title: Autologous serum eye drops for severe dry eye syndrome in a patient with chronic graft-versus-host disease: a case report.
abstract: We present the case of a 49-year-old woman with severe dry eye syndrome caused by chronic graft-versus-host disease that developed after an allogeneic hematopoietic transplant to treat acute myelogenous leukemia. After the use of commercially manufactured products for the treatment of dry eye failed to relieve her photosensitivity, blurred. vision, and severe bilateral ocular pain, she benefitted significantly from therapy with compounded autologous serum eye drops. Comments from that patient are included in this report, as are a formulation for the preparation of autologous eye drops and suggestions for their safe and effective use.
authors.affiliation: The Compounding Pharmacy, Hickory, North Carolina, USA.
authors.forename: Bill
authors.initials: B
authors.lastname: Mixon
authors.forename: Jan
authors.initials: J
authors.lastname: Mixon
authors.forename: Edward K
authors.initials: EK
authors.lastname: Isbey
authors.forename: Shari
authors.initials: S
authors.lastname: Sprinkle
mesh_terms: D002908:Chronic Disease; D015352:Dry Eye Syndromes / Q000209:etiology / Q000628:therapy*; D005260:Female; D006086:Graft vs Host Disease / Q000150:complications*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000627:therapeutic use*; D014184:Transplantation, Homologous
chemical_list: D009883:Ophthalmic Solutions