title: Energy and Macronutrient Intake in the Midwest Exercise Trial 2 (MET-2).
abstract: OBJECTIVE
  This study aimed to examine the effect of exercise training over 10 months at two levels of energy expenditure on energy and macronutrient intake in a sample of previously sedentary, overweight/obese young adults.
  
  
  METHODS
  We conducted a 10-month trial in 141 young adults who were randomized to either supervised exercise 5 d·wk(-1) at 400 and 600 kcal per session or nonexercise control. Participants were instructed to maintain their usual ad libitum diet. Energy/macronutrient intake was assessed at baseline and 3.5, 7, and 10 months over 7-d periods of ad libitum eating in a university cafeteria using digital photography. Foods consumed outside the cafeteria were assessed using multiple-pass recalls.
  
  
  RESULTS
  There were no significant between-group differences in absolute energy intake at baseline or at any other time point in the total sample or in men. In women, absolute energy intake was significantly greater in the 600-kcal-per-session group versus controls at both 3.5 and 7 months. There were no significant between-group differences in relative energy intake (kcal·kg·d(-1)) at any time point in the total sample, in men or women. There were no significant within- or between-group differences of change in absolute or relative energy intake in any of the three study groups in the total sample or in men or women. No clinically relevant changes in macronutrient intake were observed.
  
  
  CONCLUSIONS
  Aerobic exercise training does not significantly alter energy or macronutrient intake in overweight and obese young adults. The possibility of a threshold level beyond which increased exercise energy expenditure fails to produce a more negative energy balance and potential sex differences in the energy intake response to increased levels of exercise are potentially important.
authors.affiliation: 1Cardiovascular Research Institute, Division of Internal Medicine, University of Kansas Medical Center, Kansas City, KS; 2Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS; 3Institute for Measurement, Methodology, Analysis, and Policy, Texas Tech University, Lubbock, TX; and 4Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City, KS.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Washburn
authors.forename: Jeff J
authors.initials: JJ
authors.lastname: Honas
authors.forename: Lauren T
authors.initials: LT
authors.lastname: Ptomey
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Mayo
authors.forename: Jaehoon
authors.initials: J
authors.lastname: Lee
authors.forename: Debra K
authors.initials: DK
authors.lastname: Sullivan
authors.forename: Kathleen
authors.initials: K
authors.lastname: Lambourne
authors.forename: Erik A
authors.initials: EA
authors.lastname: Willis
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Donnelly
mesh_terms: D000293:Adolescent; D000328:Adult; D002149:Energy Intake; D004734:Energy Metabolism; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000503:physiopathology / Q000628:therapy; D050177:Overweight / Q000503:physiopathology* / Q000628:therapy*; D010806:Physical Education and Training / Q000379:methods; D057185:Sedentary Behavior; D015431:Weight Loss; D055815:Young Adult