title: Decreased repolarization reserve increases defibrillation threshold by favoring early afterdepolarizations in an in silico model of human ventricular tissue.
authors.affiliation: Department of Physics and Astronomy, Ghent University, Ghent, Belgium. Electronic address: Nele.Vandersickel@ugent.be.
authors.forename: Nele
authors.initials: N
authors.lastname: Vandersickel
authors.affiliation: Department of Physics and Astronomy, Ghent University, Ghent, Belgium.
authors.forename: Ivan V
authors.initials: IV
authors.lastname: Kazbanov
authors.affiliation: Department of Physics and Astronomy, Ghent University, Ghent, Belgium.
authors.forename: Arne
authors.initials: A
authors.lastname: Defauw
authors.affiliation: Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Daniël A
authors.initials: DA
authors.lastname: Pijnappels
authors.affiliation: Department of Physics and Astronomy, Ghent University, Ghent, Belgium; Laboratory of Mathematical Modeling in Physiology and Medicine, Ural Federal University, Ekaterinburg, Russia.
authors.forename: Alexander V
authors.initials: AV
authors.lastname: Panfilov
mesh_terms: D003198:Computer Simulation; D004554:Electric Countershock / Q000379:methods*; D022062:Electrophysiologic Techniques, Cardiac / Q000379:methods; D055724:Electrophysiological Phenomena; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D008955:Models, Cardiovascular; D014693:Ventricular Fibrillation / Q000503:physiopathology / Q000628:therapy
keywords: Defibrillation threshold; Early afterdepolarization; In silico; Ventricular fibrillation