title: Association of neutrophil-lymphocyte ratio with impaired aortic elasticity in newly diagnosed and never-treated hypertensive patients.
abstract: OBJECTIVE
  The aim of our study was to investigate the relationship between neutrophil-to-lymphocyte ratio (NLR) and aortic elasticity in patients with newly diagnosed essential hypertension (HT).
  
  
  METHODS
  A total of 101 patients with newly diagnosed and untreated essential HT and 54 healthy control patients were enrolled. Aortic stiffness (β) index, aortic strain and aortic distensibility (AoD) were measured with formulas by using transthoracic echocardiography and office blood pressure obtained by sphygmomanometer data. NLR was calculated using complete blood count.
  
  
  RESULTS
  Patients with HT had significantly higher NLR compared with the healthy control group (2.49±0.77 vs. 1.80±0.65, P<0.001). In addition, there were significant differences between the HT and healthy control groups in β index (12.7±7.35 vs. 6.97±3.3, P<0.001) and AoD (3.0±1.54 vs. 4.85±1.35, P<0.001). There was also a statistically significant correlation between NLR and β index (r=0.727, P<0.001) and AoD (r=-0.606, P<0.001) parameters in hypertensive patients.
  
  
  CONCLUSIONS
  Our results showed that in patients with newly diagnosed and untreated essential HT, increased NLR has been significantly linked to impaired aortic elastic properties.
authors.affiliation: aDepartment of Cardiology, Türkiye Yüksek İhtisas Education and Research Hospital bDepartment of Cardiology, Dışkapı Yıldırım Beyazıt Education and Research Hospital cDepartment of Cardiology, Gazi University Faculty of Medicine, Ankara, Turkey.
authors.forename: Çağr
authors.initials: Ç
authors.lastname: Yayla
authors.forename: Uğur
authors.initials: U
authors.lastname: Canpolat
authors.forename: Ahmet
authors.initials: A
authors.lastname: Akyel
authors.forename: Kadriye
authors.initials: K
authors.lastname: Gayretl Yayla
authors.forename: Mehmet K
authors.initials: MK
authors.lastname: Akboğa
authors.forename: Azmi
authors.initials: A
authors.lastname: Eyiol
authors.forename: Eser
authors.initials: E
authors.lastname: Açkgöz
authors.forename: Selçuk
authors.initials: S
authors.lastname: Özkan
authors.forename: Rdvan
authors.initials: R
authors.lastname: Yalçn
authors.forename: Nuri B
authors.initials: NB
authors.lastname: Boyac
mesh_terms: D000328:Adult; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000503:physiopathology*; D008211:Lymphocyte Cooperation; D008297:Male; D008875:Middle Aged; D059289:Vascular Stiffness