title: [Benefit assessment of operative interventions from the perspective of surgical research].
abstract: The benefit assessment of surgical procedures serves as the basis for the concept of evidence-based surgery. However, especially in the field of surgery, many interventions are lacking assessment in high-quality clinical trials. Therefore, a well-structured benefit assessment of surgical interventions in the future is imperative. Considering the different perspectives, e.g. of the patients, surgeons, industry or health care investors, the implications of the benefits and risks of a procedure can differ significantly. Researchers have to abide by different regulations, depending on the type of intervention being evaluated in a surgical trial. Furthermore, the benefit assessment of surgical procedures poses specific challenges, from the choice of a relevant endpoint to issues concerning the standardization of the interventions and the impact of learning curves. The IDEAL concept, which was established by a group of international experts in 2009, serves as a framework for the future development and assessment of innovations in the field of surgery. For example, the SDGC (Study Center of the German Society of Surgery) and CHIR-Net (Surgical Studies Network) indicate that such collaborations of clinicians and methodologists can lead to the creation of a qualified structure for the effective benefit assessment of surgical procedures. In the future, the aforementioned evidence gaps must be eliminated and innovations evaluated efficiently by the work of such networks.
authors.affiliation: Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Universität Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.
authors.forename: F J
authors.initials: FJ
authors.lastname: Hüttner
authors.forename: A
authors.initials: A
authors.lastname: Ulrich
authors.forename: A L
authors.initials: AL
authors.lastname: Mihaljevic
authors.forename: P
authors.initials: P
authors.lastname: Probst
authors.forename: I
authors.initials: I
authors.lastname: Rossion
authors.forename: Markus K
authors.initials: MK
authors.lastname: Diener
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration*; D002986:Clinical Trials as Topic / Q000379:methods*; D003362:Cost-Benefit Analysis / Q000379:methods / Q000458:organization & administration*; D019317:Evidence-Based Medicine / Q000379:methods / Q000458:organization & administration; D005858:Germany; D017063:Outcome Assessment, Health Care / Q000379:methods*; D018570:Risk Assessment / Q000458:organization & administration*; D013514:Surgical Procedures, Operative / Q000145:classification*; D016896:Treatment Outcome