title: [Pregabalin can cause addiction and withdrawal symptoms].
abstract: A 38-year-old man was referred to the psychiatric department due to auditory hallucinations, suicidal ideation and a large daily intake of 8.4 g pregabalin. The Danish National Medication Register showed that the patient had bought pregabalin 21 times within the last two months, a total of 487.2 g pregabalin. Withdrawal symptoms disappeared within 48 hours, psychotic experiences and the suicidal ideations faded during the next couple of weeks. High doses of pregabalin are tolerated with surprisingly few toxicological consequences, though lethal cases have been described. Pregabalin abuse, however, can lead to dependency.
authors.affiliation: Psykiatrisk Center Hvidovre, Brøndbyøstervej 160, 2605 Brøndby. julie.nordgaard.frederiksen@regionh.dk.
authors.forename: Julie
authors.initials: J
authors.lastname: Nordgaard
authors.forename: Gesche
authors.initials: G
authors.lastname: Jürgens
mesh_terms: D000328:Adult; D014151:Anti-Anxiety Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000737:chemistry / Q000627:therapeutic use; D001007:Anxiety / Q000188:drug therapy; D006212:Hallucinations / Q000139:chemically induced / Q000188:drug therapy; D006801:Humans; D008297:Male; D000069583:Pregabalin / Q000008:administration & dosage / Q000009:adverse effects* / Q000737:chemistry / Q000627:therapeutic use; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy / Q000209:etiology*; D019966:Substance-Related Disorders / Q000188:drug therapy / Q000209:etiology; D059020:Suicidal Ideation
chemical_list: D014151:Anti-Anxiety Agents; D000069583:Pregabalin