title: Case of intraperitoneal sepsis secondary to rupture of the appendix on the background of pseudomyxoma peritonei.
abstract: BACKGROUND
  Pseudomyxoma peritonei (PMP) is characterised by gelatinous ascites and pools of mucin associated with neoplastic mucinous epithelium within the peritoneal cavity. It can rarely present as acute intraperitoneal sepsis, requiring urgent medical attention.
  
  
  METHODS
  A 59-year old male was referred to our centre in February 2014 following a diagnostic laparotomy, which showed jelly-like material with occasional epithelial cells. He was listed for peritonectomy in a month's time at our centre. Three weeks later, he was admitted urgently to our hospital due to generalised abdominal pain and watery diarrhoea. Examination at admission was unremarkable. On the following day, he became haemodynamically unstable and was suspected to have intraperitoneal sepsis due to infected PMP. At emergency laparotomy, we found gross intraperitoneal sepsis and did extensive debulking of tumour, appendectomy and extensive division of adhesions. Another laparotomy was done 24 h later for washout. He was discharged three weeks after.
  
  
  CONCLUSIONS
  Although we have done 780 peritonectomy procedures, this was the first patient with this presentation of widerspread intraperitoneal sepsis. Continuous mucous production of appendiceal adenoma can lead to appendiceal rupture. The appendix may decompress by perforation and then reseal. However, one episode of appendiceal rupture can cause bacterial contamination of PMP, leading to sepsis.
  
  
  CONCLUSIONS
  Intraperitoneal sepsis secondary to appendiceal rupture is rare. Hence surgeons may face an emergency of intraperitoneal sepsis during waiting period of planned CRS or as a primary presentation. With combined therapy of CRS and PIC, the prognosis of mucinous appendiceal adenoma is excellent.
authors: Department of Surgery, St George Hospital, The University of New South Wales, Sydney, NSW 2217, Australia.
authors: Y
authors: Y
authors: Huang
authors: Department of Surgery, St George Hospital, The University of New South Wales, Sydney, NSW 2217, Australia.
authors: N A
authors: NA
authors: Alzahrani
authors: Department of Surgery, St George Hospital, The University of New South Wales, Sydney, NSW 2217, Australia.
authors: W
authors: W
authors: Liauw
authors: Department of Surgery, St George Hospital, The University of New South Wales, Sydney, NSW 2217, Australia.
authors: D L
authors: DL
authors: Morris
keywords: Appendiceal mucinous adenoma; Intraperitoneal sepsis; Pseudomyxoma peritonei