title: [The results of carotid endarterectomy in patients with carotid arteries stenosis and chronic ischemic optical neuropathy].
abstract: It was estimated an efficiency of surgical and conservative treatment of patients with atherosclerotic carotid arteries stenosis and chronic ischemic optical neuropathy. The first group included 30 patients after carotid endarterectomy. The second group included 20 patients who underwent conservative treatment. The methods of investigation included determination of visual acuity, autorefractometry, direct and inverse ophthalmoscopy under mydriasis, computer static perimetry, assessment of functional status of optic nerve by using of threshold of electric sensitivity and lability, ultrasonic scanning of eyes arteries and carotid arteries. Follow-up terms were baseline, in one month and in one year after surgery or conservative treatment. Improvement of visual acuity on 0.1 and more in 1st/2nd groups was 9/2 (p=0.1629), in one year - 12/1 (p=0.0075). Improvement of field of vision: in 1 month in 1st/2nd groups it was 12/3 (p=0.0692), in 1 year - 17/1 (p=0.0002). The dynamics of neurological status: there was equal ratio of asymptomatic/symptomatic patients at baseline in subgroups. In the 1st group it was 19/11 vs. 16/4 in the 2nd group (p=0.3451). In 1 year after two kinds of treatment significant changes were revealed. There was 26/4 in the 1st group vs. 13/7 in the 2nd group (p=0.0902) with improvement only after carotid endarterectomy - 19/11 at baseline vs. 26/4 in 1 year (p=0.0716). Insignificant deterioration was diagnosed after conservative treatment - 16/4 vs. 13/7 (p=0.4801).
authors.forename: A V
authors.initials: AV
authors.lastname: Gavrilenko
authors.forename: A V
authors.initials: AV
authors.lastname: Kuklin
authors.forename: T N
authors.initials: TN
authors.lastname: Kiseleva
mesh_terms: D000368:Aged; D016893:Carotid Stenosis / Q000150:complications / Q000601:surgery; D057186:Comparative Effectiveness Research; D003941:Diagnostic Techniques, Ophthalmological; D016894:Endarterectomy, Carotid / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D005500:Follow-Up Studies; D006401:Hematologic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018917:Optic Neuropathy, Ischemic / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D063868:Patient Outcome Assessment; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology; D011184:Postoperative Period; D012426:Russia
chemical_list: D006401:Hematologic Agents