title: [Movement disorders due to modern antidepressants and mood stabilizers].
abstract: BACKGROUND
  Personal experience and recent literature indicate that clinicians often underestimate the severity and the range of movement disorders that can result from treatment with antidepressants and mood stabilisers.
  
  
  OBJECTIVE
  To describe the prevalence, nature, symptoms and treatment of the movement disorders arising from the use of antidepressants and mood stabilisers.
  
  
  METHODS
  We searched Medline for relevant case-reports (patients > 18 years) and review articles for the period 1966 - January 2014). Our search was based on the search-terms '(drug-induced) movement disorders' and 'extrapyramidal symptoms', 'antidepressants', 'mood stabilisers', 'antiepileptics' and 'lithium'. The results were supplemented by movement disorders reported in the database of The Netherlands Pharmacovigilance Centre Lareb.
  
  
  RESULTS
  The most prevalent side-effects were found to be tremor, acathisia, dystonia and (tardive) dyskinesia.
  
  
  CONCLUSIONS
  The clinician needs to be aware of the movement disorders that can result from treatment with antidepressants and mood stabilisers. Symptoms can generally be alleviated by adjusting the prescribed medication or sometimes by stopping the principal causal agent completely.
authors: W
authors: W
authors: Vandewalle
authors: E
authors: E
authors: Boon
authors: P
authors: P
authors: Sienaert
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D009069:Movement Disorders / Q000209:etiology*; D060735:Pharmacovigilance
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents