title: Evaluation of effectiveness of herbal medication in cancer care: a review study.
abstract: Based on a common belief, herbal medicine with the least possible side effects should be the center of attention in cancer care; however, in many cases they have not been properly studied with reliable clinical trials in human subjects. In this review, it was attempted to identify the available evidence on the use and clinical effects of herbs in cancer care. The research consists of two major parts including immunomodulator and chemopreventive herbal compounds whose mechanism, biological response, anticancer element of extract and related benefits were completely studied. Also, the safety of herbal anticancer compounds was discussed. Although the use of herbal medicines in treating cancer shows less chemotherapy-induced, toxicity, more researches are required to reach their full therapeutic potentials.
authors: Dept. of Biomedical Engineering, Biomedical Engineering Faculty, Science and Research Branch of Islamic Azad University, Tehran, Iran.
authors: Javad
authors: J
authors: Tavakoli
authors: Dept. of Biomedical Engineering, Biomedical Engineering Faculty, Science and Research Branch of Islamic Azad University, Tehran, Iran.
authors: Solaleh
authors: S
authors: Miar
authors: Dept. of Biomedical Engineering, Biomedical Engineering Faculty, Science and Research Branch of Islamic Azad University, Tehran, Iran.
authors: Mohammad
authors: M
authors: Majid Zadehzare
authors: Dept. of Biomedical Engineering, Biomedical Engineering Faculty, Science and Research Branch of Islamic Azad University, Tehran, Iran.
authors: Hossein
authors: H
authors: Akbari
keywords: Immunologic factors; Neoplasms; Plants; Prevention; Safety
references: S Afr Med J. 2007 Oct;97(10):937, 939
references: 18000571
references: Carcinogenesis. 2002 Jan;23(1):143-50
references: 11756235
references: Circulation. 2004 Sep 7;110(10 ):1219-25
references: 15337705
references: Ann N Y Acad Sci. 2005 Nov;1056:206-17
references: 16387689
references: Eur J Cancer. 2006 Aug;42(12):1702-10
references: 16790340
references: J Health Soc Policy. 2003;16(4):75-84
references: 12943333
references: Int J Cancer. 2005 Oct 20;117(1):1-7
references: 15880398
references: Methods Mol Med. 2005;111:69-78
references: 15911972
references: Semin Oncol Nurs. 2005 Aug;21(3):177-83
references: 16092805
references: Zhonghua Zhong Liu Za Zhi. 1994 May;16(3):167-71
references: 7956691
references: Mol Cancer Ther. 2005 Feb;4(2):233-41
references: 15713895
references: Curr Pharm Des. 2001 Sep;7(13):1181-97
references: 11472261
references: Life Sci. 2004 Sep 17;75(18):2233-44
references: 15325848
references: Int Immunopharmacol. 2006 Mar;6(3):499-508
references: 16428086
references: Semin Oncol. 2006 Aug;33(4):421-35
references: 16890797
references: Ann Oncol. 2006 May;17 (5):735-49
references: 16364960
references: Cancer. 2005 Aug 15;104(4):879-90
references: 16007726
references: J Biol Response Mod. 1983;2(3):227-37
references: 6644339
references: Breast Cancer Res Treat. 2010 Nov;124(1):265-77
references: 20490654
references: Oncogene. 2004 Dec 9;23(57):9247-58
references: 15489888
references: Cancer Lett. 2005 Jun 8;223(2):181-90
references: 15896452
references: Blood. 2004 Apr 15;103(8):3175-84
references: 15070700
references: Immunol Invest. 2003 Aug;32(3):201-15
references: 12916709
references: Int J Cancer. 2004 Sep 20;111(5):679-92
references: 15252836
references: Ann N Y Acad Sci. 2004 Dec;1030:434-41
references: 15659827
references: Cochrane Database Syst Rev. 2007 Jan 24;(1):CD004520
references: 17253513
references: J Clin Oncol. 2002 Sep 15;20(18 Suppl):34S-8S
