title: Colonic mucosa-associated lymphoid tissue lymphoma identified by chromoendoscopy.
abstract: Colonic mucosa-associated lymphoid tissue (MALT) lymphomas are a rare occurrence and the definitive treatment has not been established. Solitary or multiple, elevated or polypoid lesions are the usual appearances of MALT lymphoma in the large intestine and sometimes the surface may reveal abnormal vascularity. Herein, we report a case of MALT lymphoma and review the relevant literature. Upon colonoscopy, a suspected pathologic lesion was observed in the proximal transverse colon. The lesion could be distinguished more prominently after using narrow-band imaging mode and indigo carmine-dye spraying chromoendoscopy. Histopathologic examination of this biopsy specimen revealed lymphoepithelial lesions with diffuse proliferation of atypical lymphoid cells effacing the glandular architecture and centrocyte-like cells infiltrating the lamina propria. Immunohistochemical analyses showed that tumor cells were positive for CD20 and Bcl-2e, and negative for CD10, CD23, and Bcl-6. According to Ann-Arbor staging system, the patient had stage IIE. A partial colectomy with dissection of the paracolic lymph nodes was performed. Until now, there is no recurrence of lymphoma at follow-up.
authors.affiliation: Sang-Wook Seo, Seung-Hwa Lee, Duck-Joo Lee, Kwang-Min Kim, Center for Health Promotion, Department of Family Practice and Community Health, Ajou University School of Medicine, Suwon 443-380, South Korea.
authors.forename: Sang-Wook
authors.initials: SW
authors.lastname: Seo
authors.affiliation: Sang-Wook Seo, Seung-Hwa Lee, Duck-Joo Lee, Kwang-Min Kim, Center for Health Promotion, Department of Family Practice and Community Health, Ajou University School of Medicine, Suwon 443-380, South Korea.
authors.forename: Seung-Hwa
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Sang-Wook Seo, Seung-Hwa Lee, Duck-Joo Lee, Kwang-Min Kim, Center for Health Promotion, Department of Family Practice and Community Health, Ajou University School of Medicine, Suwon 443-380, South Korea.
authors.forename: Duck-Joo
authors.initials: DJ
authors.lastname: Lee
authors.affiliation: Sang-Wook Seo, Seung-Hwa Lee, Duck-Joo Lee, Kwang-Min Kim, Center for Health Promotion, Department of Family Practice and Community Health, Ajou University School of Medicine, Suwon 443-380, South Korea.
authors.forename: Kwang-Min
authors.initials: KM
authors.lastname: Kim
authors.affiliation: Sang-Wook Seo, Seung-Hwa Lee, Duck-Joo Lee, Kwang-Min Kim, Center for Health Promotion, Department of Family Practice and Community Health, Ajou University School of Medicine, Suwon 443-380, South Korea.
authors.forename: Joon-Koo
authors.initials: JK
authors.lastname: Kang
authors.affiliation: Sang-Wook Seo, Seung-Hwa Lee, Duck-Joo Lee, Kwang-Min Kim, Center for Health Promotion, Department of Family Practice and Community Health, Ajou University School of Medicine, Suwon 443-380, South Korea.
authors.forename: Do-Wan
authors.initials: DW
authors.lastname: Kim
authors.affiliation: Sang-Wook Seo, Seung-Hwa Lee, Duck-Joo Lee, Kwang-Min Kim, Center for Health Promotion, Department of Family Practice and Community Health, Ajou University School of Medicine, Suwon 443-380, South Korea.
authors.forename: Jeong-Hun
authors.initials: JH
authors.lastname: Lee
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D002863:Chromogenic Compounds; D003082:Colectomy; D003110:Colonic Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D003113:Colonoscopy / Q000379:methods*; D006801:Humans; D007150:Immunohistochemistry; D007203:Indigo Carmine; D008197:Lymph Node Excision; D018442:Lymphoma, B-Cell, Marginal Zone / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D062048:Narrow Band Imaging / Q000379:methods*; D011237:Predictive Value of Tests; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D002863:Chromogenic Compounds; D007203:Indigo Carmine
keywords: Chromoendoscopy; Lymphoma; Mucosa-associated lymphoid tissue; Narrow-band imaging mode