title: Metachronous metastatic paraganglioma in jejunum as a rare entity: A case report.
abstract: Pheochromocytomas and paragangliomas are neuroendocrine tumors that arise from chromaffin cells of adrenal medulla and extra-adrenal paraganglia, respectively. The recurrence of these neuroendocrine tumors as a jejunal mass causing obstruction in the small intestine is an exceptional entity. The present study reports the case of a 70-year-old male who presented to the Emergency Department of Bezmialem Vakif University Hospital with abdominal pain and vomiting. The patient possessed a history of left nephrectomy due to malignant pheochromocytoma that had invaded into the left kidney eight months prior to presentation. Bowel obstruction was diagnosed and the patient underwent a laparoscopic procedure. Partial resection of the jejunum was performed and immunohistochemical studies revealed the lesion to be malignant paraganglioma. The majority of paragangliomas are chemo- and radioresistant. Surgical excision remains the primary treatment. Metachronous paraganglioma arising from the small intestine is an extremely rare entity and may be a relevant consideration in patients presenting with bowel obstruction.
authors: Department of General Surgery, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, Turkey.
authors: Huseyin Kazim
authors: HK
authors: Bektasoglu
authors: Department of General Surgery, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, Turkey.
authors: Gokhan
authors: G
authors: Cipe
authors: Department of General Surgery, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, Turkey.
authors: Erkan
authors: E
authors: Yardimci
authors: Department of Pathology, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, Turkey.
authors: Dilek Sema
authors: DS
authors: Arici
authors: Department of General Surgery, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, Turkey.
authors: Mustafa
authors: M
authors: Hasbahceci
authors: Department of General Surgery, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, Turkey.
authors: Oguzhan
authors: O
authors: Karatepe
authors: Department of General Surgery, Faculty of Medicine, Bezmialem Vakif University, Istanbul 34093, Turkey.
authors: Mahmut
authors: M
authors: Muslumanoglu
keywords: bowel obstruction; jejunum; paraganglioma; pheochromocytoma