title: Catalytic divergent synthesis of 3H or 1H pyrroles by [3 + 2] cyclization of allenoates with activated isocyanides.
abstract: The cyclization of allenoates with activated isocyanides was reported for the first time. While Ag catalysis led to an unprecedented enantioselective synthesis of 3H pyrroles, a simple procedure using PPh3 produced a wide range of polysubstituted 1H pyrroles with high efficiency.
authors.affiliation: Department of Chemistry, National University of Singapore , 3 Science Drive 3, Singapore, Republic of Singapore , 117543.
authors.forename: Jia-Yu
authors.initials: JY
authors.lastname: Liao
authors.forename: Pan-Lin
authors.initials: PL
authors.lastname: Shao
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D003486:Cyanides / Q000737:chemistry*; D003500:Cyclization; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D000475:Alkenes; D003486:Cyanides; D011758:Pyrroles