title: Electroacupuncture upregulated platelet derived growth factor expression in spared dorsal root ganglion of cats.
abstract: A bilateral spared dorsal root ganglion model was established in healthy adult cats by bilateral resection of L1-5 and L7-S2 dorsal root ganglia. L6 dorsal root ganglia were spared. Zusanli (ST36) and Xuanzhong (BL39) or Futu (ST32) and Sanyinjiao (SP6) were alternatively electro-stimulated on the right leg. Immunohistochemical staining of anti-serum platelet-derived growth factor demonstrated that the number of total neurons and medium-small sized platelet-derived growth factor positive neurons was significantly decreased on the 7(th) day following injury. After 7 days of acupuncture, the total number of positive and large neurons staining for platelet-derived growth factor on the acupuncture side significantly increased compared to the non-acupuncture side. After acupuncture for 14 days, the total positive and medium-small sized neurons significantly increased compared with the non-acupuncture side. Results indicate that acupuncture promoted the synthesis of platelet-derived growth factor in spared dorsal root ganglia.
authors.affiliation: Intensive Care Unit of Yantai Yuhuangding Hospital, Yantai 264000, Shandong Province, China.
authors.forename: Xifeng
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Histology and Embryology, Binzhou Medical College, Yantai 264003, Shandong Province, China.
authors.forename: Lianshuang
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Neuroscience Department, University of Southern California, CA 90007, USA.
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Xu
authors.affiliation: Department of Histology and Embryology, Binzhou Medical College, Yantai 264003, Shandong Province, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
authors.affiliation: Department of Histology and Embryology, Binzhou Medical College, Yantai 264003, Shandong Province, China.
authors.forename: Guixiang
authors.initials: G
authors.lastname: Liu
keywords: acupuncture; cat; dorsal root ganglion; immunohistochemistry; neural morphology; neural regeneration; platelet-derived growth factor; traditional Chinese medicine