title: A web-based study of the relationship of duration of insulin pump infusion set use and fasting blood glucose level in adults with type 1 diabetes.
abstract: BACKGROUND
  To evaluate the impact of infusion set use duration on glycemic control, we conducted an Internet-based study using the T1D Exchange's online patient community, Glu ( myGlu.org ).
  
  
  METHODS
  For 14 days, 243 electronically consented adults with type 1 diabetes (T1D) entered online that day's fasting blood glucose (FBG) level, the prior day's total daily insulin (TDI) dose, and whether the infusion set was changed.
  
  
  RESULTS
  Mean duration of infusion set use was 3.0 days. Mean FBG level was higher with each successive day of infusion set use, increasing from 126 mg/dL on Day 1 to 133 mg/dL on Day 3 to 147 mg/dL on Day 5 (P<0.001). TDI dose did not vary with increased duration of infusion set use.
  
  
  CONCLUSIONS
  Internet-based data collection was used to rapidly conduct the study at low cost. The results indicate that FBG levels increase with each additional day of insulin pump infusion set use.
authors.affiliation: 1 Jaeb Center for Health Research , Tampa, Florida.
authors.forename: Alysa J
authors.initials: AJ
authors.lastname: Sampson Perrin
authors.forename: Russell C
authors.initials: RC
authors.lastname: Guzzetta
authors.forename: Kellee M
authors.initials: KM
authors.lastname: Miller
authors.forename: Nicole C
authors.initials: NC
authors.lastname: Foster
authors.forename: Anna
authors.initials: A
authors.lastname: Lee
authors.forename: Joyce M
authors.initials: JM
authors.lastname: Lee
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Block
authors.forename: Roy W
authors.initials: RW
authors.lastname: Beck
mesh_terms: D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D003625:Data Collection / Q000379:methods; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005215:Fasting / Q000097:blood*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D007328:Insulin / Q000008:administration & dosage*; D007332:Insulin Infusion Systems / Q000706:statistics & numerical data*; D020407:Internet; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires; D013997:Time Factors; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin