title: Alternative screening for dense breasts: MRI.
abstract: OBJECTIVE. The purpose of this article is to review the use of MRI in breast density measurement and breast cancer risk estimation and to discuss the role of MRI as an alternative screening to mammography for screening women with dense breasts. CONCLUSION. The potential of MRI for screening women with dense breasts remains controversial because of the paucity of clinical evidence, the possibility of overdiagnosis, and the cost-effectiveness of the technique in this population. Although methods of MRI measurement require standardization and automation, future addition of MRI density to risk models may positively impact their value.
authors.affiliation: 1 All authors: Institute of Cancer Research and Royal Marsden National Health Service Foundation Trust, Downs Rd, Sutton, Surrey SM2 5PT, United Kingdom.
authors.forename: Elizabeth A M
authors.initials: EA
authors.lastname: O'Flynn
authors.forename: Araminta E W
authors.initials: AE
authors.lastname: Ledger
authors.forename: Nandita M
authors.initials: NM
authors.lastname: deSouza
mesh_terms: D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis*; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging
keywords: MRI; breast cancer screening; breast density