title: Oncologic outcomes of volume replacement technique after partial mastectomy for breast cancer: a single center analysis.
abstract: OBJECTIVE
  Volume replacement technique is a good option for Asian women with small to moderate-sized breasts undergoing partial mastectomy for breast cancer. We analyzed the oncologic outcomes of this procedure in a single center.
  
  
  METHODS
  Seventy-two patients with breast cancer underwent partial mastectomy with volume replacement technique in this prospective study. Volume replacement techniques were tailored individually according to the volume of excised breast and tumor location. The mean duration of follow-up was 40.9 months. We analyzed association between various clinicopathologic factors and locoregional recurrence, distant metastasis and assessed cosmetic outcomes.
  
  
  RESULTS
  The incidences of locoregional recurrence and distant metastasis were 2.8% and 5.6%, respectively. According to multivariate analysis, history of contralateral breast cancer (P < 0.001) and fat necrosis (P = 0.002) significantly associated with incidence of locoregional recurrence and pathologic tumor size (P = 0.037) and stage (P = 0.048) significantly influenced the incidence of distant metastasis.
  
  
  CONCLUSIONS
  From an oncologic perspective, volume replacement procedures after partial mastectomy are an appropriate form of surgical management of breast cancer.
authors.affiliation: Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea.
authors.forename: Jeeyeon
authors.initials: J
authors.lastname: Lee
authors.affiliation: Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea.
authors.forename: Jin Hyang
authors.initials: JH
authors.lastname: Jung
authors.affiliation: Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea.
authors.forename: Wan Wook
authors.initials: WW
authors.lastname: Kim
authors.affiliation: Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea.
authors.forename: Seung Ook
authors.initials: SO
authors.lastname: Hwang
authors.affiliation: Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea.
authors.forename: Jin Gu
authors.initials: JG
authors.lastname: Kang
authors.affiliation: Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea.
authors.forename: Jino
authors.initials: J
authors.lastname: Baek
authors.affiliation: Department of Plastic and Reconstructive Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea.
authors.forename: Jung Dug
authors.initials: JD
authors.lastname: Yang
authors.affiliation: Department of Plastic and Reconstructive Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea.
authors.forename: Jeong Woo
authors.initials: JW
authors.lastname: Lee
authors.affiliation: Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea. Electronic address: phy123@knu.ac.kr.
authors.forename: Ho Yong
authors.initials: HY
authors.lastname: Park
mesh_terms: D000046:Academic Medical Centers; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D016462:Mammaplasty / Q000379:methods; D015412:Mastectomy, Segmental / Q000379:methods; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology* / Q000473:pathology; D019651:Plastic Surgery Procedures; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors
keywords: Breast carcinoma; Distant metastasis; Locoregional recurrence; Partial mastectomy; Reconstruction