title: Statin utilisation patterns in older Australians living in residential care: 1-year prevalence study.
abstract: Despite controversy over the risks and benefits of statin therapy, statins continue to be commonly used medicines by older people. In a cohort study of participants aged ≥70 years (n = 540) living in residential care, Sydney, we found that the proportion of statin users decreased gradually from the baseline of 33.1% to 31.3% at 6 months (P = 0.13) and to 28.7% over 1 year (P = 0.002). Prevalence of statin use decreased with increasing age, with individuals aged ≥90 years being more likely to discontinue or deprescribe statins. The patterns of statin use did not change according to increasing baseline dose or baseline indication.
authors.affiliation: Faculty of Pharmacy, Sydney Medical School, Sydney, New South Wales, Australia; Royal North Shore Hospital and Kolling Institute of Medical Research, Sydney Medical School, Sydney, New South Wales, Australia.
authors.forename: D
authors.initials: D
authors.lastname: Gnjidic
authors.forename: N
authors.initials: N
authors.lastname: Wilson
authors.forename: L
authors.initials: L
authors.lastname: March
authors.forename: R G
authors.initials: RG
authors.lastname: Cumming
authors.forename: I D
authors.initials: ID
authors.lastname: Cameron
authors.forename: S N
authors.initials: SN
authors.lastname: Hilmer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001315:Australia / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D015995:Prevalence; D012307:Risk Factors
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors
keywords: deprescribing; limited life expectancy; older people; residential care; statin