title: On the brink: a new synaptic vesicle release model at the calyx of held.
abstract: How vesicle calcium sensors interact with calcium channels at synapses affects neurotransmitter release dynamics. In this issue of Neuron, Nakamura et al. (2015) propose that synaptic vesicles are tightly coupled around the perimeter of a voltage-gated calcium channel cluster.
authors.affiliation: Neuroscience Research Center, NeuroCure Excellence Cluster, Charité Universitätsmedizin, Charitéplatz 1, 10117 Berlin, Germany.
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Herman
authors.affiliation: Neuroscience Research Center, NeuroCure Excellence Cluster, Charité Universitätsmedizin, Charitéplatz 1, 10117 Berlin, Germany. Electronic address: christian.rosenmund@charite.de.
authors.forename: Christian
authors.initials: C
authors.lastname: Rosenmund
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D020864:Calcium Channels, N-Type / Q000378:metabolism*; D005089:Exocytosis / Q000502:physiology*; D017729:Presynaptic Terminals / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism*; D013572:Synaptic Vesicles / Q000378:metabolism*
chemical_list: D020864:Calcium Channels, N-Type; D002118:Calcium