title: Atypical carpal tunnel syndrome in a holt oram patient: a case report and literature review.
abstract: We present a case report of a patient diagnosed with Holt-Oram syndrome (HOS) presenting with clinical and electrophysiologically confirmed carpal tunnel syndrome. Pre-operative Magnetic resonance imaging revealed an abnormal course of the median nerve; as such an atypical incision and approach were carried out to decompress the nerve to excellent post operative clinical effect. To our knowledge this is the first description of abnormal nervous course in a patient with HOS leading to peripheral entrapment. A literature surrounding the important aspects of HOS to the orthopaedic surgeon is presented concomitantly.
authors.affiliation: Department of Trauma and Orthopaedics, Royal Blackburn Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn, Lancashire, BB2 3HH, UK.
authors.forename: James
authors.initials: J
authors.lastname: Mace
authors.affiliation: Department of Trauma and Orthopaedics, Royal Blackburn Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn, Lancashire, BB2 3HH, UK.
authors.forename: Srikanth
authors.initials: S
authors.lastname: Reddy
authors.affiliation: Department of Trauma and Orthopaedics, Royal Blackburn Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn, Lancashire, BB2 3HH, UK.
authors.forename: Randeep
authors.initials: R
authors.lastname: Mohil
keywords: Carpal tunnel syndrome; congenital hand deformity; holt oram syndrome; median nerve variation; radial deficiency; thumb hypoplasia.