title: [Methotrexate-associated photosensitization].
abstract: BACKGROUND
  Methotrexate (MTX), alongside fumaric acid esters, is the most commonly used drug in the systemic therapy of psoriasis in Germany. It is sometimes used in combination with topical therapy and/or phototherapy due to synergistic effects.
  
  
  METHODS
  Here we describe a case of phototoxic dermatitis during treatment with MTX. Other cutaneous side effects of MTX include so-called UV recall, radiation recall, and skin tumor formation.
authors.affiliation: Klinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Hauptstraße 7, 79104, Freiburg, Deutschland, karl.hoffmann@uniklinik-freiburg.de.
authors.forename: K
authors.initials: K
authors.lastname: Hoffmann
authors.forename: F
authors.initials: F
authors.lastname: Casetti
authors.forename: C
authors.initials: C
authors.lastname: Schempp
mesh_terms: D000328:Adult; D015535:Arthritis, Psoriatic / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D009381:Neoplasms, Radiation-Induced / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000175:diagnosis* / Q000628:therapy; D011565:Psoriasis / Q000628:therapy*; D011855:Radiodermatitis / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D012307:Risk Factors; D012878:Skin Neoplasms / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D014467:Ultraviolet Therapy / Q000009:adverse effects
chemical_list: D008727:Methotrexate