title: Clinical Features of Ocular Toxocariasis in Adult Korean Patients.
abstract: OBJECTIVE
  To investigate the clinical characteristics and treatment results of adult patients with ocular toxocariasis.
  
  
  METHODS
  A total of 54 consecutive patients who were clinically and serologically diagnosed with ocular toxocariasis were retrospectively reviewed.
  
  
  RESULTS
  Among patients, 66.7 and 77.3% showed increases in eosinophil cationic protein (ECP) and total Ig E in serum, respectively. Four eyes (7.2%) initially presented as neuroretinitis with subsequent motile retinal lesion. The recurrence rates in the combination treatment group with albendazole and corticosteroids were significantly lower than those in the steroid-alone group during the mean follow-up of 27.6 months (p = 0.001).
  
  
  CONCLUSIONS
  The adjunctive test of serum total IgE level may be helpful for the diagnosis of ocular toxocariasis. Ocular toxocariasis should be considered in the differential diagnosis of unilateral neuroretinitis with subsequent motile retinal lesion. Combined treatment with albendazole and corticosteroids appeared to be effective for reducing the recurrence of intraocular inflammation.
authors.affiliation: a Department of Ophthalmology , St. Vincent's Hospital, College of Medicine, The Catholic University of Korea , Suwon , Gyeonggi-do , Korea .
authors.forename: Donghyun
authors.initials: D
authors.lastname: Jee
authors.affiliation: b Department of Ophthalmology , Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea , Seoul , Korea .
authors.forename: Kyu Seop
authors.initials: KS
authors.lastname: Kim
authors.affiliation: b Department of Ophthalmology , Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea , Seoul , Korea .
authors.forename: Won Ki
authors.initials: WK
authors.lastname: Lee
authors.affiliation: c St. Mary's Eye Center , Seoul , Korea , and.
authors.forename: Wungjae
authors.initials: W
authors.lastname: Kim
authors.affiliation: d Catholic High Performance Cell Therapy Center; and Department of Medical Lifescience, College of Medicine, The Catholic University of Korea , Seoul , Korea.
authors.forename: Sohee
authors.initials: S
authors.lastname: Jeon
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D004797:Enzyme-Linked Immunosorbent Assay; D047150:Eosinophil Cationic Protein / Q000097:blood; D015822:Eye Infections, Parasitic / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D056910:Republic of Korea; D012173:Retinitis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D012189:Retrospective Studies; D017166:Toxocara canis / Q000276:immunology / Q000302:isolation & purification; D014120:Toxocariasis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D014605:Uveitis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology
chemical_list: D000909:Antibodies, Helminth; D000981:Antiprotozoal Agents; D005938:Glucocorticoids; D007073:Immunoglobulin E; D047150:Eosinophil Cationic Protein; C479220:RNASE3 protein, human; D015766:Albendazole
keywords: Albendazole; neuroretinitis; ocular toxocariasis; toxocariasis; uveitis