title: [Study on risk factors of hepatitis C virus infection among Han population in Henan province].
abstract: OBJECTIVE
  To study the risk factors of hepatitis C Virus Infection among Han population in Henan Province, providing evidence for the development of targeted prevention and control measures.
  
  
  METHODS
  In this 1: 1 matched case-control study, data of 134 cases and 134 controls were collected in seven hospitals from June 2013 to September 2013. Case group with the following conditions: Han nationality, first diagnosed hepatitis C in 2013, Current address and investigation belong to the same district (county), above 18 years old; with the following conditions can't into case group: not to cooperate with the investigation, late-stage Hepatitis C patients. Control group with the following conditions: Han nationality, with the matched case patients the same gender, in the same hospital for treatment , from the same district (county), the age difference ≤ 5 years old and in the same age group. With the following conditions can't into control group:not to cooperate with the investigation, diagnosed with hepatitis B, hepatitis C patients. Collect 3 ml blood samples to test anti-HCV. Single factors were analyzed with χ(2) between case and control, risk factors were analyzed with logistic regression model.
  
  
  RESULTS
  The ratio about blood donation, blood transfusion, operation and acupuncture of cases were 35.1% (47/134), 27.6% (37/134), 42.5% (57/134), 12.7% (17/134), with differences compared to those of controls (2.2% (3/134), 5.2% (7/134), 21.6% (29/134), 5.2% (7/134))(χ(2) values were 47.60, 24.47, 13.42 and 4.58, all P values <0.05). Compared with those never received blood transfusion and those never donated blood, former blood receptors and blood donors had higher risk of hepatitis C infection(OR: 2.01, 95%CI:1.32-3.05; OR:2.68, 95%CI:1.85-3.88).
  
  
  RESULTS
  of multiple nonconditional logistic regression analysis showed that Plasma donors and whole blood donors had higher risk of hepatitis C infection than those never donated plasma and blood (OR:76.71, 95%CI: 10.25-574.25; OR:10.23, 95%CI: 2.15-48.70).
  
  
  CONCLUSIONS
  Blood transfusion and abnormal blood are independent risk factors among Han population in Henan Province of hepatitis C infection. The Plasma donors, blood donors and with the increase in the times of blood transfusion, the risk of hepatitis C infection is increase.
authors.affiliation: Institute for Prevention and Control of STD and AIDS , Henan Provincial Center for Diseases Control and Prevention,Zhengzhou 450016, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.affiliation: Institute for Prevention and Control of STD and AIDS , Henan Provincial Center for Diseases Control and Prevention, Zhengzhou 450016, China.
authors.forename: Yanmin
authors.initials: Y
authors.lastname: Ma
authors.affiliation: Institute for Prevention and Control of STD and AIDS , Henan Provincial Center for Diseases Control and Prevention, Zhengzhou 450016, China.
authors.forename: Wenjie
authors.initials: W
authors.lastname: Yang
authors.affiliation: Institute for Prevention and Control of STD and AIDS , Henan Provincial Center for Diseases Control and Prevention, Zhengzhou 450016, China.
authors.forename: Dingyong
authors.initials: D
authors.lastname: Sun
authors.affiliation: Institute for Prevention and Control of STD and AIDS , Henan Provincial Center for Diseases Control and Prevention, Zhengzhou 450016, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhu
authors.affiliation: Institute for Prevention and Control of STD and AIDS , Henan Provincial Center for Diseases Control and Prevention, Zhengzhou 450016, China. Email: wangzhe@hncdc.com.cn.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Wang
mesh_terms: D000368:Aged; D001782:Blood Donors; D001803:Blood Transfusion; D016022:Case-Control Studies; D002681:China / Q000208:ethnology; D016174:Hepacivirus; D006526:Hepatitis C; D006801:Humans; D012307:Risk Factors