title: Identification of novel interactors of human telomeric G-quadruplex DNA.
abstract: A chemoproteomic-driven approach was used to investigate the interaction network between human telomeric G-quadruplex DNA and nuclear proteins. We identified novel G-quadruplex binding partners, able to recognize these DNA structures at chromosome ends, suggesting a possible, and so far unknown, role of these proteins in telomere functions.
authors.affiliation: Department of Pharmacy, University of Naples "Federico II", Via D. Montesano 49, 80131 Napoli, Italy. bruno.pagano@unina.it.
authors.forename: Bruno
authors.initials: B
authors.lastname: Pagano
authors.forename: Luigi
authors.initials: L
authors.lastname: Margarucci
authors.forename: Pasquale
authors.initials: P
authors.lastname: Zizza
authors.forename: Jussara
authors.initials: J
authors.lastname: Amato
authors.forename: Nunzia
authors.initials: N
authors.lastname: Iaccarino
authors.forename: Chiara
authors.initials: C
authors.lastname: Cassiano
authors.forename: Erica
authors.initials: E
authors.lastname: Salvati
authors.forename: Ettore
authors.initials: E
authors.lastname: Novellino
authors.forename: Annamaria
authors.initials: A
authors.lastname: Biroccio
authors.forename: Agostino
authors.initials: A
authors.lastname: Casapullo
authors.forename: Antonio
authors.initials: A
authors.lastname: Randazzo
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D054856:G-Quadruplexes; D045325:HCT116 Cells; D006801:Humans; D040901:Proteomics; D016615:Telomere / Q000235:genetics*
chemical_list: D004268:DNA-Binding Proteins; D004247:DNA