title: [Histological observation of preserving intercostobrachial nerve during axillary lymph node dissection for breast carcinoma].
abstract: OBJECTIVE
  To explore the reliability of preserving intercostobrachial nerve (ICBN) during axillary lymph node dissection for breast carcinoma.
  
  
  METHODS
  A total of 57 patients with breast carcinoma undergoing routine operations were analyzed. The extirpated ICBN and ambient tissues were tested by hematoxylin and eosin staining to observe the pathological changes under microscope. If there was an infiltration of carcinoma, 4 immunohistochemical markers, including human mammaglobin (hMAM), were tested in related tissue.
  
  
  RESULTS
  Among them, no microscopic infiltration of carcinoma was found in 55 cases. In 27 cases with axillary lymph node metastasis, 1 case had an infiltration of carcinoma and carcinoma cells were present in tissues around ICBN in another case. Immunohistochemistry showed that hMAM, GCDFP-15, estrogen receptor (ER) and progesterone receptor (PR) were all positive in infiltrated ICBN. And carcinoma cells in tissues around ICBN expressed ER, PR and hMAM positively and GCDFP-15 negatively.
  
  
  CONCLUSIONS
  Unless intercostobrachial nerves and enlarged lymph nodes adhere heavily, preserving ICBN is feasible for breast carcinoma surgery.
authors.affiliation: Department of Human Anatomy, Hebei United University, Tangshan 063000, China.
authors.forename: Huan
authors.initials: H
authors.lastname: Zheng
authors.forename: Chang
authors.initials: C
authors.lastname: Shi
authors.forename: Shiwei
authors.initials: S
authors.lastname: Zhang
authors.forename: Zhaopeng
authors.initials: Z
authors.lastname: Tang
authors.forename: Yuanshui
authors.initials: Y
authors.lastname: Chen
authors.forename: Mei
authors.initials: M
authors.lastname: Ding
authors.forename: Hongcheng
authors.initials: H
authors.lastname: Zhu
authors.forename: Jucai
authors.initials: J
authors.lastname: Xiang
authors.forename: Hong
authors.initials: H
authors.lastname: Sun
authors.forename: Xudong
authors.initials: X
authors.lastname: Song
authors.affiliation: Department of Surgical Oncology, Affiliated Hospital, Hebei United University, Tangshan 063000, China. Email: xwg853@163.com.
authors.forename: Weiguo
authors.initials: W
authors.lastname: Xu
mesh_terms: D001365:Axilla; D001943:Breast Neoplasms; D006801:Humans; D007150:Immunohistochemistry; D007367:Intercostal Nerves; D008197:Lymph Node Excision; D008198:Lymph Nodes; D008207:Lymphatic Metastasis; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D015203:Reproducibility of Results
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone