title: [The use of tizanidine in combined treatment of arm poststroke spasticity].
abstract: OBJECTIVE
  Muscle tone disorders, including poststroke spasticity, is a frequent cause of disability. We studied the efficacy and safety of tizalud (tizanidine) in patients with arm poststroke spasticity.
  
  
  METHODS
  Forty-four patients were treated with tizalud and botulotoxin A in different doses in complex with rehabilitation measures or without them.
  
  
  CONCLUSIONS
  The marked improvement (the decrease in spasticity, increase in muscle power and pain syndrome intensity) was noted in patients treated with the combination of tizalud and botulotoxin A.
authors.forename: D R
authors.initials: DR
authors.lastname: Khasanova
authors.forename: N V
authors.initials: NV
authors.lastname: Agafonova
authors.forename: G Kh
authors.initials: GKh
authors.lastname: Starostina
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use*; D001132:Arm; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D003000:Clonidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000209:etiology; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D020521:Stroke / Q000150:complications; D000071939:Stroke Rehabilitation
chemical_list: D000927:Anticonvulsants; D009465:Neuromuscular Agents; C023754:tizanidine; D019274:Botulinum Toxins, Type A; D003000:Clonidine