title: Saving two lives with one dialysis treatment.
abstract: Hemodialysis is the extracorporeal treatment of choice for various life-threatening intoxications, with the exception of highly protein-bound substances, which are preferably removed by charcoal hemoperfusion. This technique, however, is limited by its availability and its significant side effects. We present a potentially lifethreatening diphenhydramine (DPH) overdose in a stuporous female patient in which high cut-off hemodialysis was used. Timely detoxification resulted in rapid gain of consciousness, allowing the patient to state the existence and location of another poison victim.
authors.forename: Eva
authors.initials: E
authors.lastname: Baroke
authors.forename: Julius J
authors.initials: JJ
authors.lastname: Schmidt
authors.forename: Ann-Kathrin
authors.initials: AK
authors.lastname: Strunk
authors.forename: Olaf
authors.initials: O
authors.lastname: Wiesner
authors.forename: W Nikolaus
authors.initials: WN
authors.lastname: Kühn-Velten
authors.forename: Jan T
authors.initials: JT
authors.lastname: Kielstein
mesh_terms: D001714:Bipolar Disorder / Q000523:psychology; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D004155:Diphenhydramine / Q000506:poisoning*; D062787:Drug Overdose / Q000628:therapy*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000506:poisoning*; D010830:Physostigmine / Q000627:therapeutic use; D006435:Renal Dialysis / Q000379:methods*; D013406:Suicide, Attempted / Q000523:psychology; D055815:Young Adult
chemical_list: D002800:Cholinesterase Inhibitors; D006993:Hypnotics and Sedatives; D004155:Diphenhydramine; D010830:Physostigmine