title: [Necrotizing pneumonia associated with influenza A H1N1 infection in a child with mucopolysaccharidosis type II. Case report].
abstract: Mucopolysaccharidosis type II (MPS II) is an X-linked recessive disorder characterized by a deficiency of the enzyme iduronate-2-sulfatase leading to a multisystem involvement by tissue accumulation of glycosaminoglycans heparan and dermatan sulfate. We report a case of a 9-year-old boy diagnosed with mucopolysaccharidosis type II at 4 years of age, classified as severe variant. He presented necrotizing pneumonia associated with influenza A H1N1 infection, requiring mechanical ventilation for 1 month and 10 days. This case emphasizes the importance of healthcare workers to be aware of potentially lethal complications in patients with MPS II, such as influenza A H1N1 infection, which in turn may be associated with necrotizing pneumonia.
authors.affiliation: Facultad de Medicina San Fernando, Universidad Nacional Mayor de San Marcos.
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Huillca-Huerta
authors.affiliation: Facultad de Medicina San Fernando, Universidad Nacional Mayor de San Marcos.
authors.forename: Luis G
authors.initials: LG
authors.lastname: Yllescas-Estela
authors.affiliation: Facultad de Medicina San Fernando, Universidad Nacional Mayor de San Marcos.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Huerta-Medina
authors.affiliation: Facultad de Medicina San Fernando, Universidad Nacional Mayor de San Marcos.
authors.forename: Pedro E
authors.initials: PE
authors.lastname: San Martín-Howard
mesh_terms: D002648:Child; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000150:complications*; D008297:Male; D016532:Mucopolysaccharidosis II / Q000150:complications*; D000071067:Pneumonia, Necrotizing / Q000821:virology*