title: Triphenylarsonium-functionalised gold nanoparticles: potential nanocarriers for intracellular therapeutics.
abstract: Two new triphenylarsonium alkylthiolate precursors, a thiosulfate zwitterion and a thioacetate salt, have been structurally characterised and their cytotoxicity evaluated against PC3 cells. The arsonium compounds have been used to prepare gold nanoparticles decorated with triphenylarsonium groups.
authors: Biomedical Research Centre, Sheffield Hallam University, City Campus, Sheffield S1 1WB, UK. n.bricklebank@shu.ac.uk.
authors: Nikhil
authors: N
authors: Lalwani
authors: Yu-Su
authors: YS
authors: Chen
authors: Gemma
authors: G
authors: Brooke
authors: Neil A
authors: NA
authors: Cross
authors: David W
authors: DW
authors: Allen
authors: Alan
authors: A
authors: Reynolds
authors: Jesús
authors: J
authors: Ojeda
authors: Graham J
authors: GJ
authors: Tizzard
authors: Simon J
authors: SJ
authors: Coles
authors: Neil
authors: N
authors: Bricklebank
mesh_terms: D001152:Arsenicals / Q000737:chemistry* / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004337:Drug Carriers / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D006801:Humans; D042541:Intracellular Space / Q000187:drug effects*; D053768:Metal Nanoparticles / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D013431:Sulfates / Q000737:chemistry
chemical_list: D001152:Arsenicals; D004337:Drug Carriers; D013431:Sulfates; D006046:Gold