title: Wrist flexion and extension torques measured by highly sensitive dynamometer in healthy subjects from 5 to 80 years.
abstract: BACKGROUND
  Wrist movements become impaired with disease progression in various neuromuscular disorders. With the development of new therapies, thorough measurement of muscle strength is crucial to document natural disease progression and to assess treatment efficacy. We developed a new dynamometer enabling wrist flexion and extension torque measurement with high sensitivity. The aims of the present study were to collect norms for healthy children and adults, to compute predictive equations, to assess the reliability of the measurements and to test the feasibility of using the device in patients with a neuromuscular disease.
  
  
  METHODS
  The peak isometric torque of wrist flexion and extension was measured with the MyoWrist dynamometer in 345 healthy subjects aged between 5 and 80 years old and in 9 patients with limb girdle muscle dystrophy type 2 C (LGMD2C) aged between 16 and 38 years old.
  
  
  RESULTS
  Predictive equations are proposed for the wrist flexion and extension strength in children and adults. Intra-rater and inter-rater reliability was good with ICCs higher than 0.9 for both wrist flexion and extension. However, retest values were significantly higher by 4% than test results. The dynamometer was applied with no difficulty to patients with LGMD2C and was sensitive enough to detect strength as weak as 0.82 N.m. From our models, we quantified the mean strength of wrist extension in LGMD2C patients to 39 ± 17% of their predicted values.
  
  
  CONCLUSIONS
  The MyoWrist dynamometer provides reliable and sensitive measurement of both wrist flexion and extension torques. However, a training session is recommended before starting a study as a small but significant learning effect was observed. Strength deficit can be quantified from predictive equations that were computed from norms of healthy children and adults.
authors: Valérie
authors: V
authors: Decostre
authors: Aurélie
authors: A
authors: Canal
authors: Gwenn
authors: G
authors: Ollivier
authors: Isabelle
authors: I
authors: Ledoux
authors: Amélie
authors: A
authors: Moraux
authors: Valérie
authors: V
authors: Doppler
authors: Christine Anne Mary
authors: CA
authors: Payan
authors: Jean-Yves
authors: JY
authors: Hogrel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007537:Isometric Contraction / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009068:Movement; D053580:Muscle Strength / Q000502:physiology*; D053581:Muscle Strength Dynamometer; D011237:Predictive Value of Tests; D012016:Reference Values; D015203:Reproducibility of Results; D019415:Torque; D014953:Wrist / Q000502:physiology*; D055815:Young Adult
references: Muscle Nerve. 2013 Feb;47(2):163-9
references: 23169433
references: Muscle Nerve. 2013 Dec;48(6):897-901
references: 23512655
references: Am J Phys Med Rehabil. 1991 Aug;70(4):201-5
references: 1878179
references: Handb Clin Neurol. 2011;101:41-6
references: 21496623
references: Neuromuscul Disord. 2014 Jul;24(7):604-10
references: 24857365
references: Dev Med Child Neurol. 2012 Oct;54(10):879-85
references: 22713125
references: Dev Med Child Neurol. 2006 Sep;48(9):728-33
references: 16904018
references: J Hand Surg Eur Vol. 2010 Jul;35(6):486-93
references: 20237189
references: Clin Rehabil. 2003 Nov;17(7):693-702
references: 14606734
references: Muscle Nerve. 2013 Sep;48(3):343-56
references: 23681930
references: BMC Musculoskelet Disord. 2012 Sep 18;13:176
references: 22989265
references: BMC Musculoskelet Disord. 2013 Mar 22;14:104
references: 23522186
references: Brain. 2012 Feb;135(Pt 2):483-92
references: 22240777
references: Cell Mol Life Sci. 2013 Dec;70(23):4585-602
references: 23775131
references: Kurume Med J. 2011;57(4):125-32
references: 21778674
references: Mov Disord. 2006 Jan;21(1):18-27
references: 16127719
references: Neuromuscul Disord. 2013 Feb;23(2):139-48
references: 23219352
references: Muscle Nerve. 2013 Sep;48(3):357-68
references: 23674289
references: J Electromyogr Kinesiol. 2007 Aug;17(4):428-36
references: 16806974
references: J Vis Exp. 2011 Apr 12;(50):
references: 21505416
references: J Orthop Sports Phys Ther. 1983;4(4):217-28
references: 18806442
references: Phys Ther. 1996 Mar;76(3):248-59
references: 8602410
references: Arthritis Care Res (Hoboken). 2010 Apr;62(4):465-72
references: 20391500
references: Arch Phys Med Rehabil. 2014 Dec;95(12):2444-69
references: 24909587
references: J Rehabil Med. 2008 Aug;40(8):665-71
references: 19020701
references: Clin Neurophysiol. 2013 Jan;124(1):136-47
references: 22959414
references: Qual Life Res. 2001;10(7):571-8
references: 11822790
references: Int J Sports Med. 2011 Oct;32(10):754-60
references: 21913160
references: Neuromuscul Disord. 2012 Nov;22(11):980-6
references: 22738680
references: Hum Gene Ther. 2004 Nov;15(11):1065-76
references: 15610607
references: Eur J Appl Physiol. 2009 Dec;107(6):715-22
references: 19756710