title: Evaluation of the effectiveness of a hyperoxidized oil-based medication in the treatment of skin lesions: observational study.
abstract: OBJECTIVE
  Aim of the study was to demonstrate the effectiveness, in the management of recalcitrant wounds, of a hyperoxidized oil-based gel with film-forming and protective functions.
  
  
  METHODS
  The study involved 50 patients with recalcitrant not infected and/or necrotic chronic ulcers. All patients had 0.7 minimum ABPI value; terminal and/or cancer and/or under immunosuppressive therapy patients were excluded. The dressing consisted in a uniform gel layer applied on the lesion, after cleansing with a 0.05% sodium hypochlorite chloroxidating solution. The dressing was changed every 48 hours (or every 24 hours, in case of hyperexuding wound). The effectiveness was assessed by the evaluation of the WBP score changes and area reduction (via the Visitrak™ Digital System) after an observation period of 4 weeks.
  
  
  RESULTS
  All patients achieved area improvement; WBP score improved in more than 90% of the B score patients; pain reduction was reported by all patients: more than 55% of the total number of patients limited the use of analgesic drugs and in 6 cases (12%) they discontinued the antalgic therapy.
  
  
  CONCLUSIONS
  The dressing showed an actual effectiveness, promoting granulation and accelerating epithelialization; no patient suffered from allergy/intolerance and all of them reported a decrease in pain, until complete relief.
authors: Vulnera - Italian Vulnological Center, Turin, Italy - cassino@vulnera.it.
authors: R
authors: R
authors: Cassino
authors: A M
authors: AM
authors: Ippolito
authors: P
authors: P
authors: Cuffaro
authors: A
authors: A
authors: Corsi
authors: O
authors: O
authors: Forma
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003879:Dermatologic Agents / Q000008:administration & dosage*; D005260:Female; D005782:Gels; D006801:Humans; D008297:Male; D009779:Occlusive Dressings; D009821:Oils / Q000008:administration & dosage*; D016877:Oxidants / Q000008:administration & dosage*; D012883:Skin Ulcer / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D003879:Dermatologic Agents; D005782:Gels; D009821:Oils; D016877:Oxidants