title: [Development and optimization of diagnostically informative boichemical and coagulative correlators in various atherosclerotic lesions of carotid arteries].
abstract: Diagnostically informative biochemical and coagulative correlators in various atherosclerotic lesions of carotid arteries are developed. It has been established positive correlation of the degree of stenosis and intima-media thickness of carotid arteries with the following biochemical parameters: total cholesterol, LDL cholesterol, Apo-B, Lp(a), triglycerides, hs-C-reactive protein(CRP), interleukines (IL-1ß and IL-6), fibrinogen, D-dimers. Negative correlation was stated with respect to HDL cholesterol, Apo-A-1, protein C. The established correlators of carotid intima-medial layer and the studied laboratory indices favour their inclusion into carotid atherosclerosis monitoring.
authors.affiliation: Research Institute of Clinical Medicine, Tbilisi, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Akhvlediani
authors.affiliation: Research Institute of Clinical Medicine, Tbilisi, Georgia.
authors.forename: E
authors.initials: E
authors.lastname: Vorobiova
authors.affiliation: Research Institute of Clinical Medicine, Tbilisi, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Emukhvari
authors.affiliation: Research Institute of Clinical Medicine, Tbilisi, Georgia.
authors.forename: D
authors.initials: D
authors.lastname: Gachechiladze
mesh_terms: D050197:Atherosclerosis / Q000097:blood* / Q000473:pathology; D002097:C-Reactive Protein / Q000378:metabolism; D002339:Carotid Arteries / Q000473:pathology*; D059168:Carotid Intima-Media Thickness; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000097:blood* / Q000473:pathology; D015850:Interleukin-6 / Q000097:blood; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015850:Interleukin-6; D014280:Triglycerides; D005340:Fibrinogen; D002097:C-Reactive Protein