title: A case of nodular regenerative hyperplasia of the liver combined with toxic hepatitis.
abstract: Nodular regenerative hyperplasia (NRH) is an uncommon liver condition characterized by diffuse transformation of the hepatic parenchyma into regenerative nodules without fibrosis. Portal vasculopathy caused by abnormal hepatic venous flow may induce hepatocyte hyperplasia, which forms regenerative nodules. Underlying diseases or certain drugs may also be the cause of NRH. This condition is often underdiagnosed as the patients remain asymptomatic until development of portal hypertension, and histopathologic confirmation by liver biopsy is the only way of making a definite diagnosis. The management mainly involves prevention and treatment of the complications of portal hypertension. The frequency of diagnosis of NRH has increased rapidly in recent years, however, only a few cases have been reported in Korea. Here, we report on a case of NRH of the liver combined with toxic hepatitis.
authors.affiliation: Departments of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
authors.forename: Sun Mi
authors.initials: SM
authors.lastname: Jin
authors.affiliation: Departments of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
authors.forename: Sang Hee
authors.initials: SH
authors.lastname: Song
authors.affiliation: Departments of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
authors.forename: Yang Hyun
authors.initials: YH
authors.lastname: Cho
authors.affiliation: Departments of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
authors.forename: Dae Kyu
authors.initials: DK
authors.lastname: Shin
authors.affiliation: Departments of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Shin
authors.affiliation: Departments of Pathology, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
authors.forename: Gwang Il
authors.initials: GI
authors.lastname: Kim
authors.affiliation: Departments of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
authors.forename: Hana
authors.initials: H
authors.lastname: Park
authors.affiliation: Departments of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
authors.forename: Kyu Sung
authors.initials: KS
authors.lastname: Rim
mesh_terms: D000410:Alanine Transaminase / Q000032:analysis; D001219:Aspartate Aminotransferases / Q000032:analysis; D001663:Bilirubin / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D004381:Duodenal Ulcer / Q000473:pathology; D016145:Endoscopy, Digestive System; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000201:enzymology / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D001663:Bilirubin