title: Natural compounds for solar photoprotection: a patent review.
abstract: BACKGROUND
  Ultraviolet irradiation has deleterious effects on human skin, including tanning, sunburn, cancer and connective tissue degradation (photoaging). Botanical antioxidants have been shown to be associated with reduced incidence of photocarcinogenesis and photoaging through their photoprotective profile.
  
  
  METHODS
  Here, the authors summarized therapeutic patent applications concerning the employment of medicinal plants on the technological development of a formulation with photoprotective or photoaging application. So, the patent search was conducted in the databases WIPO, Espacenet, USPTO and Derwent, using the keywords - photoaging, photoprotection and the IPC A61K 8/97 (cosmetics or similar cleaning supplies obtained from vegetable origin, for example, plant extracts) and A61K 36/00 (medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, for example, traditional herbal medicines). We found 180 patents, out of which 25 were evaluated using inclusion criteria as application of natural products with photoprotective or photoaging application.
  
  
  CONCLUSIONS
  We found that some patents related to the cosmetic compositions for improving skin wrinkle and either preventing or reducing the signs of photoaging and sunburn. The cosmetic compositions are manufactured in the form of a lotion, gel, soluble liquid, cream, essence, oil-in-water-type or water-in-oil-type formulation, containing the vegetal extracts as an active ingredient.
authors.affiliation: Federal University of Sergipe, Department of Pharmacy , Lagarto, SE , Brazil.
authors.forename: Mairim R
authors.initials: MR
authors.lastname: Serafini
authors.forename: Adriana G
authors.initials: AG
authors.lastname: Guimarães
authors.forename: Jullyana S S
authors.initials: JS
authors.lastname: Quintans
authors.forename: Adriano A S
authors.initials: AA
authors.lastname: Araújo
authors.forename: Paula S
authors.initials: PS
authors.lastname: Nunes
authors.forename: Lucindo J
authors.initials: LJ
authors.lastname: Quintans-Júnior
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology; D003358:Cosmetics / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D010330:Patents as Topic; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry; D012867:Skin / Q000187:drug effects / Q000528:radiation effects; D015595:Skin Aging / Q000187:drug effects / Q000528:radiation effects; D012878:Skin Neoplasms / Q000209:etiology / Q000517:prevention & control; D013473:Sunscreening Agents / Q000302:isolation & purification / Q000494:pharmacology*; D014466:Ultraviolet Rays / Q000009:adverse effects
chemical_list: D000975:Antioxidants; D003358:Cosmetics; D010936:Plant Extracts; D013473:Sunscreening Agents
keywords: antioxidant; cancer; natural products; photoaging; photoprotective