title: Giant Hemosiderotic Dermatofibroma: The Largest Giant Dermatofibroma Reported to Date.
abstract: Dermatofibroma (DF) is a relatively common benign fibrohistiocytic soft tissue tumor. It has a slightly greater incidence amongst females and typically presents itself during the midadult life as a slowly growing, firm dermal nodule, usually smaller than 2 cm in diameter, on the lower extremities. Giant DF is a rare clinical variant of DF characterized by unusually large size (>5 cm), which mimics malignant soft tissue tumor clinically. Twenty-six cases of giant DF have been reported so far. One of these giant DFs was a giant hemosiderotic DF. We report herein a case of a 47-year-old woman who presented with the largest DF reported in the literature to date. It was hemosiderotic.
authors.affiliation: *University of Vermont College of Medicine, Burlington, VT; and Departments of †Surgery, and ‡Pathology, United Health Services Hospitals, Johnson City, NY.
authors.forename: Herman
authors.initials: H
authors.lastname: Kalsi
authors.forename: Anishur
authors.initials: A
authors.lastname: Rahman
authors.forename: Tracy
authors.initials: T
authors.lastname: Harbol
authors.forename: Jagmohan
authors.initials: J
authors.lastname: Sidhu
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D018223:Dermatofibrosarcoma / Q000737:chemistry / Q000150:complications / Q000473:pathology* / Q000601:surgery; D005260:Female; D006485:Hemosiderin / Q000032:analysis; D006486:Hemosiderosis / Q000175:diagnosis / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D012878:Skin Neoplasms / Q000737:chemistry / Q000150:complications / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome; D047368:Tumor Burden
chemical_list: D014408:Biomarkers, Tumor; D006485:Hemosiderin