title: [Post-stroke spasticity of the lower limb: a comprehensive rehabilitation of patients with the use of botulinum toxin (onabotulinumtoxin A)].
abstract: OBJECTIVE
  To examine the efficacy of onabotulinumtoxin A (Botox) in the complex rehabilitation of patients with post-stroke spasticity of the leg in the early rehabilitation period of stroke.
  
  
  METHODS
  The study group comprised 31 patients in the early recovery period after stroke with the presence of equino-varus deformity of the foot with spasticity grade 3 or more (MAS). All patients received injections of onabotulinumtoxin A (Botox) in a total dose 400 ED as part of a comprehensive rehabilitation program. Dynamics of neurological status, spasticity, pain, function of walking and everyday activity was evaluated. RESULTS AND СONCLUSION: The high efficacy of botulinum neurotoxin type A was demonstrated. The drug reduced the severity of spasticity and discomfort in the leg and foot; promoted independent movement and increased walking speed of the patient.
authors.forename: E V
authors.initials: EV
authors.lastname: Kostenko
authors.forename: L V
authors.initials: LV
authors.lastname: Petrova
mesh_terms: D065087:Acetylcholine Release Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D019274:Botulinum Toxins, Type A / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000209:etiology / Q000534:rehabilitation; D020521:Stroke / Q000150:complications; D000071939:Stroke Rehabilitation
chemical_list: D065087:Acetylcholine Release Inhibitors; D019274:Botulinum Toxins, Type A