title: Long-term cancer-free survival after infusion of autologous cord blood cells for rejection-unrelated cord blood graft after myeloablative conditioning for t-MDS: a case report.
abstract: Autologous cord blood transplantations are rarely applied in patients with hematologic as well as metastatic solid cancers since contamination of malignant clones is a concern. We report a case of therapy-related myelodysplasia after metastatic neuroblastoma who suffered from graft rejection and life-threatening infections after a myeloablative unrelated cord blood transplantation. The patient experiences long-term survival, free from leukemia/neuroblastoma after infusion of autologous cord blood cells. It suggests that autologous cord blood transplantation after high dose therapy might be a curative strategy for certain hematologic or metastatic solid cancers.
authors: From the Departments of Internal Medicine (W-TC); Pharmacy (L-HF); and Pediatric Hematology and Oncology (R-LC), Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan.
authors: Wei-Ting
authors: WT
authors: Chen
authors: Li-Hua
authors: LH
authors: Fang
authors: Rong-Long
authors: RL
authors: Chen
mesh_terms: D002675:Child, Preschool; D005260:Female; D005312:Fetal Blood; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans; D007166:Immunosuppressive Agents; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D009190:Myelodysplastic Syndromes / Q000628:therapy*; D009447:Neuroblastoma
chemical_list: D007166:Immunosuppressive Agents
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