title: Toward the development of smart and low cost point-of-care biosensors based on screen printed electrodes.
abstract: Screen printing technology provides a cheap and easy means to fabricate disposable electrochemical devices in bulk quantities which are used for rapid, low-cost, on-site, real-time and recurrent industrial, pharmaceutical or environmental analyses. Recent developments in micro-fabrication and nano-characterization made it possible to screen print reproducible feature on materials including plastics, ceramics and metals. The processed features forms screen-printed disposable biochip (SPDB) upon the application of suitable bio-chemical recognition receptors following appropriate methods. Adequacy of biological and non-biological materials is the key to successful biochip development. We can further improve recognition ability of SPDBs by adopting new screen printed electrode (SPE) configurations. This review covers screen-printing theory with special emphasis on the technical impacts of SPE architectures, surface treatments, operational stability and signal sensitivity. The application of SPE in different areas has also been summarized. The article aims to highlight the state-of-the-art of SPDB at the laboratory scale to enable us in envisaging the deployment of emerging SPDB technology on the commercial scale.
authors.affiliation: a Biosensors and Biotechnology Laboratory, Chemical Science Programme, Faculty of Science , Universiti Brunei Darussalam , Gadong , Negara Brunei Darussalam .
authors.forename: Minhaz Uddin
authors.initials: MU
authors.lastname: Ahmed
authors.affiliation: b Institute of Forestry and Environmental Sciences, University of Chittagong , Chittagong , Bangladesh .
authors.forename: Mohammad Mosharraf
authors.initials: MM
authors.lastname: Hossain
authors.affiliation: c Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology (MIT) , Cambridge , MA , USA .
authors.forename: Mohammadali
authors.initials: M
authors.lastname: Safavieh
authors.affiliation: a Biosensors and Biotechnology Laboratory, Chemical Science Programme, Faculty of Science , Universiti Brunei Darussalam , Gadong , Negara Brunei Darussalam .
authors.forename: Yen Lu
authors.initials: YL
authors.lastname: Wong
authors.affiliation: a Biosensors and Biotechnology Laboratory, Chemical Science Programme, Faculty of Science , Universiti Brunei Darussalam , Gadong , Negara Brunei Darussalam .
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Abd Rahman
authors.affiliation: d Center of Biomedical Engineering, Cranfield University , Bedfordshire , UK , and.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Zourob
authors.affiliation: e Nanobioengineering Laboratory, Department of Applied Physics , Graduate School of Engineering, Osaka University , Osaka , Japan.
authors.forename: Eiichi
authors.initials: E
authors.lastname: Tamiya
mesh_terms: D015374:Biosensing Techniques; D001709:Biotechnology / Q000295:instrumentation / Q000379:methods / Q000639:trends; D004566:Electrodes; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods / Q000639:trends; D011327:Printing
keywords: Biochips; biosensors; electrochemical detection; recognition receptors; screen printing