title: Estimating quality-adjusted life-year loss due to noncommunicable diseases in Korean adults through to the year 2040.
abstract: OBJECTIVE
  To estimate the loss in quality-adjusted life-years (QALYs) in Korean adults due to 13 noncommunicable diseases (NCDs) in 2010 and predict changes in QALY loss through to the year 2040.
  
  
  METHODS
  Thirteen NCDs (hypertension, diabetes mellitus, hyperlipidemia, stroke, myocardial infarction, angina, arthritis, osteoporosis, asthma, allergic rhinitis, atopic dermatitis, cataract, and depression) were selected from the Korean Community Health Survey 2010. The EuroQol five-dimensional questionnaire index from the Korean Community Health Survey 2010 and the Korean valuation set were used to estimate utility weights according to sex, age, and disease. Morbidity data were also obtained from the Korean Community Health Survey 2010. Mortality data according to disease and life expectancy were retrieved from the Korean Statistical Information Service. To predict future QALY loss, future population projection data from the Korean Statistical Information Service were used as substitutes for 2010 population size.
  
  
  RESULTS
  Among the assessed 13 NCDs, the largest total QALY loss was for hypertension (513,113 QALYs; units are omitted hereafter), followed by arthritis (509,317) and stroke (431,049). The largest QALY loss due to mortality was stroke (306,733), whereas the largest QALY loss due to morbidity was arthritis (502,513). By applying the middle estimate of future population, the largest increase in total QALY loss between 2010 and 2040 was for hypertension (840,582), followed by stroke (719,076) and diabetes mellitus (474,607).
  
  
  CONCLUSIONS
  Hypertension, arthritis, and stroke are important in terms of total QALY loss, which will continuous to increase because of aging. These results could be used to develop cost-effective interventions that reduce the burden of NCDs.
authors.affiliation: Department of Preventive Medicine, University of Ulsan, Seoul, South Korea.
authors.forename: Minsu
authors.initials: M
authors.lastname: Ock
authors.affiliation: University of Ulsan College of Medicine, Seoul, South Korea.
authors.forename: Jung Won
authors.initials: JW
authors.lastname: Han
authors.affiliation: Public Health Medical Service, Seoul National University, Boramae Medical Center, Seoul, South Korea.
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Department of Nursing, College of Health Science, Dankook University, Cheonan, South Korea.
authors.forename: Seon-Ha
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Preventive Medicine, University of Ulsan, Seoul, South Korea. Electronic address: mdjominwoo@gmail.com.
authors.forename: Min-Woo
authors.initials: MW
authors.lastname: Jo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People / Q000208:ethnology*; D003430:Cross-Sectional Studies; D005260:Female; D005544:Forecasting; D006306:Health Surveys / Q000639:trends*; D006801:Humans; D008017:Life Expectancy / Q000208:ethnology* / Q000639:trends*; D008297:Male; D008875:Middle Aged; D019057:Quality-Adjusted Life Years; D056910:Republic of Korea / Q000208:ethnology; D055815:Young Adult
keywords: chronic disease; health-related quality of life; noncommunicable diseases; quality-adjusted life-year