title: Predicting falls in elderly patients with chronic pain and other chronic conditions.
abstract: BACKGROUND
  The aim was to identify fall predictors in elderly suffering from chronic pain (CP) and to test their applicability among patients with other chronic conditions.
  
  
  METHODS
  1,379 non-institutionalized patients aged 65 years and older who were suffering from CP (S.AGE CP sub-cohort) were monitored every 6 months for 1 year. Socio-demographic, clinical and pain data and medication use were assessed at baseline for the association with falls in the following year. Falls were assessed retrospectively at each study visit. Logistic regression analyses were performed to identify fall predictors. The derived model was applied to two additional S.AGE sub-cohorts: atrial fibrillation (AF) (n = 1,072) and type-2 diabetes mellitus (T2DM) (n = 983).
  
  
  RESULTS
  Four factors predicted falls in the CP sub-cohort: fall history (OR: 4.03, 95 % CI 2.79-5.82), dependency in daily activities (OR: 1.81, 95 % CI 1.27-2.59), age ≥75 (OR: 1.53, 95 % CI 1.04-2.25) and living alone (OR: 1.73, 95 % CI 1.24-2.41) (Area Under the Curve: AUC = 0.71, 95 % CI 0.67-0.75). These factors were relevant in AF (AUC = 0.71, 95 % CI 0.66-0.75) and T2DM (AUC = 0.67, 95 % CI 0.59-0.73) sub-cohorts. Fall predicted probability in CP, AF and T2DM sub-cohorts increased from 7, 7 and 6 % in patients with no risk factors to 59, 66 and 45 % respectively, in those with the four predictors. Fall history was the strongest predictor in the three sub-cohorts.
  
  
  CONCLUSIONS
  Fall history, dependency in daily activities, age ≥75 and living alone are independent fall predictors in CP, AF and T2DM patients.
authors: Pharmacology Department, Paris-Sud Faculty of Medicine, AP-HP, Bicêtre Hospital, Paris-Sud University, 63, rue Gabriel Péri, 94276, Le Kremlin-Bicêtre, France. didafarma@yahoo.com.
authors: Aida
authors: A
authors: Lazkani
authors: Pharmacology Department, Paris-Sud Faculty of Medicine, AP-HP, Bicêtre Hospital, Paris-Sud University, 63, rue Gabriel Péri, 94276, Le Kremlin-Bicêtre, France.
authors: Tiba
authors: T
authors: Delespierre
authors: Endocrinology Department, Bégin Hospital, Saint-Mandé, France.
authors: Bernard
authors: B
authors: Bauduceau
authors: ORPEA/CLINEA, Puteaux, France.
authors: Linda
authors: L
authors: Benattar-Zibi
authors: Rheumatology Department, Limoges University Hospital, Limoges, France.
authors: Philippe
authors: P
authors: Bertin
authors: Clinical Gerontology, Nantes University Hospital, Nantes, France.
authors: Gilles
authors: G
authors: Berrut
authors: Paris-Sud Faculty of Medicine, Psychiatry Department, Bicêtre University Hospital, AP-HP, INSERM U 669, Paris-Sud University, Le Kremlin-Bicêtre, France.
authors: Emmanuelle
authors: E
authors: Corruble
authors: HEGP, Coronary Diseases, Paris, France.
authors: Nicolas
authors: N
authors: Danchin
authors: Cardiovascular Functional Exploration, Louis Pradel Hospital, Hospices Civils de Lyon, Bron, France.
authors: Geneviève
authors: G
authors: Derumeaux
authors: Internal Medicine, Geriatrics and Therapeutics, Saint Julien University Hospital, Rouen University, Rouen, France.
authors: Jean
authors: J
authors: Doucet
authors: Paris-Sud Faculty of Medicine, Biostatistics Department, AP-HP, Paul Brousse Hospital, INSERM U 669, Paris-Sud University, Le Kremlin-Bicêtre, France.
authors: Bruno
authors: B
authors: Falissard
authors: National Gerontology Foundation, Paris Descartes University, Paris, France.
authors: Francoise
authors: F
authors: Forette
authors: AP-HP, Broca Hospital, Geriatrics Department, Paris Descartes University, EA 4468, Paris, France.
authors: Olivier
authors: O
authors: Hanon
authors: Lille University Hospital, Lille Nord de France University, UDSL, EA 1046, Lille, France.
authors: Florence
authors: F
authors: Pasquier
authors: Endocrinology, Diabetes and Nutrition-Related Diseases (NUDE Unit), Strasbourg University Hospital, and the European Centre for the Study of Diabetes (CeeD), Strasbourg University, Strasbourg, France.
authors: Michel
authors: M
authors: Pinget
authors: General Practice Department, Paris-Sud Faculty of Medicine, Paris-Sud University, Le Kremlin-Bicêtre, France.
authors: Rissane
authors: R
authors: Ourabah
authors: Pharmacology Department, Paris-Sud Faculty of Medicine, AP-HP, Bicêtre Hospital, Paris-Sud University, 63, rue Gabriel Péri, 94276, Le Kremlin-Bicêtre, France.
authors: Celine
authors: C
authors: Piedvache
authors: Pharmacology Department, Paris-Sud Faculty of Medicine, AP-HP, Bicêtre Hospital, Paris-Sud University, 63, rue Gabriel Péri, 94276, Le Kremlin-Bicêtre, France.
authors: Laurent
authors: L
authors: Becquemont
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control / Q000706:statistics & numerical data; D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000453:epidemiology*; D015984:Causality; D059350:Chronic Pain / Q000175:diagnosis / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D015577:Geriatric Assessment / Q000379:methods; D006801:Humans; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors
keywords: Chronic pain; Elderly; Fall; Risk factor