title: Incidence of late-onset ocular hypertension following uncomplicated pars plana vitrectomy in pseudophakic eyes.
abstract: OBJECTIVE
  To determine the incidence of late-onset ocular hypertension following uncomplicated vitrectomy in pseudophakic eyes with an open angle.
  
  
  METHODS
  A retrospective observational case series.
  
  
  METHODS
  Seven hundred and sixty-seven eyes of 767 patients that underwent vitrectomy combined with cataract surgery in 1 eye were studied. There were 383 men and 384 women. The indications for vitrectomy were: 308 eyes with rhegmatogenous retinal detachment, 202 eyes with epiretinal membrane, 169 eyes with macular hole, 44 eyes with vitreous hemorrhage, 16 eyes with subretinal hemorrhage, 15 eyes with vitreomacular traction syndrome, 12 eyes with vitreous opacity, and 1 eye with retinoschisis. Of these, 176 eyes underwent vitrectomy alone because of previous cataract surgery. Late-onset ocular hypertension was defined as an intraocular pressure (IOP) >21 mm Hg that developed more than 2 months postoperatively in at least 2 postoperative visits. An increase in the IOP >4 mm Hg over the preoperative IOP was necessary. Eyes with ocular hypertension, glaucoma (suspect), or a possibility of IOP elevation were excluded.
  
  
  RESULTS
  The mean age was 63 ± 11 years. The mean follow-up duration after vitrectomy was 47.8 ± 25.3 months. Thirty-two eyes (4.2%) developed late-onset ocular hypertension. The mean age was 60 ± 10 years. The mean interval between vitrectomy and development of ocular hypertension was 31.1 ± 26.0 months. There were no significant differences in the incidence of late-onset ocular hypertension and the vitreoretinal disease for vitrectomy, sex, or gauge of instruments for vitrectomy.
  
  
  CONCLUSIONS
  Long-term IOP monitoring is necessary after vitrectomy.
authors.affiliation: Nagata Eye Clinic, Nara, Japan. Electronic address: noritama0620@topaz.ocn.ne.jp.
authors.forename: Noriko
authors.initials: N
authors.lastname: Toyokawa
authors.affiliation: Nagata Eye Clinic, Nara, Japan.
authors.forename: Hideya
authors.initials: H
authors.lastname: Kimura
authors.affiliation: Nagata Eye Clinic, Nara, Japan.
authors.forename: Miyo
authors.initials: M
authors.lastname: Matsumura
authors.affiliation: Nagata Eye Clinic, Nara, Japan.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Kuroda
mesh_terms: D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology*; D011183:Postoperative Complications; D019591:Pseudophakia / Q000150:complications*; D012164:Retinal Diseases / Q000601:surgery; D012189:Retrospective Studies; D014821:Vitrectomy; D014823:Vitreous Hemorrhage / Q000601:surgery
chemical_list: D000959:Antihypertensive Agents