title: Association between dietary patterns and serum leptin-to-adiponectin ratio in apparently healthy adults.
abstract: OBJECTIVE
  Dietary patterns reflect diet and nutritional habits of individuals in a society. Various dietary patterns could influence leptin and adiponectin secretion from adipose tissue. These hormones are associated with metabolic diseases. It is suggested that the leptin-to-adiponectin (L/A) ratio might be a more useful diagnostic marker in predicting chronic diseases than leptin and adiponectin separately. The aim of this study was to investigate the association between various dietary patterns and L/A ratio in Iranian adults.
  
  
  METHODS
  This cross-sectional study was conducted on 150 apparently healthy subjects aged 25-50 years in Tabriz, Iran. Dietary patterns were determined using 132-item semiquantitative food frequency questionnaire on a 5-point scale. Weight, height, waist circumference (WC), as well as fasting serum leptin and adiponectin levels were measured to assess the association between dietary patterns and L/A ratio.
  
  
  RESULTS
  Four major dietary patterns were identified using a factor analysis approach: Western, healthy, mixed, and traditional dietary patterns. Linear regression analysis showed that a Western dietary pattern was negatively associated with serum adiponectin concentration, even after adjusting for the confounders (r = -0.19, p = 0.02). No statistically significant associations were found between any dietary pattern and leptin (r = -0.14, p = 0.06) or L/A ratio (r = -0.10, p = 0.09).
  
  
  CONCLUSIONS
  Our findings indicate an inverse association between a Western dietary pattern and serum adiponectin levels but not for serum leptin or L/A ratio.
authors: a Nutrition Research Center, School of Nutrition, Tabriz University of Medical Sciences , Tabriz , IRAN.
authors: Hamed
authors: H
authors: Jafari-Vayghan
authors: Ali
authors: A
authors: Tarighat-Esfanjani
authors: Mohammad Asghari
authors: MA
authors: Jafarabadi
authors: Mehrangiz
authors: M
authors: Ebrahimi-Mameghani
authors: Sevda Saleh
authors: SS
authors: Ghadimi
authors: Zahra
authors: Z
authors: Lalezadeh
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000328:Adult; D001827:Body Height; D001835:Body Weight; D003430:Cross-Sectional Studies; D004032:Diet / Q000706:statistics & numerical data*; D005215:Fasting / Q000097:blood; D005247:Feeding Behavior; D005260:Female; D006304:Health Status; D006801:Humans; D007492:Iran; D020738:Leptin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D055105:Waist Circumference
chemical_list: C499918:ADIPOQ protein, human; D052242:Adiponectin; D020738:Leptin
keywords: adiponectin; adults; dietary pattern; healthy; leptin