title: Disparities in medication therapy in patients with heart failure across the State of Hawai'i.
abstract: The purpose of this study is to evaluate if heart failure patients in Hawai'i are receiving recommended standard therapy of a select beta-blocker in combination with an ACE inhibitor (ACEI) or angiotensin receptor blocker (ARB), and to determine if a gap in quality of care exists between the different regions within the state. A retrospective claims-based analysis of all adult patients (age > 18 years of age) with CHF who were enrolled in a large health plan in Hawai'i was performed (n = 24,149). Data collected included the presence of pharmaceutical claims for ACEI, ARBs and select β-blockers, region of residence, gender, and age. Multivariable logistic regression was used to examine whether there were regional differences in Hawai'i related to medication usage, after adjustment for age and gender. Results showed that only 28.4 % of patients were placed on the recommended therapy of an ACEI or ARB and a select β-blocker with significant differences being found between different regions. Further research is needed to better understand factors affecting regional differences in prescribing patterns.
authors: Department of Pharmacy Practice, The Daniel K. Inouye College of Pharmacy, University of Hawai'i at Hilo, Hilo, HI.
authors: Roy Alan
authors: RA
authors: Goo
authors: Department of Pharmacy Practice, The Daniel K. Inouye College of Pharmacy, University of Hawai'i at Hilo, Hilo, HI.
authors: Carolyn
authors: C
authors: Ma
authors: Department of Pharmacy Practice, The Daniel K. Inouye College of Pharmacy, University of Hawai'i at Hilo, Hilo, HI.
authors: Deborah Taira
authors: DT
authors: Juarez
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000368:Aged; D000369:Aged, 80 and over; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D005260:Female; D006254:Hawaii; D054625:Healthcare Disparities; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D016015:Logistic Models; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors
keywords: ACEi; ARBs; Congestive Heart Failure (CHF); Hawaii; Hawai‘i
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