title: Stem cells: disease models that show and tell.
abstract: Combining gene-editing techniques with induced pluripotent stem cells is both powerful and tricky.
authors: Nature and Nature Methods v.marx@us.nature.com.
authors: Vivien
authors: V
authors: Marx
mesh_terms: D035843:Biomedical Research / Q000379:methods*; D055808:Drug Discovery / Q000379:methods; D000072669:Gene Editing / Q000379:methods*; D018390:Gene Targeting / Q000379:methods; D015316:Genetic Therapy / Q000379:methods; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology* / Q000378:metabolism*
references: J Am Coll Cardiol. 2014 Aug 5;64(5):451-9
references: 25082577
references: Cell Stem Cell. 2013 Mar 7;12 (3):354-67
references: 23472874
references: Nat Rev Genet. 2014 Sep;15(9):625-39
references: 25069490
references: Nature. 2009 Jan 15;457(7227):277-80
references: 19098894
references: Cell. 2006 Aug 25;126(4):663-76
references: 16904174
references: Dis Model Mech. 2013 Jul;6(4):896-904
references: 23751357