title: Factors associated with treatment of osteoarthritis: Analysis of a COPCORD study in Nuevo León, México.
abstract: BACKGROUND
  Osteoarthritis (OA) is the most prevalent rheumatic disease in Mexico. Treatment involves pharmacological and non-pharmacological strategies.
  
  
  OBJECTIVE
  To describe the factors associated with treatment of osteoarthritis in the urban and rural population of Nuevo León.
  
  
  METHODS
  Analysis of a cross-sectional study of patients with OA from a COPCORD study database. Univariate and multivariate analyses of the variables associated with treatment of OA.
  
  
  RESULTS
  We included 696 patients with OA with an average age of 58 years (SD 14.1), 484 (69.5%) women. Pain with a visual analog scale (VAS) ≥4 was present in 507 (72.8%) patients. Functional disability was present in 133 (19%) patients and a mean HAQ of 0.37 (IQR 0.75) was found. The most frequent place of OA was knee in 356 (51.1%) patients; 259 (37%) patients already knew their diagnosis. The most employed treatments were non-steroidal anti-inflammatory drugs (289 patients, 58.5%). The variables associated with treatment were age >58 years (OR 1.3, 95% CI 1.0-1.5), female gender (OR 1.17, 95% CI 1.0-1.3), VAS pain ≥4 (OR 1.3, 95% CI 1.1-1.4), functional disability (OR 2.6, 95% CI 1.6-4.1), HAQ >0.375 (OR 1.9, 95% CI 1.5-2.4), and past diagnosis of OA (OR 5.1, 95% CI 3.3-8.0). In the multivariate analysis, VAS pain ≥4 (OR 1.9, 95% CI 1.2-2.8), kneeling disability (OR 3.15, 95% CI 1.3-7.4) and previous diagnosis of OA (OR 7.6, 95% CI 4.5-12.9) had statistical significance.
  
  
  CONCLUSIONS
  factors associated with treatment of OA are VAS pain ≥4, kneeling disability and previous diagnosis of OA.
authors.affiliation: Department Internal Medicine, Rheumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico.
authors.forename: Alexia Estefanía
authors.initials: AE
authors.lastname: Hernández-Cáceres
authors.affiliation: Department Internal Medicine, Rheumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Rodriguez-Amado
authors.affiliation: Department of Rheumatology, Hospital General de México "Dr. Eduardo Liceaga", Ciudad de México, Distrito Federal, Mexico.
authors.forename: Ingris
authors.initials: I
authors.lastname: Peláez-Ballestas
authors.affiliation: Department Internal Medicine, Rheumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico.
authors.forename: David
authors.initials: D
authors.lastname: Vega-Morales
authors.affiliation: Department Internal Medicine, Rheumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, Mexico. Electronic address: mariogarz@hotmail.com.
authors.forename: Mario Alberto
authors.initials: MA
authors.lastname: Garza-Elizondo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico; D008875:Middle Aged; D010003:Osteoarthritis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D019035:Rural Health Services / Q000706:statistics & numerical data*; D019037:Urban Health Services / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal
keywords: Epidemiology; Musculoskeletal diseases; Osteoarthritis; Risk factors; Therapeutics