title: Reversible Cerebral Vasoconstriction Syndrome, Part 2: Diagnostic Work-Up, Imaging Evaluation, and Differential Diagnosis.
abstract: The diagnostic evaluation of a patient with reversible cerebral vasoconstriction syndrome integrates clinical, laboratory, and radiologic findings. Imaging plays an important role by confirming the presence of cerebral vasoconstriction; monitoring potential complications such as ischemic stroke; and suggesting alternative diagnoses, including CNS vasculitis and aneurysmal subarachnoid hemorrhage. Noninvasive vascular imaging, including transcranial Doppler sonography and MR angiography, has played an increasingly important role in this regard, though conventional angiography remains the criterion standard for the evaluation of cerebral artery vasoconstriction. Newer imaging techniques, including high-resolution vessel wall imaging, may help in the future to better discriminate reversible cerebral vasoconstriction syndrome from primary angiitis of the CNS, an important clinical distinction.
authors.affiliation: From the Department of Diagnostic Radiology (T.R.M., R.S., D.G.), Section of Neuroradiology, University of Maryland Medical Center, Baltimore, Maryland.
authors.forename: T R
authors.initials: TR
authors.lastname: Miller
authors.affiliation: From the Department of Diagnostic Radiology (T.R.M., R.S., D.G.), Section of Neuroradiology, University of Maryland Medical Center, Baltimore, Maryland.
authors.forename: R
authors.initials: R
authors.lastname: Shivashankar
authors.affiliation: Department of Diagnostic Radiology (M.M.-B.), Section of Neuroradiology, University of Washington, Seattle, Washington.
authors.forename: M
authors.initials: M
authors.lastname: Mossa-Basha
authors.affiliation: From the Department of Diagnostic Radiology (T.R.M., R.S., D.G.), Section of Neuroradiology, University of Maryland Medical Center, Baltimore, Maryland Dgandhi@umm.edu.
authors.forename: D
authors.initials: D
authors.lastname: Gandhi
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D059906:Neuroimaging / Q000379:methods*; D020301:Vasospasm, Intracranial / Q000175:diagnosis*