title: Finite element analysis for edge-to-edge technique to treat post-mitral valve repair systolic anterior motion.
abstract: Systolic anterior motion of the mitral valve is an uncommon complication of mitral valve repair, which requires immediate supplementary surgical action. Edge-to-edge suture is considered as an effective technique to treat post-mitral valve repair systolic anterior motion by clinical researchers. However, the fundamentals and quantitative analysis are vacant to validate the effectiveness of the additional edge-to-edge surgery to repair systolic anterior motion. In the present work, finite element models were developed to simulate a specific clinical surgery for patients with posterior leaflet prolapse, so as to analyze the edge-to-edge technique quantificationally. The simulated surgery procedure concluded several actions such as quadrangular resection, mitral annuloplasty and edge-to-edge suture. And the simulated results were compared with echocardiography and measurement data of the patients under the mitral valve surgery, which shows good agreement. The leaflets model with additional edge-to-edge suture has a shorter mismatch length than that of the model merely under quadrangular resection and mitral annuloplasty actions at systole, which assures a better coaptation status. The stress on the leaflets after edge-to-edge suture is lessened as well.
authors.affiliation: Applied Mathematics School, Xiamen University of Technology, Xiamen, People's Republic of China. Cognitive Science Department, Xiamen University, Xiamen, People's Republic of China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhong
authors.affiliation: Software School, Xiamen University, Xiamen, People's Republic of China.
authors.forename: Wenhua
authors.initials: W
authors.lastname: Zeng
authors.affiliation: Computer Science Department, Xiamen University, Xiamen, People's Republic of China.
authors.forename: Xiaoyang
authors.initials: X
authors.lastname: Huang
authors.affiliation: Computer Science Department, Xiamen University, Xiamen, People's Republic of China.
authors.forename: Xiaojia
authors.initials: X
authors.lastname: Zhao
mesh_terms: D003198:Computer Simulation; D020342:Finite Element Analysis; D006325:Heart Atria / Q000473:pathology; D006349:Heart Valve Diseases / Q000209:etiology* / Q000628:therapy*; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D008943:Mitral Valve / Q000601:surgery*; D058386:Mitral Valve Annuloplasty / Q000009:adverse effects*; D013314:Stress, Mechanical; D013599:Systole; D013997:Time Factors