title: Two percent ethylenediaminetetraacetic acid chelation treatment for band-shaped keratopathy, without blunt scratching after removal of the corneal epithelium.
abstract: BACKGROUND
  The purpose of this study was to assess the effectiveness of 2% ethylenediaminetetraacetic acid (EDTA) for the treatment of band-shaped keratopathy.
  
  
  METHODS
  We studied 24 eyes of 16 patients with band-shaped keratopathy who underwent EDTA chelation treatment from April 1, 2011 to December 31, 2012. We compared preoperative and 1 month postoperative logarithm of the minimum angle of resolution (logMAR) best corrected visual acuity, intraocular pressure, and corneal curvature radius (K1, horizontal meridian; K2, vertical meridian; Km, average of K1 and K2). The Mann-Whitney U-test was used to determine the significance of differences.
  
  
  RESULTS
  There was a significant difference in preoperative and postoperative logMAR best corrected visual acuity (P=0.01). There were no significant differences in preoperative and postoperative intraocular pressure (P=0.24) or corneal curvature radius (K1, P=0.54; K2, P=0.49; Km, P=0.45).
  
  
  CONCLUSIONS
  After 2% EDTA chelation treatment, post-operative logMAR best corrected visual acuity improved significantly. Moreover, since there was no significant difference in corneal curvature radius, there was little influence on corneal surface form. We believe that the results of our 2% EDTA chelation treatment were comparable with results obtained with 3.75% EDTA chelation treatment in previous reports. Two percent EDTA chelation is an effective treatment for band-shaped keratopathy and a useful method for any institution.
authors: Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
authors: Wataru
authors: W
authors: Kobayashi
authors: Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
authors: Shunji
authors: S
authors: Yokokura
authors: Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan.
authors: Takehiro
authors: T
authors: Hariya
authors: Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan ; Department of Retinal Disease Control, Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan ; Department of Advanced Ophthalmic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan.
authors: Toru
authors: T
authors: Nakazawa
keywords: band-shaped keratopathy; cornea; ethylenediaminetetraacetic acid; phototherapeutic keratectomy