title: Acute pancreatitis associated with herpes zoster: case report and literature review.
abstract: Varicella-zoster virus (VZV) is a type of herpes virus known to cause varicella, mainly in young children, and herpes zoster in adults. Although generally non-lethal, VZV infection can be associated with serious complications, particularly in adults. Acute pancreatitis caused by VZV infection is a rare event, with reports primarily concerning immunocompromised individuals. Here we report a 44-year-old immunocompetent female who developed acute pancreatitis associated with VZV infection. The patient presented with vomiting and persistent pain in the upper quadrant less than one week after diagnosis and treatment for a herpes zoster-related rash with stabbing pain on the abdomen and dorsal right trunk side. A diagnosis of acute pancreatitis was confirmed based on abdominal pain, elevated levels of urine and serum amylase, and findings of peri-pancreatic exudation and effusions by computed tomography and magnetic resonance cholangiopancreatography. This case highlights that, though rare, acute pancreatitis should be considered in VZV patients who complain of abdominal pain, especially in the epigastric area. Early detection and proper treatment are needed to prevent the condition from deteriorating further and to minimize mortality.
authors.affiliation: Zhen Wang, Cancer Institute, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Zhen Wang, Cancer Institute, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Ye
authors.affiliation: Zhen Wang, Cancer Institute, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China.
authors.forename: Yue-Hua
authors.initials: YH
authors.lastname: Han
mesh_terms: D015746:Abdominal Pain / Q000821:virology; D000208:Acute Disease; D000328:Adult; D049448:Cholangiopancreatography, Magnetic Resonance; D042241:Early Diagnosis; D005260:Female; D006562:Herpes Zoster / Q000150:complications / Q000175:diagnosis / Q000276:immunology / Q000628:therapy / Q000821:virology*; D014645:Herpesvirus 3, Human / Q000302:isolation & purification*; D006801:Humans; D007121:Immunocompetence; D010195:Pancreatitis / Q000175:diagnosis / Q000276:immunology / Q000628:therapy / Q000821:virology*; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Acute pancreatitis; Herpes zoster; Immunocompetent adult; Varicella-zoster virus