title: [The 10-year stroke risk in hypertensive outpatients combined with diabetes in cardiovascular clinics of 36 tertiary hospitals in China].
abstract: OBJECTIVE
  To assess the estimated 10-year risk of stroke among hypertensive outpatients known with diabetes from cardiovascular clinics of 36 tertiary hospitals in China and to analyze the characteristics of the risk factors and the 10-year risk of stroke between the southern and the northern patients.
  
  
  METHODS
  A multi-center prevalence survey was conducted from October 2011 to June 2012. Hypertensive outpatients known with diabetes were enrolled from cardiovascular clinics of 36 tertiary hospitals in China. A total of 15 914 outpatients were included in the final analysis. The 10-year probability of stroke was evaluated by the Framingham stroke risk profile. According to the 10-year probability of stroke, patients were divided into low risk ( ≤ 5%), medium risk (6%∼9%) and high risk ( ≥ 10%).
  
  
  RESULTS
  (1) Of all the hypertensive outpatients known with diabetes, the mean age was (64.6 ± 10.1) years and the mean systolic pressure was (138.7 ± 19.3) mmHg (1 mmHg = 0.133 kPa). Among them, 7.4% with atrial fibrillation, 11.2% with left ventricular hypertrophy, 57.2% with cardiovascular diseases, 17.1% smokers and 37.0% using mono-hypoglycemic agent. The southern patients who were older with more smokers had higher proportions of men and left ventricular hypertrophy, lower levels of systolic blood pressure, and lower proportions of other cardiovascular diseases than those of the northern patients ( all P < 0.05). (2) The mean 10-year probability of stroke was (20.9 ± 16.2) %. The southern patients had a higher mean 10-year probability of stroke than that of the northern patients [(22.4 ± 17.1) % vs (19.7 ± 15.2) %] (P < 0.01) . After adjusted by age and sex, the southern patients still had a higher mean 10-year probability of stroke (P < 0.05) . (3) All the patients had 7.7% with low risk, 17.4% with medium risk, and 74.9% with high risk. The southern patients had lower proportions of low and medium risk than those of the northern patients (6.7% vs 8.4%, 15.5% vs 18.9%), but had a higher proportion of high risk than that of the northern patients (77.7% vs 72.7%, all P < 0.01).
  
  
  CONCLUSIONS
  Among the hypertensive outpatients known with diabetes from the cardiovascular clinics of our study, most of them were at the 10-year high risk of stroke. The southern patients had a higher mean 10-year probability of stroke than that of the northern patients.
authors.forename: Bingnan
authors.initials: B
authors.lastname: Bao
authors.forename: Yingsheng
authors.initials: Y
authors.lastname: Zhou
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing 100034, China. Email: huoyong @263.net.cn.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huo
mesh_terms: D000368:Aged; D000554:Ambulatory Care Facilities / Q000706:statistics & numerical data*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D044466:Asian People; D001281:Atrial Fibrillation; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000208:ethnology; D002681:China / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000188:drug therapy / Q000208:ethnology; D005260:Female; D006761:Hospitals / Q000706:statistics & numerical data*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy / Q000208:ethnology*; D017379:Hypertrophy, Left Ventricular; D007004:Hypoglycemic Agents / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D010045:Outpatients; D015995:Prevalence; D011336:Probability; D012111:Residence Characteristics; D012307:Risk Factors; D020521:Stroke / Q000208:ethnology* / Q000209:etiology; D062606:Tertiary Care Centers
chemical_list: D000959:Antihypertensive Agents; D007004:Hypoglycemic Agents