title: Effect of Baduanjin exercise for hypertension: a systematic review and meta-analysis of randomized controlled trials.
abstract: This study aims to evaluate the efficacy of Baduanjin exercise for hypertension. Cochrane Library, PubMed, EMBASE, CNKI, VIP, CBM and Wanfang databases were searched. Eight randomized controlled trials (RCTs) were identified. Baduanjin significantly lowered systolic blood pressure (SBP) (WMD=-13.00 mmHg; 95% CI: -21.24 to -4.77; P=0.002), diastolic blood pressure (DBP) (WMD=-6.13 mmHg; 95% CI: -11.20 to -1.07; P=0.02), body mass index, blood glucose, triglyceride, and low-density lipoprotein-cholesterol, and improved high-density lipoprotein-cholesterol and quality of life compared to no intervention. No significant difference between Baduanjin and antihypertensive drugs on SBP (WMD=1.05 mmHg; 95% CI: -2.07 to 4.17; P=0.51) or DBP (WMD=1.90 mmHg; 95% CI: -1.22 to 5.02; P=0.23) was identified. Baduanjin plus antihypertensive drugs significantly reduced SBP (WMD=-7.49 mmHg; 95% CI: -11.39 to -3.59; P=0.0002), DBP (WMD=-3.55 mmHg; 95% CI: -5.25 to -1.85; P<0.0001), blood glucose, and total cholesterol compared to antihypertensive drugs. Baduanjin is an effective therapy for hypertension. However, further rigorously designed RCTs are still warranted.
authors: Department of Cardiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address: xiongxingjiangtcm@163.com.
authors: Xingjiang
authors: X
authors: Xiong
authors: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
authors: Pengqian
authors: P
authors: Wang
authors: Department of Biological Science and Technology, School of Life Sciences, Tsinghua University, Beijing, China.
authors: Shengjie
authors: S
authors: Li
authors: Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada.
authors: Yuqing
authors: Y
authors: Zhang
authors: Bio-organic and Natural Products Laboratory, McLean Hospital, Harvard Medical School, Belmont, MA, USA.
authors: Xiaoke
authors: X
authors: Li
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure / Q000502:physiology*; D002784:Cholesterol / Q000097:blood; D003131:Combined Modality Therapy; D015444:Exercise / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D026441:Mind-Body Therapies; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D014280:Triglycerides
chemical_list: D000959:Antihypertensive Agents; D001786:Blood Glucose; D014280:Triglycerides; D002784:Cholesterol
keywords: Baduanjin; Hypertension; Randomized controlled trial; Systematic review