title: Tracer diffusion inside fibrinogen layers.
abstract: We investigate the obstructed motion of tracer (test) particles in crowded environments by carrying simulations of two-dimensional Gaussian random walk in model fibrinogen monolayers of different orientational ordering. The fibrinogen molecules are significantly anisotropic and therefore they can form structures where orientational ordering, similar to the one observed in nematic liquid crystals, appears. The work focuses on the dependence between level of the orientational order (degree of environmental crowding) of fibrinogen molecules inside a layer and non-Fickian character of the diffusion process of spherical tracer particles moving within the domain. It is shown that in general particles motion is subdiffusive and strongly anisotropic, and its characteristic features significantly change with the orientational order parameter, concentration of fibrinogens, and radius of a diffusing probe.
authors: M. Smoluchowski Institute of Physics and M. Kac Complex Systems Research Center, Jagiellonian University, 30-059 Kraków, Reymonta 4, Poland.
authors: Michał
authors: M
authors: Cieśla
authors: M. Smoluchowski Institute of Physics and M. Kac Complex Systems Research Center, Jagiellonian University, 30-059 Kraków, Reymonta 4, Poland.
authors: Ewa
authors: E
authors: Gudowska-Nowak
authors: Departament de Quimica Fisica, Universitat de Barcelona, Marti i Franques 1, E-08028 Barcelona, Spain.
authors: Francesc
authors: F
authors: Sagués
authors: Institut für Physik, Humboldt Universität zu Berlin, Newtonstr. 15, 12489 Berlin, Germany.
authors: Igor M
authors: IM
authors: Sokolov