title: [Uterine transplantation: is there a real demand?].
abstract: OBJECTIVE
  To study the demand there is for uterus transplantation (UTx).
  
  
  METHODS
  Recent media coverage of developments in UTx prompted associations of patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and of women suffering from UI to contact us. We sent them anonymous questionnaires devised to sound out their attitude towards UTx and towards adoption and gestational surrogacy (GS). A clinical psychologist also carried out a qualitative discourse analysis.
  
  
  RESULTS
  Sixty patients answered the questionnaire. Thirty-eight patients were married or living with a male partner. Seven patients had had a hysterectomy. Fifty-one patients had uterine agenesis. Of the 60 patients, 19 and 21, respectively, had ruled out the option of adoption or GS, and 11 would not envisage either possibility. Thirty-five patients were willing to take part in a clinical study into UTx despite the uncertainty of the outcome and the potential risks involved. Of these 35 volunteers, 23 were in a heterosexual relationship and aged ≤35 years.
  
  
  CONCLUSIONS
  For women with UI the condition is all the more distressing because there is no medical solution for it. UTx could hold out hope for some of these patients despite the complexity of the procedure and the attendant risks. Because of the feelings of vulnerability engendered by UI, any UTx programme should provide full information to patients and ensure they are carefully screened and selected.
authors.affiliation: Service de gynécologie-obstétrique, hôpital Mère-Enfant, CHU de Limoges, avenue Larrey, 87000 Limoges, France; Pharmacologie, toxicologie et pharmacovigilance, Inserm, UMR-S850, CHU de Limoges, 87000 Limoges, France. Electronic address: tristan.gauthier@chu-limoges.fr.
authors.forename: T
authors.initials: T
authors.lastname: Gauthier
authors.affiliation: Centre de recherches psychanalyse, médecine et sociétés (CRPMS EA 3522), université Paris Diderot, 75013 Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Garnault
authors.affiliation: Consultations de psychiatrie, CHU de Limoges, 87000 Limoges, France.
authors.forename: J-F
authors.initials: JF
authors.lastname: Therme
authors.affiliation: Service de gynécologie-obstétrique, hôpital Mère-Enfant, CHU de Limoges, avenue Larrey, 87000 Limoges, France.
authors.forename: P
authors.initials: P
authors.lastname: Piver
authors.affiliation: Coordination hospitalière des prélèvements, CHU de Limoges, 87000 Limoges, France.
authors.forename: M
authors.initials: M
authors.lastname: Essig
authors.affiliation: Service néphrologie, dialyse et transplantation, CHU de Limoges, 87000 Limoges, France.
authors.forename: N
authors.initials: N
authors.lastname: Pichon
authors.affiliation: Pharmacologie, toxicologie et pharmacovigilance, Inserm, UMR-S850, CHU de Limoges, 87000 Limoges, France.
authors.forename: P
authors.initials: P
authors.lastname: Marquet
authors.affiliation: Service de gynécologie-obstétrique, hôpital Mère-Enfant, CHU de Limoges, avenue Larrey, 87000 Limoges, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Aubard
mesh_terms: D058489:46, XX Disorders of Sex Development / Q000150:complications; D000293:Adolescent; D000328:Adult; D001294:Attitude to Health; D000013:Congenital Abnormalities; D005260:Female; D006301:Health Services Needs and Demand; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000601:surgery; D009095:Mullerian Ducts / Q000002:abnormalities; D011795:Surveys and Questionnaires; D014599:Uterus / Q000002:abnormalities / Q000637:transplantation*; D055815:Young Adult
keywords: Adoption; Gestation pour autrui; Gestational surrogacy; Infertilité utérine; MRKH; Transplantation utérine; Uterine infertility; Uterus transplantation