title: Hemophagocytic lymphohistiocytosis in 2 patients with underlying IFN-γ receptor deficiency.
authors.affiliation: Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institute, Karolinska University Hospital Solna, Stockholm, Sweden; Clinical Genetics Unit, Department of Molecular Medicine and Surgery, and Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Bianca
authors.initials: B
authors.lastname: Tesi
authors.affiliation: Department of Pediatric Hematology Oncology, Anna Meyer Children's University Hospital, Florence, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Sieni
authors.affiliation: Primary Immunodeficiencies Unit, Hospital Dona Estefania, Pediatric University Hospital, and CEDOC, Chronic Diseases Research Center, NOVA Medical School, Lisbon, Portugal.
authors.forename: Conceição
authors.initials: C
authors.lastname: Neves
authors.affiliation: Department of Pediatric Immunology, University of Florence, and Anna Meyer Children's University Hospital, Jeffrey Modell Center for Primary Immunodeficiencies, Florence, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Romano
authors.affiliation: Department of Pediatric Hematology Oncology, Anna Meyer Children's University Hospital, Florence, Italy.
authors.forename: Valentina
authors.initials: V
authors.lastname: Cetica
authors.affiliation: Primary Immunodeficiencies Unit, Hospital Dona Estefania, Pediatric University Hospital, and CEDOC, Chronic Diseases Research Center, NOVA Medical School, Lisbon, Portugal.
authors.forename: Ana Isabel
authors.initials: AI
authors.lastname: Cordeiro
authors.affiliation: Centre for Infectious Medicine, Department of Medicine, Karolinska Institute, Karolinska University Hospital Huddinge, Stockholm, Sweden.
authors.forename: Samuel
authors.initials: S
authors.lastname: Chiang
authors.affiliation: Centre for Infectious Medicine, Department of Medicine, Karolinska Institute, Karolinska University Hospital Huddinge, Stockholm, Sweden.
authors.forename: Heinrich
authors.initials: H
authors.lastname: Schlums
authors.affiliation: Department of Pediatric Infectious Diseases, Anna Meyer Children's University Hospital, Florence, Italy.
authors.forename: Luisa
authors.initials: L
authors.lastname: Galli
authors.affiliation: Department of Pediatric Intensive Care, Anna Meyer Children's University Hospital, Florence, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Avenali
authors.affiliation: Department of Pediatric Hematology Oncology, Anna Meyer Children's University Hospital, Florence, Italy.
authors.forename: Annalisa
authors.initials: A
authors.lastname: Tondo
authors.affiliation: Department of Pediatric Immunology, University of Florence, and Anna Meyer Children's University Hospital, Jeffrey Modell Center for Primary Immunodeficiencies, Florence, Italy.
authors.forename: Clementina
authors.initials: C
authors.lastname: Canessa
authors.affiliation: Childhood Cancer Research Unit, Department of Women's and Children's Health, Karolinska Institute, Karolinska University Hospital Solna, Stockholm, Sweden.
authors.forename: Jan-Inge
authors.initials: JI
authors.lastname: Henter
authors.affiliation: Clinical Genetics Unit, Department of Molecular Medicine and Surgery, and Center for Molecular Medicine, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Magnus
authors.initials: M
authors.lastname: Nordenskjöld
authors.affiliation: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
authors.forename: Amy P
authors.initials: AP
authors.lastname: Hsu
authors.affiliation: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Holland
authors.affiliation: Primary Immunodeficiencies Unit, Hospital Dona Estefania, Pediatric University Hospital, and CEDOC, Chronic Diseases Research Center, NOVA Medical School, Lisbon, Portugal.
authors.forename: João F
authors.initials: JF
authors.lastname: Neves
authors.affiliation: Department of Pediatric Immunology, University of Florence, and Anna Meyer Children's University Hospital, Jeffrey Modell Center for Primary Immunodeficiencies, Florence, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Azzari
authors.affiliation: Centre for Infectious Medicine, Department of Medicine, Karolinska Institute, Karolinska University Hospital Huddinge, Stockholm, Sweden; Broegelmann Research Laboratory, Department of Clinical Sciences, University of Bergen, Norway. Electronic address: Yenan.Bryceson@ki.se.
authors.forename: Yenan T
authors.initials: YT
authors.lastname: Bryceson
mesh_terms: D001483:Base Sequence; D002675:Child, Preschool; D003586:Cytomegalovirus Infections / Q000150:complications / Q000276:immunology* / Q000382:microbiology / Q000821:virology; D020031:Epstein-Barr Virus Infections / Q000150:complications / Q000276:immunology* / Q000382:microbiology / Q000821:virology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D007694:Killer Cells, Natural / Q000276:immunology / Q000473:pathology; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications / Q000276:immunology* / Q000382:microbiology / Q000821:virology; D008969:Molecular Sequence Data; D009154:Mutation; D009504:Neutrophils / Q000276:immunology / Q000473:pathology; D017471:Receptors, Interferon / Q000172:deficiency* / Q000235:genetics / Q000276:immunology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology / Q000473:pathology; D014376:Tuberculosis / Q000150:complications / Q000276:immunology* / Q000382:microbiology / Q000821:virology; D014777:Virus Diseases / Q000150:complications / Q000276:immunology* / Q000382:microbiology / Q000821:virology
chemical_list: C086185:IFNGR2 protein, human; D017471:Receptors, Interferon