title: Transforaminal lumbar interbody fusion rates in patients using a novel titanium implant and demineralized cancellous allograft bone sponge.
abstract: BACKGROUND
  Transforaminal lumbar interbody fusion (TLIF) with grafting and implant options like iliac crest bone graft (ICBG), recombinant bone morphogenetic protein (rhBMP), and polyetheretherketone (PEEK) cages have been reported to achieve extremely high fusion rates. Unfortunately, these options have also been frequently cited in the literature as causing postoperative morbidity and complications at a high cost. Knowing this, we sought to investigate TLIF using an acid-etched, roughened titanium cage that upregulates osteogenesis to see if similar fusion rates to those cited for ICBG, rhBMP, and PEEK cages could be safely achieved with minimal morbidity and complications.
  
  
  METHODS
  A radiographic fusion study of 82 patients who underwent TLIF using an acid-etched, roughened titanium cage with demineralized cancellous bone graft was conducted. Fusion was assessed and graded by an independent radiologist using computed tomography scan with sagittal and coronal reconstructions.
  
  
  RESULTS
  Fusion rates at 6 months were 41 of 44 (93.2%) and at 12 months were 37 of 38 (97.4%). There were no radiographic device-related complications.
  
  
  CONCLUSIONS
  TLIF with an acid-etched, roughened titanium cage filled with a decalcified bone graft achieved similar fusion rates to historical controls using ICBG, rhBMP, and PEEK.
authors.affiliation: Orthopaedic and Sports Medical Center, Trumbull, CT.
authors.forename: Gerard
authors.initials: G
authors.lastname: Girasole
authors.affiliation: Orthopaedic and Sports Medical Center, Trumbull, CT.
authors.forename: Gerard
authors.initials: G
authors.lastname: Muro
authors.affiliation: Orthopaedic and Sports Medical Center, Trumbull, CT.
authors.forename: Abraham
authors.initials: A
authors.lastname: Mintz
authors.affiliation: Department of Internal Medicine, University of Florida College of Medicine, Gainesville, FL.
authors.forename: Jason
authors.initials: J
authors.lastname: Chertoff
keywords: Fusion; Graft; Iliac crest bone graft (ICBG); Lumbar; PEEK cage; Recombinant human bone morphogenetic protein (rhBMP); TLIF