title: Shorter spontaneous fixation durations in infants with later emerging autism.
abstract: Little is known about how spontaneous attentional deployment differs on a millisecond-level scale in the early development of autism spectrum disorders (ASD). We measured fine-grained eye movement patterns in 6-to 9-month-old infants at high or low familial risk (HR/LR) of ASD while they viewed static images. We observed shorter fixation durations (i.e. the time interval between saccades) in HR than LR infants. Preliminary analyses indicate that these results were replicated in a second cohort of infants. Fixation durations were shortest in those infants who went on to receive an ASD diagnosis at 36 months. While these findings demonstrate early-developing atypicality in fine-grained measures of attentional deployment early in the etiology of ASD, the specificity of these effects to ASD remains to be determined.
authors: Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK.
authors: Sam V
authors: SV
authors: Wass
authors: Centre for Brain and Cognitive Development, Birkbeck, University of London, UK.
authors: Emily J H
authors: EJ
authors: Jones
authors: Centre for Brain and Cognitive Development, Birkbeck, University of London, UK.
authors: Teodora
authors: T
authors: Gliga
authors: Centre for Brain and Cognitive Development, Birkbeck, University of London, UK.
authors: Tim J
authors: TJ
authors: Smith
authors: King's College London, Institute of Psychiatry, Psychology &Neuroscience, Department of Psychology, UK.
authors: Tony
authors: T
authors: Charman
authors: Centre for Brain and Cognitive Development, Birkbeck, University of London, UK.
authors: Mark H
authors: MH
authors: Johnson
mesh_terms: D000067877:Autism Spectrum Disorder / Q000175:diagnosis*; D005133:Eye Movements; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D013997:Time Factors
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