title: Atrial fibrillation in outpatients with stable coronary artery disease: results from the multicenter RECENT study.
abstract: BACKGROUND
  Atrial fibrillation (AF) frequently coexists with other cardiovascular diseases.
  
  
  OBJECTIVE
  The aim of this study was to assess the prevalence of AF in outpatients with stable coronary artery disease (CAD) and to determine clinical and laboratory parameters associated with the higher prevalence of this arrhythmia. In addition, we compared the indications for antithrombotic treatment using the older CHADS₂ and the currently used CHA₂DS₂-VASc scores.
  
  
  METHODS
  We studied the clinical data of 2578 Polish patients with stable CAD participating in the multicenter RECENT study (age, 65 ±10 years; men, 55%; Canadian Cardiovascular Society class I/II/III+IV, 38%/48%/14%).
  
  
  RESULTS
  AF was present in 19% of patients with CAD. Advanced age, longer history of CAD, and concomitant heart failure were independently associated with the higher prevalence of AF (all P <0.05). Among patients with CAD and AF, 73% of the patients required antithrombotic treatment according to the CHADS₂ score (≥2), and 94%-according to the CHA₂DS₂-VASc score (≥2). A CHA₂DS₂-VASc score of 2 or higher was found in 47% of the patients with a CHADS₂ score of 0 and 85% of those with a CHADS2 score of 1. Twenty-one percent of patients with CAD and AF did not have unequivocal indications for antithrombotic treatment according to the CHADS₂ score (0-1), while they had strong indications for such treatment on the basis of the CHA₂DS₂-VASc score (≥2).
  
  
  CONCLUSIONS
  AF affects every fifth ambulatory patient with CAD. According to the CHA₂DS₂-VASc score, almost all patients with CAD and AF require antithrombotic treatment, which may complicate coronary revascularization and related antiplatelet treatment.
authors: Anna
authors: A
authors: Zielonka
authors: Michał
authors: M
authors: Tkaczyszyn
authors: Maciej
authors: M
authors: Mende
authors: Wojciech
authors: W
authors: Nowak
authors: Konrad
authors: K
authors: Rekucki
authors: Przemysław
authors: P
authors: Soczomski
authors: Michał
authors: M
authors: Zieliński
authors: Robert
authors: R
authors: Pociupany
authors: Arleta
authors: A
authors: Wilkins
authors: Waldemar
authors: W
authors: Banasiak
authors: Piotr
authors: P
authors: Ponikowski
authors: Ewa A
authors: EA
authors: Jankowska
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D015897:Comorbidity; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index
chemical_list: D005343:Fibrinolytic Agents