title: Computational study of the influence of callus porosity on ultrasound propagation in healing bones.
abstract: In the process of fracture healing, several phases of recovery are observed as the mechanical stability, continuity and normal load carrying capacity are gradually restored. The ultrasonic monitoring and discrimination of different healing stages is a complex process due to the significant microstructure and porous nature of osseous and callus tissues. In this study, we investigate the influence of the callus pores' size and concentration on ultrasound propagation in a long bone at a late healing stage. Different excitation frequencies are applied in the range of 300 kHz-1 MHz. A 2D geometry is developed and axial transmission calculations are performed based on a Finite Element Method. The velocity of the first arriving signal (FAS) and the propagation of guided waves are used as the estimated parameters. It was shown that the FAS velocity can reflect callus porosity changes, while the propagation of guided waves is sensitive to pores' distribution for higher frequencies.
authors.forename: Vassiliki T
authors.initials: VT
authors.lastname: Potsika
authors.forename: Ioannis F
authors.initials: IF
authors.lastname: Spiridon
authors.forename: Vasilios C
authors.initials: VC
authors.lastname: Protopappas
authors.forename: Maria G
authors.initials: MG
authors.lastname: Vavva
authors.forename: Panagiotis D
authors.initials: PD
authors.lastname: Lymperopoulos
authors.forename: Christos V
authors.initials: CV
authors.lastname: Massalas
authors.forename: Demosthenes K
authors.initials: DK
authors.lastname: Polyzos
authors.forename: Dimitrios I
authors.initials: DI
authors.lastname: Fotiadis
mesh_terms: D000818:Animals; D002146:Bony Callus / Q000000981:diagnostic imaging*; D017102:Fracture Healing; D008962:Models, Theoretical; D016062:Porosity; D014463:Ultrasonography