title: Urinary tract infection in patients with chronic kidney disease.
abstract: OBJECTIVE
  Chronic kidney disease (CKD) has become a burden of health care globally. However, data on epidemiology, clinical features, and outcomes of urinary tract infection (UTI) in this population are scarce. This study aims to retrospectively review such data.
  
  
  METHODS
  A retrospective cohort study was conducted from 1 January 2005 to 31 December 2011 in patients with CKD requiring hospitalization. Patients who had upper and lower UTIs were compared for demography and clinical data. Logistic regressior was used to assess which variables were associated with upper UTI.
  
  
  RESULTS
  A total of 276 bacteriuria patients were admitted to our ward with upper and lower UTIs. The average ages of the upper and lower UTI patients were 59.21 +/- 16.54 and 71.18 +/- 14.77 years, respectively. The results of logistic regression analysis showed that age (OR 0.946, P < 0.001), female sex (OR 4.695, P < 0.001), and renal stones (OR 8.232, P < 0.001) were independently associated with upper UTI.
  
  
  CONCLUSIONS
  This study shows that patients with CKD and UTIs were elderly, and that females were prone to have more bacteriuria and upper UTIs than males. In addition, patients who had renal stones were more prone to have upper UTI than other bacteriuria patients Aggressive treatment of renal stones should be considered in these patients.
authors.affiliation: Department of Internal Medicine, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Taiwan.
authors.forename: Chih-yen
authors.initials: CY
authors.lastname: Hsiao
authors.forename: Hsing-lin
authors.initials: HL
authors.lastname: Lin
authors.forename: Yen-ko
authors.initials: YK
authors.lastname: Lin
authors.forename: Chao-wen
authors.initials: CW
authors.lastname: Chen
authors.forename: Yuan-chia
authors.initials: YC
authors.lastname: Cheng
authors.forename: Wei-che
authors.initials: WC
authors.lastname: Lee
authors.forename: Tzu-chin
authors.initials: TC
authors.lastname: Wu
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000150:complications; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D051436:Renal Insufficiency, Chronic / Q000150:complications*; D012189:Retrospective Studies; D014552:Urinary Tract Infections / Q000209:etiology*