title: Signet-ring cell carcinoma arising from a fundic gland polyp in the stomach.
abstract: Fundic gland polyps (FGPs) are currently the most common type of gastric polyps and are usually benign. However, although rare, gastric adenocarcinoma of FGP has been recently proposed as a new variant of gastric adenocarcinoma. Here we report the first case of a 49-year-old woman with focal signet ring cell carcinoma that arose from an FGP of the stomach. The tumor was completely excised by endoscopic snare polypectomy. FGPs should therefore be evaluated for malignant changes although they occur rarely, if the FGP has an erosive or irregular surface.
authors.affiliation: Yong Seol Jeong, Sung Eun Kim, Jae Yong Seo, Hyun Lim, Ji Won Park, Ho Suk Kang, Sung Hoon Moon, Jong Hyuk Kim, Choong Kee Park, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, Anyang 431-796, South Korea.
authors.forename: Yong Seol
authors.initials: YS
authors.lastname: Jeong
authors.affiliation: Yong Seol Jeong, Sung Eun Kim, Jae Yong Seo, Hyun Lim, Ji Won Park, Ho Suk Kang, Sung Hoon Moon, Jong Hyuk Kim, Choong Kee Park, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, Anyang 431-796, South Korea.
authors.forename: Sung Eun
authors.initials: SE
authors.lastname: Kim
authors.affiliation: Yong Seol Jeong, Sung Eun Kim, Jae Yong Seo, Hyun Lim, Ji Won Park, Ho Suk Kang, Sung Hoon Moon, Jong Hyuk Kim, Choong Kee Park, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, Anyang 431-796, South Korea.
authors.forename: Mi-Jung
authors.initials: MJ
authors.lastname: Kwon
authors.affiliation: Yong Seol Jeong, Sung Eun Kim, Jae Yong Seo, Hyun Lim, Ji Won Park, Ho Suk Kang, Sung Hoon Moon, Jong Hyuk Kim, Choong Kee Park, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, Anyang 431-796, South Korea.
authors.forename: Jae Yong
authors.initials: JY
authors.lastname: Seo
authors.affiliation: Yong Seol Jeong, Sung Eun Kim, Jae Yong Seo, Hyun Lim, Ji Won Park, Ho Suk Kang, Sung Hoon Moon, Jong Hyuk Kim, Choong Kee Park, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, Anyang 431-796, South Korea.
authors.forename: Hyun
authors.initials: H
authors.lastname: Lim
authors.affiliation: Yong Seol Jeong, Sung Eun Kim, Jae Yong Seo, Hyun Lim, Ji Won Park, Ho Suk Kang, Sung Hoon Moon, Jong Hyuk Kim, Choong Kee Park, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, Anyang 431-796, South Korea.
authors.forename: Ji Won
authors.initials: JW
authors.lastname: Park
authors.affiliation: Yong Seol Jeong, Sung Eun Kim, Jae Yong Seo, Hyun Lim, Ji Won Park, Ho Suk Kang, Sung Hoon Moon, Jong Hyuk Kim, Choong Kee Park, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, Anyang 431-796, South Korea.
authors.forename: Ho Suk
authors.initials: HS
authors.lastname: Kang
authors.affiliation: Yong Seol Jeong, Sung Eun Kim, Jae Yong Seo, Hyun Lim, Ji Won Park, Ho Suk Kang, Sung Hoon Moon, Jong Hyuk Kim, Choong Kee Park, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, Anyang 431-796, South Korea.
authors.forename: Sung Hoon
authors.initials: SH
authors.lastname: Moon
authors.affiliation: Yong Seol Jeong, Sung Eun Kim, Jae Yong Seo, Hyun Lim, Ji Won Park, Ho Suk Kang, Sung Hoon Moon, Jong Hyuk Kim, Choong Kee Park, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, Anyang 431-796, South Korea.
authors.forename: Jong Hyuk
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Yong Seol Jeong, Sung Eun Kim, Jae Yong Seo, Hyun Lim, Ji Won Park, Ho Suk Kang, Sung Hoon Moon, Jong Hyuk Kim, Choong Kee Park, Department of Internal Medicine, University of Hallym College of Medicine, Hallym University Sacred Heart Hospital, Anyang 431-796, South Korea.
authors.forename: Choong Kee
authors.initials: CK
authors.lastname: Park
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D018279:Carcinoma, Signet Ring Cell / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D005260:Female; D005743:Gastrectomy / Q000379:methods; D005748:Gastric Fundus / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D005773:Gastroscopy / Q000379:methods; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D011127:Polyps / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D013272:Stomach Diseases / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D013274:Stomach Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor
keywords: Fundic gland polyp; Signet ring cell