title: A new ellagic acid derivative from Polygonum runcinatum.
abstract: A new ellagic acid derivative, 3,3'-dimethylellagic acid-4'-O-(6″-galloyl)-β-D-glucoside, named runcinatside (5), together with four known compounds 3,3'-dimethylellagic acid (1), 3,3',4'-trimethylellagic acid (2), 3,3'-dimethylellagic acid-4'-O-β-D-glucoside (3) and 3-methylellagic acid-4'-O-α-L-rhamno-pyranoside (4), was isolated from the roots of Polygonum runcinatum Buch.-Ham. ex D.Don Var. sinense Hemsl and the structures of these compounds were established by spectroscopic methods and comparison with previously reported data. All compounds showed antioxidant activities in vitro and compound 5 possessed the highest activity.
authors.affiliation: a Department of Natural Medicinal Chemistry , China Pharmaceutical University , #24 Tongjiaxiang, Nanjing 210009 P.R. China.
authors.forename: Zhi-Hong
authors.initials: ZH
authors.lastname: Zhou
authors.forename: Min-Zhuo
authors.initials: MZ
authors.lastname: Liu
authors.forename: Meng-Hua
authors.initials: MH
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Qu
authors.forename: Jian-Bo
authors.initials: JB
authors.lastname: Sun
authors.forename: Jing-Yu
authors.initials: JY
authors.lastname: Liang
authors.forename: Fei-Hua
authors.initials: FH
authors.lastname: Wu
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D004610:Ellagic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D019664:Polygonaceae / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D005960:Glucosides; C000598477:runcinatside; D004610:Ellagic Acid
keywords: Polygonum runcinatum; antioxidant activity; chemical constituents; ellagic acid derivative