title: Cervical condition and fetal cerebral Doppler as determinants of adverse perinatal outcome after labor induction for late-onset small-for-gestational-age fetuses.
abstract: OBJECTIVE
  To estimate the combined value of fetal cerebral Doppler examination and Bishop score for predicting perinatal outcome after labor induction for small-for-gestational-age (SGA) fetuses in the presence of normal umbilical artery Doppler recordings.
  
  
  METHODS
  We conducted a cohort study in two tertiary centers, including 164 women with normal umbilical artery Doppler recordings who underwent induction of labor because of an estimated fetal weight < 10(th) percentile. The fetal middle cerebral artery pulsatility index and cerebroplacental ratio (CPR) were obtained in all cases within 24 h before induction. Cervical condition was assessed at admission using the Bishop score. A predictive model for perinatal outcomes was constructed using a decision-tree analysis algorithm.
  
  
  RESULTS
  Both a very unfavorable cervix, defined as a Bishop score < 2, (odds ratio (OR), 3.18; 95% CI, 1.28-7.86) and an abnormal CPR (OR, 2.54; 95% CI, 1.18-5.61) were associated with an increased likelihood of emergency Cesarean section for fetal distress, but only the latter was significantly associated with the need for neonatal admission (OR, 2.43; 95% CI, 1.28-4.59). In the decision-tree analysis, both criteria significantly predicted the likelihood of Cesarean section for fetal distress.
  
  
  CONCLUSIONS
  Combined use of the Bishop score and CPR improves the ability to predict overall Cesarean section (for any indication), emergency Cesarean section for fetal distress, and neonatal admission after labor induction for late-onset SGA in the presence of normal umbilical artery Doppler recordings.
authors: Obstetrics Department, Hospital Clinico Lozano Blesa, University of Zaragoza and Instituto de Investigación Sanitaria de Aragón (IISA), Zaragoza, Spain.
authors: R
authors: R
authors: Garcia-Simon
authors: Department of Maternal-Fetal Medicine, Institute Clínic of Gynecology, Obstetrics and Neonatology (ICGON), Hospital Clinic-IDIBAPS, University of Barcelona and Centre for Biomedical Research on Rare Diseases (CIBER-ER), Barcelona, Spain.
authors: F
authors: F
authors: Figueras
authors: Department of Maternal-Fetal Medicine, Institute Clínic of Gynecology, Obstetrics and Neonatology (ICGON), Hospital Clinic-IDIBAPS, University of Barcelona and Centre for Biomedical Research on Rare Diseases (CIBER-ER), Barcelona, Spain.
authors: S
authors: S
authors: Savchev
authors: Obstetrics Department, Hospital Clinico Lozano Blesa, University of Zaragoza and Instituto de Investigación Sanitaria de Aragón (IISA), Zaragoza, Spain.
authors: E
authors: E
authors: Fabre
authors: Department of Maternal-Fetal Medicine, Institute Clínic of Gynecology, Obstetrics and Neonatology (ICGON), Hospital Clinic-IDIBAPS, University of Barcelona and Centre for Biomedical Research on Rare Diseases (CIBER-ER), Barcelona, Spain.
authors: E
authors: E
authors: Gratacos
authors: Obstetrics Department, Hospital Clinico Lozano Blesa, University of Zaragoza and Instituto de Investigación Sanitaria de Aragón (IISA), Zaragoza, Spain.
authors: D
authors: D
authors: Oros
mesh_terms: D000328:Adult; D002536:Cerebral Arteries / Q000000981:diagnostic imaging / Q000196:embryology*; D002584:Cervix Uteri / Q000473:pathology*; D002585:Cesarean Section / Q000706:statistics & numerical data; D005260:Female; D005316:Fetal Distress / Q000209:etiology / Q000601:surgery; D020567:Fetal Weight; D005333:Fetus / Q000098:blood supply; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data; D007751:Labor, Induced / Q000009:adverse effects*; D016017:Odds Ratio; D010920:Placenta / Q000098:blood supply / Q000000981:diagnostic imaging; D011247:Pregnancy; D011256:Pregnancy Outcome; D018608:Ultrasonography, Doppler / Q000379:methods; D016216:Ultrasonography, Prenatal / Q000379:methods; D014469:Umbilical Arteries / Q000000981:diagnostic imaging; D002577:Uterine Cervical Diseases / Q000150:complications / Q000473:pathology
keywords: Bishop score; cerebroplacental ratio; decision tree; labor induction; late-onset intrauterine growth restriction