title: Chinese medicine treatment for menopausal symptoms in the UK health service: is a clinical trial warranted?
abstract: OBJECTIVE
  The aims of this pilot study were to evaluate treatment effects, ascertain safety and formulate best practice Chinese medicine protocols relevant for London women suffering from menopausal symptoms.
  
  
  METHODS
  This clinical pilot study employed a case series design within a wider action-based research project. 117 perimenopausal women between 45 and 55 years of age recruited from the general population were treated for menopausal symptoms by six experienced practitioners of Chinese medicine at the Polyclinic of the University of Westminster. Practitioners were instructed to treat as near to their usual practice style as possible. This involved using Chinese herbal medicine and/or acupuncture along with dietary and lifestyle advice. A maximum of 12 treatments over 6 months was allowed per patient.
  
  
  METHODS
  The menopause specific quality of life questionnaire (MenQoL), the Greene climacteric scale, and flushing diaries were used to evaluate treatment outcomes. Liver and kidney function tests were carried out at intake and after 1, 6 and 12 treatments to evaluate the safety particularly in relation to the use of herbal medicines.
  
  
  RESULTS
  Patients showed significant improvement across all domains measured by the MenQoL and Greene climacteric scales. Reduction on the MenQoL scale between first and last visit was from 4.31 to 3.27 (p<0.001) and on the Green climacteric scale from 21.01 to 13.00 (p<0.001). Study participants did not reliably complete their flushing diaries. No adverse events or abnormal liver or kidney function values were observed during the course of the study.
  
  
  CONCLUSIONS
  Further research that seeks to investigate the effects observed in more detail and to evaluate them against other forms of treatment and/or no-treatment controls is warranted. This could be achieved by way of a pragmatic randomized controlled trial that evaluated Chinese medicine against orthodox medical care.
authors.affiliation: EASTmedicine, Faculty of Science and Technology, University of Westminster, 115 New Cavendish Street, London W1W 6UW, United Kingdom. Electronic address: scheidv@wmin.ac.uk.
authors.forename: Volker
authors.initials: V
authors.lastname: Scheid
authors.affiliation: Faculty of Science and Technology, University of Westminster, 115 New Cavendish Street, London W1W 6UW, United Kingdom. Electronic address: tuffrev@wmin.ac.uk.
authors.forename: Veronica
authors.initials: V
authors.lastname: Tuffrey
authors.affiliation: EASTmedicine, Faculty of Science and Technology, University of Westminster, 115 New Cavendish Street, London W1W 6UW, United Kingdom. Electronic address: thomas@innerqi.co.uk.
authors.forename: Thomas
authors.initials: T
authors.lastname: Weijburg
authors.affiliation: Faculty of Health and Social Care, London South Bank University, London SE1 0AA, United Kingdom. Electronic address: markb@acupuncture.org.uk.
authors.forename: Mark
authors.initials: M
authors.lastname: Bovey
authors.affiliation: EASTmedicine, Faculty of Science and Technology, University of Westminster, 115 New Cavendish Street, London W1W 6UW, United Kingdom. Electronic address: trinaward@gmail.com.
authors.forename: Trina
authors.initials: T
authors.lastname: Ward
mesh_terms: D015670:Acupuncture Therapy; D002986:Clinical Trials as Topic; D004035:Diet Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006296:Health Services; D019584:Hot Flashes / Q000628:therapy*; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008593:Menopause; D008875:Middle Aged; D010865:Pilot Projects; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D006113:United Kingdom
chemical_list: D004365:Drugs, Chinese Herbal
keywords: Acupuncture; Chinese medicine; Herbal medicine; Menopausal symptoms; Menopause; Personalized health care