title: Alcoholic liver disease--epidemiology and risk factors.
abstract: Alcoholic liver disease (ALD) accounts for the majority of chronic liverdiseases in Occidental countries and remains a major cause of liver-related mortality in worldwide. The spectrum of ALD includes steatosis in patients which consume over 80g of alcohol per day, alcoholic steatohepatitis and liver cirrhosis in approximately 15% of patients. Once cirrhosis is established, the annual risk for hepatocellular carcinoma is about 1-2%. Environmental factors such as drinking patterns, coexisting liver disease, obesity, diet and co-medication may affect the natural course of ALD. Abstinence is the hallmark of therapy for ALD, and nutritional therapy is the first line in therapeutical intervention.
authors.affiliation: University of Medicine and Pharmacy Grigore T. Popa - Iaşi, Department of Medical Specialties.
authors.forename: Camelia-eliza
authors.initials: CE
authors.lastname: Cojocariu
authors.forename: Anca-Victoriţa
authors.initials: AV
authors.lastname: Trifan
authors.forename: Irina
authors.initials: I
authors.lastname: Gîrleanu
authors.forename: C
authors.initials: C
authors.lastname: Stanciu
mesh_terms: D015992:Body Mass Index; D006528:Carcinoma, Hepatocellular / Q000453:epidemiology / Q000209:etiology; D000431:Ethanol / Q000009:adverse effects*; D014943:Global Health / Q000706:statistics & numerical data; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000453:epidemiology / Q000209:etiology; D008108:Liver Diseases, Alcoholic / Q000150:complications* / Q000453:epidemiology* / Q000209:etiology; D008113:Liver Neoplasms / Q000453:epidemiology / Q000209:etiology; D009765:Obesity / Q000453:epidemiology / Q000209:etiology; D015995:Prevalence; D011379:Prognosis; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D015996:Survival Rate; D013997:Time Factors
chemical_list: D000431:Ethanol