title: Does Gastrointestinal Dysmotility Predispose to Recurrent or Severe Forms of Clostridium difficile Infections?
abstract: Clostridium difficile infection (CDI) is the most common cause of hospital-acquired diarrhea. A limited number of studies have looked at the risk factors for recurrent CDI. Mitochondrial NeuroGastroIntestinal Encephalopathy (MNGIE) is a rare multisystemic disorder that causes gastrointestinal dysmotility. Herein we present a patient with MNGIE who suffered recurrent and severe C. difficile infection despite appropriate treatment. We aim to bring the gastroenterologist's attention to gastrointestinal dysmotility as a possible risk factor for the development of recurrent or severe forms of C. difficile infections.
authors.affiliation: University of Florida-Jacksonville, Jacksonville, FL 32209, USA.
authors.forename: Abdul Wahab
authors.initials: AW
authors.lastname: Hritani
authors.affiliation: University of Florida-Jacksonville, Jacksonville, FL 32209, USA.
authors.forename: Ahmad
authors.identifier: 0000-0003-3869-6122
authors.initials: A
authors.lastname: Alkaddour
authors.affiliation: University of Florida-Jacksonville, Jacksonville, FL 32209, USA.
authors.forename: Jeff
authors.initials: J
authors.lastname: House