title: Techniques and applications of dynamic contrast enhanced magnetic resonance imaging in cancer.
abstract: We first discuss several key technical issues associated with quantitative dynamic contrast enhanced magnetic resonance imaging (DCE-MRI), and then provide examples of DCE-MRI in oncology. In particular, we examine the importance of both active and passive delivery of the contrast agent to the tissue under investigation, and repeatability/reproducibility in DCE-MRI studies. We then discuss examples of how DCE-MRI can assist in assessing and predicting therapeutic response in the neoadjuvant setting.
authors.forename: Stephanie L
authors.initials: SL
authors.lastname: Barnes
authors.forename: Jennifer G
authors.initials: JG
authors.lastname: Whisenant
authors.lastname: Xia Li
authors.forename: Thomas E
authors.initials: TE
authors.lastname: Yankeelov
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D017024:Chemotherapy, Adjuvant; D003287:Contrast Media / Q000008:administration & dosage / Q000493:pharmacokinetics; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D020360:Neoadjuvant Therapy; D015203:Reproducibility of Results; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media