title: Independent evaluation of a canine Echinococcosis Control Programme in Hobukesar County, Xinjiang, China.
abstract: The Xinjiang Uyghur Autonomous Region in northwest China is one of the world's most important foci for cystic echinococcosis. Domestic dogs are the main source for human infection, and previous studies in Xinjiang have found a canine Echinococcus spp. coproELISA prevalence of between 36% and 41%. In 2010 the Chinese National Echinococcosis Control Programme was implemented in Xinjiang, and includes regular dosing of domestic dogs with praziquantel. Six communities in Hobukesar County, northwest Xinjiang were assessed in relation to the impact of this control programme through dog necropsies, dog Echinococcus spp. coproantigen surveys based on Lot Quality Assurance Sampling (LQAS) and dog owner questionnaires. We found that 42.1% of necropsied dogs were infected with Echinococcus granulosus, and coproELISA prevalences were between 15% and 70% in the communities. Although approximately half of all dog owners reported dosing their dogs within the 12 months prior to sampling, coproELISA prevalence remained high. Regular praziquantel dosing of owned dogs in remote and semi-nomadic communities such as those in Hobukesar County is logistically very difficult and additional measures should be considered to reduce canine echinococcosis.
authors: Cestode Zoonoses Research Group, School of Environment and Life Sciences, University of Salford, M5 4WT Salford, UK. Electronic address: Freyavankesteren@gmail.com.
authors: Freya
authors: F
authors: van Kesteren
authors: State Key Lab Incubation Base for Xinjiang Major Diseases Research and Xinjiang Key Laboratory of Echinococcosis, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
authors: Xinwei
authors: X
authors: Qi
authors: State Key Lab Incubation Base for Xinjiang Major Diseases Research and Xinjiang Key Laboratory of Echinococcosis, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
authors: Jiang
authors: J
authors: Tao
authors: State Key Lab Incubation Base for Xinjiang Major Diseases Research and Xinjiang Key Laboratory of Echinococcosis, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
authors: Xiaohui
authors: X
authors: Feng
authors: Cestode Zoonoses Research Group, School of Environment and Life Sciences, University of Salford, M5 4WT Salford, UK.
authors: Alexander
authors: A
authors: Mastin
authors: Cestode Zoonoses Research Group, School of Environment and Life Sciences, University of Salford, M5 4WT Salford, UK.
authors: Philip S
authors: PS
authors: Craig
authors: WHO-Collaborating Centre for Prevention and Treatment of Human Echinococcosis, France.
authors: Dominique A
authors: DA
authors: Vuitton
authors: State Key Lab Incubation Base for Xinjiang Major Diseases Research and Xinjiang Key Laboratory of Echinococcosis, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
authors: Xinyu
authors: X
authors: Duan
authors: People's Hospital of Hobukesar County, Hobukesar, Xinjiang, China.
authors: Xiangdong
authors: X
authors: Chu
authors: People's Hospital of Hobukesar County, Hobukesar, Xinjiang, China.
authors: Jinlong
authors: J
authors: Zhu
authors: State Key Lab Incubation Base for Xinjiang Major Diseases Research and Xinjiang Key Laboratory of Echinococcosis, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China. Electronic address: dr.wenhao@163.com.
authors: Hao
authors: H
authors: Wen
mesh_terms: D000818:Animals; D002681:China / Q000453:epidemiology; D004283:Dog Diseases / Q000188:drug therapy* / Q000453:epidemiology*; D004285:Dogs; D004443:Echinococcosis / Q000188:drug therapy / Q000453:epidemiology* / Q000662:veterinary*; D048209:Echinococcus granulosus / Q000187:drug effects*; D006801:Humans; D055810:Lot Quality Assurance Sampling; D011223:Praziquantel / Q000627:therapeutic use*; D015995:Prevalence; D011795:Surveys and Questionnaires; D015047:Zoonoses / Q000517:prevention & control*
chemical_list: D011223:Praziquantel
keywords: Control programme; Domestic dogs; Echinococcus granulosus; Lot Quality Assurance Sampling; Xinjiang