title: Impaired executive functioning after left anterior insular stroke: a case report.
abstract: Given the insular's anatomic complexity and functional interconnectivity, acute lesions may result in varied clinical presentations, including autonomic, somatosensory, perceptual, motor, affective, and cognitive deficits. Although functional neuroimaging studies have demonstrated its role in executive functions, no clinical manifestations have been reported to date. We present the case of a woman with an acute left anterior insular infarction leading to executive (i.e., word and design fluency, mental flexibility, sustained attention, inhibitory control), but not language, visuoperceptual, or memory impairment. This case confirms the left anterior insula's involvement in executive functioning and suggests that an infarction may result in executive impairment.
authors.affiliation: a Laboratory of Cognitive Neuroscience, School of Psychology , Aristotle University of Thessaloniki , Thessaloniki , Greece.
authors.forename: Ioanna
authors.initials: I
authors.lastname: Markostamou
authors.forename: Jobst
authors.initials: J
authors.lastname: Rudolf
authors.forename: Iakovos
authors.initials: I
authors.lastname: Tsiptsios
authors.forename: Mary H
authors.initials: MH
authors.lastname: Kosmidis
mesh_terms: D002540:Cerebral Cortex / Q000473:pathology*; D056344:Executive Function; D005260:Female; D007839:Functional Laterality; D006801:Humans; D001523:Mental Disorders / Q000209:etiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D020521:Stroke / Q000150:complications* / Q000473:pathology
keywords: executive functioning; insula; lesion; stroke