title: Acute response to psychological trauma and subsequent recovery: no changes in brain structure.
abstract: We used magnetic resonance imaging to study brain structure in acute stress disorder (ASD) following a psychological trauma and after 4 weeks in remission. Whole-brain voxel-based morphometry and FreeSurfer analysis of the hippocampal formation and amygdala revealed no structural changes in ASD (n=75) compared with trauma-exposed individuals without ASD (n=60) and community controls (n=60). These results suggest that ASD, in contrast to posttraumatic stress disorder, is not characterized by structural brain alterations.
authors: Nyírő Gyula Hospital - National Institute of Psychiatry and Addictions, Budapest, Hungary.
authors: Csilla
authors: C
authors: Szabó
authors: Bács-Kiskun County Hospital, Psychiatry Center, Kecskemét, Hungary.
authors: Oguz
authors: O
authors: Kelemen
authors: Nyírő Gyula Hospital - National Institute of Psychiatry and Addictions, Budapest, Hungary; Institute for the Study of Affective Neuroscience, University of Haifa, Haifa, Israel.
authors: Einat
authors: E
authors: Levy-Gigi
authors: Nyírő Gyula Hospital - National Institute of Psychiatry and Addictions, Budapest, Hungary; Department of Physiology, Faculty of Medicine, University of Szeged, Szeged, Hungary; Budapest University of Technology and Economics, Department of Cognitive Science, Budapest, Hungary. Electronic address: keri.szabolcs.gyula@med.u-szeged.hu.
authors: Szabolcs
authors: S
authors: Kéri
mesh_terms: D000328:Adult; D000679:Amygdala / Q000033:anatomy & histology*; D005260:Female; D006624:Hippocampus / Q000033:anatomy & histology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D012075:Remission, Spontaneous; D040701:Stress Disorders, Traumatic, Acute
keywords: Acute stress disorder; Amygdala; Brain volume; Hippocampus; Magnetic resonance imaging (MRI); Trauma