references: 12235222
references: J Ethnopharmacol. 2006 Apr 21;105(1-2):263-8
references: 16361073
references: Expert Opin Investig Drugs. 2004 Oct;13(10):1327-38
references: 15461561
references: J Immunol. 2004 May 15;172(10 ):5940-7
references: 15128775
references: Breast Cancer Res Treat. 2005 Apr;90(3):233-9
references: 15830136
references: Cancer Detect Prev. 2003;27(2):147-54
references: 12670527
references: J Nutr. 2001 Mar;131(3s):1120S-3S
references: 11238830
references: Eur J Biochem. 1996 Nov 15;242(1):1-19
references: 8954147
references: Int J Oncol. 2010 Feb;36(2):395-403
references: 20043074
references: Breast Cancer Res Treat. 2011 Jul;128(1):57-68
references: 20665104
references: Lancet. 2000 May 20;355(9217):1822
references: 10832853
references: Oncogene. 2001 Nov 15;20(52):7597-609
references: 11753638
references: J Cancer Res Clin Oncol. 2011 Jul;137(7):1117-22
references: 21298288
references: Breast Cancer Res Treat. 2010 May;121(1):233-40
references: 19760501
references: Toxicol Appl Pharmacol. 2007 Nov 1;224(3):274-83
references: 17306316
references: Blood. 2003 Feb 1;101(3):1053-62
references: 12393461
references: Int J Cancer. 1997 Mar 17;70(6):699-705
references: 9096652
references: Br J Nutr. 2004 Feb;91(2):263-9
references: 14756912
references: Breast Cancer Res Treat. 2007 Jan;101(1):27-36
references: 17028990
references: Plant Foods Hum Nutr. 2011 Nov;66(4):328-34
references: 21964875
references: Pharmacol Res. 2009 Jun;59(6):365-78
references: 19429468
references: Support Care Cancer. 2002 Oct;10(7):542-8
references: 12324809
references: Altern Ther Health Med. 1999 Jan;5(1):71-6
references: 9893318
references: Altern Ther Health Med. 2004 Jan-Feb;10(1):52-7
references: 14727500
references: Life Sci. 2004 Nov 26;76(2):191-200
references: 15519364
references: J Med Assoc Thai. 2003 Jan;86(1):61-8
references: 12678140
references: Biochem Pharmacol. 2005 Sep 1;70(5):700-13
references: 16023083
references: Carcinogenesis. 2003 Jul;24(7):1269-79
references: 12807725
references: Crit Rev Immunol. 1999;19(1):65-96
references: 9987601
references: Int J Biochem Cell Biol. 2006;38(8):1249-53
references: 16314136
references: Cell Biol Int. 2007 Aug;31(8):851-5
references: 17418594
references: Eur J Cancer. 2011 Mar;47(4):508-14
references: 21185719
references: J Ethnopharmacol. 2011 Sep 1;137(1):752-66
references: 21763411
references: Leuk Res. 1999 Jan;23(1):43-50
references: 9933134
references: Immunol Invest. 2005;34(2):171-98
references: 15921158
references: Cancer Lett. 2004 Nov 25;215(2):129-40
references: 15488631
references: Am J Surg. 2000 May;179(5):407-11
references: 10930491
references: J Immunol. 2003 Oct 1;171(7):3863-71
references: 14500688
references: Eur J Cancer. 2000 Jul;36(11):1359-64
references: 10899648
references: JAMA. 1998 Apr 15;279(15):1200-5
references: 9555760
references: Jpn J Clin Oncol. 2002 Mar;32 Suppl:S82-91
references: 11959881
references: Anticancer Res. 2003 Jan-Feb;23(1A):363-98
references: 12680238
references: Integr Cancer Ther. 2002 Sep;1(3):287-93; discussion 293
references: 14667286
references: J Zhejiang Univ Sci B. 2006 Dec;7(12):1006-14
references: 17111471
references: Cancer. 2004 Nov 15;101(10 ):2351-62
references: 15476283
references: J Clin Lab Immunol. 1988 Mar;25(3):119-23
references: 3260960
references: Oncogene. 2002 Dec 12;21(57):8852-61
references: 12483537
references: Cancer Lett. 2007 Oct 8;255(2):170-81
references: 17448598
references: J Clin Pharmacol. 2007 May;47(5):579-88
references: 17442684
references: Altern Ther Health Med. 2003 Sep-Oct;9(5):38-52
references: 14526710