title: The use of serum uric acid concentration as an indicator of laparoscopic sleeve gastrectomy success.
abstract: Laparoscopic sleeve gastrectomy (LSG) effectively reduces weight by restricting gastric capacity and altering gut hormones levels. We designed a prospective study to investigate the correlation of serum uric acid (SUA) concentration and weight loss. SUA and body mass index (BMI) were measured preoperatively and on first postoperative month and year in patients who underwent LSG in our department of bariatric surgery. Data on 55 patients were analyzed. Preoperative SUA concentration had a significant positive correlation with percentage of total weight loss (TWL) on first postoperative month (P = 0.001) and year (P = 0.002). SUA concentration on first postoperative month had a positive correlation with percentage of TWL on first postoperative year (P = 0.004). SUA concentration could be used as a predictor of LSG's success and could help in early detection of patients with rapid loss of weight, in order to prevent complications.
authors.affiliation: 1st Propaedeutic Surgical Department, "Hippokration" General Hospital of Athens, Medical School of Athens, National and Kapodistrian University of Athens, Greece.
authors.forename: Evangelos
authors.initials: E
authors.lastname: Menenakos
authors.forename: Georgia
authors.initials: G
authors.lastname: Doulami
authors.forename: Irene P
authors.initials: IP
authors.lastname: Tzanetakou
authors.forename: Maria
authors.initials: M
authors.lastname: Natoudi
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Kokoroskos
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Almpanopoulos
authors.forename: Emmanouil
authors.initials: E
authors.lastname: Leandros
authors.forename: George
authors.initials: G
authors.lastname: Zografos
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Theodorou
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000379:methods; D006801:Humans; D033461:Hyperuricemia / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000097:blood / Q000150:complications / Q000601:surgery*; D011184:Postoperative Period; D011446:Prospective Studies; D016896:Treatment Outcome; D014527:Uric Acid / Q000097:blood*; D015431:Weight Loss; D055815:Young Adult
chemical_list: D015415:Biomarkers; D014527:Uric Acid
keywords: Bariatric surgery; Metabolic syndrome; Uric acid; Weight loss