title: The CXC chemokine receptors of fish: Insights into CXCR evolution in the vertebrates.
abstract: This article will review current knowledge on CXCR in fish, that represent three distinct vertebrate groups: Agnatha (jawless fishes), Chondrichthyes (cartilaginous fishes) and Osteichthyes (bony fishes). With the sequencing of many fish genomes, information on CXCR in these species in particular has expanded considerably. In mammals, 6 CXCRs have been described, and their homologues will be initially reviewed before considering a number of atypical CXCRs and a discussion of CXCR evolution.
authors.affiliation: Scottish Fish Immunology Research Centre, University of Aberdeen, Aberdeen AB24 2TZ, UK; School of Biological Sciences, University of Aberdeen, Aberdeen AB24 2TZ, UK. Electronic address: j.j.zou@abdn.ac.uk.
authors.forename: Jun
authors.initials: J
authors.lastname: Zou
authors.affiliation: School of Biological Sciences, University of Aberdeen, Aberdeen AB24 2TZ, UK; Centre for Genome-Enabled Biology and Medicine, University of Aberdeen, Aberdeen AB24 2TZ, UK.
authors.forename: Anthony K
authors.initials: AK
authors.lastname: Redmond
authors.affiliation: Scottish Fish Immunology Research Centre, University of Aberdeen, Aberdeen AB24 2TZ, UK; Key Laboratory of Aquaculture and Ecology of Coastal Pools of Jiangsu Province, Department of Ocean Technology, Yancheng Institute of Technology, Yancheng, Jiangsu 224051, China.
authors.forename: Zhitao
authors.initials: Z
authors.lastname: Qi
authors.affiliation: School of Biological Sciences, University of Aberdeen, Aberdeen AB24 2TZ, UK.
authors.forename: Helen
authors.initials: H
authors.lastname: Dooley
authors.affiliation: Scottish Fish Immunology Research Centre, University of Aberdeen, Aberdeen AB24 2TZ, UK; School of Biological Sciences, University of Aberdeen, Aberdeen AB24 2TZ, UK.
authors.forename: Chris J
authors.initials: CJ
authors.lastname: Secombes
mesh_terms: D000818:Animals; D005075:Biological Evolution; D005399:Fishes / Q000235:genetics*; D054387:Receptors, CXCR / Q000235:genetics*; D014714:Vertebrates / Q000235:genetics*
chemical_list: D054387:Receptors, CXCR
keywords: CXC chemokine receptors; Evolution; Fish; Vertebrates