title: Oral mucosa self-graft in a patient with invasive conjunctival melanoma: a case report.
abstract: Conjunctival melanoma is a rare tumor, while malignant melanoma of the uveal tract is the most common primary intraocular tumor in adults. The authors highlighted the case of a 68-year-old male patient presented in June 2011 in the Ophthalmology Clinic of the Emergency County Hospital of Craiova, Romania, accusing foreign body sensation and the appearance of a tumor in the lower fornix of his right eye. The patient was clinically and paraclinically investigated, and clinically diagnosed with de novo malignant melanoma. The tumor was surgically excised and the lower fornix reconstructed with oral mucosa self-graft. Histopathological diagnosis was de novo, invasive, ulcerated malignant melanoma of the conjunctiva. Ki-67 immunohistochemical staining was also performed. After surgery, the patient was sent to the Oncology Department for specific treatment. Despite the histological poor prognosis factors present in our patient, two years after surgery and chemotherapy, the patient had no clinical sign of local or distance recurrent disease. Continuous ophthalmologic and oncological surveillance is necessary.
authors.affiliation: Department of Physiological Sciences, University of Medicine and Pharmacy of Craiova, Romania; balasoiu.maria@yahoo.com.
authors.forename: Maria Rodica
authors.initials: MR
authors.lastname: Mănescu
authors.forename: Maria
authors.initials: M
authors.lastname: Bălăşoiu
authors.forename: Monica Mihaela
authors.initials: MM
authors.lastname: Crăiţoiu
authors.forename: Ştefania
authors.initials: Ş
authors.lastname: Crăiţoiu
authors.forename: Cristiana Eugenia
authors.initials: CE
authors.lastname: Simionescu
authors.forename: Veronica
authors.initials: V
authors.lastname: Sfredel
authors.forename: Sorin Nicolae
authors.initials: SN
authors.lastname: Dinescu
authors.forename: Mihaela
authors.initials: M
authors.lastname: Niculescu
authors.forename: Marian
authors.initials: M
authors.lastname: Burcea
authors.forename: Andrei Theodor
authors.initials: AT
authors.lastname: Bălăşoiu
authors.forename: Carmen Luminiţa
authors.initials: CL
authors.lastname: Mocanu
mesh_terms: D000368:Aged; D003230:Conjunctival Neoplasms / Q000473:pathology* / Q000628:therapy*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology*; D009061:Mouth Mucosa / Q000637:transplantation*; D009361:Neoplasm Invasiveness; D014182:Transplantation, Autologous