title: Adult-onset temporal lobe epilepsy, cognitive decline, multi-antiepileptic drug hypersensitivity, and Hashimoto's encephalopathy: Two case studies.
abstract: Hashimoto's encephalopathy is defined by the coexistence of encephalopathy and antithyroid antibodies. We report two cases of adult-onset temporal lobe epilepsy with subacute cognitive decline, high titers of antithyroid antibodies, multi-antiepileptic drug hypersensitivity, and good response to immunomodulatory treatment. The relevance of multidrug hypersensitivity in the setting of adult-onset epilepsy and the importance of searching for autoimmune causes for epilepsy are discussed.
authors: Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
authors: Ofer
authors: O
authors: Sadan
authors: Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
authors: Estelle
authors: E
authors: Seyman
authors: Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
authors: Elissa L
authors: EL
authors: Ash
authors: Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel ; Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors: Svetlana
authors: S
authors: Kipervasser
authors: Department of Neurology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel ; Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors: Miri Y
authors: MY
authors: Neufeld
keywords: AED; Hashimoto's encephalopathy; Hypersensitivity; Temporal lobe epilepsy