title: Topiramate-induced palinopsia: a case series and review of the literature.
abstract: BACKGROUND
  To report palinopsia as a possible side effect of topiramate.
  
  
  METHODS
  Case series and review of the literature.
  
  
  RESULTS
  Nine patients in our series, and 4 previously reported patients, who developed palinopsia while on topiramate, are reviewed. All patients were women, and comorbidities included migraine, idiopathic intracranial hypertension, and bulimia nervosa. Palinopsia resolved in 8 patients after stopping or decreasing the dose of topiramate. The lowest dose of topiramate causing palinopsia was 25 mg twice a day. More than half of our patients reported exacerbation of visual disturbance in early morning or late evening.
  
  
  CONCLUSIONS
  Topiramate-induced palinopsia may be underdiagnosed because physicians do not inquire about such visual symptoms.
authors: Department of Ophthalmology and Visual Sciences (SHY, RLL), Yale School of Medicine, New Haven, Connecticut; Departments of Neurology, and Ophthalmology and Visual Sciences (PL), Vanderbilt University School of Medicine, Nashville, Tennessee; and Department of Ophthalmology (MS), University of Texas Health Science Center, San Antonio, Texas.
authors: Samuel H
authors: SH
authors: Yun
authors: Patrick J
authors: PJ
authors: Lavin
authors: Martha P
authors: MP
authors: Schatz
authors: Robert L
authors: RL
authors: Lesser
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D005260:Female; D005632:Fructose / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D007088:Illusions / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D012678:Sensation Disorders / Q000139:chemically induced*; D000077236:Topiramate; D014796:Visual Perception / Q000187:drug effects*
chemical_list: D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose