title: Impact of gender difference in hospital outcomes following percutaneous coronary intervention. Results of the Belgian Working Group on Interventional Cardiology (BWGIC) registry.
abstract: OBJECTIVE
  To determine whether there are gender-based differences in in-hospital outcomes among patients undergoing percutaneous coronary intervention (PCI).
  
  
  RESULTS
  We studied a large cohort using clinical data from a registry of 130,985 PCI procedures in Belgium, from January 2006 to February 2011. Compared to males, females were significantly older (70.3 vs. 64.8 years), and were more frequently diabetic or hypertensive. Men smoked more and more frequently had previous myocardial infarction (MI), previous PCI or previous coronary artery bypass graft (CABG) surgery. Coronary artery disease (CAD) was less severe in women, and PCI to the left anterior descending artery was more common in female patients. Unadjusted in-hospital mortality rates were higher in females versus males (2.5% for women and 1.6% for men, p<0.0001). After multivariable analysis, female gender remained an independent predictor of mortality (odds ratio 1.35, 95% CI: 1.22-1.49, p<0.0001).
  
  
  CONCLUSIONS
  Gender-based differences in hospital mortality rates after PCI were observed in this large registry. Female sex remained an independent predictor of mortality after multivariable adjustment.
authors.affiliation: University Hospital of Liege, Liege, Belgium.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Lempereur
authors.forename: Julien
authors.initials: J
authors.lastname: Magne
authors.forename: Kristoff
authors.initials: K
authors.lastname: Cornelis
authors.forename: Claude
authors.initials: C
authors.lastname: Hanet
authors.forename: Yves
authors.initials: Y
authors.lastname: Taeymans
authors.forename: Mathias
authors.initials: M
authors.lastname: Vrolix
authors.forename: Victor
authors.initials: V
authors.lastname: Legrand
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001530:Belgium; D003324:Coronary Artery Disease / Q000401:mortality* / Q000628:therapy*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects; D012042:Registries; D018570:Risk Assessment; D012307:Risk Factors; D012727:Sex Characteristics; D016896:Treatment Outcome