title: An updated report on the trends in cancer incidence and mortality in Japan, 1958-2013.
abstract: The analysis of cancer trends in Japan requires periodic updating. Herein, we present a comprehensive report on the trends in cancer incidence and mortality in Japan using recent population-based data. National cancer mortality data between 1958 and 2013 were obtained from published vital statistics. Cancer incidence data between 1985 and 2010 were obtained from high-quality population-based cancer registries of three prefectures (Yamagata, Fukui and Nagasaki). Joinpoint regression analysis was performed to examine the trends in age-standardized rates of cancer incidence and mortality. All-cancer mortality decreased from the mid-1990s, with an annual percent change of -1.3% (95% confidence interval [CI]: -1.4, -1.3). During the most recent 10 years, over 60% of the decrease in cancer mortality was accounted for by a decrease in stomach and liver cancers (63% for males and 66% for females). The long-term increase in female breast cancer mortality, beginning in the 1960s, plateaued in 2008. All-cancer incidence continuously increased, with annual percent changes of 0.6% (95% CI: 0.5, 0.8) between 1985 and 2005, and 1.8% (95% CI: 0.6, 2.9) between 2005 and 2010. During the most recent 10 years, almost half of the increase in cancer incidence was accounted for by an increase in prostate cancer (60%) in males and breast cancer (46%) in females. The cancer registry quality indices also began to increase from ∼2005. Decreases in stomach and liver cancers observed for incidence and mortality reflect the reduced attribution of infection-related factors (i.e. Helicobacter pylori and hepatitis virus). However, it should be noted that cervical cancer incidence and mortality rates began to increase from ∼1990.
authors: Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo kkatanod@ncc.go.jp.
authors: Kota
authors: K
authors: Katanoda
authors: Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo.
authors: Megumi
authors: M
authors: Hori
authors: Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo.
authors: Tomohiro
authors: T
authors: Matsuda
authors: Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo.
authors: Akiko
authors: A
authors: Shibata
authors: Division of Cancer Epidemiology and Prevention, Miyagi Cancer Center Research Institute, Natori.
authors: Yoshikazu
authors: Y
authors: Nishino
authors: Department of Cancer Therapy Center, Fukui Prefectural Hospital, Fukui.
authors: Masakazu
authors: M
authors: Hattori
authors: Department of Epidemiology, Radiation Effects Research Foundation, Nagasaki.
authors: Midori
authors: M
authors: Soda
authors: Center for Cancer Control and Statistics, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka.
authors: Akiko
authors: A
authors: Ioka
authors: Division of Environmental Medicine and Population Sciences, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.
authors: Tomotaka
authors: T
authors: Sobue
authors: Cancer Information Services and Surveillance Division, Center for Cancer Control and Information Services, National Cancer Center, Tokyo.
authors: Hiroshi
authors: H
authors: Nishimoto
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People / Q000706:statistics & numerical data*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009026:Mortality / Q000639:trends; D009369:Neoplasms / Q000453:epidemiology*; D044382:Population Groups; D012042:Registries / Q000706:statistics & numerical data; D012044:Regression Analysis; D012307:Risk Factors; D055815:Young Adult
keywords: cancer; incidence; mortality; neoplasms; population surveillance