title: Looking into Candida albicans infection, host response, and antifungal strategies.
abstract: Candida albicans, a commonly encountered fungal pathogen, causes diseases varying from superficial mucosal complaints to life-threatening systemic disorders. Among the virulence traits of C. albicans, yeast-to-hypha transition is most widely acknowledged. Host innate immunity to C. albicans critically requires pattern recognition receptors (PRRs), and defence against C. albicans infection is provided by an exquisite interplay between the innate and adaptive arms of the host immune system.
authors.affiliation: a New Drug Research and Development Center; School of Pharmacy ; Second Military Medical University ; Shanghai , China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
mesh_terms: D056704:Adaptive Immunity; D002176:Candida albicans / Q000276:immunology* / Q000472:pathogenicity* / Q000502:physiology; D002177:Candidiasis / Q000276:immunology* / Q000382:microbiology; D005657:Fungal Vaccines; D054884:Host-Pathogen Interactions; D006801:Humans; D007113:Immunity, Innate
chemical_list: D005657:Fungal Vaccines
keywords: Candida albicans; antifungal; immune response