title: Eligibility for renal transplantation: a Moroccan interregional survey.
abstract: In the treatment of end-stage renal disease, kidney transplantation (KT) is the best and most cost-effective alternative with regard to both prognosis and quality of life. To identify the proportion and the characteristics of kidney transplant candidates who can be considered eligible, a total of 2066 hemodialysis patients were investigated as part of the ARTEMIS (Attitude toward Renal Transplantation and Eligibility among dialysis patients in a Moroccan Interregional Survey) study. We investigated all patients receiving hemodialysis in the 39 centers of four Moroccan departments. The mean age was 52.9 years and the mean duration of hemodialysis was 55.3 months. Fifty-eight percent of our patients were considered eligible for KT; 18.2% had an absolute contraindication and 23.8% had one or more relative contraindications. When compared with eligible patients (n = 1200) in the univariate analysis, those ineligible were significantly older (61 years vs. 51, P < 0.0001), had no residual diuresis (59.8% vs. 49.1%, P < 0.0001), were more often diabetic (25.1% vs. 11.9%, P < 0.0001) and hypertensive (54.5% vs. 45.8%, P < 0.0001), and their median dialysis duration was longer (61 months vs. 51, P < 0.0001). In the multivariate models, eligibility remained associated with young age, less term of dialysis and residual diuresis. Adequate control of cardiovascular risk factors before dialysis and early referral for transplantation might help to improve eligibility of the renal transplant candidates.
authors.affiliation: Department of Nephrology, Hassan II University Hospital, Fez, Morocco.
authors.forename: Nadia
authors.initials: N
authors.lastname: Kabbali
authors.forename: Souad
authors.initials: S
authors.lastname: Mikou
authors.forename: Ghita
authors.initials: G
authors.lastname: El Bardai
authors.forename: Adil
authors.initials: A
authors.lastname: Najdi
authors.forename: Meriem
authors.initials: M
authors.lastname: Ezziani
authors.forename: Fatima Zahra
authors.initials: FZ
authors.lastname: Batta
authors.forename: Nada Tazi
authors.initials: NT
authors.lastname: El Pardiya
authors.forename: Chadia
authors.initials: C
authors.lastname: El Fadil
authors.forename: Aniss
authors.initials: A
authors.lastname: El Hassani
authors.forename: Mohamed
authors.initials: M
authors.lastname: Arrayhani
authors.forename: Tarik Sqalli
authors.initials: TS
authors.lastname: Houssaini
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D000075202:Contraindications; D003928:Diabetic Nephropathies / Q000150:complications*; D004231:Diuresis; D004608:Eligibility Determination; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000150:complications; D007676:Kidney Failure, Chronic / Q000209:etiology* / Q000601:surgery* / Q000628:therapy; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009018:Morocco; D009393:Nephritis / Q000150:complications; D018579:Patient Selection; D006435:Renal Dialysis; D013997:Time Factors; D055815:Young Adult