title: Roles of 3,3',4',5-tetrachlorosalicylanilide in regulating extracellular electron transfer of Shewanella oneidensis MR-1.
abstract: Microbial extracellular electron transfer (EET) is critically involved in many pollutant conversion processes in both natural environment and engineered bioelectrochemical systems (BES), but typically with limited efficiency and poor controllability. In this study, we discover an important role of uncouplers in affecting the microbial energy metabolism and EET. Dose of lower-concentration 3,3',4',5-tetrachlorosalicylanilide (TCS) in the anolyte promoted the current generation and substrate degradation of an MFC inoculated with Shewanella oneidensis MR-1. However, higher TCS dosage caused obvious microbial inhibition. Our results suggest a previously unknown role of uncouplers in regulating the microbial EET. In addition, the underlying mechanisms of such processes are investigated. This work broadens our view about the EET behaviors of microorganisms in real water environment where uncouplers are usually present, and suggests a possible new approach to regulate microbial EET in BES.
authors.affiliation: 1] Department of Chemistry, University of Science &Technology of China, Hefei, 230026, China [2] China Academy of Engineering Physics, P. O. Box 919, Mianyang 621900, China.
authors.forename: Yong-Peng
authors.initials: YP
authors.lastname: Wang
authors.affiliation: Department of Chemistry, University of Science &Technology of China, Hefei, 230026, China.
authors.forename: Sheng-Song
authors.initials: SS
authors.lastname: Yu
authors.affiliation: 1] Department of Chemistry, University of Science &Technology of China, Hefei, 230026, China [2] China Academy of Engineering Physics, P. O. Box 919, Mianyang 621900, China.
authors.forename: Hai-Ling
authors.initials: HL
authors.lastname: Zhang
authors.affiliation: 1] Department of Chemistry, University of Science &Technology of China, Hefei, 230026, China [2] Collaborative Innovation Center of Suzhou Nano Science and Technology, University of Science &Technology of China, Hefei, 230026, China.
authors.forename: Wen-Wei
authors.initials: WW
authors.lastname: Li
authors.affiliation: Department of Chemistry, University of Science &Technology of China, Hefei, 230026, China.
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Cheng
authors.affiliation: Department of Chemistry, University of Science &Technology of China, Hefei, 230026, China.
authors.forename: Han-Qing
authors.initials: HQ
authors.lastname: Yu
mesh_terms: D004579:Electron Transport / Q000187:drug effects*; D005110:Extracellular Space / Q000378:metabolism; D019344:Lactic Acid / Q000378:metabolism; D006180:Proton-Translocating ATPases / Q000037:antagonists & inhibitors; D012458:Salicylanilides / Q000494:pharmacology*; D020592:Shewanella / Q000187:drug effects* / Q000378:metabolism*
chemical_list: D012458:Salicylanilides; D019344:Lactic Acid; D006180:Proton-Translocating ATPases; C003390:3,3',4',5-tetrachlorosalicylanilide