title: Is there a role for PET/CT with esophagogastric junction adenocarcinoma?
abstract: The value of 18F-FDG PET/CT in the initial diagnosis and in the locoregional staging of esophagogastric junction adenocarcinoma is not fully established. However, 18F-FDG PET/CT is widely accepted as the best modality for identification of suspected metastases in staging of the disease. Results published in the literature suggest that 18F-FDG PET/CT may provide useful information for response assessment to neoadjuvancy and to differentiate responding and nonresponding tumors. We review the potential role of 18F-FDG PET/CT imaging in staging, restaging, and prognostic value after chemoradiation therapy in esophagogastric junction adenocarcinoma.
authors.affiliation: From the *Department of Nuclear Medicine, Hospital Clínic, Barcelona, Spain; †Department of Nuclear Medicine, Santa Maria della Misericordia Hospital, Rovigo, Italy; ‡Department of Medical Oncology, §Endoscopy Unit, and ∥Department of Radiology, Hospital Clínic, Barcelona, Spain; and ¶Department of Radiology, University of Southern California, Los Angeles, CA.
authors.forename: David
authors.initials: D
authors.lastname: Fuster
authors.forename: Maria
authors.initials: M
authors.lastname: Mayoral
authors.forename: Domenico
authors.initials: D
authors.lastname: Rubello
authors.forename: Estela
authors.initials: E
authors.lastname: Pineda
authors.forename: Gloria
authors.initials: G
authors.lastname: Fernández-Esparrach
authors.forename: Mario
authors.initials: M
authors.lastname: Pagès
authors.forename: Patrick M
authors.initials: PM
authors.lastname: Colletti
authors.forename: Francesca
authors.initials: F
authors.lastname: Pons
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging*; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging*; D004943:Esophagogastric Junction / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18