title: Comparison of long-term quality of life of pediatric burn survivors with and without inhalation injury.
abstract: OBJECTIVE
  To examine the long-term quality of life of pediatric burn survivors with and without inhalation injuries. We hypothesized that patients with inhalation injury would report more disability and lower quality of life.
  
  
  METHODS
  We examined 51 patients with inhalation injury and 72 without inhalation injury who had burns of ≥10% total body surface area, were age ≥16 years at time of the interview, and were greater than 5 years from injury. Subjects completed the World Health Organization Disability Assessment Scale II (WHODAS II) and the Burn Specific Health Scale-Brief (BSHS-B). Multiple regression analyses were used to measure the effects of inhalation injury while controlling for age at burn and TBSA.
  
  
  RESULTS
  The mean age of burn of participants with inhalation injury was 11.7±3.6 years, mean TBSA 55%±18, and mean ventilator days 8.4±9. The mean age of burn of participants without inhalation injury was 10.3±34.1 years, mean TBSA 45%±20, and mean ventilator days 1.3±5.2. Inhalation injury did not appear to significantly impact participants' scores on the majority of the domains. The WHODAS II domain of household activities showed a significant relation with TBSA (p=0.01). Increased size of burn was associated with difficulty completing tasks for both groups. The BSHS-B domain of treatment regimen showed a relation with age at burn (p=0.02). Increased age was associated difficulty in this area for both groups.
  
  
  CONCLUSIONS
  Overall the groups were comparable in their reports of disability and quality of life. Inhalation injury did not affect long-term quality of life.
authors: Shriners Hospitals for Children, Galveston, TX 77550, United States; University of Texas Medical Branch, Galveston, TX 77555, United States. Electronic address: marosenb@utmb.edu.
authors: Marta
authors: M
authors: Rosenberg
authors: Shriners Hospitals for Children, Galveston, TX 77550, United States; University of Texas Medical Branch, Galveston, TX 77555, United States.
authors: Maribel
authors: M
authors: Ramirez
authors: Shriners Hospitals for Children, Galveston, TX 77550, United States; University of Texas Medical Branch, Galveston, TX 77555, United States.
authors: Kathy
authors: K
authors: Epperson
authors: Shriners Hospitals for Children, Galveston, TX 77550, United States; University of Texas Medical Branch, Galveston, TX 77555, United States.
authors: Lisa
authors: L
authors: Richardson
authors: Shriners Hospitals for Children, Galveston, TX 77550, United States; University of Texas Medical Branch, Galveston, TX 77555, United States.
authors: Charles
authors: C
authors: Holzer
authors: Shriners Hospitals for Children, Galveston, TX 77550, United States; University of Texas Medical Branch, Galveston, TX 77555, United States.
authors: Clark R
authors: CR
authors: Andersen
authors: Shriners Hospitals for Children, Galveston, TX 77550, United States; University of Texas Medical Branch, Galveston, TX 77555, United States.
authors: David N
authors: DN
authors: Herndon
authors: Shriners Hospitals for Children, Galveston, TX 77550, United States; University of Texas Medical Branch, Galveston, TX 77555, United States.
authors: Walter
authors: W
authors: Meyer
authors: Shriners Hospitals for Children, Galveston, TX 77550, United States; University of Texas Medical Branch, Galveston, TX 77555, United States.
authors: Oscar E
authors: OE
authors: Suman
authors: Shriners Hospitals for Children, Galveston, TX 77550, United States; University of Texas Medical Branch, Galveston, TX 77555, United States.
authors: Ronald
authors: R
authors: Mlcak
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D001830:Body Surface Area; D002056:Burns / Q000503:physiopathology / Q000523:psychology* / Q000628:therapy; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006304:Health Status; D006801:Humans; D007902:Length of Stay; D016014:Linear Models; D008137:Longitudinal Studies; D008297:Male; D051346:Mobility Limitation; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology*; D012121:Respiration, Artificial; D015208:Smoke Inhalation Injury / Q000503:physiopathology / Q000523:psychology* / Q000628:therapy; D012917:Social Adjustment; D058992:Social Participation; D017741:Survivors / Q000523:psychology*; D055815:Young Adult
keywords: Inhalation injury; Long term; Outcome adolescents; Psychosocial; Quality of life