title: Synchronous oral paracoccidioidomycosis and pulmonary tuberculosis in an immunocompetent patient.
abstract: Paracoccidioidomycosis (PCM) and tuberculosis (TB) are chronic granulomatous infectious diseases, in which the main form of contraction is through inhalation of the microorganism-Paracoccidioides brasiliensis and Mycobacterium tuberculosis. Oral involvement of PCM is observed in up to 70 % of the cases and usually presents clinically as ulcerations with granular surface showing tiny hemorrhagic areas. Oral presentation of TB is rare with prevalence smaller than 0.5 % of all cases. Clinical presentation of oral TB mainly consists of single ulcers with irregular limits and necrotic base. A 70-year-old immunocompetent man presented simultaneously oral PCM and pulmonary TB. Medical history revealed a previous diagnosis of pulmonary TB; however, even under treatment for TB, the patient remained with oral lesions and intense pulmonary fibrosis. The physician requested P. brasiliensis serological analysis, which resulted positive. Although the combination of PCM and TB has been reported in the literature, it is still considered an uncommon condition and their diagnosis may represent a challenge to healthcare professionals because of the similarity between their clinical and radiological presentations.
authors: Piracicaba Dental School, State University of Campinas - UNICAMP, Piracicaba, Brazil.
authors: Ana Carolina
authors: AC
authors: Amorim Pellicioli
authors: Rodrigo
authors: R
authors: Neves-Silva
authors: Alan Roger
authors: AR
authors: Santos-Silva
authors: Pablo Agustin
authors: PA
authors: Vargas
authors: Márcio Ajudarte
authors: MA
authors: Lopes
mesh_terms: D000368:Aged; D006651:Histocytochemistry; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008853:Microscopy; D009059:Mouth Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D010228:Paracoccidioides / Q000302:isolation & purification*; D010229:Paracoccidioidomycosis / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D013902:Radiography, Thoracic; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology
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