title: Stable poly(St-co-BA) nanoemulsion polymerization for high performance antibacterial coatings in the presence of dioctyldimethylammonium chloride.
abstract: In this study, a stable antibacterial poly(styrene-co-butyl acrylate) (poly(St-co-BA)) nano-latex was prepared in the presence of a dioctyldimethylammonium chloride (D821)-CTAB mixed surfactant and a novel bis-unsaturated Gemini comonomer (i.e., α,ω-hexanediyl bis(dimethyl methacrylamidopropyl ammonium bromide) (GMAP-6-MAP)) using a feasible and mild semicontinuous technology. The effects of the emulsifiers and GMAP-6-MAP on the properties and antibacterial activities of poly(St-co-BA) coatings were systematically investigated. The results indicate that an optimal monodispersed stable nanoemulsion was obtained with Dw=58.24nm and PDI=0.026, the emulsifier amount was 3.75% (D821/CTAB=4:1), and the GMAP-6-MAP amount was 1.5%. CTAB improved the stabilities and antibacterial activities of the poly(St-co-BA) nanoemulsions. The incorporation of GMAP-6-MAP into poly(St-co-BA) can enhance the antibacterial activity, improve the thermal stability of latex films, as well as the consistency among the chain segments, and decrease the roughness of latex films. This nanoemulsion exhibits effective antibacterial activity with MBCs of 2μg·mL(-1) against Staphylococcus aureus and 16μg·mL(-1) against Escherichia coli. The sterilization rates of the optimized latex film reached 100% against S. aureus and 98.74% against E. coli, which indicated that this latex film could be utilized as an outstanding antibacterial coating.
authors: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, College of Chemistry and Chemical Engineering, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University, Wuhan 430062, China.
authors: Zhao
authors: Z
authors: Chen
authors: Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Faculty of Life Science, Hubei University, Wuhan 430062, China.
authors: Xiaowen
authors: X
authors: Sun
authors: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, College of Chemistry and Chemical Engineering, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University, Wuhan 430062, China.
authors: Yan
authors: Y
authors: Shen
authors: Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, Faculty of Life Science, Hubei University, Wuhan 430062, China.
authors: Hong
authors: H
authors: Ni
authors: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, College of Chemistry and Chemical Engineering, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University, Wuhan 430062, China.
authors: Shigan
authors: S
authors: Chai
authors: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, College of Chemistry and Chemical Engineering, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University, Wuhan 430062, China.
authors: Qichao
authors: Q
authors: Zou
authors: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, College of Chemistry and Chemical Engineering, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University, Wuhan 430062, China.
authors: Xiuhua
authors: X
authors: Zhang
authors: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, College of Chemistry and Chemical Engineering, Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University, Wuhan 430062, China. Electronic address: zjz4000@126.com.
authors: Jinzhi
authors: J
authors: Zhang
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D001965:Bromides / Q000737:chemistry; D004926:Escherichia coli / Q000187:drug effects; D007840:Latex / Q000737:chemistry; D008826:Microbial Sensitivity Tests / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D058105:Polymerization; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D020058:Styrene / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry
chemical_list: D000179:Acrylates; D000900:Anti-Bacterial Agents; D001965:Bromides; D007840:Latex; D000644:Quaternary Ammonium Compounds; D013501:Surface-Active Agents; C473737:dioctyldimethyl ammonium chloride; D020058:Styrene; C032490:n-butyl acrylate; C051470:ammonium bromide
keywords: Antibacterial coatings; Bis-unsaturated Gemini comonomer; CTAB; Dioctyldimethylammonium chloride; Mixed surfactant system; Poly(styrene-co-butyl acrylate)