title: Seminal quality in the first fraction of ejaculate.
abstract: Semen samples from 40 patients were collected in consecutive fractions. The variability in semen quality of each fraction was then determined. The first ejaculated fraction (FEF) primarily contained prostatic secretions, while the second ejaculate fraction (SEF) held the majority of the spermatozoa suspended in the secretions from the seminal vesicle. Differences in sperm quality were observed when the FEF was compared to the SEF and the total ejaculate fraction (TEF). These included the seminal parameters (volume, sperm concentration, motility) and sperm DNA fragmentation (SDF). When compared to TEF and SEF, the FEF presented a lower volume, higher sperm concentration, higher motility rates, and lower SDF. The data suggest that the first fraction renders an improved subpopulation of spermatozoa, with lower SDF. Spermatozoa from this fraction and hence their use for ART may have a positive effect on fertilization and embryo development.
authors.affiliation: Clínica Ginemed and.
authors.forename: María
authors.initials: M
authors.lastname: Hebles
authors.forename: Monica
authors.initials: M
authors.lastname: Dorado
authors.forename: Miguel
authors.initials: M
authors.lastname: Gallardo
authors.forename: Mercedes
authors.initials: M
authors.lastname: González-Martínez
authors.forename: Pacual
authors.initials: P
authors.lastname: Sánchez-Martín
mesh_terms: D000328:Adult; D053938:DNA Fragmentation; D004542:Ejaculation; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000473:pathology; D011467:Prostate / Q000378:metabolism; D055101:Semen Analysis / Q000592:standards*; D012669:Seminal Vesicles / Q000502:physiology; D013076:Sperm Count; D013081:Sperm Motility; D013094:Spermatozoa / Q000502:physiology
keywords: Ejaculate; fraction; improvement; seminal parameters; sperm DNA fragmentation