title: Adipose tissue: ILC2 crank up the heat.
abstract: White-to-beige conversion of adipocytes is one of the most promising approaches to therapeutically target obesity; however, the signals driving this process had largely remained unclear. Recently, two publications, Brestoff et al. (2014) in Nature and Lee et al. (2015) in Cell, showed that group 2 innate lymphoid cells directly regulate adipocyte differentiation and drive the growth of beige fat.
authors: Research Centre of Immunology and Institute of Medical Microbiology and Hygiene, University of Mainz Medical Centre, Obere Zahlbacher Strasse 67, D-55131 Mainz, Germany.
authors: Melanie
authors: M
authors: Flach
authors: Research Centre of Immunology and Institute of Medical Microbiology and Hygiene, University of Mainz Medical Centre, Obere Zahlbacher Strasse 67, D-55131 Mainz, Germany. Electronic address: diefenbach@uni-mainz.de.
authors: Andreas
authors: A
authors: Diefenbach
mesh_terms: D002001:Adipose Tissue, Brown / Q000378:metabolism*; D052436:Adipose Tissue, White / Q000166:cytology* / Q000276:immunology*; D000818:Animals; D005260:Female; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology*; D008214:Lymphocytes / Q000378:metabolism* / Q000502:physiology*; D008297:Male; D009765:Obesity / Q000276:immunology*