title: Half-and-half nails in a pediatric patient after chemotherapy.
abstract: Half-and-half nail, characterized by a reddish brown distal band with a sharply demarcated white proximal band, is a specific manifestation of chronic kidney disease, but it is unusual to occur after chemotherapy. We report a seven-year-old girl who developed half-and-half nails in her fingers one month after treatment with modified Berlin-Frankfurt-Munster protocol followed by maintenance therapy with oral methotrexate and 6-mercaptopurine for pre-B acute lymphoblastic leukemia.
authors.affiliation: a Department of Dermatology , Ataturk Research and Training Hospital , Izmir , Turkey and.
authors.forename: Fatma Sule
authors.initials: FS
authors.lastname: Afsar
authors.affiliation: b Department of Hematology , Dr. Behcet Uz Children's Hospital , Izmir , Turkey.
authors.forename: Gulcihan
authors.initials: G
authors.lastname: Ozek
authors.affiliation: b Department of Hematology , Dr. Behcet Uz Children's Hospital , Izmir , Turkey.
authors.forename: Canan
authors.initials: C
authors.lastname: Vergin
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001215:Asparaginase / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D003630:Daunorubicin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009260:Nail Diseases / Q000139:chemically induced* / Q000175:diagnosis; D009262:Nails / Q000187:drug effects*; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy; D011241:Prednisone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D014750:Vincristine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D001215:Asparaginase; D011241:Prednisone; D003630:Daunorubicin
keywords: Chemotherapy; half-and-half nail; nail changes