title: Aggregation-induced structure transition of protein-stabilized zinc/copper nanoclusters for amplified chemiluminescence.
abstract: A stable, water-soluble fluorescent Zn/Cu nanocluster (NC) capped with a model protein, bovine serum albumin (BSA), was synthesized and applied to the reaction of hydrogen peroxide and sodium hydrogen carbonate. A significantly amplified chemiluminescence (CL) from the accelerated decomposition of peroxymonocarbonate (HCO4(-)) by the nanosluster was observed. The CL reaction led to a structure change of BSA and aggregation of Zn/Cu NCs. In the presence of H2O2, Zn/Cu-S bonding between BSA scaffolds and the encapsulated Zn/Cu@BSA NC was oxidized to form a disulfide product. Zn/Cu@BSA NCs were prone to aggregate to form larger nanoparticles without the protection of scaffolds. It is revealed that the strong CL emission was initiated from the catalysis of Zn/Cu@BSA NC and the surface plasmon coupling of the formed Zn/Cu nanoparticles in a single chemical reaction. This amplified CL was successfully exploited for selective sensing of hydrogen peroxide in environmental samples.
authors: MOE Key Laboratory of Wooden Material Science and Application, Beijing Forestry University , Beijing, 100083, China.
authors: Hui
authors: H
authors: Chen
authors: Ling
authors: L
authors: Lin
authors: Haifang
authors: H
authors: Li
authors: Jianzhang
authors: J
authors: Li
authors: Jin-Ming
authors: JM
authors: Lin
mesh_terms: D000818:Animals; D002417:Cattle; D003300:Copper / Q000737:chemistry*; D007700:Kinetics; D049449:Luminescence; D053768:Metal Nanoparticles / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D015032:Zinc / Q000737:chemistry*
chemical_list: D012710:Serum Albumin, Bovine; D003300:Copper; D015032:Zinc
keywords: chemiluminescence; fluorescence; nanoclusters; nanoparticles; surface plasmon resonance