title: Access to medications and conducting clinical trials in LMICs.
abstract: Access to essential medications is limited in many low-to-middle income countries (LMICs) and those that are available may be prohibitively expensive to the general population. Clinical trials have been suggested as an approach to improve drug access in LMICs but the number of trials conducted in these countries is small because of regulatory issues and a lack of infrastructure. In this article, Nature Reviews Nephrology asks three experts their opinions on how to improve drug access and increase the numbers of clinical trials conducted in LMICs.
authors: Division of Nephrology and Hypertension, Department of Medicine, Groote Schuur Hospital and University of Cape Town, Observatory 7925, Cape Town, South Africa.
authors: Ikechi G
authors: IG
authors: Okpechi
authors: Division of Nephrology and Hypertension, Department of Medicine, Groote Schuur Hospital and University of Cape Town, Observatory 7925, Cape Town, South Africa.
authors: Charles R
authors: CR
authors: Swanepoel
authors: Wits Reproductive Health and HIV Institute, University of the Witwatersrand, PO Box 2616, Saxonwold 2132, South Africa.
authors: Francois
authors: F
authors: Venter
mesh_terms: D002986:Clinical Trials as Topic; D003906:Developing Countries; D006297:Health Services Accessibility / Q000706:statistics & numerical data; D006801:Humans; D011203:Poverty; D055553:Prescription Drugs / Q000600:supply & distribution*
chemical_list: D055553:Prescription Drugs