title: Bartonella infection in rodents and their flea ectoparasites: an overview.
abstract: Epidemiological studies worldwide have reported a high prevalence and a great diversity of Bartonella species, both in rodents and their flea parasites. The interaction among Bartonella, wild rodents, and fleas reflects a high degree of adaptation among these organisms. Vertical and horizontal efficient Bartonella transmission pathways within flea communities and from fleas to rodents have been documented in competence studies, suggesting that fleas are key players in the transmission of Bartonella to rodents. Exploration of the ecological traits of rodents and their fleas may shed light on the mechanisms used by bartonellae to become established in these organisms. The present review explores the interrelations within the Bartonella-rodent-flea system. The role of the latter two components is emphasized.
authors: 1 Koret School of Veterinary Medicine, The Hebrew University of Jerusalem , Israel .
authors: Ricardo
authors: R
authors: Gutiérrez
authors: Boris
authors: B
authors: Krasnov
authors: Danny
authors: D
authors: Morick
authors: Yuval
authors: Y
authors: Gottlieb
authors: Irina S
authors: IS
authors: Khokhlova
authors: Shimon
authors: S
authors: Harrus
mesh_terms: D000818:Animals; D001473:Bartonella; D001474:Bartonella Infections / Q000635:transmission / Q000662:veterinary; D004199:Disease Vectors; D055669:Ecological and Environmental Phenomena; D058267:Flea Infestations; D012376:Rodent Diseases / Q000453:epidemiology / Q000382:microbiology*; D012377:Rodentia / Q000382:microbiology* / Q000469:parasitology*; D005423:Siphonaptera / Q000382:microbiology*; D015047:Zoonoses
keywords: Bartonella; Fleas; Rodents
references: PLoS Genet. 2011 Feb 10;7(2):e1001296
references: 21347280
references: Comp Immunol Microbiol Infect Dis. 2010 Mar;33(2):95-107
references: 20097421
references: Epidemiol Infect. 2003 Feb;130(1):149-57
references: 12613756
references: Med Vet Entomol. 2008 Mar;22(1):1-15
references: 18380649
references: Int J Syst Evol Microbiol. 2013 May;63(Pt 5):1734-1740
references: 22941296
references: J Wildl Dis. 1999 Apr;35(2):275-84
references: 10231754
references: Appl Environ Microbiol. 2008 Aug;74(16):5086-92
references: 18606803
references: J Exp Med. 2001 May 7;193(9):1077-86
references: 11342592
references: J Parasitol. 2006 Apr;92(2):313-8
references: 16729688
references: J Clin Microbiol. 2005 Feb;43(2):945-7
references: 15695714
references: Vector Borne Zoonotic Dis. 2008 Aug;8(4):467-74
references: 18399782
references: Vector Borne Zoonotic Dis. 2013 Mar;13(3):164-75
references: 23421888
references: Appl Environ Microbiol. 2010 Dec;76(24):8062-70
references: 20935117
references: Epidemics. 2010 Dec;2(4):165-72
references: 21352787
references: Infect Immun. 1998 Nov;66(11):5534-6
references: 9784568
references: Appl Environ Microbiol. 2007 Jul;73(13):4308-16
references: 17483286
references: Am J Trop Med Hyg. 2009 Nov;81(5):811-6
references: 19861616
references: Clin Microbiol Rev. 2012 Jan;25(1):42-78
references: 22232371
references: Am J Trop Med Hyg. 1999 May;60(5):799-805
references: 10344656
references: Appl Environ Microbiol. 2007 Oct;73(19):6045-52
references: 17693558
