title: Direct cross-coupling of benzyl alcohols to construct diarylmethanes via palladium catalysis.
abstract: A direct arylation to furnish diarylmethanes from benzyl alcohols was realized through Pd(PPh3)4-catalyzed Suzuki-Miyaura coupling via benzylic C-O activation in the absence of any additives. The arylation is compatible with various functional groups. This development provides an atom- and step-economic way to approach a diarylmethane scaffold under mild and environmentally benign conditions.
authors.affiliation: Beijing National Laboratory of Molecule Science (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing, 100871, China. zshi@pku.edu.cn.
authors.forename: Zhi-Chao
authors.initials: ZC
authors.lastname: Cao
authors.forename: Da-Gang
authors.initials: DG
authors.lastname: Yu
authors.forename: Ru-Yi
authors.initials: RY
authors.lastname: Zhu
authors.forename: Jiang-Bo
authors.initials: JB
authors.lastname: Wei
authors.forename: Zhang-Jie
authors.initials: ZJ
authors.lastname: Shi
mesh_terms: D001592:Benzyl Alcohols / Q000737:chemistry*; D002384:Catalysis; D008697:Methane / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D001592:Benzyl Alcohols; D009942:Organometallic Compounds; D010165:Palladium; D008697:Methane