title: Metabolomic applications in nutritional research: a perspective.
abstract: Metabolomics focuses on the global study of metabolites in cells, tissues and biofluids. Analytical technologies such as nuclear magnetic resonance (NMR) spectroscopy and hyphenated mass spectrometry (MS) combined with advanced multivariate statistical methods allow us to study perturbations in metabolism. The close link between metabolism and nutrition has seen the application of metabolomics in nutritional research increase in recent times. Such applications can be divided into three main categories, namely (1) the area of dietary biomarker identification, (2) diet-related diseases and (3) nutritional interventions. The present perspective gives an overview of these applications and an outlook to the future.
authors: UCD School of Agriculture and Food Science, Institute of Food and Health, UCD Conway Institute, Belfield, Dublin 4, Ireland.
authors: Aoife
authors: A
authors: O'Gorman
authors: UCD School of Agriculture and Food Science, Institute of Food and Health, UCD Conway Institute, Belfield, Dublin 4, Ireland.|Institute of Health and Society, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK.
authors: Lorraine
authors: L
authors: Brennan
mesh_terms: D015415:Biomarkers; D035843:Biomedical Research / Q000379:methods*; D004032:Diet; D005247:Feeding Behavior; D006801:Humans; D055442:Metabolome; D055432:Metabolomics / Q000379:methods*; D052756:Nutritional Sciences / Q000379:methods*
chemical_list: D015415:Biomarkers
keywords: biomarkers; diet-related disease; dietary intervention; metabolomics; nutrition