title: Hyperemesis gravidarum affects maternal sanity, thyroid hormones and fetal health: a prospective case control study.
abstract: OBJECTIVE
  Hyperemesis gravidarum (HG) is a condition of severe nausea or vomiting accompanied by various complications during pregnancy. In the present study, we aimed to demonstrate the effects of HG on mother and fetus health.
  
  
  METHODS
  Control and case group were arranged from 50 healthy pregnant women and 50 pregnant women with HG. Information about the participant women was gathered with data collection form and Beck's Depression Inventory (BDI) and State Anxiety Inventory (SAI) were administered to the women. Following an abortion or delivery, the data about birth complications and neonatal health were collected. All laboratory results (blood count, thyroid hormones, electrolyte values and biochemical parameters) were gathered from the laboratory information system used in the hospital.
  
  
  RESULTS
  It was found that in the case group, mean postpartum weight, serum hemoglobin, hematocrit and thyroid stimulant hormone levels were lower than control group (p < 0.01). Conversely, case group women have higher T3 and T4 levels than control group (p < 0.01). There was no significant difference between the two groups in terms of intrauterine growth retardation, low birth weight and abortion but it was observed that women with HG had often delivered prematurely. The mean scores of BDI and SAI in the case group were higher than those of control group.
  
  
  CONCLUSIONS
  These results suggested that HG may have adverse effects on both mother and baby's health. Pregnant women with HG should be provided with training and consultancy services and be closely monitored in terms of anemia and thyroid hormones.
authors: Department of Nursing, Health School, Hitit University, 19100, Çorum, Turkey.
authors: Nuriye
authors: N
authors: Buyukkayaci Duman
authors: Oguzhan
authors: O
authors: Ozcan
authors: M Ömer
authors: MÖ
authors: Bostanci
mesh_terms: D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D016022:Case-Control Studies; D003863:Depression / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D005317:Fetal Growth Retardation; D005865:Gestational Age; D006801:Humans; D006939:Hyperemesis Gravidarum / Q000150:complications* / Q000523:psychology; D008423:Maternal Age; D011247:Pregnancy; D047928:Premature Birth / Q000453:epidemiology; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D013963:Thyroid Hormones / Q000097:blood*; D014421:Turkey / Q000453:epidemiology; D016387:Women's Health
chemical_list: D013963:Thyroid Hormones