title: Relationship between echocardiographic and cardiac magnetic resonance imaging-derived measures of right ventricular function in patients with chronic thromboembolic pulmonary hypertension.
abstract: BACKGROUND
  Echocardiography is widely used to evaluate right ventricular (RV) function. However, the value of echocardiographic parameters to assess RV function in patients with chronic thromboembolic pulmonary hypertension (CTEPH) is unknown. In this study, we analyzed the correlations between echocardiographic parameters and the RV ejection fraction (RVEF) as measured by cardiac magnetic resonance (CMR) imaging to systematically elucidate the role of echocardiographic parameters in the assessment of RV function in patients with CTEPH.
  
  
  METHODS
  Echocardiography was used to measure the tissue Doppler-derived tricuspid lateral annular systolic velocity (S'), fractional area change (FAC), myocardial performance index (MPI), and tricuspid annular plane systolic excursion (TAPSE). CMR was used to measure the RV end-diastolic volume (RVEDV) and end-systolic volume (RVESV), and the RVEF was calculated.
  
  
  RESULTS
  A significant positive correlation was found between S' and RVEF (r=0.689, P<0.0001) and between FAC and RVEF (r=0.423, P=0.022), a significant negative correlation was found between MPI and RVEF (r=-0.387, P=0.048), and no correlation was found between TAPSE and RVEF (r=0.451, P=0.22).
  
  
  CONCLUSIONS
  Echocardiography can be routinely used in the clinical setting to measure S', FAC, and MPI for the evaluation of right heart function in patients with CTEPH.
authors: Department of Echocardiography, Heart Center, Beijing Chao Yang Hospital, Capital Medical University, Beijing 100020, China.
authors: Yi-dan
authors: YD
authors: Li
authors: Department of Echocardiography, Heart Center, Beijing Chao Yang Hospital, Capital Medical University, Beijing 100020, China.
authors: Yi-dan
authors: YD
authors: Wang
authors: Department of Respiratory Medicine, Beijing Chao Yang Hospital, Capital Medical University, Beijing 100020, China; Beijing Key Laboratory of Respiratory and Pulmonary Circulation, Beijing Institute of Respiratory Medicine, Capital Medical University, Beijing, China.
authors: Zhen-guo
authors: ZG
authors: Zhai
authors: Department of Radiology, Beijing Chao Yang Hospital, Capital Medical University, Beijing 100020, China.
authors: Xiao-juan
authors: XJ
authors: Guo
authors: Department of Echocardiography, Heart Center, Beijing Chao Yang Hospital, Capital Medical University, Beijing 100020, China.
authors: Ya-feng
authors: YF
authors: Wu
authors: Department of Respiratory Medicine, Beijing Chao Yang Hospital, Capital Medical University, Beijing 100020, China; Beijing Key Laboratory of Respiratory and Pulmonary Circulation, Beijing Institute of Respiratory Medicine, Capital Medical University, Beijing, China.
authors: Yuan-hua
authors: YH
authors: Yang
authors: Department of Echocardiography, Heart Center, Beijing Chao Yang Hospital, Capital Medical University, Beijing 100020, China. Electronic address: chaoyanglxz@163.com.
authors: Xiu-zhang
authors: XZ
authors: Lu
mesh_terms: D002908:Chronic Disease; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013923:Thromboembolism; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging*
keywords: CMR; chronic thromboembolic pulmonary hypertension; echocardiography; right ventricular function