title: Cell tropism and molecular epidemiology of Anaplasma platys-like strains in cats.
abstract: Bacterial species of the genus Anaplasma are tick transmitted pathogens that negatively impact on animal productions and generate veterinary and public health concerns. This paper reports the identification, molecular characterization and phylogeny of novel unclassified A. platys-like strains in cats. Interestingly, these novel strains are closely related to conspecific strains recently identified in ruminants, and significantly differ from A. platys. A. platys-like strains in cats, unlike ruminants strains, show tropism for platelets. Results have implications in the diagnostic scenario of animal anaplasmosis and provide background for reconstructing the evolutionary history of species genetically related to A. platys.
authors: Department of Veterinary Medicine, University of Sassari, Italy.
authors: R
authors: R
authors: Zobba
authors: Department of Veterinary Medicine, University of Sassari, Italy.
authors: A G
authors: AG
authors: Anfossi
authors: Department of Veterinary Medicine, University of Sassari, Italy.
authors: S
authors: S
authors: Visco
authors: Department of Veterinary Medicine, University of Sassari, Italy.
authors: F
authors: F
authors: Sotgiu
authors: Department of Veterinary Medicine, University of Sassari, Italy.
authors: C
authors: C
authors: Dedola
authors: Department of Veterinary Medicine, University of Sassari, Italy.
authors: M L
authors: ML
authors: Pinna Parpaglia
authors: Department of Veterinary Medical Science, Bologna, Italy.
authors: M
authors: M
authors: Battilani
authors: Department of Veterinary Medicine, University of Sassari, Italy.
authors: M
authors: M
authors: Pittau
authors: Department of Veterinary Medicine, University of Sassari, Italy. Electronic address: alberti@uniss.it.
authors: A
authors: A
authors: Alberti
mesh_terms: D000709:Anaplasma / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D000712:Anaplasmosis / Q000453:epidemiology* / Q000382:microbiology; D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics; D001483:Base Sequence; D002371:Cat Diseases / Q000453:epidemiology* / Q000382:microbiology; D002415:Cats; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA / Q000662:veterinary; D018523:Tropism
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial
keywords: Anaplasmataceae; Bacterial evolution; Diversity; Molecular diagnosis; Tick borne diseases