title: Printing technologies for biomolecule and cell-based applications.
abstract: Biomolecules, such as enzymes, proteins and other biomacromolecules (polynucleotides, polypeptides, polysaccharides and DNA) that are immobilized on solid surfaces are relevant to many areas of science and technology. These functionalized surfaces have applications in biosensors, chromatography, diagnostic immunoassays, cell culturing, DNA microarrays and other analytical techniques. Printing technologies offer opportunities in this context. The main interests in printing biomolecules are in immobilizing them on surfaces for sensors and catalysts or for controlled delivery of protein-based drugs. Recently, there have been significant developments in the use of inkjet printing for dispensing of proteins, biomacromolecules and cells. This review discusses the use of roll-to-roll and inkjet printing technologies in manufacturing of biomolecule and cell-based applications.
authors: Abo Akademi University, Laboratory of Physical Chemistry, Porthaninkatu 3-5, Turku 20500, Finland.
authors: Petri
authors: P
authors: Ihalainen
authors: Abo Akademi University, Laboratory of Physical Chemistry, Porthaninkatu 3-5, Turku 20500, Finland.
authors: Anni
authors: A
authors: Määttänen
authors: Abo Akademi University, Pharmaceutical Sciences Laboratory, Tykistökatu 6 A, Turku 20520, Finland. Electronic address: niklas.sandler@abo.fi.
authors: Niklas
authors: N
authors: Sandler
mesh_terms: D001688:Biological Products / Q000008:administration & dosage*; D060846:Cell Engineering / Q000295:instrumentation; D003199:Computer Systems; D004247:DNA / Q000008:administration & dosage; D016503:Drug Delivery Systems / Q000295:instrumentation*; D004798:Enzymes / Q000008:administration & dosage; D019220:High-Energy Shock Waves; D006801:Humans; D057285:Precision Medicine / Q000295:instrumentation*; D011506:Proteins / Q000008:administration & dosage; D013678:Technology, Pharmaceutical / Q000295:instrumentation*
chemical_list: D001688:Biological Products; D004798:Enzymes; D011506:Proteins; D004247:DNA
keywords: Biomacromolecules; Enzymes; Inkjet; Printing; Proteins; Roll-to-roll printing