title: Non-recurrence of carbamazepine induced vitiligo after rechallenge with carbamazepine.
abstract: OBJECTIVE
  Vitiligo is a rare side effect of carbamazepine whose exact mechanism is unknown. The aim of this report is to describe a single case of vitiligo induced by carbamazepine.
  
  
  METHODS
  The case was a patient with Bipolar I disorder whose medications were changed from valproate to carbamazepine and who developed vitiligo after a short while. We followed the case for about four years when he was rechallenged with carbamazepine.
  
  
  RESULTS
  When depigmentation occurred, we immediately discontinued carbamazepine after which the depigmented areas improved gradually. About three years later, he received carbamazepine again, but depigmentation did not recur.
  
  
  CONCLUSIONS
  Carbamazepine-induced vitiligo is not an absolute contraindication for the prescription of carbamazepine if other choices fail to respond or are not tolerated. The case has implications for the mechanism of medication induced vitiligo.
authors: Mental Health Research Center and Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
authors: Masoomeh
authors: M
authors: Saeedloo
authors: Mental Health Research Center and Department of Psychiatry, Tehran Institute of Psychiatry-Faculty of Behavioral Sciences and Mental Health, Iran University of Medical Sciences, Tehran, Iran.
authors: Seyed Vahid
authors: SV
authors: Shariat
keywords: bipolar disorder; carbamazepine; vitiligo
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