title: PharmGKB summary: very important pharmacogene information for human leukocyte antigen B.
authors: Departments of aGenetics bBioengineering, Stanford University, Stanford cDepartment of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA.
authors: Julia M
authors: JM
authors: Barbarino
authors: Deanna L
authors: DL
authors: Kroetz
authors: Teri E
authors: TE
authors: Klein
authors: Russ B
authors: RB
authors: Altman
mesh_terms: D005787:Gene Frequency; D056726:Genetic Association Studies; D014644:Genetic Variation; D015235:HLA-B Antigens / Q000235:genetics*; D006801:Humans; D010597:Pharmacogenetics
chemical_list: D015235:HLA-B Antigens
references: J Infect Dis. 2008 Sep 15;198(6):864-7
references: 18684101
references: Nucleic Acids Res. 2011 Jan;39(Database issue):D1171-6
references: 21071412
references: Antivir Ther. 2007;12(7):1027-32
references: 18018760
references: Pharmacogenet Genomics. 2014 Feb;24(2):94-112
references: 24336023
references: Pharmacogenet Genomics. 2011 May;21(5):303-7
references: 21301380
references: J Allergy Clin Immunol Pract. 2014 Jan-Feb;2(1):21-33
references: 24565765
references: Lancet. 2002 Mar 30;359(9312):1121-2
references: 11943262
references: Pharmacogenomics. 2012 Jul;13(10):1193-201
references: 22909208
references: Ther Drug Monit. 2010 Dec;32(6):762-6
references: 21068649
references: J Clin Pharmacol. 2013 Jul;53(7):675-9
references: 23381951
references: Pharmacogenomics. 2010 Mar;11(3):349-56
references: 20235791
references: AIDS. 2013 Jan 28;27(3):484-5
references: 23032409
references: Br J Dermatol. 2012 Jul;167(1):44-9
references: 22348415
references: Basic Clin Pharmacol Toxicol. 2011 Jul;109(1):42-6
references: 21306565
references: Drug Saf. 2008;31(8):695-702
references: 18636788
references: Invest Ophthalmol Vis Sci. 2000 Nov;41(12):3702-8
references: 11053265
references: Nature. 2010 May 20;465(7296):350-4
references: 20445539
references: Int J Immunogenet. 2010 Dec;37(6):467-75
references: 20637045
references: Clin Pharmacol Ther. 2012 Dec;92(6):757-65
references: 23132554
references: Epilepsia. 2010 Dec;51(12):2461-5
references: 21204807
references: Pharmacogenetics. 2004 Jun;14(6):335-42
references: 15247625
references: Clin Infect Dis. 2008 Apr 1;46(7):1111-8
references: 18444831
references: Genome Res. 2003 Dec;13(12):2621-36
references: 14656967
references: Nat Med. 2008 Dec;14(12):1343-50
references: 19029983
references: Pharmacogenomics. 2012 Feb;13(3):247-9
references: 22304574
references: AIDS. 1999 Jul 30;13(11):1419-20
references: 10449301
references: Pharmacogenomics J. 2013 Feb;13(1):60-9
references: 21912425
references: AIDS. 2007 Jun 19;21(10):1233-44
references: 17545699
references: Nucleic Acids Res. 2011 Jan;39(Database issue):D913-9
references: 21062830
references: Clin Infect Dis. 2006 Jul 1;43(1):99-102
references: 16758424
references: Pharmacogenomics. 2014 Apr;15(6):857-68
references: 24897291
references: Arthritis Care Res (Hoboken). 2012 Oct;64(10):1431-46
references: 23024028
references: Pediatr Allergy Immunol. 2013 May;24(3):299-303
references: 23551241
references: J Antimicrob Chemother. 2010 Aug;65(8):1567-9
references: 20534626
references: Int J Immunogenet. 2013 Aug;40(4):311-5
references: 23280011
references: Hum Mol Genet. 2012 Oct 1;21(19):4334-47
references: 22718199
references: J Allergy Clin Immunol. 2011 Mar;127(3 Suppl):S60-6
references: 21354501
references: Intern Med J. 2012 Apr;42(4):411-6
references: 21790926
references: Pediatr Infect Dis J. 2009 Jun;28(6):552
references: 19483528
references: Pharmacogenomics. 2011 Jun;12(6):809-14
references: 21510768
references: J Dermatol. 2012 Dec;39(12):1077-8
references: 22901319
references: Clin Pharmacol Ther. 2013 Jul;94(1):142-9
references: 23588310
references: Nat Rev Genet. 2004 Dec;5(12):889-99
references: 15573121
references: BMC Neurol. 2013;13:75
references: 23829937
references: Epilepsia. 2014 Apr;55(4):496-506
