title: The effect of surgical treatment of phaeochromocytoma on concomitant arterial hypertension and diabetes mellitus in a single-centre retrospective study.
abstract: BACKGROUND
  Phaeochromocytoma is one of the numerous causes of secondary hypertension. Furthermore, phaeochromocytoma may first present with type 2 diabetes mellitus. The objective of our study was to evaluate the effects of adrenalectomy on patient recovery with regards to normotension and well-controlled glycaemia.
  
  
  METHODS
  The retrospective analysis involved 67 patients with phaeochromocytoma operated between 2006 and mid-2012. The pre-operative diagnoses were made in the departments of internal medicine and endocrinology. Based on laboratory tests and diagnostic imaging, we were able to confirm the diagnosis of phaeochromocytoma in 42 (62.7%) patients. We verified the influence of adrenalectomy on the level of patient recovery, with regards to normotension and glycaemic control: arterial pressure and fasting glycaemia levels were obtained on the day of hospital discharge, at follow-up 3 months post-operatively and 1 year after surgical intervention.
  
  
  RESULTS
  Of the 67 patients operated for phaeochromocytoma, 48 (71.6%) were treated laparoscopically, whereas 19 (28.4%) underwent open adrenalectomy. Arterial hypertension was recorded in 53 (79.1%) cases. Furthermore, among this group, diabetes mellitus coexisted in 21 (31.3%) cases. Postoperatively, 70% of cases of arterial hypertension and 90% of type 2 diabetes mellitus were cured. Additionally, a high rate of patients reported a quantitative reduced use of antihypertensive medicines.
  
  
  CONCLUSIONS
  In the majority of patients, surgical treatment of symptomatic phaeochromocytoma leads to a regression of arterial hypertension, or a reduction of the number or doses of medicines taken in one's treatment, and glucose-intolerance symptoms.
authors: Department of General and Thoracic Surgery, Medical University of Warsaw, Poland.
authors: Ryszard
authors: R
authors: Pogorzelski
authors: Department of General and Thoracic Surgery, Medical University of Warsaw, Poland.
authors: Sadegh
authors: S
authors: Toutounchi
authors: Department of General and Thoracic Surgery, Medical University of Warsaw, Poland.
authors: Ewa
authors: E
authors: Krajewska
authors: Department of General and Thoracic Surgery, Medical University of Warsaw, Poland.
authors: Patryk
authors: P
authors: Fiszer
authors: Department of General and Thoracic Surgery, Medical University of Warsaw, Poland.
authors: Marcin
authors: M
authors: Łykowski
authors: Department of Urology, Multidisciplinary Hospital Warsaw-Międzylesie, Poland.
authors: Łukasz
authors: Ł
authors: Zapała
authors: Department of General and Thoracic Surgery, Medical University of Warsaw, Poland.
authors: Małgorzata
authors: M
authors: Szostek
authors: Department of General and Thoracic Surgery, Medical University of Warsaw, Poland.
authors: Wawrzyniec
authors: W
authors: Jakuczun
authors: Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Poland.
authors: Janusz
authors: J
authors: Pachucki
authors: Department of General and Thoracic Surgery, Medical University of Warsaw, Poland.
authors: Maciej
authors: M
authors: Skórski
keywords: diabetes; hypertension; phaeochromocytoma