title: Geriatric patients with known acute kidney injury and normal renal function at the time of admittance to the intensive care unit/assessment of RRT requirement and mortality: retrospective case-control study.
abstract: BACKGROUND
  The objective of our study was to investigate the renal functions on admittance, chronic disease status, the diagnosis on admittance to the intensive care unit (ICU), need for mechanical ventilation and medication groups and their impact over mortality and renal replacement treatment (RRT) requirement in geriatric patients with and without known acute kidney injury (AKI) at the time of admittance.
  
  
  METHODS
  A total of 168 patients over 65 years of age having been monitored for more than 24 h in our Respiratory ICU and were assessed retrospectively. Factors influencing the RRT requirement and the mortality rates of patients with known AKI and normal renal function at the time of admittance were reviewed.
  
  
  RESULTS
  Of 80 patients, 8 (10 %) without AKI at the time of admittance to the ICU required RRT during the follow-up, however, 72 of those (90 %) completed the follow-up without developing AKI. Of 88 patients, 29 (33 %) with AKI at the time of admittance to the ICU required RRT, however, 59 of those (67 %) completed the follow-up without any need for RRT.
  
  
  CONCLUSIONS
  Presence of known AKI in the geriatric population at the time of their admittance to the respiratory ICU remarkably increased both the need for RRT and the mortality with respect to the geriatric population with normal renal functions. After having assessed the reasons justifying RRT and increasing the mortality during the intensive care, gastrointestinal bleeding and hypotension which necessitate the combined use of dopamine and noradrenaline were concluded to be prominent.
authors.affiliation: Department of Chest Disease, Bezmialem Vakif University Medical School, Istanbul, Turkey, fatmanurkarakose@yahoo.com.
authors.forename: Fatmanur
authors.initials: F
authors.lastname: Karakose
authors.forename: Muhammet Emin
authors.initials: ME
authors.lastname: Akkoyunlu
authors.forename: Reha
authors.initials: R
authors.lastname: Erkoc
authors.forename: Abdullah
authors.initials: A
authors.lastname: Kansu
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bayram
authors.forename: Murat
authors.initials: M
authors.lastname: Sezer
authors.forename: Hatice
authors.initials: H
authors.lastname: Ozcelik
authors.forename: Levent
authors.initials: L
authors.lastname: Kart
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy*; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D005260:Female; D015577:Geriatric Assessment / Q000706:statistics & numerical data; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D007677:Kidney Function Tests / Q000706:statistics & numerical data; D008297:Male; D010343:Patient Admission / Q000706:statistics & numerical data; D017582:Renal Replacement Therapy / Q000401:mortality* / Q000706:statistics & numerical data*; D012121:Respiration, Artificial / Q000401:mortality* / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D014421:Turkey / Q000453:epidemiology