title: Circulating biomarkers of tolerance.
abstract: On the basis of reviewed literature here we describe models of tolerance and summarize the evidence of circulating biomarkers suitable for the assessment of immunological risk in organ transplantation. We focused on results of evaluation of specific peripheral immune cell populations and transcripts in peripheral blood of operationally tolerant liver and kidney transplant recipients. Validation of described markers to define potentially tolerant patients before their use in clinical trials is critical.
authors: Transplant Laboratory, Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
authors: Eva
authors: E
authors: Girmanova
authors: Transplant Laboratory, Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
authors: Petra
authors: P
authors: Hruba
authors: Department of Nephrology, Transplant Laboratory, Transplant Center, Institute for Clinical and Experimental Medicine, Prague, Czech Republic. Electronic address: ondrej.viklicky@medicon.cz.
authors: Ondrej
authors: O
authors: Viklicky
mesh_terms: D016175:B-Lymphocyte Subsets / Q000502:physiology*; D015415:Biomarkers / Q000097:blood*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D016031:Liver Transplantation / Q000009:adverse effects*; D015166:Monitoring, Immunologic; D016176:T-Lymphocyte Subsets / Q000502:physiology*; D023001:Transplantation Tolerance / Q000502:physiology*
chemical_list: D015415:Biomarkers