title: [A woman with gingival hyperplasia].
abstract: A woman visited her dentist with complaints of swollen gums. If there was a serious infection of multiple teeth, the surgeon had to do a total extraction of the upper jaw. The clinical picture was suspicious for a lymphoma, a fibromatosis or a gingivitis. The biopsy showed a chronical infection. In this case the gingival overgrowth and the subsequent infection of the teeth were caused by nifedipine. Gingival enlargement can be a consequence of the administration of calcium channel blockers and can occur if these are administered during a few months or years. The incidence is 0,01-0,1% and the prevalence is 20%. Drug substitution should be considered a valid treatment option and can be successful within a few weeks.
authors.affiliation: Huisartsenpraktijk van Montfort/van der Reijden, Heemskerk.
authors.forename: Monique
authors.initials: M
authors.lastname: van Montfort
authors.forename: Linette
authors.initials: L
authors.lastname: Huisman
mesh_terms: D000368:Aged; D002121:Calcium Channel Blockers / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005885:Gingival Hyperplasia / Q000139:chemically induced* / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D009543:Nifedipine / Q000009:adverse effects* / Q000627:therapeutic use; D015995:Prevalence
chemical_list: D002121:Calcium Channel Blockers; D009543:Nifedipine