title: New insights into genes, immunity, and the occurrence of dermatophytosis.
abstract: Fungal infections in humans are among the most prevalent diseases globally. Superficial invasion by dermatophytes leads to skin, hair, and nail infection. Even though they have usually been associated with extrinsic conditions such as immunosuppression, environmental factors, and contaminated individuals, objects, or surfaces; people are not equally susceptible to dermatophyte infection, even when they have the same risk factors. This commentary summarizes findings that provide evidence of familial or genetic predisposition to fungal infection, mediated by innate and/or adaptive immunity.
authors: Department of Dermatology, National Institute of Pediatrics, Mexico City, Mexico. Electronic address: teregarro@gmail.com.
authors: Maria T
authors: MT
authors: García-Romero
authors: Section of Mycology, Hospital General Dr. Manuel Gea González, Mexico City, Mexico.
authors: Roberto
authors: R
authors: Arenas
mesh_terms: D005260:Female; D018628:Gene Dosage / Q000235:genetics*; D006801:Humans; D007378:Interleukins / Q000097:blood*; D008297:Male; D014005:Tinea / Q000097:blood* / Q000235:genetics*; D023083:beta-Defensins / Q000097:blood* / Q000235:genetics*; D000097043:Interleukin-22
chemical_list: D007378:Interleukins; D023083:beta-Defensins; D000097043:Interleukin-22; C106641:DEFB4A protein, human