title: Comparisons of thyroid hormone, intelligence, attention, and quality of life in children with obstructive sleep apnea hypopnea syndrome before and after endoscopic adenoidectomy.
abstract: Objective. The aim of this study was to compare the differences in thyroid hormone, intelligence, attention, and quality of life (QoL) of children with obstructive sleep apnea hypopnea syndrome (OSAHS) before and after endoscopic adenoidectomy. Method. A total of 35 OSAHS children (21 males and 14 females with a mean age of 6.81 ± 1.08 years) were included in this study for analyzing the levels of thyroid hormone, intelligence, attention, and QoL. There were 22 children underwent endoscopic adenoidectomy with bilateral tonsillectomy (BT), while the other 13 children who underwent endoscopic adenoidectomy without bilateral tonsillectomy without BT. Results. Our results revealed no significant difference in serum free triiodothyronine (FT3), free thyroxine (FT4), and thyroid stimulating hormone (TSH) levels in OSAHS children before and after endoscopic adenoidectomy (all P > 0.05). However, there were significant differences in full-scale intelligence quotient (FIQ) (92.45 ± 5.88 versus 106.23 ± 7.39, P < 0.001), verbal intelligence quotient (VIQ) (94.17 ± 15.01 versus 103.91 ± 9.74, P = 0.006), and performance intelligence quotient (PIQ) (94.12 ± 11.04 versus 104.31 ± 10.05, P = 0.001), attention (98.48 ± 8.74 versus 106.87 ± 8.58, P < 0.001), and total OSA-18 scores (87.62 ± 17.15 versus 46.61 ± 10.15, P < 0.001) between before and after endoscopic adenoidectomy in OSAHS children. Conclusion. Our findings provided evidence that the intelligence, attention, and QoL of OSAHS children may be significantly improved after endoscopic adenoidectomy.
authors: Department of Otorhinolaryngology, The Second Hospital of Shandong University, Jinan 250000, China.
authors: Hui-Wei
authors: HW
authors: Feng
authors: Department of Otorhinolaryngology, Dezhou Municipal Hospital, Dezhou 253000, China.
authors: Tao
authors: T
authors: Jiang
authors: Department of Otorhinolaryngology, The Second Hospital of Shandong University, Jinan 250000, China.
authors: Hong-Ping
authors: HP
authors: Zhang
authors: Department of Otorhinolaryngology, The Second Hospital of Shandong University, Jinan 250000, China.
authors: Zhe
authors: Z
authors: Wang
authors: Department of Otorhinolaryngology, The Second Hospital of Shandong University, Jinan 250000, China.
authors: Hai-Ling
authors: HL
authors: Zhang
authors: Department of Otorhinolaryngology, The Second Hospital of Shandong University, Jinan 250000, China.
authors: Hui
authors: H
authors: Zhang
authors: Department of Otorhinolaryngology, The Second Hospital of Shandong University, Jinan 250000, China.
authors: Xue-Mei
authors: XM
authors: Chen
authors: Department of Otorhinolaryngology, The Second Hospital of Shandong University, Jinan 250000, China.
authors: Xian-Liang
authors: XL
authors: Fan
authors: Department of Orthopedic Surgery, The First Hospital of Jinan, Jinan 250000, China.
authors: Yu-Dong
authors: YD
authors: Tian
authors: Department of Otorhinolaryngology, The Second Hospital of Shandong University, Jinan 250000, China.
authors: Tao
authors: T
authors: Jia
mesh_terms: D000233:Adenoidectomy; D001288:Attention; D016022:Case-Control Studies; D002648:Child; D004724:Endoscopy; D005260:Female; D006801:Humans; D007360:Intelligence; D008297:Male; D011788:Quality of Life; D020181:Sleep Apnea, Obstructive / Q000097:blood* / Q000503:physiopathology*; D013963:Thyroid Hormones / Q000097:blood*; D014068:Tonsillectomy
chemical_list: D013963:Thyroid Hormones
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