title: 2014 Update of the Canadian Rheumatology Association/spondyloarthritis research consortium of Canada treatment recommendations for the management of spondyloarthritis. Part I: principles of the management of spondyloarthritis in Canada.
abstract: OBJECTIVE
  The Canadian Rheumatology Association (CRA) and the Spondyloarthritis Research Consortium of Canada (SPARCC) have collaborated to update the recommendations for the management of spondyloarthritis (SpA).
  
  
  METHODS
  A working group was assembled and consisted of the SPARCC executive committee, rheumatologist leaders from SPARCC collaborating sites, Canadian rheumatologists from across the country with an interest in SpA (both academic and community), a rheumatology trainee with an interest in SpA, an epidemiologist/health services researcher, a member of the CRA executive, a member of the CRA therapeutics committee, and a patient representative from the Canadian Spondylitis Association. An extensive review was conducted of literature published from 2007 to 2014 involving the management of SpA. The working group created draft recommendations using multiple rounds of Web-based surveys and an in-person conference. A survey was sent to the membership of the CRA to obtain an extended review that was used to finalize the recommendations.
  
  
  RESULTS
  Guidelines for the management of SpA were created. Part I focuses on the principles of management of SpA in Canada and includes 6 general management principles, 5 ethical considerations, target groups for treatment recommendations, 2 wait time recommendations, and recommendations for disease monitoring. Also included are 6 modifications for application to juvenile SpA.
  
  
  CONCLUSIONS
  These recommendations were developed based on current literature and applied to a Canadian healthcare context. It is hoped that the implementation of these recommendations will promote best practices in the treatment of SpA.
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Sherry
authors: S
authors: Rohekar
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Jon
authors: J
authors: Chan
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Shirley M L
authors: SM
authors: Tse
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Nigil
authors: N
authors: Haroon
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Vinod
authors: V
authors: Chandran
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Louis
authors: L
authors: Bessette
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Dianne
authors: D
authors: Mosher
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Cathy
authors: C
authors: Flanagan
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Kevin J
authors: KJ
authors: Keen
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Karen
authors: K
authors: Adams
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Michael
authors: M
authors: Mallinson
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Carter
authors: C
authors: Thorne
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Proton
authors: P
authors: Rahman
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Dafna D
authors: DD
authors: Gladman
authors: From the University of Western Ontario, London; University of Toronto; The Hospital for Sick Children; Toronto Western Research Institute University Health Network; Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; Canadian Spondylitis Association, Toronto; Southlake Regional Health Centre, Newmarket, Ontario; University of British Columbia, Vancouver; University of North British Columbia, Prince George, British Columbia; Laval University, Quebec City, Quebec; Department of Medicine, University of Calgary, Calgary, Alberta; Memorial University, St. John's, Newfoundland, Canada.S. Rohekar, BSc, MD, FRCPC, MSc (Clin. Epi.), Associate Professor of Medicine, University of Western Ontario; J. Chan, BSc, MD, FRCPC; C. Flanagan, MDCM, Clinical Assistant Professor of Medicine, University of British Columbia; S.M. Tse, MD, FRCPC, Associate Professor of Medicine, University of Toronto, The Hospital for Sick Children; N. Haroon, MD, PhD, DM, Assistant Professor of Medicine, University of Toronto, Toronto Western Research Institute University Health Network; V. Chandran, MBBS, MD, DM, PhD, Assistant Professor of Medicine, University of Toronto, and Division of Rheumatology, Department of Medicine, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital; L. Bessette, MD, MSc, FRCPC, Assistant Professor of Medicine; K. Adams, BSc, MD, FRCPC, Associate Professor of Medicine, Laval University; D. Mosher, MD, FRCPC, Professor of Medicine, Department of Medicine, University of Calgary; K.J. Keen, PhD, PStat, PStat(ASA), Associate Professor of Mathematics and Statistics, University of North British Columbia; M. Mallinson, BA, MA, President, Canadian Spondylitis Association; C. Thorne, MD, FRCPC, Assistant Professor of Medicine, University of Toronto, Southlake Regional Health Centre; P. Rahman, MD, FRCPC, Associate Dean, Clinical Research and Professor of Medicine, Memorial Unive
authors: Robert D
authors: RD
authors: Inman
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D002170:Canada; D019468:Disease Management; D019317:Evidence-Based Medicine; D006801:Humans; D012219:Rheumatology / Q000592:standards*; D025241:Spondylarthritis / Q000188:drug therapy*
chemical_list: D018501:Antirheumatic Agents
keywords: ANKYLOSING SPONDYLITIS; PSORIATIC ARTHRITIS; SPONDYLOARTHRITIS