title: Evaluation of remineralizing potential of commercially available child formula dentifrices: an in vitro study.
abstract: OBJECTIVE
  The aim of this in vitro study is to evaluate the remineralizing potential of commercially available low fluoride child formula dentifrice on primary teeth.
  
  
  METHODS
  Total 30 primary teeth were placed in demineralizing solution for 96 hours to produce artificial carious lesions of approximately 100 μm depth, and then cut longitudinally into 30 sections of 100-150 μm thickness and randomly assigned to three groups. Sections were treated with dentifrices containing Colgate ® (anti tooth decay) 500 ppm NaF, Cheerio gel ® 458 ppm MFP and Vicco ® non-fluoridated dentifrice. Lesions were evaluated using polarized light microscopy.
  
  
  RESULTS
  Colgate ® (anti tooth decay) 500 ppm NaF sections exhibited a statistically significant decrease in lesion depth (P < 0.05, paired t-test), whereas those in Cheerio gel ® 458 ppm MFP showed a decrease in lesion depth but was not statistically significant. Vicco ® non-fluoridated dentifrice showed increase in lesion depth.
  
  
  METHODS
  A paired t-test is used to evaluate pre- and post-treatment lesion depth measurements, and Newman-Keuls multiple post hoc procedures was carried out to compare pair-wise difference of pre- and post-treatment lesion depth.
  
  
  CONCLUSIONS
  The Colgate ® (anti tooth decay) 500 ppm NaF dentifrice and Cheerio gel ® 458 ppm MFP demonstrated remineralization of carious lesions by virtue of decrease in lesion depth, whereas Vicco ® non-fluoridated dentifrice showed increase in lesion depth.
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Maratha Mandal's, Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belgaum, Karnataka, India.
authors.forename: Apurva Jagdish
authors.initials: AJ
authors.lastname: Gujarathi
authors.forename: Santosh M
authors.initials: SM
authors.lastname: Sholapurmath
authors.forename: Praveenkumar S
authors.initials: PS
authors.lastname: Mandroli
authors.forename: Deepa B
authors.initials: DB
authors.lastname: Benni
mesh_terms: D002648:Child; D003802:Dentifrices / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D014089:Tooth Remineralization; D014094:Tooth, Deciduous
chemical_list: D003802:Dentifrices