title: Breakpoints and drug exposure are inevitably closely linked.
authors: University of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands j.w.c.alffenaar@umcg.nl.
authors: J W C
authors: JW
authors: Alffenaar
authors: University of Groningen, University Medical Center Groningen, Pulmonary Diseases and Tuberculosis, Groningen, The Netherlands Tuberculosis Center Beatrixoord, Haren, The Netherlands.
authors: O W
authors: OW
authors: Akkerman
authors: University of Groningen, University Medical Center Groningen, Department of Clinical Pharmacy and Pharmacology, Groningen, The Netherlands.
authors: M S
authors: MS
authors: Bolhuis
authors: Radboud University Medical Center and University Lung Centre Dekkerswald, Nijmegen, The Netherlands.
authors: M J
authors: MJ
authors: Boeree
authors: University of Groningen, University Medical Center Groningen, Pulmonary Diseases and Tuberculosis, Groningen, The Netherlands Tuberculosis Center Beatrixoord, Haren, The Netherlands.
authors: W C M
authors: WC
authors: de Lange
authors: University of Groningen, University Medical Center Groningen, Department of Internal Medicine, Groningen, The Netherlands.
authors: T S
authors: TS
authors: van der Werf
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D008297:Male; D012293:Rifampin / Q000627:therapeutic use*; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D007538:Isoniazid; D012293:Rifampin
references: Am J Respir Crit Care Med. 2013 May 15;187(10):1127-34
references: 23525933
references: Antimicrob Agents Chemother. 2014 Oct;58(10):6111-5
references: 25092691
references: Antimicrob Agents Chemother. 2003 Jul;47(7):2118-24
references: 12821456
references: Clin Infect Dis. 2011 May;52(9):e194-9
references: 21467012
references: Clin Infect Dis. 2014 Nov 15;59(10):1364-74
references: 25097082
references: Eur Respir J. 2014 Jul;44(1):23-63
references: 24659544
references: Int J Tuberc Lung Dis. 2014 Oct;18(10):1180-7
references: 25216831