title: Curing advanced melanoma by 2025.
abstract: OBJECTIVE
  To outline the most urgent challenges in the management of advanced melanoma.
  
  
  RESULTS
  Considerable progress in targeted and immunotherapy of advanced melanoma has opened a perspective for a cure if all molecular and medical information is integrated in a rational precision treatment algorithm.
  
  
  CONCLUSIONS
  Bioinformatics and system biology approaches will be needed to deal with omics databases. The support of patient advocacy groups may help to increase the acceptance of large scale, routine biobanking.
authors: Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
authors: Reinhard
authors: R
authors: Dummer
authors: Simone M
authors: SM
authors: Goldinger
authors: Verena
authors: V
authors: Paulitschke
authors: Mitchell P
authors: MP
authors: Levesque
mesh_terms: D000465:Algorithms; D019295:Computational Biology; D006801:Humans; D007167:Immunotherapy / Q000639:trends; D008545:Melanoma / Q000188:drug therapy* / Q000517:prevention & control; D058990:Molecular Targeted Therapy / Q000639:trends