title: Quantitative assessment of pupillary light reflex in normal and anesthetized dogs: a preliminary study.
abstract: The purpose of this study was to quantitatively assess the pupillary light reflex (PLR) in normal and anesthetized dogs using a pupillometer. Eleven dogs (20 eyes) of various breeds were included. PLRs were measured with a handheld pupillometer in dim light before and during anesthesia. Anesthesia was conducted with atropine, xylazine and ketamine. Parameters of pupillometry included neurological pupil index (NPi), pupil size, percent of change (%CH), latency (LAT), constriction velocity (CV), maximum constriction velocity (MCV) and dilation velocity (DV). NPi,%CH, CV and MCV were significantly decreased during anesthesia compared with the pre-anesthesia data. The results suggest that atropine-xylazine-ketamine combination anesthesia depresses the PLR. Additionally, this study demonstrates the feasibility of the use of a pupillometer in dogs.
authors: College of Veterinary Medicine, Chonbuk National University, 664-14 Duckjin-dong, Duckjin-ku, Jeonju 561-756; Ji dong Beom Animal Hospital, 266-10 Bugok-dong, Geumjeong-ku, Busan, 609-822, Republic of Korea.
authors: Jury
authors: J
authors: Kim
authors: Jiseong
authors: J
authors: Heo
authors: Dongbeom
authors: D
authors: Ji
authors: Min-Su
authors: MS
authors: Kim
mesh_terms: D000759:Adjuvants, Anesthesia / Q000008:administration & dosage / Q000494:pharmacology; D000758:Anesthesia / Q000662:veterinary*; D000778:Anesthetics, Dissociative / Q000008:administration & dosage / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000008:administration & dosage / Q000494:pharmacology*; D016022:Case-Control Studies; D004285:Dogs / Q000502:physiology*; D004359:Drug Therapy, Combination / Q000662:veterinary; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000494:pharmacology; D007649:Ketamine / Q000008:administration & dosage / Q000494:pharmacology*; D012025:Reflex, Pupillary / Q000187:drug effects* / Q000502:physiology; D014991:Xylazine / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D000759:Adjuvants, Anesthesia; D000778:Anesthetics, Dissociative; D006993:Hypnotics and Sedatives; D014991:Xylazine; D007649:Ketamine; D001285:Atropine
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