title: Recurrent pigmented villonodular synovitis and multifocal giant cell tumor of the tendon sheath: case report.
abstract: Intra- and extra-articular giant cell tumor of tendon sheath (GCTTS) and pigmented villonodular synovitis (PVNS) are histologically similar, usually benign tumors that can be characterized by synovial involvement (GCTTS) or overgrowth (PVNS). These tumors are most often found in the knee and digits of the hand. Although recurrence is a common feature of both conditions, multifocal lesions are rare. We present an unusual case of multifocal, recurrent, bilateral GCTTS/PVNS involving both upper and lower extremities. Recurrent right ankle and right index finger masses, in addition to masses on the right small finger and left thumb, were excised over a 14-year period.
authors.affiliation: Division of Hand and Upper Extremity Surgery, Hospital for Special Surgery, New York, NY, USA; Department of Pathology, Hospital for Special Surgery, New York, NY, USA; Weill Medical College of Cornell University, New York, NY, USA; School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Orthopaedics & Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.
authors.forename: Jung-Pan
authors.initials: JP
authors.lastname: Wang
authors.affiliation: Division of Hand and Upper Extremity Surgery, Hospital for Special Surgery, New York, NY, USA; Department of Pathology, Hospital for Special Surgery, New York, NY, USA; Weill Medical College of Cornell University, New York, NY, USA; School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Orthopaedics & Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.
authors.forename: Schneider K
authors.initials: SK
authors.lastname: Rancy
authors.affiliation: Division of Hand and Upper Extremity Surgery, Hospital for Special Surgery, New York, NY, USA; Department of Pathology, Hospital for Special Surgery, New York, NY, USA; Weill Medical College of Cornell University, New York, NY, USA; School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Orthopaedics & Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan.
authors.forename: Edward F
authors.initials: EF
authors.lastname: DiCarlo
authors.affiliation: Division of Hand and Upper Extremity Surgery, Hospital for Special Surgery, New York, NY, USA; Department of Pathology, Hospital for Special Surgery, New York, NY, USA; Weill Medical College of Cornell University, New York, NY, USA; School of Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Orthopaedics & Traumatology, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address: wolfes@hss.edu.
authors.forename: Scott W
authors.initials: SW
authors.lastname: Wolfe
mesh_terms: D000328:Adult; D000843:Ankle Joint / Q000000981:diagnostic imaging / Q000473:pathology; D001707:Biopsy, Needle; D005260:Female; D005384:Finger Joint / Q000000981:diagnostic imaging / Q000473:pathology; D005500:Follow-Up Studies; D005870:Giant Cell Tumors / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D009361:Neoplasm Invasiveness / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D009367:Neoplasm Staging; D011859:Radiography; D035583:Rare Diseases; D012008:Recurrence; D018570:Risk Assessment; D013586:Synovitis, Pigmented Villonodular / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
keywords: Giant cell tumor of tendon sheath; multifocal; pigmented villonodular synovitis; recurrent