title: Persistent high level of urinary tumor marker carbohydrate antigen 19-9 in prenatally diagnosed dysplastic kidney.
abstract: Tumor marker carbohydrate antigen 19-9 (CA 19-9) level has gained clinical significance in gastrointestinal malignancies and in various solid and cystic diseases. Dysplastic kidney is a congenital abnormality resulting from atresia of the ureteral bud during the embryogenesis which can be unilateral or bilateral. We report unilateral dysplastic kidney with extremely large cyst diagnosed by routine ultrasonography in the 32nd week of gestational age with high levels of CA 19-9 in cystic and amniotic fluid, as well as persistent high urinary levels of this tumor marker during the 1-year follow-up. Persistent high urinary CA 19-9 level even after cyst aspiration may be attributable to remained function of dysplastic kidney due to remained epithelial lining.
authors.affiliation: Pediatric Urology Research Center, Children's Hospital Medical Center, Pediatric Center of Excellence, Tehran University of Medical Science, No. 62, Dr. Gharib's Street, Keshavarz Boulevard, Tehran 1419733151, Iran.
authors.forename: Reza
authors.identifier: 0000-0003-2143-6068
authors.initials: R
authors.lastname: Khorramirouz
authors.affiliation: Pediatric Urology Research Center, Children's Hospital Medical Center, Pediatric Center of Excellence, Tehran University of Medical Science, No. 62, Dr. Gharib's Street, Keshavarz Boulevard, Tehran 1419733151, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Ebadi
authors.affiliation: Department of Obstetrics and Gynecology, Mirza Koochackkhan Women's Sciences Hospital, Tehran University of Medical Science, Tehran 1419433151, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Rahimi Sherbaf
authors.affiliation: Pediatric Urology Research Center, Children's Hospital Medical Center, Pediatric Center of Excellence, Tehran University of Medical Science, No. 62, Dr. Gharib's Street, Keshavarz Boulevard, Tehran 1419733151, Iran.
authors.forename: Abdol-Mohammad
authors.initials: AM
authors.lastname: Kajbafzadeh