title: Increased number of parvovirus B19 infections in southeast Scotland in 2012-2013.
abstract: Parvovirus B19 (B19V) infections are a common but under-investigated and under-reported cause of intrauterine infections. An increased number of acute B19V infections was identified in the Edinburgh area in 2012-2013, with 123 infections diagnosed in 33 pregnant women, 76 non-pregnant women and 14 men. All except one pregnant woman were asymptomatic. An overall infection rate of 18% was measured in pregnant women who were tested following B19V exposure (26/141). Furthermore, a 7% seroconversion rate was recorded in non-immune pregnant women who were re-tested after exposure (7/104). A high fetal loss rate (25%; 3/12) was observed in those who had acute B19V infection in early pregnancy (<11 weeks) whereas all pregnancies progressed to term in those where acute infection occurred after a gestational age of 12 weeks. These results suggest that more efforts should be targeted to investigate suspected B19V infections in early pregnancy during epidemic seasons.
authors: Specialist Virology Centre, Royal Infirmary Edinburgh, UK.
authors: I
authors: I
authors: Al Shukri
authors: Specialist Virology Centre, Royal Infirmary Edinburgh, UK.
authors: F
authors: F
authors: Hamilton
authors: Clinical Pathology Services, Royal Infirmary Edinburgh, UK.
authors: M
authors: M
authors: Evans
authors: Department of Obstetrics, Royal Infirmary Edinburgh, UK.
authors: S
authors: S
authors: Cooper
authors: Public Health and Health Policy, NHS Lothian, Edinburgh, UK.
authors: G
authors: G
authors: McKenzie
authors: Public Health and Health Policy, NHS Lothian, Edinburgh, UK.
authors: L
authors: L
authors: Willocks
authors: Specialist Virology Centre, Royal Infirmary Edinburgh, UK.
authors: K
authors: K
authors: Templeton
authors: Specialist Virology Centre, Royal Infirmary Edinburgh, UK. Electronic address: heli.simmonds@hotmail.com.
authors: H
authors: H
authors: Harvala
mesh_terms: D000031:Abortion, Septic / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D058070:Asymptomatic Diseases / Q000453:epidemiology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010322:Parvoviridae Infections / Q000150:complications / Q000453:epidemiology* / Q000821:virology*; D016732:Parvovirus B19, Human / Q000302:isolation & purification*; D011247:Pregnancy; D012606:Scotland / Q000453:epidemiology; D055815:Young Adult
keywords: Antenatal screening; hydrops; miscarriage; parvovirus B19; pregnancy