title: Pediatric acute respiratory distress syndrome: consensus recommendations from the Pediatric Acute Lung Injury Consensus Conference.
abstract: OBJECTIVE
  To describe the final recommendations of the Pediatric Acute Lung Injury Consensus Conference.
  
  
  METHODS
  Consensus conference of experts in pediatric acute lung injury.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  PICU patients with evidence of acute lung injury or acute respiratory distress syndrome.
  
  
  METHODS
  None.
  
  
  METHODS
  A panel of 27 experts met over the course of 2 years to develop a taxonomy to define pediatric acute respiratory distress syndrome and to make recommendations regarding treatment and research priorities. When published, data were lacking a modified Delphi approach emphasizing strong professional agreement was used.
  
  
  RESULTS
  A panel of 27 experts met over the course of 2 years to develop a taxonomy to define pediatric acute respiratory distress syndrome and to make recommendations regarding treatment and research priorities. When published data were lacking a modified Delphi approach emphasizing strong professional agreement was used. The Pediatric Acute Lung Injury Consensus Conference experts developed and voted on a total of 151 recommendations addressing the following topics related to pediatric acute respiratory distress syndrome: 1) Definition, prevalence, and epidemiology; 2) Pathophysiology, comorbidities, and severity; 3) Ventilatory support; 4) Pulmonary-specific ancillary treatment; 5) Nonpulmonary treatment; 6) Monitoring; 7) Noninvasive support and ventilation; 8) Extracorporeal support; and 9) Morbidity and long-term outcomes. There were 132 recommendations with strong agreement and 19 recommendations with weak agreement. Once restated, the final iteration of the recommendations had none with equipoise or disagreement.
  
  
  CONCLUSIONS
  The Consensus Conference developed pediatric-specific definitions for acute respiratory distress syndrome and recommendations regarding treatment and future research priorities. These are intended to promote optimization and consistency of care for children with pediatric acute respiratory distress syndrome and identify areas of uncertainty requiring further investigation.
mesh_terms: D000367:Age Factors; D001784:Blood Gas Analysis; D015897:Comorbidity; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods; D006801:Humans; D015278:Intensive Care Units, Pediatric; D008991:Monitoring, Physiologic / Q000379:methods; D013902:Radiography, Thoracic; D012121:Respiration, Artificial / Q000379:methods; D012127:Respiratory Distress Syndrome, Newborn / Q000150:complications / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy*; D012720:Severity of Illness Index; D013997:Time Factors
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