title: Interhemispheric interactions of the human thalamic reticular nucleus.
abstract: The thalamic reticular nucleus is an important structure governing the recurrent interactions between the thalamus and cortex that may provide a substrate for unified perception. Despite the importance of the TRN, its activity has been scarcely investigated in vivo in animal models, and never in humans. Here we anatomically identify the human TRN using multiple registered and averaged proton density-weighted structural MRI scans and drive its functional activity with a dual phase-encoded stimulus. We characterize the retinotopic and temporal response properties in the visual sector of the TRN and measured an inhibitory relationship with the contralateral LGN. These observations provide a basis for further gross characterizations of the role of the TRN in human behavior.
authors: Department of Biology and Centre for Vision Research, York University, Toronto, Ontario M3J 1P3, Canada.
authors: Joseph D
authors: JD
authors: Viviano
authors: Department of Biology and Centre for Vision Research, York University, Toronto, Ontario M3J 1P3, Canada keiths@yorku.ca.
authors: Keith A
authors: http://orcid.org/0000-0001-7120-3380
authors: KA
authors: Schneider
mesh_terms: D000328:Adult; D001931:Brain Mapping; D005260:Female; D007839:Functional Laterality; D005829:Geniculate Bodies / Q000502:physiology; D006801:Humans; D020646:Intralaminar Thalamic Nuclei / Q000502:physiology*; D008297:Male; D014796:Visual Perception
keywords: lateral geniculate nucleus; oscillations; retinotopy; temporal response; thalamic reticular nucleus; thalamus
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