title: Copper- and cobalt-catalyzed direct coupling of sp(3) α-carbon of alcohols with alkenes and hydroperoxides.
abstract: A zerovalent copper- and cobalt-catalyzed direct coupling of the sp(3) α-carbon of alcohols with alkenes and hydroperoxides was developed in which the hydroperoxides acted as radical initiator and then coupling partner. 1,3-Enynes and vinylarenes underwent alkylation-peroxidation to give β-peroxy alcohols and β-hydroxyketones correspondingly with excellent functional group tolerance. The resulting β-peroxy alcohols could be further transformed into β-hydroxyynones and propargylic 1,3-diols.
authors.affiliation: Department of Chemistry, University of Science and Technology of China , Hefei, Anhui 230026, P.R. China.
authors.forename: Jun-Kee
authors.initials: JK
authors.lastname: Cheng
authors.forename: Teck-Peng
authors.initials: TP
authors.lastname: Loh