title: Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment.
abstract: OBJECTIVE
  The purpose of this amendment is to provide an updated clinical framework for the diagnosis and treatment of interstitial cystitis/bladder pain syndrome based upon data received since the publication of original guideline in 2011.
  
  
  METHODS
  A systematic literature review using the MEDLINE(®) database (search dates 1/1/83-7/22/09) was conducted to identify peer-reviewed publications relevant to the diagnosis and treatment of IC/BPS. This initial review yielded an evidence base of 86 treatment articles after application of inclusion/exclusion criteria. The AUA update literature review process, in which an additional systematic review is conducted periodically to maintain guideline currency with newly published relevant literature, was conducted in July 2013. This review identified an additional 31 articles, which were added to the evidence base of this Guideline.
  
  
  RESULTS
  Newly incorporated literature describing the treatment of IC/BPS was integrated into the Guideline with additional treatment information provided as Clinical Principles and Expert Opinions when insufficient evidence existed. The diagnostic portion of the Guideline remains unchanged from the original publication and is still based on Expert Opinions and Clinical Principles.
  
  
  CONCLUSIONS
  The management of IC/BPS continues to evolve as can be seen by an expanding literature on the topic. This document constitutes a clinical strategy and is not intended to be interpreted rigidly. The most effective approach for a particular patient is best determined by the individual clinician and patient. As the science relevant to IC/BPS evolves and improves, the strategies presented will require amendment to remain consistent with the highest standards of care.
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Philip M
authors.initials: PM
authors.lastname: Hanno
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Deborah
authors.initials: D
authors.lastname: Erickson
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Robert
authors.initials: R
authors.lastname: Moldwin
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Martha M
authors.initials: MM
authors.lastname: Faraday
mesh_terms: D018856:Cystitis, Interstitial / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans
keywords: cystitis; interstitial; lower urinary tract symptoms; pelvic pain; urinary bladder diseases; urodynamics