title: Ascomycotin A, a new citromycetin analogue produced by Ascomycota sp. Ind19F07 isolated from deep sea sediment.
abstract: A new citromycetin analogue, ascomycotin A (1), together with eight known compounds, wortmannilactone E (2), orcinol (3), orsellinic acid (4), isosclerone (5), (3R,4S)-( - )-4-hydroxymellein (6), diorcinol (7), chaetocyclinone B (8) and 2,5-dimethoxy-3,6-di(p-methoxypheny1)-1,4-benzoquinone (9), was isolated from the fungal strain Ascomycota sp. Ind19F07, which was isolated from the deep sea sediment of the Indian Ocean. The structures of the compounds were established by spectroscopic data including 1D and 2D NMR and HR-ESI-MS. Compounds (1-9) were evaluated for antibacterial activity.
authors.affiliation: a Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou 510301 , P.R. China.
authors.forename: Yong-qi
authors.initials: YQ
authors.lastname: Tian
authors.forename: Xiu-ping
authors.initials: XP
authors.lastname: Lin
authors.forename: Juan
authors.initials: J
authors.lastname: Liu
authors.forename: Kumaravel
authors.initials: K
authors.lastname: Kaliyaperumal
authors.forename: Wen
authors.initials: W
authors.lastname: Ai
authors.forename: Zhi-ran
authors.initials: ZR
authors.lastname: Ju
authors.forename: Bin
authors.initials: B
authors.lastname: Yang
authors.forename: Junfeng
authors.initials: J
authors.lastname: Wang
authors.forename: Xian-wen
authors.initials: XW
authors.lastname: Yang
authors.forename: Yonghong
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification; D001203:Ascomycota / Q000737:chemistry*; D019015:Geologic Sediments / Q000382:microbiology; D006575:Heterocyclic Compounds, 3-Ring / Q000737:chemistry* / Q000302:isolation & purification; D019156:Indian Ocean; D015394:Molecular Structure; D011753:Pyrones / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D006575:Heterocyclic Compounds, 3-Ring; D011753:Pyrones; C000598481:ascomycotin A; C013444:citromycetin
keywords: citromycetin analogue; deep sea sediment; fungi; spectroscopy