title: [Complications of graft infection after endovascular aortic aneurysm repair].
abstract: OBJECTIVE
  The endovascular approach to aortic aneurysm repair is widely spreading as an alternative to open repair. However infectious complications may be devastating. We described the experiences with infected aortic endografts and reviewed treatment and outcomes.
  
  
  METHODS
  Eight patients were treated due to infected aortic endografts between June 2008 and March 2014. Seven males and 1 female with median age of 66 years( range, 38-84years) had 5 infected thoracic endovascular aortic repairs (EVARs) [5/142:3.5%] and 3 endovascular aortic repairs (EVARs)[3/387:0.8%]. Median time from repair to presentation was 12 months (range, 2-27 months). As the factors associated with infection, hemodialysis due to chronic kidney disease in 1, surgical treatment for the huge atheroma in 1, dental treatment in 2, treatment for infected aneurysm in 1, urinary tract infection after surgery for prostate in 1, aortoenteric fistula after TEVAR in 2 were considered.
  
  
  RESULTS
  Five patients were treated with endograft explantation. The surgical mortality was 40% (2/5), during a follow-up, one more patient died with intracranial hemorrhage. The remaining 3 patients who were considered too high risk to remove the infectious endografts were treated conservatively with antibiotics. In 2 of them 1 died of respiratory failure, and multiple organ failure in 1.
  
  
  CONCLUSIONS
  Infection of the endograft is a rare but devastating complication after endovascular repair of aortic aneurysms. Surgical removal of the infected prosthesis is accompanied with higher mortality, but antibiotics therapy cannot eradicate or cure the infection. In all cases, the factors associated with infection were calculated, and degenerative or infectious thrombi around the endovascular stent grafts were noted. Therefore, we consider that prophylactic antibiotic treatment may be necessary to prevent the bacteremia in the case of other surgical therapy or dental treatment.
authors.affiliation: Department of Cardiovascular Surgery, Tokushima Prefectural Central Hospital, Tokushima, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Kano
authors.forename: Eiki
authors.initials: E
authors.lastname: Fujimoto
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Wariishi
authors.forename: Fumio
authors.initials: F
authors.lastname: Chikugo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019072:Antibiotic Prophylaxis; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D016470:Bacteremia / Q000209:etiology / Q000517:prevention & control; D057510:Endovascular Procedures / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants / Q000009:adverse effects* / Q000382:microbiology*; D011475:Prosthesis Failure / Q000009:adverse effects*; D016459:Prosthesis-Related Infections / Q000209:etiology* / Q000517:prevention & control / Q000601:surgery; D015607:Stents / Q000009:adverse effects* / Q000382:microbiology*