title: Sexual function and fertility quality of life in women using in vitro fertilization.
abstract: BACKGROUND
  Women undergoing fertility treatment are likely to report negative changes in sexual function. With the rapid increase in the number of women pursuing in vitro fertilization (IVF), there is a need to better understand how IVF impacts a woman's sexual experiences and quality of life.
  
  
  OBJECTIVE
  This study has three purposes: (i) test the psychometric properties of the Sexual Functioning Questionnaire (SFQ) in a sample of U.S. women undergoing IVF; (ii) compare sexual function of women undergoing IVF with a nonclinical sample of U.S. women; and (iii) identify the aspects of sexual function most related to fertility quality of life (FertiQoL).
  
  
  METHODS
  A total of 136 women who had recently undergone or who were currently undergoing IVF completed a web-based, cross-sectional survey about sexual experiences and quality of life.
  
  
  METHODS
  Data were collected on infertility diagnosis, length of infertility, number of IVF cycles, pregnancy, and birth outcomes. Six domains of sexual function as well as the medical impact of IVF were assessed using the SFQ. A validated instrument was used to measure FertiQoL.
  
  
  RESULTS
  Reliability analyses for the SFQ indicate sufficiently strong fit (Cronbach's alpha = 0.79 to 0.89). Compared with a nonclinical sample, women undergoing IVF scored significantly lower in sexual interest, desire, orgasm, satisfaction, sexual activity, and overall sexual function (P < 0.05). A stepwise linear regression indicated that sexual problems predicted FertiQoL scores (Beta = 4.61, P < 0.01). The most common sexual problems included lack of sexual interest or desire (30%), difficulty with orgasm (15%), vaginal dryness (14%), and vaginal tightness (13%).
  
  
  CONCLUSIONS
  Women undergoing IVF may be at particular risk for sexual problems. Sexual function issues may markedly impact overall quality of life during fertility treatment and should be addressed as an important component of comprehensive care.
authors: Office of Population Research, Princeton University, Princeton, NJ, USA.
authors: Nicole K
authors: NK
authors: Smith
authors: Jody
authors: J
authors: Madeira
authors: Heather R
authors: HR
authors: Millard
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007246:Infertility / Q000523:psychology*; D008875:Middle Aged; D009948:Orgasm; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D012725:Sexual Behavior / Q000523:psychology; D020018:Sexual Dysfunctions, Psychological / Q000523:psychology*; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D013997:Time Factors; D014481:United States; D055815:Young Adult
keywords: Fertility Quality of Life; In Vitro Fertilization; Sexual Function; Sexual Problems