title: Effect of inhaled corticosteroids on glycemic status.
abstract: Although the dysglycemic effects of systemic glucocorticoid therapy are well known, the effect of inhaled corticosteroids (ICS) on carbohydrate metabolism is still a subject of debate. The systemic bioavailability of ICS is claimed to be minimal and the side effects negligible. However, some large retrospective cohort studies showed a definite association between ICS use and incident diabetes or worsening glycemic control in pre-existing diabetes. There are no professional-body recommended guidelines on the diagnosis and management of steroid-induced diabetes for the general population. This review aims to evaluate the systemic dysglycemic effect of ICS treatment and to propose a management algorithm.
authors: Department of Medicine, University Hospital of North Staffordshire, ST4 6QG, UK.
authors: Francis
authors: F
authors: Egbuonu
authors: Department of Medicine, University Hospital of North Staffordshire, ST4 6QG, UK.
authors: Farrah A
authors: FA
authors: Antonio
authors: Department of Endocrinology & Diabetes, University Hospital of North Staffordshire, ST4 6QG, UK.
authors: Mahamood
authors: M
authors: Edavalath
keywords: Diabetes control; diabetes mellitus; dysglycemic status; hyperglycemia; inhaled corticosteroids (ICS); steroid-induced diabetes.