title: Preparation and characterization of aqueous dispersions of dextrin and policosanol composites.
abstract: Policosanol (50-100mg) was dispersed in an aqueous solution (0.5-2.0% solids, w/v, 50 mL) of an amylomaize starch dextrin at 90°C under different conditions. The dispersion of the mixture was opaque but remained homogenous for up to 7 days at an ambient temperature. The precipitates obtained by centrifuging the dispersion (5,000 × g, 30 min) contained crystalline V-amylose complex of policosanol. The supernatant also contained policosanol but not in the complex form. Stepwise addition of policosanol and longer time complex formation increased the dispersible policosanol: about 95% by 30 min interval, 1.0% dextrin solution and 12h complex formation time. Among the dispersible policosanol (95%), 70% policosanol resided in the precipitates and 25% was in the supernatant, indicating the dextrin behaved as a stabilizer for the dispersed policosanol as well as a complex forming agent with policosanol. The policosanol dispersion was sonicated up to 30s to evaluate physical stability. Around 70% policosanol in the dispersion remained stable against the sonication treatment.
authors: Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, Republic of Korea.
authors: Jong-Yea
authors: JY
authors: Kim
authors: School of Life Sciences and Biotechnology, Korea University, 5-1, Anam-dong, Sungbuk-ku, Seoul 136-701, Republic of Korea.
authors: Ju Hun
authors: JH
authors: Lee
authors: School of Life Sciences and Biotechnology, Korea University, 5-1, Anam-dong, Sungbuk-ku, Seoul 136-701, Republic of Korea.
authors: Du-Yun
authors: DY
authors: Jeong
authors: Samyang Genex Co. R&D Center, 305-707 Daejeon, Republic of Korea.
authors: Dong-Kyun
authors: DK
authors: Jang
authors: School of Life Sciences and Biotechnology, Korea University, 5-1, Anam-dong, Sungbuk-ku, Seoul 136-701, Republic of Korea.
authors: Tae-Rang
authors: TR
authors: Seo
authors: School of Life Sciences and Biotechnology, Korea University, 5-1, Anam-dong, Sungbuk-ku, Seoul 136-701, Republic of Korea. Electronic address: limst@korea.ac.kr.
authors: Seung-Taik
authors: ST
authors: Lim
mesh_terms: D003912:Dextrins / Q000737:chemistry*; D005233:Fatty Alcohols / Q000737:chemistry*; D013010:Sonication; D013213:Starch / Q000737:chemistry; D013696:Temperature; D013997:Time Factors; D014867:Water / Q000737:chemistry*
chemical_list: D003912:Dextrins; D005233:Fatty Alcohols; D014867:Water; C080710:policosanol; C013862:caloreen; D013213:Starch
keywords: Aqueous dispersion; Dextrin; Inclusion complex; Policosanol; V-amylose