title: Rapid residue analysis of oxathiapiprolin and its metabolites in typical Chinese soil, water, and sediments by a modified quick, easy, cheap, effective, rugged, and safe method with ultra high performance liquid chromatography and tandem mass spectrometry.
abstract: A sensitive and effective method for the simultaneous determination of residues from a new fungicide, oxathiapiprolin, and its metabolites (IN-E8S72 and IN-WR791) in soil, water, and sediment, was developed using ultra high performance liquid chromatography with tandem mass spectrometry. Three compounds were extracted from water, soil, and sediment by using acetonitrile and different proportions of formic acid aqueous solution (1% v/v for water; 2% v/v for soil; and sediment), and were cleaned with octadecylsilane. The target compounds were determined within 5 min using an electrospray ionization source in the positive mode for oxathiapiprolin and in the negative mode for the two metabolites. The limits of quantification for all the three compounds were 0.1 μg/kg in water and 1 μg/kg in soil and sediment. Recovery studies were performed using three spiked levels (0.1, 1, and 10 μg/kg for water; 1, 10, and 50 μg/kg for soil and sediment). The overall average recoveries ranged from 64.8 to 112.7% with all intra- and interday relative standard deviation values below 19.4 and 19.1%, respectively. The method validation confirmed that the proposed method was convenient and reliable for determining residual oxathiapiprolin and its metabolites in soil, water, and sediments.
authors.affiliation: State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Ju
authors.forename: Fengshou
authors.initials: F
authors.lastname: Dong
authors.forename: Xingang
authors.initials: X
authors.lastname: Liu
authors.forename: Xiaohu
authors.initials: X
authors.lastname: Wu
authors.forename: Huanhuan
authors.initials: H
authors.lastname: Zhao
authors.forename: Yongquan
authors.initials: Y
authors.lastname: Zheng
authors.forename: Jun
authors.initials: J
authors.lastname: Xu
mesh_terms: D005591:Chemical Fractionation; D002681:China; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004350:Drug Residues / Q000737:chemistry / Q000302:isolation & purification; D005659:Fungicides, Industrial / Q000737:chemistry* / Q000302:isolation & purification; D019015:Geologic Sediments / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry* / Q000302:isolation & purification; D011720:Pyrazoles / Q000737:chemistry* / Q000302:isolation & purification; D012989:Soil Pollutants / Q000737:chemistry* / Q000302:isolation & purification; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D005659:Fungicides, Industrial; D006845:Hydrocarbons, Fluorinated; D011720:Pyrazoles; D012989:Soil Pollutants; D014874:Water Pollutants, Chemical; C000592431:oxathiapiprolin
keywords: Metabolites; Oxathiapiprolin; Sediment; Soil; Water