title: Serologic screening of celiac disease in adolescents.
abstract: OBJECTIVE
  This study aimed to identify the seroprevalence of celiac disease in adolescents from public schools in the city of Salvador, Bahia.
  
  
  METHODS
  This was a cross-sectional study with probabilistic sample of 1,213 adolescents, aged 11 to 17 years old, of both genders. The body mass index was used to determine the participants' nutritional status based on the percentiles for age and gender recommended by the World Health Organization. Measurement of the anti-human transglutaminase immunoglobulin A (anti-tTG-IgA) antibody was established as the specific screening test for celiac disease, which involved an enzyme-linked immunosorbent assay (ELISA). Descriptive analysis was performed using proportions and means (standard deviation).
  
  
  RESULTS
  The female gender prevailed in the sample, and most of the participants had normal weights. The anti-tTG-IgA antibody was positive in 6/1,213 (0.49%) adolescents.
  
  
  CONCLUSIONS
  The seroprevalence of celiac disease was 0.49% in the investigated adolescents. Further studies are necessary to establish the prevalence of celiac disease in this age range.
authors: Escola de Nutrição, Universidade Federal da Bahia, Salvador, BA, Brasil.
authors: Maria Ester Pereira
authors: ME
authors: da Conceição-Machado
authors: Escola de Nutrição, Universidade Federal da Bahia, Salvador, BA, Brasil.
authors: Mônica Leila Portela
authors: ML
authors: Santana
authors: Escola de Nutrição, Universidade Federal da Bahia, Salvador, BA, Brasil.
authors: Rita de Cássia Ribeiro
authors: Rde C
authors: Silva
authors: Universidade Federal da Bahia, Salvador, BA, Brasil.
authors: Luciana Rodrigues
authors: LR
authors: Silva
authors: Centro de Ciências da Saúde, Universidade Federal do Recôncavo da Bahia, Santo Antônio de Jesus, BA, Brasil.
authors: Elizabete Jesus
authors: EJ
authors: Pinto
authors: Complexo Hospitalar Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, BA, Brasil.
authors: Ricardo David
authors: RD
authors: Couto
authors: Instituto de Matemática, Universidade Federal da Bahia, Salvador, BA, Brasil.
authors: Lia Terezinha Lana Pimenta
authors: LT
authors: Moraes
authors: Escola de Nutrição, Universidade Federal da Bahia, Salvador, BA, Brasil.
authors: Ana Marlúcia Oliveira
authors: AM
authors: Assis
mesh_terms: D000293:Adolescent; D000888:Antibodies, Anti-Idiotypic / Q000276:immunology; D002446:Celiac Disease / Q000097:blood* / Q000175:diagnosis*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D011503:Transglutaminases / Q000276:immunology
chemical_list: D000888:Antibodies, Anti-Idiotypic; C049937:anti-IgA; D011503:Transglutaminases