title: Synthesis and preservative application of quaternized carboxymethyl chitosan containing guanidine groups.
abstract: A chitosan derivative, quaternized carboxymethyl chitosan containing guanidine groups (QGCMC), was synthesized and structurally characterized using FT-IR, (1)H NMR spectroscopy. The elemental composition of QGCMC was also investigated. Increase in the molar ratio of materials used for QGCMC synthesis and an increase in the reaction time of QGCMC synthesis led to an increased degree of substitution. QGCMC demonstrated a strong antimicrobial activity at acidic, neutral, and basic pH conditions and could significantly lengthen the shelf life of strawberries.
authors.affiliation: School of Chemical Engineering, Changzhou University, Changzhou 213614, PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Sang
authors.affiliation: School of Chemical and Biological Engineering, Yancheng Institute of Technology, Yancheng 224051, PR China.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Tang
authors.affiliation: School of Chemical Engineering, Changzhou University, Changzhou 213614, PR China.
authors.forename: Ming-Yang
authors.initials: MY
authors.lastname: He
authors.affiliation: School of Chemical and Biological Engineering, Yancheng Institute of Technology, Yancheng 224051, PR China.
authors.forename: Yong-Pei
authors.initials: YP
authors.lastname: Hua
authors.affiliation: School of Chemical and Biological Engineering, Yancheng Institute of Technology, Yancheng 224051, PR China. Electronic address: xqsteve@ycit.cn.
authors.forename: Qi
authors.initials: Q
authors.lastname: Xu
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D048271:Chitosan / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D005520:Food Preservatives / Q000494:pharmacology*; D031985:Fragaria / Q000187:drug effects; D019791:Guanidine / Q000737:chemistry*; D006146:Guanidines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D008826:Microbial Sensitivity Tests; D008855:Microscopy, Electron, Scanning; D066244:Proton Magnetic Resonance Spectroscopy; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D005520:Food Preservatives; D006146:Guanidines; C514968:carboxymethyl-chitosan; D048271:Chitosan; D019791:Guanidine
keywords: Carboxymethyl chitosan; Guanidine group; Preservative coating