title: [Apropos of 5 cases of optic nerve tumors diagnosed during a 6-year-period].
abstract: BACKGROUND
  Optic nerve tumors are uncommon and rarely described. By way of five patients treated at the University Hospital of Clermont-Ferrand, France, over a six-year-period, we discuss their clinical and radiological characteristics, their treatment and their course.
  
  
  METHODS
  We report two cases of optic nerve glioma in small children, two cases of optic nerve sheath meningioma and a 57-year-old patient treated for lung cancer with an optic nerve metastasis and choroidal and brain metastases. The diagnosis was confirmed by imaging in all patients and histologically for the cases of optic nerve glioma.
  
  
  RESULTS
  The children with glioma were exclusively treated with chemotherapy, the two women with meningioma exclusively with radiation therapy, and the man with the optic nerve metastasis by chemotherapy and radiotherapy. The tumors were stabilized in all cases except for a progression in one case of glioma, one year after treatment.
  
  
  CONCLUSIONS
  Gliomas and meningiomas are the most frequent tumors; other tumors are rare. Through a literature review and many illustrations, we discuss epidemiologic, clinical and radiologic characteristics, treatment and course of these uncommon tumors.
  
  
  CONCLUSIONS
  The diagnosis of optic nerve tumors must be considered in cases of anterior or posterior progressive optic neuropathy. Treatment must be a compromise between effective treatment of the tumor and preservation of visual function. Decisions are made through multidisciplinary consultations, in which the role of the ophthalmologist is crucial for the diagnosis and success of the treatment.
authors.affiliation: Pôle médecine interne-ophtalmologie-ORL, service d'ophtalmologie, CHU de Clermont-Ferrand, 63003 Clermont-Ferrand, France. Electronic address: srebika@chu-clermontferrand.fr.
authors.forename: S
authors.initials: S
authors.lastname: Rebika
authors.affiliation: Pôle médecine interne-ophtalmologie-ORL, service d'ophtalmologie, CHU de Clermont-Ferrand, 63003 Clermont-Ferrand, France.
authors.forename: N
authors.initials: N
authors.lastname: Bonnin
authors.affiliation: Centre de biochimie, service anatomopathologie, de CHU Clermont-Ferrand, 63003 Clermont-Ferrand, France.
authors.forename: J-L
authors.initials: JL
authors.lastname: Kémény
authors.affiliation: Pôle médecine interne-ophtalmologie-ORL, service d'ophtalmologie, CHU de Clermont-Ferrand, 63003 Clermont-Ferrand, France.
authors.forename: F
authors.initials: F
authors.lastname: Chiambaretta
authors.affiliation: Pôle médecine interne-ophtalmologie-ORL, service d'ophtalmologie, CHU de Clermont-Ferrand, 63003 Clermont-Ferrand, France.
authors.forename: F
authors.initials: F
authors.lastname: Bacin
mesh_terms: D017668:Age of Onset; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D002283:Carcinoma, Bronchogenic / Q000532:radiotherapy / Q000556:secondary; D005094:Exophthalmos / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D008875:Middle Aged; D018317:Nerve Sheath Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D020339:Optic Nerve Glioma / Q000150:complications / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D019574:Optic Nerve Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000556:secondary / Q000628:therapy; D010348:Patient Care Team; D016634:Radiosurgery; D012189:Retrospective Studies; D016896:Treatment Outcome; D058609:Visual Field Tests
keywords: Glioma; Gliome; Meningioma; Metastasis; Méningiome; Métastase; Optic nerve neoplasms; Tumeurs du nerf optique