title: Rate at 120/min provides qualified chest compression during cardiopulmonary resuscitation.
abstract: OBJECTIVE
  The quality of cardiopulmonary resuscitation (CPR) is a very important prognostic factor for cardiac arrest. Chest compression is thought to be one of the most important aspects of high-quality CPR. Recent studies have prompted that there may be an interaction between chest compression rate and other factors related to the quality of chest compression. We aimed to investigate the effect of different compression rates on chest compression depth, recoil, and rescuers' fatigue point during CPR.
  
  
  METHODS
  Participants performed 2 minutes of chest compression-only CPR after the guiding sounds, at 3 rates (100, 120, and 140 compressions/min) in random sequence. A repeated-measures analysis of variance was used to compare the average chest compression depth and other factors related to the quality of chest compression among the groups.
  
  
  RESULTS
  As the chest compression rate increases through all the 3 rates, the fractions of chest compressions with complete release and the fractions of chest compressions with sufficient depth were deteriorated at the rate of 140 compressions/min (P < .05), although the average compression depth was above the recommended 2010 guideline depth of 5 cm(P > .05). Of note, the fatigue point at 140 compressions/min happened significantly (P < .05) sooner.
  
  
  CONCLUSIONS
  Our study supported the concern of some that there may be a risk of increasing recommended chest compression rate without providing an upper limit. An appropriate choice may be 120 compressions/min.
authors: Department of Emergency Medicine, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China.
authors: Yaru
authors: Y
authors: Zou
authors: Department of Emergency Medicine, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China.
authors: Wen
authors: W
authors: Shi
authors: Department of Emergency Medicine, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China.
authors: Ying
authors: Y
authors: Zhu
authors: Department of Emergency Medicine, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China.
authors: Ranjun
authors: R
authors: Tao
authors: Ruijin Clinical Medical College, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China.
authors: Ying
authors: Y
authors: Jiang
authors: Department of Emergency Medicine, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China.
authors: Shanfeng
authors: S
authors: Li
authors: Department of Emergency Medicine, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China.
authors: Jing
authors: J
authors: Ye
authors: Department of Emergency Medicine, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China.
authors: Yiming
authors: Y
authors: Lu
authors: Department of Emergency Medicine, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China. Electronic address: croissantjj@126.com.
authors: Jie
authors: J
authors: Jiang
authors: Department of Emergency Medicine, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, Shanghai, China. Electronic address: tongjj_h@163.com.
authors: Jianjing
authors: J
authors: Tong
mesh_terms: D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D018592:Cross-Over Studies; D006801:Humans; D008348:Manikins; D017410:Practice Guidelines as Topic; D011312:Pressure; D011446:Prospective Studies