title: Changes in caries risk and activity of a 9-year-old patient with niemann-pick disease type C.
abstract: Objective. This case report describes the changes in caries risk and activity and dental treatment of a 9-year-old patient who presented with signs and symptoms of Niemann-Pick disease type C (NPC). Treatment. The preventive dental treatment included instructions to caregivers for oral hygiene and diet. A calcium hydroxide pulpotomy and restorative dental treatments were performed in a dental office with desensitization techniques and behavioral management. The patient was attended every 3 months for the control of dental plaque biofilm, for topical fluoride application, and for observing the pulpotomized tooth. Results. The bacterial plaque biofilm was being adequately controlled by the caregiver. After 2 years, the clinical and radiographic examination of the pulpotomized tooth showed the absence of internal root resorption and bone rarefaction, and clinical examination showed tooth sensitivity, dental pain, and gingival swelling. Conclusion. The pulpotomy prevented clinical and radiographic success. Dentists must be aware of and be able to identify systemic and local aspects associated with caries risk of children with NPC disease. Furthermore, dentists must employ stringent preventive measures and provide instructions to caregivers to reduce caries risk.
authors: Department of Pediatric Clinics Dentistry, Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Monte Alegre, 14040-904 Ribeirão Preto, SP, Brazil.
authors: Késsia Suênia Fidelis
authors: KS
authors: Mesquita-Guimarães
authors: Department of Pediatric Clinics Dentistry, Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Monte Alegre, 14040-904 Ribeirão Preto, SP, Brazil.
authors: Andiara
authors: A
authors: De Rossi
authors: Department of Pediatric Clinics Dentistry, Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Monte Alegre, 14040-904 Ribeirão Preto, SP, Brazil.
authors: Aldevina Campos
authors: AC
authors: Freitas
authors: Department of Pediatric Clinics Dentistry, Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Monte Alegre, 14040-904 Ribeirão Preto, SP, Brazil.
authors: Paulo
authors: P
authors: Nelson-Filho
authors: Department of Pediatric Clinics Dentistry, Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Monte Alegre, 14040-904 Ribeirão Preto, SP, Brazil.
authors: Raquel Assed
authors: RA
authors: da Silva
authors: Department of Pediatric Clinics Dentistry, Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Monte Alegre, 14040-904 Ribeirão Preto, SP, Brazil.
authors: Alexandra Mussolino
authors: AM
authors: de Queiroz