title: Radiation recall dermatitis induced by tamoxifen during adjuvant breast cancer treatment.
abstract: Tamoxifen and radiotherapy are used in breast cancer treatment worldwide. Radiation recall dermatitis (RRD), induced by tamoxifen, has been rarely reported. Herein, we report a RRD case induced by tamoxifen. A 47-year-old woman had a right quadrantectomy and an axillary lymph node dissection due to breast cancer. The tumor was staged pT2N0; it was hormone receptor positive, and human epidermal growth factor receptor 2 negative. The patient received adjuvant chemotherapy followed by tamoxifen and radiotherapy. After 22 months of tamoxifen, the patient developed a localized heating sensation, tenderness, edema, and redness at the irradiated area of the right breast. The symptoms improved within 1 week without treatment. Three weeks later, however, the patient developed similar symptoms in the same area of the breast. She continued tamoxifen before and during dermatitis, and symptoms resolved within 1 week.
authors.affiliation: Department of Internal Medicine, Jeju National University Hospital, Jeju, Korea.
authors.forename: Jiyoung
authors.initials: J
authors.lastname: Rhee
authors.affiliation: Department of Radiation Oncology, Jeju National University Hospital, Jeju, Korea.
authors.forename: Gwi Eon
authors.initials: GE
authors.lastname: Kim
authors.affiliation: Department of General Surgery, Jeju National University Hospital, Jeju, Korea.
authors.forename: Chang Hyun
authors.initials: CH
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Jeju National University Hospital, Jeju, Korea.
authors.forename: Jung-Mi
authors.initials: JM
authors.lastname: Kwon
authors.affiliation: Department of Internal Medicine, Jeju National University Hospital, Jeju, Korea.
authors.forename: Sang-Hoon
authors.initials: SH
authors.lastname: Han
authors.affiliation: Department of Radiation Oncology, Jeju National University Hospital, Jeju, Korea.
authors.forename: Young Suk
authors.initials: YS
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Jeju National University Hospital, Jeju, Korea.
authors.forename: Woo-Kun
authors.initials: WK
authors.lastname: Kim
keywords: Radiation recall dermatitis; Tamoxifen; Treatment