references: Comp Immunol Microbiol Infect Dis. 2012 Dec;35(6):583-9
references: 22898354
references: Int J Syst Evol Microbiol. 2004 Nov;54(Pt 6):1959-1967
references: 15545418
references: Parasitology. 2013 Jan;140(1):61-8
references: 22938938
references: Ann N Y Acad Sci. 2005 Dec;1063:270-9
references: 16481527
references: Zoonoses Public Health. 2010 Sep;57(6):439-46
references: 19538457
references: Appl Environ Microbiol. 2013 Jun;79(11):3438-43
references: 23542614
references: Future Microbiol. 2013 Sep;8(9):1117-28
references: 24020740
references: Ann Trop Med Parasitol. 2000 Jan;94(1):55-68
references: 10723524
references: J Vector Ecol. 2008 Dec;33(2):353-64
references: 19263856
references: Nat Genet. 2007 Dec;39(12):1469-76
references: 18037886
references: PLoS Negl Trop Dis. 2013 May 30;7(5):e2246
references: 23738028
references: ISME J. 2013 Jan;7(1):221-3
references: 22739493
references: APMIS. 2004 Jun;112(6):336-41
references: 15511270
references: N Engl J Med. 2007 Jun 7;356(23):2381-7
references: 17554119
references: Am J Trop Med Hyg. 2009 Jul;81(1):55-8
references: 19556567
references: Appl Environ Microbiol. 2013 Feb;79(4):1258-64
references: 23241972
references: PLoS One. 2013 Jul 24;8(7):e68956
references: 23894381
references: Emerg Infect Dis. 2012 Apr;18(4):631-3
references: 22469313
references: J Parasitol. 2004 Jun;90(3):485-9
references: 15270090
references: Vector Borne Zoonotic Dis. 2005 Winter;5(4):402-9
references: 16417436
references: Vector Borne Zoonotic Dis. 2013 Jul;13(7):457-67
references: 23590324
references: Mol Ecol. 2013 Sep;22(18):4747-52
references: 23875817
references: Appl Environ Microbiol. 2010 Dec;76(24):8247-54
references: 21037303
references: Comp Immunol Microbiol Infect Dis. 2000 Oct;23(4):221-38
references: 11038125
references: Vet Microbiol. 2009 Oct 20;139(1-2):197-201
references: 19574002
references: Am J Trop Med Hyg. 1997 Nov;57(5):578-88
references: 9392599
references: Int J Syst Bacteriol. 1996 Oct;46(4):891-7
references: 8863415
references: J Med Entomol. 2001 Sep;38(5):629-37
references: 11580034
references: J Med Entomol. 2003 May;40(3):329-37
references: 12943112
references: J Clin Microbiol. 2013 Aug;51(8):2781-4
references: 23740723
references: J Clin Microbiol. 1995 Dec;33(12):3245-51
references: 8586710
references: Mol Ecol. 2010 Jun;19(11):2241-55
references: 20465583
references: Vet Microbiol. 2002 Oct 22;89(2-3):211-21
references: 12243898
references: Infect Genet Evol. 2012 Jul;12(5):894-904
references: 22449771
references: Int J Syst Evol Microbiol. 2010 Apr;60(Pt 4):759-763
references: 19656930
references: Vet Microbiol. 2012 May 25;157(1-2):132-6
references: 22204791
references: Zhonghua Liu Xing Bing Xue Za Zhi. 2009 Oct;30(10):989-92
references: 20193373
references: ISME J. 2014 Aug;8(8):1598-608
references: 24577352
references: J Clin Microbiol. 2004 Aug;42(8):3816-8
references: 15297537
references: Ecology. 2007 Jul;88(7):1841-9
references: 17645030
references: Onderstepoort J Vet Res. 2012 Jun 20;79(2):452
references: 23327372
references: Trends Ecol Evol. 2010 Jan;25(1):21-7
references: 19782425
references: Comp Immunol Microbiol Infect Dis. 2011 Dec;34(6):465-73
references: 21908045
