title: Rhodium(III)-catalyzed C7-position C-H alkenylation and alkynylation of indolines.
abstract: A Rh(III)-catalyzed regioselective C-H alkenylation and alkynylation of indolines is described. This protocol relies on the use of a removable pyridinyl directing group to access valuable C-7 functionalized indoline scaffolds with ample substrate scope and broad functional group tolerance.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371. teckpeng@ntu.edu.sg.
authors.forename: Xiao-Fei
authors.initials: XF
authors.lastname: Yang
authors.forename: Xu-Hong
authors.initials: XH
authors.lastname: Hu
authors.forename: Chao
authors.initials: C
authors.lastname: Feng
authors.forename: Teck-Peng
authors.initials: TP
authors.lastname: Loh
mesh_terms: D002384:Catalysis; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D009942:Organometallic Compounds; C057812:indoline; D012238:Rhodium