title: Ruthenium catalyzed synthesis of 2,3-unsaturated C-glycosides from glycals.
abstract: A highly efficient and convenient C-glycosylation method was developed using ruthenium(III) chloride for the synthesis of 2,3-unsaturated C-glycosides. Various nucleophiles such as allyl trimethylsilane, triethylsilane, trimethylsilyl cyanide, trimethylsilyl azide and heterocycles such as thiophene and furan reacted smoothly with glycals in the presence of catalytic amount of ruthenium trichloride under mild reaction conditions.
authors: D-207, Discovery Laboratory, Organic and Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India.
authors: Batthula
authors: B
authors: Srinivas
authors: D-207, Discovery Laboratory, Organic and Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India.
authors: Thurpu Raghavender
authors: TR
authors: Reddy
authors: D-207, Discovery Laboratory, Organic and Biomolecular Chemistry Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India. Electronic address: skashyap@iict.res.in.
authors: Sudhir
authors: S
authors: Kashyap
mesh_terms: D002384:Catalysis; D006027:Glycosides / Q000138:chemical synthesis*; D006031:Glycosylation; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D006027:Glycosides; D012428:Ruthenium
keywords: C-glycosides; Ferrier glycosylation; Glycal; Ruthenium trichloride; Stereoselective synthesis