title: Analysis of blood trace elements and biochemical indexes levels in severe craniocerebral trauma adults with Glasgow Coma Scale and injury severity score.
abstract: We aimed to investigate the correlation between the Glasgow Coma Scale (GCS), the injury severity score (ISS) and serum levels of trace elements (TE) in severe trauma patients to analyze alteration of the levels of trace elements and serum biochemical indexes in the period of admission from 126 adult cases of severe brain trauma with traffic accidents. Multi-trace elements for patients in the trauma-TE groups were used. The results indicated that all patients presented an acute trace elements deficiency syndrome (ATEDs) after severe trauma, and the correlation between ISS and serum levels of Fe, Zn, and Mg was significant. Compared to the normal control group, levels of the trace elements in serum were significantly decreased after trauma, suggesting that enhancement of immunity to infection and multiple organ failure (MOF) via the monitoring and supplement of trace elements will be a good strategy to severe traumatic patients in clinics.
authors.affiliation: National Key Disciplines, Department of Forensic and Pathology, Shantou University Medical College, 515041, Shantou, Guangdong Province, People's Republic of China, tsuigt@126.com.
authors.forename: Guangtao
authors.initials: G
authors.lastname: Xu
authors.forename: Bo
authors.initials: B
authors.lastname: Hu
authors.forename: Guiqian
authors.initials: G
authors.lastname: Chen
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Yu
authors.forename: Jianming
authors.initials: J
authors.lastname: Luo
authors.forename: Junyao
authors.initials: J
authors.lastname: Lv
authors.forename: Jiang
authors.initials: J
authors.lastname: Gu
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001806:Blood Urea Nitrogen; D003300:Copper / Q000097:blood*; D006259:Craniocerebral Trauma / Q000097:blood* / Q000175:diagnosis; D003404:Creatinine / Q000097:blood; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D015601:Injury Severity Score; D007501:Iron / Q000097:blood*; D008274:Magnesium / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013054:Spectrophotometry, Atomic; D013997:Time Factors; D014131:Trace Elements / Q000097:blood*; D055815:Young Adult; D015032:Zinc / Q000097:blood*
chemical_list: D014131:Trace Elements; D003300:Copper; D003404:Creatinine; D007501:Iron; D008274:Magnesium; D015032:Zinc