title: Nasal isolation of Mannheimia haemolytica and Pasteurella multocida as predictors of respiratory disease in shipped calves.
abstract: Three hundred ninety five calves were purchased from sale barns and delivered to the Willard Sparks Beef Research Center. Nasal swabs were collected to determine if presence of Mannheimia haemolytica and Pasteurella multocida in the upper respiratory tract (URT) can facilitate diagnosis of bovine respiratory disease (BRD). Samples were collected at arrival and at treatment for BRD. Clinically healthy control calves were sampled at time of treatment of sick calves. M. haemolytica was more commonly isolated from calves at treatment than at time of arrival or from control calves. M. haemolytica was more common in calves requiring treatment than in those never treated. Need for treatment and number of treatments were negatively associated with average daily gain, supporting the accuracy of diagnosis. These results suggest that URT sampling, when combined with clinical diagnosis, may assist in providing greater diagnostic accuracy, improving ability to evaluate risk factors, interventions, and treatments.
authors.affiliation: Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078-2007, USA. Electronic address: jared.d.taylor@okstate.edu.
authors.forename: J D
authors.initials: JD
authors.lastname: Taylor
authors.affiliation: Department of Animal Science, Oklahoma State University, Stillwater, OK 74078-2007, USA.
authors.forename: B P
authors.initials: BP
authors.lastname: Holland
authors.affiliation: Department of Veterinary Clinical Sciences, Oklahoma State University, Stillwater, OK 74078-2007, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Step
authors.affiliation: Department of Statistics, Oklahoma State University, Stillwater, OK 74078-2007, USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Payton
authors.affiliation: Department of Veterinary Pathobiology, Oklahoma State University, Stillwater, OK 74078-2007, USA.
authors.forename: A W
authors.initials: AW
authors.lastname: Confer
mesh_terms: D000818:Animals; D048090:Bovine Respiratory Disease Complex / Q000175:diagnosis* / Q000382:microbiology*; D002417:Cattle; D016978:Mannheimia haemolytica / Q000302:isolation & purification*; D009666:Nose / Q000382:microbiology; D016979:Pasteurella multocida / Q000302:isolation & purification*; D011237:Predictive Value of Tests
keywords: BRD; Bovine respiratory disease; Mannheimia haemolytica