title: Changes in preterm human milk composition with particular reference to introduction of mixed feeding.
abstract: OBJECTIVE
  To study the changes in composition of preterm milk till 6 months of age.
  
  
  METHODS
  Milk samples from 33, 19, 7 and 12 lactating mothers (delivered <34 weeks) were analyzed on days 7, 28, 90 and 180, respectively.
  
  
  RESULTS
  Triglyceride and sodium concentrations increased significantly with time and protein concentration decreased significantly over 180 days. Sodium (P=0.02) and triglyceride concentrations (P=0.06) were higher in milk samples of mothers who had introduced mixed feeding by 6 months post natal age (n=6) compared to exclusively breast-feeding mothers (n=6); but lactose and protein content was not significantly different.
  
  
  CONCLUSIONS
  Milk of preterm mothers has higher amount of triglycerides and sodium during introduction of mixed feeding.
authors.affiliation: Division of Neonatology, Department of Pediatrics; and *Department of Biochemistry, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. Correspondence to: Dr Sourabh Dutta, Additional Professor, Division of Neonatology, Advanced Pediatric Centre, PGIMER, Chandigarh 160 012, India. sourabhdutta1@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Dutta
authors.forename: S
authors.initials: S
authors.lastname: Saini
authors.forename: R
authors.initials: R
authors.lastname: Prasad
mesh_terms: D001942:Breast Feeding; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007774:Lactation / Q000502:physiology*; D008137:Longitudinal Studies; D008894:Milk Proteins / Q000032:analysis / Q000378:metabolism; D008895:Milk, Human / Q000737:chemistry* / Q000378:metabolism; D012964:Sodium / Q000032:analysis / Q000378:metabolism; D014280:Triglycerides / Q000032:analysis / Q000378:metabolism
chemical_list: D008894:Milk Proteins; D014280:Triglycerides; D012964:Sodium