title: The predominant myeloma clone at diagnosis, CDR3 defined, is constantly detectable across all stages of disease evolution.
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Puig
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Conde
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Jiménez
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: M E
authors.initials: ME
authors.lastname: Sarasquete
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Balanzategui
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Alcoceba
authors.affiliation: Department of Hematology, Hospital Miguel Servet, Zaragoza, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Quintero
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: M C
authors.initials: MC
authors.lastname: Chillón
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Sebastián
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Corral
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Marín
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: N C
authors.initials: NC
authors.lastname: Gutiérrez
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: M-V
authors.initials: MV
authors.lastname: Mateos
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: M
authors.initials: M
authors.lastname: González-Díaz
authors.affiliation: Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Pamplona, Spain.
authors.forename: J F
authors.initials: JF
authors.lastname: San-Miguel
authors.affiliation: 1] Department of Hematology, University Hospital of Salamanca, Salamanca, Spain [2] IBSAL, Salamanca, Spain [3] IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: R
authors.initials: R
authors.lastname: García-Sanz
mesh_terms: D060965:Clonal Evolution; D022801:Complementarity Determining Regions / Q000235:genetics*; D018450:Disease Progression; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000235:genetics*; D013997:Time Factors
chemical_list: D022801:Complementarity Determining Regions; D007143:Immunoglobulin Heavy Chains