title: Correlation Between Abnormal Platelet Count and Respiratory Viral Infection in Patients From Cheonan, Korea.
abstract: BACKGROUND
  In this study, the effects of viral infections on platelet (PLT) count have been reported. This study examined the correlation between PLT count and respiratory virus (RV) infections.
  
  
  METHODS
  Patients who visited Dankook University Hospital between December 2006 and February 2014 with symptoms of suspected RV infection were recruited. Multiplex reverse transcriptase polymerase chain reactions identified the causative virus(es). PLT counts were analyzed with respect to virus, age and sex of the patient, and length of hospital stay.
  
  
  RESULTS
  Of the 8,147 patients, 62.8% were RV-positive, and 18.6% of RV-positive patients had abnormal PLT counts. There were no differences in the rates of abnormal PLT counts between single-infection and virus co-infection cases. In RV infection patients, the incidence of abnormal PLT count increased with age and varied depending on the RV infection type. Patients with abnormal PLT count stayed in hospital longer than those with normal PLT count.
  
  
  CONCLUSIONS
  The incidence of thrombocytopenia was higher among the elderly; in younger patients, thrombocytosis was more prevalent than thrombocytopenia. Respiratory tract infections caused by different viruses resulted in varied PLT count changes. Further systematic research of PLT count changes related to viral infections is required.
authors.affiliation: Department of Laboratory Medicine, Dankook University Hospital, Cheonan, Korea.
authors.forename: Jae Kyung
authors.initials: JK
authors.lastname: Kim
authors.affiliation: Department of Laboratory Medicine, College of Medicine, Dankook University, Cheonan, Korea.
authors.forename: Jae-Sik
authors.initials: JS
authors.lastname: Jeon
authors.affiliation: Department of Laboratory Medicine, College of Medicine, Dankook University, Cheonan, Korea.
authors.forename: Jong Wan
authors.initials: JW
authors.lastname: Kim
authors.affiliation: Department of Dental Hygiene, College of Health Sciences, Dankook University, Cheonan, Chungnam, 330-714, Korea.
authors.forename: Ga-Yeon
authors.initials: GY
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D056910:Republic of Korea; D012141:Respiratory Tract Infections / Q000097:blood* / Q000821:virology*; D014777:Virus Diseases / Q000097:blood*; D055815:Young Adult
keywords: age group; influenza virus; length of hospital stay; multiplex PCR; respiratory sincytial virus; thrombocytopenia; thrombocytosis