title: [Factors associated with glycemic control in adults with type 1 diabetes mellitus on an insulin pump].
abstract: OBJECTIVE
  To explore the factors associated with glycemic control in adults with type 1 diabetes mellitus (T1D) on an insulin pump.
  
  
  METHODS
  A total of 108 patients aged over 18 years and on an insulin pump therapy for >6 months were selected from 16 centers of Guangdong Type 1 diabetes Translational Medicine Study. They were classified into two groups according to the (American Diabetes Association) ADA Hemoglobin A1c target (7.0%). Those reaching the target (n = 59) were compared with those failed (n = 49) using ANOVA and Logistic regression.
  
  
  RESULTS
  There were 75 females and 33 males with a median age of 32.0 (25.9-40.9) years and a median disease duration of 7.9(4.2-12.3) years. Logistic regression analysis revealed an odds ratio of 4.48(95%CI 1.53-13.15, P = 0.00) for total daily basal insulin dose within 0.2-0.3 units per kilogram, an OR of 1.31 (95%CI 1.05-1.63, P = 0.01) for self-monitoring of blood glucose (SMBG) and an OR of 3.43 (95%CI 1.18-10.01, P = 0.02) for males.
  
  
  CONCLUSIONS
  Higher frequencies of SMBG and appropriate basal insulin dose are essential for adult patients with T1D on an insulin pump.
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Wen
authors.initials: W
authors.lastname: Xu
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Heying
authors.initials: H
authors.lastname: Ai
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Lü
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Yanhua
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Daizhi
authors.initials: D
authors.lastname: Yang
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Shuo
authors.initials: S
authors.lastname: Lin
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Xueying
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China. Email: yanjh79@163.com.
authors.forename: Jinhua
authors.initials: J
authors.lastname: Yan
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Yao
authors.affiliation: Department of Endocrinology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Jianping
authors.initials: J
authors.lastname: Weng
mesh_terms: D000328:Adult; D001786:Blood Glucose; D015190:Blood Glucose Self-Monitoring; D003922:Diabetes Mellitus, Type 1; D005260:Female; D038321:Glycemic Index; D006801:Humans; D007328:Insulin; D007332:Insulin Infusion Systems; D016015:Logistic Models; D008297:Male; D016017:Odds Ratio
chemical_list: D001786:Blood Glucose; D007328:Insulin