title: [The use of structural proximal tibial allografts coated with human albumin in treating extensive periprosthetic knee-joint bone deficiency and averting late complications. Case report].
abstract: The authors report the history of a 74-year-old patient who underwent surgical treatment for segmental knee-joint periprosthetic bone loss using structural proximal tibial allografts coated with serum albumin. Successful treatment of late complications which occurred in the postoperative period is also described. The authors emphasize that bone replacement with allografts is a physiological process that enables the stable positioning of the implant and the reconstruction of the soft tissues, the replacement of extensive bone loss, and also it is a less expensive operation. It has been already confirmed that treatment of lyophilised allografts with albumin improves the ability of bone marrow-derived mesenchymal stem cells to adhere and proliferate the surface of the allografts, penetrate the pores and reach deeper layers of the graft. Earlier studies have shown osteoblast activity on the surface and interior of the graft.
authors.affiliation: Bács-Kiskun Megyei Kórház Ortopédiai Osztály Kecskemét Nyíri út 38. 6000.
authors.forename: Tamás
authors.initials: T
authors.lastname: Klára
authors.affiliation: Petz Aladár Megyei Oktató Kórház Nyugat-magyarországi Regionális Szövetbank Osztály Győr.
authors.forename: Lajos
authors.initials: L
authors.lastname: Csönge
authors.affiliation: Bács-Kiskun Megyei Kórház Ortopédiai Osztály Kecskemét Nyíri út 38. 6000.
authors.forename: Gábor
authors.initials: G
authors.lastname: Janositz
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Traumatológiai Tanszék Budapest Uzsoki Kórház Ortopédiai-Traumatológiai Osztály Budapest.
authors.forename: Károly
authors.initials: K
authors.lastname: Pap
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar Ortopédiai Klinika Budapest.
authors.forename: Zsombor
authors.initials: Z
authors.lastname: Lacza
mesh_terms: D000368:Aged; D000418:Albumins / Q000627:therapeutic use*; D064591:Allografts; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D016025:Bone Transplantation / Q000379:methods*; D001842:Bone and Bones / Q000473:pathology*; D005260:Female; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control; D013977:Tibia / Q000601:surgery*; D014184:Transplantation, Homologous; D016896:Treatment Outcome
chemical_list: D000418:Albumins
keywords: albumin coated allograft; albuminnal bevont allograft; allograft-prosthesis composite; fagyasztva szárított allograft; freeze-dried allograft; protézis-allograft kompozit; supply of complications; szövődmény ellátása; total knee prosthesis revision; térdprotézis-revízió