title: Alternative screening for women with dense breasts: breast-specific gamma imaging (molecular breast imaging).
abstract: OBJECTIVE. Given mammography's limitations in evaluating dense breasts, examination with breast-specific gamma imaging (BSGI)-also called molecular breast imaging (MBI)-has been proposed. We review the literature pertinent to the performance of BSGI in patients with dense breasts. CONCLUSION. Many studies have reported the sensitivity of BSGI in finding cancers even in dense breasts. However, BSGI has not yet been validated as an effective screening tool in large prospective studies. In addition, whole-body dose remains a significant concern.
authors.affiliation: 1 Both authors: Department of Radiology, Emory University, 1365C Clifton Rd, NE, Bldg C, Ste C1104, Atlanta, GA 30322.
authors.forename: Anna
authors.initials: A
authors.lastname: Holbrook
authors.forename: Mary S
authors.initials: MS
authors.lastname: Newel
mesh_terms: D001940:Breast / Q000000981:diagnostic imaging* / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D006801:Humans; D057054:Molecular Imaging; D011877:Radionuclide Imaging; D015203:Reproducibility of Results
keywords: breast cancer; breast-specific gamma imaging (BSGI); molecular breast imaging (MBI)