title: [Hemorrhagic cystitis due to adenovirus in a renal transplant recipient: the first reported case in black Africa in a setting of a very beginning of a kidney transplantation program and review of the literature].
abstract: Viral infections are an important complication of transplantation. Polyomavirus are the commonest viruses that infect the renal allograft. Herpes virus nephropathy has also been described. In the past 15 years, adenovirus nephritis has emerged as a potentially life-threatening disease in renal transplant patients in developed countries. Most of the papers devoted to adenovirus nephritis are reported cases. The fate of such patients in resources-limited countries is not known. Herein, we describe the clinical, biological and prognostic findings of a black African transplanted patient with adenoviral hemorrhagic cystitis. This case is the very first of its kind reported in black Africa in a setting of a start of a renal transplantation pilot project. The patient is a 54-year-old man admitted at the nephrology service for gross haematuria and fever occurred 1 month after kidney transplantation. The diagnosis of adenoviral hemorrhagic cystitis has been suspected because the patient has displayed recurrent conjunctivitis and gastroenteritis well before transplantation, which was then confirmed by the real-time polymerase chain reaction performed on the blood. Conservatory measures associated with immunosuppression reduction have permitted the discontinuation of haematuria. This case has been discussed in regard of the epidemiology, the diagnosis, the treatment, the evolution and the prognosis of the adenoviral infection in the renal transplant patient. A review of the literature has been performed subsequently.
authors: Service de néphrologie et hémodialyse, CHU de Yopougon, Abidjan, Côte d'Ivoire. Electronic address: cnackoundoun66@hotmail.fr.
authors: Clément
authors: C
authors: Ackoundou-N'Guessan
authors: Unité pilote de transplantation rénale, service d'urologie, institut de cardiologie, CHU de Treichville, Km 1 boulevard de Marseille, BP V 206 Abidjan, Abidjan, Côte d'Ivoire.
authors: Noël
authors: N
authors: Coulibaly
authors: Service de néphrologie et hémodialyse, CHU de Yopougon, Abidjan, Côte d'Ivoire.
authors: Cyr Monley
authors: CM
authors: Guei
authors: Service d'anesthésie et de réanimation, CHU de Yopougon, Abidjan, Côte d'Ivoire.
authors: Denis
authors: D
authors: Aye
authors: Service d'anesthésie et de réanimation, CHU de Cocody, université Félix Houphouët-Boigny, Abidjan, Cocody, BP V 32 Abidjan, Abidjan, Côte d'Ivoire.
authors: Francis Yapi
authors: FY
authors: N'guessan
authors: Service d'anatomie pathologique, CHU de Cocody, université Félix Houphouët-Boigny, Abidjan, Cocody, BP V 32 Abidjan, Abidjan, Côte d'Ivoire.
authors: Justin Kouame
authors: JK
authors: N'Dah
authors: Service de néphrologie et hémodialyse, CHU de Yopougon, Abidjan, Côte d'Ivoire.
authors: Delphine Amélie
authors: DA
authors: Lagou
authors: Service de néphrologie et hémodialyse, CHU de Yopougon, Abidjan, Côte d'Ivoire.
authors: Mélanie Weu
authors: MW
authors: Tia
authors: Service de néphrologie et hémodialyse, CHU de Yopougon, Abidjan, Côte d'Ivoire.
authors: Pessa Albert
authors: PA
authors: Coulibaly
authors: Service de néphrologie et hémodialyse, CHU de Yopougon, Abidjan, Côte d'Ivoire.
authors: Sita
authors: S
authors: Nzoue
authors: Service de néphrologie et hémodialyse, CHU de Yopougon, Abidjan, Côte d'Ivoire.
authors: Serges
authors: S
authors: Konan
authors: Service de néphrologie et hémodialyse, CHU de Yopougon, Abidjan, Côte d'Ivoire.
authors: Daze Apollinaire
authors: DA
authors: Gnionsahe
mesh_terms: D000257:Adenoviridae Infections / Q000150:complications* / Q000175:diagnosis; D044383:Black People; D007560:Cote d'Ivoire; D003556:Cystitis / Q000821:virology*; D006417:Hematuria / Q000821:virology*; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D066027:Transplant Recipients
keywords: Adenovirus; Adénovirus; Black African; Cystite hémorragique; Hemorrhagic cystitis; Noir Africain; Renal transplant patient; Transplanté rénal