title: Sublingual misoprostol is as effective as intravenous oxytocin to reduce intra-operative blood loss during cesarean delivery in women living at high altitude.
abstract: OBJECTIVE
  To assess the effect of sublingual misoprostol compared to intravenous oxytocin for blood loss during cesarean delivery in women living at high altitude.
  
  
  METHODS
  In a randomized trial, conducted in Quito, Ecuador (2800 m above sea level), 100 women received either sublingual misoprostol (400 µg) or intravenous oxytocin (10 IU).
  
  
  RESULTS
  Bleeding in the misoprostol was no different than in the oxytocin group. Shivering was reported in 66% of women in the misoprostol group.
  
  
  CONCLUSIONS
  Sublingual misoprostol might be a valid alternative to oxytocin reduce intra-operative blood loss during cesarean section in women living at high altitude.
authors: a Hospital Gineco-Obstetrico Isidro Ayora , Quito , Ecuador and.
authors: Patricio
authors: P
authors: Gavilanes
authors: a Hospital Gineco-Obstetrico Isidro Ayora , Quito , Ecuador and.
authors: Maria Fernanda
authors: MF
authors: Morales
authors: a Hospital Gineco-Obstetrico Isidro Ayora , Quito , Ecuador and.
authors: Stiward
authors: S
authors: Velasco
authors: b Colegio de Ciencias de la Salud, Universidad San Francisco de Quito , Quito , Ecuador.
authors: Enrique
authors: E
authors: Teran
mesh_terms: D000286:Administration, Sublingual; D000328:Adult; D000531:Altitude; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D002585:Cesarean Section; D004484:Ecuador; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D016595:Misoprostol / Q000627:therapeutic use*; D010120:Oxytocics / Q000627:therapeutic use*; D010121:Oxytocin / Q000627:therapeutic use*; D011247:Pregnancy; D011446:Prospective Studies; D012768:Shivering
chemical_list: D010120:Oxytocics; D016595:Misoprostol; D010121:Oxytocin
keywords: Cesarean delivery; cesarean section; high altitude; intra-operative bleeding; sublingual misoprostol