title: Whole mitochondrial genome sequencing and analysis for rat squamous cell carcinoma tissue cell.
abstract: Mitochondrial genome plays a central role in aging, cancer, apoptosis and metabolism. Squamous cell carcinoma is one of the major types of non-small cell lung cancer. We sequenced a complete mitochondrial genome sequence of a rat squamous cell carcinomas cell tissue for the first time. The total length of the mitochondrial genome was 16,319 bp, with 13 protein-coding genes, two ribosomal RNA genes and 22 transfer RNA genes. This genome describing information will supply the potential use of mtDNA mutations as markers in cancer.
authors.affiliation: a Department of Cardiothoracic , Affiliated Huashan Hospital of Fudan University , Shanghai , China.
authors.forename: Ya-Kun
authors.initials: YK
authors.lastname: Gao
authors.affiliation: a Department of Cardiothoracic , Affiliated Huashan Hospital of Fudan University , Shanghai , China.
authors.forename: Xiao-Lin
authors.initials: XL
authors.lastname: Xu
authors.affiliation: a Department of Cardiothoracic , Affiliated Huashan Hospital of Fudan University , Shanghai , China.
authors.forename: Feng
authors.initials: F
authors.lastname: Miao
authors.affiliation: a Department of Cardiothoracic , Affiliated Huashan Hospital of Fudan University , Shanghai , China.
authors.forename: Zhi-Ming
authors.initials: ZM
authors.lastname: Chen
mesh_terms: D000818:Animals; D001483:Base Sequence; D002294:Carcinoma, Squamous Cell / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics; D050259:Genes, Mitochondrial; D054629:Genome, Mitochondrial; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D011916:Rats, Inbred F344; D017422:Sequence Analysis, DNA; D000073336:Whole Genome Sequencing
chemical_list: D004272:DNA, Mitochondrial
keywords: Cancer; mitochondrial genome; squamous cell carcinoma