title: Copper-mediated synthesis of pyrazolo[1,5-a]pyridines through oxidative linkage of C-C/N-N bonds.
abstract: Copper-mediated synthesis of pyrazolo[1,5-a]pyridine-3-carboxylates through oxidative linkage of C-C and N-N bonds under mild reaction conditions is described. This protocol is applicable to a variety of pyridyl esters as well as various benzonitriles including nicotinonitrile, isonicotinonitrile and thiophene-2-carbonitrile. Better yields were observed with electron withdrawing substituted benzonitriles.
authors: Academy of Scientific & Innovative Research, CSIR-Central Salt & Marine Chemicals Research Institute, G.B. Marg, Bhavnagar-364 002, Gujarat, India. adimurthy@csmcri.org.
authors: Darapaneni Chandra
authors: DC
authors: Mohan
authors: Chitrakar
authors: C
authors: Ravi
authors: Sadu Nageswara
authors: SN
authors: Rao
authors: Subbarayappa
authors: S
authors: Adimurthy