title: Role and Efficacy of L-PRFmatrix in the Regeneration of Periodontal Defect: A New Perspective.
abstract: The ultimate goal of periodontal therapy is to achieve complete wound healing and regeneration of the periodontal unit. The therapeutic use of L-PRF matrix constitutes a relatively new biotechnology that has been a breakthrough in the acceleration of hard and soft tissue healing. Platelet-rich fibrin (PRF) belongs to a new generation of platelet concentrates, with simplified processing and without biochemical blood handling. The slow polymerization during PRF preparation seems to generate a fibrin network very similar to the natural one. Such a network leads to a more efficient cell migration and proliferation and thus cicatrization. This article proposes an overview of use of platelet-rich fibrin in management of periodontal hard and soft tissue defects and goes on to describe the clinical benefits of PRF and its advantage over PRP.
authors: Reader, Department of Periodontology, Rajarajeshwari Dental College And Hospital , Bangalore, Karnataka, India .
authors: Anuroopa
authors: A
authors: P
authors: Private Practice, Belgaum, Karnataka, India .
authors: Padmavathi
authors: P
authors: Patil
authors: Associate Professor, Department of Periodontology, Rajarajeshwari Dental College And Hospital , Bangalore, Karnataka, India .
authors: Vinaya
authors: V
authors: Kumar R
authors: Professor, Department of Periodontology, Rajarajeshwari Dental College And Hospital , Bangalore, Karnataka, India .
authors: Krishna
authors: K
authors: Kripal
keywords: Blood products; L-PRF matrix; PRP; Periodontal defects; Regeneration
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