title: Comparative histopathological characterization of prostate cancer in Saudi patients by conventional and 2005 ISUP modified gleason systems.
abstract: BACKGROUND
  The aim of this study was to compare the characterization of prostate cancer using the conventional and 2005 ISUP modified Gleason systems.
  
  
  METHODS
  The study employed samples from 40 prostate cancer patients with resection, biopsy and RP materials. The majority of cases (95%) comprised adenocarcinoma of the prostate with a modified combined Gleason score of 7 in 20 of the cases (50%).
  
  
  RESULTS
  Upgrading of Gleason scores to a score of 7 occurred in more than 45% of the cases.
  
  
  CONCLUSIONS
  The study successfully showed that by the use of the 2005 ISUP modified Gleason system, score 6 cancers decreased from 25% to 17.5% of cases, whereas score 7 cancers increased from 45% to 50%.
authors.affiliation: Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia E-mail : fsd707@gmail.com.
authors.forename: Entissar Sulaiman
authors.initials: ES
authors.lastname: Al Suhaibani
authors.forename: Nadeem Abbas
authors.initials: NA
authors.lastname: Kizilbash
authors.forename: Fatima
authors.initials: F
authors.lastname: Al Beladi
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D018288:Carcinoma, Small Cell / Q000473:pathology* / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D060787:Neoplasm Grading; D009361:Neoplasm Invasiveness; D011379:Prognosis; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery; D012529:Saudi Arabia; D020728:Transurethral Resection of Prostate / Q000379:methods*