title: Photocontrolled chignolin-derived β-hairpin peptidomimetics.
abstract: The synthesis of novel, chignolin-derived peptides comprising the azobenzene photoswitch [3-(3-aminomethyl)phenylazo]phenylacetic acid (AMPP) is reported. Reversible photoswitching behavior led to folding into β-hairpin-like structures, as unequivocally demonstrated by CD, FT-IR and NMR spectroscopy.
authors.affiliation: Department of Organic Chemistry, Faculty of Chemistry and Pharmacy, Ludwig-Maximilians-University LMU, 81377 Munich, Germany. anja.hoffmann-roeder@cup.lmu.de.
authors.forename: T
authors.initials: T
authors.lastname: Podewin
authors.forename: M S
authors.initials: MS
authors.lastname: Rampp
authors.forename: I
authors.initials: I
authors.lastname: Turkanovic
authors.forename: K L
authors.initials: KL
authors.lastname: Karaghiosoff
authors.forename: W
authors.initials: W
authors.lastname: Zinth
authors.forename: A
authors.initials: A
authors.lastname: Hoffmann-Röder
mesh_terms: D019342:Acetic Acid / Q000737:chemistry; D000595:Amino Acid Sequence; D009842:Oligopeptides / Q000737:chemistry*; D057786:Peptidomimetics / Q000737:chemistry*; D055668:Photochemical Processes; D017433:Protein Structure, Secondary
chemical_list: D009842:Oligopeptides; D057786:Peptidomimetics; C506175:chignolin; D019342:Acetic Acid