title: Anticoccidial effects of the root bark of Dictamnus dasycarpus Turcz extract on experimental Eimeria tenella infection.
abstract: Anticoccidial effects of the root bark of Dictamnus dasycarpus Turcz (Rutaceae) extract (DDE) were evaluated in chickens following oral infection with Eimeria (E.) tenella. Three-day-old chickens (n=30) were assigned to three groups (control, untreated, and DDE 0.1% treated). Chickens were fed a standard diet supplemented with or without DDE for 1 week prior to infection with E. tenella (10,000 sporulated oocysts per chicken). The effects of DDE on E. tenella infection were assessed by two parameters; fecal oocysts shedding and body weights gain. The DDE-fed chickens produced significantly reduced fecal oocysts (P<0.05) when compared to the E. tenella-infected group fed standard diet. Also, DDE-based diet, improved body weight loss caused by E. tenella infection. Our data demonstrated that DDE had remarkable anticoccidial activities against E. tenella. This finding might have implications for the development of anticoccidial drug. This study is the first to demonstrate anticoccidial effect of DDE on Eimeria parasites.
authors: Center for Animal Resources Development, Wonkwang University, Iksan, Korea.
authors: Sunhwa
authors: S
authors: Hong
authors: Center for Animal Resources Development, Wonkwang University, Iksan, Korea.
authors: Hyun-A
authors: HA
authors: Lee
authors: Center for Animal Resources Development, Wonkwang University, Iksan, Korea.
authors: Dong-Woo
authors: DW
authors: Kim
authors: Center for Animal Resources Development, Wonkwang University, Iksan, Korea.
authors: Gi-Wook
authors: GW
authors: Oh
authors: Center for Animal Resources Development, Wonkwang University, Iksan, Korea. ; Institute of Animal Experiment & Efficacy Evaluation, Wonkwang University, Iksan, Korea.
authors: Okjin
authors: O
authors: Kim
keywords: Anticoccidial activity; Dictamnus dasycarpus; Rutaceae; eimeria
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