title: Training and cardiovascular responses from cigarette smoke exposure.
abstract: The aim of this study was to evaluate the early effect of the endurance training (ET) on systolic blood pressure (SBP), heart rate (HR) and rate pressure-product (RPP) after acute cigarette smoke exposure. Twenty male Wistar rats were randomly allocated into two groups: trained (TEx; n = 10) and control (CEx; n = 10), exposed to smoke. TEx rats undertook ET during 2 weeks (swimming, 5 days/week; 1 h/session) and CEx group was kept in sedentary lifestyle. After ET protocol both groups were exposed to cigarette smoke only once (total 1 h; 2 × 30 min with interval of 10 min between exposures; rate of 10 cigarettes/30 min). SBP, HR and RPP were measured after 2 weeks and just after (5 min) acute cigarette smoke (tail plethysmograph). All parameters did not differ (P > 0.05) between TEx (RPP = 45018 ± 1970 mmHg/bpm) and CEx (43695 ± 2579 mmHg/bpm) after ET protocol. However, all cardiovascular parameters increased (P < 0.05) only for CEx just after the cigarette smoke exposure. We concluded that ET can attenuate the aggression from acute smoking to cardiovascular system, with a few days of training and even with no chronic effect on these parameters at basal condition.
authors.affiliation: Federal University of Espírito Santo - Vitória - ES - Brazil.
authors.forename: Felipe Gonçalves Dos Santos
authors.initials: FG
authors.lastname: de Sá
authors.forename: Gustavo Ribeiro
authors.initials: GR
authors.lastname: da Mota
authors.forename: Paula Grippa
authors.initials: PG
authors.lastname: Sant'Ana
authors.forename: Márcia Regina Holanda
authors.initials: MR
authors.lastname: da Cunha
authors.forename: Moacir
authors.initials: M
authors.lastname: Marocolo
authors.forename: Edson
authors.initials: E
authors.lastname: Castardeli
mesh_terms: D000818:Animals; D001794:Blood Pressure; D006339:Heart Rate; D008297:Male; D010805:Physical Conditioning, Animal; D010807:Physical Endurance; D051381:Rats; D017208:Rats, Wistar; D012906:Smoke / Q000009:adverse effects*; D014026:Nicotiana / Q000009:adverse effects*
chemical_list: D012906:Smoke