title: Nasal Eosinophilic Angiocentric Fibrosis with Orbital Extension.
abstract: Eosinophilic angiocentric fibrosis (EAF) is an extremely rare, chronic, benign, idiopathic disorder that mostly affects the upper respiratory tract, particularly the nasal cavity, and features progressive submucosal perivascular fibrosis. To the best of our knowledge, only seven cases of EAF with orbital involvement have been reported. We report a case of sinonasal EAF with orbital extension that presented with left nasolacrimal duct obstruction. A 35-year-old man presented with left epiphora, proptosis, anterolateral globe displacement and nasal obstruction. Endoscopic sinus examination showed a firm, gritty, creamy, yellow, fibrous, adherent mass of maxillary sinus. Diagnosis was established with histopathological examination of excisional biopsy of the lesion. Although EAF is very rare, it should be considered in the differential diagnosis of lesions of upper airway tract, particularly the nasal cavity. Biopsy is necessary for diagnosis and treatment planning. Resecting of the involved tissues completely is essential for prevention of recurrence.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Shiraz University of Medical Sciences, Shiraz, Iran, rhinology_research@ssu.ac.ir.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Faramarzi
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Dadgarnia
authors.forename: Mansour
authors.initials: M
authors.lastname: Moghimi
authors.forename: Hadi
authors.initials: H
authors.lastname: Sharouny
authors.forename: Nasim
authors.initials: N
authors.lastname: Behniafard
mesh_terms: D000328:Adult; D004802:Eosinophilia / Q000473:pathology*; D005355:Fibrosis / Q000473:pathology; D006801:Humans; D008297:Male; D009668:Nose Diseases / Q000473:pathology*; D009915:Orbit / Q000473:pathology*