title: Patient- and therapy-related factors on the wear of denture teeth--results of a clinical trial.
abstract: OBJECTIVE
  When we examined a previously published prospective multi-center clinical trial in which complete denture-wearers were followed over a period of 2 years, we found that about 30% of the variability in the clinical wear data of denture teeth was due to unknown characteristics of the subjects. In the second part of the study, we try to identify which patient- and therapy-related factors may explain some of this variability.
  
  
  METHODS
  The clinical wear data of denture teeth at different recall times (6, 12, 18, 24 months) in 89 subjects (at baseline) were correlated with the following parameters, which may all have an influence on the wear of denture teeth: age, gender, bruxism as reported by the subjects, number of prostheses used so far, time since last extraction, smoking, fit of dentures as judged by the subject and the clinician, average denture wearing time and wearing of denture during the night. To evaluate the influence of the different patient- and therapy-related variables, both a univariate analysis (one extra factor to the model) and a multivariate analysis were carried out using linear mixed models with the variable Log mean as the outcome.
  
  
  RESULTS
  None of the patient- and therapy-related parameters showed a statistically significant effect on the wear of denture teeth. There was, however, a trend for women to show less wear compared to men and a trend of decreasing wear with increasing age.
  
  
  CONCLUSIONS
  Further research is required to identify the factors which are responsible for the high variability observed between the subjects regarding clinical wear data.
authors.affiliation: R&D, Ivoclar Vivadent, Schaan, Liechtenstein. Electronic address: siegward.heintze@ivoclarvivadent.com.
authors.forename: Siegward D
authors.initials: SD
authors.lastname: Heintze
authors.affiliation: Institute for Social and Preventive Medicine, University of Lausanne, Switzerland.
authors.forename: Valentin
authors.initials: V
authors.lastname: Rousson
authors.affiliation: Department of Prosthodontics, Heidelberg University Hospital, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Stober
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019554:Dental Restoration Wear; D003824:Denture, Complete; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors
keywords: Clinical trial; Denture teeth; Patient factors; Wear