title: Hydrothermal treatment of titanium alloys for the enhancement of osteoconductivity.
abstract: The surface wettability of implants is a crucial factor in their osteoconductivity because it influences the adsorption of cell-attached proteins onto the surface. In this study, a single-step hydrothermal surface treatment using distilled water at a temperature of 180°C for 3h was applied to titanium (Ti) and its alloys (Ti-6Al-4V, Ti-6Al-7Nb, Ti-29Nb-13Ta-4.6Zr, Ti-13Cr-1Fe-3Al; mass%) and compared with as-polished Ti implants and with implants produced by anodizing Ti in 0.1M of H3PO4 with applied voltages from 0V to 150V at a scanning rate of 0.1Vs(-1). The surface-treated samples were stored in a five time phosphate buffered saline (×5 PBS(-)) solution to prevent increasing the water contact angle (WCA) with time. The surface characteristics were evaluated using scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, Auger electron spectroscopy, surface roughness, and contact angle measurement using a 2μL droplet of distilled water. The relationship between WCA and osteoconductivity at various surface modifications was examined using in vivo tests. The results showed that a superhydrophilic surface with a WCA≤10° and a high osteoconductivity (RB-I) of up to 50% in the cortical bone part, about four times higher than the as-polished Ti and Ti alloys, were provided by the combination of the hydrothermal surface treatment and storage in ×5 of PBS(-).
authors: Department of Materials Science & Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan; Department of Mechanical Engineering, Manad State University (UNIMA), Indonesia. Electronic address: mzuldesmi@yahoo.com.
authors: Mansjur
authors: M
authors: Zuldesmi
authors: Department of Materials Science & Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan.
authors: Atsushi
authors: A
authors: Waki
authors: EcoTopia Science Institute, Nagoya University, Nagoya, Japan.
authors: Kensuke
authors: K
authors: Kuroda
authors: EcoTopia Science Institute, Nagoya University, Nagoya, Japan.
authors: Masazumi
authors: M
authors: Okido
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000502:physiology*; D008297:Male; D009556:Niobium; D056951:Photoelectron Spectroscopy; D051381:Rats; D017207:Rats, Sprague-Dawley; D013499:Surface Properties; D013635:Tantalum; D014025:Titanium; D014961:X-Ray Diffraction; D015040:Zirconium
chemical_list: C481486:Ti-29Nb-13Ta-4.6Zr alloy; D009556:Niobium; D013635:Tantalum; D015040:Zirconium; D014025:Titanium
keywords: Hydrophilic; Hydrothermal; In vivo; Osteoconductivity; Titanium alloys