title: From formamide to RNA, the path is tenuous but continuous.
abstract: Reactions of formamide (NH2COH) in the presence of catalysts of both terrestrial and meteoritic origin yield, in plausible and variegated conditions, a large panel of precursors of (pre)genetic and (pre)metabolic interest. Formamide chemistry potentially satisfies all of the steps from the very initial precursors to RNA. Water chemistry enters the scene in RNA non-enzymatic synthesis and recombination.
authors: Fondazione "Istituto Pasteur-Fondazione Cenci-Bolognetti" c/o Dipartimento di Biologia e Biotecnologie "Charles Darwin", "Sapienza" Università di Roma, P.le Aldo Moro, 5, 00185 Rome, Italy. samantapino78@libero.it.
authors: Samanta
authors: S
authors: Pino
authors: Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 61265 Brno, Czech Republic. judit@ncbr.muni.cz.|CEITEC-Central European Institute of Technology, Masaryk University, Campus Bohunice, Kamenice 5, CZ-62500 Brno, Czech Republic. judit@ncbr.muni.cz.
authors: Judit E
authors: JE
authors: Sponer
authors: Istituto di Biologia e Patologia Molecolari, CNR, P.le Aldo Moro, 5, 00185 Rome, Italy. giovanna.costanzo@uniroma1.it.
authors: Giovanna
authors: G
authors: Costanzo
authors: Dipartimento di Scienze Ecologiche e Biologiche Università della Tuscia Via San Camillo De Lellis, 01100 Viterbo, Italy. saladino@unitus.it.
authors: Raffaele
authors: R
authors: Saladino
authors: Fondazione "Istituto Pasteur-Fondazione Cenci-Bolognetti" c/o Dipartimento di Biologia e Biotecnologie "Charles Darwin", "Sapienza" Università di Roma, P.le Aldo Moro, 5, 00185 Rome, Italy. samantapino78@libero.it.
authors: Ernesto Di
authors: ED
authors: Mauro
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