title: Cancer of the sigmoid colon and antibodies. A puzzle.
abstract: In this work we describe the case report of a woman affected by cancer of the sigmoid colon and with a positive direct antiglobulin test (DAT) and indirect antiglobulin test (IAT). Case report with results: A meticulous medical history showed that the woman had been suffering from recurrent fetal loss. Then she had cardiac and coagulative problems. These data suggested a phospholipid syndrome.
  
  
  CONCLUSIONS
  The patient had a medical history positive for a phospholipid syndrome and we think that this disease could explain the onset of the autoantibody.
authors.affiliation: SIMT Tor Vergata Hospital, Rome, Italy. Electronic address: delpropostog@gmail.com.
authors.forename: Gianpaolo
authors.initials: G
authors.lastname: Del Proposto
authors.affiliation: Immunohematology Section, Tor Vergata University, Rome, Italy.
authors.forename: Maddalena
authors.initials: M
authors.lastname: Antonelli
authors.affiliation: SIMT Tor Vergata Hospital, Rome, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Cerrone
authors.affiliation: Hematology Section, Tor Vergata University, Rome, Italy.
authors.forename: Antoine
authors.initials: A
authors.lastname: Bruno
authors.affiliation: Immunohematology Section, Tor Vergata University, Rome, Italy.
authors.forename: Laila
authors.initials: L
authors.lastname: Costantino
authors.affiliation: General Surgery Section, Tor Vergata University, Rome, Italy.
authors.forename: Edoardo
authors.initials: E
authors.lastname: Ricciardi
authors.affiliation: General Surgery Section, Tor Vergata University, Rome, Italy.
authors.forename: Piero
authors.initials: P
authors.lastname: Rossi
authors.affiliation: Internal Medicine, Tor Vergata University, Rome, Italy.
authors.forename: Stella
authors.initials: S
authors.lastname: Modica
authors.affiliation: SIMT Tor Vergata Hospital, Immunohematology Section, Tor Vergata University, Rome, Italy.
authors.forename: Gaspare
authors.initials: G
authors.lastname: Adorno
mesh_terms: D000026:Abortion, Habitual; D000369:Aged, 80 and over; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications; D000906:Antibodies / Q000097:blood*; D016736:Antiphospholipid Syndrome / Q000150:complications; D001323:Autoantibodies / Q000097:blood; D001778:Blood Coagulation Disorders / Q000150:complications; D002318:Cardiovascular Diseases / Q000150:complications; D012809:Colon, Sigmoid / Q000276:immunology* / Q000473:pathology*; D003113:Colonoscopy; D003298:Coombs Test; D005260:Female; D006801:Humans; D012811:Sigmoid Neoplasms / Q000175:diagnosis* / Q000276:immunology*
chemical_list: D000906:Antibodies; D001323:Autoantibodies
keywords: Autoantibody; Autoimmune hemolitic anemia; Cancer of the sigmoid colon; Phospholipids; Syndrome