title: Molecular breast imaging: an emerging modality for breast cancer screening.
abstract: Screening mammography is recognized as an imperfect imaging tool that performs poorly in women with dense breast tissue - a limitation which has driven demand for supplemental screening techniques. One potential supplemental technique is molecular breast imaging (MBI). Significant improvements in gamma camera technology allow MBI to be performed at low radiation doses, comparable with those of tomosynthesis and mammography. A recent screening trial in women with dense breast tissue yielded a cancer detection rate of 3.2 per 1000 for mammography alone and 12.0 per 1000 for the combination of mammography and MBI. MBI also demonstrated a lower recall rate than that of mammography. MBI is a promising supplemental screening technique in women with dense breast tissue.
authors.affiliation: Department of Radiology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA; Tel.: +1 507 284 7083;
authors.forename: Michael K
authors.initials: MK
authors.lastname: O'Connor
keywords: Tc-99m sestamibi; dense breast; mammography; molecular breast imaging; nuclear medicine; radiation dose; screening