title: Disseminated adenovirus disease in heart transplant recipient presenting with conjunctivitis.
abstract: We report a 65-year-old heart transplant recipient who presented with conjunctivitis, likely acquired from a family member who worked at a daycare center during an outbreak of conjunctivitis. He developed a severe adenoviral pneumonitis, which was successfully treated with intravenous cidofovir combined with a reduction of immunosuppression.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: J
authors.initials: J
authors.lastname: Bruminhent
authors.forename: D M
authors.initials: DM
authors.lastname: Athas
authors.forename: B D
authors.initials: BD
authors.lastname: Hess
authors.forename: P
authors.initials: P
authors.lastname: Flomenberg
mesh_terms: D000258:Adenovirus Infections, Human / Q000188:drug therapy*; D000260:Adenoviruses, Human / Q000187:drug effects; D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use*; D000077404:Cidofovir; D003231:Conjunctivitis / Q000188:drug therapy*; D003596:Cytosine / Q000031:analogs & derivatives / Q000627:therapeutic use; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008297:Male; D063065:Organophosphonates / Q000627:therapeutic use; D011024:Pneumonia, Viral / Q000188:drug therapy*; D011183:Postoperative Complications / Q000188:drug therapy*; D066027:Transplant Recipients
chemical_list: D000998:Antiviral Agents; D063065:Organophosphonates; D003596:Cytosine; D000077404:Cidofovir
keywords: adenovirus; cidofovir; conjunctivitis; heart transplantation; pneumonitis