title: A case series of two glomus tumors of the gastrointestinal tract.
abstract: Two recent cases of glomus tumors (GTs) of the gastrointestinal tract presented with symptoms of GI bleeding. GTs, typically benign lesions of mesenchymal origin, are rarely seen in the GI tract, and most commonly involve the distal appendages. This case series discusses the tumor biology, presentation, imaging, endoscopic findings, pathology and management of GTs. While diagnosis of GTs is typically made on final surgical pathology, there are defining characteristics that can separate a GT from a gastrointestinal stromal tumor on endoscopic ultrasound (EUS) and CT imaging. The classic pathological findings are discussed, and surgical decision-making is reviewed. New developments in the form of EUS-guided biopsy and endoscopic submucosal dissection present new avenues for diagnosis and treatment of submucosal lesions of the GI tract, including GTs. While typically a benign tumor requiring no adjuvant therapy, this study discusses some very rare cases of metastatic GT in the literature.
authors.affiliation: Department of Surgery, Division of General Surgery, University of Ottawa, Ottawa, Canada sebennett@toh.on.ca.
authors.forename: Sean
authors.initials: S
authors.lastname: Bennett
authors.affiliation: Department of Medicine, Division of Gastroenterology, University of Ottawa, Ottawa, Canada.
authors.forename: Mindy
authors.initials: M
authors.lastname: Lam
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Canada.
authors.forename: Jason
authors.initials: J
authors.lastname: Wasserman
authors.affiliation: Department of Surgery, Division of General Surgery, University of Ottawa, Ottawa, Canada.
authors.forename: David
authors.initials: D
authors.lastname: Carver
authors.affiliation: Department of Medicine, Division of Gastroenterology, University of Ottawa, Ottawa, Canada.
authors.forename: Navaaz
authors.initials: N
authors.lastname: Saloojee
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Ottawa, Ottawa, Canada.
authors.forename: Terence
authors.initials: T
authors.lastname: Moyana
authors.affiliation: Department of Surgery, Division of General Surgery, University of Ottawa, Ottawa, Canada.
authors.forename: Rebecca A
authors.initials: RA
authors.lastname: Auer
authors.affiliation: Department of Surgery, Division of General Surgery, University of Ottawa, Ottawa, Canada.
authors.forename: John
authors.initials: J
authors.lastname: Lorimer