title: Sexual Function in Patients Operated on for Bladder Exstrophy and Epispadias.
abstract: OBJECTIVE
  Bladder exstrophy and epispadias complex is a rare congenital malformation that may have detrimental effects on sexual function. We evaluated sexual function of patients with bladder exstrophy and epispadias complex using validated questionnaires and compared the results with age matched controls.
  
  
  METHODS
  Patients with bladder exstrophy and epispadias complex treated between 1956 and 1992 were identified from our hospital operative database. A total of 63 patients were mailed questionnaires up to 3 times, resulting in 32 replies (51%). Men were mailed the International Index of Erectile Function-15 questionnaire and women were mailed the Female Sexual Function Index questionnaire, and all patients were asked auxiliary questions regarding children, satisfaction with external genitalia and urinary continence.
  
  
  RESULTS
  There were no differences in sexual function between sexually active men with bladder exstrophy and epispadias complex and age matched controls on different erectile function domain scores according to the International Index of Erectile Function-15 questionnaire. The Female Sexual Function Index questionnaire among women yielded comparable results on different domain scores, except for median total score, which was higher in patients (33.6, IQR 29.4 to 34.9) than in controls (30.1, IQR 26.4 to 32.4, p = 0.049), suggesting better sexual function in patients with bladder exstrophy and epispadias complex. A greater proportion of patients with bladder exstrophy and epispadias complex had not become sexually active, compared to controls (35% vs 11%, p = 0.008). Patients with bladder exstrophy and epispadias complex were less likely to have children than controls (22% vs 45%, p = 0.021).
  
  
  CONCLUSIONS
  Men and women with bladder exstrophy and epispadias complex had good long-term outcomes on erectile and general sexual function tests. However, there is a likelihood that these individuals start their sexual life later than the general population, and fewer have children compared to controls.
authors: Department of Pediatric Surgery, Children's Hospital, University of Helsinki, Helsinki, Finland; Department of Psychology and Logopedics, Åbo Akademi University, Turku (PS), Finland. Electronic address: jasasu@yahoo.com.
authors: Janne S
authors: JS
authors: Suominen
authors: Department of Pediatric Surgery, Children's Hospital, University of Helsinki, Helsinki, Finland; Department of Psychology and Logopedics, Åbo Akademi University, Turku (PS), Finland.
authors: Pekka
authors: P
authors: Santtila
authors: Department of Pediatric Surgery, Children's Hospital, University of Helsinki, Helsinki, Finland; Department of Psychology and Logopedics, Åbo Akademi University, Turku (PS), Finland.
authors: Seppo
authors: S
authors: Taskinen
mesh_terms: D000328:Adult; D001746:Bladder Exstrophy / Q000150:complications / Q000601:surgery*; D004842:Epispadias / Q000150:complications / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D019529:Sexuality / Q000502:physiology*; D011795:Surveys and Questionnaires
keywords: bladder exstrophy; bladder exstrophy and epispadias complex; epispadias; physiological; sexual dysfunction