title: Primary Aspergillus sellar abscess simulating pituitary tumor in immunocompetent patient.
abstract: A 55-year-old woman presented with headache, dizziness, and decreased visual acuity. Magnetic resonance imaging revealed a sellar mass with sphenoid sinus extension. The result of hormone showed an obviously high prolactin (815 ng/mL). The mass was resected and diagnosed with aspergillosis pathologically. Postoperatively, the level of prolactin dramatically decreased, and the patient received medical treatment with voriconazole and caspofungin. During a 6-month follow-up, the patient's headache and dizziness disappeared, and visual acuity improved. Therefore, aspergillus sellar abscess could result in hyperprolactinemia and should be considered in the differential diagnosis of a sellar mass, even in immunocompetent patients. A combination of surgery and antifungal therapy could reduce the hyperprolactinemia and improve symptoms.
authors: From the Departments of *Neurosurgery and †Neurology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China.
authors: Taohui
authors: T
authors: Ouyang
authors: Na
authors: N
authors: Zhang
authors: Long
authors: L
authors: Wang
authors: Jiantong
authors: J
authors: Jiao
authors: Yiqing
authors: Y
authors: Zhao
authors: Zheng
authors: Z
authors: Li
authors: Jian
authors: J
authors: Chen
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D000935:Antifungal Agents / Q000627:therapeutic use*; D001228:Aspergillosis / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D001230:Aspergillus / Q000302:isolation & purification*; D003937:Diagnosis, Differential; D004322:Drainage / Q000379:methods*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010900:Pituitary Diseases / Q000601:surgery; D010902:Pituitary Gland / Q000382:microbiology*; D010911:Pituitary Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
chemical_list: D000935:Antifungal Agents