title: On utilizing uncertainty information in template-based EEG-fMRI ballistocardiogram artifact removal.
abstract: The correction of ballistocardiogram artifacts in simultaneous EEG-fMRI often yields unsatisfactory results. To improve the signal-to-noise ratio (SNR) of results, we inferred EEG signal uncertainty from postcorrection artifact residuals and computed the uncertainty-weighted mean of ERPs. Using an uncertainty-weighted mean significantly and consistently reduced both inter- and intrasubject SEM in the analysis of auditory evoked responses (AER, indicated by the N1-P2 complex) and in the effects of an auditory oddball paradigm (N1-P3 complex, standard-deviant difference). SNR increased by 3% on average for the AER amplitude (intrasubject) and 17% on average for the auditory oddball ERP (intersubject). This demonstrates that weighting by uncertainty complements existing artifact correction algorithms to increase SNR in ERPs. More specifically, it is an efficient method to utilize seemingly corrupt (difficult-to-correct) EEG data that might otherwise be discarded.
authors: Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany.
authors: Marc-Andre
authors: MA
authors: Schulz
authors: Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany.|Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
authors: Christina
authors: C
authors: Regenbogen
authors: Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Heidelberg, Mannheim, Germany.
authors: Carolin
authors: C
authors: Moessnang
authors: Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany.|JARA Translational Brain Medicine.
authors: Irene
authors: I
authors: Neuner
authors: Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, UK.
authors: Andreas
authors: A
authors: Finkelmeyer
authors: Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany.|JARA Translational Brain Medicine.
authors: Ute
authors: U
authors: Habel
authors: Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany.|JARA Translational Brain Medicine.
authors: Thilo
authors: T
authors: Kellermann
mesh_terms: D000328:Adult; D001450:Ballistocardiography / Q000379:methods*; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D012815:Signal Processing, Computer-Assisted; D059629:Signal-To-Noise Ratio; D035501:Uncertainty; D055815:Young Adult
keywords: Artifact removal; Ballistocardiogram; Electroencephalography; Event-related potential; Functional magnetic resonance imaging; Propagation of uncertainty; Simultaneous EEG-fMRI