title: Association of neutrophil/lymphocyte ratio and retinal vein occlusion.
abstract: OBJECTIVE
  To evaluate the association between neutrophil/lymphocyte ratio (NLR) and the development of retinal vein occlusion (RVO).
  
  
  METHODS
  Forty patients were included in the study. Forty age- and sex-matched healthy volunteers were recruited as the control group. The RVO diagnosis was made clinically, based on the findings of fundus examination. The NLR and file records of the patients and the control group were compared.
  
  
  RESULTS
  The mean age of patients was 64 ± 12 years. Neutrophil levels were higher in RVO patients compared to the control subjects (5.1 ± 1.9 vs 3.6 ± 1.0, p&lt;0.001). Lymphocyte levels were lower in RVO patients compared with the control subjects (2.0 ± 0.7 vs 2.6 ± 0.9, p = 0.005). The NLR was significantly higher in RVO patients compared with the control subjects (3.0 ± 2.7 vs 1.5 ± 0.3, p&lt;0.001). According to the receiver operator characteristics curve analysis, the optimal cutoff value of NLR to predict RVO was &gt;1.89, with 72.5% sensitivity and 100% specificity.
  
  
  CONCLUSIONS
  The current study demonstrated that higher NLR was associated with the development of RVO. The NLR may be used as a predictive tool for identifying risk for RVO.
authors: 1 Department of Ophthalmology, Cumhuriyet University School of Medicine, Sivas - Turkey.
authors: Ayhan
authors: A
authors: Dursun
authors: Sultan
authors: S
authors: Ozturk
authors: Hasan
authors: H
authors: Yucel
authors: Ayse Vural
authors: AV
authors: Ozec
authors: Feyza Gulac
authors: FG
authors: Dursun
authors: Mustafa Ilker
authors: MI
authors: Toker
authors: Haydar
authors: H
authors: Erdogan
authors: Mustafa Kemal
authors: MK
authors: Arici
authors: Aysen
authors: A
authors: Topalkara
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology*; D012372:ROC Curve; D012170:Retinal Vein Occlusion / Q000097:blood* / Q000175:diagnosis