title: Streptococcus bovis endocarditis: analysis of cases between 2005 and 2014.
abstract: BACKGROUND
  Streptococcus bovis is a classical etiology of endocarditis and is associated with colonic lesions. No series of cases from Brazil has been described.
  
  
  OBJECTIVE
  To describe aspects of S. bovis endocarditis.
  
  
  METHODS
  This is a case series of patients admitted to a cardiac surgery referral center, during the years 2005-2014. Clinical, laboratory, echochardiographic, colonoscopic, treatment, surgical and outcome variables were studied.
  
  
  RESULTS
  Nine patients with S. bovis endocarditis were included; all cases fulfilled the modified Duke criteria. Incidence was 8/220 (4%) in years 2006-2014. There were seven male and two female patients; mean age was 56.7 years, standard deviation 13.4. All patients had native aortic valve involvement. Presentation was subacute in 7/9 (71%). Fever was present in 7/9 (77.7%), embolic lesions to solid organs occurred in three, and perivalvular abscess in two patients. All echocardiograms showed moderate to severe valvular regurgitation and vegetations. Microcytic anemia was seen in 7/7 patients. Colonoscopy showed abnormal findings in 7/9 (77.7%). Surgery was indicated for 6/9 patients due to acute aortic regurgitation and left ventricular failure. All patients were discharged home.
  
  
  CONCLUSIONS
  S. bovis most frequently affected the aortic valve of male patients. Colon disease was frequent. Surgery was indicated frequently due to hemodynamic compromise.
authors: Unigranrio, Rio de Janeiro, RJ, Brazil.
authors: Renato
authors: R
authors: Mello
authors: Instituto Nacional de Cardiologia, Rio de Janeiro, RJ, Brazil.
authors: Marisa
authors: M
authors: da Silva Santos
authors: Instituto Nacional de Cardiologia, Rio de Janeiro, RJ, Brazil.
authors: Wilma
authors: W
authors: Golebiosvki
authors: Instituto Nacional de Cardiologia, Rio de Janeiro, RJ, Brazil.
authors: Clara
authors: C
authors: Weksler
authors: Unigranrio, Rio de Janeiro, RJ, Brazil; Instituto Nacional de Cardiologia, Rio de Janeiro, RJ, Brazil; Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, RJ, Brazil. Electronic address: cristianelamas@gmail.com.
authors: Cristiane
authors: C
authors: Lamas
mesh_terms: D000328:Adult; D000368:Aged; D003108:Colonic Diseases / Q000150:complications* / Q000382:microbiology; D003113:Colonoscopy; D004697:Endocarditis, Bacterial / Q000150:complications* / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013290:Streptococcal Infections / Q000150:complications* / Q000382:microbiology; D016985:Streptococcus bovis / Q000302:isolation & purification*
keywords: Cardiac surgery; Colonic lesions; Infective endocarditis; Streptococcus bovis group
references: Am J Cardiol. 2001 Oct 15;88(8):871-5
references: 11676950
references: Infection. 2014 Oct;42(5):835-42
references: 24934541
references: Clin Microbiol Rev. 2002 Oct;15(4):613-30
references: 12364372
references: Clin Infect Dis. 2000 Apr;30(4):633-8
references: 10770721
references: Clin Infect Dis. 2011 Nov;53(9):870-8
references: 21960713
references: Arch Intern Med. 2009 Mar 9;169(5):463-73
references: 19273776
references: Eur Heart J. 1995 Dec;16(12):1975-80
references: 8682035
references: Int J Infect Dis. 2013 Jan;17(1):e65-6
references: 23219032
references: Clin Infect Dis. 1994 Aug;19(2):361-2
references: 7986925
references: Int J Infect Dis. 2010 May;14(5):e394-8
references: 19800277
references: Am J Med. 1994 Mar;96(3):200-9
references: 8154507
references: J Infect. 2010 Oct;61(4):307-13
references: 20659498
references: Clin Infect Dis. 2004 May 15;38(10):1394-400
references: 15156477
references: Colorectal Dis. 2014 Sep;16(9):672-80
references: 24824513
references: Eur J Clin Microbiol Infect Dis. 2008 Apr;27(4):285-91
references: 18183440
references: Clin Microbiol Infect. 2005 Oct;11(10):814-9
references: 16153255
references: Gen Thorac Cardiovasc Surg. 2014 Mar;62(3):142-8
references: 24022385
references: Arch Surg. 2004 Jul;139(7):760-5
references: 15249410
references: Heart. 1998 Sep;80(3):276-80
references: 9875088
references: Arq Bras Cardiol. 1990 Jan;54(1):13-21
references: 2264765