title: Epithelioid angiosarcoma of the ilium: a case report.
abstract: Bone epithelioid angiosarcoma (EA) is rare and characterized by large, mildly to moderately pleomorphic epithelioid cells, with abundant eosinophilic cytoplasm, vesicular nuclei, and prominent nucleoli. The tumors may arise in various locations in bone and the patients may present with unifocal or multifocal osseous disease. We present a unifocal lesion case of EA of the ilium in a 62-year-old woman. A needle biopsy of the ilium was performed and first diagnosed poorly differentiated adenocarcinoma based on CKpan and CK18 immunopositivity. The tumor was treated initially with curettage followed by chemotherapy. The final diagnosis on the surgical specimen was epithelioid angiosarcoma.
authors: Department of Pathology, Qian-Fo-Shan Hospital Affiliated Shandong University 16766 Jingshi Road, Jinan 250014, China ; Department of Pathology, Yatai Yaitaishan Hospital 91 Jiefang Road, Yatai 264001, China.
authors: Mingxia
authors: M
authors: Chen
authors: Department of Pathology, Yatai Yaitaishan Hospital 91 Jiefang Road, Yatai 264001, China.
authors: Wei
authors: W
authors: Zhang
authors: Department of Pathology, Yatai Yaitaishan Hospital 91 Jiefang Road, Yatai 264001, China.
authors: Jianli
authors: J
authors: Qu
authors: Department of Pathology, Yatai Yaitaishan Hospital 91 Jiefang Road, Yatai 264001, China.
authors: Lei
authors: L
authors: Li
authors: Department of Pathology, Qian-Fo-Shan Hospital Affiliated Shandong University 16766 Jingshi Road, Jinan 250014, China.
authors: Qing
authors: Q
authors: Sun
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D001859:Bone Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D003475:Curettage; D003951:Diagnostic Errors; D015622:Epithelioid Cells / Q000737:chemistry / Q000187:drug effects / Q000473:pathology*; D005260:Female; D006394:Hemangiosarcoma / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007085:Ilium / Q000737:chemistry / Q000187:drug effects / Q000473:pathology* / Q000601:surgery; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor
keywords: Epithelioid angiosarcoma; bone