title: A review of detrusor overactivity and the overactive bladder after radical prostate cancer treatment.
abstract: There are various forms of treatment for prostate cancer. In addition to oncologic outcomes, physicians, and increasingly patients, are focusing on functional and adverse outcomes. Symptoms of overactive bladder (OAB), including urinary frequency, urgency and incontinence, can occur regardless of treatment modality. This article examines the prevalence, pathophysiology and options for treating OAB after radical prostate cancer treatment. OAB seems to be more common and severe after radiation therapy than after surgical therapy and even persisted longer with complications, suggesting an advantage for surgery over radiotherapy. Because OAB that occurs after radical prostate surgery or radiotherapy can be difficult to treat, it is important that patients are made aware of the potential development of OAB during counselling before decisions regarding treatment choice are made. To ensure a successful outcome of both treatments, it is imperative that clinicians and non-specialists enquire about and document pretreatment urinary symptoms and carefully evaluate post-treatment symptoms.
authors: Department of Urology, Cambridge University Hospitals NHS Trust, Cambridge, UK.
authors: Nikesh
authors: N
authors: Thiruchelvam
authors: Faculty of Medicine, Hospital S. Joao, Porto, Portugal.
authors: Francesco
authors: F
authors: Cruz
authors: Faculty of Health and Human Sciences, University of Hertfordshire and the Prostate Centre, London, UK.
authors: Mike
authors: M
authors: Kirby
authors: Department of Urology, La Sapienza, University of Rome, Rome, Italy.
authors: Andrea
authors: A
authors: Tubaro
authors: Sheffield Teaching Hospital, NHS Foundation Trust, Sheffield, UK.
authors: Christopher R
authors: CR
authors: Chapple
authors: Department of Urology, Eberhard-Karls-University, Hoppe-Seyler Strasse 3, 72076, Tuebingen, Germany.|Department of Urology, Lübeck, Schleswig-Holstein, Ratzeburger Allee 160, 23538, Lübeck, Germany.|Dept of Urology and Andrology, SALK Clinic/Paracelsus Medical University, Salzburg, Austria.
authors: Karl-Dietrich
authors: KD
authors: Sievert
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D011467:Prostate / Q000601:surgery; D011468:Prostatectomy / Q000009:adverse effects*; D011471:Prostatic Neoplasms / Q000628:therapy*; D053201:Urinary Bladder, Overactive
keywords: brachytherapy; overactive bladder (OAB); prostate cancer; prostatectomy; radiotherapy