title: Müllerian adenosarcoma: a review of cases and literature.
abstract: OBJECTIVE
  Mullerian adenosarcoma usually originates in the endometrium and grows as a polypoid mass in post-menopausal women presenting as abnormal vaginal bleeding. This report reviewed Miillerian adenosarcoma cases to clarify the clinical and pathologic characteristics.
  
  
  METHODS
  Fifteen cases ofMiillerian adenosarcoma in two medical centers covering a 15-year period were reviewed. Their clinical characteristics, pathologic findings, treatment, and outcomes were compared.
  
  
  RESULTS
  Of the 15 cases, three originated from the endometrium, six arose from uterine adenomyosis, three from the adnexa, and three from the cervix. There was only one post-menopausal case. One case was of breast cancer with tamoxifen (TMX) therapy. There were four Miillerian adenosarcoma with sarcomatous overgrowth (MASO) cases, three of which died within one year after surgery. Only the focal MASO case survived.
  
  
  CONCLUSIONS
  The rare variant of MASO is very aggressive and associated with poor prognosis.
authors.affiliation: Department of Obstetrics and Gynecology,  Taipei Tzu Chi Hospital, Taiwan. muse_Caffeine@hotmail.com
authors.forename: P S
authors.initials: PS
authors.lastname: Huang
authors.forename: W C
authors.initials: WC
authors.lastname: Chang
authors.forename: S C
authors.initials: SC
authors.lastname: Huang
mesh_terms: D018195:Adenosarcoma / Q000473:pathology / Q000628:therapy*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D014594:Uterine Neoplasms / Q000473:pathology / Q000628:therapy*