title: Percutaneous endoscopic gastrostomy versus nasogastric feeding in older individuals with non-stroke dysphagia: a systematic review.
abstract: OBJECTIVE
  The objective of this systematic review was to evaluate existing studies on the effectiveness of percutaneous endoscopic gastrostomy (PEG) feeding compared to nasogastric (NG) feeding for patients with non-stroke related dysphagia.
  
  
  METHODS
  We searched Ovid MEDLINE, EMBASE, the Cochrane Library, Web of Science and PubMed databases through to December 2013 using the terms "percutaneous endoscopic gastrostomy", "gastrostomy", "PEG", "nasogastric", "nasogastric tube", "nasogastric feeding" and "intubation". We included randomized controlled trials (RCTs) and non-RCTs which compared PEG with NG feeding in individuals with non-stroke dysphagia.
  
  
  RESULTS
  9 studies involving 847 participants were included in the final analysis, including two randomized trials. Pooled analysis indicated no significant difference in the risk of pneumonia [relative risk (RR) = 1.18, 95% confidence interval (CI) = 0.87-1.60] and overall complications [relative risk (RR) = 0.80, 95% confidence interval (CI) = 0.63-1.02] between PEG and NG feeding. A meta-analysis was not possible for mortality and nutritional outcomes, but three studies suggested improved mortality outcomes with PEG feeding while two out of three studies reported PEG feeding to be better from a nutritional perspective.
  
  
  CONCLUSIONS
  Firm conclusions could not be derived on whether PEG feeding is beneficial over NG feeding in older persons with non-stroke dysphagia, as previously published literature were unclear or had a high risk of bias. A well-designed and adequately powered RCT, which includes carer strain and quality of life as outcome measures is therefore urgently needed.
authors: M.P. Tan, Department of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia, mptan@ummc.edu.my.
authors: M H
authors: MH
authors: Jaafar
authors: S
authors: S
authors: Mahadeva
authors: K
authors: K
authors: Morgan
authors: M P
authors: MP
authors: Tan
mesh_terms: D000368:Aged; D002986:Clinical Trials as Topic; D003680:Deglutition Disorders / Q000150:complications / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D004750:Enteral Nutrition / Q000009:adverse effects; D005774:Gastrostomy / Q000009:adverse effects; D015577:Geriatric Assessment; D006801:Humans; D007441:Intubation, Gastrointestinal / Q000009:adverse effects; D008875:Middle Aged; D015596:Nutrition Assessment; D011014:Pneumonia / Q000150:complications / Q000209:etiology; D016896:Treatment Outcome
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