title: Clinical characteristics and diagnostic imaging of cranial osteoblastoma.
abstract: Benign osteoblastoma is a rare, vascular, osteoid-forming bone tumor that occurs even less frequently in the cranial bones. Benign osteoblastoma of the cranium affects women slightly more often than men and typically presents in the first three decades of life. Although clinical presentation can vary depending on location, cranial osteoblastoma usually presents as a painful, non-mobile, subcutaneous mass or swelling. On CT scan, it generally presents as a well-demarcated, mixed lytic and sclerotic lesion, with enlarged diploe, thinning outer and/or inner tables, and varying degrees of calcification. It is hypo to isointense on T1-weighted MRI and has variable presentation on T2-weighted MRI. Gross total resection is the definitive treatment, while subtotal resection is utilized when it is necessary to preserve critical adjacent neurovascular structures.
authors.affiliation: Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Suite 562, 5th Floor Wasserman Building, Los Angeles, CA 90095-6901, USA.
authors.forename: Panayiotis E
authors.initials: PE
authors.lastname: Pelargos
authors.affiliation: Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Suite 562, 5th Floor Wasserman Building, Los Angeles, CA 90095-6901, USA.
authors.forename: Daniel T
authors.initials: DT
authors.lastname: Nagasawa
authors.affiliation: Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Suite 562, 5th Floor Wasserman Building, Los Angeles, CA 90095-6901, USA.
authors.forename: Nolan
authors.initials: N
authors.lastname: Ung
authors.affiliation: Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Suite 562, 5th Floor Wasserman Building, Los Angeles, CA 90095-6901, USA.
authors.forename: Lawrance K
authors.initials: LK
authors.lastname: Chung
authors.affiliation: Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Suite 562, 5th Floor Wasserman Building, Los Angeles, CA 90095-6901, USA.
authors.forename: Kimberly
authors.initials: K
authors.lastname: Thill
authors.affiliation: Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA, USA.
authors.forename: Stephen
authors.initials: S
authors.lastname: Tenn
authors.affiliation: Department of Head & Neck Surgery, University of California Los Angeles, Los Angeles, CA, USA.
authors.forename: Quinton
authors.initials: Q
authors.lastname: Gopen
authors.affiliation: Department of Neurological Surgery, University of California Los Angeles, 300 Stein Plaza, Suite 562, 5th Floor Wasserman Building, Los Angeles, CA 90095-6901, USA. Electronic address: iyang@mednet.ucla.edu.
authors.forename: Isaac
authors.initials: I
authors.lastname: Yang
mesh_terms: D017824:Bone Cysts, Aneurysmal / Q000175:diagnosis; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis; D018212:Giant Cell Tumor of Bone / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis; D008579:Meningioma / Q000175:diagnosis; D018215:Osteoblastoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010017:Osteoma, Osteoid / Q000175:diagnosis; D012516:Osteosarcoma / Q000175:diagnosis; D012886:Skull / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
keywords: Benign osteoblastoma; Cranial; Cranium; Osteoblastoma; Presentation; Radiology; Treatment