title: Monitored viral load: a measure of HIV treatment outcomes in an outpatient setting in Rhode Island.
abstract: Community viral load measurements have been postulated to be a population-based biomarker of HIV disease. We propose the use of the monitored community viral load (mCVL) as an aggregate measure of viral load among persons receiving HIV care with available HIV-1 plasma viral loads and applied it to our clinic population from 2003-2010. We demonstrated a reduction in mCVL from 16,589 copies/ml to 11,992 copies/ml that correlated with a rising rate of antiretroviral use and HIV viral suppression; however, differences among risk populations were observed. The mCVL is a useful measure of HIV burden among patients in-care; it may reflect the HIV transmission risk in the community and help target preventive interventions.
authors.affiliation: The Miriam Hospital, Providence RI.
authors.forename: Francine
authors.initials: F
authors.lastname: Touzard Romo
authors.affiliation: The Miriam Hospital, Providence RI; The Alpert Medical School of Brown University, Providence RI.
authors.forename: Fizza S
authors.initials: FS
authors.lastname: Gillani
authors.affiliation: The Miriam Hospital, Providence RI; The Alpert Medical School of Brown University, Providence RI.
authors.forename: Peter
authors.initials: P
authors.lastname: Ackerman
authors.affiliation: The Miriam Hospital, Providence RI; The Alpert Medical School of Brown University, Providence RI.
authors.forename: Aadia
authors.initials: A
authors.lastname: Rana
authors.affiliation: The Miriam Hospital, Providence RI; The Alpert Medical School of Brown University, Providence RI.
authors.forename: Erna M
authors.initials: EM
authors.lastname: Kojic
authors.affiliation: The Miriam Hospital, Providence RI; The Alpert Medical School of Brown University, Providence RI.
authors.forename: Curt G
authors.initials: CG
authors.lastname: Beckwith
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D017281:Cost of Illness; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012237:Rhode Island / Q000453:epidemiology; D012307:Risk Factors; D016896:Treatment Outcome; D019562:Viral Load / Q000379:methods / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents
keywords: Antiretroviral therapy; Community viral load; HIV; Rhode Island