title: Mediators involved in the relation between depressive symptoms and weight status in female adolescents and young adults.
abstract: Depression may be a risk factor for overweight status, but mechanisms involved in this relationship are unclear. This study explored behavioral factors involved in the relationship between adolescent depression symptoms and adult overweight status. A population-based cohort of female participants in Project EAT (n=1035) was followed over 10 years and reported on psychological functioning, weight status and eating and activity patterns in early/middle adolescence (1999=Time 1; T1), middle adolescence/early young adulthood (2004=Time 2; T2) and early/middle young adulthood (2009=Time 3; T3). Structural equation models were fit which included T1 depression scores predicting overweight status at T3, with T2 fruit and vegetable consumption, moderate-to-vigorous physical activity and binge eating examined as mediators. There were small but significant effects of T1 depression scores predicting an increased likelihood of T3 overweight status (standardized estimate=0.038; P=0.007), and of T2 binge eating mediating the relation between T1 depression and T3 overweight status (standardized indirect effect estimate=0.036; P=0.009). Binge eating may be one pathway to overweight among depressed females, suggesting that recognition and treatment of eating pathology in individuals with depression may help prevent overweight. Examination of other behavioral (and non-behavioral) factors explaining the relationship between depression and overweight is warranted.
authors: Department of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, IL, USA.
authors: A B
authors: AB
authors: Goldschmidt
authors: Department of Biostatistics, Columbia University, New York, NY, USA.
authors: M M
authors: MM
authors: Wall
authors: Department of Biostatistics, Columbia University, New York, NY, USA.
authors: T-H J
authors: TH
authors: Choo
authors: Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
authors: N I
authors: NI
authors: Larson
authors: Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
authors: D
authors: D
authors: Neumark-Sztainer
mesh_terms: D000293:Adolescent; D017195:Adolescent Nutritional Physiological Phenomena; D001835:Body Weight; D003863:Depression / Q000150:complications* / Q000453:epidemiology; D005247:Feeding Behavior / Q000523:psychology*; D005260:Female; D006801:Humans; D008910:Minnesota / Q000453:epidemiology; D009765:Obesity / Q000453:epidemiology / Q000517:prevention & control / Q000523:psychology*; D012307:Risk Factors; D012649:Self Concept; D055815:Young Adult
references: Adv Data. 2000 Jun 8;(314):1-27
references: 11183293
references: Int J Eat Disord. 1994 Sep;16(2):147-57
references: 7987349
references: Prev Med. 2004 Jun;38(6):865-75
references: 15193910
references: Arch Gen Psychiatry. 1982 Oct;39(10):1205-12
references: 7125850
references: Prev Med. 1997 Nov-Dec;26(6):808-16
references: 9388792
references: Obes Res. 1993 Jul;1(4):306-24
references: 16350580
references: Int J Geriatr Psychiatry. 2010 May;25(5):466-75
references: 19711303
references: J Clin Psychiatry. 2010 Oct;71(10):1259-72
references: 21062615
references: Obes Rev. 2011 May;12(5):e438-53
references: 21414128
references: Psychol Bull. 2011 Jul;137(4):660-81
references: 21574678
references: Curr Opin Clin Nutr Metab Care. 2011 Sep;14(5):419-24
references: 21832897
references: Lancet. 2011 Aug 27;378(9793):815-25
references: 21872750
references: Behav Pharmacol. 2012 Sep;23(5-6):442-60
references: 22854304
references: Ann Epidemiol. 2013 Jan;23(1):25-30
references: 23176784
references: JAMA Pediatr. 2013 Feb;167(2):149-55
references: 23229786
references: Am J Public Health. 2002 May;92(5):844-51
references: 11988458
references: Can J Appl Sport Sci. 1985 Sep;10(3):141-6
references: 4053261
references: Med Sci Sports Exerc. 1993 Jan;25(1):99-108
references: 8423762
references: Int J Behav Nutr Phys Act. 2013;10:37
references: 23531253