title: Deep brain stimulation and responsiveness of the Persian version of Parkinson's disease questionnaire with 39-items.
abstract: BACKGROUND
  Assessment of quality-of-life (QOF) as an outcome measure after deep brain stimulation (DBS) surgery in patients with Parkinson's disease (PD) need a valid, reliable and responsive instrument. The aim of the current study was to determine responsiveness of validated Persian version of PD questionnaire with 39-items (PDQ-39) after DBS surgery in patients with PD.
  
  
  METHODS
  Eleven patients with PD, who were candidate for DBS operation between May 2012 and June 2013 were assessed. PDQ-39 and short-form questionnaire with 36-items (SF-36) were used. To assess responsiveness of PDQ-39 standardized response mean (SRM) was used.
  
  
  RESULTS
  Mean age was 51.8 (8.8) and all of the patients, but just one were male (10 patients). Mean duration of the disease was 8.7 (2.1) years. Eight patients were categorized as moderate using Hoehn and Yahr (H and Y) classification. All patients had a better H and Y score compared with the baseline evaluation (3.09 vs. 0.79). The amount of SRM was above 0.70 for all domains means a large responsiveness for PDQ-39.
  
  
  CONCLUSIONS
  Persian version of PDQ-39 has an acceptable responsiveness and could be used to assess as an outcome measure to evaluate the effect of therapies on PD.
authors: Department of Neurology, School of Medicine, Rasoule-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors: Gholam Ali
authors: GA
authors: Shahidi
authors: Department of Psychology, School of Humanities, Tarbiat-Modares University, Tehran, Iran.
authors: Zeinab
authors: Z
authors: Ghaempanah
authors: Department of Community Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
authors: Yasaman
authors: Y
authors: Khalili
authors: Department of Community Medicine, School of Medicine, Preventive Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran.
authors: Marzieh
authors: M
authors: Nojomi
keywords: Deep Brain Stimulation; Parkinson’s Disease Questionnaire with 39-Items; Responsiveness
references: Neurology. 1967 May;17(5):427-42
references: 6067254
references: J Clin Epidemiol. 2000 May;53(5):459-68
references: 10812317
references: Control Clin Trials. 1991 Aug;12(4 Suppl):142S-158S
references: 1663851
references: Age Ageing. 1995 Nov;24(6):505-9
references: 8588541
references: N Engl J Med. 1998 Oct 15;339(16):1105-11
references: 9770557
references: J Neurol Neurosurg Psychiatry. 1988 Jun;51(6):745-52
references: 2841426
references: Mov Disord. 1997 Nov;12(6):916-22
references: 9399215
references: Lancet Neurol. 2010 Jun;9(6):581-91
references: 20434403
references: Qual Life Res. 2005 Apr;14(3):875-82
references: 16022079
references: N Engl J Med. 2006 Aug 31;355(9):896-908
references: 16943402
references: J Epidemiol. 2009;19(6):281-93
references: 19801887
references: J Neurol Sci. 2006 Oct 25;248(1-2):151-7
references: 16797028
references: J Neurol Neurosurg Psychiatry. 2011 Jul;82(7):754-60
references: 19465417
references: Qual Life Res. 1995 Jun;4(3):241-8
references: 7613534
references: Mov Disord. 2000 Mar;15(2):216-23
references: 10752569
references: N Engl J Med. 2001 Sep 27;345(13):956-63
references: 11575287
references: J Res Med Sci. 2010 Mar;15(2):63-9
references: 21526061
references: JAMA. 2009 Jan 7;301(1):63-73
references: 19126811
references: Age Ageing. 2000 Jan;29(1):41-5
references: 10690694
references: Ann Neurol. 2009 May;65(5):586-95
references: 19288469
references: Mov Disord. 2002 Mar;17(2):372-7
references: 11921126
references: J Neurol Neurosurg Psychiatry. 2004 Oct;75(10):1382-5
references: 15377681
references: Neurology. 2005 Jan 25;64(2):216-23
references: 15668416
references: Neurology. 2000;54(11 Suppl 5):S21-3
references: 10854357