title: New therapeutics to modulate mitochondrial dynamics and mitophagy in cardiac diseases.
abstract: The processes that control the number and shape of the mitochondria (mitochondrial dynamics) and the removal of damaged mitochondria (mitophagy) have been the subject of intense research. Recent work indicates that these processes may contribute to the pathology associated with cardiac diseases. This review describes some of the key proteins that regulate these processes and their potential as therapeutic targets for cardiac diseases.
authors: Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
authors: Marie-Hélène
authors: MH
authors: Disatnik
authors: Sunhee
authors: S
authors: Hwang
authors: Julio C B
authors: JC
authors: Ferreira
authors: Daria
authors: D
authors: Mochly-Rosen
mesh_terms: D000818:Animals; D002316:Cardiotonic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006331:Heart Diseases / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008929:Mitochondria, Heart / Q000502:physiology; D063154:Mitochondrial Dynamics; D063306:Mitophagy
chemical_list: D002316:Cardiotonic Agents
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