title: An organocatalytic biomimetic approach to α-aminophosphonates.
abstract: A novel biomimetic approach to optically active α-aminophosphonates utilizing readily available acylphosphonates and 2-chlorobenzylamine as starting materials has been described. The enantioselective protonation constitutes the main enantiodifferentiating step in the developed strategy. This nature-inspired approach proceeds efficiently and in a highly stereoselective manner.
authors.affiliation: Institute of Organic Chemistry, Chemistry Department, Lodz University of Technology, Żeromskiego 116, 90-924 Łódź, Poland. lukasz.albrecht@p.lodz.pl.
authors.forename: Dorota
authors.initials: D
authors.lastname: Kowalczyk
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Albrecht
mesh_terms: D032701:Biomimetics; D002384:Catalysis; D007097:Imines / Q000737:chemistry; D007536:Isomerism; D063065:Organophosphonates / Q000737:chemistry*
chemical_list: D007097:Imines; D063065:Organophosphonates