title: Base-promoted coupling of carbon dioxide, amines, and N-tosylhydrazones: a novel and versatile approach to carbamates.
abstract: A base-promoted three-component coupling of carbon dioxide, amines, and N-tosylhydrazones has been developed. The reaction is suggested to proceed via a carbocation intermediate and constitutes an efficient and versatile approach for the synthesis of a wide range of organic carbamates. The advantages of this method include the use of readily available substrates, excellent functional group tolerance, wide substrate scope, and a facile work-up procedure.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640 (P.R. China).
authors.forename: Wenfang
authors.initials: W
authors.lastname: Xiong
authors.forename: Chaorong
authors.initials: C
authors.lastname: Qi
authors.forename: Haitao
authors.initials: H
authors.lastname: He
authors.forename: Lu
authors.initials: L
authors.lastname: Ouyang
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
mesh_terms: D000588:Amines / Q000737:chemistry*; D002219:Carbamates / Q000138:chemical synthesis*; D002245:Carbon Dioxide / Q000737:chemistry*; D006835:Hydrazones / Q000737:chemistry*
chemical_list: D000588:Amines; D002219:Carbamates; D006835:Hydrazones; D002245:Carbon Dioxide
keywords: amines; carbamates; carbon dioxide; multicomponent reactions; tosylhydrazones