title: Varying clinical and imaging outcomes in patients with spontaneous thrombosis of vein of Galen malformation--a report of two cases.
abstract: BACKGROUND
  Vein of Galen malformations are rare congenital intracranial vascular malformations. The pathophysiological consequences usually manifest as high-output cardiac failure and neurological symptoms secondary to cerebral venous congestion and abnormal CSF flow. Management of these patients is complex. Indications and time to intervene are decided depending upon the age of child, clinical presentation, and multisystemic neonatal scores. Many of these children presenting early and who are not in cardiac failure are expectantly followed up. Spontaneous thrombosis of the vein of Galen malformation is a rare occurrence in these as such rare vascular malformations.
  
  
  METHODS
  This review reports two cases of spontaneous thrombosis of the vein of Galen malformations with varying clinical as well as imaging outcomes. Possible pathophysiologic mechanisms are discussed with review of literature.
  
  
  RESULTS
  This report highlights the importance of vigilant clinical and imaging follow-up even after spontaneous thrombosis in the vein of Galen malformations.
authors.affiliation: Department of Imaging Sciences & Interventional Radiology, Sree Chitra Tirunal Institute for Medical Science and Technology, Trivandrum, 695011, India, nkj7245y@rediffmail.com.
authors.forename: Narendra Kumar
authors.initials: NK
authors.lastname: Jain
authors.forename: Sweta
authors.initials: S
authors.lastname: Swaika
authors.forename: Bejoy
authors.initials: B
authors.lastname: Thomas
authors.forename: C
authors.initials: C
authors.lastname: Kesavadas
authors.forename: T R
authors.initials: TR
authors.lastname: Kapilamoorthy
mesh_terms: D002533:Cerebral Angiography; D006801:Humans; D007223:Infant; D020767:Intracranial Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D008297:Male; D054080:Vein of Galen Malformations / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*