title: Behçet's disease and comorbidity: internal case reports and literature review.
abstract: The aim of this study was to determine the clinical characteristics of two patients with malignancy related to Behçet's disease. We reviewed literary-reported cases of Behçet's disease related to myelodysplastic syndrome, neoplasm and leukemia. Our own observation included two cases of comorbid conditions of Behçet's disease. The first patient with Behçet's disease had been examined concurrent development of intestinal tumor. The second one was diagnosed to have chromic myeloleukemia. The malignant transformation of Behçet's disease patients, both solid and hematological, is rather rare. Further accumulation of relevant date and its analysis will allow to find out the relationship between malignant disease and chemotherapy in Behçet's disease.
authors: Nasonova Research Institute of Rheumatology, Moscow, Russia.
authors: Zemfira
authors: Z
authors: Alekberova
authors: Nasonova Research Institute of Rheumatology, Moscow, Russia.
authors: Vadim
authors: V
authors: Gorodetskiy
authors: Nasonova Research Institute of Rheumatology, Moscow, Russia. f.izmailova@yandex.ru.
authors: Fatima
authors: F
authors: Izmailova
authors: Nasonova Research Institute of Rheumatology, Moscow, Russia.
authors: Stefka
authors: S
authors: Radenska-Lopovok
authors: Nasonova Research Institute of Rheumatology, Moscow, Russia.
authors: Elnura
authors: E
authors: Talybova
authors: Nasonova Research Institute of Rheumatology, Moscow, Russia.
authors: Margarita
authors: M
authors: Evsikova
authors: State Budgetary Health-Care Agency, Municipal Clinical Hospital, No. 7, Moscow Health-Care Department, Moscow, Russia.
authors: Nikolai
authors: N
authors: Timoshin
authors: Nasonova Research Institute of Rheumatology, Moscow, Russia.
authors: Evgeni
authors: E
authors: Nasonov
mesh_terms: D000230:Adenocarcinoma / Q000150:complications*; D000293:Adolescent; D000328:Adult; D001528:Behcet Syndrome / Q000150:complications*; D003110:Colonic Neoplasms / Q000150:complications*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications*; D008297:Male; D008875:Middle Aged; D055815:Young Adult
keywords: Behçet’s disease; Comorbidity; Myelodysplastic syndrome