title: α-Transducin and α-gustducin immunoreactive cells in the stomach of common sole (Solea solea) fed with mussel meal.
abstract: Vertebrates perceive a variety of exogenous substances using two main chemosensory systems, taste and olfaction. The taste perception occurs through the interaction of taste receptors associated with specific G protein subunits such as α-transducin (Gαtran) and α-gustducin (Gαgust). Aquatic vertebrates are also provided with a chemosensory system consisting of solitary chemosensory cells distributed to the oropharynx and skin. In this study, we identified Gαtran and Gαgust-immunoreactive cells intermingled with non-labeled epithelial cells in the gastric mucosa of the common sole. A long-term diet with increasing concentrations of mussel meal in the protein component of a conventional fish meal-based diet induced a dose-dependent increase in the gastric epithelial area and density of Gαtran and Gαgust immunoreactive cells. These findings suggest that taste-related molecules are regulated by changes in diet formulation in common sole aquaculture.
authors: Department of Veterinary Medical Science, University of Bologna, Via Tolara di Sopra, 50, 40064, Ozzano dell'emilia, Bologna, Italy, m.mazzoni@unibo.it.
authors: Maurizio
authors: M
authors: Mazzoni
authors: Alessio
authors: A
authors: Bonaldo
authors: Pier Paolo
authors: PP
authors: Gatta
authors: Claudia
authors: C
authors: Vallorani
authors: Rocco
authors: R
authors: Latorre
authors: Marco
authors: M
authors: Canova
authors: Paolo
authors: P
authors: Clavenzani
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000818:Animals; D017756:Aquaculture / Q000379:methods*; D049872:Bivalvia / Q000737:chemistry; D005412:Flatfishes / Q000502:physiology*; D005526:Food, Formulated; D005753:Gastric Mucosa / Q000166:cytology* / Q000378:metabolism; D007150:Immunohistochemistry / Q000662:veterinary; D013649:Taste / Q000502:physiology*; D015293:Transducin / Q000378:metabolism*
chemical_list: C075192:gustducin; D015293:Transducin