title: Fenestrations of intracranial arteries.
abstract: OBJECTIVE
  Few data are available on the frequency and location distribution of fenestrations of intracranial arteries. We used 3D rotational angiography of all intracranial arteries in a cohort of 179 patients with suspected intracranial aneurysms to assess the prevalence and location of fenestrations and the relation of fenestrations to aneurysms.
  
  
  METHODS
  Of 179 patients with subarachnoid hemorrhage admitted between March 2013 and June 2014, 140 had 3D rotational angiography of all cerebral vessels. The presence and location of aneurysms and fenestrations were assessed. In patients with both aneurysms and fenestrations, we classified the relation of the location of the aneurysm as remote from the fenestration or on the fenestration.
  
  
  RESULTS
  In 140 patients, 210 aneurysms were present. In 33 of 140 patients (24%; 95% confidence interval, 17.2%-31.3%), 45 fenestrations were detected with the following locations: anterior communicating artery in 31 (69%), A1 segment of the anterior cerebral artery in 4 (9%), middle cerebral artery in 4 (9%), basilar artery in 4 (9%), vertebral artery in 1 (2%), and anterior inferior cerebellar artery in 1 (2%). Of 56 patients with anterior communicating artery aneurysms, 14 had a fenestration on the anterior communicating artery complex. The remaining 31 fenestrations had no anatomic relation to aneurysms. In 140 patients with 210 aneurysms, 14 aneurysms (7%) were located on a fenestration and 196 were not.
  
  
  CONCLUSIONS
  In patients with a suspected ruptured aneurysm, fenestrations of intracranial arteries were detected in 24% (33 of 140). Most fenestrations were located on the anterior communicating artery. Of 45 fenestrations, 14 (31%) were related to an aneurysm.
authors: From the Department of Radiology (S.B.T.v.R.), Medisch Centrum Alkmaar, Alkmaar, the Netherlands.
authors: S B T
authors: SB
authors: van Rooij
authors: Department of Radiology (R.S.B., J.P.P., M.S., W.J.v.R.), St. Elisabeth Ziekenhuis, Tilburg, the Netherlands.
authors: R S
authors: RS
authors: Bechan
authors: Department of Radiology (R.S.B., J.P.P., M.S., W.J.v.R.), St. Elisabeth Ziekenhuis, Tilburg, the Netherlands.
authors: J P
authors: JP
authors: Peluso
authors: Department of Radiology (R.S.B., J.P.P., M.S., W.J.v.R.), St. Elisabeth Ziekenhuis, Tilburg, the Netherlands.
authors: M
authors: M
authors: Sluzewski
authors: Department of Radiology (R.S.B., J.P.P., M.S., W.J.v.R.), St. Elisabeth Ziekenhuis, Tilburg, the Netherlands. wjjvanrooij@gmail.com.
authors: W J
authors: WJ
authors: van Rooij
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging*; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D005260:Female; D006760:Hospitalization; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
references: Surg Radiol Anat. 2008 Jul;30(5):397-401
references: 18350245
references: J Clin Neurosci. 2014 Dec;21(12):2184-8
references: 25150765
references: Semin Ultrasound CT MR. 2011 Jun;32(3):242-51
references: 21596279
references: AJNR Am J Neuroradiol. 1993 May-Jun;14(3):675-80
references: 8517358
references: Interv Neuroradiol. 2013 Dec;19(4):461-5
references: 24355150
references: Interv Neuroradiol. 2006 Jan 20;12(Suppl 1):39-44
references: 20569599
references: Neurosurgery. 1997 Jun;40(6):1211-6; discussion 1216-8
references: 9179894
references: Neuroradiology. 2012 May;54(5):445-50
references: 21732084
references: Surg Neurol. 1986 Aug;26(2):129-41
references: 3726739
references: Am J Roentgenol Radium Ther Nucl Med. 1967 Sep;101(1):68-87
references: 6037344
references: Neuroradiology. 2006 Sep;48(9):647-52
references: 16786350
references: Eur J Radiol. 2011 Mar;77(3):392-6
references: 19811882
references: Interv Neuroradiol. 2014 May-Jun;20(3):261-74
references: 24976087
references: AJNR Am J Neuroradiol. 2009 Aug;30(7):1347-50
references: 19439481