title: Clinical effects of a hypercaloric and hyperproteic oral suplemment enhanced with W3 fatty acids and dietary fiber in postsurgical ambulatory head and neck cancer patients.
abstract: BACKGROUND
  Patients with head and neck cancer undergoing surgery have a high risk of nutritional complications.
  
  
  OBJECTIVE
  The aim of our study was to investigate the influence of a hypercaloric and hyperproteic oral supplement enriched with w3 FATTY ACIDS and fiber in clinical parameters in head and neck tumor postsurgical ambulatory patients with or without radiotherapy.
  
  
  METHODS
  A population of 37 ambulatory postsurgical patients with oral and laryngeal cancer was enrolled. At Hospital discharge postsurgical head and neck cancer patients were asked to consume two units per day of a hypercaloric and hyperproteic oral supplement for a twelve week period.
  
  
  RESULTS
  The mean age was 63.8+/-7.1 years (16 female/ 21 males). Duration of supplementation was 98.1±19.1 days. A significant increase of albumin and transferrin levels was observed, in total group and in patients undergoing radiotherapy and without it. No differences were detected in weight and other anthropometric parameters in total group and in patients with radiotherapy during the protocol. Nevertheless, patients without radiotherapy showed a significant improvement of BMI; weight, fat free mass and fat mass.
  
  
  CONCLUSIONS
  An omega 3 and fiber enriched formula improved seric protein levels in ambulatory postoperative head and neck cancer patients. Improvement of weight, fat mass and fat free mass was observed in patients whom not received radiotherapy during the follow up.
authors.affiliation: Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Dept Endocrinology and Nutrition, Hospital Clínico Universitario, University of Valladolid, Valladolid. Spain.. redactor04@nutricionhospitalaria.com.
authors.forename: D A
authors.initials: DA
authors.lastname: de Luis
authors.affiliation: Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Dept Endocrinology and Nutrition, Hospital Clínico Universitario, University of Valladolid, Valladolid. Spain.. bfuente@yahoo.es.
authors.forename: B
authors.initials: B
authors.lastname: de la Fuente
authors.affiliation: Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Dept Endocrinology and Nutrition, Hospital Clínico Universitario, University of Valladolid, Valladolid. Spain.. ozaola@yahoo.es.
authors.forename: O
authors.initials: O
authors.lastname: Izaola
authors.affiliation: Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Dept Endocrinology and Nutrition, Hospital Clínico Universitario, University of Valladolid, Valladolid. Spain.. tmartin@yahoo.es.
authors.forename: T
authors.initials: T
authors.lastname: Martin
authors.affiliation: Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Dept Endocrinology and Nutrition, Hospital Clínico Universitario, University of Valladolid, Valladolid. Spain.. cuellar@yahoo.es.
authors.forename: L
authors.initials: L
authors.lastname: Cuellar
authors.affiliation: Center of Investigation of Endocrinology and Clinical Nutrition, Medicine School and Dept Endocrinology and Nutrition, Hospital Clínico Universitario, University of Valladolid, Valladolid. Spain.. ccterroba@yahoo.es.
authors.forename: M C
authors.initials: MC
authors.lastname: Terroba
mesh_terms: D000368:Aged; D001835:Body Weight; D004043:Dietary Fiber / Q000008:administration & dosage*; D004044:Dietary Proteins / Q000008:administration & dosage*; D019587:Dietary Supplements; D002149:Energy Intake / Q000502:physiology*; D004750:Enteral Nutrition; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage*; D005260:Female; D006258:Head and Neck Neoplasms / Q000178:diet therapy / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D016896:Treatment Outcome
chemical_list: D004043:Dietary Fiber; D004044:Dietary Proteins; D015525:Fatty Acids, Omega-3