title: A new role for an old enemy.
abstract: Drugs that change the shape of AKT, a protein kinase that promotes tumor growth, may be more effective than drugs that only target its enzymatic activity.
authors: Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.
authors: Richard M
authors: RM
authors: Monaghan
authors: Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom, alan.j.whitmarsh@manchester.ac.uk.
authors: Alan J
authors: AJ
authors: Whitmarsh
mesh_terms: D002470:Cell Survival; D006801:Humans; D008545:Melanoma / Q000473:pathology*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism*
chemical_list: D051057:Proto-Oncogene Proteins c-akt
keywords: AKT; PI3K; cell biology; cell survival; human; human biology; kinase inhibitor; kinase-independent; medicine; mouse; oncogenic