title: A wireless implantable switched-capacitor based optogenetic stimulating system.
abstract: This paper presents a power-efficient implantable optogenetic interface using a wireless switched-capacitor based stimulating (SCS) system. The SCS efficiently charges storage capacitors directly from an inductive link and periodically discharges them into an array of micro-LEDs, providing high instantaneous power without affecting wireless link and system supply voltage. A custom-designed computer interface in LabVIEW environment wirelessly controls stimulation parameters through the inductive link, and an optrode array enables simultaneous neural recording along with optical stimulation. The 4-channel SCS system prototype has been implemented in a 0.35-μm CMOS process and combined with the optrode array. In vivo experiments involving light-induced local field potentials verified the efficacy of the SCS system. An implantable version of the SCS system with flexible hermetic sealing is under development for chronic experiments.
authors.forename: Hyung-Min
authors.initials: HM
authors.lastname: Lee
authors.forename: Ki-Yong
authors.initials: KY
authors.lastname: Kwon
authors.forename: Wen
authors.initials: W
authors.lastname: Li
authors.forename: Maysam
authors.initials: M
authors.lastname: Ghovanloo
mesh_terms: D000818:Animals; D025802:Electric Capacitance; D004867:Equipment Design; D020007:Implants, Experimental; D008962:Models, Theoretical; D062308:Optogenetics / Q000295:instrumentation* / Q000379:methods*; D017207:Rats, Sprague-Dawley; D014584:User-Computer Interface; D059015:Wireless Technology