title: Identification of a novel HLA-DRB1*04 null allele, HLA-DRB1*04:178N.
abstract: A single nucleotide insertion in codon 77 of HLA-DRB*04:05:01 results in a null allele, HLA-DRB1*04:178N.
authors.affiliation: Laboratory of Immunogenetics, Tzu Chi Cord Blood Bank, and Buddhist Tzu Chi Bone Marrow Donor Registry, Buddhist Tzu Chi Stem Cells Centre, Buddhist Tzu Chi General Hospital, Hualien, Taiwan; Department of Laboratory Medicine, Tzu Chi University, Hualien, Taiwan.
authors.forename: K L
authors.initials: KL
authors.lastname: Yang
authors.forename: S K
authors.initials: SK
authors.lastname: Lee
authors.forename: J H
authors.initials: JH
authors.lastname: Hung
authors.forename: P Y
authors.initials: PY
authors.lastname: Lin
mesh_terms: D000483:Alleles; D001483:Base Sequence; D018388:Codon, Terminator; D005091:Exons; D059811:HLA-DRB1 Chains / Q000145:classification / Q000235:genetics* / Q000276:immunology; D018380:Hematopoietic Stem Cell Transplantation; D006650:Histocompatibility Testing; D006801:Humans; D008969:Molecular Sequence Data; D016254:Mutagenesis, Insertional; D020033:Protein Isoforms / Q000145:classification / Q000235:genetics / Q000276:immunology; D016415:Sequence Alignment; D061349:Unrelated Donors
chemical_list: D018388:Codon, Terminator; D059811:HLA-DRB1 Chains; C527195:HLA-DRB1*04 antigen; D020033:Protein Isoforms
keywords: HLA-DRB1*04:178N; human leukocyte antigen; null allele