title: Open access integrated therapeutic and diagnostic platforms for personalized cardiovascular medicine.
abstract: It is undeniable that the increasing costs in healthcare are a concern. Although technological advancements have been made in healthcare systems, the return on investment made by governments and payers has been poor. The current model of care is unsustainable and is due for an upgrade. In developed nations, a law of diminishing returns has been noted in population health standards, whilst in the developing world, westernized chronic illnesses, such as diabetes and cardiovascular disease have become emerging problems. The reasons for these trends are complex, multifactorial and not easily reversed. Personalized medicine has the potential to have a significant impact on these issues, but for it to be truly successful, interdisciplinary mass collaboration is required. We propose here a vision for open-access advanced analytics for personalized cardiac diagnostics using imaging, electrocardiography and genomics.
authors.affiliation: Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. patrickg@theranosticslab.com.
authors.forename: Patrick A
authors.initials: PA
authors.lastname: Gladding
authors.affiliation: Waitemata District Health Board, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. andrew.cave@waitematadhb.govt.nz.
authors.forename: Andrew
authors.initials: A
authors.lastname: Cave
authors.affiliation: Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. andrew.cave@waitematadhb.govt.nz.
authors.forename: Mehran
authors.initials: M
authors.lastname: Zareian
authors.affiliation: Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. andrew.cave@waitematadhb.govt.nz.
authors.forename: Kevin
authors.initials: K
authors.lastname: Smith
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. r.jagir@auckland.ac.nz.
authors.forename: Jagir
authors.initials: J
authors.lastname: Hussan
authors.affiliation: Auckland Bioengineering Institute, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. p.hunter@auckland.ac.nz.
authors.forename: Peter
authors.initials: P
authors.lastname: Hunter
authors.affiliation: Institute for Lasers, Photonics and Biophotonics, 428 Natural Science Complex, University at Buffalo, NY 14260-3000, USA. erogbogbo@gmail.com.
authors.forename: Folarin
authors.initials: F
authors.lastname: Erogbogbo
authors.affiliation: Ocean NanoTech, 2143 Worth Lane, Springdale, AR 72764, USA. zapaguilar@yahoo.com.
authors.forename: Zoraida
authors.initials: Z
authors.lastname: Aguilar
authors.affiliation: Wyle Science, Technology and Engineering Group, 1200 Hercules, Houston, TX 77058, USA. david.s.martin@nasa.gov.
authors.forename: David S
authors.initials: DS
authors.lastname: Martin
authors.affiliation: DNA Medicine Institute, 727 Massachusetts Avenue, Cambridge, MA 02139, USA. echan@dnamedinstitute.com.
authors.forename: Eugene
authors.initials: E
authors.lastname: Chan
authors.affiliation: Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr, Pasadena, CA 91109, USA. margie.l.homer@jpl.nasa.gov.
authors.forename: Margie L
authors.initials: ML
authors.lastname: Homer
authors.affiliation: Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr, Pasadena, CA 91109, USA. abhijit.v.shevade@jpl.nasa.gov.
authors.forename: Abhijit V
authors.initials: AV
authors.lastname: Shevade
authors.affiliation: NASA Glenn Research Center, 21000 Brookpark Rd, Cleveland, OH 44135, USA. mohammad.kassemi@nasa.gov.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Kassemi
authors.affiliation: Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. thomasj@ccf.org.
authors.forename: James D
authors.initials: JD
authors.lastname: Thomas
authors.affiliation: Theranostics Laboratory Ltd, North Shore Hospital, Private Bag 93503, Auckland 0622, New Zealand. ttschlegel@gmail.com.
authors.forename: Todd T
authors.initials: TT
authors.lastname: Schlegel