title: The role of hypoxia at primary dysmenorrhea, utilizing a novel hypoxia marker--SCUBE1.
abstract: OBJECTIVE
  To determine the SCUBE1 levels in adolescents with primary dysmenorrhea.
  
  
  METHODS
  A prospective cross-sectional study.
  
  
  METHODS
  A university hospital outpatient clinic, Rize, Turkey.
  
  
  METHODS
  A total of 40 adolescent girls, 15 on menses and 25 not on menses.
  
  
  METHODS
  Demographic features and menstrual history of the participants were assessed and blood samples were obtained for detecting the platelet volume, platelet counts, and SCUBE1 levels of the participants.
  
  
  RESULTS
  No difference was detected between the 2 groups in mean platelet volume, platelet count, and SCUBE1 levels.
  
  
  CONCLUSIONS
  Future trials are required to investigate the relation between SCUBE1 levels and primary dysmenorrhea.
authors.affiliation: Department of Gynecology and Obstetrics, Recep Tayyip Erdoğan University, Faculty of Medicine, Rize, Turkey. Electronic address: yesimbay@yahoo.com.
authors.forename: Yeşim Bayoğlu
authors.initials: YB
authors.lastname: Tekin
authors.affiliation: Department of Gynecology and Obstetrics, Recep Tayyip Erdoğan University, Faculty of Medicine, Rize, Turkey.
authors.forename: Emine Seda
authors.initials: ES
authors.lastname: Güvendağ Güven
authors.affiliation: Department of Biochemistry, Recep Tayyip Erdoğan University, Faculty of Medicine, Rize, Turkey.
authors.forename: Aynur
authors.initials: A
authors.lastname: Kirbas
authors.affiliation: Department of Gynecology and Obstetrics, Recep Tayyip Erdoğan University, Faculty of Medicine, Rize, Turkey.
authors.forename: Işık
authors.initials: I
authors.lastname: Üstüner
authors.affiliation: Department of Gynecology and Obstetrics, Recep Tayyip Erdoğan University, Faculty of Medicine, Rize, Turkey.
authors.forename: Osman Deniz
authors.initials: OD
authors.lastname: Doğan
authors.affiliation: Department of Gynecology and Obstetrics, Recep Tayyip Erdoğan University, Faculty of Medicine, Rize, Turkey.
authors.forename: Gülşah
authors.initials: G
authors.lastname: Balik
authors.affiliation: Department of Gynecology and Obstetrics, Recep Tayyip Erdoğan University, Faculty of Medicine, Rize, Turkey.
authors.forename: Figen Kir
authors.initials: FK
authors.lastname: Şahin
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D002135:Calcium-Binding Proteins; D003430:Cross-Sectional Studies; D004412:Dysmenorrhea / Q000097:blood* / Q000209:etiology; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000097:blood* / Q000150:complications; D008565:Membrane Proteins / Q000097:blood*; D010976:Platelet Count; D011446:Prospective Studies; D014421:Turkey
chemical_list: D015415:Biomarkers; D002135:Calcium-Binding Proteins; D008565:Membrane Proteins; C469998:SCUBE1 protein, human
keywords: Hypoxia; Primary dysmenorrhea; SCUBE1; adolescent