title: On the characterization of single-event related brain activity from functional Magnetic Resonance Imaging (fMRI) measurements.
abstract: We propose an efficient numerical technique for calibrating the mathematical model that describes the single-event related brain response when fMRI measurements are given. This method employs a regularized Newton technique in conjunction with a Kalman filtering procedure. We have applied this method to estimate the biophysiological parameters of the Balloon model that describes the hemodynamic brain responses. Illustrative results obtained with both synthetic and real fMRI measurements are presented.
authors.forename: Nafiseh
authors.initials: N
authors.lastname: Khoram
authors.forename: Chadia
authors.initials: C
authors.lastname: Zayane
authors.forename: Taous-Meriem
authors.initials: TM
authors.lastname: Laleg-Kirati
authors.forename: Rabia
authors.initials: R
authors.lastname: Djellouli
mesh_terms: D000465:Algorithms; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010100:Oxygen / Q000097:blood; D012815:Signal Processing, Computer-Assisted
chemical_list: D010100:Oxygen