title: Food derived microRNAs.
abstract: Foods provide fats, carbohydrates, and proteins as well as vitamins, minerals and trace elements. These dietary factors may influence cellular processes by regulating endogenous microRNA expression. MicroRNAs are non-coding regulatory molecules which affect gene expression at the post transcriptional level. It has been shown that plant and animal derived foods also contain microRNA. Yet, it is unclear if and to what extent plant and animal food derived microRNAs are absorbed by mammals. Thus, future studies need to better address absorption, tissue distribution and function of dietary plant and animal derived microRNAs in the context of human health and disease.
authors: Institute of Human Nutrition and Food Science, Christian-Albrechts-University, Hermann-Rodewald-Str. 6, 24118 Kiel, Germany. wagner@molecularnutrition.uni-kiel.de.
authors: Anika E
authors: AE
authors: Wagner
authors: Stefanie
authors: S
authors: Piegholdt
authors: Martin
authors: M
authors: Ferraro
authors: Kathrin
authors: K
authors: Pallauf
authors: Gerald
authors: G
authors: Rimbach
mesh_terms: D000818:Animals; D004032:Diet / Q000009:adverse effects; D005504:Food Analysis; D005786:Gene Expression Regulation; D006801:Humans; D007408:Intestinal Absorption; D035683:MicroRNAs / Q000008:administration & dosage / Q000009:adverse effects / Q000032:analysis / Q000378:metabolism*; D008954:Models, Biological; D009753:Nutritive Value; D034622:RNA Interference; D018749:RNA, Plant / Q000008:administration & dosage / Q000009:adverse effects / Q000032:analysis / Q000378:metabolism; D034743:RNA-Induced Silencing Complex / Q000378:metabolism
chemical_list: D035683:MicroRNAs; D018749:RNA, Plant; D034743:RNA-Induced Silencing Complex