title: [Value of whole-body MRI in vertebral fractures].
abstract: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare autoinflammatory disease in children. Pathological vertebral fracture may be the first symptom revealing this disease. We describe the case of a 14-year-old boy, with no significant past medical history, who had a sudden dorsal pain after carrying a friend on his back. Plain radiographs and MRI showed fractures of the superior endplate of T5 and T6 associated with a mild degree of kyphosis. MRI allowed ruling out discitis. The diagnostic hypotheses raised were cancer (lymphoma, leukemia), Langerhans cell histiocytosis, osteogenesis imperfecta, and CRMO. A whole-body MRI (wbMRI) was performed and disclosed several clinically silent signal abnormalities in key sites of CRMO (pelvic bone and tibial metaphyses). We point out that CRMO should be systematically added to the list of possible diseases in case of vertebral fracture. In this perspective, wbMRI is a major noninvasive tool to assess the diagnosis of CRMO, and allows avoiding a bone biopsy in most cases.
authors: Service de pédiatrie générale, rhumatologie pédiatrique, centre national de référence des maladies auto-inflammatoires, CEREMAI, CHU Bicêtre, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France. Electronic address: caroline.galeotti@gmail.com.
authors: C
authors: C
authors: Galeotti
authors: Service de pédiatrie générale, rhumatologie pédiatrique, centre national de référence des maladies auto-inflammatoires, CEREMAI, CHU Bicêtre, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France.
authors: S
authors: S
authors: Tatencloux
authors: Service de radiologie pédiatrique, CHU Bicêtre, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France; Faculté de médecine Le Kremlin-Bicêtre, université Paris Sud, 94270 Le Kremlin-Bicêtre, France.
authors: C
authors: C
authors: Adamsbaum
authors: Service de pédiatrie générale, rhumatologie pédiatrique, centre national de référence des maladies auto-inflammatoires, CEREMAI, CHU Bicêtre, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France; Faculté de médecine Le Kremlin-Bicêtre, université Paris Sud, 94270 Le Kremlin-Bicêtre, France.
authors: I
authors: I
authors: Koné-Paut
mesh_terms: D000293:Adolescent; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010019:Osteomyelitis / Q000150:complications; D016103:Spinal Fractures / Q000175:diagnosis* / Q000209:etiology; D013904:Thoracic Vertebrae / Q000293:injuries*; D051598:Whole Body Imaging / Q000379:methods