title: Recurrent polymyositis-associated lung disease after lung transplantation.
abstract: The association between interstitial lung disease and polymyositis/dermatomyositis is well known. It severely affects patients' quality of life, worsens prognosis and represents a major risk factor for premature death. Current treatment is unclear and therapeutic options are based on case series. We report the case of a 15-year old female diagnosed with end-stage lung disease associated to polymyositis who received a double lung transplant after 20 days of extracorporeal membrane oxygenation. She died 9 months later and microscopic post-mortem findings revealed recurrence of interstitial lung disease. This is the first time that recurrence of polymyositis-associated lung disease following lung transplantation is described in the literature.
authors.affiliation: Department of Anaesthesia, Hospital '12 de Octubre', Madrid, Spain rarboleda@salud.aragon.es.
authors.forename: Rafael
authors.initials: R
authors.lastname: Arboleda
authors.affiliation: Department of Anaesthesia, Hospital '12 de Octubre', Madrid, Spain.
authors.forename: Olga
authors.initials: O
authors.lastname: Gonzalez
authors.affiliation: Department of Anaesthesia, Hospital '12 de Octubre', Madrid, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Cortes
authors.affiliation: Department of Anaesthesia, Hospital '12 de Octubre', Madrid, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Perez-Cerda
mesh_terms: D000293:Adolescent; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D016040:Lung Transplantation / Q000009:adverse effects*; D017285:Polymyositis / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D012008:Recurrence; D013997:Time Factors; D014057:Tomography, X-Ray Computed
keywords: Extracorporeal membrane oxygenation; Lung transplantation; Polymyositis; Pulmonary fibrosis