title: Silver-catalyzed arylation of (hetero)arenes by oxidative decarboxylation of aromatic carboxylic acids.
abstract: A long-standing challenge in Minisci reactions is achieving the arylation of heteroarenes by oxidative decarboxylation of aromatic carboxylic acids. To address this challenge, the silver-catalyzed intermolecular Minisci reaction of aromatic carboxylic acids was developed. With an inexpensive silver salt as a catalyst, this new reaction enables a variety of aromatic carboxylic acids to undergo decarboxylative coupling with electron-deficient arenes or heteroarenes regardless of the position of the substituents on the aromatic carboxylic acid, thus eliminating the need for ortho-substituted aromatic carboxylic acids, which were a limitation of previously reported methods.
authors.affiliation: State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Yangqiao West Road 155, Fuzhou, Fujian 350002 (China).
authors.forename: Jian
authors.initials: J
authors.lastname: Kan
authors.forename: Shijun
authors.initials: S
authors.lastname: Huang
authors.forename: Jin
authors.initials: J
authors.lastname: Lin
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.forename: Weiping
authors.initials: W
authors.lastname: Su
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D003653:Decarboxylation; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D010084:Oxidation-Reduction; D012834:Silver / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D006571:Heterocyclic Compounds; D006841:Hydrocarbons, Aromatic; D012834:Silver
keywords: CH activation; heterocycles; oxidation; radicals; silver