title: [Antiphosphatidylethanolamine antibody as a marker of antiphospholipid syndrome?].
abstract: Antibody to phosphatidylethanolamine (aPE) are observed in thrombotic or obstetric manifestations suggestive of antiphospholipid syndrome (APS). aPE seem to be markers of thrombotic risk independent of conventional antiphospholipid antibodies (aPL). aPE assays are not standardized. There is no therapeutic recommendation for isolated aPE patients with thrombotic or obstetric events. Prospective studies have to be carried to better define the therapeutic management of these patients. Value of aPE in APS criteria is still not established.
authors.affiliation: CHRU de Lille, hôpital Huriez, service de médecine interne et d'explorations vasculaires, 59037 Lille cedex, France.
authors.forename: Cécile Marie
authors.initials: CM
authors.lastname: Yelnik
authors.affiliation: CHRU de Lille, centre de biologie pathologie génétique médicale, institut d'immunologie, 59037 Lille cedex, France.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Dubucquoi
authors.affiliation: CHRU de Lille, maternité Jeanne-de-Flandres, service de pathologie obstétricale, 59037 Lille cedex, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Houfflin-Debarge
authors.affiliation: CHRU de Lille, hôpital Huriez, service de médecine interne et d'explorations vasculaires, 59037 Lille cedex, France. Electronic address: lambertmd@gmail.com.
authors.forename: Marc
authors.initials: M
authors.lastname: Lambert
mesh_terms: D017152:Antibodies, Antiphospholipid / Q000032:analysis / Q000097:blood*; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology; D015415:Biomarkers / Q000032:analysis / Q000097:blood*; D005260:Female; D006801:Humans; D010714:Phosphatidylethanolamines / Q000276:immunology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology; D013927:Thrombosis / Q000097:blood / Q000175:diagnosis / Q000276:immunology
chemical_list: D017152:Antibodies, Antiphospholipid; D015415:Biomarkers; D010714:Phosphatidylethanolamines; C483858:phosphatidylethanolamine