title: Chemical constituents from Piper wallichii.
abstract: Fifteen known compounds including four triterpenoids (1-4), one sterol (5), one diketopiperazine alkaloid (6) and nine phenolics (7-15) were isolated from the stems of Piper wallichii. Their structures were elucidated by means of spectroscopic analysis, and acidic hydrolysis in case of the 2-oxo-3β,19α,23-trihydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester (1). The structure of compound 1 was fully assigned by 1D and 2D NMR experiments for the first time. All isolates were tested for their antibacterial, antifungal, anti-inflammatory and antiplatelet aggregation bioactivities.
authors.affiliation: a State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , People's Republic of China.
authors.forename: Yan-Ni
authors.initials: YN
authors.lastname: Shi
authors.forename: Lian
authors.initials: L
authors.lastname: Yang
authors.forename: Jin-Hua
authors.initials: JH
authors.lastname: Zhao
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Shi
authors.forename: Yan
authors.initials: Y
authors.lastname: Qu
authors.forename: Hong-Tao
authors.initials: HT
authors.lastname: Zhu
authors.forename: Dong
authors.initials: D
authors.lastname: Wang
authors.forename: Chong-Ren
authors.initials: CR
authors.lastname: Yang
authors.forename: Xing-Cong
authors.initials: XC
authors.lastname: Li
authors.forename: Min
authors.initials: M
authors.lastname: Xu
authors.forename: Ying-Jun
authors.initials: YJ
authors.lastname: Zhang
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D000818:Animals; D001419:Bacteria / Q000187:drug effects; D001792:Blood Platelets / Q000187:drug effects; D002460:Cell Line / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D051379:Mice; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D010840:Phytosterols / Q000737:chemistry*; D031701:Piper / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry; D011817:Rabbits; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D010636:Phenols; D010840:Phytosterols; D014315:Triterpenes
keywords: Piper wallichii; miscellaneous constituents; triterpenoid glycoside