title: Nickel-catalyzed selective oxidative radical cross-coupling: an effective strategy for inert Csp3-H functionalization.
abstract: An effective strategy for inert Csp(3)-H functionalization through nickel-catalyzed selective radical cross-couplings was demonstrated. Density functional theory calculations were conducted and strongly supported the radical cross-coupling pathway assisted by nickel catalyst, which was further confirmed by radical-trapping experiments. Different arylborates including arylboronic acids, arylboronic acid esters and 2,4,6-triarylboroxin were all good coupling partners, generating the corresponding Csp(3)-H arylation products in good yields.
authors: College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072, PR China.
authors: Dong
authors: D
authors: Liu
authors: Yuxiu
authors: Y
authors: Li
authors: Xiaotian
authors: X
authors: Qi
authors: Chao
authors: C
authors: Liu
authors: Yu
authors: Y
authors: Lan
authors: Aiwen
authors: A
authors: Lei