title: Predicting and preventing vascular complications following percutaneous coronary intervention in women.
abstract: The development of vascular complications is associated with increased morbidity and mortality in patients undergoing percutaneous coronary intervention. While the incidence of percutaneous coronary intervention-related vascular complications has greatly improved over time, female sex still persists as a significant and independent predictor of periprocedural vascular complications, which in turn is associated with a greater risk of short- and long-term mortality. This review provides a contemporary overview of the data on the important issues regarding the risk of percutaneous coronary intervention in women. It examines the intrinsic sex-related factors that may be contributing to women's heightened bleeding risk while also examining the various pharmacologic and procedural bleeding avoidance strategies currently in the literature, with a focus on their potential role and benefit in women specifically.
authors.affiliation: University of California, Irvine, CA, USA.
authors.forename: Melvie
authors.initials: M
authors.lastname: Kim
authors.forename: Angela
authors.initials: A
authors.lastname: Chu
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Khan
authors.forename: Shaista
authors.initials: S
authors.lastname: Malik
mesh_terms: D005260:Female; D006470:Hemorrhage / Q000517:prevention & control*; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000517:prevention & control*; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000517:prevention & control*; D012307:Risk Factors; D012737:Sex Factors
keywords: acute coronary syndrome; bleeding; myocardial infarction; percutaneous coronary intervention; vascular complications; women