title: Verruca vulgaris: novel treatment with a 1064 nm Nd:YAG laser.
abstract: BACKGROUND
  Verruca Vulgaris (VV) is common benign neoplasm. However, it can present a therapeutic challenge. Previous studies have suggested that the Nd-YAG laser may be beneficial in the management of warts.
  
  
  OBJECTIVE
  To determine the effectiveness and safety of a novel 100 microsecond pulsed 1064 nm Nd:YAG laser for the treatment of VV.
  
  
  METHODS
  A total of 25 adult subjects with a total of 63 hand verrucae were enrolled in the clinical trial to receive treatment with a low-energy (200 mjoule) 1064 nm Nd:YAG laser (PinPointe, NuvoLase, Inc.). Each subject was eligible for 3 treatments administered at monthly intervals. All verrucae were measured before each treatment session and at 6 months after the final treatment.
  
  
  RESULTS
  A complete response was seen in 19 subjects and in 41 verrucae. A complete response was defined as complete absence of verruca with the presence of normal skin dermatoglyphics. All other lesions showed at least partial response. A partial response was defined as a 50% or greater reduction in verruca size. No adverse events were noted.
  
  
  CONCLUSIONS
  Low-energy 1064 nm Nd: YAG laser treatment may be a promising, safe, and effective therapeutic modality for the treatment of VV. However, more treatment sessions may be needed for complete clearance and increased efficacy in some subjects.
authors.affiliation: Skin Laser & Surgery Specialists of New York and New Jersey, Westwood, NJ , USA.
authors.forename: David J
authors.initials: DJ
authors.lastname: Goldberg
authors.forename: Angela N
authors.initials: AN
authors.lastname: Beckford
authors.forename: Andrea
authors.initials: A
authors.lastname: Mourin
mesh_terms: D000328:Adult; D003357:Cosmetic Techniques / Q000295:instrumentation*; D005260:Female; D006225:Hand; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D014860:Warts / Q000532:radiotherapy*
keywords: Nd-YAG; lasers; verruca; warts