title: [Haemophilus influenzae type b meningitis in a vaccinated, immunocompetent infant with reactive arthritis].
abstract: Due to the excellent immunogenicity of the Haemophilus influenzae type b (Hib) conjugate vaccines, vaccine failures are rarely seen in patients following the recommended national immunization programmes. We present an infant with Hib meningitis despite relevant prophylaxis, without known risk factors such as medical co-morbidity, immunosuppression, immunoglobulin deficiency or prematurity. Later, a reactive arthritis developed. In conclusion, Hib-meningitis can occur in vaccinated, immunocompetent patients, and antibiotics covering Hib should be chosen in patients presenting with meningitis.
authors.affiliation: Pædiatrisk Afdeling, Næstved Sygehus, Ringstedgade 61, 4700 Næstved. kristinnystrup@gmail.com.
authors.forename: Kristin Brønnum
authors.initials: KB
authors.lastname: Nystrup
authors.forename: Line Kønig
authors.initials: LK
authors.lastname: Wilms
mesh_terms: D016918:Arthritis, Reactive / Q000382:microbiology; D016667:Bacterial Capsules / Q000276:immunology; D005260:Female; D018073:Haemophilus Vaccines / Q000276:immunology; D006801:Humans; D007223:Infant; D008583:Meningitis, Haemophilus / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D017211:Treatment Failure; D018074:Vaccines, Conjugate / Q000276:immunology
chemical_list: D018073:Haemophilus Vaccines; C044237:Haemophilus influenzae type b polysaccharide vaccine; D018074:Vaccines, Conjugate