title: Prolonged antibiotic therapy increases risk of infection after transrectal prostate biopsy: a case report after pancreasectomy and review of the literature.
abstract: Infection due to prostate biopsy afflicted more than 5% of patients and is the most common reason for hospitalization. A large series from US SEER-Medicare reported that men undergoing biopsy were 2.26 times more likely to be hospitalized for infectious complications within 30 days compared with randomly selected controls. The factors predicting a higher susceptibility to infection remain largely unknown but some authors have higlighted in the etiopathogenesis the importance of the augmented prevalence of ciprofloxacin resistant variant of bacteria in the rectum flora. We present one case of sepsis after transrectal prostate biopsy in a patient with history of pancreatic surgery. Based on our experience patients candidated to prostate biopsy with transrectal technique with history of recent major surgery represent an high risk category for infective complication. Also major pancreatic surgery should be consider an high risk category for infection. A transperineal approach and preventive measures (such as rectal swab) should be adopted to reduce biopsy driven infection.
authors: Division of Urology, "Augusto Murri" General Hospital, ASUR Marche, Fermo. guevarmaselli@katamail.com.
authors: Guevar
authors: G
authors: Maselli
authors: Giacomo
authors: G
authors: Tucci
authors: Daniele
authors: D
authors: Mazzaferro
authors: Asim
authors: A
authors: Ettamimi
authors: Giulia
authors: G
authors: Sbrollini
authors: Marco
authors: M
authors: Cordari
authors: Gaetano
authors: G
authors: Donatelli
authors: Andrea Benedetto
authors: AB
authors: Galosi
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001706:Biopsy / Q000009:adverse effects / Q000379:methods; D024881:Drug Resistance, Bacterial; D004927:Escherichia coli Infections / Q000139:chemically induced* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D011183:Postoperative Complications / Q000139:chemically induced* / Q000453:epidemiology; D011467:Prostate / Q000473:pathology*; D012007:Rectum; D018570:Risk Assessment; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents