title: A surface-acoustic-wave-based cantilever bio-sensor.
abstract: A scalable surface-acoustic-wave- (SAW-) based cantilevered device for portable bio-chemical sensing applications is presented. Even in the current, proof-of-principle implementation this architecture is shown to outperform commercial quartz-crystal microbalances in terms of sensitivity. Adhesion of analytes on a functionalized surface of the cantilever shifts the resonant frequency of a SAW-generating transducer due to the stress-induced variation of the speed of surface acoustic modes. We discuss the relevance of this approach for diagnostics applications based on miniaturized devices.
authors: Center for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia, Piazza San Silvestro 12, I-56127 Pisa, Italy. Electronic address: giorgio.desimoni@iit.it.
authors: Giorgio
authors: G
authors: De Simoni
authors: Center for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia, Piazza San Silvestro 12, I-56127 Pisa, Italy.
authors: Giovanni
authors: G
authors: Signore
authors: Center for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia, Piazza San Silvestro 12, I-56127 Pisa, Italy; NEST, Scuola Normale Superiore, Piazza San Silvestro 12, I-56127 Pisa, Italy.
authors: Matteo
authors: M
authors: Agostini
authors: NEST, Scuola Normale Superiore, Piazza San Silvestro 12, I-56127 Pisa, Italy.
authors: Fabio
authors: F
authors: Beltram
authors: Center for Nanotechnology Innovation @NEST, Istituto Italiano di Tecnologia, Piazza San Silvestro 12, I-56127 Pisa, Italy.
authors: Vincenzo
authors: V
authors: Piazza
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D006801:Humans; D057089:Pathology, Molecular / Q000295:instrumentation; D058525:Quartz Crystal Microbalance Techniques / Q000295:instrumentation*; D013016:Sound
keywords: Cantilever bio-sensor; Surface acoustic wave