title: Trace elements in children suffering from idiopathic nephrotic syndrome.
abstract: OBJECTIVE
  Trace elements play a significant role in several metabolic processes and often circulate in the blood binding to protein. The purpose of this study was to determine the status of selenium, zinc, and boron in idiopathic nephrotic syndrome patients in active and remission phases.
  
  
  METHODS
  Fourteen patients and fourteen healthy age-matched controls were included in the study. The selenium, zinc and boron level in plasma and urine were measured by the inductively coupled plasma mass spectrometry.
  
  
  RESULTS
  The plasma levels of zinc and selenium were significantly lower in both active and remission patients (for all p=0.0001). The plasma boron level was significantly lower only in patients in active phase (p=0.0002 vs control). The concentrations of urinary boron and selenium were significantly higher during active phase compared with remission (p=0.0003 and 0.0001, respectively).
  
  
  CONCLUSIONS
  Supplementation with zinc, selenium and boron may be justified in patients suffering with this disease.
authors.affiliation: Department of Pediatric Nephrology, Erciyes University Faculty of Medicine, Kayseri, Turkey.
authors.forename: Sebahat
authors.initials: S
authors.lastname: Tulpar
authors.affiliation: Department of Pediatric Nephrology, Erciyes University Faculty of Medicine, Kayseri, Turkey.
authors.forename: Zubeyde
authors.initials: Z
authors.lastname: Gunduz
authors.affiliation: Department of Chemistry, Erciyes University Faculty of Arts and Sciences, Kayseri, Turkey.
authors.forename: Ugur
authors.initials: U
authors.lastname: Sahin
authors.affiliation: Department of Pediatric Nephrology, Erciyes University Faculty of Medicine, Kayseri, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Hakan Poyrazoglu
authors.affiliation: Department of Pediatric Nephrology, Erciyes University Faculty of Medicine, Kayseri, Turkey.
authors.forename: Ismail
authors.initials: I
authors.lastname: Dursun
authors.affiliation: Department of Pediatric Nephrology, Erciyes University Faculty of Medicine, Kayseri, Turkey.
authors.forename: Ruhan
authors.initials: R
authors.lastname: Dusunsel
authors.affiliation: Department of Pediatric Nephrology, Erciyes University Faculty of Medicine, Kayseri, Turkey.
authors.forename: Funda
authors.initials: F
authors.lastname: Bastug
keywords: Boron; children; nephrotic syndrome; selenium; zinc