title: Applications of FT-IR spectrophotometry in cancer diagnostics.
abstract: This review provides a brief background to the application of infrared spectroscopy, including Fourier transform-infrared spectroscopy, in biological fluids. It is not meant to be complete or exhaustive but to provide the reader with sufficient background for selected applications in cancer diagnostics. Fourier transform-infrared spectroscopy (FT-IR) is a fast and nondestructive analytical method. The infrared spectrum of a mixture serves as the basis to quantitate its constituents, and a number of common clinical chemistry tests have proven to be feasible using this approach. This review focuses on biomedical FT-IR applications, published in the period 2009-2013, used for early detection of cancer through qualitative and quantitative analysis.
authors.affiliation: a SCIENT - Research Center for Instrumental Analysis (by S.C. CROMATEC_PLUS S.R.L.) , Bucharest , Romania.
authors.forename: Andrei A
authors.initials: AA
authors.lastname: Bunaciu
authors.forename: Vu Dang
authors.initials: VD
authors.lastname: Hoang
authors.forename: Hassan Y
authors.initials: HY
authors.lastname: Aboul-Enein
mesh_terms: D055088:Early Detection of Cancer / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis*; D013053:Spectrophotometry / Q000379:methods*; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods*
keywords: FT-IR spectroscopy; biomedical analysis; clinical diagnosis; early detection of cancer