title: Botanicals: an alternative remedy to radiotherapy-induced dysuria.
abstract: Everyday, many patients get radiotherapy for prostatic, rectal, uterine cervix and other pelvic organs cancer. Dysuria is common in pelvic, especially prostate radiotherapy, but there is not any established and confirmed treatment for this therapeutic side effect. Therefore, an alternative therapeutic method, using herbal preparation, may be an effective solution. This study seeks a defensible suggestion in Iranian Traditional Medicine (ITM). In ITM, a few medicinal herbs such as Plantago psyllium, Cydonia oblonga, Portulaca oleracea and some species of Malvaceae and Cucurbitaceae family are indicated in treating dysuria secondary to urethral moisturizing layer defect and inflammatory disorders. Most of these herbs have mucilaginous characteristics and tissue regeneration ability. This choice can be an appropriate one for radiotherapy-induced dysuria as it is produced by a similar pathophysiology with bladder cell layer injury and urethritis. Pharmacological properties such as anti-oxidant, anti-inflammatory, and anti-ulcerogenic activity of the offered herbs make its use justifiable. In lack of sufficient clinical trials to clarify the clinical outcome, further clinical investigation seems to be necessary.
authors: Department of Traditional Iranian Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran.
authors: Amir Mohammad
authors: AM
authors: Jaladat
authors: Department of Traditional Iranian Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran.
authors: Fatemeh
authors: F
authors: Atarzadeh
authors: Department of Traditional Iranian Medicine and Traditional Medicine & Pharmacy Research Center, Faculty of Traditional Medicine, Tehran University of Medical Science, Tehran, Iran.
authors: Hossein
authors: H
authors: Rezaeizadeh
authors: Department of Radiation Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors: Bahram
authors: B
authors: Mofid
authors: Department of Radiation Oncology, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Ahmad
authors: A
authors: Mosalaie
authors: Department of Radiation Oncology, Cancer Institute, Imam Khomeini Hospital, Tehran, Iran.
authors: Farshid
authors: F
authors: Farhan
authors: Department of Traditional Iranian Medicine and Pharmacy Research Center, Faculty of traditional Medicine, Tehran University of Medical Science, Tehran, Iran. Electronic address: amin@tums.ac.ir.
authors: Gholamreza
authors: G
authors: Amin
mesh_terms: D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D053159:Dysuria / Q000188:drug therapy*; D006801:Humans; D008519:Medicine, Traditional / Q000379:methods; D008517:Phytotherapy / Q000379:methods; D010946:Plants, Medicinal; D011878:Radiotherapy / Q000009:adverse effects*
chemical_list: D004365:Drugs, Chinese Herbal
keywords: Botanicals; Dysuria; Herbal remedies; Iranian traditional medicine; Prostate cancer; Radiotherapy