title: Evaluation of the Vitros Syphilis TPA chemiluminescence immunoassay as a first-line method for reverse syphilis screening.
abstract: We report here the results of the diagnostic performances of Vitros Syphilis TPA (a chemiluminescence treponemal assay) compared with those of two treponemal enzyme immunoassays and of traditional versus reverse syphilis algorithms. Ease of use, automation, and high throughput make the Vitros Syphilis TPA assay a good choice for syphilis screening in high-volume laboratories.
authors.affiliation: Centre for Epidemiological Studies on HIV/STI in Catalonia (CEEISCAT), Agencia de Salut Publica de Catalunya (ASPC), Generalitat de Catalunya, Badalona, Spain Department of Microbiology, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain.
authors.forename: Victoria
authors.initials: V
authors.lastname: González
authors.affiliation: Department of Microbiology, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain.
authors.forename: Gema
authors.initials: G
authors.lastname: Fernández
authors.affiliation: Laboratori Clínic de l'Hospitalet, Hospitalet de Llobregat, Barcelona, Spain.
authors.forename: Eva
authors.initials: E
authors.lastname: Dopico
authors.affiliation: Department of Microbiology, Hospital de la Santa Creu i Sant Pau, Universitat de Barcelona, Barcelona, Spain.
authors.forename: Nuria
authors.initials: N
authors.lastname: Margall
authors.affiliation: Department of Microbiology, Hospital Universitari Vall d'Hebró, Universitat de Barcelona, Barcelona, Spain.
authors.forename: Juliana
authors.initials: J
authors.lastname: Esperalba
authors.affiliation: Department of Microbiology, Hospital de la Santa Creu i Sant Pau, Universitat de Barcelona, Barcelona, Spain.
authors.forename: Carme
authors.initials: C
authors.lastname: Muñoz
authors.affiliation: Laboratori Clínic de l'Hospitalet, Hospitalet de Llobregat, Barcelona, Spain.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Castro
authors.affiliation: Department of Microbiology, Hospital Universitari Vall d'Hebró, Universitat de Barcelona, Barcelona, Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: Sulleiro
authors.affiliation: Department of Microbiology, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain lmatas.germanstrias@gencat.cat.
authors.forename: Lurdes
authors.initials: L
authors.lastname: Matas
mesh_terms: D005189:False Positive Reactions; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D008163:Luminescent Measurements / Q000379:methods*; D012680:Sensitivity and Specificity; D013587:Syphilis / Q000175:diagnosis*