title: New fatty acid, aromatic ester and monoterpenic benzyl glucoside from the fruits of Withania coagulans Dunal.
abstract: The fruits of Withania coagulans Dunal (family: Solanaceae) are sweet, sedative, emetic, alterative and diuretic; used to treat asthma, biliousness, strangury, wounds, dyspepsia, flatulent colic, liver complaints and intestinal infections in the indigenous system of medicine. Phytochemical investigation of the methanolic extract of W. coagulans fruits led to the isolation of a new fatty acid, an aromatic ester and a monoterpenic benzyl glucoside characterised as n-octatriacont-17-enoic acid (3), geranilan-10-olyl dihydrocinnamoate (4) and geranilan-8-oic acid-10-olyl salicyloxy-2-O-β-D-glucofuranosyl-(6″→1‴)-O-β-D-glucofuranosyl-6‴-n-octadec-9‴',11‴'-dienoate (5) along with two known fatty acids, n-dotriacont-21-enoic acid (1) and n-tetratriacontanoic acid (2). The structures of isolated phytoconstituents were established on the basis of 1D and 2D NMR, FT-IR, UV, and MS data and chemical means.
authors: a Phytochemistry Research Laboratory, Department of Pharmacognosy and Phytochemistry , Faculty of Pharmacy, Jamia Hamdard , New Delhi 110 062 , India.
authors: Abuzer
authors: A
authors: Ali
authors: Mohammad
authors: M
authors: Jameel
authors: Mohammed
authors: M
authors: Ali
mesh_terms: D004952:Esters / Q000737:chemistry* / Q000302:isolation & purification; D005227:Fatty Acids / Q000737:chemistry* / Q000302:isolation & purification; D005638:Fruit / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D032341:Withania / Q000737:chemistry*
chemical_list: D004952:Esters; D005227:Fatty Acids; D005960:Glucosides
keywords: Indian rennet; Solanaceae; Withania coagulans; aromatic ester; fatty acid