title: [Associations of blood pressure, glucose or lipids with stroke in different age or gender].
abstract: OBJECTIVE
  To investigate the relationship between blood pressure, blood glucose or blood lipids and patients with cerebral infarction (CI) or intracerebral hemorrhage (ICH) in different age or gender.
  
  
  METHODS
  Th e case-control study consecutively recruited patients with fi rst-ever-in-a-lifetime CI (n=358) and ICH (n=230) and community-acquired pneumonia (n=165) as controls between January 2010 and December 2013 at the Second Xiangya Hospital of Central South University. The patients with CI or ICH were divided into the young group, the middle-aged group and the older group, and the risk factors were compared between the 3 groups. The patients with CI or ICH were respectively further divided into the male group and the female group. The blood pressure, glucose and lipids were measured.
  
  
  RESULTS
  Data from logistic regression models showed that CI was closely associated with high blood pressure, hypertension, diabetes mellitus (DM) or fasting plasma glucose (FPG) (P< 0.05), and ICH was closely related to high blood pressure, hypertension, low density lipoproteincholesterol (LDL-C), FPG, serum creatinine (SCr) or alcohol drinking (P< 0.05); hypertension was the main risk factor for stroke. The odds ratios for the young, the middle-aged and older group were 10.43, 4.74 and 7.39 respectively (P< 0.05). Systolic blood pressure (OR=28.74) was the important risk factor for the young stroke, and the OR is 2.81 for the middle-aged stroke. Diastolic blood pressure (OR=2.96) and DM (OR=6.25) were the risk factor for the middle-aged stroke. LDL-C (OR=2.87) was a risk factor for the older stroke; the mean levels of diastolic blood pressure in males were significantly increased compared with that in females with CI, while the mean levels of TC, HDL-C or LDL-C in females were significantly higher than that in males with ICH (P< 0.05).
  
  
  CONCLUSIONS
  Hypertension, systolic blood pressure in particular, is the most common risk factor for young stroke patients. DM and hypertension are the risk factors for the middle-aged patients, while hypertension, DM, LDL-C and alcohol consuming are the risk factors for the aged patients.
authors.affiliation: Department of Emergency, Second Xiangya Hospital, Central South University, Changsha 410011,China zhuaiqun1974@126.com.
authors.forename: Aiqun
authors.initials: A
authors.lastname: Zhu
authors.forename: Jingping
authors.initials: J
authors.lastname: Zhang
authors.forename: Ting
authors.initials: T
authors.lastname: Zou
authors.forename: Guangzhong
authors.initials: G
authors.lastname: Xiong
mesh_terms: D000367:Age Factors; D001786:Blood Glucose; D001794:Blood Pressure; D016022:Case-Control Studies; D002543:Cerebral Hemorrhage; D002544:Cerebral Infarction; D003920:Diabetes Mellitus; D005260:Female; D006801:Humans; D006973:Hypertension; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012737:Sex Factors; D020521:Stroke / Q000503:physiopathology*
chemical_list: D001786:Blood Glucose; D008055:Lipids