title: Urinary tract infections in the infant.
abstract: Urinary tract infection (UTI) in an infant may be the first indication of an underlying renal disorder. Early recognition and initiation of adequate therapy for UTI is important to reduce the risk of long-term renal scarring. Ampicillin and gentamicin are traditionally the empiric treatment of choice; however, local antibiotic resistance patterns should be considered. Maternal antibiotics during pregnancy also increase the risk of resistant pathogens during neonatal UTI. Long-term management after the first UTI in infants remains controversial because of lack of specific studies in this age group and the risk-benefit issues for antibiotic prophylaxis between reduced recurrent disease and emergent antibiotic resistance.
authors: Division of Infectious Diseases, Department of Pediatrics, Duke University School of Medicine, DUMC 3499, Durham, NC 27710, USA.
authors: Mehreen
authors: M
authors: Arshad
authors: Division of Infectious Diseases, Department of Pediatrics, Duke University School of Medicine, DUMC 3499, Durham, NC 27710, USA. Electronic address: patrick.seed@duke.edu.
authors: Patrick C
authors: PC
authors: Seed
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D002177:Candidiasis / Q000188:drug therapy* / Q000209:etiology; D002944:Circumcision, Male; D024881:Drug Resistance, Bacterial; D004927:Escherichia coli Infections / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D014564:Urogenital Abnormalities / Q000150:complications / Q000175:diagnosis; D014718:Vesico-Ureteral Reflux / Q000150:complications / Q000175:diagnosis*
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotic resistance; Escherichia coli; Infants; Renal imaging; Urinary tract infection; Vesicoureteral reflux