title: First report of chronic pulmonary infection by KPC-3-producing and colistin-resistant Klebsiella pneumoniae sequence type 258 (ST258) in an adult patient with cystic fibrosis.
abstract: The spread of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae continues to increase, and the possible development of KPC-producing K. pneumoniae infections in cystic fibrosis (CF) patients is a matter of concern. Here, we describe the establishment of a chronic lung infection due to a colistin-resistant KPC-producing K. pneumoniae isolate in an Italian CF patient.
authors: Clinica Malattie Infettive, Università di Genova (DISSAL)-AOU IRCCS San Martino-IST, Genoa, Italy.
authors: Emanuele
authors: E
authors: Delfino
authors: Clinica Malattie Infettive, Università di Genova (DISSAL)-AOU IRCCS San Martino-IST, Genoa, Italy daniele.roberto.giacobbe@gmail.com.
authors: Daniele Roberto
authors: DR
authors: Giacobbe
authors: Clinica Malattie Infettive, Università di Genova (DISSAL)-AOU IRCCS San Martino-IST, Genoa, Italy.
authors: Valerio
authors: V
authors: Del Bono
authors: Unità Operativa di Microbiologia, Università di Genova (DISC)-AOU IRCCS San Martino-IST, Genoa, Italy.
authors: Erika
authors: E
authors: Coppo
authors: Unità Operativa di Microbiologia, Università di Genova (DISC)-AOU IRCCS San Martino-IST, Genoa, Italy.
authors: Anna
authors: A
authors: Marchese
authors: Unità Operativa di Microbiologia, Università di Genova (DISC)-AOU IRCCS San Martino-IST, Genoa, Italy.
authors: Graziana
authors: G
authors: Manno
authors: Centro Fibrosi Cistica, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
authors: Patrizia
authors: P
authors: Morelli
authors: Centro Fibrosi Cistica, IRCCS Istituto Giannina Gaslini, Genoa, Italy.
authors: Laura
authors: L
authors: Minicucci
authors: Clinica Malattie Infettive, Università di Genova (DISSAL)-AOU IRCCS San Martino-IST, Genoa, Italy.
authors: Claudio
authors: C
authors: Viscoli
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003091:Colistin / Q000494:pharmacology*; D003550:Cystic Fibrosis / Q000150:complications*; D024881:Drug Resistance, Bacterial; D006801:Humans; D007710:Klebsiella Infections / Q000150:complications / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000145:classification* / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D000066608:Underage Drinking
chemical_list: D000900:Anti-Bacterial Agents; D003091:Colistin
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