title: A cost-effective rabbit embolic stroke bioassay: insight into the development of acute ischemic stroke therapy.
authors: Departments of Neurology and Neurosurgery, Cedars-Sinai Medical Center, Advanced Health Sciences Pavilion Suite 8305, 127 S. San Vicente Blvd., Los Angeles, CA, 90048, USA, Paul.Lapchak@cshs.org.
authors: Paul A
authors: PA
authors: Lapchak
mesh_terms: D000818:Animals; D001681:Biological Assay / Q000379:methods*; D002545:Brain Ischemia / Q000150:complications; D003362:Cost-Benefit Analysis; D004195:Disease Models, Animal; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D011817:Rabbits; D020521:Stroke / Q000188:drug therapy* / Q000209:etiology; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator
references: Science. 1985 Dec 13;230(4731):1289-92
references: 3934754
references: Stroke. 2014 Nov;45(11):3175-7
references: 25293661
references: Stroke. 1992 May;23(5):767-73
references: 1579976
references: Best Pract Res Clin Anaesthesiol. 2005 Sep;19(3):461-74
references: 16013694
references: Transl Stroke Res. 2011 Jun;2(2):138-43
references: 21654913
references: Sci Transl Med. 2012 Oct 17;4(156):156ps20
references: 23076354
references: Prog Neuropsychopharmacol Biol Psychiatry. 2013 Dec 2;47:156-61
references: 23721657
references: Trends Neurosci. 1999 Sep;22(9):391-7
references: 10441299
references: Transl Stroke Res. 2014 Oct;5(5):569-76
references: 24711015
references: Cerebrovasc Brain Metab Rev. 1993 Spring;5(1):1-16
references: 8452759
references: Comp Med. 2010 Aug;60(4):256-62
references: 20819374
references: Stroke. 1988 Sep;19(9):1174-9
references: 3046074
references: Stroke. 2000 Dec;31(12):3034-40
references: 11108768
references: Expert Opin Investig Drugs. 2014 Jun;23(6):865-73
references: 24766516
references: Expert Opin Investig Drugs. 2002 Nov;11(11):1623-32
references: 12437508
references: Lancet. 2004 Mar 6;363(9411):768-74
references: 15016487
references: Stroke. 2014 Oct;45(10):3032-9
references: 25190439
references: PLoS One. 2014 Oct 20;9(10):e110525
references: 25329637
references: JAMA. 2000 Mar 1;283(9):1145-50
references: 10703776
references: Neuron. 2010 Jul 29;67(2):181-98
references: 20670828
references: Ann Emerg Med. 2013 Jan;61(1):46-55
references: 22633340
references: Ann Neurol. 2006 Mar;59(3):467-77
references: 16453316
references: Transl Stroke Res. 2013 Jun;4(3):343-50
references: 24323301
references: Expert Opin Pharmacother. 2010 Jul;11(10):1753-63
references: 20491547
references: Transl Stroke Res. 2013 Jun;4(3):322-7
references: 23730351
references: Transl Stroke Res. 2013 Jun;4(3):308-21
references: 23682299
references: Arch Neurol. 1987 Aug;44(8):848-50
references: 3632395
references: Nature. 2012 Oct 11;490(7419):187-91
references: 23060188
references: Stroke. 1994 Nov;25(11):2220-6
references: 7974549
references: Metab Brain Dis. 2015 Apr;30(2):461-7
references: 24526567
references: Transl Stroke Res. 2013 Jun;4(3):279-85
references: 23658596
references: Brain Res. 2009 Oct 19;1294:211-7
references: 19643097
references: Int J Stroke. 2012 Oct;7(7):589-96
references: 22989394
references: Stroke. 2013 Mar;44(3):841-3
references: 23391768
references: Expert Opin Emerg Drugs. 2007 Sep;12(3):389-406
references: 17874968
references: Stroke. 1990 Nov;21(11):1589-93
references: 2122552
references: J Investig Med. 2013 Oct;61(7):1078-83
references: 23884213
references: Nat Clin Pract Cardiovasc Med. 2006 Apr;3(4):184-5
references: 16568123
references: Transl Stroke Res. 2013 Feb;4(1):89-103
references: 23504609
references: N Engl J Med. 2006 Feb 9;354(6):588-600
references: 16467546
references: Stroke. 2004 Aug;35(8):1985-8
references: 15155955
references: Expert Opin Emerg Drugs. 2007 Mar;12(1):97-112
references: 17355216
references: Expert Opin Biol Ther. 2009 Jun;9(6):773-8
references: 19456211
references: Stroke. 1999 Dec;30(12):2752-8
references: 10583007
references: Exp Neurol. 2004 Aug;188(2):286-91
references: 15246828
references: Transl Stroke Res. 2014 Oct;5(5):562-8
references: 24687517
references: N Engl J Med. 1995 Dec 14;333(24):1581-7
references: 7477192
references: Lancet Neurol. 2006 Sep;5(9):722-4
references: 16914399
references: CNS Drugs. 2010 Nov;24(11):893-907
references: 20932063
references: Expert Opin Biol Ther. 2013 Mar;13(3):447-53
references: 23394378
references: Curr Opin Anaesthesiol. 2007 Oct;20(5):395-9
references: 17873591
references: Transl Stroke Res. 2013 Jun;4(3):297-307
references: 24323300
references: Curr Neurol Neurosci Rep. 2002 Jan;2(1):38-43
references: 11898581
references: Transl Stroke Res. 2010 Jun;1(2):96-107
references: 20539748
references: Altern Lab Anim. 2013 Nov;41(5):385-415
references: 24329746
references: J Pharmacol Exp Ther. 1972 Dec;183(3):577-607
references: 4636393
references: Stroke. 2008 Jun;39(6):1751-8
references: 18369171
references: Transl Stroke Res. 2014 Oct;5(5):535-7
references: 25053258
references: Stroke. 2000 Aug;31(8):1953-6; discussion 1957
references: 10926963
references: Transl Stroke Res. 2013 Jun;4(3):328-42
references: 23687519
references: Transl Stroke Res. 2014 Dec;5(6):692-700
references: 25043802
references: Lancet. 1998 Oct 17;352(9136):1245-51
references: 9788453
references: Exp Neurol. 2004 Jan;185(1):154-9
references: 14697326
references: Stroke. 2014 Nov;45(11):3187-93
references: 25293665
references: Neurology. 1989 May;39(5):703-8
references: 2496332
references: Stroke. 2014 Mar;45(3):896-9
references: 24473182
references: J Anesth. 2005;19(2):150-6
references: 15875133