title: Primary plasma cell leukemia presenting as a thoracic mass.
abstract: Primary Plasma cell leukaemia (pPCL) is a rare plasma cell (PC) malignancy. The strict criteria for the diagnosis is an absolute PC number greater 2 × 10(9)/L or a plasmocytosis accounting for > 20% of the differential white cell count that does not arise from a pre-existing multiple myeloma. pPCL was associated with aggressive clinic-biological features. Primary Plasma cell leukaemia is more characterised by an extra medullar involvement such as hepatomegaly, splenomegaly, lymphadenopathy, lepto-meningeal infiltration or extramedullary plasmocytomas. The prognosis of pPCL is very poor. We report the case of a fifty eight year-old man directed to the haematology department for diagnosis of pPCL revealed by a thoracic plasmocytomas mimicking a thoracic neoplasm. The patient received chemotherapy including a classic treatment for multiple myeloma but developed a pulmonary embolism. This case illustrates an uncommon presentation of pPCL the difficulty treating by multiple myeloma chemotherapy.
authors: Hematology Department, CHU IBN Rochd, Faculty of Medicine and Pharmacy, Universite Ain Chock, Casablanca Morocco.
authors: Marielle
authors: M
authors: Igala
authors: Pneumology Department, CHU IBN Rochd, Faculty of Medicine and Pharmacy, Universite Ain Chock, Casablanca Morocco.
authors: Regis Gothar
authors: RG
authors: Bopaka
authors: Pneumology Department, CHU IBN Rochd, Faculty of Medicine and Pharmacy, Universite Ain Chock, Casablanca Morocco.
authors: Wiam
authors: W
authors: Khtabi
authors: Hematology Department, CHU IBN Rochd, Faculty of Medicine and Pharmacy, Universite Ain Chock, Casablanca Morocco.
authors: Said
authors: S
authors: Benchekroun
authors: Hematology Department, CHU IBN Rochd, Faculty of Medicine and Pharmacy, Universite Ain Chock, Casablanca Morocco.
authors: Asma
authors: A
authors: Quessar
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007952:Leukemia, Plasma Cell / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis*; D011379:Prognosis; D011655:Pulmonary Embolism / Q000209:etiology*
chemical_list: D000970:Antineoplastic Agents
keywords: Plasma cells leukaemia; pulmonary embolism; thoracic mass