title: Diagnostic value of bronchoalveolar lavage in leukemic and bone marrow transplant patients: the impact of antimicrobial therapy.
abstract: There is significant morbidity and mortality from pneumonia in leukemic and bone marrow transplant patients. We sought to explore the diagnostic yield of bronchoalveolar lavage (BAL) in these patients with new pulmonary infiltrates. A retrospective chart review of approximately 200 Non- human immunodeficiency virus (HIV) leukemic and Hematopoietic stem cell transplantation (HSCT) patients who underwent bronchoscopy at a single academic cancer center was performed. Antimicrobial use for less than 24 hours at the time of BAL was associated with a higher yield in this population (56.8% versus 32.8%, p<0.001). This supports performing bronchoscopy with BAL within 24 hours of antimicrobial therapy in leukemic and HSCT patients.
authors.affiliation: Moffitt Cancer Center, 12902 Magnolia Drive. Tampa, Florida 33612-9497.
authors.forename: Abraham Tareq
authors.initials: AT
authors.lastname: Yacoub
authors.affiliation: University of South Florida. Morsani College of Medicine. Moffitt Cancer Center.
authors.forename: Dani
authors.initials: D
authors.lastname: Thomas
authors.affiliation: University of South Florida. Morsani College of Medicine. Moffitt Cancer Center.
authors.forename: Carol
authors.initials: C
authors.lastname: Yuan
authors.affiliation: University of South Florida.
authors.forename: Carolina
authors.initials: C
authors.lastname: Collazo
authors.affiliation: University of South Florida. Morsani College of Medicine. Moffitt Cancer Center.
authors.forename: John
authors.initials: J
authors.lastname: Greene
authors.affiliation: University of South Florida. Morsani College of Medicine. Moffitt Cancer Center.
authors.forename: Frank
authors.initials: F
authors.lastname: Walsh
authors.affiliation: University of South Florida. Morsani College of Medicine. Moffitt Cancer Center.
authors.forename: David
authors.initials: D
authors.lastname: Solomon
authors.affiliation: University of South Florida.
authors.forename: Skai
authors.initials: S
authors.lastname: Schwartz
authors.affiliation: James A. Haley Veterans Administration Hospital. University of South Florida. Morsani College of Medicine. Moffitt Cancer Center.
authors.forename: Arthur
authors.initials: A
authors.lastname: Andrews