title: The Western Denmark Cardiac Computed Tomography Registry: a review and validation study.
abstract: BACKGROUND
  As a subregistry to the Western Denmark Heart Registry (WDHR), the Western Denmark Cardiac Computed Tomography Registry (WDHR-CCTR) is a clinical database established in 2008 to monitor and improve the quality of cardiac computed tomography (CT) in Western Denmark.
  
  
  OBJECTIVE
  We examined the content, data quality, and research potential of the WDHR-CCTR.
  
  
  METHODS
  We retrieved 2008-2012 data to examine the 1) content; 2) completeness of procedure registration using the Danish National Patient Registry as reference; 3) completeness of variable registration comparing observed vs expected numbers; and 4) positive predictive values as well as negative predictive values of 19 main patient and procedure variables.
  
  
  RESULTS
  By December 31, 2012, almost 22,000 cardiac CTs with up to 40 variables for each procedure have been registered. Of these, 87% were coronary CT angiography performed in patients with symptoms indicative of coronary artery disease. Compared with the Danish National Patient Registry, the overall procedure completeness was 72%. However, an additional medical record review of 282 patients registered in the Danish National Patient Registry, but not in the WDHR-CCTR, showed that coronary CT angiographies accounted for only 23% of all nonregistered cardiac CTs, indicating >90% completeness of coronary CT angiographies in the WDHR-CCTR. The completeness of individual variables varied substantially (range: 0%-100%), but was >85% for more than 70% of all variables. Using medical record review of 250 randomly selected patients as reference standard, the positive predictive value for the 19 variables ranged from 89% to 100% (overall 97%), whereas the negative predictive value ranged from 97% to 100% (overall 99%). Stratification by center status showed consistently high positive and negative predictive values for both university (96%/99%) and nonuniversity centers (97%/99%).
  
  
  CONCLUSIONS
  WDHR-CCTR provides ongoing prospective registration of all cardiac CTs performed in Western Denmark since 2008. Overall, the registry data have a high degree of completeness and validity, making it a valuable tool for clinical epidemiological research.
authors: Department of Cardiology, Lillbaelt Hospital-Vejle, Vejle, Denmark.
authors: Lene Hüche
authors: LH
authors: Nielsen
authors: Department of Cardiology Aarhus University Hospital-Skejby, Aarhus, Denmark.
authors: Bjarne Linde
authors: BL
authors: Nørgaard
authors: Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark.
authors: Hans Henrik
authors: HH
authors: Tilsted
authors: Department of Cardiology, Hospital of Southwestern Denmark-Esbjerg, Esbjerg, Denmark.
authors: Niels Peter
authors: NP
authors: Sand
authors: Department of Cardiology Aarhus University Hospital-Skejby, Aarhus, Denmark.
authors: Jesper Møller
authors: JM
authors: Jensen
authors: Department of Cardiology, Regional Hospital Herning, Herning, Denmark.
authors: Morten
authors: M
authors: Bøttcher
authors: Department of Cardiology, Odense University Hospital, Odense, Denmark.
authors: Axel C
authors: AC
authors: Diederichsen
authors: Department of Cardiology, Odense University Hospital-Svendborg, Svendborg, Denmark.
authors: Jess
authors: J
authors: Lambrechtsen
authors: Department of Cardiology, Regional Hospital Silkeborg, Silkeborg, Denmark.
authors: Lone Deibjerg
authors: LD
authors: Kristensen
authors: Department of Cardiology, Odense University Hospital, Odense, Denmark.
authors: Hans
authors: H
authors: Mickley
authors: Department of Cardiology, Lillbaelt Hospital-Vejle, Vejle, Denmark.
authors: Henrik
authors: H
authors: Munkholm
authors: Department of Cardiology Aarhus University Hospital-Skejby, Aarhus, Denmark.
authors: Ole
authors: O
authors: Gøtzsche
authors: Department of Cardiology, Regional Hospital Herning, Herning, Denmark.
authors: Lars Lyhne
authors: LL
authors: Knudsen
authors: Department of Cardiology Aarhus University Hospital-Skejby, Aarhus, Denmark.
authors: Hans Erik
authors: HE
authors: Bøtker
authors: Department of Clinical Epidemiology, Aarhus University Hosptial, Aarhus, Denmark.
authors: Lars
authors: L
authors: Pedersen
authors: Department of Cardiology Aarhus University Hospital-Skejby, Aarhus, Denmark ; Department of Clinical Epidemiology, Aarhus University Hosptial, Aarhus, Denmark.
authors: Morten
authors: M
authors: Schmidt
keywords: coronary computed tomography angiography; database; epidemiology; registries
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