title: Necrotic lymphoma in a patient with post-transplantation lymphoproliferative disorder: ultrasonography and CT findings with pathologic correlation.
abstract: Seventeen months after kidney transplantation for the treatment of nephrotic syndrome, a retroperitoneal mass was incidentally detected in a 30-year-old man during routine follow-up. Ultrasonography revealed a mass measuring 5.5 cm×4.3 cm located between the liver and the atrophic right kidney, which showed markedly heterogeneous internal echogenicity. Contrast-enhanced computed tomography displayed a mild degree of enhancement only at the periphery of the mass, while the center lacked perceivable intensification. The patient underwent surgical resection. The final pathological diagnosis was non-Hodgkin lymphoma (diffuse large B-cell lymphoma), and extensive necrosis was observed on microscopic examination. We found that the prominent heterogeneous echogenicity of the mass (an unusual finding of lymphoma) demonstrated on ultrasonography is a result of extensive necrosis, which may sometimes occur in patients with post-transplantation lymphoproliferative disorder.
authors.affiliation: Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea ; Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Minsu
authors.identifier: 0000-0003-1943-3677
authors.initials: M
authors.lastname: Lee
authors.affiliation: Department of Pathology, Severance Hospital, Yonsei University College of medicine, Seoul, Korea.
authors.forename: Sang Kyum
authors.identifier: 0000-0003-0768-9923
authors.initials: SK
authors.lastname: Kim
authors.affiliation: Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea ; Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Yong Eun
authors.identifier: 0000-0003-0811-9578
authors.initials: YE
authors.lastname: Chung
authors.affiliation: Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea ; Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jin-Young
authors.identifier: 0000-0002-9025-6274
authors.initials: JY
authors.lastname: Choi
authors.affiliation: Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea ; Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Mi-Suk
authors.identifier: 0000-0001-5817-2444
authors.initials: MS
authors.lastname: Park
authors.affiliation: Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea ; Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Joon Seok
authors.identifier: 0000-0002-0334-5042
authors.initials: JS
authors.lastname: Lim
authors.affiliation: Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea ; Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Myeong-Jin
authors.identifier: 0000-0001-7949-5402
authors.initials: MJ
authors.lastname: Kim
authors.affiliation: Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea ; Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Honsoul
authors.identifier: 0000-0002-2367-234X
authors.initials: H
authors.lastname: Kim
keywords: Immunocompromised host; Lymphoma; Ultrasonography