title: A direct method for the synthesis of orthogonally protected furyl- and thienyl- amino acids.
abstract: The synthesis of unnatural amino acids plays a key part in expanding the potential application of peptide-based drugs and in the total synthesis of peptide natural products. Herein, we report a direct method for the synthesis of orthogonally protected 5-membered heteroaromatic amino acids.
authors.affiliation: Department of Chemistry, Durham University, South Road, Durham, DH1 3LE, UK.
authors.forename: Alex S
authors.initials: AS
authors.lastname: Hudson
authors.forename: Laurent
authors.initials: L
authors.lastname: Caron
authors.forename: Neil
authors.initials: N
authors.lastname: Colgin
authors.forename: Steven L
authors.initials: SL
authors.lastname: Cobb
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000596:Amino Acids; D010455:Peptides