title: Characterization of anomalous movements of spherical living cells on a silicon dioxide glassy substrate.
abstract: The random walk of spherical living cells on a silicon dioxide glassy substrate was studied experimentally and numerically. This random walk trajectory exhibited erratic dancing, which seemingly obeyed anomalous diffusion (i.e., Lévy-like walk) rather than normal diffusion. Moreover, the angular distribution (-π to π) of the cells' trajectory followed a "U-shaped pattern" in comparison to the uniform distribution seen in the movements of negatively charged polystyrene microspheres. These effects could be attributable to the homeostasis-driven structural resilient character of cells and physical interactions derived from temporarily retained nonspecific binding due to weak forces between the cells and substrates. Our results provide new insights into the stochastic behavior of mesoscopic biological particles with respect to structural properties and physical interactions.
authors.affiliation: Department of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.
authors.forename: Myeonggu
authors.initials: M
authors.lastname: Son
authors.affiliation: Department of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.
authors.forename: Gyudo
authors.initials: G
authors.lastname: Lee
authors.affiliation: Department of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.
authors.forename: Jongsang
authors.initials: J
authors.lastname: Son
authors.affiliation: Department of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.
authors.forename: Seungyeop
authors.initials: S
authors.lastname: Choi
authors.affiliation: Department of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.
authors.forename: Youngho
authors.initials: Y
authors.lastname: Kim
authors.affiliation: Department of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.
authors.forename: Sei-Young
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Department of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.
authors.forename: Young-Ro
authors.initials: YR
authors.lastname: Yoon
authors.affiliation: School of Biomedical Engineering, Korea University , Seoul 136-703, South Korea.
authors.forename: Dae Sung
authors.initials: DS
authors.lastname: Yoon
authors.affiliation: Department of Biomedical Engineering, Yonsei University , Wonju 220-710, South Korea.
authors.forename: Sang Woo
authors.initials: SW
authors.lastname: Lee