title: Deep neck infections originating from the major salivary glands.
abstract: OBJECTIVE
  Before the widespread use of antibiotics, most deep neck infections (DNIs) stemmed from complicated pharyngeal infections. Nowadays, they seem to be due mainly to dental infections. In 2010, our group reported that DNIs originated from a major salivary gland in 14% of cases. The main endpoint of the present investigation was to review our experience of the diagnosis and treatment of DNIs of salivary gland origin. We also compared the characteristics of DNIs originating from salivary glands with those originating elsewhere.
  
  
  METHODS
  Between 2000 and 2011, 44 patients were treated for DNIs of salivary origin at our institution. These patients were compared with 191 cases of DNI diagnosed as having other sites of origin.
  
  
  CONCLUSIONS
  In the present series, DNIs originating from a major salivary gland accounted for 19% of all cases of DNI of known origin. Patients with DNI of salivary gland origin were more likely to be elderly than those whose DNI originated from elsewhere (p=0.000). Our multivariate statistical model showed that comorbidities (p=0.051, statistical trend) and the need for surgical treatment (p=0.028) independently predicted long-term hospitalization for DNIs originating from a major salivary gland.
authors: Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy.
authors: Niccolo'
authors: N
authors: Favaretto
authors: Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy.
authors: Elena
authors: E
authors: Fasanaro
authors: Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy.
authors: Alberto
authors: A
authors: Staffieri
authors: Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy.
authors: Rosario
authors: R
authors: Marchese-Ragona
authors: Department of Neurosciences, Otolaryngology Section, Treviso Branch, University of Padova, Treviso, Italy.
authors: Claudia
authors: C
authors: Staffieri
authors: Department of Medicine DIMED, University of Padova, Padova, Italy.
authors: Luciano
authors: L
authors: Giacomelli
authors: Department of Medicine DIMED, University of Padova, Padova, Italy.
authors: Roberto
authors: R
authors: Stramare
authors: Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy.
authors: Giancarlo
authors: G
authors: Ottaviano
authors: Department of Neurosciences, Otolaryngology Section, University of Padova, Padova, Italy. Electronic address: gino.marioni@unipd.it.
authors: Gino
authors: G
authors: Marioni
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections; D004322:Drainage / Q000379:methods*; D005260:Female; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009333:Neck; D000039:Peritonsillar Abscess / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D011379:Prognosis; D017703:Retropharyngeal Abscess / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D012189:Retrospective Studies; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents