title: The 'emergence' of turnip mosaic virus was probably a 'gene-for-quasi-gene' event.
abstract: Turnip mosaic potyvirus is a virus of brassicas that emerged from a lineage of monocotyledon-infecting potyviruses about 1000 years ago. In vivo and in silico studies all indicate that sites, primarily in its protein 3 (P3) and cylindrical inclusion protein (CI) genes, but also its small 6 kDa 2 protein (6K2) and genome-linked viral protein (VPg) genes, control host specificity in a dynamic way. It is most likely that non-unique combinations of transient viral genomic single nucleotide polymorphisms (SNPs), not all of them non-synonymous, allowed the host switch to occur. These SNPs were probably ephemeral and replaced over time by other combinations as the population subsequently diverged within, and adapted to, the brassica host population.
authors.affiliation: Australian National University Emeritus Faculty, Canberra, ACT 2601, Australia. Electronic address: adrian_j_gibbs@hotmail.com.
authors.forename: Adrian J
authors.initials: AJ
authors.lastname: Gibbs
authors.affiliation: Laboratory of Plant Virology, Faculty of Agriculture, Saga University, Saga 840-8502, Japan; Department of Plant Pathology, Faculty of Agronomy, Vietnam National University of Agriculture, Trauquy, Gialam, Hanoi, Viet Nam.
authors.forename: Huy Duc
authors.initials: HD
authors.lastname: Nguyen
authors.affiliation: Laboratory of Plant Virology, Faculty of Agriculture, Saga University, Saga 840-8502, Japan.
authors.forename: Kazusato
authors.initials: K
authors.lastname: Ohshima
mesh_terms: D001937:Brassica / Q000821:virology*; D029688:Brassica napus / Q000821:virology; D003198:Computer Simulation; D016679:Genome, Viral; D058507:Host Specificity / Q000235:genetics*; D010935:Plant Diseases / Q000821:virology*; D020641:Polymorphism, Single Nucleotide; D017800:Potyvirus / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics / Q000378:metabolism
chemical_list: D012367:RNA, Viral