title: Neonatal pulmonary artery reconstruction during shunting to treat and prevent juxtaductal coarctation.
abstract: BACKGROUND
  Coarctation of the pulmonary artery may lead to its early obstruction. We investigated the outcomes of a strategy of aggressive reconstruction of the pulmonary arteries in the neonatal period.
  
  
  METHODS
  From 2000 to 2013 a total of 162 consecutive neonates (< 90 days) underwent systemic-to-pulmonary shunting. Twenty-eight of them underwent the following concomitant reconstruction of the central pulmonary arteries: end-to-end anastomosis (4), patch reconstruction of the pulmonary arteries (24) with 0.4 mm Gore-Tex (W. L. Gore & Associates, Newark, DE) patch (18), or autologous pericardium (6). Ten patients were directed to univentricular palliation and 18 to biventricular repair.
  
  
  RESULTS
  There was 1 in-hospital death (4%) and 2 deaths after hospital discharge (inter-stage mortality, 7%). The follow-up of the 25 survivors was complete. After a mean of 3 ± 3 years, patients with single ventricle palliation reached the following stages: shunts (2); one and a half ventricle repair (1); bidirectional cavopulmonary shunt (4); and Fontan (2). Fourteen of the patients destined for biventricular physiology reached complete repair while 2 patients were still with shunts. There was no pulmonary artery occlusion. Focal narrowing or pulmonary artery hypoplasia was the main indication for 10 of the subsequent 36 reinterventions.
  
  
  CONCLUSIONS
  Neonatal pulmonary artery reconstruction effectively prevents pulmonary artery occlusion and warrants pulmonary artery growth in the majority of cases of juxtaductal pulmonary artery coarctation. A number of these patients needed enlargement of their central pulmonary arteries in subsequent procedures. Indications of this reconstruction at the time of systemic-to-pulmonary shunting remains to be specified.
authors.affiliation: Department of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Victoria, Australia.
authors.forename: Johann
authors.initials: J
authors.lastname: Brink
authors.affiliation: Department of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Victoria, Australia.
authors.forename: Robroy
authors.initials: R
authors.lastname: MacIver
authors.affiliation: Department of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Victoria, Australia; Department of Paediatrics of the University of Melbourne, Melbourne, Victoria, Australia; Murdoch Childrens Research Institute, Parkville, Victoria, Australia.
authors.forename: Melissa G Y
authors.initials: MG
authors.lastname: Lee
authors.affiliation: Department of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Victoria, Australia; Department of Paediatrics of the University of Melbourne, Melbourne, Victoria, Australia; Murdoch Childrens Research Institute, Parkville, Victoria, Australia.
authors.forename: Igor E
authors.initials: IE
authors.lastname: Konstantinov
authors.affiliation: Department of Paediatrics of the University of Melbourne, Melbourne, Victoria, Australia; Department of Cardiology, The Royal Children's Hospital, Melbourne, Victoria, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Cheung
authors.affiliation: Department of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Victoria, Australia; Department of Paediatrics of the University of Melbourne, Melbourne, Victoria, Australia; Murdoch Childrens Research Institute, Parkville, Victoria, Australia.
authors.forename: Christian P
authors.initials: CP
authors.lastname: Brizard
authors.affiliation: Department of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Victoria, Australia; Department of Paediatrics of the University of Melbourne, Melbourne, Victoria, Australia; Murdoch Childrens Research Institute, Parkville, Victoria, Australia. Electronic address: yves.dudekem@rch.org.au.
authors.forename: Yves
authors.initials: Y
authors.lastname: d'Udekem
mesh_terms: D000015:Abnormalities, Multiple / Q000601:surgery*; D006348:Cardiac Surgical Procedures / Q000379:methods; D005260:Female; D006330:Heart Defects, Congenital / Q000601:surgery*; D006352:Heart Ventricles / Q000002:abnormalities* / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011651:Pulmonary Artery / Q000002:abnormalities* / Q000601:surgery*; D012189:Retrospective Studies; D014656:Vascular Surgical Procedures / Q000379:methods