title: Could hantavirus circulation superpose areas of highly endemic vaccinia virus outbreaks? A retrospective seroepidemiological study in State of Minas Gerais.
abstract: BACKGROUND
  Hantavirus infections have been described in several regions in Brazil through seroepidemiological studies. Usually, populations are associated with rural and wild environment mainly due to close contact to species of Sigmodontinae rodents, considered hantavirus reservoirs.
  
  
  METHODS
  A retrospective serosurvey was conducted to access the hantavirus seroprevalence in people living in regions affected by bovine vaccinia outbreaks.
  
  
  RESULTS
  Sera from 53 patients were analyzed and none of them presented anti-hantavirus IgG antibodies.
  
  
  CONCLUSIONS
  This study presents an opportunity to analyze seronegativity despite close and recurrent contact with known hantavirus reservoirs. Aspects of hantavirus and bovine vaccinia emergence are also discussed.
authors: Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BRAZIL.
authors: Giliane de Souza
authors: Gde S
authors: Trindade
authors: Instituto de Tecnologia em Imunobiológicos, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brasil.
authors: André Tavares da Silva
authors: AT
authors: Fernandes
authors: Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BRAZIL.
authors: Galileu Barbosa
authors: GB
authors: Costa
authors: Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BRAZIL.
authors: Poliana de Oliveira
authors: Pde O
authors: Figueiredo
authors: Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BRAZIL.
authors: Jônatas Santos
authors: JS
authors: Abrahão
authors: Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BRAZIL.
authors: Erna Geessien
authors: EG
authors: Kroon
authors: Centro de Pesquisa em Virologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
authors: Luiz Tadeu Moraes
authors: LT
authors: Figueiredo
authors: Laboratório de Virologia Básica e Aplicada, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, BRAZIL.
authors: Flávio Guimarães da
authors: FG
authors: Fonseca
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001938:Brazil / Q000453:epidemiology; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology*; D004196:Disease Outbreaks; D004197:Disease Reservoirs / Q000821:virology; D005260:Female; D006476:Orthohantavirus / Q000276:immunology*; D018778:Hantavirus Infections / Q000453:epidemiology*; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012424:Rural Population; D016036:Seroepidemiologic Studies; D016205:Sigmodontinae / Q000145:classification / Q000821:virology; D014615:Vaccinia / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary*; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral