title: Characteristics of "malignant" vs. "benign" electrocardiographic patterns of early repolarization.
abstract: The electrocardiographic (ECG) pattern of early repolarization (ER) has historically been regarded as a benign ECG variant, but during the past few years, this concept has been challenged based on multiple reports linking the ER pattern with an increased risk of sudden cardiac death. Although the mechanistic basis of ventricular arrhythmogenesis in patients with ER pattern is still incompletely understood, there is increasing information about the ECG and phenotype characteristics of "malignant" vs. "benign" patterns of ER. This review presents the current evidence of markers of "benign" and a more severe nature of ER.
authors: Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland; Emergency Unit, Haartman Hospital, Helsinki, Finland. Electronic address: jani.tikkanen@fimnet.fi.
authors: J T
authors: JT
authors: Tikkanen
authors: Emergency Unit, Haartman Hospital, Helsinki, Finland.
authors: H V
authors: HV
authors: Huikuri
mesh_terms: D000293:Adolescent; D000328:Adult; D056352:Athletes / Q000706:statistics & numerical data*; D054874:Athletic Performance; D001281:Atrial Fibrillation / Q000175:diagnosis* / Q000401:mortality*; D002648:Child; D016757:Death, Sudden, Cardiac / Q000453:epidemiology* / Q000517:prevention & control; D003955:Diagnostic Tests, Routine / Q000706:statistics & numerical data*; D042241:Early Diagnosis; D004562:Electrocardiography / Q000379:methods / Q000706:statistics & numerical data*; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D018580:Mandatory Testing / Q000706:statistics & numerical data; D008403:Mass Screening / Q000706:statistics & numerical data; D011379:Prognosis; D015203:Reproducibility of Results; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D012680:Sensitivity and Specificity; D015996:Survival Rate; D055815:Young Adult
keywords: ECG; Early repolarization; Sudden Cardiac Death