title: Do ejection fraction and other gated stress rest myocardial perfusion parameters differ by age and gender?
abstract: BACKGROUND
  We have studied the end-diastolic volume (EDV), the end-systolic volume (ESV), and the ejection fraction (EF) for patients who had normal results on treadmill exercise tests and perfusion scans. We also studied normal wall motion as diagnosed by gated myocardial perfusion imaging with the quantitative gated single photon emission tomography (QGSPECT) software set to launch a range of normal values. In addition, we evaluated differences based on age and gender.
  
  
  METHODS
  All subjects with normal results on Bruce exercise and myocardial perfusion imaging QGSPECT using the 2-days stress-rest technetium-99m (99mTc) sestamibi protocol were enrolled in the study. The quantitated functional data of EDV, ESV, and EF using the QGSPECT software were assessed in the rest and stress studies. The association of quantitated functional data with age and sex at both stress and rest was studied in 78 subjects with no symptoms from the cardiovascular system and normal QGSPECT imaging, 29 males (mean age: 58.41 ± 9.0 years) and 49 females (mean age: 58.18 ± 9.0 years). Also studied were differences between males and females.
  
  
  RESULTS
  Our results showed that in women compared with men only stress EF showed a significantly higher value (P = 0.02), whereas all other parameters including REF, SESV, SEDV, RESV, and REDV did not demonstrate a significant difference between men and women (P value > 0.05).
  
  
  CONCLUSIONS
  The study showed that EF as determined by the QGSPECT technique should be considered as gender-matched normative parameter.
authors: Masoud
authors: M
authors: Moslehi
authors: Soudabeh
authors: S
authors: Alidadi
authors: Ehsan
authors: E
authors: Assadollahi
authors: assadipoya@yahoo.com.
authors: Majid
authors: M
authors: Assadi
mesh_terms: D000375:Aging / Q000502:physiology*; D055426:Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging; D012727:Sex Characteristics; D013312:Stress, Physiological; D013318:Stroke Volume / Q000502:physiology*; D017256:Technetium Tc 99m Sestamibi
chemical_list: D017256:Technetium Tc 99m Sestamibi