title: [Sleep and autonomic function: sleep related breathing disorders in Parkinson's disease and related disorders].
abstract: In patients with multiple system atrophy (MSA), sleep related breathing disorders (SRBD), including obstructive and central sleep apnea, vocal cord abductor paralysis and dysrhythmic breathing pattern, are frequently observed. SRBD may have a considerable impact on variation of autonomic nervous activity during sleep. The previous studies correlated upper airway muscle dysfunction related parkinsonism with increased prevalence of SRBD in patients with Parkinson's disease (PD). However, recently, the clinical significance of SRBD and its impact on sleepiness and disease severity have been debated. In this review, we discuss sleep and autonomic function, especially, SRBD in PD and related disorders, including the previous studies from our department.
authors: Department of Neurology, Dokkyo Medical University.
authors: Keisuke
authors: K
authors: Suzuki
authors: Masayuki
authors: M
authors: Miyamoto
authors: Tomoyuki
authors: T
authors: Miyamoto
authors: Koichi
authors: K
authors: Hirata
mesh_terms: D001341:Autonomic Nervous System / Q000503:physiopathology; D001342:Autonomic Nervous System Diseases / Q000209:etiology; D006801:Humans; D019578:Multiple System Atrophy / Q000150:complications / Q000503:physiopathology; D010300:Parkinson Disease / Q000150:complications* / Q000503:physiopathology; D020182:Sleep Apnea, Central / Q000209:etiology; D020181:Sleep Apnea, Obstructive / Q000209:etiology*; D012895:Sleep, REM / Q000502:physiology