title: Identification of antibacterial and antioxidant constituents of the essential oils of Cynanchum chinense and Ligustrum compactum.
abstract: The aim of this research was to determine the chemical composition, antioxidant and antibacterial properties of the essential oils from Cynanchum chinense and Ligustrum compactum and isolation of antioxidant and antibacterial constituents from the essential oils. Thirty-eight components were identified in essential oils. Based on bioactivity-guided fractionation, guaiacol, linalool and 2-phenylethanol were isolated and identified as active constituents. Both L. compactum flower oil and 2-phenylethanol showed high antibacterial performance, with inhibition zone from 22.8 ± 0.8 to 11.9 ± 2.0 mm at highest concentration, and minimum inhibitory concentration values ranging from 0.25% to 1%. In both DPPH and ABTS assay, the active constituent guaiacol (IC50 = 4.15 ± 0.72 and 9.12 ± 0.98 μg mL(-1), respectively) exhibited high antioxidant activity, and the oils showed moderate antioxidant activity. These results indicate potential efficacy of active constituents and essential oils of L. compactum and C. chinense to control food-borne pathogenic and spoilage bacteria.
authors.affiliation: a The First Affiliated Hospital, Changchun University of Chinese Medicine , Changchun, Jilin 130021 , P.R. China.
authors.forename: Lan
authors.initials: L
authors.lastname: Yu
authors.forename: Ji-Xiang
authors.initials: JX
authors.lastname: Ren
authors.forename: Hong-Mei
authors.initials: HM
authors.lastname: Nan
authors.forename: Bao-Feng
authors.initials: BF
authors.lastname: Liu
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects; D031105:Cynanchum / Q000737:chemistry*; D035264:Flowers / Q000737:chemistry; D031659:Ligustrum / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000975:Antioxidants; D009822:Oils, Volatile; D010938:Plant Oils
keywords: active constituents; bioassay-directed fractionation; chemical composition