title: Rare and persistent Rhodococcus equi infection in a diffuse large B cell lymphoma patient: case report and review of the literature.
abstract: Rhodococcus equi (R. equi) is an uncommon gram positive organism. It is a rare but recognized pathogen in humans and has emerged as an important cause of morbidity and mortality among immunocompromised patients. Generally, R. equi infection needs combined treatment with effective antibiotics, and often requires the immune adjuvant therapy. Here we reported a 49-year-old man presented dyspnea with fever, skin ulcer for 5 months, and the final diagnosis was diffuse large B cell lymphoma with R. equi septicemia and pneumonia, the treatment was failure, the blood culture was always positive during the course of disease, though he was given combined treatment with effective antibiotics, perhaps the immune reconstitution or immune supportive treatment was more important.
authors.affiliation: 1 Department of Infectious Disease, 2 Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
authors.forename: Junli
authors.initials: J
authors.lastname: Zhang
authors.affiliation: 1 Department of Infectious Disease, 2 Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Xu
authors.affiliation: 1 Department of Infectious Disease, 2 Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
authors.forename: Xiaoxing
authors.initials: X
authors.lastname: Du
authors.affiliation: 1 Department of Infectious Disease, 2 Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
authors.forename: Yunsong
authors.initials: Y
authors.lastname: Yu
authors.affiliation: 1 Department of Infectious Disease, 2 Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
authors.forename: Fangfang
authors.initials: F
authors.lastname: Lv
keywords: Rhodococcus equi (R. equi); combined treatment; diffuse large B cell lymphoma; immunologic reconstitution