title: [Clinical analysis of 53 cases of retroperitoneal schwannoma].
abstract: OBJECTIVE
  To explore the clinical characteristics, diagnosis and treatment regimens for retroperitoneal schwannoma.
  
  
  METHODS
  Clinicopathological data of 53 retroperitoneal schwannoma patients treated from January 1999 to April 2013 in our hospital were collected and analyzed using SPSS 13.0 statistical software.
  
  
  RESULTS
  Symptoms of the retroperitoneal schwannoma were vague and nonspecific. 12 patients had interrupted abdominal pain, 9 patients had abdominal discomfort, and only 6 patients presented with abdominal mass while 24 patients were detected by health checkup. There were some characteristics but not specific findings in imaging examination such as CT, ultrasonography and MRI, so preoperative diagnosis rate was low with only 9 patients diagnosed as retroperitoneal schwannoma and 21 patients diagnosed as neurogenic tumor. S-100 immunohistochemisty was very important in pathological diagnosis, and the patients with benign retroperitoneal schwannoma got 100% tumor specific 5-year survival after complete excision while the 5-year survival of malignant retroperitoneal schwannoma was only 50.0%.
  
  
  CONCLUSIONS
  Retroperitoneal schwannoma is a rare disease. Most of them are benign tumors, and complete surgical excision is the effective treatment.
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
authors.forename: Haitao
authors.initials: H
authors.lastname: Zhou
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China. Email: pumc_rodman@hotmail.com.
authors.forename: Zhixiang
authors.initials: Z
authors.lastname: Zhou
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
authors.forename: Jianwei
authors.initials: J
authors.lastname: Liang
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
authors.forename: Xingmao
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
authors.forename: Junjie
authors.initials: J
authors.lastname: Hu
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Zhao
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Fang
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Huang
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Abdominal Surgery, Cancer Hospital (Institute), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
authors.forename: Weigen
authors.initials: W
authors.lastname: Zeng
mesh_terms: D015746:Abdominal Pain; D003952:Diagnostic Imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D009442:Neurilemmoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D010808:Physical Examination; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D012187:Retroperitoneal Space; D016896:Treatment Outcome