title: Spectrum of morphological and visual changes due to vitreomacular interface disorders encountered in a large consecutive cohort of patients.
abstract: OBJECTIVE
  Identify the incidence of vitreomacular traction (VMT) and frequency of reduced vision in the absence of other coexisting macular pathology using a pragmatic classification system for VMT in a population of patients referred to the hospital eye service.
  
  
  METHODS
  A detailed survey of consecutive optical coherence tomography (OCT) scans was done in a high-throughput ocular imaging service to ascertain cases of vitreomacular adhesion (VMA) and VMT using a departmental classification system. Analysis was done on the stages of traction, visual acuity, and association with other macular conditions.
  
  
  RESULTS
  In total, 4384 OCT scan episodes of 2223 patients were performed. Two hundred and fourteen eyes had VMA/VMT, with 112 eyes having coexisting macular pathology. Of 102 patients without coexisting pathology, 57 patients had VMT grade between 2 and 8, with a negative correlation between VMT grade and number of Snellen lines (r=-0.61717). There was a distinct cutoff in visual function when VMT grade was higher than 4 with the presence of cysts and sub retinal separation and breaks in the retinal layers.
  
  
  CONCLUSIONS
  VMT is a common encounter often associated with other coexisting macular pathology. We estimated an incidence rate of 0.01% of VMT cases with reduced vision and without coexisting macular pathology that may potentially benefit from intervention. Grading of VMT to select eyes with cyst formation as well as hole formation may be useful for targeting patients who are at higher risk of visual loss from VMT.
authors.affiliation: Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
authors.forename: W
authors.initials: W
authors.lastname: Fusi-Rubiano
authors.affiliation: Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
authors.forename: M
authors.initials: M
authors.lastname: Awad
authors.affiliation: Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
authors.forename: R
authors.initials: R
authors.lastname: Manjunath
authors.affiliation: Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
authors.forename: I
authors.initials: I
authors.lastname: Elaraoud
authors.affiliation: Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
authors.forename: N
authors.initials: N
authors.lastname: Narendran
authors.affiliation: 1] Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK [2] Faculty of Life and Health Sciences, Aston University, Birmingham, UK.
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
mesh_terms: D015331:Cohort Studies; D005128:Eye Diseases / Q000145:classification / Q000175:diagnosis*; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D012164:Retinal Diseases / Q000145:classification / Q000175:diagnosis*; D012189:Retrospective Studies; D000267:Tissue Adhesions / Q000145:classification / Q000175:diagnosis; D041623:Tomography, Optical Coherence; D014786:Vision Disorders / Q000175:diagnosis*; D014792:Visual Acuity / Q000502:physiology; D014822:Vitreous Body / Q000473:pathology*