title: Control of ciliation in embryogenesis.
abstract: The protrusion of cilia into extracellular space provides cells with sensors of localized environmental cues that include fluid flow, mechanical force and important growth factors such as Hedgehog. Live imaging has now captured the initial appearance of cilia during embryogenesis, and defined lineage-specific determinants that restrict extra-embryonal ciliogenesis.
authors: Program in Molecular Therapeutics, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.
authors: Anna S
authors: AS
authors: Nikonova
authors: Program in Molecular Therapeutics, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.
authors: Erica A
authors: EA
authors: Golemis
mesh_terms: D000818:Animals; D019070:Cell Lineage; D002923:Cilia / Q000378:metabolism*; D004622:Embryo, Mammalian / Q000166:cytology* / Q000378:metabolism*; D005260:Female; D011247:Pregnancy
references: Nat Cell Biol. 2015 Feb;17(2):113-22
references: 25599390
references: Cell Mol Life Sci. 2013 Feb;70(4):661-87
references: 22864622
references: Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11325-30
references: 16061793
references: Cell. 2007 Aug 24;130(4):678-90
references: 17719545
references: Cell Cycle. 2014;13(18):2859-68
references: 25486474
references: Dev Cell. 2010 Jul 20;19(1):66-77
references: 20643351
references: Curr Opin Cell Biol. 2013 Aug;25(4):506-11
references: 23747070
references: Drug Discov Today Dis Mech. 2013 Dec 1;10(3-4):e135-e142
references: 24982684
references: Cell. 2007 Jun 29;129(7):1351-63
references: 17604723
references: Cell. 2012 Nov 9;151(4):847-58
references: 23141541
references: J Am Soc Nephrol. 2010 Dec;21(12 ):2041-6
references: 20864688
references: Annu Rev Genet. 2013;47:353-76
references: 24016188
references: Dev Cell. 2004 Mar;6(3):445-51
references: 15030766
references: Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8541-6
references: 24853502
references: Genome Med. 2011 Sep 26;3(9):59
references: 21943201