title: Clinical characteristics of individuals with serious mental illness and type 2 diabetes.
abstract: OBJECTIVE
  Data from 157 individuals with serious mental illness and comorbid diabetes enrolled in an ongoing treatment study were used to examine clinical correlates of diabetes control.
  
  
  METHODS
  Factors assessed included depressive symptoms (Montgomery-Åsberg Depression Rating Scale), global psychopathology severity (Brief Psychiatric Rating Scale), and glycosylated hemoglobin (HbA1c), a biomarker of diabetes control.
  
  
  RESULTS
  Seventy-seven participants had depression, 40 had schizophrenia, and 40 had bipolar disorder. Most were moderately to severely depressed with poor diabetes control. No correlation between diagnosis and diabetes control was found after adjustment for gender, race, health literacy, diabetes duration, and diabetes knowledge. Greater depression severity and longer diabetes duration were related to poorer diabetes control. Lower severity of global psychopathology was related to poorer diabetes control, perhaps because of overall low levels of psychosis and mania.
  
  
  CONCLUSIONS
  People with serious mental illness and diabetes face multiple challenges, which, along with severe depression, may impede diabetes self-management.
authors: Dr. Sajatovic and Ms. Cassidy are with the Department of Psychiatry, Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, Cleveland, Ohio (e-mail: martha.sajatovic@uhhospitals.org ). Dr. Gunzler, Dr. Einstadter, Mr. Thomas, Dr. Perzynski, Ms. Kanuch, and Dr. Dawson are with the Center for Health Care Research and Policy, Case Western Reserve University and MetroHealth Medical Center, Cleveland. Dr. McCormick is with the Center for Health Care Research and Policy, Case Western Reserve University.
authors: Martha
authors: M
authors: Sajatovic
authors: Douglas
authors: D
authors: Gunzler
authors: Douglas
authors: D
authors: Einstadter
authors: Charles
authors: C
authors: Thomas
authors: Richard A
authors: RA
authors: McCormick
authors: Adam T
authors: AT
authors: Perzynski
authors: Stephanie
authors: S
authors: Kanuch
authors: Kristin A
authors: KA
authors: Cassidy
authors: Neal V
authors: NV
authors: Dawson
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000453:epidemiology*; D015897:Comorbidity; D003865:Major Depressive Disorder / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000453:epidemiology* / Q000628:therapy; D005260:Female; D006442:Glycated Hemoglobin; D006801:Humans; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D012559:Schizophrenia / Q000453:epidemiology*; D012648:Self Care; D012720:Severity of Illness Index
chemical_list: D006442:Glycated Hemoglobin
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