title: [Histomorphometric charactheristic of skeletal muscle regenerating after a closed partial crush injury].
abstract: To evaluate the degree of skeletal muscle regeneration in 15 adult Wistar rats, the closed partial crush injury of anterior tibial muscle was modeled. The study was performed using the methods of light microscopy and computer-assisted morphometry of semithin sections. The continuity of the crushed muscle fibres (MF) was restored by day 21 after the injury. After 90 days endomysial fibrosis was substantially reduced and its vasculairity increased; the variability of MF diameters was restored, however the branched structure and myopathic changes of the regenerated tissue persisted and were presumably associated with an incomplete reinnervation of the damaged intramuscular nerves.
authors.forename: N A
authors.initials: NA
authors.lastname: Shchudlo
authors.forename: M M
authors.initials: MM
authors.lastname: Shchudlo
authors.forename: N A
authors.initials: NA
authors.lastname: Kononovich
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D008297:Male; D018482:Muscle, Skeletal / Q000293:injuries* / Q000473:pathology / Q000503:physiopathology*; D009135:Muscular Diseases / Q000473:pathology / Q000503:physiopathology*; D051381:Rats; D017208:Rats, Wistar; D012038:Regeneration