title: Sensorineural hearing loss in hemorrhagic dengue?
abstract: BACKGROUND
  Dengue is an acute febrile infectious disease, with high fever followed by symptoms flu-like. Dengue hemorrhagic fever (DHF) is a vascular leak syndrome and could present spontaneous bleeding and worsening of symptoms after some days. Dengue could have some ENT manifestations, however hearing loss is not one of them. Sudden hearing loss is considered as sensorineural or perceptual hearing loss with a sudden onset in a person without other prior otological history. The relation between infectious diseases and sudden hearing are been investigated, some viruses were already linked, but the relation between dengue virus and sudden hearing still remains unknown. This article has the goal of presenting a case of DHF that evolved with SSHL in his hospitalization process.
  
  
  METHODS
  We report a 60 years-male patient of with DHF who developed bilateral secretory otitis media and sensorineural hearing loss after the fifth day of onset of symptoms. His hearing loss remained even after 7 months and the patient was referred for hearing aid fitting.
  
  
  CONCLUSIONS
  This is the first case report that brings together DHF and sudden hearing loss. In the development of this case no other cause to sudden hearing loss was found and the correlation between dengue and hearing loss was questioned. In the literature review was found that some viruses, as mumps virus, varicella-zoster virus and HSV-1 and HSV-2 are related to sudden hearing loss, all of them fit in the viral theory. Besides the viral theory of sudden hearing loss, there is the vascular theory that is the occlusion of the end artery that supplies the cochlea. DHF has a vascular commitment, and the hypothesis of a vascular cause could be elicited in this case. Many studies in this area are needed and this article has the objective of elicit the discussion about the subject. Could dengue be associated with sensorineural hearing loss?
authors.affiliation: Faculty of Medical Sciences of Santa Casa, São Paulo, Brazil (FCMSCSP), Brazil. Electronic address: bruninhatalia@gmail.com.
authors.forename: Bruna Natália Freire
authors.initials: BN
authors.lastname: Ribeiro
authors.affiliation: UNICAMP, Brazil. Electronic address: alecgxl2@hotmail.com.
authors.forename: Alexandre Caixeta
authors.initials: AC
authors.lastname: Guimarães
authors.affiliation: Faculty of Medical Sciences of Santa Casa, São Paulo, Brazil (FCMSCSP), Brazil. Electronic address: felipeyazawa@gmail.com.
authors.forename: Felipe
authors.initials: F
authors.lastname: Yazawa
authors.affiliation: Faculty of Medical Sciences of Santa Casa, São Paulo, Brazil (FCMSCSP), Brazil. Electronic address: tammymessias@gmail.com.
authors.forename: Tammy Fumiko Messias
authors.initials: TF
authors.lastname: Takara
authors.affiliation: UNICAMP, Brazil. Electronic address: guimachadocarvalho@gmail.com.
authors.forename: Guilherme Machado
authors.initials: GM
authors.lastname: de Carvalho
authors.affiliation: UNICAMP, Brazil. Electronic address: czappelini2@hotmail.com.
authors.forename: Carlos Eduardo Monteiro
authors.initials: CE
authors.lastname: Zappelini
keywords: Dengue; Hearing loss; Sensorineural deafness