title: Repeated sugammadex usage in a patient with multiple sclerosis: a case report.
abstract: A 42-year-old woman been suffering from multiple sclerosis for 2 years received an emergency laparotomy because of acute pancreatitis. Anesthesia was induced with propofol and fentanil and maintained with nitrous oxide and sevoflurane. Rocuronium was used for tracheal intubation and muscle relaxation. Train of four ratio was monitored for tracing muscle relaxation. Three days later the patient was operated again due to abdominal cavity infection and followed up with "open abdomen strategy" receiving general anesthesia with 3 days intervals. In all of the six general anesthesia procedures in 18 days the patient was successfully reversed with sugammadex.
authors.affiliation: Anesthesiology Department, Bagcilar Egitim ve Arastirma Hospital, 34200, Bagcilar/Istanbul, Turkey. sitkinadir@yahoo.com.
authors.forename: Nadir
authors.initials: N
authors.lastname: Sinikoglu
authors.affiliation: Anesthesiology Department, Bagcilar Egitim ve Arastirma Hospital, 34200, Bagcilar/Istanbul, Turkey.
authors.forename: Tolga
authors.initials: T
authors.lastname: Totoz
authors.affiliation: Anesthesiology Department, Bagcilar Egitim ve Arastirma Hospital, 34200, Bagcilar/Istanbul, Turkey.
authors.forename: Funda
authors.initials: F
authors.lastname: Gumus
authors.affiliation: General Surgery Department, Bagcilar Egitim ve Arastirma Hospital, 34200, Bagcilar/Istanbul, Turkey.
authors.forename: Onur
authors.initials: O
authors.lastname: Karagulle
mesh_terms: D000328:Adult; D000732:Androstanols / Q000008:administration & dosage* / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009103:Multiple Sclerosis / Q000188:drug therapy*; D019148:Neuromuscular Blockade / Q000009:adverse effects / Q000379:methods; D061886:Neuromuscular Monitoring / Q000379:methods; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage / Q000037:antagonists & inhibitors; D010243:Paralysis / Q000139:chemically induced* / Q000517:prevention & control*; D011292:Premedication / Q000379:methods; D000077123:Rocuronium; D000077122:Sugammadex; D016896:Treatment Outcome; D047408:gamma-Cyclodextrins / Q000008:administration & dosage*
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D000077123:Rocuronium
keywords: Multiple sclerosis; Sugammadex