title: Malignant Bowel Obstruction in Patients With Recurrent Ovarian Cancer.
abstract: We sought to report incidence, risk factors, and survival related to bowel obstruction in 311 ovarian cancer patients with recurrent disease. A total of 68 (22%) had a documented bowel obstruction during their cancer course, and 49 (16%) developed it after cancer recurrence. Surprisingly, 142 (45%) fit into an "unknown" category (3+ months of data lacking from last contact/death). No risk factors were identified; management included surgery (n = 21), conservative measures (n = 21), and other (n = 7). Documented bowel obstruction was not associated with a statistically significant reduction in survival after cancer recurrence. In conclusion, although bowel obstruction occurs in only a subgroup of patients with ovarian cancer and does not appear to detract from survival after cancer recurrence, limited end-of-life information may be resulting in an underestimation of incidence.
authors.affiliation: Department of Medicine, Mayo Clinic, Rochester, MN, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Tran
authors.affiliation: Department of Medicine, Mayo Clinic, Rochester, MN, USA.
authors.forename: Clayton
authors.initials: C
authors.lastname: Spiceland
authors.affiliation: Department of Medicine, Mayo Clinic, Rochester, MN, USA.
authors.forename: Nicole P
authors.initials: NP
authors.lastname: Sandhu
authors.affiliation: Department of Oncology, Mayo Clinic, Rochester, MN, USA jatoi.aminah@mayo.edu.
authors.forename: Aminah
authors.initials: A
authors.lastname: Jatoi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D007415:Intestinal Obstruction / Q000209:etiology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000150:complications* / Q000401:mortality* / Q000473:pathology; D010166:Palliative Care / Q000379:methods; D011379:Prognosis; D012307:Risk Factors; D055815:Young Adult
keywords: bowel obstruction; end of life; morbidity; ovarian cancer