title: Fabrication and characterization of a multichannel 3D thermopile for chip calorimeter applications.
abstract: Thermal sensors based on thermopiles are some of the most robust and popular temperature sensing technologies across industries and research disciplines. A chip calorimeter with a 3D thermopile layout with a large sensing area and multichannel capacity has been developed, which is highly desired for many applications requiring large reaction chambers or high throughputs, such as biofilm research, drug screening, etc. The performance of the device, including temperature sensitivity and heat power sensitivity, was evaluated. The capability to split the chip calorimeter to multiple channels was also demonstrated, which makes the chip calorimeter very flexible and powerful in many applications.
authors: School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue 639798, Singapore. ycohen@ntu.edu.sg.|Singapore Centre on Environmental Life Sciences and Engineering, Interdisciplinary Graduate School, Nanyang Technological University, 60 Nanyang Drive 637551, Singapore. ycohen@ntu.edu.sg.
authors: Tho Phuoc
authors: TP
authors: Huynh
authors: School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue 639798, Singapore. ylzhang@ntu.edu.sg.
authors: Yilei
authors: Y
authors: Zhang
authors: Singapore Centre on Environmental Life Sciences and Engineering, Interdisciplinary Graduate School, Nanyang Technological University, 60 Nanyang Drive 637551, Singapore. ycohen@ntu.edu.sg.
authors: Cohen
authors: C
authors: Yehuda
mesh_terms: D018441:Biofilms; D002151:Calorimetry / Q000295:instrumentation*; D004353:Drug Evaluation, Preclinical; D006358:Hot Temperature; D006801:Humans
references: Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9517-22
references: 15210951
references: Proc Natl Acad Sci U S A. 2009 Sep 8;106(36):15225-30
references: 19706406
references: Sensors (Basel). 2010;10(10):9369-83
references: 22163413
references: Antimicrob Agents Chemother. 2010 Jan;54(1):312-9
references: 19822705
references: Anal Chem. 2002 May 1;74(9):2190-7
references: 12033326
references: J Microbiol Methods. 2008 Aug;74(2-3):74-81
references: 18502524
references: Biosens Bioelectron. 2004 Jul 15;19(12):1733-43
references: 15142608
references: Sci Rep. 2013 Dec 13;3:3448
references: 24336319
references: Nat Mater. 2003 Aug;2(8):528-31
references: 12883550
references: Appl Microbiol Biotechnol. 2011 Oct;92(1):55-66
references: 21808971
references: Biotechnol J. 2010 Dec;5(12):1339-50
references: 21154672