title: [Glanzmann thrombasthenia and pregnancy--report of a case and literature review].
abstract: Glanzmann thrombasthenia (GT) is a rare autosomal recessive disorder which deficiency of the platelet glycoprotein IIb - III a. The disorder usually manifests as severe mucocutaneus bleeding in the chaildhood, menstrual patterns in pubertal--adolescent years, rarely life-threatening. Pregnancy and delivery in patients with TG are very rare and are associated with high risk for mother and fetus due to intra - and post-partum hemorrhage. We present a case 30, a patient with TG, emergency births by caesarean section, with intra- and postpartum haemorrhage managed through the use of recombinant factor VIIa, transfusion of packed red blood cells and platelets.
authors.forename: E
authors.initials: E
authors.lastname: Uchikova
authors.forename: B
authors.initials: B
authors.lastname: Pechlivanov
authors.forename: N
authors.initials: N
authors.lastname: Parahuleva
authors.forename: G
authors.initials: G
authors.lastname: Amaliev
mesh_terms: D000328:Adult; D002585:Cesarean Section; D017707:Erythrocyte Transfusion; D015942:Factor VIIa / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D017713:Platelet Transfusion; D006473:Postpartum Hemorrhage / Q000628:therapy*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000628:therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use; D013915:Thrombasthenia / Q000628:therapy*
chemical_list: D011994:Recombinant Proteins; C103587:recombinant FVIIa; D015942:Factor VIIa