title: No Superiority of High-Flexion vs Standard Total Knee Arthroplasty: An Update Meta-Analysis of Randomized Controlled Trials.
abstract: This meta-analysis was performed using a Cochrane systematic review approach to examine published data with an aim to clarify whether standard or high flexion prostheses increase the range of knee motion and clinical outcomes. 1778 patients from 17 randomized controlled trials were identified. No significant differences in the range of motion, weight-bearing flexion and hip functions scores were found between treatment groups. We also found no significant differences in complications with regard to revision, component loosening, deep infection, anterior knee pain, stiffness, post-operative bone fracture and post-operative patella clunk syndrome, but the high flexion prostheses group had a higher incidence of deep venous thrombosis. The results do not support the proposition that high flexion knee prostheses provide substantial clinical advantages over standard knee prostheses.
authors: Department of Sports Medicine, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi, P.R. China.
authors: Yong
authors: Y
authors: Jiang
authors: Department of joint surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi, P.R. China.
authors: Jian Feng
authors: JF
authors: Yao
authors: Institute of Endemic Diseases, Key Laboratory of Environment and Genes Related to Diseases of Education Ministry, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, P.R. China.
authors: Yong Min
authors: YM
authors: Xiong
authors: Department of joint surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi, P.R. China.
authors: Jian Bing
authors: JB
authors: Ma
authors: Department of Sports Medicine, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi, P.R. China.
authors: Hui
authors: H
authors: Kang
authors: Department of joint surgery, Hong Hui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi, P.R. China.
authors: Peng
authors: P
authors: Xu
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects / Q000295:instrumentation*; D006801:Humans; D015994:Incidence; D007719:Knee Joint / Q000502:physiology / Q000601:surgery; D007720:Knee Prosthesis / Q000009:adverse effects / Q000706:statistics & numerical data*; D011183:Postoperative Complications / Q000453:epidemiology; D011184:Postoperative Period; D011474:Prosthesis Design; D016032:Randomized Controlled Trials as Topic; D016059:Range of Motion, Articular; D012086:Reoperation; D020246:Venous Thrombosis / Q000453:epidemiology; D016474:Weight-Bearing
keywords: high flexion; meta-analysis; ramdomized controlled trial; total knee arthroplasty; treatment outcome