title: Imaging findings and clinical features of intracal lymphoplasmacyte-rich meningioma.
abstract: OBJECTIVE
  The purpose of this study was to analyze the imaging findings and clinical features of intracal lymphoplasmacyte-rich meningioma.
  
  
  METHODS
  The clinical, radiographic, and pathological data of 9 patients of lymphoplasmacyte-rich meningioma were analyzed retrospectively.
  
  
  RESULTS
  All cases were solitary; 8 patients with headache, dizziness, and vomiting; 2 patients with vision loss and one with progressive hearing loss; and 4 cases of secondary anemia, 3 of them with secondary hyperplasia of polyclonal immunoglobulin. In the plain CT scan of 6 cases, all masses showed higher density and without clear boundary, and 5 masses accompany obvious peritumoral edema. In plain MRI scan, all of the tumors appeared with irregular shape and unclear boundaries, 8 of the masses with obvious peritumoral edema. Enhanced scan showed all cases were significantly enhanced and the meninges in 7 cases thicken irregularly and extensively. The pathology showed that the tumors were irregularly shaped with grayish red or grayish white cut surfaces. Histological examination showed that the tumors consisted of abundant and diverse cells and different numbers of spindle tumor cells, and meningeal epithelial cells in the background of abundant inflammatory cells could be seen. The 9 cases all had surgery; only 1 case of recurrence in the first year after the operation was noted in the follow-up over 1 to 4 years, and no recurrence could be found after the second surgery.
  
  
  CONCLUSIONS
  Lymphoplasmacyte-rich meningioma is a seldom-seen subtype meningioma of WHO grade I, often accompanying anemia or polyclonal immunoglobulin hyperplasia, which can recover to normal state after removing the masses. The masses showed higher density and without clear boundary in plain CT scan, and most of the tumors appear with irregular shape, obvious edema, and significant enhancement in the MRI scan. The prognosis is favorable after surgical resection and the recurrence rate is low.
authors: From the Department of Radiology, The Second Hospital of Lanzhou University, Lanzhou, China.
authors: Luo
authors: L
authors: Yongjun
authors: Liu
authors: L
authors: Xin
authors: Sun
authors: S
authors: Qiu
authors: Zhou
authors: Z
authors: Jun-Lin
mesh_terms: D000293:Adolescent; D000328:Adult; D000740:Anemia / Q000175:diagnosis; D002648:Child; D004244:Dizziness / Q000175:diagnosis; D004487:Edema / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D006261:Headache / Q000175:diagnosis; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008579:Meningioma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D010950:Plasma Cells / Q000473:pathology; D012086:Reoperation; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D014839:Vomiting / Q000175:diagnosis; D055815:Young Adult