title: Novel therapeutic approach for the treatment of periodontitis by curcumin.
abstract: OBJECTIVE
  The aim of the present study was to evaluate the clinical and microbiological efficacy of locally delivered 1% curcumin gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis.
  
  
  METHODS
  The study group consisted of 25 patients, belonging to both sex, aged between 21-45 years. All patients diagnosed as chronic periodontitis with periodontal pockets of depth >5mm bilaterally were randomly selected. A split mouth design was followed and the patients received a complete prophylaxis including scaling and root planing. Examination of plaque index, bleeding index, probing pocket depth and clinical attachment level were measured for each patient. The test group received 1% curcumin gel along with scaling and root planing whereas the control group received scaling and root planing alone followed by microbiological samples taken at baseline, 1, 3 and 6 months interval.
  
  
  RESULTS
  The 1% curcumin gel appeared to provide significant improvements in clinical parameters. Microbiological counts of Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum and capnocytophaga showed significant reduction in periopathogens at the test sites after six months when compared with that of control sites.
  
  
  CONCLUSIONS
  Locally delivered 1% curcumin gel was more effective in inhibiting the growth of oral bacteria when used as an adjunct to SRP in the treatment of chronic periodontitis.
authors: Private Practioner, Department of Periodontics, New you Cosmetic Clinic , Bangalore, Karnataka, India .
authors: Madhu
authors: M
authors: Bhatia
authors: Lecturer, Department of Periodontics, Narsinhbhai Patel Dental College , North Gujarat, India.
authors: Shilpa Sarvesh
authors: SS
authors: Urolagin
authors: Private Practioner, Department of Oral & Maxillofacial Surgery, New you Cosmetic Clinic , Bangalore, Karnataka, India .
authors: Kishore Babu
authors: KB
authors: Pentyala
authors: Reader, Department of Oral & Maxillofacial Surgery, Narsinhbhai Patel Dental College , North Gujarat, India .
authors: Sarvesh Basavaraj
authors: SB
authors: Urolagin
authors: Reader, Department of Periodontics, KLE V. K. Institute of Dental Sciences , Belgaum, Karnataka, India .
authors: Menaka
authors: M
authors: K B
authors: Lecturer, Department of Oral & Maxillofacial Surgery, Narsinhbhai Patel Dental College , North Gujarat, India .
authors: Shreedevi
authors: S
authors: Bhoi
keywords: Curcumin; Local drug delivery; Periodontitis
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