title: [Explore ideal of establishing ischemic stroke drugs group modules based on electronic medical records].
abstract: Ischemic stroke is a kind of common and frequently-occurring disease in clinic. It has high morbidity and high mortality and high morbidity characteristics. It was treated may also use a variety of Chinese and western medicine in the acute phase in the large general hospital in clinical practice. According to the "modularity theory" from biology, different patients using different drugs, and with combination of drugs for the treatment of this disease may have a variety of topological structure characteristics. This study proposed in the national 15 large general hospital electronic medical records of database, the complex network constructed by acute ischemic stroke disease using drugs, adopting to the complex network analysis and data mining methods to build for different ischemic stroke patients who are many of Chinese and western medicine group modules. These modules can be explained structure and function characteristics, and to explore the appropriate crowd and evaluate drug group module efficacy and safety in use in clinic. It provide direction to optimize the clinical treatment for ischemic stroke, provide new method for the research on combination, also provide the basis for drug combination of Chinese and western solution into the guide.
authors.forename: Wei
authors.initials: W
authors.lastname: Yang
authors.forename: Yan-ming
authors.initials: YM
authors.lastname: Xie
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D057225:Data Mining; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D057286:Electronic Health Records; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020521:Stroke / Q000188:drug therapy*
chemical_list: D004365:Drugs, Chinese Herbal