title: Environmentally relevant concentrations of benzo[a]pyrene affect steroid levels and affect gonad of male scallop Chlamys farreri.
abstract: Sexually mature male Chlamys farreri were exposed to benzo[a]pyrene for 10 days at four concentrations at 0, 0.025, 0.5 and 10 μg/L. Fluctuations in sex steroids during the exposure period were observed, which indicated that sex steroids have a role in gamete development. Exposure to B[a]P altered levels of 17β-estradiol, testosterone, and progesterone. Furthermore, B[a]P treatments induced oxidative stress in a dose-dependent manner on spermary of scallop and led to delayed development and damaged spermatid in germinal epithelium of spermary. Overall, B[a]P affected the steroid levels and induced gonadal toxicity at environmentally relevant concentrations.
authors: The Key Laboratory of Mariculture, Fisheries College, Ministry of Education, Ocean University of China, Yushan Road 5, Qingdao 266003, PR China.
authors: Shuangmei
authors: S
authors: Tian
authors: The Key Laboratory of Mariculture, Fisheries College, Ministry of Education, Ocean University of China, Yushan Road 5, Qingdao 266003, PR China. Electronic address: panlq@ouc.edu.cn.
authors: Luqing
authors: L
authors: Pan
authors: The Key Laboratory of Mariculture, Fisheries College, Ministry of Education, Ocean University of China, Yushan Road 5, Qingdao 266003, PR China.
authors: Yanxia
authors: Y
authors: Tao
authors: The Key Laboratory of Mariculture, Fisheries College, Ministry of Education, Ocean University of China, Yushan Road 5, Qingdao 266003, PR China.
authors: Xiaohua
authors: X
authors: Sun
mesh_terms: D000818:Animals; D001564:Benzo(a)pyrene / Q000633:toxicity*; D004785:Environmental Pollutants / Q000633:toxicity*; D004958:Estradiol / Q000378:metabolism; D012739:Gonadal Steroid Hormones / Q000378:metabolism*; D006066:Gonads / Q000187:drug effects / Q000378:metabolism; D008297:Male; D049897:Pectinidae / Q000187:drug effects* / Q000378:metabolism; D011374:Progesterone / Q000378:metabolism; D013739:Testosterone / Q000378:metabolism
chemical_list: D004785:Environmental Pollutants; D012739:Gonadal Steroid Hormones; D001564:Benzo(a)pyrene; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol
keywords: Benzo[a]pyrene; Chlamys farreri; Reproductive toxicity; Steroids levels; Tissue lesion