title: Biological properties of ligand-dependent activation of the MET receptor kinase in acute myeloid leukemia.
authors.affiliation: 1] Department of Medicine, Mount Sinai St Luke's-Roosevelt Hospital Center, New York, NY, USA [2] Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, New York, NY, USA.
authors.forename: S F
authors.initials: SF
authors.lastname: McGee
authors.affiliation: Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
authors.forename: S M
authors.initials: SM
authors.lastname: Kornblau
authors.affiliation: Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Qiu
authors.affiliation: Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
authors.forename: A T
authors.initials: AT
authors.lastname: Look
authors.affiliation: Bioinformatics and Computational Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
authors.forename: N
authors.identifier: 0000000227288011
authors.initials: N
authors.lastname: Zhang
authors.affiliation: Bioinformatics and Computational Biology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
authors.forename: S-Y
authors.initials: SY
authors.lastname: Yoo
authors.affiliation: Departmentt of Biomedical Informatics, Ohio State University College of Medicine, Columbus, OH, USA.
authors.forename: K R
authors.initials: KR
authors.lastname: Coombes
authors.affiliation: 1] Molecular Pharmacology and Chemistry Program, Sloan Kettering Institute, New York, NY, USA [2] Department of Pediatrics, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, Cornell University, New York, NY, USA.
authors.forename: A
authors.identifier: 0000000280639191
authors.initials: A
authors.lastname: Kentsis
mesh_terms: D000465:Algorithms; D000970:Antineoplastic Agents / Q000494:pharmacology; D001667:Binding, Competitive; D000077547:Crizotinib; D015973:Gene Expression Regulation, Leukemic; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000378:metabolism*; D008024:Ligands; D008962:Models, Theoretical; D009154:Mutation; D010766:Phosphorylation; D040081:Protein Array Analysis; D011485:Protein Binding; D019859:Proto-Oncogene Proteins c-met / Q000378:metabolism*; D011720:Pyrazoles / Q000494:pharmacology; D011725:Pyridines / Q000494:pharmacology; D015398:Signal Transduction; D013816:Thermodynamics
chemical_list: D000970:Antineoplastic Agents; D008024:Ligands; D011720:Pyrazoles; D011725:Pyridines; D000077547:Crizotinib; C491743:MET protein, human; D019859:Proto-Oncogene Proteins c-met