title: Is hormonal treatment still an option in acne today?
abstract: Hormonal treatment is indicated in cases of papulopustular, nodular and conglobate acne in females with identified hyperandrogenism, in adult women who have monthly flare-ups and when standard therapeutic options are unsuccessful or inappropriate. This review summarizes the latest information on hormonal therapies including: combined oral contraceptives; anti-androgens, such as cyproterone acetate, spironolactone and flutamide; low-dose glucocorticoids and gonadotropin-releasing hormone agonists. It also shares the authors' recommendations for treatment based on the studies discussed here, and personal experience.
authors: Department of Medical Sciences, Section of Dermatology, University of Ferrara, Azienda Ospedaliero-Universitaria di Ferrara, via Aldo Moro, 8, 44124, Cona, Ferrara, Italy.
authors: V
authors: V
authors: Bettoli
authors: Department of Medical Sciences, Section of Dermatology, University of Ferrara, Azienda Ospedaliero-Universitaria di Ferrara, via Aldo Moro, 8, 44124, Cona, Ferrara, Italy.
authors: S
authors: S
authors: Zauli
authors: Department of Medical Sciences, Section of Dermatology, University of Ferrara, Azienda Ospedaliero-Universitaria di Ferrara, via Aldo Moro, 8, 44124, Cona, Ferrara, Italy.
authors: A
authors: A
authors: Virgili
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy* / Q000209:etiology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000726:Androgen Antagonists / Q000627:therapeutic use; D003278:Contraceptives, Oral, Hormonal / Q000627:therapeutic use*; D017373:Cyproterone Acetate / Q000627:therapeutic use; D005260:Female; D005485:Flutamide / Q000627:therapeutic use; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists; D006728:Hormones / Q000627:therapeutic use*; D006801:Humans; D017588:Hyperandrogenism / Q000150:complications; D013148:Spironolactone / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000726:Androgen Antagonists; D003278:Contraceptives, Oral, Hormonal; D006728:Hormones; D013148:Spironolactone; D007987:Gonadotropin-Releasing Hormone; D017373:Cyproterone Acetate; D005485:Flutamide