title: Transnodal lymphangiography and post-CT for protein-losing enteropathy in Noonan syndrome.
abstract: Noonan syndrome, which is a multiple congenital disorder, may be associated with lymphatic abnormalities. Protein-losing enteropathy (PLE) developing in Noonan syndrome is rare. We performed transnodal lymphangiography by directly accessing bilateral inguinal nodes under ultrasound guidance in a 17-year-old female with PLE developing in Noonan syndrome to assess detailed anatomical findings regarding lymphatic vessels. There have been no reports on transnodal lymphangiography for Noonan syndrome. Post-lymphangiographic CT images revealed multiple lymphatic abnormalities and lipiodol extravasation into the duodenum and the proximal jejunum. Transnodal lymphangiography was easy and safe for PLE developing in Noonan syndrome, and post-lymphangiographic CT provided invaluable information.
authors: Department of Radiology, Tokai University Hachioji Hospital, Tokai University School of Medicine , Tokyo , Japan.
authors: Tomohiro
authors: T
authors: Matsumoto
authors: Takahiro
authors: T
authors: Kudo
authors: Jun
authors: J
authors: Endo
authors: Kazunobu
authors: K
authors: Hashida
authors: Nao
authors: N
authors: Tachibana
authors: Takatsugu
authors: T
authors: Murakoshi
authors: Terumitsu
authors: T
authors: Hasebe
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D008220:Lymphography / Q000379:methods*; D009634:Noonan Syndrome / Q000000981:diagnostic imaging*; D011504:Protein-Losing Enteropathies / Q000000981:diagnostic imaging*; D011860:Radiography, Abdominal; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D016284:Technetium Tc 99m Pentetate; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; C070561:technetium Tc 99m DTPA-galactosyl-human serum albumin; D016284:Technetium Tc 99m Pentetate
keywords: CT; Noonan syndrome; protein-losing enteropathy; transnodal lymphangiography