title: [Club drug use and its association with syphilis infection among female sex workers].
abstract: OBJECTIVE
  To understand the prevalence rates of club drug use and how it associated with syphilis infection among female sex workers (FSWs) in different areas of China so as to provide reference for developing intervention programs.
  
  
  METHODS
  In each of the study site, different kinds of venues where FSWs solicited clients were mapped and grouped into three strata. The number of FSWs at each venue was enumerated. A stratified proportional sampling design was adopted to recruit FSWs. Questionnaire survey was conducted to gather data on demographic information, club drug use and sexual behaviors. Blood samples were taken and tested for syphilis. Factors associated with syphilis infection and club drug use were assessed using univariate and multivariate logistic regression models.
  
  
  RESULTS
  Results of the 1 630 participants, 120 (7.4%)used club drugs in the past 12 months, and 5.4% (88/1 630)tested positive for syphilis. Syphilis positive rate was not significantly different between FSWs who used club drugs and those who did not. Data from multivariate logistic regression analysis indicated that club drug use was associated with following factors as sites of the study, hometown of the FSWs, marital status, education level, having had STD symptoms or history of injecting drugs in the past 12 months of the sex workers.
  
  
  CONCLUSIONS
  Club drug use was highly prevalent among FSWs. Further studies are warranted to fully explore the association between club drug use and the risk of HIV/STD transmission.
authors.affiliation: Chinese Academy of Medical Sciences Institute of Dermatology/National Center for STD Control, Chinese Center for Disease Control and Prevention, Nanjing 210042, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.affiliation: Chinese Academy of Medical Sciences Institute of Dermatology/National Center for STD Control, Chinese Center for Disease Control and Prevention, Nanjing 210042, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Jiang
authors.affiliation: Chinese Academy of Medical Sciences Institute of Dermatology/National Center for STD Control, Chinese Center for Disease Control and Prevention, Nanjing 210042, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Yue
authors.affiliation: Chinese Academy of Medical Sciences Institute of Dermatology/National Center for STD Control, Chinese Center for Disease Control and Prevention, Nanjing 210042, China. Email: gxdchina@163.com.
authors.forename: Xiangdong
authors.initials: X
authors.lastname: Gong
mesh_terms: D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D013287:Illicit Drugs; D015995:Prevalence; D060386:Sex Workers / Q000523:psychology* / Q000706:statistics & numerical data; D012725:Sexual Behavior; D019966:Substance-Related Disorders / Q000453:epidemiology*; D013587:Syphilis / Q000453:epidemiology*
chemical_list: D013287:Illicit Drugs