title: A novel Microchannel Electrode Array: towards bioelectronic medical interfacing of small peripheral nerves.
abstract: Bioelectronic medicine is an emerging field that relies on electrical signals to modulate complex neuronal circuits, particularly in the peripheral nervous system, as an alternative to drug-enabled therapeutics. Small autonomic nerves are one of the targets in this field, however, interfacing peripheral nerves smaller than 300 μm remains a challenge. Here we report the development of a Microchannel Electrode Array (DCEA) capable of interfacing nerve fascicles as small as 50-300μm. The current μCEA records and stimulates from 28 channels and is designed for easy implantation and removal, bearing promise to enable neural interfacing in BM.
authors.forename: Y T
authors.initials: YT
authors.lastname: Kim
authors.forename: A
authors.initials: A
authors.lastname: Kanneganti
authors.forename: S
authors.initials: S
authors.lastname: Fatemi
authors.forename: C
authors.initials: C
authors.lastname: Nothnagle
authors.forename: M
authors.initials: M
authors.lastname: Wijesundara
authors.forename: M I
authors.initials: MI
authors.lastname: Romero-Ortega
mesh_terms: D000818:Animals; D004567:Electrodes, Implanted; D008839:Microelectrodes; D058117:Neural Prostheses; D010525:Peripheral Nerves / Q000502:physiology / Q000601:surgery; D011474:Prosthesis Design; D051381:Rats; D017207:Rats, Sprague-Dawley