title: [Thrombotic vasculopathy probably associated with cocaine contaminated with levamisole: report of 2 cases].
abstract: The vasculities are complex diseases. Their cutaneous manifestations are very important and often mirror several pathologies. Cocaine use has been related to both, vasculitis and thrombotic vasculopathy and pseudovasculitis. A new syndrome has been described in association with its adulteration with levamisole. It can be very serious, leading patients to death. This is relevant as levamisole-adultered cocaine seems to be increasingly offered to consumers. Our goal is to report the first two cases in Mexico, which faces an important raise in cocaine use, emphasizing that a high suspicion based on certain characteristics allows for early recognition and adequate treatment.
authors: División de Dermatología, Hospital General "Dr. Manuel Gea González", Secretaría de Salud, Distrito Federal, México. abrilbrug@hotmail.com.
authors: María Abril
authors: MA
authors: Martínez-Velasco
authors: Luis Felipe
authors: LF
authors: Flores-Suárez
authors: Sonia
authors: S
authors: Toussaint-Caire
authors: Angélica
authors: A
authors: Rodríguez-Carreón
authors: Marisol
authors: M
authors: Díaz-Lozano
authors: Karen
authors: K
authors: Sánchez-Armendáriz
mesh_terms: D000328:Adult; D002196:Capillaries / Q000187:drug effects; D003042:Cocaine / Q000737:chemistry*; D004340:Drug Contamination; D006801:Humans; D013287:Illicit Drugs / Q000737:chemistry* / Q000633:toxicity*; D007978:Levamisole / Q000633:toxicity*; D008297:Male; D008800:Mexico; D012867:Skin / Q000098:blood supply; D013927:Thrombosis / Q000139:chemically induced* / Q000175:diagnosis; D014657:Vasculitis / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D013287:Illicit Drugs; D007978:Levamisole; D003042:Cocaine
keywords: Cocaine; Levamisole; Neutropenia; Thrombotic vasculopathy; Vasculitis