title: Stroke after coronary artery bypass surgery with and without cardiopulmonary bypass.
abstract: BACKGROUND
  Stroke is a devastating complication of coronary artery bypass grafting (CABG). This study was carried out with the aim that the development of off pump coronary artery surgery decreases the incidence/adverse outcome due to extra corporeal circulation.
  
  
  METHODS
  The data utilized in this study was extracted from a randomized controlled trial that was conducted from January 2006 to March 2007 at Punjab Institute of Cardiology. One hundred patients were included in 'on pump' group-A, and 100 patients in 'off pump' group-B.
  
  
  RESULTS
  The mean age of the patients in group-A was 53.51 ± 9.96 years and in group-B it was 51.59 ± 10.30 years. Renal failure occurred in 21% patients of group-A as compared to 10% of group-B while Acute Myocardial Infarction occurred in significantly higher number of patients in group-B (11%) as compared to group-A (2%). Off pump was associated with significant decrease in rate of stroke 1.5% as compared to on pump 3.5%. similarly there was decreased in the risk of deaths after stroke 0% as compared to on pump 1.5% mortality after stroke. In group A 6 (3.5%) patients developed stroke where as in group-B 2 (1.5%) patients developed stroke out of these 6 patients there were 2 mortalities after stroke in group-A while in group-B there was no mortality after stroke within 30 days postoperatively.
  
  
  CONCLUSIONS
  Off pump CABG is associated with significantly decreased rate of stroke in comparison with the on-pump CABG.
authors.affiliation: Punjab Institute of Cardiology, Lahore, Pakistan. aw_3989@yahoo.com
authors.forename: Javed
authors.initials: J
authors.lastname: Iqbal
authors.forename: Abdul
authors.initials: A
authors.lastname: Ghaffar
authors.forename: Ahmad
authors.initials: A
authors.lastname: Shahbaz
authors.forename: Abdul Rehman
authors.initials: AR
authors.lastname: Abid
mesh_terms: D000328:Adult; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D047549:Coronary Artery Bypass, Off-Pump / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology; D011379:Prognosis; D051437:Renal Insufficiency / Q000453:epidemiology; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology*