title: Serum level of vitamin D3 in cutaneous melanoma.
abstract: OBJECTIVE
  To compare the level of vitamin D3 in cutaneous melanoma patients, with or without disease activity, with reference values and with patients from a general hospital.
  
  
  METHODS
  The serum levels of vitamin D3 were measured in cutaneous melanoma patients, aged 20 to 88 years, both genders, from January 2010 to December 2013. The samples from the general group were processed at Hospital Israelita Albert Einstein (control group). Data analysis was performed using the Statistics software.
  
  
  RESULTS
  A total of 100 patients were studied, 54 of them men, with mean age of 54.67 years, and 95 Caucasian. Out of these 100 patients, 17 had active disease. The average levels of vitamin D3 in the melanoma patients were lower than the level considered sufficient, but above the average of the control group. Both groups (with or without active disease) of patients showed a similar distribution of vitamin D3 deficiency.
  
  
  CONCLUSIONS
  Vitamin D3 levels in melanoma patients were higher than those of general patients and lower than the reference level. If the reference values are appropriate, a large part of the population had insufficient levels of vitamin D, including those with melanoma, or else, this standard needs to be reevaluated. No difference in vitamin D3 levels was found among melanoma patients with or without active disease. More comprehensive research is needed to assess the relation between vitamin D and melanoma.
authors: Hospital Israelita Albert Einstein, Brazil.
authors: Renato Santos de
authors: RS
authors: Oliveira Filho
authors: Hospital Israelita Albert Einstein, Brazil.
authors: Daniel Arcuschin de
authors: DA
authors: Oliveira
authors: Hospital Israelita Albert Einstein, Brazil.
authors: Vitor Augusto Melão
authors: VA
authors: Martinho
authors: Hospital A.C. Camargo, Brazil.
authors: Célia Beatriz Gianotti
authors: CB
authors: Antoneli
authors: Universidade Cidade de São Paulo, Brazil.
authors: Ludmilla Altino de Lima
authors: LA
authors: Marcussi
authors: Hospital Israelita Albert Einstein, Brazil.
authors: Carlos Eduardo dos Santos
authors: CE
authors: Ferreira
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002762:Cholecalciferol / Q000097:blood* / Q000172:deficiency; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000097:blood*; D008875:Middle Aged; D012016:Reference Values; D012737:Sex Factors; D012878:Skin Neoplasms / Q000097:blood*; D055815:Young Adult
chemical_list: D002762:Cholecalciferol
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