title: Rapidly aggravated skeletal muscle metastases from an intrahepatic cholangiocarcinoma.
abstract: We present a rare case of intrahepatic cholangiocarcinoma (ICC) with multiple skeletal muscle metastases. The patient was a 55-year-old Asian woman presenting with abdominal pain; abdominal and pelvic computed tomography and magnetic resonance cholangiopancreatography revealed an unresectable ICC with hepatic metastasis and metastastatic lymphadenopathy in the porto-caval area. After 3 mo of treatment with palliative radiotherapy and chemotherapy, magnetic resonance imaging of the thoracolumbar spine detected right psoas muscle and paraspinous muscle metastases. We performed an ultrasound-guided percutaneous fine-needle biopsy that confirmed a similar pattern of poorly differentiated adenocarcinoma. The patient treated with palliative chemotherapy and achieved 10 mo of survival. Here we report the first case quickly spread to multiple sites of muscle even though the three-month treatment, compare to the other cases reported muscle metastases at diagnosis.
authors: Jiyoung Lee, Sung Wook Lee, Sang Young Han, Yang Hyun Baek, Su Young Kim, Hyo In Rhyou, Department of internal medicine, Dong-A University, College of Medicine, Busan 602-715, South Korea.
authors: Jiyoung
authors: J
authors: Lee
authors: Jiyoung Lee, Sung Wook Lee, Sang Young Han, Yang Hyun Baek, Su Young Kim, Hyo In Rhyou, Department of internal medicine, Dong-A University, College of Medicine, Busan 602-715, South Korea.
authors: Sung Wook
authors: SW
authors: Lee
authors: Jiyoung Lee, Sung Wook Lee, Sang Young Han, Yang Hyun Baek, Su Young Kim, Hyo In Rhyou, Department of internal medicine, Dong-A University, College of Medicine, Busan 602-715, South Korea.
authors: Sang Young
authors: SY
authors: Han
authors: Jiyoung Lee, Sung Wook Lee, Sang Young Han, Yang Hyun Baek, Su Young Kim, Hyo In Rhyou, Department of internal medicine, Dong-A University, College of Medicine, Busan 602-715, South Korea.
authors: Yang Hyun
authors: YH
authors: Baek
authors: Jiyoung Lee, Sung Wook Lee, Sang Young Han, Yang Hyun Baek, Su Young Kim, Hyo In Rhyou, Department of internal medicine, Dong-A University, College of Medicine, Busan 602-715, South Korea.
authors: Su Young
authors: SY
authors: Kim
authors: Jiyoung Lee, Sung Wook Lee, Sang Young Han, Yang Hyun Baek, Su Young Kim, Hyo In Rhyou, Department of internal medicine, Dong-A University, College of Medicine, Busan 602-715, South Korea.
authors: Hyo In
authors: HI
authors: Rhyou
mesh_terms: D001650:Bile Duct Neoplasms / Q000473:pathology* / Q000628:therapy; D001653:Bile Ducts, Intrahepatic / Q000473:pathology*; D001706:Biopsy; D018281:Cholangiocarcinoma / Q000556:secondary* / Q000628:therapy; D049448:Cholangiopancreatography, Magnetic Resonance; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000556:secondary* / Q000628:therapy; D018482:Muscle, Skeletal / Q000473:pathology*; D010166:Palliative Care; D049268:Positron-Emission Tomography; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Adenocarcinoma; Intrahepatic cholangiocarcinoma; Skeletal muscle metastasis