title: On the feasibility of utilizing allogeneic bone blocks for atrophic maxillary augmentation.
abstract: OBJECTIVE
  This systematic review was aimed at assessing the feasibility by means of survival rate, histologic analysis, and causes of failure of allogeneic block grafts for augmenting the atrophic maxilla.
  
  
  METHODS
  A literature search was conducted by one reviewer in several databases. Articles were included in this systematic review if they were human clinical trials in which outcomes of allogeneic bone block grafts were studied by means of survival rate. In addition other factors were extracted in order to assess their influence upon graft failure.
  
  
  RESULTS
  Fifteen articles fulfilled the inclusion criteria and subsequently were analyzed in this systematic review. A total of 361 block grafts could be followed 4 to 9 months after the surgery, of which 9 (2.4%) failed within 1 month to 2 months after the surgery. Additionally, a weighed mean 4.79 mm (95% CI: 4.51-5.08) horizontal bone gain was computed from 119 grafted sites in 5 studies. Regarding implant cumulative survival rate, the weighed mean was 96.9% (95% CI: 92.8-98.7%), computed from 228 implants over a mean follow-up period of 23.9 months. Histologic analysis showed that allogeneic block grafts behave differently in the early stages of healing when compared to autogenous block grafts.
  
  
  CONCLUSIONS
  Atrophied maxillary reconstruction with allogeneic bone block grafts represents a reliable option as shown by low block graft failure rate, minimal resorption, and high implant survival rate.
authors.affiliation: Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
authors.forename: Alberto
authors.identifier: 0000-0001-8292-1927
authors.initials: A
authors.lastname: Monje
authors.affiliation: Private practice, Palm Beach, FL, USA.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Pikos
authors.affiliation: Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
authors.forename: Hsun-Liang
authors.initials: HL
authors.lastname: Chan
authors.affiliation: Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
authors.forename: Fernando
authors.initials: F
authors.lastname: Suarez
authors.affiliation: Department of Oral Surgery and Implant Dentistry, International University of Catalonia, Barcelona, Spain.
authors.forename: Jordi
authors.initials: J
authors.lastname: Gargallo-Albiol
authors.affiliation: Department of Oral Surgery and Implant Dentistry, International University of Catalonia, Barcelona, Spain.
authors.forename: Federico
authors.initials: F
authors.lastname: Hernández-Alfaro
authors.affiliation: Department of Oral Surgery and Implant Dentistry, University of Granada, Granada, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Galindo-Moreno
authors.affiliation: Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
authors.forename: Hom-Lay
authors.initials: HL
authors.lastname: Wang
mesh_terms: D001284:Atrophy / Q000473:pathology / Q000601:surgery*; D001862:Bone Resorption / Q000473:pathology / Q000601:surgery*; D016025:Bone Transplantation; D015921:Dental Implants; D006801:Humans; D008437:Maxilla / Q000473:pathology / Q000601:surgery; D010012:Osteogenesis; D015996:Survival Rate
chemical_list: D015921:Dental Implants