title: Multi-stimulus-responsive shape-memory polymer nanocomposite network cross-linked by cellulose nanocrystals.
abstract: In this study, we developed a thermoresponsive and water-responsive shape-memory polymer nanocomposite network by chemically cross-linking cellulose nanocrystals (CNCs) with polycaprolactone (PCL) and polyethylene glycol (PEG). The nanocomposite network was fully characterized, including the microstructure, cross-link density, water contact angle, water uptake, crystallinity, thermal properties, and static and dynamic mechanical properties. We found that the PEG[60]-PCL[40]-CNC[10] nanocomposite exhibited excellent thermo-induced and water-induced shape-memory effects in water at 37 °C (close to body temperature), and the introduction of CNC clearly improved the mechanical properties of the mixture of both PEG and PCL polymers with low molecular weights. In addition, Alamar blue assays based on osteoblasts indicated that the nanocomposites possessed good cytocompatibility. Therefore, this thermoresponsive and water-responsive shape-memory nanocomposite could be potentially developed into a new smart biomaterial.
authors: Key Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University , Chengdu, Sichuan 610031, P. R. China.
authors: Ye
authors: Y
authors: Liu
authors: Ying
authors: Y
authors: Li
authors: Guang
authors: G
authors: Yang
authors: Xiaotong
authors: X
authors: Zheng
authors: Shaobing
authors: S
authors: Zhou
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D002460:Cell Line; D002470:Cell Survival; D002482:Cellulose / Q000737:chemistry*; D006801:Humans; D053761:Nanocomposites / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D010006:Osteoblasts / Q000166:cytology; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D002482:Cellulose
keywords: cellulose nanocrystals; nanocomposite; shape memory; thermoresponsive; water-responsive