title: Anogenital granulomatosis: report of two cases.
abstract: Anogenital granulomatosis (AGG) is a rare chronic inflammatory disorder of unknown aetiology. It presents clinically with swelling of the genital or anoperineal area, with histopathological findings of noncaseating giant cell granulomas. Some cases of AGG are associated with underlying systemic disease, mainly Crohn disease. We report two patients with AGG. The first was a young man with ulcerative colitiis treated with infliximab, which also alleviated the developing symptoms of AGG. The second was a young woman who was otherwise healthy. After the introduction of complex decongestive therapy, the oedema was considerably reduced in both patients.
authors.affiliation: Department of Dermatovenereology, Faculty of Medicine, Charles University and University Teaching Hospital, Pilsen, Czech Republic.
authors.forename: T
authors.initials: T
authors.lastname: Fikrle
authors.forename: I
authors.initials: I
authors.lastname: Lomicova
authors.forename: H
authors.initials: H
authors.lastname: Szakos
authors.forename: K
authors.initials: K
authors.lastname: Pizinger
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D001004:Anus Diseases / Q000628:therapy*; D003424:Crohn Disease / Q000150:complications; D004322:Drainage / Q000379:methods; D004487:Edema / Q000628:therapy; D005260:Female; D005831:Genital Diseases, Female / Q000628:therapy*; D005832:Genital Diseases, Male / Q000628:therapy*; D006101:Granuloma, Giant Cell / Q000628:therapy*; D006801:Humans; D000069285:Infliximab; D008297:Male; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000911:Antibodies, Monoclonal; D000069285:Infliximab