title: The association of nutritional profile and prognosis of degenerative diseases associated with carbohydrate and lipid metabolism at high altitude of district Ziarat, Pakistan.
abstract: OBJECTIVE
  In the present study the physiological parameters, their comparative analysis with carbohydrate and lipid metabolism were studied. This study suggests life style, environmental and genetic adaptations in the studied population.
  
  
  METHODS
  One hundred and ninety eight subjects were selected from different towns of District Ziarat. General characteristics of the population according to their nutritional habits including, age, body mass index(BMI), systolic blood pressure, diastolic blood pressure, glycemia, triglycerides, serum low density lipoprotein (LDL), high density lipoprotein (HDL), very low density lipoprotein (VLDL), triglycerides (TG) were measured.
  
  
  RESULTS
  Mean cholesterol, LDL, VLDL and triglyceride values were significantly higher in men than women and the values increased with increasing age in both men and women. HDL and glucose values were significantly higher in females than males. In men with various nutritional groups such as A, B and C, the mean cholesterol (P < 0.001), LDL (P < 0.014), VLDL (P < 0.031) and triglyceride (P < 0.025) levels were significantly observed among comparable groups. However, in women with various nutritional groups such as A, B and C, the mean age (P < 0.047) and triglyceride values (P < 0.033) display statistically significant results.
authors.affiliation: Government Degree College, Quetta, Pakistan ; Department of Biotechnology and Informatics, BUITEMS, Quetta, Pakistan.
authors.forename: Sultan Ahmad
authors.initials: SA
authors.lastname: Baig
authors.affiliation: Department of Biotechnology and Informatics, BUITEMS, Quetta, Pakistan ; Office of Research Innovation and Commercialization, BUITEMS, Quetta, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Asif
authors.affiliation: Government Degree College, Quetta, Pakistan ; Department of Biotechnology and Informatics, BUITEMS, Quetta, Pakistan.
authors.forename: Tahir Mahmood
authors.initials: TM
authors.lastname: Irfani
authors.affiliation: Department of Biotechnology and Informatics, BUITEMS, Quetta, Pakistan.
authors.forename: Abrar
authors.initials: A
authors.lastname: Hussain
authors.affiliation: Department of Biotechnology and Informatics, BUITEMS, Quetta, Pakistan ; Institute of Molecular Biology & Biotechnology (IMBB), The University of Lahore, Pakistan.
authors.forename: Abdul Majeed
authors.initials: AM
authors.lastname: Cheema
authors.affiliation: Institute of Molecular Biology & Biotechnology (IMBB), The University of Lahore, Pakistan.
authors.forename: Arif
authors.initials: A
authors.lastname: Malik
authors.affiliation: King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: Mohammad Amjad
authors.initials: MA
authors.lastname: Kamal
authors.affiliation: Center of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Rasool
keywords: Altitude; Degenerative diseases; Nutritional profile