title: Use of a novel hemoadsorption device for cytokine removal as adjuvant therapy in a patient with septic shock with multi-organ dysfunction: A case study.
abstract: CytoSorb(®) (CytoSorbents Corporation, USA) is a novel sorbent hemoadsorption device for cytokine removal. The aim of this study was to examine the clinical use of CytoSorb(®) in the management of patient with septic shock. We used this device as an adjuvant to stabilize a young patient with multi-organ failure and severe sepsis with septic shock. A 36-year-old female patient was hospitalized with the complaints of malaise, general body ache, and breathing difficulty and had a medical history of diabetes mellitus type II, hypertension, obstructive sleep apnea, hypothyroidism and morbid obesity. She was diagnosed to have septic shock with multi-organ dysfunction (MODS) and a low perfusion state. CytoSorb(®) hemoadsorption column was used as an attempt at blood purification. Acute physiology and chronic health evaluation score, MODS score, and sequential organ failure assessment score were measured before and after the device application. CytoSorb application as an adjuvant therapy could be considered in septic shock.
authors.affiliation: Department of Critical Care, Sector-51, Gurgaon, Haryana, India.
authors.forename: Reshma
authors.initials: R
authors.lastname: Basu
authors.affiliation: Department of Artemis Health Institute, Sector-51, Gurgaon, Haryana, India.
authors.forename: Sunjay
authors.initials: S
authors.lastname: Pathak
authors.affiliation: Department of Artemis Health Institute, Sector-51, Gurgaon, Haryana, India.
authors.forename: Jyoti
authors.initials: J
authors.lastname: Goyal
authors.affiliation: Department of Artemis Health Institute, Sector-51, Gurgaon, Haryana, India.
authors.forename: Rajeev
authors.initials: R
authors.lastname: Chaudhry
authors.affiliation: Department of Artemis Health Institute, Sector-51, Gurgaon, Haryana, India.
authors.forename: Rati B
authors.initials: RB
authors.lastname: Goel
authors.affiliation: Department of Artemis Health Institute, Sector-51, Gurgaon, Haryana, India.
authors.forename: Anil
authors.initials: A
authors.lastname: Barwal
keywords: CytoSorb; hemoadsorption; septic shock; systemic inflammatory response syndrome