title: Effectiveness of Psycho-Educational Intervention in HIV Patients' Treatment.
abstract: Adherence to Highly Active Antiretroviral Therapy (HAART) is the main prognostic factor associated with HIV disease progression and death. The aim was to evaluate the effectiveness of a psycho-educational program to promote adherence to HAART in HIV patients. A longitudinal study (n = 102) over 9 months in an Infectious Diseases Hospital was carried out. Adherence to HAART was measured with standardized scales and values of viral load. Two groups were defined: adherents and non-adherents. In the latter, a psycho-educational program was implemented and 6 months later measured adherence to HAART. Knowledge about the infection, CD4 T lymphocytes and HIV-ribonucleic acid values were measured before and after this program. The sample was predominantly male (70%), heterosexual (78%), with a mean age of 49 (SD = 12.7) years, and 48% of participants were not adhering to HAART. After the program, non-adherence decreased to 21.6%. Knowledge about the infection increased from 79 to 97%. A significant increase in CD4 T lymphocytes (mean 540-580) and a decrease in viral load (mean 5411-3052) were observed, the latter of statistical significance. This program seems to be feasible and efficient, improving adherence to HAART.
authors: Hospital Joaquim Urbano (Centro Hospitalar do Porto, EPE) , Porto , Portugal.
authors: Clarisse
authors: C
authors: Ribeiro
authors: Hospital Joaquim Urbano (Centro Hospitalar do Porto, EPE) , Porto , Portugal.
authors: Rui
authors: R
authors: Sarmento E Castro
authors: Biostatistics and Medical Informatics Service and Centre for Research in Health Technologies and Information Systems (CINTESIS), Faculty of Medicine, University of Porto , Porto , Portugal.
authors: Mário
authors: M
authors: Dinis-Ribeiro
authors: Research and Education Unit on Ageing (UNIFAI) and Centre for Research in Health Technologies and Information Systems (CINTESIS), Faculty of Medicine, University of Porto , Porto , Portugal.
authors: Lia
authors: L
authors: Fernandes
keywords: AIDS; HIV; empowerment; medication adherence; psycho-educational program
references: Chem Soc Rev. 2012 Jul 7;41(13):4657-70
references: 22618809
references: AIDS Care. 2004 Feb;16(2):177-86
references: 14676024
references: AIDS Patient Care STDS. 2013 Nov;27(11):613-20
references: 24138485
references: J Infect Dis. 2008 May 15;197 Suppl 3:S272-8
references: 18447613
references: Cochrane Database Syst Rev. 2006 Jul 19;(3):CD001442
references: 16855968
references: Bull World Health Organ. 2009 Oct;87(10):754-62
references: 19876542
references: AIDS Care. 2006 Feb;18(2):93-100
references: 16338766
references: J AIDS Clin Res. 2013 Jun 29;4:218
references: 24083060
references: Assessment. 2007 Dec;14(4):408-16
references: 17986658
references: Psychol Health Med. 2011 Oct;16(5):528-47
references: 21777090
references: Lancet. 1996 Aug 10;348(9024):383-6
references: 8709739
references: J Acquir Immune Defic Syndr. 2009 Apr 15;50(5):529-36
references: 19223785
references: Curr Infect Dis Rep. 2008 Nov;10(6):515-21
references: 18945394
references: Curr Infect Dis Rep. 2009 Mar;11(2):163-9
references: 19239808
references: AIDS Care. 2013;25(9):1149-58
references: 23311323
references: AIDS. 2011 Mar 27;25(6):F7-12
references: 21412057
references: J Affect Disord. 2013 Feb 20;145(2):221-6
references: 23017542
references: HIV Clin Trials. 2000 Jul-Aug;1(1):13-9
references: 11590485
references: AIDS Patient Care STDS. 2007 Sep;21(9):667-80
references: 17919094
references: AIDS Care. 2006 Oct;18(7):830-8
references: 16971295
references: J Infect Dis. 1995 Mar;171(3):537-45
references: 7533197
references: Psychosom Med. 2008 Jun;70(5):546-54
references: 18541905
references: Clin Infect Dis. 2008 May 15;46(10):1589-97
references: 18419495
references: Ann Intern Med. 2007 Apr 17;146(8):564-73
references: 17438315
references: Behav Res Ther. 2001 Oct;39(10):1151-62
references: 11579986
references: AIDS Care. 2011 Dec;23(12):1660-7
references: 21732897
references: AIDS Patient Care STDS. 2004 Nov;18(11):644-57
references: 15633262
references: J Acquir Immune Defic Syndr. 2006 Sep;43(1):27-34
references: 16878047
references: AIDS Patient Care STDS. 2012 Dec;26(12):718-29
references: 23199190
references: AIDS. 2011 Apr 24;25(7):905-10
references: 21399479
references: HIV Med. 2011 Oct;12(9):525-34
references: 21518221
references: Psychol Health Med. 2007 Mar;12(2):225-35; quiz 235-7
references: 17365902
references: Acta Psychiatr Scand. 1983 Jun;67(6):361-70
references: 6880820
references: AIDS Patient Care STDS. 2008 Jan;22(1):71-80
references: 18095837
references: AIDS. 2012 Jul 17;26(11):1415-23
references: 22767342
references: J Acquir Immune Defic Syndr. 2002 Dec 15;31 Suppl 3:S123-7
references: 12562034
references: AIDS Care. 2006 Aug;18(6):529-36
references: 16831778
references: Psychol Health Med. 2011 Oct;16(5):588-611
references: 21745024
references: Int J Nurs Stud. 2014 Aug;51(8):1171-89
references: 24602830
references: Lancet Infect Dis. 2011 Dec;11(12):942-51
references: 22030332
references: Presse Med. 2006 Sep;35(9 Pt 1):1241-8
references: 16969312
references: Braz J Infect Dis. 2005 Dec;9(6):494-9
references: 16410944
references: J Antimicrob Chemother. 2005 Apr;55(4):413-6
references: 15722389
references: Infect Dis Rep. 2013 Jun 06;5(Suppl 1):e2
references: 24470966
references: Am Clin Lab. 2000 May;19(4):20-2
references: 10947316
references: Ann Intern Med. 2000 Jul 4;133(1):21-30
references: 10877736
references: Int J STD AIDS. 2000 Nov;11(11):734-42
references: 11089788
references: Psychosom Med. 2008 Jun;70(5):531-8
references: 18541904
references: AIDS Patient Care STDS. 2003 Apr;17(4):169-77
references: 12737640
references: AIDS Res Treat. 2012;2012:940580
references: 23019521
references: J Infect Dis. 2005 Feb 1;191(3):339-47
references: 15633092
references: J Psychosom Res. 2003 Mar;54(3):199-203
references: 12614829
references: Haemophilia. 2013 Jan;19(1):141-9
references: 22830609
references: Curr HIV Res. 2004 Jul;2(3):207-14
references: 15279584
references: Lancet. 2005 Jul 30-Aug 5;366(9483):378-84
references: 16054937
references: Farm Hosp. 2006 May-Jun;30(3):171-6
references: 16999564
references: AIDS Patient Care STDS. 2012 Apr;26(4):234-40
references: 22364209