title: Electroacupuncture stimulation of the brachial plexus trunk on the healthy side promotes brain-derived neurotrophic factor mRNA expression in the ischemic cerebral cortex of a rat model of cerebral ischemia/reperfusion injury.
abstract: A rat model of cerebral ischemia/reperfusion was established by suture occlusion of the left middle cerebral artery. In situ hybridization results showed that the number of brain-derived neurotrophic factor mRNA-positive cells in the ischemic rat cerebral cortex increased after cerebral ischemia/ reperfusion injury. Low frequency continuous wave electroacupuncture (frequency 2-6 Hz, current intensity 2 mA) stimulation of the brachial plexus trunk on the healthy (right) side increased the number of brain-derived neurotrophic factor mRNA-positive cells in the ischemic cerebral cortex 14 days after cerebral ischemia/reperfusion injury. At the same time, electroacupuncture stimulation of the healthy brachial plexus truck significantly decreased neurological function scores and alleviated neurological function deficits. These findings suggest that electroacupuncture stimulation of the brachial plexus trunk on the healthy (right) side can greatly increase brain-derived neurotrophic factor mRNA expression and improve neurological function.
authors: Department of Special Health Care, Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, Shandong Province, China.
authors: Zongjun
authors: Z
authors: Guo
authors: Department of Emergency Treatment, Affiliated Hospital of Qingdao University Medical College, Qingdao 266003, Shandong Province, China.
authors: Lumin
authors: L
authors: Wang
keywords: brachial plexus trunk; brain-derived neurotrophic factor; cerebral cortex; electroacupuncture; in situ hybridization; ischemia/reperfusion; neural regeneration
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