title: Adenosine-induced transient asystole.
abstract: Cerebral aneurysms are an important health issue in the United States, and the mortality rate following aneurysm rupture, or SAH, remains high. The treatment of these aneurysms uses endovascular options which include coil placement, stent assistant coiling and, recently, flow diversion. However, microsurgical clipping remains an option in those aneurysms not suited for endovascular therapy. These are often the more complicated aneurysms such as in large, giant aneurysms or deep-seated aneurysms. Circumferential visualization of the aneurysm, parent vessels, branches, perforators, and other neurovascular structures is important to prevent residual aneurysms or strokes from vessel or perforator occlusion. Decompression of the aneurysm sac is often required and we believe that adenosine-induced transient asystole should be an important option for clipping of complex cerebral aneurysms.
authors.affiliation: Houston Methodist Hospital, Houston, Texas.
authors.forename: Gavin W
authors.initials: GW
authors.lastname: Britz
mesh_terms: D000241:Adenosine / Q000494:pharmacology*; D004621:Embolization, Therapeutic; D057510:Endovascular Procedures; D006323:Heart Arrest / Q000139:chemically induced*; D006801:Humans; D002532:Intracranial Aneurysm / Q000628:therapy*; D015607:Stents; D014665:Vasodilator Agents / Q000494:pharmacology*
chemical_list: D014665:Vasodilator Agents; D000241:Adenosine
keywords: adenosine; complex brain aneurysm; transient asystole