title: Quality of life and migraine disability among female migraine patients in a tertiary hospital in Malaysia.
abstract: BACKGROUND
  Disability caused by migraine may be one of the main causes of burden contributing to poor quality of life (QOL) among migraine patients. Thus, this study aimed to measure QOL among migraine sufferers in comparison with healthy controls.
  
  
  METHODS
  Female diagnosed migraine patients (n= 100) and healthy controls (n=100) completed the Malay version of the World Health Organization QOL Brief (WHOQOL-BREF) questionnaire. Only migraine patients completed the Malay version of the Migraine Disability Assessment questionnaire.
  
  
  RESULTS
  Females with migraines had significantly lower total WHOQOL-BREF scores (84.3) than did healthy controls (91.9, P<0.001). Similarly, physical health (23.4 versus 27.7, P<0.001) and psychological health scores (21.7 versus 23.2, P< 0.001) were significantly lower than those for healthy controls. Seventy-three percent of patients experienced severe disability, with significantly higher number of days with headaches (13.8 days/3 months, P< 0.001) and pain scores (7.4, P< 0.013). Furthermore, migraine patients with lower total QOL scores had 1.2 times higher odds of having disability than patients with higher total QOL scores.
  
  
  CONCLUSIONS
  The present study showed that migraine sufferers experienced significantly lower QOL than the control group from a similar population. Disability was severe and frequent and was associated with lower QOL among the migraine patients.
authors: Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
authors: Munvar Miya
authors: MM
authors: Shaik
authors: Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
authors: Norul Badriah
authors: NB
authors: Hassan
authors: Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
authors: Huay Lin
authors: 0000-0002-6670-2668
authors: HL
authors: Tan
authors: Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
authors: Siew Hua
authors: SH
authors: Gan
mesh_terms: D000328:Adult; D003710:Demography; D004185:Disability Evaluation; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008296:Malaysia / Q000453:epidemiology; D008875:Middle Aged; D008881:Migraine Disorders / Q000453:epidemiology*; D011788:Quality of Life; D011795:Surveys and Questionnaires; D062606:Tertiary Care Centers / Q000706:statistics & numerical data*; D014944:World Health Organization
references: J Clin Neurol. 2012 Sep;8(3):198-203
references: 23091529
references: Headache. 1993 Jul-Aug;33(7):351-8
references: 8376093
references: Prim Care. 2004 Jun;31(2):417-28, viii
references: 15172516
references: CNS Drugs. 2009 Dec;23(12):1039-45
references: 19958041
references: Neurology. 1998 Jun;50(6):1741-5
references: 9633720
references: Cephalalgia. 2007 Mar;27(3):193-210
references: 17381554
references: J Am Med Womens Assoc (1972). 2002 Spring;57(2):73-8
references: 11991424
references: Cephalalgia. 2004 Jun;24(6):455-65
references: 15154855
references: Biomed Res Int. 2014;2014:435856
references: 25121099
references: Neurol India. 2013 Jul-Aug;61(4):355-9
references: 24005724
references: Mayo Clin Proc. 2009 May;84(5):422-35
references: 19411439
references: Headache. 2001 Oct;41(9):854-61
references: 11703471
references: Cephalalgia. 2003 Jul;23(6):441-50
references: 12807523
references: Can J Neurol Sci. 1993 May;20(2):131-7
references: 8334575
references: Pain. 2000 May;86(1-2):139-49
references: 10779671
references: Headache. 1994 Jun;34(6):337-43
references: 7928312
references: J Fam Pract. 2002 Feb;51(2):142-7
references: 11978212
references: J Gen Intern Med. 2008 Aug;23(8):1145-51
references: 18459012
references: Scand J Caring Sci. 2004 Sep;18(3):294-303
references: 15355524
references: Cephalalgia. 2011 Feb;31(3):301-15
references: 20813784
references: Headache. 2010 Apr;50(4):600-12
references: 20148982
references: Curr Genomics. 2013 Aug;14(5):300-15
references: 24403849
references: Lancet Neurol. 2006 Feb;5(2):148-157
references: 16426991
references: J Womens Health (Larchmt). 2007 Nov;16(9):1269-80
references: 18001183
references: Eur J Neurol. 1998 Nov;5(6):525-533
references: 10210887
references: Neurology. 1997 Mar;48(3 Suppl 3):S10-5
references: 9071264
references: Neurology. 2000 Sep 12;55(5):624-9
references: 10980723
references: Headache. 2010 Nov;50(10):1576-86
references: 21029083
references: Arq Neuropsiquiatr. 2000 Jun;58(2B):431-6
references: 10920404
references: Headache. 2004 Oct;44(9):856-64
references: 15447694
references: Neurology. 1994 May;44(5):837-42
references: 8190284
references: Pharmacoeconomics. 1992 Jul;2(1):67-76
references: 10146980
references: Neurology. 2005 Dec 29;65(12 Suppl 4):S50-8
references: 16385104
references: Curr Med Res Opin. 2005 Aug;21(8):1297-305
references: 16083540
references: Headache. 2001 Apr;41(4):343-50
references: 11318880
references: J Hist Neurosci. 2001 Dec;10(3):253-61
references: 11770192
references: Cephalalgia. 2013 Feb;33(3):171-81
references: 23203506
references: Med J Malaysia. 2003 Mar;58(1):79-88
references: 14556329
references: Soc Sci Med. 2005 Mar;60(6):1397-407
references: 15626533
references: J Am Board Fam Pract. 2005 Nov-Dec;18(6):563-6
references: 16322420
references: Curr Med Res Opin. 2001;17(4):298-309
references: 11922404
references: Headache. 1996 Jun;36(6):379-84
references: 8707557
references: Headache. 1997 Feb;37(2):71-8
references: 9074290
references: J Headache Pain. 2005 Dec;6(6):429-40
references: 16388337
references: Pain. 2000 Oct;88(1):41-52
references: 11098098
references: Cephalalgia. 1996 Jun;16(4):231-8; discussion 215
references: 8792034
references: Headache. 2005 May;45(5):553-60
references: 15953274
references: J Gend Specif Med. 2001;4(1):64-74
references: 11324243
references: Neurology. 1999 Sep 22;53(5):988-94
references: 10496257
references: Cephalalgia. 1992 Dec;12(6):369-74
references: 1473140
references: Headache. 2003 Apr;43(4):343-52
references: 12656705