title: Ivacaftor therapy in siblings with cystic fibrosis-the potential implications of Itraconazole in dosage and efficacy.
authors: Cork Adult Cystic Fibrosis Centre, Dept. of Medicine, Cork University Hospital/University College Cork, Wilton, Cork, Ireland.
authors: M J
authors: MJ
authors: Harrison
authors: Cork Adult Cystic Fibrosis Centre, Dept. of Medicine, Cork University Hospital/University College Cork, Wilton, Cork, Ireland.
authors: N J
authors: NJ
authors: Ronan
authors: Cork Adult Cystic Fibrosis Centre, Dept. of Medicine, Cork University Hospital/University College Cork, Wilton, Cork, Ireland.
authors: K A
authors: KA
authors: Khan
authors: Cork Adult Cystic Fibrosis Centre, Dept. of Medicine, Cork University Hospital/University College Cork, Wilton, Cork, Ireland.
authors: G
authors: G
authors: O'Callaghan
authors: Cork Adult Cystic Fibrosis Centre, Dept. of Medicine, Cork University Hospital/University College Cork, Wilton, Cork, Ireland.
authors: D M
authors: DM
authors: Murphy
authors: Cork Adult Cystic Fibrosis Centre, Dept. of Medicine, Cork University Hospital/University College Cork, Wilton, Cork, Ireland. Electronic address: b.plant@ucc.ie.
authors: B J
authors: BJ
authors: Plant
mesh_terms: D000328:Adult; D000627:Aminophenols / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology*; D003550:Cystic Fibrosis / Q000188:drug therapy* / Q000235:genetics; D065692:Cytochrome P-450 CYP3A Inhibitors / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004336:Drug Antagonism; D004791:Enzyme Inhibitors; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D009154:Mutation; D015363:Quinolones / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D035781:Siblings
chemical_list: D000627:Aminophenols; D000935:Antifungal Agents; D065692:Cytochrome P-450 CYP3A Inhibitors; D004791:Enzyme Inhibitors; D015363:Quinolones; C545203:ivacaftor; D017964:Itraconazole