title: Macular findings obtained by spectral domain optical coherence tomography in retinopathy of prematurity.
abstract: Purpose. To examine the macular findings obtained with spectral domain optical coherence tomography (SD OCT) in infants with retinopathy of prematurity (ROP). Materials and Methods. The macular SD OCT images of 190 premature infants were analyzed. Data regarding central foveal thickness (CFT), cystoid macular edema (CME), and cyst grading were compared. The relationships of CFT with gestational age and birth weight were investigated. Results. The results were obtained from 358 eyes of 179 infants (81 females and 98 males) of a mean gestational age of 30.9 ± 2.7 weeks and a mean birth weight of 1609 ± 477 g. ROP was diagnosed in 126 eyes and CME in 139 eyes. A significantly greater percentage of eyes with ROP were found to have CME (54%) compared to eyes without ROP (31%; P = 0.001). The incidence of CME was 46.3% for stage 1 ROP, 57.1% for stage 2, and 87.5% for stage 3. There was a weakly inverse correlation between CFT, gestational age, and birth weight (P = 0.025, r = -0.227; P = 0.002, r = -0.182, resp., Spearman correlation test). Conclusions. High-quality SD OCT images can be obtained from premature infants using the iVue system. Severity and frequency of CME in premature infants increase as stage of ROP increases.
authors.affiliation: Department of Ophthalmology, Antalya Training and Research Hospital, 07030 Antalya, Turkey.
authors.forename: Muhammet Kazim
authors.initials: MK
authors.lastname: Erol
authors.affiliation: Department of Ophthalmology, Zekai Tahir Burak Women's Health Training and Research Hospital, 06110 Ankara, Turkey.
authors.forename: Ozdemir
authors.initials: O
authors.lastname: Ozdemir
authors.affiliation: Department of Ophthalmology, Antalya Training and Research Hospital, 07030 Antalya, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Turgut Coban
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Akdeniz University, 07070 Antalya, Turkey.
authors.forename: Ahmet Burak
authors.initials: AB
authors.lastname: Bilgin
authors.affiliation: Department of Ophthalmology, Antalya Training and Research Hospital, 07030 Antalya, Turkey.
authors.forename: Berna
authors.initials: B
authors.lastname: Dogan
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Balıkesir University, 10145 Balıkesir, Turkey.
authors.forename: Esin
authors.initials: E
authors.lastname: Sogutlu Sari
authors.affiliation: Department of Ophthalmology, Antalya Training and Research Hospital, 07030 Antalya, Turkey.
authors.forename: Devrim
authors.initials: D
authors.lastname: Toslak