title: Evaluation of a simplified version of the Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) comprising 5 joints (RAMRIS5).
abstract: OBJECTIVE
  The objective of this study was to evaluate a simplified version of the Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) reduced to five joints of the hand (RAMRIS5).
  
  
  METHODS
  94 patients with rheumatoid arthritis (62 female; age 59±12 years, range 25-83 years; disease duration 60±90 months (median: 22 months, first quartile: 7 months, third quartile: 66 months) from the REMISSION PLUS study cohort who had complete files on C-reactive protein (CRP) levels and Disease Activity Score of 28 joints (DAS28) and complete MRI of the clinical dominant hand at baseline and after one year under anti-rheumatic therapy (follow-up time 12.5±1.1 months) in a dedicated extremity MRI scanner at 0.2T were included in this retrospective study.
  
  
  RESULTS
  There was a strong correlation between RAMRIS5 and the RAMRIS sum-score for all patients (r=0.87, p<0.001) at baseline and follow-up (r=0.87, p<0.001). Among the subscores there was a significant correlation between RAMRIS5 and RAMRIS-MCP (baseline: r=0.66, p<0.001; follow-up: r=0.74, p<0.001) as well as between RAMRIS5 and RAMRIS-wrist (baseline: r=0.72, p<0.001, follow-up: r=0.69, p<0.001) at baseline and follow-up.
  
  
  CONCLUSIONS
  RAMRIS5, a modified shorter RAMRIS score based on five joints of the hand is a viable tool for semi-quantitative assessment of joint damage in RA. This abbreviated score might reduce the time needed for image analysis in MRI-controlled studies in RA and might facilitate the use of MRI in studies on therapy response assessment in RA.
authors: Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
authors: Christoph
authors: C
authors: Schleich
authors: Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
authors: Christian
authors: C
authors: Buchbender
authors: Department of Rheumatology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
authors: Philipp
authors: P
authors: Sewerin
authors: Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
authors: Falk
authors: F
authors: Miese
authors: Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
authors: Joel
authors: J
authors: Aissa
authors: Institute of Biometry and Epidemiology, German Diabetes Centre, Dusseldorf, Germany.
authors: Ralph
authors: R
authors: Brinks
authors: Department of Rheumatology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
authors: Matthias
authors: M
authors: Schneider
authors: Department of Diagnostic and Interventional Radiology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
authors: Gerald
authors: G
authors: Antoch
authors: Department of Rheumatology, University of Dusseldorf, Medical Faculty, Dusseldorf, Germany.
authors: Benedikt
authors: B
authors: Ostendorf
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D050823:Hand Joints / Q000187:drug effects / Q000473:pathology*; D006304:Health Status; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D018501:Antirheumatic Agents