title: Recognizing and managing comorbidities in psoriatic arthritis.
abstract: OBJECTIVE
  Many patients with psoriatic arthritis (PsA) have additional medical problems that can have an impact on morbidity and mortality. The goal of this review is to summarize the available evidence to date on the association of medical comorbidities with PsA and the implications these comorbidities have on prognosis, therapy selection and treatment response.
  
  
  RESULTS
  Cardiovascular disease, metabolic syndrome, obesity, diabetes, fatty liver disease Crohn's disease, ophthalmic disease, depression and anxiety are common comorbidities associated with PsA. Additional comorbidities may include an elevated risk for malignancy and osteoporosis; however, fewer studies have addressed these issues and the data available are sometimes conflicting.
  
  
  CONCLUSIONS
  All clinicians caring for patients with PsA should be aware of the relevant comorbidities affecting patients with PsA and should have an understanding of how these comorbidities affect management.
authors.affiliation: aDivision of Rheumatology, Center for Clinical Epidemiology and Biostatistics, Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania bHospital for Special Surgery, New York cRheumatologic and Immunologic Disease, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Alexis
authors.initials: A
authors.lastname: Ogdie
authors.forename: Sergio
authors.initials: S
authors.lastname: Schwartzman
authors.forename: M Elaine
authors.initials: ME
authors.lastname: Husni
mesh_terms: D015535:Arthritis, Psoriatic / Q000188:drug therapy / Q000453:epidemiology*; D002318:Cardiovascular Diseases / Q000453:epidemiology; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D005128:Eye Diseases / Q000453:epidemiology; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000453:epidemiology; D007674:Kidney Diseases / Q000453:epidemiology; D008107:Liver Diseases / Q000453:epidemiology; D001523:Mental Disorders / Q000453:epidemiology; D009369:Neoplasms / Q000453:epidemiology; D009765:Obesity / Q000453:epidemiology; D010024:Osteoporosis / Q000453:epidemiology