title: Giant retroperitoneal ancient schwannoma: Is preoperative biopsy always mandatory?
abstract: BACKGROUND
  Schwannoma is the term given to tumours arising from Schwann cells of any nerve sheath. It may arise in the retroperitoneum, where it can attain enormous sizes and cause considerable diagnostic and therapeutic difficulties. A variety of incapacitating symptoms may arise, depending on its size alone and the related contagious organs.
  
  
  METHODS
  A 71-year-old female, who was incapacitated by a giant abdominal mass, associated with weight loss, immobility, general weakness and constipation. Radiologically, the presence of a huge pelviabdominal tumour was confirmed. A preoperative tissue diagnosis was entertained but omitted, and we resorted to direct surgical excision instead. During surgery, significant bleeding from the surrounding lumbar vessels was encountered, but it was controlled and the tumour was excised intact. Histopathologically, it showed the histologic features of ancient schwannoma.
  
  
  CONCLUSIONS
  In the patient presented here, who was rendered immobile by the tumour, total excision or at least debulking seemed appropriate, regardless of any biopsy result.
  
  
  CONCLUSIONS
  The diagnosis of retroperitoneal schwannoma and its variant "ancient schwannoma" should be considered when a huge pelviabdominal tumour is encountered. Although CT guided biopsy may be helpful in reaching a preoperative diagnosis, this might not change the decision for the need of total tumour excision or at least debulking, in the presence of incapacitating symptoms. With large tumours, the possibility of perioperative exanginating haemorrhage should be remembered and the necessary precautions activated.
authors.affiliation: Department of Surgery, Armed Forces Hospital, Southern Region, Saudi Arabia.
authors.forename: Mohammad Saad
authors.initials: MS
authors.lastname: Al Skaini
authors.affiliation: Department of Surgery, Armed Forces Hospital, Southern Region, Saudi Arabia.
authors.forename: Hesham
authors.initials: H
authors.lastname: Haroon
authors.affiliation: Department of Surgery, Armed Forces Hospital, Southern Region, Saudi Arabia.
authors.forename: Ali
authors.initials: A
authors.lastname: Sardar
authors.affiliation: Department of Radiology, Armed Forces Hospital, Southern Region, Saudi Arabia.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Bazeed
authors.affiliation: Department of Surgery, Armed Forces Hospital, Southern Region, Saudi Arabia.
authors.forename: Abbas
authors.initials: A
authors.lastname: Al Zain
authors.affiliation: Department of Surgery, Armed Forces Hospital, Southern Region, Saudi Arabia.
authors.forename: Mushabab
authors.initials: M
authors.lastname: Al Shahrani
authors.affiliation: Department of Pathology Armed Forces Hospital, Southern Region, Saudi Arabia.
authors.forename: Howaida
authors.initials: H
authors.lastname: El Hakeem
authors.affiliation: Department of Pathology, King Khalid University, Abha, Saudi Arabia.
authors.forename: Mubarak
authors.initials: M
authors.lastname: Al Shraim
authors.affiliation: Department of Surgery, Najran University, Najran, Saudi Arabia.
authors.forename: Abdul Rahman M
authors.initials: AR
authors.lastname: Al Amri
authors.affiliation: Department of Surgery, Armed Forces Hospital, Southern Region, Saudi Arabia. Electronic address: ezzedien@hotmail.com.
authors.forename: M
authors.initials: M
authors.lastname: Ezzedien Rabie
keywords: Giant; Retroperitoneum; Schwannoma