title: Recurrent pregnancy loss: evaluation and treatment.
abstract: Recurrent pregnancy loss (RPL) is a multifactorial condition. Approximately half of patients with RPL will have no explanation for their miscarriages. De novo chromosome abnormalities are common in sporadic and recurrent pregnancy loss. Testing for embryonic abnormalities can provide an explanation for the miscarriage in many cases and prognostic information. Regardless of the cause of RPL, patients should be reassured that the prognosis for live birth with an evidence-based approach is excellent for most patients. The authors review current evidence for the evaluation and treatment of RPL and explore the proposed use of newer technology for patients with RPL.
authors: Pacific NW Fertility and IVF Specialists, Seattle, WA, USA; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Washington School of Medicine, Seattle, WA, USA.
authors: Lora
authors: L
authors: Shahine
authors: Division of Reproductive Endocrinology and Infertility, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: rlathi@stanford.edu.
authors: Ruth
authors: R
authors: Lathi
mesh_terms: D000026:Abortion, Habitual / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000175:diagnosis*; D002869:Chromosome Aberrations / Q000196:embryology*; D020964:Embryo Loss / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D005260:Female; D005817:Genetic Counseling; D020022:Genetic Predisposition to Disease; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011379:Prognosis; D002581:Uterine Cervical Incompetence / Q000175:diagnosis* / Q000503:physiopathology
keywords: Recurrent embryonic loss; Recurrent fetal loss; Recurrent miscarriage; Recurrent pregnancy loss