title: Host genes and their effect on the intestinal microbiome garden.
abstract: We are only beginning to understand the relationship between host genetics and the gut microbiome. Two recent studies help to disentangle this interaction and show that genetic loci across the human genome shape the gut microbiome. This opens the possibility that an unexpected number of genetic factors act directly on microbial composition and function to modulate immune pathways and metabolic phenotypes in host physiology and disease.
authors.affiliation: Division of Digestive Diseases and Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095 USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Jacobs
authors.affiliation: Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095 USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Braun