title: Stemofurans X-Y from the roots of Stemona species from Laos.
abstract: Two new phenylbenzofuran-type stilbenoids named stemofurans X and Y (1, 2) were isolated from the roots of Stemona pierrei and S. tuberosa, respectively, together with ten known compounds. These compounds were stemanthrenes B-C (3, 4), (+)-syringaresinol (5), maistemonine (6), isomaistemonine (7) and sesamin (8) from S. pierrei, and stemophenanthrenes A-C (9-11) and isopinosylvin A (12) from S. tuberosa. Stemofurans X-Y (1, 2) showed moderate cytotoxicity against the four cancer cell lines KB (human epidermal carcinoma), MCF7 (human breast carcinoma), SK-LU-1 (human lung carcinoma), and Hep-G2 (hepatocellular carcinoma).
authors: Dang Ngoc
authors: DN
authors: Quang
authors: Vong Anatha
authors: VA
authors: Khamko
authors: Nguyen Thi
authors: NT
authors: Trang
authors: Lam Thi Hai
authors: LT
authors: Yen
authors: Pham Huu
authors: PH
authors: Dien
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D045744:Cell Line, Tumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D018517:Plant Roots / Q000737:chemistry; D041901:Stemonaceae / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D001572:Benzofurans; C000595945:stemofuran X; C000595946:stemofuran Y