title: Patient-specific implants for lateral unicompartmental knee arthroplasty.
abstract: OBJECTIVE
  The lateral compartment of the knee is biomechanically and anatomically different from the medial compartment. Most commercially available unicompartmental implants are not designed specifically for the lateral compartment. Patient-specific custom-made unicompartmental knee arthroplasty (UKA) are designed to provide optimal fit on both femoral and tibial surfaces. This study aimed to determine if the use of patient-specific lateral unicompartmental implants provide better bone coverage than standard, off-the-shelf commercially available unicompartmental implants in lateral unicompartmental knee arthroplasties. As a secondary question, we wished to determine if patient-specific unicompartmental implants provide good clinical outcomes in surgical treatment of lateral unicompartmental osteoarthritis.
  
  
  METHODS
  We prospectively evaluated 33 patients who underwent lateral unicompartmental arthroplasty using patient-specific implants and instrumentation with a minimum of 24 months of follow-up. We analysed bone coverage observed in plain radiographs in 33 patient-specific lateral unicompartmental arthroplasties and compared to 20 lateral unicompartmental arthroplasties performed with commercially-available, standard off-the-shelf unicondylar implants.
  
  
  RESULTS
  The mean tibial implant lateral coverage mismatch in the patient-specific implant group was 1.0 mm (S.D. 1.2, range 0-5.7 mm ) versus 3.3 mm (S.D. 2.43, range 0.4-7.8 mm) in the conventional implant group (p < 0.01). In the patient specific cohort, pre-operative limb alignment was 3.3 (valgus) and post-operative limb alignment was -0.9 (varus). The Knee Society score improved from 48 (S.D. 16.2) to 95 (S.D. 7.6). Survivorship in the patient-specific implant group was 97% at an average follow up of 37 months, versus 85% at a follow-up period of 32 months for the standard implant group.
  
  
  CONCLUSIONS
  Patient-specific lateral unicompartmental knee replacements demonstrated better tibial coverage and provide excellent short-term clinical and radiological results as compared to a standard lateral UKA.
authors: Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, demange@usp.br.
authors: Marco K
authors: MK
authors: Demange
authors: Arvind
authors: A
authors: Von Keudell
authors: Christian
authors: C
authors: Probst
authors: Hiroshi
authors: H
authors: Yoshioka
authors: Andreas H
authors: AH
authors: Gomoll
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D005260:Female; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery; D011184:Postoperative Period; D011446:Prospective Studies; D011474:Prosthesis Design; D017755:Prosthesis Fitting; D016896:Treatment Outcome
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