title: Dental anomalies and dental age assessment in treated children with acute lymphoblastic leukemia.
abstract: BACKGROUND
  This cross sectional study was performed to evaluate dental ages and incidence of dental anomalies in children treated for acute lymphoblastic leukemia (ALL).
  
  
  METHODS
  A total of 25 ALL patient who passed at least 2 years of chemotherapy and 25 healthy sex and age matched children were evaluated. Dental age as well as dental anomalies in shape, size, number, and structure was recorded based on their panoramic radiographies which were taken for dental purposes.
  
  
  RESULTS
  The number of dental anomalies significantly increased in ALL treated children. Seven ALL cases (28%) in compression to only one (4%) in control group had at least one dental anomaly. However, there was neither statistically significant differences between the mean of dental (p=0.32) and chronologic age (p=0.12) in both groups, nor between dental age of cases and control group (p=0.62).The age at the onset of treatment as well as treatment durations has not affected dental age and the incidence of dental anomalies significantly (p<0.05).
  
  
  CONCLUSIONS
  Chemotherapy in children results in emergence of dental anomaly. Dental age, maturity, and development process however seems to be independent from chemotherapy.
authors.affiliation: Department of Oral and Maxillofacial Radiology, Shiraz University of Medial Science, Shiraz, Iran.
authors.forename: L
authors.initials: L
authors.lastname: Khojastepour
authors.affiliation: Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: S
authors.initials: S
authors.lastname: Zareifar
authors.affiliation: Department of Oral and Maxillofacial Radiology, Shiraz University of Medial Science, Shiraz, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Ebrahimi
keywords: Acute Lymphoblastic Leukemia; Chemotherapy.; Dental age; Dental anomalies