title: Glucosamine supplementation after anterior cruciate ligament reconstruction in athletes: a randomized placebo-controlled trial.
abstract: Although glucosamine is commonly consumed by athletes, its effectiveness in sports injuries is still under debate. We aimed to investigate the effects of glucosamine to the rehabilitation outcomes of anterior cruciate ligament (ACL) reconstructed athletes. Glucosamine-sulfate (1000 mg daily, for 8 weeks) was administered to half of the cohort of 30 male athletes, the other half used a placebo. Both groups received the same rehabilitation protocol. Knee pain and functions were evaluated by a visual analogue scale (VAS), International Knee Documentation Committee (IKDC) and Lysholm scores before and after oral administration. Additionally, an isokinetic test was performed after the administration period. The scores revealed significant improvements in both groups after 8 weeks, but no significant difference was detected between groups in any of the parameters. Glucosamine supplementation did not improve the rehabilitation outcomes of athletes after ACL reconstruction. This is the first study investigating this topic. Further studies will help to obtain clear evidence about glucosamine efficacy on ACL injured or ACL reconstructed athletes.
authors: a Department of Sports Medicine , Antalya Education and Research Hospital , Antalya , Turkey.
authors: Ali
authors: A
authors: Eraslan
authors: Bulent
authors: B
authors: Ulkar
mesh_terms: D000328:Adult; D000070598:Anterior Cruciate Ligament Injuries; D059549:Anterior Cruciate Ligament Reconstruction / Q000534:rehabilitation*; D001265:Athletic Injuries / Q000534:rehabilitation* / Q000601:surgery; D003131:Combined Modality Therapy; D019587:Dietary Supplements; D004334:Drug Administration Schedule; D005944:Glucosamine / Q000627:therapeutic use*; D006801:Humans; D007718:Knee Injuries / Q000534:rehabilitation* / Q000601:surgery; D008297:Male; D026741:Physical Therapy Modalities; D011182:Postoperative Care / Q000379:methods*; D016037:Single-Blind Method; D016896:Treatment Outcome
chemical_list: D005944:Glucosamine
keywords: ACL injury; athlete; glucosamine