title: Foldecture as a core material with anisotropic surface characteristics.
abstract: The synthesis of microscale, polyhedrally shaped, soft materials with anisotropic surface functionality by a bottom-up approach remains a significant challenge. Herein we report a microscale molecular architecture (foldecture) with facet-dependent surface characteristics that can potentially serve as a well-defined catalytic template. Rhombic rod shaped foldectures with six facets were obtained by the aqueous self-assembly of helical β-peptide foldamers with a C-terminal carboxylic acid. An analysis of the molecular packing by X-ray diffraction revealed that carboxylic acid groups were exposed exclusively on the two (001) rhombic facets due to antiparallel packing of the helical peptides. A surface energy calculation by molecular dynamics simulation was performed to provide a plausible explanation for the development of anisotropy during foldecture formation. The expected facet-selective surface properties of the foldecture were experimentally confirmed by selective deposition of metal nanoparticles on the (001) facets, leading to a new class of sequentially constructed, heterogeneous "foldecture core" materials.
authors: Molecular-Level Interface Research Center, Department of Chemistry, ‡Graduate School of EEWS, and §Department of Chemistry, KAIST , Daejeon 305-701, Korea.
authors: Sung Hyun
authors: SH
authors: Yoo
authors: Taedaehyeong
authors: T
authors: Eom
authors: Sunbum
authors: S
authors: Kwon
authors: Jintaek
authors: J
authors: Gong
authors: Jin
authors: J
authors: Kim
authors: Sung June
authors: SJ
authors: Cho
authors: Russell W
authors: RW
authors: Driver
authors: Yunho
authors: Y
authors: Lee
authors: Hyungjun
authors: H
authors: Kim
authors: Hee-Seung
authors: HS
authors: Lee
mesh_terms: D018360:Crystallography, X-Ray; D011487:Protein Conformation; D013499:Surface Properties