title: Gold nanoparticles for photoacoustic imaging.
abstract: Photoacoustic (PA) imaging is a biomedical imaging modality that provides functional information regarding the cellular and molecular signatures of tissue by using endogenous and exogenous contrast agents. There has been tremendous effort devoted to the development of PA imaging agents, and gold nanoparticles as exogenous contrast agents have great potential for PA imaging due to their inherent and geometrically induced optical properties. The gold-based nanoparticles that are most commonly employed for PA imaging include spheres, rods, shells, prisms, cages, stars and vesicles. This article provides an overview of the current state of research in utilizing these gold nanomaterials for PA imaging of cancer, atherosclerotic plaques, brain function and image-guided therapy.
authors.affiliation: State Key Lab of Metal Matrix Composites, School of Materials Science & Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China.
authors.forename: Wanwan
authors.initials: W
authors.lastname: Li
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Chen
mesh_terms: D003952:Diagnostic Imaging / Q000379:methods*; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*
chemical_list: D006046:Gold
keywords: atherosclerosis; brain function; cancer; gold nanoparticle; photoacoustic imaging; therapy guidance