title: Screening of antimicrobial activity of macroalgae extracts from the Moroccan Atlantic coast.
abstract: The aim of this work is the screening of the antimicrobial activity of seaweed extracts against pathogenic bacteria and yeasts. The antimicrobial activity of the dichloromethane and ethanol extracts of ten marine macroalgae collected from the Moroccan's Atlantic coast (El-Jadida) was tested against two Gram+ (Bacillus subtilis and Staphylococcus aureus) and two Gram- (Escherichia coli and Pseudomonas aeruginosa) human pathogenic bacteria, and against two pathogenic yeasts (Candida albicans and Cryptococcus neoformans) using the agar disk-diffusion method. Seven algae (70%) of ten seaweeds are active against at least one pathogenic microorganisms studied. Five (50%) are active against the two studied yeast with an inhibition diameter greater than 15 mm for Cystoseira brachycarpa. Six (60%) seaweeds are active against at least one studied bacteria with five (50%) algae exhibiting antibacterial inhibition diameter greater than 15 mm. Cystoseira brachycarpa, Cystoseira compressa, Fucus vesiculosus, and Gelidium sesquipedale have a better antimicrobial activity with a broad spectrum antimicrobial and are a potential source of antimicrobial compounds and can be subject of isolation of the natural antimicrobials.
authors.affiliation: Laboratoire contrôle qualité en bio-industrie et molécules bio-actives, faculté des sciences, université Chouaib Doukkali, BP 20, 24000 El-Jadida, Morocco.
authors.forename: M
authors.initials: M
authors.lastname: El Wahidi
authors.affiliation: Laboratoire contrôle qualité en bio-industrie et molécules bio-actives, faculté des sciences, université Chouaib Doukkali, BP 20, 24000 El-Jadida, Morocco; Faculté polydisciplinaire de Taroudant, université Ibn Zohr, BP 271, 83000 Taroudant, Morocco. Electronic address: elamraouibelkassem@yahoo.fr.
authors.forename: B
authors.initials: B
authors.lastname: El Amraoui
authors.affiliation: Laboratoire contrôle qualité en bio-industrie et molécules bio-actives, faculté des sciences, université Chouaib Doukkali, BP 20, 24000 El-Jadida, Morocco.
authors.forename: M
authors.initials: M
authors.lastname: El Amraoui
authors.affiliation: Laboratoire contrôle qualité en bio-industrie et molécules bio-actives, faculté des sciences, université Chouaib Doukkali, BP 20, 24000 El-Jadida, Morocco.
authors.forename: T
authors.initials: T
authors.lastname: Bamhaoud
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D005658:Fungi / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D058086:Microalgae / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009018:Morocco; D012624:Seaweed / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents
keywords: Activité antibactérienne; Activité antifongique; Antibacterial activity; Antifungal activity; Candida; Cryptococcus; Macroalgae; Macroalgues