title: [Corticotherapy in aggressive chronic hepatitis (ACH)].
abstract: 48 patients with the diagnosis of ACH, admitted in the interval 1972-1981 and subjuected to corticotherapy were investigated by hepatic puncture biopsy with Vim-Silverman needls. The dose of prednison was of 15-20 mg daily for 2-4 years, with a mean 20 months. Corticotherapy was efficient in 73% of the cases, stabilization of the clinical and hepatic functional pictures being obtained. In 17% of the cases the hepatic process persited unmodified and in 10% ACH evolved towards cirrhosis.
authors.affiliation: Institutul de medicină şi farmacie Iaşi.
authors.forename: D
authors.initials: D
authors.lastname: Dobre
authors.forename: G
authors.initials: G
authors.lastname: Datcu
authors.forename: S
authors.initials: S
authors.lastname: Botezatu
authors.forename: I
authors.initials: I
authors.lastname: Bostaca
authors.forename: O
authors.initials: O
authors.lastname: Cioară
authors.forename: M
authors.initials: M
authors.lastname: Caţăr
authors.forename: F
authors.initials: F
authors.lastname: Curic
mesh_terms: D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D018450:Disease Progression; D004305:Dose-Response Relationship, Drug; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D019694:Hepatitis B, Chronic / Q000097:blood / Q000188:drug therapy* / Q000473:pathology*; D006801:Humans; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome; D005719:gamma-Globulins / Q000378:metabolism
chemical_list: D015415:Biomarkers; D005938:Glucocorticoids; D005719:gamma-Globulins; D011241:Prednisone