title: Reply to Tan et al.: Differences between real and simulated proteins in multiple sequence alignments.
authors.affiliation: Conway Institute of Biomolecular and Biomedical Research and University College Dublin School of Medicine and Medical Science, University College Dublin, Dublin, Dublin 4, Ireland.
authors.forename: Kieran
authors.identifier: http://orcid.org/0000-0002-7530-2965
authors.initials: K
authors.lastname: Boyce
authors.affiliation: Conway Institute of Biomolecular and Biomedical Research and University College Dublin School of Medicine and Medical Science, University College Dublin, Dublin, Dublin 4, Ireland.
authors.forename: Fabian
authors.initials: F
authors.lastname: Sievers
authors.affiliation: Conway Institute of Biomolecular and Biomedical Research and University College Dublin School of Medicine and Medical Science, University College Dublin, Dublin, Dublin 4, Ireland des.higgins@ucd.ie.
authors.forename: Desmond G
authors.initials: DG
authors.lastname: Higgins
mesh_terms: D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment / Q000379:methods*; D020539:Sequence Analysis, Protein; D012984:Software
chemical_list: D011506:Proteins