title: Global warming and neurodegenerative disorders: speculations on their linkage.
abstract: Climate change is having considerable impact on biological systems. Eras of ice ages and warming shaped the contemporary earth and origin of creatures including humans. Warming forces stress conditions on cells. Therefore, cells evolved elaborate defense mechanisms, such as creation of heat shock proteins, to combat heat stress. Global warming is becoming a crisis and this process would yield an undefined increasing rate of neurodegenerative disorders in future decades. Since heat stress is known to have a degenerative effects on neurons and, conversely, cold conditions have protective effect on these cells, we hypothesize that persistent heat stress forced by global warming might play a crucial role in increasing neurodegenerative disorders.
authors: Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
authors: Laleh
authors: L
authors: Habibi
authors: Department of Biology, The University of Texas at San Antonio, San Antonio, TX, USA.
authors: George
authors: G
authors: Perry
authors: Nanotechnology Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran ; Division of Pediatric Cardiology, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA ; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, USA.
authors: Morteza
authors: M
authors: Mahmoudi
keywords: Global warming; Heat shock proteins; Neurodegenerative disorders