title: The critical role of peptide chemistry in the life sciences.
abstract: Peptide chemistry plays a key role in the synthesis and study of protein molecules and their functions. Modern ligation methods enable the total synthesis of enzymes and the systematic dissection of the chemical basis of enzyme catalysis. Predicted developments in peptide science are described.
authors: Department of Chemistry, Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, USA.
authors: Stephen B H
authors: SB
authors: Kent
mesh_terms: D001690:Biological Science Disciplines / Q000379:methods / Q000639:trends*; D002384:Catalysis; D056246:Chemistry, Analytic / Q000639:trends*; D004798:Enzymes / Q000737:chemistry / Q000494:pharmacology; D005544:Forecasting; D006801:Humans; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D057786:Peptidomimetics / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D011499:Protein Processing, Post-Translational; D022223:Vaccines, Subunit / Q000138:chemical synthesis / Q000494:pharmacology; D014614:Vaccines, Synthetic
chemical_list: D004798:Enzymes; D010455:Peptides; D057786:Peptidomimetics; D022223:Vaccines, Subunit; D014614:Vaccines, Synthetic
keywords: Analytical characterization of synthetic peptides; Chemical protein synthesis; Enzymes; Novel protein covalent topologies; Post-translational modifications; Synthetic peptide vaccines