title: Psychomotor retardation in a girl with complete growth hormone deficiency.
abstract: Infants with complete growth hormone deficiency may suffer from psychomotor retardation in addition to severe growth failure. Without replacement therapy, they may have a compromised intellectual potential manifesting as learning disabilities and attention-deficit disorders in later life. In this communication, we discuss an infant who showed improvement in physical growth after growth hormone therapy but her psychomotor skills did not improve probably due to late start of treatment. There is a need to start growth hormone therapy as early as possible in infants with complete growth hormone deficiency to avoid adverse effects on psychomotor and brain development.
authors.forename: Devi
authors.initials: D
authors.lastname: Dayal
authors.forename: Prabhjot
authors.initials: P
authors.lastname: Malhi
authors.forename: Anil
authors.initials: A
authors.lastname: Kumar Bhalla
authors.forename: Naresh
authors.initials: N
authors.lastname: Sachdeva
authors.forename: Rakesh
authors.initials: R
authors.lastname: Kumar
mesh_terms: D001921:Brain / Q000187:drug effects*; D002658:Developmental Disabilities / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006130:Growth Disorders / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D013006:Growth Hormone / Q000172:deficiency*; D006801:Humans; D007223:Infant; D011597:Psychomotor Performance / Q000187:drug effects*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D013006:Growth Hormone