title: Primary adenoid cystic carcinoma of the trachea: a report of two cases and literature review.
abstract: Adenoid cystic carcinoma (ACC) of the trachea is rare, it represents 1% of all respiratory tract cancers. It's generally considered as a slow-growing, with pronlonged clinical course. Most patients present with dyspnea, and the symptoms often mimic those of asthma or chronic bronchitis Surgical resection is the mainstay of treatment often combined to radiotherapy because of close surgical margins. When surgery isn't possible, most tumors respond to radiotherapy alone wich often results in long periods of remission We report two cases of primary ACC of trachea: a 49 year old male presented a distal unresectable tracheal ACC treated with chemo-radiotherapy who developed a recurrence and died 7 years after the diagnosis. And a 50 years old female with a proximal tracheal tumor treated by surgical resection and end- to- end anastomosis followed by adjuvant radiotherapy. At 10 months follow-up, our patient shows no evidence of disease with negative histological findings.
authors: Department of Radiation Oncology, Mohamed V Military Teaching Hospital, University Mohammed V Souissi, Rabat, Morocco.
authors: Mohammed
authors: M
authors: El Marjany
authors: Department of Thoracic Surgery, Mohamed V Military Teaching Hospital, University Mohamed V Souissi, Rabat, Morocco.
authors: Adil
authors: A
authors: Arsalane
authors: Department of Radiation Oncology, Mohamed V Military Teaching Hospital, University Mohammed V Souissi, Rabat, Morocco.
authors: Hassan
authors: H
authors: Sifat
authors: Department of Radiation Oncology, Mohamed V Military Teaching Hospital, University Mohammed V Souissi, Rabat, Morocco.
authors: Khalid
authors: K
authors: Andaloussi
authors: Department of Histopathology, Mohamed V Military Teaching Hospital, University Mohamed V Souissi, Rabat, Morocco.
authors: Mohamed
authors: M
authors: Oukabli
authors: Department of Radiation Oncology, Mohamed V Military Teaching Hospital, University Mohammed V Souissi, Rabat, Morocco.
authors: Khalid
authors: K
authors: Hadadi
authors: Department of Thoracic Surgery, Mohamed V Military Teaching Hospital, University Mohamed V Souissi, Rabat, Morocco.
authors: El Hassan
authors: el H
authors: Kabiri
authors: Department of Radiation Oncology, Mohamed V Military Teaching Hospital, University Mohammed V Souissi, Rabat, Morocco.
authors: Hamid
authors: H
authors: Mansouri
mesh_terms: D003528:Carcinoma, Adenoid Cystic / Q000473:pathology* / Q000628:therapy; D004417:Dyspnea / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018714:Radiotherapy, Adjuvant / Q000379:methods; D014134:Tracheal Neoplasms / Q000473:pathology* / Q000628:therapy
keywords: Adenoid cystic carcinoma; radiotherapy; trachea; tracheal resection