title: Coupling carbon nanotube film microextraction with desorption corona beam ionization for rapid analysis of Sudan dyes (I-IV) and Rhodamine B in chilli oil.
abstract: A rapid analysis method by coupling carbon nanotube film (CNTF) microextraction with desorption corona beam ionization (DCBI) was developed for the determination of Sudan dyes (I-IV) and Rhodamine B in chilli oil samples. Typically, CNTF was immersed into the diluted solution of chilli oil for extraction, which was then placed directly under the visible plasma beam tip of the DCBI source for desorption and ionization. Under optimized conditions, five dyes were simultaneously determined using this method. Results showed that the analytes were enriched by the CNTF through the π-π interactions, and the proposed method could significantly improve the sensitivities of these compounds, compared to the direct analysis by DCBI-MS/MS. The method with a linear range of 0.08-12.8 μg g(-1) and good linear relationships (R(2) > 0.93) in a multiple reaction monitoring (MRM) mode was developed. Satisfactory reproducibility was achieved. Relative standard deviations (RSDs) were less than 20.0%. The recoveries ranged from 80.0 to 110.0%, and the limits of detection (LODs) were in the range of 1.4-21 ng g(-1). Finally, the feasibility of the method was further exhibited by the determination of five illegal dyes in chilli powder. These results demonstrate that the proposed method consumes less time and solvent than conventional HPLC-based methods and avoids the contamination of chromatographic column and ion source from non-volatile oil. With the help of a 72-well shaker, multiple samples could be treated simultaneously, which ensures high throughput for the entire pretreatment process. In conclusion, it provides a rapid and high-throughput approach for the determination of such illicit additions in chilli products.
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Department of Chemistry, Wuhan University, Wuhan 430072, China. yqfeng@whu.edu.cn.
authors.forename: Di
authors.initials: D
authors.lastname: Chen
authors.forename: Yun-Qing
authors.initials: YQ
authors.lastname: Huang
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: He
authors.forename: Zhi-Guo
authors.initials: ZG
authors.lastname: Shi
authors.forename: Yu-Qi
authors.initials: YQ
authors.lastname: Feng
mesh_terms: D001391:Azo Compounds / Q000032:analysis; D002212:Capsicum / Q000737:chemistry*; D004396:Coloring Agents / Q000032:analysis*; D005503:Food Additives / Q000032:analysis*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010938:Plant Oils / Q000032:analysis*; D052617:Solid Phase Microextraction / Q000379:methods*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
chemical_list: D001391:Azo Compounds; D004396:Coloring Agents; D005503:Food Additives; D037742:Nanotubes, Carbon; D010938:Plant Oils; C033003:sudan red; C033006:sudan III