title: A pilot study to evaluate the feasibility of individualized yoga for inpatient children receiving intensive chemotherapy.
abstract: BACKGROUND
  Fatigue is an important problem in paediatric cancer patients and yoga may be an effective intervention. The primary objective was to determine the feasibility of individualized yoga for hospitalized children receiving intensive chemotherapy.
  
  
  METHODS
  We included English-speaking children and adolescents aged 7-18 years receiving intensive chemotherapy or haematopoietic stem cell transplantation (HSCT). Yoga was conducted three times weekly for three weeks. The primary outcome was feasibility, defined as ability to deliver at least 60% of planned sessions. Secondary outcomes were parent-reported Pediatric Quality of Life Inventory (PedsQL) Multidimensional Fatigue Scale, Fatigue Scale-Parent, PedsQL Generic Core Scales and PedsQL Acute Cancer Module.
  
  
  RESULTS
  Between January and October 2013, 11 patients were enrolled. Median age was 14.0 (range 7.7-16.4) years and 6 (55%) were boys. Yoga was feasible with 10/11 participants meeting the threshold for feasibility. The median number of yoga sessions was 9 (range 3-13). No adverse events were attributed to yoga. Mean±standard deviation for the day 21 proxy-reported PedsQL general fatigue scores was 55.6±15.5. Qualitative comments suggested design changes for future yoga studies.
  
  
  CONCLUSIONS
  Individualized yoga is feasible for inpatient children receiving intensive chemotherapy. Future work will include development and conduct of a randomized trial for fatigue amelioration.
  
  
  BACKGROUND
  ClinicalTrials.gov NCT02105389.
authors.forename: Caroline
authors.initials: C
authors.lastname: Diorio
authors.forename: Tal
authors.initials: T
authors.lastname: Schechter
authors.forename: Michelle
authors.initials: M
authors.lastname: Lee
authors.forename: Cathy
authors.initials: C
authors.lastname: O'Sullivan
authors.forename: Tanya
authors.initials: T
authors.lastname: Hesser
authors.forename: Deborah
authors.initials: D
authors.lastname: Tomlinson
authors.forename: Janine
authors.initials: J
authors.lastname: Piscione
authors.forename: Christine
authors.initials: C
authors.lastname: Armstrong
authors.forename: George
authors.initials: G
authors.lastname: Tomlinson
authors.forename: Lillian
authors.initials: L
authors.lastname: Sung
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002648:Child; D005221:Fatigue / Q000150:complications / Q000209:etiology; D005240:Feasibility Studies; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007297:Inpatients; D008297:Male; D009369:Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000628:therapy*; D010290:Parents; D010865:Pilot Projects; D057285:Precision Medicine / Q000009:adverse effects / Q000379:methods*; D011788:Quality of Life; D015013:Yoga
chemical_list: D000970:Antineoplastic Agents