title: A Newly Developed Sublingual Tonometric Method for the Evaluation of Tissue Perfusion and Its Validation In Vitro and in Healthy Persons In Vivo and the Results of the Measurements in COPD Patients.
abstract: Introduction. Since its first publication in the medical literature, an extremely large number of references have demonstrated that the tonometric measurement of tissue perfusion is a reliable indicator of the actual condition of critically ill patients. Later a new method was developed by the introduction of sublingual tonometry for the determination of tissue perfusion. In comparison with gastric tonometry, the new method was simpler and could even be used in awake patients. Unfortunately, at present, because of severe failures of manufacturing, the device is withdrawn from commerce. Materials and Methods. In this study, we present a new method using a newly developed tool for the PslCO2 measurement in sublingual tonometry as well as the data for its validation in vitro and in vivo and the results of 25 volunteers and 54 COPD patients belonging to different GOLD groups at their hospitalization due to the acute exacerbation of the disease but already in a stable condition at the time of the examination. Results and Conclusion. The results of the performed examinations showed that the method is suitable for monitoring the actual condition of the patients by mucosal perfusion tonometry in the sublingual region.
authors.affiliation: Department of Pulmonology, University of Szeged, 36 Alkotmány Street, Deszk 6772, Hungary.
authors.forename: Zoltán
authors.identifier: 0000-0002-2804-2355
authors.initials: Z
authors.lastname: Rózsavölgyi
authors.affiliation: Department of Pediatrics, University of Szeged, Korányi Fasor 14, Szeged 6720, Hungary.
authors.forename: Domokos
authors.identifier: 0000-0002-9450-0422
authors.initials: D
authors.lastname: Boda
authors.affiliation: Department of Pulmonology, University of Szeged, 36 Alkotmány Street, Deszk 6772, Hungary.
authors.forename: Andrea
authors.identifier: 0000-0003-0971-220X
authors.initials: A
authors.lastname: Hajnal
authors.affiliation: Department of Medical Physics and Informatics, University of Szeged, 9 Korányi Fasor, Szeged 6720, Hungary.
authors.forename: Krisztina
authors.identifier: 0000-0002-9937-0460
authors.initials: K
authors.lastname: Boda
authors.affiliation: Department of Pulmonology, University of Szeged, 36 Alkotmány Street, Deszk 6772, Hungary.
authors.forename: Attila
authors.identifier: 0000-0001-5062-8152
authors.initials: A
authors.lastname: Somfay