title: Attitude of patients with HIV infection towards organ transplant between HIV patients. A cross-sectional questionnaire survey.
abstract: This study examined the HIV patients' attitudes towards the practice of organ transplant between HIV patients using a cross-sectional survey design. In total, 206 patients participated with a mean age of 42 (±8.8) years. The majority (70%) were black African and women (54%), and 83% described themselves as heterosexual. Most participants (n = 171, 83%) were on treatment, and 159 (93%) had viral load less than 40 copies/ml. Mean duration of illness and mean duration of treatment were 77 (±42.7) and 68 (±41) months, respectively. Of all participants, 128 (62%) reported that they would consider donating either any organ or a specific organ/s to an HIV patient, 33 (16%) would not consider it and 45 (22%) were unsure about donating their organs. Furthermore, 113 (55%) participants would consider receiving an organ from an HIV patient, 37 (18%) would not consider it, and 56 (27%) were unsure. Ninety-eight participants (42%) reported that they would consider both donating and receiving an organ. Multinomial logistic regression analysis found that significantly more Black African than Caucasian participants were unsure about organ donation (p = 0.011, OR = 3.887). Participants with longer duration of infection were significantly less likely to consider receiving an organ from an HIV patient (p = 0.036, OR = 1.297). Overall, the study findings indicated that the majority of participants were in favour of organ transplant between HIV patients. Use of HIV-infected donors could potentially reduce current organ waiting list among HIV patients.
authors.affiliation: GU/HIV Medicine, Coventry and Warwickshire Partnership Trust, Coventry, UK.
authors.forename: Huda
authors.initials: H
authors.lastname: Taha
authors.affiliation: Applied Research Centre in Health and Lifestyle Interventions, Coventry University, Coventry, UK.
authors.forename: Katie
authors.initials: K
authors.lastname: Newby
authors.affiliation: School of Medicine, Birmingham University, Birmingham, UK.
authors.forename: Archik
authors.initials: A
authors.lastname: Das
authors.affiliation: GU/HIV Medicine, Coventry and Warwickshire Partnership Trust, Coventry, UK Satyajit.das@covwarkpt.nhs.uk.
authors.forename: Satyajit
authors.initials: S
authors.lastname: Das
mesh_terms: D000328:Adult; D001290:Attitude; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000523:psychology*; D006801:Humans; D019520:Living Donors / Q000523:psychology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D014019:Tissue Donors; D014850:Waiting Lists
keywords: AIDS; HIV; HIV patients; Organ transplant; antiretroviral therapy; attitude