title: Axonal regeneration inhibitors: emerging therapeutic options.
abstract: For the most part, the central nervous system is unable to regenerate. The majority of injuries of vascular, inflammatory, degenerative and traumatic aetiology lead to an irreversible loss of central nervous system function. The paper presents the role of Nogo-A, MAG and OMgp proteins in the inhibition of central nervous system regeneration, and their potential clinical significance.
authors.affiliation: Nicolaus Copernicus University, Toruń, Poland. trosoch@gmail.com.
authors.forename: T W
authors.initials: TW
authors.lastname: Rosochowicz
authors.affiliation: Nicolaus Copernicus University, Toruń, Poland.
authors.forename: S
authors.initials: S
authors.lastname: Wrotek
authors.affiliation: Nicolaus Copernicus University, Toruń, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Kozak
mesh_terms: D000818:Animals; D001369:Axons / Q000473:pathology / Q000502:physiology; D002493:Central Nervous System Diseases / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D009185:Myelin Proteins / Q000502:physiology*; D009416:Nerve Regeneration / Q000502:physiology*; D000070798:Nogo Proteins
chemical_list: D009185:Myelin Proteins; D000070798:Nogo Proteins; C000603199:RTN4 protein, human
keywords: MAG; Nogo-A; OMgp; Regeneration of the central nervous system