title: A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy.
abstract: The combination chemotherapy of irinotecan with 5-fluorouracil and leucovorin (FOLFIRI regimen) was recently proven to be beneficial in patients with advanced colorectal cancer. Pulmonary toxicity is very rare in adverse effects of irinotecan. No case of organizing pneumonia (also known as bronchiolitis obliterans organizing pneumonia) associated with FOLFIRI chemotherapy has been reported. We experienced a case of a 62-year-old man who presented persistent dry cough and progressive dyspnea after receiving chemotherapy with FOLFIRI regimen. After surgical lung biopsy, the patient was diagnosed with FOLFIRI chemotherapy-induced organizing pneumonia which was successfully treated with steroid therapy.
authors.affiliation: Department of Internal Medicine, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Yoon Jeong
authors.initials: YJ
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Jun-Hyun
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Sun Woong
authors.initials: SW
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Won Chan
authors.initials: WC
authors.lastname: Kang
authors.affiliation: Department of Internal Medicine, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Soo Jung
authors.initials: SJ
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Ji Hye
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, Korea.
authors.forename: Sun Jong
authors.initials: SJ
authors.lastname: Kim
keywords: Colorectal Neoplasmsoxaliplatin; Cryptogenic Organizing Pneumonia; IFL Protocol; Irinotecan