title: TGF-β may control the switch between tumorigenic growth and "stem cell/mesenchymal" potentially drug-resistant states.
authors: Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.
authors: Jenna R
authors: JR
authors: Bordelon
authors: Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.|Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA.|Interdisciplinary Stem Cell Institute, Miller School of Medicine, University of Miami, Miami, FL, USA.
authors: James M
authors: JM
authors: Grichnik
mesh_terms: D000818:Animals; D049109:Cell Proliferation / Q000187:drug effects; D019008:Drug Resistance, Neoplasm; D006801:Humans; D008544:Melanocytes / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D008545:Melanoma / Q000188:drug therapy / Q000378:metabolism* / Q000473:pathology; D059630:Mesenchymal Stem Cells / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D051379:Mice; D014411:Neoplastic Stem Cells / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D015398:Signal Transduction; D012878:Skin Neoplasms / Q000188:drug therapy / Q000378:metabolism* / Q000473:pathology; D016212:Transforming Growth Factor beta / Q000378:metabolism*
chemical_list: D016212:Transforming Growth Factor beta
keywords: TGF-beta; differentiation; drug-resistance; epithelial-mesenchymal transition; melanoma; tumor stem cells