title: Copper-catalyzed enantioselective propargylic etherification of propargylic esters with alcohols.
abstract: Enantioselective propargylic etherification of propargylic esters with not only aliphatic alcohols but also phenols in the presence of a catalytic amount of copper-Pybox complex gives the corresponding propargylic ethers in good to high yields with a high to excellent enantioselectivity (up to 99% ee). The result described here provides the first successful example of enantioselective propargylic etherification.
authors: Institute of Engineering Innovation, School of Engineering, The University of Tokyo , Yayoi, Bunkyo-ku, Tokyo, 113-8656, Japan.
authors: Kazunari
authors: K
authors: Nakajima
authors: Masashi
authors: M
authors: Shibata
authors: Yoshiaki
authors: Y
authors: Nishibayashi