title: A study on the cervical spondylotic myelopathy treated by anterior cervical diskectomy and fusion in accordance with Modic changes with a 2-year minimum follow-up.
abstract: BACKGROUND
  The aim of this research is to analyze the influence of Modic types on the clinical results of cervical spondylotic myelopathy treated by anterior cervical diskectomy and fusion.
  
  
  METHODS
  A total of 106 patients with a mean age of 55.8 ± 6.5 years were included in this study. Patients with Modic changes were retrospectively reviewed. In this study, 23 patients were classified as Modic-1, 39 patients were classified as Modic-2, and 44 patients were classified as Modic-0. Clinical evaluations were performed preoperatively and repeated at 3, 6, 12, and 24 months after operation.
  
  
  RESULTS
  In this study, all patients were followed up for a mean period of 30.2 months (range, from 24 to 36 months). Significant clinical improvement (P < 0.05) was observed in Japanese Orthopaedic Association (JOA) score and axial symptoms between the preoperative evaluation and the final follow-up. Comparing the result of mean JOA score after anterior cervical diskectomy and fusion (ACDF) in the Modic-1 group and other groups, statistically significant differences could be found at 12 months after surgery (P < 0.05). Comparing the outcome visual analog scale (VAS) of axial symptoms among different groups after ACDF, patients with Modic-1 changes showed significantly lower VAS of axial symptoms postoperatively (P < 0.05).
  
  
  CONCLUSIONS
  After anterior cervical diskectomy and fusion, both Modic-1 and Modic-2 groups showed excellent clinical outcomes over a 2-year follow-up. Better clinical results were achieved in patients with Modic-1 changes compared to the group of patients with Modic-2 and Modic-0 changes on magnetic resonance images.
authors: Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, The Key Laboratory of Orthopedic Biomechanics of Hebei Province, 139 Ziqiang Road, Shijiazhuang, 050051, China. ljlyqbwin2010@126.com.
authors: Jia
authors: J
authors: Li
authors: Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, The Key Laboratory of Orthopedic Biomechanics of Hebei Province, 139 Ziqiang Road, Shijiazhuang, 050051, China. lyqxueku@sina.com.
authors: Yongqian
authors: Y
authors: Li
authors: Department of Orthopedic Surgery, Hebei General Hospital, 348 Heping Road, Shijiazhuang, 050000, China. drweijingchao@126.com.
authors: Jingchao
authors: J
authors: Wei
authors: Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, The Key Laboratory of Orthopedic Biomechanics of Hebei Province, 139 Ziqiang Road, Shijiazhuang, 050051, China. docshenyong@163.com.
authors: Yong
authors: Y
authors: Shen
mesh_terms: D000328:Adult; D000368:Aged; D002574:Cervical Vertebrae / Q000473:pathology / Q000601:surgery*; D017586:Diskectomy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013117:Spinal Cord Compression / Q000209:etiology* / Q000473:pathology / Q000601:surgery*; D013123:Spinal Fusion; D055009:Spondylosis / Q000150:complications / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome
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