title: The UCSC Ebola Genome Portal.
abstract: BACKGROUND
  With the Ebola epidemic raging out of control in West Africa, there has been a flurry of research into the Ebola virus, resulting in the generation of much genomic data.
  
  
  METHODS
  In response to the clear need for tools that integrate multiple strands of research around molecular sequences, we have created the University of California Santa Cruz (UCSC) Ebola Genome Browser, an adaptation of our popular UCSC Genome Browser web tool, which can be used to view the Ebola virus genome sequence from GenBank and nearly 30 annotation tracks generated by mapping external data to the reference sequence. Significant annotations include a multiple alignment comprising 102 Ebola genomes from the current outbreak, 56 from previous outbreaks, and 2 Marburg genomes as an outgroup; a gene track curated by NCBI; protein annotations curated by UniProt and antibody-binding epitopes curated by IEDB. We have extended the Genome Browser's multiple alignment color-coding scheme to distinguish mutations resulting from non-synonymous coding changes, synonymous changes, or changes in untranslated regions.
  
  
  CONCLUSIONS
  Our Ebola Genome portal at http://genome.ucsc.edu/ebolaPortal/ links to the Ebola virus Genome Browser and an aggregate of useful information, including a collection of Ebola antibodies we are curating.
authors: CBSE, University of California Santa Cruz, Santa Cruz, California, USA.
authors: Maximilian
authors: M
authors: Haeussler
authors: CBSE, University of California Santa Cruz, Santa Cruz, California, USA.
authors: Donna
authors: D
authors: Karolchik
authors: CBSE, University of California Santa Cruz, Santa Cruz, California, USA.
authors: Hiram
authors: H
authors: Clawson
authors: CBSE, University of California Santa Cruz, Santa Cruz, California, USA.
authors: Brian J
authors: BJ
authors: Raney
authors: CBSE, University of California Santa Cruz, Santa Cruz, California, USA.
authors: Kate R
authors: KR
authors: Rosenbloom
authors: CBSE, University of California Santa Cruz, Santa Cruz, California, USA.
authors: Pauline A
authors: PA
authors: Fujita
authors: Genomics Institute, University of California Santa Cruz, Santa Cruz, California, USA.
authors: Angie S
authors: AS
authors: Hinrichs
authors: Matthew L
authors: ML
authors: Speir
authors: CBSE, University of California Santa Cruz, Santa Cruz, California, USA.
authors: Chris
authors: C
authors: Eisenhart
authors: CBSE, University of California Santa Cruz, Santa Cruz, California, USA.
authors: Ann S
authors: AS
authors: Zweig
authors: CBSE, University of California Santa Cruz, Santa Cruz, California, USA.
authors: David
authors: D
authors: Haussler
authors: CBSE, University of California Santa Cruz, Santa Cruz, California, USA.
authors: W James
authors: WJ
authors: Kent
keywords: EBOV; ebola; ebolavirus; genome analysis; genomics