title: [A case of multiple liver metastases from colon cancer treated with complete resection via two-stage hepatectomy after regeneration of the liver].
abstract: A 55-year-old woman underwent low anterior resection for sigmoid colon cancer with multiple bilobar metastases. She then received 23 courses of Leucovorin, fluorouracil, and oxaliplatin (mFOLFOX) plus bevacizumab and 13 courses of Leucovorin, fluorouracil, and irinotecan (FOLFIRI) plus bevacizumab as down staging chemotherapy. A two-stage hepatectomy was planned to avoid the risk of hepatic failure due to radial resection of bilobar metastases. Therefore, a right lobectomy was performed, and curative resection was achieved 54 days after the first hepatectomy. Two-stage hepatectomy as well as a combination of induction chemotherapy and portal vein embolization may have contributed to the improved prognosis of the initially unresectable multiple bilobar liver metastases.
authors.affiliation: Dept. of Surgery, Toshima Hospital.
authors.forename: Toshiya
authors.initials: T
authors.lastname: Sugishita
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ganno
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Hataji
authors.forename: Katunori
authors.initials: K
authors.lastname: Ami
authors.forename: Takeo
authors.initials: T
authors.lastname: Nagahama
authors.forename: Akira
authors.initials: A
authors.lastname: Fukuda
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ando
authors.forename: Kuniyoshi
authors.initials: K
authors.lastname: Arai
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000502:physiology*; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary / Q000601:surgery*; D008875:Middle Aged; D012038:Regeneration; D012811:Sigmoid Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery