title: Tandem catalytic oxidative deacetylation of acetoacetic esters and heteroaromatic cyclizations.
abstract: One pot syntheses of furan, thiophene, and pyrrole were accomplished by oxidative deacetylation using Mn(III)/Co(II) catalysts and the Paal-Knorr reaction from 1,5-dicarbonyl compounds, which are prepared from the conjugate addition of ethyl acetoacetate to α,β-unsaturated carbonyl compounds. The oxidative deacetylation and reductive cyclization of β-ketoesters derived from ethyl acetoacetate and o-nitrobenzyl bromides efficiently produced diversely substituted indoles.
authors.affiliation: School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai, 200237, China.
authors.forename: Yeming
authors.initials: Y
authors.lastname: Ju
authors.forename: Di
authors.initials: D
authors.lastname: Miao
authors.forename: Ruiyang
authors.initials: R
authors.lastname: Yu
authors.forename: Sangho
authors.initials: S
authors.lastname: Koo
mesh_terms: D000090:Acetoacetates / Q000737:chemistry*; D000107:Acetylation; D002384:Catalysis; D003500:Cyclization; D004952:Esters / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D000090:Acetoacetates; D004952:Esters; D006841:Hydrocarbons, Aromatic; D009942:Organometallic Compounds