title: [Elastography shows promise in testicular cancer detection].
abstract: OBJECTIVE
  Elastography is a novel imaging technology that shows promise in the identification of anatomic structures. The widespread use of ultrasound for screening testicular tumors in patients with cancer risk factors highlights unclassified testicular micronodules. We investigated the ability of elastography to accurately diagnose testicular nodules.
  
  
  METHODS
  Patients with clinical testicular nodules were assigned to undergo elastography in a prospective study. The imaging was carried out by a single radiologist using a static elastography unit with a 9-14MHz frequency linear transducer, to identify hardness score, loss of architecture of testicular parenchyma, and surrounding effect. When orchidectomy was required, the corresponding specimens were subjected to hematoxylin and eosin staining for histologic correlation.
  
  
  RESULTS
  We imaged 34 testicular lesions: 26/34 (76%) malignant tumors and 8/34 (24%) non-tumor lesion including 4 hematomas, 3 orchitis and 1 ischemia. Se, Sp, PPV and NPV of hardness in elastography in differentiating between malignant and benign tissue was found to be 96.2%, 37.5%, 83%, and 75%, respectively. Further, for recognizing cancer, the loss of architecture of the testicular parenchyma detecting in elastography was 92.3%, 75%, 92.3%, and 75%, respectively, and the surrounding effect was 84.6%, 87.5%, 95.6% and 63.6%, respectively.
  
  
  CONCLUSIONS
  Elastography may be a promising tool at diagnosing testicular tumor when the loss of architecture and the surrounding effect were present. Further studies are needed to evaluate whether the utility of elastography is worth pursuing to identify of unclassified testicular micronodules.
  
  
  METHODS
  3.
authors.affiliation: Service d'urologie, hôpital Archet 2, 151, route Saint-Antoine-de-Ginestière, 06200 Nice, France. Electronic address: marsaud.a@chu-nice.fr.
authors.forename: A
authors.initials: A
authors.lastname: Marsaud
authors.affiliation: Service d'urologie, hôpital Archet 2, 151, route Saint-Antoine-de-Ginestière, 06200 Nice, France. Electronic address: durand.m@chu-nice.fr.
authors.forename: M
authors.initials: M
authors.lastname: Durand
authors.affiliation: Service de radiologie, hôpital Pasteur, 30, avenue de la Voie-Romaine, 06000 Nice, France. Electronic address: raffaelli.cp@chu-nice.fr.
authors.forename: C
authors.initials: C
authors.lastname: Raffaelli
authors.affiliation: Service d'urologie, hôpital Archet 2, 151, route Saint-Antoine-de-Ginestière, 06200 Nice, France. Electronic address: carpentier.x@chu-nice.fr.
authors.forename: X
authors.initials: X
authors.lastname: Carpentier
authors.affiliation: Service d'urologie, hôpital Archet 2, 151, route Saint-Antoine-de-Ginestière, 06200 Nice, France. Electronic address: rouscoff.y@chu-nice.fr.
authors.forename: Y
authors.initials: Y
authors.lastname: Rouscoff
authors.affiliation: Service d'urologie, hôpital Archet 2, 151, route Saint-Antoine-de-Ginestière, 06200 Nice, France. Electronic address: tibi.b@chu-nice.fr.
authors.forename: B
authors.initials: B
authors.lastname: Tibi
authors.affiliation: Service d'urologie, hôpital Archet 2, 151, route Saint-Antoine-de-Ginestière, 06200 Nice, France.
authors.forename: A
authors.initials: A
authors.lastname: Floc'h
authors.affiliation: Service d'urologie, hôpital Archet 2, 151, route Saint-Antoine-de-Ginestière, 06200 Nice, France.
authors.forename: M H
authors.initials: MH
authors.lastname: De Villeneuve
authors.affiliation: Service d'urologie, hôpital Archet 2, 151, route Saint-Antoine-de-Ginestière, 06200 Nice, France.
authors.forename: R
authors.initials: R
authors.lastname: Haider
authors.affiliation: Service d'anatomopathologie, hôpital Pasteur, 30, avenue de la Voie-Romaine, 06000 Nice, France. Electronic address: ambrosetti.d@chu-nice.fr.
authors.forename: D
authors.initials: D
authors.lastname: Ambrosetti
authors.affiliation: Hopital CIMIEZ, 4, avenue Victoria, 06003 Nice cedex 1, France. Electronic address: fontas.e@chu-nice.fr.
authors.forename: E
authors.initials: E
authors.lastname: Fontas
authors.affiliation: Service de radiologie, hôpital Pasteur, 30, avenue de la Voie-Romaine, 06000 Nice, France. Electronic address: padovani.b@chu-nice.fr.
authors.forename: B
authors.initials: B
authors.lastname: Padovani
authors.affiliation: Service d'urologie, hôpital Archet 2, 151, route Saint-Antoine-de-Ginestière, 06200 Nice, France. Electronic address: amiel.j@chu-nice.fr.
authors.forename: J
authors.initials: J
authors.lastname: Amiel
authors.affiliation: Service d'urologie, hôpital Archet 2, 151, route Saint-Antoine-de-Ginestière, 06200 Nice, France. Electronic address: chevallier.d@chu-nice.fr.
authors.forename: D
authors.initials: D
authors.lastname: Chevallier
mesh_terms: D000293:Adolescent; D000328:Adult; D054459:Elasticity Imaging Techniques; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging*; D055815:Young Adult
keywords: Cancer; Elastography; Scrotum; Testicule; Testis; Ultrasound; Échographie; Élastographie