title: Fusobacterium necrophorum tonsillitis: an important cause of tonsillitis in adolescents and young adults.
abstract: The role of Fusobacterium necrophorum in tonsillitis in adolescents and young adults was retrospectively investigated by culture examination. We compared the prevalence of F. necrophorum in 212 subjects with confirmed clinical tonsillitis and in 176 subjects with confirmed no clinical tonsillitis. The prevalence of F. necrophorum was significantly higher (p < 0.001) in subjects with clinical tonsillitis (27%) compared to subjects with no clinical tonsillitis (6%). These results clearly demonstrate the role of F. necrophorum in tonsillitis. By diagnosing and treating F. necrophorum tonsillitis with, for example, penicillin, metronidazole, or both, we might prevent some cases of Lemierre syndrome.
authors: Department of Biomedicine, Aarhus University, Aarhus, Denmark. Electronic address: anders.jensen@biomed.au.dk.
authors: A
authors: A
authors: Jensen
authors: Department of Clinical Microbiology, Viborg, Denmark.
authors: T M
authors: TM
authors: Hansen
authors: Medical Department, Viborg Regional Hospital, Viborg, Denmark.
authors: S
authors: S
authors: Bank
authors: Medical Department, Viborg Regional Hospital, Viborg, Denmark.
authors: L H
authors: LH
authors: Kristensen
authors: Department of Clinical Microbiology, Viborg, Denmark.
authors: J
authors: J
authors: Prag
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002648:Child; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005674:Fusobacterium Infections / Q000453:epidemiology* / Q000382:microbiology*; D005675:Fusobacterium necrophorum / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D014069:Tonsillitis / Q000453:epidemiology* / Q000382:microbiology*; D055815:Young Adult
keywords: Centor Criteria; Fusobacterium necrophorum; Lemierre syndrome; tonsillitis; β-Haemolytic streptococci