title: [Studies regarding the fixing of the zinc from ADH through some azopyrazolone].
abstract: The mechanism of reaction-between the zinc atom of alcohol dehydrogenase and 6 pyrazolone and azopyrazolone compounds, type 1-(4'-carboxyphenyl)-3-methyl-4(1"azo-4"-ethoxy-phenyl)-5-pyrazolone, synthetized by the authors, is studied. For elucidating the "in vivo" phenomenon, the complexes of these compounds were synthetized with zinc atoms, the IR specters and quantitative chemical analyses being followed. Based on these, the possibilities of complexing the zinc from the ADH molecule by these compounds are discussed.
authors.affiliation: Institutul de medicină şi farmacie Iaşi.
authors.forename: M
authors.initials: M
authors.lastname: Proca
authors.forename: O
authors.initials: O
authors.lastname: Vicol
authors.forename: I
authors.initials: I
authors.lastname: Druţă
authors.forename: N
authors.initials: N
authors.lastname: Foca
authors.forename: M
authors.initials: M
authors.lastname: Petrovanu
authors.forename: E
authors.initials: E
authors.lastname: Stefănescu
authors.forename: M
authors.initials: M
authors.lastname: Cotrău
mesh_terms: D019342:Acetic Acid / Q000138:chemical synthesis*; D000426:Alcohol Dehydrogenase / Q000737:chemistry*; D000427:Alcohol Deterrents / Q000138:chemical synthesis*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis*; D002384:Catalysis; D047069:Pyrazolones / Q000138:chemical synthesis*; D013055:Spectrophotometry, Infrared; D015032:Zinc / Q000737:chemistry*; D019345:Zinc Acetate / Q000138:chemical synthesis*
chemical_list: D000427:Alcohol Deterrents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D047069:Pyrazolones; C038362:pyrazolone; D000426:Alcohol Dehydrogenase; D019345:Zinc Acetate; D015032:Zinc; D019342:Acetic Acid