title: Evaluation of choroidal thickness using spectral-domain optical coherence tomography in patients with migraine: a comparative study.
abstract: OBJECTIVE
  To assess choroidal thickness in patients with migraine and compare them with healthy controls, using spectral-domain optical coherence tomography (OCT).
  
  
  METHODS
  In this prospective case-control study, choroidal thicknesses of 20 newly diagnosed migraine patients and 20 age- and sex-matched healthy subjects were measured using a high-speed, high-resolution frequency domain (FD) OCT device (λ = 840 nm, 26.000 A-scans/s, 5 µm axial resolution). All patients underwent a complete ophthalmic examination before the measurements. OCT measurements were taken at the same time of day (9:00 AM), in order to minimize the effects of diurnal variation.
  
  
  RESULTS
  There was a statistically significant difference in median choroidal thickness between the migraine patients (277.00 [interquartile range (IQR) 85.75] µm) and controls (301.00 [IQR 90.50] µm) (p = 0.012). There were significant differences at all measurement points (p<0.05 for all).
  
  
  CONCLUSIONS
  The decreased choroidal thickness of patients with migraine might be related to the vascular pathology of the disease. Further studies are needed to evaluate the etiopathologic relationship between choroidal thickness and migraine.
authors: 1 Baskent University School of Medicine, Department of Ophthalmology, Konya - Turkey.
authors: Aylin
authors: A
authors: Karalezli
authors: Guner
authors: G
authors: Celik
authors: Bengu Ekinci
authors: BE
authors: Koktekir
authors: Cem
authors: C
authors: Kucukerdonmez
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002829:Choroid / Q000473:pathology*; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000150:complications*; D009929:Organ Size; D010808:Physical Examination; D011446:Prospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*