title: Fabrication of a novel electrospun molecularly imprinted nanomembrane coupled with high-performance liquid chromatography for the selective separation and determination of acesulfame.
abstract: A novel in situ molecularly imprinted sol-gel nanomembrane using nylon 6 as backbone was prepared by the electrospinning technique and coupled on-line with high-performance liquid chromatography. The prepared electrospun membrane exhibited extensive selectivity toward acesulfame in the presence of some selected sweeteners in a beverage sample, while the porosity and mechanical stability remained. The prepared electrospun membrane could be applied for 35 consequence extractions without a significant change in extraction recovery, swelling, and flooding. To achieve the best condition and efficiency for on-line extraction, the effect of influential parameters was investigated. The limit of detection (signal/noise = 3:1) and limit of quantification (signal/noise = 10:1) were 0.6 and 2.0 ng/mL for acesulfame in the beverage samples, respectively. The linearity for the acesulfame was in the range of 2.0-250 ng/mL in beverage samples. The coefficients of determination values were ≥0.997 for all runs. The extraction recoveries of acesulfame in the beverage samples were between 80 and 85%.
authors: Department of Chemistry, Amirkabir University of Technology, Hafez, Tehran, Iran.
authors: Mohammad Mahdi
authors: MM
authors: Moein
authors: Mehran
authors: M
authors: Javanbakht
authors: Mohammad
authors: M
authors: Karimi
authors: Behrouz
authors: B
authors: Akbari-adergani
mesh_terms: D000327:Adsorption; D002138:Calibration; D002623:Chemistry Techniques, Analytical; D002851:Chromatography, High Pressure Liquid; D004563:Electrochemistry; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D008567:Membranes, Artificial; D008855:Microscopy, Electron, Scanning; D054802:Molecular Imprinting; D049329:Nanostructures / Q000737:chemistry*; D044367:Phase Transition; D016062:Porosity; D015203:Reproducibility of Results; D012492:Salts / Q000737:chemistry; D013314:Stress, Mechanical; D013843:Thiazines / Q000737:chemistry*
chemical_list: D008567:Membranes, Artificial; D012492:Salts; D013843:Thiazines; C006362:acetosulfame
keywords: Acesulfame; Beverages; Electrospinning; Molecularly imprinted polymers; Sol-gel processes