title: Bacterial histone-like proteins: roles in stress resistance.
abstract: Histone-like proteins (HLPs) are small and basic bacterial proteins that are associated with a nucleoid and play roles in maintaining DNA architecture and regulating DNA transactions such as replication, recombination/repair and transcription. The studies on HLPs from a variety of bacterial species in recent years are summarized in this mini-review. A recent study reported a novel DNA-binding protein (HP119) in Helicobacter pylori that shows some HLP features. It plays a large role in aiding bacterial stress resistance. We provide herein additional evidence that HP119 is a nucleoid-associated protein, and present some perspectives for future study.
authors: Department of Microbiology, University of Georgia, 815 Biological Sciences Building, Athens, GA, 30602, USA.
authors: Ge
authors: G
authors: Wang
authors: Department of Microbiology, University of Georgia, 815 Biological Sciences Building, Athens, GA, 30602, USA. rmaier@uga.edu.
authors: Robert J
authors: RJ
authors: Maier
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism / Q000648:ultrastructure; D004260:DNA Repair; D004261:DNA Replication; D004269:DNA, Bacterial / Q000235:genetics* / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000378:metabolism; D016480:Helicobacter pylori / Q000235:genetics* / Q000378:metabolism / Q000648:ultrastructure; D006657:Histones / Q000235:genetics* / Q000378:metabolism; D018716:Molecular Mimicry; D013312:Stress, Physiological / Q000235:genetics; D014158:Transcription, Genetic
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D004268:DNA-Binding Proteins; C031908:H-NS protein, bacteria; D006657:Histones
keywords: Helicobacter pylori; Histone-like proteins; Stress resistance