title: Management of melioidosis osteomyelitis and septic arthritis.
abstract: Little information is available about several important aspects of the treatment of melioidosis osteomyelitis and septic arthritis. We undertook a retrospective review of 50 patients with these conditions in an attempt to determine the effect of location of the disease, type of surgical intervention and duration of antibiotic treatment on outcome, particularly complications and relapse. We found that there was a 27.5% risk of osteomyelitis of the adjacent bone in patients with septic arthritis in the lower limb. Patients with septic arthritis and osteomyelitis of an adjacent bone were in hospital significantly longer (p = 0.001), needed more operations (p = 0.031) and had a significantly higher rate of complications and re-presentation (p = 0.048). More than half the patients (61%), most particularly those with multifocal bone and joint involvement, and those with septic arthritis and osteomyelitis of an adjacent bone who were treated operatively, needed more visits to theatre.
authors: Royal Darwin Hospital, 105 Rocklands Drive, Tiwi, NT 0810, Australia.
authors: R P
authors: RP
authors: Shetty
authors: The Prince Charles Hospital, Rode Road, Brisbane, QLD 4032, Australia.
authors: M
authors: M
authors: Mathew
authors: Mackay Base Hospital, 475 Bridge Rd, West Mackay, QLD 4740, Australia.
authors: J
authors: J
authors: Smith
authors: Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, Australia.
authors: L P
authors: LP
authors: Morse
authors: Royal Darwin Hospital, 105 Rocklands Drive, Tiwi, NT 0810, Australia.
authors: J A
authors: JA
authors: Mehta
authors: Royal Darwin Hospital, 105 Rocklands Drive, Tiwi, NT 0810, Australia.
authors: B J
authors: BJ
authors: Currie
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology* / Q000601:surgery*; D003131:Combined Modality Therapy; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D008554:Melioidosis / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery*; D008875:Middle Aged; D010019:Osteomyelitis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology* / Q000601:surgery*
chemical_list: D000900:Anti-Bacterial Agents
keywords: Bone and joint Melioidosis; Melioidosis; Osteomyelitis; Septic arthritis