title: [Fecal microbiota transplantation: review].
abstract: Fecal microbiota transplantation (FMT) has gained an increasing medical interest, since the recognition of the role of disturbed microbiota in the development of various diseases. To date, FMT is an established treatment modality for multiple recurrent Clostridium difficile infection (RCDI), despite lack of standardization of the procedure. Persisting normalization of the disturbed colonic microbiota associated with RCDI seems to be responsible for the therapeutic effect of FMT. For other diseases, FMT should be considered strictly experimental, only offered to patients in an investigational clinical setting. Although the concept of FMT is appealing, current expectations should be damped until future evidence arises.
authors.affiliation: Laboratoire Clostridium difficile associé au CNR des anaérobies et du botulisme, unité du lutte contre les infections nosocomiales (UHLIN), hôpital Saint-Antoine, 184, rue du Faubourg-Saint-Antoine, 75012 Paris, France; Groupe de recherche clinique n(o) 2 EPIDIFF, université Pierre-et-Marie-Curie, 75012 Paris, France. Electronic address: frederic.barbut@sat.aphp.fr.
authors.forename: F
authors.initials: F
authors.lastname: Barbut
authors.affiliation: EA4043, faculté de pharmacie, université Paris Sud, 92290 Châtenay-Malabry, France; Service de microbiologie, hôpital Jean-Verdier, AP-HP, 93140 Bondy, France.
authors.forename: A
authors.initials: A
authors.lastname: Collignon
authors.affiliation: Écosystème intestinal, probiotiques, antibiotiques (EA4065), université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France.
authors.forename: M-J
authors.initials: MJ
authors.lastname: Butel
authors.affiliation: EA4043, faculté de pharmacie, université Paris Sud, 92290 Châtenay-Malabry, France; Académie nationale de pharmacie, 4, avenue de l'Observatoire, 75270 Paris cedex 06, France.
authors.forename: P
authors.initials: P
authors.lastname: Bourlioux
mesh_terms: D016360:Clostridioides difficile; D020345:Enterocolitis, Necrotizing / Q000628:therapy; D000069467:Fecal Microbiota Transplantation / Q000379:methods*; D005243:Feces / Q000382:microbiology; D006801:Humans; D064307:Microbiota
keywords: Clostridium difficile; Dysbiose intestinale; Fecal transplantation; Gut dysbiosis; Gut microbiota; Microbiote intestinal; Transplantation fécale