title: Fusion of structural and functional cardiac magnetic resonance imaging data for studying ventricular fibrillation.
abstract: Magnetic Resonance Imaging (MRI) techniques such as Current Density Imaging (CDI) and Diffusion Tensor Imaging (DTI) provide a complementing set of imaging data that can describe both the functional and structural states of biological tissues. This paper presents a Joint Independent Component Analysis (jICA) based fusion approach which can be utilized to fuse CDI and DTI data to quantify the differences between two cardiac states: Ventricular Fibrillation (VF) and Asystolic/Normal (AS/NM). Such an approach could lead to a better insight on the mechanism of VF. Fusing CDI and DTI data from 8 data sets from 6 beating porcine hearts, in effect, detects the differences between two cardiac states, qualitatively and quantitatively. This initial study demonstrates the applicability of MRI-based imaging techniques and jICA-based fusion approach in studying cardiac arrhythmias.
authors.forename: K
authors.initials: K
authors.lastname: Magtibay
authors.forename: M
authors.initials: M
authors.lastname: Beheshti
authors.forename: F H
authors.initials: FH
authors.lastname: Foomany
authors.forename: K
authors.initials: K
authors.lastname: Balasundaram
authors.forename: S
authors.initials: S
authors.lastname: Masse
authors.forename: P
authors.initials: P
authors.lastname: Lai
authors.forename: J
authors.initials: J
authors.lastname: Asta
authors.forename: N
authors.initials: N
authors.lastname: Zamiri
authors.forename: D A
authors.initials: DA
authors.lastname: Jaffray
authors.forename: K
authors.initials: K
authors.lastname: Nanthakumar
authors.forename: S
authors.initials: S
authors.lastname: Krishnan
authors.forename: K
authors.initials: K
authors.lastname: Umapathy
mesh_terms: D000465:Algorithms; D000818:Animals; D056324:Diffusion Tensor Imaging; D006321:Heart / Q000503:physiopathology*; D066298:In Vitro Techniques; D008279:Magnetic Resonance Imaging / Q000379:methods*; D034421:Sus scrofa; D014693:Ventricular Fibrillation / Q000473:pathology* / Q000503:physiopathology*