title: Liquid chromatography-electrospray ionization tandem mass spectrometry and dynamic multiple reaction monitoring method for determining multiple pesticide residues in tomato.
abstract: A quick and sensitive liquid chromatography-electrospray ionization tandem mass spectrometry method, using dynamic multiple reaction monitoring and a 1.8-μm particle size analytical column, was developed to determine 57 pesticides in tomato in a 13-min run. QuEChERS (quick, easy, cheap, effective, rugged, and safe) method for samples preparations and validations was carried out in compliance with EU SANCO guidelines. The method was applied to 58 tomato samples. More than 84% of the compounds investigated showed limits of detection equal to or lower than 5 mg kg(-1). A mild (<20%), medium (20-50%), and strong (>50%) matrix effect was observed for 72%, 25%, and 3% of the pesticides studied, respectively. Eighty-one percent of the pesticides showed recoveries ranging between 70% and 120%. Twelve pesticides were detected in 35 samples, all below the maximum residue levels permitted in the Brazilian legislation; 15 samples exceeded the maximum residue levels established by the EU legislation for methamidophos; and 10 exceeded limits for acephate and four for bromuconazole.
authors.affiliation: Centro de Energia Nuclear na Agricultura, Laboratório de Ecotoxicologia, Avenida Centenário 303, 13416-903 Piracicaba, SP, Brazil. Electronic address: grazielacrm@yahoo.com.br.
authors.forename: G C R M
authors.initials: GC
authors.lastname: Andrade
authors.affiliation: Centro de Energia Nuclear na Agricultura, Laboratório de Ecotoxicologia, Avenida Centenário 303, 13416-903 Piracicaba, SP, Brazil; Instituto Biológico, Av. Conselheiro Rodrigues Alves, 1252, Vila Mariana, 04014-002 São Paulo, SP, Brazil.
authors.forename: S H
authors.initials: SH
authors.lastname: Monteiro
authors.affiliation: Centro de Energia Nuclear na Agricultura, Laboratório de Ecotoxicologia, Avenida Centenário 303, 13416-903 Piracicaba, SP, Brazil.
authors.forename: J G
authors.initials: JG
authors.lastname: Francisco
authors.affiliation: Centro de Energia Nuclear na Agricultura, Laboratório de Ecotoxicologia, Avenida Centenário 303, 13416-903 Piracicaba, SP, Brazil.
authors.forename: L A
authors.initials: LA
authors.lastname: Figueiredo
authors.affiliation: Centro de Energia Nuclear na Agricultura, Laboratório de Ecotoxicologia, Avenida Centenário 303, 13416-903 Piracicaba, SP, Brazil.
authors.forename: R G
authors.initials: RG
authors.lastname: Botelho
authors.affiliation: Centro de Energia Nuclear na Agricultura, Laboratório de Ecotoxicologia, Avenida Centenário 303, 13416-903 Piracicaba, SP, Brazil.
authors.forename: V L
authors.initials: VL
authors.lastname: Tornisielo
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D005638:Fruit / Q000737:chemistry*; D018551:Solanum lycopersicum / Q000737:chemistry*; D010573:Pesticide Residues / Q000032:analysis*; D010575:Pesticides / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
chemical_list: D010573:Pesticide Residues; D010575:Pesticides
keywords: Acephate (PubChem CID: 1982); Acetamiprid (PubChem CID: 213021); Benalaxyl (PubChem CID: 51369); Bromuconazole (PubChem CID: 3444); Buprofezin (PubChem CID: 50367); Cymoxanil (PubChem CID: 5364079); LC–ESI-MS/MS; Methamidophos (PubChem CID: 4096); Metolachlor (PubChem CID: 4169); Monuron (PubChem CID: 8800); Pesticides; Pyrimiphos methyl (PubChem CID: 34526); QuEChERS; Tomato