title: [Clinical feature of chronic compressive optic neuropathy without optic atrophy].
abstract: OBJECTIVE
  To investigate the clinical feature of the chronic compressive optic neuropathy without optic atrophy.
  
  
  METHODS
  Retrospective cases series study. The clinical data of 25 patients (37 eyes) with chronic compressive optic neuropathy without optic atrophy, treated in Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, from October, 2005 to March, 2014, were collected. Those patients had been showing visual symptoms for 6 months or longer, but missed diagnosed or misdiagnosed as other eye diseases due to their normal or slightly changed fundi. The collected data including visual acuities, visual fields, neuroimaging and/or pathologic diagnosis were analyzed.
  
  
  RESULTS
  Among the 25 patients, there were 5 males and 20 females, and their ages range from 9 to 74 years [average (47.5 ± 13.4) years]. All patients suffered progressive impaired vision in single eye or both eyes, without exophthalmos or abnormal eye movements. Except one patient had a headache, other patients did not show systemic symptoms. The corrected visual acuities were between HM to 1.0, and their appearances of optic discs and colors of fundi were normal. After neuroimaging and/or pathological examination, it was proven that 14 patients suffered tuberculum sellae meningiomas, 5 patients with hypophysoma, 3 patient with optic nerve sheath meningioma in orbital apex, 1 patient with cavernous hemangioma, 1 patient with vascular malformation in orbital apex and 1 patient with optic nerve glioma. Among the 19 patients whose suffered occupied lesions of saddle area, 14 patients underwent visual field examinations, and only 4 patients showed classic visual field defects caused by optic chiasmal lesions.
  
  
  CONCLUSIONS
  Occult progressive visual loss was the most important clinical feature of the disease.
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing 100730, China. Email: jlbjlb@sina.com.
authors.forename: Libin
authors.initials: L
authors.lastname: Jiang
authors.forename: Jitong
authors.initials: J
authors.lastname: Shi
authors.forename: Wendong
authors.initials: W
authors.lastname: Liu
authors.forename: Jun
authors.initials: J
authors.lastname: Kang
authors.forename: Ningli
authors.initials: N
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002908:Chronic Disease; D003951:Diagnostic Errors; D005094:Exophthalmos; D005128:Eye Diseases / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000175:diagnosis; D008579:Meningioma / Q000150:complications / Q000175:diagnosis; D008875:Middle Aged; D009186:Myelin Sheath; D009896:Optic Atrophy; D009898:Optic Disk / Q000033:anatomy & histology; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000209:etiology*; D012189:Retrospective Studies; D014786:Vision Disorders / Q000209:etiology*; D014792:Visual Acuity; D014794:Visual Fields