title: Hailey-Hailey disease improved by fractional CO2 laser.
abstract: Hailey-Hailey disease (HHD), also known as benign familial pemphigus, is an autosomal dominant skin condition that affects the adhesion of epidermal keratinocytes. Although the initial manifestation of flaccid vesicles on erythematous or normal skin in flexure sites frequently goes unnoticed, large, macerated, exudative plaques of superficial erosions with crusting are observed at the time of diagnosis. There is no specific treatment for HHD, and most cases are symptomatically supported. However, infrared laser ablation has been somewhat helpful. We present a case successfully treated with fractional CO2 laser showing a long-term favourable outcome and no adverse effects. Thus, this modality could be an alternative to full ablation for this condition.
authors.affiliation: Department of Dermatology, Hospital Central Dr. Ignacio Morones Prieto, Universidad Autónoma de San Luis Potosí , San Luis Potosi , México.
authors.forename: Andres Eduardo
authors.initials: AE
authors.lastname: Campuzano-García
authors.forename: Bertha
authors.initials: B
authors.lastname: Torres-Alvarez
authors.forename: Diana
authors.initials: D
authors.lastname: Hernández-Blanco
authors.forename: Juan Pablo
authors.initials: JP
authors.lastname: Castanedo-Cázares
mesh_terms: D000328:Adult; D003357:Cosmetic Techniques; D005260:Female; D006801:Humans; D054020:Lasers, Gas / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000379:methods*; D016506:Pemphigus, Benign Familial / Q000532:radiotherapy*
keywords: Hailey–Hailey disease; fractional CO2 laser