title: [Prevalence and risk factors of multi-drug resistant organism colonization among long-term care facilities in Gran Canaria (Spain)].
abstract: BACKGROUND
  Multidrug resistant organisms (MDRO) are an important cause of nosocomial infections, with complicated clinical-therapeutic management and elevated morbidity-mortality, and an increase in healthcare costs. In long term care facilities (LTCFs) colonization/infection by MDRO among residents is increasing, and they may act as reservoirs and vehicles for the dissemination and production of outbreaks by resistant strains in acute hospitals. This study aimed at determining the prevalence of carriers of some common MDRO, and identifying factors associated with carrier state.
  
  
  METHODS
  A cross-sectional prevalence study was conducted on 235 residents in two LTCFs in the province of Las Palmas de Gran Canaria (Canary Islands, Spain) between October and November of 2012. The presence of MMR was investigated in nasal, pharyngeal and rectal swabs using selective media. Risk factors associated with carrier state were calculated using univariate and multivariate analysis.
  
  
  RESULTS
  More than one-third (36.2%) of residents were found to be carriers of ≥ 1 distinct MDROs. More than one-quarter (26.6%) were carriers of ESBL producing Enterobacteriaceae, and 10.2% were MRSA carriers. Factors found to be associated with colonization by any MDRO were: prior colonization or infection by MDRO, hospitalization in the past 3 months, recurrent infections of the urinary tract, and peripheral arterial disease.
  
  
  CONCLUSIONS
  The prevalence of MDRO in the LTCFs settings studied is greater than that found in the literature, and in particular ESBL producing Enterobacteriaceae. Due to the high prevalence of infection/colonization by MDRO, it is possible that residents of LTCFs could act as important reservoirs of MDRO, and facilitate their spread into the acute care setting.
authors.affiliation: Servicio de Microbiología, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, España. Electronic address: cristobaldelrosario@gmail.com.
authors.forename: Cristóbal
authors.initials: C
authors.lastname: Del Rosario-Quintana
authors.affiliation: Servicio de Microbiología, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, España.
authors.forename: Tomás
authors.initials: T
authors.lastname: Tosco-Núñez
authors.affiliation: Servicio de Microbiología, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, España.
authors.forename: Leticia
authors.initials: L
authors.lastname: Lorenzo
authors.affiliation: Servicio de Microbiología, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, España.
authors.forename: Antonio Manuel
authors.initials: AM
authors.lastname: Martín-Sánchez
authors.affiliation: Servicio de Medicina Preventiva, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, España.
authors.forename: Jesús
authors.initials: J
authors.lastname: Molina-Cabrillana
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002353:Carrier State / Q000453:epidemiology* / Q000382:microbiology*; D003430:Cross-Sectional Studies; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006268:Health Facilities; D006801:Humans; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D013030:Spain
keywords: Betalactamasas de espectro extendido; Centro de larga estancia; Extended spectrum Beta lactamase; Long term-care facilities; Methicillin-resistant Staphylococcus aureus; Microorganismo multirresistente; Multidrug Resistant Organism; Prevalence; Prevalencia; Staphylococcus aureus resistente a meticilina