title: A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans.
abstract: A better understanding of the origin and natural reservoirs of resistance determinants is fundamental to efficiently tackle antibiotic resistance. This paper reports the identification of a novel 5.8 kb erythromycin resistance plasmid, from Bacillus sp. HS24 isolated from the marine sponge Haliclona simulans. pBHS24B has a mosaic structure and carries the erythromycin resistance gene erm(T). This is the first report of an erythromycin resistance plasmid from a sponge associated bacteria and of the Erm(T) determinant in the genus Bacillus.
authors.affiliation: School of Pharmacy, University College Cork, Cork, Ireland.
authors.forename: Teresa M
authors.initials: TM
authors.lastname: Barbosa
authors.affiliation: Department of Microbiology, University College Cork, Cork, Ireland; Biomerit Research Centre, University College Cork, Cork, Ireland.
authors.forename: Robert W
authors.initials: RW
authors.lastname: Phelan
authors.affiliation: Department of Microbiology, University College Cork, Cork, Ireland.
authors.forename: Dara
authors.initials: D
authors.lastname: Leong
authors.affiliation: Department of Microbiology, University College Cork, Cork, Ireland; Marine Biotechnology Centre, Environmental Research Institute, University College Cork, Cork, Ireland.
authors.forename: John P
authors.initials: JP
authors.lastname: Morrissey
authors.affiliation: Department of Microbiology, University College Cork, Cork, Ireland; Biomerit Research Centre, University College Cork, Cork, Ireland.
authors.forename: Claire
authors.initials: C
authors.lastname: Adams
authors.affiliation: Department of Microbiology, University College Cork, Cork, Ireland; Marine Biotechnology Centre, Environmental Research Institute, University College Cork, Cork, Ireland.
authors.forename: Alan D W
authors.initials: AD
authors.lastname: Dobson
authors.affiliation: Department of Microbiology, University College Cork, Cork, Ireland; Biomerit Research Centre, University College Cork, Cork, Ireland; Marine Biotechnology Centre, Environmental Research Institute, University College Cork, Cork, Ireland; Curtin University, School of Biomedical Sciences, Perth WA 6845, Australia.
authors.forename: Fergal
authors.initials: F
authors.lastname: O'Gara
mesh_terms: D000818:Animals; D059001:Aquatic Organisms / Q000382:microbiology*; D001407:Bacillus / Q000235:genetics*; D001483:Base Sequence; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D004917:Erythromycin; D008969:Molecular Sequence Data; D010957:Plasmids / Q000235:genetics*; D011161:Porifera / Q000382:microbiology*
chemical_list: D004917:Erythromycin