title: Irciniastatin A, a pederin-type translation inhibitor, promotes ectodomain shedding of cell-surface tumor necrosis factor receptor 1.
authors: Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Kyoto, Japan.
authors: Seiya
authors: S
authors: Hirano
authors: Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Kyoto, Japan.
authors: Hue Tu
authors: 0000000155711908
authors: HT
authors: Quach
authors: Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
authors: Tsubasa
authors: T
authors: Watanabe
authors: Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
authors: Naoki
authors: N
authors: Kanoh
authors: Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
authors: Yoshiharu
authors: Y
authors: Iwabuchi
authors: Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Japan.
authors: Takeo
authors: T
authors: Usui
authors: Department of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Kyoto, Japan.
authors: Takao
authors: T
authors: Kataoka
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D002277:Carcinoma / Q000188:drug therapy* / Q000378:metabolism; D045744:Cell Line, Tumor; D002462:Cell Membrane / Q000187:drug effects* / Q000378:metabolism; D002467:Cell Nucleus / Q000187:drug effects / Q000378:metabolism; D002470:Cell Survival / Q000187:drug effects; D003374:Coumarins / Q000494:pharmacology*; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D006801:Humans; D018799:Intercellular Adhesion Molecule-1 / Q000235:genetics / Q000378:metabolism; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D008970:Molecular Weight; D009363:Neoplasm Proteins / Q000235:genetics / Q000378:metabolism; D009994:Osmolar Concentration; D014176:Protein Biosynthesis / Q000187:drug effects; D011500:Protein Synthesis Inhibitors / Q000494:pharmacology*; D021381:Protein Transport / Q000187:drug effects; D059748:Proteolysis / Q000187:drug effects; D047888:Receptors, Tumor Necrosis Factor, Type I / Q000378:metabolism*; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; D003374:Coumarins; C573420:ICAM1 protein, human; D009363:Neoplasm Proteins; D011500:Protein Synthesis Inhibitors; D047888:Receptors, Tumor Necrosis Factor, Type I; C498383:psymberin; D018799:Intercellular Adhesion Molecule-1
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