title: Role of PET/CT in the diagnosis, staging, and follow-up of a nasal-type natural killer T-cell lymphoma in the larynx: a case report and literature review.
abstract: BACKGROUND
  Nasal-type natural killer T-cell lymphoma involving the larynx is uncommon. Our search revealed only 12 cases reported previously in the English-language literature.
  
  
  METHODS
  We report a case of laryngeal NKTCL. In December 2011, the patient was diagnosed with nasal-type NKTCL and FDG PET/CT showed the lesions were confined to the nasal cavity (stage I). At 1 year after radiotherapy, the patient presented with hoarseness and FDG PET/CT revealed high FDG uptake in the subglottic region and left cervical lymph nodes. A biopsy of the subglottis confirmed NKTCL (stage II). He then received chemotherapy and 14 months after the completion of chemotherapy, FDG PET/CT showed no evidence of recurrence or metastasis.
  
  
  CONCLUSIONS
  PET/CT has better sensitivity than other conventional methods and may play an important role in the diagnosis, staging, and follow-up of nasal-type natural killer T-cell lymphoma.
authors.affiliation: Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University 310003, China.
authors.forename: Min-Li
authors.initials: ML
authors.lastname: Zhou
authors.affiliation: Department of PET/CT Centre, The First Affiliated Hospital, College of Medicine, Zhejiang University 310003, China.
authors.forename: Kui
authors.initials: K
authors.lastname: Zhao
authors.affiliation: Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University 310003, China.
authors.forename: Shui-Hong
authors.initials: SH
authors.lastname: Zhou
authors.affiliation: Department of Otolaryngology, The First Affiliated Hospital, College of Medicine, Zhejiang University 310003, China.
authors.forename: Qin-Ying
authors.initials: QY
authors.lastname: Wang
authors.affiliation: Department of Pathology, The First Affiliated Hospital, College of Medicine, Zhejiang University 310003, China.
authors.forename: Zhou-Jun
authors.initials: ZJ
authors.lastname: Zheng
authors.affiliation: Department of Radiotherapy, The First Affiliated Hospital, College of Medicine, Zhejiang University 310003, China.
authors.forename: Zhong-Jie
authors.initials: ZJ
authors.lastname: Lu
keywords: Natural killer T-cell lymphoma; PET/CT; follow-up; larynx