title: Blood and urine 8-iso-PGF2α levels in babies of different gestational ages.
abstract: OBJECTIVE
  We measured cord blood and urine 8-iso-prostaglandin F2α (8-iso-PGF2α) levels in babies of different gestational ages to determine lipid peroxidation status.
  
  
  METHODS
  Babies at gestational ages of 28-43 weeks were divided into group A (28-32 weeks), group B (33-36 weeks), group C (37-41 weeks), and group D (42-43 weeks). 8-iso-PGF2α in umbilical cord blood (UCB) at birth and urine at 6 hours after birth was and tested by ELISA.
  
  
  RESULTS
  UCB and urine 8-iso-PGF2α levels in group C were 130.09 ± 31.73 pg/ml and 27.14 ± 6.73 pg/ml, respectively. UCB 8-iso-PGF2α levels in group A and B were 188.42 ± 59.34 pg/ml and 189.37 ± 68.46 pg/ml, and urine 8-iso-PGF2α were 32.14 ± 7.32 pg/ml and 30.46 ± 8.83 pg/ml, respectively. Blood and urine 8-iso-PGF2α levels in group D (post-term) were 252.01 ± 46.42 pg/ml and 44.00 ± 8.50 pg/ml. For all babies, UCB and urine iso-PGF2α levels were significantly correlated (r = 0.65, P < 0.01).
  
  
  CONCLUSIONS
  We established blood and urine iso-PGF2α levels in normal full-term babies. Urine 8-iso-PGF2α levels may reflect the extent of lipid peroxidation in babies. In pre-term and post-term babies, there was evidence for increased lipid peroxidation.
authors: Department of Neonatology, The Sixth Affiliated Hospital of Sun Yat-Sen University Guangzhou 510655, China.
authors: Sitao
authors: S
authors: Li
authors: Department of Neonatology, The Sixth Affiliated Hospital of Sun Yat-Sen University Guangzhou 510655, China.
authors: Hu
authors: H
authors: Hao
authors: Department of Neonatology, Baoan Women and Children Hospital Shenzhen 518103, China.
authors: Ping
authors: P
authors: Zhou
authors: Department of Neonatology, Foshan Women and Children Hospital Foshan 52800, China.
authors: Ping Ming
authors: PM
authors: Gao
authors: Department of Neonatology, The Sixth Affiliated Hospital of Sun Yat-Sen University Guangzhou 510655, China.
authors: Xin
authors: X
authors: Xiao
keywords: 8-iso-prostaglandin F2α; Babies; cord blood; lipid peroxidation; urine