title: Perineural spread of malignant melanoma from the mandible to the brachial plexus: case report.
abstract: Perineural spread is a well-known mechanism of dissemination of head and neck malignancies. There are few reports of melanoma involving the brachial plexus in the literature. To their knowledge, the authors report the first known case of perineural spread of malignant melanoma to the brachial plexus. Clinicoradiological and anatomopathological correlation is presented, highlighting the importance of peripheral nerve communications in perineural spread.
authors.affiliation: Departments of 1 Neurosurgery.
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Restrepo
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Spinner
authors.forename: B Matthew
authors.initials: BM
authors.lastname: Howe
authors.forename: Mark E
authors.initials: ME
authors.lastname: Jentoft
authors.forename: Svetomir N
authors.initials: SN
authors.lastname: Markovic
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Lachance
mesh_terms: D001917:Brachial Plexus / Q000473:pathology* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008339:Mandibular Neoplasms / Q000473:pathology*; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009460:Neurologic Examination; D019635:Neurosurgical Procedures / Q000379:methods; D010524:Peripheral Nervous System Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D016896:Treatment Outcome
keywords: brachial plexus; cervical plexus; malignant melanoma; oncology; perineural spread; peripheral nerve