title: A new turn on Pd(2+)-specific fluorescence probe and its use as an imaging reagent for cellular uptake in Hct116 cells.
abstract: A new coumarin-rhodamine conjugate is used as a specific probe for Pd(2+) ions and this could even delineate Pd(II) from Pd(0) or Pd(IV) in aqueous buffer medium (pH ∼ 7). Laser confocal microscopic studies reveal that efficient cellular internalization of this reagent helps in imaging the cellular uptake of Pd(2+) as low as 0.1 ppm in Hct 116 cells. This reagent could even be used for estimation of Pd(2+) in human urine samples.
authors: Organic Chemistry Division, CSIR-National Chemical Laboratory, Pune-411008, India. a.das@ncl.res.in.
authors: Upendar
authors: U
authors: Reddy G
authors: Firoj
authors: F
authors: Ali
authors: Nandaraj
authors: N
authors: Taye
authors: Samit
authors: S
authors: Chattopadhyay
authors: Amitava
authors: A
authors: Das
mesh_terms: D003374:Coumarins / Q000737:chemistry* / Q000378:metabolism; D005456:Fluorescent Dyes / Q000032:analysis* / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D045325:HCT116 Cells; D006801:Humans; D007854:Lead / Q000652:urine*; D012235:Rhodamines / Q000737:chemistry* / Q000378:metabolism
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes; D012235:Rhodamines; D007854:Lead; C030123:coumarin