title: The role of vitamin D in malaria.
abstract: An abnormal calcium-parathyroid hormone (PTH)-vitamin D axis has been reported in patients with malaria infection. A role for vitamin D in malaria has been suggested by many studies. Genetic studies have identified numerous factors that link vitamin D to malaria, including human leukocyte antigen genes, toll-like receptors, heme oxygenase-1, angiopoietin-2, cytotoxic T lymphocyte antigen-4, nucleotide-binding oligomerization domain-like receptors, and Bcl-2. Vitamin D has also been implicated in malaria via its effects on the Bacillus Calmette-Guerin (BCG) vaccine, matrix metalloproteinases, mitogen-activated protein kinase pathways, prostaglandins, reactive oxidative species, and nitric oxide synthase. Vitamin D may be important in malaria; therefore, additional research on its role in malaria is needed.
authors.affiliation: Vietnamese American Medical Research Foundation, Westminster, California, United States. lng2687765@aol.com.
authors.forename: Khanh Vinh Quốc
authors.initials: KV
authors.lastname: Lương
authors.forename: Lan Thi Hoàng
authors.initials: LT
authors.lastname: Nguyễn
mesh_terms: D006801:Humans; D008288:Malaria / Q000453:epidemiology*; D014807:Vitamin D / Q000494:pharmacology*
chemical_list: D014807:Vitamin D