title: [Peculiarities of clinical and metabolic adaptation of newborns extracted by repeated cesarean section].
abstract: The aim of the article was to study the cellular adaptation of newborn extracted by repeated cesarean section (RCS). The study of functional activity of monocytes was conducted. The activity of succinate dehydrogenase (SDG) and glutamate dehydrogenase (GDG), acid phosphatase (AP) and myeloperoxidase (MPO) of 120 newborns, extracted by RCS was determined by means of cytochemical methods. Analyses were performed in the dynamics of the neonatal period on 1-3, 5-7, 28-30 days of life of the infants. It was found that neonatal exposure to PCB on the cell membrane and intracellular structures is accompanied by high activity of the lysosomal acid phosphatase marker and low activity of mitochondrial enzymes SDG and GDG. Reduced activity of MPO from the 1st day of life and the lack of normalization of this index on the 28-30 days of life shows the exhaustion of mechanisms that determine the margin of safety of adaptive responses.
authors.forename: M A
authors.initials: MA
authors.lastname: Rzaeva
authors.forename: S Sh
authors.initials: SSh
authors.lastname: Gasanov
mesh_terms: D000135:Acid Phosphatase / Q000097:blood*; D000222:Adaptation, Physiological; D002585:Cesarean Section; D005260:Female; D005969:Glutamate Dehydrogenase / Q000097:blood*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009000:Monocytes / Q000201:enzymology; D009195:Peroxidase / Q000097:blood*; D011247:Pregnancy; D013385:Succinate Dehydrogenase / Q000097:blood*
chemical_list: D009195:Peroxidase; D013385:Succinate Dehydrogenase; D005969:Glutamate Dehydrogenase; D000135:Acid Phosphatase