title: Clinical inquiry: what is the best beta-blocker for systolic heart failure?
abstract: Three beta-blockers--carvedilol, metoprolol succinate, and bisoprolol--reduce mortality equally (by about 30% over one year) in patients with Class III or IV systolic heart failure. Insufficient evidence exists comparing equipotent doses of these medications head-to-head to recommend any one over the others.
authors: Mountain Area Health Education Center, Asheville, NC, USA.
authors: Stephen
authors: S
authors: Hulkower
authors: Mountain Area Health Education Center, Asheville, NC, USA.
authors: Benjamin A
authors: BA
authors: Aiken
authors: Mountain Area Health Education Center, Asheville, NC, USA.
authors: Sue
authors: S
authors: Stigleman
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D054143:Heart Failure, Systolic / Q000188:drug therapy*; D006801:Humans; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists