title: HBV and HCV Coinfection among HIV/AIDS Patients in the National Hospital of Tropical Diseases, Vietnam.
abstract: Aim. To examine prevalence and characterization of HBV and HCV coinfection among HIV/AIDS patients. Methods. This cross-sectional, retrospective study analyzed 724 HIV/AIDS patients in the HIV clinic at the National Hospital of Tropical Diseases (NHTD), from 5/2005 to 4/2011. Results. The prevalence of HBV, HCV, and HIV coinfection was 50.3% (364/724), of which HbsAg, HCV, and both of HbsAg, and HCV positivity were 8.4%, 35.4%, and 6.5%, respectively. The cohort (364 patients) with HBV, HCV, and HIV coinfection live in the 30 provinces/cities in the North and Central area of Vietnam. We found statistically significant associations between heightened risk of coinfection with HIV and HCV in the age group 30-39 years (P < 0.001), male gender (P < 0.001), never married patients (P < 0.001), patients with a history of injection drug use (P < 0.001), and clinical stages 2-4 (P < 0.001). Coinfection with HBV/HIV was statistically significant associations between heightened risk of marital status (never married) (P < 0.001) and those who reported transmission through sexual intercourse. Conclusion. Coinfection with viral hepatitis is common in HIV patients; further study of the impact and evolution of coinfection is necessary to find effective treatment algorithms.
authors.affiliation: Hanoi Medical University, Hanoi 10000, Vietnam.
authors.forename: Bùi Vũ
authors.initials: BV
authors.lastname: Huy
authors.affiliation: Hanoi Medical University, Hanoi 10000, Vietnam.
authors.forename: Kanxay
authors.initials: K
authors.lastname: Vernavong
authors.affiliation: National Hospital of Tropical Diseases, 78 Giai Phong Road, Dong Da District, Hanoi 10000, Vietnam.
authors.forename: Nguyễn Văn
authors.initials: NV
authors.lastname: Kính