title: Does transcription play a role in creating a condensin binding site?
abstract: The highly conserved condensin complex is essential for the condensation and integrity of chromosomes through cell division. Published data argue that high levels of transcription contribute to specify some condensin-binding sites on chromosomes but the exact role of transcription in this process remains elusive. Here we discuss our recent data addressing the role of transcription in establishing a condensin-binding site.
authors: a CNRS, Université Lyon 01, UMR5239, LBMC; Ecole Normale Supérieure de Lyon , Lyon , France.
authors: Pascal
authors: P
authors: Bernard
authors: Vincent
authors: V
authors: Vanoosthuyse
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism*; D001665:Binding Sites; D002877:Chromosomes, Human / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism*; D006801:Humans; D046912:Multiprotein Complexes / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D004268:DNA-Binding Proteins; D046912:Multiprotein Complexes; D029701:Saccharomyces cerevisiae Proteins; C108312:condensin complexes; D000251:Adenosine Triphosphatases
keywords: CPF; R-Loops; Sen1; condensin; topological stress; transcription
references: Mol Cell Biol. 1997 Oct;17(10):5791-802
references: 9315637
references: J Cell Biol. 1963 Nov;19:267-77
references: 14086755
references: Nat Cell Biol. 2006 Oct;8(10):1133-42
references: 16998479
references: Genes Dev. 2008 Aug 15;22(16):2215-27
references: 18708580
references: Mol Cell. 2009 Feb 27;33(4):450-61
references: 19250906
references: Nature. 2009 Mar 12;458(7235):219-22
references: 19158678
references: Cell. 2009 May 15;137(4):685-96
references: 19450516
references: Mol Biol Cell. 2010 Jan 15;21(2):254-65
references: 19910488
references: Nucleic Acids Res. 2010 Jun;38(10):3454-65
references: 20139420
references: Mol Cell. 2011 Jan 7;41(1):21-32
references: 21211720
references: Nat Cell Biol. 2011 Dec;13(12):1450-6
references: 22020438
references: Mol Cell Proteomics. 2004 Feb;3(2):125-32
references: 14617822
references: Mol Cell. 2012 Mar 30;45(6):814-25
references: 22387027
references: Open Biol. 2011 Dec;1(4):110023
references: 22645654
references: Chromosoma. 2013 Jun;122(3):175-90
references: 23546018
references: Elife. 2013;2:e00808
references: 23795297
references: Nat Struct Mol Biol. 2013 Jul;20(7):884-91
references: 23748379
references: Nat Commun. 2013;4:2537
references: 24088984
references: BMC Genomics. 2013;14:813
references: 24256300
references: Cancer Res. 2014 Jan 15;74(2):420-5
references: 24408924
references: Cell Rep. 2014 Mar 13;6(5):892-905
references: 24565511
references: PLoS Genet. 2014 Apr;10(4):e1004288
references: 24743342
references: Nat Struct Mol Biol. 2014 Jun;21(6):560-8
references: 24837193
references: PLoS Genet. 2014 Jun;10(6):e1004415
references: 24945319
references: Genes Dev. 2014 Jul 1;28(13):1384-96
references: 24990962
references: PLoS Genet. 2014 Oct;10(10):e1004716
references: 25357144
references: PLoS Genet. 2014 Nov;10(11):e1004794
references: 25392932
references: Trends Cell Biol. 2014 Dec;24(12):727-33
references: 25092191
references: Biochemistry. 1999 Nov 2;38(44):14697-710
references: 10545196
references: Genes Dev. 2012 Jan 15;26(2):163-75
references: 22279048