title: Correlation between foveal interdigitation zone band defect and visual acuity after surgery for macular pseudohole.
abstract: OBJECTIVE
  To determine the correlation between the integrity of the foveal microstructures and the best-corrected visual acuity (BCVA) after pars plana vitrectomy for a macular pseudohole.
  
  
  METHODS
  Thirty-one eyes of 31 patients with a macular pseudohole underwent vitrectomy with internal limiting membrane removal. The foveal area was examined by spectral domain optical coherence tomography preoperatively and postoperatively. The correlations between the BCVA and the lengths of the photoreceptor interdigitation zone (IZ), the ellipsoid zone, and the external limiting membrane band defects, and central foveal thickness were determined.
  
  
  RESULTS
  The BCVA improved significantly and the length of the IZ band defect decreased significantly after the surgery. Simple linear regression analyses showed that the BCVA was significantly correlated with the length of the IZ band defect preoperatively and also at 1 to 12 months postoperatively (P < 0.001 for all). The BCVA was not significantly correlated with the length of the ellipsoid zone, external limiting membrane band defect, and the central foveal thickness.
  
  
  CONCLUSIONS
  The significant correlation between the length of the foveal IZ band defect and the BCVA preoperatively and postoperatively indicates that the foveal IZ band is related to the visual recovery in patients with macular pseudohole.
authors.affiliation: *Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan; and †Department of Ophthalmology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
authors.forename: Kazunari
authors.initials: K
authors.lastname: Hirota
authors.forename: Yuji
authors.initials: Y
authors.lastname: Itoh
authors.forename: Tosho
authors.initials: T
authors.lastname: Rii
authors.forename: Makoto
authors.initials: M
authors.lastname: Inoue
authors.forename: Akito
authors.initials: A
authors.lastname: Hirakata
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019773:Epiretinal Membrane / Q000601:surgery; D005260:Female; D005584:Fovea Centralis / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017949:Retinal Cone Photoreceptor Cells; D012167:Retinal Perforations / Q000503:physiopathology / Q000601:surgery*; D055211:Retinal Photoreceptor Cell Inner Segment / Q000473:pathology; D055214:Retinal Photoreceptor Cell Outer Segment / Q000473:pathology; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods; D014792:Visual Acuity / Q000502:physiology*; D014821:Vitrectomy