title: In Vitro Method to Quantify Dermal Absorption of Pesticide Residues.
abstract: All pesticides must go through a rigorous risk assessment process in order to show that they are safe for use.With respect to dermal risk assessment for re-entry workers, the absorption value applied to predict systemic dose from this external exposure is obtained by testing liquid forms of the pesticide in vivo and/or in vitro. However, in a real exposure scenario, the worker would be exposed to a dried residue, for which little or no absorption data are available. This study has developed a novel methodology for assessing the dermal absorption of pesticides from dried residues and aims ultimately to use this methodology to obtain more realistic absorption values for the risk assessment.
authors: James F
authors: JF
authors: Clarke
authors: Sarah F
authors: SF
authors: Cordery
authors: Neil A
authors: NA
authors: Morgan
authors: Peter K
authors: PK
authors: Knowles
authors: Richard H
authors: RH
authors: Guy
mesh_terms: D000818:Animals; D006801:Humans; D066298:In Vitro Techniques; D010573:Pesticide Residues / Q000032:analysis* / Q000378:metabolism*; D018570:Risk Assessment; D012867:Skin / Q000737:chemistry* / Q000378:metabolism*; D012869:Skin Absorption; D013552:Swine
chemical_list: D010573:Pesticide Residues