title: Use of ruxolitinib to successfully treat chronic mucocutaneous candidiasis caused by gain-of-function signal transducer and activator of transcription 1 (STAT1) mutation.
authors: Dermatology, St James's Hospital, Dublin, Ireland.
authors: Eleanor
authors: E
authors: Higgins
authors: Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom.
authors: Tariq
authors: T
authors: Al Shehri
authors: National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland.
authors: Maeve A
authors: MA
authors: McAleer
authors: Immunology, St James's Hospital, Dublin, Ireland.
authors: Niall
authors: N
authors: Conlon
authors: Immunology, St James's Hospital, Dublin, Ireland.
authors: Conleth
authors: C
authors: Feighery
authors: Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom. Electronic address: irvinea@tcd.ie.
authors: Desa
authors: D
authors: Lilic
authors: Dermatology, St James's Hospital, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Department of Clinical Medicine, Trinity College Dublin, Dublin, Ireland. Electronic address: desa.lilic@newcastle.ac.uk.
authors: Alan D
authors: AD
authors: Irvine
mesh_terms: D002178:Candidiasis, Chronic Mucocutaneous / Q000188:drug therapy* / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D009154:Mutation; D009570:Nitriles; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011720:Pyrazoles / Q000627:therapeutic use*; D011743:Pyrimidines; D050794:STAT1 Transcription Factor / Q000235:genetics*; D016896:Treatment Outcome
chemical_list: D009570:Nitriles; D047428:Protein Kinase Inhibitors; D011720:Pyrazoles; D011743:Pyrimidines; D050794:STAT1 Transcription Factor; C540383:ruxolitinib