title: The Diamond Light Source and the challenges ahead for structural biology: some informal remarks.
abstract: The remarkable advances in structural biology in the past three decades have led to the determination of increasingly complex structures that lie at the heart of many important biological processes. Many of these advances have been made possible by the use of X-ray crystallography using synchrotron radiation. In this short article, some of the challenges and prospects that lie ahead will be summarized.
authors.affiliation: MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, UK ramak@mrc-lmb.cam.ac.uk.
authors.forename: V
authors.initials: V
authors.lastname: Ramakrishnan
mesh_terms: D001695:Biology / Q000295:instrumentation* / Q000379:methods*; D002621:Chemistry / Q000379:methods; D020285:Cryoelectron Microscopy; D018360:Crystallography, X-Ray; D004926:Escherichia coli / Q000378:metabolism; D006801:Humans; D046911:Macromolecular Substances; D009696:Nucleic Acids / Q000737:chemistry; D011506:Proteins / Q000737:chemistry; D012371:Robotics; D017356:Synchrotrons
chemical_list: D046911:Macromolecular Substances; D009696:Nucleic Acids; D011506:Proteins
keywords: macromolecular crystallography; structural biology; synchrotron radiation