title: Treating seizures in Creutzfeldt-Jakob disease.
abstract: Seizures are known to occur in Creutzfeldt-Jakob disease (CJD). In the setting of a rapidly progressive condition with no effective therapy, determining appropriate treatment for seizures can be difficult if clinical morbidity is not obvious yet the electroencephalogram (EEG) demonstrates a worrisome pattern such as status epilepticus. Herein, we present the case of a 39-year-old man with CJD and electrographic seizures, discuss how this case challenges conventional definitions of seizures, and discuss a rational approach toward treatment. Coincidentally, our case is the first report of CJD in a patient with Stickler syndrome.
authors: Epilepsy Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
authors: Marcus C
authors: MC
authors: Ng
authors: Epilepsy Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
authors: M Brandon
authors: MB
authors: Westover
authors: Epilepsy Service, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
authors: Andrew J
authors: AJ
authors: Cole
keywords: Creutzfeldt–Jakob disease; Epilepsy; Seizures; Status epilepticus; Stickler syndrome