title: Sonochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles using nanocrystalline MgAl2O4 as an effective catalyst.
abstract: An efficient four-component synthesis of 1,2,4,5-tetrasubstituted imidazoles is described by one-step condensation of an aldehyde, benzil, ammonium acetate and primary aromatic amine with nanocrystalline magnesium aluminate in ethanol under ultrasonic irradiation. High yields, short reaction times, mild conditions, simplicity of operation and easy work-up are some advantages of this protocol.
authors: Laboratory of Organic Chemistry Research, Department of Chemistry, Faculty of Chemistry, University of Kashan, P. O. Box 87317-51167, Kashan, Iran.
authors: Javad
authors: J
authors: Safari
authors: Laboratory of Organic Chemistry Research, Department of Chemistry, Faculty of Chemistry, University of Kashan, P. O. Box 87317-51167, Kashan, Iran.
authors: Soheila
authors: S
authors: Gandomi-Ravandi
authors: Laboratory of Organic Chemistry Research, Department of Chemistry, Faculty of Chemistry, University of Kashan, P. O. Box 87317-51167, Kashan, Iran.
authors: Zahra
authors: Z
authors: Akbari
keywords: Four-component reaction; Imidazole; One-pot synthesis; Ultrasonic irradiation