title: Effect of moderate and high resistance training intensity on indices of inflammatory and oxidative stress.
abstract: This study was designed to examine the effect of moderate (MR) and high resistance (HR) training on systemic inflammation and circulating enzymatic antioxidant activity. Thirty males were assigned to HR (n = 10), MR (n = 10), or control (C; n = 10) groups. Resistance training was performed for eight weeks. Activities of superoxide dismutase (SOD), glutathione peroxidase (GPX), creatine kinase (CK), and concentrations of malondialdehyde (MDA), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) were measured before and after training in plasma. The results show increased SOD activity in MR (p = 0.026) and HR (p = 0.044) groups. GPX activity in HR (p = 0.012) and MR (p = 0.037) increased significantly more than in C. Whilst a significant reduction in MDA in MR (p = 0.013) and HR (p = 0.023) was observed compared with C, no significant difference in IL-6, TNF-α and CK occurred between groups. We conclude that changes in enzymatic antioxidant defense and inflammatory markers following resistance training are independent of training intensity.
authors: a Exercise Physiology Department, Faculty of Physical Education , Islamic Azad University, Sannadaj Branch , Iran.
authors: Kamal
authors: K
authors: Azizbeigi
authors: Mohammad Ali
authors: MA
authors: Azarbayjani
authors: Sirvan
authors: S
authors: Atashak
authors: Stephen R
authors: SR
authors: Stannard
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D015415:Biomarkers / Q000097:blood; D016207:Cytokines / Q000097:blood; D064368:Healthy Volunteers; D006801:Humans; D007249:Inflammation / Q000378:metabolism*; D008297:Male; D018384:Oxidative Stress; D055070:Resistance Training / Q000379:methods*
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D016207:Cytokines
keywords: antioxidant defense; inflammation; resistance training