title: Supramolecular chemical shift reagents inducing conformational transitions: NMR analysis of carbohydrate homooligomer mixtures.
abstract: We introduce the concept of supramolecular chemical shift reagents as a tool to improve signal resolution for the NMR analysis of homooligomers. Non-covalent interactions with the shift reagent can constrain otherwise flexible analytes inducing a conformational transition that results in signal separation. Here we use this approach for the quantitative analysis of a complex homooligomeric glycan mixture.
authors.affiliation: Carlsberg Laboratory, Gamle Carlsberg Vej 10, Copenhagen V 1799, Denmark. sophie.beeren@carlsberglab.dk.
authors.forename: Sophie R
authors.initials: SR
authors.lastname: Beeren
authors.forename: Sebastian
authors.initials: S
authors.lastname: Meier