title: Hybrid resection of a giant thigh plexiform neurofibroma.
abstract: METHODS
  Authors present a case of a 55 year old patient with Type 1 neurofibromatosis (NF1) and a very large right thigh plexiform neurofibroma. The patient had increasing difficulty with mobilization due to this enlarging bulky mass. Preoperative embolization reduced the bleeding risk at surgery allowing successful gross resection of the mass by a multidisciplinary surgical team. Limb function was restored to normal.
  
  
  CONCLUSIONS
  Massive plexiform neurofibromatosis is a rare expression of von Recklinghausen's disease or NF1. These large masses result in severe disfigurement and significant functional disability. They are extremely vascular and there is potential for malignant transformation.
  
  
  CONCLUSIONS
  These massive tumors require complex preoperative, intraoperative and postoperative management strategies with involvement from a multidisplinary team. We discuss the challenges of surgical intervention and to discuss the current literature.
authors.affiliation: Department of Musculoskeletal Oncology Mount Sinai Hospital, Department of Vascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital, Toronto, ON, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Kolker
authors.affiliation: Department of Musculoskeletal Oncology Mount Sinai Hospital, Department of Vascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital, Toronto, ON, Canada.
authors.forename: J S
authors.initials: JS
authors.lastname: Wunder
authors.affiliation: Department of Musculoskeletal Oncology Mount Sinai Hospital, Department of Vascular Surgery, Peter Munk Cardiac Centre, Toronto General Hospital, Toronto, ON, Canada. Electronic address: graham.roche-nagle@uhn.on.ca.
authors.forename: G
authors.initials: G
authors.lastname: Roche-Nagle
keywords: Multidisplinary team; Neurofibromatosis; Plexiform neurofibroma