title: Geriatric oral lesions: A multicentric study.
abstract: OBJECTIVE
  To carry out an oral biopsy survey in geriatric patients from the participating institutions.
  
  
  METHODS
  The biopsy records of the participating institutions were reviewed for oral lesions from patients aged 65 years and older diagnosed from 2003 to 2012. Demographic data and the site of the lesions were collected. Histopathological diagnoses were categorized into two categories: non-neoplastic lesions (reactive/inflammatory lesion, cyst, allergic/immunologic disorders, potentially malignant disorders, infection and others) and neoplastic lesions (benign and malignant tumors). Data were analyzed by appropriate statistics using stata11.
  
  
  RESULTS
  Of the 76,045 accessioned cases, 11,346 cases (14.92%) were in geriatric patients. The mean age of the patients was 72.98 ± 6.25 years. A total of 5010 cases (44.16%) were diagnosed in males, whereas 6336 cases (55.84%) were diagnosed in females. The male-to-female ratio was 0.79:1. Non-neoplastic lesions outnumbered the neoplastic counterpart. The five most prevalent oral lesions in the geriatric population in the present study in descending order of frequency were squamous cell carcinoma, focal fibrous hyperplasia (irritation fibroma), radicular cyst, osteomyelitis and epithelial dysplasia, respectively. The site of predilection was labial/buccal mucosa, followed by gingiva, mandibular bone, tongue and maxillary bone, respectively.
  
  
  CONCLUSIONS
  The geriatric oral lesions from the present study showed a similar trend with studies based on histopathological data, but different from the studies based on clinical data. This study also shed more light on potentially malignant disorders, as well as benign and malignant tumors.
authors: Department of Oral Pathology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
authors: Kittipong
authors: K
authors: Dhanuthai
authors: Department of Oral Pathology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
authors: Somsri
authors: S
authors: Rojanawatsirivej
authors: Department of Community Dentistry, Chulalongkorn University, Bangkok, Thailand.
authors: Tewarit
authors: T
authors: Somkotra
authors: Department of Oral Pathology, Kyungpook National University, Kyungpook, South Korea.
authors: Hong-In
authors: HI
authors: Shin
authors: Department of Oral Pathology, Seoul National University, Seoul, South Korea.
authors: Sam-Pyo
authors: SP
authors: Hong
authors: Department of Pathology, Western University, London, Ontario, Canada.
authors: Mark
authors: M
authors: Darling
authors: Department of Pathology, Western University, London, Ontario, Canada.
authors: Nicholas
authors: N
authors: Ledderhof
authors: Department of Oral and Maxillofacial Pathology, Tehran University of Medical Science, Tehran, Islamic Republic of Iran.
authors: Maryam
authors: M
authors: Khalili
authors: Department of Oral Biology and Diagnostic Sciences, Chiangmai University, Chiangmai, Thailand.
authors: Watcharaporn
authors: W
authors: Thosaporn
authors: Department of Oral Diagnosis, Khon Kaen University, Khon Kaen, Thailand.
authors: Pornpop
authors: P
authors: Rattana-Arpha
authors: Department of Tissue Regeneration and Reconstruction, Niigata University, Niigata, Japan.
authors: Takashi
authors: T
authors: Saku
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D009059:Mouth Diseases / Q000473:pathology*
keywords: epidemiology; geriatric patients; histopathologic diagnosis; oral lesions; retrospective study