title: Future prospects: assessment of intraoperative optical coherence tomography in ab interno glaucoma surgery.
abstract: OBJECTIVE
  Ab interno glaucoma surgery, such as trabecular aspiration or ab interno trabeculotomy, has been introduced as an alternative, non-filtering procedure to lower intraocular pressure in glaucoma patients. The purpose of the present study was to assess the feasibility of intraoperative spectral domain optical coherence tomography (iOCT) for improving ab interno glaucoma surgery.
  
  
  METHODS
  Intraoperative optical coherence tomography was performed to visualize the anterior chamber angle, the aspiration canula during trabecular aspiration, and the trabectome device during ab interno trabeculotomy. A commercially available 840-nm iOCT was used in a clinical setting, a 1310-nm spectral-domain OCT in an experimental setting.
  
  
  RESULTS
  In the clinical setting using the 840-nm iOCT, visualization of the aspiration canula and the trabectome device was possible, however, with rather limited visibility of the chamber angle and the trabecular meshwork. In the experimental setting, the 1310-nm OCT enabled excellent visualization of the chamber angle and detailed evaluation of the instrument-trabecular meshwork relation.
  
  
  CONCLUSIONS
  Intraoperative use of optical coherence tomography may be helpful for ab interno glaucoma surgery. Adjustments of the commercially available iOCT, including longer wavelengths and oblique scanning options, are necessary for the clinical use.
authors.affiliation: a Department of Ophthalmology , University of Cologne , Cologne , Germany and.
authors.forename: Ludwig M
authors.initials: LM
authors.lastname: Heindl
authors.affiliation: a Department of Ophthalmology , University of Cologne , Cologne , Germany and.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Siebelmann
authors.affiliation: a Department of Ophthalmology , University of Cologne , Cologne , Germany and.
authors.forename: Thomas
authors.initials: T
authors.lastname: Dietlein
authors.affiliation: b Institute of Biomedical Optics, University of Luebeck , Luebeck , Germany , and.
authors.forename: Gereon
authors.initials: G
authors.lastname: Hüttmann
authors.affiliation: c OptoMedical Technologies GmbH , Luebeck , Germany.
authors.forename: Eva
authors.initials: E
authors.lastname: Lankenau
authors.affiliation: a Department of Ophthalmology , University of Cologne , Cologne , Germany and.
authors.forename: Claus
authors.initials: C
authors.lastname: Cursiefen
authors.affiliation: a Department of Ophthalmology , University of Cologne , Cologne , Germany and.
authors.forename: Philipp
authors.initials: P
authors.lastname: Steven
mesh_terms: D000368:Aged; D017889:Exfoliation Syndrome / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D018918:Phacoemulsification; D025321:Surgery, Computer-Assisted; D041623:Tomography, Optical Coherence / Q000379:methods*; D014130:Trabeculectomy / Q000379:methods*
keywords: Ab interno glaucoma surgery; iOCT; intraoperative imaging; intraoperative optical coherence tomography