title: The gentle grip of a helping hand.
abstract: Using NMR spectroscopy, Zhao and colleagues, in this issue, have modeled the short-lived complex formed between the MT1-MMP hemopexin domain and a synthetic triple-helical collagen mimetic. Their model is consistent with two alternative mechanisms for the breakdown of collagen by the enzyme.
authors: Biophysics Laboratories, Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, Portsmouth PO1 2DY, UK. Electronic address: andy.pickford@port.ac.uk.
authors: Andrew R
authors: AR
authors: Pickford
mesh_terms: D003094:Collagen / Q000737:chemistry* / Q000378:metabolism*; D006801:Humans; D053511:Matrix Metalloproteinase 14 / Q000737:chemistry* / Q000378:metabolism*; D008958:Models, Molecular; D009361:Neoplasm Invasiveness / Q000503:physiopathology*
chemical_list: D003094:Collagen; D053511:Matrix Metalloproteinase 14