title: A fatal case of primary cutaneous gamma-delta T-cell lymphoma complicated by HLH and cardiac amyloidosis.
abstract: Gamma-delta T-cell lymphomas (GD-TCL) are rare and rapidly fatal neoplasms that are often associated with Hemophagocytic Lymphohistiocytosis (HLH), a syndrome of fevers, cytopenias, and multiorgan failure that often leads to a rapid death. We report the first case demonstrating an association between GD-TCL, HLH, and cardiac amyloidosis, presenting a novel mechanism for rapid deterioration in these patients.
authors: Department of Medicine, Yale University School of Medicine New Haven, Connecticut.
authors: Juliet Fraser
authors: JF
authors: Gibson
authors: Hematopathology, Department of Pathology, Yale University School of Medicine New Haven, Connecticut.
authors: Lucy
authors: L
authors: Kapur
authors: Department of Medicine, Yale University School of Medicine New Haven, Connecticut.
authors: Joseph
authors: J
authors: Sokhn
authors: Hematopathology, Department of Pathology, Yale University School of Medicine New Haven, Connecticut.
authors: Mina
authors: M
authors: Xu
authors: Hematology and Bone Marrow Transplantation, Yale University School of Medicine New Haven, Connecticut.
authors: Francine M
authors: FM
authors: Foss
keywords: Amyloidosis; cutaneous T-cell lymphoma; gamma–delta; hemophagocytic lymphohistiocytosis; primary cutaneous gamma–delta T-cell lymphoma