title: Modular and highly stereoselective approach to all-carbon tetrasubstituted alkenes.
abstract: A modular and completely stereoselective approach for the construction of all-carbon tetrasubstituted alkenes is described. It is based on the three-fold, sequential metal-catalyzed, cross-coupling functionalization of simple enolphosphate dibromide templates with carbon nucleophiles, affording tetrasubstituted alkenes as single isomers.
authors.affiliation: Department of Organic Chemistry and ‡Laboratory of NMR Spectroscopy, University of Chemistry and Technology, Prague , Technická 5, 166 28 Prague 6, Czech Republic.
authors.forename: Vladislav
authors.initials: V
authors.lastname: Kotek
authors.forename: Hana
authors.initials: H
authors.lastname: Dvořáková
authors.forename: Tomáš
authors.initials: T
authors.lastname: Tobrman
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D006842:Hydrocarbons, Brominated; D010165:Palladium; C008756:palladium chloride