title: Functional Connectivity in Patients With Sensorineural Hearing Loss Using Resting-State MRI.
abstract: OBJECTIVE
  This study was undertaken to evaluate whole-brain functional connectivity changes related to auditory cortex in patients with left-sided sensorineural hearing loss (SNHL) using resting-state functional connectivity magnetic resonance imaging.
  
  
  METHODS
  Imaging was performed in 19 patients with left-sided SNHL and 35 individuals in the control group without SNHL. Data were collected and analyzed to map functional connectivity using the left/right primary auditory cortex as the region of interest to identify global differences between patients with SNHL and the control group.
  
  
  RESULTS
  In comparison to the control group, the SNHL group was found to have significant functional connectivity changes in the auditory system, recognition network, visual cortex, and language network.
  
  
  CONCLUSIONS
  These findings suggest that functional brain alterations in unilateral SNHL patients may indicate reorganizations that occur in response to auditory deficits.
authors: Bin
authors: B
authors: Liu
authors: Yuan
authors: Y
authors: Feng
authors: Ming
authors: M
authors: Yang
authors: Jing-ya
authors: JY
authors: Chen
authors: Jing
authors: J
authors: Li
authors: Zhi-chun
authors: ZC
authors: Huang
authors: Ling-ling
authors: LL
authors: Zhang
mesh_terms: D000328:Adult; D001303:Auditory Cortex / Q000000981:diagnostic imaging / Q000503:physiopathology; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016022:Case-Control Studies; D005260:Female; D059907:Functional Neuroimaging; D006319:Hearing Loss, Sensorineural / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009434:Neural Pathways / Q000000981:diagnostic imaging / Q000503:physiopathology