title: Anticoagulation therapy: Perioperative anticoagulation-are we at 'a bridge too far'?
abstract: The perioperative management of patients with atrial fibrillation who require an elective surgical or other invasive procedure is an area of ongoing uncertainty. Accumulating evidence from observational studies suggests that the use of bridging anticoagulation with heparin, although well-intentioned, might not reduce perioperative thromboembolism and can increase bleeding.
authors: St. Joseph's Healthcare Hamilton, Room F-544, 50 Charlton Avenue East, Hamilton, ON L8N 4A6, Canada.
authors: James D
authors: JD
authors: Douketis
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy*; D006801:Humans; D019990:Perioperative Care / Q000009:adverse effects* / Q000379:methods; D019106:Postoperative Hemorrhage / Q000209:etiology; D020521:Stroke / Q000517:prevention & control; D013923:Thromboembolism / Q000517:prevention & control
chemical_list: D000925:Anticoagulants
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