title: Resting-state networks in healthy adult subjects: a comparison between a 32-element and an 8-element phased array head coil at 3.0 Tesla.
abstract: BACKGROUND
  Little research exists on the influence of a magnetic resonance imaging (MRI) head coil's channel count on measured resting-state functional connectivity.
  
  
  OBJECTIVE
  To compare a 32-element (32ch) and an 8-element (8ch) phased array head coil with respect to their potential to detect functional connectivity within resting-state networks.
  
  
  METHODS
  Twenty-six healthy adults (mean age, 21.7 years; SD, 2.1 years) underwent resting-state functional MRI at 3.0 Tesla with both coils using equal standard imaging parameters and a counterbalanced design. Independent component analysis (ICA) at different model orders and a dual regression approach were performed. Voxel-wise non-parametric statistical between-group contrasts were determined using permutation-based non-parametric inference.
  
  
  RESULTS
  Phantom measurements demonstrated a generally higher image signal-to-noise ratio using the 32ch head coil. However, the results showed no significant differences between corresponding resting-state networks derived from both coils (p < 0.05, FWE-corrected).
  
  
  CONCLUSIONS
  Using the identical standard acquisition parameters, the 32ch head coil does not offer any significant advantages in detecting ICA-based functional connectivity within RSNs.
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Munich, Germany marco.paolini@med.uni-muenchen.de.
authors.forename: Marco
authors.initials: M
authors.lastname: Paolini
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Munich, Germany Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University, Munich, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Keeser
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Munich, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Ingrisch
authors.affiliation: Department of Psychology, Ludwig-Maximilians-University, Munich, Germany.
authors.forename: Natalie
authors.initials: N
authors.lastname: Werner
authors.affiliation: Department of Psychology, Ludwig-Maximilians-University, Munich, Germany.
authors.forename: Nicole
authors.initials: N
authors.lastname: Kindermann
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Munich, Germany.
authors.forename: Maximilian
authors.initials: M
authors.lastname: Reiser
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Munich, Germany.
authors.forename: Janusch
authors.initials: J
authors.lastname: Blautzik
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000033:anatomy & histology*; D001931:Brain Mapping / Q000379:methods*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods*; D008297:Male; D019047:Phantoms, Imaging; D012016:Reference Values; D012146:Rest; D059629:Signal-To-Noise Ratio; D055815:Young Adult
keywords: CNS; equipment; functional connectivity; magnetic resonance functional imaging; phantom study; signal-to-noise ratio