title: Injury of the corticoreticular pathway in subarachnoid haemorrhage after rupture of a cerebral artery aneurysm.
abstract: OBJECTIVE
  Several studies have reported on injury of the corticoreticular pathway in patients with stroke and traumatic brain injury. However, little is known about injury of the corticoreticular pathway in patients with subarachnoid haemorrhage. The aim of the current study was to investigate corticoreticular pathway injury in patients with subarachnoid haemorrhage.
  
  
  METHODS
  Comparative study.
  
  
  METHODS
  Among 137 patients with subarachnoid haemorrhage, 17 patients with motor weakness who showed intact integrity of the corticospinal tract were recruited.
  
  
  METHODS
  Motricity Index was used for measurement of motor function. The fractional anisotropy value, apparent diffusion coefficient value, fibre volume, and integrity of the corticoreticular pathway were used for the diffusion tensor imaging parameters.
  
  
  RESULTS
  Twelve (70.6%) of 17 patients and 18 (52.9%) of 34 hemispheres showed a discontinuation of the corticoreticular pathway at the midbrain level. The contralateral shoulder, hip, and lower extremity of the discontinued corticoreticular pathway showed lower motor functions, in comparison with those of the contralateral side of the intact corticoreticular pathway (p < 0.05). By contrast, the Motricity Index for distal joint, upper and total Motricity Index were not different irrespective of the state of the corticoreticular pathway (p > 0.05).
  
  
  CONCLUSIONS
  Corticoreticular pathway injury is common in patients with motor weakness after subarachnoid haemorrhage, and it appears to be related to weakness in the contralateral shoulder, hip and lower extremity.
authors.affiliation: Department of Physical Medicine and Rehabilitation, , College of Medicine, Yeungnam University , Seoul, Republic of Korea.
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Jang
authors.forename: Byung Yeon
authors.initials: BY
authors.lastname: Choi
authors.forename: Seong Ho
authors.initials: SH
authors.lastname: Kim
authors.forename: Chul Hoon
authors.initials: CH
authors.lastname: Chang
authors.forename: Young Jin
authors.initials: YJ
authors.lastname: Jung
authors.forename: Sang Seok
authors.initials: SS
authors.lastname: Yeo
mesh_terms: D000328:Adult; D000368:Aged; D016880:Anisotropy; D056324:Diffusion Tensor Imaging; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D011712:Pyramidal Tracts / Q000503:physiopathology*; D012422:Rupture, Spontaneous; D013345:Subarachnoid Hemorrhage / Q000209:etiology / Q000503:physiopathology*