title: Multifactorial analysis of local and lymph node recurrences after conservative or radical surgery for stage 0-II breast cancer.
abstract: OBJECTIVE
  Multifactorial analysis of local and lymph node recurrences in stage 0-II breast cancer treated by conservative or radical surgery.
  
  
  METHODS
  In the interval January 1, 2005-July 31, 2013, 477 breast cancer patients were assessed by imaging techniques at the Radiology Clinic of Iasi "Sf. Spiridon" Hospital and Radiology Service of the Iasi Regional Cancer Institute. Of these 229 (48%) patients underwent conservative surgery and 248 (52%) patients radical surgery.
  
  
  RESULTS
  Local recurrences were 2.8 times more frequent in conservatively vs. radically treated patients, and lymph node recurrences 2 times more frequent in patients treated conservatively. Breast tumors larger than 3 cm in diameter were at higher risk for local and distant recurrence in lymph nodes.
  
  
  CONCLUSIONS
  Assessment in patients with local and lymph nodes recurrences of the relative risk for developing other types of recurrences (bone, pleuro pulmonary, liver, brain metastases) indicated that these are a risk factor for other types of recurrences, influencing the prognosis of patients. Local recurrences showed a higher relative risk for other types of recurrences than nodal recurrences.
authors.affiliation: University of Medicine and Pharmacy Grigore T. Popa - Iaşi, Department of Surgery.
authors.forename: Manuela
authors.initials: M
authors.lastname: Ursaru
authors.forename: Irina
authors.initials: I
authors.lastname: Jari
authors.forename: Roxana
authors.initials: R
authors.lastname: Popescu
authors.forename: D
authors.initials: D
authors.lastname: Negru
authors.forename: A
authors.initials: A
authors.lastname: Naum
authors.forename: V
authors.initials: V
authors.lastname: Scripcariu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008408:Mastectomy / Q000379:methods; D015412:Mastectomy, Segmental / Q000379:methods; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery* / Q000628:therapy; D009367:Neoplasm Staging; D011379:Prognosis; D011859:Radiography; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D021701:Sentinel Lymph Node Biopsy; D016896:Treatment Outcome