title: Caffeic acid derivatives from Bupleurum chinense.
abstract: In this study, caffeic acid (CA) and its three derivatives including 3-caffeoylquinic acid (3-CQA, neochlorogenic acid), 4-caffeoylquinic acid (4-CQA, cryptochlorogenic acid), and 5-caffeoylquinic acid (5-CQA, chlorogenic acid) were identified in Bupleurum chinense aerial parts using reverse-phase high-performance liquid chromatography (RP-HPLC) with photodiode array (PDA) detector, reference compounds and chemical reactions. Separation was performed on a C18 column using gradient elution with 4% (v/v) aqueous acetic acid and acetonitrile as mobile phase at ambient temperature. In addition, the flavonoid aglycones were characterized and quantified after acid hydrolysis of the plant material. The flavonols profile showed quercetin (0.36 g per 100 g), kaempferol (1.11 g per 100 g) and isorhamnetin (0.16 g per 100 g). Total phenolic and total flavonoid contents ranged from 7.3 to 18.7% and 0.58 to 2.72% in dry plant material, respectively.
authors: Phytochemistry Group, Barij Essence Medicinal Plants Research Center, Kashan, I.R. Iran.
authors: G
authors: G
authors: Haghi
authors: Phytochemistry Group, Barij Essence Medicinal Plants Research Center, Kashan, I.R. Iran.
authors: A
authors: A
authors: Hatami
authors: Phytochemistry Group, Barij Essence Medicinal Plants Research Center, Kashan, I.R. Iran.
authors: M
authors: M
authors: Mehran
authors: Agriculture Group, Barij Essence Medicinal Plants Research Center, Kashan, I.R. Iran.
authors: H
authors: H
authors: Hosseini
keywords: Apiaceae; Bupleurum chinense; Caffeic acid derivatives; Flavonoids; HPLC
references: Planta Med. 2003 Aug;69(8):705-9
references: 14531019
references: J Sep Sci. 2008 Oct;31(18):3190-201
references: 18763253
references: J Agric Food Chem. 2009 Jul 22;57(14):6292-7
references: 19534529
references: Planta Med. 1998 Jun;64(5):404-7
references: 9690340
references: Phytochemistry. 1993 Jul;33(5):1197-1205
references: 7764030
references: Phytochemistry. 1996 Feb;41(3):895-901
references: 8835463
references: Carbohydr Polym. 2012 Jun 20;89(2):448-52
references: 24750742
references: J Ethnopharmacol. 2005 Apr 26;98(3):329-33
references: 15814268
references: Phytother Res. 2006 Nov;20(11):1003-8
references: 16952220
references: Chem Pharm Bull (Tokyo). 2005 Dec;53(12):1613-7
references: 16327203
references: J Chromatogr A. 2011 Feb 25;1218(8):1131-8
references: 21256495
references: J Nat Prod. 1993 Feb;56(2):240-4
references: 8463796
references: Nat Prod Rep. 1997 Oct;14(5):465-75
references: 9364778
references: J Agric Food Chem. 2003 Jan 29;51(3):601-8
references: 12537429
references: Zhong Yao Cai. 2009 Mar;32(3):367-9
references: 19565712
references: J Ethnopharmacol. 2009 Jul 30;124(3):481-7
references: 19467314
references: Life Sci. 2003 Sep 19;73(18):2383-94
references: 12941440
references: J Agric Food Chem. 2010 Oct 27;58(20):10812-6
references: 20919719
references: J Pharm Pharmacol. 2011 Mar;63(3):305-21
references: 21749378
references: Am J Chin Med. 2007;35(2):341-51
references: 17436373