title: Clinical study of the application of SPECT, CT, and SPECT/CT for diagnosing rib diseases.
abstract: OBJECTIVE
  To evaluate the practical application of SPECT, CT, and SPECT/CT to the diagnosis of rib diseases, and to compare their accuracies in differentiating benign and malignant rib diseases.
  
  
  METHODS
  SPECT, CT, and SPECT/CT were applied to 237 patients. 190 cases in total, with 305 focal lesions, agreed to clinical follow-up. Statistically significant differences (p < 0.05) were observed among these imaging modalities when their diagnosis agreement ratios (i.e., the percentage of correct diagnoses achieved using a particular imaging modality) were compared.
  
  
  RESULTS
  For the 81 cases that were confirmed to be malignant, the diagnosis agreement ratios of SPECT, CT, and SPECT/CT were 55.56, 76.54, and 92.59 %, respectively, which were significantly different (p < 0.05). For the 97 cases that were confirmed to be benign, the diagnosis agreement ratios of SPECT, CT, and SPECT/CT were 50.52, 83.51, and 92.78 %, respectively. For the benign cases, the diagnosis agreement ratio of SPECT was significantly different (p < 0.05) from those of CT and SPECT/CT, while the diagnosis agreement ratio of CT was not significantly different (p > 0.05) from that of SPECT/CT.
  
  
  CONCLUSIONS
  SPECT/CT fusion imaging yielded significantly improved diagnostic accuracy for rib lesions compared with SPECT or CT alone. SPECT/CT provides markedly more detailed information that is useful for rib lesion diagnosis.
authors: Department of Radiology, The First People's Hospital of Xiaoshan, Hangzhou, 311200, Zhejiang Province, China, duan_shuangmei@126.com.
authors: Runqing
authors: R
authors: Duan
authors: Hongcheng
authors: H
authors: Shi
mesh_terms: D000328:Adult; D000368:Aged; D001847:Bone Diseases / Q000000981:diagnostic imaging*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012272:Ribs / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
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