title: Prevalence of hyposalivation in patients with systemic lupus erythematosus in a brazilian subpopulation.
abstract: Background. Systemic lupus erythematosus (SLE) is a chronic inflammatory, multisystem, and autoimmune disease. Objective. The aim of this study was to describe the prevalence of hyposalivation in SLE patients and evaluate factors associated. Methods. This is a cross-sectional study developed at the Cuiaba University General Hospital (UNIC-HGU), Mato Grosso, Brazil. The study population consisted of female SLE patients treated at this hospital from 06/2010 to 12/2012. Unstimulated salivary flow rates (SFRs) were measured. Descriptive and inferential analyses were performed in all cases using a significance level P < 0.05. Results. The results showed that 79% of patients with systemic lupus erythematosus suffered from hyposalivation and that the disease activity and age in years were the factors that resulted in statistically significant differences. Conclusion. The activity of the disease, age >27 years, and the drugs used were factors associated with hyposalivation, resulting in a statistically significant decrease in saliva production.
authors: Department of Oral Pathology, University of Cuiabá, Avenida Manoel José de Arruda 3.100 Jardim Europa, 78065-900 Cuiabá, MT, Brazil ; Department of Pathology, Federal Fluminense University, Rua Marquês do Paraná 303, No. 4 Andar do Prédio Principal, Sala 1, 24.033-900 Niterói, RJ, Brazil.
authors: Cristhiane Almeida
authors: CA
authors: Leite
authors: Department of Pediatrics, School of Medicine, Federal University of Mato Grosso, Avenida Fernando Corrêa da Costa 2367, Boa Esperança, 78060-900 Cuiabá, MT, Brazil.
authors: Marcial Francis
authors: MF
authors: Galera
authors: Department of Statistics, Institute of Exact Sciences, Federal University of Mato Grosso, Avenida Fernando Corrêa da Costa 2367, Boa Esperança, 78060-900 Cuiabá, MT, Brazil.
authors: Mariano Martínez
authors: MM
authors: Espinosa
authors: School of Dentistry, University of Cuiabá, Brazil Avenida Manoel José de Arruda 3.100, Jardim Europa, 78065-900 Cuiabá, MT, Brazil.
authors: Paulo Ricardo Teles
authors: PR
authors: de Lima
authors: Department of Rheumatology, University of Cuiabá, Avenida Manoel José de Arruda 3.100, Jardim Europa, 78065-900 Cuiabá, MT, Brazil.
authors: Vander
authors: V
authors: Fernandes
authors: Faculty of Dentistry, University of Cuiabá, Avenida Manoel José de Arruda 3.100, Jardim Europa, 78065-900 Cuiabá, MT, Brazil.
authors: Álvaro Henrique
authors: ÁH
authors: Borges
authors: Department of Pathology, Federal Fluminense University, Rua Marquês do Paraná 303, No. 4 Andar do Prédio Principal, Sala 1, 24.033-900 Niterói, RJ, Brazil.
authors: Eliane Pedra
authors: EP
authors: Dias
references: Arthritis Rheum. 1997 Sep;40(9):1725
references: 9324032
references: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Mar;103 Suppl:S57.e1-15
references: 17379156
references: Arthritis Rheum. 1991 Aug;34(8):937-44
references: 1859487
references: Gerodontology. 2003 Dec;20(2):64-77
references: 14697016
references: J Can Dent Assoc. 2007 Nov;73(9):823-8
references: 18028758
references: J Oral Pathol Med. 1999 Aug;28(7):317-22
references: 10432198
references: Ann Intern Med. 1974 Nov;81(5):577-83
references: 4138478
references: N Engl J Med. 2008 Feb 28;358(9):929-39
references: 18305268
references: J Rheumatol. 1990 Feb;17(2):201-4
references: 2319519
references: J Oral Pathol Med. 2007 Oct;36(9):524-7
references: 17850434
references: Br J Oral Maxillofac Surg. 1997 Apr;35(2):96-103
references: 9146866
references: Rheumatol Int. 2013 Dec;33(12):3079-82
references: 23274440
references: J Dent Res. 1994 Aug;73(8):1416-20
references: 8083437
references: Ann Rheum Dis. 2001 Dec;60(12):1103-9
references: 11709451
references: Lupus. 2010 Aug;19(9):1118-24
references: 20693206
references: Ann Rheum Dis. 1994 Oct;53(10 ):637-47
references: 7979575
references: Community Dent Oral Epidemiol. 2008 Dec;36(6):523-31
references: 18422708
references: Oral Surg Oral Med Oral Pathol. 1993 Jun;75(6):696-9
references: 7685874
references: Arthritis Rheum. 1992 Jun;35(6):630-40
references: 1599520
references: J Public Health Dent. 2006 Spring;66(2):152-8
references: 16711637
references: N Z Med J. 1977 Oct 26;86(598):374-6
references: 272546
references: J Am Dent Assoc. 2008 May;139 Suppl:35S-40S
references: 18460678
references: Drugs Aging. 1999 Aug;15(2):103-16
references: 10495070
references: J Cutan Pathol. 2007 Jul;34(7):558-64
references: 17576335
references: J Can Dent Assoc. 2006 Nov;72(9):841-6
references: 17109806
references: Aging (Milano). 1998 Oct;10(5):421-8
references: 9932146
references: Otolaryngol Pol. 2014 Jan-Feb;68(1):1-14
references: 24484943
references: Dent Clin North Am. 2005 Jan;49(1):127-41, ix
references: 15567365
references: J Dent Res. 1987 Feb;66 Spec No:648-53
references: 3476629
references: Br J Dermatol. 1989 Dec;121(6):727-41
references: 2611124
references: Lupus. 2012 Aug;21(9):969-77
references: 22453994
references: Oral Surg Oral Med Oral Pathol. 1988 Oct;66(4):451-8
references: 3186220
references: J Cutan Pathol. 2010 Apr;37(4):432-8
references: 19614726
references: Spec Care Dentist. 2011 Jul-Aug;31(4):123-8
references: 21729120
references: Rev Bras Reumatol. 2013 Nov-Dec;53(6):525-31
references: 24477731
references: J Evid Based Dent Pract. 2014 Jun;14 Suppl:87-94.e1
references: 24929593
references: Quintessence Int. 1990 Jun;21(6):461-5
references: 2243950
references: Oral Surg Oral Med Oral Pathol. 1982 Dec;54(6):635-9
references: 6961339
references: J Rheumatol. 1984 Feb;11(1):38-42
references: 6366226
references: Clin Dev Immunol. 2012;2012:715190
references: 22312407