title: Progressive adaptation of a CpGV isolate to codling moth populations resistant to CpGV-M.
abstract: The NPP-R1 isolate of CpGV is able to replicate on CpGV-M-resistant codling moths. However, its efficacy is not sufficient to provide acceptable levels of control in natural (orchard) conditions. A laboratory colony derived from resistant codling moths was established, which exhibited a homogeneous genetic background and a resistance level more than 7000 fold. By successive cycles of replication of NPP-R1 in this colony, we observed a progressive increase in efficacy. After 16 cycles (isolate 2016-r16), the efficacy of the virus isolate was equivalent to that of CpGV-M on susceptible insects. This isolate was able to control both CpGV-M-susceptible and CpGV-M-resistant insects with similar efficacy. No reduction in the levels of occlusion body production in susceptible larvae was observed for 2016-r16 compared to CpGV-M.
authors.affiliation: LGEI, Ecole des Mines d'Alès, Institut Mines-Telecom et Université de Montpellier Sud de France, 6, Avenue de Clavières, 30319 Alès, France. samantha.besse@arysta.com.
authors.forename: Benoît
authors.initials: B
authors.lastname: Graillot
authors.affiliation: LGEI, Ecole des Mines d'Alès, Institut Mines-Telecom et Université de Montpellier Sud de France, 6, Avenue de Clavières, 30319 Alès, France. mberling@crea.fr.
authors.forename: Marie
authors.initials: M
authors.lastname: Berling
authors.affiliation: INRA, 6, Avenue de Clavières, 30319 Alès, France. christine.blachere-lopez@mines-ales.fr.
authors.forename: Christine
authors.initials: C
authors.lastname: Blachere-López
authors.affiliation: INRA, Unité PSH, Agroparc, 84914 Avignon Cedex 9, France. myriam.siegwart@avignon.inra.fr.
authors.forename: Myriam
authors.initials: M
authors.lastname: Siegwart
authors.affiliation: Natural Plant Protection, Arysta LifeScience group, Avenue Léon Blum, 64000 Pau, France. samantha.besse@arysta.com.
authors.forename: Samantha
authors.initials: S
authors.lastname: Besse
authors.affiliation: LGEI, Ecole des Mines d'Alès, Institut Mines-Telecom et Université de Montpellier Sud de France, 6, Avenue de Clavières, 30319 Alès, France. miguel.lopez-ferber@mines-ales.fr.
authors.forename: Miguel
authors.initials: M
authors.lastname: López-Ferber
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D025722:Granulovirus / Q000145:classification / Q000235:genetics / Q000502:physiology*; D009036:Moths / Q000235:genetics / Q000276:immunology* / Q000502:physiology / Q000821:virology*; D010572:Pest Control, Biological