title: Clinical management of organophosphate poisoning in pregnancy.
abstract: BACKGROUND
  Acute organophosphorus pesticide poisoning during pregnancy may lead to spontaneous abortion. Now, there is no definite strategy focused on maintaining pregnancy.
  
  
  METHODS
  This is a retrospective analysis of 2 cases of organophosphorus poisoning during pregnancy. All patients received penehyclidine hydrochloride injection,until the tracheobronchial tree is cleared of the secretions, and most secretions were dried. In addition, magnesium sulfate was used in one woman for the correction of hyperdynamic uterine activity.
  
  
  RESULTS
  Two women all survived, one fetus died of spontaneous abortion, and one fetus died of incoordinate uterine action. The 2 women had no significant complications during postpartum period.
  
  
  CONCLUSIONS
  Penehyclidine hydrochloride and magnesium sulfate may be used to treat organophosphorus during pregnancy. However, futher study and new experimental need to be designed.
authors.affiliation: Department of Respiratory and Critical Care Medicine Pingjin Hospital, Affiliated Hospital of Armed Police Logistics College 220, Cheng-Lin Road, Tianjin, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Sun
authors.affiliation: Department of Respiratory and Critical Care Medicine Pingjin Hospital, Affiliated Hospital of Armed Police Logistics College 220, Cheng-Lin Road, Tianjin, China.
authors.forename: Guo-qiang
authors.initials: GQ
authors.lastname: Li
authors.affiliation: Department of Respiratory and Critical Care Medicine Pingjin Hospital, Affiliated Hospital of Armed Police Logistics College 220, Cheng-Lin Road, Tianjin, China.
authors.forename: Peng-bo
authors.initials: PB
authors.lastname: Yan
authors.affiliation: Department of Respiratory and Critical Care Medicine Pingjin Hospital, Affiliated Hospital of Armed Police Logistics College 220, Cheng-Lin Road, Tianjin, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Respiratory and Critical Care Medicine Pingjin Hospital, Affiliated Hospital of Armed Police Logistics College 220, Cheng-Lin Road, Tianjin, China.
authors.forename: Guo-feng
authors.initials: GF
authors.lastname: Li
authors.affiliation: Department of Respiratory and Critical Care Medicine Pingjin Hospital, Affiliated Hospital of Armed Police Logistics College 220, Cheng-Lin Road, Tianjin, China. Electronic address: sunliangys@sina.com.
authors.forename: Lu-Qing
authors.initials: LQ
authors.lastname: Wei
mesh_terms: D000328:Adult; D004006:Dichlorvos / Q000633:toxicity; D005260:Female; D006801:Humans; D062025:Organophosphate Poisoning / Q000150:complications* / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced* / Q000628:therapy; D013406:Suicide, Attempted
chemical_list: D004006:Dichlorvos