title: Comparison of compliance of adjuvant chemotherapy between laparoscopic and open surgery in patients with colon cancer.
abstract: OBJECTIVE
  Many studies have shown that the completion of adjuvant chemotherapy improves the survival rate. Recently, laparoscopic surgery has been used to treat patients with colon cancer. We analyzed the relationship between the completion of adjuvant chemotherapy and the operation method.
  
  
  METHODS
  We retrospectively analyzed the medical records of 147 patients diagnosed with colon cancer from January 1, 2009, to May 31, 2012. The numbers of patients who underwent laparoscopic and open surgery were 91 and 56, respectively. We analyzed the relationship between the operation method and various factors such as the completion rate of chemotherapy, the patient's age, gender, and physical activity, the postoperative hospital stay, the start time of chemotherapy, and the patient's body mass index (BMI), TNM stage, and type of health insurance.
  
  
  RESULTS
  In the laparoscopic surgery group, the postoperative hospital stay (13.5 ± 14.82 days vs. 19.6 ± 11.38 days, P = 0.001) and start time of chemotherapy (17.7 ± 17.48 days vs. 23.0 ± 15.00 days, P = 0.044) were shorter, but the percent complete of chemotherapy (71/91 [78.0%] vs. 38/56 [67.8%], P = 0.121), and survival rate (88/91 [96.7%], 47/56 [83.9%], P = 0.007) were higher than they were in the open surgery group. Patients who were elderly, had a low BMI, and a high American Society of Anesthesiologists score were less likely to complete adjuvant chemotherapy than other patients were.
  
  
  CONCLUSIONS
  Laparoscopic surgery shows a shorter postoperative hospital stay, a shorter start time of chemotherapy, and a higher survival rate. Laparoscopic surgery may be expected to increase compliance of chemotherapy and to improve survival rate.
authors.affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.
authors.forename: Kan Ho
authors.initials: KH
authors.lastname: Chun
authors.affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.
authors.forename: Byung Noe
authors.initials: BN
authors.lastname: Bae
authors.affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.
authors.forename: Hoon
authors.initials: H
authors.lastname: An
authors.affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.
authors.forename: Hyeonseok
authors.initials: H
authors.lastname: Jeong
authors.affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.
authors.forename: Hyunjin
authors.initials: H
authors.lastname: Cho
authors.affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.
authors.forename: Geumhee
authors.initials: G
authors.lastname: Gwak
authors.affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.
authors.forename: Keun Ho
authors.initials: KH
authors.lastname: Yang
authors.affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.
authors.forename: Ki Hwan
authors.initials: KH
authors.lastname: Kim
authors.affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.
authors.forename: Hong Ju
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Surgery, Inje University Sanggye Paik Hospital, Seoul, Korea.
authors.forename: Young Duk
authors.initials: YD
authors.lastname: Kim
keywords: Adjuvant chemotherapy; Colon neoplasms; Laparoscopy; Percent complete