title: Highly selective Pd-catalyzed intermolecular fluorosulfonylation of styrenes.
abstract: A novel Pd-catalyzed intermolecular regio- and diastereoselective fluorosulfonylation of styrenes has been developed under mild conditions. This reaction exhibits a wide range of functional-group tolerance in styrenes and arylsulfinic acids to afford various β-fluoro sulfones. Preliminary mechanistic study reveals an unusual mechanism, in which a high-valent L2Pd(III)F species side-selectively reacts with a benzylic carbon radical to deliver a C-F bond. This pathway is distinct from a previously reported radical fluorination reaction.
authors: State Key Laboratory of Organometallic Chemistry and ‡National Center for Organic Mass Spectrometry in Shanghai, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai, China , 200032.
authors: Zheliang
authors: Z
authors: Yuan
authors: Hao-Yang
authors: HY
authors: Wang
authors: Xin
authors: X
authors: Mu
authors: Pinhong
authors: P
authors: Chen
authors: Yin-Long
authors: YL
authors: Guo
authors: Guosheng
authors: G
authors: Liu
mesh_terms: D002384:Catalysis; D054879:Halogenation; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D013343:Styrenes / Q000737:chemistry*; D013450:Sulfones / Q000737:chemistry*
chemical_list: D013343:Styrenes; D013450:Sulfones; D010165:Palladium