title: Primary breast cancer in the elderly: a systematic literature review on histological type and clinical outcome.
abstract: The objective was to determine whether histological types of breast cancer in elderly women influence clinical outcome. Four major databases were searched. All relevant articles, from January 1990 to December 2013, were screened. After applying inclusion and exclusion criteria, 11 studies were included. Invasive ductal carcinoma was the commonest (68.5-87.1%) histological type, followed by lobular carcinoma (6.9-17.7%). Four studies reported on survival. However, none specifically looked at survival according to different histological types. There are very little data on the influence of histological type on clinical outcome in primary breast cancer in elderly patients. Further studies may elucidate any potential influence and its relationship with tumor biology.
authors.affiliation: School of Medicine, University of Nottingham, Nottingham, UK.
authors.forename: Samuel O
authors.initials: SO
authors.lastname: Ogunbiyi
authors.forename: Sooyoung
authors.initials: S
authors.lastname: Lee
authors.forename: John
authors.initials: J
authors.lastname: Mathew
authors.forename: Kwok Leung
authors.initials: KL
authors.lastname: Cheung
mesh_terms: D000367:Age Factors; D001943:Breast Neoplasms / Q000401:mortality / Q000628:therapy*; D018270:Carcinoma, Ductal, Breast / Q000401:mortality / Q000628:therapy*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D016896:Treatment Outcome
keywords: elderly woman; histological type; outcome; primary breast cancer