title: Living donor liver transplantation using a graft with periportal fibrosis.
abstract: A 57-year-old woman with familial amyloid polyneuropathy (FAP) was scheduled to undergo living donor liver transplantation (LDLT), but the operation was cancelled because the only potential donor had chronic alcohol-related liver disease. One year later, FAP-related neurological symptoms progressed rapidly, and emergency LDLT was planned. The donor's hepatic function had returned to normal range after 1 year of abstinence. The left liver graft volume was equivalent to 37.7% of the standard liver volume (SLV) of the recipient. However, a liver biopsy revealed mild fibrosis (score, F1). LDLT was successfully performed without any complications. The recipient's neurological findings returned to normal. One year after LDLT, the liver graft volume was equivalent to approximately 90% of the SLV, and the fibrosis had improved. LDLT using a graft with a fibrosis score of up to F1 may be an acceptable alternative for recipients with normal hepatic function.
authors.affiliation: Department of Hepato-Biliary-Pancreatic-Transplantation Surgery, Japanese Red Cross Medical Center, Tokyo, Japan.|Third Department of Medicine, Shinshu University School of Medicine, Shinshu, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Mitsuka
authors.affiliation: Department of Hepato-Biliary-Pancreatic-Transplantation Surgery, Japanese Red Cross Medical Center, Tokyo, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Hashimoto
authors.affiliation: Department of Hepato-Biliary-Pancreatic-Transplantation Surgery, Japanese Red Cross Medical Center, Tokyo, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Takamoto
authors.affiliation: Department of Hepato-Biliary-Pancreatic-Transplantation Surgery, Japanese Red Cross Medical Center, Tokyo, Japan.
authors.forename: Kazuto
authors.initials: K
authors.lastname: Inoue
authors.affiliation: Department of Hepato-Biliary-Pancreatic-Transplantation Surgery, Japanese Red Cross Medical Center, Tokyo, Japan.
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Maruyama
authors.affiliation: Department of Hepato-Biliary-Pancreatic-Transplantation Surgery, Japanese Red Cross Medical Center, Tokyo, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ogata
authors.affiliation: Department of Digestive Surgery, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: Michiharu
authors.initials: M
authors.lastname: Komatsu
authors.affiliation: Department of Digestive Surgery, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: Shu-Ichi
authors.initials: S
authors.lastname: Ikeda
authors.affiliation: Third Department of Medicine, Shinshu University School of Medicine, Shinshu, Japan.
authors.forename: Tadatoshi
authors.initials: T
authors.lastname: Takayama
authors.affiliation: Department of Hepato-Biliary-Pancreatic-Transplantation Surgery, Japanese Red Cross Medical Center, Tokyo, Japan.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Makuuchi
keywords: donor criteria; fibrosis; live donor