title: [High-risk pregnancy in a woman with Marfan syndrome, a bicuspid aortic valve, and a dilated aortic sinus].
abstract: A 29-year-old woman with Marfan syndrome, a bicuspid aortic valve, and a dilated aortic sinus (5.2 cm) presented herself in clinic 14 weeks pregnant. She was advised to discontinue the pregnancy due to risk of dissection; however, she decided to continue. She was treated with labetalol (300 mg/day) to reduce blood pressure and was admitted for bed rest from week 30. Her aortic diameter was assessed by echocardiography every 2nd week and remained unchanged. She was treated with betamethason at week 26 and the child was born by a caesarean section in week 35. The post-operative course was uneventful.
authors.forename: Kristian Ambjørn
authors.initials: KA
authors.lastname: Groth
authors.forename: Jacob Raben
authors.initials: JR
authors.lastname: Greisen
authors.forename: Birgitte Bruun
authors.initials: BB
authors.lastname: Nielsen
authors.affiliation: Hjertemedicinsk Afdeling B, Aarhus Universitetshospital, Brendstrupgaardsvej 100, 8200 Aarhus N. holmark@ki.au.dk.
authors.forename: Niels Holmark
authors.initials: NH
authors.lastname: Andersen
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001021:Aortic Valve / Q000002:abnormalities* / Q000000981:diagnostic imaging; D000082882:Bicuspid Aortic Valve Disease; D002585:Cesarean Section; D004108:Dilatation, Pathologic / Q000517:prevention & control; D004452:Echocardiography; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008382:Marfan Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000517:prevention & control*; D018566:Pregnancy, High-Risk; D012850:Sinus of Valsalva / Q000000981:diagnostic imaging
chemical_list: D000959:Antihypertensive Agents