title: Generalized lymphadenopathy and 18-fluorine fluorodeoxyglucose positron emission tomography/computed tomography: targeting diagnostic intervention, characterizing disease extent, and assessing treatment efficacy in syphilis.
abstract: 18-Fluorine fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) has been shown to have use in the diagnosis of inflammatory and infectious diseases in addition to its primary use in cancer. We describe a case of early neurosyphilis that initially presented as symmetric, generalized lymphadenopathy on PET/CT. We conclude that PET/CT may play a role in evaluating targeted diagnostic interventions, disease extent, and treatment efficacy for disseminated syphilis.
authors.affiliation: From the *Departments of Nuclear Medicine, †Medicine, and ‡Pathology, New Jersey Medical School, Rutgers University, Newark, NJ.
authors.forename: Praveen
authors.initials: P
authors.lastname: Ranganath
authors.forename: Rajendra
authors.initials: R
authors.lastname: Kapila
authors.forename: Vivek
authors.initials: V
authors.lastname: Vadehra
authors.forename: Qing
authors.initials: Q
authors.lastname: Wang
authors.forename: Eugenio
authors.initials: E
authors.lastname: Capitle
authors.forename: Nasrin
authors.initials: N
authors.lastname: Ghesani
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003937:Diagnosis, Differential; D019788:Fluorodeoxyglucose F18; D006801:Humans; D056965:Injections, Intraocular; D008199:Lymphadenitis / Q000150:complications / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009494:Neurosyphilis / Q000150:complications / Q000000981:diagnostic imaging*; D010400:Penicillin G / Q000008:administration & dosage; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D015354:Vision, Low / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000209:etiology; D051598:Whole Body Imaging
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D010400:Penicillin G