title: Erythema nodosum leprosum on glans penis: unusual manifestation of common disease.
abstract: BACKGROUND
  Erythema nodosum leprosum (ENL) classically presents as tender evanescent skin nodules involving extremities, trunk, and face but may appear at any site. Mucosal involvement in ENL is uncommon, and its occurrence over glans is extremely rare.
  
  
  METHODS
  We describe two interesting cases of ENL involving the glans penis and prepuce with different presentations.
  
  
  RESULTS
  The first case had lepromatous leprosy with ENL with involvement of the glans penis in the form of a painful ulcer with necrotic slough. The second case had borderline lepromatous leprosy with ENL with involvement of glans in the form of a single painful nodule. Histopathology showed features of ENL, and Ziehl-Neelsen staining showed numerous acid fast bacilli.
  
  
  CONCLUSIONS
  We should be aware of genital involvement of ENL, which is a rare presentation and needs to be differentiated from other conditions requiring a different management approach.
authors.affiliation: Department of Dermatology and Venereology, All India Institute of Medical Science, New Delhi, India.
authors.forename: Sunil Kumar
authors.initials: SK
authors.lastname: Kothiwala
authors.affiliation: Department of Dermatology and Venereology, All India Institute of Medical Science, New Delhi, India.
authors.forename: Sujay
authors.initials: S
authors.lastname: Khandpur
authors.affiliation: Department of Pathology, All India Institute of Medical Science, New Delhi, India.
authors.forename: Manoj Kumar
authors.initials: MK
authors.lastname: Singh
authors.affiliation: Department of Pathology, All India Institute of Medical Science, New Delhi, India.
authors.forename: Prashant
authors.initials: P
authors.lastname: Durgapal
mesh_terms: D000328:Adult; D004359:Drug Therapy, Combination; D004893:Erythema Nodosum / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D015440:Leprosy, Lepromatous / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009166:Mycobacterium leprae / Q000302:isolation & purification*; D010409:Penile Diseases / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D010413:Penis / Q000473:pathology*; D018570:Risk Assessment; D012494:Sampling Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome