title: [Acute myocardial infarction as Eosinophilic granulomatosis with polyangiitis (formerly Churg Strauss syndrome) initial presentation].
abstract: Eosinophilic granulomatosis with polyangiitis is a rare primary vasculitic disease characterized by hypereosinophilia, late onset asthma and extravascular eosinophil granulomas. We report a case presented initially with acute myocardial infarction which later only proceed with asthma, skin manifestations and peripheral neuropathy. Laboratory parameters showed hypereosinohpilia with negative perinuclear pattern of antineutrophil cytoplasmic autoantibodies (p-ANCA). Skin biopsy showed leucocytoclastic vasculitis with eosinophilic infiltration while coronary angiography was normal. The patient's symptoms improved with IV methylprednisolone, pulse cyclophosphamide and azathioprine.
authors: Divisão de Reumatologia, Departamento de Medicina, Hospital Raja Permaisuri Bainun Ipoh, Perak, Malásia.
authors: Wahinuddin
authors: W
authors: Sulaiman
authors: Divisão de Reumatologia, Departamento de Medicina, Hospital Raja Permaisuri Bainun Ipoh, Perak, Malásia. Electronic address: ongps@hotmail.com.
authors: Ong Ping
authors: OP
authors: Seung
authors: Departamento de Patologia, Hospital Raja Permaisuri Bainun Ipoh, Perak, Malásia.
authors: Sabariah Mohd
authors: SM
authors: Noor
mesh_terms: D015267:Churg-Strauss Syndrome / Q000150:complications / Q000175:diagnosis*; D014890:Granulomatosis with Polyangiitis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology*
keywords: Asma; Asthma; Churg Strauss syndrome; Eosinophilic granulomatosis with polyangiitis; Granulomatose eosinofílica com poliangiite; Hipereosinofilia; Hypereosinophilia; Infarto do miocárdio; Myocardial infarction; Síndrome de Churg Strauss