title: Primary malignant melanoma of esophagus: a case report and review of literature.
abstract: Primary malignant melanoma of esophagus is a rare but highly aggressive neoplasm, with an incidence less than 0.2% of all primary esophagus neoplasms. There are no clinical differences from other forms of esophagus cancer. Because initial symptoms are nonspecific, the patients are usually diagnosed at a late stage. The prognosis is poor, and curative effect seems disappointed. Several reports suggest that most of patients die from distant metastases, and the 5-year survival rate is approximately 4.2%. This case report includes a review of the surgical pathology, clinical features and treatment of primary malignant melanoma of esophagus. This case report presents a 56-year-old female with primary malignant melanoma of esophagus, treated by surgical resection. Till now, the patient is still alive for 5 months without any chemotherapy, radiotherapy and immunomodulatory therapy.
authors.affiliation: Department of Pathology, Tangshan Gongren Hospital Tangshan, China.
authors.forename: Yue-Ming
authors.initials: YM
authors.lastname: Hu
authors.affiliation: Department of Thoracic Surgery, Tangshan Gongren Hospital Tangshan, China.
authors.forename: Ji-Dong
authors.initials: JD
authors.lastname: Yan
authors.affiliation: Department of Thoracic Surgery, Tangshan Gongren Hospital Tangshan, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Department of Pathology, Tangshan Gongren Hospital Tangshan, China.
authors.forename: Qing-An
authors.initials: QA
authors.lastname: Xia
authors.affiliation: Department of Pathology, Tangshan Gongren Hospital Tangshan, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of Pathology, Tangshan Gongren Hospital Tangshan, China.
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Zhang
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged
chemical_list: D014408:Biomarkers, Tumor
keywords: Malignant melanoma; esophagus neoplasm; immunohistochemistry