title: Transient lesion in the splenium of the corpus callosum due to rotavirus infection.
abstract: Transient signal changes in magnetic resonance imaging (MRI) of the splenium of the corpus callosum (SCC) can result from many different reasons, including encephalitis and encephalopathy caused by infection, seizures, metabolic disorders and asphyxia. We report a case of a 6-year-old Polish girl with rotavirus infection demonstrating a reversible SCC lesion on diffusion-weighted MRI images. She presented six episodes of generalized tonic seizures with mild acute gastroenteritis. Stool test for rotavirus antigen was positive. At the time of admission imaging showed the hyperintense region in T2-weighted and fluid-attenuated inversion-recovery MRI, a well-defined lesion in the splenium of the corpus callosum with restricted diffusion in diffusion-weighted MRI and no enhancement in post contrast T1-weighted imaging. Her first EEG showed slow brain activity in the posterior occipitotemporal portion, consisting mainly of theta waves with a frequency of 4.5-5.5 Hz and amplitude of 40 uV. The lesion had completely disappeared on follow-up MRI 10 days later. The patient recovered fully without any sequelae.
authors: Department of Infectious Diseases and Child Neurology, Karol Marcinkowski University of Medical Sciences in Poznań, Szpitalna Street 27/33, 60-578, Poznań, Poland, katarzynam-m@wp.pl.
authors: Katarzyna
authors: K
authors: Mazur-Melewska
authors: Katarzyna
authors: K
authors: Jonczyk-Potoczna
authors: Krystyna
authors: K
authors: Szpura
authors: Grzegorz
authors: G
authors: Biegański
authors: Anna
authors: A
authors: Mania
authors: Paweł
authors: P
authors: Kemnitz
authors: Wojciech
authors: W
authors: Służewski
authors: Magdalena
authors: M
authors: Figlerowicz
mesh_terms: D001930:Brain Injuries / Q000209:etiology* / Q000473:pathology*; D002648:Child; D003337:Corpus Callosum / Q000473:pathology* / Q000821:virology; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D012401:Rotavirus / Q000472:pathogenicity*; D012400:Rotavirus Infections / Q000150:complications*