title: Metal-ligand cooperation by aromatization-dearomatization as a tool in single bond activation.
abstract: Metal-ligand cooperation (MLC) plays an important role in bond activation processes, enabling many chemical and biological catalytic reactions. A recent new mode of activation of chemical bonds involves ligand aromatization-dearomatization processes in pyridine-based pincer complexes in which chemical bonds are broken reversibly across the metal centre and the pincer-ligand arm, leading to new bond-making and -breaking processes, and new catalysis. In this short review, such processes are briefly exemplified in the activation of C-H, H-H, O-H, N-H and B-H bonds, and mechanistic insight is provided. This new bond activation mode has led to the development of various catalytic reactions, mainly based on alcohols and amines, and to a stepwise approach to thermal H2 and light-induced O2 liberation from water.
authors: Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot 76100, Israel david.milstein@weizmann.ac.il.
authors: David
authors: D
authors: Milstein
mesh_terms: D001895:Boron / Q000737:chemistry; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D002621:Chemistry / Q000379:methods*; D006859:Hydrogen / Q000737:chemistry; D007495:Iridium / Q000737:chemistry; D008024:Ligands; D008670:Metals / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D008024:Ligands; D008670:Metals; D014867:Water; D007495:Iridium; D002244:Carbon; D006859:Hydrogen; D009584:Nitrogen; D001895:Boron
keywords: B–H activation; C–H activation; N–H activation; O–H activation; catalysis; metal–ligand cooperation