title: [Microbiological efficacy of a one-day treatment with triazole antimycotic I traconazole in mycotic colpitis].
abstract: BACKGROUND
  Fungal colpitis is the most common inflammatory disease of the vagina, whose proportion in the different groups of the patients ranges from 30% to 60%. The major cause is genus Candida. In 80% to 95% of the cases the reason is Candida albicans species and in 10% to 20%--the representatives of the species Candida Non-albicans. One problem that arises in this genital infection is the insufficient effectiveness of the drug treatment in many of the cases.
  
  
  RESULTS
  This study is a prospective and monitors 40 non-pregnant women, accounting therapeutic effect of Itraconazol in fungal colpitis. Patients had administered treatment with Itraconazol 2 x 200 mg/1 day, per oral. Microbiological testing was performed prior to the treatment and 2 to 4 weeks after completion of the therapy. We found C. albicans in 75% of the cases and in 25%--C. non-albicans (C. glabrata, C. kefyr, C. krusei, C. famata). In the group of C. albicans, good therapeutic efficiency was observed in 93.3% of the cases, while in patients with C. non-albicans it was in 80% of the cases.
  
  
  CONCLUSIONS
  Itraconazol showed sufficiently high therapeutic effect for patients with fungal colpitis, it proved to be suitable for patients with Candida albicans and also in the cases with Candida non-albicans.
authors: P
authors: P
authors: Andreeva
authors: D
authors: D
authors: Savova
authors: M
authors: M
authors: Konovalova
authors: M
authors: M
authors: Unakova
authors: A
authors: A
authors: Shterev
mesh_terms: D000284:Administration, Oral; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002175:Candida / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects; D002177:Candidiasis / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage / Q000627:therapeutic use*; D011446:Prospective Studies; D014621:Vagina / Q000382:microbiology; D014627:Vaginitis / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole