title: Forging a potent vaccine adjuvant: CpG ODN/cationic peptide nanorings.
abstract: Type I interferon inducers may potentially be engineered to function as antiviral and anticancer agents, or alternatively, vaccine adjuvants, all of which may have clinical applications. We recently described a simple strategy to convert a Toll-like receptor 9 (TLR9) agonist devoid of interferon α (IFNα) stimulating activity into a robust Type I interferon inducer with potent vaccine adjuvant activity.
authors.affiliation: Department of Biological Sciences; Middle East Technical University ; Ankara, Turkey.
authors.forename: Bilgi
authors.initials: B
authors.lastname: Gungor
authors.affiliation: Department of Molecular Biology and Genetics Bilkent University ; Ankara, Turkey.
authors.forename: Fuat Cem
authors.initials: FC
authors.lastname: Yagci
authors.affiliation: Department of Molecular Biology and Genetics Bilkent University ; Ankara, Turkey.
authors.forename: Ihsan
authors.initials: I
authors.lastname: Gursel
authors.affiliation: Department of Biological Sciences; Middle East Technical University ; Ankara, Turkey.
authors.forename: Mayda
authors.initials: M
authors.lastname: Gursel
keywords: CpG ODN; Type I interferon; vaccine adjuvant