title: [Multiple special formed titanium mesh cages in the treatment of lumbo-sacral spinal tuberculosis via posterior approach only].
abstract: OBJECTIVE
  To determine the clinical efficacy and feasibility of multiple special formed titanium mesh cages (TMCs) to treat lumbo-sacral spinal tuberculosis via posterior approach.
  
  
  METHODS
  From July, 2007 to June, 2013, 25 patients with lumbo-sacral spinal tuberculosis underwent one-stage posterior debridement, internal fi xation, and interbody fusion using multiple special formed titanium meshes. We compared the parameters as follow: the pre- and post-operative American Spinal Injury Association (ASIA) score, lumbo-sacral angle, the height of intervertebral space, visual analogue scale (VAS), and erythrocyte sedimentation rate (ESR), and observed operation time, intraoperative blood loss, and time of bone graft fusion.
  
  
  RESULTS
  Operation time ranged from 90 to 180 min, (128±24) min in average. Blood loss in the operation ranged from 100 to 800 mL, (310±125) mL in average. The patients were followed up for 24 to 59 months, (43±7) months in average. One patient delayed healing of wound. ASIA score was improved in a certain degree in patients with neurological dysfunctions. The lumbo-sacral angle and the height of intervertebral space in the post-operation were significantly higher than those in the preoperation (P< 0.001). VAS was reduced obviously after 2 weeks of operation. The ESR recovered to the normal level 6 months after operation in all the patients. Solid fusion was achieved within 4 to 8 months, 6 months in average. No sinus tract, cerebrospinal meningitis, tuberculosis recurrence and titanium mesh subsidence were found.
  
  
  CONCLUSIONS
  For lumbo-sacral tuberculosis, multiple special formed titanium mesh cages via posterior approach is safe and effective, which is good to the stability in spine reconstruction.
authors.affiliation: Department of Spianl Cord, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Abudunaibi
authors.initials: A
authors.lastname: Aili
authors.forename: Hongqi
authors.initials: H
authors.lastname: Zhang
authors.forename: Mingxing
authors.initials: M
authors.lastname: Tang
authors.forename: Chaofeng
authors.initials: C
authors.lastname: Guo
authors.forename: Yuxiang
authors.initials: Y
authors.lastname: Wang
authors.forename: Jianhuang
authors.initials: J
authors.lastname: Wu
authors.forename: Jinyang
authors.initials: J
authors.lastname: Liu
mesh_terms: D016063:Blood Loss, Surgical; D016025:Bone Transplantation; D003646:Debridement; D006801:Humans; D008161:Lumbosacral Region / Q000601:surgery*; D019637:Orthopedic Procedures; D011184:Postoperative Period; D019736:Prostheses and Implants; D019651:Plastic Surgery Procedures; D013123:Spinal Fusion; D013131:Spine; D013526:Surgical Mesh; D014025:Titanium; D014399:Tuberculosis, Spinal / Q000601:surgery*
chemical_list: D014025:Titanium