title: Diagnosis of early gastric cancer using narrow band imaging and acetic acid.
abstract: OBJECTIVE
  To determine whether the endoscopic findings of depressed-type early gastric cancers (EGCs) could precisely predict the histological type.
  
  
  METHODS
  Ninety depressed-type EGCs in 72 patients were macroscopically and histologically identified. We evaluated the microvascular (MV) and mucosal surface (MS) patterns of depressed-type EGCs using magnifying endoscopy (ME) with narrow-band imaging (NBI) (NBI-ME) and ME enhanced by 1.5% acetic acid, respectively. First, depressed-type EGCs were classified according to MV pattern by NBI-ME. Subsequently, EGCs unclassified by MV pattern were classified according to MS pattern by enhanced ME (EME) images obtained from the same angle.
  
  
  RESULTS
  We classified the depressed-type EGCs into the following 2 MV patterns using NBI-ME: a fine-network pattern that indicated differentiated adenocarcinoma (25/25, 100%) and a corkscrew pattern that likely indicated undifferentiated adenocarcinoma (18/23, 78.3%). However, 42 of the 90 (46.7%) lesions could not be classified into MV patterns by NBI-ME. These unclassified lesions were then evaluated for MS patterns using EME, which classified 33 (81.0%) lesions as MS patterns, diagnosed as differentiated adenocarcinoma. As a result, 76 of the 90 (84.4%) lesions were matched with histological diagnoses using a combination of NBI-ME and EME.
  
  
  CONCLUSIONS
  A combination of NBI-ME and EME was useful in predicting the histological type of depressed-type EGC.
authors: Ken Matsuo, Hidetoshi Takedatsu, Michita Mukasa, Hiroaki Sumie, Hikaru Yoshida, Yasutomo Watanabe, Keita Nakahara, Osamu Tsuruta, Takuji Torimura, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.
authors: Ken
authors: K
authors: Matsuo
authors: Ken Matsuo, Hidetoshi Takedatsu, Michita Mukasa, Hiroaki Sumie, Hikaru Yoshida, Yasutomo Watanabe, Keita Nakahara, Osamu Tsuruta, Takuji Torimura, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.
authors: Hidetoshi
authors: H
authors: Takedatsu
authors: Ken Matsuo, Hidetoshi Takedatsu, Michita Mukasa, Hiroaki Sumie, Hikaru Yoshida, Yasutomo Watanabe, Keita Nakahara, Osamu Tsuruta, Takuji Torimura, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.
authors: Michita
authors: M
authors: Mukasa
authors: Ken Matsuo, Hidetoshi Takedatsu, Michita Mukasa, Hiroaki Sumie, Hikaru Yoshida, Yasutomo Watanabe, Keita Nakahara, Osamu Tsuruta, Takuji Torimura, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.
authors: Hiroaki
authors: H
authors: Sumie
authors: Ken Matsuo, Hidetoshi Takedatsu, Michita Mukasa, Hiroaki Sumie, Hikaru Yoshida, Yasutomo Watanabe, Keita Nakahara, Osamu Tsuruta, Takuji Torimura, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.
authors: Hikaru
authors: H
authors: Yoshida
authors: Ken Matsuo, Hidetoshi Takedatsu, Michita Mukasa, Hiroaki Sumie, Hikaru Yoshida, Yasutomo Watanabe, Keita Nakahara, Osamu Tsuruta, Takuji Torimura, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.
authors: Yasutomo
authors: Y
authors: Watanabe
authors: Ken Matsuo, Hidetoshi Takedatsu, Michita Mukasa, Hiroaki Sumie, Hikaru Yoshida, Yasutomo Watanabe, Keita Nakahara, Osamu Tsuruta, Takuji Torimura, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.
authors: Jun
authors: J
authors: Akiba
authors: Ken Matsuo, Hidetoshi Takedatsu, Michita Mukasa, Hiroaki Sumie, Hikaru Yoshida, Yasutomo Watanabe, Keita Nakahara, Osamu Tsuruta, Takuji Torimura, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.
authors: Keita
authors: K
authors: Nakahara
authors: Ken Matsuo, Hidetoshi Takedatsu, Michita Mukasa, Hiroaki Sumie, Hikaru Yoshida, Yasutomo Watanabe, Keita Nakahara, Osamu Tsuruta, Takuji Torimura, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.
authors: Osamu
authors: O
authors: Tsuruta
authors: Ken Matsuo, Hidetoshi Takedatsu, Michita Mukasa, Hiroaki Sumie, Hikaru Yoshida, Yasutomo Watanabe, Keita Nakahara, Osamu Tsuruta, Takuji Torimura, Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830-0011, Japan.
authors: Takuji
authors: T
authors: Torimura
mesh_terms: D019342:Acetic Acid; D000230:Adenocarcinoma / Q000145:classification / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002454:Cell Differentiation; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D005773:Gastroscopy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D062048:Narrow Band Imaging / Q000379:methods*; D011237:Predictive Value of Tests; D013274:Stomach Neoplasms / Q000145:classification / Q000473:pathology*
chemical_list: D019342:Acetic Acid
keywords: Acetic acid; Diagnosis; Early gastric cancer; Magnifying endoscopy; Narrow band imaging
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