title: Treating type-1 diabetes with an epigenetic drug.
abstract: A single drug treats type-1 diabetes in mice by dampening inflammation and enhancing insulin production.
authors.affiliation: Department of Experimental Immunology, World Premier International Immunology Frontier Research Center, Osaka University, Suita, Japan.
authors.forename: Yohko
authors.initials: Y
authors.lastname: Kitagawa
authors.affiliation: Department of Experimental Immunology, World Premier International Immunology Frontier Research Center, the Department of Frontier Research in Tumor Immunology, Graduate School of Medicine, and the Center of Medical Innovation & Translational Research, Osaka University, Suita, Japan nohkura@ifrec.osaka-u.ac.jp.
authors.forename: Naganari
authors.initials: N
authors.lastname: Ohkura
mesh_terms: D000818:Animals; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics*; D044127:Epigenesis, Genetic; D005260:Female; D050417:Insulin-Secreting Cells / Q000473:pathology*; D008264:Macrophages / Q000473:pathology*
keywords: NF-KB; autoimmune diabetes; bromodomain inhibitor; immunology; mouse