title: Serum insulin is significantly related to components of the metabolic syndrome in Japanese working women.
abstract: BACKGROUND
  The aim of this study was to examine the association between serum insulin levels and components of the metabolic syndrome (MetS) in working women.
  
  
  METHODS
  The target subjects were 141 working women. Serum triglyceride, HDL cholesterol, uric acid, plasma insulin and plasma glucose were measured in addition to waist circumference and blood pressure.
  
  
  RESULTS
  MetS was diagnosed based on the modified criteria of the International Diabetes Federation, and was present in 7.1% (10/141) of the study subjects. Stepwise multiple regression analysis showed that some components of MetS were significantly associated with log-transformed values of the serum insulin. The standardized regression coefficient for the waist circumference, high density lipoprotein cholesterol, systolic blood pressure and age were 0.238, -0.333, 0.309 and -0.156, respectively.
  
  
  CONCLUSIONS
  A statistically significant relationship existed between the components of MetS and the serum insulin levels in working women.
authors.affiliation: Department of Hygiene and Public Health, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-Ku, Tokyo 113-8602, Japan.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Kawada
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Otsuka
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Inagaki
authors.forename: Yoko
authors.initials: Y
authors.lastname: Wakayama
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
authors.forename: Ying-Ji
authors.initials: YJ
authors.lastname: Li
authors.forename: Masao
authors.initials: M
authors.lastname: Katsumata
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood*; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood*; D007564:Japan / Q000453:epidemiology; D024821:Metabolic Syndrome / Q000097:blood*; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D014280:Triglycerides; D055105:Waist Circumference; D014931:Women, Working
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D008076:Cholesterol, HDL; D007328:Insulin; D014280:Triglycerides