title: BODIPY-based fluorescent thermometer as a lysosome-targetable probe: how the oligo(ethylene glycols) compete photoinduced electron transfer.
abstract: A novel BODIPY-based fluorescent thermometer, which shows a lysosome-targeting property, was successfully prepared. Due to the electron-donating ability of the oligo(ethylene glycols), the photoinduced electron-transfer pathway from morpholine to BODIPY dye is blocked. The fluorescence of the thermometer quenched by intramolecular rotation at room temperature was progressively enhanced during heating due to the increased microviscosity around the fluorophore.
authors.affiliation: Department of Polymer Materials, Shanghai University, Nanchen Road 333, 200444, Shanghai (P.R. China).
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.forename: Yongquan
authors.initials: Y
authors.lastname: Wu
authors.forename: Yanlin
authors.initials: Y
authors.lastname: Shi
authors.forename: Pan
authors.initials: P
authors.lastname: Tao
authors.forename: Xing
authors.initials: X
authors.lastname: Fan
authors.forename: Xinyan
authors.initials: X
authors.lastname: Su
authors.forename: Gui-Chao
authors.initials: GC
authors.lastname: Kuang
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D004579:Electron Transport; D005026:Ethylene Glycols / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008247:Lysosomes / Q000737:chemistry* / Q000378:metabolism; D009025:Morpholines / Q000737:chemistry*; D013821:Thermometers
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D005026:Ethylene Glycols; D005456:Fluorescent Dyes; D009025:Morpholines
keywords: BODIPY; analytical methods; electron transfer; fluorescent probes; lysosome