title: Study on association between lipid profile values and psychiatric disorders.
abstract: BACKGROUND
  Cholesterol is especially abundant in nervous system, where it plays important role in different aspects of cellular structure (e.g. fluidity of cell membranes) and function (e.g. membrane). Several studies showed that there may be a link between depression and low cholesterol because of altered central serotonergic functions. On the other hand, some studies also showed either no such association or yielded inconsistent results. However, many studies have related low cholesterol with different psychiatric disorders. Hence, we intend to see the possible link between the two.
  
  
  OBJECTIVE
  To study the association between lipid profile and psychiatric disorders.
  
  
  METHODS
  Patients attending Amala Institute of medical science, Psychiatry clinic in the month of January 2013 and whose lipid profile data before the start of treatment is available.
  
  
  METHODS
  Descriptive study. The patients were classified into Neurotic and Psychotic spectrum after being diagnosed with the psychiatric diseases based on International Classification of Diseases, 10(th) edition (ICD10) by a Psychiatrist. There lipid profile (Total cholesterol; LDL=Low Density Lipoprotein; HDL=High Density Lipoprotein; TAG=Triacylglycerol) were estimated before the initiation of anti-psychotic treatment.
  
  
  RESULTS
  The lipid profile values though showed some statistically significant association between the psychotic and neurotic spectrum, there was no statistical significance between the low lipid profile and different psychiatric diseases.
  
  
  CONCLUSIONS
  We have found that there is no significant association between low lipid profile and any psychiatric diseases.
authors: Associate Professor, Department of Psychiatry, Amala Institute of Medical Sciences , Thrissur, India .
authors: Shiny
authors: S
authors: John
authors: Assistant Professor, Department of Biochemistry, Amala Institute of Medical Sciences , Thrissur, India .
authors: Kavitarati
authors: K
authors: Dharwadkar
authors: Assistant Professor, Department of Anatomy, Amala Institute of Medical Sciences , Thrissur, India .
authors: Manjunath V
authors: MV
authors: Motagi
keywords: Bipolar affective disorders (BPAD); Bipolar disorders (BPD); Depression; Lipid profile; Schizophrenia
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