title: General last-step labeling of biomolecule-based substrates by [12C], [13C], and [11C] carbon monoxide.
abstract: Alkaloid-, steroid-, biotin-, carbohydrate-, nucleoside-, and peptide-based bioconjugates are easily labeled with CO by a last-step palladium-catalyzed carbonylation. The choice of the [(12)C], [(13)C], or [(11)C] isotope opens the way to a new class of potential tracers or ligands easily available for various applications.
authors.affiliation: Université de Bordeaux , Institut des Sciences Moléculaires, UMR-CNRS 5255, 351, Cours de la Libération, 33405 Talence Cedex, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Cornilleau
authors.forename: Hélène
authors.initials: H
authors.lastname: Audrain
authors.forename: Aude
authors.initials: A
authors.lastname: Guillemet
authors.forename: Philippe
authors.initials: P
authors.lastname: Hermange
authors.forename: Eric
authors.initials: E
authors.lastname: Fouquet
mesh_terms: D002247:Carbon Isotopes / Q000737:chemistry; D002248:Carbon Monoxide / Q000737:chemistry*; D002250:Carbon Radioisotopes / Q000737:chemistry*; D002384:Catalysis; D007155:Immunologic Factors / Q000737:chemistry*; D007553:Isotope Labeling / Q000379:methods*; D015394:Molecular Structure
chemical_list: D002247:Carbon Isotopes; D002250:Carbon Radioisotopes; D007155:Immunologic Factors; D002248:Carbon Monoxide