title: The infant microbiome development: mom matters.
abstract: The infant microbiome plays an essential role in human health and its assembly is determined by maternal-offspring exchanges of microbiota. This process is affected by several practices, including Cesarean section (C-section), perinatal antibiotics, and formula feeding, that have been linked to increased risks of metabolic and immune diseases. Here we review recent knowledge about the impacts on infant microbiome assembly, discuss preventive and restorative strategies to ameliorate the effects of these impacts, and highlight where research is needed to advance this field and improve the health of future generations.
authors.affiliation: Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, NY, USA; Institute of Human Nutrition and Department of Medicine, College of Physicians and Surgeons, Columbia University Medical Center, New York, NY, USA.
authors.forename: Noel T
authors.initials: NT
authors.lastname: Mueller
authors.affiliation: Division of Translational Medicine, New York University School of Medicine, New York, NY, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Bakacs
authors.affiliation: School of Nursing, New York University, New York, NY, USA.
authors.forename: Joan
authors.initials: J
authors.lastname: Combellick
authors.affiliation: Division of Translational Medicine, New York University School of Medicine, New York, NY, USA.
authors.forename: Zoya
authors.initials: Z
authors.lastname: Grigoryan
authors.affiliation: Division of Translational Medicine, New York University School of Medicine, New York, NY, USA. Electronic address: Maria.Dominguez-Bello@nyumc.org.
authors.forename: Maria G
authors.initials: MG
authors.lastname: Dominguez-Bello
mesh_terms: D005260:Female; D041981:Gastrointestinal Tract / Q000382:microbiology; D006801:Humans; D007223:Infant; D007229:Infant Welfare; D008297:Male; D064307:Microbiota; D009035:Mothers; D011247:Pregnancy