title: Clinical evaluation of the efficacy of one self-adhesive composite in dental hypersensitivity.
abstract: OBJECTIVE
  The aim of the present study was to investigate the clinical effectiveness over 12 weeks of Vertise Flow(™), a self-adhering composite, in dental hypersensitivity (DH).
  
  
  METHODS
  The study was conducted as a split-mouth randomized clinical trial. Vertise Flow™ was compared to the following: (1) Universal Dentine Sealant, (2) Clearfil Protect Bond, and (3) Flor-Opal® Varnish. A total of 46 patients with 116 hypersensitive teeth were studied. Pain experience was generated by a cold stimulus and assessed using the visual analog scale (VAS) of pain. The response was recorded before the application of the materials (pre-1), immediately after (post-1), at 1- (post-2), 2- (post-3), and 12-week controls (post-4). Statistical differences in VAS were performed using the Kruskal-Wallis analysis at the different time-points (P < 0.05), adjusting statistical significances for multiple comparisons (Bonferroni correction).
  
  
  RESULTS
  All the materials showed any statistically significant differences at the baseline. After the application of each material, a VAS decrease was demonstrated at every post-control. VF showed significant hypersensitivity reduction in post-1. Statistically significant relief was also observed in post-2 while no significant differences were detected in post-3 and post-4.
  
  
  CONCLUSIONS
  After 12-week controls, there was no statistically significant hypersensitivity reduction using VF in respect to the other materials. On the other hand, any significant differences were detected in the decrease of the VAS irrespective of the desensitizing agent employed at the 12-week controls.
  
  
  CONCLUSIONS
  The significant increase in VAS scores within the 12-weeks of environment suggested there is instability of VF when used as desensitizing agent.
authors.affiliation: Department of Biomedical Sciences, University of Sassari, Viale San Pietro, 43/c, 07100, Sassari, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Pinna
authors.forename: A
authors.initials: A
authors.lastname: Bortone
authors.forename: G
authors.initials: G
authors.lastname: Sotgiu
authors.forename: S
authors.initials: S
authors.lastname: Dore
authors.forename: P
authors.initials: P
authors.lastname: Usai
authors.forename: E
authors.initials: E
authors.lastname: Milia
mesh_terms: D003738:Dental Cements / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D016896:Treatment Outcome
chemical_list: D003738:Dental Cements