title: [Systematic screening of masked hypertension in patients with peripheral arterial disease: a pilot study].
abstract: OBJECTIVE
  Masked hypertension (MH) is defined by a normal office blood pressure (BP) and a high ambulatory BP. MH is characterized by high prevalence and poor cardiovascular prognosis. The aim of this study was to evaluate the usefulness of routine MH screening, using 24-h blood pressure monitoring (BPM), among patients with peripheral arterial disease (PAD).
  
  
  METHODS
  Between 2011 and 2013, 54 patients with PAD were included in the Hypertension and Vascular Medicine Unit of the Lille Hospital. They had normal office BP (< 140/90mmHg). A 24 h-BPM device was set on each patient. MH diagnosis was established if the BP average over 24 hours was ≥ 130/80 mmHg and/or the daytime average ≥ 135/85 mmHg and/or the nighttime average ≥ 120/70 mmHg.
  
  
  RESULTS
  MH prevalence was about 42.6% (23 patients). It was significantly more frequent in diabetic patients (odds ratio: 3.8 [1.1-12.8]), in patients with known hypertension (odds ratio: 5 [1.5-16.9]) or with high normal office BP (<140/90 mmHg but ≥ 130/85 mmHg) (odds ratio: 5.6 [1.7-18.2]). By multivariate analysis, only known hypertension and high normal office BP were associated with masked hypertension.
  
  
  CONCLUSIONS
  The high prevalence of MH in patients with PAD shows us the importance of a careful screening of MH in this population, especially in diabetic patients, in patients with known hypertension or with a high normal office BP.
authors: Service de médecine vasculaire et hypertension artérielle, hôpital cardiologique, CHRU de Lille, 59037 Lille, France.
authors: G
authors: G
authors: Claisse
authors: Service de médecine vasculaire et hypertension artérielle, hôpital cardiologique, CHRU de Lille, 59037 Lille, France.
authors: P
authors: P
authors: Maldonado
authors: Service de cardiologie et médecine polyvalente, centre hospitalier de Wattrelos, 59150 Wattrelos, France.
authors: N
authors: N
authors: Kpogbemabou
authors: Service de médecine vasculaire et hypertension artérielle, hôpital cardiologique, CHRU de Lille, 59037 Lille, France.
authors: F
authors: F
authors: Boudghène-Stambouli
authors: Service de médecine vasculaire et hypertension artérielle, hôpital cardiologique, CHRU de Lille, 59037 Lille, France.
authors: P
authors: P
authors: Delsart
authors: Département de biostatistiques, CHRU de Lille, 59037 Lille, France.
authors: P
authors: P
authors: Devos
authors: Service de médecine vasculaire et hypertension artérielle, hôpital cardiologique, CHRU de Lille, 59037 Lille, France. Electronic address: claire.mouniervehier@chru-lille.fr.
authors: C
authors: C
authors: Mounier-Vehier
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D048909:Diabetes Complications / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000503:physiopathology; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D059468:Masked Hypertension / Q000175:diagnosis* / Q000453:epidemiology; D008403:Mass Screening; D008875:Middle Aged; D016017:Odds Ratio; D058729:Peripheral Arterial Disease / Q000150:complications* / Q000503:physiopathology*; D010865:Pilot Projects
keywords: Ambulatory blood pressure monitoring; Artériopathie oblitérante des membres inférieurs; Hypertension artérielle masquée; Masked hypertension; Mesure ambulatoire de pression artérielle; Peripheral arterial disease