title: Some pharmacokinetics of sevoflurane in a child with severe lipodystrophy.
abstract: Lipodystrophies are acquired or inherited disorders characterized in part by the selective loss of adipose tissue and hypertriglyceridemia. The present case report of 2 sevoflurane anesthetics given to a child with such a disorder, before and after correction of severe hypertriglyceridemia, illustrates the considerable effects of increased serum lipids and decreased fat stores on the pharmacokinetics of sevoflurane.
authors.affiliation: From the Department of Anesthesiology, University Hospital Ghent, Ghent, Belgium.
authors.forename: Evi R
authors.initials: ER
authors.lastname: Steen
authors.forename: Luc E C
authors.initials: LE
authors.lastname: De Baerdemaeker
authors.forename: Jurgen
authors.initials: J
authors.lastname: Van Limmen
authors.forename: Patrick
authors.initials: P
authors.lastname: Wouters