title: Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Brønsted acids.
abstract: The effective and efficient removal of the BF2 moiety from F-BODIPY derivatives has been achieved using two common Brønsted acids; treatment with trifluoroacetic acid (TFA) or methanolic hydrogen chloride (HCl) followed by work-up with Ambersep(®) 900 resin (hydroxide form) effects this conversion in near-quantitative yields. Compared to existing methods, these conditions are relatively mild and operationally simple, requiring only reaction at room temperature for six hours (TFA) or overnight (HCl).
authors: School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
authors: Mingfeng
authors: M
authors: Yu
authors: School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
authors: Joseph K-H
authors: JK
authors: Wong
authors: School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
authors: Cyril
authors: C
authors: Tang
authors: Crystal Structure Analysis Facility, School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
authors: Peter
authors: P
authors: Turner
authors: School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
authors: Matthew H
authors: MH
authors: Todd
authors: School of Chemistry, The University of Sydney, Sydney, New South Wales 2006, Australia.
authors: Peter J
authors: PJ
authors: Rutledge
keywords: Brønsted acids; F-BODIPYs; click chemistry; deboration; dipyrrins