title: Comparison of cerebral-cardiac syndrome caused by nonaneurysmal or aneurysmal subarachnoid hemorrhage.
abstract: OBJECTIVE
  To investigate the difference between myocardial injuries caused by nonaneurysmal subarachnoid hemorrhage (SAH) or aneurysmal SAH.
  
  
  METHODS
  A total of 92 inpatients with SAH at early stage (within 48h), who were treated in our hospital from 2008 to 2014 were enrolled in this study. Differences in cerebral-cardiac syndrome seen in perimesencephalic subarachnoid hemorrhage (PMSAH), non-perimesencephalic subarachnoid hemorrhage (n-PMSAH), and aneurysmal subarachnoid hemorrhage (aSAH) were recorded based Hunt-Hess scores, electrocardiogram/echocardiography findings, and serum myocardial enzymes.
  
  
  RESULTS
  The Hunt-Hess grade was relatively lower in the PMSAH group (mainly at grades I and II) than in aSAH group and n-PMSAH group. The ECG score was significantly lower in the PMSAH Group than in the aSAH or n-PMSAH Group. In the PMSAH group, the left ventricular function was normal; in contrast, the left ventricular end-systolic diameter, left ventricular end-diastolic diameter, left ventricular wall thickness, and left ventricular ejection fraction showed certain abnormalities in the aSAH group and n-PMSAH group. The myocardial enzymes remarkably increased only in the aSAH group.
  
  
  CONCLUSIONS
  In PMSAH patients, the lower Hunt-Hess grade, milder ECG abnormalities, less changes in cardiac enzymes and echocardiography are associated with better prognosis. The clinical course and myocardial injuries are poorer in n-PMSAH patients when compared with the PMSAH patients but better than aSAH patients.
authors.affiliation: Department of Neurology, Xuzhou Central Hospital, Xuzhou, Jiangsu Province, China. baogaozx@163.com.
authors.forename: W-J
authors.initials: WJ
authors.lastname: Huang
authors.forename: W-W
authors.initials: WW
authors.lastname: Chen
authors.forename: X
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology*; D004562:Electrocardiography / Q000379:methods; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume / Q000502:physiology; D013345:Subarachnoid Hemorrhage / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*; D013577:Syndrome; D016277:Ventricular Function, Left / Q000502:physiology