title: Short-wavelength near infrared stimulation of the inner ear hair cells.
abstract: To explore whether the short wavelength near infrared laser can stimulate the functional hair cells, pulsed laser with wavelength of 808-nm was used to stimulate guinea pigs cochlea. Compound action potential (CAP) and auditory brainstem responses (ABR) were recorded during the experiments. We successfully recorded photomechanical responses from normal hearing animals and demonstrated the responses were not induced by optical acoustic events. Furthermore, we studied the effect of different stimulation parameters on neural response. The results show that cochlear activation can be modulated with different optical parameters.
authors.forename: Nan
authors.initials: N
authors.lastname: Xia
authors.forename: Fei
authors.initials: F
authors.lastname: Peng
authors.forename: Xing
authors.initials: X
authors.lastname: Wang
authors.forename: Xiao L
authors.initials: XL
authors.lastname: Zheng
authors.forename: Xiao P
authors.initials: XP
authors.lastname: Wan
authors.forename: Wei
authors.initials: W
authors.lastname: Yuan
authors.forename: Wen S
authors.initials: WS
authors.lastname: Hou
mesh_terms: D000161:Acoustic Stimulation; D000200:Action Potentials; D000818:Animals; D003638:Deafness / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006168:Guinea Pigs; D006199:Hair Cells, Auditory, Inner / Q000502:physiology* / Q000528:radiation effects; D007259:Infrared Rays; D007834:Lasers; D008297:Male; D010775:Photic Stimulation