title: [Sensitization to Blomia tropicalis among asthmatic patients in Yaoundé, Cameroon].
abstract: BACKGROUND
  The aim of this study was to determine the prevalence and investigate associated factors for Blomia tropicalis (BT) sensitization in adolescent and adult patients with asthma in Yaoundé (Cameroon).
  
  
  METHODS
  We performed a cross-sectional study of 18 months duration (January 2012 to June 2013). All asthmatic patients who were seen for a consultation during the study period and who had a skin prick testing for perennial aeroallergens were included in the study.
  
  
  RESULTS
  Two hundred and one asthmatic patients (132 female patients, 65.7%) with median age (1st-3rd quartiles) of 35 (20-51.5) years were included in the study. Ninety-six (47.8%) patients had positive skin tests to BT. BT sensitization was associated with sensitization to two other dust mites (Dermatophagoides pteronyssinus [DP] and Dermatophagoides farinae [DF]) in 75 (86.2%) patients. The only clinical factor associated with BT sensitization was the presence of persistent rhinitis (odds ratio [confidence interval 95%]: 2.06 [1.12-3.81]). The independent allergenic factors associated with BT sensitization were sensitization to DP (3.49 [CI 95%: 1.49-8.19]), to DF (4.88 [CI 95%: 2.10-11.36]) and to German cockroach (4.16 [CI 95%: 1.72-10.09]).
  
  
  CONCLUSIONS
  Blomia tropicalis sensitization is common in asthmatic patients in Yaoundé. It occurs most often in the context of sensitization to multiple aeroallergens, particularly with sensitization to other dust mites and German cockroach.
authors.affiliation: Faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Service de pneumologie, hôpital Jamot, BP 4021, Yaoundé, Cameroun. Electronic address: pefura2002@yahoo.fr.
authors.forename: E W
authors.initials: EW
authors.lastname: Pefura-Yone
authors.affiliation: Faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Service de pneumologie, hôpital Jamot, BP 4021, Yaoundé, Cameroun.
authors.forename: E
authors.initials: E
authors.lastname: Afane-Ze
authors.affiliation: Faculté de médecine et des sciences biomédicales, université de Yaoundé I, Yaoundé, Cameroun; Service de pneumologie, hôpital Jamot, BP 4021, Yaoundé, Cameroun; Faculty of health sciences, university of Bamenda, Bamenda, Cameroun.
authors.forename: C
authors.initials: C
authors.lastname: Kuaban
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D039741:Antigens, Dermatophagoides / Q000276:immunology; D001249:Asthma / Q000453:epidemiology*; D002163:Cameroon / Q000453:epidemiology; D002648:Child; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003876:Dermatitis, Atopic / Q000453:epidemiology; D040001:Dermatophagoides farinae / Q000276:immunology; D040002:Dermatophagoides pteronyssinus / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008925:Mites / Q000276:immunology*; D015995:Prevalence; D012221:Rhinitis, Allergic, Perennial / Q000453:epidemiology*; D012882:Skin Tests; D012907:Smoking / Q000453:epidemiology; D055815:Young Adult
chemical_list: D039741:Antigens, Dermatophagoides
keywords: Allergies; Allergy; Asthma; Asthme; Blomia tropicalis; Multiple sensitization; Polysensibilisation; Rhinite; Rhinitis