title: Efficacy of jollab in the treatment of depression in dyspeptic patients: a randomized double-blind controlled trial.
abstract: The current study aimed to evaluate the efficacy of jollab, a well-known beverage from traditional Persian medicine in the treatment of depression among patients suffering from functional dyspepsia. In a randomized, double-blind, placebo-controlled trial, a pair of 80 patients were enrolled in 2 parallel groups as Jollab and placebo. The Beck Depression Inventory-II questionnaire was used for the assessment. At all, 133 patients enrolling in the treatment and placebo groups ended the protocol. According to the outcomes, changes in scores between the 2 groups were statistically significant at the end of trial (P ≤ .001). Taken as a whole, treatment group was significantly more effective than the placebo. Focusing on nutritional and pharmaceutical properties, jollab may be introduced not only as a medication for depression and allied ailment but also a pleasant daily drink.
authors.affiliation: The School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Pasalar
authors.affiliation: The School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Rasool
authors.initials: R
authors.lastname: Choopani
authors.affiliation: Traditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Mosaddegh
authors.affiliation: Department of Pharmacognosy, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Kamalinejad
authors.affiliation: Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Abdolali
authors.initials: A
authors.lastname: Mohagheghzadeh
authors.affiliation: Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Fattahi
authors.affiliation: Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran zarm@sums.ac.ir.
authors.forename: Mohammad M
authors.initials: MM
authors.lastname: Zarshenas
authors.affiliation: Department of Biostatistics, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Peyman
authors.initials: P
authors.lastname: Jafari
authors.affiliation: Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Kamran Bagheri
authors.initials: KB
authors.lastname: Lankarani
mesh_terms: D000328:Adult; D001628:Beverages; D003865:Major Depressive Disorder / Q000150:complications* / Q000188:drug therapy* / Q000453:epidemiology; D004415:Dyspepsia / Q000150:complications*; D005260:Female; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D008519:Medicine, Traditional / Q000379:methods*; D008875:Middle Aged; D011795:Surveys and Questionnaires
keywords: functional dyspepsia; jollab; major depressive disorder; traditional Persian medicine