title: Two new flavones from Salvia plebeia.
abstract: Two new flavones neocafhispidulin (1) and 6″-O-acetyl homoplantaginin (2), together with 10 known flavones and 1 polyphenol were isolated from the whole plants of Salvia plebeia. R. Br. Compounds 3 and 4 were reported from this plant for the first time. Their structures were determined by spectral analyses. Compounds 1-13 were evaluated for their anti-tyrosinase and anti-inflammatory activities. The results showed that compounds 1, 5, 8, 10 and 11 exhibited anti-tyrosinase activities, and compounds 3, 4 and 13 showed potential anti-inflammatory activities.
authors: a Key Laboratory of Standardization of Chinese Medicines, Ministry of Education, Institute of Chinese Materia Medica of Shanghai University of Traditional Chinese Medicine , Cai Lun Road 1200, Zhangjiang , Shanghai 201203 , P.R. China.
authors: Min-Rong
authors: MR
authors: Jin
authors: Hong
authors: H
authors: Xu
authors: Chao-Hui
authors: CH
authors: Duan
authors: Gui-Xin
authors: GX
authors: Chou
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000302:isolation & purification; D002460:Cell Line; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000302:isolation & purification; D047309:Flavones / Q000737:chemistry* / Q000302:isolation & purification; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D015394:Molecular Structure; D014442:Monophenol Monooxygenase / Q000037:antagonists & inhibitors; D027544:Salvia / Q000737:chemistry*
chemical_list: C000601242:6''-O-acetylhomoplantaginin; D000893:Anti-Inflammatory Agents; D004791:Enzyme Inhibitors; D047309:Flavones; C000601241:neocafhispidulin; D014442:Monophenol Monooxygenase
keywords: Salvia plebeian; anti-inflammatory; anti-tyrosinase; flavones