title: Correlation of fractal dimension with histomorphometry in maxillary sinus lifting using autogenous bone graft.
abstract: The aim of this study was to determine the pattern of bone remodeling after maxillary sinus lifting in humans by means of fractal dimension (FD) and histomorphometric analysis. Therefore, the correlation between FD and the histomorphometric findings was evaluated. Sixteen patients with posterior edentulous maxilla were enrolled in this study. Maxillary sinus lifting was performed using autogenous bone grafted from the mandibular retromolar area. Three direct digital panoramic radiographs were obtained: before surgery (Group 1), immediately postoperatively (Group 2) and after 6 months of healing (Group 3) for FD analysis. Biopsies were taken after 6 months, processed and submitted to histological and histomorphometric analysis. Data were analyzed by Shapiro-Wilk test and ANOVA test followed by a Tukey test (a = 0.05). The bone volume fraction of newly trabecular bone (TB) and medullary area (MA) was measured as 62.75% ± 17.16% and 37.25 ± 17.16%, respectively. Significant difference in FD analysis was measured between Group 1 and Group 3. No significant difference was found in the correlation between FD and histomorphometric analysis for TB and MA (p = 0.84). In conclusion, all performed analyses were effective in assessing the bone-remodeling pattern in the maxillary sinus, offering complementary information about healing and predictable outcomes. There were no correlations between FD and histomorphometric analysis.
authors: Department of Diagnosis and Surgery, Araraquara Dental School, UNESP - Univ Estadual Paulista, Araraquara, SP, Brazil.
authors: Rafael Scaf
authors: RS
authors: de Molon
authors: Department of Diagnosis and Surgery, Araraquara Dental School, UNESP - Univ Estadual Paulista, Araraquara, SP, Brazil.
authors: Wagner Nunes
authors: WN
authors: de Paula
authors: Oral Radiology, Department of Dentistry, Aarhus University, Aarhus, Denmark.
authors: Rubens
authors: R
authors: Spin-Neto
authors: Department of Diagnosis and Surgery, Araraquara Dental School, UNESP - Univ Estadual Paulista, Araraquara, SP, Brazil.
authors: Mario Henrique Arruda
authors: MH
authors: Verzola
authors: Department of Diagnosis and Surgery, Araraquara Dental School, UNESP - Univ Estadual Paulista, Araraquara, SP, Brazil.
authors: Guilherme Monteiro
authors: GM
authors: Tosoni
authors: Oral Radiology, Department of Dentistry, Aarhus University, Aarhus, Denmark.
authors: Raphael Carlos Comelli
authors: RC
authors: Lia
authors: Department of Diagnosis and Surgery, Araraquara Dental School, UNESP - Univ Estadual Paulista, Araraquara, SP, Brazil.
authors: Gulnara
authors: G
authors: Scaf
authors: Department of Diagnosis and Surgery, Araraquara Dental School, UNESP - Univ Estadual Paulista, Araraquara, SP, Brazil.
authors: Elcio
authors: E
authors: Marcantonio
mesh_terms: D001706:Biopsy; D016723:Bone Remodeling; D016025:Bone Transplantation / Q000379:methods*; D003758:Dental Implantation, Endosseous; D005260:Female; D017709:Fractals; D006801:Humans; D007576:Jaw, Edentulous, Partially / Q000473:pathology / Q000601:surgery; D008297:Male; D008334:Mandible / Q000637:transplantation*; D008437:Maxilla / Q000473:pathology / Q000601:surgery*; D008443:Maxillary Sinus / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D011862:Radiography, Panoramic; D059546:Sinus Floor Augmentation / Q000379:methods*; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014945:Wound Healing