title: Improvement of erectile function by a combination of French maritime pine bark and roburins with aminoacids.
abstract: OBJECTIVE
  Primary objective of the study was the evaluation of effects of a combination of plant extracts and aminoacids on erectile function (ED).
  
  
  METHODS
  The study was performed as a randomized, placebo-controlled, double-blind, cross-over study. 50 men with moderate ED received a combination of Pycnogenol®, roburins, L-arginine, L-citrulline or placebo. Sexual wellness was evaluated by the International Index of Erectile Function (IIEF).
  
  
  RESULTS
  Treatment over a period of one month restored erectile function to normal.
  
  
  CONCLUSIONS
  The combination offers an option for treatment of ED without unwanted effects.
authors: Institute of Pharmacy, University of Münster, Münster, Germany - rohdewa@uni-muenster.de.
authors: R
authors: R
authors: Stanislavov
authors: P
authors: P
authors: Rohdewald
mesh_terms: D000328:Adult; D001120:Arginine / Q000627:therapeutic use*; D001224:Aspartic Acid / Q000627:therapeutic use*; D002956:Citrulline / Q000627:therapeutic use; D018592:Cross-Over Studies; D004311:Double-Blind Method; D004338:Drug Combinations; D007172:Erectile Dysfunction / Q000188:drug therapy*; D005419:Flavonoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010410:Penile Erection / Q000187:drug effects*; D008517:Phytotherapy / Q000379:methods; D028223:Pinus; D010936:Plant Extracts / Q000627:therapeutic use*; D011788:Quality of Life; D029963:Quercus; D011795:Surveys and Questionnaires; D013634:Tannins / Q000627:therapeutic use*; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D004338:Drug Combinations; D005419:Flavonoids; D010936:Plant Extracts; D013634:Tannins; D014665:Vasodilator Agents; C553157:prelox; D002956:Citrulline; D001224:Aspartic Acid; C024070:pycnogenols; D001120:Arginine