title: Scaffolds for tendon and ligament repair and regeneration.
abstract: Enhanced tendon and ligament repair would have a major impact on orthopedic surgery outcomes, resulting in reduced repair failures and repeat surgeries, more rapid return to function, and reduced health care costs. Scaffolds have been used for mechanical and biologic reinforcement of repair and regeneration with mixed results. This review summarizes efforts made using biologic and synthetic scaffolds using rotator cuff and ACL as examples of clinical applications, discusses recent advances that have shown promising clinical outcomes, and provides insight into future therapy.
authors: Synthasome, Inc., 3030 Bunker Hill Street, Suite 308, San Diego, CA, 92109, USA, anthonyratcliffe@synthasome.com.
authors: Anthony
authors: A
authors: Ratcliffe
authors: David L
authors: DL
authors: Butler
authors: Nathaniel A
authors: NA
authors: Dyment
authors: Paul J
authors: PJ
authors: Cagle
authors: Christopher S
authors: CS
authors: Proctor
authors: Seena S
authors: SS
authors: Ratcliffe
authors: Evan L
authors: EL
authors: Flatow
mesh_terms: D000818:Animals; D006801:Humans; D008022:Ligaments / Q000502:physiology* / Q000601:surgery; D012038:Regeneration; D013710:Tendons / Q000502:physiology* / Q000601:surgery; D054457:Tissue Scaffolds
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