title: Evaluation of ischemic diabetic maculopathy with Fourier-domain optical coherence tomography and microperimetry.
abstract: OBJECTIVE
  To evaluate the efficacy of high-speed Fourier-domain optical coherence tomography (FD-OCT) and fundus microperimetry (MP-1) in identifying the anatomic and functional features of ischemic diabetic maculopathy.
  
  
  METHODS
  Prospective noninterventional study.
  
  
  METHODS
  Forty-two consecutive eyes (23 patients) with ischemic diabetic maculopathy and 40 normal eyes (25 control subjects) were included in this study.
  
  
  METHODS
  Best corrected visual acuity, ganglion cell complex (GCC) thickness measured with FD-OCT, and central light sensitivity recorded with MP-1 were evaluated.
  
  
  RESULTS
  GCC thickness and light sensitivity were significantly reduced in all affected eyes versus control eyes. logMAR BVCA was significantly correlated with mean macular sensitivity (R=0.783, R(2)=0.611).
  
  
  CONCLUSIONS
  GCC thickness and microperimetry integrated with fluorescein angiography could be a marker of retinal vascular abnormalities that is useful for the diagnosis of ischemic diabetic maculopathy.
authors: Eye Clinic, Department of Neurosciences, Reproductive Sciences, and Dentistry, University Naples Federico II, Naples, Italy. Electronic address: xgilda@hotmail.com.
authors: Gilda
authors: G
authors: Cennamo
authors: Eye Clinic, Department of Neurosciences, Reproductive Sciences, and Dentistry, University Naples Federico II, Naples, Italy.
authors: Elisabetta Chiariello
authors: EC
authors: Vecchio
authors: Eye Clinic, Department of Neurosciences, Reproductive Sciences, and Dentistry, University Naples Federico II, Naples, Italy.
authors: Marialuisa
authors: M
authors: Finelli
authors: Eye Clinic, Department of Neurosciences, Reproductive Sciences, and Dentistry, University Naples Federico II, Naples, Italy.
authors: Nunzio
authors: N
authors: Velotti
authors: Eye Clinic, Department of Neurosciences, Reproductive Sciences, and Dentistry, University Naples Federico II, Naples, Italy.
authors: Giuseppe
authors: G
authors: de Crecchio
mesh_terms: D000368:Aged; D003930:Diabetic Retinopathy / Q000175:diagnosis*; D005260:Female; D005451:Fluorescein Angiography; D005583:Fourier Analysis; D006801:Humans; D007511:Ischemia / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012165:Retinal Ganglion Cells / Q000473:pathology*; D012171:Retinal Vessels / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity / Q000502:physiology*; D058609:Visual Field Tests / Q000379:methods*