title: Superficial tunica albuginea rupture as initial starting point of Peyronie's disease: a topic for interdisciplinary consideration.
abstract: Peyronie's disease is a connective tissue disorder in the soft tissue of the penis. The underlying cause of Peyronie's disease is not well understood but is thought to be caused by trauma or injury to the penis during sexual intercourse. The purpose of the interdisciplinary cooperation between urological surgery and physics is the development of a physical simulation tool in order to give prognosis of possible tunica albuginea fibre rupture at a certain degree of deviation of the penis. For our group the first challenge was to translate the human organ of the penis into a physical model. Starting and marginal parameters had to be defined, whereby some of them had to be based on assumption, as physical data of the human living tissue have rarely been measured up to now. The algorithm and its dependencies had to be developed. This paper is a first step of a three-dimensional mathematical-physical simulation with the assumption of a 100% filled rigid penis. The calculation gives proof of the hypothesis that the fibre-load-angle of the penis is less than 12 degrees. Thus physical simulation is able to provide the surgeon with a simple instrument to calculate and forecast the risk of the individual patient.
authors: Department of Urology, Vienna International Medical Clinic, Antonigaße 97/6, 1170 Vienna, Austria.
authors: Ralf
authors: 0000-0002-9879-6742
authors: R
authors: Herwig
authors: International Study Group on Self-Organisation, Morizgasse 4, 1060 Vienna, Austria.
authors: Manfred
authors: M
authors: Bayerl
mesh_terms: D001696:Biomechanical Phenomena; D003198:Computer Simulation; D006801:Humans; D008297:Male; D008954:Models, Biological; D010411:Penile Induration / Q000503:physiopathology*; D010413:Penis / Q000503:physiopathology*
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