title: [Anaphylactic shock after intradermal injection of corticosteroid].
abstract: Carboxymethylcellulose (CMC) is a derivative of cellulose found in many food products, pharmaceuticals and cosmetics. Allergy to CMC in parenteral corticosteroid preparations leading to anaphylaxis is rare, but has previously been reported. We report a case of a 52-year-old woman with prurigo nodularis of Hyde, who reacted with anaphylaxis after intradermal injection of Kenalog 40 mg/ml. Allergy testing showed a positive skin prick test for CMC and the patient was advised to avoid future parenteral exposure to CMC. This case highlights the need to examine excipients in severe cases of drug allergy.
authors.affiliation: Hud- og Allergiafdeling, Gentofte Hospital, Niels Andersens Vej 65, 2900 Hellerup. martin.willy.meyer.01@regionh.dk.
authors.forename: Martin Willy
authors.initials: MW
authors.lastname: Meyer
authors.forename: Claus
authors.initials: C
authors.lastname: Zachariae
authors.forename: Lene Heise
authors.initials: LH
authors.lastname: Garvey
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced* / Q000188:drug therapy; D002266:Carboxymethylcellulose Sodium / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects / Q000737:chemistry; D006801:Humans; D007271:Injections, Intradermal; D008875:Middle Aged; D014222:Triamcinolone Acetonide / Q000009:adverse effects / Q000737:chemistry
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide; D002266:Carboxymethylcellulose Sodium