title: Evaluation of path-history-based fluorescence Monte Carlo method for photon migration in heterogeneous media.
abstract: The path-history-based fluorescence Monte Carlo method used for fluorescence tomography imaging reconstruction has attracted increasing attention. In this paper, we first validate the standard fluorescence Monte Carlo (sfMC) method by experimenting with a cylindrical phantom. Then, we describe a path-history-based decoupled fluorescence Monte Carlo (dfMC) method, analyze different perturbation fluorescence Monte Carlo (pfMC) methods, and compare the calculation accuracy and computational efficiency of the dfMC and pfMC methods using the sfMC method as a reference. The results show that the dfMC method is more accurate and efficient than the pfMC method in heterogeneous medium.
authors.forename: Xu
authors.initials: X
authors.lastname: Jiang
authors.forename: Yong
authors.initials: Y
authors.lastname: Deng
authors.forename: Zhaoyang
authors.initials: Z
authors.lastname: Luo
authors.forename: Kan
authors.initials: K
authors.lastname: Wang
authors.forename: Lichao
authors.initials: L
authors.lastname: Lian
authors.forename: Xiaoquan
authors.initials: X
authors.lastname: Yang
authors.forename: Igor
authors.initials: I
authors.lastname: Meglinski
authors.forename: Qingming
authors.initials: Q
authors.lastname: Luo
mesh_terms: D000818:Animals; D003198:Computer Simulation; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008856:Microscopy, Fluorescence / Q000379:methods*; D008954:Models, Biological; D015233:Models, Statistical; D009010:Monte Carlo Method; D009391:Nephelometry and Turbidimetry / Q000379:methods*; D017785:Photons; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity