title: Microsporidial stromal keratitis masquerading as acute graft rejection.
abstract: OBJECTIVE
  To describe the clinical features, disease course, management, and visual outcome of stromal microsporidial keratitis involving the corneal graft in an immunocompetent patient.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  We report the case of a 21-year-old immunocompetent woman, who underwent penetrating keratoplasty for advanced keratoconus in her right eye and presented with features of acute graft rejection after 15 months. Standard treatment using topical and systemic steroids failed to reverse the graft rejection. A regraft was performed in that eye. Histopathology of the donor corneal button revealed microsporidiosis involving the deep stroma.
  
  
  CONCLUSIONS
  Microsporidiosis is rarely encountered in a corneal graft and masquerades as acute graft rejection. Histopathology could help in making a final diagnosis.
authors.affiliation: Aravind Eye Hospital, Madurai, India.
authors.forename: Sayali
authors.initials: S
authors.lastname: Pradhan
authors.forename: Jeena
authors.initials: J
authors.lastname: Mascarenhas
authors.forename: M
authors.initials: M
authors.lastname: Srinivasan
mesh_terms: D000208:Acute Disease; D003319:Corneal Stroma / Q000382:microbiology*; D003937:Diagnosis, Differential; D015821:Eye Infections, Fungal / Q000382:microbiology*; D005260:Female; D006084:Graft Rejection / Q000175:diagnosis; D006801:Humans; D007121:Immunocompetence; D007634:Keratitis / Q000382:microbiology*; D015948:Keratoplasty, Penetrating / Q000009:adverse effects; D016881:Microsporidiosis / Q000175:diagnosis*; D055815:Young Adult