title: Curcuma ecalcarata - new natural source of pinocembrin and piperitenone.
abstract: Phytochemical analysis of the rhizome extract of Curcuma ecalcarata, a hitherto uninvestigated south Western Ghats endemic species, resulted in the isolation and identification of the diaryl heptanoid trans, trans-1,7-diphenyl-5-hydroxy-4,6-heptadiene-3-one (1), steroid β-sitosterol (2), flavanone pinocembrin (4) and monoterpenoids piperitenone (3) and 8-hydroxy piperitone (5). HPTLC estimation of pinocembrin in the rhizome revealed the plant as a rich source of pinocembrin (0.37% dry wt.). The rhizome essential oil was isolated by hydrodistillation and analysed by GC-FID, GC-MS and (13)C NMR. Among the 30 constituents identified in the oil, monoterpenoids predominated (94.2%) followed by sesquiterpenoids (5.8%). The major compound consisting of 65.2% of the oil was isolated and identified as piperitenone (3). The study highlights the plant as a rich source of the flavanone pinocembrin and the volatile aroma compound piperitenone.
authors.affiliation: a Phytochemistry and Phytopharmacology Division , Jawaharlal Nehru Tropical Botanic Garden and Research Institute , Palode, Thiruvananthapuram 695 562 , Kerala , India.
authors.forename: K B
authors.initials: KB
authors.lastname: Rameshkumar
authors.forename: D B
authors.initials: DB
authors.lastname: Alan Sheeja
authors.forename: Mangalam S
authors.initials: MS
authors.lastname: Nair
authors.forename: V
authors.initials: V
authors.lastname: George
mesh_terms: D030024:Curcuma / Q000737:chemistry*; D000081005:Cyclohexane Monoterpenes; D044950:Flavanones / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry; D027343:Rhizome / Q000737:chemistry; D012855:Sitosterols / Q000737:chemistry; D055549:Volatile Organic Compounds / Q000737:chemistry
chemical_list: D000081005:Cyclohexane Monoterpenes; D044950:Flavanones; D039821:Monoterpenes; D009822:Oils, Volatile; D010936:Plant Extracts; D010938:Plant Oils; D012855:Sitosterols; D055549:Volatile Organic Compounds; C496656:piperitone; C025473:gamma-sitosterol; C012596:turmeric extract; C016063:pinocembrin; C044956:piperitenone
keywords: Curcuma ecalcarata; GC–MS; HPTLC; essential oil; pinocembrin; piperitenone