title: Effect of virtual reality-based balance training in multiple sclerosis.
abstract: OBJECTIVE
  Balance and mobility impairments are common life-altering complications in patients with multiple sclerosis (MS). In this study, we aimed to investigate the efficacy of a short-term virtual reality (VR)-based balance training program on the balance ability of patients with MS.
  
  
  METHODS
  In this randomized controlled trial, 30 patients with relapsing-remitting or secondary-progressive MS were randomly assigned to an intervention or a control group. The intervention group performed a balance training program [postural stability training program (PST)] using the Biodex Balance System SD. Subjects in both groups were assessed using the manual muscle test (MMT), timed 'up and go' (TUG) test, the modified Ashworth scale, the Romberg test, the Berg balance scale (BBS), and the fall risk and postural stability tests, at baseline and after 12  weeks.
  
  
  RESULTS
  The TUG, fall risk index (FRi), and overall stability index (OSI) were significantly improved in the intervention group after 24 sessions of balance training. The changes in TUG, Fri, and OSi indices in the intervention group were significantly higher than the control group.
  
  
  CONCLUSIONS
  According to the fall risk and postural stability tests results, the VR-based balance training program could improve the balance ability of the patients with MS.
authors: Bina
authors: B
authors: Eftekharsadat
authors: Arash
authors: A
authors: Babaei-Ghazani
authors: Mehran
authors: M
authors: Mohammadzadeh
authors: Mahnaz
authors: M
authors: Talebi
authors: Fariba
authors: F
authors: Eslamian
authors: Elnaz
authors: E
authors: Azari
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D020528:Multiple Sclerosis, Chronic Progressive / Q000503:physiopathology / Q000534:rehabilitation*; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000503:physiopathology / Q000534:rehabilitation*; D026741:Physical Therapy Modalities; D004856:Postural Balance; D012306:Risk; D012720:Severity of Illness Index; D016037:Single-Blind Method; D016896:Treatment Outcome; D014584:User-Computer Interface
keywords: Balance training,; Multiple sclerosis,; Postural stability