title: Subperiosteal transmission of intra-articular pressure between articulated and stationary joints.
abstract: Hydrostatic pressures can be transmitted between synovial capsules. In each of ten rabbits, we simultaneously measured pressure in two joints, one of which was passively ranged, and the other of which was kept stationary. The intra-articular pressure inside the stationary joint changed every time its companion joint was ranged. But the pressure in the stationary joint did not change when the periosteum was transected above the ranged joint. This phenomenon was observed in all four animals that served as their own controls. The study suggests that the intra-articular pressure was transmitted through the space between the periosteum and the bone surface. Alternative explanations, like measurements of venous blood pressure, did not show correlation with hydrostatic pressure changes in the joints. The Floating Skeleton concept suggests a biomechanical rationale for this newly observed phenomenon: that there exists a subperiosteal hydrostatic connection of synovial joints, and that this "net" distributes excess pressures among joints through the periosteal sheath to sustain the integrity of the joint contacting surfaces over a lifetime.
authors: Department of Physical Medicine and Rehabilitation, Tufts University School of Medicine, Boston, MA, USA.
authors: Mark
authors: M
authors: Pitkin
authors: Depatment of Orthopaedics, Tufts University School of Medicine, Boston, MA, USA.
authors: Raghuveer
authors: R
authors: Muppavarapu
authors: Depatment of Orthopaedics, Tufts University School of Medicine, Boston, MA, USA.
authors: Charles
authors: C
authors: Cassidy
authors: The Wharton School, University of Pennsylvania, Philadelphia, PA, USA.
authors: Emil
authors: E
authors: Pitkin
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001794:Blood Pressure; D006874:Hydrostatic Pressure; D007596:Joints / Q000502:physiology*; D008297:Male; D010521:Periosteum / Q000502:physiology*; D011817:Rabbits; D013582:Synovial Fluid; D013997:Time Factors
references: J Rheumatol. 1983 Jun;10(3):360-3
references: 6887160
references: Arthritis Rheum. 2004 Oct;50(10):3306-13
references: 15476254
references: Q J Exp Physiol. 1983 Oct;68(4):629-44
references: 6647739
references: Spine (Phila Pa 1976). 2011 Jul 1;36(15):1197-203
references: 21224762
references: Spine (Phila Pa 1976). 1987 Mar;12(2):105-11
references: 3589803
references: Sci Rep. 2014 Aug 29;4:6213
references: 25169063
references: Microcirculation. 1995 Sep;2(3):217-33
references: 8748946
references: J Exp Biol. 1999 Dec;202(Pt 23):3305-13
references: 10562513
references: J Glaucoma. 2000 Feb;9(1):74-82
references: 10708235
references: Ann Rheum Dis. 1997 Nov;56(11):686-9
references: 9462173
references: Skeletal Radiol. 2010 Apr;39(4):319-23
references: 20049593
references: Ann Rheum Dis. 1995 Aug;54(8):670-3
references: 7677444
references: Mech Chem Biosyst. 2004 Sep;1(3):191-9
references: 16783932
references: Ann R Coll Surg Engl. 1948 Mar;2(3):142-46
references: 18908969
references: Acta Orthop Scand. 1990 Jun;61(3):231-5
references: 2371816
references: Med Eng Phys. 2005 May;27(4):329-35
references: 15823474
references: J Physiol. 1979 Apr;289:55-67
references: 458691
references: Arch Oral Biol. 2002 Oct;47(10):733-41
references: 12356505
references: J Physiol. 1985 Mar;360:311-32
references: 3989719
references: J Arthroplasty. 2007 Jun;22(4):596-600
references: 17562419
references: J Physiol. 1984 Apr;349:27-42
references: 6737295
references: Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14819-24
references: 16203974
references: Clin Orthop Relat Res. 1995 Aug;(317):3-6
references: 7671493
references: J Biomech. 2008;41(1):128-36
references: 17697682
references: Psychometrika. 1947 Jun;12(2):153-7
references: 20254758
references: PM R. 2009 Apr;1(4):297-307
references: 19627912
references: J Anat. 1990 Aug;171:233-9
references: 2081707
references: J Orthop Surg Res. 2009 Apr 02;4:8
references: 19338673
references: J Rheumatol Suppl. 2009 Aug;83:12-3
references: 19661528
references: J Craniofac Surg. 2008 Mar;19(2):453-8
references: 18362726
references: Cell. 1996 Feb 9;84(3):381-8
references: 8608591