title: The Use of Calcium Channel Blockers in the Treatment of Coronary Spasm and Atrioventricular Block.
abstract: Calcium channel blockers have been used in the treatment of coronary artery spasm for many years. However, there is insufficient knowledge about their application to treat atrioventricular block caused by coronary spasm. Clinical data of five patients who were diagnosed with coronary spasm caused by atrioventricular block and treated with calcium channel blockers were retrospectively assessed. The patients had varying degrees of atrioventricular block (confirmed by Holter ECG) and myocardial ischemia-like ST-T changes. Two patients were II type I AVB, two patients II type II AVB, and the remaining one patient was III AVB. All patients were all diagnosed with right coronary artery spasm by coronary angiography. The patients were treated with calcium channel blockers. No patient reported recurrence of chest pain or chest discomfort. On Holter ECG monitoring, no significant myocardial ischemia or atrioventricular block was seen. In conclusion, calcium channel blockers are effective and safe in the treatment of atrioventricular block caused by coronary spasm.
authors.affiliation: Suizhou Central Hospital, Affiliated Hospital of Hubei University of Medicine, Wuhan, Hubei, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Gao
authors.affiliation: Suizhou Central Hospital, Affiliated Hospital of Hubei University of Medicine, Wuhan, Hubei, China.
authors.forename: Zhenjian
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Suizhou Central Hospital, Affiliated Hospital of Hubei University of Medicine, Wuhan, Hubei, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Qian
authors.affiliation: Suizhou Central Hospital, Affiliated Hospital of Hubei University of Medicine, Wuhan, Hubei, China.
authors.forename: Chuanbin
authors.initials: C
authors.lastname: Cao
authors.affiliation: Suizhou Central Hospital, Affiliated Hospital of Hubei University of Medicine, Wuhan, Hubei, China.
authors.forename: Xianping
authors.initials: X
authors.lastname: Hua
authors.affiliation: Suizhou Central Hospital, Affiliated Hospital of Hubei University of Medicine, Wuhan, Hubei, China.
authors.forename: Mengting
authors.initials: M
authors.lastname: Chu
authors.affiliation: Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Road, Wuhan, 430030, Hubei, China.
authors.forename: Xingwei
authors.initials: X
authors.lastname: He
authors.affiliation: Department of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Road, Wuhan, 430030, Hubei, China. zenghs@tjh.tjmu.edu.cn.
authors.forename: Hesong
authors.initials: H
authors.lastname: Zeng
mesh_terms: D054537:Atrioventricular Block / Q000000981:diagnostic imaging / Q000188:drug therapy*; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002317:Cardiovascular Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000000981:diagnostic imaging / Q000188:drug therapy*; D004110:Diltiazem / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D002121:Calcium Channel Blockers; D002317:Cardiovascular Agents; D004110:Diltiazem
keywords: Atrioventricular block; Calcium channel blockers; Coronary spasm; Treatment