title: Simultaneous acquisition of high-rate early, middle, and late auditory evoked potentials.
abstract: Auditory evoked potentials (AEPs) are typically acquired at rates that facilitate their study as segregated by epochs relative to stimulus onset: early (ABR, 1.5-15 ms), middle (MLR, 15-60 ms), and late (LAEP, ≥60 ms) potentials. In particular, late AEPs are often acquired with stimulus repetition rates between 0.1 Hz and 1 Hz, and are bandpass filtered to contain information only within 1-30 Hz. These low repetition rates, filtering and low SNRs eliminate much of the potential contributions of the early and middle-latency responses in AEP recordings. This study aims to demonstrate a method for acquiring whole-AEP responses at higher stimulus repetition rates of 0.5 Hz to 10 Hz, by utilizing the Continuous Loop Averaging Deconvolution (CLAD) method, increasing the bandwidth of the recordings to 1-300 Hz to include early components, and using short-duration chirps to increase synchronous firing of the cochlear and auditory pathway neurons. Such a method may facilitate diagnostic or functional assessment of single AEP recordings for detection, identification, or evaluation of early, middle and late components of auditory responses.
authors.forename: Fred D
authors.initials: FD
authors.lastname: Holt
authors.forename: Özcan
authors.initials: Ö
authors.lastname: Özdamar
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001306:Auditory Pathways / Q000502:physiology; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D008297:Male; D011930:Reaction Time; D012815:Signal Processing, Computer-Assisted; D059629:Signal-To-Noise Ratio; D055815:Young Adult