title: Utility of endobronchial ultrasound-guided transbronchial needle aspiration in diagnosis of intrathoracic lymphadenopathy in patients with human immunodeficiency virus infection.
abstract: Objective. Intrathoracic lymphadenopathy (LAD) in patients with Human Immunodeficiency Virus (HIV) infection is common, with wide-ranging diagnoses, from benign to malignant causes. Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) is a relatively new technology with established applications in lung cancer, sarcoidosis, and tuberculosis. We sought to find out whether the addition of EBUS-TBNA to the diagnostic algorithm for LAD in HIV patients will reduce the need for mediastinoscopy. Methods. Retrospective chart review of all EBUS-TBNA procedures performed in our centre from August 2008 to December 2012. Results. 513 patients had EBUS-TBNA performed during this period. We identified nine HIV-infected patients who had LAD of unknown cause and underwent EBUS-TBNA. The procedure reduced the need for mediastinoscopy in eight patients (89%). Conclusions. Potential mediastinoscopies can be avoided by utilising EBUS-TBNA in HIV patients with LAD.
authors: Department of Respiratory and Critical Care Medicine, Singapore General Hospital, 20 College Road, Academia, Singapore 169856.
authors: Audrey Yan Yi
authors: AY
authors: Han
authors: Department of Respiratory and Critical Care Medicine, Singapore General Hospital, 20 College Road, Academia, Singapore 169856.
authors: Aik Hau
authors: 0000-0002-7019-4766
authors: AH
authors: Tan
authors: Department of Respiratory and Critical Care Medicine, Singapore General Hospital, 20 College Road, Academia, Singapore 169856.
authors: Mariko Siyue
authors: MS
authors: Koh
mesh_terms: D000328:Adult; D000368:Aged; D044963:Biopsy, Fine-Needle; D001980:Bronchi / Q000000981:diagnostic imaging*; D003710:Demography; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013909:Thorax / Q000473:pathology*; D014463:Ultrasonography
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