title: Panton-Valentine leukocidin osteomyelitis in children: a growing threat.
abstract: Panton-Valentine leukocidin-producing Staphylococcus aureus osteomyelitis is associated with multiple complications including multiple abscesses, deep vein thrombosis and fulminant sepsis. This article reviews the literature concerning this emerging threat which is currently under-recognized.
authors.affiliation: Specialty Registrar in the Department of Trauma and Orthopaedics.
authors.forename: Hassaan Q
authors.initials: HQ
authors.lastname: Sheikh
authors.forename: Adeel
authors.initials: A
authors.lastname: Aqil
authors.forename: Andrew
authors.initials: A
authors.lastname: Kirby
authors.forename: Fahad S
authors.initials: FS
authors.lastname: Hossain
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001427:Bacterial Toxins / Q000378:metabolism*; D002648:Child; D003646:Debridement; D005098:Exotoxins / Q000378:metabolism*; D006801:Humans; D007956:Leukocidins / Q000378:metabolism*; D010019:Osteomyelitis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D052880:Pyomyositis / Q000209:etiology; D018805:Sepsis / Q000209:etiology; D012720:Severity of Illness Index; D013203:Staphylococcal Infections / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D013211:Staphylococcus aureus / Q000378:metabolism*; D020246:Venous Thrombosis / Q000209:etiology
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin