title: Poly(3,4-ethylenedioxythiophene)/graphene oxide composite coating for electrode-tissue interface.
abstract: Owing to interacting with the living tissue directly, the electrode-tissue interface largely determines the performance of the whole bioelectronics devices. The miniaturization of biomedical electronic components requires interface materials to possess properties including excellent electrical performance, good biocompatibility and compatibility with microelectronic fabrication process. Considering the unique characteristics and wide applications in biomedical domain of conducting polymer and graphene, composite film consists of poly(3,4-ethylenedioxythiophene) (PEDOT) and graphene oxide (GO) is proposed as electrode-tissue interface in this work. The facilely electrochemically synthesized PEDOT/GO coating on microelectrodes shows low impedance, high charge storage capacity and good biocompatibility to act as electrode-tissue interface. As a result, the composite film is a potential biomaterial as electrode-tissue interface for tissue engineering and further implantable electrophysiological devices.
authors.forename: Hong-Chang
authors.initials: HC
authors.lastname: Tian
authors.forename: Jing-Quan
authors.initials: JQ
authors.lastname: Liu
authors.forename: Xiao-Yang
authors.initials: XY
authors.lastname: Kang
authors.forename: Dai-Xu
authors.initials: DX
authors.lastname: Wei
authors.forename: Chuan
authors.initials: C
authors.lastname: Zhang
authors.forename: Jing-Cheng
authors.initials: JC
authors.lastname: Du
authors.forename: Bin
authors.initials: B
authors.lastname: Yang
authors.forename: Xiang
authors.initials: X
authors.lastname: Chen
authors.forename: Chun-Sheng
authors.initials: CS
authors.lastname: Yang
mesh_terms: D000818:Animals; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry*; D048430:Cell Shape; D058266:Dielectric Spectroscopy; D004566:Electrodes; D006108:Graphite / Q000737:chemistry*; D051379:Mice; D041681:NIH 3T3 Cells; D010087:Oxides / Q000737:chemistry*; D016716:PC12 Cells; D011108:Polymers / Q000737:chemistry*; D011817:Rabbits; D051381:Rats; D013056:Spectrophotometry, Ultraviolet; D023822:Tissue Engineering
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D010087:Oxides; D011108:Polymers; C121383:poly(3,4-ethylene dioxythiophene); D006108:Graphite