title: Common temporal identity factors regulate neuronal diversity in fly ventral nerve cord and mouse retina.
abstract: Temporal sequences of transcription factors (tTFs) in Drosophila neural progenitors generate neuronal diversity. Mattar et al. (2015) identify Casz1/Castor as a late temporal identity factor in mouse retinal progenitors that is regulated by the early factor Ikzf1/Hunchback, thus generalizing the notion of tTFs.
authors: Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA.
authors: Nikolaos
authors: N
authors: Konstantinides
authors: Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA.
authors: Anthony M
authors: AM
authors: Rossi
authors: Department of Biology, New York University, 1009 Silver Center, 100 Washington Square East, New York, NY 10003, USA. Electronic address: cd38@nyu.edu.
authors: Claude
authors: C
authors: Desplan
mesh_terms: D000818:Animals; D004268:DNA-Binding Proteins / Q000096:biosynthesis*; D029721:Drosophila Proteins / Q000096:biosynthesis*; D005260:Female; D058953:Neural Stem Cells / Q000378:metabolism*; D011247:Pregnancy; D055351:Retinal Neurons / Q000378:metabolism*; D014157:Transcription Factors / Q000096:biosynthesis*
chemical_list: C511127:CASZ1 protein, human; D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D014157:Transcription Factors
references: Dev Biol. 2000 Oct 1;226(1):34-44
references: 10993672
references: Neuron. 2008 Oct 9;60(1):26-39
references: 18940586
references: Nature. 2003 Oct 9;425(6958):624-8
references: 14534589
references: Anat Rec. 1985 Jun;212(2):199-205
references: 3842042
references: Cell. 1999 Jun 11;97(6):703-16
references: 10380923
references: Cell. 2001 Aug 24;106(4):511-21
references: 11525736
references: Development. 2010 May;137(9):1421-30
references: 20335359
references: Development. 2011 Jan;138(2):227-35
references: 21148186
references: Neuron. 2012 Sep 6;75(5):786-98
references: 22958820
references: Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E716-25
references: 23382203
references: Nature. 2013 Jun 27;498(7455):456-62
references: 23783517
references: Nature. 2013 Jun 27;498(7455):449-55
references: 23783519
references: Nat Rev Neurosci. 2014 Sep;15(9):615-27
references: 25096185
references: Cell. 2014 Aug 28;158(5):1173-86
references: 25171415
references: Neuron. 2015 Feb 4;85(3):497-504
references: 25654255