title: Bladder perforation secondary to primary systemic amyloidosis.
abstract: Amyloidosis is a disorder of protein folding characterized by extracellular aggregation and deposition of amyloid protein fibrils. Light-chain amyloidosis, also known as primary systemic amyloidosis, is the most common form of the disease. We present a case of an 84-year-old male with a history of systemic primary amyloidosis causing genitourinary, cardiac, and autonomic dysfunction who presented with hematuria and hypotension secondary to bladder perforation. He underwent open repair of a large extraperitoneal bladder defect. He ultimately died as a result of medical complications from his disease.
authors.affiliation: Department of Urology, Cedars-Sinai Medical Group, Cedars-Sinai Medical Center, 8635 West Third Street, Suite 870, Los Angeles, CA 90048, USA.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Dru
authors.affiliation: Department of Urology, Cedars-Sinai Medical Group, Cedars-Sinai Medical Center, 8635 West Third Street, Suite 870, Los Angeles, CA 90048, USA.
authors.forename: Tom S
authors.initials: TS
authors.lastname: Feng
authors.affiliation: Department of Urology, Cedars-Sinai Medical Group, Cedars-Sinai Medical Center, 8635 West Third Street, Suite 870, Los Angeles, CA 90048, USA.
authors.forename: Howard H
authors.initials: HH
authors.lastname: Kim