title: Health care-acquired infections in neonatal intensive care units: risk factors and etiology.
abstract: A 1-year prospective cohort study of health care-acquired infections was conducted at the neonatal intensive care unit of the University Clinical Centre Kragujevac, Serbia. The incidence rate of neonates with health care-acquired infections was 18.6%, and the incidence rate of the infections themselves was 19.4%. The incidence density of the health care-acquired infections was 9.1 per 1,000 patient days. The independent risk factors for health care-acquired infections were birth weight, length of hospitalization, duration of mechanical ventilation, and Apgar score. More than half of all isolated microorganisms were Klebsiella-Enterobacter (39.3%) and Escherichia coli (25.0%).
authors.affiliation: Epidemiology Department, Clinical Centre, Kragujevac, Serbia.
authors.forename: Zorana M
authors.initials: ZM
authors.lastname: Djordjevic
authors.affiliation: Institute of Epidemiology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Markovic-Denic
authors.affiliation: Clinical Pharmacology Department, Clinical Centre and Faculty of Medical Sciences, Kragujevac, Serbia. Electronic address: markof@medf.kg.ac.rs.
authors.forename: Marko M
authors.initials: MM
authors.lastname: Folic
authors.affiliation: Paediatric Clinic, Clinical Centre and Faculty of Medical Sciences, Kragujevac, Serbia.
authors.forename: Zoran
authors.initials: Z
authors.lastname: Igrutinovic
authors.affiliation: Clinical Pharmacology Department, Clinical Centre and Faculty of Medical Sciences, Kragujevac, Serbia.
authors.forename: Slobodan M
authors.initials: SM
authors.lastname: Jankovic
mesh_terms: D000328:Adult; D001419:Bacteria / Q000145:classification / Q000302:isolation & purification; D001424:Bacterial Infections / Q000453:epidemiology / Q000382:microbiology; D015331:Cohort Studies; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D015994:Incidence; D007363:Intensive Care Units, Neonatal; D008297:Male; D011247:Pregnancy; D011446:Prospective Studies; D012307:Risk Factors; D055771:Serbia / Q000453:epidemiology
keywords: Hospital infections; Intensive care units; Neonatal