title: [Seroprevalence and detection of primary infection by cytomegalovirus with IgG avidity test during the first quarter of pregnancy].
abstract: OBJECTIVE
  To determine the seroprevalence and detection of primary infection by cytomegalovirus (CMV) with immunoglobulin G (IgG) avidity test during the first quarter of pregnancy in the General Hospital in Morelia, Michoacan.
  
  
  METHODS
  A total of 177 patients were studied employing a modified Elisa test using a chemiluminescent microparticle immunoassay (CMIA) for the detection of CMV antibodies (IgG and immunoglobulin M [IgM]), and IgG avidity.
  
  
  RESULTS
  90.4% were positive for IgG, and of these, 2.3% were also reactive for IgM, and in this group the IgG avidity test reported low avidity for 1.1% and higher avidity in the same percentage. 9.6% were seronegative.
  
  
  CONCLUSIONS
  Similarity was found with published studies in Mexico. Health professionals should know the clinical algorithms for diagnosis and proper management of CMV infection using the IgG avidity test.
authors.affiliation: Instituto de Ciencias y Estudios Superiores de Tamaulipas, Morelia, Michoacán, México.
authors.forename: Conne L
authors.initials: CL
authors.lastname: González-García
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Reyes-Méndez
authors.affiliation: Facultad de Ciencias Médicas y Biológicas Dr. Ignacio Chávez, Universidad Michoacana de San Nicolás de Hidalgo.
authors.forename: Luz E
authors.initials: LE
authors.lastname: Ortega-Pierres
authors.affiliation: Servi-Med, Morelia, Michoacán, México.
authors.forename: Adriana P
authors.initials: AP
authors.lastname: Rodríguez-Sánchez
authors.affiliation: Servi-Med, Morelia, Michoacán, México.
authors.forename: Verónica
authors.initials: V
authors.lastname: Sandoval-Guido
authors.affiliation: Facultad de Ciencias Médicas y Biológicas Dr. Ignacio Chávez, Universidad Michoacana de San Nicolás de Hidalgo.
authors.forename: José A
authors.initials: JA
authors.lastname: Sereno-Coló
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D000915:Antibody Affinity; D003430:Cross-Sectional Studies; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000453:epidemiology*; D005260:Female; D006769:Hospitals, General / Q000706:statistics & numerical data; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D011261:Pregnancy Trimester, First; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G