title: Bone mineral density in juvenile onset systemic lupus erythematosus.
abstract: OBJECTIVE
  To compare bone mineral density in patients with juvenile-onset Systemic lupus erythematosus and healthy controls.
  
  
  METHODS
  Serial bone mineral density measurements in 27 patients with juvenile-onset systemic lupus were compared to 97 healthy age-matched controls.
  
  
  RESULTS
  All patients with juvenile-onset had low bone mineral density scores at initial assessment that progressed over disease course. Low body mass index was independently associated with a decline in bone mineral density Z scores; disease activity, use of immunosuppressive agents and vitamin D levels were not risk factors.
  
  
  CONCLUSIONS
  Patients with juvenile-onset systemic lupus erythematosus have low bone mineral density.
authors: Departments of Child Health, *Radiology and #Pharmacology and Clinical Pharmacy, Sultan Qaboos University Hospital, Muscat, Oman. Correspondence to: Dr Reem Abdwani, Senior Consultant Pediatric Rheumatologist, Sultan Qaboos University Hospital, Muscat, Oman. reemabd@hotmail.com.
authors: R
authors: R
authors: Abdwani
authors: E
authors: E
authors: Abdulla
authors: S
authors: S
authors: Yaroubi
authors: H
authors: H
authors: Bererhi
authors: I
authors: I
authors: Al-Zakwani
mesh_terms: D000293:Adolescent; D015519:Bone Density / Q000502:physiology*; D001851:Bone Diseases, Metabolic / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology*; D008297:Male; D009850:Oman / Q000453:epidemiology; D014807:Vitamin D / Q000097:blood
chemical_list: D014807:Vitamin D