title: Clinical outcomes for teeth treated with electrospun poly(ε-caprolactone) fiber meshes/mineral trioxide aggregate direct pulp capping.
abstract: BACKGROUND
  Mineral trioxide aggregate (MTA) is a biocompatible material for direct pulp capping. This study was designed to compare the clinical outcomes of pulp-exposed teeth treated with either poly(ε-caprolactone) fiber mesh (PCL-FM) as a barrier for MTA (so-called PCL-FM/MTA) or MTA direct pulp capping.
  
  
  METHODS
  Sixty human vital teeth were evenly divided into 4 groups (n = 15 in each group). Teeth in groups 1 and 3 had pulp exposure <1 mm in diameter, whereas teeth in groups 2 and 4 had pulp exposure of 1-1.5 mm in diameter. Teeth in groups 1 and 2 were treated with PCL-FM/MTA direct pulp capping, and those in groups 3 and 4 were treated with MTA direct pulp capping.
  
  
  RESULTS
  Teeth treated with PCL-FM/MTA direct pulp capping needed a significantly shorter mean duration for dentin bridge formation than teeth treated with MTA direct pulp capping. Moreover, teeth with pulp exposure <1.0 mm in diameter needed a significantly shorter mean duration for dentin bridge formation than teeth with pulp exposure of 1-1.5 mm in diameter after either PCL-FM/MTA or MTA direct pulp capping treatment. In addition, teeth treated with PCL-FM/MTA direct pulp capping formed an approximately 3-fold thicker dentin bridge than teeth treated with MTA direct pulp capping 8 weeks or 3 months later. Furthermore, none of the teeth treated with PCL-FM/MTA direct pulp capping showed tooth discoloration after treatment for 3 months.
  
  
  CONCLUSIONS
  PCL-FM/MTA is a better combination material than MTA alone for direct pulp capping of human permanent teeth.
authors: Department of Dentistry, Taipei City Hospital, Renai Branch, Taipei, Taiwan.
authors: Li-Wan
authors: LW
authors: Lee
authors: Department of Neurosurgery, Taipei City Hospital, Renai Branch, Taipei, Taiwan; Institute of Traditional Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
authors: Sheng-Huang
authors: SH
authors: Hsiao
authors: School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan; Division of Endodontics, Department of Dentistry, Taipei Medical University Hospital, Taipei, Taiwan.
authors: Wei-Chiang
authors: WC
authors: Hung
authors: School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan; Division of Oral Pathology, Department of Dentistry, Taipei Medical University Hospital, Taipei, Taiwan.
authors: Yun-Ho
authors: YH
authors: Lin
authors: Institute of Polymer Science and Engineering, National Taiwan University, Taipei, Taiwan.
authors: Po-Yu
authors: PY
authors: Chen
authors: Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan; Department of Dentistry, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan. Electronic address: cpchiang@ntu.edu.tw.
authors: Chun-Pin
authors: CP
authors: Chiang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D017607:Aluminum Compounds; D001672:Biocompatible Materials; D017610:Calcium Compounds; D002648:Child; D003785:Dental Pulp Capping / Q000379:methods*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008422:Materials Testing; D008875:Middle Aged; D010087:Oxides; D011091:Polyesters; D057872:Pulp Capping and Pulpectomy Agents; D017640:Silicates; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D017607:Aluminum Compounds; D001672:Biocompatible Materials; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D011091:Polyesters; D057872:Pulp Capping and Pulpectomy Agents; D017640:Silicates; C086631:mineral trioxide aggregate; C016240:polycaprolactone
keywords: Clinical outcome; dentin bridge; direct pulp capping; mineral trioxide aggregate; poly(ε-caprolactone) fiber meshes; pulp-exposed permanent teeth