title: [Prefabrication of heart valves].
abstract: BACKGROUND
  Commonly used heart valve prostheses have specific drawbacks and limitations.
  
  
  OBJECTIVE
  Optimization of conventional methods and techniques for heart valve replacement by application of tissue engineering principles.
  
  
  CONCLUSIONS
  Recent studies have impressively shown that allogeneic decellularized matrices have the potential to overcome limitations of conventional prostheses and to provide all the characteristics of an ideal graft for heart valve replacement.
authors: Klinik für Herz-, Thorax-, Transplantation- und Gefäßchirurgie, Medizinische Hochschule Hannover, Carl Neuberg Str. 1, 30625, Hannover, Deutschland.
authors: T
authors: T
authors: Goecke
authors: I
authors: I
authors: Tudorache
authors: A
authors: A
authors: Hilfiker
authors: A
authors: A
authors: Haverich
authors: S
authors: S
authors: Cebotari
mesh_terms: D062088:Acellular Dermis; D006349:Heart Valve Diseases / Q000601:surgery*; D006350:Heart Valve Prosthesis; D006351:Heart Valves / Q000601:surgery*; D006801:Humans; D011475:Prosthesis Failure; D023822:Tissue Engineering / Q000379:methods*