title: Temporal trends in results of 9170 myocardial perfusion imaging studies (2004 to 2013).
abstract: BACKGROUND
  To assess the frequency of normal and abnormal myocardial perfusion imaging (MPI) in a consecutive cohort of patients from Pakistan over a period of 8.5 years.
  
  
  METHODS
  We assessed 9170 patients who had undergone stress-rest MPI between January 2004 and June 2013. Patients were assessed for change in demographics, risk factors, and frequency of abnormal and normal MPI.
  
  
  RESULTS
  Overall mean age and male predominance of studied cohort was ≈ 55 years and ≈ 55:45 (M:F), respectively, with no appreciable decline or rise. Marked decline in exercise as mode of stress (from 71% to 35%, p value significant) was noted during the study period. Regarding the risk factors for CAD, only hypertension was noted to have a significant rising trend during the study period. Trend of MPI results over study period was found non-significant from 2004 till 2006 but from 2007 onward (except 2008), a marginal but significant decline in abnormal MPIs (from 45% to 42%; significant p value) and rise in normal MPI (from 55% to 58%; significant p value) was noted.
  
  
  CONCLUSIONS
  We conclude that over the past 8.5 years, a marginal but significant decline in abnormal and a rise in normal MPIs trend have been observed. An exorbitant rise in use of vasodilator as a method of stress was also observed. We envisaged a follow-up study to ascertain lower negative predictive value of vasodilator as a possible reason and till than results of this and other such studies must be read cautiously.
authors: 1. Head Nuclear Medicine Section, Dept of Radiology, Aga Khan University Hospital (AKUH), Karachi, Pakistan. 2. Department of Nuclear Radiology, Karachi Institute of Heart Diseases (KIHD), Karachi, Pakistan.. maseeh.uzzaman@aku.edu.
authors: Maseeh uz
authors: Mu
authors: Zaman
authors: Nosheen
authors: N
authors: Fatima
authors: Unaiza
authors: U
authors: Zaman
authors: Areeba
authors: A
authors: Zaman
authors: S Zahed
authors: SZ
authors: Rasheed
authors: Dad J
authors: DJ
authors: Baloch
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging / Q000639:trends*; D012984:Software; D013223:Statistics as Topic; D013997:Time Factors