title: Cutaneous bacillary angiomatosis due to Bartonella quintana in a renal transplant recipient.
abstract: Bacillary angiomatosis (BA) is a disorder of neovascular proliferation involving skin and other organs of immunosuppressed patients caused by Bartonella species. BA has been recognized in both immunocompetent and immunodeficient patients, mostly in human immunodeficiency virus (HIV)-infected persons, much more rare in those with other immunodeficiencies, including organ transplantation. Diagnosis is based on serologic analysis, culture and molecular biology [detection of Bartonella species deoxyribonucleic acid (DNA) in tissue biopsy extracts by real-time polymerase chain reaction (PCR)]. All immunosuppressed patients with BA should be treated with antibiotics because of potentially life-threatening course of the disease. We report the first case of cutaneous bacillary angiomatosis due to Bartonella quintana in renal transplant recipient. This presentation demonstrates that BA should be considered a differential diagnosis in immunocompromised patients presenting with fever and cutaneous angioma-like lesions.
authors: Department of Internal Medicine III - Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic.
authors: Jiri
authors: J
authors: Orsag
authors: Patrik
authors: P
authors: Flodr
authors: Oto
authors: O
authors: Melter
authors: Jan
authors: J
authors: Tkadlec
authors: Jan
authors: J
authors: Sternbersky
authors: Miroslav
authors: M
authors: Hruby
authors: Anna
authors: A
authors: Klicova
authors: Kamil
authors: K
authors: Zamboch
authors: Karel
authors: K
authors: Krejci
authors: Josef
authors: J
authors: Zadrazil
mesh_terms: D000293:Adolescent; D000328:Adult; D016917:Angiomatosis, Bacillary / Q000276:immunology* / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D018413:Bartonella quintana; D001706:Biopsy; D002648:Child; D004247:DNA / Q000737:chemistry; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000737:chemistry; D007676:Kidney Failure, Chronic / Q000150:complications / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D060888:Real-Time Polymerase Chain Reaction; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents; D004247:DNA
keywords: Bartonella quintana; bacillary angiomatosis; immunosuppression; renal transplantation