title: You may have worked on more adaptive designs than you think.
authors.affiliation: From the Department of Biostatistics, University of Iowa, Iowa City. christopher-coffey@uiowa.edu.
authors.forename: Christopher S
authors.initials: CS
authors.lastname: Coffey
mesh_terms: D002986:Clinical Trials as Topic / Q000592:standards* / Q000639:trends; D006801:Humans; D012107:Research Design / Q000592:standards* / Q000639:trends; D020521:Stroke / Q000628:therapy*
keywords: adaptive designs; clinical trials; clinical trials data monitoring committee; early termination of clinical trials; group sequential designs