title: Impact of a rapid microarray-based assay for identification of positive blood cultures for treatment optimization for patients with streptococcal and enterococcal bacteremia.
abstract: Implementation of the Verigene Gram-positive blood culture test led to reductions in time to acceptable antibiotic overall (1.9 versus 13.2 h, respectively; P=0.04) and time to appropriate antibiotic for patients with vancomycin-resistant Enterococcus (4.2 versus 43.7 h; P=0.006) and viridans group Streptococcus (0.2 versus 7.1 h; P=0.02).
authors: Department of Pharmacy, University of North Carolina Health Care, Chapel Hill, North Carolina, USA Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA.
authors: Danya G
authors: DG
authors: Roshdy
authors: McLendon Clinical Laboratories, University of North Carolina Health Care, Chapel Hill, North Carolina, USA.
authors: Anthony
authors: A
authors: Tran
authors: Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, USA.
authors: Nicholas
authors: N
authors: LeCroy
authors: Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
authors: Donglin
authors: D
authors: Zeng
authors: Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA.
authors: Fang-shu
authors: FS
authors: Ou
authors: Department of Pharmacy, University of North Carolina Health Care, Chapel Hill, North Carolina, USA.
authors: Lindsay M
authors: LM
authors: Daniels
authors: School of Medicine, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
authors: David J
authors: DJ
authors: Weber
authors: McLendon Clinical Laboratories, University of North Carolina Health Care, Chapel Hill, North Carolina, USA.
authors: Kevin
authors: K
authors: Alby
authors: McLendon Clinical Laboratories, University of North Carolina Health Care, Chapel Hill, North Carolina, USA School of Medicine, Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina, USA melissa.miller@unchealth.unc.edu.
authors: Melissa B
authors: MB
authors: Miller
mesh_terms: D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000175:diagnosis* / Q000382:microbiology; D016022:Case-Control Studies; D016983:Enterococcus / Q000302:isolation & purification*; D016908:Gram-Positive Bacterial Infections / Q000097:blood / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D008875:Middle Aged; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D013291:Streptococcus / Q000302:isolation & purification*