title: Attention drives synchronization of alpha and beta rhythms between right inferior frontal and primary sensory neocortex.
abstract: The right inferior frontal cortex (rIFC) is specifically associated with attentional control via the inhibition of behaviorally irrelevant stimuli and motor responses. Similarly, recent evidence has shown that alpha (7-14 Hz) and beta (15-29 Hz) oscillations in primary sensory neocortical areas are enhanced in the representation of non-attended stimuli, leading to the hypothesis that allocation of these rhythms plays an active role in optimal inattention. Here, we tested the hypothesis that selective synchronization between rIFC and primary sensory neocortex occurs in these frequency bands during inattention. We used magnetoencephalography to investigate phase synchrony between primary somatosensory (SI) and rIFC regions during a cued-attention tactile detection task that required suppression of response to uncertain distractor stimuli. Attentional modulation of synchrony between SI and rIFC was found in both the alpha and beta frequency bands. This synchrony manifested as an increase in the alpha-band early after cue between non-attended SI representations and rIFC, and as a subsequent increase in beta-band synchrony closer to stimulus processing. Differences in phase synchrony were not found in several proximal control regions. These results are the first to reveal distinct interactions between primary sensory cortex and rIFC in humans and suggest that synchrony between rIFC and primary sensory representations plays a role in the inhibition of irrelevant sensory stimuli and motor responses.
authors: Neurosciences Program, Stanford University School of Medicine, Stanford, California, 94305, Department of Psychology, Stanford University, Stanford, California, 94305.
authors: Matthew D
authors: MD
authors: Sacchet
authors: Athinoula A. Martinos Center For Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, 02129.
authors: Roan A
authors: RA
authors: LaPlante
authors: School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, 02138.
authors: Qian
authors: Q
authors: Wan
authors: McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139.
authors: Dominique L
authors: DL
authors: Pritchett
authors: Institute for Learning and Brain Sciences, University of Washington, Seattle, Washington, 98195, Department of Speech and Hearing Sciences, University of Washington, Seattle, Washington, 98195.
authors: Adrian K C
authors: AK
authors: Lee
authors: Athinoula A. Martinos Center For Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, 02129.
authors: Matti
authors: M
authors: Hämäläinen
authors: Department of Neuroscience and Brown Institute for Brain Sciences, Brown University, Providence, Rhode Island, 02912, and.
authors: Christopher I
authors: CI
authors: Moore
authors: Department of Family Medicine, Brown Alpert Medical School, Providence, Rhode Island, 02912.
authors: Catherine E
authors: CE
authors: Kerr
authors: Athinoula A. Martinos Center For Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, 02129, Department of Neuroscience and Brown Institute for Brain Sciences, Brown University, Providence, Rhode Island, 02912, and Stephanie_Jones@brown.edu.
authors: Stephanie R
authors: SR
authors: Jones
mesh_terms: D000328:Adult; D000513:Alpha Rhythm; D001288:Attention; D001611:Beta Rhythm; D003344:Cortical Synchronization; D003463:Cues; D005260:Female; D005625:Frontal Lobe / Q000502:physiology*; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D019579:Neocortex / Q000502:physiology*; D066191:Sensorimotor Cortex / Q000502:physiology*; D055698:Touch Perception
keywords: attention; inferior frontal cortex; magnetoencephalography; primary somatosensory cortex; somatosensation; synchrony
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