title: Two new sulfated sesquiterpenoids from Petasites tricholobus.
abstract: Two new sulfated sesquiterpenoids, megastigman-7-ene-3, 5, 6, 9-tetrol-3-O-β-D-6'-sulfonated-glucopyranoside (1) and 3-O-β-D-6'-sulfonated-glucopyranosyl-6-(3-oxo-2-butenylidenyl)-1, 1, 5-trimethylcyclohexan-5-ol (2), along with one known sesquitepenoid compound icariside B1 (3) were isolated from the whole herb of Petasites tricholobus Franch. Their structures were identified by their chemical and spectroscopic characters. All obtained compounds were tested for their cytotoxicity against four cancer cell lines.
authors.affiliation: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Gao
authors.forename: Qi
authors.initials: Q
authors.lastname: Jia
authors.forename: Fu-Jiang
authors.initials: FJ
authors.lastname: Guo
authors.forename: Bo
authors.initials: B
authors.lastname: Li
authors.forename: Zhi-Jian
authors.initials: ZJ
authors.lastname: Xu
authors.forename: Yi-Ming
authors.initials: YM
authors.lastname: Li
authors.forename: Wei-Liang
authors.initials: WL
authors.lastname: Zhu
authors.forename: Kai-Xian
authors.initials: KX
authors.lastname: Chen
mesh_terms: D045744:Cell Line, Tumor; D006027:Glycosides / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D045792:Norisoprenoids / Q000302:isolation & purification / Q000494:pharmacology; D036901:Petasites / Q000737:chemistry*; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D006027:Glycosides; D045792:Norisoprenoids; D012717:Sesquiterpenes; C514141:icariside B1