title: Expression prolife and role of miRNAs in prostate cancer.
abstract: miRNAs are a class of noncoding RNA molecules about 18-25 nt in length. As key gene expression regulatory factors, they may inhibit or degrade mRNA by incompletely or completely complement to mRNA. Their abnormal expressions are closely related with the carcinogenesis of prostate cancer (PCa). Some miRNAs trigger cancer, while others inhibit the malignant changes. In this article we summarize the latest information on miRNAs expression prolifing and potential biomarkers,in particular the roles of miRNAs in PCa.
authors: Laboratory of Molecular Biology, Medical Research Center of Shaoxing People's Hospital, Shaoxing, Zhejiang 312000, China.
authors: Chun-jiao
authors: CJ
authors: Song
authors: Laboratory of Genomics, Zhejiang Institute of Microbiology, Hangzhou 310012, China.
authors: Huan
authors: H
authors: Chen
authors: Department of Pathology, Medical College of Shaoxing University, Shaoxing, Zhejiang 312000, China.
authors: Qiao-ying
authors: QY
authors: Zhang
authors: Department of Urology, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310012, China.
authors: Xiao-cao
authors: XC
authors: Shen
mesh_terms: D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008297:Male; D035683:MicroRNAs; D011471:Prostatic Neoplasms; D012333:RNA, Messenger
chemical_list: D035683:MicroRNAs; D012333:RNA, Messenger