title: Multiple lithium-dependent Brugada syndrome unmasking events in a bipolar patient.
abstract: This case demonstrates two important points about Brugada syndrome unmasking: electrocardiograph abnormality severity may correspond to lithium levels and unmasking may occur in the therapeutic range of lithium. Also, the correlation of CACNA1C with Brugada and Bipolar suggests allelic disequilibrium, leading to a subpopulation of bipolar patients sensitive to arrhythmia.
authors: Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center New Orleans, Louisiana.
authors: Rebecca R
authors: RR
authors: Crawford
authors: Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center New Orleans, Louisiana.
authors: Ashlee N
authors: AN
authors: Higdon
authors: Department of Internal Medicine, Louisiana State University Medical Center Lafayette, Louisiana.
authors: David B
authors: DB
authors: Casey
authors: Division of Cardiology, Louisiana State University Medical Center Lafayette, Louisiana.
authors: David E
authors: DE
authors: Good
authors: Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center New Orleans, Louisiana.
authors: Imran N
authors: IN
authors: Mungrue
keywords: Bipolar disorder; Brugada syndrome; ECG/EKG; lithium; single-nucleotide polymorphism