title: Palladium-catalyzed [4 + 2] cycloaddition of aldimines and 1,4-dipolar equivalents via amphiphilic allylation.
abstract: The combination of Pd catalyst and diethylzinc with triethylborane promotes the amphiphilic allylation of aldimines with 2,3-bismethylenebutane-1,4-diol derivatives to serve as bis-allylic zwitterion species to form 3,4-bismethylenepiperidines via a formal [4 + 2] cycloaddition reaction. 3,4-Bismethylenepiperidine rings are applicable for the synthesis of isoquinoline derivatives via the Diels-Alder reaction followed by an oxidation reaction with DDQ.
authors: Graduate School of Engineering, Nagasaki University , Bunkyo-machi 1-14, Nagasaki 852-8521, Japan.
authors: Goki
authors: G
authors: Hirata
authors: Naoshi
authors: N
authors: Yamada
authors: Shohei
authors: S
authors: Sanada
authors: Gen
authors: G
authors: Onodera
authors: Masanari
authors: M
authors: Kimura