title: c-Fos protein expression in the anterior amygdaloid area and nc. accumbens in the hypoxic rat brain.
abstract: BACKGROUND
  By examining the production of c-Fos protein, we analyzed the response to the ischemic attack in different brain tissue, two of which are regions of the limbic system: the anterior amygdaloid area and nc. accumbens.
  
  
  METHODS
  We used the model of rat brain ischemia--four-vessel occlusion, and Pulsinelli's method. The rats were treated in two ways, according to which they were divided into two groups: a total ischemia (ligation of four blood vessels, i.e. electrocauterization of the vertebral artery with bilateral ligation of the carotid artery--the so-called R-group rats), and transient ischemic attack (ligation of four blood vessels, i.e. electrocauterization of the vertebral artery, with mutual re-ligation of the carotid arteries in the form of transient ischemia--the so-called T-group rats, which can also be called "pre-conditioned group"). Both groups had their own control group.
  
  
  CONCLUSIONS
  We have concluded that parts of the brain with an important role for the survival have a strong expression of c-fos gene.
authors: Siniša S
authors: SS
authors: Babović
authors: Sonja
authors: S
authors: Žigić
authors: Branislav
authors: B
authors: Šakić
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000378:metabolism; D066276:Corticomedial Nuclear Complex / Q000378:metabolism*; D002534:Hypoxia, Brain / Q000378:metabolism*; D002546:Ischemic Attack, Transient / Q000378:metabolism*; D008297:Male; D009714:Nucleus Accumbens / Q000378:metabolism*; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism*; D017208:Rats, Wistar
chemical_list: D016760:Proto-Oncogene Proteins c-fos