title: High postprandial triglycerides serum levels: is obesity a good predictor?
abstract: The aim of this study was to analyze the correlation between triglyceride (TG) serum levels in obese and non-obese patients in a simulated postprandial state. Both groups showed TG levels < 150 mg/dL when fasting. After 12 h fasting, the subjects ingested a lipid overload diet and blood samples were collected. The variation between fasting and the postprandial TG peak levels were analyzed. The peak of postprandial TG levels occurred 4 h after the lipid overload in both groups. When the subjects were not fasting, the majority of non-obese subjects remained within the range of normal TG values, but the values for the obese group remained elevated. There was a significant correlation between Body Mass Index (BMI) and TG at each time point until 2 h after the meal, but the data did not show a correlation after 3 h. According to the receiver-operating characteristics (ROC) curve, postprandial TG values were not a good predictor of obesity (based on BMI), but they were a predictor of non-obesity. This study reinforces the importance of measuring non-fasting TG levels in obese and non-obese subjects, because some non-obese patients probably had altered fat metabolism, indicating that this examination could be an indicator of metabolic risk.
authors: Departamento de Biologia Estrutural, Molecular e Genética, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brasil.
authors: Viviane
authors: V
authors: Nogaroto
authors: Departamento de Cirurgia, Hospital Vicentino da Sociedade Beneficente São Camilo, Ponta Grossa, PR, Brasil.
authors: Marcos R S
authors: MR
authors: Rodrigues
authors: Departamento de Biologia Estrutural, Molecular e Genética, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brasil.
authors: Marcelo R
authors: MR
authors: Vicari
authors: Departamento de Biologia Estrutural, Molecular e Genética, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brasil.
authors: Mara C
authors: MC
authors: De Almeida
authors: Departamento de Cirurgia, Hospital Vicentino da Sociedade Beneficente São Camilo, Ponta Grossa, PR, Brasil.
authors: Fábio Q
authors: FQ
authors: Milléo
authors: Departamento de Odontologia, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brasil.
authors: Fábio A
authors: FA
authors: Dos Santos
authors: Departamento de Biologia Estrutural, Molecular e Genética, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR, Brasil.
authors: Roberto F
authors: RF
authors: Artoni
mesh_terms: D000328:Adult; D015992:Body Mass Index; D005260:Female; D006801:Humans; D015228:Hypertriglyceridemia / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D050356:Lipid Metabolism / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D019518:Postprandial Period; D011237:Predictive Value of Tests; D012372:ROC Curve; D013997:Time Factors; D014280:Triglycerides / Q000097:blood*
chemical_list: D014280:Triglycerides