title: Closure of chronic non healing ankle ulcer with low level laser therapy in a patient presenting with thalassemia intermedia: Case report.
abstract: In this single case study, the possible effect of low-level laser therapy (LLLT) was explored in the form of light emitting diodes on a chronic non-healing wound of 6 months duration in an 18-year-old male patient suffering from thalassemia intermedia. After irradiation, with LLLT dosage of 17.3 J/cm(2) for 8 min for 2 weeks duration followed by proliferative dosage of 8.65-4.33 J/cm(2) for 4 min from 3(rd) week to 6(th) week for 2 min along with antibiotics vancomycin (15 mg/kg) and a combination of amoxicillin and clavulanic acid (1 g). Proliferation of healthy granulation tissue was observed with decrease in score of pressure ulcer scale with complete re-epithelialization eventually LLLT irradiation could be a novel method of treatment for chronic non-healing wound in a thalassemia intermedia patient and an useful adjunct to standard care of treatment of pressure ulcers. It is postulated that LED irradiation augments wound healing with an early closure and no recurrence at the irradiated site even after follow up of 6 months.
authors.affiliation: Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Manipal, Karnataka, India.
authors.forename: Snehil
authors.initials: S
authors.lastname: Dixit
authors.affiliation: Department of Physiotherapy, School of Allied Health Sciences, Manipal, Karnataka, India.
authors.forename: Parul Raj
authors.initials: PR
authors.lastname: Agrawal
authors.affiliation: Department of Prosthodontics, Manipal College of Dental Sciences, Manipal, Karnataka, India.
authors.forename: Dinesh Kumari
authors.initials: DK
authors.lastname: Sharma
authors.affiliation: Department of Community Medicine, Manipal University, Manipal, Karnataka, India.
authors.forename: Ravindra Pratap
authors.initials: RP
authors.lastname: Singh
keywords: Light emitting diodes; re-epithelialization; thalassemia; wound healing