title: Primary esophageal mucosa-associated lymphoid tissue lymphoma diagnosed by using stacked forceps biopsy.
abstract: Non-Hodgkin lymphoma involving the esophagus is very rare. Only a few cases have been reported in the English literature to date, and it accounts for less than 1% of all cases of gastrointestinal lymphoma. As this malignancy manifests as a submucosal tumor, pathological diagnosis by using a simple endoscopic biopsy alone is difficult. Therefore, surgical biopsy, endoscopic mucosal resection, and endoscopic ultrasound-guided fine-needle aspiration have been used in most cases. Herein, we report a case of esophageal mucosa-associated lymphoid tissue lymphoma in a 49-year-old man, which involved the use of a stacked forceps biopsy to obtain adequate samples for pathological analysis; the use of the stacked forceps biopsy method is unlike those used in previous cases. The patient received cyclophosphamide, vincristine, and prednisolone chemotherapy; he achieved a complete response. In addition, we review the literature relevant to this case.
authors.affiliation: Department of Internal Medicine, Gangneung Asan Medical Center, University of Ulsan College of Medicine, Gangneung, South Korea.
authors.forename: D S
authors.initials: DS
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Gangneung Asan Medical Center, University of Ulsan College of Medicine, Gangneung, South Korea.
authors.forename: Y C
authors.initials: YC
authors.lastname: Ahn
authors.affiliation: Department of Pathology, Gangneung Asan Medical Center, University of Ulsan College of Medicine, Gangneung, South Korea.
authors.forename: D W
authors.initials: DW
authors.lastname: Eom
authors.affiliation: Department of Internal Medicine, Gangneung Asan Medical Center, University of Ulsan College of Medicine, Gangneung, South Korea. sangjin@gnah.co.kr.
authors.forename: S J
authors.initials: SJ
authors.lastname: Lee
mesh_terms: D001706:Biopsy / Q000295:instrumentation* / Q000379:methods; D000071041:Esophageal Mucosa / Q000473:pathology; D004938:Esophageal Neoplasms / Q000473:pathology*; D006801:Humans; D008221:Lymphoid Tissue / Q000473:pathology; D018442:Lymphoma, B-Cell, Marginal Zone / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013525:Surgical Instruments