title: Association between maternal and fetal factors and quality of cord blood as a source of stem cells.
abstract: OBJECTIVE
  To comparatively analyze maternal and fetal factors and quality markers of blood samples in a public umbilical cord blood bank.
  
  
  METHODS
  This is a cross-sectional descriptive study that revisited 458 records of donations from September 2009 to March 2013 at the Hemocentro de Santa Catarina. The means of markers were used to define cutoff points for the quality of cord blood.
  
  
  RESULTS
  Most donations came from women with ages between 18 and 29 years (62.8%), gestational age≥40 weeks (55.2%), vaginal delivery (51.3%), primiparous (41.4%), and with male newborns (54.4%) weighing between 3000 and 3499g (41.8%). The volume of the donations ranged from 71.6 to 275.2mL, the total nucleated cell count ranged from 4.77×10(8) to 31.0×10(8) cells and CD34(+) cells ranged from 0.05 to 1.23%. There were statistically significant differences in the volume with respect to gestation age>38 weeks (p-value=0.001), cesarean section (p-value<0.001) and birth weight>3500g (p-value<0.001). The total nucleated cell count was positively affected by cesarean section (p-value=0.022) and birth weight>3500g (p-value<0.001). There was no statistically significant difference between the variables and the percentage of CD34(+) cells.
  
  
  CONCLUSIONS
  Delivery route and birth weight influence the volume of cord blood and the total nucleated cell count. Gestational age influences only the volume of cord blood.
authors: Universidade do Sul de Santa Catarina (UNISUL), Florianópolis, SC, Brazil. Electronic address: rodrigo.dias.nunes@hotmail.com.
authors: Rodrigo Dias
authors: RD
authors: Nunes
authors: Universidade do Sul de Santa Catarina (UNISUL), Florianópolis, SC, Brazil.
authors: Flávia Maria
authors: FM
authors: Zandavalli
keywords: Blood banks; Cord blood stem cell transplantation; Fetal blood; Stem cells; Transplantation
references: Bone Marrow Transplant. 2001 Jan;27(1):7-14
references: 11244432
references: Acta Obstet Gynecol Scand. 2000 Oct;79(10):830-3
references: 11304964
references: Transfusion. 2002 Feb;42(2):210-5
references: 11896337
references: Transfusion. 2004 Feb;44(2):262-7
references: 14962318
references: Transfusion. 2005 Feb;45(2):189-94
references: 15660826
references: J Obstet Gynaecol Can. 2005 Mar;27(3):263-90
references: 15943003
references: Transplant Proc. 2006 May;38(4):1174-6
references: 16757298
references: Pediatr Transplant. 2008 Dec;12(8):868-73
references: 18643913
references: Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010 Dec;18(6):1535-41
references: 21176366
references: Angiogenesis. 2011 Sep;14(3):381-92
references: 21720855
references: Transfus Apher Sci. 2012 Feb;46(1):7-13
references: 22192902
references: Transfus Apher Sci. 2012 Feb;46(1):39-45
references: 22206793
references: Transfusion. 2012 Oct;52(10):2234-42
references: 22321210
references: Akush Ginekol (Sofiia). 2012;51(2):11-6
references: 23234008
references: Transfus Apher Sci. 2013 Apr;48(2):247-52
references: 23415410
references: Transfusion. 2014 Mar;54(3):545-9
references: 23869580
references: Einstein (Sao Paulo). 2011 Jun;9(2):207-11
references: 26760817