title: Pancreas Metastasization of Nasal NK/T-Cell Lymphoma: A Case Report.
abstract: We report here a case of nasal natural killer/T-cell lymphoma with metastasization into the pancreas. A 43-year-old Chinese female patient presented with right nasal obstruction and purulent rhinorrhea that lasted for the past half year and worsened gradually despite antibiotic medical treatment. Physical examination revealed a mass in the right nasal cavity and an enlarged lymph node in the right submandibular region. A PET/CT scan and immunostaining of the resectate led to a diagnosis of nasal natural killer/T-cell lymphoma, clinical stage IIE, and the International Prognostic Index score of 1. The patient received radiotherapy followed by four cycles of the CHOP chemotherapy. A complete remission was achieved, and the patient was disease-free for 9 months. On a subsequent follow-up, abdominal ultrasound scan, enhanced abdominal CT scan, and ultrasound-guided fine-needle aspiration biopsy revealed pancreatic metastasis secondary to nasal lymphoma. Radiotherapy (40 Gy) to the whole pancreas was done, followed by two courses of the SMILE regime chemotherapy, leading to a complete remission. At the moment, the patient is undergoing subsequent chemotherapy.
authors: Department of Radiation Oncology, The Central Hospital of Xuzhou, Liberation, No. 199 South Rd, Xuzhou, 221009, Jiang Su, China.
authors: Chong
authors: C
authors: Zhou
authors: Department of Radiation Oncology, The Central Hospital of Xuzhou, Liberation, No. 199 South Rd, Xuzhou, 221009, Jiang Su, China.
authors: Xiangzhao
authors: X
authors: Bu
authors: Department of Radiation Oncology, The Central Hospital of Xuzhou, Liberation, No. 199 South Rd, Xuzhou, 221009, Jiang Su, China.
authors: Xiangyang
authors: X
authors: Li
authors: Department of Radiation Oncology, The Central Hospital of Xuzhou, Liberation, No. 199 South Rd, Xuzhou, 221009, Jiang Su, China.
authors: Ling
authors: L
authors: Liu
authors: Department of Radiation Oncology, The Central Hospital of Xuzhou, Liberation, No. 199 South Rd, Xuzhou, 221009, Jiang Su, China.
authors: Xiaomei
authors: X
authors: Xie
authors: Department of Pathology, The Central Hospital of Xuzhou, Xuzhou, 221009, China.
authors: Shichao
authors: S
authors: Zhuo
authors: Department of Radiation Oncology, The Central Hospital of Xuzhou, Liberation, No. 199 South Rd, Xuzhou, 221009, Jiang Su, China. contribution069@163.com.
authors: Haitao
authors: H
authors: Yin
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy; D016399:Lymphoma, T-Cell / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D009669:Nose Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary / Q000628:therapy; D000072078:Positron Emission Tomography Computed Tomography; D014463:Ultrasonography
keywords: Case report; Lymphoma; Metastasization; Pancreas