title: Effect of feeding peroxidized dried distillers grains with solubles to sows and progeny on growth performance and metabolic oxidative status of nursery pigs.
abstract: This experiment evaluated the effects of including peroxidized corn dried distillers grains with solubles (DDGS) in diets for sows and nursery pigs on growth performance, vitamin E (VE), and Se status, and the incidence of mulberry heart disease (MHD) of nursery pigs. Sows (n = 12) were fed corn-soybean meal diets (C-SBM) or C-SBM diets with DDGS (40% and 20% in gestation and lactation, respectively) for 3 parities. In the third parity, 108 weaned pigs (BW = 6.6 ± 0.36 kg) were blocked by BW within litter, assigned to pens (2 pigs/pen; 5 and 4 pens per litter for groups 1 and 2, respectively), and pens were assigned 1 of 3 nursery diets: 1) corn-soybean meal (CON), 2) 30% peroxidized DDGS (Ox-D), and 3) 30% Ox-D with 5 × NRC (1998) level of VE (Ox-D+5VE) for 7 wk, in a 2 × 3 factorial arrangement of sow and nursery diets (n = 9 pens/treatment). The peroxidized DDGS source in nursery diets contained concentrations of thiobarbituric acid reactive substances (TBARS) and peroxide values that were 25 and 27 times greater than a reference corn sample. Sow colostrum, milk, and serum, as well as pig serum and liver samples, were analyzed for α-tocopherol and Se concentrations. Pig serum was analyzed for glutathione peroxidase activity (GPx), TBARS, and sulfur-containing AA (SAA). Pig hearts were evaluated for gross and histopathological lesions indicative of MHD, but none were detected. Pigs from sows fed DDGS tended to have reduced (P = 0.07) VE in serum during lactation and reduced VE at weaning (P < 0.01; 5.6 vs. 6.7 ± 0.1 µg/mL) compared with pigs from sows fed C-SBM. Inclusion of DDGS in sow diets reduced the VE status of pigs during lactation, but not in the nursery when MHD can be a concern. Pigs fed Ox-D+5VE (P = 0.08) tended to have, and those fed Ox-D (P = 0.04) had greater ADFI than pigs fed CON, but ADG was not affected (P > 0.1) by nursery diet. Feeding Ox-D or Ox-D+5VE increased (P < 0.05) serum α-tocopherol compared with CON (2.5, 2.8, and 3.4 ± 0.09 µg/mL, respectively), but TBARS and GPx were not affected by nursery diet. Serum concentration of SAA was 40% to 50% greater (P < 0.01) for pigs fed Ox-D or Ox-D+5VE compared with those fed C-SBM, which was likely due to greater (P < 0.01) SAA intake for pigs fed Ox-D. The antioxidant properties of SAA may have spared VE and Se and masked any effect of Ox-D on metabolic oxidation status. Therefore, increasing the dietary VE concentration was unnecessary in nursery diets containing Ox-D.
authors.affiliation: Department of Animal Science, University of Minnesota, St. Paul 55108.
authors.forename: A R
authors.initials: AR
authors.lastname: Hanson
authors.affiliation: Department of Food Science and Nutrition, University of Minnesota, St. Paul 55108.
authors.forename: L
authors.initials: L
authors.lastname: Wang
authors.affiliation: West Central Research and Outreach Center, University of Minnesota, Morris 56267.
authors.forename: L J
authors.initials: LJ
authors.lastname: Johnston
authors.affiliation: Southern Research and Outreach Center, University of Minnesota, Waseca 56093.
authors.forename: S K
authors.initials: SK
authors.lastname: Baidoo
authors.affiliation: Veterinary Diagnostic Laboratory, University of Minnesota, St. Paul 55108.
authors.forename: J L
authors.initials: JL
authors.lastname: Torrison
authors.affiliation: Department of Animal Science, University of Minnesota, St. Paul 55108.
authors.forename: C
authors.initials: C
authors.lastname: Chen
authors.affiliation: Department of Animal Science, University of Minnesota, St. Paul 55108 shurs001@umn.edu.
authors.forename: G C
authors.initials: GC
authors.lastname: Shurson
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D019069:Cell Respiration / Q000187:drug effects / Q000502:physiology*; D003126:Colostrum / Q000378:metabolism; D004032:Diet / Q000662:veterinary*; D002523:Edible Grain / Q000737:chemistry; D005260:Female; D007774:Lactation; D008892:Milk / Q000378:metabolism; D010084:Oxidation-Reduction; D011247:Pregnancy; D013025:Glycine max / Q000737:chemistry; D013455:Sulfur / Q000378:metabolism; D034421:Sus scrofa / Q000254:growth & development*; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology*; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D014810:Vitamin E / Q000378:metabolism; D014811:Vitamin E Deficiency / Q000453:epidemiology / Q000662:veterinary*; D014886:Weaning; D003313:Zea mays / Q000737:chemistry; D024502:alpha-Tocopherol / Q000097:blood / Q000378:metabolism
chemical_list: D000975:Antioxidants; D017392:Thiobarbituric Acid Reactive Substances; D014810:Vitamin E; D013455:Sulfur; D024502:alpha-Tocopherol
keywords: Mulberry Heart Disease; dried distillers grains with solubles; growth performance; pigs; sows; vitamin E