title: Antimicrobial and Antioxidant Properties of Satureja Montana L. and S. Subspicata Vis. (Lamiaceae).
abstract: Satureja montanaL. and S. subspicata Vis. (Lamiaceae) are used for centuries in traditional medicine of Balcanic people in the healing of the lymphatic nodule and respiratory system inflammation. In this paper the amount of total phenols and flavonoids (analyzed by UV/Vis spectrophotometry), phenolic compounds profile (analyzed by HPLC), antimicrobial and antioxidant activities were studied in samples collected in seven per species populations of S. montanaand S. subspicatain Croatia. Eight phenolic compounds (rutin, quercetin, caffeic, p-coumaric, ellagic, protocatehuic, rosmarinic, and syringic acid) were identified and quantified using HPLC in methanolic and ethanolic extracts. Results showed that both species contained polyphenolics and other antioxidant compounds with chelating and radical-scavenging properties. The extracts prepared from both species showed broad spectrum of antimicrobial activity on in vitrotested microbial species (Staphylococcus aureus, Escherichia coli, Candida albicans, C. dubliniensis, C. krusei, C. glabrata, C. parapsilosis, and Microsporum gypseum).
authors: Faculty of Pharmacy and Biochemistry University of Zagreb, A. Kovačića 1, HR-10000 Zagreb, Croatia. dkremer@pharma.hr.
authors: Dario
authors: D
authors: Kremer
authors: Iztok Jože
authors: IJ
authors: Košir
authors: Marijana Zovko
authors: MZ
authors: Končić
authors: Andreja
authors: A
authors: Čerenak
authors: Tanja
authors: T
authors: Potočnik
authors: Siniša
authors: S
authors: Srečec
authors: Marko
authors: M
authors: Randić
authors: Ivan
authors: I
authors: Kosalec
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D017523:Croatia; D005419:Flavonoids / Q000032:analysis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010636:Phenols / Q000032:analysis* / Q000494:pharmacology; D010936:Plant Extracts / Q000032:analysis / Q000494:pharmacology; D031362:Satureja / Q000737:chemistry* / Q000145:classification
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D005419:Flavonoids; D010636:Phenols; D010936:Plant Extracts