title: Haemoglobin-based oxygen carriers: indications and future applications.
abstract: This article describes current oxygen-carrying solutions, four new products and new indications to increase the benefit/risk ratio of haemoglobin-based oxygen carriers compared to blood. Indications include when blood is not available, if blood is contaminated, is refused or contraindicated, and for organ preservation.
authors: Associate Professor in the Department of Anesthesiology, Department of Anesthesiology, Shock Trauma Anesthesiology Research Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
authors: Mary
authors: M
authors: Njoku
authors: Deidre
authors: D
authors: St Peter
authors: Colin F
authors: CF
authors: Mackenzie
mesh_terms: D000740:Anemia / Q000628:therapy*; D001802:Blood Substitutes / Q000627:therapeutic use*; D006454:Hemoglobins / Q000627:therapeutic use*; D006470:Hemorrhage / Q000628:therapy*; D006801:Humans; D008301:Maleimides; D011092:Polyethylene Glycols
chemical_list: D001802:Blood Substitutes; D006454:Hemoglobins; D008301:Maleimides; C529085:OxyVita; C509893:PolyHeme; C493836:maleimide-polyethylene glycol-modified hemoglobin, MP4; C557204:polynitroxylated pegylated hemoglobin; C096798:HBOC 201; D011092:Polyethylene Glycols