title: Intrapancreatic ectopic splenic tissue found in a cloned miniature pig.
abstract: Somatic cell nuclear transfer (SCNT) is a cost-effective technique for producing transgenic pigs. However, abnormalities in the cloned pigs might prevent use these animals for clinical applications or disease modeling. In the present study, we generated several cloned pigs. One of the pigs was found to have intrapancreatic ectopic splenic tissue during histopathology analysis although this animal was grossly normal and genetically identical to the other cloned pigs. Ectopic splenic tissue in the pancreas is very rare, especially in animals. To the best of our knowledge, this is the first such report for cloned pigs.
authors: Laboratory Animal Research Center, Samsung Biomedical Research Institute, Suwon 440-746, Korea.
authors: Ok Jae
authors: OJ
authors: Koo
authors: Seung-Kwon
authors: SK
authors: Ha
authors: Sol Ji
authors: SJ
authors: Park
authors: Hee Jung
authors: HJ
authors: Park
authors: Su Jin
authors: SJ
authors: Kim
authors: Daekee
authors: D
authors: Kwon
authors: Jung Taek
authors: JT
authors: Kang
authors: Joon Ho
authors: JH
authors: Moon
authors: Eun Jung
authors: EJ
authors: Park
authors: Goo
authors: G
authors: Jang
authors: Byeong Chun
authors: BC
authors: Lee
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D002828:Choristoma / Q000473:pathology / Q000662:veterinary*; D019976:Cloning, Organism; D053652:Nuclear Transfer Techniques / Q000662:veterinary*; D010179:Pancreas; D013158:Splenic Diseases / Q000473:pathology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000473:pathology*; D013556:Swine, Miniature
keywords: cloned pig; intrapancreatic ectopic splenic tissue; somatic cell nuclear transfer
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