title: Real clinical practice of catheter therapy for deep venous thrombosis: periprocedural and 6-month outcomes from the EDO registry.
abstract: A recent national study in Japan indicated that 5.8 % of deep venous thrombosis (DVT) patients were treated using endovascular procedures, 83 % of which included catheter-directed thrombolysis (CDT). However, the details of these endovascular procedures and their outcomes have not yet been fully evaluated. Using DVT data from the EDO registry (EnDOvascular treatment registry) database, a total of 35 symptomatic iliac or femoral DVT patients who received endovascular treatment (54.3 % male, age 64.7 ± 15.1) were analyzed. The dominant patient risks were being bedridden (22.9 %) and May-Thurner syndrome (25.7 %). Approximately 77.1 % of patients were treated using an antegrade approach, and CDT and other endovascular procedures were performed in 82.9 and 57.1 % of patients, respectively. A periprocedural inferior vena cava (IVC) filter was used in 94.1 % of patients, which remained implanted in 37.1 and 20.0 % of patients after discharge and 6 months after hospitalization, respectively. After 6 months of treatment, 2.9 % of patients experienced a recurrence of DVT and 5.7 % suffered revascularization, but no patient had a recurrence of pulmonary embolism. Subjective symptoms improved in 80.0 % of patients, while 2.9 % of patients felt worse at 6 months after treatment. Postthrombotic syndrome-related symptoms were observed in seven patients (19.4 %), and edema was most frequently observed (71.4 %). The details of CDT procedures, such as approach site and the removal of the IVC filter, varied among hospitals. Despite improved symptoms, further procedural standardization and data collection should be conducted to reduce complications and improve outcomes.
authors.affiliation: Department of Cardiology, St. Luke's International Hospital, 9-1, Akashi-cho, Chuo-ku, Tokyo, Japan, atmizu@gmail.com.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Mizuno
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Anzai
authors.forename: Makoto
authors.initials: M
authors.lastname: Utsunomiya
authors.forename: Junji
authors.initials: J
authors.lastname: Yajima
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ohta
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ando
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Umemoto
authors.forename: Michiaki
authors.initials: M
authors.lastname: Higashitani
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Ozaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sakamoto
authors.forename: Masashi
authors.initials: M
authors.lastname: Nakao
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Yuzawa
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Kaneko
authors.forename: Masato
authors.initials: M
authors.lastname: Nakamura
mesh_terms: D019992:Databases as Topic; D004487:Edema / Q000209:etiology; D057510:Endovascular Procedures / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data*; D005260:Female; D005263:Femoral Artery; D006801:Humans; D007083:Iliac Artery; D008297:Male; D062108:May-Thurner Syndrome / Q000150:complications; D061185:Mechanical Thrombolysis; D008875:Middle Aged; D010690:Phlebography; D012008:Recurrence; D012042:Registries; D012307:Risk Factors; D016896:Treatment Outcome; D016306:Vena Cava Filters; D014682:Vena Cava, Inferior; D020246:Venous Thrombosis / Q000628:therapy*