title: Diversified syntheses of multifunctionalized thiazole derivatives via regioselective and programmed C-H activation.
abstract: The sequential construction of diversified multifunctionalized thiazole derivatives through Pd-catalyzed regioselective C-H alkenylation has been accomplished. This versatile approach provides the diversified thiazole derivatives featuring orthogonal substitution patterns at the C-2, C-4 and C-5 positions from mono-substituted (2- or 4-substituted) thiazole derivatives or even more challenging simple thiazole.
authors: Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China. zshi@pku.edu.cn.
authors: Xiang-Wei
authors: XW
authors: Liu
authors: Jiang-Ling
authors: JL
authors: Shi
authors: Jiang-Bo
authors: JB
authors: Wei
authors: Chao
authors: C
authors: Yang
authors: Jia-Xuan
authors: JX
authors: Yan
authors: Kun
authors: K
authors: Peng
authors: Le
authors: L
authors: Dai
authors: Chen-Guang
authors: CG
authors: Li
authors: Bi-Qin
authors: BQ
authors: Wang
authors: Zhang-Jie
authors: ZJ
authors: Shi
mesh_terms: D002384:Catalysis; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D010165:Palladium / Q000737:chemistry; D013237:Stereoisomerism; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D009942:Organometallic Compounds; D013844:Thiazoles; D010165:Palladium