title: [Combination rules of Chinese herbal prescriptions for treating unstable angina based on complex network].
abstract: OBJECTIVE
  To explore combination rules of Chinese herbal prescriptions from effective cases for treatment of unstable angina (UA).
  
  
  METHODS
  Prescription data from 156 UA patients effectively treated at Cardiovascular Diseases Centre of Xiyuan Hospital were analyzed using complex network method.
  
  
  RESULTS
  According to multi-scale analysis of backbone network and pointwise mutual information analysis, core prescriptions from the 156 UA patients were presented as follows: Rhizoma Ligustici wallichii, Radix Paeoniae rubra, Radix Codonopsis, Rhizoma Pinelliae, poria, and Angelica sinensis. Meanwhile, core couplet medicines for these patients covered Rhizoma Ligustici wallichii and Radix paeoniaerubra, Angelica sinensis and Rhizoma Ligustici wallichii, Radix Codonopsis and Rhizoma Ligustici wallichii, Rhizoma Ligustici wallichii and Rhizoma Pinelliae, Rhizoma Atractylodis Macrocephalae and poriacocos, Bulbus Alli Macrostemi and Rhizoma Pinelliae. Among different primary symptoms, there was slightly difference in core prescriptions.
  
  
  CONCLUSIONS
  The core prescriptions for the treatment of UA include blood-activating drug, phlem-resolving drugs. As an exploration of combination rules of Chinese herbal prescriptions in treating UA based on complex network, it can be used as a reference for further researches.
authors: Jing
authors: J
authors: Luo
authors: Hao
authors: H
authors: Xu
authors: Xue-Zhong
authors: XZ
authors: Zhou
authors: Ke-Ji
authors: KJ
authors: Chen
authors: Rui
authors: R
authors: Gao
mesh_terms: D029971:Angelica sinensis; D000789:Angina, Unstable / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000592:standards / Q000627:therapeutic use*; D006801:Humans; D030021:Pinellia; D018517:Plant Roots; D017410:Practice Guidelines as Topic; D055656:Prescriptions / Q000592:standards*
chemical_list: D004365:Drugs, Chinese Herbal