title: Ameloblastic fibroma in an alpine chamois (Rupicapra rupicapra).
abstract: Spontaneous odontogenic tumors are neoplasms characterized by a mixed odontogenic ectomesenchymal and odontogenic epithelial origin; they are rare in both humans and animals. A 3-year-old male Alpine Chamois (Rupicapra rupicapra) was found dead in north-west Italy, and was referred for the necropsy to the Department of Veterinary Sciences of the University of Turin (Italy). At the external examination a 10 × 8 cm, exophytic, red-pink, smooth, firm and ulcerated mass was observed on the inferior lip. Histologically the tumor was characterized by spindle shaped cells arranged in bundles in an abundant hyaline matrix. Multifocal and rare chords of odontogenic epithelium mixed with rare melanocytes that penetrate the neoplasia were visible. Immunohistochemistry showed a clear cytokeratin positivity of epithelial clusters. Macroscopical, histological and immunohistochemical findings were consistent with a diagnosis of locally infiltrative ameloblastic fibroma. To our best knowledge, this is the first report of this tumor in a wild ungulate and in Alpine Chamois.
authors: Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Largo Paolo Braccini 2, Grugliasco 10095, Italy. Electronic address: frineeleonora.scaglione@unito.it.
authors: F E
authors: FE
authors: Scaglione
authors: Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Largo Paolo Braccini 2, Grugliasco 10095, Italy.
authors: S
authors: S
authors: Iussich
authors: Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Largo Paolo Braccini 2, Grugliasco 10095, Italy.
authors: D
authors: D
authors: Grande
authors: Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Largo Paolo Braccini 2, Grugliasco 10095, Italy.
authors: M
authors: M
authors: Carpignano
authors: Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Largo Paolo Braccini 2, Grugliasco 10095, Italy.
authors: L
authors: L
authors: Chiappino
authors: Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Largo Paolo Braccini 2, Grugliasco 10095, Italy.
authors: A
authors: A
authors: Sereno
authors: Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Largo Paolo Braccini 2, Grugliasco 10095, Italy.
authors: E
authors: E
authors: Ferroglio
authors: Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Largo Paolo Braccini 2, Grugliasco 10095, Italy.
authors: E
authors: E
authors: Bollo
mesh_terms: D000564:Ameloblastoma / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D000835:Animals, Wild; D005350:Fibroma / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D007558:Italy; D008297:Male; D048608:Rupicapra
keywords: Alpine Chamois; Ameloblastic fibroma; Rupicapra rupicapra