title: Coding of movements in the motor cortex.
abstract: The issue of coding of movement in the motor cortex has recently acquired special significance due to its fundamental importance in neuroprosthetic applications. The challenge of controlling a prosthetic arm by processed motor cortical activity has opened a new era of research in applied medicine but has also provided an 'acid test' for hypotheses regarding coding of movement in the motor cortex. The successful decoding of movement information from the activity of motor cortical cells using their directional tuning and population coding has propelled successful neuroprosthetic applications and, at the same time, asserted the utility of those early discoveries, dating back to the early 1980s.
authors: Brain Sciences Center, Minneapolis Veterans Affairs Health Care System, Minneapolis, MN 55417, USA; Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA; Department of Neurology, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: omega@umn.edu.
authors: Apostolos P
authors: AP
authors: Georgopoulos
authors: Brain Sciences Center, Minneapolis Veterans Affairs Health Care System, Minneapolis, MN 55417, USA; Department of Neurology, University of Minnesota, Minneapolis, MN 55455, USA.
authors: Adam F
authors: AF
authors: Carpenter
mesh_terms: D000344:Afferent Pathways / Q000502:physiology; D018737:Hand Strength; D006801:Humans; D008954:Models, Biological; D009044:Motor Cortex / Q000166:cytology / Q000502:physiology*; D009068:Movement / Q000502:physiology*; D009474:Neurons / Q000502:physiology