title: Systemic Nocardiosis Mimicking Disease Flare-up after Discontinuation of Gefitinib in a Patient with EGFR-Mutant Lung Cancer.
abstract: Disease flare-up after discontinuing epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) has been considered as a critical issue in lung cancer patients who have experienced radiologic progression after showing initial durable response. This is a case of systemic nocardiosis that occurred after chronic steroid use for radionecrosis from stereotactic radiosurgery. It was initially thought as a disease flare-up after stopping EGFR-TKI.
authors.affiliation: Department of Internal Medicine, Center for Diagnostic Oncology, National Cancer Center, Goyang, Korea.
authors.forename: Mihong
authors.initials: M
authors.lastname: Choi
authors.affiliation: Department of Internal Medicine, Center for Diagnostic Oncology, National Cancer Center, Goyang, Korea.
authors.forename: Youngjoo
authors.initials: Y
authors.lastname: Lee
authors.affiliation: Department of Laboratory Medicine, Center for Diagnostic Oncology, National Cancer Center, Goyang, Korea.
authors.forename: Sang Hyun
authors.initials: SH
authors.lastname: Hwang
authors.affiliation: Department of Internal Medicine, Center for Diagnostic Oncology, National Cancer Center, Goyang, Korea.
authors.forename: Jin Soo
authors.initials: JS
authors.lastname: Lee
keywords: Carcinoma, Non-Small-Cell Lung; EGFR Tyrosine Kinase Inhibitor 324674; Nocardia Infections; Radiosurgery