title: Pituitary MRI characteristics in 297 acromegaly patients based on T2-weighted sequences.
abstract: Responses of GH-secreting adenomas to multimodal management of acromegaly vary widely between patients. Understanding the behavioral patterns of GH-secreting adenomas by identifying factors predictive of their evolution is a research priority. The aim of this study was to clarify the relationship between the T2-weighted adenoma signal on diagnostic magnetic resonance imaging (MRI) in acromegaly and clinical and biological features at diagnosis. An international, multicenter, retrospective analysis was performed using a large population of 297 acromegalic patients recently diagnosed with available diagnostic MRI evaluations. The study was conducted at ten endocrine tertiary referral centers. Clinical and biochemical characteristics, and MRI signal findings were evaluated. T2-hypointense adenomas represented 52.9% of the series, were smaller than their T2-hyperintense and isointense counterparts (P<0.0001), were associated with higher IGF1 levels (P=0.0001), invaded the cavernous sinus less frequently (P=0.0002), and rarely caused optic chiasm compression (P<0.0001). Acromegalic men tended to be younger at diagnosis than women (P=0.067) and presented higher IGF1 values (P=0.01). Although in total, adenomas had a predominantly inferior extension in 45.8% of cases, in men this was more frequent (P<0.0001), whereas in women optic chiasm compression of macroadenomas occurred more often (P=0.0067). Most adenomas (45.1%) measured between 11 and 20 mm in maximal diameter and bigger adenomas were diagnosed at younger ages (P=0.0001). The T2-weighted signal differentiates GH-secreting adenomas into subgroups with particular behaviors. This raises the question of whether the T2-weighted signal could represent a factor in the classification of acromegalic patients in future studies.
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Iulia
authors.initials: I
authors.lastname: Potorac
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Petrossians
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Adrian F
authors.initials: AF
authors.lastname: Daly
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Franck
authors.initials: F
authors.lastname: Schillo
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Claude
authors.initials: C
authors.lastname: Ben Slama
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Sonia
authors.initials: S
authors.lastname: Nagi
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Mouna
authors.initials: M
authors.lastname: Sahnoun
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Brue
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Nadine
authors.initials: N
authors.lastname: Girard
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Chanson
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Ghaidaa
authors.initials: G
authors.lastname: Nasser
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Caron
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Fabrice
authors.initials: F
authors.lastname: Bonneville
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Gérald
authors.initials: G
authors.lastname: Raverot
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Lapras
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: François
authors.initials: F
authors.lastname: Cotton
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Brigitte
authors.initials: B
authors.lastname: Delemer
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Brigitte
authors.initials: B
authors.lastname: Higel
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Boulin
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Stéphan
authors.initials: S
authors.lastname: Gaillard
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Florina
authors.initials: F
authors.lastname: Luca
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Bernard
authors.initials: B
authors.lastname: Goichot
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Dietemann
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France albert.beckers@chu.ulg.ac.be.
authors.forename: Albert
authors.initials: A
authors.lastname: Beckers
authors.affiliation: Department of EndocrinologyCentre Hospitalier Universitaire de Liège, Université de Liège, Domaine Universitaire du Sart Tilman, 4000 Liège, BelgiumDepartment of EndocrinologyCHU Besançon, Besançon, FranceDepartments of EndocrinologyNeuroradiologySchool of Medicine, Tunis University, Tunis, TunisiaDepartments of EndocrinologyNeuroradiologyCHU Marseille, Marseille, FranceDepartments of EndocrinologyNeuroradiologyCHU Bicêtre, Le Kremlin-Bicêtre, FranceDepartments of EndocrinologyNeuroradiologyCHU Toulouse, Toulouse, FranceDepartments of EndocrinologyRadiologyHospices Civils de Lyon, Lyon, FranceDepartments of EndocrinologyNeuroradiologyCHU Reims, Reims, FranceDepartments of NeuroradiologyNeurosurgeryCH Foch, Suresnes, FranceDepartments of EndocrinologyNeuroradiologyCHU Strasbourg, Strasbourg, France.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Bonneville
mesh_terms: D000172:Acromegaly / Q000378:metabolism / Q000473:pathology*; D000236:Adenoma / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D000328:Adult; D005260:Female; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010902:Pituitary Gland / Q000378:metabolism / Q000473:pathology*
chemical_list: D013006:Growth Hormone
keywords: MRI; T2-weighted signal; acromegaly; pituitary adenoma