title: Treatment of patients with refractory atopic dermatitis sensitized to house dust mites by using sublingual allergen immunotherapy.
abstract: Even though atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases, its treatment remains a challenge in clinical practice, with most approaches limited to symptomatic, unspecific anti-inflammatory, or immunosuppressive treatments. Many studies have shown AD to have multiple causes that activate complex immunological and inflammatory pathways. However, aeroallergens, and especially the house dust mite (HDM), play a relevant role in the elicitation or exacerbation of eczematous lesions in many AD patients. Accordingly, allergen-specific immunotherapy has been used in AD patients with the aim of redirecting inappropriate immune responses. Here, we report three cases of refractory AD sensitized to HDM who were treated with sublingual immunotherapy.
authors: Department of Dermatology, Gil Medical Center, Graduate School of Medicine, Gachon University, Incheon, Korea.
authors: Joon-Seok
authors: JS
authors: Choi
authors: Department of Dermatology, Gil Medical Center, Graduate School of Medicine, Gachon University, Incheon, Korea.
authors: Ha-Ryeong
authors: HR
authors: Ryu
authors: Department of Dermatology, Gil Medical Center, Graduate School of Medicine, Gachon University, Incheon, Korea.
authors: Cheol-Hyun
authors: CH
authors: Yoon
authors: Department of Dermatology, Gil Medical Center, Graduate School of Medicine, Gachon University, Incheon, Korea.
authors: Ji-Hoon
authors: JH
authors: Kim
authors: Department of Dermatology, Gil Medical Center, Graduate School of Medicine, Gachon University, Incheon, Korea.
authors: Jin-Ok
authors: JO
authors: Baek
authors: Department of Dermatology, Gil Medical Center, Graduate School of Medicine, Gachon University, Incheon, Korea.
authors: Joo-Young
authors: JY
authors: Roh
authors: Department of Dermatology, Gil Medical Center, Graduate School of Medicine, Gachon University, Incheon, Korea.
authors: Jong-Rok
authors: JR
authors: Lee
keywords: Atopic dermatitis; Pyroglyphidae; Sublingual immunotherapy