title: Prospective long-term study of patency and outcomes of 505 arteriovenous fistulas in patients with chronic renal failure: Authors experience and review of literature.
abstract: BACKGROUND
  This study describes our experience of arteriovenous fistula (AVF) creation as vascular access for haemodialysis.
  
  
  METHODS
  This study has been carried out in our hospital from January 2004 to December 2012. A total of 505 AVFs were created in 443 patients. Maximum follow-up was 8 years, and minimum was 6 months.
  
  
  RESULTS
  In this study of 505 cases of AVFs, primary patency rates by Kaplan - Meier analysis showed 78.81% patency of fistulas at the end of 1 year and patency dropped to 14.81% at the end of 5 years. Our primary failure rate was 21.2%. Basilic vein was used in 26.35% cases, cephalic vein in 63.5%, and antecubital vein in 9.75% cases. On table, bruit was present in 459 (90.9%) and thrill in 451 (89.3%) cases. During dialysis, flow rate >250 ml/min was obtained in 150 (29.9%) cases. In complications, 2 (0.4%) patients developed distal oedema, 33 (6.5%) developed steal phenomenon.
  
  
  CONCLUSIONS
  Presence of on table thrill and bruit are indicators of successful AVF. If vein diameter is <2 mm, chances of AVF failure are high. Flow rates in patients with vein diam. >2 mm were significantly higher as compared with patients with vein diam. <2 mm (P < 0.001). Flow rates are higher in non-diabetic patients as compared to diabetic patients (P < 0.001). Average blood urea and serum creatinine values are significantly lesser in patients undergoing dialysis through successful fistulas as compared to patients with failed fistulas. Correspondingly, incidence of deaths is significantly lesser in patients with successful fistulas. During proximal side-to-side fistula between antecubital/basilic vein and brachial artery, dilating of the first valve toward wrist helps to develop distal veins in the forearm by retrograde flow. This technique avoids requirement of superficialization of basilic vein in the arm.
authors.affiliation: Department of Plastic Surgery, Nephrology Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
authors.forename: Parag
authors.initials: P
authors.lastname: Sahasrabudhe
authors.affiliation: Department of Nephrology Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
authors.forename: Tushar
authors.initials: T
authors.lastname: Dighe
authors.affiliation: Department of Plastic Surgery, Sassoon Hospitals, Pune, Maharashtra, India.
authors.forename: Nikhil
authors.initials: N
authors.lastname: Panse
authors.affiliation: Department of Plastic Surgery, Nephrology Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
authors.forename: Shraddha
authors.initials: S
authors.lastname: Deshpande
authors.affiliation: Department of Plastic Surgery, Nephrology Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
authors.forename: Amit
authors.initials: A
authors.lastname: Jadhav
authors.affiliation: Department of Plastic Surgery, Nephrology Deenanath Mangeshkar Hospital, Pune, Maharashtra, India.
authors.forename: Sheetal
authors.initials: S
authors.lastname: Londhe
keywords: Arteriovenous fistula; chronic kidney disease; haemodialysis; vascular access