title: Transfusion-related acute lung injury following coronary artery bypass graft surgery.
abstract: Blood transfusion is sometimes a necessary procedure during or following coronary artery bypass graft (CABG) surgery. However, transfusion-related acute lung injury (TRALI)/possible TRALI is a rare and fatal complication and characterized by acute hypoxemia and non-cardiogenic pulmonary edema that occurs within 6 hours following a transfusion. Anti-leukocyte antibodies or, possibly, other bioactive substances cause inflammation and capillary endothelial destruction in susceptible recipients' lungs. Prompt diagnosis and mechanical ventilatory support are important. A successful treatment of two male patients following CABG surgery, compatible with TRALI/possible TRALI, is presented here.
authors.affiliation: Cardiovascular Surgery Department, Kafkas University Medical Faculty, Kars, Turkey mctbtr@hotmail.com.
authors.forename: M
authors.initials: M
authors.lastname: Bitargil
authors.affiliation: Cardiovascular Surgery Department, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Arslan
authors.affiliation: Cardiovascular Surgery Department, Kafkas University Medical Faculty, Kars, Turkey.
authors.forename: H S
authors.initials: HS
authors.lastname: Başbuğ
authors.affiliation: Cardiovascular Surgery Department, Kafkas University Medical Faculty, Kars, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Göçer
authors.affiliation: Cardiovascular Surgery Department, Kafkas University Medical Faculty, Kars, Turkey.
authors.forename: Y
authors.initials: Y
authors.lastname: Günerhan
authors.affiliation: Cardiovascular Surgery Department, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey.
authors.forename: Y Y
authors.initials: YY
authors.lastname: Bekov
mesh_terms: D055371:Acute Lung Injury / Q000209:etiology* / Q000628:therapy; D000328:Adult; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000628:therapy*; D065227:Transfusion Reaction
keywords: acute lung injury; blood transfusion; cardiac surgery; complication; coronary artery bypass