title: The Impact of Dietary Interventions on the Symptoms of Inflammatory Bowel Disease: A Systematic Review.
abstract: Diet may be a successful part of the treatment plan for improving outcome in patients with inflammatory bowel disease (IBD). This study aimed to systematically review all published clinical trials evaluating the effects of a regular diet on symptoms of IBD. Three medical databases were searched for clinical trials evaluating an intervention that involved dietary manipulation using a regular diet on adults with IBD whose symptoms were objectively measured before and after the intervention. The most common types of regular diet interventions that we observed in the literature fell into the following three categories: low residue/low fiber diets, exclusion diets, or other specific diets. Of all included studies, the few that were of higher quality and that observed a statistically significant improvement in symptoms in the diet group compared to the control group fell under the exclusion diet group or the other specific diet group. We were able to identify several high quality clinical trials evaluating dietary manipulations on symptoms of IBD. Exclusion diets and the low FODMAP diet are two areas identified in this review that show promise for having therapeutic benefits for patients with IBD.
authors.affiliation: a Department of Medicine , Division of Gastroenterology, University of British Columbia , Vancouver , British Columbia , Canada.
authors.forename: Ashley
authors.initials: A
authors.lastname: Charlebois
authors.affiliation: b Division of Gastroenterology, Department of Medicine, St. Paul's Hospital , University of British Columbia , Vancouver , Canada.
authors.forename: Greg
authors.initials: G
authors.lastname: Rosenfeld
authors.affiliation: b Division of Gastroenterology, Department of Medicine, St. Paul's Hospital , University of British Columbia , Vancouver , Canada.
authors.forename: Brian
authors.initials: B
authors.lastname: Bressler
mesh_terms: D002986:Clinical Trials as Topic; D003093:Colitis, Ulcerative / Q000178:diet therapy; D003424:Crohn Disease / Q000178:diet therapy; D004032:Diet; D004043:Dietary Fiber / Q000008:administration & dosage; D063427:Food Quality; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000178:diet therapy*; D016239:MEDLINE
keywords: Crohn's disease; Inflammatory bowel disease; diet; exclusion diets; low FODMAP diet; nutrition; ulcerative colitis