title: Target-specific 3D DNA gatekeepers for biomimetic nanopores.
abstract: 3D cross-linked DNA superstructures switch off the ionic flux through solid-state nanopores with extremely high ON-OFF ratios of 10(3) -10(5) . This gating mechanism can be generally applicable in a wide range of nanopores with opening diameters up to 650 nm. The 3D bio-supramolecular gatekeepers outperform previous low-dimensional or simple-structured DNA functional components.
authors: Key Laboratory for Large-Format Battery Materials and Systems, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan, 430074, P.R. China; Laboratory of Bio-Inspired Smart Interface Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P.R. China.
authors: Wei
authors: W
authors: Guo
authors: Fan
authors: F
authors: Hong
authors: Nannan
authors: N
authors: Liu
authors: Jiayu
authors: J
authors: Huang
authors: Boya
authors: B
authors: Wang
authors: Ruixue
authors: R
authors: Duan
authors: Xiaoding
authors: X
authors: Lou
authors: Fan
authors: F
authors: Xia
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D008958:Models, Molecular; D058608:Nanopores; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization
chemical_list: D004247:DNA
keywords: DNA; biomimetics; gating; nanopores; responsive materials; smart materials