title: Germline-competent stem cell in avian species and its application.
abstract: Germ cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent stem cells have contributed to the generation of avian model systems and the conservation of avian genetic resources. In this review, we focus on previous studies on germline-competent stem cells from avian species, mainly chicken germline-competent stem cells, which have been well established and characterized. We discuss different sources of germline-competent stem cells and recent advances for the future applications in birds.
authors: Department of Agricultural Biotechnology, College of Agriculture and Life Sciences, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul-151 921, Korea.
authors: Jae Yong
authors: JY
authors: Han
authors: Hyung Chul
authors: HC
authors: Lee
authors: Tae Sub
authors: TS
authors: Park
mesh_terms: D053687:Adult Stem Cells / Q000166:cytology; D000818:Animals; D001717:Birds / Q000235:genetics*; D001756:Blastoderm / Q000166:cytology; D002454:Cell Differentiation / Q000235:genetics; D019070:Cell Lineage / Q000235:genetics*; D000066673:Cell Self Renewal / Q000235:genetics; D002645:Chickens / Q000235:genetics*; D053595:Embryonic Stem Cells / Q000166:cytology*; D005260:Female; D005854:Germ Cells / Q000166:cytology*; D066298:In Vitro Techniques; D008297:Male; D023421:Models, Animal; D039904:Pluripotent Stem Cells / Q000166:cytology*