title: Lactococcus lactis Catherter-Related Bloodstream Infection in an Infant: Case Report.
abstract: Lactococcus lactis is a gram-positive coccus that is nonpathogenic in humans. Herein, we present the case of a 1-year-old boy with Down syndrome and Hirschprung's disease (HD) who developed a catheter-related bloodstream infection with L. lactis after gastrointestinal surgery. The patient had been hospitalized in the pediatric surgery unit from birth because of HD, and had undergone the Duhamel-Martin procedure which caused recurrent diarrhea episodes and feeding intolerance. On the infant's 430th day of life, he had an episode of gastroenteritis and feeding intolerance. Because of clinical suspiction of sepsis, blood cultures were taken both from the central venous catheter and peripheral vein, and evidence of a growing microorganism was detected in 2 different central venous catheter blood cultures taken 2 days apart. The colonies were then identified by both the Vitek 2 and Vitek MS systems (bioMérieux, Marseille, France) as L. lactis spp. lactis. The central venous catheter could not be removed because of the absence of a peripheral venous line, and the patient was subsequently successfully treated with vancomycin. Therefore, although Lactococcus species is generally thought to be nonpathogenic, it should still be kept in mind as a potential pathogen in infants.
authors: Department of Pediatrics and Division of Pediatric Infectious Diseases, Medical School, Marmara University.
authors: Ayşe
authors: A
authors: Karaaslan
authors: Ahmet
authors: A
authors: Soysal
authors: Abdurrahman
authors: A
authors: Sarmış
authors: Eda Kepenekli
authors: EK
authors: Kadayifci
authors: Kıvılcım
authors: K
authors: Cerit
authors: Serkan
authors: S
authors: Atıcı
authors: Güner
authors: G
authors: Söyletir
authors: Mustafa
authors: M
authors: Bakır
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D055499:Catheter-Related Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D004314:Down Syndrome / Q000150:complications; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D006627:Hirschsprung Disease / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D013294:Lactococcus lactis / Q000302:isolation & purification*; D008297:Male; D018805:Sepsis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D016896:Treatment Outcome; D014421:Turkey; D014640:Vancomycin / Q000008:administration & dosage
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin