title: Bilateral Dentate Gyrus Structural Alterations in a Cat Associated With Hippocampal Sclerosis and Intraventricular Meningioma.
abstract: A 13-year-old cat had a history of seizures for 3 years that resembled temporal lobe epilepsy. Histologic examination of the brain revealed bilateral hippocampal alterations, including hypergyration and broadening of the dentate gyrus associated with hippocampal sclerosis and an intraventricular meningioma near the hippocampal region. The findings in the dentate gyrus were interpreted as a congenital malformation; however, it could not be ruled out that the alterations were induced by the seizures. Similar changes of the dentate gyrus have not been previously described in cats.
authors.affiliation: Institute of Pathology and Forensic Veterinary Medicine, Department for Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Klang
authors.affiliation: Institute of Pathology and Forensic Veterinary Medicine, Department for Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria denise.thaller@vetmeduni.ac.at.
authors.forename: D
authors.initials: D
authors.lastname: Thaller
authors.affiliation: Institute of Pathology and Forensic Veterinary Medicine, Department for Pathobiology, University of Veterinary Medicine Vienna, Vienna, Austria.
authors.forename: P
authors.initials: P
authors.lastname: Schmidt
authors.affiliation: Institute of Neurology, Medical University of Vienna, Vienna, Austria.
authors.forename: G G
authors.initials: GG
authors.lastname: Kovacs
authors.affiliation: National Institute of Neuroscience, Budapest, Hungary.
authors.forename: P
authors.initials: P
authors.lastname: Halasz
authors.affiliation: University Clinic for Small Animals, Department for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Pakozdy
mesh_terms: D000818:Animals; D002415:Cats; D018891:Dentate Gyrus / Q000473:pathology; D006624:Hippocampus / Q000473:pathology; D008577:Meningeal Neoplasms / Q000473:pathology / Q000662:veterinary*; D008579:Meningioma / Q000473:pathology / Q000662:veterinary*; D012598:Sclerosis / Q000473:pathology / Q000662:veterinary*; D012640:Seizures / Q000662:veterinary
keywords: cat; dentate gyrus; hippocampal sclerosis; hippocampus; histopathology; malformation; meningioma; temporal lobe epilepsy