title: Subthreshold micropulse yellow laser (577 nm) in chronic central serous chorioretinopathy: safety profile and treatment outcome.
abstract: OBJECTIVE
  To assess the safety and efficacy of a single session of subthreshold micropulse (SM) yellow laser (577 nm) in the treatment of chronic central serous chorioretinopathy (CSCR).
  
  
  METHODS
  This was a retrospective analysis of 15 eyes of 13 patients with CSCR of >3 months duration who had been treated with SM yellow laser (577 nm). All patients had been treated using multiple spots of laser with a duty cycle of 10% over areas of focal and diffuse leak, as seen on fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA). Reduction in subretinal fluid height on spectral domain optical coherence tomography (SD-OCT) was used to measure the response to treatment.
  
  
  RESULTS
  The mean follow-up was at 8 weeks (4-19 weeks). All eyes responded to treatment. The mean subretinal fluid height pre and post treatment was 232 and 49 μm, respectively, showing a 79% average reduction (P<0.001) in fluid height. There was no evidence of retinal pigment epithelium or retinal damage on SD-OCT, FFA, or fundus autofluorescence. Median visual improvement was one line on Snellen's visual acuity chart (P=0.015). Microperimetry was performed in eight eyes of which six eyes (75%) showed an improvement in the threshold values post treatment.
  
  
  CONCLUSIONS
  SM yellow laser is an effective treatment option for chronic CSCR.
authors.affiliation: Department of Vitreoretina Services, Narayana Nethralaya, Bangalore, India.
authors.forename: N K
authors.initials: NK
authors.lastname: Yadav
authors.affiliation: Department of Vitreoretina Services, Narayana Nethralaya, Bangalore, India.
authors.forename: C
authors.initials: C
authors.lastname: Jayadev
authors.affiliation: Department of Vitreoretina Services, Narayana Nethralaya, Bangalore, India.
authors.forename: A
authors.initials: A
authors.lastname: Mohan
authors.affiliation: Department of Vitreoretina Services, Narayana Nethralaya, Bangalore, India.
authors.forename: P
authors.initials: P
authors.lastname: Vijayan
authors.affiliation: Department of Vitreoretina Services, Narayana Nethralaya, Bangalore, India.
authors.forename: R
authors.initials: R
authors.lastname: Battu
authors.affiliation: Department of Vitreoretina Services, Narayana Nethralaya, Bangalore, India.
authors.forename: S
authors.initials: S
authors.lastname: Dabir
authors.affiliation: Department of Vitreoretina Services, Narayana Nethralaya, Bangalore, India.
authors.forename: B
authors.initials: B
authors.lastname: Shetty
authors.affiliation: Department of Vitreoretina Services, Narayana Nethralaya, Bangalore, India.
authors.forename: R
authors.initials: R
authors.lastname: Shetty
mesh_terms: D000328:Adult; D056833:Central Serous Chorioretinopathy / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D002908:Chronic Disease; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D017075:Laser Coagulation / Q000379:methods*; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D058471:Subretinal Fluid / Q000378:metabolism; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D058609:Visual Field Tests; D014794:Visual Fields / Q000502:physiology
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green