title: Recent progress on countercurrent chromatography modeling.
abstract: As countercurrent chromatography is becoming an established method in chromatography for many kinds of products, it is becoming increasingly important to model the process and to be able to predict the peaks for a given process. The CCC industries are looking for rapid methods to analyze the processes of countercurrent chromatography and select suitable solvent system. In this paper, recent progress is reviewed in the development and demonstration of several types of models of countercurrent chromatography. Literature lists a number of countercurrent chromatography (CCC) models that can predict the retention time and to a certain extent the peak width of a solute eluting from a CCC column, such as cell model, CCD model, CSTRs model, probabilistic model, temperature dependence plate model, physical models, etc.
authors.affiliation: State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Chaoyang District, Beijing 100029, China. Tel &
authors.forename: Fengkang
authors.initials: F
authors.lastname: Wang
authors.affiliation: Laboratory of Bioseparation Technology, Biochemistry and Biophysics Center, NHLBI, National Institutes of Health, Bldg. 10, Room 8N230, Bethesda, MD 20892, USA.
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Ito
authors.affiliation: State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Chaoyang District, Beijing 100029, China. Tel &
authors.forename: Yun
authors.initials: Y
authors.lastname: Wei
keywords: Countercurrent chromatography; Separation process; model