title: Ruthenium-catalyzed synthesis of 2,3-cyclo[3]dendralenes and complex polycycles from propargyl alcohols.
abstract: Ruthenium-catalyzed cascade transformations for the synthesis of 2,3-cyclo[3]dendralenes and multicomponent processes based thereon to generate complex polycycles are presented. The combination of allylation-cyclization sequences with diene-transmissive Diels-Alder reactions allows the rapid and selective construction of natural-product-like motifs from easily accessible starting materials in a one-pot process and provides a new method to access potential drug candidates.
authors: Institut für Chemie, Otto-von-Guericke-Universität Magdeburg, Universitätsplatz 2, 39106 Magdeburg (Germany) http://www.ich.ovgu.de.
authors: Nora
authors: N
authors: Thies
authors: Edgar
authors: E
authors: Haak
keywords: dendralenes; homogeneous catalysis; molecular complexity; multicomponent reactions; ruthenium