title: Primary implantation of type I Boston keratoprosthesis in nonautoimmune corneal diseases.
abstract: OBJECTIVE
  The aim of this study was to report outcomes of type I Boston keratoprosthesis (KPro) as primary corneal surgery in nonautoimmune corneal disorders.
  
  
  METHODS
  In this retrospective, observational, large single-center case series of 43 eyes (37 patients) that were followed for an average of 39 months (1-6 years), primary implantation of the type I Boston KPro was performed in all patients. Visual acuity at year 1, visual acuity at last follow-up, and postoperative complication rates were examined for all eyes.
  
  
  RESULTS
  Preoperative best-corrected visual acuity ranged from 20/60 to light perception, with vision of 20/200 or worse in 88%. Vision was ≥20/200 at 1 year in 77% of eyes (P < 0.0001). Complications included retroprosthetic membrane formation (51%), glaucoma progression (47%), corneal melt (19%), and sterile vitritis (14%).
  
  
  CONCLUSIONS
  In a large series with long follow-up, primary Boston KPro effectively restored vision. Close follow-up is needed to manage the known complications after Boston KPro.
authors.affiliation: Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA.
authors.forename: Han-Ying Peggy
authors.initials: HY
authors.lastname: Chang
authors.forename: Zhonghui Katie
authors.initials: ZK
authors.lastname: Luo
authors.forename: James
authors.initials: J
authors.lastname: Chodosh
authors.forename: Claes H
authors.initials: CH
authors.lastname: Dohlman
authors.forename: Kathryn A
authors.initials: KA
authors.lastname: Colby
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001187:Artificial Organs; D003316:Corneal Diseases / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D019736:Prostheses and Implants; D011474:Prosthesis Design; D019919:Prosthesis Implantation; D012189:Retrospective Studies; D014792:Visual Acuity