title: A new aromatic glucoside from stem bark of Illicium difengpi K.I.B. et K.I.M.
abstract: A new aromatic glucoside, namely 4-methoxyphenyl-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside (1), together with six known aromatic glucosides (2-7) were isolated from the stem bark of Illicium difengpi. The structures of these compounds were established by spectroscopic methods. The isolated aromatic glucosides were tested for anti-inflammatory activity. Compounds 1, 3 and 6 showed significant inhibitory effect on nuclear factor kappa B (NF-κB) in RAW 264.7 macrophages induced by lipopolysaccharide.
authors: a Department of Pharmacy and Pharmacology , First Affiliated Hospital of PLA General Hospital , Beijing 100048 , P.R. China.
authors: Chuntong
authors: C
authors: Li
authors: Zhijun
authors: Z
authors: Wu
authors: Wansheng
authors: W
authors: Chen
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D029523:Illicium / Q000737:chemistry*; D051379:Mice; D015394:Molecular Structure; D016328:NF-kappa B / Q000378:metabolism; D024301:Plant Bark / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry; D000067996:RAW 264.7 Cells / Q000187:drug effects
chemical_list: D000893:Anti-Inflammatory Agents; D005960:Glucosides; D016328:NF-kappa B; D010936:Plant Extracts
keywords: Illicium difengpi; anti-inflammatory; aromatic glucoside