title: Effects of food enriched with egg yolk hydrolysate (bone peptide) on bone metabolism in orchidectomized dogs.
abstract: We examined the effects of chicken egg hydrolysate (also known as "bone peptide" or BP) on bone metabolism in 5- to 8-month-old orchidectomized dogs. The bone formation marker serum bone alkaline phosphatase (BAP) and the bone resorption marker urine deoxypyridinoline (DPD) were used as indicators to measure changes in bone metabolism. The following results were observed that Serum BAP was higher in dogs fed BP-enriched food throughout the clinical investigation. Serum BAP was statistically significantly higher in dogs fed BP-enriched food than in dogs fed non-BP-enriched food at 2 months after orchidectomy. This suggests that BP promoted bone formation immediately after orchidectomy.
authors: Laboratory of Veterinary Physiology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.
authors: Toyokazu
authors: T
authors: Kobayashi
authors: Hiroshi
authors: H
authors: Koie
authors: Arisa
authors: A
authors: Watanabe
authors: Arisa
authors: A
authors: Ino
authors: Kazuya
authors: K
authors: Watabe
authors: Mujo
authors: M
authors: Kim
authors: Kiichi
authors: K
authors: Kanayama
authors: Kazuya
authors: K
authors: Otsuji
mesh_terms: D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D004032:Diet / Q000662:veterinary; D019587:Dietary Supplements; D004285:Dogs; D004530:Egg Yolk / Q000737:chemistry*; D008297:Male; D009919:Orchiectomy / Q000662:veterinary*; D011492:Protein Hydrolysates / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D011492:Protein Hydrolysates
references: Bone. 1994 Jan-Feb;15(1):15-20
references: 8024845
references: Vet Clin Pathol. 1993;22(1):17-23
references: 12669283
references: J Am Vet Med Assoc. 1991 Apr 1;198(7):1193-203
references: 2045340
references: J Nutr. 2002 Jun;132(6 Suppl 2):1742S-4S
references: 12042513
references: Biosci Biotechnol Biochem. 2004 Nov;68(11):2388-90
references: 15564680
references: Menopause. 2011 Mar;18(3):307-13
references: 21107301
references: Science. 1999 Dec 3;286(5446):1946-9
references: 10583956
references: J Vet Med Sci. 2000 Jan;62(1):69-73
references: 10676893
references: J Bone Miner Res. 1994 Mar;9(3):395-400
references: 8191934
references: J Bone Miner Res. 1997 Nov;12(11):1833-43
references: 9383688
references: J Am Vet Med Assoc. 2004 Feb 1;224(3):380-7
references: 14765797
references: Nihon Yakurigaku Zasshi. 1984 Jul;84(1):91-8
references: 6489866
references: Bone Miner. 1990 Jan;8(1):87-96
references: 2106358
references: J Clin Endocrinol Metab. 2007 Apr;92(4):1415-23
references: 17264183