title: Predicting long-term outcomes of acute aortic dissection: a focus on gender.
abstract: Acute aortic disease ranks as the 19th leading cause of death with steadily increasing incidence. The prevalence of aneurysms varies depending on the localization along the aorta with a mortality of aortic rupture of around 80%. Traditionally, aortic disease affects men more frequently than women, however, with a varying gender ratio. Nevertheless, in the setting of acute aortic dissection, the International Registry of Acute Aortic Dissections identified significant gender-related differences in the management of both sexes with acute aortic conditions. Current data suggest that women are at an increased risk of both dying from aortic dissection and having aorta-related complications than men. This review aims to report on current evidence of gender impact on natural history, treatment and outcomes in patients with acute aortic dissection.
authors.affiliation: Department of Cardiology, Heart Center, University Hospital Rostock, D-18057 Rostock, Germany.
authors.forename: Dimitar
authors.initials: D
authors.lastname: Divchev
authors.forename: Tarek
authors.initials: T
authors.lastname: Najjar
authors.forename: Falko
authors.initials: F
authors.lastname: Tillwich
authors.forename: Tim
authors.initials: T
authors.lastname: Rehders
authors.forename: Holger
authors.initials: H
authors.lastname: Palisch
authors.forename: Christoph A
authors.initials: CA
authors.lastname: Nienaber
mesh_terms: D000208:Acute Disease; D000784:Aortic Dissection / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D000818:Animals; D001014:Aortic Aneurysm / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D005260:Female; D054625:Healthcare Disparities / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D008297:Male; D017063:Outcome Assessment, Health Care; D015995:Prevalence; D012737:Sex Factors; D013997:Time Factors
keywords: TAA; aortic dissection; gender; outcome; thoracic endovascular stent-graft repair