title: Artificial hydrogenases: biohybrid and supramolecular systems for catalytic hydrogen production or uptake.
abstract: There is an urgent need for cheap, abundant and efficient catalysts as an alternative to platinum for hydrogen production and oxidation in (photo)electrolyzers and fuel cells. Hydrogenases are attractive solutions. These enzymes use exclusively nickel and iron in their active sites and function with high catalytic rates at the thermodynamic equilibrium. As an alternative, a number of biomimetic and bioinspired catalysts for H2 production and/or uptake, based on Ni, Fe and Co, have been developed and shown to display encouraging performances. In this review we discuss specifically recent approaches aiming at incorporating these compounds within oligomeric and polymeric hosts. The latter are most often biological compounds (peptides, proteins, polysaccharides, etc.) but we also discuss non-biological scaffolds (synthetic polymers, Metal-organic-Frameworks, etc.) which can provide the appropriate environment to tune the activity and stability of the synthetic catalysts. These supramolecular catalytic systems thus define a class of original compounds so-called artificial hydrogenases.
authors.affiliation: Laboratoire de Chimie des Processus Biologiques, Collège de France, CNRS, Université P. et M. Curie, 11 Place Marcelin Berthelot, 75231 Paris Cedex 05, France.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Caserta
authors.affiliation: Laboratoire de Chimie et Biologie des Métaux, Université Grenoble Alpes, CEA Life Science Division, CNRS, 17 rue des Martyrs, F-38054 Grenoble Cedex 9, France.
authors.forename: Souvik
authors.initials: S
authors.lastname: Roy
authors.affiliation: Laboratoire de Chimie et Biologie des Métaux, Université Grenoble Alpes, CEA Life Science Division, CNRS, 17 rue des Martyrs, F-38054 Grenoble Cedex 9, France.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Atta
authors.affiliation: Laboratoire de Chimie et Biologie des Métaux, Université Grenoble Alpes, CEA Life Science Division, CNRS, 17 rue des Martyrs, F-38054 Grenoble Cedex 9, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Artero
authors.affiliation: Laboratoire de Chimie des Processus Biologiques, Collège de France, CNRS, Université P. et M. Curie, 11 Place Marcelin Berthelot, 75231 Paris Cedex 05, France; Laboratoire de Chimie et Biologie des Métaux, Université Grenoble Alpes, CEA Life Science Division, CNRS, 17 rue des Martyrs, F-38054 Grenoble Cedex 9, France. Electronic address: marc.fontecave@cea.fr.
authors.forename: Marc
authors.initials: M
authors.lastname: Fontecave
mesh_terms: D000595:Amino Acid Sequence; D040761:Biomimetic Materials / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry*; D006864:Hydrogenase / Q000737:chemistry / Q000378:metabolism*; D008969:Molecular Sequence Data; D009942:Organometallic Compounds / Q000737:chemistry
chemical_list: D009942:Organometallic Compounds; D006859:Hydrogen; D006864:Hydrogenase