title: Some dendritic cells active inside tumors.
abstract: Macrophages within tumors quell immune attacks on the cancer cells, but a new study shows that tumors also contain a small number of CD103+ dendritic cells that activate antitumor CD8+ T cells. The dendritic cells help shrink tumors in mouse models, and their presence might serve as a prognostic biomarker-and improve the odds of survival for patients.
mesh_terms: D000818:Animals; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology; D002450:Cell Communication / Q000276:immunology; D003713:Dendritic Cells / Q000276:immunology* / Q000473:pathology; D006801:Humans; D008264:Macrophages / Q000276:immunology; D051379:Mice; D009369:Neoplasms / Q000276:immunology* / Q000473:pathology / Q000628:therapy