title: Aldosterone deficiency after unilateral adrenalectomy for Conn's syndrome: a case report and literature review.
abstract: BACKGROUND
  Approximately 35% of cases of Conn's syndrome (primary aldosteronism) result from a solitary functioning adrenal adenoma, and these patients are best managed by adrenalectomy. Postoperative hypoaldosteronism after unilateral adrenalectomy is uncommon.
  
  
  METHODS
  We present a case and literature review of hypoaldosteronism after unilateral adrenalectomy for Conn's syndrome, which demonstrates the insidious and sometimes delayed presentation.
  
  
  CONCLUSIONS
  In this clinical case we summarize the previously published cases of post-adrenalectomy hypoaldosteronism based on a PUBMED and EBSCOhost search of all peer-reviewed publications (original articles and reviews) on this topic. A few cases of aldosterone insufficiency post-adrenalectomy for Conn's syndrome were identified. The etiological factors for prolonged selective suppression of aldosterone secretion after unilateral adrenalectomy remain unclear.
  
  
  CONCLUSIONS
  It is important to be aware of the risk of postoperative hypoaldosteronism in this patient population. Close postoperative follow-up is necessary and strongly recommended, especially in patients with certain risk factors. Patients may need mineralocorticoid supplementation during this period.
authors.affiliation: Department of Surgery, St. Paul's Hospital, Vancouver, British Columbia, Canada.
authors.forename: Ekua
authors.initials: E
authors.lastname: Yorke
authors.affiliation: Department of Endocrinology, Surrey Memorial Hospital, Surrey, British Columbia, Canada.
authors.forename: Sara
authors.initials: S
authors.lastname: Stafford
authors.affiliation: Department of Pathology and Laboratory Medicine, St. Paul's Hospital, Vancouver, British Columbia, Canada.
authors.forename: Daniel
authors.initials: D
authors.lastname: Holmes
authors.affiliation: Department of Pathology and Laboratory Medicine, St. Paul's Hospital, Vancouver, British Columbia, Canada.
authors.forename: Sachiv
authors.initials: S
authors.lastname: Sheth
authors.affiliation: Department of Surgery, St. Paul's Hospital, Vancouver, British Columbia, Canada. Electronic address: amelck@providencehealth.bc.ca.
authors.forename: Adrienne
authors.initials: A
authors.lastname: Melck
keywords: Adrenalectomy; Aldosterone; Conn’s; Hypertension; Hypokalemia