title: IL-6 and CRP response to maximal exercise intervention.
abstract: OBJECTIVE
  The purpose of this study was to investigate the recovery pattern of the plasma inflammatory markers interleukin-6 (IL-6) and C-reactive protein (CRP) after the single-bout maximal exercise. The exercise of different type (continuous vs. intermittent) was performed and also compared in this study.
  
  
  METHODS
  Following baseline testing, 30 males were divided into three experimental groups, which completed continuous or intermittent all-out exercise of similar duration or no exercise intervention (Control group). Blood was sampled before and 1 h, 3 h, 5 h after exercise. Serum was analysed for IL-6, CRP, lactate, creatinine, uric acid, cortisol, creatine kinase, lactate dehydrogenase and myoglobin. Diet was standardized during recovery monitoring.
  
  
  RESULTS
  Serum IL-6 and CRP concentrations were not significantly changed in the pre- to post-exercise values comparison. These results are evident in both exercise intervention groups as well as in the control group. The only exception is the significant (P=0.03) IL-6 decrease (28.2%) in continuous exercise protocol 3 h after the exercise. Significant changes (P<0.05) were also observed in lactate, cortisol, uric acid and myoglobin, when pre-exercise vs. post-exercise recovery values were compared
  
  
  CONCLUSIONS
  The exercise of all-out intensity and relatively short duration, no matter what type, does not elicit a significant change in the inflammatory markers IL-6 and CRP for the 1h to 5h period of rest following the exercise.
authors: Ostrava University, Human Motion Diagnostic Centre, Ostrava, Czech Republic - lukas.cipryan@osu.cz.
authors: L
authors: L
authors: Cipryan
authors: Z
authors: Z
authors: Svagera
authors: R
authors: R
authors: Vala
mesh_terms: D000886:Anthropometry; D015415:Biomarkers / Q000378:metabolism; D002097:C-Reactive Protein / Q000378:metabolism*; D016022:Case-Control Studies; D003402:Creatine Kinase / Q000378:metabolism; D003404:Creatinine / Q000378:metabolism; D015444:Exercise / Q000502:physiology*; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D015850:Interleukin-6 / Q000378:metabolism*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D009211:Myoglobin / Q000378:metabolism; D014527:Uric Acid / Q000378:metabolism; D055815:Young Adult
chemical_list: D015415:Biomarkers; D015850:Interleukin-6; D009211:Myoglobin; D014527:Uric Acid; D002097:C-Reactive Protein; D003404:Creatinine; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase; D006854:Hydrocortisone