title: Allelic variation at 5-HTTLPR is associated with brain morphology in a Chinese population.
abstract: Previous studies have reported significant associations of 5-HTTLPR with brain structures mainly in Europeans, but the situations in other ethnic groups remain largely unknown. Here we examined the association of 5-HTTLPR with regional gray matter volume in Han Chinese, and observed significant association in the postcentral gyrus and precuneus cortex.
authors: State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China; Kunming College of Life Science, University of Chinese Academy of Sciences, Beijing, China.
authors: Jiewei
authors: J
authors: Liu
authors: Imaging Center, The First Affiliated Hospital of Kunming Medical College, Kunming, Yunnan, China.
authors: Yin
authors: Y
authors: Mo
authors: Centre for Computational Systems Biology, School of Mathematical Sciences, Fudan University, Shanghai, China; Department of Computer Science, University of Warwick, Coventry, UK.
authors: Tian
authors: T
authors: Ge
authors: State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
authors: Yi
authors: Y
authors: Wang
authors: Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China.
authors: Xiong-jian
authors: XJ
authors: Luo
authors: Centre for Computational Systems Biology, School of Mathematical Sciences, Fudan University, Shanghai, China; Department of Computer Science, University of Warwick, Coventry, UK.
authors: Jianfeng
authors: J
authors: Feng
authors: Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, MD, USA. Electronic address: limingkiz@gmail.com.
authors: Ming
authors: M
authors: Li
authors: State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China. Electronic address: sub@mail.kiz.ac.cn.
authors: Bing
authors: B
authors: Su
mesh_terms: D000328:Adult; D000483:Alleles; D000679:Amygdala / Q000378:metabolism / Q000502:physiology*; D044466:Asian People / Q000208:ethnology* / Q000235:genetics*; D001921:Brain / Q000033:anatomy & histology* / Q000378:metabolism; D016022:Case-Control Studies; D005260:Female; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D005838:Genotype; D066128:Gray Matter / Q000033:anatomy & histology / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D044382:Population Groups / Q000235:genetics; D050486:Serotonin Plasma Membrane Transport Proteins / Q000235:genetics* / Q000378:metabolism
chemical_list: C493230:SLC6A4 protein, human; D050486:Serotonin Plasma Membrane Transport Proteins
keywords: 5-HTTLPR; Han Chinese; VBM