title: Frequency and clinical predictors of coronary artery disease in chronic renal failure renal transplant candidates.
abstract: OBJECTIVE
  Cardiovascular diseases are major causes of mortality in chronic renal failure patients before and after renal transplantation. Among them, coronary disease presents a particular risk; however, risk predictors have been used to diagnose coronary heart disease. This study evaluated the frequency and importance of clinical predictors of coronary artery disease in chronic renal failure patients undergoing dialysis who were renal transplant candidates, and assessed a previously developed scoring system.
  
  
  METHODS
  Coronary angiographies conducted between March 2008 and April 2013 from 99 candidates for renal transplantation from two transplant centers in São Paulo state were analyzed for associations between significant coronary artery diseases (≥70% stenosis in one or more epicardial coronary arteries or ≥50% in the left main coronary artery) and clinical parameters.
  
  
  RESULTS
  Univariate logistic regression analysis identified diabetes, angina, and/or previous infarction, clinical peripheral arterial disease and dyslipidemia as predictors of coronary artery disease. Multiple logistic regression analysis identified only diabetes and angina and/or previous infarction as independent predictors.
  
  
  CONCLUSIONS
  The results corroborate previous studies demonstrating the importance of these factors when selecting patients for coronary angiography in clinical pretransplant evaluation.
authors: Medicine Department, Division of Cardiology at Catholic University of São Paulo , Sorocaba , Brazil .
authors: Emerson
authors: E
authors: de Albuquerque Seixas
authors: Beatriz Leone
authors: BL
authors: Carmello
authors: Christiane Akemi
authors: CA
authors: Kojima
authors: Mariana Moraes
authors: MM
authors: Contti
authors: Luiz Gustavo
authors: LG
authors: Modeli de Andrade
authors: José Roberto
authors: JR
authors: Maiello
authors: Fernando Antonio
authors: FA
authors: Almeida
authors: Luis Cuadrado
authors: LC
authors: Martin
mesh_terms: D000465:Algorithms; D003324:Coronary Artery Disease / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D006435:Renal Dialysis; D012189:Retrospective Studies
keywords: Chronic renal failure; cardiovascular disease; coronary angiography; coronary artery disease; renal transplantation