title: Relevance of age at diagnosis to prevention of late-onset group B streptococcal disease by maternal immunization.
abstract: Among 248 infants with late-onset group B streptococcal (GBS) disease from 1993 to 2012, approximately two thirds (63%) had a gestation of at least 35 weeks and 72% of these became ill within 6 weeks of life (median 27 days), suggesting that third trimester maternal GBS immunization could substantially reduce the late-onset GBS disease burden in the United States.
authors.affiliation: From the *Section of Infectious Disease, Department of Pediatrics, and †Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas; and ‡Center for Vaccine Awareness and Research, Texas Children's Hospital, Houston, Texas.
authors.forename: Morven S
authors.initials: MS
authors.lastname: Edwards
authors.forename: Marcia A
authors.initials: MA
authors.lastname: Rench
authors.forename: Carol J
authors.initials: CJ
authors.lastname: Baker
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D013290:Streptococcal Infections / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission; D013292:Streptococcus agalactiae; D013781:Texas / Q000453:epidemiology