title: Extensive carcinoma cuniculatum of the mandible.
abstract: Carcinoma cuniculatum (CC) is a rare variant of squamous cell carcinoma first described in 1954. Cases of CC in the head and neck are exceedingly rare, with 66 cases reported since 1977. These tumors are generally low-grade, well-differentiated and locally aggressive malignancies. Patients are often subjected to a long period of misdiagnoses given the clinical similarity of these entities to odontogenic cysts and abscesses. We report a case of a carcinoma cuniculatum of the mandible with very advanced local involvement of disease, highlighting the unusual characteristics of this rare tumor that are important for clinicians to recognize. Clinical presentation, histology, risk factors, treatment options, and prognosis are also reviewed.
authors: University of California Los Angeles, Department of Head and Neck Surgery, 10833 Le Conte Ave, CHS 62-142, Los Angeles, CA. Electronic address: sshay@mednet.ucla.edu.
authors: Sophie
authors: S
authors: Shay
authors: David Geffen School of Medicine, 10833 Le Conte Ave, CHS 62-142, Los Angeles, CA. Electronic address: wchoy@mednet.ucla.edu.
authors: Winward
authors: W
authors: Choy
authors: University of California Los Angeles, School of Dentistry, 714 Tiverton Ave, Los Angeles, CA. Electronic address: rchristensen@dentistry.ucla.edu.
authors: Russell E
authors: RE
authors: Christensen
authors: University of California Los Angeles, Department of Head and Neck Surgery, 10833 Le Conte Ave, CHS 62-142, Los Angeles, CA; University of California Los Angeles, Jonsson Comprehensive Cancer Center, 8-684 Factor Building, Box 951781, Los Angeles, CA; UCLA Head and Neck Cancer Program, University of California Los Angeles, Los Angeles, CA. Electronic address: mstjohn@mednet.ucla.edu.
authors: Maie A
authors: MA
authors: St John
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D008875:Middle Aged