title: Airway pressures as surrogate estimates of intra-abdominal pressure.
abstract: Intra-abdominal pressure (IAP) measurements are essential to the diagnosis and management of patients with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS). Peak inspiratory pressure (PIP), plateau pressure (Pplat), and mean airway pressure (Paw) are used by some surgeons as surrogate estimates of IAP during abdominal closure. Thirty mechanically ventilated surgical/trauma patients with risk factors for IAH/ACS underwent simultaneous triplicate measurements of PIP, Pplat, Paw, and IAP. PIP, Pplat, and Paw were compared with IAP using both coefficient of determination and Bland and Altman analysis. The coefficient of determination for each airway pressure in predicting change in IAP was: PIP 5 per cent (P = 0.24), Pplat 17 per cent (P = 0.02), and Paw 15 per cent (P = 0.03). Bland and Altman analysis identified that marked variability exists between airway pressure and IAP measurements: PIP 19.3 ± 18.7 mmHg, Pplat 11.1 ± 13.7 mmHg, and Paw 2.0 ± 9.8 mmHg. Airway pressures do not accurately reflect IAP and cannot be substituted for IAP measurements in patients at risk for IAH/ACS.
authors.affiliation: University of Central Florida College of Medicine, Orlando, Florida, USA.
authors.forename: Avianne
authors.initials: A
authors.lastname: Bunnell
authors.forename: Michael L
authors.initials: ML
authors.lastname: Cheatham
mesh_terms: D034841:Abdominal Cavity / Q000503:physiopathology; D003161:Compartment Syndromes / Q000175:diagnosis / Q000503:physiopathology* / Q000517:prevention & control; D005260:Female; D005431:Florida; D006801:Humans; D007362:Intensive Care Units; D059325:Intra-Abdominal Hypertension / Q000175:diagnosis / Q000503:physiopathology* / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012121:Respiration, Artificial; D012129:Respiratory Function Tests; D012137:Respiratory System / Q000503:physiopathology*; D012307:Risk Factors