title: The association of lifetime insight and cognition in psychosis.
abstract: Poor insight has been related to poor course in psychosis. However, the role of cognition in insight remains unclear. The aim of this study was to examine the influence of cognition and lifetime psychopathological dimensions on insight in psychosis. We followed up 42 patients with psychotic disorders over 10years. Lifetime psychopathological dimensions and cognitive performance were assessed. Patients were divided into two groups by lifetime patterns of insight and compared with 42 healthy volunteers. Lower IQ and poorer social cognition were associated with higher risks of poorer lifetime insight of feeling ill and global insight respectively. Lifetime negative symptoms were associated with a higher risk of poorer lifetime insight into symptoms. Lifetime lack of insight is independent of cognitive impairment in specific domains, except for social cognition. Higher IQ may contribute to better lifetime awareness of illness, while better ability to manage emotions is involved in lifetime global insight.
authors.affiliation: Psychiatric Unit B, Complejo Hospitalario de Navarra, Pamplona Spain; Department of Basic Psychology I, Faculty of Psychology, National Distance Education University (UNED), Madrid Spain.
authors.forename: Ana M
authors.initials: AM
authors.lastname: Sánchez-Torres
authors.affiliation: Psychiatric Unit B, Complejo Hospitalario de Navarra, Pamplona Spain.
authors.forename: Amalia
authors.initials: A
authors.lastname: Zarzuela
authors.affiliation: Psychiatric Unit B, Complejo Hospitalario de Navarra, Pamplona Spain.
authors.forename: Victor
authors.initials: V
authors.lastname: Peralta
authors.affiliation: Psychiatric Unit B, Complejo Hospitalario de Navarra, Pamplona Spain. Electronic address: mcuestaz@cfnavarra.es.
authors.forename: Manuel J
authors.initials: MJ
authors.lastname: Cuesta
mesh_terms: D000328:Adult; D001364:Awareness; D003071:Cognition; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007360:Intelligence; D008297:Male; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000523:psychology*; D012938:Social Perception
keywords: Cognition; Lifetime insight; Psychopathology; Psychosis