title: Regioselective oxidative trifluoromethylation of imidazoheterocycles via C(sp2)-H bond functionalization.
abstract: Catalytic oxidative trifluoromethylation of imidazopyridines has been carried out at room temperature through the functionalization of the sp(2) C-H bond employing Langlois reagent under ambient air. A library of 3-(trifluoromethyl)imidazo[1,2-a]pyridines with broad functionalities have been synthesized regioselectively. This methodology is also applicable to imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole.
authors.affiliation: Department of Chemistry, Visva-Bharati (A Central University) , Santiniketan 731235, India.
authors.forename: Kamarul
authors.initials: K
authors.lastname: Monir
authors.forename: Avik Kumar
authors.initials: AK
authors.lastname: Bagdi
authors.forename: Monoranjan
authors.initials: M
authors.lastname: Ghosh
authors.forename: Alakananda
authors.initials: A
authors.lastname: Hajra
mesh_terms: D002384:Catalysis; D006860:Hydrogen Bonding; D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D008745:Methylation; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D007093:Imidazoles; D011725:Pyridines; D013844:Thiazoles; C000600230:benzo(d)imidazo(2,1-b)thiazole; C000600229:imidazo(2,1-b)thiazole