title: Squamous cell carcinoma arising from a recurrent ischial pressure ulcer: a case report.
abstract: Marjolin's ulcer is the malignant transformation of long-standing chronic pressure ulcers and requires prompt diagnosis and treatment. A 46-year-old man with an 8-year history of traumatic spinal injury with paraplegia presented with a recurrent ischial pressure ulcer. The initial ulcer, which developed 6 years earlier, was a Stage IV sacral ulcer. The wound was debrided and pathology showed epithelial hyperplasia, acanthosis, hyperkatosis accompanied by mild inflammation, and fibrosis without any malignant transformation. The lesion was covered with a fasciocutaneous bipedicled flap. Four years later, the patient presented with a similar ulcer in the same location. Histology showed the presence of a well-differentiated squamous cell carcinoma (SCC). Following a wide excision, the lesion was covered with a gluteal maximal V-Y musculocutaneous advancement flap. At last follow-up 14 months postoperatively, there was no evidence of recurrence or metastatic disease. Clinicians must be aware of known risk factors for the development of SCC.
authors: changyi@office365.ndmctsgh.edu.tw.
authors: Chang-Yi
authors: CY
authors: Chou
authors: Zheng-Yi
authors: ZY
authors: Huang
authors: Hao-Yu
authors: HY
authors: Chiao
authors: Chi-Yu
authors: CY
authors: Wang
authors: Yu-Shan
authors: YS
authors: Sun
authors: Shyi-Gen
authors: SG
authors: Chen
authors: Tim-Mon
authors: TM
authors: Chen
authors: Shun-Cheng
authors: SC
authors: Chang
mesh_terms: D002081:Buttocks / Q000098:blood supply / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010264:Paraplegia / Q000150:complications / Q000451:nursing; D003668:Pressure Ulcer / Q000150:complications*; D012878:Skin Neoplasms / Q000601:surgery