title: The Relationship between the Localization, Size, Stage and Histopathology of the Primary Laryngeal Tumor with Neck Metastasis.
abstract: OBJECTIVE
  In this study we aimed the investigate the laryngectomy (partial and total) and neck dissection (functional, radical) in patients undergoing larynx identified as a result of the operation of primary tumour localization, size, stage and histopathology of the relationship between neck metastasis.
  
  
  METHODS
  The files of 118 patients who has had operation of laryngectomy (partly, total) and neck dissection (functional, radical) because of larynx cancer in the Ear Nose and Throat (ENT) Clinic in the last ten years (1997-2007) have been evaluated retrospectively.
  
  
  RESULTS
  116 of them were male and 2 of them were female. Age average was 56+/-22. 189 neck dissections have been applied to 118 patients. While in supraglottic tumours, 55.2% cervical metastasis and 28.9% occult metastasis have been determined, in transglottic tumours 35.1% cervical metastasis and 18.9% occult metastasis have been determined. It has been seen that while the cervical metastasis ratio of tumours bigger than 4 cm is 55.8%, the tumours smaller than 4 cm is 27.27% (p=0.002). The cervical metastasis rate has been determined as 26.3% in T1 cases, 25.8% in T2 cases, 40.6% in T3 cases and 58.3% in T4 cases. In tumours with advanced T stage, the rate of cervical metastasis has been seen more than the ones with early T stage (p=0.027). Cervical metastasis has been determined as 27.3% in good differential (G1) tumours, 53.4% in medium differential (G2) tumours, and 74.1% in bad differential (G3) tumours (p=0.005).
  
  
  CONCLUSIONS
  Considered in the light of clinical parameters specified in the cervical lymph node metastasis, N0 patients with laryngeal cancer, tumour, according to the anatomical location as unilateral or bilateral elective neck dissection should be performed and histopathological specimens taken in the event of a positive detection of metastases concluded that postoperative radiotherapy should be performed.
authors.affiliation: Department of Otolaryngology, Erzurum Education and Research Hospital, Erzurum, Turkey.
authors.forename: Vahit
authors.initials: V
authors.lastname: Mutlu
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: Harun
authors.initials: H
authors.lastname: Ucuncu
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: Enver
authors.initials: E
authors.lastname: Altas
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Aktan
keywords: Larynx cancer; T stage; cervical lymph node metastasis; histopathological grade; localization; size