title: Electrochemical intramolecular C-H amination: synthesis of benzoxazoles and benzothiazoles.
abstract: A new method for metal-free intramolecular C-H amination has been developed. Electrochemical oxidation of 2-pyrimidyloxybenzenes and 2-pyrimidylthiobenzenes, which can be easily prepared from phenols and thiophenols, respectively, followed by the treatment of the resulting pyrimidinium ions with piperidine gives 2-aminobenzoxazoles and 2-aminobenzothiazoles, respectively.
authors: Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510 (Japan).
authors: Tatsuya
authors: T
authors: Morofuji
authors: Akihiro
authors: A
authors: Shimizu
authors: Jun-Ichi
authors: J
authors: Yoshida
keywords: CH amination; CH functionalization; electrochemistry; oxidation; radical ions