title: Blind deconvolution in dynamic contrast-enhanced MRI and ultrasound.
abstract: This paper is focused on quantitative perfusion analysis using MRI and ultrasound. In both MRI and ultrasound, most approaches allow estimation of rate constants (Ktrans, kep for MRI) and indices (AUC, TTP) that are only related to the physiological perfusion parameters of a tissue (e.g. blood flow, vessel permeability) but do not allow their absolute quantification. Recent methods for quantification of these physiological perfusion parameters are shortly reviewed. The main problem of these methods is estimation of the arterial input function (AIF). This paper summarizes and extends the current blind-deconvolution approaches to AIF estimation. The feasibility of these methods is shown on a small preclinical study using both MRI and ultrasound.
authors.forename: Radovan
authors.initials: R
authors.lastname: Jiřík
authors.forename: Karel
authors.initials: K
authors.lastname: Souček
authors.forename: Martin
authors.initials: M
authors.lastname: Mézl
authors.forename: Michal
authors.initials: M
authors.lastname: Bartoš
authors.forename: Eva
authors.initials: E
authors.lastname: Dražanová
authors.forename: František
authors.initials: F
authors.lastname: Dráfi
authors.forename: Lucie
authors.initials: L
authors.lastname: Grossová
authors.forename: Jiří
authors.initials: J
authors.lastname: Kratochvíla
authors.forename: Ondřej
authors.initials: O
authors.lastname: Macíček
authors.forename: Kim
authors.initials: K
authors.lastname: Nylund
authors.forename: Aleš
authors.initials: A
authors.lastname: Hampl
authors.forename: Odd Helge
authors.initials: OH
authors.lastname: Gilja
authors.forename: Torfinn
authors.initials: T
authors.lastname: Taxt
authors.forename: Zenon
authors.initials: Z
authors.lastname: Starčuk
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D003287:Contrast Media / Q000493:pharmacokinetics*; D019786:Gadolinium DTPA / Q000493:pharmacokinetics*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000000981:diagnostic imaging / Q000378:metabolism; D014018:Tissue Distribution; D014463:Ultrasonography
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA