title: Pulmonary hypertension in POEMS syndrome: resolution following radiotherapy.
abstract: Pulmonary hypertension (PH) is defined by the presence of a mean pulmonary artery pressure (mPAP) ≥25 mmHg. It may be idiopathic or arise as a consequence of a number of diverse conditions. PH has been reported in association with POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes), with reversal following systemic treatment with corticosteroids. We report a case of pulmonary hypertension associated with POEMS syndrome treated with radical radiotherapy locally to bone lesions with resolution of systemic disease.
authors.affiliation: Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United Kingdom.
authors.forename: Melanie J
authors.initials: MJ
authors.lastname: Brewis
authors.affiliation: Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United Kingdom.
authors.forename: Alistair C
authors.initials: AC
authors.lastname: Church
authors.affiliation: Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United Kingdom.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Peacock
authors.affiliation: Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United Kingdom.
authors.forename: Stephen
authors.initials: S
authors.lastname: Thomson
authors.affiliation: Department of Haematology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom.
authors.forename: Jane
authors.initials: J
authors.lastname: Tighe
authors.affiliation: Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United Kingdom.
authors.forename: Martin K
authors.initials: MK
authors.lastname: Johnson
keywords: bosentan; plasmacytoma; sildenafil