title: [Proportion and related influencing factors of HIV-infected individuals that rejecting the antiretroviral therapy among all the HIV infections, Dehong prefecture, Yunnan province].
abstract: OBJECTIVE
  To examine the proportion and influencing factors on HIV-infected individuals who rejecting the antiretroviral therapy among all the HIV positives, in Dehong prefecture, Yunnan province.
  
  
  METHODS
  A cross-sectional analysis was conducted on all the local HIV-infected survivals aged over 16 year old who refused to receive antiretroviral therapy (ART) by the end of 2013 in Dehong prefecture.
  
  
  RESULTS
  The proportion of those rejecting the ART among HIV-infected survivals and aged over 16 years old in Dehong prefecture, was 7.4% (605/8 136). Factors related to the 'rejection' among the 605 refusals would include: being male (72.9%), aged 31-45 years (57.2%), peasants (75.4%), married (52.2%), with minor ethnicity (41.3%), illiterate or only having primary school education (58.7%), infected through sexual contacts (61.2%), and with CD4(+)T cell counts >350 cells/mm(3) (66.6%). Data from the multiple logistic regression analysis indicated that rejecting the ART was significantly associated with areas, gender, age, ethnicity and CD4(+)T cell counts of the HIV patients. Those who were from Yingjiang county, female, aged 31-45 years old had lower proportions of ART refusals than those who were from Ruili city, male, aged ≤30 year old. Those who were of Dai minority and had no records on CD4(+)T cell counts, had higher proportions of ART refusals than those who were of Han ethnicity and had CD4(+)T cell counts ≤350 cells/mm(3). Reasons for the 605 HIV-infected patients with rejection to the ART would include fear of disclosure of HIV infection status (84, 13.9%), misunderstandings of the effectiveness and side effects of ART (111, 18.3%), self-realized wellness(340, 56.2%) and others (70, 11.6%). Of them, reasons for the 181 patients with CD4(+)T cell counts ≤350 cells/mm(3) that rejecting ART would include fearfulness on the disclosure of HIV infection status(40, 22.1%), misunderstandings of the effectiveness and side effects of ART (36, 19.9%), self-realized wellness (84, 46.4%) and others (21, 11.6%). Among those who rejected ART, reasons for that would vary by areas, gender, age, marital status and routes of HIV transmission, according to the results from Chi-squared tests.
  
  
  CONCLUSIONS
  A substantial proportion of HIV-infected individuals rejected ART in Dehong prefecture of Yunnan province. It was urgently needed to enhance health education programs of ART tailored for those HIV-infected patients, according to different characteristics and reasons for rejection, so as to promote the ART in this prefecture.
authors.affiliation: Dehong Prefecture Center for Disease Control and Prevention, Yunnan 678400, China.
authors.forename: Shitang
authors.initials: S
authors.lastname: Yao
authors.affiliation: Dehong Prefecture Center for Disease Control and Prevention, Yunnan 678400, China.
authors.forename: Runhua
authors.initials: R
authors.lastname: Ye
authors.affiliation: Dehong Prefecture Center for Disease Control and Prevention, Yunnan 678400, China.
authors.forename: Yuecheng
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Dehong Prefecture Center for Disease Control and Prevention, Yunnan 678400, China.
authors.forename: Lifen
authors.initials: L
authors.lastname: Xiang
authors.affiliation: Dehong Prefecture Center for Disease Control and Prevention, Yunnan 678400, China.
authors.forename: Jibao
authors.initials: J
authors.lastname: Wang
authors.affiliation: Mangshi City Center for Disease Control and Prevention.
authors.forename: Benli
authors.initials: B
authors.lastname: Du
authors.affiliation: Longchuan County Center for Disease Control and Prevention.
authors.forename: Wenxiang
authors.initials: W
authors.lastname: Han
authors.affiliation: Yingjiang County Center for Disease Control and Prevention.
authors.forename: Yongying
authors.initials: Y
authors.lastname: Nie
authors.affiliation: Ruili City Center for Disease Control and Prevention.
authors.forename: Zhongju
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Lianghe County Center for Disease Control and Prevention.
authors.forename: Weimei
authors.initials: W
authors.lastname: Li
authors.affiliation: Department of Epidemiology and Key Laboratory of Public Health Safety of Ministry of Education, School of Public Health, Fudan University. Email: nhe@shmu.edu.cn.
authors.forename: Na
authors.initials: N
authors.lastname: He
authors.affiliation: Dehong Prefecture Center for Disease Control and Prevention, Yunnan 678400, China. Email: dhduansong@sina.com.cn.
authors.forename: Song
authors.initials: S
authors.lastname: Duan
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D002681:China; D003430:Cross-Sectional Studies; D005006:Ethnicity; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006266:Health Education; D006301:Health Services Needs and Demand; D006801:Humans; D008297:Male; D017533:Marital Status; D008393:Marriage; D008875:Middle Aged; D008913:Minority Groups; D012725:Sexual Behavior; D016312:Treatment Refusal
chemical_list: D044966:Anti-Retroviral Agents