title: Determination of halosulfuron-methyl herbicide in sugarcane juice and tomato by capillary electrophoresis-tandem mass spectrometry.
abstract: A capillary electrophoresis-tandem mass spectrometry (CE-MS/MS) method for the determination of halosulfuron-methyl (HSU) residue in samples of sugarcane juice and tomato is introduced and validated. The samples were submitted to a QuEChERS extraction procedure followed by electrophoretic separation in NH4HCO3 electrolyte (adjusted to pH 8.5) and detection by electrospray-tandem mass spectrometry. The total HSU migration took place in less than 3.5 min, and the detection was accomplished by monitoring three fragmentation processes of this anion: m/z 435-182, 139, and 83. The R(2) values for concentrations up to 100 ppb (μg kg(-1)) were, respectively, 0.992, 0.992, and 0.978. Recovery values for samples spiked at three concentration levels (10, 20 and 50 ppb) were in the range of 96-104% with standard deviation not greater than 5.0%. The limit of detection for HSU in sugarcane juice and tomato was 2 ppb for both samples.
authors.affiliation: Agilent Technologies, Alameda Araguaia, 1142, CEP 06455-000 Barueri, SP, Brazil. Electronic address: daniela_daniel@agilent.com.
authors.forename: Daniela
authors.initials: D
authors.lastname: Daniel
authors.affiliation: Departamento de Química Fundamental - Instituto de Química - Universidade de São Paulo, Av. Prof. Lineu Prestes, 748, CEP 05508-000 São Paulo - SP, Brazil. Electronic address: vagnerbs@iq.usp.br.
authors.forename: Vagner Bezerra
authors.initials: VB
authors.lastname: dos Santos
authors.affiliation: Departamento de Química Fundamental - Instituto de Química - Universidade de São Paulo, Av. Prof. Lineu Prestes, 748, CEP 05508-000 São Paulo - SP, Brazil. Electronic address: denistadeu@gmail.com.
authors.forename: Denis Tadeu Rajh
authors.initials: DT
authors.lastname: Vidal
authors.affiliation: Departamento de Química Fundamental - Instituto de Química - Universidade de São Paulo, Av. Prof. Lineu Prestes, 748, CEP 05508-000 São Paulo - SP, Brazil. Electronic address: claudemi@iq.usp.br.
authors.forename: Claudimir Lucio
authors.initials: CL
authors.lastname: do Lago
mesh_terms: D019075:Electrophoresis, Capillary / Q000379:methods; D006540:Herbicides / Q000032:analysis / Q000737:chemistry*; D018551:Solanum lycopersicum / Q000737:chemistry*; D031786:Saccharum / Q000737:chemistry*; D013453:Sulfonylurea Compounds / Q000737:chemistry* / Q000378:metabolism*; D053719:Tandem Mass Spectrometry / Q000379:methods
chemical_list: D006540:Herbicides; D013453:Sulfonylurea Compounds; C532033:halosulfuron methyl
keywords: Capillary electrophoresis; Halosulfuron-methyl; Halosulfuron-methyl (PubChem CID: 91763); QuEChERS; Sugarcane; Tandem mass spectrometry; Tomato