title: Towards model-based adaptive optics optical coherence tomography.
abstract: The transfer function for optical wavefront aberrations in single-mode fiber based optical coherence tomography is determined. The loss in measured OCT signal due to optical wavefront aberrations is quantified using Fresnel propagation and the calculation of overlap integrals. A distinction is made between a model for a mirror and a scattering medium model. The model predictions are validated with measurements on a mirror and a scattering medium obtained with an adaptive optics optical coherence tomography setup. Furthermore, a one-step defocus correction, based on a single A-scan measurement, is derived from the model and verified. Finally, the pseudo-convex structure of the optical coherence tomography transfer function is validated with the convergence of a hill climbing algorithm. The implications of this model for wavefront sensorless aberration correction are discussed.
authors.forename: Hans R G W
authors.initials: HR
authors.lastname: Verstraete
authors.forename: Barry
authors.initials: B
authors.lastname: Cense
authors.forename: Rolf
authors.initials: R
authors.lastname: Bilderbeek
authors.forename: Michel
authors.initials: M
authors.lastname: Verhaegen
authors.forename: Jeroen
authors.initials: J
authors.lastname: Kalkman
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D017076:Computer-Aided Design; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005246:Feedback; D007089:Image Enhancement / Q000295:instrumentation*; D007909:Lenses; D008027:Light; D008962:Models, Theoretical; D012542:Scattering, Radiation; D041623:Tomography, Optical Coherence / Q000295:instrumentation*