title: Dietary agents for prevention and treatment of lung cancer.
abstract: Lung cancer is a prominent cause of cancer-associated mortality worldwide. The main reason for high mortality due to lung cancer is attributable to the fact that the diagnosis is generally made when it has spread beyond a curable stage and cannot be treated surgically or with radiation therapy. Therefore, new approaches like dietary modifications could be extremely useful in reducing lung cancer incidences. Several fruits and vegetables offer a variety of bioactive compounds to afford protection against several diseases, including lung cancer. A number of research studies involving dietary agents provide strong evidence for their role in the prevention and treatment of lung cancer, and have identified their molecular mechanisms of action and potential targets. In this review article, we summarize data from in-vitro and in-vivo studies and where available, in clinical trials, on the effects of some of the most promising dietary agents against lung cancer.
authors: Department of Dermatology, University of Wisconsin, Madison, WI 53706, USA.
authors: Naghma
authors: N
authors: Khan
authors: Department of Dermatology, University of Wisconsin, Madison, WI 53706, USA. Electronic address: hmukhtar@wisc.edu.
authors: Hasan
authors: H
authors: Mukhtar
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000517:prevention & control*; D000284:Administration, Oral; D000818:Animals; D016588:Anticarcinogenic Agents / Q000008:administration & dosage*; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D002392:Catechin / Q000008:administration & dosage / Q000031:analogs & derivatives; D003474:Curcumin / Q000008:administration & dosage; D005419:Flavonoids / Q000008:administration & dosage; D044948:Flavonols; D006801:Humans; D007211:Indoles / Q000008:administration & dosage; D017879:Isothiocyanates / Q000008:administration & dosage; D008175:Lung Neoplasms / Q000188:drug therapy / Q000517:prevention & control*; D010936:Plant Extracts / Q000008:administration & dosage; D059808:Polyphenols / Q000008:administration & dosage
chemical_list: D016588:Anticarcinogenic Agents; D000972:Antineoplastic Agents, Phytogenic; D005419:Flavonoids; D044948:Flavonols; D007211:Indoles; D017879:Isothiocyanates; D010936:Plant Extracts; D059808:Polyphenols; D002392:Catechin; C045651:epigallocatechin gallate; C016517:indole-3-carbinol; D003474:Curcumin; C017875:fisetin
keywords: Dietary agents; Lung cancer; Prevention; Treatment
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