title: [Evaluation on the hepatitis A vaccine in preventing hepatitis A infection in Tianjin, from 2000 to 2011].
abstract: OBJECTIVE
  Hepatitis A immunization strategies were carried out in 2001 in Tianjin. We wanted to evaluate the effectiveness of the strategies related to hepatitis A control programs and to provide the basis for further modification of the strategies.
  
  
  METHODS
  Descriptive epidemiology study was used to analyze the hepatitis A epidemic situation in 2000-2011 in Tianjin and to evaluate the disease reporting system. Hepatitis A vaccine coverage of target population and serum epidemiological study were carried out in 1999, 2005 and 2010 to check on the hepatitis A antibody levels so as to evaluate the immuno-barrier condition in the normal population. Cox-Stuart test was used to analyze the epidemic trend of hepatitis A and other intestinal infectious diseases in Tianjin.
  
  
  RESULTS
  The incidence rate of hepatitis A decreased from 2.89/100 000 in 2000 to 0.12/100 000 in 2011, and the percentage of hepatitis A in all types of viral hepatitis decreased from 8.02% in 2000 to 0.48% in 2011 in Tianjin. The positive rates of hepatitis A antibody also increased in the residents.
  
  
  CONCLUSIONS
  The hepatitis A vaccination program was successful in the programs on prevention and control of hepatitis A in Tianjin, China.
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: Zhilun
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China? Email: zhu515@sina.com.
authors.forename: Xiangjun
authors.initials: X
authors.lastname: Zhu
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: Yaxing
authors.initials: Y
authors.lastname: Ding
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Gao
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: Yongcheng
authors.initials: Y
authors.lastname: Li
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: Ailan
authors.initials: A
authors.lastname: Shan
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: Weidong
authors.initials: W
authors.lastname: Xia
mesh_terms: D002681:China / Q000453:epidemiology; D058872:Epidemics / Q000517:prevention & control*; D006506:Hepatitis A / Q000453:epidemiology / Q000517:prevention & control*; D035922:Hepatitis A Antibodies / Q000097:blood; D022362:Hepatitis A Vaccines / Q000008:administration & dosage*; D006801:Humans
chemical_list: D035922:Hepatitis A Antibodies; D022362:Hepatitis A Vaccines