title: Two new macrosporin dimers from the fungus Alternaria sp. XZSBG-1.
abstract: Two new macrosporin dimers (1-2) along with four known compounds (3-6) were isolated from the extracts of the fungal strain Alternaria sp. XZSBG-1 from the sediment of the salt lake in the Bange, Tibetan, China. Their structures were determined by spectroscopic methods, mainly by 2D NMR spectra. Compounds 1 and 2 are new macrosporin dimers with symmetric chemical structures. In the cytotoxicity assay and inhibited alpha-glucosidase activity assay, all these compounds showed no notable inhibitory activity.
authors.affiliation: a School of Chemistry and Chemical Engineering, Sun Yat-sen University , No. 135, West Xingang Road, Guangzhou 510275 , P.R. China.
authors.forename: Bin
authors.initials: B
authors.lastname: Chen
authors.forename: Lan
authors.initials: L
authors.lastname: Liu
authors.forename: Xun
authors.initials: X
authors.lastname: Zhu
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Yi
authors.initials: Y
authors.lastname: Long
authors.forename: Si-Ping
authors.initials: SP
authors.lastname: Jiang
authors.forename: Ai-Guo
authors.initials: AG
authors.lastname: Xu
authors.forename: Yong-Cheng
authors.initials: YC
authors.lastname: Lin
mesh_terms: D000528:Alternaria / Q000737:chemistry*; D000880:Anthraquinones / Q000737:chemistry*; D045744:Cell Line, Tumor; D002681:China; D005285:Fermentation; D019015:Geologic Sediments / Q000382:microbiology; D006801:Humans; D007783:Lactones / Q000737:chemistry; D060106:Lakes / Q000382:microbiology; D015394:Molecular Structure; D000520:alpha-Glucosidases
chemical_list: D000880:Anthraquinones; D007783:Lactones; C058810:macrosporin; D000520:alpha-Glucosidases; C005197:alternariol
keywords: Alternaria sp; macrosporin dimers; structure elucidation