title: Evaluation of efficacy of regional and local anesthesia techniques in arteriovenous fistula criation for dialysis.
abstract: Both, regional and local anesthesia are used for dialysis arterio-venous fistula (AVF) formation in end-stage renal disease patients. There are no prospective, randomized clinical trials comparing effectiveness of these types of anesthesia in these patients. It was a prospective, randomized study. 103 patients with ESRD underwent dialysis AVF operations on upper limb. The patients have been randomly divided in two groups. Group I: 49 patients in whom the operations have been done under the local anesthesia; and Group II: 54 patients in whom the operation has been performed under the vertical infraclavicular block. Radio-Cefalic, Brachio-Cefalic and Brachio-Basilic(I stage transposition) fistulas have been created in all patients.Influence of the type of anesthesia on intra- and postoperative pain has been evaluated and compared between the groups. The mean follow-up was 359.5 days in Group I and 340.5 days in Group II (p-NS).The mean patients age was 59.7±13.1 years and 60.1±14 years in local and regional anesthesia groups, respectively (p=NS). For the whole group, significantly less number of patients with regional anesthesia required additional perioperative analgesics as compared with the local anesthesia group (p=0.0363). Time to postoperative pain initiation was significantly higher in Group II (2.3 hours) as compared with the Group I (1.7 hours, p=0.0477). The need for postoperative pain killers was significantly less in regional as compared with the local anesthesia (p=0.0318). Duration of operation was significantly less in regional (67.5 min.) as compared with local anesthesia (134.7 min. p=0.0007) group. This difference has been detected in Brachio-Cefalic and Brachio-Basilic fistulas (p=0.0257 and 0.001, respectively) but not in Radio-Cefalic one. No anesthesia related complications have been detected. Insufficiency of regional anesthesia has been identified in 3 cases (5.5%).In 5 patients from regional anesthesia group (9.4%) as a result of vasodilation have made more simplified operation. Regional anesthesia provides significantly betterperiperativeanalgesiaas compared with the local anesthesia in AVF operations. It can change the tactic of surgery, significantly decreases the operation time and should be a method of choice for some forms AVF operations.
authors.affiliation: Martin D. Abeloff Laboratory Cancer Research Center; Al. Tsulukidze National Center of Urology, Tbilisi, Georgia.
authors.forename: V
authors.initials: V
authors.lastname: Shoshiashvili
authors.affiliation: Martin D. Abeloff Laboratory Cancer Research Center; Al. Tsulukidze National Center of Urology, Tbilisi, Georgia.
authors.forename: A
authors.initials: A
authors.lastname: Tataradze
authors.affiliation: Martin D. Abeloff Laboratory Cancer Research Center;Al. Tsulukidze National Center of Urology, Tbilisi, Georgia.
authors.forename: L
authors.initials: L
authors.lastname: Beglarishvili
authors.affiliation: Martin D. Abeloff Laboratory Cancer Research Center; Al. Tsulukidze National Center of Urology, Tbilisi, Georgia.
authors.forename: L
authors.initials: L
authors.lastname: Managadze
authors.affiliation: Martin D. Abeloff Laboratory Cancer Research Center; Al. Tsulukidze National Center of Urology, Tbilisi, Georgia.
authors.forename: A
authors.initials: A
authors.lastname: Chkhotua
mesh_terms: D000368:Aged; D000765:Anesthesia, Conduction / Q000379:methods*; D000772:Anesthesia, Local / Q000379:methods*; D001164:Arteriovenous Fistula / Q000628:therapy*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000503:physiopathology / Q000628:therapy*