title: Does tranexamic acid reduce blood transfusion cost for primary total hip arthroplasty? A case-control study.
abstract: Peri-operative tranexamic acid (TXA) significantly reduces the need for allogeneic blood transfusion in total hip arthroplasty (THA) and thus hospital costs are reduced. Before employing TXA in primary THA at our institution, facility costs were $286.90/THA for blood transfusion and required 0.45 man-hours/THA (transfusion rate 19.87%). After incorporating TXA, the cost for intravenous application was $123.38/THA for blood transfusion and TXA medication and 0.07 man-hours/THA (transfusion rate 4.39%) and the cost for topical application was $132.41/THA for blood transfusion and TXA and 0.14 man-hours/THA (transfusion rate 12.86%). TXA has the potential to reduce the facility cost per THA and the man-hours/THA from blood transfusions.
authors.affiliation: Virginia Tech Carilion School of Medicine, Roanoke, Virginia.
authors.forename: Ryan N
authors.initials: RN
authors.lastname: Harris
authors.affiliation: Orthopaedic Surgery, Carilion Clinic, Virginia Tech Carilion School of Medicine, Roanoke, Virginia; Surgery, Virginia Tech Carilion School of Medicine, Roanoke, Virginia.
authors.forename: Joseph T
authors.initials: JT
authors.lastname: Moskal
authors.affiliation: Bensol, Warsaw, Indiana.
authors.forename: Susan G
authors.initials: SG
authors.lastname: Capps
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000933:Antifibrinolytic Agents / Q000627:therapeutic use*; D019644:Arthroplasty, Replacement, Hip / Q000191:economics; D001803:Blood Transfusion / Q000191:economics*; D016022:Case-Control Studies; D005260:Female; D017721:Hospital Costs; D006801:Humans; D008297:Male; D008875:Middle Aged; D014148:Tranexamic Acid / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000933:Antifibrinolytic Agents; D014148:Tranexamic Acid
keywords: cost; hip arthroplasty; tranexamic acid; transfusion