title: Recurrent stuck mitral valve: eosinophilia an unusual pathology.
abstract: Eosinophilia is a very unusual and rare cause of thrombosis of prosthetic mitral valve. We report a 10-year-old male child of recurrent stuck prosthetic mitral valve. The child underwent mitral valve replacement for severe mitral regurgitation secondary to Rheumatic heart disease. He had recurrent prosthetic mitral valve thrombosis, despite desired INR levels. There was associated eosinophilia. The child was treated on the lines of tropical eosinophilia with oral prednisolone and diethylcarbamazine, the eosinophil count dropped significantly with no subsequent episode of stuck mitral valve. We discuss the management of recurrent stuck mitral valve and also eosinophilia as a causative factor for the same.
authors.affiliation: Department of Pediatric Cardiology, Fortis Escorts Heart Institute and Research Center (EHIRC), Okhla road, New Delhi, 110025, India, n_awasthy@yahoo.com.
authors.forename: Neeraj
authors.initials: N
authors.lastname: Awasthy
authors.forename: Yasser
authors.initials: Y
authors.lastname: Bhat
authors.forename: S
authors.initials: S
authors.lastname: Radhakrishnan
authors.forename: Rajesh
authors.initials: R
authors.lastname: Sharma
mesh_terms: D002648:Child; D004049:Diethylcarbamazine / Q000008:administration & dosage / Q000627:therapeutic use; D004802:Eosinophilia / Q000150:complications* / Q000188:drug therapy / Q000209:etiology; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D016859:Lipoxygenase Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008943:Mitral Valve / Q000473:pathology / Q000601:surgery; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D012214:Rheumatic Heart Disease / Q000150:complications*; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D016859:Lipoxygenase Inhibitors; D011239:Prednisolone; D004049:Diethylcarbamazine