title: Cerebral oscillatory activity during simulated driving using MEG.
abstract: We aimed to examine cerebral oscillatory differences associated with psychological processes during simulated car driving. We recorded neuromagnetic signals in 14 healthy volunteers using magnetoencephalography (MEG) during simulated driving. MEG data were analyzed using synthetic aperture magnetometry to detect the spatial distribution of cerebral oscillations. Group effects between subjects were analyzed statistically using a non-parametric permutation test. Oscillatory differences were calculated by comparison between "passive viewing" and "active driving." "Passive viewing" was the baseline, and oscillatory differences during "active driving" showed an increase or decrease in comparison with a baseline. Power increase in the theta band was detected in the superior frontal gyrus (SFG) during active driving. Power decreases in the alpha, beta, and low gamma bands were detected in the right inferior parietal lobe (IPL), left postcentral gyrus (PoCG), middle temporal gyrus (MTG), and posterior cingulate gyrus (PCiG) during active driving. Power increase in the theta band in the SFG may play a role in attention. Power decrease in the right IPL may reflect selectively divided attention and visuospatial processing, whereas that in the left PoCG reflects sensorimotor activation related to driving manipulation. Power decreases in the MTG and PCiG may be associated with object recognition.
authors.affiliation: Department of Functional Diagnostic Science, Graduate School of Medicine, Osaka University Suita, Japan ; Department of Clinical Laboratory Science, Faculty of Medical Technology, Teikyo University Itabashi-ku, Japan.
authors.forename: Kotoe
authors.initials: K
authors.lastname: Sakihara
authors.affiliation: Department of Functional Diagnostic Science, Graduate School of Medicine, Osaka University Suita, Japan ; Department of Neurosurgery, Graduate School of Medicine, Osaka University Suita, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Hirata
authors.affiliation: Frontier Research Center, Toyota Central R&D Labs., Inc., Nagakute, Japan.
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Ebe
authors.affiliation: Human System Integration Group, Vehicle Engineering Development Division, Toyota Motor Corporation Toyota, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kimura
authors.affiliation: Department of Functional Diagnostic Science, Graduate School of Medicine, Osaka University Suita, Japan.
authors.forename: Seong
authors.initials: S
authors.lastname: Yi Ryu
authors.affiliation: Department of Functional Diagnostic Science, Graduate School of Medicine, Osaka University Suita, Japan.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Kono
authors.affiliation: Department of Functional Diagnostic Science, Graduate School of Medicine, Osaka University Suita, Japan.
authors.forename: Nozomi
authors.initials: N
authors.lastname: Muto
authors.affiliation: Department of Functional Diagnostic Science, Graduate School of Medicine, Osaka University Suita, Japan.
authors.forename: Masako
authors.initials: M
authors.lastname: Yoshioka
authors.affiliation: Department of Neurosurgery, Graduate School of Medicine, Osaka University Suita, Japan.
authors.forename: Toshiki
authors.initials: T
authors.lastname: Yoshimine
authors.affiliation: Department of Functional Diagnostic Science, Graduate School of Medicine, Osaka University Suita, Japan.
authors.forename: Shiro
authors.initials: S
authors.lastname: Yorifuji
keywords: car driving; magnetoencephalography; oscillation