title: Trends in age-specific cerebrovascular disease in the European Union.
abstract: Although the mortality of cerebrovascular disease (CVD) has been steadily declined in the European Union (EU), CVD remains among the major causes of death in EU. As risk factors such asobesity and diabetes mellitus are increasing, the trends of European CVD mortality remains unknown. To understand the variation in CVD mortality of different EU countries, we studied the trends in CVD mortality in EU countries over the last three decades between males and females. Age- and sex-specific mortality rates between 1980 and 2011 were calculated by data from the WHO mortality database. Joinpoint software was used to calculate annual percentage changes and to characterize trends in mortality rates over time. Our study showed that between 1980 and 2011, CVD mortality significantly decreased in both men and women across all age groups. The specific mortality trends varied largely between EU countries. The plateau trend was observed in little regions at different age groups, however, the EU as a whole displayed declined trend CVD mortality. During the last three decades, CVD mortality decreased substantially in the entire population of EU. However, despite this overall decline in CVD mortality, several areas were identified as having no change in their CVD mortality rates at different period. The whole EU needs to establish strict prevention measures toreduce the incidence of CVD risk factors.
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Sun
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China.
authors.forename: Yue
authors.initials: Y
authors.lastname: Ji
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Shi
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China.
authors.forename: Qinkao
authors.initials: Q
authors.lastname: Xuan
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China.
authors.forename: Xiuzhi
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China ; Regeneration Lab, School of Life Science, Shanghai University Shanghai 200444, China.
authors.forename: Junjie
authors.initials: J
authors.lastname: Xiao
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University Nanjing 210029, China.
authors.forename: Xiangqing
authors.initials: X
authors.lastname: Kong
keywords: Cerebrovascular disease; mortality; trends