title: Hazardous drinking-related characteristics of depressive disorders in Korea: the CRESCEND study.
abstract: This study aimed to identify clinical correlates of hazardous drinking in a large cohort of Korean patients with depression. We recruited a total of 402 depressed patients aged > 18 yr from the Clinical Research Center for Depression (CRESCEND) study in Korea. Patients' drinking habits were assessed using the Korean Alcohol Use Disorder Identification Test (AUDIT-K). Psychometric scales, including the HAMD, HAMA, BPRS, CGI-S, SSI-Beck, SOFAS, and WHOQOL-BREF, were used to assess depression, anxiety, overall psychiatric symptoms, global severity, suicidal ideation, social functioning, and quality of life, respectively. We compared demographic and clinical features and psychometric scores between patients with and without hazardous drinking behavior after adjusting for the effects of age and sex. We then performed binary logistic regression analysis to identify independent correlates of hazardous drinking in the study population. Our results revealed that hazardous drinking was associated with current smoking status, history of attempted suicide, greater psychomotor retardation, suicidal ideation, weight loss, and lower hypochondriasis than non-hazardous drinking. The regression model also demonstrated that more frequent smoking, higher levels of suicidal ideation, and lower levels of hypochondriasis were independently correlates for hazardous drinking in depressed patients. In conclusion, depressed patients who are hazardous drinkers experience severer symptoms and a greater burden of illness than non-hazardous drinkers. In Korea, screening depressed patients for signs of hazardous drinking could help identify subjects who may benefit from comprehensive therapeutic approaches.
authors.affiliation: Department of Psychiatry, Yong-In Mental Hospital, Yongin, Korea. ; Institute of Mental Health, Hanyang University, Seoul, Korea.
authors.forename: Seon-Cheol
authors.identifier: 0000-0003-3691-4624
authors.initials: SC
authors.lastname: Park
authors.affiliation: Department of Psychiatry, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Korea.
authors.forename: Sang Kyu
authors.identifier: 0000-0001-6714-850X
authors.initials: SK
authors.lastname: Lee
authors.affiliation: Department of Psychiatry, Yong-In Mental Hospital, Yongin, Korea.
authors.forename: Hong Seok
authors.identifier: 0000-0002-3071-3760
authors.initials: HS
authors.lastname: Oh
authors.affiliation: Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Tae-Youn
authors.identifier: 0000-0001-9516-0768
authors.initials: TY
authors.lastname: Jun
authors.affiliation: Department of Psychiatry, Korea University College of Medicine, Seoul, Korea.
authors.forename: Min-Soo
authors.identifier: 0000-0002-3483-4375
authors.initials: MS
authors.lastname: Lee
authors.affiliation: Department of Psychiatry, Chonnam National University School of Medicine, Gwangju, Korea.
authors.forename: Jae-Min
authors.identifier: 0000-0001-7409-6306
authors.initials: JM
authors.lastname: Kim
authors.affiliation: Department of Psychiatry, Keimyung University School of Medicine, Daegu, Korea.
authors.forename: Jung-Bum
authors.identifier: 0000-0001-9444-1437
authors.initials: JB
authors.lastname: Kim
authors.affiliation: Department of Preventive Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors.forename: Hyeon-Woo
authors.identifier: 0000-0002-3646-8161
authors.initials: HW
authors.lastname: Yim
authors.affiliation: Institute of Mental Health, Hanyang University, Seoul, Korea. ; Department of Psychiatry, Hanyang University College Guri Hospital, Guri, Korea.
authors.forename: Yong Chon
authors.identifier: 0000-0002-3019-5748
authors.initials: YC
authors.lastname: Park
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000453:epidemiology*; D000437:Alcoholism / Q000453:epidemiology* / Q000523:psychology; D003617:Dangerous Behavior; D003866:Depressive Disorder / Q000453:epidemiology* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D011788:Quality of Life; D056910:Republic of Korea / Q000453:epidemiology; D059020:Suicidal Ideation
keywords: Depressive Disorders; Hazardous Drinking; Hypochondriasis; Smoking; Suicidal Ideation