title: Imaging of articular cartilage: current concepts.
abstract: Magnetic resonance imaging (MRI) is the gold standard method for non-invasive assessment of joint cartilage, providing information on the structure, morphology and molecular composition of this tissue. There are certain minimum requirements for a MRI study of cartilage tissue: machines with a high magnetic field (> 1.5 Tesla); the use of surface coils; and the use of T2-weighted, proton density-weighted fast-spin echo (T2 FSE-DP) and 3D fat-suppressed T1-weighted gradient echo (3D-FS T1W GRE) sequences. For better contrast between the different joint structures, MR arthography is a method that can highlight minimal fibrillation or fractures of the articular surface and allow evaluation of the integrity of the native cartilage-repair tissue interface. To assess the biochemical composition of cartilage and cartilage repair tissue, various techniques have been proposed for studying proteoglycans [dGEMRIC, T1rho mapping, sodium (23Na) imaging MRI, etc.], collagen, and water distribution [T2 mapping, "magnetisation transfer contrast", diffusion-weighted imaging (DWI), and so on]. Several MRI classifications have been proposed for evaluating the processes of joint degeneration (WORMS, BLOKS, ICRS) and post-surgical maturation of repair tissue (MOCART, 3D MOCART). In the future, isotropic 3D sequences set to improve image quality and facilitate the diagnosis of disorders of articular structures adjacent to cartilage.
authors.affiliation: Orthopaedics and Traumatology, Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Varese, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Ronga
authors.affiliation: Radiology Unit, Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy.
authors.forename: Gloria
authors.initials: G
authors.lastname: Angeretti
authors.affiliation: Orthopaedics and Traumatology, Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Varese, Italy.
authors.forename: Sergio
authors.initials: S
authors.lastname: Ferraro
authors.affiliation: Orthopaedics and Traumatology, Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Varese, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: DE Falco
authors.affiliation: Department of Radiology, University of Cagliari, Italy.
authors.forename: Eugenio A
authors.initials: EA
authors.lastname: Genovese
authors.affiliation: Orthopaedics and Traumatology, Department of Biotechnology and Life Sciences (DBSV), University of Insubria, Varese, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Cherubino
keywords: articular cartilage; cartilage repair; contrast; magnetic resonance imaging