title: Correlation between mammograghic findings and clinical/ pathologic features in women with small invasive breast carcinomas.
abstract: BACKGROUND
  To study the relationship between mammographic findings and clinical/pathologic features in women with 1-15mm sized invasive breast cancer.
  
  
  METHODS
  We investigated a consecutive series of 134 cases diagnosed in Tianjin Medical University Cancer Institute and Hospital in 2007. Mammographic findings were classified into five groups as follows :1) stellate mass without calcification; 2) non-stellate mass without calcification; 3) intermediate suspicious calcification with or without associated mass; 4) higher probability malignant calcification with or without associated mass; 5) focal asymmetry/distortion without associated calcification. Associations between mammographic and clinical/pathological features (menopause status/family history/histologic grade/lymph node status and ER/PR/HER2 status) was analyzed through logistic regression and chi square tests.
  
  
  RESULTS
  Compared to the stellate mass without calcification group, higher probability malignant calcification patients were associated significantly with a positive lymph node status, always presenting in patients who were non-menopausal and with a family history of carcinoma.
  
  
  CONCLUSIONS
  Higher probability malignant calcifications with or without associated tumor masses are associated with clinical/pathologic features of poor prognosis.
authors.affiliation: Department of Breast Imaging, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin Medical University, Ministry of Education, Tianjin, China E-mail : liupeifang@tjmuch.com.
authors.forename: Jun-Nan
authors.initials: JN
authors.lastname: Li
authors.forename: Jing
authors.initials: J
authors.lastname: Xu
authors.forename: Ju
authors.initials: J
authors.lastname: Wang
authors.forename: Chun
authors.initials: C
authors.lastname: Qing
authors.forename: Yu-Mei
authors.initials: YM
authors.lastname: Zhao
authors.forename: Pei-Fang
authors.initials: PF
authors.lastname: Liu
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D002288:Adenocarcinoma, Mucinous / Q000000981:diagnostic imaging / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D002114:Calcinosis; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000473:pathology*; D018275:Carcinoma, Lobular / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology*; D008327:Mammography; D060787:Neoplasm Grading; D009361:Neoplasm Invasiveness; D011379:Prognosis