title: Biologic enhancement of cartilage repair: the role of platelet-rich plasma and other commercially available growth factors.
abstract: In part, people's quality of life depends on the "health" of their cartilage because its damage or deterioration causes pain that limits mobility and reduces autonomy. Predisposing genetic factors and modern-life environmental factors, such as diet, excessive physical exercise, or the absence of any physical exercise, in addition to injuries that can occur, all contribute to the onset and development of chronic degenerative diseases such as osteoarthritis. Regenerative medicine focuses on the repair, replacement, or regeneration of cells, tissues, or organs to restore impaired function from any cause, including congenital defects, disease, and trauma.
authors: Division of Medicine and Regenerative Surgery, Garcia Cugat Foundation and CEU Cardenal Herrera University, Valencia, Spain; Mutualidad de Futbolistas, Royal Spanish Football Federation, Barcelona, Spain; Department of Orthopaedic Surgery, Sports Medicine and Trauma, Hospital Quiron Barcelona, Barcelona, Spain. Electronic address: info@fundaciongarciacugat.org.
authors: Ramon
authors: R
authors: Cugat
authors: Division of Medicine and Regenerative Surgery, Garcia Cugat Foundation and CEU Cardenal Herrera University, Valencia, Spain; Department of Orthopaedic Surgery, Sports Medicine and Trauma, Hospital Quiron Barcelona, Barcelona, Spain.
authors: Xavier
authors: X
authors: Cuscó
authors: Division of Medicine and Regenerative Surgery, Garcia Cugat Foundation and CEU Cardenal Herrera University, Valencia, Spain; Department of Orthopaedic Surgery, Sports Medicine and Trauma, Hospital Quiron Barcelona, Barcelona, Spain.
authors: Roberto
authors: R
authors: Seijas
authors: Division of Medicine and Regenerative Surgery, Garcia Cugat Foundation and CEU Cardenal Herrera University, Valencia, Spain; Mutualidad de Futbolistas, Royal Spanish Football Federation, Barcelona, Spain; Department of Orthopaedic Surgery, Sports Medicine and Trauma, Hospital Quiron Barcelona, Barcelona, Spain.
authors: Pedro
authors: P
authors: Álvarez
authors: Division of Medicine and Regenerative Surgery, Garcia Cugat Foundation and CEU Cardenal Herrera University, Valencia, Spain; Mutualidad de Futbolistas, Royal Spanish Football Federation, Barcelona, Spain; Department of Orthopaedic Surgery, Sports Medicine and Trauma, Hospital Quiron Barcelona, Barcelona, Spain.
authors: Gilbert
authors: G
authors: Steinbacher
authors: Division of Medicine and Regenerative Surgery, Garcia Cugat Foundation and CEU Cardenal Herrera University, Valencia, Spain; Department of Orthopaedic Surgery, Sports Medicine and Trauma, Hospital Quiron Barcelona, Barcelona, Spain.
authors: Oscar
authors: O
authors: Ares
authors: Division of Medicine and Regenerative Surgery, Garcia Cugat Foundation and CEU Cardenal Herrera University, Valencia, Spain; Department of Orthopaedic Surgery, Sports Medicine and Trauma, Hospital Quiron Barcelona, Barcelona, Spain; Department of Regenerative Medicine, WGB Regenerative Medicine Hospital Quiron Barcelona, Barcelona, Spain.
authors: Ana
authors: A
authors: Wang-Saegusa
authors: Division of Medicine and Regenerative Surgery, Garcia Cugat Foundation and CEU Cardenal Herrera University, Valencia, Spain; Department of Orthopaedic Surgery, Sports Medicine and Trauma, Hospital Quiron Barcelona, Barcelona, Spain; Department of Regenerative Medicine, WGB Regenerative Medicine Hospital Quiron Barcelona, Barcelona, Spain.
authors: Montserrat
authors: M
authors: García-Balletbó
mesh_terms: D002358:Cartilage, Articular / Q000293:injuries / Q000502:physiology* / Q000503:physiopathology; D006801:Humans; D051457:Hyaline Cartilage / Q000502:physiology; D036341:Intercellular Signaling Peptides and Proteins / Q000502:physiology*; D010003:Osteoarthritis / Q000503:physiopathology* / Q000628:therapy; D053657:Platelet-Rich Plasma / Q000502:physiology*; D012038:Regeneration
chemical_list: D036341:Intercellular Signaling Peptides and Proteins