title: Reliability and validity of the Korean version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire to assess Chemotherapy-induced peripheral neuropathy.
abstract: OBJECTIVE
  This study was performed to assess the reliability and validity of the Korean version of European Organization for Research and Treatment of Cancer Quality of Life Questionnaire - Chemotherapy-induced peripheral neuropathy 20 items (EORTC QLQ-CIPN20) in patients receiving neurotoxic chemotherapy.
  
  
  METHODS
  A convenience sample of 249 Korean cancer patients, previously or currently, being treated with peripheral neurotoxic chemotherapeutic agents were asked to fill in the questionnaire. Collected data were analyzed using SPSS 21.0 and AMOS 21.0. Construct validity, known-group validity, concurrent validity, and internal consistency reliability of the Korean version of the QLQ-CIPN20 were evaluated.
  
  
  RESULTS
  Factor analysis confirmed 3 dimensions of CIPN: sensory, motor, and autonomic. The factor loadings of the 20 items on the 3 subscales ranged from .38 to .85. The 3 subscale-model was validated by confirmatory factor analysis (GFI=.90, AGFI=.86, RMSR=.05, NFI=.87, and CFI=.94), and concurrent validity was demonstrated with the EORTC QLQ-C30. Furthermore, the QLQ-CIPN20 established known-group validity. The Cronbach's alpha coefficients for internal consistency of the subscales ranged from .73 to .89.
  
  
  CONCLUSIONS
  The Korean version of the EORTC QLQ-CIPN20 showed satisfactory construct, concurrent, and known-group validity, as well as internal reliability.
authors.affiliation: College of Nursing, Chonbuk National University, Jeonju, Korea.
authors.forename: Hye Young
authors.initials: HY
authors.lastname: Kim
authors.affiliation: College of Nursing, Chonbuk National University, Jeonju, Korea. jeonghee@jbnu.ac.kr.
authors.forename: Jeong Hee
authors.initials: JH
authors.lastname: Kang
authors.affiliation: Department of Surgery, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Hyun Jo
authors.initials: HJ
authors.lastname: Youn
authors.affiliation: College of Nursing, Chonnam National University, Gwangju, Korea.
authors.forename: Hyang Sook
authors.initials: HS
authors.lastname: So
authors.affiliation: Department of Hematology, Chonnam National University Hwasun Hospital, Hwasun, Korea.
authors.forename: Chi Eun
authors.initials: CE
authors.lastname: Song
authors.affiliation: Department of Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea.
authors.forename: Seo Young
authors.initials: SY
authors.lastname: Chae
authors.affiliation: Department of Surgery, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Sung Hoo
authors.initials: SH
authors.lastname: Jung
authors.affiliation: College of Nursing, Chonbuk National University, Jeonju, Korea.
authors.forename: Sung Reul
authors.initials: SR
authors.lastname: Kim
authors.affiliation: College of Nursing, Chonbuk National University, Jeonju, Korea.
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D044466:Asian People; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy; D010523:Peripheral Nervous System Diseases / Q000209:etiology*; D010865:Pilot Projects; D011788:Quality of Life; D056910:Republic of Korea; D012107:Research Design; D011795:Surveys and Questionnaires; D014175:Translating
chemical_list: D000970:Antineoplastic Agents
keywords: Chemotherapy; Peripheral neuropathies; Reliability; Validity