title: Intradural solitary fibrous tumor of the lumbar spine: a distinctive case report.
abstract: Background. Solitary fibrous tumors are ubiquitous mesenchymal neoplasms of putative fibroblastic origin. They were originally described in the pleura but subsequently have been reported in many extraserosal sites. Solitary fibrous tumors may also occur in the meninges, central nervous system parenchyma, and spinal cord. Case. A 67-year-old male patient with progressive lower extremity weakness, urinary urgency, and sexual dysfunction has been admitted to our hospital. On his lumbar MRI, we detected an intradural lesion posterior to the L3 vertebral corpus. We resected the lesion by L3 total laminectomy. Immunohistological findings revealed strong and diffuse immunopositivity with vimentin, CD34, and bcl-2. Ki-67 proliferation index was 5-8%. We did not detect any recurrence 12 months after his operation. Conclusion. SFT is mostly seen in young and middle-aged patients and should be considered among differential diagnosis in cases suffering from pain, hypoesthesia, and urinary dysfunction. Gross total resection should be primary treatment. Tumors that have high Ki-67 labeling should be followed up for potential recurrences.
authors: Neurosurgery Department, Dr. Lutfi Kirdar Kartal Training and Research Hospital, 34890 Istanbul, Turkey.
authors: Recep
authors: 0000-0001-5186-1116
authors: R
authors: Basaran
authors: Neurosurgery Department, Eyub State Hospital, 34050 Istanbul, Turkey.
authors: Mustafa
authors: M
authors: Kaksi
authors: Neurosurgery Department, Medipol University School of Medicine, 34200 Istanbul, Turkey.
authors: Mustafa
authors: M
authors: Onoz
authors: Neurology Department, Istanbul Medeniyet University Goztepe Education and Research Hospital, 34730 Istanbul, Turkey.
authors: Ece
authors: 0000-0002-7955-5038
authors: E
authors: Balkuv
authors: Pathology Department, Acibadem University School of Medicine, 34718 Istanbul, Turkey.
authors: Aydin
authors: A
authors: Sav
references: J Surg Oncol. 2006 Jul 1;94(1):40-4
references: 16788942
references: Thorac Cardiovasc Surg. 2008 Aug;56(5):291-7
references: 18615377
references: Am J Surg Pathol. 1989 Aug;13(8):640-58
references: 2665534
references: J Clin Neurosci. 2005 Sep;12(7):829-32
references: 16169731
references: Spine (Phila Pa 1976). 2000 Mar 15;25(6):749-51
references: 10752111
references: Virchows Arch. 2002 Mar;440(3):249-60
references: 11889594
references: Arch Pathol Lab Med. 2004 Mar;128(3):335-7
references: 14987150
references: Histopathology. 1997 Dec;31(6):568-76
references: 9447390
references: Am J Clin Pathol. 1996 Aug;106(2):217-24
references: 8712177
references: J Clin Neurosci. 2009 Dec;16(12 ):1578-81
references: 19793658
references: Am J Surg Pathol. 1997 Nov;21(11):1354-60
references: 9351573
references: Spinal Cord. 2001 Jan;39(1):57-60
references: 11224018
references: Clin Neurol Neurosurg. 2011 Nov;113(9):703-10
references: 21872387