title: Effects of a community-based multimodal exercise program on physical function and quality of life in cancer survivors: a pilot study.
abstract: The purpose of this single-arm pilot study was to examine the effects of a community-based multimodal exercise program on: physical function (Timed-Up-and-Go [TUG], 6-min walk test [6MWT], leg and chest press strength, and functional reach [FR]); and quality of life, QoL [FACT-G]), in cancer survivors. Fifty-nine cancer survivors (91.5% female; mean age 59 ± 12 years) completed supervised exercise training for 90 min twice weekly for 12 weeks. Exercise training consisted of 30 min of each of the following: (1) aerobic conditioning; (2) resistance training; and (3) balance and flexibility training. Pre-post-outcome measures were compared for statistically significant differences (p < 0.01) and were related to the International Classification of Functioning, Disability and Health Model. Effect sizes (ES), minimal clinically important differences, and minimal detectable change at 90% confidence intervals were calculated. Participants decreased TUG time by 21.1% and walked 15.5% farther during 6-MWT (p < 0.001). Leg and chest press strength increased by 34.5% and 32.7%, respectively (p < 0.001). FR increased by 15.1% (p < 0.001). Significant improvements for physical well-being (13.9%), emotional well-being (6.7%), functional well-being (13.0%), and total well-being (9.6%) were found (p < 0.01). Improvements in physical function and QoL showed "moderate to large" ESs indicating improvements in physical function and QoL are clinically meaningful.
authors.affiliation: Department of Physical Therapy, Georgia Regents University , Augusta, GA , USA .
authors.forename: Michael P
authors.initials: MP
authors.lastname: Foley
authors.forename: Vernon A
authors.initials: VA
authors.lastname: Barnes
authors.forename: Scott M
authors.initials: SM
authors.lastname: Hasson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001696:Biomechanical Phenomena; D003153:Community Health Services; D004185:Disability Evaluation; D004644:Emotions; D005080:Exercise Test; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D005845:Georgia; D006304:Health Status; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D053580:Muscle Strength; D009369:Neoplasms / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D064797:Physical Conditioning, Human; D010865:Pilot Projects; D004856:Postural Balance; D011788:Quality of Life; D020127:Recovery of Function; D055070:Resistance Training; D011795:Surveys and Questionnaires; D017741:Survivors / Q000523:psychology*; D013997:Time Factors; D016896:Treatment Outcome
keywords: Cancer survivors; exercise; physical activity; physical function; quality of life