title: Recombinant protein (EGFP-Protein G)-coated PbS quantum dots for in vitro and in vivo dual fluorescence (visible and second-NIR) imaging of breast tumors.
abstract: We report a one-step synthetic strategy for the preparation of recombinant protein (EGFP-Protein G)-coated PbS quantum dots for dual (visible and second-NIR) fluorescence imaging of breast tumors at the cellular and whole-body level.
authors.affiliation: Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki 305-8566, Japan. akira.sasaki@aist.go.jp.
authors.forename: Akira
authors.initials: A
authors.lastname: Sasaki
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Tsukasaki
authors.forename: Akihito
authors.initials: A
authors.lastname: Komatsuzaki
authors.forename: Takao
authors.initials: T
authors.lastname: Sakata
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Yasuda
authors.forename: Takashi
authors.initials: T
authors.lastname: Jin
mesh_terms: D000818:Animals; D001943:Breast Neoplasms / Q000378:metabolism* / Q000473:pathology*; D045744:Cell Line, Tumor; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis; D049452:Green Fluorescent Proteins / Q000737:chemistry* / Q000235:genetics; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007259:Infrared Rays; D007854:Lead / Q000737:chemistry* / Q000528:radiation effects; D051379:Mice; D008819:Mice, Nude; D036641:Microscopy, Fluorescence, Multiphoton / Q000379:methods*; D045663:Quantum Dots; D011994:Recombinant Proteins / Q000493:pharmacokinetics; D015203:Reproducibility of Results; D018036:Selenium Compounds / Q000737:chemistry* / Q000528:radiation effects; D012680:Sensitivity and Specificity; D051598:Whole Body Imaging / Q000379:methods
chemical_list: D020099:Coated Materials, Biocompatible; D011994:Recombinant Proteins; D018036:Selenium Compounds; C485184:enhanced green fluorescent protein; C088065:lead selenide; D049452:Green Fluorescent Proteins; D007854:Lead