title: Gastric neo-adenocarcinoma arising in a gastric tube after Ivor Lewis oesophagectomy for oesophageal adenocarcinoma.
abstract: A 69-year-old man, seven years post Ivor-Lewis oesophagectomy for oesophageal adenocarcinoma, was diagnosed to have a moderately differentiated 4 cm, malignant ulcer within the gastric tube remnant on an endoscopic biopsy. His original presentation was with a T1N0 oesophageal adenocarcinoma, histologically intestinal in type with inflammatory features. He presented with anaemia and melena due to a malignant ulcer in the mid body of his gastric tube on an endoscopy which was confirmed to be a gastric neo-adenocarcinoma on biopsy. He underwent right posterolateral thoracotomy and a wedge resection of the gastric tube including the tumour. Pathology confirmed a T3 N0 (0/7 lymph nodes) with clear margins moderately differentiated adenocarcinoma of intestinal phenotype with papillary features and was reported to be a histopathologically new tumour. Proposed surgical treatments in such patients are dependent on patient's fitness for major resection and may vary from Endoscopic Mucosal Resection to partial resection with preservation of right gastroepiploic vessels or total gastrectomy with intestinal interposition via a retromediastinal route. We suggest that regular endoscopic surveillance may be indicated in such post-oesophagectomy patients as the number of patients developing gastric tube cancers may increase with improve survival of those patients.
authors: Speciality Registrar, Department of Upper GI Surgery, Royal Infirmary Glasgow, UK faisal.hanif@ymail.com.
authors: Faisal
authors: F
authors: Hanif
authors: Resident Doctor, Department of Upper GI Surgery, Royal Infirmary Glasgow, UK.
authors: Joana
authors: J
authors: Kerr
authors: Consultant Pathologist, Department of Pathology, Royal Infirmary Glasgow, UK.
authors: James J
authors: JJ
authors: Going
authors: Consultant Surgeon, Specialty Department of Upper GI Surgery, Royal Infirmary Glasgow, UK.
authors: Grant
authors: G
authors: Fullarton
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000601:surgery; D000368:Aged; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000601:surgery*; D016629:Esophagectomy / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000601:surgery; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D016896:Treatment Outcome
keywords: Oesophageal surgery; endoscopy; gastric tube cancer