title: Bochum ultrasound score allows distinction of chronic inflammatory from multifocal acquired demyelinating polyneuropathies.
abstract: OBJECTIVE
  The aim of this observational study was to evaluate the applicability of a recently introduced ultrasound score (Bochum ultrasound score; BUS) in distinguishing the chronic inflammatory demyelinating polyneuropathy (CIDP) from the multifocal motor neuropathy (MMN) or the multifocal acquired demyelinating sensory and motor neuropathy (MADSAM).
  
  
  METHODS
  The BUS underwent prospective evaluation of its applicability in a group of 13 patients (mean age 47.2, SD ± 13.7, 9 women), who were referred to our department between January 2012 and August 2013 with the clinical picture of a chronic symmetrical or asymmetrical sensory/sensorimotor neuropathy.
  
  
  RESULTS
  The cut-off value of ≥ 2 points in the "Bochum ultrasound score" showed a sensitivity of 80% and specificity of 87.5% (PPV=80%, NPV=87.5%) in distinguishing CIDP from MMN or MADSAM.
  
  
  CONCLUSIONS
  The BUS seems to allow a reliable distinction of CIDP from multifocal acquired demyelinating polyneuropathies causing predominantly motor nerve dysfunction, such as MMN or MADSAM. Our ultrasound findings indicate a stronger relationship of MADSAM to MMN, than to CIDP.
authors.affiliation: Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Germany. Electronic address: antonis.kerasnoudis@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Kerasnoudis
authors.affiliation: Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Germany. Electronic address: kalliapit@yahoo.gr.
authors.forename: K
authors.initials: K
authors.lastname: Pitarokoili
authors.affiliation: Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Germany. Electronic address: Ralf.Gold@ruhr-uni-bochum.de.
authors.forename: R
authors.initials: R
authors.lastname: Gold
authors.affiliation: Department of Neurology, St. Josef Hospital, Ruhr-University of Bochum, Germany. Electronic address: min-suk.yoon@uni-due.de.
authors.forename: M-S
authors.initials: MS
authors.lastname: Yoon
mesh_terms: D000328:Adult; D003711:Demyelinating Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004311:Double-Blind Method; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons; D009431:Neural Conduction / Q000502:physiology*; D011115:Polyneuropathies / Q000000981:diagnostic imaging* / Q000503:physiopathology; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011826:Radial Nerve / Q000000981:diagnostic imaging / Q000503:physiopathology; D012680:Sensitivity and Specificity; D013127:Spinal Nerves / Q000000981:diagnostic imaging* / Q000503:physiopathology; D013497:Sural Nerve / Q000000981:diagnostic imaging / Q000503:physiopathology; D014459:Ulnar Nerve / Q000000981:diagnostic imaging / Q000503:physiopathology; D014463:Ultrasonography
keywords: Bochum ultrasound score; Chronic inflammatory demyelinating polyneuropathy; Multifocal acquired demyelinating sensory and motor neuropathy; Multifocal motor neuropathy; Nerve ultrasound; Polyneuropathies