title: New sugar-derived bifunctional chiral ureas as highly effective organocatalysts in asymmetric aza-Henry reaction.
abstract: A simple synthesis of series of new catalysts derived from chiral bifunctional ureas is described. The aza-Henry reaction of imines with nitromethane was promoted by sugar derived bifunctional organocatalysts to give optically active β-nitroamines. The aza-Henry reaction products were obtained in good yields (35-98%) and ee up to 99%.
authors: Department of Organic and Applied Chemistry, University of Łódź, Tamka 12, 91-403 Łódź, Poland.
authors: Jolanta
authors: J
authors: Robak
authors: Department of Organic and Applied Chemistry, University of Łódź, Tamka 12, 91-403 Łódź, Poland.
authors: Bogusław
authors: B
authors: Kryczka
authors: Department of Organic and Applied Chemistry, University of Łódź, Tamka 12, 91-403 Łódź, Poland.
authors: Barbara
authors: B
authors: Świerczyńska
authors: Department of Organic and Applied Chemistry, University of Łódź, Tamka 12, 91-403 Łódź, Poland.
authors: Anna
authors: A
authors: Zawisza
authors: Department of Organic and Applied Chemistry, University of Łódź, Tamka 12, 91-403 Łódź, Poland. Electronic address: porwany@chemia.uni.lodz.pl.
authors: Stanisław
authors: S
authors: Porwański
mesh_terms: D001372:Aza Compounds / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D013237:Stereoisomerism; D014508:Urea / Q000737:chemistry*
chemical_list: D001372:Aza Compounds; D002241:Carbohydrates; D014508:Urea
keywords: Aza-Henry; Organocatalyst; Saccharides; Urea