title: Efficacy of cardiac resynchronization with defibrillator insertion in patients undergone coronary artery bypass graft: a cohort study of cardiac function.
abstract: BACKGROUND
  Cardiac resynchronization therapy (CRT) is a proven therapeutic method in selected patients with heart failure and systolic dysfunction which increases left ventricular function and patient survival. We designed a study that included patients undergoing coronary artery bypass graft (CABG), with and without CRT-defibrillator (CRT-D) inserting and then measured its effects on these two groups.
  
  
  METHODS
  Between 2010 and 2013, we conducted a prospective cohort study on 100 coronary artery disease patients where candidate for CABG. Then based on the receiving CRT-D, the patients were categorized in two groups; Group 1 ( n = 48, with CRT-D insertion before CABG) and Group 2 ( n = 52 without receiving CRT-D). Thereafter both of these groups were followed-up at 1-3 months after CABG for mortality, hospitalization, atrial fibrillation (AF), echocardiographic assessment, and New York Heart Association (NYHA) class level.
  
  
  RESULTS
  The mean age of participants in Group 1 (48 male) and in Group 2 (52 male) was 58 ± 13 and 57 ± 12 respectively. Difference between Groups 1 and 2 in cases of mean left ventricular ejection fraction (LVEF) changes and NYHA class level was significant ( P > 0.05). Hospitalization ( P = 0.008), mortality rate ( P = 0.007), and AF were significantly different between these two groups.
  
  
  CONCLUSIONS
  The results showed that the increase in LVEF and patient's improvement according to NYHA-class was significant in the first group, and readmission, mortality rate and AF was increased significantly in the second group.
authors.forename: Reza
authors.initials: R
authors.lastname: Karbasi Afshar
authors.affiliation: Students' Research Committee, Baqiyatallah University of Medical Science, Tehran, Iran.
authors.forename: Mahdi
authors.initials: M
authors.lastname: Ramezani Binabaj
authors.forename: Mohammad Saeid
authors.initials: MS
authors.lastname: Rezaee Zavareh
authors.forename: Amin
authors.initials: A
authors.lastname: Saburi
authors.forename: Reza
authors.initials: R
authors.lastname: Ajudani
mesh_terms: D000328:Adult; D000368:Aged; D001281:Atrial Fibrillation / Q000150:complications; D058406:Cardiac Resynchronization Therapy / Q000379:methods*; D002315:Cardiopulmonary Bypass / Q000379:methods*; D015331:Cohort Studies; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D005260:Female; D006334:Heart Function Tests; D017052:Hospital Mortality; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011446:Prospective Studies; D013318:Stroke Volume; D016277:Ventricular Function, Left