title: Boosting Cognition With Music in Patients With Disorders of Consciousness.
abstract: BACKGROUND
  Music listening conveys beneficial effects on cognitive processes in both normal and pathologic cerebral functioning. Surprisingly, no quantitative study has evaluated the potential effects of music on cognition and consciousness in patients with disorders of consciousness.
  
  
  OBJECTIVE
  The aim of the present study was to evaluate the effect of music on cerebral processing in patients with disorders of consciousness.
  
  
  METHODS
  Using bedside electroencephalographic recording, we acquired in 13 patients with disorders of consciousness event-related potentials to the patient's first name after either an excerpt of the patient's preferred music (music condition) or a continuous sound (control condition).
  
  
  RESULTS
  The cerebral response to the patient's first name was more often observed in the music condition, than in the control condition. Furthermore, the presence or absence of a discriminative response in the music condition seemed to be associated with a favorable or unfavorable outcome, respectively.
  
  
  CONCLUSIONS
  These findings demonstrate for the first time that music has a beneficial effect on cognitive processes of patients with disorders of consciousness. The autobiographical characteristics of music, that is, its emotional and personal relevance, probably increase arousal and/or awareness.
authors: Auditory Cognition and Psychoacoustics Team, Lyon Neuroscience Research Center (UCBL, CNRS UMR5292, Inserm U1028), Lyon, France maite.castro@inserm.fr.
authors: Maïté
authors: M
authors: Castro
authors: Auditory Cognition and Psychoacoustics Team, Lyon Neuroscience Research Center (UCBL, CNRS UMR5292, Inserm U1028), Lyon, France.
authors: Barbara
authors: B
authors: Tillmann
authors: Integrative, Multisensory, Perception, Action and Cognition Team, Lyon Neuroscience Research Center (UCBL, CNRS UMR5292, Inserm U1028), Lyon, France Department of Physical Medicine and Rehabilitation, Henry Gabrielle Hospital, Hospices Civils de Lyon, Lyon, France.
authors: Jacques
authors: J
authors: Luauté
authors: Auditory Cognition and Psychoacoustics Team, Lyon Neuroscience Research Center (UCBL, CNRS UMR5292, Inserm U1028), Lyon, France.
authors: Alexandra
authors: A
authors: Corneyllie
authors: Department of Intensive Care, Neurological Hospital, Hospices Civils de Lyon, Lyon, France.
authors: Frédéric
authors: F
authors: Dailler
authors: Clinical Neurophysiology Unit, Neurological Hospital, Hospices Civils de Lyon, Lyon, France Central Integration of Pain in Humans, Lyon Neuroscience Research Center (UCBL, CNRS UMR5292, Inserm U1028), Lyon, France.
authors: Nathalie
authors: N
authors: André-Obadia
authors: Auditory Cognition and Psychoacoustics Team, Lyon Neuroscience Research Center (UCBL, CNRS UMR5292, Inserm U1028), Lyon, France.
authors: Fabien
authors: F
authors: Perrin
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000293:Adolescent; D000328:Adult; D001307:Auditory Perception / Q000502:physiology*; D001921:Brain / Q000503:physiopathology*; D003071:Cognition / Q000502:physiology*; D003244:Consciousness Disorders / Q000503:physiopathology* / Q000534:rehabilitation*; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory; D005260:Female; D015600:Glasgow Coma Scale; D023261:Glasgow Outcome Scale; D006801:Humans; D008297:Male; D008875:Middle Aged; D009146:Music; D009147:Music Therapy / Q000379:methods*; D009275:Names; D012815:Signal Processing, Computer-Assisted; D055815:Young Adult
keywords: P3 event-related potential; auditory-evoked potentials; cognition; consciousness disorders; music