title: Determination and dissipation of fipronil and its metabolites in peanut and soil.
abstract: In this study, a modified quick, easy, cheap, effective, rugged, and safe (QuEChERS) method was established for the extraction and cleanup of fipronil and its three metabolites (fipronil solfone, sulfide, and desulfinyl) in peanut kernel, shell, straw, seedling, and soil samples, and liquid chromatography-tandem mass spectrometry (LC-MS/MS) was used for analysis. The average recoveries were 66-116% at the level of 0.001-0.1 mg/kg with the RSD <19%, and the limit of detection was 0.3 ng/g for all matrices. The dissipation experiment results demonstrated that fipronil dissipated more rapidly in peanut seedling than in soil, with half-lives of <1 day in peanut seedling and 32-57 days in soil depending on the soil pH. The final residues at harvest of peanut kernels were all below 0.02 mg/kg, whereas in peanut shell and straw, the total highest residues were 0.99 and 0.30 mg/kg, respectively. Fipronil-desulfinyl and fipronil-sulfone were the highest residue metabolites in peanut plant (seedling and straw) and soil samples, respectively.
authors: †College of Science, China Agricultural University, Beijing 100193, China.|§Institute of Quality Standards and Testing Technology for Agro-Products, Xinjiang Academy of Agricultural Sciences, Xinjiang 830091, China.
authors: Minghui
authors: M
authors: Li
authors: †College of Science, China Agricultural University, Beijing 100193, China.
authors: Puyu
authors: P
authors: Li
authors: †College of Science, China Agricultural University, Beijing 100193, China.|#College of Plant Protection, Henan Agricultural University, Zhengzhou 450002, Henan, China.
authors: Lin
authors: L
authors: Wang
authors: †College of Science, China Agricultural University, Beijing 100193, China.
authors: Mengyuan
authors: M
authors: Feng
authors: †College of Science, China Agricultural University, Beijing 100193, China.
authors: Lijun
authors: L
authors: Han
mesh_terms: D010367:Arachis / Q000737:chemistry* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D006207:Half-Life; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism; D007700:Kinetics; D010573:Pesticide Residues / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism; D011720:Pyrazoles / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism; D012989:Soil Pollutants / Q000737:chemistry* / Q000378:metabolism; D053719:Tandem Mass Spectrometry / Q000379:methods*
chemical_list: D007306:Insecticides; D010573:Pesticide Residues; D011720:Pyrazoles; D012989:Soil Pollutants; C082360:fipronil
keywords: LC-MS/MS; QuEChERS; fipronil; metabolites; peanut; residues