title: Comparison of the effects of various airway devices on hemodynamic response and QTc interval in rabbits under general anesthesia.
abstract: In this study, we aimed to compare the effects of various airway devices on QTc interval in rabbits under general anesthesia. The subjects were randomly separated into four groups: Group ETT, Group LMA, Group PLA, Group V-gel. Baseline values and hearth rate, mean arterial pressure and ECG was obtained at the 1st, 5th and 30th minutes after administration of anesthesia and placement of airway device and, QTc interval was evaluated. Difference was observed between ET group and V-gel group in the 5th minute mean arterial pressure values (p < 0.05). It was observed that QTc intervals at the 1st and 5th minute in the ET group significantly increased when compared with the other groups (p < 0.05). Again, it was observed that QTc interval of ET group at the 15th and 30th minute was longer when compared with PLA and V-gel groups (p < 0.05). It was also observed that QTc interval of LMA Group at the 5th minute after intubation significantly increased when compared with V-gel group (p < 0.05). It was observed that HR values of ETT group at the 1st, 5th and 15th minutes after intubation increased with regards to PLA and V-gel groups (p < 0.05). It was determined that the 30th minute hearth rate of ETT group was higher when compared to V-gel group (p < 0.05).
  
  
  CONCLUSIONS
  In our study we observed that V-gel Rabbit affected both hemodynamic response and QT interval less than other airway devices.
authors: Department of Anesthesiology and Reanimation, Faculty of Medicine, Canakkale Onsekiz Mart University, 17100, Canakkale, Turkey. huseyintoman@comu.edu.tr.
authors: Huseyin
authors: H
authors: Toman
authors: Department of Anesthesiology and Reanimation, Faculty of Medicine, Canakkale Onsekiz Mart University, 17100, Canakkale, Turkey.
authors: Mesut
authors: M
authors: Erbas
authors: Department of Anesthesiology and Reanimation, Faculty of Medicine, Canakkale Onsekiz Mart University, 17100, Canakkale, Turkey.
authors: Hasan
authors: H
authors: Sahin
authors: Department of Anesthesiology and Reanimation, Faculty of Medicine, Canakkale Onsekiz Mart University, 17100, Canakkale, Turkey.
authors: Hasan Ali
authors: HA
authors: Kiraz
authors: Department of Physiology, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey.
authors: Metehan
authors: M
authors: Uzun
authors: Department of Physiology, Faculty of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey.
authors: Mehmet Akif
authors: MA
authors: Ovali
mesh_terms: D000768:Anesthesia, General / Q000295:instrumentation*; D000818:Animals; D004562:Electrocardiography; D004867:Equipment Design; D006339:Heart Rate; D006439:Hemodynamics; D007442:Intubation, Intratracheal / Q000295:instrumentation*; D017214:Laryngeal Masks; D023421:Models, Animal; D011817:Rabbits
keywords: Cobra PLA; Endotracheal intubation; Hemodynamic response; Laryngeal mask airway; QTc; Supraglottic airway; V-gel Rabbit
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