title: Recombinant human bone morphogenetic protein type 2 in the reconstruction of atrophic maxilla: Case report with long-term follow-up.
abstract: Autologous bone is reported by scientific literature as the gold standard for the replacement of the bone loss in maxillary atrophic area. Notwithstanding, this grafting type shows several disadvantages as: The procedure morbidity, limited size of the graft and longer recovering time. Recombinant human bone morphogenetic protein type 2 (rhBMP-2) has been used as bone substitute for the reconstruction of large bone defects. The aim of this case was to report a clinical case exhibiting the reconstruction of the atrophic maxilla through using rhBMP-2 as grafting material associated with absorbable collagen sponge (ACS). At 8 months of following-up, osseointegrated implants were placed. After 2 years and 5 months of following-up, it could be observed an appropriate aesthetical and functional rehabilitation.
authors.affiliation: Oral and Maxillofacial Surgeon, Chairman of Implantology, SOEPAR, Curitiba, PR, Brazil.
authors.forename: André Luiz
authors.initials: AL
authors.lastname: Zétola
authors.affiliation: Professor of Positivo University, Curitiba, PR, Brazil.
authors.forename: Thalyta
authors.initials: T
authors.lastname: Verbicaro
authors.affiliation: Private Pratice, Curitiba, PR, Brazil.
authors.forename: Sahara
authors.initials: S
authors.lastname: Littieri
authors.affiliation: Private Pratice, Curitiba, PR, Brazil.
authors.forename: Rafaela
authors.initials: R
authors.lastname: Larson
authors.affiliation: Professor of Positivo University, Curitiba, PR, Brazil.
authors.forename: Allan Fernando
authors.initials: AF
authors.lastname: Giovanini
authors.affiliation: Private Pratice, Curitiba, PR, Brazil.
authors.forename: Tatiana Miranda
authors.initials: TM
authors.lastname: Deliberador
keywords: Bone regeneration; bone transplantation; dental implants; intercellular signaling peptides and proteins