title: Anticoagulation in the treatment of portovenous emboli after cyanoacrylate injection for a bleeding gastric varix.
abstract: We herein report the use of endoscopic n-butyl-2-cyanoacrylate injections to obliterate a gastric varix, which led to cyanoacrylate embolisation in the splenic and portal veins in a single patient. Cyanoacrylate embolisation is a known but uncommonly reported complication of endoscopic sclerotherapy. This case report illustrates the successful management of this complication (i.e. cyanoacrylate embolisation in the splenic and portal veins) with anticoagulation and analyses the presentation and management of other cases of cyanoacrylate embolisation reported in the literature.
authors: Department of Anaesthesiology, Academia Level 5, Singapore General Hospital, Outram Road, Singapore 169608. Charlene.kwa@mohh.com.sg.
authors: Charlene Xian Wen
authors: CX
authors: Kwa
authors: Veronique Kiak Mien
authors: VK
authors: Tan
authors: Hock Soo
authors: HS
authors: Ong
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000737:chemistry* / Q000627:therapeutic use; D001794:Blood Pressure; D003487:Cyanoacrylates / Q000737:chemistry; D004617:Embolism / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000628:therapy; D004932:Esophageal and Gastric Varices / Q000188:drug therapy*; D006801:Humans; D007267:Injections; D008297:Male; D011169:Portal Vein / Q000473:pathology; D015911:Sclerotherapy; D013162:Splenic Vein / Q000473:pathology; D014057:Tomography, X-Ray Computed; D018608:Ultrasonography, Doppler
chemical_list: D000925:Anticoagulants; D003487:Cyanoacrylates
references: Clin Gastroenterol Hepatol. 2008 Dec;6(12):1412-7
references: 19081529
references: Gastrointest Endosc. 2009 Apr;69(4):967-9
references: 19327488
references: Gastrointest Endosc. 2009 May;69(6):1176-8
references: 19152907
references: Hepatology. 2009 May;49(5):1729-64
references: 19399912
references: Clin Gastroenterol Hepatol. 2010 Sep;8(9):760-6
references: 20621678
references: Radiology. 2000 Jul;216(1):86-92
references: 10887231
references: Hepatology. 2000 Sep;32(3):466-70
references: 10960436
references: Am J Gastroenterol. 2003 Sep;98(9):1982-8
references: 14499775
references: Dig Dis Sci. 1991 Aug;36(8):1164-7
references: 1864211
references: Hepatology. 1992 Dec;16(6):1343-9
references: 1446890
references: Endoscopy. 1996 Jun;28(5):461
references: 8858240
references: J Gastroenterol Hepatol. 1999 Mar;14(3):245-50
references: 10197494
references: J Vasc Interv Radiol. 2005 May;16(5):651-61
references: 15872320
references: Gastrointest Endosc. 2007 Feb;65(2):345-7
references: 17141231
references: Endoscopy. 2007 Feb;39 Suppl 1:E110
references: 17440872