title: Application and evaluation of a molecular approach for detection of the schistosomicidal effect of Mirazid® (myrrh) in the murine model.
abstract: The conventional PCR technique was used for studying the schistosomicidal effect of Mirazid® in the murine model. Results of the molecular study were compared with the parasitological results (ova and worm count). The used PCR technique was more sensitive than the Kato-Katz thick smears. Mirazid® showed some schistosomicidal effects against murine Schistosoma mansoni. However, it was not efficient enough to cure any of the studied mice.
authors: Parasitology Department, Medical Research Institute, Alexandria University, Egypt.
authors: Wael M
authors: WM
authors: Lotfy
authors: Department of Applied Medical Chemistry, Medical Research Institute, Alexandria University, Egypt.
authors: Aly M
authors: AM
authors: Nageh
authors: Department of Applied Medical Chemistry, Medical Research Institute, Alexandria University, Egypt.
authors: Neveen A
authors: NA
authors: Hussein
authors: Department of Applied Medical Chemistry, Medical Research Institute, Alexandria University, Egypt ; Department of Laboratory Sciences, Faculty of Health Sciences, Jazan University, Saudi Arabia.
authors: Ashraf A
authors: AA
authors: Hassan
keywords: Antischistosomal; Diagnosis; Mirazid; Murine; PCR; Schistosoma mansoni; Treatment