title: Serological evidence of avian influenza virus and canine influenza virus infections among stray cats in live poultry markets, China.
abstract: From January 2010 to January 2012, we collected sera samples from 700 stray cats living in close proximity to poultry farms or poultry markets in 4 provinces in China. A number of cats had evidence of avian and canine influenza virus infection: avian H9N2 [24 by HI ≥1:20 and 16 by microneutralization (MN) assay ≥1:80]; avian H5N1 (9 by HI ≥1:20 and 3 by MN assay ≥1:80) and canine H3N2 (32 by HI ≥1:20 and 18 by MN ≥1:80). Bivariate analyses revealed that cats sampled near live poultry markets and cats with influenza-like-illness were at increased risk of having elevated antibody titers by HI against avian H9N2, avian H5N1, or canine H3N2 viruses. Hence, cats may play a very important role in the ecology of novel influenza viruses and periodic epidemiological surveillance for novel influenza infections among stray cats could serve as an early warning system for human threats.
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Han
authors.initials: H
authors.lastname: Zhou
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Shu-yi
authors.initials: SY
authors.lastname: He
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Lingshuang
authors.initials: L
authors.lastname: Sun
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Huamei
authors.initials: H
authors.lastname: He
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Fangxiao
authors.initials: F
authors.lastname: Ji
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Yao
authors.initials: Y
authors.lastname: Sun
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Kun
authors.initials: K
authors.lastname: Jia
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Zhangyong
authors.initials: Z
authors.lastname: Ning
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Heng
authors.initials: H
authors.lastname: Wang
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Liguo
authors.initials: L
authors.lastname: Yuan
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China.
authors.forename: Pei
authors.initials: P
authors.lastname: Zhou
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China. Electronic address: guihongzh@scau.edu.cn.
authors.forename: Guihong
authors.initials: G
authors.lastname: Zhang
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province 510642, People's Republic of China. Electronic address: shoujunli@scau.edu.cn.
authors.forename: Shoujun
authors.initials: S
authors.lastname: Li
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000453:epidemiology / Q000821:virology*; D002415:Cats; D002681:China / Q000453:epidemiology; D009980:Influenza A virus / Q000235:genetics / Q000302:isolation & purification*; D005585:Influenza in Birds / Q000821:virology; D009976:Orthomyxoviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny; D011200:Poultry / Q000821:virology
keywords: Cats; First report; H5N1; LPM