title: Diffuse correlation spectroscopy for measurement of cerebral blood flow: future prospects.
abstract: Diffuse correlation spectroscopy (DCS) is an emerging optical modality used to measure cortical cerebral blood flow. This outlook presents a brief overview of the technology, summarizing the advantages and limitations of the method, and describing its recent applications to animal, adult, and infant cohorts. At last, the paper highlights future applications where DCS may play a pivotal role individualizing patient management and enhancing our understanding of neurovascular coupling, activation, and brain development.
authors.affiliation: Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Charlestown, Massachusetts 02129.
authors.forename: Erin M
authors.initials: EM
authors.lastname: Buckley
authors.affiliation: University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania 19104.
authors.forename: Ashwin B
authors.initials: AB
authors.lastname: Parthasarathy
authors.affiliation: Boston Children's Hospital, Fetal-Neonatal Neuroimaging and Developmental Science Center, Boston, Massachusetts 02115.
authors.forename: P Ellen
authors.initials: PE
authors.lastname: Grant
authors.affiliation: University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania 19104.
authors.forename: Arjun G
authors.initials: AG
authors.lastname: Yodh
authors.affiliation: Massachusetts General Hospital, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Charlestown, Massachusetts 02129.
authors.forename: Maria Angela
authors.initials: MA
authors.lastname: Franceschini
keywords: biomedical optics; cerebral blood flow; medical imaging; spectroscopy