title: [Pathogenesis of premature ejaculation: a neurobiological approach].
abstract: Premature ejaculation (PE) is a most common male sexual dysfunction with complex pathogenesis. An increasing number of scholars agree that PE is a disorder associated with abnormal neurobiology, which involves the central neurotransmitter system, peripheral nerve function of the nerve tissue structure, and neurological biochemistry. This review focuses on the neurobiological mechanisms of PE, expecting to gain a deeper insight into the possible etiology, objective and reliable diagnostic methods, and individualized treatment of the disease.
authors.affiliation: Department of Urology, First Affiliated Hospital of Nanjing Medical University, Jiangsu, China.
authors.forename: Jia-Dong
authors.initials: JD
authors.lastname: Xia
authors.forename: Yu-Tian
authors.initials: YT
authors.lastname: Dai
mesh_terms: D001669:Biochemical Phenomena; D004542:Ejaculation; D006801:Humans; D008297:Male; D018377:Neurotransmitter Agents / Q000502:physiology; D017933:Peripheral Nervous System / Q000503:physiopathology; D061686:Premature Ejaculation / Q000209:etiology*
chemical_list: D018377:Neurotransmitter Agents