title: Determining Health-Related Quality-of-Life Outcomes Using the SF-6D Preference-Based Measure in Patients Following Total Knee Arthroplasty.
abstract: The SF-6D, a health-related quality-of-life measure, assigns value to patients' perception of their health. We determined SF-6D values of 844 TKA patients, deduced clinical relevance of value changes using effect size, and compared these to clinical and functional improvements 6weeks, 3months, and 1 through 5years post-operatively. The SF-6D significantly improved at all follow-ups after 6weeks. The effect size indicated clinical relevance at every follow-up. The KSS improved at all follow-ups (+43, +51, +56, +57, +57 points), and LEAS scores improved at follow-ups after 6weeks (+1 point at 3months, +2 points thereafter), correlating with SF-6D changes. Deducing utility scores facilitates cost analyses, allowing clinicians to deduce quality-adjusted life-years and economic impacts of treatments.
authors: Rubin Institute for Advanced Orthopedics, Center for Joint Preservation and Replacement, Sinai Hospital of Baltimore, Baltimore, Maryland.
authors: Randa K
authors: RK
authors: Elmallah
authors: Rubin Institute for Advanced Orthopedics, Center for Joint Preservation and Replacement, Sinai Hospital of Baltimore, Baltimore, Maryland.
authors: Jeffrey J
authors: JJ
authors: Cherian
authors: Rubin Institute for Advanced Orthopedics, Center for Joint Preservation and Replacement, Sinai Hospital of Baltimore, Baltimore, Maryland.
authors: Julio J
authors: JJ
authors: Jauregui
authors: Stryker Orthopaedic, Mahwah, New Jersey.
authors: Manoshi
authors: M
authors: Bhowmik-Stoker
authors: OrthoCarolina Hip and Knee Center, Charlotte, North Carolina.
authors: Walter B
authors: WB
authors: Beaver
authors: Rubin Institute for Advanced Orthopedics, Center for Joint Preservation and Replacement, Sinai Hospital of Baltimore, Baltimore, Maryland.
authors: Michael A
authors: MA
authors: Mont
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000191:economics; D015992:Body Mass Index; D016208:Databases, Factual; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000191:economics / Q000523:psychology*; D057240:Patient Preference; D011184:Postoperative Period; D011788:Quality of Life; D019057:Quality-Adjusted Life Years; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
keywords: SF-6D; health-related measure; outcomes; quality of life; total knee arthroplasty