title: Microelectrode Arrays and the Use of PEG-Functionalized Diblock Copolymer Coatings.
abstract: PEG-modified diblock copolymer surfaces have been examined for their compatibility with microelectrode array based analytical methods. The use of PEG-modified polymer surfaces on the arrays was initially problematic because the redox couples used in the experiments were adsorbed by the polymer. This led the current measured by cyclic voltammetry for the redox couple to be unstable and increase with time. However, two key findings allow the experiments to be successful. First, after multiple cyclic voltammograms the current associated with the redox couple does stabilize so that a good baseline current can be established. Second, the rate at which the current stabilizes is consistent every time a particular coated array is used. Hence, multiple analytical experiments can be conducted on an array coated with a PEG-modified diblock copolymer and the data obtained is comparable as long as the data for each experiment is collected at a consistent time point.
authors.affiliation: Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA; E-Mails: suppal@wustl.edu (S.U.); mgraaf@wustl.edu (M.D.G.).
authors.forename: Sakshi
authors.initials: S
authors.lastname: Uppal
authors.affiliation: Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA; E-Mails: suppal@wustl.edu (S.U.); mgraaf@wustl.edu (M.D.G.).
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Graaf
authors.affiliation: Department of Chemistry, Washington University in St. Louis, St. Louis, MO 63130, USA; E-Mails: suppal@wustl.edu (S.U.); mgraaf@wustl.edu (M.D.G.).
authors.forename: Kevin D
authors.initials: KD
authors.lastname: Moeller
keywords: PEG; cyclic voltammetry; ferrocene carboxylic acid; microelectrode arrays