title: Prevalence of human papilloma virus infection in patients with male accessory gland infection.
abstract: The frequency of human papillomavirus (HPV) infection in the semen of patients with male accessory gland infection (MAGI) was evaluated. One hundred infertile patients with MAGI were classified into group A: patients with an inflammatory MAGI (n = 48) and group B: patients with a microbial form (n = 52). Healthy age-matched fertile men (34.0 ± 4.0 years) made up the control group (n = 20). Amplification of HPV DNA was carried out by HPV-HS Bio nested polymerase chain reaction for the detection of HPV DNA sequences within the L1 ORF. Ten patients in group A (20.8%) and 15 patients in group B (28.8%) had a HPV infection; two controls (10.0%) had HPV infection. Patients with MAGI had a significantly higher frequency of HPV infection compared with controls; patients with a microbial MAGI had significantly higher frequency of HPV infection compared with patients with an inflammatory form (both P < 0.05). Patients with MAGI and HPV had a slight, but significantly lower sperm progressive motility and normal morphology compared with patients with MAGI HPV-negative (P < 0.05). Elevated frequency of HPV infection occurred in patients with MAGI, suggesting that HPV should be investigated in the diagnostic work-up of these patients.
authors: Section of Andrology, Endocrinology and Internal Medicine, Department of Clinical and Experimental Medicine. Electronic address: sandrolavignera@unict.it.
authors: S
authors: S
authors: La Vignera
authors: Section of Andrology, Endocrinology and Internal Medicine, Department of Clinical and Experimental Medicine.
authors: E
authors: E
authors: Vicari
authors: Section of Andrology, Endocrinology and Internal Medicine, Department of Clinical and Experimental Medicine.
authors: R A
authors: RA
authors: Condorelli
authors: Clinical Virology Unit, A.O.U. 'Policlinico-Vittorio Emanuele', University of Catania, 95123 Catania, Italy.
authors: C
authors: C
authors: Franchina
authors: Clinical Virology Unit, A.O.U. 'Policlinico-Vittorio Emanuele', University of Catania, 95123 Catania, Italy.
authors: G
authors: G
authors: Scalia
authors: Department of Urology, University of Catania, 95123 Catania, Italy.
authors: G
authors: G
authors: Morgia
authors: Dipartimento di Scienze per la Promozione della Salute e Materno Infantile "G. d'Alessandro", University of Palermo, 90100 Palermo, Italy.
authors: A
authors: A
authors: Perino
authors: Dipartimento di Scienze per la Promozione della Salute e Materno Infantile "G. d'Alessandro", University of Palermo, 90100 Palermo, Italy.
authors: R
authors: R
authors: Schillaci
authors: Section of Andrology, Endocrinology and Internal Medicine, Department of Clinical and Experimental Medicine.
authors: A E
authors: AE
authors: Calogero
mesh_terms: D000328:Adult; D015897:Comorbidity; D005832:Genital Diseases, Male / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D007248:Infertility, Male / Q000821:virology*; D007249:Inflammation / Q000453:epidemiology* / Q000821:virology; D008297:Male; D027383:Papillomaviridae / Q000302:isolation & purification; D030361:Papillomavirus Infections / Q000453:epidemiology*; D015995:Prevalence; D011472:Prostatitis / Q000453:epidemiology* / Q000821:virology; D012661:Semen / Q000821:virology; D055101:Semen Analysis; D013081:Sperm Motility
keywords: HPV; MAGI; Prevalence