hospital; Clinical and Experimental Onco Haematology, CRO, IRCCS, Aviano, Pordenone, Italy.
authors.forename: Endri
authors.initials: E
authors.lastname: Mauro
authors.affiliation: Department of Internal Medicine, Pordenone General Hospital; Clinical and Experimental Onco Haematology, CRO, IRCCS, Aviano, Pordenone, Italy.
authors.forename: Valter
authors.initials: V
authors.lastname: Gattei
authors.affiliation: Department of Internal Medicine, Pordenone General Hospital; Clinical and Experimental Onco Haematology, CRO, IRCCS, Aviano, Pordenone, Italy.
authors.forename: Cesare
authors.initials: C
authors.lastname: Mazzaro
mesh_terms: D000740:Anemia / Q000188:drug therapy / Q000821:virology; D000998:Antiviral Agents / Q000627:therapeutic use; D003449:Cryoglobulinemia / Q000150:complications / Q000821:virology*; D004359:Drug Therapy, Combination; D004921:Erythropoietin / Q000627:therapeutic use*; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications / Q000821:virology*; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006526:Hepatitis C / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D008103:Liver Cirrhosis / Q000188:drug therapy / Q000821:virology; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000188:drug therapy / Q000209:etiology; D011994:Recombinant Proteins / Q000627:therapeutic use; D012254:Ribavirin / Q000627:therapeutic use; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D011994:Recombinant Proteins; D004921:Erythropoietin; D016179:Granulocyte Colony-Stimulating Factor; D012254:Ribavirin; D007372:Interferons