title: [Organic erectile dysfunction and metabolic syndrome in young and middle-aged men: analysis of 154 cases].
abstract: OBJECTIVE
  To investigate the association of erectile dysfunction (ED) with metabolic syndrome ( MS) and the total testosterone ( tT) level in young and middle-aged men.
  
  
  METHODS
  This study included 154 organic ED outpatients aged 20 -59 years and 103 age-matched men with normal sexual life. We obtained their waist circumference ( WC) , blood pressure ( BP) , fasting blood glucose ( FBG) , triglyceride ( TG) , high density lipoprotein ( HDL) , tT, IIEF -5 score, erectile function indexes and other relevant variables, and compared them between the ED and non-ED groups as well as between the ED patients with MS and those without MS.
  
  
  RESULTS
  The prevalence of MS was significantly higher in the ED patients than in the non-ED males ( 40. 9 vs 17.4%, P < 0. 01). Statistically significant differences were found between the ED and non-ED groups in WC ( [90. 80 ±4. 90] vs [87. 70 ±4. 60] em, P <0.01), SBP ([134.40±14.40] vs [129.90±12.40] mmHg, P<O.OS), DBP ([86.20±7.80] vs [83.60±8.60] mmHg, P <0.05), FBG ( [5.48 ±1.02] vs [5. 11 ±0. 91] mmol, P <0. 01), HDL ( [ 1.12 ±0. 27] vs [ 1. 26 ±0. 29] mmol, P < 0. 01) , and tT ( [ 15. 98 ± 6. 55] vs [ 17. 95 ± 7. 39] mmol, P < 0. 05) , as well as between the ED patients with MS and those without MS in such erectile function indexes as tT ( [ 14.49 ±6. 23] vs [ 17.01 ±6. 60] mmol, P <0. 05), erectile penile circumference ( [9. 67 ± 1.09] vs [10.16 ± 1.01] cm, P <0. 01), erectile penile length ( [ 10.40 ± 1. 20] vs [ 10.79 ± 1. 07] cm, P <0. 05), glans temperature ( [ 31. 33 ± 0. 65] vs [ 31. 80 ± 0. 82] °C , P < 0. 01) , and mean axial hardness of the penis ( [ 332. 60 ± 137. 90] vs [ 419. 20 ± 145. 80] g, P < 0. 01 ) . WC was significantly correlated with the incidence of ED ( P < 0. 01 ) .
  
  
  CONCLUSIONS
  The prevalence of MS is significantly higher in young and middle-aged ED patients than in normal males, and MS is associated with a lower testosterone level and poorer erectile performance. Central obesity is closely correlated with ED in young and middle-aged men.
authors.affiliation: Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiatong University, China.  769233885@qq.com
authors.forename: Jie
authors.initials: J
authors.lastname: Ding
authors.forename: Hesuti
authors.initials: H
authors.lastname: Ma
authors.forename: Di
authors.initials: D
authors.lastname: Xi
authors.forename: Hong-yi
authors.initials: HY
authors.lastname: Qiu
authors.forename: Min
authors.initials: M
authors.lastname: Ye
authors.forename: Jun
authors.initials: J
authors.lastname: Qi
authors.forename: Qiang
authors.initials: Q
authors.lastname: Bai
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D007172:Erectile Dysfunction / Q000097:blood / Q000209:etiology*; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D008875:Middle Aged; D010410:Penile Erection / Q000502:physiology; D015995:Prevalence; D013739:Testosterone / Q000097:blood; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference; D055815:Young Adult
chemical_list: D014280:Triglycerides; D013739:Testosterone; D002784:Cholesterol