title: [The diagnosis and treatment of arsenic trioxide induced necrosis of jaws: report of 10 consecutive cases].
abstract: OBJECTIVE
  To discuss the diagnosis and treatment of necrosis of jaws caused by leakage of arsenite trioxide, and to emphasize the consequences of its use.
  
  
  METHODS
  Ten cases of arsenical necrosis of the jaws from Jan, 2009 to Jun, 2014 treated in our department were collected and analyzed, with emphasis on the key points of diagnosis and treatment.
  
  
  RESULTS
  Diagnosis was based on medical history, clinical examinations, X-ray findings, and preoperative or intraoperative cone-beam CT (CBCT) scans. Nine patients were cured with primary operation, one patient was cured by secondary extended surgery.
  
  
  CONCLUSIONS
  Because of the high toxicity, there is no justification for the use of arsenite trioxide in clinic.
authors: Department of Oral and Maxillofacial Surgery, The Affiliated Stomatological Hospital of Fujian Medical University. Fuzhou 350002, Fujian Province, China.E-mail:1713746079@qq.com.
authors: Ye
authors: Y
authors: Wu
authors: Li-song
authors: LS
authors: Lin
authors: Gang
authors: G
authors: Niu
authors: Fu-ping
authors: FP
authors: Xie
mesh_terms: D000368:Aged; D000077237:Arsenic Trioxide; D001152:Arsenicals; D018053:Arsenites; D054893:Cone-Beam Computed Tomography; D006801:Humans; D007571:Jaw Diseases; D010020:Osteonecrosis; D010087:Oxides
chemical_list: D001152:Arsenicals; D018053:Arsenites; D010087:Oxides; C015001:arsenite; D000077237:Arsenic Trioxide