title: Perspectives of novel imaging techniques for staging, therapy response assessment, and monitoring of surveillance in lung cancer: summary of the Dresden 2013 Post WCLC-IASLC State-of-the-Art Imaging Workshop.
abstract: Modern imaging techniques that can provide functional information on tumor vascularization, metabolic activity, or cellularity have seen significant improvements over the past decade. However, most of these techniques are currently not broadly utilized neither in clinical trials nor in clinical routine, although there is a large agreement on the fact that conventional approaches for therapy response assessment such as Response Evaluation Criteria in Solid Tumors or World Health Organization criteria-that exclusively focus on the change in tumor size-are of less value for response assessment in modern thoracic oncology. The aim of this article comprises two parts: a short review of the most promising state-of-the-art imaging techniques that have the potential to play a larger role in thoracic oncology within the near future followed by a meeting report including recommendations of an interdisciplinary expert panel that discussed the potential of the different techniques during the Dresden 2013 Post World Congress of Lung Cancer (WCLC)--International Association for the Study of Lung Cancer (IASLC) meeting. It is intended to provide a comprehensive summary about ongoing trends and future perspectives on functional imaging in thoracic oncology.
authors.affiliation: *Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; †Division of Thoracic Surgery, Royal Brompton Hospital, Imperial College London, London, United Kingdom; ‡Department of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; §Department of Medicine I, Medical University of Vienna, Vienna, Austria; ║Division of Thoracic Surgery, University Hospital of Zurich, Zurich, Switzerland; ¶Medical Oncology Division, Department of Oncology, University Hospital Perugia, Perugia, Italy; #Lung Cancer Research, University of Leicester & Leicester University Hospitals, Leicester, United Kingdom; **Department of Radiology, General Hospital Celle, Celle, Germany; ††Department of Thoracic and Vascular Surgery, Hôpital Tenon, University of Paris VI, Paris, France; ‡‡Department of Surgery/Thoracic Oncology, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; §§Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; ║║Department of Radiation Oncology, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; ¶¶Department of Pneumology, Respiratory Oncology Unit and Trial Unit, University Hospital KU Leuven, Leuven, Belgium; ##Clinical Competence Center Oncology, Siemens AG, Erlangen, Germany; ***Institute of Clinical Radiology and Nuclear Medicine/Department of Molecular Imaging & Radiopharmacy, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; †††Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263.
authors.forename: Thomas
authors.initials: T
authors.lastname: Henzler
authors.forename: Peter
authors.initials: P
authors.lastname: Goldstraw
authors.forename: Frederik
authors.initials: F
authors.lastname: Wenz
authors.forename: Robert
authors.initials: R
authors.lastname: Pirker
authors.forename: Walter
authors.initials: W
authors.lastname: Weder
authors.forename: Paul
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authors.lastname: Apfaltrer
authors.forename: Mathias
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authors.lastname: Meyer
authors.forename: Karen
authors.initials: K
authors.lastname: Buesing
authors.forename: Lucio
authors.initials: L
authors.lastname: Crino
authors.forename: Dean
authors.initials: D
authors.lastname: Fennell
authors.forename: Christian
authors.initials: C
authors.lastname: Fink
authors.forename: Dominique
authors.initials: D
authors.lastname: Grunenwald
authors.forename: Christian
authors.initials: C
authors.lastname: Manegold
authors.forename: Lothar
authors.initials: L
authors.lastname: Pilz
authors.forename: Stefan O
authors.initials: SO
authors.lastname: Schoenberg
authors.forename: Senan
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authors.lastname: Suresh
authors.forename: Johan
authors.initials: J
authors.lastname: Vansteenkiste
authors.forename: Wieland
authors.initials: W
authors.lastname: Voigt
authors.forename: Björn
authors.initials: B
authors.lastname: Wängler
authors.forename: Gerald
authors.initials: G
authors.lastname: Schmid-Bindert
mesh_terms: D003952:Diagnostic Imaging; D006801:Humans; D007157:Immunologic Surveillance; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology; D009367:Neoplasm Staging; D011859:Radiography