title: Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia.
abstract: Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), α-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity.
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
authors.forename: Essam
authors.initials: E
authors.lastname: Abdel-Sattar
authors.affiliation: Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt ; Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
authors.forename: Dina
authors.initials: D
authors.lastname: Abou-Hussein
authors.affiliation: University of Münster, Institute of Pharmaceutical Biology and Phytochemistry, Hittorfstraße 56, D-48149 Münster, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Petereit
keywords: Cervical adenocarcinoma; Euphorbia ammak; euphol