title: Efficacy of green tea extract in two exercise models.
abstract: Oral administration of green tea extract in a dose of 6 mg/kg twice a day (before and after exercise) over 2 weeks significantly increased swimming times on week 1 and 2 in comparison with control animals receiving water. The 7-day and final exhaustive running in rats was accompanied by a significant decrease in spleen weight and iron serum levels associated with developed reticulocytosis. Administration of green tea extract in a dose of 12 mg/kg once a day (before exercise) for 2 weeks did not affect the duration of the running, but prevented the decrease in serum iron and spleen weight, that, along with a significantly increased concentration of reduced glutathione in erythrocytes, can indicate a normalizing effect of green tea extract on hemopoiesis and stimulating effect on the antioxidant system of erythrocytes.
authors.affiliation: I. M. Sechenov Institute for Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia, artnov20081@rambler.ru.
authors.forename: A V
authors.initials: AV
authors.lastname: Novozhilov
authors.forename: T V
authors.initials: TV
authors.lastname: Tavrovskaya
authors.forename: N G
authors.initials: NG
authors.lastname: Voitenko
authors.forename: M N
authors.initials: MN
authors.lastname: Maslova
authors.forename: N V
authors.initials: NV
authors.lastname: Goncharov
authors.forename: V I
authors.initials: VI
authors.lastname: Morozov
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism; D005978:Glutathione / Q000097:blood; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010805:Physical Conditioning, Animal; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D045262:Reticulocytosis / Q000187:drug effects; D013154:Spleen / Q000187:drug effects* / Q000378:metabolism; D013662:Tea
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; D013662:Tea; D005978:Glutathione