title: Investigation of hematological and biochemical parameters in small ruminants naturally infected with Babesia ovis.
abstract: Babesia ovis plays an important role in causing anemia and kidney dysfunction in affected animals. There are few extensive studies about hematological and biochemical findings of small ruminants' babesiosis caused by B. ovis. The aim of this study was to evaluate the effect of babesiosis on some hematological and biochemical parameters in infected small ruminants with B. ovis. A total of 280 sheep and 122 goats from 40 herds were randomly examined for the presence of B. ovis in blood samples. Of 402 samples, 67 animals (16.7%) were positive for B. ovis of which 52 (18.5%) were sheep and 15 (12.2%) goats, respectively. The infected animals were divided into four subgroups according to parasitemia rates (<1%, 1%, 2%, and 3%). As a control group, 67 uninfected animals were also selected from the same farms. With increase in parasitemia rates, hemoglobin concentration (Hb), packed cell volume (PCV), red blood cells (RBCs), mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC) significantly decreased (P < 0.05), while, total leukocyte count, number of lymphocyte, monocyte, neutrophil and eosinophil showed a significant increase (P < 0.05). Infected animals presented a significant elevation (P < 0.05) of total proteins and significantly lower level (P < 0.05) of albumin compared to non-infected animals. Significant elevation (P < 0.05) of BUN, creatinine, cholestrol, triglyceride, HDL and LDL level were found with parasitemia progression.
authors: Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran;
authors: Bijan
authors: B
authors: Esmaeilnejad
authors: Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran;
authors: Mousa
authors: M
authors: Tavassoli
authors: Department of Clinical Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
authors: Siamak
authors: S
authors: Asri-Rezaei
keywords: Babesia ovis; Biochemical parameters; Hematology; Small ruminant
references: Vet Parasitol. 2008 Nov 7;157(3-4):211-21
references: 18789581
references: Vet J. 2007 Jul;174(1):193-5
references: 16765620
references: Vet Res. 2005 Sep-Dec;36(5-6):713-22
references: 16120247
references: Res Vet Sci. 2009 Feb;86(1):43-8
references: 18599097
references: Zentralbl Veterinarmed A. 1979 May;26(4):327-36
references: 113963
references: Vet Parasitol. 2009 Nov 12;165(3-4):318-22
references: 19679397
references: Vet Parasitol. 2005 Nov 25;134(1-2):77-85
references: 16112810
references: Vet Parasitol. 1988 Mar;27(3-4):209-20
references: 3369074
references: Acta Vet Hung. 2007 Dec;55(4):511-23
references: 18277710
references: Vet Parasitol. 2007 Apr 10;145(1-2):146-51
references: 17157987
references: Ann N Y Acad Sci. 1998 Jun 29;849:21-31
references: 9668446
references: J Vet Med Sci. 2002 Mar;64(3):221-6
references: 11999441
references: J Vet Med B Infect Dis Vet Public Health. 2003 Mar;50(2):60-2
references: 12675895
references: Infect Immun. 2000 Sep;68(9):5139-45
references: 10948137
references: Chem Immunol. 1997;68:136-52
references: 9329220
references: Parasitol Today. 1988 Aug;4(8):214-8
references: 15463101
references: Res Vet Sci. 2008 Aug;85(1):116-9
references: 17881019
references: Vet Parasitol. 1983 Feb;12(1):1-11
references: 6683035
references: Vet Parasitol. 2008 Mar 25;152(1-2):60-6
references: 18164550
references: Vet Parasitol. 1991 Jan;38(1):1-12
references: 2024425
references: Vet Med Nauki. 1977;14(2):50-6
references: 919337
references: Vet Parasitol. 2009 May 26;162(1-2):7-15
references: 19269099
references: J Parasitol. 2000 Aug;86(4):736-42
references: 10958449
references: Vet Parasitol. 1998 Jan 31;74(2-4):153-63
references: 9561703
references: Vet Parasitol. 2006 May 31;138(1-2):3-10
references: 16513280
references: Vet Clin Pathol. 2001;30(4):180-188
references: 12024299
references: Parasitol Res. 2003 Feb;89(3):228-34
references: 12541066
references: Vet Parasitol. 2007 Oct 21;149(1-2):65-71
references: 17709209
references: Ann N Y Acad Sci. 1996 Jul 23;791:136-47
references: 8784495
references: Parasitol Res. 2007 Mar;100(4):797-802
references: 17096146
references: Vet Parasitol. 2009 Dec 23;166(3-4):205-11
references: 19765903
references: Vet Parasitol. 1999 Sep 1;85(4):319-24
references: 10488734