title: The human mitochondrial genome may code for more than 13 proteins.
abstract: The human mitochondrial (mt) DNA is commonly described as a small, maternally inherited molecule that encodes 13 protein components of the oxidative phosphorylation system and 24 structural RNAs required for their translation. However, recent studies indicate that the human mtDNA has a larger functional repertoire than previously believed. This paper briefly summarizes these studies, which suggest to reconsider our way to describe the human mitochondrial DNA as it may code for more than 13 proteins.
authors: a Département de Sciences Biologiques , Université de Montréal , Montréal , Québec , Canada and.
authors: Charlotte
authors: C
authors: Capt
authors: b Dipartimento di Scienze Biologiche , Geologiche ed Ambientali, University of Bologna , Bologna , Italy.
authors: Marco
authors: M
authors: Passamonti
authors: a Département de Sciences Biologiques , Université de Montréal , Montréal , Québec , Canada and.
authors: Sophie
authors: S
authors: Breton
mesh_terms: D000595:Amino Acid Sequence; D002874:Chromosome Mapping; D002877:Chromosomes, Human; D019295:Computational Biology / Q000379:methods; D023061:Gene Order; D050259:Genes, Mitochondrial; D054629:Genome, Mitochondrial; D023281:Genomics / Q000379:methods; D006801:Humans; D016366:Open Reading Frames
keywords: Genomics; humanin; mitochondrial DNA; mtDNA; open reading frames