title: Impact of antenatal depression on perinatal outcomes and postpartum depression in Korean women.
abstract: BACKGROUND
  Maternal prenatal mental health has been shown to be associated with adverse consequences for the mother and the child. However, studies considering the effect of prenatal depressive symptoms are lacking. The aim of this study was to examine the influence of antenatal depressive symptoms on obstetric outcomes and to determine associations between antenatal and postpartum depressions.
  
  
  METHODS
  This was a prospective cohort study. The Edinburgh postnatal depression scale (EPDS) questionnaire was completed by pregnant women receiving obstetrical care at Seoul St. Mary's hospital in the third trimester of gestation. The electronic medical records were reviewed after delivery and perinatal outcomes were evaluated. The association between antenatal and postpartum depression was analyzed using the EPDS questionnaire, which was completed by the same women within 2 months of delivery.
  
  
  RESULTS
  Of the 467 participants, 26.34% (n = 123) had antenatal depressive symptoms, with EPDS scores of ≥10. There were no significant perinatal outcomes associated with antenatal depressive symptoms. During the postpartum period, 192 of the women in the initial study cohort were given the EPDS again as a follow-up. Of the 192 participants, 56 (29.17%) scored >10. Spearman correlation coefficient between the antenatal and postpartum EPDS scores was 0.604, which was statistically significant (P < 0.001).
  
  
  CONCLUSIONS
  Antenatal depression does not lead to unfavorable perinatal outcomes. However, screening for antenatal depression may be helpful to identify women at risk of postpartum depression.
authors.affiliation: Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
authors.forename: Sae Kyung
authors.initials: SK
authors.lastname: Choi
authors.affiliation: Department of Biostatistics, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
authors.forename: Yong Gyu
authors.initials: YG
authors.lastname: Park
authors.affiliation: Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
authors.forename: In Yang
authors.initials: IY
authors.lastname: Park
authors.affiliation: Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
authors.forename: Hyun Sun
authors.initials: HS
authors.lastname: Ko
authors.affiliation: Department of Obstetrics and Gynecology, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
authors.forename: Jong Chul
authors.initials: JC
authors.lastname: Shin
keywords: Depression; postpartum; pregnancy; pregnancy outcome; prenatal care