title: Comparison of effects of labetalol and nitroglycerine on intraoperative blood loss and surgical field quality in rhinoplasty surgery.
abstract: BACKGROUND
  Rhinoplasty is one of the most common surgeries of the plastic surgery and as well as ear, throat and nose. Intra-operative bleeding during surgery is one of the most important factors that may impair the surgeon's job. Providing a clean blood-free surgical filed makes the operation faster, easier and with a better quality. One way to achieve this goal is to induce hypotension. This study aimed to compare the impacts and outcomes of administration of labetalol or nitroglycerin for this purpose.
  
  
  METHODS
  In this randomized clinical trial, 60 ASA I and ASA II patients who were referred for rhinoplasty were enrolled. Patients were randomly assigned to two groups. Labetalol was given to the first and nitroglycerin to the second group of patients. Blood pressure and the amount of intra-operative bleeding during surgery and surgeon satisfaction were measured.
  
  
  RESULTS
  The average age of patients was 25.9±7.52 years. The average amount of bleeding among all patients was 117.87±324.86 ml, and the average quality of the surgical site was 1.65±4.48, considering all patients. The average quality and average surgical site bleeding between the two groups was not significant.
  
  
  CONCLUSIONS
  There was a little difference between labetalol and nitroglycerine on the effect of intraoperative blood loss and surgical field quality in rhinoplasty surgery.
authors.affiliation: Department of Anesthesiology and Intensive Care, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mohamad Reza
authors.initials: MR
authors.lastname: Hadavi
authors.affiliation: Department of Anesthesiology and Intensive Care, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Yadollah
authors.initials: Y
authors.lastname: Zarei
authors.affiliation: Department of Anesthesiology and Intensive Care, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Shojaolhagh
authors.initials: S
authors.lastname: Tarogh
keywords: Intraoperative bleeding; Labetalol; Nitroglycerin; Rhinoplasty