title: Sterile cyst formation after intrathecal stem cell transplant for Parkinson's disease: A case presentation and literature review.
abstract: In recent years, fetal or autologous stem cell transplant for the treatment of Parkinson's disease (PD) has been practiced in a few medical organizations. However, the potential complications related to the growth of allograft tissue have not yet been well described apart from case reports. Here, we present a 42-year-old Saudi male who suffered from early onset Parkinson's disease. He sought medical care in China and received autologous intrathecal stem cell transplantation. He did not demonstrate any significant improvement. A few months later, the patient went back to China and underwent fetal cell transplantation into the left hemisphere and a second stem cell transplantation intrathecally. He presented with seizures and had a left frontal brain cyst. The cyst was drained and contained clear fluid. All cultures were negative. He had an uneventful recovery.
authors: Specialty Internal Medicine Unit, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia. Electronic address: jaffar.tawfiq@jhah.com.
authors: Jaffar A
authors: JA
authors: Al-Tawfiq
authors: Specialty Internal Medicine Unit, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
authors: Ramzi W
authors: RW
authors: Banda
authors: Specialty Internal Medicine Unit, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.
authors: Jihad
authors: J
authors: Ghandour
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D003560:Cysts / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D053686:Fetal Stem Cells / Q000637:transplantation*; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D010300:Parkinson Disease / Q000628:therapy*; D033581:Stem Cell Transplantation / Q000009:adverse effects*; D014182:Transplantation, Autologous
keywords: Brain abscess; Brain cyst; Fetal stem cell; Parkinsonism; Transplant