title: Topographic and biomechanical evaluation of corneas in patients with ocular rosacea.
abstract: OBJECTIVE
  To compare the topographic and biomechanical properties of corneas in the eyes of patients with ocular rosacea (OR) with those of healthy individuals.
  
  
  METHODS
  Thirty-four healthy individuals (control group) and 34 patients with OR (study group) were evaluated in this study. Topographic measurements including keratometry values, irregularity, and surface asymmetry index in the right eye of each participant were obtained using a Scheimpflug camera with a Placido disc topographer (Sirius). Corneal hysteresis (CH), corneal resistance factor (CRF), corneal-compensated intraocular pressure (IOP), and Goldmann-related IOP were measured using the Reichert Ocular Response Analyzer. Central corneal thickness was also measured using ultrasonic pachymetry and the Sirius corneal topography system.
  
  
  RESULTS
  Topographic parameters were not significantly different between the groups (P > 0.05). Mean CH and CRF were significantly lower in patients with OR (P = 0.003 and 0.001, respectively). Central corneal thickness was significantly lower in patients with OR compared with healthy controls (P < 0.001). Mean Goldmann-related IOP and corneal-compensated IOP were not significantly different between the groups (P = 0.09 and 0.13, respectively).
  
  
  CONCLUSIONS
  This study demonstrated that although the eyes of patients with OR had corneal topographic findings similar to those of healthy controls, corneal biomechanical measurements (CH and CRF) were significantly lower in patients with OR. These results need to be considered when planning corneal refractive surgery in patients with OR.
authors.affiliation: *Department of Ophthalmology, Beyoglu Eye Research and Education Hospital, Istanbul, Turkey; †Department of Ophthalmology, Istanbul Medeniyet University, Goztepe Education and Research Hospital, Istanbul, Turkey; and ‡Department of Dermatology, Istanbul University, Cerrahpasa Faculty of Medicine, Istanbul, Turkey.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Yildirim
authors.forename: Onur
authors.initials: O
authors.lastname: Olcucu
authors.forename: Alper
authors.initials: A
authors.lastname: Agca
authors.forename: Yalcin
authors.initials: Y
authors.lastname: Karakucuk
authors.forename: Nese
authors.initials: N
authors.lastname: Alagoz
authors.forename: Cagri
authors.initials: C
authors.lastname: Mutaf
authors.forename: Ahmet
authors.initials: A
authors.lastname: Demirok
authors.forename: Zekayi
authors.initials: Z
authors.lastname: Kutlubay
mesh_terms: D000293:Adolescent; D000328:Adult; D001696:Biomechanical Phenomena; D016022:Case-Control Studies; D003315:Cornea / Q000503:physiopathology*; D003316:Corneal Diseases / Q000209:etiology / Q000503:physiopathology*; D019781:Corneal Topography; D004548:Elasticity; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D011446:Prospective Studies; D012393:Rosacea / Q000503:physiopathology*; D014065:Tonometry, Ocular; D055815:Young Adult