title: Expeditious entry to the chamigrane endoperoxide family of natural products.
abstract: Several members of the recently reported peroxy chamigrane family of natural products were synthesized via a distereoselective route with a novel facial-selective epoxidation of a spiroundecadiene, a facile epoxide rearrangement, and a Co(II)-mediated silylperoxidation as the key steps. Adaptation of the diastereoselective route to an enantioselective one is also illustrated.
authors.affiliation: State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors.forename: Hui-Jun
authors.initials: HJ
authors.lastname: Chen
authors.forename: Yikang
authors.initials: Y
authors.lastname: Wu
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010545:Peroxides / Q000138:chemical synthesis* / Q000737:chemistry; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D013237:Stereoisomerism; D032901:Talaromyces / Q000737:chemistry
chemical_list: D001688:Biological Products; D010545:Peroxides; D012717:Sesquiterpenes