title: Predictors of success of different treatment modalities for management of ectopic pregnancy.
abstract: Aim. The purpose of this study was to investigate factors affecting the success of different treatment modalities for the management of ectopic pregnancy (EP). Methods. One hundred and ninety-seven patients with EP, were included in the study. Patients were treated with either intramuscular methotrexate (Mtx) or surgical treatment. Results. Mtx was applied in 97 (49.2%) patients. In 67 patients (69.1%), a single dose of Mtx and in 30 patients (30.9%) a multiple dose of Mtx was applied. Forty-seven (70.14%) patients were successfully treated with a single-dose Mtx. In the multiple-dose group, the success rate was 70% (21/30 patients). The difference between the success rates was not statistically significant. When the initial serum βhCG value was <1000 mIU/mL, the overall success rate of Mtx treatment was determined to be 86.11%; however, the rate decreased to 42.3% when the βhCG value was >3000 mIU/mL. On the other hand, if the EP mass diameter was <25 mm, the success rate was 89.28% and decreased to 52.63% when it was ≥25 mm. Conclusion. The results of the study showed that single-dose treatment with Mtx could be as successful as multiple doses. Overall success of Mtx treatment depended on initial βhCG value and EP mass diameter.
authors.affiliation: Department of Gynecology and Obstetrics, School of Medicine, Adnan Menderes University, 09010 Aydın, Turkey.
authors.forename: Sümeyra Nergiz
authors.initials: SN
authors.lastname: Avcioğlu
authors.affiliation: Department of Gynecology and Obstetrics, School of Medicine, Adnan Menderes University, 09010 Aydın, Turkey.
authors.forename: Sündüz Özlem
authors.initials: SÖ
authors.lastname: Altinkaya
authors.affiliation: Department of Gynecology and Obstetrics, School of Medicine, Muğla Sıtkı Koçman University, 48000 Muğla, Turkey.
authors.forename: Mert
authors.initials: M
authors.lastname: Küçük
authors.affiliation: Department of Gynecology and Obstetrics, School of Medicine, Adnan Menderes University, 09010 Aydın, Turkey.
authors.forename: Selda
authors.identifier: 0000-0002-2744-5363
authors.initials: S
authors.lastname: Demircan Sezer
authors.affiliation: Department of Gynecology and Obstetrics, School of Medicine, Adnan Menderes University, 09010 Aydın, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Yüksel