title: Estimating the cognitive effects of prevalent diabetes, recent onset diabetes, and the duration of diabetes among older adults.
abstract: BACKGROUND
  Little evidence is available on the effects of incident diabetes or diabetes duration on cognitive aging.
  
  
  METHODS
  We evaluated the effects of prevalent and incident diabetes on deteriorations in cognitive function, based on participants (n = 8,671) aged 65+ in the Health and Retirement Study in 2000. Inverse probability weighting was used to account for selective attrition and time-varying confounding of incident diabetes.
  
  
  RESULTS
  Prevalent diabetes predicted higher odds of dementia [odds ratio 1.27; 95% confidence interval (CI) 1.03-1.58] and worse memory (-0.06 in z-score units; 95% CI -0.10 to -0.02), but incident diabetes or diabetes duration up to 8 years of follow-up was not predictive.
  
  
  CONCLUSIONS
  Prevalent diabetes predicted lower cognition but not recent onset diabetes.
authors.affiliation: Institute of Social Science Survey, Peking University, Beijing, China.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Wu
authors.forename: Eric J
authors.initials: EJ
authors.lastname: Tchetgen Tchetgen
authors.forename: Theresa
authors.initials: T
authors.lastname: Osypuk
authors.forename: Jennifer
authors.initials: J
authors.lastname: Weuve
authors.forename: Kellee
authors.initials: K
authors.lastname: White
authors.forename: Mahasin
authors.initials: M
authors.lastname: Mujahid
authors.forename: M Maria
authors.initials: MM
authors.lastname: Glymour
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000523:psychology; D003071:Cognition; D003072:Cognition Disorders / Q000209:etiology* / Q000523:psychology; D015331:Cohort Studies; D003704:Dementia / Q000209:etiology; D003920:Diabetes Mellitus / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D015233:Models, Statistical; D009483:Neuropsychological Tests; D057566:Self Report; D013997:Time Factors