title: Prevalence of Precancerous Conditions and Gastric Cancer Based upon the National Cancer Screening Program in Korea for 7 Years, Single Center Experience.
abstract: Aims. Gastric cancer is the second most prevalent cancer and the third leading cause of cancer-related deaths in Korea. The National Cancer Screening Program (NCSP) has implemented esophagogastroduodenoscopy (EGD) biennially for all Koreans starting in their 40s. This study was conducted to estimate the clinical relevance of NCSP through identifying the prevalence of gastric disease, including cancer. Materials and Methods. Data from 40,821 subjects who received the screening EGD in the single center for 7 years were retrospectively investigated. Results. The overall prevalence of nonatrophic/atrophic/metaplastic gastritis, peptic ulcer, adenoma, early gastric cancer (EGC), and advanced gastric cancer (AGC) was 44.28%, 27.97%, 14.95%, 0.59%, 0.43%, 0.21%, and 0.09%, respectively. The prevalence of metaplastic gastritis, peptic ulcer, adenoma, EGC, and AGC was significantly higher in men than in women. The prevalence of preneoplastic/neoplastic disease significantly increased with age. Judged from the ratio of EGC to AGC, the proportion of EGC made up to 70% of all cancers. Conclusions. Screening endoscopy starting for people in their 40s should be strongly recommended for the elderly. Through the NCSP, the early detection of gastric cancer might contribute to the decreased mortality rate due to gastric cancer in Korea.
authors: Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-773, Republic of Korea.
authors: Ji Hyuk
authors: JH
authors: Kang
authors: Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-773, Republic of Korea.
authors: Yun Jeong
authors: YJ
authors: Lim
authors: Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-773, Republic of Korea.
authors: Jung Hyun
authors: JH
authors: Kang
authors: Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-773, Republic of Korea.
authors: Jae Nam
authors: JN
authors: Yang
authors: Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-773, Republic of Korea.
authors: Seung Min
authors: SM
authors: Shin
authors: Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-773, Republic of Korea.
authors: Jae Hyeuk
authors: JH
authors: Choi
authors: Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27 Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do 410-773, Republic of Korea.
authors: Jin Ho
authors: JH
authors: Lee
references: Best Pract Res Clin Gastroenterol. 2009;23(6):821-7
references: 19942160
references: Jpn J Clin Oncol. 1984 Jun;14(2):169-79
references: 6737707
references: Int J Epidemiol. 1998 Dec;27(6):945-8
references: 10024186
references: Cancer Res Treat. 2014 Apr;46(2):124-30
references: 24851103
references: J Gastroenterol Hepatol. 2008 Apr;23(4):632-7
references: 18397489
references: Int J Cancer. 1983 Apr 15;31(4):421-6
references: 6832853
references: J Clin Gastroenterol. 2010 Mar;44(3):161-6
references: 20042871
references: Eur J Gastroenterol Hepatol. 2009 Aug;21(8):855-60
references: 19369882
references: Br Med J (Clin Res Ed). 1985 Jan 26;290(6464):283
references: 3917787
references: Cancer Res. 1988 Jul 1;48(13):3554-60
references: 3288329
references: Cancer Res. 1990 Aug 1;50(15):4737-40
references: 2369748
references: BMJ. 1991 Mar 30;302(6779):749-52
references: 2021764
references: Cancer Res. 1992 Dec 15;52(24):6735-40
references: 1458460
references: Gastric Cancer. 2001;4(3):132-6
references: 11760078
references: Cancer. 1989 Feb 15;63(4):613-7
references: 2914268
references: Yonsei Med J. 2000 Oct;41(5):607-14
references: 11079621
references: Gut. 2000 Nov;47(5):609
references: 11034572
references: Am J Surg. 1989 Jul;158(1):14-6
references: 2742043
references: World J Gastroenterol. 2006 Apr 28;12(16):2584-7
references: 16688806
references: Int J Cancer. 2002 Feb 20;97(6):811-8
references: 11857360
references: Endoscopy. 2001 Jul;33(7):580-4
references: 11473328
references: Helicobacter. 1996 Mar;1(1):52-6
references: 9398913
references: Dig Dis Sci. 2000 Jul;45(7):1322-9
references: 10961710
references: Cancer Res. 1990 Feb 1;50(3):627-31
references: 2297702