title: Tissue engineering in endodontics: root canal revascularization.
abstract: Root canal revascularization attempts to make necrotic tooth alive by the use of certain simple clinical protocols. Earlier apexification was the treatment of choice for treating and preserving immature permanent teeth that have lost pulp vitality. This procedure promoted the formation of apical barrier to seal the root canal of immature teeth and nonvital filling materials contained within root canal space. However with the success of root canal revascularization to regenerate the pulp dentin complex of necrotic immature tooth has made us to rethink if apexification is at the beginning of its end. The objective of this review is to discuss the new concepts of tissue engineering in endodontics and the clinical steps of root canal revascularization.
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Awadh Dental College and Hospital, Jamshedpur, Jharkhand, India. drmadhupalit85@gmail.com
authors.lastname: Palit Madhu Chanda
authors.forename: K Sundeep
authors.initials: KS
authors.lastname: Hegde
authors.forename: Sham S
authors.initials: SS
authors.lastname: Bhat
authors.forename: Sharan S
authors.initials: SS
authors.lastname: Sargod
authors.forename: Somasundar
authors.initials: S
authors.lastname: Mantha
authors.forename: Sayan
authors.initials: S
authors.lastname: Chattopadhyay
mesh_terms: D056624:Apexification / Q000379:methods / Q000639:trends; D003786:Dental Pulp Cavity / Q000098:blood supply* / Q000502:physiology*; D003804:Dentin / Q000502:physiology; D006801:Humans; D018919:Neovascularization, Physiologic / Q000502:physiology; D012038:Regeneration / Q000502:physiology; D012390:Root Canal Therapy / Q000379:methods*; D013234:Stem Cells / Q000502:physiology; D023822:Tissue Engineering / Q000379:methods*