title: Correlation between high-sensitivity C reactive protein and local arterial stiffness measured by radio frequency echotracking system in type 2 diabetic patients.
abstract: OBJECTIVE
  To identify the correlation between hsCRP and arterial stiffness in type-2 diabetic patients.
  
  
  METHODS
  A cross-sectional study was conducted to assess the plasma levels of hsCRP and carotid arterial stiffness in 40 patients with type-2 diabetes mellitus. The common carotid artery stiffness was evaluated using radio frequency echo-tracking system to determine the local carotid pulse wave velocity (carotid-PWV).
  
  
  RESULTS
  Median value of hsCRP in this study was 4.5 (0.2 to 18.9) mg/L and the average value of local carotid stiffness was 8.8±1.7 m/sec. High sensitive CRP showed a strong correlation with carotid-PWV (r=0.503, P=0.001). hsCRP level was independently associated with carotid-PWV after adjustment for age, body mass index, and mean arterial pressure (r=0.450, P=0.005).
  
  
  CONCLUSIONS
  Hs-CRP has moderate positive correlation with arterial stiffness in patients with type-2 diabets mellitus.
authors: Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
authors: Azri
authors: A
authors: Nurizal
authors: Dono
authors: D
authors: Antono
authors: Ika Prasetya
authors: IP
authors: Wijaya
authors: Hamzah
authors: H
authors: Shatri
mesh_terms: D000328:Adult; D000367:Age Factors; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000032:analysis*; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D063177:Pulse Wave Analysis; D014463:Ultrasonography; D059289:Vascular Stiffness / Q000502:physiology*
chemical_list: D002097:C-Reactive Protein