title: Integrating NIMH Research Domain Criteria (RDoC) into Depression Research.
abstract: The NIMH Research Domain Criteria (RDoC) initiative grew out of the agency's goal to develop "new ways of classifying mental disorders based on behavioral dimensions and neurobiological measures" (NIMH, 2008). In this article, we review how depression research can be meaningfully conducted within an RDoC framework, with a particular focus on the negative valence systems construct of Loss. New efforts to understand depression within the context of RDoC must seek an integrative understanding of the disorder across multiple units of analysis from genes to neural circuits to behavior. In addition, the constructs or processes must be understood within the context of specific environmental and developmental influences. Key concepts are discussed and we end by highlighting research on rumination as a prime example of research that is consistent with RDoC.
authors: Binghamton University (SUNY).
authors: Mary L
authors: ML
authors: Woody
authors: Binghamton University (SUNY).
authors: Brandon E
authors: BE
authors: Gibb
references: Brain Cogn. 2013 Apr;81(3):352-9
references: 23485025
references: Annu Rev Clin Psychol. 2010;6:285-312
references: 20192795
references: J Abnorm Child Psychol. 2013 Nov;41(8):1289-98
references: 23690281
references: Clin Child Fam Psychol Rev. 2007 Mar;10(1):1-24
references: 17318382
references: Cogn Affect Behav Neurosci. 2010 Dec;10(4):470-8
references: 21098808
references: Psychophysiology. 2015 May;52(5):722-5
references: 25512247
references: Cogn Affect Behav Neurosci. 2011 Jun;11(2):207-16
references: 21373973
references: Biol Psychiatry. 2001 Apr 1;49(7):624-36
references: 11297720
references: BMC Med. 2013 May 14;11:126
references: 23672542
references: Nat Rev Neurosci. 2011 Jul 06;12 (8):467-77
references: 21731066
references: J Abnorm Child Psychol. 2012 Feb;40(2):317-26
references: 21826445
references: J Abnorm Psychol. 1991 Nov;100(4):569-82
references: 1757671
references: Am J Psychiatry. 2008 Aug;165(8):969-77
references: 18628348
references: J Abnorm Psychol. 2008 Feb;117(1):16-31
references: 18266483
references: Proc Natl Acad Sci U S A. 2014 May 6;111(18):6774-9
references: 24753564
references: Neurosci Lett. 2007 Dec 11;429(1):12-6
references: 17959306
references: J Abnorm Psychol. 2014 Feb;123(1):61-7
references: 24661160
references: J Neurosci. 2007 Aug 15;27(33):8877-84
references: 17699669
references: Depress Anxiety. 2014 Mar;31(3):233-49
references: 24151118
references: J Child Psychol Psychiatry. 2014 Sep;55(9):1009-16
references: 24635760
references: J Abnorm Psychol. 2008 May;117(2):324-33
references: 18489208
references: J Psychosom Res. 2012 Jul;73(1):1-9
references: 22691553
references: Exp Neurol. 2012 Jan;233(1):102-11
references: 22101006
references: Am J Psychiatry. 2012 Jul;169(7):693-703
references: 22535198
references: Cogn Emot. 2014;28(7):1270-86
references: 24499019
references: Hum Brain Mapp. 2009 Jan;30(1):163-74
references: 18041741
references: J Abnorm Psychol. 2013 May;122(2):339-52
references: 23713497
references: Cogn Emot. 2016;30(2):302-14
references: 25648046
references: Genes Brain Behav. 2011 Oct;10(7):740-6
references: 21745335
references: Dev Psychopathol. 2009 Winter;21(1):7-26
references: 19144220
references: Am J Med Genet B Neuropsychiatr Genet. 2013 Sep;162B(6):521-9
references: 23857890
references: Mol Psychiatry. 2013 Apr;18(4):497-511
references: 22472876
references: Perspect Psychol Sci. 2008 Sep;3(5):400-24
references: 26158958
references: J Clin Child Adolesc Psychol. 2016;45(3):270-8
references: 25496371
references: JAMA. 2009 Jun 17;301(23):2462-71
references: 19531786
references: Behav Res Ther. 2008 Nov;46(11):1238-43
references: 18760771
references: World Psychiatry. 2014 Feb;13(1):28-35
references: 24497240
references: Clin Psychol Sci. 2013 Jul 1;1(3):316-322
references: 23956956
references: Br J Psychiatry. 2014 Aug;205(2):113-9
references: 24925986
references: Cogn Affect Behav Neurosci. 2005 Jun;5(2):156-68
references: 16180622
references: Nat Rev Genet. 2010 Apr;11(4):259-72
references: 20212493
references: J Clin Child Adolesc Psychol. 2015;44(2):280-90
references: 24555423
references: Biol Psychiatry. 2014 Sep 1;76(5):350-3
references: 25103538
references: Emotion. 2009 Aug;9(4):579-84
references: 19653783
references: Arch Gen Psychiatry. 2011 May;68(5):444-54
references: 21199959
references: Cogn Affect Behav Neurosci. 2014 Dec;14(4):1259-70
references: 24643765
references: Cogn Emot. 2012;26(5):916-26
references: 22077906
references: J Neurosci. 2013 Mar 6;33(10):4584-93
references: 23467374
references: Clin Psychol Rev. 2010 Jul;30(5):582-93
references: 20478648
references: J Clin Child Adolesc Psychol. 2015 ;44(6):1008-14
references: 25010145
references: Neurosci Biobehav Rev. 2012 Feb;36(2):747-56
references: 22178086
references: J Abnorm Psychol. 2014 Feb;123(1):35-48
references: 24661157
references: Pers Individ Dif. 2013 Aug;55(4):367-374
references: 24089583
references: Biol Psychiatry. 2011 Apr 15;69(8):726-33
references: 21447417
references: Biol Psychiatry. 2010 Sep 1;68(5):484-90
references: 20497900
references: Cogn Emot. 2013;27(2):193-216
references: 22920216