title: Isoleojaponin, a new Halimane diterpene isolated from Leonurus japonicus.
abstract: Leojaponin (2), a labdane diterpene, was isolated from the EtOH extract of the herb of Leonurus japonicus together with a new halimane diterpene named isoleojaponin (1). Isoleojaponin has a new diterpene skeleton with a unique cross-conjugated α,β-unsaturated ketone system, Their structures were elucidated by physical and spectroscopic analysis, and the relative configuration of the chiral C-9 carbon was determined by a computational method, and analysis of its possible biogenesis pathways.
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. hkwu@aynu.edu.cn.
authors.forename: Hankui
authors.initials: H
authors.lastname: Wu
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. wssn2006@163.com.
authors.forename: Sensheng
authors.initials: S
authors.lastname: Wang
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. xzytyyl1314@hotmail.com.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Xu
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. sssaynu@163.com.
authors.forename: Shanshan
authors.initials: S
authors.lastname: Sun
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. liuaynu@163.com.
authors.forename: Haijuan
authors.initials: H
authors.lastname: Liu
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. wangaynu@163.com.
authors.forename: Jinjin
authors.initials: J
authors.lastname: Wang
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. yanaynu@163.com.
authors.forename: Yan
authors.initials: Y
authors.lastname: E
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. lvaynu@163.com.
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Lv
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. dongaynu@163.com.
authors.forename: Xuelin
authors.initials: X
authors.lastname: Dong
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. lgorgchem@126.com.
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. lpzhang70@163.com.
authors.forename: Liping
authors.initials: L
authors.lastname: Zhang
authors.affiliation: College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China. yfshi@aliyun.com.
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Shi
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D031332:Leonurus / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D021241:Spectrometry, Mass, Electrospray Ionization; D013056:Spectrophotometry, Ultraviolet
chemical_list: D004224:Diterpenes