title: An electrochemical peptide cleavage-based biosensor for prostate specific antigen detection via host-guest interaction between ferrocene and β-cyclodextrin.
abstract: Here we have developed a "signal-on" peptide cleavage-based assay to directly transduce the peptide cleavage events into electrochemical signals via the host-guest interaction between ferrocene (Fc) and β-cyclodextrin (β-CD) for prostate specific antigen (PSA) detection.
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry, Ministry of Education (Southwest University), College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China. yuanruo@swu.edu.cn.
authors.forename: Shunbi
authors.initials: S
authors.lastname: Xie
authors.forename: Jin
authors.initials: J
authors.lastname: Zhang
authors.forename: Yali
authors.initials: Y
authors.lastname: Yuan
authors.forename: Yaqin
authors.initials: Y
authors.lastname: Chai
authors.forename: Ruo
authors.initials: R
authors.lastname: Yuan
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D004563:Electrochemistry; D005296:Ferrous Compounds / Q000737:chemistry*; D006801:Humans; D000075163:Metallocenes; D010455:Peptides / Q000737:chemistry*; D017430:Prostate-Specific Antigen / Q000032:analysis*; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D005296:Ferrous Compounds; D000075163:Metallocenes; D010455:Peptides; D047392:beta-Cyclodextrins; D017430:Prostate-Specific Antigen; C031215:betadex; C004998:ferrocene