title: Particular aspects of proctology for anoperineal lesions in Crohn's disease.
abstract: All practitioners caring for patients with Crohn's disease (CD) must know all the various aspects of anoperineal lesions in this singular entity. Suppuration in CD does not follow the classic routes and spaces of diffusion and is often associated with endolumenal lesions that can evolve on their own. Abscesses and fistulas require specific medico-surgical management where seton drainage, staged operative and sphincter-sparing procedures have a dominant place. The variability of associated lesions and the particularly individualized efficacy of drugs call for case-by-case management, thus, making standardization and comparisons difficult. Recent therapeutic progress has led to modifications of the minimally invasive management policies practiced in the last decades.
authors: Service de proctologie médico-interventionnelle, groupe hospitalier Diaconesses-Croix Saint-Simon, 125, rue d'Avron, 75020 Paris, France. Electronic address: proctologie@hopital-dcss.org.
authors: P
authors: P
authors: Atienza
authors: Service de gastroentérologie, CHU Sahloul, Sousse, Tunisia.
authors: M
authors: M
authors: Ksiaa
mesh_terms: D000038:Abscess / Q000209:etiology / Q000628:therapy*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001004:Anus Diseases / Q000209:etiology / Q000628:therapy*; D001005:Anus Neoplasms / Q000628:therapy; D003107:Colorectal Surgery; D003424:Crohn Disease / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D004322:Drainage / Q000379:methods; D004359:Drug Therapy, Combination; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use; D006801:Humans; D000069285:Infliximab / Q000627:therapeutic use; D059351:Organ Sparing Treatments; D010502:Perineum / Q000473:pathology / Q000601:surgery; D012003:Rectal Fistula / Q000209:etiology / Q000628:therapy*; D012004:Rectal Neoplasms / Q000473:pathology / Q000628:therapy*; D012006:Rectovaginal Fistula / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D005765:Gastrointestinal Agents; D000069285:Infliximab
keywords: Anal fistula; Anoperineal lesions; Anti-TNFα; Crohn's disease; Immunosuppression