title: Bacteriophage Transduction in Staphylococcus aureus.
abstract: The genetic manipulation of Staphylococcus aureus for molecular experimentation is a valuable tool for assessing gene function and virulence. Genetic variability between strains coupled with difficult laboratory techniques for strain construction is a frequent roadblock in S. aureus research. Bacteriophage transduction greatly increases the speed and ease of S. aureus studies by allowing movement of chromosomal markers and plasmids between strains. This technique enables the S. aureus research community to focus investigations on clinically relevant isolates.
authors: Department of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL, 62702, USA. molson39@siumed.edu.
authors: Michael E
authors: ME
authors: Olson
mesh_terms: D001435:Bacteriophages / Q000235:genetics*; D006801:Humans; D008242:Lysogeny / Q000235:genetics; D010957:Plasmids / Q000235:genetics; D013203:Staphylococcal Infections / Q000235:genetics* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000235:genetics*; D014161:Transduction, Genetic / Q000379:methods*
keywords: Bacteriophage; Bacteriophage 80α; Bacteriophage Φ11; Staphylococcus aureus; Transduction