title: Hypercoagulability and venous thromboembolism in burn patients.
abstract: To our knowledge, this is the first comprehensive review on the subject of venous thromboembolism (VTE) and hypercoagulability in burn patients. Specific changes in coagulability are reviewed using data from thromboelastography and other techniques. Disseminated intravascular coagulation in burn patients is discussed. The incidence and risk factors associated with VTE in burn patients are then examined, followed by the use of low-molecular-weight heparin thromboprophylaxis and monitoring techniques using antifactor Xa levels. The need for large, prospective trials in burn patients is highlighted, especially in the areas of VTE incidence and safe, effective thromboprophylaxis.
authors.affiliation: Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Meizoso
authors.affiliation: Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
authors.forename: Juliet J
authors.initials: JJ
authors.lastname: Ray
authors.affiliation: Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
authors.forename: Casey J
authors.initials: CJ
authors.lastname: Allen
authors.affiliation: Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Van Haren
authors.affiliation: Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Ruiz
authors.affiliation: Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
authors.forename: Nicholas
authors.initials: N
authors.lastname: Namias
authors.affiliation: Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
authors.forename: Carl I
authors.initials: CI
authors.lastname: Schulman
authors.affiliation: Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
authors.forename: Louis R
authors.initials: LR
authors.lastname: Pizano
authors.affiliation: Divisions of Trauma, Surgical Critical Care, and Burns at the Ryder Trauma Center, The DeWitt Daughtry Family Department of Surgery, University of Miami Leonard M. Miller School of Medicine, Miami, Florida.
authors.forename: Kenneth G
authors.initials: KG
authors.lastname: Proctor
mesh_terms: D002056:Burns / Q000097:blood*; D006801:Humans; D012307:Risk Factors; D013916:Thrombelastography / Q000379:methods; D019851:Thrombophilia / Q000097:blood* / Q000209:etiology*; D054556:Venous Thromboembolism / Q000097:blood* / Q000209:etiology*