title: Structural analysis of different incision sizes and stromal hydration in cataract surgery using anterior segment optical coherence tomography.
abstract: OBJECTIVE
  To analyze healing changes of corneal wounds of different corneal incision sizes with or without stromal hydration in cataract surgery using anterior segment optical coherence tomography.
  
  
  METHODS
  Cataract surgeries were performed by a single surgeon and 2.2- and 2.8-mm corneal incisions were made using a diamond blade (ME-759; Meyco, Biel-Bienne, Swiss). Patients were divided into four groups according to incision size (2.2 and 2.8 mm), and with/without stromal hydration. Fifteen eyes were assigned to each group and incision wounds were measured using anterior segment optical coherence tomography at 2 hours, 1 day, 1 week, 1 month, and 3 months postoperatively. Corneal thickness, incision length and incision angle were measured and existence of epithelial, endothelial gaping and Descemet's membrane detachment was evaluated.
  
  
  RESULTS
  Incision thickness was greater in the group with stromal hydration than in the group without on operation day (p < 0.05). Stromal hydration exerted greater influence in the 2.2-mm incision group than in the 2.8-mm incision group. Corneal thickness decreased more rapidly in the stromal hydration group than in the group with no hydration (p = 0.022). Endothelial gaping was greater in the 2.2-mm incision group than in the 2.8-mm incision group 1 day, 1 month, and 3 months after surgery (p = 0.035, p = 0.009, and p = 0.008, respectively). No other statistical significance was observed between the two groups (2.2 and 2.8 mm) during follow-up regarding corneal thickness, epithelial gaping and Descemet's membrane detachment.
  
  
  CONCLUSIONS
  Corneal wounds with a smaller incision could be more vulnerable to external stimuli such as stromal hydration and are less stable than those with a larger incision.
authors: Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
authors: Jong-Wook
authors: JW
authors: Bang
authors: Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
authors: Jong-Hyun
authors: JH
authors: Lee
authors: Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
authors: Jin-Hyoung
authors: JH
authors: Kim
authors: Department of Ophthalmology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
authors: Do-Hyung
authors: DH
authors: Lee
mesh_terms: D000368:Aged; D000869:Anterior Eye Segment; D002387:Cataract Extraction / Q000379:methods*; D003319:Corneal Stroma / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013529:Surgical Wound Dehiscence / Q000175:diagnosis / Q000517:prevention & control*; D041623:Tomography, Optical Coherence / Q000379:methods*; D014945:Wound Healing
keywords: Corneal pachymetry; Corneal stroma; Wounds and injuries
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