title: Studies of troponin I level changes in patients with coronary artery disease after percutaneous coronary intervention.
abstract: Research has been carried out in TSMU Cardiology department of A.Aladashvili University Clinic involving 150 patients with ischemic heart disease. The changes of Tn level before and after percutaneous coronary intervention (PCI) in patients with CAD as well as its dependence on the cardiovascular events rate have been studied in previous work. In patients with normal Tn I level before and after PCI hospital cardiovascular events rate occurred to be as low as the rate of later events. Elevated level of Tn I after PCI was associated with increased rate of complications, which were mostly appeared in those patients with high level of Tn I before PCI. High level of 30-day mortality was revealed in patients with normal level of Tn I before PCI, which was elevated after procedure. The highest rate of later mortality was demonstrated in patients with high level of Tn I before PCI that was sustained after procedure. Hence, on the basis of our data we can conclude, that the Tn level before and after PCI has a prognostic significance; High level of Tn I before PCI is associated with increased hospitalization and later mortality rates. The elevation of Tn I after PCI in patients with normal initial level is more significant predictor of early (30-day) mortality compared to later (within 12 months) mortality.
authors.affiliation: Tbilisi State Medical University, A. Aladashvili University Clinic, Iinternal Medicine Department в"-1, Georgia.
authors.forename: N
authors.initials: N
authors.lastname: Emukhvari
authors.affiliation: Tbilisi State Medical University, A. Aladashvili University Clinic, Iinternal Medicine Department в"-1, Georgia.
authors.forename: E
authors.initials: E
authors.lastname: Tsetskhladze
authors.affiliation: Tbilisi State Medical University, A. Aladashvili University Clinic, Iinternal Medicine Department в"-1, Georgia.
authors.forename: Kh
authors.initials: Kh
authors.lastname: Khijakadze
authors.affiliation: Tbilisi State Medical University, A. Aladashvili University Clinic, Iinternal Medicine Department в"-1, Georgia.
authors.forename: I
authors.initials: I
authors.lastname: Mamatsashvili
authors.affiliation: Tbilisi State Medical University, A. Aladashvili University Clinic, Iinternal Medicine Department в"-1, Georgia.
authors.forename: I
authors.initials: I
authors.lastname: Khintibidze
mesh_terms: D060050:Angina, Stable / Q000097:blood* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D015415:Biomarkers / Q000097:blood; D003324:Coronary Artery Disease / Q000097:blood* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D005260:Female; D006333:Heart Failure / Q000097:blood* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention; D011379:Prognosis; D012307:Risk Factors; D016896:Treatment Outcome; D019210:Troponin I / Q000097:blood*
chemical_list: D015415:Biomarkers; D019210:Troponin I