title: A dual colorimetric-ratiometric fluorescent probe NAP-3 for selective detection and imaging of endogenous labile iron(III) pools in C. elegans.
abstract: The discovery of an iron(III)-selective ratiometric fluorescent probe to detect and visualize endogenous labile iron pools in living organisms at the molecular level has been long awaited. Herein we report the first dual colorimetric and ratiometric fluorescent probe naphtho[2,1-b][1,10]phenanthroline for selective and 'direct' visualization of labile iron(III) pools in a multicellular organism, Caenorhabditis elegans.
authors: Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, India. atul_goel@cdri.res.in.
authors: Atul
authors: A
authors: Goel
authors: Shahida
authors: S
authors: Umar
authors: Pankaj
authors: P
authors: Nag
authors: Ashutosh
authors: A
authors: Sharma
authors: Lalit
authors: L
authors: Kumar
authors: Shamsuzzama
authors: Zakir
authors: Z
authors: Hossain
authors: Jiaur R
authors: JR
authors: Gayen
authors: Aamir
authors: A
authors: Nazir
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000737:chemistry*; D003124:Colorimetry; D005290:Ferric Compounds / Q000032:analysis*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D056945:Hep G2 Cells; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure; D011789:Quantum Theory
chemical_list: D005290:Ferric Compounds; D005456:Fluorescent Dyes; D006576:Heterocyclic Compounds, 4 or More Rings; C000604647:NAP-3 compound