title: Complete genome sequence of Streptomyces vietnamensis GIMV4.0001 T, a genetically manipulable producer of the benzoisochromanequinone antibiotic granaticin.
abstract: We report the complete genome sequence of Streptomyces vietnamensis GIMV4.0001(T), a new and genetically manipulable producer of the benzoisochromanequinone antibiotic granaticin, whose unique sugar attachment pattern in structure has drawn much attention among chemical and biochemical researchers. The genome of S. vietnamensis GIMV4.0001(T) consists of one linear chromosome (8,867,142 bp, 72.09% G+C content) and one linear megaplasmid named pSVL1 (286,635 bp, 69.04% G+C content), encoding a total of 7356 protein coding genes. Twenty-nine gene clusters for secondary metabolites were predicted on the chromosome.
authors: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou 510075, China.
authors: Ming-Rong
authors: MR
authors: Deng
authors: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou 510075, China.
authors: Jun
authors: J
authors: Guo
authors: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou 510075, China.
authors: Lian-Ying
authors: LY
authors: Ma
authors: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou 510075, China.
authors: Yan-Xuan
authors: YX
authors: Li
authors: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou 510075, China.
authors: Guang-Da
authors: GD
authors: Feng
authors: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou 510075, China.
authors: Cui-Yun
authors: CY
authors: Mo
authors: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou 510075, China. Electronic address: zhuhh@gdim.cn.
authors: Hong-Hui
authors: HH
authors: Zhu
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001483:Base Sequence; D002876:Chromosomes, Bacterial; D016680:Genome, Bacterial; D008969:Molecular Sequence Data; D009285:Naphthoquinones / Q000378:metabolism; D013302:Streptomyces / Q000235:genetics* / Q000378:metabolism*; D000095622:Benzoisochromanequinones
chemical_list: D000900:Anti-Bacterial Agents; D009285:Naphthoquinones; C009811:granaticin; D000095622:Benzoisochromanequinones
keywords: Genome sequence; Granaticin; Streptomyces