title: Use of fructosyl peptide oxidase for HbA1c assay.
abstract: ARKRAY, Inc developed the world's first automatic glycohemoglobin analyzer based on HPLC (1981). After that, ARKRAY developed enzymatic HbA1c assay "CinQ HbA1c" with the spread and diversification of HbA1c measurement (2007). CinQ HbA1c is the kit of Clinical Chemistry Analyzer, which uses fructosyl peptide oxidase (FPOX) for a measurement reaction. This report mainly indicates the developmental background, measurement principle, and future of the enzymatic method HbA1c reagent.
authors: ARKRAY, Inc., Kyoto, Japan yonehara@arkray.co.jp.
authors: Satoshi
authors: S
authors: Yonehara
authors: ARKRAY, Inc., Kyoto, Japan.
authors: Norio
authors: N
authors: Inamura
authors: ARKRAY, Inc., Kyoto, Japan.
authors: Miho
authors: M
authors: Fukuda
authors: ARKRAY, Inc., Kyoto, Japan.
authors: Koji
authors: K
authors: Sugiyama
mesh_terms: D000594:Amino Acid Oxidoreductases / Q000097:blood*; D001774:Blood Chemical Analysis / Q000266:history / Q000379:methods*; D003920:Diabetes Mellitus / Q000097:blood*; D057075:Enzyme Assays / Q000266:history; D006442:Glycated Hemoglobin / Q000032:analysis*; D049673:History, 20th Century; D006801:Humans; D011933:Reagent Kits, Diagnostic / Q000266:history
chemical_list: D000594:Amino Acid Oxidoreductases; D006442:Glycated Hemoglobin; D011933:Reagent Kits, Diagnostic; C520096:fructosyl-peptide oxidase
keywords: FPOX; HbA1c; enzymatic method; glycated hemoglobin
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