title: Recommendations from the Italian Interdisciplinary Working Group (AIMN, AIP, SINDEM) for the utilization of amyloid imaging in clinical practice.
abstract: Positron emission tomography (PET) of brain amyloid is a technology that has been approved by Food and Drug Administration and European Medical Agency, but its clinical utility in medical practice requires careful definition. To provide guidance to italian dementia care practitioners, patients, and caregivers, a group of experts from "Associazione Italiana di Medicina Nucleare" (AIMN), "Associazione Italiana di Psicogeriatria" (AIP) and "Società Italiana per lo Studio delle Demenze" (SINDEM) convened the Italian Interdisciplinary Working Group on Amyloid Imaging. The Working Group considered a range of clinical scenarios in which amyloid PET should be recommended. Peer-reviewed, published literature was searched to ascertain available evidence relevant to these recommendations. Although empirical evidence of impact on clinical outcomes is not yet available, a set of specific recommended use criteria were agreed to define the types of patients and clinical circumstances in which amyloid PET could be used. Both correct and incorrect uses were considered and formulated. Because both dementia care and amyloid-PET technology are in active development, these recommendations will require periodic reassessment.
authors.affiliation: Nuclear Medicine, Fondazione Poliambulanza, Istituto Ospedaliero, Brescia, Italy.
authors.forename: Ugo Paolo
authors.initials: UP
authors.lastname: Guerra
authors.forename: Flavio Mariano
authors.initials: FM
authors.lastname: Nobili
authors.forename: Alessandro
authors.initials: A
authors.lastname: Padovani
authors.forename: Daniela
authors.initials: D
authors.lastname: Perani
authors.forename: Alberto
authors.initials: A
authors.lastname: Pupi
authors.forename: Sandro
authors.initials: S
authors.lastname: Sorbi
authors.forename: Marco
authors.initials: M
authors.lastname: Trabucchi
mesh_terms: D000682:Amyloid / Q000378:metabolism*; D001921:Brain / Q000000981:diagnostic imaging*; D006801:Humans; D007558:Italy; D049268:Positron-Emission Tomography / Q000592:standards*; D017410:Practice Guidelines as Topic / Q000592:standards*; D012955:Societies, Medical / Q000592:standards
chemical_list: D000682:Amyloid