title: A new aldehyde compound from the fruit of Pandanus tectorius Parkinson ex Du Roi.
abstract: From the fruit of Pandanus tectorius Parkinson ex Du Roi, one new (1) and six known aldehyde compounds (2-7) were isolated by various chromatography methods. Based on their spectroscopic data, these compounds were identified as (Z)-4-hydroxy-3-(4-hydroxy-3-methylbut-2-en-1-yl) benzaldehyde (1), p-hydroxybenzaldehyde (2), syringaldehyde (3), (E)-ferulaldehyde (4), (E)-sinapinaldehyde (5), vanillin (6) and 5-hydroxymethylfurfual (7). The α-glucosidase inhibitory activity of all compounds was measured. The isolated compounds (1-6) showed better α-glucosidase inhibitory activity (IC50 values ranging from 36.5 to 192.4 μM) than the standard drug acarbose (IC50 = 214.5 μM).
authors: a Bioactive Compounds Laboratory, Institute of Chemical Technology, Vietnam Academy of Science and Technology , 01 Mac Dinh Chi Street, District 1, Ho Chi Minh City , Vietnam.
authors: Dinh Tri
authors: DT
authors: Mai
authors: Tien Dung
authors: TD
authors: Le
authors: Tan Phat
authors: TP
authors: Nguyen
authors: Nhat Minh
authors: NM
authors: Phan
authors: Huu An
authors: HA
authors: Nguyen
authors: Thi Thanh Phuc
authors: TT
authors: Nguyen
authors: Le Quan
authors: le Q
authors: Tran
mesh_terms: D000447:Aldehydes / Q000737:chemistry* / Q000302:isolation & purification; D001547:Benzaldehydes / Q000737:chemistry* / Q000302:isolation & purification; D005638:Fruit / Q000737:chemistry*; D065089:Glycoside Hydrolase Inhibitors / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D031673:Pandanaceae / Q000737:chemistry*; D014744:Vietnam
chemical_list: C000601328:(Z)-4-hydroxy-3-(4-hydroxy-3-methylbut-2-en-1-yl)benzaldehyde; D000447:Aldehydes; D001547:Benzaldehydes; D065089:Glycoside Hydrolase Inhibitors
keywords: Pandanus tectorius; new aldehyde; α-glucosidase