title: Cancer of the gingiva.
abstract: Cancer of the gingiva is a rare disease in the Western World. It most commonly affects elderly population. Because of its rarity, the reporting on the disease is sparse and often grouped with other subsites of oral cancer, which makes conclusions difficult to interpret. The aim of this paper is to review the literature on gingival cancer as a specific subsite of oral cancer and report on published prognostic factors as well as treatment of local and regional disease. We also present differences between gingival cancer subgroups, mandibular and maxillary gingival cancer. In addition, both surgical and oncological treatments are reviewed. It seems that surgery is the preferred initial treatment approach for the majority of patients with gingival cancer, although adjuvant radiation, with or without chemotherapy, is commonly recommended to increase locoregional control.
authors: Division of Ear, Nose and Throat Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital, S-171 76, Stockholm, Sweden. rusana.bark@karolinska.se.|Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Karolinska University Hospital, 17176, Stockholm, Sweden. rusana.bark@karolinska.se.
authors: Rusana
authors: R
authors: Bark
authors: Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, S-171 76, Stockholm, Sweden.
authors: Claes
authors: C
authors: Mercke
authors: Division of Ear, Nose and Throat Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital, S-171 76, Stockholm, Sweden.
authors: Eva
authors: E
authors: Munck-Wikland
authors: Medical Device Consultancy, 1219, 18th Street, San Francisco, CA, 94107, USA.
authors: Natalie Ann
authors: NA
authors: Wisniewski
authors: Division of Ear, Nose and Throat Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Karolinska University Hospital, S-171 76, Stockholm, Sweden.
authors: Lalle
authors: L
authors: Hammarstedt-Nordenvall
mesh_terms: D003952:Diagnostic Imaging; D005260:Female; D005887:Gingival Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008334:Mandible; D000072662:Margins of Excision; D008437:Maxilla; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant
keywords: Cancer of the alveolar crest; Cancer of the alveolar ridge; Gingival cancer; Head and neck cancer; Mandibular gingival cancer; Maxillary gingival cancer; Oral cancer
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