title: Nisin as a Food Preservative: Part 2: Antimicrobial Polymer Materials Containing Nisin.
abstract: Nisin is the only bacteriocin approved as a food preservative because of its antibacterial effectiveness and its negligible toxicity for humans. Typical problems encountered when nisin is directly added to foods are mainly fat adsorption leading to activity loss, heterogeneous distribution in the food matrix, inactivation by proteolytic enzymes, and emergence of resistance in normally sensitive bacteria strains. To overcome these problems, nisin can be immobilized in solid matrices that must act as diffusional barriers and allow controlling its release rate. This strategy allows maintaining a just sufficient nisin concentration at the food surface. The design of such antimicrobial materials must consider both bacterial growth kinetics but also nisin release kinetics. In this review, nisin incorporation in polymer-based materials will be discussed and special emphasis will be on the applications and properties of antimicrobial food packaging containing this bacteriocin.
authors: a Laboratoire BioDyMIA (Bioingénierie et Dynamique Microbienne aux Interfaces Alimentaires), Université de Lyon, Université Lyon 1 - ISARA Lyon, Equipe Mixte d'Accueil n°3733 , IUT Lyon 1, Bourg en Bresse , France.
authors: Adem
authors: A
authors: Gharsallaoui
authors: a Laboratoire BioDyMIA (Bioingénierie et Dynamique Microbienne aux Interfaces Alimentaires), Université de Lyon, Université Lyon 1 - ISARA Lyon, Equipe Mixte d'Accueil n°3733 , IUT Lyon 1, Bourg en Bresse , France.
authors: Catherine
authors: C
authors: Joly
authors: a Laboratoire BioDyMIA (Bioingénierie et Dynamique Microbienne aux Interfaces Alimentaires), Université de Lyon, Université Lyon 1 - ISARA Lyon, Equipe Mixte d'Accueil n°3733 , IUT Lyon 1, Bourg en Bresse , France.
authors: Nadia
authors: N
authors: Oulahal
authors: a Laboratoire BioDyMIA (Bioingénierie et Dynamique Microbienne aux Interfaces Alimentaires), Université de Lyon, Université Lyon 1 - ISARA Lyon, Equipe Mixte d'Accueil n°3733 , IUT Lyon 1, Bourg en Bresse , France.
authors: Pascal
authors: P
authors: Degraeve
mesh_terms: D000464:Alginates; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000032:analysis*; D002482:Cellulose; D055598:Chemical Phenomena; D004355:Drug Stability; D005516:Food Microbiology; D018857:Food Packaging / Q000295:instrumentation*; D005519:Food Preservation; D005520:Food Preservatives; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D008089:Listeria monocytogenes; D009561:Nisin / Q000032:analysis* / Q000737:chemistry*; D011108:Polymers / Q000032:analysis*
chemical_list: D000464:Alginates; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D005520:Food Preservatives; D006603:Hexuronic Acids; D011108:Polymers; D009561:Nisin; D020723:Glucuronic Acid; D002482:Cellulose
keywords: Nisin; activation process; antimicrobial packaging; biopolymers; effectiveness evaluation; synthetic polymers