title: Non-Hodgkin lymphoma dominated by multiple organ extranodal disease revealed on FDG PET/CT.
abstract: The definition of primary extranodal lymphoma is rather controversial and often complicated by the variety of lymphoma types. Here we describe FDG PET/CT findings in 3 pediatric patients with diffuse large B-cell non-Hodgkin lymphomas dominated by extranodal lesions involving multiple organs. Lymphomas arising primarily in extranodal sites can present significant diagnostic challenges due to their morphological diversity and lack of uniformity in histopathological classification.
authors.affiliation: From the *Department of Nuclear Medicine, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People's Republic of China; and †Department of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
authors.forename: Xia
authors.initials: X
authors.lastname: Bai
authors.forename: Ion
authors.initials: I
authors.lastname: Codreanu
authors.forename: Summer L
authors.initials: SL
authors.lastname: Kaplan
authors.forename: Sabah
authors.initials: S
authors.lastname: Servaes
authors.forename: Hongming
authors.initials: H
authors.lastname: Zhuang
mesh_terms: D000293:Adolescent; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000000981:diagnostic imaging* / Q000473:pathology; D064847:Multimodal Imaging; D009362:Neoplasm Metastasis; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18