title: The plethora of PMCA isoforms: Alternative splicing and differential expression.
abstract: In this review the four different genes of the mammalian plasma membrane calcium ATPase (PMCA) and their spliced isoforms are discussed with respect to their tissue distribution, their differences during development and their importance for regulating Ca²⁺ homeostasis under different conditions. This article is part of a Special Issue entitled: 13th European Symposium on Calcium.
authors.affiliation: NMR-Based Structural Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany. Electronic address: jkrebs@nmr.mpibpc.mpg.de.
authors.forename: Joachim
authors.initials: J
authors.lastname: Krebs
mesh_terms: D017398:Alternative Splicing / Q000502:physiology*; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D015971:Gene Expression Regulation, Enzymologic / Q000502:physiology*; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D007527:Isoenzymes / Q000096:biosynthesis / Q000235:genetics; D053499:Plasma Membrane Calcium-Transporting ATPases / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D007527:Isoenzymes; D053499:Plasma Membrane Calcium-Transporting ATPases; D002118:Calcium
keywords: Alternative splicing; PMCA; Plasma membrane calcium ATPase; Spliced isoform