title: Stable and efficient loading of silver nanoparticles in spherical polyelectrolyte brushes and the antibacterial effects.
abstract: A more efficient and convenient strategy was demonstrated to immobilize silver nanoparticles (NPs) with a crystalline structure into the spherical polyelectrolyte brushes (SPB) as an antibacterial material. The SPB used for surface coating (Ag immobilized PVK-PAA SPB) consists of a poly(N-vinylcarbazole) (PVK) core and poly(acrylic acid) (PAA) chain layers which are anchored onto the surface of PVK core at one end. Well-dispersed silver nanoparticles (diameter∼3.5 nm) then formed and were electrostatically confined in the brush layer. Ag content is controlled by a repeated loading process. Thin film coatings were then constructed by layer-by-layer depositions of positive charged poly(diallyldimethylammonium chloride) (PDDA) and SPB. The multilayer composites display excellent stability as well as antibacterial performance but not for simple PVK-PAA coated surface. The results show that almost complete bacteria growth including both dispersed bacterial cells and biofilms was inhibited over a period of 24 h. This approach opens a novel strategy for stable and efficient immobilization of Ag NPs in fabrication of antibacterial materials.
authors: State-Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China.
authors: Xiaochi
authors: X
authors: Liu
authors: State-Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China; Zhejiang Provincial Key Laboratory for Chemical & Biochemical Processing Technology of Farm Products, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, 318 Liuhe Road, Hangzhou 310023, China. Electronic address: yshxu@ecust.edu.cn.
authors: Yisheng
authors: Y
authors: Xu
authors: State-Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China.
authors: Xiaohan
authors: X
authors: Wang
authors: Harbin Institute of Technology Shenzhen Graduate School, Shenzhen, Guangdong 518055, China; Shenzhen Key Laboratory of Water Resource Utilization and Environmental Pollution Control, Shenzhen, Guangdong 518055, China. Electronic address: mfshao@hitsz.edu.cn.
authors: Mingfei
authors: M
authors: Shao
authors: State-Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China.
authors: Jun
authors: J
authors: Xu
authors: State-Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China.
authors: Jie
authors: J
authors: Wang
authors: State-Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China.
authors: Li
authors: L
authors: Li
authors: State-Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China.
authors: Rui
authors: R
authors: Zhang
authors: State-Key Laboratory of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China; Key Laboratory of Materials-Oriented Chemical Engineering of Xinjiang Uygur Autonomous Region, Shihezi University, Xinjiang 832000, China. Electronic address: guoxuhong@ecust.edu.cn.
authors: Xuhong
authors: X
authors: Guo
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004573:Electrolytes / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008826:Microbial Sensitivity Tests; D010316:Particle Size; D011145:Polyvinyls / Q000737:chemistry; D012834:Silver / Q000737:chemistry / Q000494:pharmacology*; D013056:Spectrophotometry, Ultraviolet; D013818:Thermogravimetry
chemical_list: D000180:Acrylic Resins; D000900:Anti-Bacterial Agents; D004573:Electrolytes; D011145:Polyvinyls; C035125:poly-N-vinylcarbazole; D012834:Silver; C006903:carbopol 940
keywords: Antibacterial; Poly(N-vinylcarbazole); Silver nanoparticles; Spherical polyelectrolyte brush