title: The cardiovascular effects of colchicine: a comprehensive review.
abstract: Colchicine is used extensively in the treatment of autoimmune and inflammatory disorders. Recent data have demonstrated additional benefit in a variety of cardiovascular disorders, including acute and recurrent pericarditis, postpericardiotomy syndrome, atrial fibrillation, stable ischemic heart disease, and possibly chronic heart failure. This article serves as a focused and updated discussion on the cardiovascular effects of colchicine and emphasizes the importance of randomized, placebo-controlled trials to further our clinical and pharmacological understanding of these findings.
authors: From the *Columbia University Division of Cardiology, The Mount Sinai Heart Institute, Mount Sinai Medical Center, Miami Beach, FL; and †Department of Internal Medicine, Nova Southeastern University College of Osteopathic Medicine, Fort Lauderdale, FL.
authors: Paola
authors: P
authors: Casanova
authors: Rosa T
authors: RT
authors: Artola
authors: Christos G
authors: CG
authors: Mihos
authors: Andres M
authors: AM
authors: Pineda
authors: Orlando
authors: O
authors: Santana
mesh_terms: D001281:Atrial Fibrillation / Q000188:drug therapy; D002316:Cardiotonic Agents / Q000627:therapeutic use*; D003078:Colchicine / Q000627:therapeutic use*; D003324:Coronary Artery Disease / Q000188:drug therapy; D006074:Gout Suppressants / Q000627:therapeutic use*; D006331:Heart Diseases / Q000188:drug therapy*; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D010493:Pericarditis / Q000188:drug therapy; D016032:Randomized Controlled Trials as Topic
chemical_list: D002316:Cardiotonic Agents; D006074:Gout Suppressants; D003078:Colchicine