title: A case of retinoblastoma metastasizing to the mandible and review of literature.
abstract: OBJECTIVE
  The aim of this case report and review was to determine the characteristics of retinoblastoma.
  
  
  METHODS
  One case report was introduced along with previous reports on retinoblastoma metastasizing to the mandible.
  
  
  RESULTS
  Sixteen cases from 14 reports were included in this study. Including the present case, 11 of 16 patients died within 8 months.
  
  
  CONCLUSIONS
  Retinoblastoma rarely metastasizes to the mandible. However, metastasis to other organs should be considered, and specialists should be consulted if retinoblastoma metastasis to the mandible is observed. Moreover, it is necessary to follow up patients after multidisciplinary therapy is completed, because subsequent complications of the teeth and jawbones associated with therapy could occur.
authors: a Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences , University of Fukui , Japan.
authors: Seigo
authors: S
authors: Ohba
authors: b Department of Pediatrics, Faculty of Medical Sciences , University of Fukui , Japan.
authors: Akihiko
authors: A
authors: Tanizawa
authors: a Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences , University of Fukui , Japan.
authors: Hitoshi
authors: H
authors: Yoshimura
authors: a Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences , University of Fukui , Japan.
authors: Shinpei
authors: S
authors: Matsuda
authors: c Division of Surgical Pathology , University of Fukui Hospital.
authors: Yoshiaki
authors: Y
authors: Imamura
authors: a Division of Dentistry and Oral Surgery, Department of Sensory and Locomotor Medicine, Faculty of Medical Sciences , University of Fukui , Japan.
authors: Kazuo
authors: K
authors: Sano
mesh_terms: D002675:Child, Preschool; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D019572:Retinal Neoplasms / Q000473:pathology*; D012175:Retinoblastoma / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D016896:Treatment Outcome
keywords: Mandible; Metastasis; Multidisciplinary therapy; Peripheral blood stem cell transplantation; Retinoblastoma