title: Geoherbalism evaluation of Radix Angelica sinensis based on electronic nose.
abstract: Radix Angelica sinensis (Danggui, DG), derived from the dry root of Angelicae sinensis, is popularly used for its antioxidant, hematinic and immuno-enhancement. However, DG from different origins possess different quality, and difficult to identity. In this study, we used electronic nose technique to investigate DG from different producing areas for monitoring the correlation of origin and quality. The electronic nose was employed to establish classification model of DG originated from four main producing areas of Gansu, Yunnan, Sichuan and Hubei in China. Principal component analysis (PCA) and discriminant function analysis (DFA) were performed to differentiate DG samples from four main producing areas. The content of phthalides of DG were determined to confirm the quality changes and investigate its correlation with the odor response values by Gas Chromatography-Mass Spectrometer (GC-MS). The results of PCA and DFA analysis showed that the electronic nose could accurately distinguish DG from four main producing areas. The method of electronic nose for identification could be verified by GC-MS technology, and the main ingredient content was consistent with its odor of DG. In conclusion, electronic nose could effectively identify different origins of DG, and could be applied for rapid identification and quality control of genuine Angelica herbs.
authors.affiliation: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. Electronic address: zshzha@gmail.com.
authors.forename: Sihao
authors.initials: S
authors.lastname: Zheng
authors.affiliation: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China; Guang' anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China.
authors.forename: Weiguang
authors.initials: W
authors.lastname: Ren
authors.affiliation: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, China. Electronic address: lfhuang@implad.ac.cn.
authors.forename: Linfang
authors.initials: L
authors.lastname: Huang
mesh_terms: D029971:Angelica sinensis / Q000737:chemistry* / Q000254:growth & development; D002681:China; D004365:Drugs, Chinese Herbal / Q000032:analysis* / Q000302:isolation & purification; D062609:Electronic Nose; D008401:Gas Chromatography-Mass Spectrometry; D062306:Geography, Medical; D018517:Plant Roots / Q000737:chemistry; D025341:Principal Component Analysis; D013045:Species Specificity; D055549:Volatile Organic Compounds / Q000032:analysis*
chemical_list: D004365:Drugs, Chinese Herbal; D055549:Volatile Organic Compounds; C044613:angelicae sinensis extract
keywords: Electronic nose; Geoherbalism; Identification; Radix Angelicae Sinensis