title: Direct arylation of sydnones with aryl chlorides toward highly substituted pyrazoles.
abstract: The direct arylation of the C4 position of both N-alkyl- and N-arylsydnones with aryl/heteroaryl chlorides has been realized. The reaction is quite general and allows access to a wide range of 4-substituted sydnones. Yields of more challenging substrates can be improved through the use of aryl bromides.
authors: Department of Chemistry, University of Sheffield , Brook Hill, S3 7HF, U.K.
authors: Andrew W
authors: AW
authors: Brown
authors: Joseph P A
authors: JP
authors: Harrity
mesh_terms: D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D015394:Molecular Structure; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry; D013558:Sydnones / Q000737:chemistry*
chemical_list: D006843:Hydrocarbons, Chlorinated; D011720:Pyrazoles; D013558:Sydnones