title: The Effect of Sumac (Rhus coriaria L.)Powder on Serum Glycemic Status, ApoB, ApoA-I and Total Antioxidant Capacity in Type 2 Diabetic Patients.
abstract: Sumac (Rhus coriaria L.) is used as an herbal remedy in traditional medicine. The aim of this study was to determine the effects of sumac (R. coriaria) on serum glycemic status, apolipoprotein (apo) B, apoA-I and total antioxidant capacity (TAC) in type 2 diabetic patients. This double blind randomized controlled clinical trial was conducted on 41type 2 diabetic volunteers randomly assigned into 3g/day sumac powder (n=22) or placebo (n=19) groups over 3 months. Blood samples were collected before and after the intervention. Serum glucose and HbA1c were measured using enzymatic and turbidimetric inhibition immunoassay methods, respectively. ApoB, apoA-I and TAC were determined using turbidimetric immunoassay and spectrophotometric methods, respectively. There were signiﬁcant decreases in serum glucose and HbA1c and also apoB levels at the end of study compared with initial values (P< 0.0001, P= 0.002 and P< 0.0001,respectively). Also, there was a significant difference in HbA1c and TAC levels between placebo and sumac groups at the end of study (P< 0.05).In sumac group, there were significant increase in apoA-I and TAC(P< 0.0001) compared with initial values. The mean of differences of serum glucose, HbA1c, apoB, apoA-I, apoB/apoA-I ratio and TAC between groups were significant (P< 0.05). In conclusion, these results showed the favorite effect of sumac consumption on serum glycemic status, apoB, apoA-I and TAC levels in in type 2 diabetic patients.
authors.affiliation: Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Farzad
authors.initials: F
authors.lastname: Shidfar
authors.affiliation: Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Seyedeh Tayebeh
authors.initials: ST
authors.lastname: Rahideh
authors.affiliation: Iranian Diabetes Association, Tehran, Iran.
authors.forename: Asadollah
authors.initials: A
authors.lastname: Rajab
authors.affiliation: Research Institute for Islamic and Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Nafise
authors.initials: N
authors.lastname: Khandozi
authors.affiliation: Islamic Azad University, Robat Karim Branch, Robat Karim, Iran.
authors.forename: Sharieh
authors.initials: S
authors.lastname: Hosseini
authors.affiliation: University of Massachusetts, Worcester Memorial Hospital, Worcester, Massachusetts, USA.
authors.forename: Shahrzad
authors.initials: S
authors.lastname: Shidfar
authors.affiliation: School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Faraz
authors.initials: F
authors.lastname: Mojab
keywords: Apolipoprotein; Diabetes; Glycemic status; Sumac; Total antioxidant capacity