title: Successful management of refractory immune thrombocytopenia associated with massive alveolar hemorrhage.
abstract: Immune thrombocytopenia (ITP) is an acquired immune-mediated disease characterized by persistant thrombocytopenia. Onset of the disease and the clinical course is highly variable, but the disease typically has a benign course. Patients rarely develop serious life-threatening bleeding. Herein, a case with refractory ITP and massive alveolar hemorrhage who was successfully treated with a fast and sequential approach is presented for the first time.
authors: Department of Hematology, Meram Medical School, Necmettin Erbakan University, Konya, Turkey. Electronic address: aynurugurbilgin@yahoo.com.
authors: Aynur
authors: A
authors: Uğur Bilgin
authors: Department of Hematology, Meram Medical School, Necmettin Erbakan University, Konya, Turkey.
authors: Mehmet Ali
authors: MA
authors: Karaselek
authors: Department of Hematology, Meram Medical School, Necmettin Erbakan University, Konya, Turkey.
authors: Rasim
authors: R
authors: Bilgin
mesh_terms: D000328:Adult; D001565:Benzoates / Q000008:administration & dosage; D015942:Factor VIIa / Q000627:therapeutic use; D006470:Hemorrhage / Q000150:complications* / Q000628:therapy*; D006801:Humans; D006834:Hydrazines / Q000008:administration & dosage; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008297:Male; D010976:Platelet Count; D011241:Prednisone / Q000008:administration & dosage; D011650:Pulmonary Alveoli / Q000473:pathology*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications* / Q000628:therapy*; D011720:Pyrazoles / Q000008:administration & dosage; D013902:Radiography, Thoracic; D012886:Skull / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D001565:Benzoates; D006834:Hydrazines; D007166:Immunosuppressive Agents; D011720:Pyrazoles; D014750:Vincristine; D015942:Factor VIIa; C520809:eltrombopag; D011241:Prednisone
keywords: FVIIa; Life-threatening hemorrhage; Refractory ITP