title: Predictive model of oral cancer metastasis for different cancer sites and age groups.
abstract: OBJECTIVE
  The high incidence rates for oral cancer (excluding lip) are especially found in the South and South-East Asia. Therefore, the aim of the present study was to investigate the relationship between sex, age, site, and metastasis of a large sample with oral squamous cell carcinoma (OSCC).
  
  
  METHODS
  A total of 989 OSCC treated with neck dissection were selected. All the relevant data were recorded from biopsy request forms. The patients were divided into seven groups, and there were nine different oral sites.
  
  
  RESULTS
  The male-to-female ratio of the sample was 4:1. Most of the patients were aged between 30 and 60 years. Of the 989 patients, approximately 40% patients had metastasis. Age <30 years showed a higher probability of metastasis compared to higher age groups, but it was not statistically significant. Palate cancers had more than 14 times higher chance of metastasis, followed by maxilla (4.6 times) and tongue (2.8 times).
  
  
  CONCLUSIONS
  The present study provides important information on the metastatic potential of OSCC in different oral sites, and identifies high-risk age groups for metastasis. This will be helpful in planning neck treatment for OSCC.
authors.affiliation: Department of Oral Pathology, Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka.
authors.forename: Bogahawatte Samarakoon Mudiyanselage Samadarani
authors.initials: BS
authors.lastname: Siriwardena
authors.affiliation: Department of Oral Pathology, Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka.
authors.forename: Rasnayaka Mudiynaselage Sumudu Geethika Kumari
authors.initials: RM
authors.lastname: Rasnayaka
authors.affiliation: Department of Oral Pathology, Faculty of Dentistry, Universiti Teknologi MARA, Selangor, Malaysia.
authors.forename: Yaghma
authors.initials: Y
authors.lastname: Masood
authors.affiliation: Department of Oral Pathology, Faculty of Dentistry, Universiti Teknologi MARA, Selangor, Malaysia.
authors.forename: Mohd
authors.initials: M
authors.lastname: Masood
authors.affiliation: Department of Community Medicine, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
authors.forename: Pallegoda Vithanage Ranjith
authors.initials: PV
authors.lastname: Kumarasiri
authors.affiliation: Department of Oral Pathology, Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka.
authors.forename: Wanninayake Mudiyanselage
authors.initials: WM
authors.lastname: Tilakaratne
mesh_terms: D000328:Adult; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000556:secondary*; D005260:Female; D006801:Humans; D008048:Lip Neoplasms / Q000556:secondary*; D008297:Male; D009062:Mouth Neoplasms / Q000473:pathology*; D037981:Neck Dissection; D009362:Neoplasm Metastasis; D012189:Retrospective Studies
keywords: age; metastasis; oral cancer; predictive model; site