title: Resting state Rolandic mu rhythms are related to activity of sympathetic component of autonomic nervous system in healthy humans.
abstract: We tested the hypothesis of a relationship between heart rate variability (HRV) and Rolandic mu rhythms in relaxed condition of resting state. Resting state eyes-closed electroencephalographic (EEG) and electrocardiographic (ECG) data were recorded (10-20 System) in 42 healthy adults. EEG rhythms of interest were high-frequency alpha (10.5-13Hz) and low-frequency beta (13-20Hz), which are supposed to form Rolandic mu rhythms. Rolandic and occipital (control) EEG sources were estimated by LORETA software. Results showed a statistically significant (p<0.05, corrected) negative correlation across all subjects between Rolandic cortical sources of low-frequency beta rhythms and the low-frequency band power (LF, 0.04-0.15Hz) of tachogram spectrum as an index of HRV. The lower the amplitude of Rolandic sources of low-frequency beta rhythms (as a putative sign of activity of somatomotor cortex), the higher the LF band power of tachogram spectrum (as a putative sign of sympathetic activity). This effect was specific as there was neither a similar correlation between these EEG rhythms and high-frequency band power of tachogram spectrum (as a putative sign of parasympathetic vagal activity) neither between occipital sources of low-frequency beta rhythms (as a putative sign of activity of visual cortex) and LF band power of tachogram spectrum. These results suggest that Rolandic low-frequency beta rhythms are related to sympathetic activity regulating heart rate, as a dynamic neurophysiologic oscillatory mechanism sub-serving the interaction between brain neural populations involved in somatomotor control and brain neural populations regulating ANS signals to heart for on-going homeostatic adaptations.
authors: Dept. of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
authors: Antonio Ivano
authors: AI
authors: Triggiani
authors: Dept. of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
authors: Anna
authors: A
authors: Valenzano
authors: IRCCS San Raffaele Pisana, Rome, Italy.
authors: Claudio
authors: C
authors: Del Percio
authors: IRCCS SDN, Naples, Italy.
authors: Nicola
authors: N
authors: Marzano
authors: IRCCS SDN, Naples, Italy; Department of Studies of Institutions and Territorial Systems, University of Naples Parthenope, Naples, Italy.
authors: Andrea
authors: A
authors: Soricelli
authors: Dept. of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
authors: Annamaria
authors: A
authors: Petito
authors: Dept. of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
authors: Antonello
authors: A
authors: Bellomo
authors: Brain Dynamics, Cognition and Complex Systems Research Center, Istanbul Kultur University, Istanbul, Turkey.
authors: Erol
authors: E
authors: Başar
authors: Dept. of Neuroscience, United Hospitals of Foggia, Foggia, Italy.
authors: Ciro
authors: C
authors: Mundi
authors: Dept. of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
authors: Giuseppe
authors: G
authors: Cibelli
authors: IRCCS San Raffaele Pisana, Rome, Italy; Dept. of Physiology and Pharmacology, University of Rome "La Sapienza", Rome, Italy. Electronic address: claudio.babiloni@uniroma1.it.
authors: Claudio
authors: C
authors: Babiloni
mesh_terms: D000293:Adolescent; D000328:Adult; D058256:Brain Waves / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology*; D004562:Electrocardiography; D004569:Electroencephalography; D004585:Electrooculography; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D012146:Rest; D013057:Spectrum Analysis; D018709:Statistics, Nonparametric; D013564:Sympathetic Nervous System / Q000502:physiology*; D055815:Young Adult
keywords: Autonomic Nervous System; EEG; Heart Rate Variability; LORETA; Mu Rhythms; Rolandic Rhythms