title: Octyl-2-cyanoacrylate adhesive for skin closure: eight years experience.
abstract: Cyanoacrylate skin adhesive is increasingly used to ensure and stabilize wound closures. One of the documented favorable effects of these glues is to limit the risk of a surgical site infection by physically isolating the wound.
  
  
  METHODS
  From January 2005 to January 2013, 900 patients requiring surgical treatment in the Structure of Plastic Surgery of the University of Sienna were enrolled for the study and divided in two groups; 450 patients treated with glue versus 450 controls.
  
  
  RESULTS
  The cohort of patients treated with glue had lower incidence of wound infection and wound dehiscence. Approximately 375 work-hours were economized.
  
  
  CONCLUSIONS
  Octyl-2-cyanoacrylate is a valuable aid for ensuring the success of surgery by reducing surgical site infections. The use of octyl-2-cyanoacrylate is easy, guarantying a major superficial protection without relevant contraindications and with evident saving of time and resources.
authors.affiliation: Unity of Plastic and Reconstructive Surgery, University of Study of Siena, Siena, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Grimaldi
authors.affiliation: Unity of Plastic and Reconstructive Surgery, University of Study of Siena, Siena, Italy robertocuomo@outlook.com.
authors.forename: Roberto
authors.initials: R
authors.lastname: Cuomo
authors.affiliation: Unity of Plastic and Reconstructive Surgery, University of Study of Siena, Siena, Italy.
authors.forename: Cesare
authors.initials: C
authors.lastname: Brandi
authors.affiliation: Unity of Plastic and Reconstructive Surgery, University of Study of Siena, Siena, Italy.
authors.forename: Gaia
authors.initials: G
authors.lastname: Botteri
authors.affiliation: Unity of Plastic and Reconstructive Surgery, University of Study of Siena, Siena, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Nisi
authors.affiliation: Unity of Plastic and Reconstructive Surgery, University of Study of Siena, Siena, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: D'Aniello
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003487:Cyanoacrylates / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D017792:Surgical Stapling / Q000009:adverse effects / Q000379:methods*; D013530:Surgical Wound Infection / Q000453:epidemiology; D014014:Tissue Adhesives / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate
keywords: Octyl-2-cyanoacrylate; glue; infections