title: Validation of the Malay version of the Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO-41) in Malaysia.
abstract: OBJECTIVE
  To assess the validity and reliability of the Malay version of the Quality of Life (QOL) Questionnaire of the European Foundation for Osteoporosis (QUALEFFO-41) in Malaysia.
  
  
  METHODS
  The QUALEFFO-41 was translated from English to Malay and administered to 215 post-menopausal osteoporotic women ≥50 years who could understand Malay, at baseline and 4 weeks. The SF-36 was administered at baseline to assess convergent validity. To assess discriminative validity, patients with and without back pain were recruited.
  
  
  RESULTS
  Confirmatory factor analysis showed that the QUALEFFO-41 had five domains. Good internal consistency was seen in all domains (0.752-0.925) except for the social activity domain (0.692). Test-retest reliability showed adequate correlation for all items (0.752-0.964, p < 0.001). Patients with back pain had significantly worse QOL compared with those without (back pain = 42.2 ± 10.9, no back pain = 33.3 ± 8.9; p < 0.001). The total QUALEFFO-41 score and the SF-36 physical and mental composite scores were significantly correlated (-0.636 and -0.529, p < 0.001, respectively).
  
  
  CONCLUSIONS
  The Malay version of the QUALEFFO-41 was found to be a reliable and valid instrument to evaluate the QOL of osteoporotic patients in Malaysia. To enable the QUALEFFO-41 to be used in a multiracial population, further studies should look into validating other versions of the QUALEFFO-41 in Malaysia.
authors: Department of Primary Care Medicine, University of Malaya Primary Care Research Group (UMPCRG), Kuala Lumpur, Malaysia.
authors: Thiagarajan
authors: T
authors: Nagammai
authors: Mohamed
authors: M
authors: Mohazmi
authors: Su May
authors: SM
authors: Liew
authors: Karuthan
authors: K
authors: Chinna
authors: Pauline Siew Mei
authors: PS
authors: Lai
mesh_terms: D000368:Aged; D001416:Back Pain / Q000523:psychology; D005006:Ethnicity; D005260:Female; D006801:Humans; D007802:Language; D008296:Malaysia; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D010024:Osteoporosis / Q000523:psychology*; D010865:Pilot Projects; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires; D014175:Translating; D014177:Translations
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