title: Complete remission of primary hepatic lymphoma in a patient with human immunodeficiency virus.
abstract: Diffuse large B cell primary hepatic lymphoma is a rare disease with limited available information regarding treatment strategy. Although the liver contains lymphoid tissue and is an important site for lymphocytes activation, primary hepatic lymphoma is rare. Host factors make the liver a poor environment for malignant lymphoma development. Its coexistence with human immunodeficiency virus (HIV) infection increases morbidity and mortality risks. Additionally, jaundice increases chances of developing adverse effects from chemotherapy. Here, we report a case of diffuse large B cell primary hepatic lymphoma in a 32-year-old HIV positive man. Due to elevated liver enzyme levels and jaundice, the patient was initially treated with an R-DHAP regimen, which was replaced with an R-CHOP regimen. Restaging images with a positron emission tomography scan after the latest chemotherapy cycle confirmed remission. This is the first report of complete remission of primary hepatic diffuse large B cell lymphoma in an HIV positive patient in the English literature.
authors: David Widjaja, Mohammad AlShelleh, Myrta Daniel, Yevgeniy Skaradinskiy, Division of Gastroenterology and Division of Oncology and Hematology, Department of Medicine, Bronx Lebanon Hospital Center, Bronx, NY 10457, United States.
authors: David
authors: D
authors: Widjaja
authors: David Widjaja, Mohammad AlShelleh, Myrta Daniel, Yevgeniy Skaradinskiy, Division of Gastroenterology and Division of Oncology and Hematology, Department of Medicine, Bronx Lebanon Hospital Center, Bronx, NY 10457, United States.
authors: Mohammad
authors: M
authors: AlShelleh
authors: David Widjaja, Mohammad AlShelleh, Myrta Daniel, Yevgeniy Skaradinskiy, Division of Gastroenterology and Division of Oncology and Hematology, Department of Medicine, Bronx Lebanon Hospital Center, Bronx, NY 10457, United States.
authors: Myrta
authors: M
authors: Daniel
authors: David Widjaja, Mohammad AlShelleh, Myrta Daniel, Yevgeniy Skaradinskiy, Division of Gastroenterology and Division of Oncology and Hematology, Department of Medicine, Bronx Lebanon Hospital Center, Bronx, NY 10457, United States.
authors: Yevgeniy
authors: Y
authors: Skaradinskiy
keywords: Diffuse B cell lymphoma; Human immunodeficiency virus; Primary hepatic lymphoma; R-CHOP; R-DHAP