title: Review and updates of immunohistochemistry in selected salivary gland and head and neck tumors.
abstract: BACKGROUND
  Immunohistochemistry is a useful tool for diagnosing salivary gland and head and neck tumors.
  
  
  OBJECTIVE
  To review immunohistochemical markers, which can aid in the diagnosis of selected salivary gland and head and neck tumors.
  
  
  METHODS
  Literature review and authors' personal practice experience.
  
  
  CONCLUSIONS
  Salivary gland and head and neck tumors include a large diverse group of tumors with complex and overlapping histologic features. Immunohistochemistry plays an important role in resolving the differential diagnosis of some salivary gland and head and neck tumors and can provide information for the prognosis of certain tumors.
authors.affiliation: From the Department of Laboratory Medicine, Geisinger Medical Center, Danville, Pennsylvania (Drs Zhu and Schuerch);
authors.forename: Shaobo
authors.initials: S
authors.lastname: Zhu
authors.forename: Conrad
authors.initials: C
authors.lastname: Schuerch
authors.forename: Jennifer
authors.initials: J
authors.lastname: Hunt
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D003937:Diagnosis, Differential; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*; D011379:Prognosis; D015203:Reproducibility of Results; D012468:Salivary Gland Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D012680:Sensitivity and Specificity
chemical_list: D014408:Biomarkers, Tumor