title: Cerebral salt wasting: a report of three cases.
abstract: Hyponatremia secondary to the Syndrome of Inappropriate Anti-Diuretic Hormone (SIADH) secretion is commonly observed in patients with various neurological disorders. Cerebral Salt Wasting (CSW) resulting in hyponatremia is also an infrequent occurrence in some patients with neurological disorders. Confusion in differentiating CSW from SIADH may arise since both results in similar electrolyte disturbances. Herein, we report three cases of CSW with intracranial afflictions. CSW was diagnosed on the basis of fractional excretion of urinary sodium and uric acid along with extremely low serum uric acid. Improvements in serum sodium levels after saline hydration and fludrocortisone administration further supported the diagnosis.
authors.affiliation: Department of Nephrology, Fatima Memorial Hospital, University of Health Sciences, Lahore.
authors.forename: Haroon
authors.initials: H
authors.lastname: Younas
authors.affiliation: Department of Nephrology, Fatima Memorial Hospital, University of Health Sciences, Lahore.
authors.forename: Omer
authors.initials: O
authors.lastname: Sabir
authors.affiliation: Department of Medicine, Fatima Memorial Hospital, University of Health Sciences, Lahore.
authors.forename: Ilyas
authors.initials: I
authors.lastname: Baig
authors.affiliation: Department of Nephrology, Fatima Memorial Hospital, University of Health Sciences, Lahore.
authors.forename: Nauman
authors.initials: N
authors.lastname: Tarif
mesh_terms: D061605:Administration, Intravenous; D000293:Adolescent; D000328:Adult; D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D006259:Craniocerebral Trauma / Q000150:complications; D017809:Fatal Outcome; D005260:Female; D005438:Fludrocortisone / Q000627:therapeutic use*; D005440:Fluid Therapy; D006406:Hematoma / Q000150:complications / Q000209:etiology; D006801:Humans; D007010:Hyponatremia / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D008297:Male; D012965:Sodium Chloride / Q000008:administration & dosage* / Q000097:blood / Q000652:urine; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D012965:Sodium Chloride; D005438:Fludrocortisone