references: Clin Infect Dis. 2001 Mar 15;32(6):897-928
references: 11247714
references: J Vet Med Sci. 2011 Dec;73(12):1561-7
references: 21791887
references: J Med Entomol. 2002 Nov;39(6):915-9
references: 12495192
references: J Med Entomol. 1998 Sep;35(5):625-8
references: 9775583
references: Am J Trop Med Hyg. 2013 Sep;89(3):462-5
references: 23836577
references: ISME J. 2010 Jul;4(7):955-8
references: 20220787
references: Am J Pathol. 2008 Apr;172(4):1005-18
references: 18292236
references: Int J Syst Bacteriol. 1993 Oct;43(4):777-86
references: 8240958
references: Parasitology. 1997 Feb;114 ( Pt 2):159-73
references: 9051922
references: Emerg Infect Dis. 2004 Apr;10(4):684-7
references: 15200860
references: FEMS Immunol Med Microbiol. 2007 Jun;50(1):45-50
references: 17374132
references: Parasitology. 2010 Nov;137(13):1925-35
references: 20619065
references: Appl Environ Microbiol. 2011 Nov;77(21):7850-2
references: 21908631
references: Appl Environ Microbiol. 2012 Dec;78(23):8463-6
references: 22983968
references: Am J Trop Med Hyg. 2010 Oct;83(4):917-23
references: 20889892
references: Am J Trop Med Hyg. 2004 Apr;70(4):429-33
references: 15100459
references: Am J Trop Med Hyg. 2007 Sep;77(3):567-70
references: 17827381
references: Vector Borne Zoonotic Dis. 2014 Jan;14(1):33-40
references: 24359425
references: PLoS Negl Trop Dis. 2011;5(5):e1186
references: 21655306
references: Vector Borne Zoonotic Dis. 2008 Oct;8(5):695-700
references: 18620508
references: Am J Trop Med Hyg. 2006 Mar;74(3):436-9
references: 16525103
references: J Wildl Dis. 1998 Apr;34(2):305-9
references: 9577777
references: Vector Borne Zoonotic Dis. 2004 Winter;4(4):285-95
references: 15671735
references: Am Nat. 2004 Oct;164(4):506-16
references: 15459881
references: J Clin Microbiol. 1999 Aug;37(8):2598-601
references: 10405408
references: Parasitology. 2010 Jun;137(7):1069-77
references: 20388232
references: Appl Environ Microbiol. 2010 Oct;76(20):6864-9
references: 20802081
references: J Exp Med. 1946 Jul;84:37-50
references: 20988749
references: Appl Environ Microbiol. 2013 Aug;79(16):5082-4
references: 23747696
references: PLoS Genet. 2013 Mar;9(3):e1003393
references: 23555299
references: Clin Microbiol Infect. 2009 Dec;15 Suppl 2:102-3
references: 19929978
references: PLoS Genet. 2009 Jul;5(7):e1000546
references: 19578403
references: Vet Immunol Immunopathol. 1999 Nov 30;71(3-4):233-43
references: 10587303
references: Am J Trop Med Hyg. 2012 Aug;87(2):319-26
references: 22855765
references: PLoS Pathog. 2010 Jun 10;6(6):e1000946
references: 20548954
references: J Clin Microbiol. 1993 Apr;31(4):872-81
references: 7681847
references: Int J Syst Evol Microbiol. 2000 Nov;50 Pt 6:1973-1979
references: 11155970
references: J Wildl Dis. 2006 Oct;42(4):739-49
references: 17255440
references: J Immunol. 2001 Jul 1;167(1):11-4
references: 11418625
references: J Wildl Dis. 2010 Jan;46(1):179-85
references: 20090031
references: Vet Microbiol. 2009 Nov 18;139(3-4):293-7
references: 19595521
references: Emerg Infect Dis. 2008 Jul;14(7):1074-80
references: 18598628
references: Appl Environ Microbiol. 2004 Oct;70(10):6302-5
references: 15466580
references: Int J Syst Bacteriol. 1995 Jan;45(1):1-8
references: 7857789
references: Comp Immunol Microbiol Infect Dis. 2011 Jul;34(4):299-314
references: 21616536
references: Emerg Infect Dis. 2009 Dec;15(12):2080-6
references: 19998749
references: Int J Syst Evol Microbiol. 2009 Dec;59(Pt 12):2956-61
references: 19628592
references: Vector Borne Zoonotic Dis. 2004 Winter;4(4):296-305
references: 15671736
references: J Vet Sci. 2005 Dec;6(4):327-34
references: 16293997
references: Vector Borne Zoonotic Dis. 2008 Spring;8(1):1-5
references: 18237261
references: Vet Res. 2009 Mar-Apr;40(2):29
references: 19284965
references: Parasitology. 2007 Mar;134(Pt 3):413-25
references: 17096870
references: J Clin Microbiol. 2003 Feb;41(2):645-50
references: 12574261
references: Parasitology. 2012 Jun;139(7):881-93
references: 22336264
references: Appl Environ Microbiol. 2011 Mar;77(5):1728-31
references: 21239553
references: Clin Microbiol Infect. 2009 Dec;15 Suppl 2:95-7
references: 19374642
references: Microb Ecol. 2012 Aug;64(2):525-36
references: 22419104
references: Southeast Asian J Trop Med Public Health. 2005 Nov;36(6):1523-9
references: 16610656
references: Ann N Y Acad Sci. 2005 Dec;1063:308-11
references: 16481532
references: J Infect Dis. 1999 Jul;180(1):220-4
references: 10353885
references: J Biol Dyn. 2012;6:763-81
references: 22873616
references: Emerg Infect Dis. 2004 May;10(5):963-4
references: 15216849
references: Vector Borne Zoonotic Dis. 2006 Winter;6(4):395-403
references: 17187575
references: J Vet Sci. 2008 Sep;9(3):285-93
references: 18716449
references: Int J Syst Bacteriol. 1998 Oct;48 Pt 4:1333-9
references: 9828434
references: Med Vet Entomol. 2002 Sep;16(3):266-76
references: 12243227
references: Mol Ecol. 2011 Jul;20(13):2864-70
references: 21692752
references: J Clin Microbiol. 2009 Jul;47(7):2332-5
references: 19439538
references: Emerg Infect Dis. 2009 Apr;15(4):526-32
references: 19331727
references: Epidemiol Infect. 2002 Dec;129(3):647-53
references: 12558350
references: Infect Immun. 2001 Sep;69(9):5313-7
references: 11500400
references: Vet Res. 2012 Feb 27;43:15
references: 22369683
references: J Clin Microbiol. 1999 Dec;37(12):4034-8
references: 10565926
references: Vector Borne Zoonotic Dis. 2012 May;12(5):366-71
references: 22217173
references: Microb Ecol. 2008 Aug;56(2):373-82
references: 18176820
references: Am J Trop Med Hyg. 2002 May;66(5):622-7
references: 12201602
references: FEMS Microbiol Ecol. 2007 Sep;61(3):438-48
references: 17672850
references: J Vector Ecol. 2001 Dec;26(2):181-90
references: 11813655
references: Z Tropenmed Parasitol. 1962 Apr;13:34-53
references: 14459317
references: Microb Ecol. 2011 Jan;61(1):134-45
references: 20740281
references: Oecologia. 2005 Dec;146(2):209-17
references: 16025350
references: J Med Microbiol. 2008 Dec;57(Pt 12):1496-1501
references: 19018019
references: Neurosci Biobehav Rev. 2000 Aug;24(6):669-86
references: 10940441
references: Comp Immunol Microbiol Infect Dis. 2013 Mar;36(2):105-11
references: 23200028
references: J Clin Microbiol. 2008 Feb;46(2):772-5
references: 18077632
references: Epidemiol Infect. 2001 Apr;126(2):323-9
references: 11349984
references: J Wildl Dis. 2010 Jan;46(1):173-8
references: 20090030
references: Appl Environ Microbiol. 2008 Mar;74(5):1667-70
references: 18203862