title: [Predictive value of blood serum cytokines in patients with supratentorial meningiomas].
abstract: OBJECTIVE
  To establish a predictive role of blood serum cytokines and their effect on a clinical picture of patients with supratentorial meningiomas.
  
  
  METHODS
  Levels of interleukin-4, interleukin-6 and γ-interferon were measured in 26 patients using immunoenzymatic method. Assessment of a predictive role of cytokine levels was carried out by a method of the analysis of multidimensional data and cluster analysis on the basis of Kokhonen's neural network. Correlation between cytokine level and scores on the Karnovsky scale at discharge from hospital was used as an indicator of treatment efficacy.
  
  
  RESULTS
  The changes in interleukin-4 level had no impact on a clinical condition of patients while the fluctuations of blood serum played a significant role.
  
  
  CONCLUSIONS
  To predict clinical condition and timely treatment correction in patients with supratentorial meningiomas, monitoring of interleukin-6 and γ-interferon levels is needed.
authors.forename: N S
authors.initials: NS
authors.lastname: Belko
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Kislitsyn
authors.forename: I N
authors.initials: IN
authors.lastname: Fischeva
mesh_terms: D014408:Biomarkers, Tumor / Q000097:blood*; D016207:Cytokines / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008579:Meningioma / Q000175:diagnosis*; D008875:Middle Aged; D015173:Supratentorial Neoplasms / Q000175:diagnosis*
chemical_list: D014408:Biomarkers, Tumor; D016207:Cytokines