title: Surgical adhesive BioGlue™ does not benefit tendon repair strength: an ex vivo study.
abstract: Surgical adhesives are useful supplements in surgery, but their benefit in tendon repair is uncertain. The purpose of this study was to evaluate the effect of BioGlue™ on strength of flexor tendon repair. A total of 60 porcine flexor tendons were divided into three groups. In group one, a conventional core and peripheral suture repair was used. In group two, a core suture and BioGlue™ were used. In group three, a conventional core and peripheral suture repair and BioGlue™ were used. We performed static and cyclic axial load testing and measured diameter of the repair site. We found that BioGlue™ did not improve the tensile strength when added to a core and peripheral suture and that there was an increase in bulk at the repair site. We conclude that BioGlue™ application cannot replace a peripheral suture as tensile strength significantly decreases without a peripheral suture, and it does not benefit a tendon already repaired with a core and peripheral suture.
  
  
  METHODS
  n/a.
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Clinics of Wuerzburg, Wuerzburg, Germany Jordan_M@ukw.de.
authors.forename: M C
authors.initials: MC
authors.lastname: Jordan
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Clinics of Wuerzburg, Wuerzburg, Germany.
authors.forename: V
authors.initials: V
authors.lastname: Schmitt
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Clinics of Wuerzburg, Wuerzburg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Dannigkeit
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Clinics of Wuerzburg, Wuerzburg, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Schmidt
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Clinics of Wuerzburg, Wuerzburg, Germany.
authors.forename: R H
authors.initials: RH
authors.lastname: Meffert
authors.affiliation: Department of Trauma, Hand, Plastic and Reconstructive Surgery, University Clinics of Wuerzburg, Wuerzburg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Hoelscher-Doht
mesh_terms: D000818:Animals; D023421:Models, Animal; D011506:Proteins; D013536:Suture Techniques; D013552:Swine; D013708:Tendon Injuries / Q000601:surgery*; D013710:Tendons / Q000601:surgery*; D013718:Tensile Strength; D014014:Tissue Adhesives
chemical_list: C472676:Bio-glue; D011506:Proteins; D014014:Tissue Adhesives
keywords: Augmentation; BioGlue; fibrin glue; flexor tendon repair; gluing; surgical adhesive; suture; tendon