title: The role of microglia and myeloid immune cells in acute cerebral ischemia.
abstract: The immune response to acute cerebral ischemia is a major contributor to stroke pathobiology. The inflammatory response is characterized by the participation of brain resident cells and peripheral leukocytes. Microglia in the brain and monocytes/neutrophils in the periphery have a prominent role in initiating, sustaining and resolving post-ischemic inflammation. In this review we aim to summarize recent literature concerning the origins, fate and role of microglia, monocytes and neutrophils in models of cerebral ischemia and to discuss their relevance for human stroke.
authors: Feil Family Brain and Mind Research Institute, Weill Cornell Medical College New York, NY, USA.
authors: Corinne
authors: C
authors: Benakis
authors: Feil Family Brain and Mind Research Institute, Weill Cornell Medical College New York, NY, USA.
authors: Lidia
authors: L
authors: Garcia-Bonilla
authors: Feil Family Brain and Mind Research Institute, Weill Cornell Medical College New York, NY, USA.
authors: Costantino
authors: C
authors: Iadecola
authors: Feil Family Brain and Mind Research Institute, Weill Cornell Medical College New York, NY, USA.
authors: Josef
authors: J
authors: Anrather
keywords: cerebral ischemia; microglia; monocytes; myeloid cells; neutrophils; tissue macrophages
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