title: Relation of age and sex with carotid intima media thickness in healthy children.
abstract: OBJECTIVE
  To investigate the age- and sex-associated carotid intima media thickness (clMT) changes in healthy children to determine the age- and sex-specific normal range of values for childhood.
  
  
  METHODS
  This study examined 91 healthy school-age children aged 7-15 years prospectively. Standardized sonographic cIMT measurements and analyses were performed. Body mass index and blood pressure were obtained, and atherosclerotic risk factors were investigated. Age- and sex-specific cIMT measurements for different age groups were calculated and the relation with sex was investigated.
  
  
  RESULTS
  Regarding the total study group, mean cIMT measurements for age groups 7-9, 10-12, and 13-15 years were 4.1 + 0.5 mm, 4.4 ± 0.6 mm, and 4.6 ± 0.4 mm, respectively. cIMT did not differ between boys and girls in the same age group. Age related analyses showed significant variations among the age groups with positive correlation between cIMT and age.
  
  
  CONCLUSIONS
  Our results suggest that age-related physiologic thickening of the carotid artery intima-media occurs not only in adults but also in children and that sex is not a factor for cIMT differences in childhood.
authors.affiliation: Department of Radiology, Pamukkale University, Denizli, Turkey. alkoc@yahoo.com
authors.forename: Ali
authors.initials: A
authors.lastname: Koçyiğit
authors.forename: Mustafa
authors.initials: M
authors.lastname: Doğan
authors.forename: İsmail
authors.initials: İ
authors.lastname: Yilmaz
authors.forename: Murat
authors.initials: M
authors.lastname: Çağlar
authors.forename: Celile
authors.initials: C
authors.lastname: Hatipoğlu
authors.forename: Figen
authors.initials: F
authors.lastname: Koçyiğit
authors.forename: Duygu
authors.initials: D
authors.lastname: Herek
authors.forename: Nevzat
authors.initials: N
authors.lastname: Karabulut
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002339:Carotid Arteries / Q000000981:diagnostic imaging*; D059168:Carotid Intima-Media Thickness; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D012737:Sex Factors