title: [Workers with Ehlers-Danlos syndrome: indications for health surveillance and suitable job assignment].
abstract: BACKGROUND
  In Europe 23.5% of the working-age population suffers from chronic or rare diseases, including Ehlers-Danlos syndrome (EDS), an inherited disorder of the connective tissue that frequently leads to impairment also at work.
  
  
  OBJECTIVE
  We sought to evaluate the impairment of different functional areas in EDS subjects, using EDS-Disability Test (EDS-DT) (7 visual analogical scales: pain, stiffness, daily activities of life, in the home, outside the home, at work, in social relationships).
  
  
  METHODS
  We administered the EDS-DT to 50 workers with EDS (classic type n=35, hypermobile n=14, vascular n=3) and 150 healthy workers (non-EDS).
  
  
  RESULTS
  EDS subjects showed higher perceived disability (median 29.31 vs 7.22, p&lt; 0.0001) than non-EDS. We observed a trend suggesting that the hypermobile type has a higher level of pain (54 vs 42) and work impairment (62.5 vs 42.5) (p&gt;0.20), whereas the classic type has greater impairment of daily living activities (18.57 vs 11.43) and in the home (34.29 vs 25.71) (p&gt;0.20). Subjects reporting moderate-to-vigorous occupational physical activities (OPA) showed a higher disability level in the work area (p=0.04).
  
  
  CONCLUSIONS
  People with EDS suffer from chronic pain, impaired quality of life and employment difficulties. The hypermobile type seems more compromised in functional areas such as pain and work, while the classic type is more compromised in daily routine and home activities. The employment section was more impaired for EDS subjects who perform tasks with greater physical effort.
authors.affiliation: Scuola di Specializzazione in Medicina del Lavoro - Università degli Studi di Milano. monica.bogni@libero.it.
authors.forename: Monica
authors.initials: M
authors.lastname: Bogni
authors.forename: Alessandra
authors.initials: A
authors.lastname: Bassotti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Leocata
authors.forename: Francesco
authors.initials: F
authors.lastname: Barretta
authors.forename: Amelia
authors.initials: A
authors.lastname: Brunani
authors.forename: Pier Alberto
authors.initials: PA
authors.lastname: Bertazzi
authors.forename: Luciano
authors.initials: L
authors.lastname: Riboldi
authors.forename: Luisella Maria
authors.initials: LM
authors.lastname: Vigna
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D059350:Chronic Pain / Q000209:etiology*; D004535:Ehlers-Danlos Syndrome / Q000145:classification / Q000150:complications / Q000175:diagnosis*; D004651:Employment; D005062:European Union; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011159:Population Surveillance; D011788:Quality of Life; D035583:Rare Diseases; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D014938:Work Capacity Evaluation; D055815:Young Adult