title: Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): the TRIPOD Statement.
abstract: BACKGROUND
  Prediction models are developed to aid healthcare providers in estimating the probability or risk that a specific disease or condition is present (diagnostic models) or that a specific event will occur in the future (prognostic models), to inform their decision-making. However, the overwhelming evidence shows that the quality of reporting of prediction model studies is poor. Only with full and clear reporting of information on all aspects of a prediction model can risk of bias and potential usefulness of prediction models be adequately assessed. The Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) Initiative developed a set of recommendations for the reporting of studies developing, validating or updating a prediction model, whether for diagnostic or prognostic purposes. This article describes how the TRIPOD Statement was developed.
  
  
  METHODS
  An extensive list of items based on a review of the literature was created, which was reduced after a web-based survey and revised during a 3-day meeting in June 2011 with methodologists, healthcare professionals and journal editors. The list was refined during several meetings of the steering group and in e-mail discussions with the wider group of TRIPOD contributors.
  
  
  RESULTS
  The resulting TRIPOD Statement is a checklist of 22 items, deemed essential for transparent reporting of a prediction model study.
  
  
  CONCLUSIONS
  The TRIPOD Statement aims to improve the transparency of the reporting of a prediction model study regardless of the study methods used. The TRIPOD Statement is best used in conjunction with the TRIPOD explanation and elaboration document. A complete checklist is available at http://www.tripod-statement.org.
authors: Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK.
authors: G S
authors: GS
authors: Collins
authors: J B
authors: JB
authors: Reitsma
authors: D G
authors: DG
authors: Altman
authors: K G M
authors: KG
authors: Moons
mesh_terms: D032921:Consensus; D003661:Decision Support Techniques; D003933:Diagnosis; D015233:Models, Statistical; D017410:Practice Guidelines as Topic; D011379:Prognosis; D011643:Publishing / Q000592:standards; D012107:Research Design / Q000592:standards; D018570:Risk Assessment; D054928:Validation Studies as Topic