title: Use of computational fluid dynamics in respiratory medicine.
abstract: Computational Fluid Dynamics (CFD) is a computer-based tool for simulating fluid movement. The main advantages of CFD over other fluid mechanics studies include: substantial savings in time and cost, the analysis of systems or conditions that are very difficult to simulate experimentally (as is the case of the airways), and a practically unlimited level of detail. We used the Ansys-Fluent CFD program to develop a conducting airway model to simulate different inspiratory flow rates and the deposition of inhaled particles of varying diameters, obtaining results consistent with those reported in the literature using other procedures. We hope this approach will enable clinicians to further individualize the treatment of different respiratory diseases.
authors.affiliation: Instituto Nacional de Silicosis, Hospital Universitario Central de Asturias, Facultad de Medicina, Universidad de Oviedo, Oviedo, España.
authors.forename: Ana
authors.initials: A
authors.lastname: Fernández Tena
authors.affiliation: Instituto Nacional de Silicosis, Hospital Universitario Central de Asturias, Facultad de Medicina, Universidad de Oviedo, Oviedo, España. Electronic address: pcasan@ins.es.
authors.forename: Pere
authors.initials: P
authors.lastname: Casan Clarà
mesh_terms: D000336:Aerosols; D000388:Air; D000465:Algorithms; D003198:Computer Simulation / Q000191:economics; D006801:Humans; D057446:Hydrodynamics; D001239:Inhalation / Q000502:physiology*; D008953:Models, Anatomic; D008954:Models, Biological; D010316:Particle Size; D052638:Particulate Matter / Q000493:pharmacokinetics; D057285:Precision Medicine; D015272:Pulmonary Medicine / Q000191:economics / Q000379:methods*; D012123:Pulmonary Ventilation; D012137:Respiratory System / Q000033:anatomy & histology; D012212:Rheology
chemical_list: D000336:Aerosols; D052638:Particulate Matter
keywords: Aerosol; Computational fluid dynamics; Depósito pulmonar; Dinámica de fluidos computacional; Lung deposit