title: Osteolytic calvarial lesions as initial presentation of latent neurosyphilis.
abstract: We report a patient with human immunodeficiency virus infection whose initial presentation of neurosyphilis was painful calvarial lesions. A literature search reveals seven previous cases of calvarial involvement in early acquired syphilis but none in patients diagnosed with neurosyphilis. This patient emphasizes the need to consider atypical infections when encountering skull lesions, especially in the setting of human immunodeficiency virus co-infection.
authors: Department of Neurosurgery, University of Texas Health Science Center, 7702 Floyd Curl, MC 7843, San Antonio, TX 78229, USA. Electronic address: sonc2@uthscsa.edu.
authors: Colin
authors: C
authors: Son
authors: Department of Neurosurgery, University of Texas Health Science Center, 7702 Floyd Curl, MC 7843, San Antonio, TX 78229, USA.
authors: Derek
authors: D
authors: Samples
authors: Division of Hematology/Oncology, Department of Medicine, University of Texas Health Science Center, San Antonio, TX, USA.
authors: Andrew
authors: A
authors: Brenner
authors: Department of Neurosurgery, University of Texas Health Science Center, 7702 Floyd Curl, MC 7843, San Antonio, TX 78229, USA.
authors: John
authors: J
authors: Floyd
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis; D006801:Humans; D008297:Male; D009494:Neurosyphilis / Q000150:complications / Q000175:diagnosis*; D010014:Osteolysis / Q000175:diagnosis* / Q000209:etiology; D012886:Skull / Q000473:pathology*
keywords: Human immunodeficiency virus; Skull tumor; Syphilis; Syphilitic osteitis