title: Outcome determinants of stroke in a brazilian primary stroke center.
abstract: Background. Stroke mortality in Brazil is one of the highest among Western countries. Nonetheless, stroke outcome determinants are still poorly known in this country. In this study we evaluate outcome determinants of stroke in a primary stroke center in São Paulo, Brazil. Methods. We evaluated demographic, clinical, and outcome data of patients with ischemic stroke (IS), transient ischemic attack (TIA), and intracerebral hemorrhage (ICH) admitted at "Hospital Paulistano," São Paulo, Brazil. In-hospital mortality and functional outcome determinants were assessed. Univariate and binary logistic regression analysis were performed. Results. Three hundred forty-one patients were included in the study, 52.2% being male with 66.8 ± 15.7 years. The stroke type distribution was IS: 59.2%, TIA: 29.6%, and ICH: 11.1%. ICH was associated with greater severity and poorer functional outcome. The determinants of poorer functional outcome were higher NIHSS, lower Glasgow score, and lower oxygen saturation level. The most important mortality determinant was the presence of visual symptoms. Conclusions. The stroke mortality and stroke outcome determinants found in the present study do not remarkably differ from studies carried out in developed countries. Stroke prognosis studies are crucial to better understand the high burden of stroke in Brazil.
authors.affiliation: Hospital Paulistano, 01321-001 São Paulo, SP, Brazil ; Stroke Integrated Program (PIAVEN), Amil Stroke Network, 01321-001 São Paulo, SP, Brazil ; Department of Neurology, Faculdade de Medicina do ABC, 09060-650 Santo André, SP, Brazil.
authors.forename: Gustavo W
authors.initials: GW
authors.lastname: Kuster
authors.affiliation: Hospital Paulistano, 01321-001 São Paulo, SP, Brazil ; Stroke Integrated Program (PIAVEN), Amil Stroke Network, 01321-001 São Paulo, SP, Brazil ; Department of Neurology, Federal University of São Paulo (UNIFESP), 04021-001 São Paulo, SP, Brazil.
authors.forename: Lívia A
authors.initials: LA
authors.lastname: Dutra
authors.affiliation: Hospital Paulistano, 01321-001 São Paulo, SP, Brazil ; Stroke Integrated Program (PIAVEN), Amil Stroke Network, 01321-001 São Paulo, SP, Brazil.
authors.forename: Israel P
authors.initials: IP
authors.lastname: Brasil
authors.affiliation: Hospital Paulistano, 01321-001 São Paulo, SP, Brazil ; Stroke Integrated Program (PIAVEN), Amil Stroke Network, 01321-001 São Paulo, SP, Brazil.
authors.forename: Evelyn P
authors.initials: EP
authors.lastname: Pacheco
authors.affiliation: Hospital Paulistano, 01321-001 São Paulo, SP, Brazil.
authors.forename: Márcio A C
authors.initials: MA
authors.lastname: Arruda
authors.affiliation: Hospital Paulistano, 01321-001 São Paulo, SP, Brazil ; Stroke Integrated Program (PIAVEN), Amil Stroke Network, 01321-001 São Paulo, SP, Brazil.
authors.forename: Cristiane
authors.initials: C
authors.lastname: Volcov
authors.affiliation: Hospital Paulistano, 01321-001 São Paulo, SP, Brazil ; Stroke Integrated Program (PIAVEN), Amil Stroke Network, 01321-001 São Paulo, SP, Brazil ; Neurosciences Program, Federal University of Minas Gerais (UFMG), 31270-901 Belo Horizonte, MG, Brazil.
authors.forename: Renan B
authors.initials: RB
authors.lastname: Domingues