title: Rhodium(III)-catalyzed C-H activation and intermolecular annulation with terminal alkynes: from indoles to carbazoles.
abstract: Herein we disclose the first example of Rh(iii)-catalyzed intermolecular annulation of indoles with terminal alkynes to give highly efficient one-pot access to privileged carbazoles. The mild reaction features moderate to good yields, exclusive regioselectivity, broad substrate scope, and excellent functional group tolerance.
authors.affiliation: VARI/SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P. R. China. yiwei.simm@simm.ac.cn eric.xu@simm.ac.cn.
authors.forename: Jinlong
authors.initials: J
authors.lastname: Jia
authors.forename: Jingjing
authors.initials: J
authors.lastname: Shi
authors.forename: Jie
authors.initials: J
authors.lastname: Zhou
authors.forename: Xuelei
authors.initials: X
authors.lastname: Liu
authors.forename: Yanling
authors.initials: Y
authors.lastname: Song
authors.forename: H Eric
authors.initials: HE
authors.lastname: Xu
authors.forename: Wei
authors.initials: W
authors.lastname: Yi
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002227:Carbazoles / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D000480:Alkynes; D002227:Carbazoles; D007211:Indoles; D002244:Carbon; D006859:Hydrogen; D012238:Rhodium