title: [Evaluation of the efficacy and the limitation of ultrasound-guided core-needle biopsy, core-needle aspiration and fine-needle aspiration in micro-nodules of thyroid].
abstract: OBJECTIVE
  To evaluate the efficacy and the limitation of ultrasound-guided core-needle biopsy, ultrasound-guided core-needle aspiration and ultrasound-guided fine-needle aspiration in micro-nodules of thyroid.
  
  
  METHODS
  A retrospective was performed in 92 patients with suspectable malignent micro-nodules in thyroid. Of them, 52 patients underwent US-CNB and US-FNA and 40 patients underwent US-CNA and US-FNA. The diagnoses for the micro-nodules were identified by histopathlogical examination after surgery.
  
  
  RESULTS
  Among 52 cases with both US-CNB and US-FNA, 41 got nondiagnostic US-CNB and 11 cases successfully got the correct diagnoses of US-CNB; 6 cases got the incorrect diagnosis of US-FNA and 46 cases got the correct diagnosis of US-FNA. Of 40 cases with US-CNA and US-FNA, unsatisfactory specimen of US-CNA occurred in 14 cases and satisfactory specimen of US-CNA were got in 26 cases; unsatisfactory specimen of US-FNA occurred in 4 cases and satisfactory specimen of US-FNA. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of US-FNA in 92 cases for the diagnosis of malignancy were 93.4%, 86.7%, 97.3%, 72.2% and 92.3%, respectively.
  
  
  CONCLUSIONS
  US-FNA is the most valuable method for the diagnosis of suspectable malignent micro-nodules in thyroid before operation.
authors.affiliation: Department of Diagnostic Imaging, Cancer Hospital, Chinese Academy of Sciences, Peking Union Medical College, Beijing 100021, China.
authors.forename: Shaohang
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Department of Diagnostic Imaging, Cancer Hospital, Chinese Academy of Sciences, Peking Union Medical College, Beijing 100021, China. Email: niulijuan8197@126.com.
authors.forename: Lijuan
authors.initials: L
authors.lastname: Niu
mesh_terms: D044963:Biopsy, Fine-Needle / Q000379:methods*; D001707:Biopsy, Needle; D006801:Humans; D009339:Needles; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013964:Thyroid Neoplasms; D016606:Thyroid Nodule / Q000000981:diagnostic imaging / Q000601:surgery*; D014463:Ultrasonography