title: Noninvasive metrics for identification of brain injury deficits in piglets.
abstract: Balance and bispectral index metrics were evaluated in piglets following focal and diffuse brain injury. A significant decrease in bispectral index existed at 24 hours after diffuse brain injury, but not after focal injury. Postural sway increased at 1-6 hours after both focal and diffuse injuries.
authors: a University Laboratory Animal Resources and Department of Pathobiology , School of Veterinary Medicine, University of Pennsylvania , Philadelphia , Pennsylvania.
authors: Samer M
authors: SM
authors: Jaber
authors: Sarah
authors: S
authors: Sullivan
authors: Susan S
authors: SS
authors: Margulies
mesh_terms: D000818:Animals; D001930:Brain Injuries / Q000503:physiopathology* / Q000662:veterinary; D002047:Buprenorphine / Q000008:administration & dosage; D016292:Procedural Sedation; D004569:Electroencephalography / Q000379:methods*; D007273:Injections, Intramuscular; D004856:Postural Balance; D011597:Psychomotor Performance / Q000502:physiology; D011930:Reaction Time; D013552:Swine
chemical_list: D002047:Buprenorphine
references: J Neurosurg. 2000 Sep;93(3):455-62
references: 10969944
references: J Neurotrauma. 2002 Jul;19(7):843-53
references: 12184854
references: Curr Sports Med Rep. 2003 Feb;2(1):24-30
references: 12831673
references: Acad Emerg Med. 2004 Apr;11(4):349-52
references: 15064207
references: J Comp Neurol. 1991 Apr 1;306(1):24-38
references: 2040727
references: J Clin Monit Comput. 2006 Dec;20(6):399-404
references: 16964535
references: Am J Vet Res. 2007 Dec;68(12):1300-7
references: 18052734
references: Gait Posture. 2011 Apr;33(4):594-9
references: 21333541
references: J Neurotrauma. 2011 May;28(5):763-74
references: 21250918
references: J Neuroeng Rehabil. 2012;9:59
references: 22913719
references: Br J Sports Med. 2014 Jan;48(2):135-40
references: 23956336