title: Declining relative risk for myocardial infarction among HIV-positive compared with HIV-negative individuals with access to care.
abstract: Concerns remain for an increased myocardial infarction (MI) risk among individuals infected with human immunodeficiency virus (HIV). We conducted a cohort study evaluating MI risk from 1996 to 2011 by HIV status. The adjusted MI rate ratio for HIV status declined over time, reaching 1.0 (95% confidence interval, .7-1.4) in 2010-2011, the most recent study period.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Kaiser Permanente, San Leandro.
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Klein
authors.affiliation: Division of Research, Kaiser Permanente, Oakland.
authors.forename: Wendy A
authors.initials: WA
authors.lastname: Leyden
authors.affiliation: Department of Research and Evaluation, Kaiser Permanente, Pasadena, California.
authors.forename: Lanfang
authors.initials: L
authors.lastname: Xu
authors.affiliation: Department of Research and Evaluation, Kaiser Permanente, Pasadena, California.
authors.forename: Chun R
authors.initials: CR
authors.lastname: Chao
authors.affiliation: Mid-Atlantic Permanente Research Institute, Rockville, Maryland.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Horberg
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, Kaiser Permanente, Los Angeles, California.
authors.forename: William J
authors.initials: WJ
authors.lastname: Towner
authors.affiliation: Division of Research, Kaiser Permanente, Oakland.
authors.forename: Leo B
authors.initials: LB
authors.lastname: Hurley
authors.affiliation: Division of Research, Kaiser Permanente, Oakland.
authors.forename: Julia L
authors.initials: JL
authors.lastname: Marcus
authors.affiliation: Division of Research, Kaiser Permanente, Oakland.
authors.forename: Charles P
authors.initials: CP
authors.lastname: Quesenberry
authors.affiliation: Division of Research, Kaiser Permanente, Oakland.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Silverberg
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology*; D012306:Risk; D055815:Young Adult
keywords: HIV; myocardial infarction; secular trend