title: Transition-metal-free intramolecular carbene aromatic substitution/Büchner reaction: synthesis of fluorenes and [6,5,7]benzo-fused rings.
abstract: Intramolecular aromatic substitution and Büchner reaction have been established as powerful methods for the construction of polycyclic compounds. These reactions are traditionally catalyzed by Rh(II) catalysts with α-diazocarbonyl compounds as the substrates. Herein a transition-metal-free intramolecular aromatic substitution/Büchner reaction is presented. These reactions use readily available N-tosylhydrazones as the diazo compound precursors and show wide substrate scope.
authors.affiliation: Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871 (China).
authors.forename: Zhenxing
authors.initials: Z
authors.lastname: Liu
authors.forename: Haocheng
authors.initials: H
authors.lastname: Tan
authors.forename: Long
authors.initials: L
authors.lastname: Wang
authors.forename: Tianren
authors.initials: T
authors.lastname: Fu
authors.forename: Ying
authors.initials: Y
authors.lastname: Xia
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jianbo
authors.initials: J
authors.lastname: Wang
keywords: Büchner reaction; aromatic substitution; carbenes; diazo compounds; fluorenes