title: Mitral valve repair for congenital mitral valve disease: impact of the use of a biodegradable annuloplasty ring.
abstract: BACKGROUND
  This study compares the midterm results of mitral valve repair using the biodegradable ring versus repair with non-ring annuloplasty techniques for congenital mitral valve disease in young children where it was not possible to use standard commercial rings.
  
  
  METHODS
  Between February 2006 and November 2011, 68 patients underwent mitral valve repair for congenital mitral valve disease. Thirty-nine (57%) patients underwent concomitant annuloplasty using the biodegradable ring (group A) and 29 (43%) patients using non-ring annuloplasty techniques (group B). The median age of repair was 2 years (range 1 month to 14 years).
  
  
  RESULTS
  There were no hospital deaths or major postoperative morbidity. At a median follow-up of 3.8 years (range, 2 months to 5.1 years), overall survival at 5 years was 97% ± 3% for group A and 88% ± 8% for group B (p = 0.29). Freedom from valve failure was 90% ± 7% in group A and 74% ± 9% in group B (p = 0.026). The freedom from reoperation was 100% in group A and 84% ± 9% in group B (p = 0.04). The mean transmitral gradients were 4.3 ± 1.8 mm Hg in group A and 4.2 ±1.7 mm Hg in group B (p = 0.77).
  
  
  CONCLUSIONS
  Mitral valve repair using the biodegradable ring for congenital mitral valve disease was superior compared with non-ring annuloplasty repair. Excellent survival benefit, freedom from reoperation, and valve failure without significant elevation of transmitral gradients, suggests its important role in young children with smaller annular sizes where standard commercial rings are not available or recommended.
authors.affiliation: Department of Cardiothoracic Surgery, National Heart Institute, Kuala Lumpur, Malaysia.
authors.forename: Mohd Azhari
authors.initials: MA
authors.lastname: Yakub
authors.affiliation: Department of Cardiothoracic Surgery, National Heart Institute, Kuala Lumpur, Malaysia. Electronic address: sivakumar@ijn.com.my.
authors.forename: Sivakumar
authors.initials: S
authors.lastname: Sivalingam
authors.affiliation: Department of Cardiothoracic Surgery, National Heart Institute, Kuala Lumpur, Malaysia.
authors.forename: Jeswant
authors.initials: J
authors.lastname: Dillon
authors.affiliation: Department of Cardiothoracic Surgery, National Heart Institute, Kuala Lumpur, Malaysia.
authors.forename: Minoru
authors.initials: M
authors.lastname: Matsuhama
authors.affiliation: Department of Pediatric Cardiology, National Heart Institute, Kuala Lumpur, Malaysia.
authors.forename: Haifa Abdul
authors.initials: HA
authors.lastname: Latiff
authors.affiliation: Department of Clinical Research, National Heart Institute, Kuala Lumpur, Malaysia.
authors.forename: Mohd Faizal
authors.initials: MF
authors.lastname: Ramli
mesh_terms: D020341:Absorbable Implants; D005260:Female; D006349:Heart Valve Diseases / Q000151:congenital* / Q000601:surgery*; D006350:Heart Valve Prosthesis; D006801:Humans; D007223:Infant; D008297:Male; D008943:Mitral Valve / Q000601:surgery*; D058386:Mitral Valve Annuloplasty; D011474:Prosthesis Design; D012189:Retrospective Studies