title: Success in incorporating horizontally transferred genes: the H-NS protein.
abstract: The nucleoid-associated protein H-NS silences unwanted expression of acquired foreign DNA. Ali and colleagues recently identified which horizontally-acquired genes are targeted by H-NS in Salmonella to avoid fitness loss. The reported data strengthen our view about the role of H-NS in bacterial evolution driven by horizontal gene transfer.
authors.affiliation: Institute for Bioengineering of Catalonia (IBEC). Baldiri Reixac 15-21, 08028, Barcelona, Spain.
authors.forename: Mario
authors.initials: M
authors.lastname: Hüttener
authors.affiliation: Departament de Microbiologia, Universitat de Barcelona, 08028, Barcelona, Spain.
authors.forename: Sonia
authors.initials: S
authors.lastname: Paytubi
authors.affiliation: Institute for Bioengineering of Catalonia (IBEC). Baldiri Reixac 15-21, 08028, Barcelona, Spain; Departament de Microbiologia, Universitat de Barcelona, 08028, Barcelona, Spain. Electronic address: ajuarez@ub.edu.
authors.forename: Antonio
authors.initials: A
authors.lastname: Juárez
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000235:genetics*; D004755:Enterobacteriaceae / Q000235:genetics; D029968:Escherichia coli Proteins / Q000235:genetics; D019143:Evolution, Molecular; D020868:Gene Silencing; D022761:Gene Transfer, Horizontal; D056084:Genetic Fitness; D018832:Molecular Chaperones / Q000235:genetics; D012475:Salmonella / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; C031908:H-NS protein, bacteria; D018832:Molecular Chaperones; C090104:StpA protein, E coli; C548413:StpA protein, Salmonella typhimurium
keywords: H-NS; HGT; SPI1; Salmonella; StpA