title: Cooperative catalysis: enantioselective propargylic alkylation of propargylic alcohols with enecarbamates using ruthenium/phosphoramide hybrid catalysts.
abstract: The diastereo- and enantioselective propargylic alkylation of propargylic alcohols with E-enecarbamates in the presence of a catalytic amount of thiolate-bridged diruthenium complexes bearing an optically active phosphoramide moiety gives the corresponding propargylic alkylated products (up to 97 % ee).
authors: Institute of Engineering Innovation, School of Engineering, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113-8656 (Japan).
authors: Yasushi
authors: Y
authors: Senda
authors: Kazunari
authors: K
authors: Nakajima
authors: Yoshiaki
authors: Y
authors: Nishibayashi
keywords: alkynes; asymmetric catalysis; organocatalyst; ruthenium; synthetic methods