title: The Relationship between Eating and Lifestyle Habits and Cancer in Van Lake Region: Another Endemic Region for Esophageal and Gastric Cancers.
abstract: Purpose. To examine the relationship between esophageal and gastric cancers commonly seen in Van Lake region and the traditional eating habits of the geography. Materials and Methods. Esophageal and gastric cancer cases, who underwent surgery between January 1, 2012, and December 31, 2013, were examined. Pathology reports of the patients and presence of Helicobacter pylori (HP) were recorded. Surveys were filled by face to face meeting or telephone call. Control group was created with randomly selected individuals without any cancer diagnosis having age, gender, and socioeconomic characteristics similar to patient group. All data were analyzed using SAS.9.3 statistical programme. Results. Compared with the control group, herby cheese consumption (a component of eating habits) and smoking were significantly higher in the patient group (P < 0.001). Tandoor exposure is compared in terms of female gender, and significant difference was found between the groups (P = 0.0013). As a result of the analysis with logistic regression more than 150 gr of herby cheese consumption per day was found to increase the cancer risk (odds ratio 1.017; 95% CI: 1.012-1.022). Conclusion. A high consumption of herby cheese, cooking bread on tandoor, and heavy smoking were seen to be important risk factors for esophageal and gastric cancers.
authors: General Surgery Department, Faculty of Medicine, Van Yüzüncü Yıl University, 65080 Van, Turkey.
authors: Sebahattin
authors: S
authors: Celik
authors: General Surgery Clinic, Van Regional Training and Research Hospital, 65100 Van, Turkey.
authors: E Murat
authors: EM
authors: Yılmaz
authors: Pathology Clinic, Van Regional Training and Research Hospital, 65100 Van, Turkey.
authors: Ferhat
authors: F
authors: Özden
authors: General Surgery Department, Faculty of Medicine, Van Yüzüncü Yıl University, 65080 Van, Turkey.
authors: Cetin
authors: C
authors: Kotan
authors: Department of Biometry and Genetics, Faculty of Agriculture, Van Yüzüncü Yıl University, 65080 Van, Turkey.
authors: Hayrettin
authors: 0000-0003-4084-8404
authors: H
authors: Okut
references: Oncogene. 2004 Aug 23;23(38):6329-40
references: 15322508
references: IARC Monogr Eval Carcinog Risks Hum. 1993;56:83-113
references: 8411630
references: IARC Monogr Eval Carcinog Risks Hum. 2004;83:1-1438
references: 15285078
references: Gastroenterol Clin North Am. 2009 Mar;38(1):27-57, vii
references: 19327566
references: Int J Cancer. 2009 Sep 15;125(6):1424-30
references: 19449378
references: Int J Cancer. 2006 Jun 15;118(12):3030-44
references: 16404738
references: IARC Monogr Eval Carcinog Risks Hum. 1994;61:1-241
references: 7715068
references: Cancer Prev Res (Phila). 2008 Oct;1(5):329-38
references: 19138977
references: BMJ. 2009 Mar 26;338:b929
references: 19325180
references: Asian Pac J Cancer Prev. 2013;14(3):1669-76
references: 23679254
references: CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90
references: 21296855
references: Front Biosci (Landmark Ed). 2009 Jan 01;14(4):1490-504
references: 19273142
references: World J Gastroenterol. 2009 May 14;15(18):2204-13
references: 19437559
references: Int J Cancer. 2009 Aug 1;125(3):491-524
references: 19415743
references: Turk J Gastroenterol. 2003 Mar;14(1):50-3
references: 14593538