title: Perianesthetic development of diaphragmatic hernia in a horse with equine pituitary pars intermedia dysfunction (PPID).
abstract: A 21-year-old Thoroughbred gelding with a history of equine pituitary pars intermedia dysfunction (PPID) presented with priapism of 2 days' duration. The horse received a caudal morphine epidural and then underwent corpus cavernosum lavage and phallectomy under general anesthesia. The patient's recovery featured multiple unsuccessful attempts to stand and his respiratory distress persisted for several hours until he acutely developed severe colic and was euthanized. Necropsy findings revealed a pituitary adenoma of the pars intermedia, bilateral adrenal cortical hyperplasia, and diaphragmatic herniation. This report suggests that horses with PPID may present a greater risk for diaphragmatic hernia under general anesthesia or during procedures placing stress on the diaphragm, including anesthetic recovery.
authors.affiliation: Department of Large Animal Medicine, College of Veterinary Medicine, 501 DW Brooks Drive, University of Georgia, Athens, Georgia 30602, USA.
authors.forename: Molly K
authors.initials: MK
authors.lastname: Shepard
authors.affiliation: Department of Large Animal Medicine, College of Veterinary Medicine, 501 DW Brooks Drive, University of Georgia, Athens, Georgia 30602, USA.
authors.forename: Wesley L
authors.initials: WL
authors.lastname: Lee
authors.affiliation: Department of Large Animal Medicine, College of Veterinary Medicine, 501 DW Brooks Drive, University of Georgia, Athens, Georgia 30602, USA.
authors.forename: Randy B
authors.initials: RB
authors.lastname: Eggleston
mesh_terms: D000818:Animals; D006548:Hernia, Diaphragmatic / Q000209:etiology / Q000662:veterinary*; D006734:Horse Diseases / Q000209:etiology* / Q000473:pathology; D006736:Horses; D008297:Male; D010900:Pituitary Diseases / Q000150:complications / Q000662:veterinary*; D052716:Pituitary Gland, Intermediate / Q000473:pathology*