title: [Association between serum uric acid and fasting plasma glucose in middle and elderly Chinese].
abstract: OBJECTIVE
  To examine the association of fasting plasma glucose (FPG) and serum uric acid (SUA) in middle and elderly Chinese.
  
  
  METHODS
  10 413 Guangzhou residents aged ≥50 were included in the present study. Information on personal history, physical examination and biochemical parameters were collected. Subjects were grouped by the FPG level, association between FPG and SUA. Levels of hyperuricemia (HUA) were evaluated.
  
  
  RESULTS
  The SUA levels and the incidence of HUA showed trends of increasing, with the increasing FPG levels in women, with statistically significant differences seen among all the FPG groups (P value for trend<0.05). While the statistical differences of SUA levels and the incidence rates of HUA among diabetes group (DM group) and impaired fasting glucose (IFG) groups were non-significant (P > 0.05) but it was higher than normal FPG group in men (P < 0.05). Logistic regression models were built between various FPG groups and HUA. After adjusting for age, smoking status, drinking status, physical activity, hypertension, body mass index and the levels of triglyceride and creatin. When compared to the normal FPG group, the risk of women suffering from HUA increased by 40% (95%CI:1.19-1.64) under the FPG in the range of 6.1-6.9 mmol/L. Compared to those non-diabetic individuals, the risk of diabetic patients suffering from HUA also increased by 44% (95% CI:1.15-1.79) in women. However, the risk of suffering from HUA did not relate to the increase of FPG in men.
  
  
  CONCLUSIONS
  The SUA level and the incidence of HUA tended to increase along with the increasing levels of FPG in middle and elderly Chinese women and the increase of FPG might also increase the risk of HUA, but not in men.
authors.affiliation: No. 12 Affiliated Hospital of Guangzhou Medical University, Guangzhou 510620, China.
authors.forename: Yongjie
authors.initials: Y
authors.lastname: Yu
authors.affiliation: No. 12 Affiliated Hospital of Guangzhou Medical University, Guangzhou 510620, China. Email: jcqianggz@163.com.
authors.forename: Chaoqiang
authors.initials: C
authors.lastname: Jiang
authors.affiliation: No. 12 Affiliated Hospital of Guangzhou Medical University, Guangzhou 510620, China.
authors.forename: Yali
authors.initials: Y
authors.lastname: Jin
authors.affiliation: Department of Community Medicine, School of Public Health, University of Hong Kong.
authors.forename: Lin
authors.initials: L
authors.lastname: Xu
authors.affiliation: No. 12 Affiliated Hospital of Guangzhou Medical University, Guangzhou 510620, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.affiliation: No. 12 Affiliated Hospital of Guangzhou Medical University, Guangzhou 510620, China.
authors.forename: Weisen
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Public Health and Epidemiology, University of Birmingham, UK.
authors.forename: Karkeung
authors.initials: K
authors.lastname: Cheng
authors.affiliation: Department of Community Medicine, School of Public Health, University of Hong Kong.
authors.forename: Taihing
authors.initials: T
authors.lastname: Lam
mesh_terms: D000368:Aged; D044466:Asian People; D001786:Blood Glucose; D002681:China / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000453:epidemiology; D005215:Fasting / Q000097:blood*; D005260:Female; D006801:Humans; D033461:Hyperuricemia / Q000453:epidemiology*; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State / Q000453:epidemiology; D012307:Risk Factors; D017678:Sex Distribution; D014527:Uric Acid / Q000097:blood*
chemical_list: D001786:Blood Glucose; D014527:Uric Acid