title: Herpes simplex virus type 1 infection in two pet marmosets in Japan.
abstract: An 8-month-old common marmoset (Callithrix jacchus) was presented with tic-like symptoms, and a 2-year-old pigmy marmoset (Callithrix pygmaea) was presented with dyspnea and hypersalivation. Both monkeys died within a few days, and necropsies were performed. Histopathological examinations revealed ulcerative stomatitis with epithelial cell swelling and eosinophilic intranuclear inclusion bodies in the oral epithelium of both cases. In the central and peripheral nervous systems, neuronal cell degeneration with intranuclear inclusion bodies was observed. Immunohistochemical examination using anti-herpes simplex virus type 1 antibody revealed virus antigens in both cases. Both animals had been kept as pets with limited exposure to the ambient environment except via their owners. Therefore, herpes simplex virus type-1 was probably acquired from close contact with their owners.
authors: Miwa Exotic Animal Hospital, 1-25-5, Komagome, Toshima-ku, Tokyo 170-0003, Japan.
authors: Kei
authors: K
authors: Imura
authors: James Kenn
authors: JK
authors: Chambers
authors: Kazuyuki
authors: K
authors: Uchida
authors: Shunsuke
authors: S
authors: Nomura
authors: Satoshi
authors: S
authors: Suzuki
authors: Hiroyuki
authors: H
authors: Nakayama
authors: Yasutsugu
authors: Y
authors: Miwa
mesh_terms: D000818:Animals; D002144:Callithrix; D017809:Fatal Outcome; D005260:Female; D006566:Herpesviridae Infections / Q000662:veterinary*; D018259:Herpesvirus 1, Human / Q000302:isolation & purification*; D007150:Immunohistochemistry / Q000662:veterinary; D007564:Japan; D008297:Male; D008992:Monkey Diseases / Q000821:virology*; D057805:Pets / Q000821:virology*; D015047:Zoonoses / Q000821:virology*
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