title: Factors associated with willingness to participate in clinical trials: a nationwide survey study.
abstract: BACKGROUND
  This study was conducted to investigate awareness of clinical trials (CTs) including perceptions of favorable feelings about, necessity for, and safety of CTs, the ultimate beneficiary of CTs and the factors associated with willingness to participate in CTs among the general population in South Korea.
  
  
  METHODS
  A cross sectional survey study was conducted in a randomly selected national sample of 1,515 Korean.
  
  
  RESULTS
  Perception toward CTs was measured using a scale from 0 (strongly disagree) to 10 (strongly agree). Respondents readily understood the necessity for CTs (M = 7.27, SD = 2.15); had moderately favorable feelings (M = 5.32, SD = 2.31) toward CTs and felt that these CTs were moderately safe (M =  .71, SD = 1.90). Twenty-five percent of the respondents answered that they would be willing to participate in a CT in the future. Perception of the ultimate benefits of CTs, awareness, favorable feelings, safety, and necessity regarding CTs were identified as significant predictors of willingness to participate in CTs.
  
  
  CONCLUSIONS
  An awareness of CTs and the perceptions toward CTs were associated with general public willingness to participate in a CT. Findings from this study can be used in planning outreach and recruitment strategies, and to understand the predictors of CT participation.
authors.affiliation: Nursing Policy and Research Institute, Biobehavioral Research Center, College of Nursing, Yonsei University, Seoul, Republic of Korea. shchu@yuhs.ac.
authors.forename: Sang Hui
authors.initials: SH
authors.lastname: Chu
authors.affiliation: Division of Nursing, College of Medicine, Hallym University, Chuncheon, Gangwon-do, Republic of Korea. ejerkim@hallym.ac.kr.
authors.forename: Eun Jung
authors.initials: EJ
authors.lastname: Kim
authors.affiliation: College of Nursing, Research Institute of Nursing Science, Chonbuk National University, 567 Baekje-daero, deokjin-gu, Jeonju-si, Jeollabuk-do, 561-756, Republic of Korea. awesomeprof@jbnu.ac.kr.
authors.forename: Seok Hee
authors.initials: SH
authors.lastname: Jeong
authors.affiliation: Cardiovascular Center, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea. hori07@yuhs.ac.
authors.forename: Geu Lee
authors.initials: GL
authors.lastname: Park
mesh_terms: D000328:Adult; D001294:Attitude to Health; D002986:Clinical Trials as Topic / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D010358:Patient Participation / Q000523:psychology*; D018579:Patient Selection; D056910:Republic of Korea / Q000453:epidemiology; D012959:Socioeconomic Factors