title: [Impact of percutaneous coronary intervention versus medical therapy on mortality in stable coronary artery disease: a meta-analysis].
abstract: OBJECTIVE
  To compare the impacts of percutaneous coronary intervention (PCI) and medical therapy on mortality in patients with stable coronary artery disease.
  
  
  METHODS
  We searched PubMed,Embase, Cochrane central register of controlled trials, Wanfang data and CNKI to find relevant randomized controlled trials on PCI versus medical therapy for treating patients with stable coronary artery disease, which were reported before December 2013. Publications were selected according to inclusion and exclusion standard. Meta-analyses was performed with the software of STATA 12.0.
  
  
  RESULTS
  Five randomized controlled trials and 5 567 patients were enrolled for this analysis. Compared with medical therapy, PCI could not significantly decrease the long-term all-cause mortality (RR = 0.96, 95%CI 0.80-1.15), the cardiac death rate (RR = 1.02, 95%CI 0.77-1.36), the myocardial infarction rate (RR = 1.05, 95%CI 0.89-1.23), the acute coronary syndrome (RR = 0.70, 95%CI 0.27-1.82), the rate of freedom from angina (RR = 1.09, 95%CI 0.98-1.21), and the rate of stroke (RR = 1.27, 95%CI 0.75-2.15).However, the revascularization rate was significantly lower for patients in PCI group (RR = 0.60, 95%CI 0.42-0.86).
  
  
  CONCLUSIONS
  Long-term mortality is similar for patients with stable coronary artery disease underwent PCI or medical therapy.
authors.affiliation: Department of Integrated Intensive Care Unit, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
authors.forename: Youdong
authors.initials: Y
authors.lastname: Wan
authors.affiliation: Email: suntongwen@163.com.
authors.forename: Tongwen
authors.initials: T
authors.lastname: Sun
authors.forename: Ziqi
authors.initials: Z
authors.lastname: Liu
authors.forename: Shuguang
authors.initials: S
authors.lastname: Zhang
authors.forename: Rui
authors.initials: R
authors.lastname: Yao
authors.forename: Haimu
authors.initials: H
authors.lastname: Yao
authors.forename: Quancheng
authors.initials: Q
authors.lastname: Kan
mesh_terms: D000787:Angina Pectoris; D003324:Coronary Artery Disease / Q000401:mortality* / Q000628:therapy*; D003327:Coronary Disease; D006801:Humans; D009203:Myocardial Infarction; D062645:Percutaneous Coronary Intervention; D016032:Randomized Controlled Trials as Topic; D020521:Stroke