title: [A case of long-term survival after peritoneal recurrence of rectal cancer achieved by tumorectomy and adjuvant chemotherapy].
abstract: The patient was a 40-year-old woman.She began experiencing abdominal pain and constipation in July 2005.S he underwent endoscopy in August, which revealed rectal cancer.She was referred to our hospital for surgery and underwent anterior resection with lymph node dissection in September. The pathological diagnosis was tub2, SS, N2, ly1, v1, stage III b. After discharge, she began oral chemotherapy. However, in April 2006, computed tomography (CT) revealed recurrence in the Douglas pouch. She began FOLFOX4 treatment in May.On follow-up CT performed in July, the recurrent sites were limited to 2 nodules and were deemed resectable. The patient underwent peritoneal dissemination resection, and the pathological diagnosis was metastatic tumor.She subsequently received 11 postoperative FOLFOX4 courses. The chemotherapy regimen was changed to the de Gramont regimen because of peripheral neuropathy. After 56 courses of the de Gramont regimen, the chemotherapy regimen was further changed to UFT/UZEL. The patient received 28 additional courses but experienced hair loss and requested treatment cessation. To date, she remains alive without recurrence.
authors.affiliation: Dept. of Thoracic and Visceral Organ Surgery, Gunma University Graduate School of Medicine.
authors.forename: Kengo
authors.initials: K
authors.lastname: Takahashi
authors.forename: Takamichi
authors.initials: T
authors.lastname: Igarashi
authors.forename: Kazumi
authors.initials: K
authors.lastname: Tanaka
authors.forename: Norifumi
authors.initials: N
authors.lastname: Takahashi
authors.forename: Keitaro
authors.initials: K
authors.lastname: Hirai
authors.forename: Hotaka
authors.initials: H
authors.lastname: Yamazaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsukagoshi
authors.forename: Hiroomi
authors.initials: H
authors.lastname: Ogawa
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yoshinari
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Sunose
authors.forename: Izumi
authors.initials: I
authors.lastname: Takeyoshi
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D012008:Recurrence; D013997:Time Factors