title: Hexamodal imaging with porphyrin-phospholipid-coated upconversion nanoparticles.
abstract: Hexamodal imaging using simple nanoparticles is demonstrated. Porphyrin-phospholipids are used to coat upconversion nanoparticles in order to generate a new biocompatible material. The nanoparticles are characterized in vitro and in vivo for imaging via fluorescence, upconversion, positron emission tomography, computed tomography, Cerenkov luminescence, and photoacoustic tomography.
authors: Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, NY, 14260, USA.
authors: James
authors: J
authors: Rieffel
authors: Feng
authors: F
authors: Chen
authors: Jeesu
authors: J
authors: Kim
authors: Guanying
authors: G
authors: Chen
authors: Wei
authors: W
authors: Shao
authors: Shuai
authors: S
authors: Shao
authors: Upendra
authors: U
authors: Chitgupi
authors: Reinier
authors: R
authors: Hernandez
authors: Stephen A
authors: SA
authors: Graves
authors: Robert J
authors: RJ
authors: Nickles
authors: Paras N
authors: PN
authors: Prasad
authors: Chulhong
authors: C
authors: Kim
authors: Weibo
authors: W
authors: Cai
authors: Jonathan F
authors: JF
authors: Lovell
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry; D003287:Contrast Media / Q000138:chemical synthesis / Q000737:chemistry; D005240:Feasibility Studies; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000378:metabolism; D008422:Materials Testing; D008807:Mice, Inbred BALB C; D064847:Multimodal Imaging / Q000295:instrumentation; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging / Q000378:metabolism; D053758:Nanoparticles / Q000737:chemistry; D061848:Optical Imaging / Q000295:instrumentation; D019047:Phantoms, Imaging; D010743:Phospholipids / Q000737:chemistry; D061088:Photoacoustic Techniques / Q000295:instrumentation; D011166:Porphyrins / Q000737:chemistry; D049268:Positron-Emission Tomography / Q000295:instrumentation; D014057:Tomography, X-Ray Computed / Q000295:instrumentation; D014422:Turkeys; D014867:Water; D051598:Whole Body Imaging / Q000295:instrumentation
chemical_list: D001672:Biocompatible Materials; D003287:Contrast Media; D010743:Phospholipids; D011166:Porphyrins; D014867:Water
keywords: imaging; multimodal; nanoparticles; porphyrins; upconversion nanoparticles
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