title: [Application of silk fibroin scaffold in bone tissue engineering].
abstract: OBJECTIVE
  To review the application of silk fibroin scaffold in bone tissue engineering.
  
  
  METHODS
  The related literature about the application of silk fibroin scaffold in bone tissue engineering was reviewed, analyzed, and summarized.
  
  
  RESULTS
  Silk fibroin can be manufactured into many types, such as hydrogel, film, nano-fiber, and three-dimensional scaffold, which have superior biocompatibility, slow biodegradability, nontoxic degradation products, and excellent mechanical strength. Meanwhile these silk fibroin biomaterials can be chemically modified and can be used to carry stem cells, growth factors, and compound inorganic matter.
  
  
  CONCLUSIONS
  Silk fibroin scaffolds can be widely used in bone tissue engineering. But it still needs further study to prepare the scaffold in accordance with the requirement of tissue engineering.
authors.affiliation: Medical School of Chinese PLA, Beijing, P.R. China.
authors.forename: Shijun
authors.initials: S
authors.lastname: Lu
authors.forename: Baoqi
authors.initials: B
authors.lastname: Zuo
authors.forename: Hongchen
authors.initials: H
authors.lastname: Liu
mesh_terms: D001672:Biocompatible Materials; D018929:Cell Culture Techniques / Q000379:methods; D005349:Fibroins / Q000737:chemistry*; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds
chemical_list: D001672:Biocompatible Materials; D005349:Fibroins