title: Prevalence of thalassaemia, iron-deficiency anaemia and glucose-6-phosphate dehydrogenase deficiency among Arab migrating nomad children, southern Islamic Republic of Iran.
abstract: This study investigated the prevalence of iron-deficiency anaemia, glucose-6-phosphate dehydrogenase (G6PD) deficiency and β-thalassaemia trait among Arab migrating nomad children in southern Islamic Republic of Iran. Blood samples were analysed from 134 schoolchildren aged < 18 years (51 males, 83 females). Low serum ferritin (< 12 ng/dL) was present in 17.9% of children (21.7% in females and 11.8% in males). Low haemoglobin (Hb) correlated significantly with a low serum ferritin. Only 1 child had G6PD deficiency. A total of 9.7% of children had HbA2 ≥ 3.5 g/dL, indicating β-thalassaemia trait (10.8% in females and 7.8% in males). Mean serum iron, serum ferritin and total iron binding capacity were similar in males and females. Serum ferritin index was as accurate as Hb index in the diagnosis of iron-deficiency anaemia. A high prevalence of β-thalassaemia trait was the major potential risk factor in this population.
authors.affiliation: Haematology Research Centre, Nemazee Hospital, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
authors.forename: M
authors.initials: M
authors.lastname: Pasalar
authors.affiliation: Stem Cell and Transgenic Technology Research Centre, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
authors.forename: D
authors.initials: D
authors.lastname: Mehrabani
authors.affiliation: Haematology Research Centre, Nemazee Hospital, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
authors.forename: A
authors.initials: A
authors.lastname: Afrasiabi
authors.affiliation: Haematology Research Centre, Nemazee Hospital, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
authors.forename: Z
authors.initials: Z
authors.lastname: Mehravar
authors.affiliation: Stem Cell and Transgenic Technology Research Centre, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
authors.forename: I
authors.initials: I
authors.lastname: Reyhani
authors.affiliation: Haematology Research Centre, Nemazee Hospital, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
authors.forename: R
authors.initials: R
authors.lastname: Hamidi
authors.affiliation: Haematology Research Centre, Nemazee Hospital, Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
authors.forename: M
authors.initials: M
authors.lastname: Karimi
mesh_terms: D000293:Adolescent; D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000208:ethnology* / Q000209:etiology; D000855:Anorexia / Q000150:complications; D018912:Arabs / Q000706:statistics & numerical data; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D005293:Ferritins / Q000097:blood; D020022:Genetic Predisposition to Disease; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood / Q000208:ethnology* / Q000209:etiology; D006443:Hemoglobin A2 / Q000032:analysis; D006801:Humans; D007492:Iran / Q000453:epidemiology; D007501:Iron / Q000097:blood; D008297:Male; D010842:Pica / Q000150:complications; D015995:Prevalence; D012307:Risk Factors; D014171:Transients and Migrants / Q000706:statistics & numerical data*; D014881:Water Supply / Q000592:standards; D017086:beta-Thalassemia / Q000097:blood / Q000208:ethnology* / Q000209:etiology
chemical_list: D005293:Ferritins; D006443:Hemoglobin A2; D007501:Iron