title: Corneal collagen cross-linking in keratoconus -- long-term prospective study.
abstract: OBJECTIVE
  To determine the refractometric, keratometric and functional results 3 years after cross-linking therapy in patients with keratoconus.
  
  
  METHODS
  Eighty-one patients in various stages of keratoconus were studied, all meeting eligibility criteria for the cross-linking technique.
  
  
  RESULTS
  The results showed a decrease both in the K-values, of about 1.5 D, and in the refraction. Visual acuity improved by 1, 2 or 3 Snellen lines in 70% of the cases.
  
  
  CONCLUSIONS
  The cross-linking technique is a modern method for stopping the progression of keratoconus.
authors: Optilens Clinic, 137, 21 Decembrie street, Cluj-Napoca, Romania. Electronic address: niculacristina65@yahoo.com.
authors: C
authors: C
authors: Nicula
authors: Optilens Clinic, 137, 21 Decembrie street, Cluj-Napoca, Romania.
authors: D
authors: D
authors: Nicula
authors: Optilens Clinic, 137, 21 Decembrie street, Cluj-Napoca, Romania.
authors: R
authors: R
authors: Popescu
authors: Faculty of general medicine, "Iuliu Haţieganu" university of medicine and pharmacy, 8, Victor Babeş street, Cluj-Napoca, Romania.
authors: A
authors: A
authors: Saplonţai-Pop
mesh_terms: D000293:Adolescent; D000328:Adult; D003094:Collagen / Q000378:metabolism*; D003319:Corneal Stroma / Q000187:drug effects / Q000378:metabolism*; D003432:Cross-Linking Reagents / Q000627:therapeutic use*; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007640:Keratoconus / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D058105:Polymerization; D011446:Prospective Studies; D012029:Refraction, Ocular / Q000187:drug effects; D012256:Riboflavin / Q000627:therapeutic use; D014467:Ultraviolet Therapy; D014792:Visual Acuity / Q000187:drug effects; D055815:Young Adult
chemical_list: D003432:Cross-Linking Reagents; D003094:Collagen; D012256:Riboflavin
keywords: Collagène cornéen; Corneal collagen; Cross-linking technique; Cross-linking therapy; Keratoconus; Kératocône; Refractometry; Réfractométrie