title: Results of kidney transplantation from deceased donors with acute kidney injury.
abstract: BACKGROUND
  Different strategies have been initiated to shorten the waiting list time to receive a kidney transplant. Donors with acute kidney injury (AKI) may be a new option.
  
  
  METHODS
  Fifty-nine patients received a kidney transplant from an AKI donor defined as having serum creatinine >2 mg/dL at the time of organ procurement. They were compared with a transplant group with normal kidney function defined as creatinine <1.5 mg/dL organ procurement in the same time period, paired by donor and recipient age (control group). Initial evolution, at 1 year, and at the end of the follow-up were evaluated.
  
  
  RESULTS
  The AKI donor group had greater delayed graft function (68% versus 36%, P < .01). Graft and recipient survival were similar in both groups at 1 year (92% versus 88%, P = NS; 97% versus 98%, P = NS) and at the end of follow-up (66% versus 66%, P = NS; 90% versus 88%, P = NS). Serum creatinine at 1 year and at the end of the follow-up did not show any differences (1.4 ± 0.5 versus 1.4 ± 0.7 mg/dL, P = NS; 1.4 ± 0.5 versus 1.6 ± 0.9 mg/dL, P = NS).
  
  
  CONCLUSIONS
  The transplants from donors with AKI showed greater incidence of delayed graft function, but this did not affect the short- or long-term prognosis of the graft or recipient. This type of donor may be a source of acceptable kidneys.
authors: Hospital 12 de Octubre, Madrid, Spain. Electronic address: mmgmolina@hotmail.com.
authors: M
authors: M
authors: Molina
authors: Hospital 12 de Octubre, Madrid, Spain.
authors: J
authors: J
authors: Apaza
authors: Hospital 12 de Octubre, Madrid, Spain.
authors: E
authors: E
authors: González Monte
authors: Hospital 12 de Octubre, Madrid, Spain.
authors: E
authors: E
authors: Gutiérrez Martínez
authors: Hospital 12 de Octubre, Madrid, Spain.
authors: A M
authors: AM
authors: Sevillano
authors: Hospital San Pedro de Alcántara, Cáceres, Spain.
authors: J P
authors: JP
authors: Marín
authors: Hospital 12 de Octubre, Madrid, Spain.
authors: N
authors: N
authors: Polanco
authors: Hospital 12 de Octubre, Madrid, Spain.
authors: A
authors: A
authors: Hernández
authors: Hospital 12 de Octubre, Madrid, Spain.
authors: M
authors: M
authors: Praga
authors: Hospital 12 de Octubre, Madrid, Spain.
authors: A
authors: A
authors: Andrés
mesh_terms: D058186:Acute Kidney Injury; D000328:Adult; D000368:Aged; D002102:Cadaver; D003404:Creatinine / Q000097:blood; D051799:Delayed Graft Function / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D005260:Female; D006085:Graft Survival; D006801:Humans; D015994:Incidence; D007668:Kidney / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D009927:Tissue and Organ Procurement; D016896:Treatment Outcome
chemical_list: D003404:Creatinine