title: Clinical evaluation of the OneStep Gonorrhea RapiCard InstaTest for detection of Neisseria gonorrhoeae in symptomatic patients from KwaZulu-Natal, South Africa.
abstract: We evaluated a point-of-care test for the detection of Neisseria gonorrhoeae in patients attending a public health clinic in KwaZulu-Natal, South Africa. The test showed a low sensitivity against PCR and culture (<40%); however, a higher specificity was observed (>95%). This test is unsuitable as a screening tool for gonorrhea.
authors.affiliation: HIV Prevention Research Unit, Medical Research Council, Westville, Durban, South Africa Nathlee.abbai@mrc.ac.za.
authors.forename: N S
authors.identifier: http://orcid.org/0000-0003-2392-0574
authors.initials: NS
authors.lastname: Abbai
authors.affiliation: Infectious Diseases, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa Infection Prevention and Control, KwaZulu-Natal Department of Health, Durban, South Africa.
authors.forename: P
authors.initials: P
authors.lastname: Moodley
authors.affiliation: Biostatistics Unit, Medical Research Council, Durban, South Africa.
authors.forename: T
authors.initials: T
authors.lastname: Reddy
authors.affiliation: HIV Prevention Research Unit, Medical Research Council, Westville, Durban, South Africa.
authors.forename: T G
authors.initials: TG
authors.lastname: Zondi
authors.affiliation: Infectious Diseases, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: S
authors.initials: S
authors.lastname: Rambaran
authors.affiliation: Infectious Diseases, School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: K
authors.initials: K
authors.lastname: Naidoo
authors.affiliation: HIV Prevention Research Unit, Medical Research Council, Westville, Durban, South Africa Department of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, United Kingdom.
authors.forename: G
authors.initials: G
authors.lastname: Ramjee
mesh_terms: D000942:Antigens, Bacterial / Q000302:isolation & purification; D001431:Bacteriological Techniques; D005260:Female; D006069:Gonorrhea / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D008297:Male; D009344:Neisseria gonorrhoeae / Q000302:isolation & purification*; D019095:Point-of-Care Systems; D011933:Reagent Kits, Diagnostic; D013019:South Africa / Q000453:epidemiology
chemical_list: D000942:Antigens, Bacterial; D011933:Reagent Kits, Diagnostic