title: Mixed myoclonic-absence status epilepticus in juvenile myoclonic epilepsy.
abstract: Myoclonic status epilepticus or mixed absence-myoclonic status is uncommon in juvenile myoclonic epilepsy (JME), often precipitated by sleep deprivation, withdrawal of medication, or inadequate antiepileptic drugs (Thomas et al., 2006; Crespel et al., 2013). Such episodes respond well to benzodiazepines or valproate (Crespel et al., 2013). We present the video-EEG of a 24-year-old woman with JME and bipolar disorder. She had a confusional state five days after withdrawal of clonazepam (14 mg/d) and introduction of oxazepam (200 mg/d), followed by catatonic stupor with subtle myoclonus of the face and the arms. The EEG showed absence status (figures 1, 2), which stopped after IV injection of clonazepam (1 mg) (figure 3). Consciousness returned to normal [Published with video sequence and figures (1)].
authors: Epilepsy Unit, Hôpital Gui de Chauliac, Montpellier Research Unit URCMA (Unité de recherche sur les comportements et mouvements anormaux), INSERM, U661, Montpellier, France.
authors: Philippe
authors: P
authors: Gélisse
authors: Epilepsy Unit, Hôpital Gui de Chauliac, Montpellier Research Unit URCMA (Unité de recherche sur les comportements et mouvements anormaux), INSERM, U661, Montpellier, France.
authors: Arielle
authors: A
authors: Crespel
mesh_terms: D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000150:complications; D002389:Catatonia / Q000209:etiology; D002998:Clonazepam / Q000009:adverse effects / Q000627:therapeutic use; D004569:Electroencephalography; D004831:Epilepsies, Myoclonic / Q000209:etiology*; D005260:Female; D006801:Humans; D020190:Myoclonic Epilepsy, Juvenile / Q000150:complications*; D010076:Oxazepam / Q000009:adverse effects / Q000627:therapeutic use; D013226:Status Epilepticus / Q000209:etiology*; D014635:Valproic Acid / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D000927:Anticonvulsants; D002998:Clonazepam; D014635:Valproic Acid; D010076:Oxazepam
keywords: absence seizure; juvenile myoclonic epilepsy; status epilepticus