title: An improved fiber tracking algorithm based on fiber assignment using the continuous tracking algorithm and two-tensor model.
abstract: This study tested an improved fiber tracking algorithm, which was based on fiber assignment using a continuous tracking algorithm and a two-tensor model. Different models and tracking decisions were used by judging the type of estimation of each voxel. This method should solve the cross-track problem. This study included eight healthy subjects, two axonal injury patients and seven demyelinating disease patients. This new algorithm clearly exhibited a difference in nerve fiber direction between axonal injury and demyelinating disease patients and healthy control subjects. Compared with fiber assignment with a continuous tracking algorithm, our novel method can track more and longer nerve fibers, and also can solve the fiber crossing problem.
authors: Department of Radiology, Xiamen Second Hospital, Teaching Hospital of Fujian Medical University, Xiamen 361021, Fujian Province, China.
authors: Liuhong
authors: L
authors: Zhu
authors: Department of Radiology, Xiamen Second Hospital, Teaching Hospital of Fujian Medical University, Xiamen 361021, Fujian Province, China.
authors: Gang
authors: G
authors: Guo
keywords: axonal injury; demyelinating disease; diffusion tensor imaging; fiber assignment by continuous tracking; fiber tracking; neural regeneration; two-tensor model
references: Neuroimage. 2009 Aug;47 Suppl 2:T98-106
references: 18657622
references: Neurology. 2009 Nov 24;73(21):1718-9
references: 19846831
references: Neuroimage. 2005 Aug 15;27(2):357-67
references: 15921931
references: Magn Reson Imaging Clin N Am. 2009 May;17(2):205-14
references: 19406354
references: Proc SPIE Int Soc Opt Eng. 2010;7623:76231H
references: 20396591
references: Neuroradiology. 2004 May;46(5):339-50
references: 15103435
references: NMR Biomed. 2002 Nov-Dec;15(7-8):468-80
references: 12489096
references: Nat Rev Neurosci. 2003 Jun;4(6):469-80
references: 12778119
references: Neurosurgery. 2005;56(1):130-7; discussion 138
references: 15617595
references: Magn Reson Med. 2000 Oct;44(4):625-32
references: 11025519
references: J Magn Reson Imaging. 2001 Apr;13(4):534-46
references: 11276097
references: AJR Am J Roentgenol. 2002 Jan;178(1):3-16
references: 11756078
references: AJNR Am J Neuroradiol. 2008 Apr;29(4):632-41
references: 18339720
references: Radiology. 2007 Nov;245(2):367-84
references: 17940300
references: IEEE Trans Vis Comput Graph. 2009 Nov-Dec;15(6):1441-8
references: 19834219
references: Surg Neurol. 2007 Sep;68(3):285-91; discussion 291
references: 17719968
references: Hum Brain Mapp. 2003 Apr;18(4):306-21
references: 12632468
references: Ann Neurol. 1999 Feb;45(2):265-9
references: 9989633
references: Biophys J. 1994 Jan;66(1):259-67
references: 8130344