title: Implanted electrodes for multi-month EEG.
abstract: An implanted electroencephalogram (EEG) recorder would help diagnose infrequent seizure-like events. A proof-of-concept study quantified the electrical characteristics of the electrodes planned for the proposed recorder. The electrodes were implanted in an ovine model for eight weeks. Electrode impedance was less than 800 Ohms throughout the study. A frequency-domain determination of sedation performed similarly for surface versus implanted electrodes throughout the study. The time-domain correlation between an implanted electrode and a surface electrode was almost as high as between two surface electrodes (0.86 versus 0.92). EEG-certified clinicians judged that the implanted electrode quality was adequate to excellent and that the implanted electrodes provided the same clinical information as surface electrodes except for a noticeable amplitude difference. No significant issues were found that would stop development of the EEG recorder.
authors.forename: Thomas
authors.initials: T
authors.lastname: Jochum
authors.forename: Susannah
authors.initials: S
authors.lastname: Engdahl
authors.forename: Brad J
authors.initials: BJ
authors.lastname: Kolls
authors.forename: Patrick
authors.initials: P
authors.lastname: Wolf
mesh_terms: D000818:Animals; D001931:Brain Mapping / Q000295:instrumentation / Q000379:methods*; D017097:Electric Impedance; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D005260:Female; D023421:Models, Animal; D012756:Sheep; D012815:Signal Processing, Computer-Assisted