title: On-chip monitoring of chemical syntheses in microdroplets via surface-enhanced Raman spectroscopy.
abstract: Conducting organic syntheses in microfluidic chips allows studying and optimising chemical reactions at minimal time-scales and resource consumption. Herein, we describe a multi-channel microdroplet chip, which allows fast and directed dispensing of reactants into individual droplets in a segmented flow. This gives access to study the reaction progress in situ via surface-enhanced Raman spectroscopic monitoring of fast moving individual droplets. This opens up new avenues for high-throughput screening of organic reactions at the micro- and nano-scale.
authors.affiliation: Institut für Analytische Chemie, Universität Leipzig, Linnéstr. 3, D-04103 Leipzig, Germany. belder@uni-leipzig.de.
authors.forename: T-A
authors.initials: TA
authors.lastname: Meier
authors.forename: R J
authors.initials: RJ
authors.lastname: Beulig
authors.forename: E
authors.initials: E
authors.lastname: Klinge
authors.forename: M
authors.initials: M
authors.lastname: Fuss
authors.forename: S
authors.initials: S
authors.lastname: Ohla
authors.forename: D
authors.initials: D
authors.lastname: Belder