title: Characteristics of neoplastic cardiac tamponade and prognosis after pericardiocentesis: a single-center study of 113 consecutive cancer patients.
abstract: BACKGROUND
  Neoplastic cardiac tamponade (NCT) is a life-threatening complication of cancer. The interval between cancer diagnosis and NCT onset and the prognosis after pericardiocentesis may differ according to cancer type.
  
  
  RESULTS
  We performed a retrospective study of 113 patients (54 % male) with NCT who underwent pericardiocentesis at Niigata Cancer Center Hospital between 1992 and 2013. Mean age at NCT was 61.2 years (range 15.9-94.8 years). The most common underlying cancers were lung cancer (59.2 %), breast cancer (21.2 %), lymphoma/leukemia (5.3 %), and gastric/esophageal cancer (5.3 %). The median time from cancer diagnosis to NCT onset was 9.0, 60.4, 5.6, and 8.0 months for lung cancer, breast cancer, lymphoma/leukemia, and gastric/esophageal cancer, respectively. Kaplan-Meier survival estimates were worse for breast cancer patients with NCT than for matched breast cancer patients without NCT (P < 0.0001). Median survival time after pericardiocentesis was 2.9, 4.2, 2.3, and 0.6 months for lung cancer, breast cancer, lymphoma/leukemia, and gastric/esophageal cancer, respectively; one-year survival after pericardiocentesis was 6.0, 16.7, 33.3, and 0 %, respectively.
  
  
  CONCLUSIONS
  The interval between cancer diagnosis and NCT onset, the impact of NCT on prognosis, and the prognosis after pericardiocentesis differed according to cancer type. Healthcare practitioners caring for patients with NCT should recognize the differences between cancer types and customize their care accordingly.
authors: Department of Cardiology, Niigata Cancer Center Hospital, Chu-o-ku Kawagishicho 2-15-3, Niigata, 951-8560, Japan.
authors: Tsugumi
authors: T
authors: Takayama
authors: Department of Cardiology, Niigata Cancer Center Hospital, Chu-o-ku Kawagishicho 2-15-3, Niigata, 951-8560, Japan. okuray@niigata-cc.jp.
authors: Yuji
authors: Y
authors: Okura
authors: Department of Internal Medicine, Kamo Hospital, Niigata, Japan.
authors: Yoshinobu
authors: Y
authors: Okada
authors: Department of Pathology, Niigata Cancer Center Hospital, Niigata, Japan.
authors: Keiichi
authors: K
authors: Honma
authors: Department of Digestive Surgery, Niigata Cancer Center Hospital, Niigata, Japan.
authors: Atsushi
authors: A
authors: Nashimoto
authors: Department of Breast Surgery, Niigata Cancer Center Hospital, Niigata, Japan.
authors: Nobuaki
authors: N
authors: Sato
authors: Department of Respiratory Medicine, Niigata Cancer Center Hospital, Niigata, Japan.
authors: Akira
authors: A
authors: Yokoyama
authors: Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors: Tohru
authors: T
authors: Minamino
mesh_terms: D000328:Adult; D000368:Aged; D002305:Cardiac Tamponade / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D020519:Pericardiocentesis; D011379:Prognosis; D012189:Retrospective Studies
keywords: Neoplastic cardiac tamponade; Pericardiocentesis; Prognosis
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