title: Olfactory disruption: toward controlling important insect vectors of disease.
abstract: Chemical repellents are used to decrease contacts between insect disease vectors and their hosts, thus reducing the probability of disease transmission. The molecular mechanisms by which repellents have their effects are poorly understood and remain a controversial topic. Here, we present recent results of studies aimed at a more thorough understanding of the mode of action of repellents and discuss the implications of these findings for future research and development of novel or improved repellents.
authors.affiliation: United States Department of Agriculture, Beltsville Agricultural Research Center, Invasive Insect Biocontrol and Behavior Laboratory, Beltsville, Maryland, USA.
authors.forename: Jackson T
authors.initials: JT
authors.lastname: Sparks
authors.affiliation: United States Department of Agriculture, Beltsville Agricultural Research Center, Invasive Insect Biocontrol and Behavior Laboratory, Beltsville, Maryland, USA.
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Bohbot
authors.affiliation: United States Department of Agriculture, Beltsville Agricultural Research Center, Invasive Insect Biocontrol and Behavior Laboratory, Beltsville, Maryland, USA. Electronic address: joseph.dickens@ars.usda.gov.
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Dickens
mesh_terms: D000818:Animals; D061046:Biological Control Agents; D003140:Communicable Disease Control; D006801:Humans; D007302:Insect Repellents / Q000627:therapeutic use*; D007303:Insect Vectors / Q000187:drug effects / Q000502:physiology*; D000857:Olfaction Disorders / Q000517:prevention & control*
chemical_list: D061046:Biological Control Agents; D007302:Insect Repellents
keywords: DEET; Disease vector; Gustation; Insect; Molecular receptor; Mosquito; Olfaction; Repellent