title: Comparative evaluation of Comfilcon A and Senofilcon A bandage contact lenses after transepithelial photorefractive keratectomy.
abstract: OBJECTIVE
  To evaluate and compare Comfilcon A and Senofilcon A silicone hydrogel contact lenses used as a therapeutic bandage following transepithelial excimer laser photorefractive keratectomy (PRK).
  
  
  METHODS
  Patients undergoing transepithelial PRK for myopia were prospectively recruited. Included patients had a Comfilcon A silicone hydrogel lens inserted in one eye, with a Senofilcon A lens in the contralateral eye. Postoperative assessment of subjective pain, epithelial healing and visual recovery was at day 1, 3 and 7. Contact lens factors including centration, movement and deposits were assessed.
  
  
  RESULTS
  48 eyes of 24 patients were included in the study. Mean age was 31 years (SD 11) and mean refractive error -4.5 D (SD 1.8). Mean pain score at day 1 was significantly higher in the Comfilcon group at 4.6 (SD 2.7) vs. 1.5 (SD2.5) in the Senofilcon group (P<0.005). Mean time to healing was 3.17 days (SD 0.37) in the Comfilcon group, and 3.21 days (SD 0.4) in the Senofilcon group, with no difference in defect size. There was a pronounced central raphe in 1 eye in the Comfilcon group vs. 5 eyes in the Senofilcon group (P=0.19). Significantly more eyes demonstrated no lens movement in the Senofilcon group (18 vs. 4, P=0.0001).
  
  
  CONCLUSIONS
  The variation in material characteristics and lens geometry of different silicone hydrogel lenses affects their clinical characteristics in therapeutic roles. Other factors than oxygen permeability may affect pain and epithelial healing, with superior pain relief from the less permeable Senofilcon lens in this study.
authors: Emmetropia Mediterranean Eye Clinic, Crete, Greece. Electronic address: hatch.mukherjee@gmail.com.
authors: Achyut
authors: A
authors: Mukherjee
authors: Emmetropia Mediterranean Eye Clinic, Crete, Greece.
authors: Antonis
authors: A
authors: Ioannides
authors: Emmetropia Mediterranean Eye Clinic, Crete, Greece.
authors: Ioannis
authors: I
authors: Aslanides
mesh_terms: D000328:Adult; D047070:Bandages, Hydrocolloid; D003263:Contact Lenses, Hydrophilic; D058447:Eye Pain / Q000628:therapy*; D005260:Female; D006801:Humans; D020100:Hydrogels / Q000627:therapeutic use*; D008297:Male; D009216:Myopia / Q000601:surgery; D010149:Postoperative Pain / Q000628:therapy*; D018903:Photorefractive Keratectomy / Q000379:methods; D011446:Prospective Studies; D012828:Silicones / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D020100:Hydrogels; D012828:Silicones; C540498:comfilcon A; C523196:senofilcon A
keywords: Bandage contact lens; Lentes de contacto como apósito; Lentes de contacto de hidrogel de silicona; PRK transepitelial; Photorefractive keratectomy; Queratectomía fotorrefractiva; Silicone hydrogel contact lens; Transepithelial PRK
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