title: Potential use of glioblastoma tumorsphere: clinical credentialing.
abstract: A decade ago, cancer stem cells (CSCs) were introduced as target cells for an innovative cancer treatment. Particularly, there have been a lot of biological researches on glioblastoma (GBM) CSCs. However, as there is a comprehensive change in the concept of CSCs, it is required to review how the different CSCs for patients can be clinically used, or clinical credentialing, and summarize the possibilities of clinical credentialing. In this regard, this review aims to introduce the tumorsphere obtained from GBM specimen and summarize the clinical dilemma and clinically applicable areas.
authors: Department of Neurosurgery, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Republic of Korea, seokgu9@kornet.net.
authors: Seok-Gu
authors: SG
authors: Kang
authors: Jae-Ho
authors: JH
authors: Cheong
authors: Yong Min
authors: YM
authors: Huh
authors: Eui Hyun
authors: EH
authors: Kim
authors: Sun Ho
authors: SH
authors: Kim
authors: Jong Hee
authors: JH
authors: Chang
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000379:methods*; D005909:Glioblastoma / Q000473:pathology* / Q000628:therapy; D006801:Humans; D058990:Molecular Targeted Therapy; D014411:Neoplastic Stem Cells / Q000378:metabolism*