title: Successful recovery from iatrogenic severe hypernatremia and severe metabolic acidosis resulting from accidental use of inappropriate bicarbonate concentrate for hemodialysis treatment.
abstract: Bicarbonate dialysis is the treatment modality of choice for correction of metabolic acidosis in chronic renal failure. However, improper selection of dialysate concentrate can result in life-threatening human errors. We report a case of iatrogenic severe hypernatremia (sodium 207 mEq/L) and severe metabolic acidosis (pH 6.65) that resulted due to accidental use of inappropriate bicarbonate concentrate for hemodialysis treatment. There was successful recovery in this patient with no neurological sequelae. To the best of our knowledge, this is the first case report in adults of severe hypernatremia along with severe metabolic acidosis due to error in the preparation of dialysis fluid.
authors.affiliation: Department of Anaesthesia and Critical Care, Institute of Kidney Diseases and Research Center and Institute of Transplantation Sciences, Civil Hospital Campus, Ahmedabad, Gujarat, India.
authors.forename: Guruprasad P
authors.initials: GP
authors.lastname: Bhosale
authors.forename: Veena R
authors.initials: VR
authors.lastname: Shah
mesh_terms: D000138:Acidosis / Q000139:chemically induced*; D001639:Bicarbonates / Q000008:administration & dosage / Q000009:adverse effects*; D002021:Buffers; D015314:Dialysis Solutions / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D006955:Hypernatremia / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*
chemical_list: D001639:Bicarbonates; D002021:Buffers; D015314:Dialysis Solutions