title: Nocardia veterana: disseminated infection with urinary tract infection.
abstract: Nocardia spp. are a group of aerobic actinomycetes widely distributed in soil, and associated with severe opportunistic infections, essentially pulmonary infections. We report the first case of disseminated infection associated with urinary tract infection caused by Nocardia veterana. The diagnosis was difficult; despite the presence of pulmonary nodules, the lung biopsies remained negative while only one aerobic blood culture and the urine culture were positive for N. veterana, identified after a 16S rDNA gene sequence analysis. Few cases of clinical importance due to N. veterana have been published since its characterization. The bacteriological diagnosis of nocardiosis can be difficult to establish because of the delayed growth and the specific techniques that are required. This case illustrates the necessity of performing specific investigations in immunocompromised patients who present with infectious disease because the severity of this infection requires early diagnosis and quick initiation of appropriate antibiotic therapy.
authors: Department of Medicine, Hospital Sainte Anne, Toulon, France.
authors: Elodie
authors: E
authors: Poisnel
authors: Department of Pneumology, Hospital Sainte Anne, Toulon, France.
authors: Jean-Baptiste
authors: JB
authors: Roseau
authors: Department of Medicine, Hospital Sainte Anne, Toulon, France.
authors: Cécile
authors: C
authors: Landais
authors: Center for Microbial Ecology, Nocardiosis French Observatory, School of Pharmacy, University Claude Bernard Lyon 1, Lyon, France.
authors: Veronica
authors: V
authors: Rodriguez-Nava
authors: Department of Nuclear Medicine, Hospital Sainte Anne, Toulon, France.
authors: Emmanuel
authors: E
authors: Bussy
authors: Department of Microbiology, Hospital Sainte Anne, Toulon, France. Electronic address: tiphaine.rousselgaillard@gmail.com.
authors: Tiphaine
authors: T
authors: Gaillard
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D009615:Nocardia / Q000235:genetics / Q000302:isolation & purification*; D009617:Nocardia Infections / Q000175:diagnosis / Q000382:microbiology*; D012336:RNA, Ribosomal, 16S; D014552:Urinary Tract Infections / Q000175:diagnosis / Q000382:microbiology*
chemical_list: D012336:RNA, Ribosomal, 16S
keywords: 16S rDNA gene sequencing; MALDI-TOF MS system; Nocardia veterana; Urinary tract infection
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