title: First MRI application of an active breathing coordinator.
abstract: A commercial active breathing coordinator (ABC) device, employed to hold respiration at a specific level for a predefined duration, was successfully adapted for magnetic resonance imaging (MRI) use for the first time. Potential effects of the necessary modifications were assessed and taken into account. Automatic MR acquisition during ABC breath holding was achieved. The feasibility of MR-ABC thoracic and abdominal examinations together with the advantages of imaging in repeated ABC-controlled breath holds were demonstrated on healthy volunteers. Five lung cancer patients were imaged under MR-ABC, visually confirming the very good intra-session reproducibility of organ position in images acquired with the same patient positioning as used for computed tomography (CT). Using identical ABC settings, good MR-CT inter-modality registration was achieved. This demonstrates the value of ABC, since application of T1, T2 and diffusion weighted MR sequences provides a wider range of contrast mechanisms and additional diagnostic information compared to CT, thus improving radiotherapy treatment planning and assessment.
authors: CR-UK Cancer Imaging Centre, Institute of Cancer Research London and Royal Marsden Hospital, London, UK.
authors: E
authors: E
authors: Kaza
authors: R
authors: R
authors: Symonds-Tayler
authors: D J
authors: DJ
authors: Collins
authors: F
authors: F
authors: McDonald
authors: H A
authors: HA
authors: McNair
authors: E
authors: E
authors: Scurr
authors: D-M
authors: DM
authors: Koh
authors: M O
authors: MO
authors: Leach
mesh_terms: D062485:Breath Holding; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008297:Male; D056888:Patient Positioning; D055425:Respiratory-Gated Imaging Techniques / Q000295:instrumentation / Q000379:methods*; D014159:Transducers
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