title: New analysis methods for skin fine-structure via optical image and development of 3D skin Cycloscan(™).
abstract: OBJECTIVE
  This study was conducted to develop methods for measuring skin fine-structure via optical image and apparatus for photographing to analyze efficacy of anti-aging.
  
  
  METHODS
  We developed an apparatus named 3D Skin CycloScan(™) to evaluate the efficacy of cosmetics by imagification of skin fine-structure such as wrinkles, pores, and skin texture. The semi-sphere shaped device has 12 different sequential flashing light sources captures optical image simultaneously in one second to exclude the influence of the subject's movement. The normal map that is extracted through shape from shading method is composed of face contour and skin fine-structure parts. When the low-frequency component which is the result of the Gaussian Filter application is eliminated, we can get only skin fine-structure. In this normal map, it is possible to extract two-dimensional vector map called direction map and we can regulate the intensity of the image of wrinkles, pores, and skin texture after filtering the direction map. We performed a clinical study to apply this new apparatus and methods to evaluate an anti-aging efficacy of cosmetics visually and validate with other conventional methods.
  
  
  RESULTS
  After using anti-aging cream including 2% adenosine for 8 weeks, the total amount of fine wrinkle around eye area detected via 3D Skin CycloScan(™) was reduced by 12.1%. Also, wrinkles on crow's feet measured by PRIMOS COMPACT(®) (GFMesstechnik GmbH, Germany) reduced 11.7%.
  
  
  CONCLUSIONS
  According to an aspect of the present study, by changing the direction of the lights toward to subject's skin, we can obtain the information about the fine structures present on the skin such as wrinkles, pores, or skin texture and represent it as an image.
authors: Applied Skin Research Institute, AMOREPACIFIC Corporation, R&D Center, Yongin-si, Giheung-gu, Gyeonggi-do, Korea.
authors: J Y
authors: JY
authors: Han
authors: Department of Cosmetic Science & Technology, Seowon University, Seowon-gu Cheongju, Chungbuk, Korea.
authors: G W
authors: GW
authors: Nam
authors: Applied Skin Research Institute, AMOREPACIFIC Corporation, R&D Center, Yongin-si, Giheung-gu, Gyeonggi-do, Korea.
authors: H K
authors: HK
authors: Lee
authors: Division of Digital Media, Ewha Woman's University, Seoul, Korea.
authors: M J
authors: MJ
authors: Kim
authors: Applied Skin Research Institute, AMOREPACIFIC Corporation, R&D Center, Yongin-si, Giheung-gu, Gyeonggi-do, Korea.|Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
authors: E J
authors: EJ
authors: Kim
mesh_terms: D000328:Adult; D046169:Dermoscopy / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000295:instrumentation* / Q000379:methods; D008029:Lighting / Q000295:instrumentation* / Q000379:methods; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D015595:Skin Aging / Q000187:drug effects / Q000473:pathology*; D063465:Skin Cream / Q000008:administration & dosage*; D016896:Treatment Outcome
keywords: 3D Skin CycloScan™; optical image; pore; skin fine-structure; skin texture; wrinkle