title: First evidence of Seoul hantavirus in the wild rat population in the Netherlands.
abstract: We report the first detection of Seoul hantavirus (SEOV)-specific antibodies in the wild brown rat population in the Netherlands. SEOV-reactive antibodies were found in three rats out of 16 in a repeated series of tests including immunofluorescence assay, immunoblot, and enzyme-linked immunosorbent assay. Focus reduction neutralization test confirmed the presence of SEOV-specific antibodies, and reverse-transcription polymerase chain reaction (RT-PCR) confirmed the presence of hantaviral RNA. This discovery follows the recent findings of SEOV infections in wild and pet brown rats and humans in England, Wales, France, Belgium, and Sweden, indicating an even higher importance of this hantavirus for public health in large areas of Europe.
authors: Department of Medical Biochemistry and Microbiology, Zoonosis Science Centre, Uppsala University, Uppsala, Sweden.|Public Health Agency of Sweden, Stockholm, Sweden.
authors: Jenny
authors: J
authors: Verner-Carlsson
authors: Department of Medical Biochemistry and Microbiology, Zoonosis Science Centre, Uppsala University, Uppsala, Sweden.|Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.|Centre for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden; mare.lohmus.sundstrom@ki.se.
authors: Mare
authors: M
authors: Lõhmus
authors: Department of Medical Biochemistry and Microbiology, Zoonosis Science Centre, Uppsala University, Uppsala, Sweden.
authors: Karin
authors: K
authors: Sundström
authors: Department of Medical Biochemistry and Microbiology, Zoonosis Science Centre, Uppsala University, Uppsala, Sweden.
authors: Tanja M
authors: TM
authors: Strand
authors: Symbiant Pathology Expert Centre, Alkmaar, The Netherlands.
authors: Monique
authors: M
authors: Verkerk
authors: Department of Viroscience, Erasmus MC, Rotterdam, The Netherlands.|Centre for Infectious Disease Control, Bilthoven, The Netherlands.
authors: Chantal
authors: C
authors: Reusken
authors: Department of Microbiology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
authors: Kumiko
authors: K
authors: Yoshimatsu
authors: Department of Microbiology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
authors: Jiro
authors: J
authors: Arikawa
authors: Symbiant Pathology Expert Centre, Alkmaar, The Netherlands.
authors: Frank
authors: F
authors: van de Goot
authors: Department of Medical Biochemistry and Microbiology, Zoonosis Science Centre, Uppsala University, Uppsala, Sweden.|Public Health Agency of Sweden, Stockholm, Sweden.
authors: Åke
authors: Å
authors: Lundkvist
keywords: Seoul virus; hantavirus; rodent-borne diseases; wildlife diseases
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