title: The Mediating Role of Resilience on Quality of Life and Cancer Symptom Distress in Adolescent Patients With Cancer.
abstract: Understanding how cancer symptom distress and resilience contribute to quality of life (QoL) in adolescent cancer and may potentially help these patients achieve better health-related outcomes. The objective of this study was to describe cancer symptom distress, QoL, and resilience in adolescents with cancer and to determine whether resilience is a mediating variable. Forty adolescent cancer patients were recruited, and data were collected via a demographic questionnaire, the Cancer Symptom Distress Scale, the Resilience Scale, and the Minneapolis-Manchester Quality of Life Scale. Pearson's correlation, multiple regressions, and the Sobel test were conducted. Both resilience and cancer symptom distress were regressed against QoL, accounting for 62.1% of observed variation in QoL scores. The bootstrap result estimated the true indirect effect between -.0189 and -.0024, with a 95% confidence interval. Resilience mediates the relationship between cancer symptom distress and QoL. Clinical use of a resilience measure, for example to use in developing and evaluating interventions focused on enhancing resilience, may be practical for nurses.
authors.affiliation: National Taipei University of Nursing and Health Sciences, Taipei, Taiwan weiwen@ntunhs.edu.tw.
authors.forename: Wei-Wen
authors.initials: WW
authors.lastname: Wu
authors.affiliation: National Taiwan University, Taipei, Taiwan.
authors.forename: Shao-Yu
authors.initials: SY
authors.lastname: Tsai
authors.affiliation: National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
authors.forename: Shu-Yuan
authors.initials: SY
authors.lastname: Liang
authors.affiliation: National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
authors.forename: Chieh-Yu
authors.initials: CY
authors.lastname: Liu
authors.affiliation: National Taiwan University, Taipei, Taiwan.
authors.forename: Shiann-Tarng
authors.initials: ST
authors.lastname: Jou
authors.affiliation: Harvard Medical School, Boston, MA, USA.
authors.forename: Donna L
authors.initials: DL
authors.lastname: Berry
mesh_terms: D000293:Adolescent; D016497:Adolescent Health Services; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000451:nursing* / Q000523:psychology; D009859:Oncology Nursing; D010371:Pediatric Nursing; D011788:Quality of Life; D055500:Resilience, Psychological; D013315:Stress, Psychological; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: adolescent; cancer symptom; mediating effect; quality of life; resilience