title: Fluorothymidine PET/CT in neurolymphomatosis.
abstract: Neurolymphomatosis, a rare extranodal lymphoma, may involve the cranial nerves, peripheral nerves, spinal nerve roots, or nerve plexus. F-FDG PET/CT however shows increased FDG uptake in the nerves but is not specific for malignancy. We report a patient with neurolymphomatosis who underwent F-FDG PET/CT and F-fluorothymidine PET/CT where both the scans showed increased tracer uptake in the right sciatic nerve, proven later as neurolymphomatosis on nerve biopsy. Furthermore, the F-FDG avid mediastinal lymph nodes did not show F-fluorothymidine avidity, suggesting an inflammatory etiology.
authors.affiliation: From the Departments of *Nuclear Medicine and PET and †Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Chinmoy Kumar
authors.initials: CK
authors.lastname: Biswal
authors.forename: Bhagwant Rai
authors.initials: BR
authors.lastname: Mittal
authors.forename: Jaya
authors.initials: J
authors.lastname: Shukla
authors.forename: Rakhee
authors.initials: R
authors.lastname: Vatsa
authors.forename: Anish
authors.initials: A
authors.lastname: Bhattacharya
authors.forename: Sudesh
authors.initials: S
authors.lastname: Prabhakar
mesh_terms: D000818:Animals; D001706:Biopsy; D015224:Dideoxynucleosides; D019788:Fluorodeoxyglucose F18; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000473:pathology*; D008297:Male; D008380:Marek Disease / Q000000981:diagnostic imaging*; D008875:Middle Aged; D064847:Multimodal Imaging; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D020426:Sciatic Neuropathy / Q000175:diagnosis* / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D015224:Dideoxynucleosides; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; C002854:alovudine