title: Quantitative assessment of physiological cerebrospinal fluid flow in the cervical spinal canal with 3.0T phase-contrast cine MRI.
abstract: A total of 50 healthy volunteers aged between 18 and 54 years underwent phase-contrast cine MRI to assess cerebrospinal fluid flow characteristics in different regions of the vertebral canal. The results revealed that the cerebrospinal fluid peak flow velocity and peak flow rate in the systolic phase were significantly greater than those in the diastolic phase at the same level in the subarachnoid space of the cervical spinal canal. The ventral peak flow velocity and peak flow rate were significantly greater than the post-lateral peak flow velocity and flow rate, while there were no differences between left and right post-lateral subarachnoid peak velocity and flow rate. Moreover, there were no significant differences in peak flow velocity and peak flow rate between the systolic and diastolic phases, ventral, right post-lateral or left post-lateral peak flow velocity and peak flow rate at the same level in the subarachnoid space of the cervical spinal canal among different age groups (18-24, 25-34, 35-44, ≥ 45 years).
authors: Department of Radiology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors: Hua
authors: H
authors: Shang
authors: Department of Radiology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors: Huaijun
authors: H
authors: Liu
authors: Department of Radiology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors: Leka
authors: L
authors: Yan
authors: Department of Radiology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors: Jianming
authors: J
authors: Lei
authors: Department of Radiology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors: Caixia
authors: C
authors: Cui
authors: Department of Radiology, Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China.
authors: Hui
authors: H
authors: Li
keywords: cerebrospinal fluid; flow velocity; magnetic resonance imaging; neural regeneration; phase-contrast; subarachnoid space; vertebral canal
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