title: A rare case of jejuno-ileal intussusception secondary to a gastrointestinal stromal tumour.
abstract: Gastrointestinal stromal tumours (GISTs) are rare tumours, making up 0.2-1% of gastrointestinal malignancies [Zakaria and Daradkeh (Jejunojejunal intussusception induced by a gastrointestinal stromal tumour. Case Rep Surg 2012; 2022: :173680)]. Their relative rarity combined with non-specific presentation results in tumours often remaining undiagnosed until surgery or histological examination [Martis et al. (A rare case of jejunojejunal intussusception in an adult. Indian J Surg 2013; 75: (Suppl 1):18-20)]. Presentation as a lead point for intussusception is particularly rare. We present the first case of GIST leading to intussusception at the jejuno-ileal junction in an otherwise well patient prior to presentation. Provisional diagnosis was made during emergency laparotomy, and confirmed through histological analysis. A typical immunohistochemical profile was identified, after which the patient was commenced on adjuvant imatinib therapy. We discuss classical presentation of intussusception and GIST. Further considerations of the investigation and treatment options of GISTs are also presented.
authors.affiliation: Colorectal Department, New Cross Hospital, Wolverhampton, West Midlands, UK annabel.stout@nhs.net.
authors.forename: Annabel
authors.initials: A
authors.lastname: Stout
authors.affiliation: Colorectal Department, New Cross Hospital, Wolverhampton, West Midlands, UK.
authors.forename: Lakshmi
authors.initials: L
authors.lastname: Santharam
authors.affiliation: Colorectal Department, New Cross Hospital, Wolverhampton, West Midlands, UK.
authors.forename: Nazzia
authors.initials: N
authors.lastname: Mirza