title: Clinical characteristics of patients with abnormal ocular/cervical vestibular evoked myogenic potentials in the presence of normal caloric responses.
abstract: OBJECTIVE
  To investigate the clinical features and vestibular symptoms of patients with abnormal ocular vestibular evoked myogenic potentials (oVEMPs) and/or cervical VEMPs (cVEMPs) in the presence of normal caloric responses.
  
  
  METHODS
  Retrospective chart review.
  
  
  METHODS
  Tertiary referral center.
  
  
  METHODS
  One thousand five hundred twenty-one consecutive patients with balance problems who underwent the caloric, cVEMP, and oVEMP tests were included, and patients who showed abnormal oVEMPs and/or cVEMPs in the presence of normal caloric responses were selected. Clinical characteristics, diagnoses, and vestibular symptoms of the patients were analyzed.
  
  
  RESULTS
  Of the 1521 patients, 227 (15%) were found to have abnormal oVEMPs and/or cVEMP responses with normal caloric responses. Benign paroxysmal positional vertigo (BBPV), Meniere's disease, and vestibular migraine were the common diagnoses of these patients. Eighty-one patients (36%) could not be diagnosed with a recognizable disease. Multiple episodes of spinning vertigo with a duration of seconds to hours were their most common vestibular symptoms.
  
  
  CONCLUSIONS
  BPPV, Meniere's disease, and vestibular migraine are the most frequent diagnoses showing abnormal oVEMP and/or cVEMPs without canal paresis. Apart from these clinical entities, a portion of undiagnosed patients with multiple episodes of vertigo might have a disease that involves the otolith organs only.
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan iwashin-tky@umin.ac.jp.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Iwasaki
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Chisato
authors.initials: C
authors.lastname: Fujimoto
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Kinoshita
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Teru
authors.initials: T
authors.lastname: Kamogashira
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Naoya
authors.initials: N
authors.lastname: Egami
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Yamasoba
mesh_terms: D065635:Benign Paroxysmal Positional Vertigo / Q000175:diagnosis* / Q000503:physiopathology; D002150:Caloric Tests / Q000379:methods*; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis* / Q000503:physiopathology; D008875:Middle Aged; D015203:Reproducibility of Results; D012189:Retrospective Studies; D058585:Vestibular Evoked Myogenic Potentials / Q000502:physiology*
keywords: otolith; saccule; utricle; vestibular; vestibular evoked myogenic potential