title: Spectral-domain optical coherence tomography measurements of central foveal thickness before and after cataract surgery in children.
abstract: OBJECTIVE
  To compare macular thickness before and after cataract surgery and intraocular lens (IOL) implantation in pediatric eyes.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  University Eye Clinic, San Giuseppe Hospital, University of Milan, Milan, Italy.
  
  
  METHODS
  The study analyzed spectral-domain optical coherence tomography (SD-OCT) images of the macula in pediatric eyes in which cataract surgery had been performed and that were examined preoperatively and 1, 3, 6, 9, and 12 months postoperatively.
  
  
  RESULTS
  The mean age of the 11 patients (11 eyes) was 5.8 years ± 2.2 (SD) (range 3 to 14 years). The mean macular thickness at 1 month and 3 months was significantly higher than at baseline (273.7 ± 26.8 μm and 266.0 ± 22.8 μm, respectively, versus 244.8 ± 19.5 μm; P < .0001). It reached the baseline value after 3 months and remained stable over the 12-month follow-up. The mean thicknesses at 6, 9, and 12 months were 249.1 ± 17.6 μm, 245.7 ± 18.5 μm, and 246.2 ± 18.1 μm, respectively (P > .05 versus baseline).
  
  
  CONCLUSIONS
  Spectral-domain OCT was useful in evaluating the macular changes in the eyes of a cohort of pediatric patients 3 years and older. Cystoid macular edema was not observed during the 12-month follow-up.
  
  
  BACKGROUND
  No author has a financial or proprietary interest in any material or method mentioned.
authors: From the University Eye Clinic (Sacchi, Serafino, Alkabes, Gilardoni, Nucci), San Giuseppe Hospital, University of Milan, and IRCCS MultiMedica (Specchia), Milan, and the Department of Molecular and Translational Medicine (Specchia), University of Brescia, Brescia, Italy; Miles Center for Pediatric Ophthalmology (Trivedi), Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors: Matteo
authors: M
authors: Sacchi
authors: From the University Eye Clinic (Sacchi, Serafino, Alkabes, Gilardoni, Nucci), San Giuseppe Hospital, University of Milan, and IRCCS MultiMedica (Specchia), Milan, and the Department of Molecular and Translational Medicine (Specchia), University of Brescia, Brescia, Italy; Miles Center for Pediatric Ophthalmology (Trivedi), Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors: Massimiliano
authors: M
authors: Serafino
authors: From the University Eye Clinic (Sacchi, Serafino, Alkabes, Gilardoni, Nucci), San Giuseppe Hospital, University of Milan, and IRCCS MultiMedica (Specchia), Milan, and the Department of Molecular and Translational Medicine (Specchia), University of Brescia, Brescia, Italy; Miles Center for Pediatric Ophthalmology (Trivedi), Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors: Rupal H
authors: RH
authors: Trivedi
authors: From the University Eye Clinic (Sacchi, Serafino, Alkabes, Gilardoni, Nucci), San Giuseppe Hospital, University of Milan, and IRCCS MultiMedica (Specchia), Milan, and the Department of Molecular and Translational Medicine (Specchia), University of Brescia, Brescia, Italy; Miles Center for Pediatric Ophthalmology (Trivedi), Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors: Claudia
authors: C
authors: Specchia
authors: From the University Eye Clinic (Sacchi, Serafino, Alkabes, Gilardoni, Nucci), San Giuseppe Hospital, University of Milan, and IRCCS MultiMedica (Specchia), Milan, and the Department of Molecular and Translational Medicine (Specchia), University of Brescia, Brescia, Italy; Miles Center for Pediatric Ophthalmology (Trivedi), Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors: Micol
authors: M
authors: Alkabes
authors: From the University Eye Clinic (Sacchi, Serafino, Alkabes, Gilardoni, Nucci), San Giuseppe Hospital, University of Milan, and IRCCS MultiMedica (Specchia), Milan, and the Department of Molecular and Translational Medicine (Specchia), University of Brescia, Brescia, Italy; Miles Center for Pediatric Ophthalmology (Trivedi), Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA.
authors: Francesca
authors: F
authors: Gilardoni
authors: From the University Eye Clinic (Sacchi, Serafino, Alkabes, Gilardoni, Nucci), San Giuseppe Hospital, University of Milan, and IRCCS MultiMedica (Specchia), Milan, and the Department of Molecular and Translational Medicine (Specchia), University of Brescia, Brescia, Italy; Miles Center for Pediatric Ophthalmology (Trivedi), Storm Eye Institute, Department of Ophthalmology, Medical University of South Carolina, Charleston, South Carolina, USA. Electronic address: paolo.nucci@unimi.it.
authors: Paolo
authors: P
authors: Nucci
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D005584:Fovea Centralis / Q000473:pathology*; D006801:Humans; D019654:Lens Implantation, Intraocular; D008269:Macular Edema / Q000175:diagnosis / Q000209:etiology; D008297:Male; D018918:Phacoemulsification; D011184:Postoperative Period; D057234:Preoperative Period; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence