title: p21-activated kinase 4: a druggable target in the elusive oncogenic KRAS pathway?
authors.affiliation: Department of Oncology, Wayne State University School of Medicine, 4100 John R, HWCRC 732, Detroit, MI 48201, USA.
authors.forename: Asfar S
authors.initials: AS
authors.lastname: Azmi
authors.forename: Ramzi M
authors.initials: RM
authors.lastname: Mohammad
mesh_terms: D000494:Allosteric Regulation; D006801:Humans; D010190:Pancreatic Neoplasms / Q000378:metabolism / Q000473:pathology; D047428:Protein Kinase Inhibitors / Q000737:chemistry / Q000378:metabolism; D015398:Signal Transduction; D054462:p21-Activated Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D018631:ras Proteins / Q000737:chemistry / Q000378:metabolism*
chemical_list: D047428:Protein Kinase Inhibitors; D054462:p21-Activated Kinases; D018631:ras Proteins
keywords: KRAS; PAK; PAK4; Ras; allosteric modulators; pancreatic cancer; small molecule drugs; small molecule inhibitors