title: Nausea, vomiting and quality of life of patients with cancer undergoing antineoplastic treatment: an evaluation by pharmacists.
abstract: OBJECTIVE
  This study aims to evaluate the frequency and severity of nausea and vomiting using two different instruments and relate them to quality of life (QOL) in patients with cancer receiving antineoplastic treatment.
  
  
  METHODS
  Severity of chemotherapy-induced nausea and vomiting (CINV) was measured by Common Terminology Criteria for Adverse Events (CTCAE) and a numerical scale. QOL was assessed using the Functional Assessment of Cancer Therapy-General questionnaire.
  
  
  RESULTS
  Of the 50 patients studied, 60.0% reported nausea (40.0% CTCAE grade 1; 66.7% moderate intensity on numerical scale) and 30.0% reported vomiting (46.7% CTCAE grades 1 and 2, each; 66.7% moderate intensity on numerical scale). CINV did not influence overall QOL.
  
  
  CONCLUSIONS
  The frequency of CINV was high. There was no association between nausea/vomiting and overall QOL.
authors.affiliation: Department of Clinical Pathology, School of Medical Sciences (FCM), University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors.forename: Cinthia Madeira
authors.initials: CM
authors.lastname: de Souza
authors.affiliation: Department of Clinical Pathology, School of Medical Sciences (FCM), University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors.forename: Marília Berlofa
authors.initials: MB
authors.lastname: Visacri
authors.affiliation: Department of Clinical Pathology, School of Medical Sciences (FCM), University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors.forename: Graziele Baldan
authors.initials: GB
authors.lastname: Ferrari
authors.affiliation: Department of Clinical Pathology, School of Medical Sciences (FCM), University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors.forename: Bruna Taliani
authors.initials: BT
authors.lastname: Tuan
authors.affiliation: Department of Clinical Pathology, School of Medical Sciences (FCM), University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors.forename: Anna Paula Lourenço
authors.initials: AP
authors.lastname: Costa
authors.affiliation: Chemotherapy Preparation Unit, Hospital of Clinics, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors.forename: Cristina Rosa
authors.initials: CR
authors.lastname: Barbosa
authors.affiliation: Department of Clinical Medicine, School of Medical Sciences (FCM), University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors.forename: Carmen Silvia P
authors.initials: CS
authors.lastname: Lima
authors.affiliation: Department of Clinical Pathology, School of Medical Sciences (FCM), University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors.forename: Priscila Gava
authors.initials: PG
authors.lastname: Mazzola
authors.affiliation: Department of Clinical Pathology, School of Medical Sciences (FCM), University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
authors.forename: Patrícia
authors.initials: P
authors.lastname: Moriel
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D001938:Brazil / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D009369:Neoplasms / Q000150:complications / Q000188:drug therapy*; D010595:Pharmacists; D011788:Quality of Life; D012720:Severity of Illness Index; D014839:Vomiting / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology
chemical_list: D000970:Antineoplastic Agents
keywords: antineoplastic treatment; nausea; pharmacists; quality of life; vomiting