title: Invasive maxillary sinus aspergillosis: A case report successfully treated with voriconazole and surgical debridement.
abstract: BACKGROUND
  Invasive aspergillosis of the paranasal sinuses is a rare disease and often misdiagnosed; however, its incidence has seen substancial growth over the past 2 decades. Definitive diagnosis of these lesions is based on histological examination and fungal culture.
  
  
  METHODS
  An 81-year-old woman with a history of pain in the left maxillary region is presented. The diagnosis was invasive maxillary aspergillosis in immunocompetent patient, which was successfully treated with voriconazole and surgical debridement. Possible clinical manifestations, diagnostic imaging techniques and treatment used are discussed. Since the introduction of voriconazole, there have been several reports of patients with invasive aspergillosis who responded to treatment with this new antifungal agent.
  
  
  CONCLUSIONS
  We report the importance of early diagnosis and selection of an appropriate antifungal agent to achieve a successful treatment. Key words:Invasive aspergillosis, voriconazole, fungal sinusitis, antifungal agent, open sinus surgery.
authors.affiliation: Department of Oral and Maxillofacial Surgery. Río Hortega Hospital, Valladolid, Spain.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Peral-Cagigal
authors.affiliation: Department of Oral and Maxillofacial Surgery. Río Hortega Hospital, Valladolid, Spain.
authors.forename: Luis-Miguel
authors.initials: LM
authors.lastname: Redondo-González
authors.affiliation: Department of Oral and Maxillofacial Surgery. Río Hortega Hospital, Valladolid, Spain.
authors.forename: Alberto
authors.initials: A
authors.lastname: Verrier-Hernández