title: Two-channel Near-infrared Spectroscopic Analysis of Association of Paranoia Symptoms with Prefrontal Activation.
abstract: OBJECTIVE
  The relationship between paranoia symptoms and underlying prefrontal cortex mechanisms among healthy subjects was analyzed using near-infrared spectroscopy.
  
  
  METHODS
  Seventy-eight healthy subjects were assessed for paranoia symptoms using the Japanese version of the Paranoia Checklist. Changes in hemoglobin concentrations were assessed using 2-channel near-infrared spectroscopy on the surface of the prefrontal cortex while subjects performed a verbal fluency test.
  
  
  RESULTS
  Changes in the concentration of oxygenated hemoglobin in the prefrontal cortex during a verbal fluency test did not correlate with the Japanese version of the Paranoia Checklist.
  
  
  CONCLUSIONS
  Our findings show that the symptoms of paranoia do not negatively affect the prefrontal cortex function among healthy subjects.
authors.affiliation: Department of Occupational Therapy, School of Health Science and Social Welfare, Kibi International University, Okayama, Japan.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Hirao
keywords: Near-infrared spectroscopy; Paranoia disorders; Prefrontal cortex