title: [PCR rationale for use of oral cephalosporins by oral surgery procedures].
abstract: The article presents the experience of PCR detection of DNA of pathogenic germs inducing odontogenic inflammation. Pus samples of 48 patients aged 18 to 68 years undergoing oral surgery because of apical periodontal lesions and pericoronitis. The results showed microorganisms associations revealed by PCR are sensitive to III generation cephalosporins. Effective oral regimen included 400 mg Ceftibuten once daily. The PCR results thus served as a rationale for use of oral cephalosporins by oral surgery procedures proved by clinical and immunological data in postoperative period.
authors.affiliation: Moskovskiĭ gosudarstvennyĭ mediko-stomatologicheskiĭ universitet im. A.I. Evdokimova, Moskva.
authors.forename: V N
authors.initials: VN
authors.lastname: Tsarev
authors.affiliation: Moskovskiĭ gosudarstvennyĭ mediko-stomatologicheskiĭ universitet im. A.I. Evdokimova, Moskva.
authors.forename: V I
authors.initials: VI
authors.lastname: Chuvilkin
authors.affiliation: Moskovskiĭ gosudarstvennyĭ mediko-stomatologicheskiĭ universitet im. A.I. Evdokimova, Moskva.
authors.forename: G D
authors.initials: GD
authors.lastname: Akhmedov
authors.affiliation: Moskovskiĭ gosudarstvennyĭ mediko-stomatologicheskiĭ universitet im. A.I. Evdokimova, Moskva.
authors.forename: E I
authors.initials: EI
authors.lastname: Chuvilkina
authors.affiliation: Dagestanskaia gosudarstvennaia meditsinskaia akademiia, Makhachkala.
authors.forename: F N
authors.initials: FN
authors.lastname: Gadzhiev
authors.affiliation: Moskovskiĭ gosudarstvennyĭ mediko-stomatologicheskiĭ universitet im. A.I. Evdokimova, Moskva.
authors.forename: I V
authors.initials: IV
authors.lastname: Nikitin
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification* / Q000472:pathogenicity; D000077722:Ceftibuten; D002511:Cephalosporins / Q000008:administration & dosage*; D004269:DNA, Bacterial / Q000032:analysis*; D005122:Exudates and Transudates / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019647:Oral Surgical Procedures; D010497:Pericoronitis / Q000382:microbiology / Q000601:surgery; D016133:Polymerase Chain Reaction / Q000379:methods*; D013492:Suppuration / Q000382:microbiology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D004269:DNA, Bacterial; D000077722:Ceftibuten