title: Validation of the OMERACT Magnetic Resonance Imaging Joint Space Narrowing Score for the Wrist in a Multireader Longitudinal Trial.
abstract: OBJECTIVE
  To assess the intrareader and interreader agreement and sensitivity to change of the Outcome Measures in Rheumatology (OMERACT) Rheumatoid Arthritis Magnetic Resonance Imaging Joint Space Narrowing (RAMRIS-JSN) score in the rheumatoid arthritis (RA) wrist in a longitudinal multireader exercise.
  
  
  METHODS
  Coronal T1-weighted MR image sets of 1 wrist from 20 patients with early RA were assessed twice for JSN at 17 sites at baseline and after 36 or 60 months by 4 readers blinded to patient data but not time order. The joints were scored 0-4 according to the OMERACT RAMRIS-JSN score. Intraclass correlation coefficients (ICC), smallest detectable change (SDC), percentage exact/close agreement (PEA/PCA), and standardized response mean (SRM) were calculated.
  
  
  RESULTS
  Median baseline and change score was 10.3 and 1.9, respectively. Intrareader ICC for baseline and change scores was good (≥ 0.50) to very good (≥ 0.80) for all and 3 of 4 readers, respectively. Interreader ICC was very good for change (0.93), while poor for baseline score if all 4 readers were included (0.36), but very good if 1 reader was excluded (0.87). Intrareader and interreader SDC was low (2.34-3.18), except for the intrareader SDC for 1 reader (6.75). The mean PEA/PCA was high for baseline and change scores both within and between the readers (51.5-99.2), except for interreader baseline PEA (14.4). SRM was moderate for all readers (0.55-0.77).
  
  
  CONCLUSIONS
  The OMERACT RAMRIS-JSN score showed high overall intrareader and interreader reliability, and moderate sensitivity to change, supporting inclusion of the measure as part of the OMERACT RAMRIS system.
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Daniel
authors: D
authors: Glinatsi
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Siri
authors: S
authors: Lillegraven
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Espen A
authors: EA
authors: Haavardsholm
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Iris
authors: I
authors: Eshed
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Philip G
authors: PG
authors: Conaghan
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Charles
authors: C
authors: Peterfy
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Frédérique
authors: F
authors: Gandjbakhch
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Paul
authors: P
authors: Bird
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Pernille
authors: P
authors: Bøyesen
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Uffe M
authors: UM
authors: Døhn
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Harry K
authors: HK
authors: Genant
authors: From the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo, Oslo, Norway; Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, UK; Spire Sciences Inc., Boca Raton, Florida, USA; Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC, Paris, France; University of New South Wales, Sydney, Australia; Medicine and Orthopedics, University of California, San Francisco, and Synarc Inc., San Francisco, California, USA.D. Glinatsi, MD, Research Fellow, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, University of Copenhagen; S. Lillegraven, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital, University of Oslo; E.A. Haavardsholm, MD, PhD, Postdoctoral Researcher, Department of Rheumatology, Diakonhjemmet Hospital; I. Eshed, MD, Professor of Radiology, Sheba Medical Center; P.G. Conaghan, MB, BS, PhD, FRACP, FRCP, Professor of Musculoskeletal Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit; C. Peterfy, MD, PhD, FRCP, Chief Executive Officer, Spire Sciences Inc.; F. Gandjbakhch, MD, Practicing Rheumatologist, Department of Rheumatology, Pitié Salpêtrière Hospital, APHP, Université Paris 6-UPMC; P. Bird, BMed (Hons), FRACP, PhD, Grad Dip MRI, Senior Lecturer, University of New South Wales; P. Bøyesen, MD, PhD, Department of Rheumatology, Diakonhjemmet Hospital; U.M. Døhn, MD, PhD, Copenhagen Center for Arthritis Research, Center for Rhe
authors: Mikkel
authors: M
authors: Østergaard
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000175:diagnosis*; D015331:Cohort Studies; D032921:Consensus; D003718:Denmark; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D014955:Wrist Joint / Q000473:pathology*
keywords: JOINT SPACE NARROWING; MAGNETIC RESONANCE IMAGING; OMERACT; RAMRIS; RHEUMATOID ARTHRITIS