title: Clinical applications of surgical adhesives and sealants.
abstract: In the United States and Europe, the number of topical adhesives, surgical sealants, and hemostats approved for use in the surgical setting is ever expanding although no single device fills all medical and surgical needs to replace sutures. As more surgical procedures are performed through laparoscopic and robotic approaches, these devices are becoming more important, and current research is focused on solving the limitations of conventional wound treatments. This review article discusses clinical applications of various biologically derived and synthetic products that are currently available to surgeons and those that are in development.
authors.affiliation: Department of Bioengineering, Clemson University, Clemson, South Carolina.
authors.forename: Lindsey
authors.initials: L
authors.lastname: Sanders
authors.affiliation: Clemson University.
authors.forename: Jiro
authors.initials: J
authors.lastname: Nagatomi
mesh_terms: D003094:Collagen; D003487:Cyanoacrylates; D004338:Drug Combinations; D006489:Hemostatic Techniques; D006801:Humans; D009842:Oligopeptides; D011092:Polyethylene Glycols; D011506:Proteins; D013917:Thrombin; D014014:Tissue Adhesives
chemical_list: C472676:Bio-glue; D003487:Cyanoacrylates; D004338:Drug Combinations; C570829:DuraSeal spinal sealant; D009842:Oligopeptides; D011506:Proteins; D014014:Tissue Adhesives; D011092:Polyethylene Glycols; D003094:Collagen; D013917:Thrombin