title: Study of the prevalence of Capillaria hepatica in humans and rodents in an urban area of the city of Porto Velho, Rondônia, Brazil.
abstract: BACKGROUND
  Hepatic capillariosis, caused by Capillaria hepatica (Calodium hepaticum) (Bancroft, 1893), Travassos, 1915 (Nematoda, Trichinelloidea, Capillariidae), is a common zoonosis in rodents but is rare in humans. Seventy-two cases in humans have been reported worldwide since the first case was described by MACARTHUR in 192417,27. This study aimed to determine the prevalence of Capillaria hepatica in humans and rodents in an urban area of Porto Velho, the capital of Rondônia, in Brazil.
  
  
  METHODS
  After conducting a census of the area, 490 residents were randomly selected, and, after signing a term of consent, provided blood samples that were screened for anti-Capillaria hepatica antibodies. Simultaneously, rats were captured to assess the prevalence of this parasite in rodents by histopathological examination in liver sections.
  
  
  RESULTS
  A prevalence of 1.8% was found among residents who had specific antibodies at a dilution of 1:150, indicating exposure to parasite eggs; 0.8% of the subjects also had positive titers at a dilution of 1:400, indicating true infection. The prevalence in rats was 2%.
  
  
  CONCLUSIONS
  The prevalence of infection with this parasite among humans and rats was low. While the prevalence encountered among humans was within the limits reported in the literature, the prevalence among rodents was much lower.
authors: Faculdade São Lucas. R. Alexandre Guimarães, Porto Velho, Rondônia, Brazil.
authors: Elierson José Gomes da
authors: EJ
authors: Rocha
authors: Faculdade São Lucas. R. Alexandre Guimarães, Porto Velho, Rondônia, Brazil.
authors: Sérgio de Almeida
authors: Sde A
authors: Basano
authors: Laboratório de Patologia Experimental, Centro de Pesquisas Gonçalo Moniz, CPqGM/FIOCRUZ, Salvador, Bahia, Brazil.
authors: Márcia Maria de
authors: MM
authors: Souza
authors: Laboratório Central de Saúde Pública de Rondônia, Porto Velho, Rondônia, Brazil.
authors: Eduardo Resende
authors: ER
authors: Honda
authors: Laboratório de Patologia Veterinária, Via L4 Norte s/n°, Hospital Universitário, UnB Universidade de Brasília, Campus Universitário Darcy Ribeiro, Brasília, DF, Brazil.
authors: Márcio Botelho de
authors: MB
authors: Castro
authors: Departamento de Clínica Médica Veterinária, CLIMEV. Faculdade de Agronomia e Medicina Veterinária, FAMEV, Universidade Federal de Mato Grosso/UFMT, Cuiabá, Mato Grosso, Brazil.
authors: Edson Moleta
authors: EM
authors: Colodel
authors: Faculdade São Lucas. R. Alexandre Guimarães, Porto Velho, Rondônia, Brazil.
authors: Jéssica Carolinne Damasceno
authors: JC
authors: e Silva
authors: Faculdade São Lucas. R. Alexandre Guimarães, Porto Velho, Rondônia, Brazil.
authors: Lauro Prado
authors: LP
authors: Barros
authors: Faculdade São Lucas. R. Alexandre Guimarães, Porto Velho, Rondônia, Brazil.
authors: Elisa Sousa
authors: ES
authors: Rodrigues
authors: University of Sao Paulo, Rondonia, Brazil.
authors: Luís Marcelo Aranha
authors: LM
authors: Camargo
mesh_terms: D000818:Animals; D001938:Brazil / Q000453:epidemiology; D002195:Capillaria / Q000276:immunology*; D004197:Disease Reservoirs; D017189:Enoplida Infections / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D008109:Liver Diseases, Parasitic / Q000175:diagnosis / Q000453:epidemiology* / Q000469:parasitology; D015995:Prevalence; D051381:Rats; D012376:Rodent Diseases / Q000453:epidemiology / Q000469:parasitology*
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