title: Fulminant intraoperative right heart and pulmonary artery thrombosis following prothrombin complex concentrate infusion after complex open heart surgery with cardiopulmonary bypass.
abstract: Prothrombin complex concentrates are increasingly used during complex cardiac surgery with cardiopulmonary bypass. Reports describing massive thromboembolism after administration of prothrombin complex concentrates are rare. We report a case of a patient developing massive intracardiac and pulmonary artery thrombus formations during infusion of a moderate dose of prothrombin complex concentrate after separation from cardiopulmonary bypass for complex open heart surgery.
authors.affiliation: From the Institute of Anesthesiology and Department for Surgery of Congenital Heart Disease, Heart and Diabetes Center North Rhine-Westphalia, Ruhr-University Bochum, Bad Oeynhausen, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Koster
authors.forename: Ties
authors.initials: T
authors.lastname: Meyer-Jark
authors.forename: Uwe
authors.initials: U
authors.lastname: Schirmer
authors.forename: Eugene
authors.initials: E
authors.lastname: Sandica