title: Totaled health risks in vascular events score predicts clinical outcome and symptomatic intracranial hemorrhage in chinese patients after thrombolysis.
abstract: OBJECTIVE
  The performance of the Totaled Health Risks in Vascular Events (THRIVE) score in predicting clinical outcomes in Chinese patients with acute ischemic stroke post intravenous thrombolysis is unknown.
  
  
  METHODS
  Data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China) study was used to compare the THRIVE score with other scores used to predict clinical outcomes and symptomatic intracranial hemorrhage after intravenous thrombolysis.
  
  
  RESULTS
  Among the 1128 patients with acute ischemic stroke who were included in this study, areas under the curve of the THRIVE score for symptomatic intracranial hemorrhage, 3-month poor functional outcomes, and death rate were 0.69, 0.71, and 0.78, respectively. The increased THRIVE score was related to the higher risk of developing symptomatic intracranial hemorrhage, poor functional outcomes, or death in patients with acute ischemic stroke at 3 months after thrombolysis.
  
  
  CONCLUSIONS
  The THRIVE score predicted reliably the risks of developing symptomatic intracranial hemorrhage, poor functional outcome, or death after intravenous thrombolysis therapy in Chinese patients with acute ischemic stroke.
authors: From the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; and China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing, China.
authors: Weiqi
authors: W
authors: Chen
authors: From the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; and China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing, China.
authors: Yuesong
authors: Y
authors: Pan
authors: From the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; and China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing, China.
authors: Xingquan
authors: X
authors: Zhao
authors: From the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; and China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing, China.
authors: Xiaoling
authors: X
authors: Liao
authors: From the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; and China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing, China.
authors: Liping
authors: L
authors: Liu
authors: From the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; and China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing, China.
authors: Chunjuan
authors: C
authors: Wang
authors: From the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; and China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing, China. yongjunwang1962@gmail.com yilong528@gmail.com.
authors: Yilong
authors: Y
authors: Wang
authors: From the Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; and China National Clinical Research Center for Neurological Diseases (NCRC-ND), Beijing, China. yongjunwang1962@gmail.com yilong528@gmail.com.
authors: Yongjun
authors: Y
authors: Wang
mesh_terms: D000368:Aged; D002545:Brain Ischemia / Q000534:rehabilitation*; D002138:Calibration; D002681:China; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D007262:Infusions, Intravenous; D020300:Intracranial Hemorrhages / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012042:Registries; D015203:Reproducibility of Results; D018570:Risk Assessment; D012720:Severity of Illness Index; D000071939:Stroke Rehabilitation; D015912:Thrombolytic Therapy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents
keywords: prognosis; stroke; thrombolytic therapy