title: Corporoplasty using buccal mucosa graft in Peyronie disease: is it a first choice?
abstract: OBJECTIVE
  To assesses the surgical and functional efficacy of corporoplasty with buccal mucosa graft, patients and partner's satisfaction, and the low cost of this operation. Biocompatible tissues are frequently used during corporoplasty, but they are expensive and often do not match the thickness and elasticity of the tunica albuginea, leading to fibrosis and scar retraction. Buccal mucosa graft is not usually emphasized in many review articles and clinical studies are limited.
  
  
  METHODS
  Thirty-two patients with stable disease and normal erections were included in this retrospective study. All patients underwent corporoplasty with plaque incision and buccal mucosa graft. Preoperative International Index of Erectile Function (IIEF) questionnaire and penile duplex ultrasonographies with measurement of curvature were conducted. At 6 and 12 months postoperatively, patients answered the IIEF and the Patient Global Impression of Improvement questionnaires. Patient and partner satisfaction were recorded at all subsequent visits.
  
  
  RESULTS
  Thirty-two patients underwent corporoplasty between 2006 and 2013, and no major complications developed in any patient. After 1 year, curvature relapse was present in 1 patient (3.5%), and 1 patient had slight erectile dysfunction. IIEF values had significantly improved 1 year after surgery (P = .031). Patient satisfaction was 85% on the Patient Global Impression of Improvement questionnaire. Twenty-five of 28 partners were satisfied (90%). Data analysis confirmed the stability of the IIEF score in 16 patients after 2 years (mean IIEF score, 21.3).
  
  
  CONCLUSIONS
  Corporoplasty with buccal mucosa graft is easy to perform and represents a good treatment choice for most forms of Peyronie disease with curvature preventing penetration and sexual intercourse.
authors.affiliation: Department of Urology and Andrology, S.M. Misericordia Hospital, University of Perugia, Perugia, Italy. Electronic address: zucchi.urologia@gmail.com.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Zucchi
authors.affiliation: Department of Urology "Degli Infermi" Hospital, Biella, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Silvani
authors.affiliation: Department of Urology, Surgical Sciences and Biotechnologies, "La Sapienza" University, Rome, Italy.
authors.forename: Antonio Luigi
authors.initials: AL
authors.lastname: Pastore
authors.affiliation: Department of Urology, Hospital ASUR Marche Area Vasta 3, Macerata, Italy.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Fioretti
authors.affiliation: Department of Urology, Hospital ASUR Marche Area Vasta 3, Macerata, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Fabiani
authors.affiliation: Department of Urology and Andrology, S.M. Misericordia Hospital, University of Perugia, Perugia, Italy.
authors.forename: Tommaso
authors.initials: T
authors.lastname: Villirillo
authors.affiliation: Department of Urology and Andrology, S.M. Misericordia Hospital, University of Perugia, Perugia, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Costantini
mesh_terms: D000328:Adult; D000368:Aged; D003365:Costs and Cost Analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000637:transplantation*; D017060:Patient Satisfaction; D010411:Penile Induration / Q000601:surgery*; D010413:Penis / Q000601:surgery*; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D013521:Urologic Surgical Procedures, Male / Q000191:economics / Q000379:methods