title: Comparison of percentage body fat and body mass index for the prediction of inflammatory and atherogenic lipid risk profiles in elderly women.
abstract: OBJECTIVE
  To compare the clinical classification of the body mass index (BMI) and percentage body fat (PBF) for the prediction of inflammatory and atherogenic lipid profile risk in older women.
  
  
  METHODS
  Cross-sectional analytical study with 277 elderly women from a local community in the Federal District, Brazil. PBF and fat-free mass (FFM) were determined by dual energy X-ray absorptiometry. The investigated inflammatory parameters were interleukin 6 and C-reactive protein.
  
  
  RESULTS
  Twenty-five percent of the elderly women were classified as normal weight, 50% overweight, and 25% obese by the BMI. The obese group had higher levels of triglycerides and very low-density lipoproteins than did the normal weight group (P≤0.05) and lower levels of high-density lipoproteins (HDL) than did the overweight group (P≤0.05). According to the PBF, 49% of the elderly women were classified as eutrophic, 28% overweight, and 23% obese. In the binomial logistic regression analyses including age, FFM, and lipid profile, only FFM (odds ratio [OR]=0.809, 95% confidence interval [CI]: 0.739-0.886; P<0.0005) proved to be a predictor of reaching the eutrophic state by the BMI. When the cutoff points of PBF were used for the classification, FFM (OR=0.903, CI=0.884-0.965; P=0.003) and the total cholesterol/HDL ratio (OR=0.113, CI=0.023-0.546; P=0.007) proved to be predictors of reaching the eutrophic state.
  
  
  CONCLUSIONS
  Accurate identification of obesity, systemic inflammation, and atherogenic lipid profile is key to assessing the risk of cardiometabolic diseases. Classification based on dual energy X-ray absorptiometry measures, along with biochemical and inflammatory parameters, seems to have a great clinical importance, since it allows the lipid profile eutrophic distinction in elderly overweight women.
authors.affiliation: University of Brasília (UnB), Brasília, DF, Brazil.
authors.forename: Silvana Schwerz
authors.initials: SS
authors.lastname: Funghetto
authors.affiliation: Center University of Brasilia (UNICEUB), Brasilia, DF, Brazil.
authors.forename: Alessandro de Oliveira
authors.initials: Ade O
authors.lastname: Silva
authors.affiliation: Laboratory of Exercise Physiology, Faculty Estácio de Sá of Vitória, ES, Brazil.
authors.forename: Nuno Manuel Frade
authors.initials: NM
authors.lastname: de Sousa
authors.affiliation: University of Brasília (UnB), Brasília, DF, Brazil.
authors.forename: Marina Morato
authors.initials: MM
authors.lastname: Stival
authors.affiliation: Catholic University of Brasília, Brasília, DF, Brazil.
authors.forename: Ramires Alsamir
authors.initials: RA
authors.lastname: Tibana
authors.affiliation: University of Brasília (UnB), Brasília, DF, Brazil.
authors.forename: Leonardo Costa
authors.initials: LC
authors.lastname: Pereira
authors.affiliation: University of Brasília (UnB), Brasília, DF, Brazil.
authors.forename: Marja Letícia Chaves
authors.initials: ML
authors.lastname: Antunes
authors.affiliation: University of Brasília (UnB), Brasília, DF, Brazil.
authors.forename: Luciano Ramos
authors.initials: LR
authors.lastname: de Lima
authors.affiliation: Catholic University of Brasília, Brasília, DF, Brazil.
authors.forename: Jonato
authors.initials: J
authors.lastname: Prestes
authors.affiliation: University of Brasília (UnB), Brasília, DF, Brazil.
authors.forename: Ricardo Jacó
authors.initials: RJ
authors.lastname: Oliveira
authors.affiliation: Center University of Brasilia (UNICEUB), Brasilia, DF, Brazil.
authors.forename: Maurílio Tiradentes
authors.initials: MT
authors.lastname: Dutra
authors.affiliation: University of Brasília (UnB), Brasília, DF, Brazil ; Catholic University of Brasília, Brasília, DF, Brazil.
authors.forename: Vinícius Carolino
authors.initials: VC
authors.lastname: Souza
authors.affiliation: Catholic University of Brasília, Brasília, DF, Brazil.
authors.forename: Dahan da Cunha
authors.initials: Dda C
authors.lastname: Nascimento
authors.affiliation: University of Brasília (UnB), Brasília, DF, Brazil.
authors.forename: Margô Gomes de Oliveira
authors.initials: MG
authors.lastname: Karnikowski
mesh_terms: D015502:Absorptiometry, Photon; D050154:Adiposity; D000367:Age Factors; D000368:Aged; D050197:Atherosclerosis / Q000503:physiopathology*; D015415:Biomarkers; D015992:Body Mass Index; D001835:Body Weight; D001938:Brazil; D002097:C-Reactive Protein / Q000032:analysis; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D018836:Inflammation Mediators / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood; D008055:Lipids / Q000097:blood*; D050177:Overweight
chemical_list: D015415:Biomarkers; D018836:Inflammation Mediators; D015850:Interleukin-6; D008055:Lipids; D002097:C-Reactive Protein
keywords: aging; body fat; body mass index; health profile; lipids; women