title: Immunotherapy toxic in obese mice.
abstract: New research shows immunotherapy can cause lethal inflammation in both young and aged mice that are obese. Restricting calories in aged mice protected them from toxicity, and giving young obese mice a drug for autoimmune disease prevented the fatal reactions.
mesh_terms: D000818:Animals; D007167:Immunotherapy / Q000009:adverse effects*; D007249:Inflammation / Q000209:etiology; D051379:Mice; D008820:Mice, Obese; D009369:Neoplasms / Q000150:complications / Q000628:therapy; D009765:Obesity