title: [A case report: an EML4-ALK positive lung adenocarcinoma diagnosed  with lymphoma previously].
abstract: In recent years, with the deepening of the research of molecular biology, targeted therapy has become one of the trend of lung cancer treatment. The individualized treatment of lung cancer is attached great importance at present. Echinoderm microtubule associated protein like 4 anaplastic lymphoma kinase (EML4-ALK) as a new biological marker is a hot topic in the field of lung cancer treatment. Meanwhile, with the improvement of anticancer treatment and survival, the incidence of multiple primary carcinomas (MPC) has become increasingly. But the report that malignant lymphoma complicated with lung adenocarcinoma harboring EML4-ALK fusion gene in one individual is rare. Here, we report an EML4-ALK positive non-small cell lung cancer (NSCLC) in a patient previously diagnosed with T cell lymphoma and review literature on metachronous lung cancer complicating with lymphoma.
authors: Department of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
authors: Li
authors: L
authors: Liu
authors: Department of Respiratory Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.
authors: Wei
authors: W
authors: Heng
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000201:enzymology / Q000209:etiology / Q000235:genetics; D000077192:Adenocarcinoma of Lung; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000201:enzymology / Q000209:etiology / Q000235:genetics; D008223:Lymphoma / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015514:Oncogene Proteins, Fusion / Q000235:genetics*
chemical_list: C522504:EML4-ALK fusion protein, human; D015514:Oncogene Proteins, Fusion