title: Fluorescence imaging of selenol in HepG2 cell apoptosis induced by Na2SeO3.
abstract: A novel fluorescence probe (HB) has been designed and synthesized to image selenol in living cells and in vivo for the first time, and used to investigate the Na2SeO3 anticancer mechanism in HepG2 cells.
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of Fine Chemicals, Shandong Normal University, Jinan 250014, P. R. China. tangb@sdnu.edu.cn.
authors.forename: Fanpeng
authors.initials: F
authors.lastname: Kong
authors.forename: Bo
authors.initials: B
authors.lastname: Hu
authors.forename: Yan
authors.initials: Y
authors.lastname: Gao
authors.forename: Kehua
authors.initials: K
authors.lastname: Xu
authors.forename: Xiaohong
authors.initials: X
authors.lastname: Pan
authors.forename: Fang
authors.initials: F
authors.lastname: Huang
authors.forename: Qiuling
authors.initials: Q
authors.lastname: Zheng
authors.forename: Hao
authors.initials: H
authors.lastname: Chen
authors.forename: Bo
authors.initials: B
authors.lastname: Tang
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D017209:Apoptosis; D005456:Fluorescent Dyes / Q000494:pharmacology*; D056945:Hep G2 Cells; D006801:Humans; D007211:Indoles / Q000494:pharmacology*; D061848:Optical Imaging; D016566:Organoselenium Compounds / Q000494:pharmacology*; D018036:Selenium Compounds / Q000378:metabolism*; D018038:Sodium Selenite / Q000494:pharmacology*
chemical_list: C000602299:2-(4-(2-(benzoselenadiazol-5-yl)vinyl)styryl)-1-ethyl-3,3-dimethylindolium; D000970:Antineoplastic Agents; D005456:Fluorescent Dyes; D007211:Indoles; D016566:Organoselenium Compounds; D018036:Selenium Compounds; C442270:selenol; D018038:Sodium Selenite