title: Spinal hemangiopericytoma: an institutional experience and review of literature.
abstract: OBJECTIVE
  Hemangiopericytoma is a rare tumor of CNS with potential for recurrence and widespread metastasis, even outside CNS with even rare involvement of spinal cord. This case series presents five patients to evaluate the clinical presentation, radiological features, management, pathology and outcome of spinal hemangiopericytomas.
  
  
  METHODS
  Between 2004 and 2013, five patients underwent surgery for spinal hemangiopericytoma. Histopathological data were reviewed in all cases and clinical and follow-up details were collected from the data available in our department.
  
  
  RESULTS
  There were three males and two females, including one pediatric patient. Three patients had dorsal spine involvement and two patients had involvement of cervical spine. There were two patients with intradural extramedullary tumors, one patient each with pure intramedullary tumor, pure extradural tumor and both intra and extradural tumor. All of them presented with motor weakness. Gross total resection of the tumor was done in three patients. Four patients received post-operative radiotherapy. Histopathology showed anaplastic tumor in four cases with high MIB-1 LI. Most of them were positive for CD34, mic-2 and bcl-2. Three patients who underwent gross total resection improved significantly in the follow-up period. Two patients who underwent subtotal resection expired due to spread of their disease.
  
  
  CONCLUSIONS
  Spinal hemangiopericytoma is a rare tumor. Strong clinical suspicion is required to diagnose it pre-operatively. Gross total resection is the goal and radiotherapy should be given in case of residual tumor or high-grade tumors.
authors: Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.
authors: Amitabha
authors: A
authors: Das
authors: Pankaj Kumar
authors: PK
authors: Singh
authors: Vaishali
authors: V
authors: Suri
authors: Mukund N
authors: MN
authors: Sable
authors: Bhawani Shankar
authors: BS
authors: Sharma
mesh_terms: D000328:Adult; D002574:Cervical Vertebrae; D002648:Child; D005260:Female; D006393:Hemangiopericytoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery