title: Laboratory identification of donor-derived coxsackievirus b3 transmission.
abstract: Unexpected donor-to-recipient infectious disease transmission is an important, albeit rare, complication of solid organ transplantation. Greater work and understanding about the epidemiology of these donor-derived transmissions is continually required to further mitigate this risk. Herein we present the first reported case of proven donor-derived transmission of coxsackievirus serogroup-3, an enterovirus, following solid organ transplant. Swift and effective communication between the organ donation agency, treating physicians, laboratory testing and notification ensured a coordinated approach. The resulting clinical syndromes in the organ recipients were mild. This case highlights the requirement for ongoing surveillance over a broad range of infecting pathogens that may present as a donor-derived infection.
authors.affiliation: Victorian Infectious Diseases Reference Laboratory, Melbourne, Australia.
authors.forename: I J
authors.initials: IJ
authors.lastname: Abbott
authors.forename: G
authors.initials: G
authors.lastname: Papadakis
authors.forename: M
authors.initials: M
authors.lastname: Kaye
authors.forename: H
authors.initials: H
authors.lastname: Opdam
authors.forename: H
authors.initials: H
authors.lastname: Hutton
authors.forename: P W
authors.initials: PW
authors.lastname: Angus
authors.forename: P D R
authors.initials: PD
authors.lastname: Johnson
authors.forename: J
authors.initials: J
authors.lastname: Kanellis
authors.forename: G
authors.initials: G
authors.lastname: Westall
authors.forename: J
authors.initials: J
authors.lastname: Druce
authors.forename: M
authors.initials: M
authors.lastname: Catton
mesh_terms: D000328:Adult; D001706:Biopsy; D003384:Coxsackievirus Infections / Q000635:transmission*; D029822:Enterovirus B, Human / Q000302:isolation & purification / Q000472:pathogenicity*; D006801:Humans; D007668:Kidney / Q000473:pathology / Q000821:virology; D016030:Kidney Transplantation; D008099:Liver / Q000473:pathology / Q000821:virology; D016031:Liver Transplantation; D008168:Lung / Q000473:pathology / Q000821:virology; D016040:Lung Transplantation; D010179:Pancreas / Q000473:pathology / Q000821:virology; D016035:Pancreas Transplantation; D014019:Tissue Donors; D066027:Transplant Recipients
keywords: Clinical research/practice; donors and donation: donor-derived infections; infection and infectious agents; infectious disease; viral