title: Neoadjuvant denosumab for extensive giant cell tumor in os ischium: a case report.
authors: Departments of Orthopedic Surgery , Leiden University Medical Center, Leiden , the Netherlands.
authors: Lizz
authors: L
authors: van der Heijden
authors: Michiel A J
authors: MA
authors: van de Sande
authors: Pancras C W
authors: PC
authors: Hogendoorn
authors: Hans
authors: H
authors: Gelderblom
authors: P D Sander
authors: PD
authors: Dijkstra
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D000069448:Denosumab; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D006801:Humans; D007512:Ischium / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D010027:Osteotomy; D053245:RANK Ligand / Q000037:antagonists & inhibitors*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D053245:RANK Ligand; C505688:TNFSF11 protein, human; D000069448:Denosumab