title: A case of gingival candidiasis with bone destruction on gastric cancer patient receiving cytotoxic chemotherapy.
abstract: We herein report a case of gingival candidiasis in an advanced gastric cancer patient while receiving palliative cytotoxic chemotherapy. A 46-year-old male patient admitted to our hospital for known advanced gastric cancer with newly developed multiple liver metastases. While receiving 2nd line cytotoxic chemotherapy with 5FU, leucovorin, and paclitxel, he complained of gingival swelling accompanied by pain and whitish plaque. Due to lack of response to the conservative oral care, incisional biopsy of gingiva was done and the pathology confirmed gingival candidiasis. Although the lesion healed apparently after two-week antifungal therapy, pain as well as bony destruction remains. By presenting this case report, we intend to emphasize the immunocompromising effect of cancer while being on systemic chemotherapy.
authors.affiliation: Department of Internal Medicine, Konyang University Hospital, Gasuwon-dong, Seo-gu, Daejeon 302-718, Republic of Korea.
authors.forename: Seungtaek
authors.initials: S
authors.lastname: Lim
authors.affiliation: Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea.
authors.forename: Tae-Jun
authors.initials: TJ
authors.lastname: Kil
authors.affiliation: Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea ; Yonsei Cancer Center, Yonsei Cancer Research Institute, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea ; Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea.
authors.forename: Hye Ryun
authors.initials: HR
authors.lastname: Kim
authors.affiliation: Department of Oral Pathology, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea.
authors.forename: Seonhui
authors.initials: S
authors.lastname: Han
authors.affiliation: Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea ; Yonsei Cancer Center, Yonsei Cancer Research Institute, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea ; Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Republic of Korea.
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Rha