title: Long-Term Outcomes of Proximal Gastrectomy versus Total Gastrectomy for Upper-Third Gastric Cancer.
abstract: OBJECTIVE
  There are two surgical procedures for proximal early gastric cancer (EGC): total gastrectomy (TG) and proximal gastrectomy (PG). This study aimed to compare the long-term outcomes of PG with those of TG.
  
  
  METHODS
  Between January 2001 and December 2008, 170 patients were diagnosed with proximal EGC at Soonchunhyang University Cheonan Hospital, of which 64 patients underwent PG and 106 underwent TG. Clinicopathologic features, postoperative complications, blood chemistry data, changes in body weight, and oncological outcomes were analyzed and retrospectively compared between both groups.
  
  
  RESULTS
  Tumor size was smaller and the number of retrieved lymph nodes was lower in the PG group. The postoperative complication rate was 10.9% in the TG group and 16.9% in the PG group. The incidence of Los Angeles grade C and D reflux esophagitis was significantly higher in the TG group. Hemoglobin level was higher and body weight loss was greater in the TG group at 2, 3, and 5 years postoperatively. The albumin levels at 3 and 5 years were lower in the TG group. There was no significant difference in the 5-year overall survival rates between the two groups (P=0.789).
  
  
  CONCLUSIONS
  Postoperative complications and oncologic outcomes were observed to be similar between the two groups. The PG group showed better laboratory data and weight loss than did the TG group. Moreover, severe reflux esophagitis occurred less frequently in the PG group than in the TG group. PG can be considered as an effective surgical treatment for proximal EGC.
authors.affiliation: Department of Surgery, Soonchunhyang University Hospital Cheonan, Cheonan, Korea.
authors.forename: Myoung Won
authors.initials: MW
authors.lastname: Son
authors.affiliation: Department of Surgery, Soonchunhyang University Hospital Seoul, Seoul, Korea.
authors.forename: Yong Jin
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: Department of Surgery, Soonchunhyang University Hospital Bucheon, Bucheon, Korea.
authors.forename: Gui Ae
authors.initials: GA
authors.lastname: Jeong
authors.affiliation: Department of Surgery, Soonchunhyang University Hospital Bucheon, Bucheon, Korea.
authors.forename: Gyu Seok
authors.initials: GS
authors.lastname: Cho
authors.affiliation: Department of Surgery, Soonchunhyang University Hospital Cheonan, Cheonan, Korea.
authors.forename: Moon Soo
authors.initials: MS
authors.lastname: Lee
keywords: Proximal gastrectomy; Stomach neoplasms; Total gastrectomy