title: New therapies in non-Hodgkin lymphoma.
abstract: Non-Hodgkin lymphomas are among the most prevalent hematologic malignancies. Although the addition of rituximab (R) to chemotherapy has made a big impact in the treatment of B cell lymphomas, most of them are not cured yet. The panorama in natural killer/T cell lymphomas is more unsatisfactory, thus representing a group of diseases where effective therapies constitute an urgent medical need. In recent years, several new antineoplastic agents have been tested in clinical trials showing promising results. The aim of this review is to update information of these studies that are already changing the scenario of the treatment of patients with Non-Hodgkin lymphoma.
authors.affiliation: Hematology Service, Hospital de la Santa Creu i Sant Pau, Carrer Mas Casanovas, 90, 08041 Barcelona, Spain.
authors.forename: Silvana
authors.initials: S
authors.lastname: Novelli
authors.forename: Jorge
authors.initials: J
authors.lastname: Sierra
authors.forename: Javier
authors.initials: J
authors.lastname: Briones
mesh_terms: D058846:Antibodies, Monoclonal, Murine-Derived / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D015195:Drug Design; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy* / Q000473:pathology; D000069283:Rituximab
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D000069283:Rituximab
keywords: B cell receptor; NF-κB inhibitors; antibodies; lymphoma; non-Hodgkin lymphoma; treatment