title: Practical, legal, and ethical issues in expanded access to investigational drugs.
authors.forename: Jonathan J
authors.initials: JJ
authors.lastname: Darrow
authors.forename: Ameet
authors.initials: A
authors.lastname: Sarpatwari
authors.forename: Jerry
authors.initials: J
authors.lastname: Avorn
authors.forename: Aaron S
authors.initials: AS
authors.lastname: Kesselheim
mesh_terms: D026688:Bioethical Issues; D017277:Drug Approval / Q000266:history / Q000331:legislation & jurisprudence*; D004345:Drug Industry; D015507:Drugs, Investigational / Q000266:history / Q000627:therapeutic use*; D033161:Government Regulation / Q000266:history; D006291:Health Policy / Q000331:legislation & jurisprudence*; D006297:Health Services Accessibility / Q000941:ethics / Q000331:legislation & jurisprudence; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D015507:Drugs, Investigational