title: Proceedings: moving toward cell-based therapies for liver disease.
abstract: Despite available medical therapy and organ transplantation, a significant unmet medical need remains for the treatment of liver failure, end-stage liver disease, and liver-based inborn errors of metabolism. Liver cell transplantation has the potential to address this need; however, the field is in search of a suitable cell therapeutic. The ability to reproducibly generate a well-characterized source of engraftable and functional liver cells has continued to be a challenge. Recent progress with tissue-derived stem/progenitor cells and pluripotent stem cell-derived cells now offers the field the opportunity to address this challenge.
authors: California Institute for Regenerative Medicine, San Francisco, California, USA lkadyk@cirm.ca.gov.
authors: Lisa C
authors: LC
authors: Kadyk
authors: California Institute for Regenerative Medicine, San Francisco, California, USA.
authors: Lila R
authors: LR
authors: Collins
authors: California Institute for Regenerative Medicine, San Francisco, California, USA.
authors: Neil J
authors: NJ
authors: Littman
authors: California Institute for Regenerative Medicine, San Francisco, California, USA.
authors: Maria T
authors: MT
authors: Millan
mesh_terms: D064987:Cell- and Tissue-Based Therapy / Q000379:methods / Q000639:trends; D006801:Humans; D008107:Liver Diseases / Q000628:therapy*; D039904:Pluripotent Stem Cells / Q000637:transplantation*; D033581:Stem Cell Transplantation
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