title: Serum levels of 25-hydroxyvitamin D and functional outcome among postmenopausal women with hip fracture.
abstract: OBJECTIVE
  The main objective of the current study was to assess the distribution and its prognostic value of serum 25-hydroxyvitamin D (25[OH] D) levels assessed at admission in Chinese postmenopausal women with hip fracture.
  
  
  METHODS
  From January 1, 2012 to December 31, 2013, all postmenopausal women with first-ever hip fracture were recruited to participate in the study. Serum 25[OH] D levels were measured at admission. The functional evaluation at the time of discharge was performed by the Barthel Index (BI). The prognostic value of 25[OH] D to predict the functional outcome within discharge was analyzed by logistic regression analysis, after adjusting for the possible confounders.
  
  
  RESULTS
  In our study, 261 patients were included and assessed. In the 76 patients with an unfavorable functional outcome, serum 25(OH) D levels were lower compared with those in patients with a favorable outcome [11.8(IQR, 9.9-16.1) ng/ml; 16.8(IQR, 13.6-21.4) ng/ml, respectively; P<0.0001]. In multivariate analysis, there was an increased risk of unfavorable outcome associated with serum 25(OH) D levels ≤ 20 ng/ml (OR 5.24, 95%CI: 3.11-8.15; P<0.0001) after adjusting for possible confounders.
  
  
  CONCLUSIONS
  Our data support an association between serum 25[OH] D levels and prognosis in Chinese postmenopausal women with hip fracture.
authors: Department of Orthopedics, Linyi People's Hospital, Linyi, Shandong province, People's Republic of China.
authors: Lan-Mei
authors: LM
authors: Liu
authors: Department of Orthopedics, Linyi People's Hospital, Linyi, Shandong province, People's Republic of China.
authors: Shuai-Hua
authors: SH
authors: Wang
authors: Department of Orthopedics, Linyi People's Hospital, Linyi, Shandong province, People's Republic of China.
authors: Chuan-Sheng
authors: CS
authors: Fu
authors: Department of Orthopedics, Linyi People's Hospital, Linyi, Shandong province, People's Republic of China.
authors: Xiang-Zhen
authors: XZ
authors: Han
authors: Hand and Foot Surgery Department, Shandong Provincial Hospital, Jinan, Shandong province, People's Republic of China.
authors: Bao-Fu
authors: BF
authors: Wei
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006620:Hip Fractures / Q000097:blood* / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000097:blood; D017698:Postmenopause; D011379:Prognosis; D020127:Recovery of Function; D016896:Treatment Outcome; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D
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