title: Rh(I)-catalyzed benzo/[7+1] cycloaddition of cyclopropyl-benzocyclobutenes and CO by merging thermal and metal-catalyzed C-C bond cleavages.
abstract: A Rh-catalyzed benzo/[7+1] cycloaddition of cyclopropyl-benzocyclobutenes (CP-BCBs) and CO to benzocyclooctenones has been developed. In this reaction, CP-BCB acts as a benzo/7-C synthon and the reaction involves two C-C bond cleavages: a thermal electrocyclic ring-opening of the four-membered ring in CP-BCB and a Rh-catalyzed C-C cleavage of the cyclopropane ring.
authors.affiliation: Beijing National Laboratory of Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry, Peking University, Beijing, 100871 (P. R. China), Fax: (+86) 10-6275-1708 http://www.chem.pku.edu.cn/zxyu/index.htm.
authors.forename: Xu-Fei
authors.initials: XF
authors.lastname: Fu
authors.forename: Yu
authors.initials: Y
authors.lastname: Xiang
authors.forename: Zhi-Xiang
authors.initials: ZX
authors.lastname: Yu
mesh_terms: D002384:Catalysis; D061565:Cycloaddition Reaction / Q000379:methods*; D015394:Molecular Structure; D011083:Polycyclic Compounds / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
chemical_list: D011083:Polycyclic Compounds; C079040:benzocyclobutene; D012238:Rhodium
keywords: benzo/[7+1]; benzocyclobutene; carbonylation; eight-membered ring; rhodium