title: Successful treatment of Paecilomyces variotii peritonitis in a liver transplant patient.
abstract: Paecilomyces variotii has previously been reported as a causative pathogen for peritonitis in patients on continuous ambulatory peritoneal dialysis and shown to be usually sensitive to amphotericin B and resistant to voriconazole. We report the first case, to our knowledge, of P. variotii peritonitis in a liver transplant patient, which was unresponsive to initial liposomal amphotericin B (L-AmB) treatment and resolved dramatically after the addition of voriconazole. The present case provides evidence for the clinical and microbiological effectiveness of voriconazole combined with L-AmB in treating P. variotii peritonitis refractory to initial L-AmB treatment.
authors.affiliation: Department of Pediatric Infectious Diseases, Gazi University School of Medicine, 06500, Beşevler, Ankara, Turkey, meltemtemizhan@gmail.com.
authors.forename: Meltem
authors.initials: M
authors.lastname: Polat
authors.forename: Soner Sertan
authors.initials: SS
authors.lastname: Kara
authors.forename: Anıl
authors.initials: A
authors.lastname: Tapısız
authors.forename: Zeliha
authors.initials: Z
authors.lastname: Demirtaş
authors.forename: Sinan
authors.initials: S
authors.lastname: Sarı
authors.forename: Ayşe
authors.initials: A
authors.lastname: Kalkancı
authors.forename: Hasan
authors.initials: H
authors.lastname: Tezer
authors.forename: Buket
authors.initials: B
authors.lastname: Dalgıç
mesh_terms: D000293:Adolescent; D000935:Antifungal Agents / Q000008:administration & dosage; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D009181:Mycoses / Q000188:drug therapy* / Q000382:microbiology; D010143:Paecilomyces / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D010538:Peritonitis / Q000188:drug therapy* / Q000382:microbiology; D011183:Postoperative Complications / Q000188:drug therapy* / Q000382:microbiology; D065819:Voriconazole / Q000008:administration & dosage
chemical_list: D000935:Antifungal Agents; D065819:Voriconazole