title: European cancer mortality predictions for the year 2015: does lung cancer have the highest death rate in EU women?
abstract: BACKGROUND
  Cancer mortality statistics for 2015 were projected from the most recent available data for the European Union (EU) and its six more populous countries. Prostate cancer was analysed in detail.
  
  
  METHODS
  Population and death certification data from stomach, colorectum, pancreas, lung, breast, uterus, prostate, leukaemias and total cancers were obtained from the World Health Organisation database and Eurostat. Figures were derived for the EU, France, Germany, Italy, Poland, Spain and the UK. Projected 2015 numbers of deaths by age group were obtained by linear regression on estimated numbers of deaths over the most recent time period identified by a joinpoint regression model.
  
  
  RESULTS
  A total of 1,359,100 cancer deaths are predicted in the EU in 2015 (766,200 men and 592,900 women), corresponding to standardised death rates of 138.4/100,000 men and 83.9/100,000 women, falling 7.5% and 6%, respectively, since 2009. In men, predicted rates for the three major cancers (lung, colorectum and prostate) are lower than in 2009, falling 9%, 5% and 12%. Prostate cancer showed predicted falls of 14%, 17% and 9% in the 35-64, 65-74 and 75+ age groups. In women, breast and colorectal cancers had favourable trends (-10% and -8%), but predicted lung cancer rates rise 9% to 14.24/100,000 becoming the cancer with the highest rate, reaching and possibly overtaking breast cancer rates--though the total number of deaths remain higher for breast (90 800) than lung (87 500). Pancreatic cancer has a negative outlook in both sexes, rising 4% in men and 5% in women between 2009 and 2015.
  
  
  CONCLUSIONS
  Cancer mortality predictions for 2015 confirm the overall favourable cancer mortality trend in the EU, translating to an overall 26% fall in men since its peak in 1988, and 21% in women, and the avoidance of over 325,000 deaths in 2015 compared with the peak rate.
authors.affiliation: Department of Epidemiology, IRCCS-Istituto di Ricerche Farmacologiche 'Mario Negri', Milan; Department of Clinical Sciences and Community Health, Universitá degli Studi di Milano, Milan, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Malvezzi
authors.affiliation: Department of Epidemiology, IRCCS-Istituto di Ricerche Farmacologiche 'Mario Negri', Milan.
authors.forename: P
authors.initials: P
authors.lastname: Bertuccio
authors.affiliation: Department of Clinical Sciences and Community Health, Universitá degli Studi di Milano, Milan, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Rosso
authors.affiliation: Department of Epidemiology, IRCCS-Istituto di Ricerche Farmacologiche 'Mario Negri', Milan.
authors.forename: M
authors.initials: M
authors.lastname: Rota
authors.affiliation: Cancer Epidemiology Unit, Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne, Switzerland.
authors.forename: F
authors.initials: F
authors.lastname: Levi
authors.affiliation: Department of Clinical Sciences and Community Health, Universitá degli Studi di Milano, Milan, Italy. Electronic address: carlo.lavecchia@unimi.it.
authors.forename: C
authors.initials: C
authors.lastname: La Vecchia
authors.affiliation: Department of Epidemiology, IRCCS-Istituto di Ricerche Farmacologiche 'Mario Negri', Milan.
authors.forename: E
authors.initials: E
authors.lastname: Negri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005062:European Union; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008175:Lung Neoplasms / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D009026:Mortality / Q000639:trends*; D009367:Neoplasm Staging; D009369:Neoplasms / Q000401:mortality*; D011379:Prognosis; D015996:Survival Rate; D013997:Time Factors; D016387:Women's Health; D055815:Young Adult
keywords: Europe; cancer; mortality; projections; prostate cancer; time trends