title: [Imaging Moya-Moya disease].
abstract: Moya-Moya disease is a rare arterial occlusive disease affecting the internal carotid artery and its branches. It is found in both pediatric and adult populations, and it may lead to severe clinical presentations such as stroke and intracranial hemorrhage. Several surgical procedures have been developed to improve its clinical outcome. Imaging techniques have a key role in management of Moya-Moya disease, as they are necessary for diagnosis, choice of treatment and follow-up. Although catheter angiography remains the diagnostic gold standard, and nuclear-medicine techniques best perform hemodynamic studies, less invasive imaging techniques have become efficient in serving these purposes. Conventional MRI and MR angiography, as well as MR functional and metabolic studies, are now widely used in each stage of disease management, from diagnosis to follow-up. CT scan and Doppler sonography may also help assess severity of disease and effects of treatment. The aim of this review is to clarify the utility, efficiency and latest developments of each imaging modality in management of Moya-Moya disease.
authors.affiliation: Service de radiologie pédiatrique, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France; Faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Ancelet
authors.affiliation: Service de radiologie pédiatrique, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France; Faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Inserm UMR 894, centre de psychiatrie et neurosciences, faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neuroradiologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France.
authors.forename: G
authors.initials: G
authors.lastname: Boulouis
authors.affiliation: Service de radiologie pédiatrique, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France; Service de neurochirurgie, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France.
authors.forename: T
authors.initials: T
authors.lastname: Blauwblomme
authors.affiliation: Faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neurologie pédiatrique, Centre national de référence de l'AVC de l'enfant, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Kossorotoff
authors.affiliation: Inserm UMR 894, centre de psychiatrie et neurosciences, faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neuroradiologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Rodriguez-Regent
authors.affiliation: Inserm UMR 894, centre de psychiatrie et neurosciences, faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neuroradiologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Mellerio
authors.affiliation: Service de radiologie pédiatrique, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Grevent
authors.affiliation: Inserm UMR 894, centre de psychiatrie et neurosciences, faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neuroradiologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France.
authors.forename: J-F
authors.initials: JF
authors.lastname: Meder
authors.affiliation: Inserm UMR 894, centre de psychiatrie et neurosciences, faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neuroradiologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Trystram
authors.affiliation: Inserm UMR 894, centre de psychiatrie et neurosciences, faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neuroradiologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Oppenheim
authors.affiliation: Faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neurochirurgie, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Zerah
authors.affiliation: Faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neurochirurgie, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Puget
authors.affiliation: Faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neurochirurgie, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Sainte-Rose
authors.affiliation: Service de radiologie pédiatrique, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Boddaert
authors.affiliation: Service de radiologie pédiatrique, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Brunelle
authors.affiliation: Service de radiologie pédiatrique, hôpital Necker-Enfants-Malades, rue de Sèvres, 75007 Paris, France; Faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Inserm UMR 894, centre de psychiatrie et neurosciences, faculté de médecine, université Paris Descartes, Sorbonne Paris Cité, 15, rue de l'École-de-Médecine, 75006 Paris, France; Service de neuroradiologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France. Electronic address: o.naggara@ch-sainte-anne.fr.
authors.forename: O
authors.initials: O
authors.lastname: Naggara
mesh_terms: D000328:Adult; D002533:Cerebral Angiography / Q000379:methods; D003952:Diagnostic Imaging / Q000379:methods*; D004453:Echoencephalography / Q000379:methods; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods; D009072:Moyamoya Disease / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed / Q000379:methods; D018608:Ultrasonography, Doppler; D062666:Vascular Access Devices
keywords: Cerebral revascularization; Diagnostic; Diagnostic imaging; Imagerie de perfusion; Imagerie par résonance magnétique; Magnetic resonance imaging; Maladie de Moya-Moya; Moya-Moya disease; Perfusion imaging; Revascularisation cérébrale