title: Pathological changes in the sinoatrial node tissues of rats caused by pulsed microwave exposure.
abstract: To observe microwave induced dynamic pathological changes in the sinus nodes, wistar rats were exposed to 0, 5, 10, 50 mW/cm2 microwave. In 10 and 50 mW/cm2 groups, disorganized sinoatrial node cells, cell swelling, cytoplasmic condensation, nuclear pyknosis, and anachromasis, swollen, and empty mitochondria, and blurred and focally dissolved myofibrils could be detected from 1 to 28 d, while reduced parenchymal cells, increased collagen fibers, and extracellular matrix remodeling of interstitial cells were observed from 6 to 12 months. In conclusion, 10 and 50 mW/cm2 microwave could cause structural damages in the sinoatrial node and extracellular matrix remodeling in rats.
authors.affiliation: Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing 100850, China; The Affiliated Hospital of Logistic College of Chinese People's Armed Police Forces, Tianjin 300162, China.
authors.forename: Yan Qing
authors.initials: YQ
authors.lastname: Liu
authors.affiliation: Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Ya Bing
authors.initials: YB
authors.lastname: Gao
authors.affiliation: Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Ji
authors.initials: J
authors.lastname: Dong
authors.affiliation: Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Bin Wei
authors.initials: BW
authors.lastname: Yao
authors.affiliation: Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhao
authors.affiliation: Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
authors.forename: Rui Yun
authors.initials: RY
authors.lastname: Peng
mesh_terms: D000818:Animals; D005109:Extracellular Matrix / Q000473:pathology / Q000528:radiation effects; D008297:Male; D008872:Microwaves / Q000009:adverse effects*; D051381:Rats; D017208:Rats, Wistar; D012849:Sinoatrial Node / Q000473:pathology / Q000528:radiation effects*