title: RIFM fragrance ingredient safety assessment, 2,6-Dimethyl-5-heptenal, CAS Registry Number 106-72-9.
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: A M
authors: AM
authors: Api
authors: Member RIFM Expert Panel, Department of Dermatology, Columbia University Medical Center, 161 Fort Washington Ave., New York, NY 10032, United States.
authors: D
authors: D
authors: Belsito
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: S
authors: S
authors: Bhatia
authors: Member RIFM Expert Panel, Department of Occupational & Environmental Dermatology, Malmo University Hospital, Sodra Forstadsgatan 101, Entrance 47, Malmo SE-20502, Sweden.
authors: M
authors: M
authors: Bruze
authors: Member RIFM Expert Panel, 230 Whittier Research Center, University of Nebraska Lincoln, Lincoln, NE 68583-0857, United States.
authors: P
authors: P
authors: Calow
authors: Member RIFM Expert Panel, School of Veterinary Medicine and Animal Science, Department of Pathology, University of Sao Paulo, Av. Prof. dr. Orlando Marques de Paiva, 87, Sao Paulo CEP 05508-900, Brazil.
authors: M L
authors: ML
authors: Dagli
authors: Member RIFM Expert Panel, Department of Toxicology, University of Wuerzburg, Versbacher Str. 9, Würzburg 97078, Germany.
authors: W
authors: W
authors: Dekant
authors: Member RIFM Expert Panel, Oregon Health Science University, 3181 SW Sam Jackson Park Rd., Portland, OR 97239, United States.
authors: A D
authors: AD
authors: Fryer
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States. Electronic address: lkromidas@rifm.org.
authors: L
authors: L
authors: Kromidas
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: S
authors: S
authors: La Cava
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: J F
authors: JF
authors: Lalko
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: A
authors: A
authors: Lapczynski
authors: Member RIFM Expert Panel, Department of Biochemistry, Center in Molecular Toxicology, Vanderbilt University School of Medicine, 638 Robinson Research Building, 2200 Pierce Avenue, Nashville, TN 37232-0146, United States.
authors: D C
authors: DC
authors: Liebler
authors: Member RIFM Expert Panel, Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
authors: Y
authors: Y
authors: Miyachi
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: V T
authors: VT
authors: Politano
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: G
authors: G
authors: Ritacco
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: D
authors: D
authors: Salvito
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: J
authors: J
authors: Shen
authors: Member RIFM Expert Panel, College of Veterinary Medicine, Department of Comparative Medicine, The University of Tennessee, 2407 River Dr., Knoxville, TN 37996-4500, United States.
authors: T W
authors: TW
authors: Schultz
authors: Member RIFM Expert Panel, Department of Pharmacology, College of Medicine, University of Arizona, 1501 North Campbell Avenue, P.O. Box 245050, Tucson, AZ 85724-5050, United States.
authors: I G
authors: IG
authors: Sipes
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: B
authors: B
authors: Wall
authors: Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
authors: D K
authors: DK
authors: Wilcox
mesh_terms: D000447:Aldehydes / Q000737:chemistry / Q000633:toxicity*; D000818:Animals; D003257:Consumer Product Safety; D004249:DNA Damage / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D023381:Endpoint Determination; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D019055:No-Observed-Adverse-Effect Level; D010476:Perfume / Q000737:chemistry / Q000633:toxicity*; D051381:Rats; D018570:Risk Assessment; D018675:Toxicity Tests
chemical_list: D000447:Aldehydes; D010476:Perfume; C000606932:2,6-dimethyl-5-heptenal
keywords: Environmental safety assessment; Genotoxicity; Local respiratory toxicity; Phototoxicity/photoallergenicity; Repeated dose toxicity/developmental and reproductive toxicity; Skin Sensitization