title: Nocardia prosthetic knee infection successfully treated by one-stage exchange: case report and review.
abstract: A 64-year-old man with a history of sarcoidosis on corticosteroids and azathioprine was admitted to our hospital with complaints of worsening left knee pain and swelling for the past 3 weeks. His past medical history is also significant for severe osteoarthritis requiring a cemented total left knee arthroplasty 1 year ago. Diagnostic investigation during his hospital admission eventually led to the diagnosis of Nocardia nova knee prosthetic joint infection in the setting of a disseminated nocardiosis. He was successful treated by one-stage complete hardware exchange in conjunction with an adapted antibiotic therapy regimen (meropenem and doxycycline followed by ceftriaxone and doxycycline). Two years later, his recovery was deemed excellent.
authors.forename: F
authors.initials: F
authors.lastname: Laurent
authors.forename: H
authors.initials: H
authors.lastname: Rodriguez-Villalobos
authors.forename: O
authors.initials: O
authors.lastname: Cornu
authors.forename: B
authors.initials: B
authors.lastname: Vandercam
authors.forename: J C
authors.initials: JC
authors.lastname: Yombi
mesh_terms: D015897:Comorbidity; D020878:Device Removal; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007720:Knee Prosthesis / Q000009:adverse effects*; D008875:Middle Aged; D009617:Nocardia Infections / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery*; D020370:Osteoarthritis, Knee / Q000601:surgery; D016459:Prosthesis-Related Infections / Q000453:epidemiology / Q000601:surgery*; D012507:Sarcoidosis / Q000453:epidemiology
keywords: Immunodepression,; Knee,; Nocardia nova,; One-stage exchange; Prosthetic joint infection,; Sarcoidosis,