title: Diagnostic value of core needle biopsy and fine-needle aspiration in salivary gland lesions.
abstract: Core needle biopsy (CNB) has gained acceptance as a minimally invasive procedure in the head and neck. Nevertheless, many concerns arise regarding the value and safety of this method in the assessment of salivary gland lesions.
  
  
  
  This prospective study comprises 111 patients with a salivary gland lesion. The results of ultrasound-guided CNB were compared with those of fine-needle aspiration (FNA) in the 103 histologically verified cases.
  
  
  
  CNB achieved a higher accuracy than FNA in identifying true neoplasms (98% vs 91%) and detecting malignancy (99% vs 87%), and was also superior to FNA providing a specific diagnosis (93% vs 74%). In both methods, no complications, such as bleeding, infection, nerve injury, or tumor-cell seeding, occurred.
  
  
  
  CNB is a simple, safe, and highly accurate procedure, which should be considered as an additional diagnostic tool in the assessment of salivary gland lesions. © 2015 Wiley Periodicals, Inc. Head Neck 38: E346-E352, 2016.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital AG, Aarau, Switzerland.
authors.forename: Eva
authors.initials: E
authors.lastname: Novoa
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Basel, Basel, Switzerland.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Gürtler
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital AG, Aarau, Switzerland.
authors.forename: André
authors.initials: A
authors.lastname: Arnoux
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital Baselland, Liestal, Switzerland.
authors.forename: Marcel
authors.initials: M
authors.lastname: Kraft
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D062005:Biopsy, Large-Core Needle; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012469:Salivary Glands / Q000473:pathology*; D012680:Sensitivity and Specificity; D055815:Young Adult
keywords: core needle biopsy; fine-needle aspiration; salivary gland; tumor-cell seeding; ultrasound