title: Small Bowel Bacterial Overgrowth Associated with Persistence of Abdominal Symptoms in Children Treated with a Proton Pump Inhibitor.
abstract: Small bowel bacterial overgrowth (SBBO) was diagnosed in 22.5% of 40 children treated for 3 months with a proton pump inhibitor (PPI). Compared with those without SBBO, children with SBBO had higher frequency of abdominal pain, bloating, eructation, and flatulence. Patients with gastrointestinal symptoms after PPI treatment should be evaluated for SBBO rather than empirically prolonging PPI therapy.
authors: Department of Pediatrics, Pediatric Gastroenterology, Hepatology, and Nutrition, Medical University of Gdansk, Gdansk, Poland. Electronic address: aszatewicz@gmail.com.
authors: Agnieszka
authors: A
authors: Sieczkowska
authors: Department of Pediatrics, Pediatric Gastroenterology, Hepatology, and Nutrition, Medical University of Gdansk, Gdansk, Poland.
authors: Piotr
authors: P
authors: Landowski
authors: Department of Hygiene and Epidemiology, Medical University of Gdansk, Gdansk, Poland.
authors: Pawel
authors: P
authors: Zagozdzon
authors: Department of Pediatrics, Pediatric Gastroenterology, Hepatology, and Nutrition, Medical University of Gdansk, Gdansk, Poland.
authors: Barbara
authors: B
authors: Kaminska
authors: Section of Pediatric Gastroenterology, Hepatology, and Transplantation, Hospital Italiano, Buenos Aires, Argentina.
authors: Carlos
authors: C
authors: Lifschitz
mesh_terms: D015746:Abdominal Pain / Q000175:diagnosis*; D000293:Adolescent; D001944:Breath Tests; D002648:Child; D002675:Child, Preschool; D005260:Female; D005414:Flatulence; D005767:Gastrointestinal Diseases; D006801:Humans; D006859:Hydrogen / Q000737:chemistry; D007421:Intestine, Small / Q000382:microbiology*; D008297:Male; D064307:Microbiota; D011446:Prospective Studies; D054328:Proton Pump Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D054328:Proton Pump Inhibitors; D006859:Hydrogen