title: On-pump beating coronary artery bypass in high risk coronary patients.
abstract: BACKGROUND
  There are some conflicting results with Conventional Coronary Artery Bypass Grafts (CCABG) with arrested heart in coronary high-risk patients. Moreover, performing off-pump CABG in these cases may be associated with serious complications. The objective of this study is to evaluate the efficacy of the on-pump beating CABG (OPBCABG) in coronary high-risk patients in comparison with the conventional methods.
  
  
  METHODS
  In a prospective research study, 3000 off-pump CABG patients were considered during June 2003 to December 2011. Among these, 157 patients with one or more of the following risk factors were included for OPBCABG; severe left main stenosis, early post-acute myocardial infarction with ongoing chest pain, unstable angina, intractable ventricular arrhythmia, post complicated coronary intervention and severe left ventricular dysfunction. These patients were compared with 157 similar patients undergone CCABG with aortic cross clamp before 2003.
  
  
  RESULTS
  Preoperative patient characteristics revealed no significant differences between the two groups. The patients' mean age and number of grafts were 57 years and 3 per patient respectively. Hospital mortality was 3.2% and 9% in OPBCABG and CCABG groups, respectively (P<0.001). Preoperative myocardial infarction, requirement of inotropic agents and intraaortic balloon pump, renal dysfunction and prolonged ventilation time were significantly higher in CCABG group.
  
  
  CONCLUSIONS
  Our results suggest that OPBCABG is effective in coronary high-risk patients and significantly reduces mortality and the incidence of perioperative MI and other major complications.
authors: Department of Cardiac Surgery, Madani Heart Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
authors: Abbas
authors: A
authors: Afrasiabirad
authors: Department of Cardiac Surgery, Madani Heart Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
authors: Naser
authors: N
authors: Safaie
authors: Department of Cardiac Surgery, Madani Heart Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
authors: Hosein
authors: H
authors: Montazergaem
keywords: Cardio pulmonary bypass; Efficacy; Off pump coronary artery bypass
references: Ann Thorac Surg. 2002 Jul;74(1):115-8
references: 12118740
references: Ann Thorac Surg. 2004 Nov;78(5):1604-9
references: 15511441
references: J Card Surg. 2001 Mar-Apr;16(2):132-9
references: 11766831
references: J Thorac Cardiovasc Surg. 2004 Jun;127(6):1624-31
references: 15173716
references: Nephrol Dial Transplant. 2012 May;27(5):2059-65
references: 21956251
references: J Thorac Cardiovasc Surg. 2008 Mar;135(3):521-6
references: 18329463
references: Ann Thorac Surg. 2007 Apr;83(4):1368-73
references: 17383341
references: Ann Thorac Surg. 2006 Feb;81(2):573-6
references: 16427854
references: Heart Surg Forum. 2003;6(6):E89-92
references: 14721990
references: Lancet. 2002 Apr 6;359(9313):1194-9
references: 11955537
references: Heart Surg Forum. 2004 Jan 1;7(1):8-15
references: 14980839
references: FASEB J. 2003 Jun;17(9):1105-7
references: 12709407
references: Ren Fail. 2005;27(2):183-8
references: 15807183
references: Heart Surg Forum. 2005;8(3):E178-82; discussion E183
references: 15937002
references: Jpn J Thorac Cardiovasc Surg. 2003 May;51(5):173-7
references: 12776947
references: Eur J Cardiothorac Surg. 2001 Mar;19(3):245-8
references: 11251260