title: Thumb carpometacarpal joint congruence during functional tasks and thumb range-of-motion activities.
abstract: Joint incongruity is often cited as a possible etiological factor for the high incidence of thumb carpometacarpal (CMC) joint osteoarthritis (OA) in older women. There is evidence suggesting that biomechanics plays a role in CMC OA progression, but little is known about how CMC joint congruence, specifically, differs among different cohorts. The purpose of this in vivo study was to determine if CMC joint congruence differs with sex, age, and early stage OA for different thumb positions. Using CT data from 155 subjects and a congruence metric that is based on both articular morphology and joint posture, we did not find any differences in CMC joint congruence with sex or age group, but found that patients in the early stages of OA exhibit lower congruence than healthy subjects of the same age group.
authors.forename: Eni
authors.initials: E
authors.lastname: Halilaj
authors.forename: Douglas C
authors.initials: DC
authors.lastname: Moore
authors.forename: Tarpit K
authors.initials: TK
authors.lastname: Patel
authors.forename: David H
authors.initials: DH
authors.lastname: Laidlaw
authors.forename: Amy L
authors.initials: AL
authors.lastname: Ladd
authors.forename: Arnold-Peter C
authors.initials: AP
authors.lastname: Weiss
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Crisco
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001696:Biomechanical Phenomena; D052737:Carpometacarpal Joints / Q000503:physiopathology*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D012720:Severity of Illness Index; D012737:Sex Factors; D013933:Thumb / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed