title: Pulsatile operation of the BiVACOR TAH - Motor design, control and hemodynamics.
abstract: Although there is limited consensus about the strict requirement to deliver pulsatile perfusion to the human circulatory system, speed modulation of rotary blood pumps is an approach that may capture the benefits of both positive displacement and continuous flow blood pumps. In the current stage of development of the BiVACOR Total Artificial Heart emphasis is placed on providing pulsatile outflow from the pump. Multiple pulsatile speed profiles have been applied in preliminary in-vivo operation in order to assess the capability of the TAH to recreate a physiologic pulse. This paper provides an overview about recent research towards pulsatile BiVACOR operation with special emphasis on motor and control requirements and developments.
authors.forename: Matthias
authors.initials: M
authors.lastname: Kleinheyer
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Timms
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Greatrex
authors.forename: Toru
authors.initials: T
authors.lastname: Masuzawa
authors.forename: O Howard
authors.initials: OH
authors.lastname: Frazier
authors.forename: William E
authors.initials: WE
authors.lastname: Cohn
mesh_terms: D000818:Animals; D001243:Assisted Circulation / Q000379:methods; D002417:Cattle; D006354:Heart, Artificial; D006439:Hemodynamics; D006801:Humans; D008297:Male; D011474:Prosthesis Design; D011673:Pulsatile Flow / Q000502:physiology