title: [The correlation between plasma calprotectin and neutrophil count in patients with aggressive periodontitis].
abstract: OBJECTIVE
  To measure the levels of plasma calprotectin in aggressive periodontitis (AgP) patients and to analyze the relationship between the plasma calprotectin and neutrophil count.
  
  
  METHODS
  Venous blood samples were collected from 61 AgP patients and 48 periodontally healthy controls. Clinical examination consisted of bleeding index (BI), probing depth (PD), attachment loss measurements (AL) and percentage of severe sites. Plasma level of calprotectin was determined by enzyme-linked immunosorbent assay.
  
  
  RESULTS
  The plasma concentrations of calprotectin in AgP patients [(2.1±1.1) mg/L] were significantly higher than those in healthy controls[(1.5±0.6) mg/L] (P < 0.01). The plasma concentration of calprotectin in AgP patients was positively correlated with BI (r = 0. 271, P = 0.035), PD (r = 0.437, P = 0.000), AL (r = 0.450, P = 0.000) and percentage of severe sites (r = 0.423, P = 0.001). While the neutrophil count was also positively correlated with the plasma concentrations of calprotectin in AgP patients (r = 0.380, P = 0.004).
  
  
  CONCLUSIONS
  AgP may have impact on the elevation of plasma level of calprotectin.
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Sun
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China. Email: kqhxmeng@126.com.
authors.forename: Huanxin
authors.initials: H
authors.lastname: Meng
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Dong
authors.initials: D
authors.lastname: Shi
authors.affiliation: Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Zhibin
authors.initials: Z
authors.lastname: Chen
mesh_terms: D010520:Aggressive Periodontitis / Q000097:blood / Q000276:immunology*; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007958:Leukocyte Count; D039841:Leukocyte L1 Antigen Complex / Q000097:blood*; D009504:Neutrophils; D010949:Plasma
chemical_list: D039841:Leukocyte L1 Antigen Complex