title: Massive intrathoracic lipoma in men1 syndrome.
abstract: BACKGROUND
  The multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant syndrome characterized by the onset of hyperparathyroidism, gastroenteropancreatic neuroendocrine tumors and pituitary lesions.
  
  
  METHODS
  This appears to be the first described case of a massive intrathoracic lipoma in MEN1. The patient was affected with primary hyperparathyroidism treated with a total parathyroidectomy followed by a distal pancreatectomy for insulinoma. At follow-up, the computed tomography showed a massive lesion on the left emithorax suggestive of a lipoma. At the onset of a mild dyspnea we decided to perform the surgical excision of the mass obtaining a complete relief of the symptoms.
  
  
  CONCLUSIONS
  This case is evidence of the importance of a strict follow-up of such patients.
  
  
  CONCLUSIONS
  Lipomas are the most frequent benign soft tissue tumors. They are usually sporadic but are sometimes related to hereditary syndromes. Intrathoracic localizations are rare and can arise mainly in the mediastinum, bronchus or lung. The diagnosis is often incidental; despite preoperative imaging will accurately show the features of the lesions, it is impossible obtain an accurate diagnosis-hence, the treatment of choice remains the surgical excision.
authors.affiliation: Digestive Surgery Unit, Department of Surgery and Translational Medicine, University of Florence Medical School, Careggi University Hospital, Florence, Italy. Electronic address: alexstur@yahoo.it.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Sturiale
authors.affiliation: Digestive Surgery Unit, Department of Surgery and Translational Medicine, University of Florence Medical School, Careggi University Hospital, Florence, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Giudici
authors.affiliation: Digestive Surgery Unit, Department of Surgery and Translational Medicine, University of Florence Medical School, Careggi University Hospital, Florence, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Alemanno
authors.affiliation: Digestive Surgery Unit, Department of Surgery and Translational Medicine, University of Florence Medical School, Careggi University Hospital, Florence, Italy.
authors.forename: Tiziana
authors.initials: T
authors.lastname: Cavalli
authors.affiliation: Digestive Surgery Unit, Department of Surgery and Translational Medicine, University of Florence Medical School, Careggi University Hospital, Florence, Italy.
authors.forename: Rami
authors.initials: R
authors.lastname: Addasi
authors.affiliation: Department of Pneumology, University of Florence Medical School, Careggi University Hospital, Florence, Italy.
authors.forename: Carmine
authors.initials: C
authors.lastname: Santomaggio
authors.affiliation: Department of Oncology, Medical Oncology 1, Careggi University Hospital, Florence, Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Meoni
authors.affiliation: Regional Centre for Hereditary Endocrine Tumors, Unit of Metabolic Bone Diseases, Department of Internal Medicine, University of Florence, Florence, Italy.
authors.forename: Maria Luisa
authors.initials: ML
authors.lastname: Brandi
authors.affiliation: Digestive Surgery Unit, Department of Surgery and Translational Medicine, University of Florence Medical School, Careggi University Hospital, Florence, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Tonelli
keywords: GEP-NET; Intrathoracic lipoma; MEN 1 syndrome; Surgery