title: Use of steroids for facial nerve paralysis after parotidectomy: A systematic review.
abstract: OBJECTIVE
  To systematically review the literature to assess the efficacy of corticosteroids in treating post-parotidectomy facial nerve palsy (FNP).
  
  
  METHODS
  We searched the Cochrane library, EMBASE and MEDLINE (from inception to 2014) for studies assessing the use of corticosteroids in post-parotidectomy FNP. Studies were assessed for inclusion and quality. Data was extracted from included studies.
  
  
  RESULTS
  Two randomised controlled trials met the inclusion criteria. One study assessed the use of dexamethasone and the other prednisolone. None of the studies demonstrated a significant difference in the outcome of FNP post-parotidectomy with the use of corticosteroids vs no therapy. The majority of FNP post-parotidectomy is transient. Preoperative factors (size of tumour and malignancy), intraoperative factors (extent of parotidectomy and integrity of facial nerve at the end of the operation) are important in determining prognosis of FNP if it does occur.
  
  
  CONCLUSIONS
  Corticosteroids do not appear to improve FNP prognosis post-parotidectomy. Further studies assessing patients by cohort and with long term follow-up are required to increase scientific evidence.
authors: Kiran Varadharajan, Department of ENT, St. George's Hospital, SW17 0QT London, United Kingdom.
authors: Kiran
authors: K
authors: Varadharajan
authors: Kiran Varadharajan, Department of ENT, St. George's Hospital, SW17 0QT London, United Kingdom.
authors: Issa
authors: I
authors: Beegun
authors: Kiran Varadharajan, Department of ENT, St. George's Hospital, SW17 0QT London, United Kingdom.
authors: Niall
authors: N
authors: Daly
keywords: Adrenal cortex hormones; Facial paralysis; Parotid diseases; Steroids