title: Non-invasive assessment of functional strain lines in the real human left ventricle via speckle tracking echocardiography.
abstract: A mechanics-based analysis of data from three-dimensional speckle tracking echocardiography is proposed, aimed at investigating deformations in myocardium and at assessing shape and function of distinct strain lines corresponding to the principal strain lines of the cardiac tissue. The analysis is based on the application of a protocol of measurement of the endocardial and epicardial principal strain lines, which was already tested on simulated left ventricles. In contrast with similar studies, it is established that endocardial principal strain lines cannot be identified with any structural fibers, not even along the systolic phase and is suggested that it is due to the capacity of the endocardial surface to contrast the dilation of the left ventricle.
authors.affiliation: Ospedale San Giovanni Calibita Fatebenefratelli - Isola Tiberina, Rome, Italy. Electronic address: antoevangelista@live.it.
authors.forename: A
authors.initials: A
authors.lastname: Evangelista
authors.affiliation: Dipartimento di Architettura, Università Roma Tre, Rome, Italy; LaMS - Modeling & Simulation Lab, Università Roma Tre, Rome, Italy. Electronic address: stefano.gabriele@uniroma3.it.
authors.forename: S
authors.initials: S
authors.lastname: Gabriele
authors.affiliation: Dipartimento di Ingegneria Strutturale e Geotecnica, Sapienza Università di Roma, Rome, Italy. Electronic address: paola.nardinocchi@uniroma1.it.
authors.forename: P
authors.initials: P
authors.lastname: Nardinocchi
authors.affiliation: Dipartimento di Ingegneria Strutturale e Geotecnica, Sapienza Università di Roma, Rome, Italy; Dipartimento di Scienze, Università Roma Tre, Rome, Italy; Center for Evolutionary Ecology, Rome, Italy; Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza Università di Roma, Rome, Italy. Electronic address: paolo.piras@uniroma3.it.
authors.forename: P
authors.initials: P
authors.lastname: Piras
authors.affiliation: Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza Università di Roma, Rome, Italy. Electronic address: paoloemilio.puddu@uniroma1.it.
authors.forename: P E
authors.initials: PE
authors.lastname: Puddu
authors.affiliation: Dipartimento di Matematica e Fisica, Università Roma Tre, Rome, Italy; LaMS - Modeling & Simulation Lab, Università Roma Tre, Rome, Italy. Electronic address: teresi@uniroma3.it.
authors.forename: L
authors.initials: L
authors.lastname: Teresi
authors.affiliation: Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza Università di Roma, Rome, Italy. Electronic address: concetta.torromeo@uniroma1.it.
authors.forename: C
authors.initials: C
authors.lastname: Torromeo
authors.affiliation: Dipartimento di Architettura, Università Roma Tre, Rome, Italy; LaMS - Modeling & Simulation Lab, Università Roma Tre, Rome, Italy. Electronic address: v.varano@uniroma3.it.
authors.forename: V
authors.initials: V
authors.lastname: Varano
mesh_terms: D019560:Echocardiography, Three-Dimensional; D006321:Heart / Q000502:physiology*; D006801:Humans
keywords: Cardiac mechanics; Speckle tracking echocardiography; Strain analysis; Strain imaging