title: A three-generation family with idiopathic facial palsy suggesting an autosomal dominant inheritance with high penetrance.
abstract: Idiopathic facial palsy (IFP), also known as Bell's palsy, is a common neurologic disorder, but recurrent and familial forms are rare. This case series presents a three-generation family with idiopathic facial palsy. The mode of inheritance of IFP has previously been suggested as autosomal dominant with low or variable penetrance, but the present family indicates an autosomal dominant trait with high or complete penetrance. Chromosome microarray studies did not reveal a pathogenic copy number variation, which could enable identification of a candidate gene.
authors: Department of Otorhinolaryngology, Head and Neck Surgery, Copenhagen University Hospital of Rigshospitalet, 2100 Copenhagen, Denmark.
authors: Christian
authors: C
authors: Grønhøj Larsen
authors: Department of Dermato-Allergology, Gentofte Hospital, University of Copenhagen, 2900 Hellerup, Denmark.
authors: Mette
authors: M
authors: Gyldenløve
authors: Clinical Genetic Clinic, Kennedy Center, Copenhagen University Hospital, Rigshospitalet, 2600 Glostrup, Denmark.
authors: Aia Elise
authors: AE
authors: Jønch
authors: Department of Otorhinolaryngology, Head and Neck Surgery, Copenhagen University Hospital of Rigshospitalet, 2100 Copenhagen, Denmark.
authors: Birgitte
authors: B
authors: Charabi
authors: Applied Human Molecular Genetics, Kennedy Center, Copenhagen University Hospital, Rigshospitalet, 2600 Glostrup, Denmark.
authors: Zeynep
authors: Z
authors: Tümer