title: Minimizing antibiotic exposure in the ICU: in search of the optimal strategy.
abstract: The current paradigm for antibiotic management in critically ill patients is to initiate broad-spectrum therapy followed by de-escalation based on microbiological results. Routine screening cultures may allow better targeting and reduce unnecessary exposure to antibiotics.
authors: Christian
authors: C
authors: Brun-Buisson
mesh_terms: D000465:Algorithms; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D003428:Cross Infection / Q000188:drug therapy*; D062665:Epidemiological Monitoring; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D018410:Pneumonia, Bacterial / Q000188:drug therapy*; D053717:Pneumonia, Ventilator-Associated / Q000188:drug therapy*
chemical_list: D000890:Anti-Infective Agents