title: Visualization of vascular structure of spinal hemangioblastoma using intraoperative indocyanine green videoangiography and temporary feeder occlusion.
abstract: OBJECTIVE
  To more safely resect pathological lesions during spinal vascular lesion surgery, it is most important to understand local abnormal hemodynamics in detail. New devices or techniques that make out intraoperative local hemodynamics have been awaited. To introduce a resourceful method, we present a case of spinal hemangioblastoma for which temporary arterial occlusion during near-infrared intraoperative indocyanine green (ICG) videoangiography gives useful assessment of the main and minor feeders easily.
  
  
  METHODS
  A 36-year-old female suffered progressive paresthesia of both lower extremities for 12 months and gait disturbance for 2 weeks. A neurological examination revealed T10 myelopathy. Magnetic resonance imaging (MRI) of the thoracic spine showed an intramedullary tumor at the T8 level and severe spinal cord edema with a flow void in the extended dorsal spinal veins. Spinal angiography showed a hemangioblastoma at the T8 level, with two main feeders and minor feeders.
  
  
  RESULTS
  She underwent total resection of the tumor by a posterior approach. During the intraoperative ICG videoangiography, temporary arterial occlusion of the two main feeders and FLOW(®)800 analysis enabled clear understanding of the vasculature, especially of the two minor feeders. At the 9-month follow-up, her neurological manifestation was partially resolved, and post-operative MRI showed total removal of the tumor and disappearance of the spinal cord edema.
  
  
  CONCLUSIONS
  Temporary clipping of the main feeders during intraoperative ICG videoangiography is very useful for easily determining the minor feeding arteries, and helpful for maintaining normal perfusion of the spinal cord in spinal hemangioblastoma surgery. Furthermore, the FLOW 800 analysis, especially the false color-coded variation, increased our understanding of the hemodynamics.
authors.affiliation: Department of Neurosurgery, Nara Medical University School of Medicine, 840 Shijo-cho, Kashihara, Nara, 634-8521, Japan, takeshim@naramed-u.ac.jp.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Takeshima
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Hironaka
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Shida
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakase
mesh_terms: D000328:Adult; D005260:Female; D018325:Hemangioblastoma / Q000098:blood supply* / Q000601:surgery; D006801:Humans; D007208:Indocyanine Green; D007430:Intraoperative Care / Q000379:methods; D008279:Magnetic Resonance Imaging; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging* / Q000601:surgery; D019635:Neurosurgical Procedures / Q000379:methods; D015641:Radiography, Interventional / Q000379:methods; D013118:Spinal Cord Diseases / Q000601:surgery; D013120:Spinal Cord Neoplasms / Q000098:blood supply* / Q000601:surgery; D014656:Vascular Surgical Procedures; D020535:Video-Assisted Surgery / Q000379:methods
chemical_list: D007208:Indocyanine Green