title: Preventing group B streptococcal infections in newborns.
abstract: Despite advances in intrapartum antibiotic prophylaxis (IAP), group B streptococcal infection continues to be a predominant cause of early-onset disease in neonates. About 2% of neonates exposed to group B Streptococcus develop clinical manifestations including sepsis, pneumonia, and meningitis. Screening in late pregnancy reduces the incidence of early-onset sepsis by more than 80%. Clinicians must be able to identify the risk factors and clinical manifestations of group B streptococcal infection and to understand management and prevention guidelines.
authors: Kelly Porta is an assistant professor and academic coordinator in the PA program at Hofstra University in New York. She practices at the newborn nursery at Montefiore Medical Center and pediatric ICU at Jacobi Medical Center. Denise Rizzolo is an associate professor in the PA program at Seton Hall University in South Orange, N.J., an assistant clinical professor in the Pace completion program in New York City, and practices urgent care in Springfield, N.J. The authors have disclosed no potential conflicts of interest, financial or otherwise.
authors: Kelly
authors: K
authors: Porta
authors: Denise
authors: D
authors: Rizzolo
mesh_terms: D019072:Antibiotic Prophylaxis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000382:microbiology / Q000517:prevention & control*; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000382:microbiology / Q000517:prevention & control*; D011296:Prenatal Diagnosis; D012307:Risk Factors; D013290:Streptococcal Infections / Q000382:microbiology / Q000517:prevention & control* / Q000635:transmission; D013292:Streptococcus agalactiae