title: Is microcephaly a so-far unrecognized feature of XYY syndrome?
abstract: •47,XYY syndrome is a frequent sex chromosome aneuploidy.•Overview of characteristic symptoms of 47,XXY•First report of 47,XYY and microcephaly in a preterm child•Brief differential diagnosis of microcephaly.
authors.affiliation: Department of Pediatric Neurology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Nguyen-Minh
authors.affiliation: Department of Neonatology, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Bührer
authors.affiliation: Department of Pediatric Neurology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Hübner
authors.affiliation: Department of Pediatric Neurology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany ; SPZ Pediatric Neurology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany ; Institute of Neuroanatomy and Cell Biology, Charité - Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10115 Berlin, Germany.
authors.forename: Angela M
authors.initials: AM
authors.lastname: Kaindl
keywords: 47,XYY syndrome; Delayed speech development; HAWIK-IV, Hamburg-Wechsler Intelligence test for Children; Hyperactivity; Impulsiveness; Mental retardation; Microcephaly; NCBI, National Center for Biotechnology Information; OFC, occipitofrontal head circumference; OMIM, Online Mendilian Inheritance in Man; array CGH, array comparative genomic hybridization