title: Successful use of extracorporeal membrane oxygenation for respiratory failure caused by mediastinal precursor T lymphoblastic lymphoma.
abstract: Precursor T lymphoblastic lymphoma (T-LBL) often manifests as a mediastinal mass sometimes compressing vital structures like vessels or large airways. This case was a 40-year-old male who developed T-LBL presenting as respiratory failure caused by mediastinal T-LBL. He presented with persistent life threatening hypoxia despite tracheal intubation. We successfully managed this respiratory failure using venovenous (VV) ECMO. Induction chemotherapy was started after stabilizing oxygenation and the mediastinal lesion shrank rapidly. Respiratory failure caused by compression of the central airway by tumor is an oncologic emergency. VV ECMO may be an effective way to manage this type of respiratory failure as a bridge to chemotherapy.
authors.affiliation: Department of Hematology and Medical Oncology, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan.
authors.forename: Masafumi
authors.initials: M
authors.lastname: Oto
authors.affiliation: Department of General Internal Medicine, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Inadomi
authors.affiliation: Department of General Internal Medicine, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Chosa
authors.affiliation: Department of Hematology and Medical Oncology, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan.
authors.forename: Shima
authors.initials: S
authors.lastname: Uneda
authors.affiliation: Department of General Internal Medicine, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan.
authors.forename: Soichi
authors.initials: S
authors.lastname: Uekihara
authors.affiliation: Department of Hematology and Medical Oncology, Japanese Red Cross Kumamoto Hospital, 2-1-1 Nagamine-minami, Higashi-Ku, Kumamoto 861-8520, Japan.
authors.forename: Minoru
authors.initials: M
authors.lastname: Yoshida