title: Age and Obesity are Independent Predictors of Bile Duct Injuries in Patients Undergoing Laparoscopic Cholecystectomy.
abstract: BACKGROUND
  Iatrogenic bile duct injury is a serious complication of cholecystectomy. The aim of this study was to assess predictors of bile duct injury using a national database.
  
  
  METHODS
  The Nationwide Inpatient Sample (2010-2012) was queried for laparoscopic cholecystectomy. We used a) diagnoses for bile duct injury and b) bile duct injury repair procedure codes as a surrogate marker for bile duct injuries.
  
  
  RESULTS
  A total of 1,015 patients had bile duct injury. The mean age was 58.2 ± 19.7 years, 53.5 % were males, and median Charlson co-morbidity score was 2 [2, 3]. Multivariate analysis revealed morbid obesity [2.8 (2.1-4.3); p = 0.03] and age >65 [1.5 (1.05-2.1); p = 0.01] as the independent predictors for bile duct injury in patients undergoing cholecystectomy.
  
  
  CONCLUSIONS
  Our study finds a new association between obesity, aging, and bile duct injuries which has never been reported in literature before.
authors: Division of HepatoPancreaticoBiliary Surgery, University of Arizona, Tucson, AZ, USA, haziz@surgery.arizona.edu.
authors: Hassan
authors: H
authors: Aziz
authors: Viraj
authors: V
authors: Pandit
authors: Bellal
authors: B
authors: Joseph
authors: Tun
authors: T
authors: Jie
authors: Evan
authors: E
authors: Ong
mesh_terms: D000367:Age Factors; D000368:Aged; D001649:Bile Duct Diseases / Q000601:surgery; D001652:Bile Ducts / Q000293:injuries*; D017081:Cholecystectomy, Laparoscopic / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D007431:Intraoperative Complications / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D012307:Risk Factors