title: An Update on Potential Perspectives of Glucosinolates on Protection against Microbial Pathogens and Endocrine Dysfunctions in Humans.
abstract: Glucosinolates are the major bioactive secondary metabolites found in the Brassicaceae family and studied extensively in biosynthetic and application perspectives. Because of their potential applications in the welfare of plants (protection against plant pathogens) and human life (prevention of cancer and other diseases), these compounds attracted much interest in the scientific community. In this review, we presented updates on glucosinolate derivatives in protection against microbial pathogens and endocrine related diseases in human. Further, the mechanism of action of glucosinolate derivatives and the strategies to improve their efficiency through modern approaches were discussed. Finally, the genetic enrichment of their contents in plant systems has also been discussed.
authors: a Department of Molecular Biotechnology , School of Life & Environmental Sciences, Konkuk University , Seoul , Korea.
authors: Venkidasamy
authors: V
authors: Baskar
authors: a Department of Molecular Biotechnology , School of Life & Environmental Sciences, Konkuk University , Seoul , Korea.
authors: Se Won
authors: SW
authors: Park
authors: a Department of Molecular Biotechnology , School of Life & Environmental Sciences, Konkuk University , Seoul , Korea.
authors: Shivraj Hariram
authors: SH
authors: Nile
mesh_terms: D000890:Anti-Infective Agents; D016588:Anticarcinogenic Agents; D001419:Bacteria / Q000187:drug effects; D018441:Biofilms / Q000187:drug effects; D019607:Brassicaceae / Q000737:chemistry; D004700:Endocrine System Diseases / Q000517:prevention & control*; D005961:Glucosinolates / Q000494:pharmacology / Q000627:therapeutic use*; D006728:Hormones; D006801:Humans; D009369:Neoplasms / Q000209:etiology / Q000517:prevention & control; D008517:Phytotherapy; D010935:Plant Diseases / Q000517:prevention & control; D014780:Viruses / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D016588:Anticarcinogenic Agents; D005961:Glucosinolates; D006728:Hormones
keywords: Glucosinolates; brassicaceae; endocrine; pathogens; secondary metabolites