title: Postpandemic Influenza A/H1N1pdm09 is still Causing Severe Perinatal Complications.
abstract: Although influenza A/H1N1pdm09 is not causing a pandemic anymore, we recently observed two critically ill pregnant women infected by this virus. We present these cases to illustrate the possible severe complications of an - at that moment - seasonal influenza in pregnancy. We discuss the epidemiological differences between the pandemic and post pandemic phase and try to explain the high virulence of influenza A/H1N1pdm09 -infections in pregnancy by discussing insights in immunology during pregnancy. We conclude that although influenza A/H1N1pdm09 is in the post pandemic phase, infection by this influenza virus still needs to be considered in pregnant women with progressive respiratory dysfunction.
authors.affiliation: Erasmus MC, University Medical Centre Rotterdam, Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, University Medical Centre Rotterdam.
authors.forename: Hein
authors.initials: H
authors.lastname: Bogers
authors.affiliation: Erasmus MC, University Medical Centre Rotterdam, Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, University Medical Centre Rotterdam.
authors.forename: Dominique
authors.initials: D
authors.lastname: Bos
authors.affiliation: Erasmus MC, University Medical Centre Rotterdam, Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, University Medical Centre Rotterdam.
authors.forename: Sam
authors.initials: S
authors.lastname: Schoenmakers
authors.affiliation: Erasmus MC, University Medical Centre Rotterdam, Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, University Medical Centre Rotterdam.
authors.forename: Johannes J
authors.initials: JJ
authors.lastname: Duvekot