title: [Rituximab-induced interstitial pneumonitis: report of two cases and literature review].
abstract: We report two cases of rituximab (RTX)-induced interstitial pneumonia in two lymphoma patients receiving RTX treatment. Interstitial pneumonia was successfully managed in these two cases after a one-week-long intervention with corresponding treatments without affecting further treatment of the primary disease. RTX-induced interstitial pneumonia is characterized by a latent onset with an unclear pathological mechanism and absence of typical symptoms. High-resolution CT scan can provide valuable evidence for early diagnosis of RTX-induced interstitial pneumonia, which might be attributed partially to an increased susceptibility to P. jirovecii and fungal infection due to prolonged RTX treatment.
authors.affiliation: Huiqiao Department, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. pbh66@126.com
authors.forename: Bao-Hong
authors.initials: BH
authors.lastname: Ping
authors.forename: Chun-Yan
authors.initials: CY
authors.lastname: Yue
authors.forename: Yang-Min
authors.initials: YM
authors.lastname: Zhu
authors.forename: Ya
authors.initials: Y
authors.lastname: Gao
authors.forename: Bin
authors.initials: B
authors.lastname: Wu
authors.forename: Jia-Qiong
authors.initials: JQ
authors.lastname: Hong
mesh_terms: D058846:Antibodies, Monoclonal, Murine-Derived / Q000009:adverse effects*; D004198:Disease Susceptibility; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced*; D000069283:Rituximab; D014057:Tomography, X-Ray Computed
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D000069283:Rituximab