title: Adult neurogenesis in humans- common and unique traits in mammals.
abstract: New neurons are continuously generated in specific regions in the adult brain. Studies in rodents have demonstrated that adult-born neurons have specific functional features and mediate neural plasticity. Data on the extent and dynamics of adult neurogenesis in adult humans are starting to emerge, and there are clear similarities and differences compared to other mammals. Why do these differences arise? And what do they mean?
authors.affiliation: Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
authors.forename: Aurélie
authors.initials: A
authors.lastname: Ernst
authors.affiliation: Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden.
authors.forename: Jonas
authors.initials: J
authors.lastname: Frisén
mesh_terms: D000328:Adult; D000818:Animals; D005075:Biological Evolution; D003342:Corpus Striatum / Q000502:physiology; D006624:Hippocampus / Q000502:physiology; D006801:Humans; D020547:Lateral Ventricles / Q000502:physiology; D008959:Models, Neurological; D019579:Neocortex / Q000502:physiology; D055495:Neurogenesis; D009473:Neuronal Plasticity; D009830:Olfactory Bulb / Q000502:physiology; D009928:Organ Specificity; D059467:Transcriptome