title: Radiofrequency ablation of drug-resistant cancer cells using molecularly targeted carboxyl-functionalized biodegradable graphene.
abstract: Under ultralow radiofrequency (RF) power, transferrin-conjugated graphene nanoparticles can thermally ablate drug- or radiation-resistant cancer cells very effectively. The results suggest that graphene-based RF hyperthermia can be an efficient method to manage drug-/radiation-resistant cancers.
authors.affiliation: Amrita Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham University, Cochin, 682 041, Kerala, India.
authors.forename: Abhilash
authors.initials: A
authors.lastname: Sasidharan
authors.forename: Amal J
authors.initials: AJ
authors.lastname: Sivaram
authors.forename: Archana P
authors.initials: AP
authors.lastname: Retnakumari
authors.forename: Parwathy
authors.initials: P
authors.lastname: Chandran
authors.forename: Giridharan Loghanathan
authors.initials: GL
authors.lastname: Malarvizhi
authors.forename: Shantikumar
authors.initials: S
authors.lastname: Nair
authors.forename: Manzoor
authors.initials: M
authors.lastname: Koyakutty
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D001672:Biocompatible Materials / Q000737:chemistry / Q000494:pharmacology*; D017115:Catheter Ablation; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects* / Q000528:radiation effects*; D019008:Drug Resistance, Neoplasm; D006108:Graphite / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D018613:Microscopy, Confocal; D011846:Radio Waves
chemical_list: D000970:Antineoplastic Agents; D001672:Biocompatible Materials; D006108:Graphite
keywords: cancer therapy; drug resistance; graphene; radiofrequency ablation; transferrin