title: An in Vitro Evaluation of Remineralization Potential of Novamin(®) on Artificial Enamel Sub-Surface Lesions Around Orthodontic Brackets Using Energy Dispersive X-Ray Analysis (EDX).
abstract: OBJECTIVE
  To evaluate and compare the Ca/P ratio of enamel samples around the orthodontic brackets for time periods of 0, 2 and 10 days in two groups (control group and study group).
  
  
  METHODS
  Forty extracted teeth were randomly divided into control group and study group. All samples were demineralized and incubated in artificial saliva at 37°C for a period of 10 days after demineralization. During this phase the enamel samples in the study group were treated with remineralizing paste (NuproNusolution containing Novamin®-Dentsply) for 10 days. At the end of the incubation period, Ca/P ratios were analyzed for both the groupsby EDX analysis. Data obtained was subjected to statistical analysis using student t-test for paired samples and Student t- test for individual samples (p ≤ 0.05).
  
  
  RESULTS
  It was found that the mean Ca/P ratio was significantly lower for the control group as compared to the study group (p-value < 0.05) after 10 d of incubation.
  
  
  CONCLUSIONS
  Novamin(®) containing remineralization toothpaste showed significant remineralizing potential in inhibition of artificial enamel sub-surface lesion around bracket after 10 days of remineralization phase. EDX element analysis was found to be an efficient method to quantify the changes in mineral content of a sample during in vitro caries studies.
authors.affiliation: Senior Lecturer, Department of Orthodontics & Dentofacial Orthopaedics, Kalinga Institute of Dental Sciences, KIIT University Bhubaneswar, Odisha, India .
authors.forename: Pritam
authors.initials: P
authors.lastname: Mohanty
authors.affiliation: Professor, Department of Orthodontics & Dentofacial Orthopaedics, Faculty of Dental Sciences, Sri Ramachandra University , Porur, Chennai, Tamil Nadu, India .
authors.forename: Sridevi
authors.initials: S
authors.lastname: Padmanabhan
authors.affiliation: Professor & Head, Department of Orthodontics & Dentofacial Orthopaedics, Faculty of Dental Sciences, Sri Ramachandra University , Porur, Chennai, Tamil Nadu, India .
authors.forename: Arun B
authors.initials: AB
authors.lastname: Chitharanjan
keywords: Demineralization; Orthodontics; White spot lesions