title: Spin trapping: an essential tool for the study of diseases caused by oxidative stress.
abstract: Electron spin resonance (ESR), called also electron paramagnetic resonance (EPR) together with the spin trapping technique, has allowed us to study and understand how free radicals are involved in various pathologies. In this review, the importance of spin trapping technique in the study of diseases such as cancer, diabetes, hypertension and parasitic diseases is discussed. In addition, advances in the use of this technique as therapeutic agents and other interesting applications as the immuno-spin trapping technique are reviewed.
authors: Germán
authors: G
authors: Barriga-González
authors: Claudio
authors: C
authors: Olea-Azar
authors: María C
authors: MC
authors: Zuñiga-López
authors: Christian
authors: C
authors: Folch-Cano
authors: Benjamín
authors: B
authors: Aguilera-Venegas
authors: Williams
authors: W
authors: Porcal
authors: Mercedes
authors: M
authors: González
authors: Universidad Andres Bello, Facultad de Ciencias Exactas, Departamento de Ciencias Quimicas, Avenida Republica 275, 8370146 Santiago, Chile. gbarriga@ciq.uchile.cl.
authors: Hugo
authors: H
authors: Cerecetto
mesh_terms: D000818:Animals; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology; D007896:Leishmaniasis / Q000175:diagnosis / Q000378:metabolism / Q000469:parasitology / Q000473:pathology; D009369:Neoplasms / Q000737:chemistry* / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D019636:Neurodegenerative Diseases / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology; D018384:Oxidative Stress; D013113:Spin Labels / Q000138:chemical synthesis; D019097:Spin Trapping / Q000295:instrumentation / Q000379:methods*; D014352:Trypanosomiasis / Q000175:diagnosis / Q000378:metabolism / Q000469:parasitology / Q000473:pathology
chemical_list: D005609:Free Radicals; D013113:Spin Labels