title: Progress in asymmetric biomimetic transamination of carbonyl compounds.
abstract: Transamination of α-keto acids with transaminases and pyridoxamine phosphate is an important process to form optically active α-amino acids in biological systems. Various biomimetic transamination systems have been developed for carbonyl compounds including α-keto acid derivatives, fluoroalkyl ketones, and unactivated ketones with chiral vitamin B6 analogues, artificial transaminase mimics, chiral nitrogen sources, and chiral catalysts. This review provides a brief summary of this area.
authors: Beijing National Laboratory of Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors: Ying
authors: Y
authors: Xie
authors: Hongjie
authors: H
authors: Pan
authors: Mao
authors: M
authors: Liu
authors: Xiao
authors: X
authors: Xiao
authors: Yian
authors: Y
authors: Shi
mesh_terms: D000586:Amination; D000596:Amino Acids / Q000737:chemistry; D032701:Biomimetics; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D000637:Transaminases / Q000737:chemistry; D025101:Vitamin B 6 / Q000031:analogs & derivatives
chemical_list: D000596:Amino Acids; D007659:Ketones; D025101:Vitamin B 6; D000637:Transaminases