title: Risk of suicide for individuals reporting asthma and atopy in young adulthood: findings from the Glasgow Alumni study.
abstract: There is emerging evidence that asthma and atopy may be associated with a higher risk of suicide. We investigated the association of asthma and atopy with mortality from suicide (n=32) in the Glasgow Alumni cohort, adjusting for the key confounders of socioeconomic position and smoking. We found no evidence of an association in our a priori atopy phenotypes with suicide, and there were insufficient suicides in the asthma phenotypes to draw any conclusions. In additional analyses, individuals reporting both eczema-urticaria and hay fever and those with family history of atopy were at higher risk of suicide. As these were secondary analyses and based on small numbers of events we cannot rule out chance findings. The lack of evidence in our main hypothesis may be due to the small number of suicides or reported associations between asthma and atopy may be confounded.
authors.affiliation: School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK. Electronic address: Andrew.Crawford@bristol.ac.uk.
authors.forename: Andrew A
authors.initials: AA
authors.lastname: Crawford
authors.affiliation: School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.
authors.forename: Bruna
authors.initials: B
authors.lastname: Galobardes
authors.affiliation: School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.
authors.forename: Mona
authors.initials: M
authors.lastname: Jeffreys
authors.affiliation: MRC Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.
authors.forename: George Davey
authors.initials: GD
authors.lastname: Smith
authors.affiliation: School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.
authors.forename: David
authors.initials: D
authors.lastname: Gunnell
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000453:epidemiology / Q000523:psychology*; D004485:Eczema / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000453:epidemiology / Q000523:psychology*; D008297:Male; D015995:Prevalence; D006255:Rhinitis, Allergic, Seasonal / Q000453:epidemiology / Q000523:psychology*; D012306:Risk; D012907:Smoking / Q000523:psychology; D013405:Suicide / Q000523:psychology / Q000706:statistics & numerical data*; D055815:Young Adult
keywords: Asthma; Atopy; Suicide