title: Mycophenolate mofetil in erosive genital lichen planus: a case and review of the literature.
abstract: Erosive genital lichen planus is a disabling, inflammatory mucocutaneous condition that can cause significant patient morbidity and loss of function. Treatment initially involves topical corticosteroids but some patients can have severe treatment-resistant courses requiring systemic immunosuppression. With potentially unfavorable adverse effect profiles and subsequent intolerance of these agents by patients, erosive lichen planus can ultimately be a challenging condition to treat effectively. We present a case of a 66-year-old woman with treatment-resistant erosive genital lichen planus who was successfully managed with mycophenolate mofetil. Although there is only weak evidence for this agent in this condition, its role in dermatology is growing due to its efficacy and advantageous adverse effect profile and should therefore be considered in patients with treatment-resistant erosive genital lichen planus.
authors.affiliation: Department of Dermatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
authors.forename: Kristyn
authors.initials: K
authors.lastname: Deen
authors.forename: Erin
authors.initials: E
authors.lastname: McMeniman
mesh_terms: D000368:Aged; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008010:Lichen Planus / Q000188:drug therapy*; D009173:Mycophenolic Acid / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid
keywords: erosive genital lichen planus; lichen planus; mycophenolate mofetil