title: A case of multiple myeloma with metachronous chronic myeloid leukemia treated successfully with bortezomib, dexamethasone, and dasatinib.
abstract: The coexistence of multiple myeloma and chronic myeloid leukemia in a single patient is a very rare event that has been reported very infrequently in the literature. We report a case of a patient who developed chronic myeloid leukemia four years after his diagnosis with multiple myeloma. Historically, no link between the two malignancies has been identified. This synchronous existence complicates the treatment plan for these patients, and there is a lack of evidence on the best therapeutic approach. Our patient was successfully treated with a combination of bortezomib, dexamethasone, and dasatinib, which he tolerated well for eleven months until he eventually succumbed to cardiac complications and pulmonary hypertension leading to his death.
authors.affiliation: Department of Internal Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.
authors.forename: Samer
authors.identifier: 0000-0002-8440-5587
authors.initials: S
authors.lastname: Alsidawi
authors.affiliation: Division of Hematology-Oncology, Department of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.
authors.forename: Abhimanyu
authors.identifier: 0000-0001-6524-0476
authors.initials: A
authors.lastname: Ghose
authors.affiliation: Department of Pathology, University of Cincinnati, Cincinnati, OH 45267, USA.
authors.forename: Julianne
authors.identifier: 0000-0003-1005-622X
authors.initials: J
authors.lastname: Qualtieri
authors.affiliation: Division of Hematology-Oncology, Department of Medicine, University of Cincinnati, Cincinnati, OH 45267, USA.
authors.forename: Neetu
authors.initials: N
authors.lastname: Radhakrishnan