title: Safety, efficacy and reliability of 180-W GreenLight laser technology for prostate vaporization: review of the literature.
abstract: OBJECTIVE
  The aim of this study is to investigate the efficacy and safety of 180-W XPS GreenLight laser technology for photoselective prostate vaporization.
  
  
  METHODS
  A systematic search of the electronic databases was performed. Inclusion criteria were: full-text peer-reviewed journal article, with original data analysis that evaluates the feasibility and the outcome only of 180-W XPS GL laser system. Data at baseline and during follow-up have been taken into account. Intra-operative and postoperative (functional results and complications) data were collected and analyzed.
  
  
  RESULTS
  We found 165 articles in our research, among which only nine articles were selected (total 991 patients). A certain grade of variability is present in all the studies in terms of scientific design, sample size and methods of reporting functional results and complications. Nevertheless, a homogenous benefit for patients in terms of symptom score improvement, post-void residual volume reduction and urinary max flow rate improvement was shown. According to Clavien-Dindo classification, 292 (83.7%) adverse events were recorded ≤ grade 2. Adverse events ≥ grade 3 were 57 (16.3%), among which bleeding, urinary retention and residual obstructive tissue represented the wide majority. No mortality was reported. Male sexual function was poorly investigated.
  
  
  CONCLUSIONS
  The 180-W XPS GL laser technique is feasible and safe, with a remarkable clinical benefit. Long-term evidence on outcomes and complications are suitable even in the sphere of male sexuality.
authors: Urology Department, "G. D'Annunzio" University, Chieti, Italy.
authors: Pietro
authors: P
authors: Castellan
authors: Roberto
authors: R
authors: Castellucci
authors: Luigi
authors: L
authors: Schips
authors: Luca
authors: L
authors: Cindolo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects* / Q000379:methods*; D059411:Lower Urinary Tract Symptoms / Q000209:etiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000601:surgery; D011468:Prostatectomy / Q000009:adverse effects* / Q000379:methods*; D011470:Prostatic Hyperplasia / Q000150:complications; D015203:Reproducibility of Results; D016896:Treatment Outcome; D001748:Urinary Bladder Neck Obstruction / Q000209:etiology / Q000601:surgery
references: J Urol. 2015 Feb;193(2):570-8
references: 25219699
references: Eur Urol. 2014 May;65(5):931-42
references: 24331152
references: Eur Urol. 2012 Apr;61(4):783-95
references: 22285403
references: Yonsei Med J. 2008 Apr 30;49(2):189-99
references: 18452253
references: ANZ J Surg. 2012 May;82(5):334-7
references: 22507245
references: Eur Urol. 2009 Jun;55(6):1345-57
references: 19361906
references: Int Urol Nephrol. 2012 Apr;44(2):359-64
references: 21779921
references: Prostate Int. 2013;1(1):42-5
references: 24223401
references: World J Urol. 2014 Apr;32(2):539-44
references: 24072009
references: Actas Urol Esp. 2014 Jul-Aug;38(6):373-7
references: 24332528
references: Lasers Med Sci. 2015 Jan;30(1):317-23
references: 25274195
references: Lasers Surg Med. 2013 Jan;45(1):28-33
references: 23280439
references: Urology. 2013 Apr;81(4):853-8
references: 23414692
references: Urology. 2000 Nov 1;56(5 Suppl 1):3-6
references: 11074195
references: Eur Urol. 2012 Mar;61(3):600-7
references: 22153927
references: J Urol. 2000 Jun;163(6):1730-3
references: 10799170
references: Eur Urol. 2012 Feb;61(2):341-9
references: 22074761
references: Eur Urol. 2010 Aug;58(2):207-11
references: 20466480
references: J Endourol. 2014 Jan;28(1):73-8
references: 23992242
references: Can J Urol. 2011 Oct;18(5):5918-26
references: 22018158
references: Eur Urol. 2013 Jul;64(1):118-40
references: 23541338
references: Curr Urol Rep. 2011 Aug;12(4):261-4
references: 21656206