title: Recovery of photoreceptor layer on spectral-domain optical coherence tomography after vitreous surgery combined with air tamponade in chronic idiopathic macular hole.
abstract: OBJECTIVE
  Studies using sterilized air in chronic idiopathic macular holes show varying success rates, and the impact of a shorter duration of tamponade on photoreceptor layer recovery is not fully elucidated.
  
  
  METHODS
  Surgical outcomes of 35 cases (seven in stage 3 and 28 in stage 4) were assessed for best corrected visual acuity and with spectral-domain optical coherence tomography.
  
  
  RESULTS
  The primary closure rate was 91.4%, and the closed cases and unclosed cases were significantly different in the preoperative (P = .042) and postoperative (P = .040) diameter of the photoreceptor layer defect. After surgery, there was a significant improvement in best corrected visual acuity and a decrease in the photoreceptor layer defect. The postoperative logarithm of the minimal angle of resolution was significantly correlated with the preoperative hole diameter (P = .003) and the postoperative diameter of the photoreceptor layer defect (P = .005).
  
  
  CONCLUSIONS
  Air tamponade is a safe and effective treatment for chronic and severe macular holes, with several spectral-domain optical coherence tomography parameters highly predictive of postoperative visual acuity.
authors.forename: Feng
authors.initials: F
authors.lastname: He
authors.forename: Fangtian
authors.initials: F
authors.lastname: Dong
authors.forename: Weihong
authors.initials: W
authors.lastname: Yu
authors.forename: Rongping
authors.initials: R
authors.lastname: Dai
mesh_terms: D000328:Adult; D000368:Aged; D000388:Air; D002908:Chronic Disease; D003131:Combined Modality Therapy; D058450:Endotamponade / Q000379:methods*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D020419:Photoreceptor Cells, Vertebrate / Q000502:physiology*; D016684:Prone Position; D020127:Recovery of Function / Q000502:physiology; D012167:Retinal Perforations / Q000145:classification / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology*; D014821:Vitrectomy / Q000379:methods*