title: DRESS syndrome as a complication of treatment of hepatitis C virus-associated post-inflammatory liver cirrhosis with peginterferon α2a and ribavirin.
abstract: Various skin and systemic symptoms may develop as a complication of treatment with different medications and medicinal substances. One of them is a relatively rare drug reaction with eosinophilia and systemic symptoms, referred to as DRESS syndrome. The morphology of skin lesions and the patient's general health can differ; the management involves withdrawal of drugs suspected of triggering DRESS syndrome, and administration of local and systemic glucocorticosteroids. In this paper we present a case of a patient with HCV associated chronic hepatitis, treated with peginterferon α2a (PEG-IFN-α2a) and ribavirin, who developed skin lesions and systemic symptoms typical of DRESS syndrome.
authors.affiliation: First Department of Infectious Disease, J. Gromkowski Specialist Regional Hospital, Wroclaw, Poland. Head of the Department: Prof. Krzysztof Simon MD, PhD.
authors.forename: Justyna
authors.initials: J
authors.lastname: Janocha-Litwin
authors.affiliation: First Department of Infectious Disease, J. Gromkowski Specialist Regional Hospital, Wroclaw, Poland. Head of the Department: Prof. Krzysztof Simon MD, PhD.
authors.forename: Monika
authors.initials: M
authors.lastname: Pazgan-Simon
authors.affiliation: First Department of Infectious Disease, J. Gromkowski Specialist Regional Hospital, Wroclaw, Poland. Head of the Department: Prof. Krzysztof Simon MD, PhD ; Department of Infectious Diseases and Hepatology, Faculty of Medicine and Dentistry, Wroclaw Medical University, Wroclaw, Poland. Head of the Department: Prof. Krzysztof Simon MD, PhD.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Simon
keywords: DRESS syndrome; hepatitis C; interferon α; ribavirin