title: Fish genome manipulation and directional breeding.
abstract: Aquaculture is one of the fastest developing agricultural industries worldwide. One of the most important factors for sustainable aquaculture is the development of high performing culture strains. Genome manipulation offers a powerful method to achieve rapid and directional breeding in fish. We review the history of fish breeding methods based on classical genome manipulation, including polyploidy breeding and nuclear transfer. Then, we discuss the advances and applications of fish directional breeding based on transgenic technology and recently developed genome editing technologies. These methods offer increased efficiency, precision and predictability in genetic improvement over traditional methods.
authors.affiliation: State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, 430072, China.
authors.forename: Ding
authors.initials: D
authors.lastname: Ye
authors.forename: ZuoYan
authors.initials: Z
authors.lastname: Zhu
authors.forename: YongHua
authors.initials: Y
authors.lastname: Sun
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D001947:Breeding / Q000379:methods*; D005260:Female; D005399:Fishes / Q000235:genetics* / Q000254:growth & development; D005786:Gene Expression Regulation; D016678:Genome / Q000235:genetics*; D008297:Male; D053652:Nuclear Transfer Techniques; D011123:Polyploidy