title: Relationship between clinical signs and results of impulse oscillometry in pigs originating from the field.
abstract: The aim of the present study was to assess the contribution of clinical data to the variability of impulse oscillometric test results observed previously by Püllen et al. (2014). Fifty-eight German hybrid pigs from 29 different herds with unknown respiratory status were examined in the context of routine diagnostics as part of herd health service. Routine clinical examination was extended to a total set of 29 parameters, representing detailed clinical signs of the respiratory system, and to lung function testing applying the impulse oscillometry system (IOS). The resulting linear relationship between clinical data and variables of pulmonary mechanics had a mean r(2) of 0.52. Clinical parameters predominantly representing the lower respiratory tract closely correlated with established impulse oscillometric indices reflecting peripheral airways. Because of a restricted relationship between pulmonary functional disorders and clinical data, additional diagnostic methods are required to reveal the proportion of variance undefined by clinical examination.
authors.affiliation: Department for Veterinary Clinical Sciences, Justus-Liebig-University Giessen, Frankfurter Strasse 112, Giessen, Germany. Electronic address: cilia.kronenberg@gmx.de.
authors.forename: C
authors.initials: C
authors.lastname: Püllen
authors.affiliation: Department for Veterinary Clinical Sciences, Justus-Liebig-University Giessen, Frankfurter Strasse 112, Giessen, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Becker
authors.affiliation: Institute of Molecular Pathogenesis at the Friedrich-Loeffler-Institut (Federal Research Institute for Animal Health), Naumburger Str. 96a, Jena, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Reinhold
authors.affiliation: CareFusion Germany 234 GmbH, Leibnizstrasse 7, Hoechberg, Germany.
authors.forename: H-J
authors.initials: HJ
authors.lastname: Smith
authors.affiliation: Department for Veterinary Clinical Sciences, Justus-Liebig-University Giessen, Frankfurter Strasse 112, Giessen, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Reiner
mesh_terms: D000818:Animals; D009991:Oscillometry / Q000662:veterinary*; D015203:Reproducibility of Results; D012129:Respiratory Function Tests / Q000662:veterinary; D012140:Respiratory Tract Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis / Q000503:physiopathology*
keywords: Clinical examination; Impulse oscillometry; Pigs; Reactance area; Respiratory disease