title: Cardioprotective effects of ghrelin in heart failure: from gut to heart.
abstract: Chronic heart failure (CHF) is a major cause of morbidity and mortality. Cardioprotective effects of ghrelin, especially in its acylated form have been demonstrated in heart failure (HF) models and exploratory human clinical studies. Hence, it has been proposed for the treatment of HF. However, the underlying mechanism of its protective effects against HF remains unclear. Future researches are needed to evaluate the efficacy of Ghrelin as a new biomarker and prognostic tool and for exploring its therapeutic potential in patients suffering from CHF.
authors.affiliation: Department of Physiology, JNMC, Wardha, Maharashtra, India.
authors.forename: Mahalaqua Nazli
authors.initials: MN
authors.lastname: Khatib
authors.affiliation: The School of Health and Related Research, The University of Sheffield, United Kingdom.
authors.forename: Padam
authors.initials: P
authors.lastname: Simkhada
authors.affiliation: Vice Chancellor, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India.
authors.forename: Dilip
authors.initials: D
authors.lastname: Gode
keywords: Cardioprotective effects; ghrelin; gut