title: Roles of non-coding RNA in pancreatic islet development and functioning.
abstract: Non-coding RNA is a kind of non-coding protein RNA which is widely present in most of the organisms. Non-coding RNA plays key roles in the embryonic development,cell fate determination,and growth control in the living organisms. MicroRNA and long non-coding RNA involve in differentiation of endocrine cell,insulin gene expression and secretion,and insulin resistance,which are closely associated with diabetes.
authors.affiliation: Laboratory Center for Basic Medical Sciences,Nanjing Medical University,Nanjing 210029,China.
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Jin
authors.affiliation: Laboratory Center for Basic Medical Sciences,Nanjing Medical University,Nanjing 210029,China.
authors.forename: Jian-Feng
authors.initials: JF
authors.lastname: Wang
authors.affiliation: Laboratory Center for Basic Medical Sciences,Nanjing Medical University,Nanjing 210029,China; Department of Biochemistry and Molecular Biology, Nanjing Medical University,Nanjing 210029,China.
authors.forename: Xue-Jun
authors.initials: XJ
authors.lastname: Wang
authors.affiliation: Department of Biochemistry and Molecular Biology, Nanjing Medical University,Nanjing 210029,China.
authors.forename: Li
authors.initials: L
authors.lastname: Yuan
mesh_terms: D002454:Cell Differentiation; D003920:Diabetes Mellitus; D015870:Gene Expression / Q000502:physiology; D020869:Gene Expression Profiling; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D007328:Insulin; D050417:Insulin-Secreting Cells; D007515:Islets of Langerhans / Q000254:growth & development* / Q000378:metabolism; D035683:MicroRNAs; D022661:RNA, Untranslated / Q000378:metabolism*
chemical_list: D007328:Insulin; D035683:MicroRNAs; D022661:RNA, Untranslated