title: Laboratory features and the successful transplantation of allogeneic peripheral blood stem cells in patients with lymphoma-associated hemophagocytic lymphohistiocytosis.
abstract: BACKGROUND
  Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease that is commonly caused by lymphoma. The authors describe laboratory features and the successful treatment of two patients with lymphoma- associated HLH.
  
  
  METHODS
  Hematologic investigations, bone marrow aspirates and biopsies, and PET/CT scans were performed. Both patients received a transplantation of allogenic peripheral blood stem cells after chemotherapy.
  
  
  RESULTS
  The patients achieved complete remission and have survived for three or more years after treatment with chemotherapy and an allogenic peripheral blood stem cell transplantation.
  
  
  CONCLUSIONS
  Allogeneic peripheral blood stem cell transplantation may be the most effective therapy for patients with lymphoma-associated hemophagocytic lymphohistiocytosis.
authors: Li
authors: L
authors: Xudong
authors: He
authors: H
authors: Yi
authors: Wang
authors: W
authors: Dongning
authors: Hu
authors: H
authors: Yuan
authors: Wang
authors: W
authors: Wenwen
authors: Huang
authors: H
authors: Renwei
mesh_terms: D000328:Adult; D001706:Biopsy; D001856:Bone Marrow Examination; D017024:Chemotherapy, Adjuvant; D005260:Female; D006403:Hematologic Tests; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D008223:Lymphoma / Q000150:complications* / Q000175:diagnosis; D008297:Male; D020360:Neoadjuvant Therapy; D036102:Peripheral Blood Stem Cell Transplantation; D049268:Positron-Emission Tomography; D012074:Remission Induction; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D055815:Young Adult