title: Epidemiology and treatment strategies of iliac vein thrombophlebitis.
abstract: BACKGROUND
  This study aimed to determine the epidemiology of iliac vein thrombophlebitis and describe gender differences associated with the management of this pathology.
  
  
  METHODS
  The 2010 National Inpatient Sample was retrospectively reviewed to include all inpatients with ICD-9 codes identifying iliac vein thrombophlebitis (451.81). Demographics, disposition, anticoagulation, thrombolytics, stent placement, open operative intervention, complications (deep vein thrombosis/pulmonary embolism), and mortality rates were reported. Statistical analysis included descriptive statistics and Student's t-testing with P < 0.05 deemed significant.
  
  
  RESULTS
  The incidence of iliac vein thrombophlebitis was 1/1,000,000 people. Men had an average age of 48 ± 20 years and women were significantly older at 59 ± 18 years (P = 0.02). There were no differences in treatment strategies or rates of complications between men and women including pulmonary embolism (23% for males, 16% of females) and deep vein thrombosis (29% for males and 19% for females). Length of stay between groups was not significant (11 ± 20 days for males and 7.7 ± 6 days for females). Overall mortality was 1.5%.
  
  
  CONCLUSIONS
  Iliac vein thrombophlebitis is a rare disease. Females who develop iliac vein thrombophlebitis are significantly older than their male counterparts. The rates of deep vein thrombosis, pulmonary embolism, and interventional strategies are not different between the sexes.
authors.affiliation: Center for Translational Injury Research (CeTIR), Department of Surgery, University of Houston-Texas, Houston, TX, USA Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA andua@mcw.edu.
authors.forename: Anahita
authors.initials: A
authors.lastname: Dua
authors.affiliation: Department of Vascular Surgery, Southern Illinois University, Springfield, IL, USA.
authors.forename: Sapan S
authors.initials: SS
authors.lastname: Desai
authors.affiliation: Private Industry, North Carolina, USA.
authors.forename: Naveen
authors.initials: N
authors.lastname: Kumar
authors.affiliation: Department of Surgery, Johns Hopkins Vein Center, Baltimore, MD, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Heller
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects; D003430:Cross-Sectional Studies; D016208:Databases, Factual; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation; D005260:Female; D054624:Health Status Disparities; D054625:Healthcare Disparities; D006801:Humans; D007084:Iliac Vein; D015994:Incidence; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D015607:Stents; D015912:Thrombolytic Therapy / Q000009:adverse effects; D013924:Thrombophlebitis / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology; D014656:Vascular Surgical Procedures / Q000009:adverse effects
chemical_list: D000925:Anticoagulants
keywords: Iliac vein thrombophlebitis; incidence of iliac vein thrombophlebitis; thrombophlebitis