title: Urethral strictures in men with neurogenic lower urinary tract dysfunction using intermittent catheterization for bladder evacuation.
abstract: METHODS
  Retrospective investigation.
  
  
  OBJECTIVE
  To investigate the occurrence, characteristics and clinical consequences of urethral strictures in men with neurogenic lower urinary tract dysfunction (NLUTD) using intermittent catheterization (IC) for bladder evacuation.
  
  
  METHODS
  Spinal cord injury rehabilitation center.
  
  
  METHODS
  The patient database was screened for men with NLUTD who had presented for a routine video-urodynamic investigation between 2008 and 2012. Patient characteristics, bladder diary details, the occurrence of urethral strictures and performed urethrotomy procedures were collected from patient charts. Urethral strictures were classified using the Wiegand scoring system modified for men with NLUTD.
  
  
  RESULTS
  The occurrence rate of urethral strictures (that is, 25% confidence interval (CI) 21-30%) was significantly (P=0.0001) higher in men using IC (n=415) than in men using other bladder evacuation methods (that is, 14% CI 11-17%) (n=629). Urethral strictures had occurred after a median 5.9 years (range 0.5-48.9 years) of IC. There was no significant (P>0.08) effect of tetraplegia or catheter type on the stricture occurrence rate. Approximately one-third of the men suffering from urethral strictures underwent internal urethrotomies. The radiographic stricture severity score was not associated with the need for surgical correction of the stricture. The radiographic recurrence rate of urethral strictures in operated men was 100%, a median 14 years after the first urethrotomy.
  
  
  CONCLUSIONS
  The occurrence rate of urethral strictures is significantly higher in men using IC than in men using other bladder evacuation methods. Every fourth men using IC may be affected by urethral strictures. However, only every third stricture may require a surgical intervention.
authors: Clinical Trial Unit, Swiss Paraplegic Centre, Nottwil, Switzerland.
authors: J
authors: J
authors: Krebs
authors: Neurourology, Schweizer Paraplegiker Zentrum, Swiss Paraplegic Centre, Nottwil, Switzerland.
authors: J
authors: J
authors: Wöllner
authors: Neurourology, Schweizer Paraplegiker Zentrum, Swiss Paraplegic Centre, Nottwil, Switzerland.
authors: J
authors: J
authors: Pannek
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D011782:Quadriplegia / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D011859:Radiography; D012008:Recurrence; D012047:Rehabilitation Centers; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013119:Spinal Cord Injuries / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000628:therapy*; D014525:Urethral Stricture / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D014546:Urinary Catheterization / Q000009:adverse effects*; D062885:Urinary Catheters; D055815:Young Adult
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