title: Half-dose alteplase for sub-massive pulmonary embolism directed by emergency department point-of-care ultrasound.
abstract: This report describes a patient with sub-massive pulmonary embolism (PE) who was successfully treated with half-dose thrombolytics guided by the use of point-of-care (POC) ultrasound. In this case, POC ultrasound was the only possible imaging since computed tomography was contraindicated. POC ultrasound demonstrated a deep vein thrombosis and evidence of cardiac strain. In situations or locations where definitive imaging is unobtainable, POC ultrasound can help diagnose submassive PE and direct the use of half-dose tissue plasminogen activator.
authors: University of Arizona, Department of Emergency Medicine, Tucson, Arizona.
authors: Richard
authors: R
authors: Amini
authors: Ohio State University, Department of Emergency Medicine, Columbus Ohio.
authors: Ashish R
authors: AR
authors: Panchal
authors: Ohio State University, Department of Emergency Medicine, Columbus Ohio.
authors: David
authors: D
authors: Bahner
authors: University of Arizona, Department of Emergency Medicine, Tucson, Arizona.
authors: Srikar
authors: S
authors: Adhikari
mesh_terms: D004636:Emergency Service, Hospital; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D019095:Point-of-Care Systems; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage* / Q000627:therapeutic use; D018084:Ultrasonography, Interventional
chemical_list: D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator