title: Au(I)-catalyzed annulation of propargyl amine with aldehydes: one-pot cascade synthesis of 2,5-dimethylpyrazines.
abstract: 3-Substituted 2,5-dimethylpyrazines were synthesized in high yields via a one-pot cascade annulation of easily available propargyl amine with aldehydes catalyzed by Au(PPh2Cy)Cl.
authors: Department of Chemistry, Tsinghua University, Beijing 100084, China. andrew-su@163.com.|National Engineering Laboratory for Rice and Byproduct Deep Processing, Central South University of Forestry and Technology, Changsha 410004, China. andrew-su@163.com.
authors: Ji
authors: J
authors: Su
authors: Department of Chemistry, Tsinghua University, Beijing 100084, China. liuhuixin9015@163.com.
authors: Huixin
authors: H
authors: Liu
authors: Department of Chemistry, Tsinghua University, Beijing 100084, China. ruimao@mail.tsinghua.edu.cn.
authors: Ruimao
authors: R
authors: Hua
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure; D050607:Organogold Compounds / Q000737:chemistry*; D010293:Pargyline / Q000031:analogs & derivatives* / Q000737:chemistry; D011437:Propylamines / Q000737:chemistry*; D011719:Pyrazines / Q000138:chemical synthesis*
chemical_list: D000447:Aldehydes; D050607:Organogold Compounds; D011437:Propylamines; D011719:Pyrazines; C009054:propargylamine; D010293:Pargyline; C075524:2,5-dimethylpyrazine