title: Validation of Autism Spectrum Disorder Diagnoses in Large Healthcare Systems with Electronic Medical Records.
abstract: To identify factors associated with valid Autism Spectrum Disorder (ASD) diagnoses from electronic sources in large healthcare systems. We examined 1,272 charts from ASD diagnosed youth <18 years old. Expert reviewers classified diagnoses as confirmed, probable, possible, ruled out, or not enough information. A total of 845 were classified with 81% as a confirmed, probable, or possible ASD diagnosis. The predictors of valid ASD diagnoses were >2 diagnoses in the medical record (OR 2.94; 95% CI 2.03-4.25; p < 0.001) and being male (OR 1.51; 95% CI 1.05-2.17; p = 0.03). In large integrated healthcare settings, at least two diagnoses can be used to identify ASD patients for population-based research.
authors: Department of Research and Evaluation, Kaiser Permanente Southern California, 100 S. Los Robles, 2nd Floor, Pasadena, CA, 91104, USA, Karen.J.Coleman@kp.org.
authors: Karen J
authors: KJ
authors: Coleman
authors: Marta A
authors: MA
authors: Lutsky
authors: Vincent
authors: V
authors: Yau
authors: Yinge
authors: Y
authors: Qian
authors: Magdalena E
authors: ME
authors: Pomichowski
authors: Phillip M
authors: PM
authors: Crawford
authors: Frances L
authors: FL
authors: Lynch
authors: Jeanne M
authors: JM
authors: Madden
authors: Ashli
authors: A
authors: Owen-Smith
authors: John A
authors: JA
authors: Pearson
authors: Kathryn A
authors: KA
authors: Pearson
authors: Donna
authors: D
authors: Rusinak
authors: Virginia P
authors: VP
authors: Quinn
authors: Lisa A
authors: LA
authors: Croen
mesh_terms: D000293:Adolescent; D000067877:Autism Spectrum Disorder / Q000175:diagnosis*; D003695:Delivery of Health Care / Q000379:methods* / Q000592:standards; D057286:Electronic Health Records; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
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