title: A 3-year follow-up of ceria-stabilized zirconia/alumina nanocomposite (Ce-TZP/A) frameworks for fixed dental prostheses.
abstract: OBJECTIVE
  Zirconia/alumina nanocomposite stabilized with cerium oxide (Ce-TZP/A) shows significantly higher mechanical strength than yttrium-oxide-partially-stabilized zirconia (Y-TZP) and allows post-sintered machining that does not require any subsequent treatment. The aim of this prospective study was to assess the clinical performance of veneered Ce-TZP/A frameworks for fixed dental prostheses.
  
  
  METHODS
  Fifteen patients with 22 Ce-TZP/A fixed prostheses were included in this study. The fixed dental prostheses were cemented with resin cement (baseline) and were evaluated at baseline and at 1, 6, 12, 24 and 36 months after cementation. Clinical events, including fracture and loss of retention, secondary caries, and marginal integrity, were recorded. The biologic outcome was judged by comparing the pre-treatment and post-treatment bleeding on probing (BOP), and probing pocket depth (PPD) of the abutment teeth. Radiographic examination was also performed at 12, 24 and 36 months.
  
  
  RESULTS
  The mean observation period was 35.9±5.5 months. During this period, one abutment tooth was extracted due to root fracture and the survival rate was 95.2%. No significant change in BOP, PPD, and radiographic image was found during the 36-month follow-up period.
  
  
  CONCLUSIONS
  Within the limitations of this study, Ce-TZP/A was found to provide sufficient stability as a framework material in all regions. Special attention, however, must be paid to designing framework that provides sufficient support for the veneer. Furthermore, studies with longer observation periods and more patients are needed.
authors.affiliation: Department of Prosthodontics, Showa University School of Dentistry, Tokyo, Japan.
authors.forename: Shinpei
authors.initials: S
authors.lastname: Tanaka
authors.affiliation: Department of Prosthodontics, Showa University School of Dentistry, Tokyo, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Takaba
authors.affiliation: Department of Implant Dentistry, Showa University School of Dentistry, Tokyo, Japan.
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Ishiura
authors.affiliation: Department of Prosthodontics, Showa University School of Dentistry, Tokyo, Japan.
authors.forename: Emi
authors.initials: E
authors.lastname: Kamimura
authors.affiliation: Department of Prosthodontics, Showa University School of Dentistry, Tokyo, Japan. Electronic address: kazuyoshi@dent.showa-u.ac.jp.
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Baba
mesh_terms: D000537:Aluminum Oxide; D002484:Cementation; D002563:Cerium; D003738:Dental Cements; D003764:Dental Materials; D017267:Dental Prosthesis Design; D003801:Dental Veneers; D003781:Denture Retention / Q000379:methods*; D003830:Denture, Partial, Fixed; D005500:Follow-Up Studies; D006801:Humans; D011446:Prospective Studies; D019279:Resin Cements; D013997:Time Factors; D015040:Zirconium
chemical_list: C475766:Ce-TZP-Al2O3; D003738:Dental Cements; D003764:Dental Materials; D019279:Resin Cements; D002563:Cerium; D015040:Zirconium; D000537:Aluminum Oxide
keywords: Ceria-stabilized; Clinical evaluation; Fixed dental prostheses; Framework; Zirconia