references: 24597466
references: Seizure. 2012 Oct;21(8):614-8
references: 22818943
references: Int J Dermatol. 2011 Feb;50(2):221-4
references: 21244392
references: Nature. 2004 Apr 1;428(6982):486
references: 15057820
references: Genet Test Mol Biomarkers. 2012 Sep;16(9):1111-4
references: 22913531
references: Pharmacogenet Genomics. 2006 May;16(5):353-7
references: 16609367
references: Clin Pharmacol Ther. 1997 Sep;62(3):287-92
references: 9333104
references: Trop Med Int Health. 2011 Feb;16(2):200-4
references: 21091860
references: Pain Pract. 2012 Mar;12(3):202-8
references: 21676164
references: Clin Pharmacol Ther. 2013 Feb;93(2):153-8
references: 23232549
references: Nature. 2012 Jun 28;486(7404):554-8
references: 22722860
references: Pharmacol Rev. 2006 Mar;58(1):87-114
references: 16507884
references: Epilepsy Res. 2011 Nov;97(1-2):190-7
references: 21917426
references: Eur J Clin Pharmacol. 2011 Sep;67(9):885-7
references: 21424386
references: J Allergy Clin Immunol. 2000 Jan;105(1 Pt 1):157-65
references: 10629466
references: AIDS. 2012 Jul 17;26(11):F21-9
references: 22617051
references: Clin Pharmacokinet. 2008;47(6):351-71
references: 18479171
references: Clin Biochem Rev. 2013 Feb;34(1):15-38
references: 23592889
references: JAMA Dermatol. 2013 Sep;149(9):1025-32
references: 23884208
references: Epilepsy Behav. 2010 Nov;19(3):405-8
references: 20833111
references: Pharmacogenomics. 2010 Jul;11(7):973-87
references: 20602616
references: J Virol. 2013 Apr;87(7):4043-51
references: 23365442
references: Arch Dis Child. 2014 Jun;99(6):581-4
references: 24225276
references: Am J Pathol. 2014 Jun;184(6):1677-82
references: 24731753
references: Nat Genet. 2013 Jul;45(7):730-8
references: 23749187
references: Clin Pharmacol Ther. 2012 Apr;91(4):734-8
references: 22378157
references: Nat Genet. 2011 Aug;43(8):761-7
references: 21743469
references: Nat Genet. 2009 Jul;41(7):816-9
references: 19483685
references: Seizure. 2013 Mar;22(2):103-8
references: 23159358
references: Eur J Clin Pharmacol. 2004 May;60(3):155-9
references: 15024534
references: J Dermatol Sci. 2014 Feb;73(2):101-9
references: 24268988
references: CMAJ. 2010 Mar 23;182(5):476-80
references: 19933789
references: Seizure. 2011 Mar;20(2):160-2
references: 21169036
references: J Rheumatol. 2013 Jan;40(1):96-7
references: 23280169
references: Pharmacogenomics J. 2014 Aug;14(4):316-21
references: 24394201
references: N Engl J Med. 2011 Mar 24;364(12):1126-33
references: 21428768
references: Expert Opin Drug Saf. 2010 Jan;9(1):15-21
references: 20001755
references: Rheumatology (Oxford). 2012 Sep;51(9):1529-39
references: 22513152
references: J Gen Virol. 2011 Feb;92(Pt 2):247-68
references: 21106806
references: Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):9959-64
references: 22645359
references: Epilepsy Res. 2010 Dec;92(2-3):226-30
references: 21071176
references: N Engl J Med. 2008 Feb 7;358(6):568-79
references: 18256392
references: Br J Dermatol. 2013 Sep;169(3):660-5
references: 23600531
references: Proc Natl Acad Sci U S A. 2005 Mar 15;102(11):4134-9
references: 15743917
references: Asian Pac J Allergy Immunol. 2011 Sep;29(3):290-3
references: 22053601
references: JAMA. 2014 Aug 6;312(5):525-34
references: 25096692
references: Pharmacogenomics J. 2006 Jul-Aug;6(4):265-8
references: 16415921
references: Best Pract Res Clin Rheumatol. 2006 Jun;20(3):601-9
references: 16777585
references: J Acquir Immune Defic Syndr. 2007 May 1;45(1):1-3
references: 17356469
references: Clin Pharmacol Ther. 2011 May;89(5):662-73
references: 21412232
references: Nat Rev Immunol. 2011 Dec;11(12):823-36
references: 22076556
references: Pharmacogenomics J. 2014 Jun;14(3):281-8
references: 24322785
references: N Engl J Med. 2011 Mar 24;364(12):1134-43
references: 21428769
references: Epilepsia. 2010 May;51(5):926-30
references: 20345939
