title: Oral leukoplakia development in patients with pre-existing oral lichen planus.
abstract: Oral leukoplakia and oral lichen planus are conditions that have the potential to transform into squamous cell carcinoma. This article describes a series of nine patients with an initial clinical-microscopic diagnosis of lichen planus. During close follow-up, these patients developed localized areas of leukoplakia at intervals ranging from one and a half to six and a half years. While both conditions may present with white and red oral mucosal changes, their management differs with leukoplakia requiring surgical intervention, therefore accurate diagnosis is imperative.
authors: Nita
authors: N
authors: Chainani-Wu
authors: Daniel M
authors: DM
authors: Purnell
authors: Sol
authors: S
authors: Silverman
mesh_terms: D001706:Biopsy; D005500:Follow-Up Studies; D006801:Humans; D007972:Leukoplakia, Oral / Q000473:pathology*; D017676:Lichen Planus, Oral / Q000473:pathology*; D009061:Mouth Mucosa / Q000473:pathology; D011230:Precancerous Conditions / Q000473:pathology; D012307:Risk Factors