title: FH-deficient cancers depend on ABL1-mediated metabolic adaptation.
mesh_terms: D002292:Carcinoma, Renal Cell / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism*; D005649:Fumarate Hydratase / Q000172:deficiency* / Q000235:genetics / Q000378:metabolism; D016044:Fusion Proteins, bcr-abl / Q000378:metabolism; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism*; D008661:Metabolism, Inborn Errors / Q000235:genetics / Q000378:metabolism*; D009123:Muscle Hypotonia / Q000235:genetics / Q000378:metabolism*; D051267:NF-E2-Related Factor 2 / Q000378:metabolism; D018384:Oxidative Stress / Q000502:physiology; D011596:Psychomotor Disorders / Q000235:genetics / Q000378:metabolism*
chemical_list: C581634:BCR-ABL1 fusion protein, human; D051267:NF-E2-Related Factor 2; C495635:NFE2L2 protein, human; D016044:Fusion Proteins, bcr-abl; D005649:Fumarate Hydratase