title: Primary desmoplastic small round cell tumor of upper cervical lymph nodes.
abstract: Desmoplastic small round cell tumors (DSRCT) are rare malignancies that typically arise in the abdominopelvic cavities. They are very uncommon in the head and neck region. We present a case of an 11-year-old Caucasian male with a primary cervical lymph node tumor in the neck. Fine-needle aspiration cytology, histopathologic examination, immunohistochemical staining, and molecular genetic testing led to the diagnosis of DSRCT. Due to the very limited number of cases reported and the lack of staging criteria, the preferred management approach remains uncertain.
authors.affiliation: Department of ENT, Zain and Al-Sabah Hospitals, Ministry of Health, State of Kuwait. Electronic address: f.alfaras@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: Faras
authors.affiliation: Department of Surgery, Al-Adan Hospital, Ministry of Health, State of Kuwait.
authors.forename: F
authors.initials: F
authors.lastname: Abo-Alhassan
authors.affiliation: Chairman of Oral and Maxillofacial Surgery, Al-Amiri Hospital, Ministry of Health, State of Kuwait.
authors.forename: A H
authors.initials: AH
authors.lastname: Hussain
authors.affiliation: Professor of Paediatric and Developmental Pathology, NIHR Senior Investigator, NIHR GOSH BRC Theme Lead Diagnostics and Imaging, Great Ormond Street Hospital and ICH (UCL), United Kingdom.
authors.forename: N J
authors.initials: NJ
authors.lastname: Sebire
authors.affiliation: Chairman of ENT College, Post-Graduate Training, Kuwait Institute of Medical Specialization (KIMS), ENT Department, Zain and Al-Sabah Hospitals, Ministry of Health, State of Kuwait.
authors.forename: A E
authors.initials: AE
authors.lastname: Al-Terki
mesh_terms: D044963:Biopsy, Fine-Needle; D002648:Child; D058405:Desmoplastic Small Round Cell Tumor / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D003952:Diagnostic Imaging; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D017404:In Situ Hybridization, Fluorescence; D008207:Lymphatic Metastasis; D008297:Male; D020133:Reverse Transcriptase Polymerase Chain Reaction