title: Computerised clinical decision support for suspected PE.
abstract: This study aimed to determine the effect of an evidence-based clinical decision support (CDS) algorithm on the use and yield of CT pulmonary angiography (CTPA) and on outcomes of patients evaluated in the emergency department (ED) for suspected PE. The study included 1363 consecutive patients evaluated for suspected PE in an ED during 12 months before and 12 months after initiation of CDS use. Introduction of CDS was associated with decreased CTPA use (55% vs 49%; absolute difference (AD), 6.3%; 95% CI 1.0% to 11.6%; p=0.02). The use of CDS was associated with fewer symptomatic venous thromboembolic events during follow-up in patients with an initial negative diagnostic evaluation for PE (0.7% vs 3.2%; AD 2.5%; 95% CI 0.9% to 4.6%; p<0.01).
authors: Respiratory Department, Ramón y Cajal Hospital, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, and Alcala de Henares University, Madrid, Spain.
authors: David
authors: D
authors: Jiménez
authors: Radiology Department, Ramón y Cajal Hospital and Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain.
authors: Santiago
authors: S
authors: Resano
authors: Respiratory Department, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
authors: Remedios
authors: R
authors: Otero
authors: Respiratory Department, Ramón y Cajal Hospital, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, and Alcala de Henares University, Madrid, Spain.
authors: Carolina
authors: C
authors: Jurkojc
authors: Department of Internal Medicine, Ramón y Cajal Hospital and Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain.
authors: Ana Karina
authors: AK
authors: Portillo
authors: Emergency Department, Hospital Clínico, Madrid, Spain.
authors: Pedro
authors: P
authors: Ruiz-Artacho
authors: Emergency Department, Ramón y Cajal Hospital and Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain.
authors: Jesús
authors: J
authors: Corres
authors: Radiology Department, Ramón y Cajal Hospital and Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Madrid, Spain.
authors: Agustina
authors: A
authors: Vicente
authors: Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.
authors: Paul L
authors: PL
authors: den Exter
authors: Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.
authors: Menno V
authors: MV
authors: Huisman
authors: F. Edward Hebert School of Medicine, Uniformed Services University, Bethesda, USA.
authors: Lisa
authors: L
authors: Moores
authors: Divisions of Pulmonary and Critical Care Medicine and General Medical Sciences, Washington University School of Medicine, St. Louis, Missouri, USA.
authors: Roger D
authors: RD
authors: Yusen
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D000792:Angiography / Q000379:methods*; D020000:Decision Support Systems, Clinical; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: Pulmonary Embolism