title: Base-mediated decomposition of amide-substituted furfuryl tosylhydrazones: synthesis and cytotoxic activities of enynyl-ketoamides.
abstract: Base-mediated decomposition of amide-substituted furfuryl tosylhydrazones afforded practical access to novel multifunctionalized enynyl-ketoamides. In addition, furfuryl tosylhydrazones with stable furan rings underwent an interesting tosyl-group migration to form sulfones, which have potential synthetic applications. Some of the obtained enynyl-ketoamides demonstrated good cytotoxicities against human tumor cell lines.
authors: School of Chemistry and Chemical Engineering, South China University of Technology , Guangzhou 510006, P.R. China.
authors: Fanghua
authors: F
authors: Ji
authors: Hui
authors: H
authors: Peng
authors: Xiaoting
authors: X
authors: Zhang
authors: Wenhua
authors: W
authors: Lu
authors: Shubin
authors: S
authors: Liu
authors: Huanfeng
authors: H
authors: Jiang
authors: Bo
authors: B
authors: Liu
authors: Biaolin
authors: B
authors: Yin