title: BACA: bubble chArt to compare annotations.
abstract: BACKGROUND
  DAVID is the most popular tool for interpreting large lists of gene/proteins classically produced in high-throughput experiments. However, the use of DAVID website becomes difficult when analyzing multiple gene lists, for it does not provide an adequate visualization tool to show/compare multiple enrichment results in a concise and informative manner.
  
  
  RESULTS
  We implemented a new R-based graphical tool, BACA (Bubble chArt to Compare Annotations), which uses the DAVID web service for cross-comparing enrichment analysis results derived from multiple large gene lists. BACA is implemented in R and is freely available at the CRAN repository ( http://cran.r-project.org/web/packages/BACA/ ).
  
  
  CONCLUSIONS
  The package BACA allows R users to combine multiple annotation charts into one output graph by passing DAVID website.
authors: Unit of Systems Toxicology, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250, Helsinki, Finland. vittorio.fortino@ttl.fi.|Nanosafety Centre, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250, Helsinki, Finland. vittorio.fortino@ttl.fi.
authors: Vittorio
authors: V
authors: Fortino
authors: Unit of Systems Toxicology, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250, Helsinki, Finland. harri.alenius@ttl.fi.|Nanosafety Centre, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250, Helsinki, Finland. harri.alenius@ttl.fi.
authors: Harri
authors: H
authors: Alenius
authors: Unit of Systems Toxicology, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250, Helsinki, Finland. dario.greco@ttl.fi.|Nanosafety Centre, Finnish Institute of Occupational Health (FIOH), Topeliuksenkatu 41b, 00250, Helsinki, Finland. dario.greco@ttl.fi.
authors: Dario
authors: D
authors: Greco
mesh_terms: D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D005796:Genes; D058977:Molecular Sequence Annotation; D011506:Proteins; D012984:Software
chemical_list: D011506:Proteins
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