title: Digital image analysis of blood cells.
abstract: Rapid and accurate counts of red blood cells (RBCs), nucleated RBCs, platelets, and white blood cells (WBCs) (total and differential WBCs) are important requirements for a hematology laboratory. The detection of abnormal blood cell populations and the recognition of pathologic distributions of leukocytes are also of clinical importance. Manual microscopy counts are still required when a sample is flagged by the hematology analyzer and are still the reference method for WBC differential counts. Automated microscopy analyzers can provide accurate WBC differential counts, which may replace manual microscopy, but should not replace the eye of the cytologist.
authors: AP-HP, Robert Debré, 48 Boulevard Sérurier, Paris F-75019, France; Sorbonne Paris Cité, Paris 7, Paris F-75010, France; Inserm U1149, Bichat-Claude Bernard, CRI, Paris F-75018, France; Laboratoire d'excellence des globules rouges, GR-Ex, Paris France. Electronic address: lydie.dacosta@rdb.aphp.fr.
authors: Lydie
authors: L
authors: Da Costa
mesh_terms: D001331:Automation; D001772:Blood Cell Count / Q000266:history / Q000295:instrumentation / Q000379:methods*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation / Q000379:methods
keywords: ANC; Automated blood cells analyzers; CellaVision; Differentials; Digital image