title: Effects of home-based respiratory muscle training in children and adolescents with chronic lung disease.
abstract: OBJECTIVE
  Respiratory muscle weakness is a functional repercussion of chronic lung disease (CLD). The objective of this study was to assess the effects of home-based respiratory muscle training (RMT) in children and adolescents with CLD or neuromuscular disease (NMD).
  
  
  METHODS
  This was a quasi-experimental study involving children and adolescents with CLD or NMD. Before and after 6 months of home-based RMT, we measured respiratory muscle strength (MIP and MEP), PEF, and peak cough flow (PCF). We made statistical comparisons between the pre-RMT and post-RMT values, as well as evaluating the correlation between the duration and effect of RMT.
  
  
  RESULTS
  The study included 29 patients, with a mean age of 12 years (range, 5-17 years), of whom 18 (62.1%) were male. The CLD group comprised 11 patients (37.9%), and the NMD group comprised 18 (62.1%). The mean duration of the RMT was 60 weeks (range, 46-90 weeks) in the CLD group and 39 weeks (range, 24-89 weeks) in the NMD group. In comparison with the pre-RMT values, the post-RMT values for MIP and MEP were significantly higher in both groups, whereas those for PEF and PCF were significantly higher only in the NMD group. We found no correlation between the duration and the effect of RMT.
  
  
  CONCLUSIONS
  Home-based RMT appears to be an effective strategy for increasing respiratory muscle strength in children and adolescents with CLD or NMD, although it increased the ability to cough effectively only in those with NMD.
authors.affiliation: San Sebastian University, Faculty of Health Science, Center of Molecular Medicine, Concepción, Chile. Center of Molecular Medicine, Faculty of Health Science, San Sebastian University. Concepción. Chile.
authors.forename: Iván Rodríguez
authors.initials: IR
authors.lastname: Núñez
authors.affiliation: Guillermo Grant Benavente Hospital, Department of Pediatrics, Concepción, Chile. Department of Pediatrics, Guillermo Grant Benavente Hospital, Concepción, Chile.
authors.forename: Daniel Zenteno
authors.initials: DZ
authors.lastname: Araos
authors.affiliation: Autonomous University, Center for Biomedical Research, Temuco, Chile. Center for Biomedical Research, Autonomous University, Temuco, Chile.
authors.forename: Carlos Manterola
authors.initials: CM
authors.lastname: Delgado
mesh_terms: D000293:Adolescent; D000403:Airway Resistance / Q000502:physiology; D001945:Breathing Exercises; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000503:physiopathology*; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D053580:Muscle Strength / Q000502:physiology*; D052580:Muscle Stretching Exercises; D009468:Neuromuscular Diseases / Q000503:physiopathology*; D012129:Respiratory Function Tests; D012132:Respiratory Muscles / Q000502:physiology*
keywords: Breathing exercises; Bronchiolitis obliterans; Cough; Cystic fibrosis; Neuromuscular diseases