title: Psychometric validation of the Brain Symptom and Impact Questionnaire (BASIQ) version 1.0 to assess quality of life in patients with brain metastases.
abstract: OBJECTIVE
  To test the reliability, clinical and psychometric validity of the Brain Symptom and Impact Questionnaire (BASIQ) in patients with brain metastases.
  
  
  METHODS
  Brain metastases patients were interviewed using the BASIQ, Functional Assessment of Cancer-Brain (FACT-Br) and FACT-General (FACT-G) at baseline, with a follow-up assessment at 1 month.
  
  
  RESULTS
  Forty patients had complete one data and the median age was 64 years. Patients with higher KPS, ECOG of 2, primary breast cancer, or >3 brain metastases, scored higher on the symptom scale of the BASIQ. All subscales showed no significant change in patient symptoms from baseline to follow-up.
  
  
  CONCLUSIONS
  This study supports that the reliability, clinical and psychometric validity of BASIQ to be used in brain metastases patients.
authors.affiliation: Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, M4N3M5 Canada.
authors.forename: Nemica
authors.initials: N
authors.lastname: Thavarajah
authors.forename: Saurabh
authors.initials: S
authors.lastname: Ray
authors.forename: Gillian
authors.initials: G
authors.lastname: Bedard
authors.forename: Liying
authors.initials: L
authors.lastname: Zhang
authors.forename: David
authors.initials: D
authors.lastname: Cella
authors.forename: Erin
authors.initials: E
authors.lastname: Wong
authors.forename: Cyril
authors.initials: C
authors.lastname: Danjoux
authors.forename: May
authors.initials: M
authors.lastname: Tsao
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Barnes
authors.forename: Arjun
authors.initials: A
authors.lastname: Sahgal
authors.forename: Hany
authors.initials: H
authors.lastname: Soliman
authors.forename: Natalie
authors.initials: N
authors.lastname: Pulenzas
authors.forename: Breanne
authors.initials: B
authors.lastname: Lechner
authors.forename: Edward
authors.initials: E
authors.lastname: Chow
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000503:physiopathology; D001932:Brain Neoplasms / Q000150:complications* / Q000523:psychology* / Q000556:secondary; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011594:Psychometrics / Q000379:methods*; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D013997:Time Factors
keywords: BASIQ; brain metastases; field-testing; psychometric validation; quality of life; questionnaire