title: Measurement of anti-Mullerian hormone: performances of a new ultrasensitive immunoassay.
abstract: The measurement of anti-Mullerian hormone (AMH) is relevant for the evaluation of primary ovarian insufficiency, success of assisted reproductive therapies, and also to support the diagnosis of polycystic ovary syndrome. Our study demonstrated excellent analytical performances for the Ansh Laboratories AMH immunoassay and an overall good agreement with the AMH Gen II assay. Nevertheless, the two AMH immunoassays are not using the same couple of antibodies and therefore not commutable and the definition of specific reference values and cut-point remains necessary.
authors.affiliation: Pôle de recherche en Endocrinologie, Diabète et Nutrition, Institut de Recherche Expérimentale et Clinique, Cliniques Universitaires St-Luc, Université Catholique de Louvain, Brussels, Belgium; Department of Laboratory Medicine, Cliniques Universitaires St-Luc, Université Catholique de Louvain, Brussels, Belgium. Electronic address: damien.gruson@uclouvain.be.
authors.forename: Damien
authors.initials: D
authors.lastname: Gruson
authors.affiliation: Department of Laboratory Diagnosis, University Clinical Centre Maribor, Maribor, Slovenia.
authors.forename: Evgenija
authors.initials: E
authors.lastname: Homsak
mesh_terms: D054304:Anti-Mullerian Hormone / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay / Q000592:standards; D005260:Female; D006801:Humans; D057230:Limit of Detection; D065851:Ovarian Reserve; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000175:diagnosis*
chemical_list: D054304:Anti-Mullerian Hormone
keywords: AMH; Infertility; Ovarian reserve; Polycystic ovaries; TGF-β