title: Formal anti-carbopalladation reactions of non-activated alkynes: requirements, mechanistic insights, and applications.
abstract: Formal anti-carbopalladation reactions of CC triple bonds are uncommon, but highly useful transformations. Alkynes can be designed to give anti-carbopalladation products. Prerequisite is the exclusion of other reaction pathways to provoke the cis-trans isomerization of the syn-carbopalladation intermediate. Detailed mechanistic studies of this crucial step by experimental and computational means were performed. Application of an intramolecular version for the synthesis of oligocyclic compounds and substituted dibenzofurans is also described.
authors: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen (Germany).
authors: Martin
authors: M
authors: Pawliczek
authors: Tobias F
authors: TF
authors: Schneider
authors: Christian
authors: C
authors: Maass
authors: Dietmar
authors: D
authors: Stalke
authors: Daniel B
authors: DB
authors: Werz
keywords: anti-carbopalladation; domino reaction; palladium; reaction mechanisms