title: Orofacial granulomatosis as a presenting feature of Crohn's disease.
abstract: An 11-year-old girl was referred to oral medicine with persistent facial swelling. She was diagnosed with orofacial granulomatosis (OFG) and was treated conservatively for 7 years, with no evidence of systemic illness. Aged 17 she re-presented with a flare up of her OFG, watery diarrhoea and fluctuating febrile episodes. Inflammatory markers were raised and an MR enterogram revealed terminal ileal Crohn's disease. This case highlights that OFG may precede the onset of intestinal Crohn's disease.
authors.affiliation: Department of Gastroenterology, Singleton Hospital, Swansea, UK.
authors.forename: Victoria Caroline Elizabeth
authors.initials: VC
authors.lastname: Jennings
authors.affiliation: Department of Gastroenterology, Singleton Hospital, Swansea, UK.
authors.forename: Lisa
authors.initials: L
authors.lastname: Williams
authors.affiliation: Department of Gastroenterology, Singleton Hospital, Swansea, UK.
authors.forename: Sophie
authors.initials: S
authors.lastname: Henson
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D003424:Crohn Disease / Q000175:diagnosis* / Q000276:immunology; D005247:Feeding Behavior; D005260:Female; D051261:Granulomatosis, Orofacial / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D009067:Mouthwashes / Q000627:therapeutic use*; D011239:Prednisolone / Q000627:therapeutic use*; D012008:Recurrence; D016896:Treatment Outcome
chemical_list: D009067:Mouthwashes; D011239:Prednisolone