title: Care of the child with Ebola virus disease.
abstract: OBJECTIVE
  To provide clinicians with practical considerations for care of children with Ebola virus disease in resource-rich settings.
  
  
  METHODS
  Review of the published medical literature, World Health Organization and government documents, and expert opinion.
  
  
  RESULTS
  There are limited data regarding Ebola virus disease in children; however, reported case-fatality proportions in children are high. Ebola virus may affect immune regulation and endothelial function differently in children than adults. Considerations for care of children with Ebola virus disease are presented.
  
  
  CONCLUSIONS
  Ebola virus disease is a severe multisystem disease with high mortality in children and adults. Hospitals and clinicians must prepare to provide care for patients with Ebola virus disease before such patients present for care, with particular attention to rigorous infection control to limit secondary cases. Although there is no proven specific treatment for Ebola virus disease, meticulous supportive care offers patients the best chance of survival.
authors: 1Division of Pediatric Critical Care, Department of Pediatrics, Oregon Health & Science University, Portland, OR. 2Influenza Division, National Center for Immunization and Respiratory Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, GA. 3Department of Critical Care, Mount Sinai Hospital, Toronto, ON, Canada. 4Pediatric Critical Care Medicine, Seattle Children's Hospital and Harborview Medical Center, Seattle, WA. 5Pediatric Critical Care Medicine, Virginia Tech Carilion School of Medicine, Roanoke, VA. 6National Center for Disaster Preparedness, Columbia University, New York, NY. 7Departments of Pediatrics and Emergency Medicine, British Columbia's Children's Hospital, Vancouver, BC, Canada.
authors: Carl O
authors: CO
authors: Eriksson
authors: Timothy M
authors: TM
authors: Uyeki
authors: Michael D
authors: MD
authors: Christian
authors: Mary A
authors: MA
authors: King
authors: Dana A V
authors: DA
authors: Braner
authors: Robert K
authors: RK
authors: Kanter
authors: Niranjan
authors: N
authors: Kissoon
mesh_terms: D002648:Child; D003131:Combined Modality Therapy; D019049:Developed Countries; D019142:Hemorrhagic Fever, Ebola / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy* / Q000635:transmission; D006801:Humans; D017053:Infection Control / Q000379:methods; D008991:Monitoring, Physiologic