title: Toxicity of a neonicotinoid insecticide, guadipyr, in earthworm (Eisenia fetida).
abstract: Neonicotinoid insecticides are new class of pesticides and it is very meaningful to evaluate the toxicity of guadipyr to earthworm (Eisenia fetida). In the present study, effects of guadipyr on reproduction, growth, catalase(CAT), superoxide dismutase (SOD), acetylcholinesterase (AChE) and DNA damage in earthworm were assessed using an artificial soil medium. Guadipyr showed low toxicity to earthworms and did not elicit an effect on earthworm reproduction or growth in artificial soils at concentrations <100mg/kg. However, after exposure to guadipyr, the activity of SOD and CAT in earthworm increased and then decreased to control level. AChE activity decreased at day 3 at 50 and 100mg/kg and then increased to control level. Our data indicate that guadipyr did not induce DNA damage in earthworms at concentration of <100mg/kg.
authors.affiliation: College of Sciences, China Agricultural University, Beijing, People's Republic of China.
authors.forename: Kai
authors.initials: K
authors.lastname: Wang
authors.affiliation: College of Sciences, China Agricultural University, Beijing, People's Republic of China.
authors.forename: Xiyan
authors.initials: X
authors.lastname: Mu
authors.affiliation: College of Sciences, China Agricultural University, Beijing, People's Republic of China.
authors.forename: Suzhen
authors.initials: S
authors.lastname: Qi
authors.affiliation: College of Sciences, China Agricultural University, Beijing, People's Republic of China.
authors.forename: Tingting
authors.initials: T
authors.lastname: Chai
authors.affiliation: College of Sciences, China Agricultural University, Beijing, People's Republic of China.
authors.forename: Sen
authors.initials: S
authors.lastname: Pang
authors.affiliation: College of Sciences, China Agricultural University, Beijing, People's Republic of China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.affiliation: College of Sciences, China Agricultural University, Beijing, People's Republic of China. Electronic address: Wangchengju@cau.edu.cn.
authors.forename: Chengju
authors.initials: C
authors.lastname: Wang
authors.affiliation: College of Sciences, China Agricultural University, Beijing, People's Republic of China. Electronic address: 97066h@cau.edu.cn.
authors.forename: Jiazhen
authors.initials: J
authors.lastname: Jiang
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D002374:Catalase / Q000378:metabolism; D020552:Comet Assay; D004249:DNA Damage; D004305:Dose-Response Relationship, Drug; D006146:Guanidines / Q000633:toxicity*; D007306:Insecticides / Q000633:toxicity*; D007928:Lethal Dose 50; D009835:Oligochaeta / Q000187:drug effects / Q000254:growth & development; D012098:Reproduction / Q000187:drug effects; D012989:Soil Pollutants / Q000633:toxicity*; D013482:Superoxide Dismutase / Q000378:metabolism; D023382:Toxicity Tests, Acute; D059550:Toxicity Tests, Subchronic
chemical_list: C587227:Guadipyr; D006146:Guanidines; D007306:Insecticides; D012989:Soil Pollutants; D002374:Catalase; D013482:Superoxide Dismutase; D000110:Acetylcholinesterase
keywords: Antioxidase; DNA damage; Earthworm; Guadipyr; Toxicity evaluation