title: Hepatitis C virus genotypes in Adana and Antakya regions of Turkey.
abstract: OBJECTIVE
  Hepatitis C virus (HCV) genotype 1 was found to be dominant in Turkey. In this study, HCV genotypes were examined in the Adana and Antakya regions of Turkey.
  
  
  METHODS
  The study consisted of 639 HCV-RNA-positive patients with chronic HCV infection in Adana (214 males and 101 females) and Antakya (139 males and 185 females) in Turkey. Real time-polymerase chain reaction was used for genotype determination.
  
  
  RESULTS
  In Antakya, it was determined that the percentages of genotypes of type la (0.31%), 1b (86.73%), 2 (9.26%), 3 (0.93%), and 4 (2.78%) were compatible with the nationwide results seen in Turkey. In Adana, the percentages of genotypes of type 1a (3.49%), 1b (55.24%), 2 (14.60%), 3 (26.03%), and 4 (0.63%) were found to be different. This difference was mainly due to the infection rates in males: genotype 1b was significantly lower (42.5% versus 82.2%, P < 0.001) in men in Adana, but genotype 2 (17.8% versus 7.9%, P = 0.021) and genotype 3 (34.6% versus 7.9%, P < 0.001) were significantly higher in men than in women in Adana.
  
  
  CONCLUSIONS
  Rates of genotypes 2 and 3 were unexpectedly high in Adana compared to other parts of Turkey.
authors.affiliation: Department of Family Medicine, Adana Numune Training and Research Hospital, Adana, Turkey.
authors.forename: Agah Bahadir
authors.initials: AB
authors.lastname: Oztürk
authors.forename: Umit Bilge
authors.initials: UB
authors.lastname: Doğan
authors.forename: Nevin Akçaer
authors.initials: NA
authors.lastname: Oztürk
authors.forename: Gonca
authors.initials: G
authors.lastname: Ozyazici
authors.forename: Mehmet
authors.initials: M
authors.lastname: Demir
authors.forename: Mustafa Salih
authors.initials: MS
authors.lastname: Akin
authors.forename: Ali Suha
authors.initials: AS
authors.lastname: Böngöl
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D060085:Coinfection / Q000821:virology; D003430:Cross-Sectional Studies; D005260:Female; D005838:Genotype; D016174:Hepacivirus / Q000235:genetics*; D019698:Hepatitis C, Chronic / Q000821:virology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D060888:Real-Time Polymerase Chain Reaction; D012737:Sex Factors; D014421:Turkey; D055815:Young Adult