title: ZMP: a master regulator of one-carbon metabolism.
abstract: In this issue, Kim et al. (2015) show that ZMP (5-aminoimidazole-4-carboxamide ribonucleotide) binds to and activates a conserved riboswitch to regulate expression of one-carbon metabolism genes.
authors.affiliation: The Lewis-Sigler Institute for Integrative Genomics and Department of Chemistry, Princeton University, Princeton, NJ 08544, USA.
authors.forename: Gregory S
authors.initials: GS
authors.lastname: Ducker
authors.affiliation: The Lewis-Sigler Institute for Integrative Genomics and Department of Chemistry, Princeton University, Princeton, NJ 08544, USA. Electronic address: joshr@genomics.princeton.edu.
authors.forename: Joshua D
authors.initials: JD
authors.lastname: Rabinowitz
mesh_terms: D000818:Animals; D011992:Endosomes / Q000201:enzymology*; D006801:Humans; D008297:Male; D000076222:Mechanistic Target of Rapamycin Complex 1; D046912:Multiprotein Complexes / Q000502:physiology*; D010588:Phagosomes / Q000201:enzymology*; D011499:Protein Processing, Post-Translational; D058570:TOR Serine-Threonine Kinases / Q000502:physiology*; D025521:Tumor Suppressor Proteins / Q000378:metabolism*
chemical_list: D046912:Multiprotein Complexes; D025521:Tumor Suppressor Proteins; C408122:UVRAG protein, human; D000076222:Mechanistic Target of Rapamycin Complex 1; D058570:TOR Serine-Threonine Kinases