title: Investigation of mosquito oviposition pheromone as lethal lure for the control of Aedes aegypti (L.) (Diptera: Culicidae).
abstract: BACKGROUND
  The trend in chemical insecticide development has focused on improving the efficacy against mosquitoes while reducing the environmental impact. Lethal lures apply an "attract-and-kill" strategy that draws the insect to the killing agent rather than bringing the killing agent to the insect.
  
  
  METHODS
  In this study, the mosquito oviposition pheromone was extracted from the eggs of Aedes aegypti (L.) and further investigated with a combination of pheromone and granular temephos as a lethal lure.
  
  
  RESULTS
  The compound caproic acid attracted significantly more egg-laying mosquitos at 1 ppm (660.83 ± 91.61) than the control (343.83 ± 56.24), which consisted of solvent only (Oviposition Activity Index: 0.316). Further investigation of the combination of caproic acid with granular temephos as a lethal lure attracted significantly more gravid female Ae. aegypti to oviposit their eggs than the temephos treated water and control.
  
  
  CONCLUSIONS
  This indicated the ability of caproic acid in acting as an attractant and counters the repellency effect of temephos. Additionally, the presence of temephos in the lethal lure also restricted the hatching of the eggs and killed any larvae that hatched.
authors.affiliation: Vector Control Research Unit, School of Biological Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia. songguan26@gmail.com.
authors.forename: Song-Quan
authors.initials: SQ
authors.lastname: Ong
authors.affiliation: Vector Control Research Unit, School of Biological Sciences, Universiti Sains Malaysia, 11800, Penang, Malaysia. zairi@usm.my.
authors.forename: Zairi
authors.initials: Z
authors.lastname: Jaal
mesh_terms: D000330:Aedes / Q000502:physiology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002208:Caproates / Q000494:pharmacology*; D005260:Female; D007306:Insecticides / Q000494:pharmacology; D009032:Mosquito Control / Q000379:methods*; D010058:Oviposition / Q000502:physiology*; D010675:Pheromones / Q000494:pharmacology*; D000002:Temefos / Q000494:pharmacology
chemical_list: D002208:Caproates; D007306:Insecticides; D010675:Pheromones; C037652:hexanoic acid; D000002:Temefos