title: Evaluation of a multiplex bead immunoassay for determination of immune status to varicella-zoster virus in medical center students and employees.
abstract: This study evaluated an enzyme immunoassay, a multiplex bead immunoassay (MBIA), and the anticomplement immunofluorescence (ACIF) test for detecting varicella-zoster virus IgG antibodies in sera from medical center students and employees. The agreement between methods was ≥95%. The MBIA was less sensitive than was the ACIF test, with a negative predictive value of 66.7%.
authors.affiliation: Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA mjloeffe@utmb.edu.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Loeffelholz
authors.affiliation: Focus Diagnostics, San Juan Capistrano, California, USA.
authors.forename: Harry E
authors.initials: HE
authors.lastname: Prince
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D005260:Female; D005455:Fluorescent Antibody Technique; D006282:Health Personnel; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006801:Humans; D007118:Immunoassay / Q000379:methods; D007124:Immunoenzyme Techniques / Q000379:methods; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D013336:Students, Health Occupations; D013337:Students, Medical
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G