title: Shear wave elastography in placental dysfunction: comparison of elasticity values in normal and preeclamptic pregnancies in the second trimester.
abstract: OBJECTIVE
  The aim of this study was to determine whether shear wave elastography of the placenta differs between normal pregnancies and pregnancies complicated by preeclampsia between 20 and 23 weeks' gestation.
  
  
  METHODS
  A prospective study was performed with 204 consecutive singleton pregnancies that had routine anomaly scanning between 20 and 23 weeks' gestation. One hundred twenty-nine of these patients were examined with shear wave elastography; 101 women who had clinically normal pregnancies with normal fetal biometric measurements and normal deliveries without any perinatal complications formed group A, and 28 women who had a clinical diagnosis of early-onset preeclampsia before anomaly scanning formed group B. Women with either posterior placentations (n = 63) or other obstetric disorders (n = 12) were excluded from the study.
  
  
  RESULTS
  Shear wave elastographic values for group B were significantly higher than those for group A (P < .05). No statistically significant difference was found between the elasticity values measured at the center or edge of the placenta (P > .05).
  
  
  CONCLUSIONS
  Shear wave elastography differentiates between the placental elasticity of normal pregnancies and pregnancies complicated by preeclampsia when performed during the second trimester. As a new method for tissue characterization, shear wave elastography is useful for evaluation of placental function and can be used as a supplement to existing methods for prediction of preeclampsia.
authors.affiliation: From the Departments of Radiology (C.C., I.N.A.) and Obstetrics and Gynecology (T.Y.), Marmara University Training and Research Hospital Istanbul, Turkey. canancimsit@gmail.com.
authors.forename: Canan
authors.initials: C
authors.lastname: Cimsit
authors.affiliation: From the Departments of Radiology (C.C., I.N.A.) and Obstetrics and Gynecology (T.Y.), Marmara University Training and Research Hospital Istanbul, Turkey.
authors.forename: Tevfik
authors.initials: T
authors.lastname: Yoldemir
authors.affiliation: From the Departments of Radiology (C.C., I.N.A.) and Obstetrics and Gynecology (T.Y.), Marmara University Training and Research Hospital Istanbul, Turkey.
authors.forename: Ihsan Nuri
authors.initials: IN
authors.lastname: Akpinar
mesh_terms: D000293:Adolescent; D000328:Adult; D004548:Elasticity; D054459:Elasticity Imaging Techniques; D005260:Female; D006801:Humans; D010920:Placenta / Q000000981:diagnostic imaging*; D010922:Placenta Diseases / Q000000981:diagnostic imaging*; D011225:Pre-Eclampsia / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011446:Prospective Studies; D055815:Young Adult
keywords: obstetric ultrasound; placental dysfunction; placental elasticity; preeclampsia, shear wave elastography; sonoelastography