title: Regio- and Stereoselective Direct Cross-Coupling of Aromatic Imines with Allenic Alcohols.
abstract: We describe a titanium-mediated reaction for the convergent coupling of allenic alcohols with aromatic imines. Overall, the bond formation occurs at the central carbon of the allene, proceeds with net allylic transposition, and provides substituted 1,3-dienes bearing allylic amine functionality in a regio- and stereoselective fashion.
authors: Department of Chemistry, Yale University, New Haven, CT 06520.
authors: Martin
authors: M
authors: McLaughlin
authors: Department of Chemistry, Yale University, New Haven, CT 06520.
authors: Heidi L
authors: HL
authors: Shimp
authors: Department of Chemistry, Yale University, New Haven, CT 06520.
authors: Raul
authors: R
authors: Navarro
authors: Department of Chemistry, Yale University, New Haven, CT 06520.
authors: Glenn C
authors: GC
authors: Micalizio
keywords: Imines; allenes; cross-coupling; metallacycles; titanium