title: Polioencephalomyelopathy in a mixed breed dog resembling Leigh's disease.
abstract: A 14-month-old mixed-breed dog was presented with acute onset of exercise intolerance that quickly progressed to quadriparesis. Gross and microscopic autopsy findings indicated a type of degenerative polioencephalomyelopathy resembling subacute necrotizing encephalomyelopathy in dogs or Leigh's disease in humans. This syndrome has previously been reported only in purebred dogs.
authors.affiliation: Veterinary Teaching Hospital, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel (Chai, Milgram, Shamir); Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel (Brenner).
authors.forename: Orit
authors.initials: O
authors.lastname: Chai
authors.affiliation: Veterinary Teaching Hospital, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel (Chai, Milgram, Shamir); Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel (Brenner).
authors.forename: Joshua
authors.initials: J
authors.lastname: Milgram
authors.affiliation: Veterinary Teaching Hospital, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel (Chai, Milgram, Shamir); Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel (Brenner).
authors.forename: Merav H
authors.initials: MH
authors.lastname: Shamir
authors.affiliation: Veterinary Teaching Hospital, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, PO Box 12, Rehovot 76100, Israel (Chai, Milgram, Shamir); Weizmann Institute of Science, PO Box 26, Rehovot 76100, Israel (Brenner).
authors.forename: Ori
authors.initials: O
authors.lastname: Brenner
mesh_terms: D000818:Animals; D020739:Brain Diseases, Metabolic, Inborn / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D005260:Female