title: Multifaceted antitumor responses to activating anti-CD40 antibody therapy combined with immunomodulatory or targeted agents.
abstract: Therapeutic targeting of the CD40 pathway may be efficacious for cancer treatment. Accumulating evidence suggests synergistic and unique antitumor responses may be achieved using CD40-based therapies in combination with other immunomodulators or targeted agents.
authors.affiliation: Cancer and Inflammation Program; National Cancer Institute ; Frederick, MD USA.
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Weiss
authors.affiliation: Cancer and Inflammation Program; National Cancer Institute ; Frederick, MD USA.
authors.forename: Robert H
authors.initials: RH
authors.lastname: Wiltout
keywords: biomarkers; immunostimulation; immunotherapy; inflammation; targets; therapeutic antibodies