title: Nuclease resistant oligonucleotides with cell penetrating properties.
abstract: 2'-O-AECM modified oligonucleotides provide an unusual combination of remarkable properties. This includes the combination of high resistance towards enzymatic degradation and the spontaneous cellular uptake of AECM oligonucleotides.
authors: Karolinska Institutet, Department of Biosciences and Nutrition, Novum, Hälsovägen 7, SE-14183, Huddinge, Sweden. Roger.Stromberg@ki.se.
authors: Stefan
authors: S
authors: Milton
authors: Dmytro
authors: D
authors: Honcharenko
authors: Cristina S J
authors: CS
authors: Rocha
authors: Pedro M D
authors: PM
authors: Moreno
authors: C I Edvard
authors: CI
authors: Smith
authors: Roger
authors: R
authors: Strömberg
mesh_terms: D001692:Biological Transport; D045744:Cell Line, Tumor; D004950:Esterases / Q000378:metabolism*; D006801:Humans; D009841:Oligonucleotides / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D009841:Oligonucleotides; D004950:Esterases