title: Improvement of dilated cardiomyopathy with methylprednisolone in a patient with multiple fibrosclerosis.
abstract: Multifocal fibrosclerosis is a rare syndrome of unknown cause that is characterized by fibrosis involving multiple organ systems. Definitive diagnosis can only be made based on biopsy findings. In this case, the biopsy specimen of the patient demonstrates pulmonary hyalinated granuloma or sclerosing mediastinitis. There are few reports of multiple fibrosclerosis with heart failure. Here, we reported a case of retroperitoneal fibrosis with massive mediastinal involvement extending to pleura and pericardium causing pleuro- pericardial effusion with dilated cardiomyopathy. Systolic dysfunction was improved and pericardial effusion disappeared with methylprednisolone treatment.
authors.affiliation: Mugla Sitki Kocman University, Faculty of Medicine, Department of Cardiology, Mugla, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Altun
authors.affiliation: Istanbul University, Faculty of Medicine, Department of Cardiology, Istanbul, Turkey.
authors.forename: Goksel
authors.initials: G
authors.lastname: Guz
authors.affiliation: Mugla Sitki Kocman University, Faculty of Medicine, Department of Cardiology, Mugla, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Akin
authors.affiliation: Mugla Sitki Kocman University, Faculty of Medicine, Department of Cardiology, Mugla, Turkey.
authors.forename: Nuri
authors.initials: N
authors.lastname: Kose
authors.affiliation: Mugla Sitki Kocman University, Faculty of Medicine, Department of Radiology, Mugla, Turkey.
authors.forename: Ilknur
authors.initials: I
authors.lastname: Altun
authors.affiliation: Istanbul University, Faculty of Medicine, Department of Cardiology, Istanbul, Turkey.
authors.forename: Zeki Yuksel
authors.initials: ZY
authors.lastname: Gunaydin
authors.affiliation: Mugla Sitki Kocman University, Faculty of Medicine, Department of Internal Medicine, Mugla, Turkey.
authors.forename: Cem
authors.initials: C
authors.lastname: Sahin
keywords: Dilated Cardiomyopathy; Multifocal Fibrosclerosis; Myocarditis; Pulmonary Hyalinated Granuloma; Sclerosing Mediastinitis