title: A new antimicrobial and radical-scavenging glycoside from Paullinia pinnata var. cameroonensis.
abstract: A new glycoside, pinnatoside A (1), together with two known compounds (2 and 3), were isolated from the stems of Paullinia pinnata. Their structures were elucidated on the basis of extensive spectroscopic analysis and chemical methods. Compound 1 showed significant antibacterial activity with a minimum inhibitory concentration (MIC) value of 1.56 μg/mL against Escherichia coli, and 2 displayed significant antibacterial activity with a MIC value of 1.56 μg/mL against Enterobacter aerogenes and E. coli. Equally, compound 1 exhibited the best radical-scavenging activity (RSa50 = 25.07 ± 0.49 μg/mL).
authors.affiliation: a Laboratory of Microbiology and Antimicrobial Substances, Faculty of Science, University of Dschang , P.O. Box 67, Dschang , Cameroon.
authors.forename: Paul-Keilah
authors.initials: PK
authors.lastname: Lunga
authors.forename: Xu-Jie
authors.initials: XJ
authors.lastname: Qin
authors.forename: Xing-Wei
authors.initials: XW
authors.lastname: Yang
authors.forename: Jules-Roger
authors.initials: JR
authors.lastname: Kuiate
authors.forename: Zhi-Zhi
authors.initials: ZZ
authors.lastname: Du
authors.forename: Donatien
authors.initials: D
authors.lastname: Gatsing
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D032126:Paullinia / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry*; D011760:Pyrrolidinones / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D016166:Free Radical Scavengers; D005960:Glucosides; D006027:Glycosides; D010936:Plant Extracts; D011760:Pyrrolidinones; C000602376:pinnatoside A
keywords: Paullinia pinnata; antimicrobial activity; pinnatoside A; radical-scavenging activity