title: GLP-1: a mediator of the beneficial metabolic effects of bariatric surgery?
abstract: There has been increasing interest in the role that gut hormones may play in contributing to the physiological changes produced by certain bariatric procedures, such as Roux-en-Y gastric bypass and sleeve gastrectomy. Here, we review the evidence implicating one such gut hormone, glucagon-like peptide-1, as a mediator of the metabolic benefits of these two procedures.
authors.affiliation: Department of Medicine, Centre for Obesity Research, Rayne Institute, University College London, London, United Kingdom; UCLH Centre for Weight Loss, Metabolic and Endocrine Surgery, University College London Hospitals, London, United Kingdom; National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, United Kingdom.
authors.forename: Sean
authors.initials: S
authors.lastname: Manning
authors.affiliation: Department of Medicine, Centre for Obesity Research, Rayne Institute, University College London, London, United Kingdom; UCLH Centre for Weight Loss, Metabolic and Endocrine Surgery, University College London Hospitals, London, United Kingdom;
authors.forename: Andrea
authors.initials: A
authors.lastname: Pucci
authors.affiliation: Department of Medicine, Centre for Obesity Research, Rayne Institute, University College London, London, United Kingdom; UCLH Centre for Weight Loss, Metabolic and Endocrine Surgery, University College London Hospitals, London, United Kingdom; National Institute of Health Research University College London Hospitals Biomedical Research Centre, London, United Kingdom r.batterham@ucl.ac.uk.
authors.forename: Rachel L
authors.initials: RL
authors.lastname: Batterham
mesh_terms: D000818:Animals; D050110:Bariatric Surgery; D005743:Gastrectomy / Q000379:methods; D015390:Gastric Bypass; D052216:Glucagon-Like Peptide 1 / Q000378:metabolism*; D006801:Humans; D009765:Obesity / Q000378:metabolism* / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D052216:Glucagon-Like Peptide 1