title: Implementation of a microfluidic conductivity sensor -- a potential sweat electrolyte sensing system for dehydration detection.
abstract: As dehydration continues to plague performance athletes and soldiers, the need for improved dehydration detection is clear. We propose the use of a conductometric sensor as the foundation of a sweat-sensing patch to address this need. The conductometric sensor evaluates the conductivity of solutions with varying sodium concentrations. A lithographic process was used to fabricate a Polydimethylsiloxane (PDMS) microfluidic channel through which solution was flowed. The ionization of the solution that occurs when a voltage is applied results in an effective resistance across the channel. The measured resistance therefore, reflects the ionization of the solution and the corresponding sodium concentration. The potential application of the conductometric sensor in a sweat-sensing patch requires compatibility with a microcontroller and Bluetooth module. Thus, a circuit interface was created. A voltage divider was utilized to convert the output resistance of the sensor to a voltage that could be input into a microcontroller. An AC voltage signal with a frequency of 10 kHz was used as the source voltage of the voltage divider to minimize the faradaic impedance and the double layer effect of the ionized solution. Tests have revealed that the conductometric is capable of precisely measuring the conductivity of a sodium solution. The conductometric sensor will be applied to a sweat sensing patch through future work involving studying the link between sodium concentration in sweat and an individual's dehydration level, developing a sweat-collection method, and developing a method of consideration for the other ions contained in sweat.
authors.lastname: Gengchen Liu
authors.forename: Kyle
authors.initials: K
authors.lastname: Smith
authors.forename: Tolga
authors.initials: T
authors.lastname: Kaya
mesh_terms: D003681:Dehydration; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D004553:Electric Conductivity; D004573:Electrolytes / Q000737:chemistry*; D006801:Humans; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D012964:Sodium / Q000032:analysis*; D013542:Sweat / Q000737:chemistry
chemical_list: D004129:Dimethylpolysiloxanes; D004573:Electrolytes; C013830:baysilon; D012964:Sodium