title: [Effect of C60 fullerene on viscoelastic properties of human erythrocytes membrane].
abstract: The effect of C60 fullerene aqueous colloid solution (C60FAS) on viscoelastic properties of human erythrocytes membrane has been studied. It was established that the effect of C60FAS on erythrocytes depends on the medium osmolality and concentration of C60 fullerene in it. In particular, in isotonic solution (0,15 mol/l NaCl) adding C60 fullerene in concentrations from 0,7 to 28 μmol/l did not cause the hemolytic damage of cells. In hypotonic medium when introducing C60 fullerene (7 μmol/l concentration) at the beginning of erythrocyte hemolysis its stimulating effect was maximal and when adding C60FAS in 20 s after hemolysis start no this process stimulation is observed. This points to the changes in viscoelastic properties of erythrocyte membranes even during the first seconds of its interaction with C60 fullerene.
authors.forename: N M
authors.initials: NM
authors.lastname: Shpakova
authors.forename: O S
authors.initials: OS
authors.lastname: Nipot
authors.forename: I O
authors.initials: IO
authors.lastname: Ishchenko
authors.forename: S V
authors.initials: SV
authors.lastname: Pryluts'ka
authors.forename: K I
authors.initials: KI
authors.lastname: Bohuts'ka
authors.forename: V V
authors.initials: VV
authors.lastname: Cherepanov
authors.forename: B P
authors.initials: BP
authors.lastname: Sandomyrs'kyĭ
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Pryluts'kyĭ
mesh_terms: D003102:Colloids; D004548:Elasticity; D004910:Erythrocyte Membrane / Q000737:chemistry / Q000187:drug effects*; D037741:Fullerenes / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D009996:Osmotic Fragility / Q000187:drug effects; D012965:Sodium Chloride / Q000494:pharmacology; D013997:Time Factors; D014783:Viscosity
chemical_list: D003102:Colloids; D037741:Fullerenes; D012965:Sodium Chloride; C069837:fullerene C60