title: Insomnia and self-reported infections in cancer patients: An 18-month longitudinal study.
abstract: OBJECTIVE
  This study, conducted in cancer patients, aimed to evaluate longitudinally whether the presence of insomnia is associated with the occurrence of self-reported infections.
  
  
  METHODS
  Patients scheduled to receive a curative surgery for a first diagnosis of nonmetastatic cancer were solicited on the day of their preoperative visit. In total, 962 cancer patients completed the Insomnia Interview Schedule and a clinical interview to assess infectious symptoms at 6 time points: at the perioperative phase (baseline), as well as 2, 6, 10, 14, and 18 months later. At each assessment, patients were categorized into the following 3 groups: insomnia syndrome (SYN), insomnia symptoms (SX), and good sleepers (GS).
  
  
  RESULTS
  The analyses revealed that SYN patients at 1 time point were at a significantly higher risk of reporting at least 1 infectious episode at the subsequent assessment (OR = 1.31, p = .04), whereas SX patients were at a marginally significant higher risk of reporting such episodes (OR = 1.19, p = .08), as compared with GS.
  
  
  CONCLUSIONS
  Although these results need replication and the causality needs to be established, they suggest that insomnia may potentiate the risk of experiencing infections during the cancer care trajectory. (PsycINFO Database Record
authors.affiliation: School of Psychology, Université Laval.
authors.forename: Sophie
authors.initials: S
authors.lastname: Ruel
authors.affiliation: School of Psychology, Université Laval.
authors.forename: Josée
authors.initials: J
authors.lastname: Savard
authors.affiliation: School of Psychology, Université Laval.
authors.forename: Hans
authors.initials: H
authors.lastname: Ivers
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007239:Infections / Q000209:etiology*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D011598:Psychoneuroimmunology / Q000379:methods*; D057566:Self Report; D007319:Sleep Initiation and Maintenance Disorders / Q000209:etiology*