title: Amyloidosis in Behcet's disease.
abstract: Behcet's disease (BD) is a multisystem vasculitis with protean manifestations. It is characterized by a heightened state of inflammation, although the factors that initiate and sustain this inflammation are not clear. We report some cases of BD-associated amyloidosis and have similar features. The patients developed nephrotic syndrome due to secondary amyloidosis, which was refractory to the immunosuppressive agents. Two patients expired and the third was lost to follow-up during the course. The BD complicated with amyloidosis is associated with high mortality despite the current aggressive therapy.
authors.affiliation: Department of Internal Medicine, La Rabta Hospital, Tunis, Tunisia.
authors.forename: I Ben
authors.initials: IB
authors.lastname: Ghorbel
authors.forename: Nabil
authors.initials: N
authors.lastname: Belfeki
authors.forename: T Ben
authors.initials: TB
authors.lastname: Salem
authors.forename: M
authors.initials: M
authors.lastname: Lamloum
authors.forename: M H
authors.initials: MH
authors.lastname: Houman
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications* / Q000188:drug therapy; D001528:Behcet Syndrome / Q000150:complications* / Q000188:drug therapy; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000209:etiology*