title: Preserved emotional memory modulation in first episode psychosis.
abstract: Although patients with schizophrenia have severe memory impairments and emotional deficits, studies investigating emotional memory modulation (EMM) in schizophrenia show contradictory results, possibly due to methodological differences and small group size. We investigated whether impaired EMM is already present in First Episode Psychosis (FEP) and whether impairments in EMM are task or stimulus dependent. Forty-five FEP and thirty-seven Healthy Control (HC) male participants matched for age performed visual and verbal short-term (immediate recall) and long-term (after 24h recognition) memory tasks with neutral, negative and positive stimuli. On all tasks overall memory performance for FEP was significantly below that of HC. Although EMM varied by task and type of stimulus, none of the tasks showed a difference in EMM between FEP and HC. There were no differences between FEP and HC in the way emotion modulates different memory domains. This could mean that EMM is spared in the early course of schizophrenia.
authors: Erasmus University Medical Center, Department of Psychiatry, P.O. box 2040, 3000 CA Rotterdam, The Netherlands; Bavo-Europoort Psychiatric Institute, Oudedijk 76, 3062 AG Rotterdam, The Netherlands. Electronic address: s.dieleman@erasmusmc.nl.
authors: Sieds
authors: S
authors: Dieleman
authors: Erasmus University, Institute of Psychology, Woudestein, T13-01, P.O. box 1738, 3000 DR Rotterdam, The Netherlands. Electronic address: veen@fsw.eur.nl.
authors: Frederik
authors: F
authors: van der Veen
authors: Erasmus University Medical Center, Department of Psychiatry, P.O. box 2040, 3000 CA Rotterdam, The Netherlands; Delta Center for Mental Health Care, Postbus 800, 3170 DZ Poortugaal, The Netherlands. Electronic address: nico.van.beveren@deltapsy.nl.
authors: Nico
authors: N
authors: van Beveren
authors: Erasmus University Medical Center, Department of Psychiatry, P.O. box 2040, 3000 CA Rotterdam, The Netherlands. Electronic address: c.roder@erasmusmc.nl.
authors: Christian
authors: C
authors: Röder
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D016022:Case-Control Studies; D003072:Cognition Disorders / Q000150:complications; D004644:Emotions; D006801:Humans; D008297:Male; D008568:Memory; D008569:Memory Disorders / Q000150:complications*; D008570:Memory, Short-Term; D009426:Netherlands; D009483:Neuropsychological Tests / Q000706:statistics & numerical data; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011618:Psychotic Disorders / Q000523:psychology*; D012559:Schizophrenia / Q000150:complications*; D012565:Schizophrenic Psychology; D014706:Verbal Learning / Q000502:physiology; D055815:Young Adult
keywords: First episode psychosis; Long-term memory; Schizophrenia; Short-term memory; Verbal memory; Visual memory