title: Psychological features in patients with and without irritable bowel syndrome: A case-control study using Symptom Checklist-90-Revised.
abstract: BACKGROUND
  Recent studies have demonstrated that a high proportion of irritable bowel syndrome (IBS) patients shows an association with psychological factors. A few studies were conducted on the investigation of psychological features of IBS patients in Iran.
  
  
  OBJECTIVE
  We aimed to evaluate the relationship of psychological distress with IBS in outpatient subjects.
  
  
  METHODS
  A total of 153 consecutive outpatients met Rome III criteria, and 163 controls were interred to study and invited to complete the Symptom Checklist-90-Revised (SCL-90-R) instrument in order to assessment of psychological distress.
  
  
  METHODS
  Univariate (t-test and Chi-square) and multivariate (logistic regression) methods were used for data analysis.
  
  
  RESULTS
  A significant association of IBS with all nine subscale and three global indices including global severity index (GSI), positive symptom distress index (PSDI), and positive symptom total (PST) of the SCL-90-R were detected. Patients with IBS reported significantly higher levels of poor appetite, trouble falling asleep, thoughts of death or dying, early morning awakening, disturbed sleep, and feelings of guilt compared to the controls. Multivariate analysis indicated that interpersonal sensitivity, somatization, paranoid ideation, depression and phobic anxiety subscales, and PST, PSDI, and GSI global indices were significantly associated with IBS (age, gender, educational level, marital status, employment status, smoking, alcohol use, and body mass index).
  
  
  CONCLUSIONS
  Psychological features are strongly associated with IBS; notably, interpersonal sensitivity, somatization, paranoid ideation, depression, phobic anxiety, and all global indices including PST, PSDI, and GSI is significantly associated with. Hence, the appropriate psychological assessment in these patients is critically important.
authors: Department of Psychiatry, University of Social Welfare and Rehabilitation Science, Tehran, Iran.
authors: Fadai
authors: F
authors: Farbod
authors: Department of Psychiatry, University of Social Welfare and Rehabilitation Science, Tehran, Iran.
authors: Neda
authors: N
authors: Farzaneh
authors: Department of Health System Research, Research Institute for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors: Moghimi-Dehkordi
authors: MD
authors: Bijan
authors: Department of Liver Disease, Research Institute for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors: Ghobakhlou
authors: G
authors: Mehdi
authors: Department of Liver Disease, Research Institute for Gastroenterology and Liver Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors: Naderi
authors: N
authors: Nosratollah
keywords: Global severity index; Symptom Checklist-90-Revised; irritable bowel syndrome; psychological distress
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