title: Osteopetrosis: radiological & radionuclide imaging.
abstract: Osteopetrosis is a rare inherited bone disease where bones harden and become abnormally dense. While the diagnosis is clinical, it also greatly relies on appearance of the skeleton radiographically. X-ray, radionuclide bone scintigraphy and magnetic resonance imaging have been reported to identify characteristics of osteopetrosis. We present an interesting case of a 59-year-old man with a history of bilateral hip fractures. He underwent (99m)Tc-methylene diphosphonate whole body scan supplemented with single-photon emission computed tomography/computed tomography of spine, which showed increased uptake in the humeri, tibiae and femora, which were in keeping with osteopetrosis.
authors.affiliation: School of Medicine, King's College London, UK.
authors.forename: Cherry
authors.initials: C
authors.lastname: Sit
authors.affiliation: Department of Nuclear Medicine, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
authors.forename: Kanhaiyalal
authors.initials: K
authors.lastname: Agrawal
authors.affiliation: Department of Nuclear Medicine, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
authors.forename: Ignac
authors.initials: I
authors.lastname: Fogelman
authors.affiliation: Department of Nuclear Medicine, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
authors.forename: Gopinath
authors.initials: G
authors.lastname: Gnanasegaran
keywords: Dual-energy X-ray absorptiometry; osteopetrosis; single-photon emission computed tomography/computed tomography