title: A novel functional electrical stimulation-control system for restoring motor function of post-stroke hemiplegic patients.
abstract: Hemiparesis is one of the most common consequences of stroke. Advanced rehabilitation techniques are essential for restoring motor function in hemiplegic patients. Functional electrical stimulation applied to the affected limb based on myoelectric signal from the unaffected limb is a promising therapy for hemiplegia. In this study, we developed a prototype system for evaluating this novel functional electrical stimulation-control strategy. Based on surface electromyography and a vector machine model, a self-administered, multi-movement, force-modulation functional electrical stimulation-prototype system for hemiplegia was implemented. This paper discusses the hardware design, the algorithm of the system, and key points of the self-oscillation-prone system. The experimental results demonstrate the feasibility of the prototype system for further clinical trials, which is being conducted to evaluate the efficacy of the proposed rehabilitation technique.
authors: Institute of RF- & OE-ICs, Southeast University, Nanjing, Jiangsu Province, China.
authors: Zonghao
authors: Z
authors: Huang
authors: Institute of RF- & OE-ICs, Southeast University, Nanjing, Jiangsu Province, China ; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu Province, China.
authors: Zhigong
authors: Z
authors: Wang
authors: State Key Lab of Bioelectronics, Southeast University, Nanjing, Jiangsu Province, China ; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu Province, China.
authors: Xiaoying
authors: X
authors: Lv
authors: State Key Lab of Bioelectronics, Southeast University, Nanjing, Jiangsu Province, China.
authors: Yuxuan
authors: Y
authors: Zhou
authors: Institute of RF- & OE-ICs, Southeast University, Nanjing, Jiangsu Province, China.
authors: Haipeng
authors: H
authors: Wang
authors: Institute of RF- & OE-ICs, Southeast University, Nanjing, Jiangsu Province, China.
authors: Sihao
authors: S
authors: Zong
keywords: functional electrical stimulation; motor function; nerve regeneration; neural regeneration; rehabilitation; stimulator circuit; stroke; surface electromyography
references: Neurorehabil Neural Repair. 2008 Mar-Apr;22(2):111-21
references: 17876068
references: Lancet Neurol. 2004 Jul;3(7):391-3
references: 15207791
references: Stroke. 2004 Nov;35(11 Suppl 1):2699-701
references: 15375308
references: Arch Phys Med Rehabil. 2007 Apr;88(4):513-20
references: 17398254
references: Phys Ther. 2007 Jul;87(7):942-53
references: 17472948
references: J Rehabil Res Dev. 1999 Jul;36(3):237-51
references: 10659807
references: Science. 1996 Jun 21;272(5269):1791-4
references: 8650578
references: J Neurosci Methods. 2005 Feb 15;141(2):171-98
references: 15661300
references: Neurorehabil Neural Repair. 2010 Jan;24(1):42-51
references: 19729583
references: Arch Phys Med Rehabil. 1993 Apr;74(4):347-54
references: 8466415
references: J Electromyogr Kinesiol. 2000 Jun;10(3):189-96
references: 10818340
references: Arch Phys Med Rehabil. 2002 Jul;83(7):952-9
references: 12098155
references: Circulation. 2013 Jan 1;127(1):e6-e245
references: 23239837
references: Conf Proc IEEE Eng Med Biol Soc. 2012;2012:314-7
references: 23365893
references: Stroke. 2000 Jun;31(6):1360-4
references: 10835457
references: J Biomech. 2010 May 28;43(8):1573-9
references: 20206934
references: J Electromyogr Kinesiol. 2001 Jun;11(3):217-29
references: 11335152
references: Pflugers Arch. 2004 Aug;448(5):525-32
references: 15168123
references: Arch Phys Med Rehabil. 2008 May;89(5):856-64
references: 18452732
references: IEEE Trans Biomed Eng. 1983 Jan;30(1):62-6
references: 6826188
references: Lancet Neurol. 2004 Sep;3(9):528-36
references: 15324721
references: Arch Phys Med Rehabil. 2005 Nov;86(11):2157-64
references: 16271564
references: Annu Rev Biomed Eng. 2005;7:327-60
references: 16004574
references: Prog Neurobiol. 2005 Apr;75(5):309-20
references: 15885874
references: Electroencephalogr Clin Neurophysiol. 1972 May;32(5):471-83
references: 4112299
references: JAMA. 2004 Oct 20;292(15):1853-61
references: 15494583
references: Med Biol Eng Comput. 1990 Sep;28(5):389-97
references: 2277538
references: Lancet Neurol. 2007 May;6(5):456-64
references: 17434100