title: Estimation of salivary β-glucuronidase activity as a marker of periodontal disease: A case control study.
abstract: OBJECTIVE
  The aim of the present study was to estimate the salivary β-glucuronidase level in healthy and diseased periodontium and to correlate the level with clinical measurement.
  
  
  METHODS
  70 patients were included in this study with the age ranging from 30 to 65 years. Both males and females were included. They were divided into two groups: Control having healthy periodontium (n = 20) and experimental having diseased periodontium (n = 50). The parameters recorded were probing pocket depth, probing attachment level, gingival index, β-glucuronidase activity in the saliva, number of white blood cells, neutrophils, lymphocytes count, and platelet count.
  
  
  RESULTS
  It was observed that there was an increase in the level of salivary β-glucuronidase in the experimental subjects than in the control patients, and a significant positive linear relationship existed between salivary β-glucuronidase level and probing pocket depth in the experimental group.
  
  
  CONCLUSIONS
  Level of salivary β-glucuronidase increases during inflammation in the periodontium.
authors.affiliation: Department of Periodontology, Best Dental Science College, Madurai, India.
authors.forename: Chandra Sekhara
authors.initials: CS
authors.lastname: Prabhahar
authors.affiliation: Department of Oral and Maxillofacial Surgery, CSI College of Dental Sciences and Research, Madurai, India.
authors.forename: K Thanvir Mohamed
authors.initials: KT
authors.lastname: Niazi
authors.affiliation: Department of Conservative Dentistry and Endodontics, CSI College of Dental Sciences and Research, Madurai, India.
authors.forename: R
authors.initials: R
authors.lastname: Prakash
authors.affiliation: Department of Oral and Maxillofacial Surgery, Sri Venkateswara Dental College and Hospital, Chennai, Tamil Nadu, India.
authors.forename: A
authors.initials: A
authors.lastname: Yuvaraj
authors.affiliation: Department of Oral and Maxillofacial Pathology, Chandra Dental College, Barabanki, Uttar Pradesh, India.
authors.forename: Somasekhar
authors.initials: S
authors.lastname: Goud
authors.affiliation: Department of Conservative Dentistry, CKS Theja Dental College, Thirupati, Andhra Pradesh, India.
authors.forename: P
authors.initials: P
authors.lastname: Ravishekar
keywords: inflammation; periodontium; saliva; β-glucuronidase