title: On the relationship between negative affective priming and prefrontal cognitive control mechanisms.
abstract: Although several studies have examined inhibition of affective stimuli, valence-dependent cognitive control effects remain poorly understood. Behavioural and functional imaging (functional magnetic resonance imaging) data were collected from 17 healthy participants to examine neural correlates of the Negative Affective Priming (NAP) task. We created relative ratio scores considering the reaction times of prime trials in order to assess the amount of interference after the presentation of negative and positive distracter words. Behavioural results showed an attenuated NAP effect for negative distracters compared to neutral stimuli. Furthermore, priming negative distracters generated more interference by reacting to the probe target than positive distracters. Neuroimaging data revealed a stronger prefrontal activation during negative NAP trials compared to positive NAP and neutral control trials, which was reflected in a heightened activation of superior and middle frontal gyrus as well as parietal cortex. The findings show the impact of negative distracters on prefrontal response, contributing to the understanding of NAP effects in healthy subjects.
authors: a Department of Clinical Psychology and Psychotherapy , Institute of Psychology, University of Heidelberg , Heidelberg , Germany.
authors: Rosalux
authors: R
authors: Falquez
authors: a Department of Clinical Psychology and Psychotherapy , Institute of Psychology, University of Heidelberg , Heidelberg , Germany.
authors: Simone
authors: S
authors: Lang
authors: a Department of Clinical Psychology and Psychotherapy , Institute of Psychology, University of Heidelberg , Heidelberg , Germany.|b Department of Cognitive and Clinical Neuroscience , Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University , Mannheim , Germany.
authors: Ramona
authors: R
authors: Dinu-Biringer
authors: b Department of Cognitive and Clinical Neuroscience , Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University , Mannheim , Germany.
authors: Frauke
authors: F
authors: Nees
authors: a Department of Clinical Psychology and Psychotherapy , Institute of Psychology, University of Heidelberg , Heidelberg , Germany.
authors: Elisabeth
authors: E
authors: Arens
authors: c Institute of Medical Psychology and Behavioral Neurobiology , University of Tuebingen , Tuebingen , Germany.
authors: Boris
authors: B
authors: Kotchoubey
authors: d Department of Medical Physics in Radiology , German Cancer Research Center (DKFZ) , Heidelberg , Germany.
authors: Moritz
authors: M
authors: Berger
authors: a Department of Clinical Psychology and Psychotherapy , Institute of Psychology, University of Heidelberg , Heidelberg , Germany.
authors: Sven
authors: S
authors: Barnow
mesh_terms: D000328:Adult; D000339:Affect / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D005260:Female; D059907:Functional Neuroimaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010296:Parietal Lobe / Q000502:physiology; D010775:Photic Stimulation; D017397:Prefrontal Cortex / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D060865:Repetition Priming / Q000502:physiology*; D055815:Young Adult
keywords: Facilitation effect; Negative affective priming; Negativity bias; Selective attention