title: Bipyridine hydrogel for selective and visible detection and absorption of Cd(2+).
abstract: Herein, we report for the first time the use of bipyridine-based hydrogel for selective and visible detection and absorption of Cd(2+). At low concentrations, hydrogelator 1 was applied for selective detection of Cd(2+) in vitro and in living cells with high sensitivity. In the absence of metal ions, 1 is nonfluorescent at 470 nm. Upon addition of metal ions, 1 selectively coordinates to Cd(2+), causing an 86-fold increase of fluorescence intensity at 470 nm via the chelation enhanced fluorescence (CHEF) effect, as revealed by first-principles simulations. At 1.5 wt% and pH 5.5, 1 self-assembles into nanofibers to form hydrogel Gel I. Since Cd(2+) could actively participate in the hydrogelation and promote the self-assembly, we also successfully applied Gel I for visible detection and absorption of Cd(2+). With these excellent properties, Gel I is expected to be explored as one type of versatile biomaterial for not only environmental monitoring but also for pollution treatment in the near future.
authors.affiliation: CAS Key Laboratory of Soft Matter Chemistry, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. gliang@ustc.edu.cn.
authors.forename: Qingqing
authors.initials: Q
authors.lastname: Miao
authors.forename: Ziye
authors.initials: Z
authors.lastname: Wu
authors.forename: Zijuan
authors.initials: Z
authors.lastname: Hai
authors.forename: Changlu
authors.initials: C
authors.lastname: Tao
authors.forename: Qingpan
authors.initials: Q
authors.lastname: Yuan
authors.forename: Yadi
authors.initials: Y
authors.lastname: Gong
authors.forename: Yafeng
authors.initials: Y
authors.lastname: Guan
authors.forename: Jun
authors.initials: J
authors.lastname: Jiang
authors.forename: Gaolin
authors.initials: G
authors.lastname: Liang
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D002104:Cadmium / Q000032:analysis* / Q000737:chemistry; D045744:Cell Line, Tumor; D002614:Chelating Agents / Q000737:chemistry; D020285:Cryoelectron Microscopy; D004784:Environmental Monitoring; D005456:Fluorescent Dyes / Q000737:chemistry; D005782:Gels; D056945:Hep G2 Cells; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry*; D020100:Hydrogels / Q000737:chemistry; D007477:Ions; D057230:Limit of Detection; D008670:Metals / Q000737:chemistry; D046529:Microscopy, Electron, Transmission; D008958:Models, Molecular; D015394:Molecular Structure; D036103:Nanotechnology; D011725:Pyridines / Q000737:chemistry; D013050:Spectrometry, Fluorescence
chemical_list: D001672:Biocompatible Materials; D002614:Chelating Agents; D005456:Fluorescent Dyes; D005782:Gels; D020100:Hydrogels; D007477:Ions; D008670:Metals; D011725:Pyridines; D002104:Cadmium; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate