title: Scabies.
abstract: BACKGROUND
  Scabies is a common public health problem. In many resource-poor settings, scabies is an endemic problem; whereas in industrialised countries, it is most common in institutionalised communities.
  
  
  METHODS
  We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of topical treatments for scabies? What are the effects of systemic treatments for scabies? We searched: Medline, Embase, The Cochrane Library, and other important databases up to July 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
  
  
  RESULTS
  We found five studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
  
  
  CONCLUSIONS
  In this systematic review, we present information relating to the effectiveness and safety of the following interventions: benzyl benzoate (topical), crotamiton (topical), ivermectin (oral), malathion (topical), permethrin (topical), and sulfur compounds (topical).
authors.affiliation: Blenheim House, Leeds, UK.
authors.forename: Paul
authors.initials: P
authors.lastname: Johnstone
authors.forename: Mark
authors.initials: M
authors.lastname: Strong
mesh_terms: D000977:Antiparasitic Agents / Q000627:therapeutic use*; D006801:Humans; D012532:Scabies / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000977:Antiparasitic Agents