title: Magnetic nanoparticles as potential candidates for biomedical and biological applications.
abstract: Magnetic iron oxide nanoparticles have become the main candidates for biomedical and biological applications, and the application of small iron oxide nanoparticles in in vitro diagnostics has been practiced for about half a century. Magnetic nanoparticles (MNPs), in combination with an external magnetic field and/or magnetizable grafts, allow the delivery of particles to the chosen target area, fix them at the local site while the medication is released, and act locally. In this review, we focus mostly on the potential use of MNPs for biomedical and biotechnological applications, and the improvements made in using these nanoparticles (NPs) in biological applications.
authors.affiliation: a Drug Applied Research Center, Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Zeinali Sehrig
authors.affiliation: b Biotechnology Research Center, Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Sima
authors.initials: S
authors.lastname: Majidi
authors.affiliation: a Drug Applied Research Center, Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Nasrin
authors.initials: N
authors.lastname: Nikzamir
authors.affiliation: a Drug Applied Research Center, Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Nasim
authors.initials: N
authors.lastname: Nikzamir
authors.affiliation: a Drug Applied Research Center, Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Nikzamir
authors.affiliation: a Drug Applied Research Center, Tabriz University of Medical Sciences , Tabriz , Iran.|b Biotechnology Research Center, Tabriz University of Medical Sciences , Tabriz , Iran.|c Hematology and Oncology Research Center, Tabriz University of Medical Sciences , Tabriz , Iran.|d Department of Medical Nanotechnology , Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Abolfazl
authors.initials: A
authors.lastname: Akbarzadeh
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D058185:Magnetite Nanoparticles / Q000737:chemistry*
chemical_list: D058185:Magnetite Nanoparticles
keywords: biotechnological applications; diagnostics; iron oxide nanoparticles; target