title: Two new flavonoids from the roots of Scutellaria baicalensis.
abstract: One new flavone, 5,7-dihydroxy-8,2',3',6'-tetramethoxyflavone (1), and one new flavonol, 5,7,6'-trihydroxy-2'-methoxyflavonol (2), were isolated from the roots of Scutellaria baicalensis, and their structures were elucidated on the basis of extensive spectroscopic evidences, especially 1D and 2D NMR and HR-ESI-MS experiments. The structure features of these new compounds lie in the substitution at both C-2' and C-6' positions of B-ring by hydroxyl or methoxyl groups.
authors: a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.
authors: Hai-Lin
authors: HL
authors: Long
authors: Guo-Ying
authors: GY
authors: Xu
authors: An-Jun
authors: AJ
authors: Deng
authors: Zhi-Hong
authors: ZH
authors: Li
authors: Lin
authors: L
authors: Ma
authors: Yao
authors: Y
authors: Lu
authors: Zhi-Hui
authors: ZH
authors: Zhang
authors: Feng
authors: F
authors: Wu
authors: Hai-Lin
authors: HL
authors: Qin
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D047309:Flavones / Q000737:chemistry; D044948:Flavonols / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D031364:Scutellaria baicalensis / Q000737:chemistry*
chemical_list: C000602406:5,7,6'-trihydroxy-2'-methoxyflavonol; C000602405:5,7-dihydroxy-8,2',3',6'-tetramethoxyflavone; D004365:Drugs, Chinese Herbal; D047309:Flavones; D044948:Flavonols
keywords: 5,7,6′-trihydroxy-2′-methoxyflavonol; 5,7-dihydroxy-8,2′,3′,6′-tetramethoxyflavone; Labiatae; Scutellaria baicalensis; flavonoids