title: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in mediastinal lymphadenopathy.
abstract: Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration (EBUS-TBNA) is accepted as a safe and minimally invasive modality for evaluation of mediastinal pathologies in adults. There is scanty literature on the utilization and performance characteristics of Convex probe EBUS-TBNA in children. The authors herein describe two pediatric patients with mediastinal lymphadenopathy wherein the underlying diagnosis was unclear based on the clinico-radiological profile. A possibility of lymphoma was considered in one of the patients. EBUS-TBNA was performed for obtaining tissue samples from the enlarged mediastinal lymph nodes and diagnosis of tuberculosis was established in both the patients. The authors review the available literature on Pediatric EBUS TBNA. EBUS-TBNA is an exciting and promising approach towards safe and accurate evaluation of mediastinal pathologies in children. Pediatric EBUS-TBNA needs further evaluation in prospective studies.
authors.affiliation: Department of Pulmonary Medicine and Sleep Disorders, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India, drkaranmadan@gmail.com.
authors.forename: Karan
authors.initials: K
authors.lastname: Madan
authors.forename: Irfan Ismail
authors.initials: II
authors.lastname: Ayub
authors.forename: Anant
authors.initials: A
authors.lastname: Mohan
authors.forename: Deepali
authors.initials: D
authors.lastname: Jain
authors.forename: Randeep
authors.initials: R
authors.lastname: Guleria
authors.forename: Sushil K
authors.initials: SK
authors.lastname: Kabra
mesh_terms: D000904:Antibiotics, Antitubercular / Q000008:administration & dosage; D001999:Bronchoscopy / Q000379:methods*; D002648:Child; D003937:Diagnosis, Differential; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000379:methods*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000382:microbiology / Q000473:pathology; D008297:Male; D008477:Mediastinal Diseases / Q000175:diagnosis / Q000473:pathology; D008482:Mediastinum / Q000473:pathology*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D012293:Rifampin / Q000008:administration & dosage*; D016896:Treatment Outcome; D014388:Tuberculosis, Lymph Node / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology
chemical_list: D000904:Antibiotics, Antitubercular; D012293:Rifampin