title: Development of a handheld fluorescence imaging camera for intraoperative sentinel lymph node mapping.
abstract: We present a compact fluorescence imaging system developed for real-time sentinel lymph node mapping. The device uses two near-infrared wavelengths to record fluorescence and anatomical images with a single charge-coupled device camera. Experiments on lymph node and tissue phantoms confirmed that the amount of dye in superficial lymph nodes can be better estimated due to the absorption correction procedure integrated in our device. Because of the camera head's small size and low weight, all accessible regions of tissue can be reached without the need for any adjustments.
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Szyc
authors.forename: Stefanie
authors.initials: S
authors.lastname: Bonifer
authors.forename: Alfred
authors.initials: A
authors.lastname: Walter
authors.forename: Uwe
authors.initials: U
authors.lastname: Jagemann
authors.forename: Dirk
authors.initials: D
authors.lastname: Grosenick
authors.forename: Rainer
authors.initials: R
authors.lastname: Macdonald
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology*; D003196:Computer Graphics; D003198:Computer Simulation; D003287:Contrast Media / Q000737:chemistry; D004058:Diffusion; D004867:Equipment Design; D005260:Female; D006801:Humans; D007208:Indocyanine Green / Q000737:chemistry; D008198:Lymph Nodes / Q000473:pathology*; D061848:Optical Imaging / Q000295:instrumentation* / Q000379:methods*; D019047:Phantoms, Imaging; D021701:Sentinel Lymph Node Biopsy / Q000295:instrumentation* / Q000379:methods*; D012878:Skin Neoplasms / Q000473:pathology*; D019265:Spectroscopy, Near-Infrared; D014584:User-Computer Interface; D014867:Water / Q000737:chemistry
chemical_list: D003287:Contrast Media; D014867:Water; D007208:Indocyanine Green