title: [Analysis of real-world use different treatment shuxuetong injection effects on liver and kidney function].
abstract: OBJECTIVE
  To understand the real world, the use of ultra- treatment Shuxuetong injection on liver and kidney functions are affected.
  
  
  METHODS
  The 18 hospitals of the country's HIS data sources from which to choose to use Shuxuetong injection, between the ages of 18 to 80 years, using Shuxuetong and the first seven days after discontinuation of at least 7 days has once aspartate aminotransferase or alanine aminotransferase, or creatinine or blood urea nitrogen were measured value as a research object, the number of days of medication is based on more than 14 days, divided into treatment group and the normal course of super-group to reach the normal range of physical and chemical indicators 200% of the upper limit is defined as abnormal. Using the propensity score method, balance the known confounding factors, differences in the occurrence of abnormal renal function and compared between the two groups.
  
  
  RESULTS
  The treatment group and the normal course of super-group, resulting in alanine aminotransferase, aspartate aminotransferase, creatinine, urea nitrogen equally likely targets abnormal changes, no statistically significant difference.
  
  
  CONCLUSIONS
  Based on the available data did not find "super treatment using Shuxuetong damage the liver and kidney function" the situation, but the clinical disease lasts insist on the principle can not be arbitrarily extended treatment to prevent long-term medication.
authors.forename: Jun-jie
authors.initials: JJ
authors.lastname: Jiang
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.forename: Yan-ming
authors.initials: YM
authors.lastname: Xie
authors.forename: Hu
authors.initials: H
authors.lastname: Yang
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhuang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000410:Alanine Transaminase / Q000378:metabolism; D001219:Aspartate Aminotransferases / Q000378:metabolism; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal; C532053:shuxuetong; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase