title: Large-scale imaging in small brains.
abstract: The dense connectivity in the brain means that one neuron's activity can influence many others. To observe this interconnected system comprehensively, an aspiration within neuroscience is to record from as many neurons as possible at the same time. There are two useful routes toward this goal: one is to expand the spatial extent of functional imaging techniques, and the second is to use animals with small brains. Here we review recent progress toward imaging many neurons and complete populations of identified neurons in small vertebrates and invertebrates.
authors: Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA. Electronic address: ahrensm@janelia.hhmi.org.
authors: Misha B
authors: MB
authors: Ahrens
authors: Harvard University, Department of Molecular and Cellular Biology, Cambridge, MA, USA. Electronic address: florian@mcb.harvard.edu.
authors: Florian
authors: F
authors: Engert
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D055724:Electrophysiological Phenomena / Q000502:physiology*; D059907:Functional Neuroimaging / Q000379:methods*; D023421:Models, Animal; D059906:Neuroimaging / Q000379:methods*; D009474:Neurons / Q000502:physiology*
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