title: Prevention of stent thrombosis: challenges and solutions.
abstract: Stent thrombosis is an uncommon but serious complication which carries with it significant mortality and morbidity. This review analyzes the entity of stent thrombosis from a historical and clinical perspective, and chronicles the evolution of this condition through the various generations of stent development, from bare metal to first-generation, second-generation, and third-generation drug-eluting stents. It also delineates the specific risk factors associated with stent thrombosis and comprehensively examines the literature related to each of these risks. Finally, it highlights the preventative strategies that can be garnered from the existing data, and concludes that a multifactorial approach is necessary to combat the occurrence of stent thrombosis, with higher risk groups, such as patients with ST segment elevation myocardial infarction, meriting further research.
authors: Division of Cardiology, Baystate Medical Center, Springfield, MA, USA.
authors: Risheen
authors: R
authors: Reejhsinghani
authors: Division of Cardiology, Baystate Medical Center, Springfield, MA, USA.
authors: Amir S
authors: AS
authors: Lotfi
mesh_terms: D000818:Animals; D003328:Coronary Thrombosis / Q000209:etiology / Q000401:mortality / Q000503:physiopathology / Q000517:prevention & control*; D006801:Humans; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects* / Q000295:instrumentation* / Q000401:mortality; D011474:Prosthesis Design; D012307:Risk Factors; D015607:Stents; D016896:Treatment Outcome
keywords: post-procedural myocardial infarction; preventative strategies; stent thrombosis
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