title: Supramolecular intracellular delivery of an anionic porphyrin by octaarginine-conjugated per-O-methyl-β-cyclodextrin.
abstract: A convenient and efficient method for intracellular delivery of a water-soluble anionic porphyrin has been developed by utilizing its supramolecular interaction with per-O-methyl-β-cyclodextrin bearing an octaarginine chain as a cell-penetrating peptide.
authors.affiliation: Department of Molecular Chemistry and Biochemistry, Faculty of Science and Engineering, Doshisha University, Kyotanabe, Kyoto 610-0321, Japan. hkitagis@mail.doshisha.ac.jp.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kitagishi
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Chai
authors.forename: Shigeru
authors.initials: S
authors.lastname: Negi
authors.forename: Yukio
authors.initials: Y
authors.lastname: Sugiura
authors.forename: Koji
authors.initials: K
authors.lastname: Kano
mesh_terms: D000838:Anions / Q000737:chemistry; D002384:Catalysis; D002470:Cell Survival / Q000187:drug effects; D057846:Cell-Penetrating Peptides / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D005434:Flow Cytometry; D006367:HeLa Cells; D006801:Humans; D009842:Oligopeptides / Q000737:chemistry*; D011166:Porphyrins / Q000737:chemistry* / Q000378:metabolism / Q000633:toxicity; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D000838:Anions; D057846:Cell-Penetrating Peptides; D009842:Oligopeptides; D011166:Porphyrins; D047392:beta-Cyclodextrins; C108732:methyl-beta-cyclodextrin; C448619:octaarginine; D003300:Copper