title: Interpretability of the PedsQL™ Gastrointestinal Symptoms Scales and Gastrointestinal Worry Scales in Pediatric Patients With Functional and Organic Gastrointestinal Diseases.
abstract: OBJECTIVE
  The present study investigates the clinical interpretability of the Pediatric Quality of Life Inventory™ (PedsQL™) Gastrointestinal Symptoms Scales and Worry Scales in pediatric patients with functional gastrointestinal disorders or organic gastrointestinal diseases in comparison with healthy controls.
  
  
  METHODS
  The PedsQL™ Gastrointestinal Scales were completed by 587 patients with gastrointestinal disorders/diseases and 685 parents, and 513 healthy children and 337 parents. Minimal important difference (MID) scores were derived from the standard error of measurement (SEM). Cut-points were derived based on one and two standard deviations (SDs) from the healthy reference means.
  
  
  RESULTS
  The percentages of patients below the scales' cut-points were significantly greater than the healthy controls (most p values ≤ .001). Scale scores 2 SDs from the healthy reference means were within the range of scores for pediatric patients with a gastrointestinal disorder. MID values were generated using the SEM.
  
  
  CONCLUSIONS
  The findings support the clinical interpretability of the new PedsQL™ Gastrointestinal Symptoms Scales and Worry Scales.
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah jvarni@arch.tamu.edu.
authors: James W
authors: JW
authors: Varni
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
authors: Cristiane B
authors: CB
authors: Bendo
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
authors: Robert J
authors: RJ
authors: Shulman
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
authors: Mariella M
authors: MM
authors: Self
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
authors: Samuel
authors: S
authors: Nurko
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
authors: James P
authors: JP
authors: Franciosi
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
authors: Miguel
authors: M
authors: Saps
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
authors: Shehzad
authors: S
authors: Saeed
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
authors: George M
authors: GM
authors: Zacur
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
authors: Chelsea
authors: C
authors: Vaughan Dark
authors: Department of Pediatrics, College of Medicine, Department of Landscape Architecture and Urban Planning, College of Architecture, Texas A&M University, Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais, Department of Pediatrics, Baylor College of Medicine, Children's Nutrition Research Center, Texas Children's Hospital, Department of Psychiatry and Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Harvard Medical School, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Division of Gastroenterology, Hepatology and Nutrition, Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Department of Psychology, Texas A&M University, and Department of Pediatric Gastroenterology, Primary Children's Hospital, University of Utah.
authors: John F
authors: JF
authors: Pohl
mesh_terms: D000293:Adolescent; D001007:Anxiety / Q000150:complications / Q000175:diagnosis* / Q000523:psychology*; D001294:Attitude to Health; D002648:Child; D002675:Child, Preschool; D005260:Female; D005767:Gastrointestinal Diseases / Q000150:complications / Q000175:diagnosis* / Q000523:psychology*; D006801:Humans; D008297:Male; D010290:Parents; D010372:Pediatrics; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires / Q000592:standards*
keywords: PedsQL.; gastrointestinal symptoms; minimal important difference; patient-reported outcomes