title: The potential effects of Spirulina platensis (Arthrospira platensis) on tissue protection of Nile tilapia (Oreochromis niloticus) through estimation of P53 level.
abstract: The current study was designed to investigate the potential effect of Spirulina platensis, Arthrospira platensis, (SP) on tissue protection of Nile tilapia (Oreochromis niloticus) through estimation of P53 level. Five isonitrogenous and isocaloric rations containing graded levels of dried SP 5, 7.5,10, 15, and 20 g/kg diet were fed separately to five equal groups of O. niloticus fingerlings, additional control group was assigned for 3 months. Liver samples were separately collected from each group by the end of each month. The expression level of P53 showed a substantial decrease among the treated groups in a time-dependent manner. It is therefore advisable to incorporate SP in diets for tissue protection and antioxidant effects in cultured O. niloticus.
authors: Department of Fish Diseases and Management, Faculty of Veterinary Medicine, Cairo University, 12211 Giza, Egypt.
authors: Mai D
authors: MD
authors: Ibrahem
authors: Department of Biochemistry, Faculty of Veterinary Medicine, Cairo University, 12211 Giza, Egypt.
authors: Marwa A
authors: MA
authors: Ibrahim
keywords: Oreochromis niloticus; P53 expression level; Spirulina platensis (SP); Tissue protection