title: White coat hypertension and obstructive sleep apnea.
abstract: OBJECTIVE
  This study aimed to determine blood pressure characteristics and long-term progress in patients with white coat hypertension (WCH) and obstructive sleep apnea (OSA).
  
  
  METHODS
  Systolic blood pressure (SBP) and diastolic blood pressure (DBP) and sleep test results over a period of 26 months were analyzed from WCH patients with OSA (n = 28), WCH patients (n = 23), and healthy control subjects (n = 27).
  
  
  RESULTS
  At the end of observation, WCH patients with OSA presented significantly increased daytime and nighttime BP and lower diurnal difference of SBP (all Ps < 0.05) and the increased rate of "non-dipper" status (SBP 28.6 %, DBP 32.1 %) was significantly higher when compared with WCH and control groups (all Ps < 0.01). Sustained hypertension was observed in 42.8 % of the WCH patients with OSA, which was significantly higher than that in the WCH and control groups (Ps < 0.01) and was predicted by non-dipper status via 24-h ambulatory SBP/DBP monitoring (Ps < 0.05).
  
  
  CONCLUSIONS
  WCH may represent a prehypertension status, which could develop into sustained hypertension with OSA.
authors: Cardiovascular Center, Beijing Tong Ren Hospital, Capital University of Medical Sciences, 100730, Beijing, China. ellentmc2010@hotmail.com.
authors: Li
authors: L
authors: Li
authors: Cardiovascular Center, Beijing Tong Ren Hospital, Capital University of Medical Sciences, 100730, Beijing, China.
authors: Li-Zhu
authors: LZ
authors: Guo
authors: Cardiovascular Center, Beijing Tong Ren Hospital, Capital University of Medical Sciences, 100730, Beijing, China.
authors: Jie
authors: J
authors: Li
authors: Cardiovascular Center, Beijing Tong Ren Hospital, Capital University of Medical Sciences, 100730, Beijing, China.
authors: Ying
authors: Y
authors: Wang
authors: Cardiovascular Center, Beijing Tong Ren Hospital, Capital University of Medical Sciences, 100730, Beijing, China.
authors: Xin
authors: X
authors: Liu
authors: Cardiovascular Center, Beijing Tong Ren Hospital, Capital University of Medical Sciences, 100730, Beijing, China.
authors: Ya-Hui
authors: YH
authors: Lv
authors: Cardiovascular Center, Beijing Tong Ren Hospital, Capital University of Medical Sciences, 100730, Beijing, China.|Atrial Fibrillation Center, Cardiology Department, Beijing An Zhen Hospital, Capital University of Medical Sciences, 100029, Beijing, China.
authors: Chang-Sheng
authors: CS
authors: Ma
mesh_terms: D000328:Adult; D000368:Aged; D002940:Circadian Rhythm / Q000502:physiology; D003430:Cross-Sectional Studies; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology*; D059466:White Coat Hypertension / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology*
keywords: Blood pressure; Non-dipper; Obstructive sleep apnea; White coat hypertension