title: Survival in South Asian and White European patients after acute myocardial infarction.
abstract: OBJECTIVE
  To examine the association between ethnicity and survival following acute myocardial infarction (AMI) in White European (WE) and South Asian (SA) patients from a multiethnic UK population.
  
  
  METHODS
  Retrospective, cohort study of 4111 (N=730, 17.8% of SA ethnicity) hospitalised patients, with AMI from a tertiary coronary care centre in the UK, admitted between October 2002 and September 2008. The primary end point was all-cause mortality. The association of ethnicity with survival post AMI was assessed using the Cox regression analysis.
  
  
  RESULTS
  Compared with WE patients, SA patients were on average younger (62.0 years vs 67.3 years) and had higher prevalence of cardiovascular risk factors including diabetes (39.7% vs 16.1%). During follow-up (median 912, range 1-2556, days), crude mortality rate was 22.6% in SA patients and 26.0% in WE patients (p = 0.061). SA ethnicity did not show univariate (HR 0.85 (0.72 to 1.01)) or multivariate (HR, 1.12 (0.94 to 1.34)) association with mortality. Findings were similar for mortality during 0-30 days (1.30 (0.99 to 1.70)), > 30 days-1 year (0.97 (0.67 to 1.40)), > 1 year-3 years (1.21 (0.83 to 1.76)), > 3 years (0.82 (0.47 to 1.41)), and for long-term mortality in survivors from 30 days (1.02 (0.81 to 1.29)).
  
  
  CONCLUSIONS
  When adjusted for differing prevalence of cardiovascular risk factors in the two ethnic groups, survival following AMI was similar for SA and WE patients in the UK.
authors: Diabetes Research Centre, University of Leicester, Leicester, UK Department of Diabetes and Endocrinology, and Department of Acute Medicine, University Hospitals Coventry and Warwickshire, Coventry, UK.
authors: Nitin N
authors: NN
authors: Gholap
authors: Diabetes Research Centre, University of Leicester, Leicester, UK Leicester Clinical Trials Unit, University of Leicester, Leicester Diabetes Centre, Leicester, UK NIHR Collaborations for Leadership in Applied Health Research and Care (CLAHRC), Leicester, UK.
authors: Kamlesh
authors: K
authors: Khunti
authors: Leicester Clinical Trials Unit, University of Leicester, Leicester Diabetes Centre, Leicester, UK Lifestyle & Physical Activity Biomedical Research Unit, Leicester-Loughborough NIHR Diet, Leicester, UK.
authors: Melanie J
authors: MJ
authors: Davies
authors: Diabetes Research Centre, University of Leicester, Leicester, UK Leicester Clinical Trials Unit, University of Leicester, Leicester Diabetes Centre, Leicester, UK.
authors: Danielle H
authors: DH
authors: Bodicoat
authors: Department of Cardiovascular Sciences, University of Leicester, Leicester, UK Leicester NIHR Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK.
authors: Iain B
authors: IB
authors: Squire
mesh_terms: D000368:Aged; D044466:Asian People; D002423:Cause of Death / Q000639:trends; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000208:ethnology / Q000401:mortality*; D015995:Prevalence; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D015996:Survival Rate / Q000639:trends; D006113:United Kingdom / Q000453:epidemiology; D044465:White People