title: Evaluation of liver injury in a tertiary hospital: a retrospective study.
abstract: BACKGROUND
  Liver is the most frequently injured intraabdominal organ following abdominal trauma. Liver injury in polytraumatized patients can vary from minor contusions to major lacerations and is associated with morbidity and mortality. The objective of this study was to evaluate the outcome of liver injury in polytraumatized patients.
  
  
  METHODS
  Only surgically treated 82 patients with liver injury over an eight year period (2005-2013) were included in this study and analyzed retrospectively. Data collected included demographics, laboratory findings, intraoperative findings, operative management, and outcome. The patients were divided into two groups and the mortality and survival data were compared.
  
  
  RESULTS
  The overall mortality rate was 18.3% (15 of 82 patients). 34 (41.5%) patients had blunt, forty-eight (48.5%) had penetrating trauma. There were multiple traumas in forty-seven (57%) patients. Forty-seven (57%) patients had total of seventy one coexisting intraabdominal injuries. Forty-six (56.1%) patients had stable and thirty-six (43.9%) had unstable hemodynamics on admission. In mortality group AST, ALT, LDH, APTT, PT, INR, and creatinine levels were high, fibrinogen levels and platelet counts were low on admission.
  
  
  CONCLUSIONS
  Hemodynamic instability, coexisting musculoskeletal and chest injury, high APTT, PT, INR, AST, ALT, LDH levels, and low fibrinogen levels and platelet counts on admission should be considered as predictive factors for mortality.
authors.affiliation: Department of General Surgery, Ankara Numune Training and Research Hospital, Ankara, Turkey. drismailbilgic@gmail.com.
authors.forename: İsmail
authors.initials: İ
authors.lastname: Bilgiç
authors.affiliation: Department of General Surgery, Ankara Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Sibel
authors.initials: S
authors.lastname: Gelecek
authors.affiliation: Department of General Surgery, Ankara Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Ali Emre
authors.initials: AE
authors.lastname: Akgün
authors.affiliation: Department of General Surgery, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors.forename: Mehmet Mahir
authors.initials: MM
authors.lastname: Özmen
mesh_terms: D000007:Abdominal Injuries / Q000453:epidemiology* / Q000401:mortality / Q000601:surgery; D000328:Adult; D005260:Female; D006801:Humans; D015601:Injury Severity Score; D008099:Liver / Q000293:injuries* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000453:epidemiology / Q000401:mortality / Q000601:surgery; D012189:Retrospective Studies; D012737:Sex Factors; D062606:Tertiary Care Centers / Q000706:statistics & numerical data*; D013898:Thoracic Injuries / Q000453:epidemiology* / Q000401:mortality / Q000601:surgery; D014421:Turkey / Q000453:epidemiology; D014949:Wounds, Nonpenetrating / Q000453:epidemiology / Q000401:mortality / Q000601:surgery; D014950:Wounds, Penetrating / Q000453:epidemiology / Q000401:mortality / Q000601:surgery; D055815:Young Adult