title: Effect of vaccination against bovine herpesvirus 1 with inactivated gE-negative marker vaccines on the health of dairy cattle herds.
abstract: The aim of this study was to estimate the effect of the bovine herpesvirus 1 (BHV-1) vaccination on herd health and production in BHV-1 infected Estonian dairy cattle herds. Seven herds vaccinated with inactivated gE-negative BHV-1 marker vaccines and seven matched non-vaccinated herds were selected. In vaccinated herds the calving interval was on average 7.01 days shorter compared to that in the non-vaccinated herds (coef=-7.01, 95% CI=-11.98, -2.03, p=0.008) during the study period (2007-2012). In non-vaccinated herds the insemination index had an increasing trend (coef(log scale)=0.03, 95% CI=-0.003, 0.06, p=0.054) and the first service conception rate decreased (coef=-2.19, 95% CI=-3.91, -0.47, p=0.015), whereas no significant changes occurred in vaccinated herds. Average yearly milk yield per cow increased (coef=145.30, 95% CI=-6.11, 296.71, p=0.065) and length of the dry period decreased in BHV-1 vaccinated herds (coef(log scale)=-0.02, 95% CI=-0.04, 0.004, p=0.056) compared to non-vaccinated herds during the study years. Youngstock and the cow culling rate due to respiratory disease was significantly lower in vaccinated herds compared to non-vaccinated herds (coef=-0.29, 95% CI=-0.47, -0.11, p=0.003 and coef=-0.15, 95% CI=-0.29, -0.007, p=0.043, respectively). These results suggest that vaccination against BHV-1 is associated with herd health and productivity.
authors: Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Kreutzwaldi 62, Tartu 51014, Estonia. Electronic address: Kerli.Raaperi@emu.ee.
authors: Kerli
authors: K
authors: Raaperi
authors: Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Kreutzwaldi 62, Tartu 51014, Estonia.
authors: Toomas
authors: T
authors: Orro
authors: Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Kreutzwaldi 62, Tartu 51014, Estonia.
authors: Arvo
authors: A
authors: Viltrop
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology / Q000517:prevention & control*; D003612:Dairying; D004957:Estonia / Q000453:epidemiology; D005260:Female; D006304:Health Status; D006566:Herpesviridae Infections / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary*; D007242:Herpesvirus 1, Bovine / Q000276:immunology*; D022283:Herpesvirus Vaccines / Q000627:therapeutic use*; D016014:Linear Models; D008892:Milk; D011795:Surveys and Questionnaires; D014611:Vaccination; D022581:Vaccines, Marker
chemical_list: D022283:Herpesvirus Vaccines; D022581:Vaccines, Marker
keywords: Bovine herpesvirus 1; Herd health; Reproduction; Respiratory disease; Vaccination