title: Delayed postoperative radiation therapy in local control of squamous cell carcinoma of the tongue and floor of the mouth.
abstract: OBJECTIVE
  To evaluate the effect of time between surgery and postoperative radiation therapy on local recurrence of squamous cell carcinoma of the tongue and floor of the mouth.
  
  
  METHODS
  A total of 154 patients treated between 1996 and 2007 were selected considering local recurrence rate and time of the adjuvant radiotherapy.
  
  
  RESULTS
  Local recurrence was diagnosed in 54 (35%) patients. Radiation therapy reduced the rate of local recurrences, although with no statistical significance. The time between surgery and initiation of postoperative radiotherapy did not significantly influence the risk of local recurrence in patients referred to adjuvant treatment (p=0.49).
  
  
  CONCLUSIONS
  In the presence of risk factors for local recurrence, a short delay in starting the adjuvant radiation therapy does not contraindicate its performance.
authors: Hospital Heliópolis, Brazil.
authors: Ali
authors: A
authors: Amar
authors: Hospital Heliópolis, Brazil.
authors: Helma Maria
authors: HM
authors: Chedid
authors: Hospital Heliópolis, Brazil.
authors: Otávio Alberto
authors: OA
authors: Curioni
authors: Universidade de São Paulo, Brazil.
authors: Rogério Aparecido
authors: RA
authors: Dedivitis
authors: Hospital Heliópolis, Brazil.
authors: Abrão
authors: A
authors: Rapoport
authors: Universidade de São Paulo, Brazil.
authors: Claudio Roberto
authors: CR
authors: Cernea
authors: Universidade de São Paulo, Brazil.
authors: Lenine Garcia
authors: LG
authors: Brandão
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009060:Mouth Floor; D009062:Mouth Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control / Q000532:radiotherapy*; D011184:Postoperative Period; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant / Q000379:methods; D012307:Risk Factors; D013997:Time Factors; D014062:Tongue Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult
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