title: Regioselective palladium-catalyzed decarboxylative cross-coupling reaction of alkenyl acids with coumarins: synthesis of 3-styrylcoumarin compounds.
abstract: A novel and efficient protocol for the regioselective synthesis of 3-styrylcoumarins from readily available cinnamic acids and coumarins is presented. The reaction proceeds via a decarboxylative cross-coupling mediated by a catalytic amount of Pd(OAc)2, with Ag2CO3 as an oxidant, and with 1,10-phenanthroline as a ligand. A plausible reaction mechanism for this process is depicted, and the resulting 3-styrylcoumarins show excellent fluorescence quantum yields.
authors.affiliation: Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Chemistry & Pharmaceutical Sciences of Guangxi Normal University , Guilin 541004, People's Republic of China.
authors.forename: Xu
authors.initials: X
authors.lastname: Wang
authors.forename: Shen-Yan
authors.initials: SY
authors.lastname: Li
authors.forename: Ying-Ming
authors.initials: YM
authors.lastname: Pan
authors.forename: Heng-Shan
authors.initials: HS
authors.lastname: Wang
authors.forename: Zhen-Feng
authors.initials: ZF
authors.lastname: Chen
authors.forename: Ke-Bin
authors.initials: KB
authors.lastname: Huang