title: Total synthesis of the proposed structure of a polyketide from Phialomyces macrosporus.
abstract: Total synthesis of the proposed structure of a polyketide isolated from Phialomyces macrosporus is described. The synthesis involved chemoselective epoxidation, regioselective epoxide ring opening, chemo- and diastereoselective dihydroxylation, and vinylation of lactone accompanied by the formation of a furan ring.
authors: School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan. itohisa@toyaku.ac.jp.
authors: Hideki
authors: H
authors: Abe
authors: Satoko
authors: S
authors: Itaya
authors: Kei
authors: K
authors: Sasaki
authors: Toyoharu
authors: T
authors: Kobayashi
authors: Hisanaka
authors: H
authors: Ito
mesh_terms: D001203:Ascomycota / Q000737:chemistry*; D015394:Molecular Structure; D061065:Polyketides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D061065:Polyketides