title: [Clinical, microbiological and evolutionary profile of patients experiencing failures and relapses of tuberculosis in Ivory Coast].
abstract: BACKGROUND
  Multidrug-resistant tuberculosis (MDR-TB) is a major obsession for TB control. The main risk factor for MDR-TB remains a history of TB treatment especially bad conduct. The objective of this study is to describe the profile of patients in situations of failure and relapse of tuberculosis.
  
  
  METHODS
  We performed a retrospective survey of the analysis of records of patients starting TB retreatment for failure or relapse of tuberculosis. We used 193 cases with results of culture-sensitivity.
  
  
  RESULTS
  The proportion of failure is 59/193 (30.6 %) and cases of relapse are 134/193 (69.4 %). The proportion of married life is 23.4 % (11/47) in chess against 41.5 % (51/123) in relapse of TB [P=0.021, OR=0.431 (0.201 to 0.927)]. Patients failing therapy have more chest pain [5.8 % (3/52) versus 0 % (0/126) with P=0.024]. The proportion of MDR-TB was 61.4 (38/59) in case of failure against 41 % (55/134) in case of relapse [P=0.002, OR=2.599 (1.378 to 4.902)]. The evolution is the same whatever the indication of reprocessing.
  
  
  CONCLUSIONS
  The proportion of MDR-TB is very important in case of reprocessing failure and relapse of tuberculosis.
authors: Centre antituberculeux, Yopougon, Côte d'Ivoire. Electronic address: raissantakpe@yahoo.fr.
authors: N
authors: N
authors: Kouamé-N'Takpé
authors: Service de pneumologie, CHU de Cocody, Abidjan, Côte d'Ivoire.
authors: K
authors: K
authors: Horo
authors: Service de pneumologie, CHU de Cocody, Abidjan, Côte d'Ivoire.
authors: A
authors: A
authors: Koné
authors: Unité de mycobactérie, Institut Pasteur, Abidjan, Côte d'Ivoire.
authors: K R
authors: KR
authors: N'guessan
authors: Centre antituberculeux, Adjamé, Côte d'Ivoire.
authors: K
authors: K
authors: Touré
authors: Service de pneumologie, CHU de Cocody, Abidjan, Côte d'Ivoire.
authors: C
authors: C
authors: Kouadio
authors: Centre antituberculeux, Adjamé, Côte d'Ivoire.
authors: D
authors: D
authors: Assi
authors: Centre antituberculeux, Yopougon, Côte d'Ivoire.
authors: I
authors: I
authors: Coulibaly
authors: Programme national de lutte contre la tuberculose, Abidjan, Côte d'Ivoire.
authors: A
authors: A
authors: Kouakou
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use*; D002648:Child; D007560:Cote d'Ivoire / Q000453:epidemiology; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D017211:Treatment Failure; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents
keywords: Failure; Multi-résistance; Multidrug-resistant; Rechute; Relapse; Tuberculose; Tuberculosis; Échec