title: Effect of hypothermia in patients undergoing simultaneous carotid endarterectomy and coronary artery bypass graft surgery.
abstract: OBJECTIVE
  We sought to determine whether hypothermia provided any benefit in patients undergoing simultaneous coronary artery bypass graft surgery (CABG) and carotid endarterectomy (CEA) using one of two different surgical strategies.
  
  
  METHODS
  Group 1 patients (n = 34, 88.2% male, mean age 65.94 ± 6.67 years) underwent CEA under moderate hypothermia before cross clamping the aorta, whereas group 2 patients (n = 23, 69.6% male, mean age 65.78 ± 9.29 years) underwent CEA under normothermic conditions before initiating cardiopulmonary bypass (CPB). Primary outcome of interest was the occurrence of any new neurological event.
  
  
  RESULTS
  The two groups were similar in terms of baseline characteristics. Permanent impairment occurred in one patient (2.9%) in group 1. One patient from each group (2.9 and 4.37%) had transient neurological events and they recovered completely on the sixth and 11th postoperative days, respectively. Overall, there was no statistically significant difference between the two groups with regard to occurrence of early neurological outcomes (n = 2, 5.8 % vs n = 1, 4.3 %, p = 0.12).
  
  
  CONCLUSIONS
  This study could not provide evidence regarding benefit of hypothermia in simultaneous operations for carotid and coronary artery disease because of the low occurrence rate of adverse outcomes. The single-stage operation is safe and completion of the CEA before CPB may be considered when short duration of CPB is required.
authors: Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey. yucelozen74@yahoo.com.
authors: Y
authors: Y
authors: Ozen
authors: Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey.
authors: E
authors: E
authors: Aksoy
authors: Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey.
authors: S
authors: S
authors: Sarikaya
authors: Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey.
authors: E
authors: E
authors: Aydin
authors: Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey.
authors: O
authors: O
authors: Altas
authors: Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey.
authors: M B
authors: MB
authors: Rabus
authors: Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey.
authors: K
authors: K
authors: Kirali
mesh_terms: D000368:Aged; D016893:Carotid Stenosis / Q000150:complications / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000401:mortality; D003324:Coronary Artery Disease / Q000150:complications / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D016894:Endarterectomy, Carotid / Q000009:adverse effects / Q000401:mortality; D005260:Female; D006801:Humans; D007036:Hypothermia, Induced / Q000009:adverse effects / Q000401:mortality; D002546:Ischemic Attack, Transient / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000209:etiology; D013997:Time Factors; D016896:Treatment Outcome; D014421:Turkey
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