title: Reward Motivation Enhances Task Coding in Frontoparietal Cortex.
abstract: Reward motivation often enhances task performance, but the neural mechanisms underlying such cognitive enhancement remain unclear. Here, we used a multivariate pattern analysis (MVPA) approach to test the hypothesis that motivation-related enhancement of cognitive control results from improved encoding and representation of task set information. Participants underwent two fMRI sessions of cued task switching, the first under baseline conditions, and the second with randomly intermixed reward incentive and no-incentive trials. Information about the upcoming task could be successfully decoded from cue-related activation patterns in a set of frontoparietal regions typically associated with task control. More critically, MVPA classifiers trained on the baseline session had significantly higher decoding accuracy on incentive than non-incentive trials, with decoding improvement mediating reward-related enhancement of behavioral performance. These results strongly support the hypothesis that reward motivation enhances cognitive control, by improving the discriminability of task-relevant information coded and maintained in frontoparietal brain regions.
authors.affiliation: Washington University in St Louis, St Louis, MO, USA.
authors.forename: Joset A
authors.initials: JA
authors.lastname: Etzel
authors.affiliation: Washington University in St Louis, St Louis, MO, USA Rutgers University, Newark, NJ, USA.
authors.forename: Michael W
authors.initials: MW
authors.lastname: Cole
authors.affiliation: Washington University in St Louis, St Louis, MO, USA.
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Zacks
authors.affiliation: Washington University in St Louis, St Louis, MO, USA.
authors.forename: Kendrick N
authors.initials: KN
authors.lastname: Kay
authors.affiliation: Washington University in St Louis, St Louis, MO, USA.
authors.forename: Todd S
authors.initials: TS
authors.lastname: Braver
mesh_terms: D000328:Adult; D001931:Brain Mapping / Q000379:methods; D003463:Cues; D056344:Executive Function / Q000502:physiology*; D005260:Female; D005625:Frontal Lobe / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009042:Motivation / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D010296:Parietal Lobe / Q000502:physiology*; D011597:Psychomotor Performance; D012201:Reward; D014796:Visual Perception / Q000502:physiology; D055815:Young Adult
keywords: MVPA; cognitive control; fMRI; motivation; prefrontal