title: Assembly of indoline-2-carboxylate-embodied dipeptides via Pd-catalyzed C(sp2)-H bond direct functionalization.
abstract: Intramolecular dehydrogenative cyclization of 2-methoxyiminoacyl-protected phenylalanine derivatives proceeded at 110 °C under catalysis of Pd(OAc)2 in the presence of 1-fluoro-2,4,6-trimethylpyridinium tetrafluoroborate to afford substituted indoline-2-carboxylates that were converted into indoline-2-carboxylate-embodied dipeptides via Raney Ni-catalyzed hydrogenation.
authors.affiliation: College of Chemistry, Chemical Engineering and Environmental Engineering, Liaoning Shihua University , Dandong Lu West 1, Fushun 113001, China.
authors.forename: Yu-Peng
authors.initials: YP
authors.lastname: He
authors.forename: Chao
authors.initials: C
authors.lastname: Zhang
authors.forename: Mengyang
authors.initials: M
authors.lastname: Fan
authors.forename: Zhijie
authors.initials: Z
authors.lastname: Wu
authors.forename: Dawei
authors.initials: D
authors.lastname: Ma
mesh_terms: D002264:Carboxylic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D004151:Dipeptides / Q000138:chemical synthesis* / Q000737:chemistry; D006865:Hydrogenation; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D004151:Dipeptides; D007211:Indoles; C000596456:indoline-2-carboxylate; D010165:Palladium; C057812:indoline