title: Higher total cholesterol level is associated with suicidal ideation in first-episode schizophrenia females.
abstract: There are inconsistent reports showing that the relationship between total cholesterol (TC) level and suicidality might be gender-specific. We compared 30 first-episode schizophrenia (FES) patients reporting suicidal ideation based on the Operational Criteria for Psychotic Illness (OPCRIT) checklist with 70 FES patients, who have never experienced suicidal ideation. After controlling for potential confounders, higher TC was associated with suicidal ideation only in FES females. Future studies should disentangle biological underpinnings of this gender-specific association.
authors.affiliation: Department of Psychiatry, Wroclaw Medical University, 10 Pasteur Street, 50-367 Wroclaw, Poland; Department of Genetics, Wroclaw Medical University, 1 Marcinkowski Street, 50-368 Wroclaw, Poland. Electronic address: mblazej@interia.eu.
authors.forename: Błażej
authors.initials: B
authors.lastname: Misiak
authors.affiliation: Department of Psychiatry, Wroclaw Medical University, 10 Pasteur Street, 50-367 Wroclaw, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Kiejna
authors.affiliation: Department of Psychiatry, Wroclaw Medical University, 10 Pasteur Street, 50-367 Wroclaw, Poland.
authors.forename: Dorota
authors.initials: D
authors.lastname: Frydecka
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood*; D002784:Cholesterol / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012559:Schizophrenia / Q000150:complications / Q000453:epidemiology / Q000378:metabolism*; D059020:Suicidal Ideation; D013405:Suicide; D014280:Triglycerides / Q000097:blood
chemical_list: D015415:Biomarkers; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol
keywords: Gender; Lipid levels; Schizophrenia