title: Kidney transplantation with organs from donors after circulatory death type 3: a prospective multicentric Spanish study (GEODAS 3).
abstract: To increase the number of kidney donors, new strategies are needed such as living donor programs, expanded criteria donors, or donors after circulatory death (DCD) kidney transplantation programs. The GEODAS group has started an observational, prospective, multicenter clinical study, collecting data from all DCD type-3 kidney transplantations performed in seven Spanish hospitals from January 2012 to January 2014. The preliminary results have shown a delayed graft function of 40.4% and graft survival of 93.7% with a nadir creatinine of 1.3 mg/dL. From all 33 potential donors included in the study, 32 were effective and 63 kidney grafts were transplanted with a utilization rate of 98.5%. Creatinine evolution (median [range]) was in the first month: 2.1 [0.6-5.6]; third month: 1.6 [0.8, 4.2]; first year: 1.6 [0.9-2.2]. These results are similar to kidney transplantation from donors after brain death as shown in the literature, especially in the graft and recipient survival rates. In addition, the controlled programs are easier and less expensive than uncontrolled DCD programs with a higher rate of graft use.
authors: Nephrology Department, Hospital Universitario Puerta de Hierro, Majadahonda, Spain. Electronic address: josem.portoles@salud.madrid.org.
authors: J
authors: J
authors: Portolés Pérez
authors: Nephrology Department, Hospital Universitario Puerta de Hierro, Majadahonda, Spain.
authors: O
authors: O
authors: Lafuente
authors: Nephrology Department, Hospital Universitario Puerta de Hierro, Majadahonda, Spain.
authors: B
authors: B
authors: Sánchez-Sobrino
authors: Nephrology Department, Hospital del Mar, Parc de salut Mar, Barcelona, Spain.
authors: M J
authors: MJ
authors: Pérez Sáez
authors: Nephrology Department, Hospital Universitario de A Coruña, A Coruña, Spain.
authors: A
authors: A
authors: Fernández García
authors: Nephrology Department, Complejo H. Universitario de Albacete, Albacete, Spain.
authors: F
authors: F
authors: Llamas
authors: Nephrology Department, Hospital Universitario Puerta de Hierro, Majadahonda, Spain.
authors: P
authors: P
authors: López-Sánchez
authors: Nephrology Department, Hospital Universitario Gregorio Marañón, Madrid, Spain.
authors: M L
authors: ML
authors: Rodriguez-Ferrero
authors: Nephrology Department, Hospital Universitario Cruces, Bilbao, Spain.
authors: S
authors: S
authors: Zarraga
authors: Nephrology Department, Fundación Jimenez Díaz, Madrid, Spain.
authors: A
authors: A
authors: Ramos
authors: Nephrology Department, Hospital del Mar, Parc de salut Mar, Barcelona, Spain.
authors: J
authors: J
authors: Pascual
mesh_terms: D000328:Adult; D000368:Aged; D003404:Creatinine; D003643:Death; D051799:Delayed Graft Function / Q000453:epidemiology; D046148:Donor Selection; D005260:Female; D006085:Graft Survival; D006801:Humans; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012769:Shock; D013030:Spain; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D003404:Creatinine