title: Metal-free, efficient hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate in neutral media.
abstract: The first example of metal-free regioselective hydrazination of imidazo[1,2-a]pyridine with diethyl azodicarboxylate is accomplished. This procedure is chemically appealing due to the high degree of functional group tolerance and efficiency in expanding the molecular diversity.
authors.affiliation: Department of Pharmacology and Toxicology, College of Pharmacy, The University of Arizona, Tucson, Arizona 85721, USA. hongyuli@pharmacy.arizoan.edu.
authors.forename: Yuanxiang
authors.initials: Y
authors.lastname: Wang
authors.forename: Brendan
authors.initials: B
authors.lastname: Frett
authors.forename: Nick
authors.initials: N
authors.lastname: McConnell
authors.forename: Hong-Yu
authors.initials: HY
authors.lastname: Li
mesh_terms: D002244:Carbon / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry*; D015195:Drug Design; D006834:Hydrazines / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry*; D007700:Kinetics; D008670:Metals / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry
chemical_list: D002264:Carboxylic Acids; D006834:Hydrazines; D007093:Imidazoles; D008670:Metals; D011725:Pyridines; D012997:Solvents; C029424:hydrazine; D002244:Carbon; C001439:imidazo(1,2-a)pyridine