title: A simple modular aptasensor platform utilizing cucurbit[7]uril and a ferrocene derivative as an ultrastable supramolecular linker.
abstract: A simple modular aptamer-based sensor (aptasensor) platform was prepared by combining the merits of the rapid and efficient preparation of a self-assembled monolayer of cucurbit[7]uril (CB[7] SAM) and the strong and specific binding affinity of CB[7] to ferrocenemethylammonium (FA), as an ultrastable supramolecular linker, to immobilize aptamers on CB[7] SAM.
authors.affiliation: Center for Self-assembly and Complexity, Institute for Basic Science (IBS), Pohang, 790-784, Republic of Korea.
authors.forename: Don-Wook
authors.initials: DW
authors.lastname: Lee
authors.forename: Kyeng Min
authors.initials: KM
authors.lastname: Park
authors.forename: Bokyoung
authors.initials: B
authors.lastname: Gong
authors.forename: Dinesh
authors.initials: D
authors.lastname: Shetty
authors.forename: Jayshree K
authors.initials: JK
authors.lastname: Khedkar
authors.forename: Kangkyun
authors.initials: K
authors.lastname: Baek
authors.forename: Jeehong
authors.initials: J
authors.lastname: Kim
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Ryu
authors.forename: Kimoon
authors.initials: K
authors.lastname: Kim
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques; D001952:Bridged-Ring Compounds / Q000737:chemistry*; D004247:DNA / Q000737:chemistry; D005296:Ferrous Compounds / Q000737:chemistry*; D006046:Gold / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry*; D013917:Thrombin / Q000737:chemistry; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
chemical_list: D052157:Aptamers, Nucleotide; D001952:Bridged-Ring Compounds; D004247:DNA; D005296:Ferrous Compounds; D006046:Gold; D007093:Imidazoles; D013917:Thrombin; C456276:cucurbit(7)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils