title: [Diagnostic value of (18)F-FDG PET/CT for solitary nodular-type bronchoalveolar carcinoma].
abstract: OBJECTIVE
  To assess the value of (18)F-FDG PET/CT in the diagnosis of solitary nodular-type bronchoalveolar carcinoma (BAC).
  
  
  METHODS
  The clinical and radiographic data were analyzed retrospectively in 30 patients with pathologically confirmed solitary nodular-type BAC who underwent (18)F-FDG PET/CT examinations between August, 2005 and December, 2006. The morphological and radioactive findings of the lesions were reviewed, and the maximum standard uptake values (SUVmax) were measured. The diagnostic accuracy of PET, PET/CT, and HRCT were analyzed.
  
  
  RESULTS
  The (18)F-FDG SUV was markedly lower in BAC than in other well differentiated adenocarcinoma. In 19 of the BAC cases, PET showed a SUVmax of no less than 2.5, demonstrating positive changes. Of the total of 30 cases, 5 had ground glass opacity (GGO) changes, 3 exhibited mixed nodules with GGO changes around the lesions, and 22 cases presented with solid nodules. HRCT showed that BAC located often in the superior lobes of the bilateral lungs, mostly below the pleura in the surrounding lung field; the lesions were patchy or nodular with irregular shapes, showing lobulation in 22 cases, spiculation in 15 cases, pleural indentation in 21 cases, and vacuolar changes in 4 cases. The diagnostic accuracy of PET, PET/CT and HRCT for solitary nodular-type BAC was 36.67%, 93.33%, and 93.33%, respectively.
  
  
  CONCLUSIONS
  The SUVmax of BAC provides only limited value for defining the nature of the lesions, but can serve as a general reference for assessing the disease activity. PET/CT, which allows both functional and imaging assessment, can be a valuable modality to reduce the misdiagnosis rate of BAC.
authors.affiliation: PET/CT Center, General Hospital of Guangzhou Command, Guangzhou 510010, China.E-mail: liuweikun@163.com.
authors.forename: Wei-Kun
authors.initials: WK
authors.lastname: Liu
authors.forename: Xiang-Dong
authors.initials: XD
authors.lastname: Li
authors.forename: Jiang-Tao
authors.initials: JT
authors.lastname: Quan
authors.forename: Xi
authors.initials: X
authors.lastname: Ouyang
authors.forename: Hui
authors.initials: H
authors.lastname: Zheng
mesh_terms: D002277:Carcinoma / Q000175:diagnosis*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis*; D049268:Positron-Emission Tomography; D012189:Retrospective Studies; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18