title: [Approaches potentiating cardioprotective effect of ambulatory physical training in patients with ischemic heart disease and multivessel coronary artery involvement after coronary stenting].
abstract: Cardiorehabilitation of patients with multivessel coronary lesions is an obligatory component of ambulatory stage of care. With the aim of potentiating cardioprotective and antiischemic impact of rehabilitative preventive measures in 36 patients with ischemic heart disease (IHD) and multivessel coronary artery involvement who had undergone percutaneous coronary intervention we studied cardioprotective and antiischemic effect of long-term (24 weeks) administration of 70 mg/day trimetazidine in combination with moderate intensity physical training with the use of distance surveillance by a physician. The chosen therapeutic approach in patients with residual ischemia after incomplete anatomical revascularization provided early persistent formation of cardioprotective and antiischemic effect proven by increase of tolerance to physical exercise, improvement of diastolic function, and positive dynamics of both ECG parameters and biochemical markers of myocardial ischemia.
authors: N P
authors: NP
authors: Liamina
authors: E V
authors: EV
authors: Kotel'nikova
authors: E A
authors: EA
authors: Biziaeva
authors: É S
authors: ÉS
authors: Karpova
mesh_terms: D002316:Cardiotonic Agents / Q000008:administration & dosage; D003331:Coronary Vessels / Q000503:physiopathology / Q000601:surgery; D004452:Echocardiography / Q000379:methods; D004562:Electrocardiography / Q000379:methods; D005081:Exercise Therapy / Q000379:methods*; D017079:Exercise Tolerance; D005260:Female; D018575:Home Care Services, Hospital-Based / Q000458:organization & administration; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D062645:Percutaneous Coronary Intervention / Q000379:methods / Q000534:rehabilitation*; D011446:Prospective Studies; D012426:Russia; D012720:Severity of Illness Index; D015607:Stents; D016896:Treatment Outcome; D014292:Trimetazidine / Q000008:administration & dosage*; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D002316:Cardiotonic Agents; D014665:Vasodilator Agents; D014292:Trimetazidine