title: Material couture for wound healing and regeneration: an overview.
abstract: Wound healing is a complex regenerative process of great importance in clinical medicine, controlled by temporal interactions between cells, extracellular matrix components and signalling molecules. Localised delivery of therapeutic active agents viz. antimicrobials, soothing minerals and/or vitamins and growth factors at the site of injury/trauma/wound are expected to be more effective and will always manifest milder toxic concerns than those observed upon systemic administration of these agents. Since ancient times, search is on for suitable materials which may restore or reproduce a favourable and a natural milieu required for skin regeneration, so as to prevent infections, and make the process fast and less painful. The journey started with the use of natural materials with a simple function of covering or dressing the wounds to more advanced materials of present times, which are designed for specific and extraordinary functions. Natural and modified or synthetic polymers; alone or in combination are commonly used as dressing (couture) materials for wound healing. This article offers a review of materials that have been used to design and develop wound dressings.
authors.forename: Indu Pal
authors.initials: IP
authors.lastname: Kaur
authors.forename: Simarjot Kaur
authors.initials: SK
authors.lastname: Sandhu
authors.forename: Parneet Kaur
authors.initials: PK
authors.lastname: Deol
authors.forename: Gaurav
authors.initials: G
authors.lastname: Sharma
authors.forename: Monika
authors.initials: M
authors.lastname: Yadav
authors.affiliation: University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, 160014, India. indupalkaur@yahoo.com.
authors.forename: Mandeep
authors.initials: M
authors.lastname: Singh
mesh_terms: D000818:Animals; D001458:Bandages; D016503:Drug Delivery Systems; D005109:Extracellular Matrix / Q000378:metabolism; D006801:Humans; D011108:Polymers / Q000737:chemistry; D012038:Regeneration / Q000502:physiology*; D012867:Skin / Q000378:metabolism; D014945:Wound Healing / Q000502:physiology*
chemical_list: D011108:Polymers