title: Personalized alerts for patients with COPD using pulse oximetry and symptom scores.
abstract: Chronic Obstructive Pulmonary Disease (COPD) is a progressive chronic disease, predicted to become the third leading cause of death by 2030. COPD patients are at risk of sudden and acute worsening of symptoms, reducing the patient's quality of life and leading to hospitalization. We present the results of a pilot study with 18 COPD patients using an m-Health system, based on a tablet computer and pulse oximeter, for a period of six months. For prioritizing patients for clinical review, a data-driven approach has been developed which generates personalized alerts using the electronic symptom diary, pulse rate, blood oxygen saturation, and respiratory rate derived from oximetry data. This work examines the advantages of multivariate novelty detection over univariate approaches and shows the benefit of including respiratory rate as a predictor.
authors.forename: Syed Ahmar
authors.initials: SA
authors.lastname: Shah
authors.forename: Carmelo
authors.initials: C
authors.lastname: Velardo
authors.forename: Oliver J
authors.initials: OJ
authors.lastname: Gibson
authors.forename: Heather
authors.initials: H
authors.lastname: Rutter
authors.forename: Andrew
authors.initials: A
authors.lastname: Farmer
authors.forename: Lionel
authors.initials: L
authors.lastname: Tarassenko
mesh_terms: D000368:Aged; D000465:Algorithms; D019540:Area Under Curve; D002908:Chronic Disease; D056902:Clinical Alarms; D034201:Computers, Handheld; D005260:Female; D006339:Heart Rate; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010092:Oximetry / Q000379:methods*; D010100:Oxygen / Q000097:blood; D010865:Pilot Projects; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D011788:Quality of Life; D056152:Respiratory Rate; D012189:Retrospective Studies; D012815:Signal Processing, Computer-Assisted; D012984:Software; D014584:User-Computer Interface
chemical_list: D010100:Oxygen