title: Synthetic polyglycomer short-term absorbable sutures vs. polydioxanone long-term absorbable sutures for preventing incisional hernia and wound dehiscence after abdominal wall closure: a comparative randomized study of patients treated for gastric or colon cancer.
abstract: OBJECTIVE
  To compare the results of abdominal wall closure using interrupted synthetic short-term vs. long-term tensile strength-retaining absorbable sutures.
  
  
  METHODS
  The subjects were 55 patients undergoing elective laparotomy through a midline vertical incision for gastric or colon cancer surgery between November 2008 and August 2010, at our hospital. After providing informed consent, the patients were randomized for suturing with Polysorb(®), which provides short-term tensile strength, or with PDS(®)II, which provides long-term strength. The primary outcome analyzed was the incidence of incisional hernia or wound dehiscence.
  
  
  RESULTS
  There were 28 patients allocated to the Polysorb group and 27 to the PDS II group. Postoperative wound dehiscence was noted in two patients (3.6%). Five of 51 patients (9.8%) suffered incisional hernia within 1 year after surgery, 6 of 41 patients (14.6%) within 2 years, and 6 of 35 patients (17.1%) within 3 years. There was no significant per year difference in the incidence of incisional hernia or wound dehiscence between the groups.
  
  
  CONCLUSIONS
  Outcomes were favorable in both groups and not inferior to reported outcomes of larger-scale studies. Verification of the equivalence between the two types of suture material necessitates larger-scale studies that adopt the same suture methods.
authors.affiliation: Department of Frontier Surgery Graduate School of Medicine, Chiba University, Chiba, Japan.
authors.forename: Gaku
authors.initials: G
authors.lastname: Ohira
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kawahira
authors.forename: Hideaki
authors.initials: H
authors.lastname: Miyauchi
authors.forename: Kazufumi
authors.initials: K
authors.lastname: Suzuki
authors.forename: Takanori
authors.initials: T
authors.lastname: Nishimori
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Hanari
authors.forename: Mikito
authors.initials: M
authors.lastname: Mori
authors.forename: Takayuki
authors.initials: T
authors.lastname: Tohma
authors.forename: Hisashi
authors.initials: H
authors.lastname: Gunji
authors.forename: Daisuke
authors.initials: D
authors.lastname: Horibe
authors.forename: Kazuo
authors.initials: K
authors.lastname: Narushima
authors.forename: Hisahiro
authors.initials: H
authors.lastname: Matsubara
mesh_terms: D058107:Abdominal Wound Closure Techniques / Q000295:instrumentation*; D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000601:surgery; D017558:Elective Surgical Procedures; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D000069290:Incisional Hernia / Q000453:epidemiology / Q000517:prevention & control*; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D016687:Polydioxanone; D011108:Polymers; D011446:Prospective Studies; D013274:Stomach Neoplasms / Q000601:surgery; D013529:Surgical Wound Dehiscence / Q000453:epidemiology / Q000517:prevention & control*; D013537:Sutures; D016896:Treatment Outcome
chemical_list: D011108:Polymers; C048851:polysorb; D016687:Polydioxanone