title: The emergence of nanopores in next-generation sequencing.
abstract: Next-generation sequencing methods based on nanopore technology have recently gained considerable attention, mainly because they promise affordable and fast genome sequencing by providing long read lengths (5 kbp) and do not require additional DNA amplification or enzymatic incorporation of modified nucleotides. This permits health care providers and research facilities to decode a genome within hours for less than $1000. This review summarizes past, present, and future DNA sequencing techniques, which are realized by nanopore approaches such as those pursued by Oxford Nanopore Technologies.
authors: STI IBI LBEN, Station 17, Lausanne, Switzerland.
authors: L J
authors: LJ
authors: Steinbock
authors: A
authors: A
authors: Radenovic
mesh_terms: D001483:Base Sequence; D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D015894:Genome, Human; D006801:Humans; D058608:Nanopores; D036103:Nanotechnology / Q000191:economics / Q000379:methods*; D015203:Reproducibility of Results; D017422:Sequence Analysis, DNA / Q000191:economics / Q000379:methods*
chemical_list: D004247:DNA