title: Percutaneous nephrolithotomy: Effect of unilateral procedure on contralateral kidney function.
abstract: BACKGROUND
  Although long-term effects of percutaneous nephrolithotomy (PCNL) on renal function and structure have been evaluated, knowledge regarding the immediate effects of surgery on renal function is limited. We conducted this study to evaluate the impact of unilateral PCNL on bilateral renal function during immediate post-operative period.
  
  
  METHODS
  From April to September 2012, 40 eligible patients were enrolled in this study and underwent unilateral PCNL. During the post-operative period, creatinine clearances (CrCl) of treated and untreated sides were estimated separately and pattern of changes in bilateral renal function following this procedure was evaluated.
  
  
  RESULTS
  Following the operation, CrCl of both kidneys showed a similar pattern of changes, of course more dramatic on treated side. We observed progressive decline in CrCl of both sides followed by bilateral improvement in renal function toward pre-operative values.
  
  
  CONCLUSIONS
  During the early post-operative period following unilateral PCNL, both kidneys experienced a temporary drop in function warranting more intensive post-operative care.
authors.affiliation: Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Mehrdad Mohammadi
authors.initials: MM
authors.lastname: Sichani
authors.affiliation: Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Amir
authors.initials: A
authors.lastname: Behnamfar
authors.affiliation: Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Mohammad Hatef
authors.initials: MH
authors.lastname: Khorami
authors.affiliation: Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Kia
authors.initials: K
authors.lastname: Nourimahdavi
authors.affiliation: Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Farshid
authors.initials: F
authors.lastname: Alizadeh
authors.affiliation: Department of Urology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Izadpanahi
keywords: Creatinine clearance; percutaneous nephrolithotomy; renal function