title: Effectiveness of a community-based multidomain cognitive intervention program in patients with Alzheimer's disease.
abstract: OBJECTIVE
  The aim of the present study was to evaluate the efficacy of a multidomain program in patients with Alzheimer's disease (AD).
  
  
  METHODS
  A total of 53 patients with probable AD participated in the present study. The participants were classified to a cognitive programming group (n = 32) and control group (n = 21). Participants in the cognitive intervention program received multidomain cognitive stimulation including art, music, recollection and horticultural therapy, each period of intervention lasting 1 h. This program was repeated five times per week over a period of 6 months at the Seongdong-gu Center for Dementia. The Mini-Mental State Examination, the Korean version of Consortium to Establish a Registry for Alzheimer's Disease, Clinical dementia rating scales, and the Korean version of the Quality of Life-Alzheimer's Disease were used to evaluate cognitive ability at baseline and after intervention. After 6 months, cognitive abilities were compared between patients actively participating in cognitive intervention and the pharmacotherapy only group.
  
  
  RESULTS
  Patients receiving cognitive intervention showed significant cognitive improvement in the word-list recognition and recall test scores versus the control. There was no change in the overall Clinical dementia rating score, but the domain of community affairs showed a significant improvement in the cognitive intervention group. Quality of Life-Alzheimer's Disease of caregivers was slightly improved in the cognitive intervention group after 6 months.
  
  
  CONCLUSIONS
  Multidomain cognitive intervention by regional dementia centers has great potential in helping to maintain cognitive function in patients with dementia, increase their social activity and reduce depression, while enhancing the quality of life of caregivers.
authors: Seongdong-Gu Community Health Center, Seongdong-Gu Regional Center for Dementia, Seoul, Korea.|Department of Neurology, Hanyang University College of Medicine, Seoul, Korea.
authors: Hee-Jin
authors: http://orcid.org/0000-0001-7880-690X
authors: HJ
authors: Kim
authors: Department of Neurology, Veterans Hospital, Seoul Medical Center, Seoul, Korea.
authors: YoungSoon
authors: Y
authors: Yang
authors: Department of Neurology, Hanyang University College of Medicine, Seoul, Korea.
authors: Jeong-Gun
authors: JG
authors: Oh
authors: Department of Neurology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
authors: Seongil
authors: S
authors: Oh
authors: Seongdong-Gu Community Health Center, Seongdong-Gu Regional Center for Dementia, Seoul, Korea.|Department of Neurology, Hanyang University College of Medicine, Seoul, Korea.
authors: Hojin
authors: H
authors: Choi
authors: Seongdong-Gu Community Health Center, Seongdong-Gu Regional Center for Dementia, Seoul, Korea.
authors: Kyoung Hee
authors: KH
authors: Kim
authors: Seongdong-Gu Community Health Center, Seongdong-Gu Regional Center for Dementia, Seoul, Korea.|Department of Neurology, Hanyang University College of Medicine, Seoul, Korea.
authors: Seung Hyun
authors: SH
authors: Kim
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000523:psychology / Q000628:therapy*; D003071:Cognition; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003156:Community Mental Health Services; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
keywords: Alzheimer's disease; cognition; community-based cognitive intervention program; quality of life