title: Orthotopic neobladder reconstruction.
abstract: Orthotopic neobladder reconstruction is becoming an increasingly common urinary diversion following cystectomy for bladder cancer. This is in recognition of the potential benefits of neobladder surgery over creation of an ileal conduit related to quality of life (QoL), such as avoiding the need to form a stoma with its cosmetic, psychological and other potential complications. The PubMed database was searched using relevant search terms for articles published electronically between January 1994 and April 2014. Full-text articles in English or with English translation were assessed for relevance to the topic before being included in the review. Patients with neobladders have comparable or better post-operative sexual function than those with ileal conduits. They also have comparable QoL to those with ileal conduits. Orthotopic neobladder is a good alternative to ileal conduit in suitable patients who do not want a stoma and are motivated to comply with neobladder training. However, the selection of a neobladder as the urinary diversion of choice requires that patients have good renal and liver functions and are likely to be compliant with neobladder training. With benefits also come potential risks of neobladder formation. These include electrolyte abnormalities and nocturnal incontinence. This short review highlights current aspects of neobladder formation and its potential advantages.
authors: Department of Urology, Fremantle Hospital and Health Service, Fremantle, Western Australia.
authors: Dwayne T S
authors: DT
authors: Chang
authors: Department of Surgery, University of Melbourne, Victoria ; Ludwig Institute for Cancer Research, Austin Hospital, Melbourne, Victoria ; Department of Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.
authors: Nathan
authors: N
authors: Lawrentschuk
keywords: Erectile dysfunction; quality of life; urinary bladder; urinary diversion; urinary incontinence
references: BJU Int. 2004 Aug;94(3):350-4
references: 15291866
references: Scand J Urol Nephrol. 2008;42(4):344-51
references: 19230167
references: Urology. 2008 May;71(5):919-23
references: 18355900
references: J Wound Ostomy Continence Nurs. 2013 Mar-Apr;40(2):171-80; quiz E1-2
references: 23466722
references: Urology. 2000 Jun;55(6):862-5
references: 10840094
references: J Wound Ostomy Continence Nurs. 2013 Jan-Feb;40(1):73-82
references: 23222970
references: J Urol. 2010 Jul;184(1):198-202
references: 20478603
references: Scand J Urol Nephrol. 2009;43(1):37-41
references: 18949634
references: Int J Urol. 2010 Sep;17(9):768-73
references: 20649826
references: J Pediatr Urol. 2012 Apr;8(2):145-52
references: 21493159
references: Urol Ann. 2013 Jul;5(3):190-6
references: 24049384
references: J Urol. 2013 May;189(5):1782-8
references: 23159582
references: J Urol. 2000 Jul;164(1):10-3
references: 10840413
references: Eur Urol. 2010 Jun;57(6):1045-51
references: 20096993
references: Arch Phys Med Rehabil. 2002 Aug;83(8):1165-70
references: 12161841
references: BJU Int. 2004 Dec;94(9):1317-21
references: 15610113
references: Swiss Med Wkly. 2001 Mar 10;131(9-10):127-32
references: 11416968
references: Int Braz J Urol. 2013 Jul-Aug;39(4):474-83
references: 24054377
references: Health Qual Life Outcomes. 2013 Mar 12;11:43
references: 23497292
references: Urology. 2001 Nov;58(5):712-6
references: 11711347
references: ISRN Urol. 2012;2012:342796
references: 22523713
references: World J Urol. 2000 Oct;18(5):330-7
references: 11131310
references: BJU Int. 2014 May;113(5):726-32
references: 24053658
references: J Urol. 2001 May;165(5):1427-32
references: 11342891
references: Eur J Surg Oncol. 2009 Aug;35(8):858-64
references: 18824319
references: BJU Int. 2004 Aug;94(3):355-9
references: 15291867
references: J Urol. 2004 Oct;172(4 Pt 1):1323-7
references: 15371833
references: J Urol. 2006 Jul;176(1):161-6
references: 16753394
references: Scand J Urol Nephrol. 2007;41(1):14-9
references: 17366097
references: Ann R Coll Surg Engl. 2009 Oct;91(7):565-9
references: 19558757
references: ScientificWorldJournal. 2004 Jun 07;4 Suppl 1:135-41
references: 15349539