title: [Validation of standardized uptake values for ¹⁸F-FDG in normal organs: comparison of whole-body PET/CT and PET/MRI].
abstract: OBJECTIVE
  To validate whether PET/MR could provide a semi-quantitative measurement (SUV(max)) comparable to that produced by PET/CT in normal organs.
  
  
  METHODS
  277 subjects underwent an ordinary ¹⁸F-FDG PET/CT followed by a PET/MR scan with a 25-45 min interval. Region of interest (ROIs) were drawn in 4 reference normal organs/tissues in both MRAC-PET and CTAC-PET images and the liver and erector spinae in the dual-time point PET/CT images.
  
  
  RESULTS
  259 malignant and 21 benign lesions, pathologically confirmed, were detected in the 220 subjects. SUV(max) derived from PET/CT (SUV(max)-CT) and PET/MR (SUV(max)-MRI) was highly correlated over the reference organ ROIs (r = 0.62-0.73), except lung (r = 0.44). The SUV(max)-MRI was significantly lower than the respective SUV(max)-CT in all 4 organs and after delay-correction in liver and muscle.
  
  
  CONCLUSIONS
  The results indicate that PET/MR can provide reliable measurement in physiological organs.
authors.affiliation: Department of Nuclear Medicine, the General Hospital of PLA, Beijing 100853, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Fu
authors.forename: Jiajin
authors.initials: J
authors.lastname: Liu
authors.forename: Dayi
authors.initials: D
authors.lastname: Yin
authors.forename: Jinming
authors.initials: J
authors.lastname: Zhang
authors.forename: Yingmao
authors.initials: Y
authors.lastname: Chen
authors.forename: Ningyu
authors.initials: N
authors.lastname: An
authors.forename: Baixuan
authors.initials: B
authors.lastname: Xu
authors.affiliation: Email: tianjh@vip.sina.com.
authors.forename: Jiahe
authors.initials: J
authors.lastname: Tian
mesh_terms: D019788:Fluorodeoxyglucose F18; D006801:Humans; D008099:Liver; D008168:Lung; D008279:Magnetic Resonance Imaging; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18