title: J-edited pure shift NMR for the facile measurement of (n)J(HH) for specific protons.
abstract: We report a novel 1D J-edited pure shift NMR experiment (J-PSHIFT) that was constructed from a pseudo 2D experiment for the direct measurement of proton-proton scalar couplings. The experiment gives homonuclear broad-band (1)H-decoupled (1)H NMR spectra, which provide a single peak for chemically distinct protons, and only retain the homonuclear-scalar-coupled doublet pattern at the chemical-shift positions of the protons in the coupled network of a specific proton. This permits the direct and unambiguous measurement of the magnitudes of the couplings. The incorporation of a 1D selective correlation spectroscopy (COSY)/ total correlation spectroscopy (TOCSY) block in lieu of the initial selective pulse, results in the exclusive detection of the correlated spectrum of a specific proton.
authors: NMR Research Centre and Solid State Structural Chemistry Unit, Indian Institute of Science, Bangalore 560012 (India), Fax: (+81) 8023601550.
authors: Sachin Rama
authors: SR
authors: Chaudhari
authors: N
authors: N
authors: Suryaprakash
keywords: NMR spectroscopy; analytical methods; broadband decoupling; homonuclear scalar couplings; pure shift spectra