title: Preparation of molecule-responsive microsized hydrogels via photopolymerization for smart microchannel microvalves.
abstract: Microdevices designed for practical environmental pollution monitoring need to detect specific pollutants such as dioxins. Bisphenol A (BPA) has been widely used as a monomer for the synthesis of polycarbonate and epoxy resins. However, the recent discovery of its high potential ability to disrupt human endocrine systems has made the development of smart systems and microdevices for its detection and removal necessary. Molecule-responsive microsized hydrogels with β-cycrodextrin (β-CD) as ligands are prepared by photopolymerization using a fluorescence microscope. The molecule-responsive micro-hydrogels show ultra-quick shrinkage in response to target BPA. Furthermore, the flow rate of a microchannel is autonomously regulated by the molecule-responsive shrinking of their hydrogels as smart microvalves.
authors.affiliation: Department of Chemistry and Materials Engineering, Kansai University, 3-3-35, Yamate-cho, Suita, Osaka, 564-8680, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Shiraki
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tsuruta
authors.forename: Junpei
authors.initials: J
authors.lastname: Morimoto
authors.forename: Chihiro
authors.initials: C
authors.lastname: Ohba
authors.forename: Akifumi
authors.initials: A
authors.lastname: Kawamura
authors.forename: Ryo
authors.initials: R
authors.lastname: Yoshida
authors.forename: Ryuji
authors.initials: R
authors.lastname: Kawano
authors.forename: Tadashi
authors.initials: T
authors.lastname: Uragami
authors.forename: Takashi
authors.initials: T
authors.lastname: Miyata
mesh_terms: D001559:Benzhydryl Compounds / Q000737:chemistry; D020100:Hydrogels / Q000737:chemistry*; D008027:Light; D054802:Molecular Imprinting; D010636:Phenols / Q000737:chemistry; D058105:Polymerization / Q000528:radiation effects; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D020100:Hydrogels; D010636:Phenols; D011108:Polymers; D047392:beta-Cyclodextrins; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: dynamic cross-link; microchannels; microfluidics; molecular recognition; stimuli-responsive hydrogels