title: RetinaCAD, a system for the assessment of retinal vascular changes.
abstract: This paper introduces RetinaCAD, a system, for the fast, reliable and automatic measurement of the Central Retinal Arteriolar Equivalent (CRAE), the Central Retinal Venular Equivalent (CRVE), and the Arteriolar-to-Venular Ratio (AVR) values, as well as several geometrical features of the retinal vasculature. RetinaCAD identifies important landmarks in the retina, such as the blood vessels and optic disc, and performs artery/vein classification and vessel width measurement. The estimation of the CRAE, CRVE and AVR values on 480 images from 120 subjects has shown a significant correlation between right and left eyes and also between images of same eye acquired with different camera fields of view. AVR estimation in retinal images of 54 subjects showed the lowest values in people with diabetes or high blood pressure thus demonstrating the potential of the system as a CAD tool for early detection and follow-up of diabetes, hypertension or cardiovascular pathologies.
authors.forename: Behdad
authors.initials: B
authors.lastname: Dashtbozorg
authors.forename: Ana Maria
authors.initials: AM
authors.lastname: Mendonça
authors.forename: Susana
authors.initials: S
authors.lastname: Penas
authors.forename: Aurélio
authors.initials: A
authors.lastname: Campilho
mesh_terms: D001794:Blood Pressure; D003920:Diabetes Mellitus / Q000503:physiopathology; D003936:Diagnosis, Computer-Assisted; D006801:Humans; D007091:Image Processing, Computer-Assisted; D012161:Retinal Artery / Q000473:pathology* / Q000503:physiopathology; D012169:Retinal Vein / Q000473:pathology* / Q000503:physiopathology; D014584:User-Computer Interface