title: The T-SPOT.TB Test for Diagnosis of Breast Tuberculosis.
abstract: OBJECTIVE
  To assess the diagnostic value of the T-SPOT.TB test in cases of breast turberculosis (BTB) in China.
  
  
  METHODS
  We enrolled 13 female patients with primary BTB as the BTB test group and 10 healthy volunteers as the control group. The 2 groups underwent T-SPOT.TB tests and tuberculin skin tests (TSTs) before receiving a core-needle biopsy or excision biopsy. We then collected and analyzed T-SPOT.TB and TST data.
  
  
  RESULTS
  The sensitivity of the T-SPOT.TB test for detection of BTB (84.6%) was significantly greater than that of TST (53.8%) (P <.05); the specificity of each test (80.0% and 60.0%, respectively) for BTB was not significantly different (P >.05).
  
  
  CONCLUSIONS
  The T-SPOT.TB test could be a useful adjunct to current tests for diagnosis of BTB and could be used for early diagnosis of this condition.
authors.affiliation: Departments of Breast Surgery and.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhong
authors.affiliation: Departments of Breast Surgery and.
authors.forename: Xing-Lu
authors.initials: XL
authors.lastname: Zhou
authors.affiliation: Pathology, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.affiliation: Pathology, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
authors.forename: Yan-Mei
authors.initials: YM
authors.lastname: Zhang
authors.affiliation: Pathology, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
authors.forename: Yu-Fei
authors.initials: YF
authors.lastname: Jiao
authors.affiliation: Departments of Breast Surgery and.
authors.forename: Bao-Liang
authors.initials: BL
authors.lastname: Guo
authors.affiliation: Departments of Breast Surgery and.
authors.forename: Zhao-Qi
authors.initials: ZQ
authors.lastname: Yan
authors.affiliation: Departments of Breast Surgery and harbinmu03@163.com.
authors.forename: Jian-Guo
authors.initials: JG
authors.lastname: Zhang
mesh_terms: D000328:Adult; D001940:Breast / Q000382:microbiology* / Q000473:pathology*; D002681:China; D015622:Epithelioid Cells / Q000473:pathology; D005260:Female; D015744:Giant Cells, Langhans / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D012867:Skin / Q000382:microbiology / Q000473:pathology*; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis*; D055815:Young Adult
keywords: BTB; T-SPOT.TB; TST; breast tuberculosis; diagnosis; sensitivity