title: [Use of heparinized autologous blood for intraoperative rinsing and storage of vascular grafts].
abstract: In cerebral revascularization surgery in Japan, the preferred solution for rinsing and intraoperative storage of saphenous vein or radial artery grafts is a heparinized saline solution with albumin. On the other hand, most cardiac surgeons routinely use solutions of heparinized autologous blood during surgery. Here we used the latter type of solution for cerebral revascularization surgery and evaluated its efficacy.
  
  
  METHODS
  Since December 2011, we have used heparinized autologous blood for saphenous vein grafts during cerebral revascularization surgery. For this, 20mL of the whole blood was obtained from an arterial line;this blood was then mixed with 20mL of a heparinized saline solution containing 500IU of heparin and 40mg of papaverine hydrochloride. The saphenous vein was harvested using standard procedures and immersed in the autologous blood solution just before implantation.
  
  
  RESULTS
  Between December 2011 and March 2013, six revascularizations using saphenous vein grafts were performed using this solution. None of the anastomoses presented complications related to revascularization procedures, and all grafts were clearly present postoperatively.
  
  
  CONCLUSIONS
  There is still no evidence that the storage in autologous blood is superior to the use of a saline solution with albumin. However, the national health insurance does not cover the use of albumin products, which carries an additional cost. Furthermore, the autologous blood medium is a red-colored solution that indicates the presence of unfavorable graft leaks when the wall of the graft turns red.
  
  
  CONCLUSIONS
  We recommend the use of heparinized autologous blood for intraoperative rinsing and storage grafts.
authors: Department of Neurosurgery, Kobe University Graduate School of Medicine.
authors: Hidehito
authors: H
authors: Kimura
authors: Kohkichi
authors: K
authors: Hosoda
authors: Eiji
authors: E
authors: Kohmura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001804:Blood Transfusion, Autologous; D001807:Blood Vessel Prosthesis; D005260:Female; D006493:Heparin; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D017534:Radial Artery / Q000601:surgery; D012501:Saphenous Vein / Q000601:surgery*; D014021:Tissue Preservation; D058017:Vascular Grafting
chemical_list: D006493:Heparin