title: Risk of bleeding after native renal biopsy as a function of preprocedural systolic and diastolic blood pressure.
abstract: OBJECTIVE
  To determine the risk of bleeding complications after native renal biopsy as a function of preprocedural blood pressure (BP).
  
  
  METHODS
  A total of 293 patients (163 men; mean age, 59.1 y) who underwent ultrasound-guided native kidney biopsy at a single institution over a 10-year period were retrospectively identified. Demographic and clinical data were collected, including systolic BP (SBP) and diastolic BP (DBP) at the time of the biopsy and presence and severity of complications. Differences in clinical and demographic data among patients with and without complications were analyzed.
  
  
  RESULTS
  Of 293 patients, nine (3.1%) experienced major complications (required transfusion or intervention) and 10 (3.4%) experienced minor complications (pain, hematoma, or hematuria). Patients with SBP greater than 140 mm Hg or DBP greater than 90 mm Hg were 10 times more likely to experience major complications (P < .02) than patients without high BP (odds ratio [OR], 10.6; 95% confidence interval [CI], 1.3-86.0). The odds of complications were particularly increased in patients with SBP greater than 170 mm Hg (OR, 23.3; 95% CI, 2.3-234.4) and were modestly increased in patients with SBP between 141 and 170 mm Hg (OR, 7.11; 95% CI, 0.8-61.7). For DBP, the odds of complications increased with DBP greater than 90 mm Hg (OR, 7.2; 95% CI, 1.9-27.9).
  
  
  CONCLUSIONS
  Patients undergoing native renal biopsy who have an SBP greater than 140 mm Hg or DBP greater than 90 mm Hg are at higher risk for bleeding complications. Further research is needed to determine whether medically lowering these patients' BP before kidney biopsy decreases complications.
authors.affiliation: Department of Radiology, Mayo Clinic Hospital, 5777 E. Mayo Blvd., Phoenix, AZ 85054. Electronic address: skriegshauser@mayo.edu.
authors.forename: J Scott
authors.initials: JS
authors.lastname: Kriegshauser
authors.affiliation: Department of Radiology, Mayo Clinic Hospital, 5777 E. Mayo Blvd., Phoenix, AZ 85054.
authors.forename: Maitray D
authors.initials: MD
authors.lastname: Patel
authors.affiliation: Department of Radiology, Mayo Clinic Hospital, 5777 E. Mayo Blvd., Phoenix, AZ 85054.
authors.forename: Scott W
authors.initials: SW
authors.lastname: Young
authors.affiliation: Department of Radiology, Mayo Clinic Hospital, 5777 E. Mayo Blvd., Phoenix, AZ 85054.
authors.forename: Frederick
authors.initials: F
authors.lastname: Chen
authors.affiliation: Department of Radiology, Mayo Clinic Hospital, 5777 E. Mayo Blvd., Phoenix, AZ 85054.
authors.forename: William G
authors.initials: WG
authors.lastname: Eversman
authors.affiliation: Department of Biostatistics, Mayo Clinic, Scottsdale, Arizona.
authors.forename: Yu-Hui H
authors.initials: YH
authors.lastname: Chang
mesh_terms: D015897:Comorbidity; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000009:adverse effects / Q000706:statistics & numerical data*; D005260:Female; D006470:Hemorrhage / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D006977:Hypertension, Renal / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D015994:Incidence; D007668:Kidney / Q000473:pathology*; D007674:Kidney Diseases / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018570:Risk Assessment; D016896:Treatment Outcome