title: Spinal cord glioneuronal tumor with rosetted neuropil-like islands in pediatric age group.
abstract: Glioneuronal neoplasms are rare tumors. Recently, an unusual glioneuronal tumor histologically showing neuropil-like islands has been described. Here, we present such a tumor originating from spinal cord of a 14-year-old girl, who has scoliosis and urinary incontinence. Microscopically, the glial component was chiefly fibrillary astrocytic, punctuated by neuropil-like islands. Immunohistochemically, glial tissue was GFAP positive, and neuropil-like areas and big neurons were synaptophysin reactive. For astrocytic component Ki-67 proliferation index was 1% and p53 was immunonegative. This case is unique in that in the literature it is the second reported case in pediatric age group that is located at spinal cord.
authors.affiliation: Department of Pathology, Cerrahpasa Faculty of Medicine, Istanbul University, 34000 Istanbul, Turkey.
authors.forename: Nil
authors.initials: N
authors.lastname: Comunoglu
authors.affiliation: Department of Radiology, Faculty of Medicine, Yeditepe University, Istanbul, Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Kilickesmez
authors.affiliation: Department of Pathology, Cerrahpasa Faculty of Medicine, Istanbul University, 34000 Istanbul, Turkey.
authors.forename: Buge
authors.initials: B
authors.lastname: Oz