title: Palladium-catalyzed diastereoselective oxyarylation of 2-alkylindoles.
abstract: Diastereoselective oxyarylation of N-protected 2-alkylindoles with commercially available boronic acids and TEMPO as a mild oxidant to give N-protected 2-aryl-2-alkyl-3-(2-chloroacetoxy)indolines is described. Reactions are easy to conduct, and product indolines containing a fully substituted C-center are obtained in good yields with good to excellent selectivities.
authors.affiliation: Organic Chemistry Institute, Westfälische Wilhelms-University , Corrensstraße 40, 48149 Münster, Germany.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Ramella
authors.forename: Zhiheng
authors.initials: Z
authors.lastname: He
authors.forename: Constantin G
authors.initials: CG
authors.lastname: Daniliuc
authors.forename: Armido
authors.initials: A
authors.lastname: Studer
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001897:Boronic Acids; D007211:Indoles; D010165:Palladium; C057812:indoline