references: Nat Genet. 2006 Oct;38(10):1166-72
references: 16998491
references: Indian J Dermatol Venereol Leprol. 2009 Nov-Dec;75(6):579-82
references: 19915237
references: Pharmacogenomics. 2008 Nov;9(11):1617-22
references: 19018717
references: Dermatology. 2007;215(1):86-8
references: 17587850
references: Seizure. 2011 Jul;20(6):446-8
references: 21397523
references: Nephrol Dial Transplant. 2011 Nov;26(11):3567-72
references: 21393610
references: AIDS. 2002 Nov 8;16(16):2223-5
references: 12409746
references: Lancet. 2002 Mar 2;359(9308):727-32
references: 11888582
references: AIDS. 2007 Nov 30;21(18):2533-4
references: 18025891
references: BMC Genomics. 2013;14:355
references: 23714642
references: Clin Pharmacol Ther. 2013 Sep;94(3):324-8
references: 23695185
references: Nature. 1992 Dec 3;360(6403):434-9
references: 1280333
references: Nature. 1991 Aug 15;352(6336):595-600
references: 1865923
references: Tissue Antigens. 2012 Jul;80(1):1-11
references: 22651253
references: Nat Genet. 2010 Aug;42(8):698-702
references: 20622878
references: Pharmacogenet Genomics. 2014 May;24(5):276-82
references: 24625462
references: Pharmacogenomics. 2006 Sep;7(6):813-8
references: 16981842
references: AIDS. 2003 Dec 5;17(18):2581-91
references: 14685052
references: J Clin Pharmacol. 2009 Dec;49(12):1483-7
references: 19617466
references: Pharmacogenomics. 2004 Mar;5(2):203-11
references: 15016610
references: Lancet. 2007 Apr 21;369(9570):1379-90
references: 17448825
references: Pharmacotherapy. 2007 Oct;27(10):1425-39
references: 17896897
references: Pharmacol Rep. 2013;65(5):1256-62
references: 24399721
references: Int J Immunogenet. 2013 Feb;40(1):72-6
references: 23302098
references: Arthritis Rheumatol. 2014 Feb;66(2):284-94
references: 24504800
references: Allergol Int. 2006 Mar;55(1):17-25
references: 17075282
references: Epilepsy Behav. 2011 Feb;20(2):390-1
references: 21216202
references: Pharmacogenet Genomics. 2008 Feb;18(2):99-107
references: 18192896
references: Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2709-14
references: 10694578
references: Pharmacogenet Genomics. 2009 Sep;19(9):704-9
references: 19696695
references: Tissue Antigens. 2011 Jul;78(1):11-20
references: 21501118
references: Epilepsia. 2008 Dec;49(12):2087-91
references: 18637831
references: Arthritis Rheumatol. 2014 Feb;66(2):231-41
references: 24504793
references: JAMA. 2008 Dec 24;300(24):2845
references: 19109108
references: Expert Opin Pharmacother. 2010 Sep;11(13):2153-62
references: 20536296
references: Nat Rev Immunol. 2008 Aug;8(8):607-18
references: 18641646
references: Pharmacogenet Genomics. 2006 Apr;16(4):297-306
references: 16538176
references: Pharmacogenomics. 2008 Oct;9(10):1543-6
references: 18855540
references: Int J Med Sci. 2013;10(2):164-70
references: 23329888
references: Eur J Clin Pharmacol. 2010 Jul;66(7):689-96
references: 20390258
references: J Huazhong Univ Sci Technolog Med Sci. 2014 Feb;34(1):146-50
references: 24496695
references: Life Sci. 2004 Jan 2;74(7):827-34
references: 14659971
references: Epilepsia. 2013 Jul;54(7):1307-14
references: 23692434
references: J Virol. 2012 Jan;86(2):919-29
references: 22090105
references: AIDS. 2013 Jan 28;27(3):491-2
references: 23291545
references: Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4180-5
references: 15024131
references: Basic Clin Pharmacol Toxicol. 2012 Jul;111(1):58-64
references: 22348435
references: J Immunol. 2013 May 15;190(10):4956-64
references: 23596311
references: Hum Immunol. 2012 Feb;73(2):164-7
references: 22197535
references: Hum Mol Genet. 2011 Mar 1;20(5):1034-41
references: 21149285
references: J Infect Dis. 2010 Apr 15;201(8):1141-9
references: 20205591
references: N Engl J Med. 1994 Nov 10;331(19):1272-85
references: 7794310
references: J Immunol. 2014 Apr 1;192(7):2984-93
references: 24591375
references: J Allergy Clin Immunol. 2012 Jun;129(6):1562-9.e5
references: 22322005