title: Acute and chronic effects of sprint interval exercise on postprandial lipemia in women at-risk for the metabolic syndrome.
abstract: Individuals diagnosed with the metabolic syndrome (MetS) exhibit elevated postprandial lipemia (PPL). The aims of this investigation were to determine 1) if an acute bout of sprint interval training (SIT) attenuates PPL; and 2) if the attenuation of PPL following 6 wk of SIT is magnified compared with a single session of SIT prior to training in women at-risk for MetS (n = 45; 30-65 yr). Women were randomized to SIT (n = 22) or a nonexercise control (n = 23; CON) for 6 wk. Postprandial responses to a high-fat meal challenge (HFMC) were assessed in the CON group before (B-HFMC) and after (Post-HFMC) without prior exercise and in the SIT group at baseline (B-HFMC) without prior exercise, after an acute bout of SIT (four 30-s all-out sprints with 4-min recovery) prior to (Pre-HFMC), and after the 6-wk intervention (Post-HFMC). Responses to the HFMC were assessed by collecting venous blood samples in the fasted state and at 0, 30, 60, 120, and 180 min postprandial. Compared with baseline, an acute bout of SIT before (Pre-HFMC) and after the 6-wk intervention (Post-HFMC) significantly attenuated fasted TG (P < 0.05; 16.6% and 12.3%, respectively) and postprandial area under the curve (13.1% and 9.7%, respectively; tAUC) TG responses. There was no difference in fasted or tAUC TG responses between Pre-HFMC and Post-HFMC. SIT is an effective mode of exercise to reduce fasted and postprandial TG concentrations in women at-risk for MetS. Six weeks of SIT does not magnify the attenuation of PPL in response to a single session of SIT.
authors.affiliation: Department of Kinesiology, University of Georgia, Athens, Georgia; efreese2@gmail.com.
authors.forename: Eric C
authors.initials: EC
authors.lastname: Freese
authors.affiliation: Department of Kinesiology, University of Georgia, Athens, Georgia; Department of Physical Education, United States Military Academy, West Point, New York;
authors.forename: Nicholas H
authors.initials: NH
authors.lastname: Gist
authors.affiliation: Department of Kinesiology, University of Georgia, Athens, Georgia;
authors.forename: Rachelle M
authors.initials: RM
authors.lastname: Acitelli
authors.affiliation: Department of Kinesiology, University of Georgia, Athens, Georgia;
authors.forename: Whitni J
authors.initials: WJ
authors.lastname: McConnell
authors.affiliation: Department of Kinesiology, University of Georgia, Athens, Georgia;
authors.forename: Catherine D
authors.initials: CD
authors.lastname: Beck
authors.affiliation: Department of Foods and Nutrition, University of Georgia, Athens, Georgia; and.
authors.forename: Dorothy B
authors.initials: DB
authors.lastname: Hausman
authors.affiliation: Georgia Regents University, University of Georgia Medical Partnership, Athens, Georgia.
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Murrow
authors.affiliation: Department of Kinesiology, University of Georgia, Athens, Georgia;
authors.forename: Kirk J
authors.initials: KJ
authors.lastname: Cureton
authors.affiliation: Department of Kinesiology, University of Georgia, Athens, Georgia;
authors.forename: Ellen M
authors.initials: EM
authors.lastname: Evans
mesh_terms: D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000503:physiopathology* / Q000517:prevention & control*; D008137:Longitudinal Studies; D024821:Metabolic Syndrome / Q000503:physiopathology* / Q000517:prevention & control*; D008875:Middle Aged; D019518:Postprandial Period; D012307:Risk Factors; D012420:Running; D016896:Treatment Outcome
keywords: exercise training; interval exercise; meal challenge; triglycerides