title: A fluorescent nanosensor based on graphene quantum dots-aptamer probe and graphene oxide platform for detection of lead (II) ion.
abstract: The sensitive detection of heavy metal ions in the organism and aquatic ecosystem using nanosensors based on environment friendly and biocompatible materials still remains a challenge. A fluorescent turn-on nanosensor for lead (II) detection based on biocompatible graphene quantum dots and graphene oxide by employment of Pb(2+)-induced G-quadruplex formation was reported. Graphene quantum dots with high quantum yield, good biocompatibility were prepared and served as the fluorophore of Pb(2+) probe. Fluorescence turn-off of graphene quantum dots is easily achieved through efficient photoinduced electron transfer between graphene quantum dots and graphene oxide, and subsequent fluorescence turn-on process is due to the formation of G-quadraplex aptamer-Pb(2+) complex triggered by the addition of Pb(2+). This nanosensor can distinguish Pb(2+) ion from other ions with high sensitivity and good reproducibility. The detection method based on this nanosensor possesses a fast response time of one minute, a broad linear span of up to 400.0 nM and ultralow detection limit of 0.6 nM.
authors.affiliation: College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China.
authors.forename: Zhao Sheng
authors.initials: ZS
authors.lastname: Qian
authors.affiliation: College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China.
authors.forename: Xiao Yue
authors.initials: XY
authors.lastname: Shan
authors.affiliation: College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China.
authors.forename: Lu Jing
authors.initials: LJ
authors.lastname: Chai
authors.affiliation: College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China.
authors.forename: Jian Rong
authors.initials: JR
authors.lastname: Chen
authors.affiliation: College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China. Electronic address: fenghui@zjnu.cn.
authors.forename: Hui
authors.initials: H
authors.lastname: Feng
mesh_terms: D015374:Biosensing Techniques; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes; D054856:G-Quadruplexes; D006108:Graphite / Q000737:chemistry; D007477:Ions / Q000737:chemistry / Q000302:isolation & purification*; D007854:Lead / Q000737:chemistry / Q000302:isolation & purification*; D009841:Oligonucleotides / Q000737:chemistry; D010087:Oxides / Q000737:chemistry; D045663:Quantum Dots / Q000737:chemistry; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D005456:Fluorescent Dyes; D007477:Ions; D009841:Oligonucleotides; D010087:Oxides; D014874:Water Pollutants, Chemical; D007854:Lead; D006108:Graphite
keywords: Graphene oxide; Graphene quantum dots; Nanosensor; Pb(2+) detection