title: Phantom materials mimicking the optical properties in the near infrared range for non-invasive fetal pulse oximetry.
abstract: An optical phantom of the maternal abdomen during pregnancy is an appropriate test environment to evaluate a non-invasive system for fetal pulse oximetry. To recreate the optical properties of maternal tissue, fetal tissue and blood suitable substitutes are required. For this purpose, phantom materials are used, which consist of transparent silicone or water as host material. Cosmetic powder and India ink are investigated as absorbing materials, whereas titanium dioxide particles are examined as scattering medium. Transmittance and reflectance measurements of the samples were performed in the spectral range from 600 nm to 900 nm using integrating sphere technique. The scattering and absorption coefficients and the anisotropy factor were determined using Kubelka-Munk theory. The results were used to compute the required mixture ratios of the respective components to replicate the optical properties of maternal tissue, fetal tissue and blood, and corresponding samples were produced. Their optical properties were investigated in the same manner as mentioned above. The results conform to the values of various types of tissues and blood given in the scientific literature.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Ley
authors.forename: Miriam
authors.initials: M
authors.lastname: Stadthalter
authors.forename: Dietmar
authors.initials: D
authors.lastname: Link
authors.forename: Daniel
authors.initials: D
authors.lastname: Laqua
authors.forename: Peter
authors.initials: P
authors.lastname: Husar
mesh_terms: D016880:Anisotropy; D001769:Blood; D002244:Carbon / Q000737:chemistry; D003358:Cosmetics; D005260:Female; D005333:Fetus / Q000502:physiology*; D006801:Humans; D007259:Infrared Rays; D055620:Optical Phenomena; D010092:Oximetry / Q000379:methods*; D019047:Phantoms, Imaging; D011208:Powders; D011247:Pregnancy; D011674:Pulse; D014025:Titanium / Q000737:chemistry
chemical_list: D003358:Cosmetics; D011208:Powders; C028433:chinese ink; C009495:titanium dioxide; D002244:Carbon; D014025:Titanium