title: [Intracranial atherosclerotic middle cerebral arterial stenosis research based on 3.0 Tesla high-resolution magnetic resonance imaging: recent progress].
abstract: Intracranial atherosclerotic disease (ICAD) of a major intracranial artery, including middle cerebral artery (MCA),basilar artery, is the most common causes of stroke and is associated with a high risk of recurrent stroke in China. The difficulty to treatment these high-risk disease is to identify high-risk stroke subgroups and to develop more effective treatments (aggressive medical therapy/endovascular therapy). With the benefits, including non-invasive, in vivo, and no-ionizing radiation, 3.0 Tesla high-resolution magnetic resonance imaging (HR MRI) could be used to stratify high-risk patients, monitor progression of disease, and evaluate clinical efficacy, based on MCA wall structure and plaque characteristic. HR MRI has the latency of predicting high-risk patients benefit from endovascular therapy, having a broad application prospect during psot-SAMMPRIS era. The current research on MCA stenosis using HR MRI focuses on methodoiogy, diagnosis and differential diagnosis, etiology, and lacks of clinical efficiency evaluation and prognostic analysis of ICAD treatment, especially lacks the research on in-stent restenosis, which needs further investigation.
authors.affiliation: Department of Neurosurgery, Changhai Hospital, Journal of Second Military Medical University, Shanghai 200433, Chinas. mmujiazejun@l63.com
authors.forename: Ze-Jun
authors.initials: ZJ
authors.lastname: Jia
authors.forename: Rui
authors.initials: R
authors.lastname: Zhao
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Yang
authors.forename: Qin-Hai
authors.initials: QH
authors.lastname: Huang
authors.forename: Xiao-Qun
authors.initials: XQ
authors.lastname: Deng
authors.forename: Bo
authors.initials: B
authors.lastname: Hong
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Liu
mesh_terms: D001921:Brain; D002681:China; D003251:Constriction, Pathologic; D003937:Diagnosis, Differential; D006801:Humans; D002537:Intracranial Arteriosclerosis; D008279:Magnetic Resonance Imaging; D020768:Middle Cerebral Artery / Q000473:pathology; D058226:Plaque, Atherosclerotic; D011379:Prognosis; D020521:Stroke; D016896:Treatment Outcome