title: [Blood transfusion - the value of Research and Development programs].
abstract: Transfusion is a mixed discipline which includes the production of blood components, applied biology aiming in particular at establishing the highest compatibility for immunological characteristics between blood components to be delivered to patients and recipients, and, finally translational medicine to evaluate the effectiveness of the transfused products and to proactively avoid hazards, at least those that are preventible and can be anticipated. The whole chain takes place with the concern of continuous improvement of quality and safety. These two principles (quality/safety) have been and still are concerns of constant progress applicable to all the transfusion chain steps; they benefit from programs of Research and Development (R&D). Fundamental research, basic but also applied and clinical research, accompanies, in a constantly joint manner, scientific and medical progresses by providing new solutions to dampen the current problems and to prepare the future.
authors.affiliation: Université de Lyon/Saint-Étienne, 42023 Saint-Étienne cedex 02, France; Institut national de la transfusion sanguine, 75015 Paris, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Garraud
authors.affiliation: Établissement français du sang, 1, boulevard Alexander-Fleming, 25000 Besançon, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Morel
authors.affiliation: Laboratoire TransDiag, Établissement français du sang Pyrénées-Méditerranée, 34184 Montpellier cedex 4, France; Établissement français du sang, 20, avenue du Stade-de-France, 93218 La Plaine Saint-Denis, France.
authors.forename: Joliette
authors.initials: J
authors.lastname: Coste
authors.affiliation: Établissement français du sang, 20, avenue du Stade-de-France, 93218 La Plaine Saint-Denis, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Tiberghien
authors.affiliation: Laboratoire TransDiag, Établissement français du sang Pyrénées-Méditerranée, 34184 Montpellier cedex 4, France. Electronic address: chantal.fournier@efs.sante.fr.
authors.forename: Chantal
authors.initials: C
authors.lastname: Fournier-Wirth
mesh_terms: D001782:Blood Donors / Q000600:supply & distribution; D058731:Blood Safety / Q000379:methods*; D001800:Blood Specimen Collection / Q000009:adverse effects / Q000592:standards; D001803:Blood Transfusion / Q000379:methods*; D006801:Humans; D036103:Nanotechnology / Q000379:methods; D017096:Prion Diseases / Q000097:blood / Q000175:diagnosis; D011328:Prions / Q000097:blood / Q000302:isolation & purification; D012106:Research; D065227:Transfusion Reaction
chemical_list: D011328:Prions