title: The role of hemodynamic catheterization in the evaluation of hypertrophic obstructive cardiomyopathy: A case series.
abstract: Confirmation of the presence and magnitude of left ventricular outflow tract (LVOT) obstruction is a critical component of the evaluation of symptoms in patients with hypertrophic cardiomyopathy (HCM). The presence of LVOT obstruction in patients with severe symptoms refractory to pharmacologic therapy identifies a subgroup of HCM patients who may benefit from septal reduction therapy. Two-dimensional echocardiography with continuous wave Doppler is the main tool for confirming the presence and severity of LVOT obstruction in HCM. However, when uncertainty remains following non-invasive evaluation, invasive hemodynamics studies are required to confirm and quantify LVOT obstruction. In this manuscript we describe a series of 6 cases in which hemodynamic catheterization is instrumental in supplementing non-invasive imaging in the assessment of LVOT obstruction in HCM.
authors.affiliation: Division of Cardiology, University of Colorado School of Medicine, Aurora, Colorado.
authors.forename: Kalkidan
authors.initials: K
authors.lastname: Bishu
authors.affiliation: Section of Cardiology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
authors.forename: Megan
authors.initials: M
authors.lastname: Coylewright
authors.affiliation: Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
authors.forename: Rick
authors.initials: R
authors.lastname: Nishimura
mesh_terms: D000368:Aged; D006328:Cardiac Catheterization; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D015150:Echocardiography, Doppler; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D020127:Recovery of Function; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014694:Ventricular Outflow Obstruction / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy
keywords: cardiomyopathy; catheterization; diagnostic; hemodynamics; hypertrophic; transeptal