title: Are QTc interval changes after meal intake a reasonable method to prove assay sensitivity in thorough QT studies?
authors.affiliation: Imperial College, London, England.
authors.forename: Katerina
authors.initials: K
authors.lastname: Hnatkova
authors.affiliation: Global Clinical Pharmacology and Exploratory Development, Astellas Pharma Global Development Inc., Northbrook, IL, USA.
authors.forename: Donna
authors.initials: D
authors.lastname: Kowalski
authors.affiliation: Global Clinical Pharmacology and Exploratory Development, Astellas Pharma Global Development Inc., Northbrook, IL, USA.
authors.forename: James J
authors.initials: JJ
authors.lastname: Keirns
authors.affiliation: Global Clinical Pharmacology and Exploratory Development, Astellas Pharma Europe B.V., Leiden, The Netherlands.
authors.forename: E Marcel
authors.initials: EM
authors.lastname: van Gelderen
authors.affiliation: St. Paul's Cardiac Electrophysiology and Imperial College, London, England. Electronic address: marek.malik@btinternet.com.
authors.forename: Marek
authors.initials: M
authors.lastname: Malik
mesh_terms: D004435:Eating / Q000502:physiology*; D015716:Electrocardiography, Ambulatory / Q000379:methods*; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D019518:Postprandial Period / Q000502:physiology*