title: Primary renal large cell neuroendocrine carcinoma in a young man.
abstract: Neuroendocrine tumours are usually located in the gastrointestinal or respiratory tract. A 23-year-old man was evaluated for loss of weight and a palpable left loin mass. CECT showed a large heterogeneously enhancing mass with calcification arising from the left kidney. He underwent an open radical nephrectomy. Histopathological examination revealed a large cell neuroendocrine carcinoma (LCNEC). LCNEC of the kidney is extremely rare and portends poor prognosis. It is usually a histopathological surprise and requires immunohistochemistry for confirmation.
authors.affiliation: Senior Registrar, Department of Urology, CMC , Vellore, Tamil Nadu, India .
authors.forename: Cornerstone
authors.initials: C
authors.lastname: Wann
authors.affiliation: Associate Professor, Department of Urology, CMC , Vellore, Tamil Nadu, India .
authors.forename: Nirmal Thampi
authors.initials: NT
authors.lastname: John
authors.affiliation: Professor, Department of Pathology, CMC , Vellore, Tamil Nadu, India .
authors.forename: Ramani Manoj
authors.initials: RM
authors.lastname: Kumar
keywords: Cancer; Kidney; Neuroendocrine