title: Measurement of cerebral blood volume dynamics during volitional swallowing using functional near-infrared spectroscopy: an exploratory study.
abstract: The aim of this study was to examine cerebral blood volume dynamics during volitional swallowing using multi-channel functional near-infrared spectroscopy (fNIRS) to understand the basic cortical activation patterns. Fifteen volunteers (age, 26.5±1.3 years, mean±SD) performed volitional swallowing of a 5-ml bolus of water as a task. A 52-channel fNIRS system was used for measuring oxy-Hb levels. We determined the oxy-Hb concentration changes in each channel by calculating the differences between rest and task oxy-Hb levels. Differences in rest and task data were assessed using a paired-t test (p<0.05). A significant increase in oxy-Hb was found in 21 channels. The cortical regions that exhibited increased oxy-Hb concentration included the bilateral precentral gyrus, postcentral gyrus, inferior frontal gyrus, superior temporal gyrus, middle temporal gyrus, and supramarginal gyrus. These data provide a description of cortical activation patterns during volitional swallowing using fNIRS, which will be useful for the evaluation of dysphasia and the effects of the rehabilitation [Corrected].
authors.affiliation: Department of Endodontics, School of Dentistry, Aichi Gakuin University, Aichi, Japan. Electronic address: kyon@dpc.agu.ac.jp.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Inamoto
authors.affiliation: Department of Fixed Prosthodontics, School of Dentistry, Aichi Gakuin University, Aichi, Japan.
authors.forename: Shigemitsu
authors.initials: S
authors.lastname: Sakuma
authors.affiliation: Department of Oral and Maxillofacial Radiology, School of Dentistry, Aichi Gakuin University, Aichi, Japan.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Ariji
authors.affiliation: Department of Endodontics, School of Dentistry, Aichi Gakuin University, Aichi, Japan.
authors.forename: Naoya
authors.initials: N
authors.lastname: Higuchi
authors.affiliation: Department of Oral and Maxillofacial Radiology, School of Dentistry, Aichi Gakuin University, Aichi, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Izumi
authors.affiliation: Department of Endodontics, School of Dentistry, Aichi Gakuin University, Aichi, Japan.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nakata
mesh_terms: D000328:Adult; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000098:blood supply / Q000502:physiology*; D002560:Cerebrovascular Circulation; D003679:Deglutition; D005260:Female; D006801:Humans; D008297:Male; D010108:Oxyhemoglobins / Q000032:analysis; D011187:Posture; D019265:Spectroscopy, Near-Infrared
chemical_list: D010108:Oxyhemoglobins
keywords: Cerebral blood volume dynamics; Cortical activation; Functional near-infrared spectroscopy; Volitional swallowing