title: Perceived 10-year change in respiratory health: reliability and predictive ability.
abstract: OBJECTIVE
  To investigate the usefulness of a self-reported respiratory health transition question over 10 years through reliability, ability to capture long-term asthma trajectory and predictive ability.
  
  
  METHODS
  In two 20-year cohorts (Asthma-E3N, n = 16,371, 61-88 years; EGEA, n = 1254, 27-82 years), perceived 10-year change in respiratory health ("Overall, in the last 10 years, do you think that your bronchial or respiratory health has changed?" if yes: "Has it improved/deteriorated?") was studied in relation with change in respiratory medication dispensation and lung function, with change in asthma status measured over the same period of time, and with subsequent asthma-related outcomes.
  
  
  RESULTS
  Perceived deterioration (14% in Asthma-E3N) was associated with increased dispensations of respiratory medications over time (from 17% with >2 dispensations in 2004 to 26% in 2010). Report of perceived deterioration (13% in EGEA) was related to a lung function decline steeper by 9.3 mL/year as compared to perceived improvement. In both cohorts, change (improvement or deterioration) was more often perceived by participants with than without asthma (>45% vs <20%) and was dominant among participants with persistent current asthma (77%). Perceived deterioration was related to poorer asthma control 7 years later and to higher use of oral corticosteroids in the following 18 months.
  
  
  CONCLUSIONS
  The proposed simple self-reported respiratory health transition question over 10 years allows predicting part of the long-term trajectory of asthma.
authors.affiliation: Institut National de la Santé et de la Recherche Médicale (INSERM), CESP Centre for Research in Epidemiology and Population Health, U1018, Respiratory and Environmental Epidemiology Team, F-94807 Villejuif, France; Univ Paris-Sud, UMRS1018, F-94807 Villejuif, France. Electronic address: margaux.sanchez@inserm.fr.
authors.forename: Margaux
authors.initials: M
authors.lastname: Sanchez
authors.affiliation: Institut National de la Santé et de la Recherche Médicale (INSERM), CESP Centre for Research in Epidemiology and Population Health, U1018, Respiratory and Environmental Epidemiology Team, F-94807 Villejuif, France; Univ Paris-Sud, UMRS1018, F-94807 Villejuif, France.
authors.forename: Raphaëlle
authors.initials: R
authors.lastname: Varraso
authors.affiliation: Institut National de la Santé et de la Recherche Médicale (INSERM), CESP Centre for Research in Epidemiology and Population Health, U1018, Respiratory and Environmental Epidemiology Team, F-94807 Villejuif, France; Univ Paris-Sud, UMRS1018, F-94807 Villejuif, France.
authors.forename: Jean
authors.initials: J
authors.lastname: Bousquet
authors.affiliation: Univ Paris-Sud, UMRS1018, F-94807 Villejuif, France; Institut National de la Santé et de la Recherche Médicale (INSERM), CESP Centre for Research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health Team, F-94807 Villejuif, France.
authors.forename: Françoise
authors.initials: F
authors.lastname: Clavel-Chapelon
authors.affiliation: Univ Grenoble Alpes, Institut Albert Bonniot, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, F-38000 Grenoble, France; Clinique Universitaire de Pneumologie, Centre Hospitalier Universitaire de Grenoble, F-38000 Grenoble, France; Institut National de la Santé et de la Recherche Médicale (INSERM), U1055, Laboratoire de Bioénergétique fondamentale et Appliquée, F-38000 Grenoble, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Pison
authors.affiliation: Institut National de la Santé et de la Recherche Médicale (INSERM), CESP Centre for Research in Epidemiology and Population Health, U1018, Respiratory and Environmental Epidemiology Team, F-94807 Villejuif, France; Univ Paris-Sud, UMRS1018, F-94807 Villejuif, France.
authors.forename: Francine
authors.initials: F
authors.lastname: Kauffmann
authors.affiliation: Assistance Publique Hôpitaux de Paris, Service de Pneumologie, DHU Thorax Innovation, Hôpital Bicêtre, F-94270 Le Kremlin-Bicêtre, France; INSERM U999, LabEx LERMIT, Centre Chirurgical Marie Lannelongue, F-92350 Le Plessis-Robinson, France; Univ Paris-Sud, Faculté de Médecine, F-94270 Le Kremlin-Bicêtre, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Humbert
authors.affiliation: Univ Grenoble Alpes, Institut Albert Bonniot, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, F-38000 Grenoble, France; Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Albert Bonniot, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, F-38000 Grenoble, France; Centre Hospitalier Universitaire de Grenoble, Institut Albert Bonniot, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, F-38000 Grenoble, France.
authors.forename: Valérie
authors.initials: V
authors.lastname: Siroux
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000188:drug therapy / Q000523:psychology*; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D015203:Reproducibility of Results; D057566:Self Report; D016896:Treatment Outcome
keywords: Asthma; Longitudinal; Perceived health; Respiratory health; Variability