title: A Survey of Pharmacists in Academia on the Current Practice of Estimation of Kidney Function for Antimicrobial Dosing in Adults.
abstract: OBJECTIVE
  To determine the methods used by pharmacists in academia to estimate kidney function for antimicrobial dosing.
  
  
  METHODS
  Stratified by region, a random sample of Accreditation Council for Pharmacy Education recognized Colleges of Pharmacy was selected for a total of 40 programs. Identified college Web sites were reviewed for eligible participants using the predefined inclusion/exclusion criteria. This was used to create a sampling frame from which 30% and 20% of faculty were randomly chosen and invited to participate via e-mail and mail-administered surveys, respectively.
  
  
  RESULTS
  Of the responders, 86% (31 of 36) who routinely estimate kidney function utilized the Cockcroft-Gault (CG) equation. In obese patients, 75% utilized the CG equation with or without adjustments. In patients ≥65 years, 42% adjusted serum creatinine to 1 mg/dL and 25% did not make any modifications. The majority of the responders accounted for patients with quadripalegia or bed-bound patients when estimating kidney function. In scenario examples, 51% (18 of 35) dosed an elderly female and 51% (18 of 35) a morbidly obese female as creatinine clearance ≥50 mL/min; however, 49% (17 of 35) did not.
  
  
  CONCLUSIONS
  The majority of responders utilized the CG equation for estimating kidney function with or without adjustments. Although a number of consistencies were noted, discrepancies existed, especially with elderly and obese patients.
authors.affiliation: College of Pharmacy and Health Sciences, St John's University, Queens, NY, USA Department of Pharmacy, Mount Sinai Beth Israel, New York, NY, USA jodlowst@stjohns.edu.
authors.forename: Tomasz Z
authors.initials: TZ
authors.lastname: Jodlowski
authors.affiliation: College of Pharmacy and Health Sciences, St John's University, Queens, NY, USA Department of Pharmacy, North Shore University Hospital, Sandra Atlas Bass Campus, Manhasset, NY, USA.
authors.forename: Donna
authors.initials: D
authors.lastname: Sym
authors.affiliation: College of Pharmacy and Health Sciences, St John's University, Queens, NY, USA.
authors.forename: Anthony
authors.initials: A
authors.lastname: Marziliano
authors.affiliation: College of Pharmacy and Health Sciences, St John's University, Queens, NY, USA.
authors.forename: Gina
authors.initials: G
authors.lastname: LaPan-Dennis
authors.affiliation: College of Pharmacy and Health Sciences, St John's University, Queens, NY, USA.
authors.forename: Charles R
authors.initials: CR
authors.lastname: Ashby
authors.affiliation: Division of Infectious Diseases, Mount Sinai Beth Israel, New York, NY, USA.
authors.forename: Jorg J
authors.initials: JJ
authors.lastname: Ruhe
mesh_terms: D000046:Academic Medical Centers / Q000379:methods*; D000328:Adult; D000369:Aged, 80 and over; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007677:Kidney Function Tests / Q000379:methods*; D008297:Male; D008657:Metabolic Clearance Rate / Q000187:drug effects / Q000502:physiology; D008875:Middle Aged; D010595:Pharmacists; D011897:Random Allocation; D012580:Schools, Pharmacy; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents
keywords: academia; estimation; kidney function; pharmacists; survey