title: Mitochondrial biogenesis: cell-cycle-dependent investment in making mitochondria.
abstract: Mitochondria cannot be made de novo, so pre-existing mitochondria must be inherited at each cell division. A new study demonstrates cell-cycle-dependent regulation of the activity of the TOM translocase complex to induce mitochondrial biogenesis during the M phase of the cell cycle.
authors.affiliation: Department of Microbiology, Monash University, Clayton 3800, Australia.
authors.forename: Takuya
authors.initials: T
authors.lastname: Shiota
authors.affiliation: Department of Biochemistry and Molecular Biology, Monash University, Clayton 3800, Australia.
authors.forename: Ana
authors.initials: A
authors.lastname: Traven
authors.affiliation: Department of Microbiology, Monash University, Clayton 3800, Australia. Electronic address: trevor.lithgow@monash.edu.
authors.forename: Trevor
authors.initials: T
authors.lastname: Lithgow
mesh_terms: D002453:Cell Cycle; D008928:Mitochondria / Q000378:metabolism*; D033681:Mitochondrial Membrane Transport Proteins / Q000378:metabolism*; D011498:Protein Precursors / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*
chemical_list: D033681:Mitochondrial Membrane Transport Proteins; D011498:Protein Precursors; D029701:Saccharomyces cerevisiae Proteins