title: Transcription initiation determines its end.
abstract: A new study published in this issue of Molecular Cell (Oktaba et al., 2015) suggests widespread involvement of promoters in the regulation of alternative cleavage and polyadenylation of mRNAs in Drosophila neurons.
authors.affiliation: Division of Biological Stress Response, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.
authors.forename: Boris
authors.initials: B
authors.lastname: Slobodin
authors.affiliation: Division of Biological Stress Response, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands; Erasmus MC, Rotterdam University, 3000 CA Rotterdam, The Netherlands. Electronic address: r.agami@nki.nl.
authors.forename: Reuven
authors.initials: R
authors.lastname: Agami
mesh_terms: D000818:Animals; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000378:metabolism*; D051959:ELAV Proteins / Q000378:metabolism*; D026723:Polyadenylation; D012319:RNA Polymerase II / Q000378:metabolism*
chemical_list: D029721:Drosophila Proteins; D051959:ELAV Proteins; C498009:ELAV protein, Drosophila; D012319:RNA Polymerase II