title: [Contributions of proteomics in the study of diabetes].
abstract: The incidence of type 2 diabetes mellitus (T2D) is growing rapidly due to aging, urbanization, changes in lifestyle, and increasing prevalence of obesity. In T2D, chronic hyperglycemia leads to macro and micro vascular complications, which currently are serious problem for health systems worldwide. The complexity of T2D and its complications requires study skills of high performance that provide important information in the understanding of the pathophysiology of the disease and biological pathways involved in development of T2D and its complications. In this work we describe the recent contributions of proteomics in the study of T2D and discuss its importance in the identification of therapeutic targets and biomarkers that help to improve the diagnosis of T2D, monitor the disease progression, and the development of new drugs to improve treatment and reduce its complications.
authors: Departamento de Ciencias Médicas, División de Ciencias de la Salud, Campus León, Universidad de Guanajuato, León, Gto.
authors: Lizbeth M
authors: LM
authors: Jiménez-Flores
authors: Departamento de Ciencias Médicas, División de Ciencias de la Salud, Campus León, Universidad de Guanajuato, León, Gto.
authors: Elsa Cristina
authors: EC
authors: Flores-Pérez
authors: Departamento de Ciencias Médicas, División de Ciencias de la Salud, Campus León, Universidad de Guanajuato, León, Gto.
authors: Daniela Paulina
authors: DP
authors: Mares-Álvarez
authors: Departamento de Ciencias Médicas, División de Ciencias de la Salud, Campus León, Universidad de Guanajuato, León, Gto.
authors: Maciste Habacuc
authors: MH
authors: Macías-Cervantes
authors: Departamento de Ciencias Médicas, División de Ciencias de la Salud, Campus León, Universidad de Guanajuato, León, Gto.
authors: Joel
authors: J
authors: Ramírez-Emiliano
authors: Departamento de Ciencias Médicas, División de Ciencias de la Salud, Campus León, Universidad de Guanajuato, León, Gto.
authors: Victoriano
authors: V
authors: Pérez-Vázquez