title: Investigating the impact of clinical anaesthetic practice on bacterial contamination of intravenous fluids and drugs.
abstract: Syringes (N = 426), ventilator machine swabs (N = 202) and intravenous (IV) fluid administration sets (N = 47) from 101 surgical cases were evaluated for bacterial contamination. Cultures from the external surface of syringe tips and syringe contents were positive in 46% and 15% of cases, respectively. The same bacterial species was cultured from both ventilator and syringe in 13% of cases, and was also detected in the IV fluid administration set in two cases. A significant association was found between emergency cases and contaminated syringes (odds ratio 4.5, 95% confidence interval 1.37-14.8; P = 0.01). Other risk factors included not using gloves and failure to cap syringes.
authors: Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Nottingham, UK. Electronic address: nikunj.mahida@nuh.nhs.uk.
authors: N
authors: N
authors: Mahida
authors: Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors: K
authors: K
authors: Levi
authors: Antimicrobial Resistance and Healthcare Associated Infection Reference Unit, Public Health England, London, UK.
authors: A
authors: A
authors: Kearns
authors: Department of Clinical Microbiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors: S
authors: S
authors: Snape
authors: Anaesthesia and Critical Care, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK.
authors: I
authors: I
authors: Moppett
mesh_terms: D018686:Anesthetics, Intravenous / Q000592:standards*; D003428:Cross Infection / Q000382:microbiology / Q000517:prevention & control; D004340:Drug Contamination / Q000517:prevention & control / Q000706:statistics & numerical data*; D004866:Equipment Contamination / Q000517:prevention & control / Q000706:statistics & numerical data*; D063373:Hand Hygiene / Q000592:standards; D006801:Humans; D019999:Pharmaceutical Solutions / Q000032:analysis; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013594:Syringes / Q000382:microbiology* / Q000592:standards
chemical_list: D018686:Anesthetics, Intravenous; D019999:Pharmaceutical Solutions
keywords: Anaesthesia; Intravenous fluids; Surgery; Syringe