title: [Ischaemic colitis after loperamide treatment].
abstract: Ischaemic colitis is a potentially mortal illness which usually arises from decreased mesenteric blood flow. Loperamide is used in the treatment of both acute and chronic diarrhoea. We present a case of a 62-year-old man with no history of abdominal illness who was admitted with a distended and sore abdomen. Ten days prior to admission he was treated with loperamide. Because of his severe condition he had an emergency laparotomy which showed a necrotic colon and terminal ileum - both were resected. No thromboembolic cause was found and we therefore suggest loperamide as an inducing factor.
authors.affiliation: Lindesnæsvej 1, 8200 Aarhus N. bakgulstad@youmail.com.
authors.forename: Mikkel Bak
authors.initials: MB
authors.lastname: Gulstad
authors.forename: Henrik
authors.initials: H
authors.lastname: Thomsen
mesh_terms: D000930:Antidiarrheals / Q000009:adverse effects* / Q000627:therapeutic use; D017091:Colitis, Ischemic / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D003967:Diarrhea / Q000188:drug therapy; D006801:Humans; D008139:Loperamide / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
chemical_list: D000930:Antidiarrheals; D008139:Loperamide