title: Clinical outcomes for Conduits and Scaffolds in peripheral nerve repair.
abstract: The gold standard of peripheral nerve repair is nerve autograft when tensionless repair is not possible. Use of nerve autograft has several shortcomings, however. These include limited availability of donor tissue, sacrifice of a functional nerve, and possible neuroma formation. In order to address these deficiencies, researchers have developed a variety of biomaterials available for repair of peripheral nerve gaps. We review the clinical studies published in the English literature detailing outcomes and reconstructive options. Regardless of the material used or the type of nerve repaired, outcomes are generally similar to nerve autograft in gaps less than 3 cm. New biomaterials currently under preclinical evaluation may provide improvements in outcomes.
authors: David J Gerth, Jun Tashiro, Seth R Thaller, Division of Plastic, Aesthetic, and Reconstructive Surgery, DeWitt-Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, United States.
authors: David J
authors: DJ
authors: Gerth
authors: David J Gerth, Jun Tashiro, Seth R Thaller, Division of Plastic, Aesthetic, and Reconstructive Surgery, DeWitt-Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, United States.
authors: Jun
authors: J
authors: Tashiro
authors: David J Gerth, Jun Tashiro, Seth R Thaller, Division of Plastic, Aesthetic, and Reconstructive Surgery, DeWitt-Daughtry Family Department of Surgery, Leonard M. Miller School of Medicine, University of Miami, Miami, FL 33136, United States.
authors: Seth R
authors: SR
authors: Thaller
keywords: Conduit; Nerve tissue; Plastic surgery; Reconstructive surgical procedures; Scaffold