title: Solitary intraosseous schwannoma of the base and vault of the skull: a summary review of such unusual location.
abstract: Intra-osseous schwannoma is a rare mesenchymal tumor. Although, the head and neck region is one of the most common sites for schwannomas, its location at the skull bone is uncommon and accounted for less than 0.2% in the largest series of bone tumors ever reported. Furthermore, it is most often a benign tumor, malignant transformation is exceedingly rare. Clinical presentation is non-specific, most often symptoms are associated with compression and invasion of adjacent organs. Neuro-imaging features are non-specific and the diagnosis is based on histological examination with immunohistochemical study. Surgery remains the aim of treatment. However, radiation therapy could be an interesting therapeutic option in unresectable tumors. This systemic review offers new clinicopathological data useful for better defining the diagnosis and clinicopathological behavior of schwannoma. The purpose of this work is to raise awareness among clinicians adding this clinical entity as a differential diagnosis when a mass of skull bone is identified.
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Fadoua
authors: F
authors: Rais
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Naoual
authors: N
authors: Benhmidou
authors: Department of Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Ghizlane
authors: G
authors: Rais
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Fadila
authors: F
authors: Kouhen
authors: Department of Oncology, National Institute of Oncology, Rabat, Morocco.
authors: Khadija
authors: K
authors: Bellahamou
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Hasna
authors: H
authors: Loughlimi
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Abdelhak
authors: A
authors: Maghous
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Sanae
authors: S
authors: Elmejjaoui
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Hanan
authors: H
authors: Elkacemi
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Tayeb
authors: T
authors: Kebdani
authors: Department of Radiotherapy, National Institute of Oncology, Rabat, Morocco.
authors: Noureddine
authors: N
authors: Benjaafar
keywords: Intra-osseous schwannoma; Schwannoma; Skull bone