title: Longitudinal in-vivo volumetry study for porcine liver regeneration from CT data.
abstract: The use of hepatic-like cloned cord lining epithelial cells (CLEC) to enhance liver regeneration has been proposed, but has not been properly investigated in a large animal study. The paper presents a system developed for the longitudinal in-vivo volumetry study on porcine liver regeneration from computed tomography (CT) data. In this system, a rough 3D liver volume is firstly automatically segmented by a 3D mesh deformation-based method. Then a refinement step to eliminate the segmentation error is carried out by a 3D post-editing tool, followed by mesh-volume conversion and volume calculation. This system was applied in a pilot study, which was composed of 4/4 pigs in the Experimental/Control Groups, to measure liver volumes over pre- to post-operative time course. Experimental results suggest that (1) the developed system can perform CT-based porcine liver volumetry efficiently, and (2) the infusion of CLEC to liver remnant may potentially enhance the liver regeneration.
authors.forename: Jiayin
authors.initials: J
authors.lastname: Zhou
authors.forename: Weimin
authors.initials: W
authors.lastname: Huang
authors.forename: Stephen K Y
authors.initials: SK
authors.lastname: Chang
authors.forename: Wei
authors.initials: W
authors.lastname: Xiong
authors.forename: Thiha
authors.initials: T
authors.lastname: Oo
authors.forename: Wenyu
authors.initials: W
authors.lastname: Chen
mesh_terms: D000818:Animals; D001331:Automation; D021621:Imaging, Three-Dimensional; D008099:Liver / Q000000981:diagnostic imaging*; D008115:Liver Regeneration; D008137:Longitudinal Studies; D013552:Swine; D014057:Tomography, X-Ray Computed