title: Second-look ultrasonography for MRI-detected suspicious breast lesions in patients with breast cancer.
abstract: OBJECTIVE
  The purpose of this study is to evaluate the use of second-look ultrasonography (US) for investigating additional suspicious lesions detected on preoperative staging magnetic resonance imaging (MRI) for breast cancer.
  
  
  METHODS
  Between September 2008 and August 2010, 1,970 breast MRIs were performed at our medical institution for the evaluation of breast cancer before surgery. Second-look US was recommended for 135 patients with 149 suspicious lesions, following the MRI interpretation, and 108 patients with 121 lesions were included in this study. The detection rate on second-look US, according to the lesion type, diameter, and histopathological outcome, was analyzed.
  
  
  RESULTS
  Of the 121 lesions considered in this study, 97 (80.2%) were diagnosed on MRI as masses and 24 (19.8%) as non-mass-like lesions; 105 lesions (86.8%) were correlated and 16 (13.2%) were not correlated with the findings of second-look US. Of the 105 correlated lesions, 29 (27.6%) were proven to be malignant and 76 (72.4%) were benign. Although a greater number of large malignant lesions were correlated on second-look US than small benign lesions, there was no statistically significant difference according to lesion diameter or type, as seen on MRI or pathology.
  
  
  CONCLUSIONS
  We have concluded that second-look US is a useful diagnostic tool for lesions incidentally detected on breast MRI, as in this study, it could identify 86.8% of the MRI-detected breast lesions.
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Min Ji
authors.identifier: 0000-0001-7818-4346
authors.initials: MJ
authors.lastname: Hong
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Joo Hee
authors.identifier: 0000-0002-1446-8195
authors.initials: JH
authors.lastname: Cha
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Hak Hee
authors.identifier: 0000-0002-2956-9212
authors.initials: HH
authors.lastname: Kim
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Hee Jung
authors.identifier: 0000-0002-3398-1074
authors.initials: HJ
authors.lastname: Shin
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Eun Young
authors.identifier: 0000-0002-3478-6721
authors.initials: EY
authors.lastname: Chae
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea ; Department of Radiology, Gangnam CHA Hospital, CHA University College of Medicine, Seoul, Korea.
authors.forename: Ji Eun
authors.identifier: 0000-0003-1173-8142
authors.initials: JE
authors.lastname: Shin
authors.affiliation: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Woo Jung
authors.identifier: 0000-0003-1341-6470
authors.initials: WJ
authors.lastname: Choi
keywords: Breast; Magnetic resonance imaging; Ultrasonography