title: Improving Adherence to Evidence-Based Guidelines for Chemotherapy-Induced Nausea and Vomiting.
abstract: Chemotherapy-induced nausea and vomiting (CINV) is one of the most common side effects experienced by patients receiving chemotherapy. Antiemetic medications can be used to effectively prevent and treat CINV. Choice and dose of antiemetics are often based on provider preference rather than evidenced-based information. CINV antiemetic prescribing guidelines provide an evidence-based approach and standardization for the management of this common side effect. The purpose of this quality improvement project was to improve adherence to CINV antiemetic guidelines. Despite distribution of CINV guidelines, there was inconsistent compliance with their use. When providers reported unfamiliarity with the guidelines, they were reintroduced and direct provider feedback was given to improve adherence. This quality improvement project demonstrates the need for continued reinforcement to sustain change that results in the best care for children experiencing CINV.
authors.affiliation: Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA Margaret.t.wood@vanderbilt.edu.
authors.forename: Margaret
authors.initials: M
authors.lastname: Wood
authors.affiliation: Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Hall
authors.affiliation: Duke University, Durham, NC, USA.
authors.forename: Marilyn
authors.initials: M
authors.lastname: Hockenberry
authors.affiliation: Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA.
authors.forename: Scott
authors.initials: S
authors.lastname: Borinstein
mesh_terms: D000293:Adolescent; D000328:Adult; D000932:Antiemetics / Q000627:therapeutic use*; D002648:Child; D064420:Drug-Related Side Effects and Adverse Reactions / Q000188:drug therapy; D055318:Evidence-Based Nursing / Q000592:standards; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced* / Q000188:drug therapy*; D009369:Neoplasms / Q000188:drug therapy*; D009859:Oncology Nursing / Q000592:standards; D010353:Patient Education as Topic; D010371:Pediatric Nursing / Q000592:standards; D017410:Practice Guidelines as Topic; D011446:Prospective Studies; D015144:Southeastern United States; D014839:Vomiting / Q000139:chemically induced* / Q000188:drug therapy*; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D000932:Antiemetics
keywords: antiemetics; chemotherapy; nausea; sustainability; vomiting