title: Anthracosis mimicking mediastinal lymph node metastases with 18F-FCholine in high-risk prostate cancer.
abstract: A 62-year-old patient with prostate adenocarcinoma underwent PET with radiolabeled choline (18F-Fcholine) for pretreatment staging of a high-risk prostate cancer. Images showed a significant mediastinal lymph node uptake of 18F-Fcholine. Owing to the rarity of spread to supradiaphragmatic lymph nodes, a surgical removal was performed, revealing anthracosis and no malignant cells. Even if its specificity seems better than 18F-FDG, false positives have been reported and other pathologies could mimic lymph node metastases. Consequently, histology should be performed so that the appropriate treatment can be initiated.
authors: From the *Service de Médecine Nucléaire, Hôpital Pellegrin, CHU Bordeaux, Bordeaux; †INCIA, UMR CNRS 5287, université Bordeaux Segalen, Bordeaux; ‡Service d'Urologie, Hôpital Pellegrin, CHU Bordeaux, Bordeaux; and §Service d'anatomopathologie, Hôpital du Haut-Lévêque, CHU Bordeaux, Bordeaux, France.
authors: Jean-Baptiste
authors: JB
authors: Pinaquy
authors: Philippe
authors: P
authors: Fernandez
authors: Gilles
authors: G
authors: Pasticier
authors: Marie
authors: M
authors: Parrens
authors: Henri
authors: H
authors: De Clermont
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D055008:Anthracosis / Q000000981:diagnostic imaging*; D002794:Choline / Q000031:analogs & derivatives*; D005189:False Positive Reactions; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008297:Male; D008482:Mediastinum / Q000000981:diagnostic imaging; D008875:Middle Aged; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D019275:Radiopharmaceuticals
chemical_list: D019275:Radiopharmaceuticals; C514960:fluorocholine; D002794:Choline