title: Mammographic and sonographic features of triple-negative invasive carcinoma of no special type.
abstract: The aim of this study was to compare the mammography, ultrasound (US) and histologic features of triple-negative (TN) invasive carcinoma of no special type (NST) to non-TN invasive carcinoma of NST. The second aim was to assess whether the distinct imaging characteristics of TN breast cancer would persist after controlling for the histologic features. A total of 344 invasive carcinomas of NST in 337 patients from January 2007 to February 2008 were included in this study. Two radiologists retrospectively reviewed the mammography and US findings using the American College of Radiology Breast Imaging Reporting and Data System (BI-RADS) lexicon and our institution's criteria. On mammography, TN invasive carcinoma of NST most commonly presented as a mass with round shape and non-spiculated margin. On US, it was more likely to have internal hypoechogenicity, an abrupt boundary and posterior acoustic enhancement. TNBC lacked major suspicious imaging findings such as an irregular shape, spiculated margin and calcification.
authors.affiliation: Department of Diagnostic Radiology, Severance Hospital, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea; Department of Diagnostic Radiology, College of Medicine, Haeundae Paik Hospital, Inje University, Busan, Korea.
authors.forename: Hyun Kyung
authors.initials: HK
authors.lastname: Jung
authors.affiliation: Department of Diagnostic Radiology, Research Institute of Radiologic Science, Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Kyunghwa
authors.initials: K
authors.lastname: Han
authors.affiliation: Department of Diagnostic Radiology, Severance Hospital, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Yeo Jin
authors.initials: YJ
authors.lastname: Lee
authors.affiliation: Department of Diagnostic Radiology, Severance Hospital, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Hee Jung
authors.initials: HJ
authors.lastname: Moon
authors.affiliation: Department of Diagnostic Radiology, Severance Hospital, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Eun-Kyung
authors.initials: EK
authors.lastname: Kim
authors.affiliation: Department of Diagnostic Radiology, Severance Hospital, Research Institute of Radiologic Science, Yonsei University College of Medicine, Seoul, Korea. Electronic address: mines@yuhs.ac.
authors.forename: Min Jung
authors.initials: MJ
authors.lastname: Kim
mesh_terms: D001940:Breast / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000000981:diagnostic imaging; D015588:Observer Variation; D012189:Retrospective Studies; D064726:Triple Negative Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000648:ultrastructure; D016217:Ultrasonography, Mammary
keywords: Invasive carcinoma of no special type; Mammography; Triple-negative breast cancer; Ultrasound