title: Rubella Seroprevalence among the General Population in Dongguan, China.
abstract: In order to assess the immunity to rubella infection in Dongguan, China, we conducted a seroprevalence survey on rubella and used ELISA to measure rubella-specific IgG in serum samples. A total of 1,017 individuals aged 0-59 years were selected by multistage cluster sampling. Among them, 904 (88.9%) were seropositive for rubella. Two groups (20-29 and ≥40 years) had seropositivity rates of <90%. In comparison with participants aged ≥20 years, rubella immunization rates were higher in those aged <20 years (83.2% vs. 93.7%, respectively; χ(2) = 28.063, P < 0.001). Among women aged 20-29 years, only 63.8% had antibodies above the protective level. Multivariate analysis revealed that only sex and age were significantly associated with rubella-protective antibody levels. Our results suggest that in the study area, women of childbearing age had a greater serological susceptibility to rubella. Additional vaccinations for rubella of susceptible young adults should be considered, particularly in women of childbearing age.
authors: Department of Epidemiology and Biostatistics, Guangdong Medical College.
authors: Weiyan
authors: W
authors: Lin
authors: Dong
authors: D
authors: Wang
authors: Yongzhen
authors: Y
authors: Xiong
authors: Hao
authors: H
authors: Tang
authors: Zhengfa
authors: Z
authors: Liao
authors: Jindong
authors: J
authors: Ni
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D012409:Rubella / Q000453:epidemiology* / Q000276:immunology*; D012411:Rubella Vaccine / Q000276:immunology; D012412:Rubella virus / Q000276:immunology*; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D012411:Rubella Vaccine