title: Electrolyte and Haemogram changes post large volume liposuction comparing two different tumescent solutions.
abstract: BACKGROUND
  The most common definitions of large volume liposuction refer to total 5 l volume aspiration during a single procedure (fat plus wetting solution). Profound haemodynamic and metabolic alterations can accompany large volume liposuction. Due to paucity of literature on the effect of different tumescent solutions on the electrolyte balance and haematological changes during large volume liposuction, we carried out this study using two different wetting solutions to study the same.
  
  
  METHODS
  Total 30 patients presenting with varying degrees of localized lipodystrophy in different body regions were enrolled for the study. Prospective randomized controlled trial was conducted by Department of Plastic and Cosmetic Surgery, Sir Ganga Ram Hospital, New Delhi from January 2011 to June 2012. Patients were randomized into two groups of 15 patients each by using computer generated random numbers. Tumescent formula used for Group A (normal saline [NS]) was our modification of Klein's Formula and Tumescent formula used for Group B (ringer lactate [RL]) was our modification of Hunstadt's formula. Serum electrolytes and hematocrit levels were done at preinduction, immediate postoperative period and postoperative day 1.
  
  
  RESULTS
  Statistical analysis was performed using SPSS software version 15.0. Which showed statistically significant electrolytes and hematocrit changes occur during large volume liposuction.
  
  
  CONCLUSIONS
  Statistically significant electrolytes and hematocrit changes occur during large volume liposuction and patients should be kept under observation of anaesthesist for at least 24 h. Patients require strict monitoring of vital parameters and usually Intensive Care Unit is not required. There was no statistical difference in the electrolyte changes using NS or RL as tumescent solution and both solutions were found safe for large volume liposuction.
authors.affiliation: Department of Plastic Surgery, Sir Ganga Ram Hospital, New Delhi, India.
authors.forename: Kumar
authors.initials: K
authors.lastname: Vivek
authors.affiliation: Department of Plastic Surgery, Sir Ganga Ram Hospital, New Delhi, India.
authors.forename: Shah
authors.initials: S
authors.lastname: Amiti
authors.affiliation: Department of Plastic Surgery, Sir Ganga Ram Hospital, New Delhi, India.
authors.forename: Saha
authors.initials: S
authors.lastname: Shivshankar
authors.affiliation: Department of Plastic Surgery, Sir Ganga Ram Hospital, New Delhi, India.
authors.forename: Choudhary
authors.initials: C
authors.lastname: Lalit
keywords: Electrolyte changes during liposuction; haemogram changes during liposuction; large volume liposuction