title: A Pregnant Woman Who Underwent Laparoscopic Adrenalectomy due to Cushing's Syndrome.
abstract: Cushing's syndrome (CS) may lead to severe maternal and fetal morbidities and even mortalities in pregnancy. However, pregnancy complicates the diagnosis and treatment of CS. This study describes a 26-year-old pregnant woman admitted with hypertension-induced headache. Hormonal analyses performed due to her cushingoid phenotype revealed a diagnosis of adrenocorticotropic hormone- (ACTH-) independent CS. MRI showed a 3.5 cm adenoma in her right adrenal gland. After preoperative metyrapone therapy, she underwent a successful unilateral laparoscopic adrenalectomy at 14-week gestation. Although she had a temporary postoperative adrenal insufficiency, hormonal analyses showed that she has been in remission since delivery. Findings in this patient, as well as those in previous patients, indicate that pregnancy is not an absolute contraindication for laparoscopic adrenalectomy. Rather, such surgery should be considered a safe and efficient treatment method for pregnant women with cortisol-secreting adrenal adenomas.
authors.affiliation: Division of Endocrinology, Erciyes University Medical School, 38039 Kayseri, Turkey.
authors.forename: Halit
authors.identifier: 0000-0003-2519-5978
authors.initials: H
authors.lastname: Diri
authors.affiliation: Division of Endocrinology, Erciyes University Medical School, 38039 Kayseri, Turkey.
authors.forename: Fahri
authors.initials: F
authors.lastname: Bayram
authors.affiliation: Division of Endocrinology, Erciyes University Medical School, 38039 Kayseri, Turkey.
authors.forename: Yasin
authors.initials: Y
authors.lastname: Simsek
authors.affiliation: Division of Endocrinology, Firat University Medical School, 23000 Elazığ, Turkey.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Ozkan
authors.affiliation: Department of General Surgery, Erciyes University Medical School, 38039 Kayseri, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Akcan
authors.affiliation: Department of Radiology, Erciyes University Medical School, 38039 Kayseri, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Karahan
authors.affiliation: Department of Internal Diseases, Erciyes University Medical School, 38039 Kayseri, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Ileri
authors.affiliation: Division of Endocrinology, Erciyes University Medical School, 38039 Kayseri, Turkey.
authors.forename: Sulbiye
authors.initials: S
authors.lastname: Aribas
authors.affiliation: Division of Endocrinology, Erciyes University Medical School, 38039 Kayseri, Turkey.
authors.forename: Mehmet Sait
authors.initials: MS
authors.lastname: Koc