title: A readily available colorimetric and near-infrared fluorescent turn-on probe for rapid and selective detection of cysteine in living cells.
abstract: A readily available naphthofluorescein-based near-infrared (NIR) fluorescent probe was reported for rapid, colorimetric and NIR fluorescent turn-on detection of cysteine (Cys) with high selectivity and sensitivity over various analytes including the similar structured homocysteine (Hcy) and glutathione (GSH). This probe was successfully applied to bioimage intracellular Cys in living cells with low cytotoxicity.
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China.
authors.forename: Shuanghong
authors.initials: S
authors.lastname: Xue
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China.
authors.forename: Shuangshuang
authors.initials: S
authors.lastname: Ding
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China.
authors.forename: Qisong
authors.initials: Q
authors.lastname: Zhai
authors.affiliation: School of Chemical and Environmental Engineering, Wuhan Polytechnic University, 68 Xuefu South Road, Wuhan 430023, PR China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan 430079, PR China. Electronic address: gf256@mail.ccnu.edu.cn.
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Feng
mesh_terms: D015374:Biosensing Techniques; D002470:Cell Survival; D003124:Colorimetry; D003545:Cysteine / Q000032:analysis*; D005452:Fluoresceins / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D061848:Optical Imaging
chemical_list: D005452:Fluoresceins; D005456:Fluorescent Dyes; C000601316:naphthofluorescein; D003545:Cysteine
keywords: Bioimage; Colorimetric; Cysteine; NIR fluorescent probe; Naphthofluorescein