title: [Efficacy analysis of endoscopic submucosal dissection for the early cancer and precancerous lesions in the remnant stomach].
abstract: OBJECTIVE
  To determine the feasibility and efficacy of endoscopic submucosal dissection(ESD) in treating early gastric cancer(EGC) and precancerous lesions in the remnant stomach of patients after gastrectomy.
  
  
  METHODS
  Clinical data of 36 patients with EGC and precancerous lesions in remnant stomach undergoing ESD in Endoscopy Center of Zhongshan Hospital from January 2008 to December 2013 were retrospectively analyzed. Operative, postoperative conditions and long-term follow-up of these patients were evaluated.
  
  
  RESULTS
  Both the success rate and the complete resection rate were 100%. The average maximum diameter of the tumor was 1.5(range 0.6-4.5) cm. During the ESD process, two bleeding cases were treated successfully by endoscopic hemostasis. The average operation time was 40(10-80) min. The delayed hemorrhage developed in 2 cases within 1-3 days after operation, and were also treated successfully by endoscopic hemostasis. There was no perforation or delayed perforation. No emergency surgery was required for the complication. Twelve cases were diagnosed as mild-moderate dysplasia, 7 cases as high grade intraepithelial neoplasia, 16 cases as hyperplastic polyps, and 1 case as signet ring cell carcinoma with T1 stage, who underwent operation for resecting gastric stump and lymph node dissection 7 days after ESD without subsequent follow-up. The curative resection rate was 92.7%(35/36). The median follow-up of the remaining 35 patients was 36(6-78) months without discomfort and recurrence under gastroscopy.
  
  
  CONCLUSIONS
  ESD is safe and effective for EGC and precancerous lesions in the remnant stomach.
authors: Endoscopy Center, Zhongshan Hospital, Fudan University, Shanghai 200032, China. zhongyunshifd@126.com.
authors: Qiang
authors: Q
authors: Shi
authors: Junyu
authors: J
authors: Zhu
authors: Chunhong
authors: C
authors: Dai
authors: Pinghong
authors: P
authors: Zhou
authors: Meidong
authors: M
authors: Xu
authors: Weifeng
authors: W
authors: Chen
authors: Zhong
authors: Z
authors: Ren
authors: Tao
authors: T
authors: Chen
authors: Shilun
authors: S
authors: Cai
authors: Yiren
authors: Y
authors: Wu
authors: Yunshi
authors: Y
authors: Zhong
authors: Liqing
authors: L
authors: Yao
mesh_terms: D000230:Adenocarcinoma; D004210:Dissection; D005743:Gastrectomy; D005753:Gastric Mucosa; D018530:Gastric Stump; D005773:Gastroscopy; D016558:Hemostasis, Endoscopic; D006801:Humans; D008197:Lymph Node Excision; D009364:Neoplasm Recurrence, Local; D061646:Operative Time; D012189:Retrospective Studies; D013274:Stomach Neoplasms