title: Study of the therapy of multiple myeloma monoclonal antibody.
abstract: This paper aims to discuss the initial clinical effect of treating bone defect of long bone osteomyelitis with Masquelet technology. A retrospective analysis was made among the recruited 25 patients with long bone osteomyelitis patients from April, 2013 to February 2014 from Henan Provincial People's Hospital. Clinical effect of treating long bone osteomyelitis with Masquelet technology and the possible effects of vancomycin in different doses on knitting were also evaluated in follow-up visit lasting for 6~18 months, and 22 cases' bone was healed on imaging at the last follow up. According to Samantha X ray score criteria, Samantha score of regular dose group and high dose group in 4 months after operation was 4.16 and 3.09, respectively. There were 12 cases in regular-dose antibiotic group, among which, 1 case had delayed wound healing, and 3 cases reoccurred; there were 10 cases in high-dose antibiotic group, among which, no cases reoccurred after operation. Masquelet technology is a reliable and easy osteomyelitis treatment. Notably, it shows significant advantages for long bone reconstruction induced by infection and trauma. Bone cement with high dose of vancomycin has better effect on controlling osteomyelitis than bone cement with regular dose of vancomycin.
authors: Department of Orthopaedics, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
authors: Song
authors: S
authors: Gao
authors: Department of Orthopaedics, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
authors: Shujian
authors: S
authors: Tian
authors: Department of Orthopaedics, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
authors: Jianping
authors: J
authors: Luo
authors: Department of Orthopaedics, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
authors: Guang
authors: G
authors: Yang
authors: Department of Orthopaedics, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, China.
authors: Yuchao
authors: Y
authors: Su
mesh_terms: D000328:Adult; D000368:Aged; D001842:Bone and Bones / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications*; D010019:Osteomyelitis / Q000601:surgery*; D019651:Plastic Surgery Procedures; D012189:Retrospective Studies; D014640:Vancomycin / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D014640:Vancomycin