title: Short-course radiotherapy in elderly patients with early stage non-melanoma skin cancer: a phase II study.
abstract: OBJECTIVE
  To evaluate outcome of an accelerated radiotherapy (RT) regimen in elderly patients with an early stage non-melanoma skin cancer (NMSC).
  
  
  METHODS
  Total RT dose was 30 Gy in 5 Gy fractions in six consecutive days.
  
  
  RESULTS
  Thirty-one patients were enrolled. Fourteen were aged ≥80 years. Acute skin and observed late toxicity were exclusively of grade 1. Thirty patients showed a complete response (median follow-up 30 months). Two-year actuarial local control was 93.2%. The cosmetic result was mostly judged as good or excellent.
  
  
  CONCLUSIONS
  Short-course RT in elderly NMSC patients produces >90% local control of disease.
authors.affiliation: Radiotherapy Unit, Oncology Department,1.
authors.forename: Marica
authors.initials: M
authors.lastname: Ferro
authors.forename: Francesco
authors.initials: F
authors.lastname: Deodato
authors.forename: Gabriella
authors.initials: G
authors.lastname: Macchia
authors.forename: Stefano
authors.initials: S
authors.lastname: Gentileschi
authors.forename: Savino
authors.initials: S
authors.lastname: Cilla
authors.forename: Gabriella
authors.initials: G
authors.lastname: Torre
authors.forename: Gilbert D A
authors.initials: GD
authors.lastname: Padula
authors.forename: Marianna
authors.initials: M
authors.lastname: Nuzzo
authors.forename: Mariangela
authors.initials: M
authors.lastname: Massaccesi
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Valentini
authors.forename: Alessio G
authors.initials: AG
authors.lastname: Morganti
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D019583:Dose Fractionation, Radiation; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011878:Radiotherapy / Q000009:adverse effects*; D011879:Radiotherapy Dosage; D012878:Skin Neoplasms / Q000473:pathology / Q000532:radiotherapy*
keywords: Cancer in the elderly; Non-melanoma skin cancer; Radiation oncology