title: Ipsilesional limb ataxia and truncal ipsipulsion in isolated infarction of the superior cerebellar peduncle.
abstract: The clinical features of a lesion confined to the superior cerebellar peduncle (SCP) have not been defined well in human. A 92-year-old woman suddenly developed mild dysarthria and severe imbalance from an isolated unilateral SCP infarction, and examination showed ipsiversive ocular torsion, severe ipsilesional limb ataxia, and truncal ipsipulsion. These findings are well consistent with those observed in monkeys when the SCP was severed. In addition to the dentate-rubro-thalamic projections, the SCP appears to contain the fibers involved in the control of eye motion in the roll plane.
authors.affiliation: Department of Neurology, Ajou University School of Medicine, Ajou University Hospital, Suwon, South Korea.
authors.forename: Sun-Uk
authors.initials: SU
authors.lastname: Lee
authors.affiliation: Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
authors.forename: Hee-Joon
authors.initials: HJ
authors.lastname: Bae
authors.affiliation: Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea. Electronic address: jisookim@snu.ac.kr.
authors.forename: Ji-Soo
authors.initials: JS
authors.lastname: Kim
mesh_terms: D000369:Aged, 80 and over; D001259:Ataxia / Q000209:etiology*; D020520:Brain Infarction / Q000150:complications / Q000473:pathology*; D002531:Cerebellum / Q000473:pathology*; D004401:Dysarthria / Q000209:etiology*; D005260:Female; D006801:Humans
keywords: Ataxia; Cerebellar infarction; Saccade; Superior cerebellar peduncle; Uncinate fasciculus; Vertigo