title: Extracorporeal worm extraction of Diphyllobothrium nihonkaiense with amidotrizoic acid in a child.
abstract: Infection cases of diphyllobothriid tapeworms are not much in the below teen-age group. We report a case of Diphyllobothrium nihonkaiense infection in a 13-year-old boy. He presented with severe fatigue, occasional abdominal pain at night time. He also had several episodes of tapeworm segment discharge in his stools. By his past history, he had frequently eaten raw fish including salmon and trout with his families. Numerous eggs of diphyllobothriid tapeworm were detected in the fecal examination. We introduced amidotrizoic acid as a cathartic agent through nasogastroduodenal tube and let nearly whole length (4.75 m) of D. nihonkaiense be excreted through his anus. After a single dose of praziquantel, the child's stool showed no further eggs, and his symptoms disappeared. The evacuated worm was identified as D. nihonkaiense by mitochondrial cox1 gene analysis. Here we report a successful extracorporeal worm extraction from an infection case of D. nihonkaiense by the injection of amidotrizoic acid.
authors.affiliation: Department of Pediatrics, Hanyang University College of Medicine, Seoul 133-792, Korea.
authors.forename: Hye Kyung
authors.initials: HK
authors.lastname: Shin
authors.affiliation: Department of Pediatrics, Hanyang University College of Medicine, Seoul 133-792, Korea.
authors.forename: Joo-Hyung
authors.initials: JH
authors.lastname: Roh
authors.affiliation: Department of Pediatrics, Hanyang University College of Medicine, Seoul 133-792, Korea.
authors.forename: Jae-Won
authors.initials: JW
authors.lastname: Oh
authors.affiliation: Department of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine, Seoul 133-792, Korea.
authors.forename: Jae-Sook
authors.initials: JS
authors.lastname: Ryu
authors.affiliation: Department of Parasitology and Tropical Medicine, Kyungpook National University School of Medicine, Daegu 700-422, Korea.
authors.forename: Youn-Kyoung
authors.initials: YK
authors.lastname: Goo
authors.affiliation: Department of Parasitology and Tropical Medicine, Kyungpook National University School of Medicine, Daegu 700-422, Korea.
authors.forename: Dong-Il
authors.initials: DI
authors.lastname: Chung
authors.affiliation: Department of Pediatrics, Hanyang University College of Medicine, Seoul 133-792, Korea.
authors.forename: Yong Joo
authors.initials: YJ
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000818:Animals; D000977:Antiparasitic Agents / Q000627:therapeutic use*; D051545:Cyclooxygenase 1 / Q000235:genetics; D003974:Diatrizoate Meglumine / Q000627:therapeutic use*; D004169:Diphyllobothriasis / Q000188:drug therapy* / Q000469:parasitology / Q000473:pathology; D004170:Diphyllobothrium / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification*; D005243:Feces / Q000469:parasitology; D006801:Humans; D008297:Male; D011223:Praziquantel / Q000627:therapeutic use; D017422:Sequence Analysis, DNA
chemical_list: D000977:Antiparasitic Agents; D003974:Diatrizoate Meglumine; D011223:Praziquantel; D051545:Cyclooxygenase 1
keywords: Diphyllobothrium nihonkaiense; amidotrizoic acid; child; cox1 gene