title: A questionnaire study on the knowledge, attitude, and the practice of pharmacovigilance among the healthcare professionals in a teaching hospital in South India.
abstract: OBJECTIVE
  The primary objective of this study was to evaluate the knowledge, attitude, and practices (KAP) of the healthcare professionals about pharmacovigilance in Dhanalakshmi Srinivasan Medical College and Hospital (DSMCH), Perambalur (Tamil Nadu), a tertiary care teaching hospital. The second primary objective was to assess the causation of underreporting of adverse drug reactions (ADRs) as it needs to be well-assessed in India. The secondary objective was to compare the findings of this study with the results of the published studies from India on evaluation of the KAP of pharmacovigilance among healthcare professional.
  
  
  METHODS
  A cross-sectional study was carried out using a pretested questionnaire. The questionnaire was designed to assess the KAP regarding pharmacovigilance. The healthcare professionals (doctors, nurses, and pharmacists) working in the DSMCH, Perambalur (Tamil Nadu) during the study period were included. Only those who gave their consent to participate were included in the study. The data was analyzed by using the Statistical Package for Social Sciences (SPSS) statistical software, version 16.
  
  
  RESULTS
  One hundred and fifty pretested questionnaires were distributed among the healthcare professionals and 101 responded. 62.4% healthcare workers gave correct response regarding the definition of pharmacovigilance. 75.2% of healthcare workers were aware regarding the existence of a National Pharmacovigilance Program of India. 69.3% healthcare professional agreed that ADR reporting is a professional obligation for them. Among the participants, 64.4% have experienced ADRs in patients, but only 22.8% have ever reported ADR to pharmacovigilance center. Unfortunately only 53.5% healthcare workers have been trained for reporting adverse reactions. But, 97% healthcare professionals agreed that reporting of ADR is necessary and 92.1% were of the view that pharmacovigilance should be taught in detail to healthcare professional.
  
  
  CONCLUSIONS
  This study demonstrated that knowledge and attitude towards pharmacovigilance is gradually improving among healthcare professionals, but unfortunately the actual practice of ADR reporting is still deficient among them.
authors: Department of Pharmacology, Dhanalakshmi Srinivasan Medical College and Hospital, Siruvachur, Perambalur, Tamil Nadu, India.
authors: Sandeep Kumar
authors: SK
authors: Gupta
authors: Department of Pharmacology, Dhanalakshmi Srinivasan Medical College and Hospital, Siruvachur, Perambalur, Tamil Nadu, India.
authors: Roopa P
authors: RP
authors: Nayak
authors: Dhanalakshmi Srinivasan Medical College and Hospital, Siruvachur, Perambalur, Tamil Nadu, India.
authors: R
authors: R
authors: Shivaranjani
authors: Department of Pharmacology, Dhanalakshmi Srinivasan Medical College and Hospital, Siruvachur, Perambalur, Tamil Nadu, India.
authors: Surendra Kumar
authors: SK
authors: Vidyarthi
keywords: Adverse drug reactions; attitude; knowledge; pharmacovigilance; practice; spontaneous reporting; under-reporting
references: Indian J Pharmacol. 2008 Feb;40(Suppl 1):S31-4
references: 21369412
references: Yonsei Med J. 2012 Sep;53(5):1022-7
references: 22869488
references: Eur J Clin Pharmacol. 2006 May;62(5):381-5
references: 16572320
references: Int J Risk Saf Med. 2011;23(4):227-32
references: 22156087
references: J Nat Sci Biol Med. 2013 Jan;4(1):191-6
references: 23633861
references: Indian J Med Sci. 2012 Mar-Apr;66(3-4):55-61
references: 23603621
references: Eur J Clin Pharmacol. 2013 Feb;69(2):237-44
references: 22706618
references: J Clin Diagn Res. 2013 Jan;7(1):97-9
references: 23449824
references: Br J Clin Pharmacol. 2009 May;67(5):558-64
references: 19552751
references: Perspect Clin Res. 2011 Oct;2(4):129-36
references: 22145123
references: Chin Med J (Engl). 2004 Jun;117(6):856-61
references: 15198887
references: Indian J Pharmacol. 2012 Nov-Dec;44(6):699-703
references: 23248397
references: Ther Clin Risk Manag. 2012;8:307-12
references: 22767994
references: J Clin Pharmacol. 2013 Nov;53(11):1220-5
references: 23852627
references: Curr Drug Saf. 2012 Nov 1;7(5):384-8
references: 23150923
references: Perspect Clin Res. 2012 Jul;3(3):90-4
references: 23125959