title: Does food insufficiency in childhood contribute to dementia in later life?
abstract: BACKGROUND
  Despite several studies attempting to identify the risk factors for dementia, little is known about the impact of childhood living conditions on cognitive function in later life. The present study aims to examine the unique contribution of food insufficiency in childhood to dementia in old age.
  
  
  METHODS
  Data for this study of 2,745 older Malaysians aged 60 years and older was obtained from a national survey entitled "Mental Health and Quality of Life of Older Malaysians" conducted from 2003 through 2005 using a cross-sectional design. The Geriatric Mental State-Automated Geriatric Examination for Computer Assisted Taxonomy was used to measure dementia. A multiple binary logistic regression using Statistical Package for Social Sciences version 21 was conducted to assess the unique effect of food insufficiency in childhood on developing dementia in old age.
  
  
  RESULTS
  A notably higher prevalence of dementia was found in respondents who indicated they had experienced food insufficiency in childhood than in their food-sufficient counterparts (23.5% versus 14.3%). The findings from multiple logistic regression analysis revealed that food insufficiency in childhood would independently increase the risk of developing dementia in old age by 81%, after adjusting for sociodemographic factors (odds ratio =1.81, 95% confidence interval 1.13-2.92, P<0.01).
  
  
  CONCLUSIONS
  Findings from the present study showing that food insufficiency in early life significantly contributes to dementia in later life highlight the importance of childhood living conditions in maintaining cognitive function in old age. It is, therefore, suggested that older adults with childhood food insufficiency might be targeted for programs designed to prevent dementia.
authors.affiliation: Institute of Gerontology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia ; Iranian Research Center on Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
authors.forename: Yadollah Abolfathi
authors.initials: YA
authors.lastname: Momtaz
authors.affiliation: Institute of Gerontology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia ; Department of Resource Management and Consumer Studies, Faculty of Human Ecology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
authors.forename: Sharifah Azizah
authors.initials: SA
authors.lastname: Haron
authors.affiliation: Institute of Gerontology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia ; Department of Human Development and Family Studies, Faculty of Human Ecology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
authors.forename: Tengku Aizan
authors.initials: TA
authors.lastname: Hamid
authors.affiliation: Institute of Gerontology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia ; Department of Human Development and Family Studies, Faculty of Human Ecology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
authors.forename: Rahimah
authors.initials: R
authors.lastname: Ibrahim
authors.affiliation: Institute of Gerontology, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
authors.forename: Jariah
authors.initials: J
authors.lastname: Masud
mesh_terms: D000367:Age Factors; D000368:Aged; D002648:Child; D015362:Child Nutrition Disorders / Q000150:complications / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003704:Dementia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D007361:Intelligence Tests; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012924:Social Conditions / Q000706:statistics & numerical data; D012959:Socioeconomic Factors; D013995:Time
keywords: Malaysia; aged; dementia; food insufficiency