title: Quantitative sonography of basal cell carcinoma.
abstract: A 30-MHz ultrasonic scanner was used to collect B-scan images together with appropriate radiofrequency echoes from diseased and healthy skin regions of patients with diagnosed basal cell carcinoma and pre-cancerous lesions (actinic keratosis). Radiofrequency data were processed to obtain the attenuation coefficient and statistics of the backscattered echo signal determination (K-distribution and effective density of scatterers [EDS]). The attenuation coefficient was significantly higher for patients with basal cell carcinoma than for healthy patients. Also, the pre-cancerous skin lesions had increased attenuation. The averaged EDS values for cancer lesions were significantly lower than those for pre-cancerous lesions and healthy skin. The successful differentiation between the tissue groups examined suggests the potential value of the attenuation coefficient and EDS for carcinoma characterization.
authors: Department of Ultrasound, Institute of Fundamental Technological Research, Warsaw, Poland. Electronic address: hpiotrzk@ippt.pan.pl.
authors: Hanna
authors: H
authors: Piotrzkowska-Wroblewska
authors: Department of Ultrasound, Institute of Fundamental Technological Research, Warsaw, Poland.
authors: Jerzy
authors: J
authors: Litniewski
authors: Dermatology Clinic, CSK MSWiA Hospital, Warsaw, Poland.
authors: Elzbieta
authors: E
authors: Szymanska
authors: Department of Ultrasound, Institute of Fundamental Technological Research, Warsaw, Poland.
authors: Andrzej
authors: A
authors: Nowicki
mesh_terms: D002280:Basal Cell Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D012878:Skin Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D014463:Ultrasonography
keywords: Attenuation coefficient; High frequency; Human skin; K-distribution; Quantitative ultrasound; Skin lesions; Tissue characterization