title: Transfusion-Related Acute Lung Injury After IVIG for Myasthenic Crisis.
abstract: BACKGROUND
  A 26-year-old female with myasthenic crisis developed transfusion-related acute lung injury (TRALI) after she was treated with intravenous immunoglobulin.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  Respiratory status markedly worsened with each intravenous immunoglobulin (IVIG) administration and progressing from a need to use bilevel positive airway pressure (BiPAP) to intubation. Pulmonary function tests improved during this episode.
  
  
  CONCLUSIONS
  IVIG may cause TRALI and due to subtle clinical findings can be mistaken for neuromuscular respiratory failure.
authors: Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 First Street SW RO_OL_2_115CCS, Rochester, MN, 55905, USA, reddy.dereddiraja@mayo.edu.
authors: Dereddi Raja S
authors: DR
authors: Reddy
authors: Pramod K
authors: PK
authors: Guru
authors: Melissa M
authors: MM
authors: Blessing
authors: James R
authors: JR
authors: Stubbs
authors: Alejandro A
authors: AA
authors: Rabinstein
authors: Eelco F M
authors: EF
authors: Wijdicks
mesh_terms: D055371:Acute Lung Injury / Q000139:chemically induced*; D000328:Adult; D016913:Blood Component Transfusion / Q000009:adverse effects; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000009:adverse effects*; D007155:Immunologic Factors / Q000008:administration & dosage / Q000009:adverse effects*; D009157:Myasthenia Gravis / Q000188:drug therapy*
chemical_list: D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors