title: [A second case of white lentiginosis].
abstract: BACKGROUND
  White lentiginosis is characterized by white guttate macules with a typical histological structure: lentiginosis hyperplasia with hypopigmentation.
  
  
  METHODS
  A 23-year-old woman, from Algeria, presented with white macules from 5 years ago. Few women in her family had the same trouble. Cutaneous examination revealed diffused white little macules. Histological examination showed a lentiginous hyperplasia of the epidermis, with elongated club-shaped rete ridges and an unusual loss of pigmentation.
  
  
  CONCLUSIONS
  Different diagnosis should be discussed with disseminated leucoderma macules. Nevertheless, the only one which corresponds with our case is the white lentiginosis. To our knowledge, it is the first case described since Grosshans et al. in 1994. Our patient is a descendant of the original case's family. This new case appears to confirm the genetic origin of the disorder and suggests autosomal dominant or X-linked inheritance.
authors: Service d'anatomo-pathologie, hôpitaux civils de Colmar, 39, avenue de la Liberté, 68024 Colmar cedex, France. Electronic address: chloe.moulinas@gmail.com.
authors: C
authors: C
authors: Moulinas
authors: Service de dermatologie, hôpitaux civils de Colmar, 39, avenue de la Liberté, 68024 Colmar cedex, France.
authors: S
authors: S
authors: Banea
authors: Service de dermatologie, hôpitaux civils de Colmar, 39, avenue de la Liberté, 68024 Colmar cedex, France.
authors: G
authors: G
authors: De Cambourg
authors: Cabinet de dermatologie, 4, place des Martyrs-de-la-Résistance, 68000 Colmar, France.
authors: H
authors: H
authors: Bochaton
authors: Service d'anatomo-pathologie, hôpitaux civils de Colmar, 39, avenue de la Liberté, 68024 Colmar cedex, France.
authors: M-C
authors: MC
authors: Tortel
authors: Clinique de dermatologie, hôpitaux universitaires de Strasbourg, 1, place de l'hôpital, 67091 Strasbourg cedex, France.
authors: B
authors: B
authors: Cribier
authors: Service de dermatologie, hôpitaux civils de Colmar, 39, avenue de la Liberté, 68024 Colmar cedex, France.
authors: A
authors: A
authors: Mahé
mesh_terms: D000462:Algeria / Q000208:ethnology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D007911:Lentigo / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D012880:Skin Pigmentation; D055815:Young Adult
keywords: Genodermatosis; Génodermatose; Hypopigmentation; Lentiginose; Lentiginosis; Leucoderma; Leucodermie