title: [The correlation of allergic rhinitis and trace elements in Ningxia region].
abstract: OBJECTIVE
  To investigate the correlation of allergic rhinitis and trace elements and to provide a reference for clinical diagnosis, treatment and prevention of allergic rhinitis.
  
  
  METHODS
  One hundred and six patients were diagnosed as allergic rhinitis in General Hospital of Ningxia Medical University between January and December in 2010, including 48 cases of perennial allergic rhinitis and 58 cases of seasonal allergic rhinitis. In the same time, one hundred and three healthy volunteers were selected as control. Intravenous blood 3-5 ml were obtained from all subjects both in experimental group and in control group. The content of Ca, Ni, Fe, Mg, Zn, Sr, Mn, Cu, Se in serum and hair was determined by inductively coupled plasma atomic emission spectrometry (ICP-AES). The t-test (SPSS 16.0) was used to compare the results of trace elements in serum between allergic rhinitis and control group.
  
  
  RESULTS
  The testing results of trace elements in AR patients serum and normal controls serum were as follows: Cu, Ni (1 002.18 ± 104.62) µg/L, (21.58 ± 5.54) mg/L were super than control group, (832.78 ± 50.45) µg/L, (17.04 ± 4.93) mg/L (t value was 15.545, 5.154, both P < 0.05). But the content of Zn, Se (793.48 ± 46.88) µg/L, (84.25 ± 12.77) µg/L lower than control group (908.53 ± 31.26) µg/L, (98.35 ± 15.21) µg/L (t value was -24.175 and -7.797, both P < 0.05) . The testing results of trace elements in AR patients hair and normal controls hair were as follows: Cu, Ni (42.43 ± 5.03) µg/g, (31.72 ± 5.49) µg/g were super than control group, (23.00 ± 4.45) µg/g, (8.94 ± 7.53) µg/g (t value was -8.633 and 4.236, both P < 0.05). But the content of Zn, Se (92.16 ± 4.54) µg/g , (0.28 ± 0.04) µg/g lower than control group (189.09 ± 8.45) µg/g, (0.39 ± 0.06) µg/g (t value was -28.71 and -8.633, both P < 0.05).
  
  
  CONCLUSIONS
  The content of Zn, Se in AR patients serum are lower than that in control group. But the content of Cu, Ni in AR patients serum are super than that in control group. There are no significant difference of trace elements in the serum between pennial allergic rhinitis and seasonal allergic rhinitis.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China. Email: maruixia4368@sina.com.
authors.forename: Ruixia
authors.initials: R
authors.lastname: Ma
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
authors.forename: Yueling
authors.initials: Y
authors.lastname: Shen
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
authors.forename: Li
authors.initials: L
authors.lastname: Hou
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
authors.forename: Zhichao
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
authors.forename: Ningyu
authors.initials: N
authors.lastname: Feng
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Yan
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Shao
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Gao
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
authors.forename: Lingling
authors.initials: L
authors.lastname: Di
mesh_terms: D000393:Air Pollutants / Q000032:analysis*; D000397:Air Pollution / Q000706:statistics & numerical data*; D002681:China / Q000453:epidemiology; D006197:Hair; D006801:Humans; D065631:Rhinitis, Allergic / Q000453:epidemiology* / Q000378:metabolism; D012221:Rhinitis, Allergic, Perennial; D006255:Rhinitis, Allergic, Seasonal; D014131:Trace Elements / Q000032:analysis*
chemical_list: D000393:Air Pollutants; D014131:Trace Elements