title: [Biological characteristics of human olfactory mucosa mesenchymal stem cells].
abstract: OBJECTIVE
  To observe the biological characteristics of the human olfactory mucosa mesenchymal stem cells (hOM-MSCs).
  
  
  METHODS
  The hOM-MSCs were isolated, cultured and identified in vitro. Scanning electron microscope and transmission electron microscope were used to observe the ultrastructure of hOMMSCs. Th e cells were induced towards adipocyte, osteocyte, neural stem cells, neural-like-cells in vitro.
  
  
  RESULTS
  The hOM-MSCs were mainly in spindle shape, arranged with radial colony. The hOMMSCs expressed CD73 and CD90 but no CD34 and CD45. Th e short and thick microvilli processes were seen at the surface of hOM-MSCs by scanning electron microscope, and 2 different cellular morphology of hOM-MSCs were seen under transmission electron microscope. Moreover, the hOMMSCs could be differentiated into adipocyte, osteocyte, neural stem cells and neural cells.
  
  
  CONCLUSIONS
  The hOM-MSCs possess general biological characteristics of MSCs and display multiple differentiation functions. They can be served as ideal seed cells in tissue-engineering for injury repair.
authors: Department of Neurosurgery, 163 Hospital of PLA; Second Affi liated Hospital, Hunan Normal University, Changsha 410003, China.
authors: Lite
authors: L
authors: Ge
authors: Yi
authors: Y
authors: Zhuo
authors: Da
authors: D
authors: Duan
authors: Zhenyu
authors: Z
authors: Zhao
authors: Xiaohua
authors: X
authors: Teng
authors: Lei
authors: L
authors: Wang
authors: Ming
authors: M
authors: Lu
mesh_terms: D002454:Cell Differentiation; D002478:Cells, Cultured; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D009831:Olfactory Mucosa / Q000166:cytology*