title: Prevalence of dyslipidemia in adolescents: comparison between definitions.
abstract: BACKGROUND
  The indiscriminate use of different diagnostic criteria for the definition of dyslipidemia may result in inaccurate interpretations, which could compromise diagnosis and therefore the therapeutic and prophylactic actions to be taken.
  
  
  OBJECTIVE
  To analyze possible differences in prevalence rates of dyslipidemia in adolescents based on three diagnostic definitions.
  
  
  METHODS
  A cross-sectional study was conducted of a representative sample of Brazilian adolescents between 11 and 16 years of age. Blood samples were collected from 1000 students (423 boys and 577 girls) to determine fasting total cholesterol (TC), HDL and LDL cholesterol, and triglycerides (TG). The prevalence of dyslipidemia was established according to three definitions: those of the National Cholesterol Education Program (NCEP), the Brazilian Society of Cardiology (BSC), and the National Health and Nutrition Examination Survey (NHANES).
  
  
  RESULTS
  Significant differences (p<0.01) were found between the diagnostic criteria for TC (BSC 38.3%; NCEP 11.2%; NHANES 4.8%), HDL cholesterol (BSC 30.0%; NCEP 15.8% NHANES 18.4%), LDL cholesterol (BSC and NCEP 10.8% and NHANES 5.9%), and TG (BSC and NCEP 4.7% and NHANES 1.3%). The overall prevalence of dyslipidemia was 61% (BSC), 28.6% (NCEP) and 24.2% (NHANES). Agreement rates varied significantly (kappa 0.15-0.90).
  
  
  CONCLUSIONS
  Although a high prevalence of dyslipidemia was observed in this study regardless of the diagnostic criteria used, the wide variation in rates highlights the need to establish a single definition with appropriate discriminatory power for adolescents.
authors: Study and Research Group in Metabolism, Nutrition, and Exercise GEPEMENE, State University of Londrina - UEL, Londrina, Brazil.
authors: Crisieli M
authors: CM
authors: Tomeleri
authors: Study and Research Group in Metabolism, Nutrition, and Exercise GEPEMENE, State University of Londrina - UEL, Londrina, Brazil.
authors: Enio R V
authors: ER
authors: Ronque
authors: Study and Research Group in Metabolism, Nutrition, and Exercise GEPEMENE, State University of Londrina - UEL, Londrina, Brazil. Electronic address: danilorpsilva@gmail.com.
authors: Danilo R P
authors: DR
authors: Silva
authors: Study and Research Group in Metabolism, Nutrition, and Exercise GEPEMENE, State University of Londrina - UEL, Londrina, Brazil.
authors: Crivaldo G
authors: CG
authors: Cardoso Júnior
authors: Scientific Research Group Related to Physical Activity (GICRAF), Laboratory of Investigation in Exercise (LIVE), Department of Physical Education, Center of Sciences and Technology, UNESP Univ Estadual Paulista, Presidente Prudente, Brazil.
authors: Rômulo A
authors: RA
authors: Fernandes
authors: Study and Research Group in Metabolism, Nutrition, and Exercise GEPEMENE, State University of Londrina - UEL, Londrina, Brazil.
authors: Denilson C
authors: DC
authors: Teixeira
authors: Department of Pathology, Clinical and Toxicological Analysis, Center of Health Sciences, University Hospital, State University of Londrina - UEL, Londrina, Brazil.
authors: Décio S
authors: DS
authors: Barbosa
authors: Department of Pathology, Clinical and Toxicological Analysis, Center of Health Sciences, University Hospital, State University of Londrina - UEL, Londrina, Brazil.
authors: Danielle
authors: D
authors: Venturini
authors: Department of Pathology, Clinical and Toxicological Analysis, Center of Health Sciences, University Hospital, State University of Londrina - UEL, Londrina, Brazil.
authors: Alessandra M
authors: AM
authors: Okino
authors: Department of Pathology, Clinical and Toxicological Analysis, Center of Health Sciences, University Hospital, State University of Londrina - UEL, Londrina, Brazil.
authors: Jair A
authors: JA
authors: Oliveira
authors: Study and Research Group in Metabolism, Nutrition, and Exercise GEPEMENE, State University of Londrina - UEL, Londrina, Brazil.
authors: Edilson S
authors: ES
authors: Cyrino
mesh_terms: D000293:Adolescent; D002648:Child; D003430:Cross-Sectional Studies; D050171:Dyslipidemias / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence
keywords: Aterosclerose; Atherosclerosis; Cardiovascular disease; Doenças cardiovasculares; Fatores de risco; Jovens; Risk factors; Youth