title: Aspect of thrombolytic therapy: a review.
abstract: Thrombolytic therapy, also known as clot busting drug, is a breakthrough treatment which has saved untold lives. It has been used in the clinical area to treat venous and arterial thromboembolic complaints which are a foremost cause of death. In 1761, Morgagni lead the way of thrombolytic therapy. Now day's different types of thrombolytic drugs are currently available in market: alteplase, anistreplase, urokinase, streptokinase, tenecteplase, and so forth. Thrombolytic therapy should be given with maintaining proper care in order to minimize the risk of clinically important bleeding as well as enhance the chances of successfully thrombolysis of clot. These cares include preinfusion care, during the infusion care, and postinfusion care. Besides proper knowledge of contraindication, evolutionary factor, and combination of drug is essential for successful thrombolytic therapy. In these review we discussed about these aspect of thrombolytic therapy.
authors.affiliation: Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali 3814, Bangladesh.
authors.forename: Md Ramjan
authors.initials: MR
authors.lastname: Ali
authors.affiliation: Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali 3814, Bangladesh.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Salim Hossain
authors.affiliation: Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali 3814, Bangladesh.
authors.forename: Md Ariful
authors.identifier: 0000-0002-1505-332X
authors.initials: MA
authors.lastname: Islam
authors.affiliation: Department of Pharmacy, University of Rajshahi, Rajshahi 6205, Bangladesh.
authors.forename: Md
authors.initials: M
authors.lastname: Saiful Islam Arman
authors.affiliation: Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali 3814, Bangladesh.
authors.forename: Golam
authors.initials: G
authors.lastname: Sarwar Raju
authors.affiliation: Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali 3814, Bangladesh.
authors.forename: Prianka
authors.initials: P
authors.lastname: Dasgupta
authors.affiliation: Department of Pharmacy, Noakhali Science and Technology University, Sonapur, Noakhali 3814, Bangladesh.
authors.forename: Tasnim Fariha
authors.initials: TF
authors.lastname: Noshin
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D005343:Fibrinolytic Agents / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D015912:Thrombolytic Therapy
chemical_list: D005343:Fibrinolytic Agents