title: First isolation and genomic characterization of enterovirus A71 and coxsackievirus A16 from hand foot and mouth disease patients in the Lao PDR.
abstract: Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are major aetiological agents of hand, foot and mouth disease in Asia. We established the first genomic characterization of strains isolated in 2011 from Lao patients. Isolates were related to EV-A71 genotype C4 and CV-A16 genotype B1a that circulated in neighbouring countries during the same period. This confirms the regional character of hand, foot and mouth disease epidemiology and makes plausible the occurrence of severe disease in the Lao population.
authors.affiliation: Aix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health ; IHU Méditerranée Infection, APHM Public Hospitals of Marseille Marseille, France.
authors.forename: V H
authors.initials: VH
authors.lastname: Nguyen
authors.affiliation: Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital Vientiane, Lao PDR.
authors.forename: B
authors.initials: B
authors.lastname: Sibounheuang
authors.affiliation: Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital Vientiane, Lao PDR.
authors.forename: K
authors.initials: K
authors.lastname: Phommasone
authors.affiliation: Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital Vientiane, Lao PDR.
authors.forename: M
authors.initials: M
authors.lastname: Vongsouvath
authors.affiliation: Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital Vientiane, Lao PDR ; Centre for Tropical Medicine, Nuffield Department of Medicine, Churchill Hospital, University of Oxford Oxford, United Kingdom.
authors.forename: P N
authors.initials: PN
authors.lastname: Newton
authors.affiliation: Aix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health ; IHU Méditerranée Infection, APHM Public Hospitals of Marseille Marseille, France.
authors.forename: G
authors.initials: G
authors.lastname: Piorkowski
authors.affiliation: Aix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health.
authors.forename: C
authors.initials: C
authors.lastname: Baronti
authors.affiliation: Aix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health ; IHU Méditerranée Infection, APHM Public Hospitals of Marseille Marseille, France.
authors.forename: X
authors.initials: X
authors.lastname: de Lamballerie
authors.affiliation: Aix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health ; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital Vientiane, Lao PDR ; Centre for Tropical Medicine, Nuffield Department of Medicine, Churchill Hospital, University of Oxford Oxford, United Kingdom.
authors.forename: A
authors.initials: A
authors.lastname: Dubot-Pérès
keywords: Coxsackievirus A16; enterovirus A71; genome sequence; hand, foot and mouth disease