title: A multiplex fluorophore molecular beacon: detection of the target sequence using large Stokes shift and multiple emission signal properties.
abstract: We have developed a multiplex fluorophore molecular beacon () with fluorophores located at its end to produce unique FRET (Fluorescence Resonance Energy Transfer). It exhibited diverse fluorescence properties depending on the mixing pattern, such as large Stokes shift emission and multiple colors, namely, blue, green and red using one excitation wavelength. Our also worked in probing a target perfect matched sequence with exonuclease III.
authors.affiliation: Department of Chemistry, Chonbuk National University, Jeonju 561-756, South Korea. yseo@jbnu.ac.kr.
authors.forename: Han Na
authors.initials: HN
authors.lastname: Joo
authors.forename: Young Jun
authors.initials: YJ
authors.lastname: Seo
mesh_terms: D015195:Drug Design; D005456:Fluorescent Dyes / Q000737:chemistry*; D015345:Oligonucleotide Probes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D015345:Oligonucleotide Probes