title: Preoperative functional MRI localization of language areas in Chinese patients with brain tumors: Validation with intraoperative electrocortical mapping.
abstract: Ten Chinese patients with brain tumors involving language regions were selected. Preoperative functional MRI was performed to locate Broca's or Wernicke's area, and the cortex that was essential for language function was determined by electrocortical mapping. A site-by-site comparison between functional MRI and electrocortical mapping was performed with the aid of a neuronavigation device. Results showed that the sensitivity and specificity of preoperative functional MRI were 80.0% and 85.0% in Broca's area and 66.6% and 85.2% in Wernicke's area, respectively. These experimental findings indicate that functional MRI is an accurate, reliable technique with which to identify the location of Wernicke's area or Broca's area in patients with brain tumors.
authors: Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China.
authors: Hechun
authors: H
authors: Xia
authors: Department of Neurosurgery, Hanzhong Central Hospital, Hanzhong 723000, Shaanxi Province, China.
authors: Wei
authors: W
authors: Huang
authors: Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China.
authors: Liang
authors: L
authors: Wu
authors: Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China.
authors: Hui
authors: H
authors: Ma
authors: Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China.
authors: Xiaodong
authors: X
authors: Wang
authors: Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China.
authors: Xuexin
authors: X
authors: Chen
authors: Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China.
authors: Shengyu
authors: S
authors: Sun
authors: Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan 750004, Ningxia Hui Autonomous Region, China.
authors: Xiaoxiong
authors: X
authors: Jia
keywords: Broca's area; Chinese language; Wernicke's area; brain mapping; brain tumor; functional MRI; intraoperative electrocortical mapping; neural regeneration; regeneration
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