title: Emergency Ebola response: a new approach to the rapid design and development of vaccines against emerging diseases.
abstract: The epidemic of Ebola virus disease has spread at an alarming rate despite containment efforts. As a result, unprecedented large-scale international response efforts have been made in an attempt to gain control of the outbreak and reduce transmission. Several international consortia have been formed in a remarkable worldwide collaborative effort to expedite trials of two candidate Ebola virus vaccines: cAd3-EBOZ and rVSV-EBOV. In parallel, both vaccines are being manufactured in large amounts to enable future rapid deployment for management of the crisis.
authors.affiliation: Jenner Institute, University of Oxford, Oxford, UK. Electronic address: claire.tully@ndm.ox.ac.uk.
authors.forename: Claire M
authors.initials: CM
authors.lastname: Tully
authors.affiliation: Jenner Institute, University of Oxford, Oxford, UK.
authors.forename: Teresa
authors.initials: T
authors.lastname: Lambe
authors.affiliation: Jenner Institute, University of Oxford, Oxford, UK.
authors.forename: Sarah C
authors.initials: SC
authors.lastname: Gilbert
authors.affiliation: Jenner Institute, University of Oxford, Oxford, UK.
authors.forename: Adrian V S
authors.initials: AV
authors.lastname: Hill
mesh_terms: D002986:Clinical Trials as Topic; D004196:Disease Outbreaks; D046129:Ebola Vaccines / Q000276:immunology* / Q000302:isolation & purification*; D029043:Ebolavirus / Q000276:immunology* / Q000302:isolation & purification; D019142:Hemorrhagic Fever, Ebola / Q000453:epidemiology* / Q000517:prevention & control*; D006801:Humans; D007391:International Cooperation
chemical_list: D046129:Ebola Vaccines