title: Salpingectomy and proximal tubal occlusion for hydrosalpinx prior to in vitro fertilization: a meta-analysis of randomized controlled trials.
abstract: OBJECTIVE
  The objective of this study was to conduct a systematic review of studies comparing the pregnancy outcomes in hydrosalpinx patients treated with salpingectomy versus those treated with proximal tubal occlusion prior to in vitro fertilization (IVF).
  
  
  METHODS
  An extensive PubMed literature search was performed for the period from 1980 to December 2013 using combinations of the following keywords: "hydrosalpinx," "salpingectomy," and "tubal occlusion."
  Initially, 204 relevant studies were identified from MEDLINE and screened for retrieval. All of the randomized controlled trials comparing ovarian response and the pregnancy outcome of salpingectomy and proximal tubal occlusion for hydrosalpinx patients prior to IVF were considered eligible for analysis.
  
  
  RESULTS
  Two investigators independently reviewed the studies. The data were pooled, and the mean standard difference (SD) was calculated. Eligible randomized controlled trials were selected for this meta-analysis. There were no differences in the response days to controlled ovarian hyperstimulation (SD = -1.112, SE = 0.973, Z = -1.14, P = 0.253), number of oocytes retrieved (SD = 0.404, SE = 0.311, Z = 1.300, P = 0.194), embryos transferred per cycle (SD = -0.757, SE = 0.568, Z = -1.332, P = 0.183), and fertilized oocytes (SD = -0.006, SE = 0.130, Z = -0.045, P = 0.964) between the patients receiving salpingectomy and proximal tubal occlusion. The pooled rates for clinical pregnancy (odds ratio, 0.864; 95% confidence interval, 0.534-1.398; Z = -0.596, P = 0.551) and implantation (odds ratio, 1.558; 95% confidence interval, 0.809-3.003; Z = 1.325, P = 0.185) were not significantly different between the hydrosalpinx patients with salpingectomy versus proximal tubal occlusion.
  
  
  CONCLUSIONS
  Similar responses to controlled ovarian hyperstimulation and pregnancy outcome were observed in patients treated with salpingectomy or proximal tubal occlusion.
authors.affiliation: Associate Professor, Department of Gynecology Minimally Invasive Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Nurse-in-Charge, Department of Gynecology and Obstetrics, Hebei United University Affiliated Hospital, Heibei, China.
authors.forename: Yurong
authors.initials: Y
authors.lastname: Sun
authors.affiliation: Instructor, Department of Gynecology Minimally Invasive Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
authors.forename: Yinshu
authors.initials: Y
authors.lastname: Guo
authors.affiliation: Director and Professor, Department of Obstetrics and Gynecology, Chinese University of Hong Kong, Hong Kong.
authors.forename: Tin Chiu
authors.initials: TC
authors.lastname: Li
authors.affiliation: Director and Professor, Department of Gynecology Minimally Invasive Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Duan
mesh_terms: D000328:Adult; D005184:Fallopian Tube Diseases / Q000601:surgery*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D010062:Ovulation Induction; D011247:Pregnancy; D011256:Pregnancy Outcome; D016032:Randomized Controlled Trials as Topic; D058994:Salpingectomy; D013246:Sterilization, Tubal