title: A novel single-layered MoS2 nanosheet based microfluidic biosensor for ultrasensitive detection of DNA.
abstract: Recently, MoS2 nanosheets were demonstrated to be able to spontaneously adsorb single-stranded DNA, acting as efficient dye quenchers. We herein report a novel microfluidic biosensor for fluorescent DNA detection based on single-layered MoS2 nanosheets. The proposed platform is simple, rapid and visible with high sensitivity and selectivity.
authors.affiliation: Pillar of Engineering Product Development, Singapore University of Technology and Design, 20 Dover Drive, Singapore 138682, Singapore. aiye@sutd.edu.sg.
authors.forename: Yinxi
authors.initials: Y
authors.lastname: Huang
authors.forename: Yumeng
authors.initials: Y
authors.lastname: Shi
authors.forename: Hui Ying
authors.initials: HY
authors.lastname: Yang
authors.forename: Ye
authors.initials: Y
authors.lastname: Ai
mesh_terms: D015374:Biosensing Techniques; D004247:DNA / Q000737:chemistry*; D004277:DNA, Single-Stranded; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry; D008422:Materials Testing; D044085:Microfluidics / Q000295:instrumentation / Q000379:methods*; D018625:Microscopy, Atomic Force; D053758:Nanoparticles / Q000737:chemistry; D049329:Nanostructures; D036103:Nanotechnology / Q000379:methods*; D055095:Optics and Photonics; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012996:Solutions; D013050:Spectrometry, Fluorescence; D013499:Surface Properties
chemical_list: D004277:DNA, Single-Stranded; D004129:Dimethylpolysiloxanes; D005456:Fluorescent Dyes; D012996:Solutions; C013830:baysilon; D004247:DNA