title: Intrapartum fever, epidural analgesia and histologic chorioamnionitis.
abstract: OBJECTIVE
  Our objective was to determine whether epidural analgesia and histologic chorioamnionitis were independent predictors of intrapartum fever.
  
  
  METHODS
  This secondary analysis, retrospective cohort study included term parturients with placental examination during 2005. Logistic regression used fever (⩾38 °C) as the dependent variable. Significance was defined as P⩽0.05.
  
  
  RESULTS
  There were 488 (76%) of 641 term parturients with placental examination and epidural. Independent predictors of intrapartum fever were epidural odds ratio (OR)=3.4, confidence interval (CI): 1.70, 6.81, histologic chorioamnionitis OR=3.18, 95% CI: 2.04, 4.95, birthweight OR=2.07, 95%CI: 1.38, 3.12, vaginal exams OR=1.15, 95% CI:1.06, 1.24, duration ruptured membranes OR=1.03, 95% CI: 1.01,1.05, parity⩾1 OR=0.44: 0.29, 0.66 and thick meconium OR=0.35: 95%CI: 0.24, 0.85.
  
  
  CONCLUSIONS
  Epidural analgesia and histologic chorioamnionitis were independent predictors of intrapartum fever. Modification of labor management may reduce the incidence of intrapartum fever.
authors: 1] Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, University of Rochester School of Medicine & Dentistry, Rochester, NY, USA [2] Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, Pennsylvania State University College of Medicine, Hershey, PA, USA.
authors: W M
authors: WM
authors: Curtin
authors: Department of Pathology & Laboratory Medicine, University of Rochester School of Medicine & Dentistry, Rochester, NY, USA.
authors: P J
authors: PJ
authors: Katzman
authors: Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, University of Rochester School of Medicine & Dentistry, Rochester, NY, USA.
authors: H
authors: H
authors: Florescue
authors: Department of Pathology & Laboratory Medicine, University of Rochester School of Medicine & Dentistry, Rochester, NY, USA.
authors: L A
authors: LA
authors: Metlay
authors: Division of Maternal-Fetal Medicine, Department of Obstetrics & Gynecology, Pennsylvania State University College of Medicine, Hershey, PA, USA.
authors: S H
authors: SH
authors: Ural
mesh_terms: D000328:Adult; D015360:Analgesia, Epidural / Q000009:adverse effects; D002821:Chorioamnionitis / Q000453:epidemiology*; D005260:Female; D005334:Fever / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D015999:Multivariate Analysis; D007744:Obstetric Labor Complications / Q000209:etiology*; D011247:Pregnancy; D012189:Retrospective Studies; D055815:Young Adult