title: [Diagnostic value of cardiac magnetic resonance in patients with acute viral myocarditis].
abstract: OBJECTIVE
  To assess the diagnostic value of cardiac magnetic resonance (CMR) in patients with acute viral myocarditis.
  
  
  METHODS
  Thirty patients with suspected acute viral myocarditis admitted in first people's hospital of Shunde from June 2011 to June 2013 were included in this prospective study. The diagnostic sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of acute viral myocarditis were evaluated by clinical diagnosis. Diagnostic value among different scan methods and Lake Louise criteria were compared.
  
  
  RESULTS
  Acute viral myocarditis was diagnosed in 63.33% (19/30) patients.Values for sensitivity, specificity, PPV, NPV, and diagnostic accuracy within the overall cohort were 57.89%, 72.73%, 78.57%, 50.00%, 63.33%, respectively by edema imaging (ER).Values for sensitivity, specificity, PPV, NPV, and diagnostic accuracy within the overall cohort were 78.95%, 63.64%, 78.95%, 63.64%, 73.33%, respectively using global relative enhancement (gRE).Values for sensitivity, specificity, PPV, NPV, and diagnostic accuracy within the overall cohort were 78.95%, 54.55%, 75.00%, 60.00%, 70.00%, respectively using late gadolinium enhancement (LGE) criteria.Values for sensitivity, specificity, PPV, NPV, and diagnostic accuracy within the overall cohort were 84.21%, 81.82%, 88.89%, 75.00%, 83.33% using Lake Louise criteria. The sensitivity, specificity, PPV, NPV, and diagnostic accuracy using Lake Louise criteria were significantly higher than using ER, gRE, LGE alone(all P < 0.05).Specificity was higher using ER than using gRE and LGE (both P < 0.05). The sensitivity, NPV, and diagnostic accuracy were significantly higher using gRE than using ER (all P < 0.05) and was similar as using LGE (all P > 0.05).
  
  
  CONCLUSIONS
  Cardiac magnetic resonance is an excellent imaging modality for the diagnosis of acute viral myocarditis.
authors.affiliation: Department of Cardiology, First People's Hospital of Shunde, Foshan 528300, China.
authors.forename: Haichun
authors.initials: H
authors.lastname: Ouyang
authors.forename: Haixiong
authors.initials: H
authors.lastname: Chen
authors.forename: Yunzhao
authors.initials: Y
authors.lastname: Hu
authors.affiliation: Email: wuyanxian200@sohu.com.
authors.forename: Yanxian
authors.initials: Y
authors.lastname: Wu
authors.forename: Wensheng
authors.initials: W
authors.lastname: Li
authors.forename: Yuying
authors.initials: Y
authors.lastname: Chen
authors.forename: Yujian
authors.initials: Y
authors.lastname: Cen
mesh_terms: D000208:Acute Disease; D003287:Contrast Media; D005682:Gadolinium; D006321:Heart; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009205:Myocarditis / Q000175:diagnosis* / Q000821:virology*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D005682:Gadolinium