title: Gradient-based magnetic resonance electrical properties imaging of brain tissues.
abstract: Electrical properties tomography (EPT) holds promise for noninvasively mapping at high spatial resolution the electrical conductivity and permittivity of biological tissues in vivo using a magnetic resonance imaging (MRI) scanner. In the present study, we have developed a novel gradient-based EPT approach with greatly improved tissue boundary reconstruction and largely elevated robustness against measurement noise compared to existing techniques. Using a 7 Tesla MRI system, we report, for the first time, high-quality in vivo human brain electrical property images with refined structural details, which can potentially merit clinical diagnosis (such as cancer detection) and high-field MRI applications (quantification of local specific absorption rate) in the future.
authors.lastname: Jiaen Liu
authors.lastname: Xiaotong Zhang
authors.forename: Sebastian
authors.initials: S
authors.lastname: Schmitter
authors.forename: Pierre-Francois
authors.initials: PF
authors.lastname: Van de Moortele
authors.lastname: Bin He
mesh_terms: D000465:Algorithms; D001921:Brain / Q000502:physiology*; D004553:Electric Conductivity; D006801:Humans; D008279:Magnetic Resonance Imaging; D059906:Neuroimaging / Q000379:methods*; D019047:Phantoms, Imaging; D014054:Tomography