title: MicroRNA landscape in Alzheimer's disease.
abstract: Individual microRNAs and/or microRNA signatures were associated with Alzheimer's disease (AD). We report here the recent advances brought to the identification of microRNA changes in AD brain and their biological function in the molecular pathways associated with the disease. This field represents a fertile route to understand the pathogenic mechanisms underlying Alzheimer's disease. In addition we review recent studies aimed to discover promising biomarkers for AD diagnosis by microRNA expression profiles of biofluids from AD patients.
authors.forename: Carlo
authors.initials: C
authors.lastname: Cogoni
authors.forename: Francesca
authors.initials: F
authors.lastname: Ruberti
authors.affiliation: Institute of Cell Biology and Neurobiology (IBCN), National Research Council (CNR), Via del Fosso di Fiorano, 64 00143 Roma, Italy. christian.barbato@cnr.it.
authors.forename: Christian
authors.initials: C
authors.lastname: Barbato
mesh_terms: D000544:Alzheimer Disease / Q000378:metabolism* / Q000473:pathology*; D001921:Brain / Q000378:metabolism*; D006801:Humans; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism*
chemical_list: D035683:MicroRNAs