title: Radiation-induced osteosarcoma might mimic metastatic bone lesions: a case with bone scan and FDG PET/CT imaging.
abstract: We report on a 53-year-old woman with osteosarcoma of the skull who underwent radiation therapy for metastatic brain tumor. She had a history of uterine endometrial cancer treated with chemotherapy and surgery 9 years previously. FDG PET/CT for surveillance showed nodular accumulation at the right suprainguinal region and very avid accumulation at the left side of the occipital bone. Bone scan showed increased accumulation at the same portion of the occipital bone. The occipital tumor was surgically removed and diagnosed as radiation-induced osteosarcoma.
authors.affiliation: From the Departments of *Nuclear Medicine, †Gynecological Oncology, and ‡Comprehensive Medical Oncology, The Cancer Institute Hospital of JFCR, Tokyo, Japan.
authors.forename: Masamichi
authors.initials: M
authors.lastname: Koyama
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Koizumi
authors.forename: Kenji
authors.initials: K
authors.lastname: Umayahara
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Takeshima
authors.forename: Shunji
authors.initials: S
authors.lastname: Takahashi
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D003951:Diagnostic Errors; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008875:Middle Aged; D064847:Multimodal Imaging; D009362:Neoplasm Metastasis; D009381:Neoplasms, Radiation-Induced / Q000000981:diagnostic imaging* / Q000473:pathology; D012516:Osteosarcoma / Q000000981:diagnostic imaging* / Q000473:pathology; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18