title: Stem cell transplantation for treating Duchenne muscular dystrophy: A Web of Science-based literature analysis.
abstract: OBJECTIVE
  To identify global research trends in stem cell transplantation for treating Duchenne muscular dystrophy using a bibliometric analysis of Web of Science.
  
  
  METHODS
  We performed a bibliometric analysis of studies on stem cell transplantation for treating Duchenne muscular dystrophy from 2002 to 2011 retrieved from Web of Science.
  
  
  METHODS
  
  
  
  METHODS
  (a) peer-reviewed published articles on stem cell transplantation for treating Duchenne muscular dystrophy indexed in Web of Science; (b) original research articles, reviews, meeting abstracts, proceedings papers, book chapters, editorial material, and news items; and (c) publication between 2002 and 2011.
  
  
  METHODS
  (a) articles that required manual searching or telephone access; (b) documents that were not published in the public domain; and (c) corrected papers.
  
  
  METHODS
  (1) Annual publication output; (2) distribution according to subject areas; (3) distribution according to journals; (4) distribution according to country; (5) distribution according to institution; (6) distribution according to institution in China; (7) distribution according to institution that cooperated with Chinese institutions; (8) top-cited articles from 2002 to 2006; (9) top-cited articles from 2007 to 2011.
  
  
  RESULTS
  A total of 318 publications on stem cell transplantation for treating Duchenne muscular dystrophy were retrieved from Web of Science from 2002 to 2011, of which almost half derived from American authors and institutes. The number of publications has gradually increased over the past 10 years. Most papers appeared in journals with a focus on gene and molecular research, such as Molecular Therapy, Neuromuscular Disorders, and PLoS One. The 10 most-cited papers from 2002 to 2006 were mostly about different kinds of stem cell transplantation for muscle regeneration, while the 10 most-cited papers from 2007 to 2011 were mostly about new techniques of stem cell transplantation for treating Duchenne muscular dystrophy.
  
  
  CONCLUSIONS
  The publications on stem cell transplantation for treating Duchenne muscular dystrophy were relatively few. It also needs more research to confirm that stem cell therapy is a reliable treatment for Duchenne muscular dystrophy.
authors.affiliation: Cell Therapy Center, Chinese PLA 463 Hospital, Shenyang 110042, Liaoning Province, China.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Yang
keywords: Becker muscular dystrophy; Duchenne muscular dystrophy; cell transplantation; dystrophin gene; exon skipping; motor function; myoblast; neural regeneration; pseudohypertrophic muscular dystrophy; regenerative myogenesis; stem cell