title: NRG4: an endocrine link between brown adipose tissue and liver.
abstract: Brown adipose tissue (BAT) directly regulates energy homeostasis via uncoupling of mitochondrial ATP production and thermogenesis. Wang et al. (2014) now report that BAT controls liver lipogenesis via secretion of the growth factor NRG4.
authors.affiliation: Institute of Pharmacology and Toxicology, University of Bonn, 53127 Bonn, Germany. Electronic address: alexander.pfeifer@uni-bonn.de.
authors.forename: Alexander
authors.initials: A
authors.lastname: Pfeifer
mesh_terms: D002001:Adipose Tissue, Brown / Q000378:metabolism*; D000818:Animals; D006801:Humans; D050155:Lipogenesis; D008099:Liver / Q000378:metabolism*; D020880:Neuregulins / Q000235:genetics*; D009765:Obesity / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics*; D020893:Receptor, ErbB-3 / Q000378:metabolism*; D066247:Receptor, ErbB-4 / Q000378:metabolism*
chemical_list: D020880:Neuregulins; D012333:RNA, Messenger; D020893:Receptor, ErbB-3; D066247:Receptor, ErbB-4