title: A case of focal nodular hyperplasia with growth progression during pregnancy.
abstract: Focal nodular hyperplasia (FNH) is the second most common benign solid tumor of the liver and is usually found in young females. In FNH, spontaneous bleeding or rupture rarely occurs and malignant transformation is unlikely. The etiology of FNH is unclear, but because of female predominance and young age at onset, it seems that female hormone has an important role for the development of FNH. Although the development and the complications of hepatocellular adenomas have been related to the use of oral contraceptives and pregnancy, the influence of oral contraceptives and pregnancy on the growth and complications of FNH is controversial. Most FNH are stable in size and rarely complicated during pregnancy. We describe here a case of FNH with growth progression during pregnancy in a 27-year-old female. Her course of pregnancy and delivery was uneventful. Two months after delivery, the size of FNH was decreased.
authors.affiliation: Department of Gastroenterology, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Min Ji
authors.initials: MJ
authors.lastname: Kim
authors.affiliation: Department of Gastroenterology, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Sang Young
authors.initials: SY
authors.lastname: Han
authors.affiliation: Department of Gastroenterology, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Yang Hyun
authors.initials: YH
authors.lastname: Baek
authors.affiliation: Department of Gastroenterology, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Sung Wook
authors.initials: SW
authors.lastname: Lee
authors.affiliation: Department of Radiology, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Hee Jin
authors.initials: HJ
authors.lastname: Kwon
mesh_terms: D000328:Adult; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D011247:Pregnancy; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins
keywords: Focal nodular hyperplasia; Hepatic adenoma; Pregnancy