title: Surface EMG parameters in schizophrenia patients.
abstract: The aim of the study was to compare a variety of surface EMG (sEMG) parameters in several groups of schizophrenia (SZ, n=69) patients and healthy controls (n=44). We computed spectral, mutual information (MI) based and recurrence quantification analysis (RQA) parameters of sEMG. The major finding is that sEMG of the controls had higher values of the MI-based parameter, mean and median spectrum frequencies, and lower values of most of RQA parameters. It means higher content of recurrent fragments in sEMG of SZ patients. We suggest that the differences might be caused by either denervation/renervation process of single muscle fibers in SZ patients and/or by increased motor unit synchronization induced by antipsychotic therapy.
authors.forename: German
authors.initials: G
authors.lastname: Miroshnichenko
authors.forename: Anna
authors.initials: A
authors.lastname: Kuzmina
authors.forename: Alexander
authors.initials: A
authors.lastname: Meigal
authors.forename: Mark
authors.initials: M
authors.lastname: Burkin
authors.forename: Saara M
authors.initials: SM
authors.lastname: Rissanen
authors.forename: Pasi A
authors.initials: PA
authors.lastname: Karjalainen
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D004576:Electromyography; D005260:Female; D005542:Forearm; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000502:physiology; D011618:Psychotic Disorders / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D055815:Young Adult
chemical_list: D014150:Antipsychotic Agents