title: Photoactivatable aggregation-induced emission fluorophores with multiple-color fluorescence and wavelength-selective activation.
abstract: Photoactivatable (caged) fluorophores are widely used in chemistry, materials, and biology. However, the development of such molecules exhibiting photoactivable solid-state fluorescence is still challenging due to the aggregation-caused quenching (ACQ) effect of most fluorophores in their aggregate or solid states. In this work, we developed caged salicylaldehyde hydrazone derivatives, which are of aggregation-induced emission (AIE) characteristics upon light irradiation, as efficient photoactivatable solid-state fluorophores. These compounds displayed multiple-color emissions and ratiometric (photochromic) fluorescence switches upon wavelength-selective photoactivation, and were successfully applied for photopatterning and photoactivatable cell imaging in a multiple-color and stepwise manner.
authors: Department of Chemistry, Beijing Key Laboratory for Analytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Tsinghua University, Beijing 100084 (PR China).
authors: Lu
authors: L
authors: Peng
authors: Yue
authors: Y
authors: Zheng
authors: Xiaoyan
authors: X
authors: Wang
authors: Aijun
authors: A
authors: Tong
authors: Yu
authors: Y
authors: Xiang
mesh_terms: D061885:Chromophore-Assisted Light Inactivation / Q000379:methods*; D005453:Fluorescence; D015394:Molecular Structure; D055668:Photochemical Processes
keywords: aggregation-induced emission; cell imaging; fluorescence; hydrazones; photoactivatable fluorophores