title: Monitoring corneal hydration with a mid-infrared (IR) laser.
abstract: A mid-infrared (IR) source at ∼ 3 μm radiation is used as a probe to measure hydration in porcine cornea. Since the Er(3+):YAG emission targets vibrational modes (around 3300 cm(-1)) in the H2O molecule, it is highly sensitive to changes in water content in the first ∼ 10 μm of the corneal tissue.
authors.affiliation: Department of Electrical Engineering, University of California, Los Angeles, CA, USA. Electronic address: abhijeet@ucla.edu.
authors.forename: Abhijeet
authors.initials: A
authors.lastname: Joshi
authors.affiliation: Department of Bio-Medical Engineering, University of California, Los Angeles, CA, USA.
authors.forename: David B
authors.initials: DB
authors.lastname: Bennett
authors.affiliation: Department of Electrical Engineering, University of California, Los Angeles, CA, USA.
authors.forename: Oscar M
authors.initials: OM
authors.lastname: Stafsudd
mesh_terms: D000818:Animals; D001834:Body Water / Q000378:metabolism*; D003315:Cornea / Q000737:chemistry*; D003316:Corneal Diseases / Q000175:diagnosis / Q000378:metabolism*; D004195:Disease Models, Animal; D007259:Infrared Rays; D007834:Lasers; D008991:Monitoring, Physiologic / Q000379:methods*; D013552:Swine
keywords: corneal hydration; hydration monitoring; mid-IR probe beam; terahertz imaging