title: General and chemoselective bisphosphonylation of secondary and tertiary amides.
abstract: With Tf2O as the activation reagent, a mild and general method has been developed for the bisphosphonylation of both secondary and tertiary amides. The protocol is highly efficient and chemoselective, and it tolerates a number of sensitive functional groups such as cyano, ester, and aldehyde groups.
authors.affiliation: Department of Chemistry, Fujian Provincial Key Laboratory of Chemical Biology, College of Chemistry and Chemical Engineering, and Collaborative Innovation Centre of Chemistry for Energy Materials, Xiamen University , Xiamen, Fujian 361005, P. R. China.
authors.forename: Ai-E
authors.initials: AE
authors.lastname: Wang
authors.forename: Zong
authors.initials: Z
authors.lastname: Chang
authors.forename: Wei-Ting
authors.initials: WT
authors.lastname: Sun
authors.forename: Pei-Qiang
authors.initials: PQ
authors.lastname: Huang
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D005663:Furans / Q000737:chemistry*; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000737:chemistry*; D013449:Sulfonamides / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D000577:Amides; D005663:Furans; D009943:Organophosphorus Compounds; D013449:Sulfonamides; C474725:triflic anhydride