title: Low vitamin D intake is associated with increase in cardiovascular risk factors in obese adolescents.
abstract: OBJECTIVE
  This study aimed to investigate the effect of vitamin D on cardiovascular risk in obese adolescents.
  
  
  METHODS
  Thirty (16 females/14 males) post-puberty obese adolescents (15-19 years) were involved and measurements of inflammatory biomarkers, body composition, visceral fat, and vitamin D (serum and intake) were performed. The adolescents were submitted to a long-term interdisciplinary therapy with physical exercise, nutritional, psychological, and clinical interventions.
  
  
  RESULTS
  Negative correlations between vitamin D intake with plasminogen activator inhibitor-1 (PAI-1) (r=-0.69; p=0.01) and vascular cell adhesion molecule (VCAM-1) (r=-0.82; p=0.001) were found in the population analyzed. Improvement in PAI-1, VCAM-1, body composition, and visceral fat, were observed.
  
  
  CONCLUSIONS
  We showed that low vitamin D intake is associated with an increase in the cardiovascular risk factors in obese adolescents.
authors: R M
authors: RM
authors: Campos
authors: D C
authors: DC
authors: Masquio
authors: F C
authors: FC
authors: Corgosinho
authors: J P
authors: JP
authors: Carvalho-Ferreira
authors: B D
authors: BD
authors: Netto
authors: C
authors: C
authors: Ackel-D'Elia
authors: L
authors: L
authors: Tock
authors: S
authors: S
authors: Tufik
authors: M T
authors: MT
authors: de Mello
authors: A R
authors: AR
authors: Damaso
mesh_terms: D000293:Adolescent; D000328:Adult; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000517:prevention & control; D003131:Combined Modality Therapy; D004435:Eating / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D063766:Pediatric Obesity / Q000097:blood / Q000453:epidemiology*; D012307:Risk Factors; D014807:Vitamin D / Q000008:administration & dosage* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000453:epidemiology*; D061217:Weight Reduction Programs; D055815:Young Adult
chemical_list: D014807:Vitamin D