title: Design and synthesis of novel bis-annulated caged polycycles via ring-closing metathesis: pushpakenediol.
abstract: Intricate caged molecular frameworks are assembled by an atom economical process via a Diels-Alder (DA) reaction, a Claisen rearrangement, a ring-closing metathesis (RCM) and an alkenyl Grignard addition. The introduction of olefinic moieties in the pentacycloundecane (PCUD) framework at appropriate positions followed by RCM led to the formation of novel heptacyclic cage systems.
authors.affiliation: Department of Chemistry, Indian Institute of Technology-Bombay, Powai, India.
authors.forename: Sambasivarao
authors.initials: S
authors.lastname: Kotha
authors.affiliation: Department of Chemistry, Indian Institute of Technology-Bombay, Powai, India.
authors.forename: Mirtunjay Kumar
authors.initials: MK
authors.lastname: Dipak
keywords: Diels–Alder cycloaddition; Grignard addition; pentacycloundecane (PCUD); ring-closing metathesis