title: Squamous Cell Carcinoma With Chronic Osteomyelitis: A Case Report.
abstract: Squamous cell carcinoma is one of the most common human malignancies; however, it is uncommon in the lower extremity. These lesions require prompt surgical attention and a delay in diagnosis can be harmful to the patient. We present a case report of squamous cell carcinoma with chronic osteomyelitis in a patient without diabetes. Definitive treatment included a transtibial amputation and metastatic workup was negative for active malignancy. Surgeons who treat chronic wounds should be cognizant of the potential for malignant degeneration.
  
  
  METHODS
  Therapeutic, Level IV: Case report.
authors: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania monacosj2@upmc.edu.
authors: Spencer J
authors: SJ
authors: Monaco
authors: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
authors: Kyle
authors: K
authors: Pearson
authors: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
authors: Dane K
authors: DK
authors: Wukich
mesh_terms: D000671:Amputation, Surgical; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery*; D002908:Chronic Disease; D006365:Heel / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000209:etiology* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery
keywords: amputation and limb salvage; bone; diagnostic and therapeutic techniques; nonhealing ulcer; osteomyelitis; wound care