title: Regression of Hepatocellular Carcinoma Lung Metastases after Guyabano Fruit Extract Consumption.
abstract: Hepatocellular carcinoma (HCC) is a leading cause of worldwide cancer-related mortality, and even with established treatment paradigms, its global burden demands greater research into therapeutic options. In the following case report, a patient suffering from HCC with lung metastasis demonstrated regression of metastatic disease while consuming guyabano fruit extract in the absence of conventional chemotherapy. While the antineoplastic effects of the guyabano fruit is well documented, there is sparse clinical documentation of HCC regression associated with it, and a better understanding of guyabano and its antineoplastic activity may trigger discovery of novel therapeutic options for this deadly disease.
authors: a 1 Division of Interventional Radiology, Department of Radiology, University of Illinois Hospital and Health Sciences System , Chicago, Illinois, USA.
authors: Senthil S
authors: SS
authors: Gunasekaran
authors: b 2 Department of Pathology, University of Illinois Hospital and Health Sciences System , Chicago, Illinois, USA.
authors: Rajyasree
authors: R
authors: Emmadi
authors: a 1 Division of Interventional Radiology, Department of Radiology, University of Illinois Hospital and Health Sciences System , Chicago, Illinois, USA.
authors: Lisa A
authors: LA
authors: Landers
authors: a 1 Division of Interventional Radiology, Department of Radiology, University of Illinois Hospital and Health Sciences System , Chicago, Illinois, USA.
authors: Ron C
authors: RC
authors: Gaba
mesh_terms: D031041:Annona; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000178:diet therapy / Q000188:drug therapy*; D005638:Fruit; D006801:Humans; D008113:Liver Neoplasms / Q000178:diet therapy / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D008517:Phytotherapy; D012074:Remission Induction
chemical_list: D000972:Antineoplastic Agents, Phytogenic
keywords: guyabano; hepatocellular carcinoma (HCC); lung; metastases; regression