title: Congenital atresia of the inferior vena cava and antithrombin III deficiency in a young adult: compounding risk factors for deep vein thrombosis.
abstract: Atresia, or absence, of the inferior vena cava (AIVC) is a rare, usually fortuitous finding on advanced imaging that predisposes patients to deep venous thrombosis (DVT). In young adults who lack predisposing risk factors but nonetheless develop extensive or bilateral DVTs, AIVC should be considered. We describe a case of a previously healthy 17-year-old male patient who developed an extensive renal vein thrombus due to the absence of the superior portion of his IVC compounded with previously undiagnosed antithrombin III deficiency. We discuss the diagnosis and management of this complicated condition.
authors: University of California, Irvine, Orange, California, USA.
authors: Laura
authors: L
authors: Muscianese
authors: University of California, Irvine, Orange, California, USA.
authors: Ronald R
authors: RR
authors: Seese
authors: University of California, Irvine, Orange, California, USA.
authors: William
authors: W
authors: Graham
authors: University of California, Irvine, Orange, California, USA.
authors: James H
authors: JH
authors: Williams
mesh_terms: D000293:Adolescent; D020152:Antithrombin III Deficiency / Q000150:complications*; D006801:Humans; D008297:Male; D012082:Renal Veins / Q000473:pathology*; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D014652:Vascular Diseases / Q000150:complications* / Q000151:congenital; D014682:Vena Cava, Inferior / Q000002:abnormalities*; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000209:etiology
references: J Vasc Surg. 2006 Oct;44(4):820-7
references: 16926084
references: J Cardiovasc Med (Hagerstown). 2008 Jan;9(1):101-4
references: 18268431
references: J Vasc Interv Radiol. 2011 Jun;22(6):801-5
references: 21459610
references: Ann Vasc Surg. 2011 Jul;25(5):697.e1-4
references: 21724109