title: Is the ICH score a valid predictor of mortality in intracerebral hemorrhage?
abstract: OBJECTIVE
  The intracerebral hemorrhage (ICH) score utilizes a 0- to 6-point scoring system to predict 30-day mortality in ICH patients. The purpose of this analysis was to (a) validate the ICH score in an international, heterogeneous population of ICH patients; and (b) assess the usefulness of a 72-h ICH score.
  
  
  METHODS
  Analyses were based on data from 399 patients in the Novo Nordisk trial F7ICH-1371. The ICH score's ability to predict mortality was determined by calculating the sensitivity, specificity, and positive predictive value (PPV).
  
  
  CONCLUSIONS
  Both the baseline and 72-h ICH score had high specificity but low sensitivity resulting in an overall PPV of 57%-76%. Specificity of the ICH score was higher in the baseline ICH score (95%) as compared to the 72-h score (89%). Sensitivity of the ICH score was higher in the 72-h ICH score (75%) as compared to the baseline score (36%).
  
  
  CONCLUSIONS
  The baseline ICH score provides reasonable PPV while the 72-h score provides higher sensitivity. ICH scores obtained at baseline and/or 72 h are valid and may help practitioners to more accurately predict 30-day mortality in ICH patients.
authors.affiliation: Department of Neurosciences, University of California San Diego, La Jolla, California.
authors.forename: Dawn M
authors.initials: DM
authors.lastname: Meyer
authors.affiliation: Novo Nordisk A/S, Bagsvaerd, Denmark.
authors.forename: Kamilla
authors.initials: K
authors.lastname: Begtrup
authors.affiliation: University of Texas Health Science Center at Houston, Houston, Texas.
authors.forename: James C
authors.initials: JC
authors.lastname: Grotta
mesh_terms: D002543:Cerebral Hemorrhage / Q000401:mortality* / Q000451:nursing / Q000503:physiopathology; D003718:Denmark; D015600:Glasgow Coma Scale; D006801:Humans; D011237:Predictive Value of Tests; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
keywords: Vascular disease; critical care; neurology; patient outcomes