title: Senescence helps regeneration.
abstract: Cellular senescence is a response to damage that involves inflammation and extracellular matrix remodeling and that resolves with the phagocytic elimination of the senescent cells. Demaria et al. (2014) in this issue of Developmental Cell demonstrate that cellular senescence plays an active and positive role during tissue regeneration.
authors.affiliation: Spanish National Cancer Research Center (CNIO), 28029 Madrid, Spain. Electronic address: mserrano@cnio.es.
authors.forename: Manuel
authors.initials: M
authors.lastname: Serrano
mesh_terms: D000818:Animals; D016922:Cellular Senescence; D042783:Endothelial Cells / Q000166:cytology*; D005260:Female; D008297:Male; D008648:Mesoderm / Q000166:cytology*; D010982:Platelet-Derived Growth Factor / Q000378:metabolism*; D014945:Wound Healing
chemical_list: D010982:Platelet-Derived Growth Factor; C075278:platelet-derived growth factor A