title: A novel mutation in ICOS presenting as hypogammaglobulinemia with susceptibility to opportunistic pathogens.
authors: Division of Immunology, Boston Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors: Janet
authors: J
authors: Chou
authors: Division of Immunology, Boston Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors: Michel J
authors: MJ
authors: Massaad
authors: Division of Immunology, Boston Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors: Brittney
authors: B
authors: Cangemi
authors: Division of Immunology, Boston Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors: Wayne
authors: W
authors: Bainter
authors: Division of Immunology, Boston Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors: Craig
authors: C
authors: Platt
authors: Division of Immunology, Boston Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors: Yousef R
authors: YR
authors: Badran
authors: Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors: Bram P
authors: BP
authors: Raphael
authors: Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, Mass.
authors: Daniel S
authors: DS
authors: Kamin
authors: Department of Pathology, Boston Children's Hospital and Beth Israel Deaconess Medical Center, Boston, Mass.
authors: Jeffrey D
authors: JD
authors: Goldsmith
authors: Division of Hematology-Oncology, Boston Children's Hospital, Boston, Mass; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Mass.
authors: Sung-Yun
authors: SY
authors: Pai
authors: Faculty of Medicine, Department of Pediatrics, Kuwait University, Kuwait City, Kuwait.
authors: Waleed
authors: W
authors: Al-Herz
authors: Division of Immunology, Boston Children's Hospital and the Department of Pediatrics, Harvard Medical School, Boston, Mass. Electronic address: Raif.Geha@childrens.harvard.edu.
authors: Raif S
authors: RS
authors: Geha
mesh_terms: D000361:Agammaglobulinemia / Q000150:complications / Q000235:genetics* / Q000276:immunology / Q000628:therapy; D002675:Child, Preschool; D003092:Colitis / Q000150:complications / Q000235:genetics* / Q000276:immunology / Q000628:therapy; D015870:Gene Expression; D020022:Genetic Predisposition to Disease; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D060889:Inducible T-Cell Co-Stimulator Protein / Q000235:genetics* / Q000276:immunology; D008213:Lymphocyte Activation; D008297:Male; D009154:Mutation; D009894:Opportunistic Infections / Q000150:complications / Q000235:genetics* / Q000276:immunology / Q000628:therapy; D013601:T-Lymphocytes / Q000276:immunology* / Q000473:pathology
chemical_list: C556692:ICOS protein, human; D060889:Inducible T-Cell Co-Stimulator Protein