title: Motor aging results from cerebellar neuron death.
abstract: As we age, movements become slower and inconsistent and require more attention. These hallmarks of aging suggest a switch from predictive to reactive motor control. Here I examine evidence supporting the hypothesis that motor aging is primarily determined by the early death of neurons in the cerebellum, a critical structure for predictive motor control.
authors.affiliation: Movement Control and Neuroplasticity Research Group, Department of Kinesiology, Biomedical Sciences Group, KU Leuven, Leuven, Belgium. Electronic address: matthieu.boisgontier@faber.kuleuven.be.
authors.forename: Matthieu P
authors.initials: MP
authors.lastname: Boisgontier
mesh_terms: D000375:Aging / Q000502:physiology*; D016923:Cell Death / Q000502:physiology*; D002531:Cerebellum / Q000254:growth & development / Q000502:physiology*; D006801:Humans; D009043:Motor Activity / Q000502:physiology*; D009474:Neurons / Q000502:physiology*
keywords: aging; cerebellum; motor control