title: The effects of exercise training programs on plasma concentrations of proenkephalin Peptide F and catecholamines.
abstract: To determine if exercise training alters the pattern and magnitude of plasma concentrations of proenkephalin Peptide F and epinephrine, plasma proenkephalin [107-140] Peptide F(ir) and catecholamines were examined pre-training (T-1), and after 4- (T-2), 8- (T-3), and 12-weeks (T-4) of training. 26 healthy men were matched and randomly assigned to one of three groups: heavy resistance strength training (Strength, n=9), high intensity endurance training (Endurance, n=8), or both training modalities combined (Combined, n=9). Blood was collected using a syringe with a cannula inserted into a superficial arm vein with samples collected at rest, after each 7 min stage and 5 and 15 min into recovery. With training, all groups observed shifted plasma Peptide F responses to graded exercise, where significant increases were observed at lower exercise intensities. Increases in plasma epinephrine with exercise were observed in all groups. The Combined group saw increases at 25% at T-3 and for 50% at T-2, T-3, and T-4 which was higher than T-1. The Endurance group demonstrated increases for 50% at T-1, T-2, T-3 but not at T-4. The plasma epinephrine response to graded exercise was reduced in the Strength group. Increases in plasma norepinephrine above rest were observed starting at 50% . The Strength group demonstrated a significant reduction in norepinephrine observed at 100% at T-3 and T-4. Peptide F and catecholamines responses to graded exercise can be altered by different types of physical exercise training. Simultaneous high intensity training may produce adrenal medulla exhaustion when compared to single mode training.
authors.affiliation: Department of Human Sciences, The Ohio State University, Columbus, OH 43210, United States. Electronic address: kraemer.44@osu.edu.
authors.forename: William J
authors.initials: WJ
authors.lastname: Kraemer
authors.affiliation: Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, United States.
authors.forename: Scott E
authors.initials: SE
authors.lastname: Gordon
authors.affiliation: Athlete Health & Performance, Sports and Human Performance Diagnostics, Quest Diagnostics, Madison, NJ 07940, United States.
authors.forename: Maren S
authors.initials: MS
authors.lastname: Fragala
authors.affiliation: Department of Health and Exercise Science, The College of New Jersey, Ewing, NJ 08618, United States.
authors.forename: Jill A
authors.initials: JA
authors.lastname: Bush
authors.affiliation: Department of Human Sciences, The Ohio State University, Columbus, OH 43210, United States.
authors.forename: Tunde K
authors.initials: TK
authors.lastname: Szivak
authors.affiliation: Department of Human Sciences, The Ohio State University, Columbus, OH 43210, United States.
authors.forename: Shawn D
authors.initials: SD
authors.lastname: Flanagan
authors.affiliation: Department of Human Sciences, The Ohio State University, Columbus, OH 43210, United States.
authors.forename: David R
authors.initials: DR
authors.lastname: Hooper
authors.affiliation: Department of Kinesiology, University of Connecticut, Storrs, CT 06269, United States.
authors.forename: David P
authors.initials: DP
authors.lastname: Looney
authors.affiliation: Department of Health & Exercise Science, Appalachian State University, Boone, NC 28608, United States.
authors.forename: N Travis
authors.initials: NT
authors.lastname: Triplett
authors.affiliation: Department of Human Sciences, The Ohio State University, Columbus, OH 43210, United States.
authors.forename: William H
authors.initials: WH
authors.lastname: DuPont
authors.affiliation: Exercise Physiology Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760, United States.
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Dziados
authors.affiliation: Exercise Physiology Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760, United States.
authors.forename: Louis J
authors.initials: LJ
authors.lastname: Marchitelli
authors.affiliation: Exercise Physiology Division, U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760, United States.
authors.forename: John F
authors.initials: JF
authors.lastname: Patton
mesh_terms: D000313:Adrenal Medulla / Q000378:metabolism; D000328:Adult; D002395:Catecholamines / Q000097:blood*; D004744:Enkephalin, Methionine / Q000031:analogs & derivatives* / Q000097:blood; D004745:Enkephalins / Q000097:blood; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008297:Male; D011498:Protein Precursors / Q000097:blood*; D055815:Young Adult
chemical_list: D002395:Catecholamines; D004745:Enkephalins; D011498:Protein Precursors; C029992:proenkephalin; D004744:Enkephalin, Methionine; C036452:peptide F
keywords: Endurance training; Epinephrine; Norepinephrine; Opioid peptides; Proenkephalins; Resistance training