title: Two new eudesmane-type glucopyranosides from the fruits of Daucus carota L.
abstract: Two new eudesmane-type glucopyranosides have been isolated from the fruits of Daucus carota L. On the basis of their spectroscopic and chemical evidence, the new compounds were elucidated as daucucarotol-10-O-β-D-glucopyranoside (1) and decahydro-7-[(2-O-β-D-glucopyranosyl)-isopropyl]-1β,4aα-dimethyl-(1α,4α,8aβ)-naphthalenetriol (2). Compounds 1 and 2 showed moderate antitumour activity against human ECA-109 and gave IC50 values of 23.22 and 26.76 μM, respectively.
authors: a Shandong Center for Disease Control and Prevention , Jinan 250014 , P.R. China.
authors: Jin-Ke
authors: JK
authors: Xu
authors: Xiang-Hong
authors: XH
authors: Lu
authors: Wei
authors: W
authors: Zhu
authors: Bing-Xian
authors: BX
authors: Yang
authors: Lin
authors: L
authors: Zhang
authors: Jing-Kui
authors: JK
authors: Tian
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification; D045744:Cell Line, Tumor; D018552:Daucus carota / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D006801:Humans; D015394:Molecular Structure; D045787:Sesquiterpenes, Eudesmane / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D005960:Glucosides; D045787:Sesquiterpenes, Eudesmane; C000603292:daucucarotol-10-O-glucopyranoside; C000603293:decahydro-7-((2-O-glucopyranosyl)isopropyl)-1,4a-dimethyl-(1,4,8a)-naphthalenetriol; C015872:eudesmane
keywords: Daucus carota L; antitumour activity; eudesmane type sesquiterpene glycoside