title: [Vigilance level for cardiovascular risk factors in schizophrenic patients].
abstract: BACKGROUND
  Schizophrenic patients have increased cardiovascular risk factors and morbi-mortality as compared with the general population.
  
  
  OBJECTIVE
  To assess the level of French psychiatrists vigilance regarding cardiovascular risk factors in schizophrenic patients.
  
  
  METHODS
  Prospective, transverse, multicentric observational study implemented in France in 2007 and conducted by psychiatrists with a liberal activity. The included patients had to meet the following selection criteria: patients ≥ 18 years old, fulfilling the DSM-IV-TR criteria for schizophrenia, treated or not treated for their schizophrenia, with an ambulatory follow-up, without schizophreniform, schizoaffective, or other psychotic disorder. The psychiatrists "vigilance level" for a given cardiovascular risk factor was defined as a systematic investigation of this cardiovascular risk factor for at least 75% of the schizophrenic patients included in the study by the psychiatrist.
  
  
  RESULTS
  A total of 382 psychiatrists included 2242 patients, the data collected for 2222 patients were finally analysed. The mean age was 41 years old, 59% were men. The mean BMI was 27 kg/m(2), 34% of the patients were overweight, 23% were obese. The paranoid and residual schizophrenia were the most frequently described subtypes of the disease (41.3 and 25.0% respectively), 58% of the patients were moderately or markedly ill according to the CGI-S scale. Most of the patients were treated with atypical antipsychotics (77%). Only 58% of the psychiatrists were vigilant for the weight of their patients, 38% for the arterial tension, 25% for the family history of premature coronary disease, 14% for the glycemia, 12% for the triglycerides, 10% for HDL cholesterol, 6% for the waist measurement; 35% of the psychiatrists were vigilant for no cardiovascular risk factor. Less than 30% of the psychiatrists recommended their patients to other specialists to manage cardiovascular disorders.
  
  
  CONCLUSIONS
  Similarly to other countries, French psychiatrists provide insufficient care of cardiovascular risk factors of schizophrenic patients in their current clinical practice.
authors: CMME, hôpital Sainte-Anne, 75014 Paris, France; Inserm U894, université Paris Descartes, 75014 Paris France.
authors: F
authors: F
authors: Rouillon
authors: UMR 5558 CNRS, pharmaco-épidémiologie, université Claude-Bernard - Lyon-1, 69372 Lyon cedex 08, France.
authors: E
authors: E
authors: Van Ganse
authors: Département médical, Otsuka Pharmaceutical France SAS, 1, rue Eugène-et-Armand-Peugeot, 92508 Rueil-Malmaison, France. Electronic address: pvekhoff@otsuka.fr.
authors: P
authors: P
authors: Vekhoff
authors: Bristol-Myers Squibb, 92500 Rueil-Malmaison, France.
authors: R
authors: R
authors: Arnaud
authors: Bristol-Myers Squibb, 92500 Rueil-Malmaison, France.
authors: L
authors: L
authors: Depret-Bixio
authors: Bristol-Myers Squibb, 92500 Rueil-Malmaison, France.
authors: A
authors: A
authors: Dillenschneider
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000453:epidemiology*; D003299:Cooperative Behavior; D003430:Cross-Sectional Studies; D005260:Female; D005602:France; D006306:Health Surveys; D006801:Humans; D033183:Interdisciplinary Communication; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000139:chemically induced / Q000175:diagnosis / Q000453:epidemiology; D050177:Overweight / Q000139:chemically induced / Q000175:diagnosis / Q000453:epidemiology; D011446:Prospective Studies; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*
chemical_list: D014150:Antipsychotic Agents
keywords: Cardiovascular risk factors; Metabolic syndrome; Risque cardiovasculaire; Schizophrenia; Schizophrénie; Syndrome métabolique; Vigilance