title: Prognostic markers of acute decompensated heart failure: the emerging roles of cardiac biomarkers and prognostic scores.
abstract: Rapidly assessing outcome in patients with acute decompensated heart failure is important but prognostic factors may differ from those used routinely for stable chronic heart failure. Multiple plasma biomarkers, besides the classic natriuretic peptides, have recently emerged as potential prognosticators. Furthermore, prognostic scores that combine clinical and biochemical data may also be useful. However, compared with the scores used in chronic heart failure, scores for acute decompensated heart failure have not been validated. This article reviews potential biomarkers, with a special focus on biochemical biomarkers, and possible prognostic scores that could be used by the clinician when assessing outcome in patients with acute heart failure.
authors.affiliation: UMR-S 942 "Biomarqueurs et Insuffisances Cardiaques", Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Paris, France; Cardiology department, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France; DHU FIRE, Sorbonne Paris Cité, Paris, France. Electronic address: alain.cohen-solal@inserm.fr.
authors.forename: Alain
authors.initials: A
authors.lastname: Cohen-Solal
authors.affiliation: UMR-S 942 "Biomarqueurs et Insuffisances Cardiaques", Paris, France; Emergency department, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, Paris, France.
authors.forename: Said
authors.initials: S
authors.lastname: Laribi
authors.affiliation: UMR-S 942 "Biomarqueurs et Insuffisances Cardiaques", Paris, France; Cardiology department, Steel Memorial Yawata Hospital, Kitakyushu, Japan.
authors.forename: Shiro
authors.initials: S
authors.lastname: Ishihara
authors.affiliation: UMR-S 942 "Biomarqueurs et Insuffisances Cardiaques", Paris, France; Cardiology and cardiovascular medicine division, Fondazione Toscana Gabriele Monasterio per la Ricerca Medica e di Sanità Pubblica, CNR-Regione Toscana, Pisa, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Vergaro
authors.affiliation: Cardiology department, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France.
authors.forename: Mathilde
authors.initials: M
authors.lastname: Baudet
authors.affiliation: UMR-S 942 "Biomarqueurs et Insuffisances Cardiaques", Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Paris, France; Cardiology department, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France; DHU FIRE, Sorbonne Paris Cité, Paris, France.
authors.forename: Damien
authors.initials: D
authors.lastname: Logeart
authors.affiliation: UMR-S 942 "Biomarqueurs et Insuffisances Cardiaques", Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Paris, France; DHU FIRE, Sorbonne Paris Cité, Paris, France; Anaesthesia-ICU department, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, Paris, France.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Mebazaa
authors.affiliation: UMR-S 942 "Biomarqueurs et Insuffisances Cardiaques", Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Paris, France; DHU FIRE, Sorbonne Paris Cité, Paris, France; Anaesthesia-ICU department, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, Paris, France.
authors.forename: Etienne
authors.initials: E
authors.lastname: Gayat
authors.affiliation: UMR-S 942 "Biomarqueurs et Insuffisances Cardiaques", Paris, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Vodovar
authors.affiliation: Cardiology department, hospital Virgen de la Arrixaca, school of medicine, university of Murcia, Murcia, Spain.
authors.forename: Domingo A
authors.initials: DA
authors.lastname: Pascual-Figal
authors.affiliation: UMR-S 942 "Biomarqueurs et Insuffisances Cardiaques", Paris, France; Cardiology department, CHU de Besançon, Besançon, France.
authors.forename: Marie-France
authors.initials: MF
authors.lastname: Seronde
mesh_terms: D000208:Acute Disease; D015415:Biomarkers / Q000097:blood*; D003661:Decision Support Techniques; D006333:Heart Failure / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D011237:Predictive Value of Tests; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors
chemical_list: D015415:Biomarkers
keywords: Acute decompensated heart failure; Biomarkers; Biomarqueurs; Insuffisance cardiaque aiguë; Natriuretic peptides; Peptides natriurétiques; Prognosis; Pronostic; Scores; Scores de risque