title: PLEKHM1: a multiprotein adaptor for the endolysosomal system.
abstract: Two papers by McEwan et al. (McEwan et al., 2015a, 2015b) identify interactions of PLEKHM1 with autophagosome-associated Atg8 proteins and Salmonella typhimurium effector, SifA, linking autophagy and the Salmonella-containing vacuole (SCV) to the endolysosomal Rab7/HOPS-regulated tethering machinery.
authors.affiliation: Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot 7610001, Israel.
authors.forename: Moran
authors.initials: M
authors.lastname: Rawet-Slobodkin
authors.affiliation: Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: zvulun.elazar@weizmann.ac.il.
authors.forename: Zvulun
authors.initials: Z
authors.lastname: Elazar
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics*; D000818:Animals; D051017:Apoptosis Regulatory Proteins; D000071183:Autophagy-Related Proteins; D006801:Humans; D008247:Lysosomes / Q000378:metabolism*; D008561:Membrane Fusion / Q000235:genetics*; D008562:Membrane Glycoproteins / Q000235:genetics*; D008869:Microtubule-Associated Proteins / Q000235:genetics*; D010588:Phagosomes / Q000378:metabolism*
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D051017:Apoptosis Regulatory Proteins; D000071183:Autophagy-Related Proteins; C116741:GABARAP protein, human; C477012:MAP1LC3A protein, human; D008562:Membrane Glycoproteins; D008869:Microtubule-Associated Proteins; C476215:PLEKHM1 protein, human