title: PLGA: a unique polymer for drug delivery.
abstract: Biodegradable polymers have played an important role in the delivery of drugs in a controlled and targeted manner. Polylactic-co-glycolic acid (PLGA) is one of the extensively researched synthetic biodegradable polymers due to its favorable properties. It is also known as a 'Smart Polymer' due to its stimuli sensitive behavior. A wide range of PLGA-based drug delivery systems have been reported for the treatment or diagnosis of various diseases and disorders. The present review provides an overview of the chemistry, physicochemical properties, biodegradation behavior, evaluation parameters and applications of PLGA in drug delivery. Different drug-polymer combinations developed into drug delivery or carrier systems are enumerated and discussed.
authors.affiliation: School of Pharmaceutical Sciences (LSPS), Faculty of Applied Medical Sciences (LFAMS), Lovely Professional University (LPU), Phagwara, Punjab, India.
authors.forename: Deepak N
authors.initials: DN
authors.lastname: Kapoor
authors.forename: Amit
authors.initials: A
authors.lastname: Bhatia
authors.forename: Ripandeep
authors.initials: R
authors.lastname: Kaur
authors.forename: Ruchi
authors.initials: R
authors.lastname: Sharma
authors.forename: Gurvinder
authors.initials: G
authors.lastname: Kaur
authors.forename: Sanju
authors.initials: S
authors.lastname: Dhawan
mesh_terms: D001673:Biodegradation, Environmental; D016503:Drug Delivery Systems; D019344:Lactic Acid / Q000138:chemical synthesis / Q000737:chemistry; D053758:Nanoparticles; D011100:Polyglycolic Acid / Q000138:chemical synthesis / Q000737:chemistry; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer
chemical_list: D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid