title: Synthesis of Vinyl Trifluoromethyl Thioethers via Copper-Mediated Trifluoromethylthiolation of Vinyl Bromides.
abstract: A copper-mediated trifluoromethylthiolation of vinyl bromides has been developed. This method provides ready access to vinyl trifluoromethyl thioethers in good to high yields from simple, inexpensive starting materials. A broad substrate scope is achieved, and the reaction is compatible with various functional groups, including cyano, nitro, trifluoromethyl, alkoxy, amino, halide, and heterocyclic groups.
authors: Department of Chemistry, Fuzhou University , Fuzhou, Fujian 350108, P. R. China.
authors: Yangjie
authors: Y
authors: Huang
authors: Jianping
authors: J
authors: Ding
authors: Chuyi
authors: C
authors: Wu
authors: Huidong
authors: H
authors: Zheng
authors: Zhiqiang
authors: Z
authors: Weng
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006219:Halogens / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D009570:Nitriles / Q000737:chemistry*; D013440:Sulfides / Q000138:chemical synthesis* / Q000737:chemistry; D014753:Vinyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D006219:Halogens; D006571:Heterocyclic Compounds; D006845:Hydrocarbons, Fluorinated; D009570:Nitriles; D013440:Sulfides; D014753:Vinyl Compounds; D003300:Copper; C003763:vinyl bromide