title: [Cannabinoid hyperemesis syndrome: about 6 cases].
abstract: BACKGROUND
  The cannabinoid hyperemesis syndrome (CHS) is characterized by cyclic episodes of nausea, vomiting, and abdominal pain, and occurs in young adults with long-term cannabis use. The feature of this syndrome is the relief of symptoms with hot showers. We report here six cases report.
  
  
  METHODS
  Three women and 3 men, chronic consumers of cannabis, presented with typical features of the CHS, but the syndrome remained undiagnosed until then: nausea, vomiting, abdominal pain with morning ascendancy and loss of weight occurring in adult's of less than 50 years. The symptoms were improved by taking repeated hot showers. The medical investigations were negative. After addictologist care and cannabis weaning, digestive symptoms disappeared.
  
  
  CONCLUSIONS
  The CHS is based on a clinical diagnosis. When undiagnosed, clinical presentation leads to a medical wandering and to the realization of repeated, expensive, and sometimes invasive exams. The physiopathology is not clear. The treatment relies on the definitive cannabis weaning.
authors.affiliation: Service de médecine interne, hôpital Nord, Assistance publique-Hôpitaux de Marseille (AP-HM), chemin des Bourrely, 13915 Marseille cedex 15, France; Université d'Aix-Marseille , 13284 Marseille, France.
authors.forename: J
authors.initials: J
authors.lastname: Bertolino
authors.affiliation: Service de médecine interne, hôpital Saint-Antoine, Assistance publique-Hôpitaux de Paris (AP-HP), 75571 Paris, France.
authors.forename: L
authors.initials: L
authors.lastname: Abdo
authors.affiliation: Service de médecine interne et maladies infectieuses, centre hospitalier de Versailles, 78150 Le Chesnay, France.
authors.forename: D
authors.initials: D
authors.lastname: Khau
authors.affiliation: Service de médecine interne et maladies infectieuses, centre hospitalier de Versailles, 78150 Le Chesnay, France.
authors.forename: R
authors.initials: R
authors.lastname: Meckenstock
authors.affiliation: Service de médecine interne, hôpital Nord, Assistance publique-Hôpitaux de Marseille (AP-HM), chemin des Bourrely, 13915 Marseille cedex 15, France; Université d'Aix-Marseille , 13284 Marseille, France.
authors.forename: N
authors.initials: N
authors.lastname: Sautereau
authors.affiliation: Service de médecine interne, hôpital Nord, Assistance publique-Hôpitaux de Marseille (AP-HM), chemin des Bourrely, 13915 Marseille cedex 15, France; Université d'Aix-Marseille , 13284 Marseille, France.
authors.forename: E
authors.initials: E
authors.lastname: Jean
authors.affiliation: Service de médecine interne et maladies infectieuses, centre hospitalier de Versailles, 78150 Le Chesnay, France.
authors.forename: A
authors.initials: A
authors.lastname: Greder-Belan
authors.affiliation: Service de médecine interne, hôpital Nord, Assistance publique-Hôpitaux de Marseille (AP-HM), chemin des Bourrely, 13915 Marseille cedex 15, France; Université d'Aix-Marseille , 13284 Marseille, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Frances
authors.affiliation: Service de médecine interne, hôpital Saint-Antoine, Assistance publique-Hôpitaux de Paris (AP-HP), 75571 Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Cabane
authors.affiliation: Service de médecine interne, hôpital Nord, Assistance publique-Hôpitaux de Marseille (AP-HM), chemin des Bourrely, 13915 Marseille cedex 15, France; Université d'Aix-Marseille , 13284 Marseille, France. Electronic address: bgranel@ap-hm.fr.
authors.forename: B
authors.initials: B
authors.lastname: Granel
mesh_terms: D000328:Adult; D002186:Cannabinoids / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D002189:Marijuana Abuse / Q000150:complications*; D008875:Middle Aged; D009325:Nausea / Q000175:diagnosis / Q000209:etiology*; D013577:Syndrome; D014839:Vomiting / Q000175:diagnosis / Q000209:etiology*
chemical_list: D002186:Cannabinoids
keywords: Cannabinoid hyperemesis syndrome; Cannabis; Douches chaudes; Hot showers; Syndrome d’hyperémèse cannabique; Vomissement; Vomiting