title: Quality of reporting of randomised controlled trials of herbal interventions in ASEAN Plus Six Countries: a systematic review.
abstract: BACKGROUND
  Many randomised controlled trials (RCTs) of herbal interventions have been conducted in the ASEAN Communities. Good quality reporting of RCTs is essential for assessing clinical significance. Given the importance ASEAN placed on herbal medicines, the reporting quality of RCTs of herbal interventions among the ASEAN Communities deserved a special attention.
  
  
  OBJECTIVE
  To systematically review the quality of reporting of RCTs of herbal interventions conducted in the ASEAN Plus Six Countries.
  
  
  METHODS
  Searches were performed using PubMed, EMBASE, The Cochrane Library, and Allied and Complementary Medicine (AMED), from inception through October 2013. These were limited to studies specific to humans and RCTs. Herbal species search terms were based on those listed in the National List of Essential Medicines [NLEM (Thailand, 2011)]. Studies conducted in the ASEAN Plus Six Countries, published in English were included.
  
  
  RESULTS
  Seventy-one articles were identified. Thirty (42.25%) RCTs were from ASEAN Countries, whereas 41 RCTs (57.75%) were from Plus Six Group. Adherence to the recommended CONSORT checklist items for reporting of RCTs of herbal interventions among ASEAN Plus Six Countries ranged from 0% to 97.18%. Less than a quarter of the RCTs (18.31%) reported information on standardisation of the herbal products. However, the scope of our interventions of interest was limited to those developed from 20 herbal species listed in the NLEM of Thailand.
  
  
  CONCLUSIONS
  The present study highlights the need to improve reporting quality of RCTs of herbal interventions across ASEAN Plus Six Communities.
authors: Faculty of Public Health, Naresuan University, Phitsanulok, Thailand.
authors: Chayanin
authors: C
authors: Pratoomsoot
authors: Center of Pharmaceutical Outcomes Research, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand; Department of Population Medicine, Drug Policy Research Group, Harvard Medical School & Harvard Pilgrim Health Care Institute, Boston, MA, United States of America.
authors: Rosarin
authors: R
authors: Sruamsiri
authors: Center of Pharmaceutical Outcomes Research, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand; Center for Pharmacoepidemiology and Pharmacoeconomic Research and Department of Pharmacy Systems, Outcomes and Policy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, United States of America.
authors: Piyameth
authors: P
authors: Dilokthornsakul
authors: Center of Pharmaceutical Outcomes Research, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Selangor, Malaysia; School of Population Health, Public Health Building, University of Queensland, Herston, Australia; School of Pharmacy, University of Wisconsin, Madison, WI, United States of America.
authors: Nathorn
authors: N
authors: Chaiyakunapruk
mesh_terms: D006801:Humans; D033181:Information Dissemination; D008517:Phytotherapy; D016032:Randomized Controlled Trials as Topic
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