title: [Colorectal cancer incidence, mortality and survival in Cali, Colombia, 1962-2012].
abstract: OBJECTIVE
  To study the colorectal cancer (CRC) behavior in Cali, Colombia, during the 1963-2012 period using data from the Population-based Cancer Registry of Cali and the Municipal Health Secretariat of Cali.
  
  
  METHODS
  An ecological time series analysis to study the CRC incidence (1962-2007) and mortality (1984-2012) rate trends; and a survival analysis of CRC cases registered in Cali between 1995 and 2004 were conducted. The age-standardized temporal trend of incidence (I-ASR) and mortality (M-ASR) rates were studied using an annual percent change (APC). The 5-year relative survival was estimated and a multivariate analysis was performed using the Cox proportional hazard regression model.
  
  
  RESULTS
  During the 1962-2007 period, CRC TTIR increased in men and women living in Cali [APC= 2.6 (95% CI 2.2-3.0) and APC= 2.2% (95% CI 1.8-2.7), respectively]. In the 1984-2012 period, the TTMR remained stable in women but increased in men in all age groups [APC= 1.8 (95% CI 0.8-2.8)]. The 5-year relative survival was independent of sex and increased from 29.7% in 1995-1999 to 39.8% in 2000-2004. The risk of dying from CRC was higher in people of lower socio-economic status (SES) vs higher SES [HR= 2.1 (95% CI: 1.7-2.6)], among people older than 70 years of age vs younger than 50 years [HR= 2.4 (95% CI: 1.9-2.9)], and for the 1995-1999 period vs 2000-2004 period [HR= 1.5 (95% CI 1.3-1.7)].
  
  
  CONCLUSIONS
  CRC is beginning to take a prominent place among the most important cancers in Cali, Colombia.
authors.affiliation: Departamento de Patología, Facultad de Salud, Universidad del Valle, Cali, Valle del Cauca, Colombia.
authors.forename: Cortés
authors.initials: C
authors.lastname: Armando
authors.affiliation: Registro Poblacional de Cáncer de Cali, Facultad de Salud, Universidad del Valle, Cali, Valle del Cauca, Colombia.
authors.forename: Luis Eduardo
authors.initials: LE
authors.lastname: Bravo
authors.affiliation: Registro Poblacional de Cáncer de Cali, Facultad de Salud, Universidad del Valle, Cali, Valle del Cauca, Colombia.
authors.forename: Pat
authors.initials: P
authors.lastname: Clín
authors.affiliation: Registro Poblacional de Cáncer de Cali, Facultad de Salud, Universidad del Valle, Cali, Valle del Cauca, Colombia.
authors.forename: Luz Stella
authors.initials: LS
authors.lastname: García
authors.affiliation: Registro Poblacional de Cáncer de Cali, Facultad de Salud, Universidad del Valle, Cali, Valle del Cauca, Colombia.
authors.forename: Paola
authors.initials: P
authors.lastname: Collazos
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003105:Colombia / Q000453:epidemiology; D015179:Colorectal Neoplasms / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009017:Morbidity / Q000639:trends; D009026:Mortality / Q000639:trends; D016016:Proportional Hazards Models; D012042:Registries; D012959:Socioeconomic Factors; D016019:Survival Analysis