title: Zosteriform configuration of multiple eccrine spiradenomas of the scalp.
abstract: BACKGROUND
  Eccrine spiradenoma (ES) is a benign adnexal tumor predominantly located in the head and neck regions. Multiple neoplasms located on the scalp have been reported but never with a zosteriform configuration on the first trigeminal area.
  
  
  METHODS
  We describe an original case report of a 75-year-old Caucasian man presenting multiple subcutaneous blue and purple nodules disseminated on the first left trigeminal dermatome. All the nodules appeared gradually on a one-year period. Biopsy revealed a nodular adnexal tumor in the dermis without malignant eccrine spiradenoma (MES) transformation. The surgical procedure was performed in a manner to protect the galea aponeurotica in the upper half on the first left trigeminal area. The frontalis muscle was raised with the surgical specimen in the lower half of the first trigeminal area. A split-thickness skin graft was applied on the surgical defect. Histological examination revealed multilobular well-defined tumors located in the dermis.
  
  
  CONCLUSIONS
  The presence of multiple subcutaneous nodules in a trigeminal pattern should suggest a multiple localized zosteriform ES. The diagnosis is focused on clinical findings and the treatment is based on a large surgical excision. The histological examination is essential for not to fail a MES transformation.
authors.affiliation: Department of Maxillofacial, Plastic Reconstructive and Aesthetic Surgery, Nancy University Hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54000 Nancy, France. Electronic address: t.sorin@chu-nancy.fr.
authors.forename: T
authors.initials: T
authors.lastname: Sorin
authors.affiliation: Department of Anatomical Pathology, Nancy University Hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54000 Nancy, France.
authors.forename: J-M
authors.initials: JM
authors.lastname: Vignaud
authors.affiliation: Department of Maxillofacial, Plastic Reconstructive and Aesthetic Surgery, Nancy University Hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54000 Nancy, France.
authors.forename: T
authors.initials: T
authors.lastname: Colson
authors.affiliation: Department of Anatomical Pathology, Nancy University Hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54000 Nancy, France.
authors.forename: G
authors.initials: G
authors.lastname: Gauchotte
authors.affiliation: Department of Maxillofacial, Plastic Reconstructive and Aesthetic Surgery, Nancy University Hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54000 Nancy, France.
authors.forename: A
authors.initials: A
authors.lastname: De Runz
authors.affiliation: Department of Maxillofacial, Plastic Reconstructive and Aesthetic Surgery, Nancy University Hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54000 Nancy, France.
authors.forename: M
authors.initials: M
authors.lastname: Brix
authors.affiliation: Department of Dermatology, Nancy university Hospital, rue du Morvan, 54511 Vandoeuvre-lès-Nancy, France.
authors.forename: J-F
authors.initials: JF
authors.lastname: Cuny
authors.affiliation: Department of Maxillofacial, Plastic Reconstructive and Aesthetic Surgery, Nancy University Hospital, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54000 Nancy, France.
authors.forename: E
authors.initials: E
authors.lastname: Simon
mesh_terms: D018250:Acrospiroma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D000368:Aged; D001706:Biopsy; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D012535:Scalp / Q000473:pathology / Q000601:surgery*; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D016038:Skin Transplantation; D014057:Tomography, X-Ray Computed
keywords: Cell transformation; Eccrine glands; Forehead; Front; Glande eccrine; Nerf trigéminal; Sweat gland neoplasms; Transformation cellulaire; Trigeminal nerve; Tumeur des glandes sudoripares