title: Hemorrhagic retinopathy in an infant with hemolytic-uremic syndrome.
abstract: We describe the case of a 23-month-old female infant with a diagnosis of hemolytic uremic syndrome (HUS) and hemorrhagic retinopathy. The patient had a past history of abdominal pain, bloody diarrhea, and acute renal failure. On ophthalmologic examination, indirect ophthalmoscopy revealed extensive areas of flame-shaped hemorrhage, cotton wool spots, macular edema and optic nerve head neovascularization in both eyes. Fluorescein angiography showed severe bilateral retinal ischemia and neovascularization leakage in disk. The patient, who had the visual acuity of 20/1000 in the right eye (OD) and 20/540 in the left eye (OS) at the first examination, was treated with panretinal photocoagulation (PRP) and presented at the end of the 6th month of follow-up improvement to 20/540 in OD and 20/270 in OS. There was also a regression of disc neovascularization, hemorrhages and macular edema. Despite intense retinal ischemia, there were no complications related to angiogenesis such as vitreous hemorrhage and/or neovascular glaucoma. We describe, in this report, the association between hemorrhagic retinopathy with features of Purtscher-like disease and HUS.
authors: Ophthalmology Department, Centro de Referência em Oftalmologia, Goiânia, GO, Brazil.
authors: João Caetano Ávila
authors: JC
authors: Geraissate
authors: Ophthalmology Department, Universidade Federal de Goiás, Goiânia, GO, Brazil.
authors: Rafael Eidi
authors: RE
authors: Yamamoto
authors: Ophthalmology Department, Centro de Referência em Oftalmologia, Goiânia, GO, Brazil.
authors: David Leonardo Cruvinel
authors: DL
authors: Isaac
authors: Ophthalmology Department, Centro de Referência em Oftalmologia, Goiânia, GO, Brazil.
authors: Marcos Pereira de
authors: MP
authors: Ávila
mesh_terms: D005260:Female; D005451:Fluorescein Angiography; D006463:Hemolytic-Uremic Syndrome / Q000150:complications*; D006801:Humans; D007223:Infant; D017075:Laser Coagulation / Q000379:methods; D009389:Neovascularization, Pathologic / Q000601:surgery; D012166:Retinal Hemorrhage / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology