title: Imaging of adverse reactions to metal debris.
abstract: Hip replacements with metal-on-metal components can cause a spectrum of adverse tissue reactions-from benign localized fibrosis and chronic inflammation to delayed hypersensitivity response. In addition to history, physical examination, and relevant laboratory data, imaging plays a critical role in the evaluation of hip arthroplasties. Imaging assessment begins with radiographs and may be followed by ultrasound, computed tomography, or MRI. MRI optimized for metal artifact reduction is the most sensitive and specific imaging modality and is essential in assessing the spectrum of metal-related adverse tissue reactions. In this article, we discuss the history, pathophysiology, and imaging findings of adverse reactions to metal debris.
authors: Department of Radiology, University of Washington, Seattle, Washington.
authors: Ezekiel
authors: E
authors: Maloney
authors: Department of Radiology, University of Washington, Seattle, Washington.
authors: Alice S
authors: AS
authors: Ha
authors: Department of Radiology and Imaging, Hospital for Special Surgery, New York, New York.
authors: Theodore T
authors: TT
authors: Miller
mesh_terms: D019644:Arthroplasty, Replacement, Hip; D003952:Diagnostic Imaging; D019544:Equipment Failure Analysis / Q000379:methods*; D005355:Fibrosis / Q000175:diagnosis / Q000209:etiology; D005471:Fluoroscopy; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000473:pathology; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000175:diagnosis / Q000209:etiology; D007249:Inflammation / Q000175:diagnosis / Q000209:etiology; D008279:Magnetic Resonance Imaging; D061825:Metal-on-Metal Joint Prostheses / Q000009:adverse effects*; D008670:Metals; D011183:Postoperative Complications / Q000175:diagnosis*; D011475:Prosthesis Failure; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D008670:Metals