title: An unusual side effect of Ibuprofen post dental therapy: increased erectile and libido activity.
abstract: Nonsteroidal anti-inflammatory drugs are the most commonly used medications for pain control in dentistry. The reported adverse effects include gastrointestinal and cardiovascular events, alterations in renal function, and effects on blood pressure, hepatic injury, and platelet inhibition which can lead to increased bleeding. This case report describes an unusual rare adverse event of the use of ibuprofen for pain control post restorative treatment. A 26-year-old, otherwise healthy Saudi male reported an unusual side effect of increased libido and erectile function post use of ibuprofen. The medical and laboratory tests have failed to identify a link between this rare adverse event and either underlying conditions or possibly related etiology. This case represented a puzzling challenge with no clear explanation.
authors: Assistant Professor, Department of Oral and Maxillofacial Sciences, Al-Farabi College for Dentistry and Nursing, Riyadh, Saudi Arabia.
authors: Omar
authors: O
authors: Kujan
authors: Lecturer, Department of Oral and Maxillofacial Sciences, Al-Farabi College for Dentistry and Nursing, Riyadh, Saudi Arabia.
authors: Syed Ahmed
authors: SA
authors: Raheel
authors: Assistant Professor, Department of Oral and Maxillofacial Sciences, Al-Farabi College for Dentistry and Nursing, Riyadh, Saudi Arabia.
authors: Saleh
authors: S
authors: Azzeghaiby
authors: Assistant Professor, Department of Restorative Dental Sciences, Al-Farabi College for Dentistry and Nursing, Riyadh, Saudi Arabia.
authors: Fahad Hussain
authors: FH
authors: Alqahtani
authors: Consultant, Department of Dentistry, College of Medicine and University Hospitals, King Saud University, Riyadh, Saudi Arabia.
authors: Mohammed
authors: M
authors: Alshehri
authors: Lecturer, Department of Clinical Pharmacology, Faculty of Pharmacy, Al-Baath University, Homs, Syria.
authors: Shahama
authors: S
authors: Taifour
keywords: Erectile; ibuprofen; side effects
references: J Basic Clin Physiol Pharmacol. 2011 Nov 23;22(4):137-40
references: 22865435
references: Periodontol 2000. 2008;46:143-64
references: 18201349
references: J Fam Pract. 1989 Aug;29(2):210-1
references: 2526860
references: Clin Med Res. 2007 Mar;5(1):19-34
references: 17456832
references: Pharmacoepidemiol Drug Saf. 2008 Feb;17(2):211-2
references: 18236511
references: Bipolar Disord. 2013 Sep;15(6):650-6
references: 23924261