title: Trade-off between information format and capacity in the olfactory system.
abstract: As information about the sensory environment passes between layers within the nervous system, the format of the information often changes. To examine how information format affects the capacity of neurons to represent stimuli, we measured the rate of information transmission in olfactory neurons in intact, awake locusts (Schistocerca americana) while pharmacologically manipulating patterns of correlated neuronal activity. Blocking the periodic inhibition underlying odor-elicited neural oscillatory synchronization increased information transmission rates. This suggests oscillatory synchrony, which serves other information processing roles, comes at a cost to the speed with which neurons can transmit information. Our results provide an example of a trade-off between benefits and costs in neural information processing.
authors: NIH-NICHD, Laboratory of Cellular and Synaptic Physiology, Bethesda, Maryland 20892 zane.aldworth@nih.gov.
authors: Zane N
authors: http://orcid.org/0000-0002-0647-8465
authors: ZN
authors: Aldworth
authors: NIH-NICHD, Laboratory of Cellular and Synaptic Physiology, Bethesda, Maryland 20892.
authors: Mark A
authors: http://orcid.org/0000-0001-9200-1884
authors: MA
authors: Stopfer
mesh_terms: D000200:Action Potentials / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D057506:Arthropod Antennae / Q000166:cytology / Q000502:physiology; D003198:Computer Simulation; D005260:Female; D058787:GABA-A Receptor Antagonists / Q000494:pharmacology; D006110:Grasshoppers; D008297:Male; D008959:Models, Neurological; D009433:Neural Inhibition / Q000502:physiology; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D017711:Nonlinear Dynamics; D009812:Odorants; D009830:Olfactory Bulb / Q000166:cytology* / Q000187:drug effects / Q000502:physiology*; D010852:Picrotoxin / Q000494:pharmacology; D025341:Principal Component Analysis
chemical_list: D058787:GABA-A Receptor Antagonists; D010852:Picrotoxin
keywords: information theory; neural coding; oscillations; synchrony
references: J Neurosci. 2007 Feb 14;27(7):1659-69
references: 17301174
references: J Neurosci. 2005 May 25;25(21):5195-206
references: 15917459
references: Neuron. 2005 May 5;46(3):483-92
references: 15882647
references: Science. 1996 Nov 8;274(5289):976-9
references: 8875938
references: Neuron. 2003 Sep 11;39(6):991-1004
references: 12971898
references: Network. 2001 May;12(2):199-213
references: 11405422
references: J Neurosci. 2011 Jun 15;31(24):8699-705
references: 21677152
references: J Neurosci. 2003 Dec 17;23(37):11539-53
references: 14684857
references: Nature. 2007 Aug 9;448(7154):709-13
references: 17581587
references: Nature. 2001 Jun 7;411(6838):698-701
references: 11395773
references: Science. 1995 Nov 17;270(5239):1207-10
references: 7502047
references: Nature. 2001 Mar 22;410(6827):466-70
references: 11260713
references: Nature. 2008 Aug 21;454(7207):995-9
references: 18650810
references: J Neurosci. 2009 Jul 1;29(26):8595-603
references: 19571150
references: Science. 2002 Jul 19;297(5580):359-65
references: 12130775
references: J Neurosci. 2011 Nov 2;31(44):15732-41
references: 22049416
references: Neuron. 2009 Dec 10;64(5):692-706
references: 20005825
references: Neural Comput. 2001 Apr;13(4):717-49
references: 11255566
references: Nat Rev Neurosci. 2002 Nov;3(11):884-95
references: 12415296
references: Neuron. 2006 Aug 17;51(4):467-82
references: 16908412
references: Neuron. 2005 Nov 23;48(4):661-73
references: 16301181
references: Science. 1994 Sep 23;265(5180):1872-5
references: 17797226
references: J Neurosci Methods. 2002 Dec 31;122(1):43-57
references: 12535763
references: Nat Neurosci. 2005 Nov;8(11):1568-76
references: 16222230
references: Nature. 1997 Nov 6;390(6655):70-4
references: 9363891
references: Nature. 1998 Oct 15;395(6703):693-8
references: 9790189
references: J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2011 Jun;197(6):653-65
references: 21286727
references: Neuron. 2009 Feb 26;61(4):570-86
references: 19249277
references: J Neurosci. 2004 Jun 30;24(26):6037-47
references: 15229251
references: Neuron. 1999 Sep;24(1):49-65, 111-25
references: 10677026
references: Nature. 1999 Dec 9;402(6762):664-8
references: 10604472
references: Biophys J. 1999 Feb;76(2):691-708
references: 9929474
references: J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2009 Jan;195(1):39-54
references: 19018543
references: Behav Neurosci. 2000 Jun;114(3):514-25
references: 10883802
references: Annu Rev Entomol. 2010;55:399-420
references: 19737085
references: Neuron. 1999 Sep;24(1):31-47, 111-25
references: 10677025
references: J Neurophysiol. 1993 May;69(5):1484-98
references: 8389826
references: J Neurosci. 2012 Jun 13;32(24):8138-48
references: 22699895
references: Science. 2014 Jun 27;344(6191):1515-8
references: 24970087
references: J Neurosci. 1996 Jun 15;16(12):3837-47
references: 8656278
references: Nat Neurosci. 2010 Oct;13(10):1276-82
references: 20802489
references: J Neurophysiol. 2010 Aug;104(2):1007-19
references: 20505124
references: Trends Neurosci. 2004 Apr;27(4):225-30
references: 15046882
references: J Exp Biol. 1999 Jun;202 (Pt 12):1639-48
references: 10333509