title: Gender disparity in the use of drug-eluting stents during percutaneous coronary intervention for acute myocardial infarction.
abstract: OBJECTIVE
  We examined gender disparity in the use of drug-eluting stents (DES) versus bare metal stents (BMS) during percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI), and gender disparity in all-cause mortality after coronary stent implantation for AMI.
  
  
  BACKGROUND
  Gender disparities in AMI managements have been well documented, but it is unclear whether these disparities are seen in the type of coronary stent implantation for AMI and outcomes.
  
  
  METHODS
  Hospital discharge data from January 1, 2003 through December 31, 2010 in New Jersey from the Myocardial Infarction Data Acquisition System were used to identify 40,215 patients (12,878 women and 27,337 men) with coronary stent implantation for AMI. The in-hospital, short term (30 days) and long term (1 and 5 year) all-cause mortality rates, unadjusted and adjusted for demographics and comorbidities, were determined.
  
  
  RESULTS
  Women were older than men and had a higher prevalence of co-morbidities. Men had higher prevalence of prior coronary revascularizations. After adjustment for co-morbidities, there was no significant gender difference in the use of DES versus BMS for AMI, except in 2003 and 2006 where women were found to be more likely to receive a DES versus a BMS. After adjustment, women had higher odds of in-hospital deaths but no difference in short and long-term all-cause mortality rates.
  
  
  CONCLUSIONS
  There was no significant gender difference in the proportion of DES implantation versus BMS for AMI in contemporary years. Women treated with either BMS or DES for AMI had higher in-hospital death than men.
authors: The Cardiovascular Institute at Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
authors: Adeyemi
authors: A
authors: Iyanoye
authors: The Cardiovascular Institute at Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
authors: Abel E
authors: AE
authors: Moreyra
authors: The Cardiovascular Institute at Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
authors: Joel N
authors: JN
authors: Swerdel
authors: Sanofi Aventis Global Pharmacovigilance and Epidemiology, Bridgewater, New Jersey.
authors: Sampada K
authors: SK
authors: Gandhi
authors: The Cardiovascular Institute at Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
authors: Javier
authors: J
authors: Cabrera
authors: The Cardiovascular Institute at Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
authors: Nora M
authors: NM
authors: Cosgrove
authors: The Cardiovascular Institute at Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
authors: John B
authors: JB
authors: Kostis
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D015897:Comorbidity; D016208:Databases, Factual; D054855:Drug-Eluting Stents / Q000706:statistics & numerical data*; D005260:Female; D054625:Healthcare Disparities; D017052:Hospital Mortality; D006801:Humans; D016015:Logistic Models; D008297:Male; D008670:Metals; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D009515:New Jersey; D016017:Odds Ratio; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000295:instrumentation* / Q000401:mortality / Q000706:statistics & numerical data*; D015995:Prevalence; D016016:Proportional Hazards Models; D011474:Prosthesis Design; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D015607:Stents / Q000706:statistics & numerical data*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D008670:Metals
keywords: acute myocardial infarction; differences; drug-eluting stents; gender; management; mortality; sex