title: Treating obesity seriously: when recommendations for lifestyle change confront biological adaptations.
authors: Mount Sinai Adolescent Health Center, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY 10128, USA; New York Obesity Nutrition Research Center, Columbia University Medical Center, New York, NY, USA. Electronic address: christopher.ochner@mountsinai.org.
authors: Christopher N
authors: CN
authors: Ochner
authors: Kaiser Permanente of Colorado, Departments of Internal Medicine and Metabolic-Surgical Weight Management, Denver, CO, USA; University of Colorado School of Medicine, Division of General Internal Medicine, Aurora, CO, USA.
authors: Adam G
authors: AG
authors: Tsai
authors: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; Center for Lifestyle Medicine, Northwestern Medical Faculty Foundation, Chicago, IL, USA.
authors: Robert F
authors: RF
authors: Kushner
authors: Center for Weight and Eating Disorders, Department of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
authors: Thomas A
authors: TA
authors: Wadden
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D017667:Adipocytes / Q000502:physiology; D031204:Caloric Restriction; D049109:Cell Proliferation / Q000502:physiology; D004298:Dopamine / Q000502:physiology; D006185:Habituation, Psychophysiologic / Q000502:physiology; D006801:Humans; D008019:Life Style; D009765:Obesity / Q000628:therapy*; D015398:Signal Transduction; D017211:Treatment Failure
chemical_list: D004298:Dopamine