title: [Use of tissue engineering in the reconstruction of flexor tendon injuries of the hand].
abstract: In his literary analysis, the author describes a novel method applied in the reconstruction of flexor tendon injuries of the hand. This procedure is named tissue engineering, and it is examined mainly under experimental circumstances. After definition of the method and descriptions of literary preliminaries the author discusses the healing process of the normal tendon tissue, then development of the scaffold, an important step of tissue engineering is described. After these topics the introduction of the pluripotent mesenchymal stem cells into the scaffold, and proliferation of these cells and development of the sliding systems are presented. The mechanical resisting ability of the formed tendon tissue is also discussed. Finally, the author concludes that as long as results of experimental research cannot be successfully applied into clinical practice, well-tried tendon reconstruction operations and high quality postoperative rehabilitation are needed.
authors: Pécs Hajnóczy u. 25/A, II. em. 2. 7633.
authors: Vilmos
authors: V
authors: Bíró
mesh_terms: D049109:Cell Proliferation; D006230:Hand Injuries / Q000601:surgery*; D006801:Humans; D059630:Mesenchymal Stem Cells; D019637:Orthopedic Procedures / Q000379:methods*; D019651:Plastic Surgery Procedures / Q000379:methods*; D013499:Surface Properties; D013708:Tendon Injuries / Q000601:surgery*; D013710:Tendons / Q000601:surgery*; D023822:Tissue Engineering; D054457:Tissue Scaffolds; D014945:Wound Healing
keywords: hajlítóín-sérülések; hand surgery; injuries of the flexor tendons; kézsebészet; mesenchymal stem cells; mesenchymalis őssejtek; production of new flexor tendons; szövetépítés; tissue engineering; új hajlítóín létrehozása