title: Cohort study of a simple 'Step-Up' regimen with the Asthma Control Test.
abstract: This prospective cohort study investigates whether simple guideline-based asthma management using a 'Step-Up' regimen with the Asthma Control Test score improves asthma control in patients with inadequately controlled asthma in primary care. Seventy out of ninety-three (75%) participants achieved a score of > 19 (good control), and the mean increase in Asthma Control Test score was 6.0 (95% confidence interval: 5.3-6.8), P < 0.001. The improvement was independent of baseline inhaled corticosteroid use.
authors.affiliation: School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.
authors.forename: Shaun
authors.initials: S
authors.lastname: Holt
authors.forename: Mitesh
authors.initials: M
authors.lastname: Patel
authors.forename: Barney
authors.initials: B
authors.lastname: Montgomery
authors.forename: Mark
authors.initials: M
authors.lastname: Weatherall
authors.forename: Richard
authors.initials: R
authors.lastname: Beasley
mesh_terms: D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage*; D000328:Adult; D000368:Aged; D001249:Asthma / Q000175:diagnosis / Q000628:therapy*; D004359:Drug Therapy, Combination; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
chemical_list: D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists
keywords: asthma; clinical trials; inhaled corticosteroid; long-acting beta-agonist; patient management