title: Susceptibility of Glycopeptide-Resistant Enterococci to Linezolid, Quinupristin/dalfopristin, Tigecycline and Daptomycin in a Tertiary Greek Hospital.
abstract: We investigated the antibiotic susceptibility of glycopeptide-resistant enterococci (GRE). Seventy consecutive GRE were tested. Sixty-two isolates were identified as Enterococcus faecium (88.6%), and 8 (11.4%) as Enterococcus faecalis. All strains were susceptible to linezolid and daptomycin, while 17.1% (12/70) and 11.4% (8/70) were resistant to quinupristin/dalfopristin (QD) and tigecycline, respectively. All E. faecalis isolates were resistant to QD, while 4 of 62 (6.5%) E. faecium isolates were resistant to QD. All E. faecalis isolates were susceptible to tigecycline, while 14.5% (9/62) E. faecium isolates were resistant. Continued surveillance of GRE antibiotic susceptibilities is important for combating these multi-resistant nosocomial pathogens.
authors.affiliation: Department of Clinical Microbiology, Parasitology, Zoonoses and Geographical Medicine, University Hospital of Heraklion, Crete, Greece.
authors.forename: Sofia
authors.initials: S
authors.lastname: Maraki
authors.affiliation: Department of Internal Medicine, Infectious Diseases Unit, University of Crete Medical School, Heraklion, Crete, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Samonis
authors.affiliation: Department of Internal Medicine, Infectious Diseases Unit, University of Crete Medical School, Heraklion, Crete, Greece.
authors.forename: Dimitra
authors.initials: D
authors.lastname: Dimopoulou
authors.affiliation: Department of Pediatrics, Democritus University of Thrace Faculty of Medicine and University General District Hospital of Alexandroupolis, Thrace, Greece.
authors.forename: Elpis
authors.initials: E
authors.lastname: Mantadakis
keywords: Daptomycin; Glycopeptide-resistant enterococci; Linezolid; Quinupristin/dalfopristin; Teicoplanin; Tigecycline