title: Acne patients frequently associated with abnormal plasma lipid profile.
abstract: This study was designed to investigate the relationship between plasma lipid profile and acne. Acne patients (n = 181) and healthy volunteers (n = 130) matched in terms of both age and sex were enrolled. Plasma total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol, low-density lipoprotein cholesterol (LDL-C) and lipoprotein (LP)(a) levels were measured. TC, LDL-C and LP(a) levels in male and female patients with severe acne were significantly higher than in the healthy control group (P < 0.05). TG in male patients with severe and moderate acne was significantly higher than in the healthy control group (P < 0.05). LP(a) in male and female patients with mild, moderate and severe acne was significantly higher than in the healthy control group (P < 0.05). The constituent ratio of male and female patients with TC, TG, LDL-C and LP(a) over the normal range was significantly higher than in the healthy control group. In this study, acne patients were frequently associated with abnormal lipid profile, providing a new basis for further exploration of the pathogenesis, as well as new treatments, of acne vulgaris.
authors: Dermatological Department, Clinical Laboratory, Medical Center and Research Department of The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.
authors: Hao
authors: H
authors: Jiang
authors: Chang Yi
authors: CY
authors: Li
authors: Lu
authors: L
authors: Zhou
authors: Bin
authors: B
authors: Lu
authors: Yinghui
authors: Y
authors: Lin
authors: Xiaoqi
authors: X
authors: Huang
authors: Bin
authors: B
authors: Wei
authors: Qiang
authors: Q
authors: Wang
authors: Leping
authors: L
authors: Wang
authors: Jianqi
authors: J
authors: Lu
mesh_terms: D000152:Acne Vulgaris / Q000097:blood*; D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D017270:Lipoprotein(a) / Q000097:blood; D008297:Male; D012720:Severity of Illness Index; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood; D055815:Young Adult
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D017270:Lipoprotein(a); D014280:Triglycerides
keywords: acne vulgaris; hyperlipidemia; hypolipidemia; lipid profile; lipoprotein(a)