title: [Metabolic syndrome risk assessment in children: use of a single score].
abstract: OBJECTIVE
  To calculate a score of metabolic syndrome (MetS) in children and set a cutoff point of this score for the prediction of MetS risk.
  
  
  METHODS
  The study included a random sample of 348 children aged 8 and 9 years of Viçosa, Southeast Brazil. Factor analysis by principal components (PCA) was used to determine, among various risk factors, those with higher degrees of intercorrelation. The chosen variables were: waist circumference (PC), homeostatic model assessment of insulin resistance (HOMA), high density lipoprotein (HDL), triglycerides (TAG) and mean arterial pressure (MAP). Z-scores were created for each one of these parameters and the sum of these z-scores constituted the MetS score. The receiver operating characteristic (ROC) curve was used to identify the cutoff of MetS score, using as gold standard the presence or absence of MetS determined according to criteria age-modified.
  
  
  RESULTS
  The prevalence of MetS in the sample was 8.9% by adopting specific criteria for age, and 24% when considering the cutoff of MetS score. The selected cutoff point of 1.86 was accurate to predict the MetS risk in this sample due to its high sensitivity (96.7%), specificity (82.7%) and AUC of 0.96.
  
  
  CONCLUSIONS
  This original Brazilian study presents the MetS score as a suitable alternative for the study of Metabolic Syndrome in children, given the lack of consensus for the definition of this syndrome in childhood.
authors: Universidade Federal de Viçosa (UFV), Viçosa, MG, Brasil. Electronic address: juliakhede@hotmail.com.
authors: Julia Khéde Dourado
authors: JK
authors: Villa
authors: Universidade Federal de Viçosa (UFV), Viçosa, MG, Brasil.
authors: Angélica Ribeiro E
authors: AR
authors: Silva
authors: Universidade Federal de Viçosa (UFV), Viçosa, MG, Brasil.
authors: Thanise Sabrina Souza
authors: TS
authors: Santos
authors: Universidade Federal de Viçosa (UFV), Viçosa, MG, Brasil.
authors: Andréia Queiroz
authors: AQ
authors: Ribeiro
authors: Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brasil.
authors: Luciana Ferreira da Rocha
authors: LF
authors: Sant'Ana
mesh_terms: D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D018570:Risk Assessment
keywords: Children; Crianças; Escore; Metabolic syndrome; Score; Síndrome metabólica
references: Rev Esc Enferm USP. 2008 Mar;42(1):120-6
references: 18450156
references: Diabet Med. 2000 Feb;17(2):152-7
references: 10746487
references: Arq Bras Cardiol. 2011 Feb;96(2):121-5
references: 21243313
references: Int J Obes (Lond). 2005 Sep;29(9):1077-83
references: 15917844
references: Diabetes Care. 2006 Jan;29(1):113-22
references: 16373906
references: Clin Chem. 1972 Jun;18(6):499-502
references: 4337382
references: Circulation. 2004 Oct 19;110(16):2494-7
references: 15477412
references: Pediatrics. 2007 Nov;120(5):e1262-8
references: 17974719
references: Diabetes Care. 2007 Jun;30(6):1556-61
references: 17363752
references: J Clin Epidemiol. 2001 Feb;54(2):190-5
references: 11166535
references: Arq Bras Cardiol. 2005 Dec;85 Suppl 6:4-36
references: 16597097
references: Arch Pediatr Adolesc Med. 2003 Aug;157(8):821-7
references: 12912790
references: Acta Paediatr. 2006 Aug;95(8):1005-11
references: 16882578
references: Diabetes Care. 2002 Oct;25(10):1790-4
references: 12351479
references: Diabetes Care. 2005 Sep;28(9):2289-304
references: 16123508
references: JAMA. 2004 Sep 22;292(12):1440-6
references: 15383514
references: Diabetes Care. 2002 Jul;25(7):1203-10
references: 12087020
references: Diabet Med. 2006 May;23(5):469-80
references: 16681555
references: Cardiovasc Diabetol. 2008 Jun 05;7:17
references: 18534019
references: Diabetes Care. 2006 Oct;29(10):2329
references: 17003322
references: Circulation. 1997 Dec 16;96(12):4319-25
references: 9416899
references: Ann Epidemiol. 2010 Nov;20(11):843-51
references: 20933191
references: Diabetes Care. 2010 Jun;33(6):1370-2
references: 20299487
references: Science. 1988 Jun 3;240(4857):1285-93
references: 3287615
references: Diabetol Metab Syndr. 2010 Jan 28;2:8
references: 20181030