title: Associative episodic memory and recollective processes in childhood temporal lobe epilepsy.
abstract: While the current literature on children suffering from temporal lobe epilepsy (CTLE) mostly focuses on material-related episodic memory deficits according to seizure-onset lateralization, the present study examined associative episodic memory according to the type of information to memorize (e.g., factual, spatial, and sequential) and further investigated subjective and objective recollection. Eleven children with left temporal lobe epilepsy (LTLE), 10 children with right temporal lobe epilepsy (RTLE), among whom 9 displayed hippocampal sclerosis (HS), and 42 healthy controls completed the WHAT-WHEN-WHERE protocol (Guillery-Girard et al., 2013). Group comparisons were first conducted according to the affected side and second according to the underlying pathology. Results showed associative memory impairments in patients irrespective of the affected side. Moreover, this study revealed that HS is particularly deleterious to associative and subjective recollection in CTLE. In addition, this study emphasizes the need for assessing episodic memory in childhood TLE beyond material specificity.
authors: UMR-S1077, INSERM, Université de Caen Basse-Normandie, Ecole Pratique des Hautes Etudes, CHU de Caen, France; INSERM U1129, Paris, France; Université Paris Descartes, PRES Sorbonne Paris Cité, France; CEA, Gif sur Yvette, France; UNIACT, Neuropsin, CEA-Sacley, France. Electronic address: sylvie.martins@neuropsy-enfant.com.
authors: Sylvie
authors: S
authors: Martins
authors: UMR-S1077, INSERM, Université de Caen Basse-Normandie, Ecole Pratique des Hautes Etudes, CHU de Caen, France.
authors: Bérengère
authors: B
authors: Guillery-Girard
authors: UMR-S1077, INSERM, Université de Caen Basse-Normandie, Ecole Pratique des Hautes Etudes, CHU de Caen, France.
authors: Patrice
authors: P
authors: Clochon
authors: INSERM U1129, Paris, France; Université Paris Descartes, PRES Sorbonne Paris Cité, France; CEA, Gif sur Yvette, France; UNIACT, Neuropsin, CEA-Sacley, France; Fondation Ophtalmologique Rothschild, Neurosurgery Unit, Paris, France.
authors: Christine
authors: C
authors: Bulteau
authors: INSERM U1129, Paris, France; Université Paris Descartes, PRES Sorbonne Paris Cité, France; CEA, Gif sur Yvette, France; UNIACT, Neuropsin, CEA-Sacley, France.
authors: Lucie
authors: L
authors: Hertz-Pannier
authors: INSERM U1129, Paris, France; Université Paris Descartes, PRES Sorbonne Paris Cité, France; CEA, Gif sur Yvette, France; UNIACT, Neuropsin, CEA-Sacley, France.
authors: Catherine
authors: C
authors: Chiron
authors: UMR-S1077, INSERM, Université de Caen Basse-Normandie, Ecole Pratique des Hautes Etudes, CHU de Caen, France.
authors: Francis
authors: F
authors: Eustache
authors: INSERM U1129, Paris, France; Université Paris Descartes, PRES Sorbonne Paris Cité, France; CEA, Gif sur Yvette, France; Fondation Ophtalmologique Rothschild, Neurosurgery Unit, Paris, France.
authors: Isabelle
authors: I
authors: Jambaqué
mesh_terms: D000293:Adolescent; D001245:Association Learning / Q000502:physiology*; D002648:Child; D004833:Epilepsy, Temporal Lobe / Q000150:complications / Q000503:physiopathology*; D005260:Female; D007839:Functional Laterality; D006624:Hippocampus / Q000473:pathology*; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000209:etiology / Q000503:physiopathology*; D061212:Memory, Episodic; D011939:Mental Recall / Q000502:physiology*; D012598:Sclerosis / Q000473:pathology; D013702:Temporal Lobe / Q000473:pathology
keywords: Associative memory; Hippocampus; Objective memory; Pediatrics; Subjective recollection; Temporal lobe epilepsy