title: Effects of feminine cleanser Inclear on sperm motility: A prospective study.
abstract: OBJECTIVE
  The objective of this study is to estimate the effects of Inclear, a feminine cleanser, on sperm motility.
  
  
  METHODS
  Semen samples were obtained from infertile male patients. Following liquefaction, the raw semen samples were diluted with Ham's F-10 nutrient mixture medium containing 0.4% human serum albumin solution at a ratio of 1:3. The semen samples were subsequently centrifuged to separate the seminal plasma from the serum. The supernatant was discarded, and the pellet was resuspended. The sample was again centrifuged to remove cell debris, and the supernatant was removed. The final pellet was gently loosened by resuspension and incubated in medium alone as a control, and in a 10% solution of the medium plus Inclear. A sampling time of 30 minutes was selected on the basis of sperm transport studies. Sperm motility was evaluated with computer-assisted sperm analysis.
  
  
  RESULTS
  A total of 20 samples were analyzed. The mean age of patients was 34.40±2.96 years. There was no difference in sperm concentration and motility in the two samples at 0 minute and 30 minutes of incubation. In both semen samples, the sperm concentration and motility decreased after an incubation period of 30 minutes. However, there was no statistical difference between the samples. Sperm concentration and motility were not significantly different between the control and Inclear samples after 0 minute and 30 minutes of incubation.
  
  
  CONCLUSIONS
  Inclear has no negative effects on sperm motility. This product can be recommended to pregnancy planners for vaginal hygiene and as a vaginal lubricant.
authors.affiliation: Laboratory of Reproductive Medicine, Cheil General Hospital and Women's Healthcare Center, Catholic Kwandong University College of Medicine, Seoul, Korea.
authors.forename: Dong-Wook
authors.initials: DW
authors.lastname: Park
authors.affiliation: Laboratory of Reproductive Medicine, Cheil General Hospital and Women's Healthcare Center, Catholic Kwandong University College of Medicine, Seoul, Korea.
authors.forename: Jin Hee
authors.initials: JH
authors.lastname: An
authors.affiliation: Laboratory of Reproductive Medicine, Cheil General Hospital and Women's Healthcare Center, Catholic Kwandong University College of Medicine, Seoul, Korea.
authors.forename: Sang Chul
authors.initials: SC
authors.lastname: Han
authors.affiliation: WeTTrust Korea Co., Ltd., Seongnam, Korea.
authors.forename: Jongwon
authors.initials: J
authors.lastname: Lee
authors.affiliation: Department of Urology, Cheil General Hospital and Women's Healthcare Center, Catholic Kwandong University College of Medicine, Seoul, Korea.
authors.forename: Hyo Serk
authors.initials: HS
authors.lastname: Lee
authors.affiliation: Department of Urology, Cheil General Hospital and Women's Healthcare Center, Catholic Kwandong University College of Medicine, Seoul, Korea.
authors.forename: Ju Tae
authors.initials: JT
authors.lastname: Seo
keywords: Feminine hygiene products; Lubricants; Sperm motility