title: The H3Africa policy framework: negotiating fairness in genomics.
abstract: Human Heredity and Health in Africa (H3Africa) research seeks to promote fair collaboration between scientists in Africa and those from elsewhere. Here, we outline how concerns over inequality and exploitation led to a policy framework that places a firm focus on African leadership and capacity building as guiding principles for African genomics research.
authors.affiliation: Department of Medicine, University of Cape Town, UCT Centre for Clinical Research, Old Main Building, Groote Schuur Hospital, Observatory, Cape Town 7925, South Africa. Electronic address: Jantina.devries@uct.ac.za.
authors.forename: Jantina
authors.initials: J
authors.lastname: de Vries
authors.affiliation: Navrongo Health Research Centre, Ghana Health Service, PO Box 114, Navrongo, Ghana.
authors.forename: Paulina
authors.initials: P
authors.lastname: Tindana
authors.affiliation: Wellcome Trust, Gibbs Building, London, NW1 2BE, UK.
authors.forename: Katherine
authors.initials: K
authors.lastname: Littler
authors.affiliation: Division of Human Genetics, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand and National Health Laboratory Service, PO Box 1038, Johannesburg 2000, South Africa.
authors.forename: Michèle
authors.initials: M
authors.lastname: Ramsay
authors.affiliation: Sydney Brenner Institute for Molecular Bioscience, University of the Witwatersrand, Johannesburg, Parktown 2193, South Africa.
authors.forename: Charles
authors.initials: C
authors.lastname: Rotimi
authors.affiliation: Center for Research on Genomics and Global Health, MSC 5635, Bethesda, MD 20892-5635, USA.
authors.forename: Akin
authors.initials: A
authors.lastname: Abayomi
authors.affiliation: NSB-H3A Biobank, National Health Laboratory Services of South Africa, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, Cape Town 7505, South Africa.
authors.forename: Nicola
authors.initials: N
authors.lastname: Mulder
authors.affiliation: Institute of Infectious Disease and Molecular Medicine, UCT Faculty of Health Sciences, Observatory 7925, South Africa.
authors.forename: Bongani M
authors.initials: BM
authors.lastname: Mayosi
mesh_terms: D000349:Africa; D032984:Ethics, Research; D023281:Genomics / Q000941:ethics* / Q000331:legislation & jurisprudence; D006801:Humans; D017008:Negotiating; D012959:Socioeconomic Factors
keywords: Africa; H3Africa; ethics; fairness; genomics