title: [Cancer control in focus insights and future perspectives for the focal treatment of prostate cancer].
abstract: Faced with the dilemma of choosing between the extremes of standard whole gland therapy and active surveillance, those affected by prostate cancer have recently been on the lookout for less invasive alternatives. Particularly the question of whether it would be possible in low risk cancer to treat only the tumour itself while sparing the organ has long been considered. This article discusses the pros and cons of focal treatment and elucidates the latest innovative technologies. High overtreatment rates in low-risk patients submitted to standard therapy and considerable technological advances in diagnosis (particularly multiparametric MRI) and therapy are regarded by the authors as key arguments for abandoning complete tumour eradication with its side effects in favour of sufficient local cancer control by focal treatment with better preserved quality of life in suitable cases.
authors: Klinik für Urologie und Kinderurologie, Universitätsklinikum Magdeburg.
authors: M
authors: M
authors: Schostak
authors: MVZ Hanse Histologikum, Schwerpunkt Uropathologie, Hamburg.
authors: J
authors: J
authors: Köllermann
authors: Urologische Klinik und Poliklinik, Ruprecht-Karls-Universität Heidelberg.
authors: B
authors: B
authors: Hadaschik
authors: Klinik für Urologie und Kinderurologie, Klinikum Fürth.
authors: A
authors: A
authors: Blana
authors: Urologische Klinik und Poliklinik der Universität Leipzig.
authors: R
authors: R
authors: Ganzer
authors: Urologische Praxis Dr. Henkel & Dr. Kahmann, Berlin.
authors: T
authors: T
authors: Henkel
authors: Klinik für Urologie, Theresienkrankenhaus Mannheim.
authors: K U
authors: KU
authors: Köhrmann
authors: Klinik für Urologie und Kinderurologie, Universitätsklinikum Magdeburg.
authors: U-B
authors: UB
authors: Liehr
authors: Klinik für Urologie, Marienkrankenhaus Bergisch-Gladbach.
authors: S
authors: S
authors: Machtens
authors: Urologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, Klinikum Großhadern, München.
authors: A
authors: A
authors: Roosen
authors: Martini-Klinik am UKE GmbH, Hamburg.
authors: G
authors: G
authors: Salomon
authors: Urologische Gemeinschaftspraxis, Sinsheim.
authors: L
authors: L
authors: Sentker
authors: Klinik für Urologie und Kinderurologie, Krankenhaus Nordwest, Frankfurt/Main.
authors: U
authors: U
authors: Witzsch
authors: Abteilung für Radiologie des Deutschen Krebsforschungszentrums Heidelberg.
authors: H-P
authors: HP
authors: Schlemmer
authors: Klinik für Urologie und Kinderurologie, Universitätsklinikum Magdeburg.
authors: D
authors: D
authors: Baumunk
mesh_terms: D001706:Biopsy; D018450:Disease Progression; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D008297:Male; D000069342:Medical Overuse; D060787:Neoplasm Grading; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis; D011467:Prostate / Q000473:pathology; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome