title: Effect of several intracanal medicaments on the push-out bond strength of ProRoot MTA and Biodentine.
abstract: OBJECTIVE
  To evaluate the effect of prior application of several intracanal medicaments on the push-out bond strength of ProRoot MTA and Biodentine.
  
  
  METHODS
  Sixty freshly extracted maxillary anterior teeth were sectioned below the cementoenamel junction, and the root canals instrumented using rotary files. Thereafter, a parallel post drill was used to obtain a standardized root canal dimension. The roots were randomly assigned into one of the following groups with respect to the intracanal medicament applied: group 1: calcium hydroxide (CH) powder (Merck, Darmstadt, Germany) mixed with distilled water; group 2: a mixture of metronidazole, ciprofloxacin and minocycline (triple antibiotic paste); group 3: a combination of amoxicillin and clavulanic acid (Augmentin; Champs Pharmacy, San Antonio, TX, USA); group 4: an antibiotic-corticoid compound paste (Ledermix; Riemser, Greifswald, Germany); and group 5: no medicament (control). Following removal of medicaments with instrumentation and irrigation, the roots were cut into 1-mm-thick parallel transverse sections in a coronal-to-apical direction (5 slices/tooth). Thereafter, the specimens were divided into two subgroups according to the calcium silicate cement applied (n = 30/group): (i) ProRoot MTA (Dentsply Tulsa Dental, Tulsa, OK, USA) and (ii) Biodentine (Septodont, Saint-Maur-des-Fosses, France). A push-out test was performed, and the data were analysed statistically using two-way anova and Tukey's post hoc test.
  
  
  RESULTS
  Regardless of the type of intracanal medicament used, Biodentine had significantly higher bond strength than MTA (P < 0.05). The highest push-out bond strength results were obtained in CH-treated dentine. Compared with other medicaments, this value was only significantly higher than that of Ledermix (P < 0.05). In both the MTA and Biodentine groups, pairwise comparisons between other medicaments showed similar debonding values (P > 0.05).
  
  
  CONCLUSIONS
  Biodentine had a higher bond strength to root canal dentine than ProRoot MTA. Prior CH in distilled water intracanal placement increased the dislodgment resistance of both calcium silicate cements.
authors: Department of Endodontics, Hacettepe University, Ankara, Turkey.
authors: E
authors: E
authors: Nagas
authors: Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, Ankara, Turkey.
authors: Z C
authors: ZC
authors: Cehreli
authors: Department of Endodontics, Hacettepe University, Ankara, Turkey.
authors: M O
authors: MO
authors: Uyanik
authors: Department of Biomaterials Science and Turku Clinical Biomaterials Centre - TCBC, Institute of Dentistry, University of Turku, Turku, Finland.|City of Turku Welfare Division, Oral Health Care, Turku, Finland.
authors: P K
authors: PK
authors: Vallittu
authors: Department of Biomaterials Science and Turku Clinical Biomaterials Centre - TCBC, Institute of Dentistry, University of Turku, Turku, Finland.
authors: L V J
authors: LV
authors: Lassila
mesh_terms: D017607:Aluminum Compounds / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry; D017610:Calcium Compounds / Q000737:chemistry*; D002126:Calcium Hydroxide / Q000737:chemistry; D001840:Dental Bonding; D003786:Dental Pulp Cavity; D003799:Dental Stress Analysis; D004338:Drug Combinations; D006801:Humans; D066298:In Vitro Techniques; D008422:Materials Testing; D010087:Oxides / Q000737:chemistry*; D011897:Random Allocation; D012387:Root Canal Filling Materials / Q000737:chemistry*; D017640:Silicates / Q000737:chemistry*
chemical_list: D017607:Aluminum Compounds; D000900:Anti-Bacterial Agents; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; C506393:tricalcium silicate; D002126:Calcium Hydroxide
keywords: ProRoot MTA; biodentine; bond strength; intracanal medicaments