title: Proteasome inhibitor carfilzomib complements ibrutinib's action in chronic lymphocytic leukemia.
authors.affiliation: Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX.
authors.forename: Betty
authors.initials: B
authors.lastname: Lamothe
authors.affiliation: Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX.
authors.forename: Fabiola
authors.initials: F
authors.lastname: Cervantes-Gomez
authors.affiliation: Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
authors.forename: Mariela
authors.initials: M
authors.lastname: Sivina
authors.affiliation: Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
authors.forename: William G
authors.initials: WG
authors.lastname: Wierda
authors.affiliation: Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Keating
authors.affiliation: Departments of Experimental Therapeutics and Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX.
authors.forename: Varsha
authors.initials: V
authors.lastname: Gandhi
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D017209:Apoptosis / Q000187:drug effects; D015153:Blotting, Western; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D015451:Leukemia, Lymphocytic, Chronic, B-Cell; D008297:Male; D008875:Middle Aged; D009842:Oligopeptides / Q000008:administration & dosage; D010880:Piperidines; D061988:Proteasome Inhibitors / Q000008:administration & dosage; D011720:Pyrazoles / Q000008:administration & dosage; D011743:Pyrimidines / Q000008:administration & dosage; D014407:Tumor Cells, Cultured
chemical_list: D009842:Oligopeptides; D010880:Piperidines; D061988:Proteasome Inhibitors; D011720:Pyrazoles; D011743:Pyrimidines; C551803:ibrutinib; C524865:carfilzomib; D000225:Adenine