title: The impact of short duration, high intensity exercise on cardiac troponin release.
abstract: The aim of this study was to assess the appearance of cardiac troponins (cTnI and/or cTnT) after a short bout (30 s) of 'all-out' intense exercise and to determine the stability of any exercise-related cTnI release in response to repeated bouts of high intensity exercise separated by 7 days recovery. Eighteen apparently healthy, physically active, male university students completed two all-out 30 s cycle sprint, separated by 7 days. cTnI, blood lactate and catecholamine concentrations were measured before, immediately after and 24 h after each bout. Cycle performance, heart rate and blood pressure responses to exercise were also recorded. Cycle performance was modestly elevated in the second trial [6·5% increase in peak power output (PPO)]; there was no difference in the cardiovascular, lactate or catecholamine response to the two cycle trials. cTnI was not significantly elevated from baseline through recovery (Trial 1: 0·06 ± 0·04 ng ml(-1) , 0·05 ± 0·04 ng ml(-1) , 0·03 ± 0·02 ng ml(-1) ; Trial 2: 0·02 ± 0·04 ng ml(-1) , 0·04 ± 0·03 ng ml(-1) , 0·05 ± 0·06 ng ml(-1) ) in either trial. Very small within subject changes were not significantly correlated between the two trials (r = 0·06; P>0·05). Subsequently, short duration, high intensity exercise does not elicit a clinically relevant response in cTnI and any small alterations likely reflect the underlying biological variability of cTnI measurement within the participants.
authors.affiliation: Research Institute for Sport and Exercise Sciences, School of Sport and Exercise Sciences, Liverpool John Moores, Liverpool, UK.
authors.forename: Keith P
authors.initials: KP
authors.lastname: George
authors.affiliation: Faculty of Science and Technology, Exercise Science Research Laboratory, Institute of Clinical Exercise and Health Science, School of Science, University of the West of Scotland, Hamilton, UK.|Division of Sport and Exercise Sciences, School of Social & Health Sciences, Abertay University, Dundee, UK.
authors.forename: Marie Clare
authors.initials: MC
authors.lastname: Grant
authors.affiliation: Faculty of Life Sciences and Education, Sport, Health and Exercise Science Research Unit, University of South Wales, Treeforest, UK.
authors.forename: Bruce
authors.initials: B
authors.lastname: Davies
authors.affiliation: Faculty of Science and Technology, Exercise Science Research Laboratory, Institute of Clinical Exercise and Health Science, School of Science, University of the West of Scotland, Hamilton, UK.
authors.forename: Julien S
authors.initials: JS
authors.lastname: Baker
mesh_terms: D000328:Adult; D001642:Bicycling; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure; D002395:Catecholamines / Q000097:blood; D006339:Heart Rate; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D008297:Male; D009119:Muscle Contraction; D053580:Muscle Strength; D009206:Myocardium / Q000378:metabolism*; D005082:Physical Exertion; D020127:Recovery of Function; D013997:Time Factors; D019210:Troponin I / Q000097:blood*; D020107:Troponin T / Q000097:blood*; D055815:Young Adult
chemical_list: D015415:Biomarkers; D002395:Catecholamines; D019210:Troponin I; D020107:Troponin T; D019344:Lactic Acid
keywords: biological variability; cardiac biomarkers; cycle; fat free mass; total body mass