title: Oscillations in human orbitofrontal cortex during even chance gambling.
abstract: Evaluating value and risk as well as comparing expected and actual outcomes is the crux of decision making and reinforcement based learning. In this study, we record from stereotactic electroencephalograph depth electrodes in a human subject in numerous areas in the brain. We focus on the lateral and medial orbitofrontal cortex while they perform a gambling task involving betting on a high card. Preliminary time-frequency analysis shows modulations in the 5-15 Hz band that is well synced to the different events of the task. These oscillations increase in both high betting scenarios as well as in losing scenarios though their effects cannot be decoupled. However, the activity between lateral and medial orbitofrontal cortex is a lot more homogenous than previously seen. Additionally, the timing of some of these oscillations occurs before even a response in the visual cortex. This evidence hints that these areas encode priors that influence our decision in future statistically ambiguous scenarios.
authors.forename: Kevin
authors.initials: K
authors.lastname: Kahn
authors.forename: Matthew S D
authors.initials: MS
authors.lastname: Kerr
authors.forename: Hyun-Joo
authors.initials: HJ
authors.lastname: Park
authors.forename: Susan
authors.initials: S
authors.lastname: Thompson
authors.forename: Juan
authors.initials: J
authors.lastname: Bulacio
authors.forename: Jorge
authors.initials: J
authors.lastname: Gonzalez-Martinez
authors.forename: Sridevi V
authors.initials: SV
authors.lastname: Sarma
authors.forename: John
authors.initials: J
authors.lastname: Gale
mesh_terms: D001519:Behavior; D001931:Brain Mapping; D002540:Cerebral Cortex; D003657:Decision Making / Q000502:physiology*; D004567:Electrodes, Implanted; D004569:Electroencephalography; D005260:Female; D005625:Frontal Lobe; D005715:Gambling / Q000503:physiopathology*; D005717:Games, Experimental; D006801:Humans; D007858:Learning / Q000502:physiology; D008297:Male; D017397:Prefrontal Cortex / Q000502:physiology*; D012054:Reinforcement, Psychology; D018570:Risk Assessment; D012815:Signal Processing, Computer-Assisted