title: Inflammatory pseudotumor of spleen: a case report.
abstract: BACKGROUND
  Inflammatory pseudotumor of spleen is an extremely rare benign condition of uncertain etiology that presents with nonspecific symptoms or as an incidental finding in patients studied by other processes. Since the first description in 1984 by Cotelingam and Jaffe, only 114 cases have been reported.
  
  
  METHODS
  We present a case of a fifty-six years old woman with a splenic injury in ultrasound and computed tomography. The patient undergoes laparoscopic splenectomy and the histologic study of the specimen revealed findings consistent with inflammatory pseudotumor of spleen.
  
  
  CONCLUSIONS
  This rare entity whose pathogenesis is still unknown, can present with nonspecific symptoms. Radiologic studies may lead the diagnosis being useful CT and MRI. The definitive diagnosis is established with the histological findings, characterized by the presence of inflammatory cells with areas of necrosis and fibrosis. There are multiple differentials diagnoses: metastasis, lymphoma, splenic infarction, hemangiomas, vascular malformations, lymphangioma, plasmacytoma, reactive lymphoid hyperplasia, abscess and infectious granulomatous processes; therefore suspicion of malignant neoplasm must be considered, being indicated splenectomy to confirm the diagnosis.
  
  
  CONCLUSIONS
  Inflammatory pseudotumor of spleen is a benign disease, in which diagnostic approach must bear in mind the possibility of a malignant lesion. For this reason, the surgical approach is appropriate to confirm the diagnosis and rule out malignancy with histology.
authors: Department of General Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain. Electronic address: pugalde13@gmail.com.
authors: Paúl
authors: P
authors: Ugalde
authors: Department of General Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors: Carmen
authors: C
authors: García Bernardo
authors: Department of General Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors: Pablo
authors: P
authors: Granero
authors: Department of General Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors: Alberto
authors: A
authors: Miyar
authors: Department of General Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors: Carmen
authors: C
authors: González
authors: Department of General Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors: Ignacio
authors: I
authors: González-Pinto
authors: Department of General Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors: Luis
authors: L
authors: Barneo
authors: Department of General Surgery, Hospital Universitario Central de Asturias, Oviedo, Spain.
authors: Lino
authors: L
authors: Vazquez
keywords: Inflammatory pseudotumor; Spleen; Splenectomy
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