title: Dengue: an update for clinicians working in non-endemic areas.
abstract: Dengue is one of the most rapidly emerging viral infections globally, with 2.5 billion people now thought to live in dengue-endemic areas. In addition, reports of travel-related and autochthonous infections are increasing in non-endemic areas. Most patients with dengue experience a self-limiting febrile illness, but a proportion develop potentially life threatening complications around the time of fever clearance, including plasma leakage occasionally leading to shock, bleeding, and organ impairment. As dengue can present with non-specific symptoms of fever, headache and myalgias, the potential for misdiagnosis and inappropriate management by medical staff inexperienced with the disease is a concern. This short review will outline the latest World Health Organisation disease classification, potential complications, clinical assessment and management for clinicians working in non-endemic areas.
authors: Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, and specialist registrar in infectious diseases, Imperial College, Department of Medicine, London, UK syacoub@imperial.ac.uk.
authors: Sophie
authors: S
authors: Yacoub
authors: Wellcome Trust Major Overseas Programme, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, and professor of tropical medicine, Nuffield Department of Clinical Medicine, Centre for Tropical Medicine, Oxford, UK.
authors: Bridget
authors: B
authors: Wills
mesh_terms: D003715:Dengue / Q000150:complications / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D005076:Exanthema / Q000473:pathology / Q000821:virology; D006801:Humans; D012867:Skin / Q000473:pathology
keywords: Dengue; clinical; management; travel; update
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