title: Fever, jaundice and acute renal failure.
abstract: Leptospirosis is an uncommon infectious disease that has protean clinical manifestations ranging from an innocuous 'flu-like' illness to potentially life-threatening multi-organ failure. Here we describe a case of Weil's disease that presented on the acute medical take with fever, jaundice and acute renal failure. We highlight the importance of careful history taking at the time of admission and how understanding the epidemiology and pathophysiology of leptospirosis enables a definitive diagnosis to be reached.
authors: Department of Endocrinology, Newham University Hospital, Barts Health NHS Trust, London, UK samuel.otoole2@bartshealth.nhs.uk.
authors: Sam M
authors: SM
authors: O'Toole
authors: Department of Endocrinology, Newham University Hospital, Barts Health NHS Trust, London, UK.
authors: Neha
authors: N
authors: Pathak
authors: Department of Endocrinology, Newham University Hospital, Barts Health NHS Trust, London, UK.
authors: Graham C
authors: GC
authors: Toms
authors: Department of Endocrinology, Newham University Hospital, Barts Health NHS Trust, London, UK.
authors: Susan V
authors: SV
authors: Gelding
authors: Leptospira Reference Unit, Wye Valley NHS Trust, Hereford, UK.
authors: Venkat
authors: V
authors: Sivaprakasam
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000382:microbiology; D003937:Diagnosis, Differential; D005334:Fever / Q000209:etiology / Q000382:microbiology; D006801:Humans; D007565:Jaundice / Q000209:etiology / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D014895:Weil Disease
keywords: Leptospirosis; Weil’s disease; acute renal failure; fever; jaundice
references: Swiss Med Wkly. 2004 Jun 12;134(23-24):347-52
references: 15318284
references: Cochrane Database Syst Rev. 2012 Feb 15;(2):CD008264
references: 22336839