title: A combined administration of Aragvādādi kaṣāyam and Syrup Talekt induced skin rashes.
abstract: It is a common notion among people in India that herbal or Ayurvedic products are safe and do not produce any adverse effect. This is not true since Ayurveda has evaded many adverse effects which occur by combination of herbs. This axiom is potentiated by our report that occurs in the form of skin rashes. A 20-year-old South Indian female of Pittakapha prakṛti (constitution) after beginning therapy with Aragvādādi kaṣāyam (ARK) (poly-herbal formulation) and Syrup Talekt (poly-herbal patent formulation) for the treatment of recurrent incidence of abscess. Rash disappeared after stopping the suspected drug and treatment with Vibhītakī kaṣāyam (decoction of Terminilia bellarica) and Śatadhauta ghṛtam. Possible and probable (score 6) were the causality according to WHO-Uppsala Monitoring Centre and Naranjo's Adverse Drug Reaction Probability Scale and grouped under type-B reaction. To the best of our knowledge, this is the first case of skin rashes which seen after administration of ARK and Syrup Talekt. This report highlights the need of implementation of pharmacovigilance center in the hospital level and additional research in the field of skin toxicity of ARK and Syrup Talekt.
authors.affiliation: Department of Dravyaguna and Medical Research Center, Rajiv Gandhi Education Society's Ayurveda Medical College and PG Research Centre, Ron, India.
authors.forename: Manjunath
authors.initials: M
authors.lastname: Ajanal
authors.affiliation: Department of Panchakarma, KLEU Shri BMK Ayurved Mahavidhyalaya, Belgaum, Karnataka, India.
authors.forename: B S
authors.initials: BS
authors.lastname: Prasad
keywords: Abscess; Aragwadadi kashaya; Ayurveda; Talekt; skin rashes