title: [Antiadhesive potencial of Rhodococcus erythropolis IMB Ac-5017 biosurfactants].
abstract: The effect of Rhodococcus erythropolis IMB Ac-5017 biosurfactants (surface-active substances, SAS) with different degree of purification on attachment of bacteria (Escherichia coli IEM-1, Bacillus subtilis BT-2, Proteus vulgaris BT-1, Staphylococcus aureus BMC-1, Pseudomonas aeruginosa P-55, Enterobacter cloacae AC-22, Erwinia aroidaeae B-433), yeasts (Candida albicans D-6) and fungi (Aspergillus niger P-3, Fusarium culmorum T-7) to the abiotic surfaces (glass, plastic, ceramics, steel, linoleum) was studied. The dependence of microorganisms adhesion on degree of SAS purification (supernatant, purified SAS solution), SAS concentration (0,04-1,25 mg/ml), type of surface and test-cultures was established. The adhesion of majority investigated bacterial cells after treatment of abiotic surfaces with supernatant of cultural liquid with SAS concentration 0,06-0,25 mg/ml was on the average 20-45, yeasts C. albicans D-6--30-75% and was less than that purified SAS solution with the same concentration. Higher antiadhesive activity of supernatant as compared to purified SAS solution testifies to possibility of exception of the expensive stage of isolation and purification at obtaining of preparations with antiadhesive properties.
authors: T P
authors: TP
authors: Pirog
authors: N A
authors: NA
authors: Gritsenko
authors: A D
authors: AD
authors: Konon
authors: T A
authors: TA
authors: Shevchuk
authors: G A
authors: GA
authors: Iutinskaia
mesh_terms: D001234:Aspergillus niger / Q000187:drug effects / Q000502:physiology; D001412:Bacillus subtilis / Q000187:drug effects / Q000502:physiology; D001422:Bacterial Adhesion / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects / Q000502:physiology; D017077:Culture Media, Conditioned / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D016972:Enterobacter cloacae / Q000187:drug effects / Q000502:physiology; D004885:Erwinia / Q000187:drug effects / Q000502:physiology; D004926:Escherichia coli / Q000187:drug effects / Q000502:physiology; D005670:Fusarium / Q000187:drug effects / Q000502:physiology; D011514:Proteus vulgaris / Q000187:drug effects / Q000502:physiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000502:physiology; D012240:Rhodococcus / Q000737:chemistry* / Q000378:metabolism; D013211:Staphylococcus aureus / Q000187:drug effects / Q000502:physiology; D013499:Surface Properties; D013501:Surface-Active Agents / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology*
chemical_list: D017077:Culture Media, Conditioned; D013501:Surface-Active Agents