title: Immunohistochemistry in dermatopathology.
abstract: BACKGROUND
  Immunohistochemistry is not a diagnostic test but a highly valuable tool that requires interpretation within a context.
  
  
  OBJECTIVE
  To review the current status and limitations of immunohistochemistry in dermatopathology.
  
  
  METHODS
  English-language literature published between 1980 and 2014.
  
  
  CONCLUSIONS
  Although immunohistochemistry is rarely completely specific or sensitive, it is an important adjunctive technique in dermatopathology and can be helpful in a series of diagnostic dilemmas.
authors.affiliation: From the Departments of Dermatology and Laboratory Medicine, Geisinger Medical Center, Danville, Pennsylvania.
authors.forename: Tammie
authors.initials: T
authors.lastname: Ferringer
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012867:Skin / Q000378:metabolism / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor