title: Resveratrol trimers from seed cake of Paeonia rockii.
abstract: In the course of screening natural products for antibacterial activities, a total acetone extract of the seed cake of Paeonia rockii showed significant effects against bacterial strains. Bioactivity-guided fractionation of the EtOAc-soluble fraction of the total acetone extract resulted in the isolation and identification of five resveratrol trimers, including rockiiol C (1), gnetin H (2), suffruticosol A (3), suffruticosol B (4) and suffruticosol C (5). The relative configuration of these compounds was elucidated mainly by comprehensive 1D and 2D-NMR experiments. Compound 1 was a new compound. All isolated compounds exhibited strong antibacterial activities against Gram-positive bacteria.
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China. liuputju@163.com.
authors.forename: Pu
authors.initials: P
authors.lastname: Liu
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China. gjiayu@126.com.
authors.forename: Yiran
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China. cruise1204@163.com.
authors.forename: Jiayu
authors.initials: J
authors.lastname: Gao
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China. zuyuang@126.com.
authors.forename: Zongyuan
authors.initials: Z
authors.lastname: Lu
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China. ywpq@163.com.
authors.forename: Weiping
authors.initials: W
authors.lastname: Yin
authors.affiliation: Chemical Engineering & Pharmaceutical College, Henan University of Science and Technology, Research Center on Wild Natural Resources of FUNIU Mountain, Luoyang 471023, China. dengliu20022002@aliyun.com.
authors.forename: Ruixue
authors.initials: R
authors.lastname: Deng
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D029596:Paeonia / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000077185:Resveratrol; D012639:Seeds / Q000737:chemistry*; D013267:Stilbenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D013267:Stilbenes; D000077185:Resveratrol