title: [Antimicrobial efficacy of systemic antibiotics of different groups in the complex treatment of patients with chronic periodontal disease].
abstract: Among microorganisms found in the oral cavity there are several kinds of periodontopathogenic bacteria having higher adhesive, invasive and toxic properties. Eighty patients with moderate and severe chronic generalized periodontitis were included in the study. The choice of treatment regimen depended on real-time PCR values of pathogenic microorganisms in periodontal pockets. Data on composition of periodontal pockets microflora by moderate and severe periodontal disease allow prompt target antimicrobial therapy.
authors.affiliation: FGBU Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii Minzdrava Rossii, Moskva; GBOU VPO Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova, Moskva.
authors.forename: O A
authors.initials: OA
authors.lastname: Zorina
authors.affiliation: FGBU Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii Minzdrava Rossii, Moskva; GBOU VPO Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova, Moskva.
authors.forename: I S
authors.initials: IS
authors.lastname: Berkutova
authors.affiliation: FGBU Tsentral'nyĭ nauchno-issledovatel'skiĭ institut stomatologii i cheliustno-litsevoĭ khirurgii Minzdrava Rossii, Moskva; GBOU VPO Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova, Moskva.
authors.forename: A A
authors.initials: AA
authors.lastname: Basova
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D055113:Chronic Periodontitis / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology; D010514:Periodontal Pocket / Q000188:drug therapy* / Q000382:microbiology; D060888:Real-Time Polymerase Chain Reaction; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents