title: Surgical results of Ahmed valve implantation combined with intravitreal triamcinolone acetonide injection for preventing choroidal detachment.
abstract: BACKGROUND
  To investigate the surgical results of Ahmed valve implantation with intravitreal triamcinolone acetonide injection (IVTA) in patients with aphakic or pseudophakic glaucoma.
  
  
  METHODS
  Fifty-nine patients who underwent Ahmed valve implantation were consecutively recruited from November 2005 to August 2011 at the Beijing Tongren Hospital. In the IVTA group (29 eyes), 4 mg of TA was injected into the vitreous cavity during Ahmed valve implantation was performed. In the control group (30 eyes), only Ahmed valve implantation was performed. The primary outcome was intraocular pressure (IOP). The visual acuity (VA), supplemental medical therapy and complications were evaluated as secondary outcomes.
  
  
  RESULTS
  The IVTA and control groups were followed up for a mean of 22.7 and 31.4 months, respectively. IOP decreased in both groups at 1 day, 1 week, 1 month and the final follow-up points after the surgery. However, there was no significant difference between 2 groups at all intervals (P > 0.05). The rate of shallow anterior chamber and choroidal detachment in IVTA group was significantly lower than control group (6.9% vs. 40%, P = 0.007; 0% vs. 26.7%, P = 0.009).
  
  
  CONCLUSIONS
  Ahmed valve implantation combined IVTA seems to be effective to reduce the incidence of complications for treatment of aphakic or pseudophakic glaucoma.
authors: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, NO.1 Dongjiaominxiang street, Dongcheng District, Beijing, 100730, China.
authors: Hua
authors: H
authors: Wang
authors: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, NO.1 Dongjiaominxiang street, Dongcheng District, Beijing, 100730, China. chenhongyk@163.com.
authors: Hong
authors: H
authors: Chen
authors: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, NO.1 Dongjiaominxiang street, Dongcheng District, Beijing, 100730, China.
authors: Yue
authors: Y
authors: Qi
authors: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, NO.1 Dongjiaominxiang street, Dongcheng District, Beijing, 100730, China.|Beijing Institute of Ophthalmology, NO.17 Chongneihougou street, Beijing, 100005, China.
authors: Ning-Li
authors: NL
authors: Wang
mesh_terms: D000328:Adult; D000368:Aged; D001035:Aphakia / Q000150:complications; D015862:Choroid Diseases / Q000517:prevention & control*; D003131:Combined Modality Therapy; D005260:Female; D005901:Glaucoma / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D020327:Glaucoma Drainage Implants; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D058449:Intravitreal Injections; D008297:Male; D008875:Middle Aged; D019919:Prosthesis Implantation; D019591:Pseudophakia / Q000150:complications; D012189:Retrospective Studies; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000627:therapeutic use*; D014792:Visual Acuity / Q000502:physiology
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide
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