title: Case report of vertebral osteomyelitis and mycotic abdominal aortic aneurysm caused by Scedosporium apiospermum in a lung transplant patient with cystic fibrosis.
abstract: Cystic fibrosis patients are frequently plagued by infections, often with unusual or hardy organisms. Their infections are only complicated by transplantation. In this report, we review the case of a young woman who had a double lung transplant secondary to cystic fibrosis who developed a lumbar osteomyelitis/discitis several years after transplantation. After treatment, she went on to develop a mycotic abdominal aortic aneurysm. The patient underwent thoracic and abdominal aortic replacement, and histopathology revealed Scedosporium apiospermum infection. The patient recovered well from surgery and was discharged home on long-term antifungal therapy. This represents the first reported case of S apiospermum mycotic aneurysm in a lung transplant patient, and possibly the largest number and longest duration of S apiospermum infections reported in a single patient.
authors: Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
authors: S
authors: S
authors: Thomson
authors: Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
authors: K
authors: K
authors: Alibhai
authors: Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
authors: G
authors: G
authors: Winkelaar
authors: Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
authors: D
authors: D
authors: Lien
authors: Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
authors: K
authors: K
authors: Halloran
authors: Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
authors: A
authors: A
authors: Kapasi
authors: Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. Electronic address: jw5@ualberta.ca.
authors: J
authors: J
authors: Weinkauf
mesh_terms: D000293:Adolescent; D000785:Aneurysm, Infected / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D017544:Aortic Aneurysm, Abdominal / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D003550:Cystic Fibrosis / Q000601:surgery*; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae; D016040:Lung Transplantation; D010019:Osteomyelitis / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D021681:Scedosporium; D013904:Thoracic Vertebrae; D055815:Young Adult