title: Raman imaging of drug delivery systems.
abstract: This review article includes an introduction to the principals of Raman spectroscopy, an outline of the experimental systems used for Raman imaging and the associated important considerations and limitations of this method. Common spectral analysis methods are briefly described and examples of interesting published studies which utilised Raman imaging of pharmaceutical and biomedical devices are discussed, along with summary tables of the literature at this point in time.
authors: MacDiarmid Institute for Advanced Materials and Nanotechnology, Dodd-Walls Centre for Photonic and Quantum Technologies, Department of Chemistry, University of Otago, Dunedin, New Zealand.
authors: Geoffrey P S
authors: GP
authors: Smith
authors: Dodd-Walls Centre for Photonic and Quantum Technologies, Department of Physics, University of Auckland, New Zealand.
authors: Cushla M
authors: CM
authors: McGoverin
authors: MacDiarmid Institute for Advanced Materials and Nanotechnology, Dodd-Walls Centre for Photonic and Quantum Technologies, Department of Chemistry, University of Otago, Dunedin, New Zealand.
authors: Sara J
authors: SJ
authors: Fraser
authors: MacDiarmid Institute for Advanced Materials and Nanotechnology, Dodd-Walls Centre for Photonic and Quantum Technologies, Department of Chemistry, University of Otago, Dunedin, New Zealand. Electronic address: keith.gordon@otago.ac.nz.
authors: Keith C
authors: KC
authors: Gordon
mesh_terms: D016503:Drug Delivery Systems; D015195:Drug Design; D006801:Humans; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000737:chemistry*; D013059:Spectrum Analysis, Raman / Q000379:methods*
chemical_list: D004364:Pharmaceutical Preparations
keywords: Chemometrics; Drug delivery; Drug dissolution; Multivariate methods; Polymeric microparticles; Pre-processing; Raman imaging; Solid dispersions