title: Animal models for the analysis of immune responses to leishmaniasis.
abstract: This unit focuses on the murine model of cutaneous leishmaniasis and models of visceral leishmaniasis in mice and hamsters. Each basic protocol describes the methods used to inoculate parasites and to evaluate infections with regard to lesion progression and visceralization, and quantification of parasite load.
authors: National Institute of Allergy & Infectious Diseases, Bethesda, Maryland.
authors: David L
authors: DL
authors: Sacks
authors: University of Texas Medical Branch (UTMB), Galveston, Texas.
authors: Peter C
authors: PC
authors: Melby
mesh_terms: D000818:Animals; D006224:Cricetinae; D015925:Cryopreservation / Q000379:methods; D004195:Disease Models, Animal; D007891:Leishmania / Q000145:classification / Q000235:genetics / Q000254:growth & development / Q000276:immunology* / Q000302:isolation & purification; D007896:Leishmaniasis / Q000276:immunology* / Q000469:parasitology* / Q000473:pathology; D016773:Leishmaniasis, Cutaneous / Q000276:immunology / Q000469:parasitology; D007898:Leishmaniasis, Visceral / Q000276:immunology / Q000469:parasitology / Q000473:pathology; D008018:Life Cycle Stages; D051379:Mice; D059208:Parasite Load
keywords: animal models; leishmaniasis; liver; sand fly; skin; spleen