title: A review of compression, ventilation, defibrillation, drug treatment, and targeted temperature management in cardiopulmonary resuscitation.
abstract: OBJECTIVE
  Important studies of cardiopulmonary resuscitation (CPR) techniques influence the development of new guidelines. We systematically reviewed the efficacy of some important studies of CPR.
  
  
  METHODS
  The data analyzed in this review are mainly from articles included in PubMed and EMBASE, published from 1964 to 2014.
  
  
  METHODS
  Original articles and critical reviews about CPR techniques were selected for review.
  
  
  RESULTS
  The survival rate after out-of-hospital cardiac arrest (OHCA) is improving. This improvement is associated with the performance of uninterrupted chest compressions and simple airway management procedures during bystander CPR. Real-time feedback devices can be used to improve the quality of CPR. The recommended dose, timing, and indications for adrenaline (epinephrine) use may change. The appropriate target temperature for targeted temperature management is still unclear.
  
  
  CONCLUSIONS
  New studies over the past 5 years have evaluated various aspects of CPR in OHCA. Some of these studies were high-quality randomized controlled trials, which may help to improve the scientific understanding of resuscitation techniques and result in changes to CPR guidelines.
authors: Jian
authors: J
authors: Pan
authors: Jian-Yong
authors: JY
authors: Zhu
authors: Ho Sen
authors: HS
authors: Kee
authors: Qing
authors: Q
authors: Zhang
authors: Department of Emergency Medicine, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China.
authors: Yuan-Qiang
authors: YQ
authors: Lu
mesh_terms: D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D004554:Electric Countershock / Q000379:methods*; D004837:Epinephrine / Q000627:therapeutic use; D006801:Humans; D058687:Out-of-Hospital Cardiac Arrest / Q000517:prevention & control*; D013696:Temperature
chemical_list: D004837:Epinephrine