title: Potentiation of 17β-estradiol on neuroexcitability by HCN-mediated neuromodulation of fast-afterhyperpolarization and late-afterdepolarization in low-threshold and sex-specific myelinated Ah-type baroreceptor neurons via GPR30 in female rats.
authors.affiliation: Department of Pharmacology, Harbin Medical University, Harbin, China.
authors.forename: Jian-Li
authors.initials: JL
authors.lastname: He
authors.affiliation: Department of Pharmacology, Harbin Medical University, Harbin, China.
authors.forename: Jun-Nan
authors.initials: JN
authors.lastname: Li
authors.affiliation: Department of Gynecology and Obstetrics, 211 Hospital of People's Liberation Army, Harbin, China.
authors.forename: Chun-Mei
authors.initials: CM
authors.lastname: Zuo
authors.affiliation: Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin Medical University, Harbin China.
authors.forename: Lu-Qi
authors.initials: LQ
authors.lastname: Wang
authors.affiliation: Department of Pharmacology, Harbin Medical University, Harbin, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wen
authors.affiliation: Department of Pharmacology, Harbin Medical University, Harbin, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Zuo
authors.affiliation: Department of Pharmacology, Harbin Medical University, Harbin, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Guan
authors.affiliation: Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin Medical University, Harbin China.
authors.forename: Di
authors.initials: D
authors.lastname: Wu
authors.affiliation: Department of Pharmacology, Harbin Medical University, Harbin, China.
authors.forename: Dong-Xue
authors.initials: DX
authors.lastname: Song
authors.affiliation: Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin Medical University, Harbin China.
authors.forename: Xue
authors.initials: X
authors.lastname: Yu
authors.affiliation: Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin Medical University, Harbin China.
authors.forename: Mei-Yu
authors.initials: MY
authors.lastname: Qu
authors.affiliation: Department of Pharmacology, Harbin Medical University, Harbin, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Pharmacology, Harbin Medical University, Harbin, China; Key Laboratory of Cardiovascular Research, Ministry of Education, Harbin Medical University, Harbin China.
authors.forename: Guo-Fen
authors.initials: GF
authors.lastname: Qiao
authors.affiliation: Department of Pharmacology, Harbin Medical University, Harbin, China. Electronic address: BYL3176033110@163.com.
authors.forename: Bai-Yan
authors.initials: BY
authors.lastname: Li
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D017704:Baroreflex / Q000187:drug effects / Q000502:physiology*; D004195:Disease Models, Animal; D004958:Estradiol / Q000494:pharmacology*; D004967:Estrogens / Q000494:pharmacology; D005260:Female; D009413:Nerve Fibers, Myelinated / Q000187:drug effects*; D009475:Neurons, Afferent / Q000187:drug effects* / Q000378:metabolism; D010052:Ovariectomy; D011311:Pressoreceptors / Q000187:drug effects* / Q000378:metabolism / Q000503:physiopathology; D051381:Rats; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism*
chemical_list: D004967:Estrogens; C520305:Gper1 protein, rat; D043562:Receptors, G-Protein-Coupled; D004958:Estradiol
keywords: 17β-estradiol; Baroreceptor neuron; Fast afterhyperpolarization; Hyperpolarization-activated current; Late afterdepolarization; Potentiation