title: Versatile polyiodopyrazoles: synthesis and biocidal promise.
abstract: An efficient route to polyiodopyrazoles, 3,4,5-triiodopyrazole (1), 1-methyl-3,4,5-triiodopyrazole (2) and 1-diiodomethyl-3,4,5-triiodopyrazole (3), opens the door to prospective biocides. Nitration of 1 and 2 gives the previously inaccessible compounds, 3,4-dinitro-5-iodopyrazole (4), and 3,4-dinitro-5-iodo-1-methylpyrazole (5), respectively. These synthetic pathways will open many fronts for pyrazole chemistry.
authors.affiliation: Department of Chemistry, University of Idaho, Moscow, ID 83844-2343, USA. jshreeve@uidaho.edu.
authors.forename: Deepak
authors.initials: D
authors.lastname: Chand
authors.forename: Jean'ne M
authors.initials: JM
authors.lastname: Shreeve
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D008958:Models, Molecular; D008968:Molecular Conformation; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D011720:Pyrazoles; C010201:4-iodopyrazole