title: Maturation of mismatch negativity and P3a response across adolescence.
abstract: Adolescents experience significant changes in various physiological and psychological domains due to changes in their brain's structure and function. A lot is known about structural changes in the brain across adolescence. However, less research has investigated changes in brain function during this period. In this study, we tracked the maturation of the auditory mismatch negativity (MMN) and P3a brain responses - both posited as neural indices of auditory discrimination - in 90 adolescents aged 10-18 years. We found that P3a mean amplitude and latency decreased significantly across adolescence, but there was no reliable change in the MMN. These results suggest that neural processes associated with passive auditory processing continue to develop well into adolescence.
authors.affiliation: The MARCS Institute, University of Western Sydney, Locked Bag 1797, Penrith, Sydney, NSW 2751, Australia; ARC Centre of Excellence in Cognition and its Disorders, Department of Cognitive Science, Macquarie University, Sydney, Australia. Electronic address: y.mahajan@uws.edu.au.
authors.forename: Yatin
authors.initials: Y
authors.lastname: Mahajan
authors.affiliation: ARC Centre of Excellence in Cognition and its Disorders, Department of Cognitive Science, Macquarie University, Sydney, Australia.
authors.forename: Genevieve
authors.initials: G
authors.lastname: McArthur
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001307:Auditory Perception; D001921:Brain / Q000502:physiology*; D002648:Child; D018913:Event-Related Potentials, P300; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D008297:Male; D055815:Young Adult
keywords: Adolescence; Maturation; Mismatch negativity; P3a