title: The impact of a pre-loaded multi-ingredient performance supplement on muscle soreness and performance following downhill running.
abstract: The effects of multi-ingredient performance supplements (MIPS) on perceived soreness, strength, flexibility and vertical jump performance following eccentric exercise are unknown. The purpose of this study was to determine the impact of MIPS (NO-Shotgun®) pre-loaded 4 weeks prior to a single bout of downhill running (DHR) on muscle soreness and performance. Trained male runners (n = 20) were stratified by VO2max, strength, and lean mass into two groups; MIPS (n = 10) ingested one serving daily of NO-Shotgun® for 28 days and 30 min prior to all post-testing visits, Control (CON; n = 10) consumed an isocaloric maltodextrin placebo in an identical manner as MIPS. Perceived soreness and performance measurements (strength, flexibility, and jump height) were tested on 6 occasions; 28 days prior to DHR, immediately before DHR (PRE), immediately post (POST) DHR, 24, 48, and 72 hr post-DHR. Perceived soreness significantly increased (p < 0.05) post DHR compared to PRE at all time-points, with no difference between groups. Creatine kinase (CK) and lactate dehydrogenase (LDH) increased over time (p < 0.001) with no group x time interactions (p = 0.236 and p = 0.535, respectively). Significant time effects were measured for strength (p = 0.001), flexibility (p = 0.025) and vertical jump (p < 0.001). There were no group x time interactions for any performance measurements. Consumption of MIPS for 4 weeks prior to a single bout of DHR did not affect perceived soreness, muscle damage, strength, flexibility, or jump performance compared to an isocaloric placebo in trained male runners following a single bout of DHR.
authors: Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL USA ; Institute of Sports Sciences and Medicine, Florida State University, Tallahassee, FL USA ; Discipline of Biokinetics, Exercise and Leisure Sciences, University of KwaZulu-Natal, Durban, South Africa.
authors: Michael J
authors: MJ
authors: Ormsbee
authors: Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL USA.
authors: Emery G
authors: EG
authors: Ward
authors: Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL USA ; Institute of Sports Sciences and Medicine, Florida State University, Tallahassee, FL USA.
authors: Christopher W
authors: CW
authors: Bach
authors: Human Nutrition and Metabolism Laboratory, Skidmore College, Saratoga Springs, NY USA.
authors: Paul J
authors: PJ
authors: Arciero
authors: Discipline of Biokinetics, Exercise and Leisure Sciences, University of KwaZulu-Natal, Durban, South Africa.
authors: Andrew J
authors: AJ
authors: McKune
authors: Department of Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL USA.
authors: Lynn B
authors: LB
authors: Panton
keywords: Eccentric exercise; Muscle damage; Recovery
references: Exerc Sport Sci Rev. 2005 Apr;33(2):98-104
references: 15821431
references: Int J Sport Nutr Exerc Metab. 2007 Dec;17(6):595-607
references: 18156664
references: Br Med Bull. 2007;81-82:209-30
references: 17569697
references: Med Sci Sports Exerc. 1992 May;24(5):512-20
references: 1569847
references: Histochem Cell Biol. 2002 Jul;118(1):29-34
references: 12122444
references: J Int Soc Sports Nutr. 2012 Nov 15;9(1):49
references: 23153110
references: Clin Sci (Lond). 1988 Sep;75(3):257-61
references: 3416560
references: Int J Sport Nutr Exerc Metab. 2010 Jun;20(3):236-44
references: 20601741
references: Int J Sports Physiol Perform. 2010 Mar;5(1):18-26
references: 20308693
references: J Sports Sci. 2009 Sep;27(11):1137-44
references: 19714546
references: Life Sci. 2004 Sep 3;75(16):1917-24
references: 15306159
references: J Int Soc Sports Nutr. 2010 Sep 22;7:30
references: 20860817
references: Amino Acids. 2012 May;42(5):1987-96
references: 21562819
references: J Muscle Res Cell Motil. 2012 Aug;33(3-4):177-85
references: 22673937
references: Br J Nutr. 2004 Jan;91(1):161-8
references: 14748950
references: Int J Sport Nutr Exerc Metab. 2006 Dec;16(6):620-35
references: 17342883
references: J Strength Cond Res. 2001 May;15(2):178-84
references: 11710402
references: Chin J Physiol. 2011 Apr 30;54(2):71-8
references: 21789887
references: Med Sci Sports Exerc. 2010 May;42(5):962-70
references: 19997002
references: J Sports Sci. 2007 Jan 1;25(1):55-63
references: 17127581
references: Eur J Appl Physiol. 2005 Mar;93(5-6):606-13
references: 15578203
references: J Int Soc Sports Nutr. 2012 Jul 12;9:20
references: 22569039
references: J Sports Med Phys Fitness. 2000 Sep;40(3):240-6
references: 11125767
references: Med Sci Sports Exerc. 2003 Jun;35(6):930-6
references: 12783040
references: J Strength Cond Res. 2007 Nov;21(4):1208-13
references: 18076246
references: Histochem Cell Biol. 2012 Jul;138(1):89-99
references: 22487949
references: J Int Soc Sports Nutr. 2009 Jun 02;6:13
references: 19490606
references: Amino Acids. 2010 Mar;38(3):771-8
references: 19347247
references: Appl Physiol Nutr Metab. 2008 Jun;33(3):483-8
references: 18461101
references: J Appl Physiol (1985). 1995 Feb;78(2):702-8
references: 7759443
references: Nutr Metab (Lond). 2011 Nov 03;8:78
references: 22050827
references: Scand J Med Sci Sports. 2001 Apr;11(2):126-7
references: 11252462
references: J Int Soc Sports Nutr. 2009 Aug 05;6:16
references: 19656392
references: PLoS One. 2013 Apr 15;8(4):e62056
references: 23614012