title: Practical approach to the use of daylight photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: a European consensus.
abstract: BACKGROUND
  Daylight-mediated photodynamic therapy has been shown to be an effective therapy for actinic keratoses (AKs) and a simple and tolerable treatment procedure in three randomized Scandinavian studies and two recent Phase III randomized controlled studies in Australia and Europe.
  
  
  OBJECTIVE
  To establish consensus recommendations for the use of daylight photodynamic therapy (DL-PDT) using topical methyl aminolaevulinate (MAL) in European patients with AKs.
  
  
  METHODS
  The DL-PDT consensus recommendations were developed on behalf of the European Society for Photodynamic Therapy in Dermatology and comprised of 10 dermatologists from different European countries with experience in how to treat AK patients with PDT. Consensus was developed based on literature review and experience of the experts in the treatment of AK using DL-PDT.
  
  
  RESULTS
  The recommendations arising from this panel of experts provide general guidance on the use of DL-PDT as a dermatological procedure with specific guidance regarding patient selection, therapeutic indications, when to treat, pre-treatment skin preparation, MAL application and daylight exposure for patients with AK in different countries of Europe.
  
  
  CONCLUSIONS
  This consensus recommendation provides a framework for physicians to perform DL-PDT with MAL cream while ensuring efficiency and safety in the treatment of patients with AK in different European countries.
authors: Department of Dermatology, Stirling Community Hospital, Stirling, UK.
authors: C A
authors: CA
authors: Morton
authors: Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
authors: H C
authors: HC
authors: Wulf
authors: Department of Dermatology and Allergology, Klinikum Vest GmbH Academic Teaching Hospital, Recklinghausen, Germany.
authors: R M
authors: RM
authors: Szeimies
authors: Department of Dermatology, Hospital San Jorge, Huesca, Spain.
authors: Y
authors: Y
authors: Gilaberte
authors: Département de Dermatologie, Hôpital Saint-Louis, Paris, France.
authors: N
authors: N
authors: Basset-Seguin
authors: First Dermatology Department, Aristotle University, Thessaloniki, Greece.
authors: E
authors: E
authors: Sotiriou
authors: Unit of Dermatology, Department of Medicine, University of Padova, Padova, Italy.
authors: S
authors: S
authors: Piaserico
authors: Department of Dermatology, Inselspital, University of Bern, Bern, Switzerland.
authors: R E
authors: RE
authors: Hunger
authors: Department of Dermatology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis UZ Brussel, Brussels, Belgium.
authors: S
authors: S
authors: Baharlou
authors: Department of Dermatology and Venereology, Medical University, Innsbruck, Innsbruck, Austria.
authors: A
authors: A
authors: Sidoroff
authors: Dermatology, Bern, Im Holenacker 16, CH-3063, Ittigen, Switzerland.
authors: L R
authors: LR
authors: Braathen
mesh_terms: D000287:Administration, Topical; D000622:Aminolevulinic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D005060:Europe; D006801:Humans; D055623:Keratosis, Actinic / Q000188:drug therapy*; D010778:Photochemotherapy / Q000592:standards*; D017319:Photosensitizing Agents / Q000008:administration & dosage; D012955:Societies, Medical
chemical_list: D017319:Photosensitizing Agents; C475457:methyl 5-aminolevulinate; D000622:Aminolevulinic Acid