title: Evaluation of certain veterinary drug residues in food. Seventy-eighth report of the Joint FAO/WHO Expert Committee on Food Additives.
abstract: This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues of food. The first part of the report considers general principles regarding the evaluation of residues of veterinary drugs within the terms of reference of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), including extrapolation of maximum residue limits (MRLs) to minor species, MRLs for veterinary drug residues in honey, MRLs relating to fish and fish species, dietary exposure assessment methodologies, the decision-tree approach to the evaluation of residues of veterinary drugs and guidance for JECFA experts. Summaries follow of the Committee's evaluations of toxicology and residue data on a variety of veterinary drugs: two anthelminthic agents (derquantel, monepantel), three antiparasitic agents (emanectin benzoate, ivermectin, lasalocid sodium), one antibacterial, antifungal and anthelminthic agent (gentian violet), a production aid (recombinant bovine somatotropins) and an adrenoceptor agonist and growth promoter (zilpaterol hydorchloride). Annexed to the report is a summary of the Committee's recommendations on these drugs, including acceptable daily intakes (ADIs)) and proposed MRLs.
mesh_terms: D000322:Adrenergic Agonists / Q000032:analysis; D000890:Anti-Infective Agents / Q000032:analysis; D004350:Drug Residues / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis*; D005523:Food Supply; D013006:Growth Hormone / Q000032:analysis; D006801:Humans; D018570:Risk Assessment; D014480:United Nations; D019155:Veterinary Drugs / Q000032:analysis*; D014944:World Health Organization
chemical_list: D000322:Adrenergic Agonists; D000890:Anti-Infective Agents; D019155:Veterinary Drugs; D013006:Growth Hormone