title: [Clindamycin as adjuvant therapy in Staphilococcal skin scalded syndrome].
abstract: Staphylococcal scalded skin syndrome (SSSS) is a dermatologic disease caused by exotoxins produced by Staphylococcus aureus. The disease presents as a painful cutaneous rash that culminates with the detachment of the superficial dermis. The usual treatment is antibiotics with beta-lactamase resistant penicillin. We report the case of a patient who presented with SSSS with initial torpid evolution despite antibiotic treatment and after the introduction of clindamycin IV experienced a very significant improvement. Concerns about the increase of methicillin resistant Staphylococcus aureus (MRSA) and the pathophysiology of this disease make bacteriostatic spectrum antistaphylococcal antibiotics, such as clindamycin, strong candidates for consideration as a first-line therapeutic arsenal for the treatment of SSSS.
authors.affiliation: Servicio de Pediatría, Hospital García Orcoyen, Estella, 31200, Spain. fj.gil.saenz@cfnavarra.es.
authors.forename: F J
authors.initials: FJ
authors.lastname: Gil Sáenz
authors.forename: M
authors.initials: M
authors.lastname: Herranz Aguirre
authors.forename: G
authors.initials: G
authors.lastname: Durán Urdániz
authors.forename: L
authors.initials: L
authors.lastname: Zandueta Pascual
authors.forename: J
authors.initials: J
authors.lastname: Gimeno Ballester
authors.forename: E
authors.initials: E
authors.lastname: Bernaola Iturbe
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D002675:Child, Preschool; D002981:Clindamycin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D013206:Staphylococcal Scalded Skin Syndrome / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D002981:Clindamycin