title: Advances in the mechanisms and early warning indicators of the postoperative cognitive dysfunction after the extracorporeal circulation.
abstract: The high incidence of postoperative cognitive dysfunction (POCD) after extracorporeal circulation has seriously affected the prognosis and quality of life. Its mechanism may involve the inflammatory response and oxidative stress,the excessive phosphorylation of tau protein, the decreased blood volume and oxygen in the cerebral cortex. Appropriate early warning indicators of POCD after the extracorporeal circulation should be chosen to facilitate the cross validation of the results obtained different technical approaches and thus promote the early diagnosis and treatment of POCD.
authors: Department of Anesthesiology, Tianjin Chest Hospital, Tianjin 300222, China.
authors: Chao
authors: C
authors: Liu
authors: Department of Anesthesiology, Tianjin Chest Hospital, Tianjin 300222, China.
authors: Jian-ge
authors: JG
authors: Han
mesh_terms: D002540:Cerebral Cortex; D003071:Cognition; D003072:Cognition Disorders; D005112:Extracorporeal Circulation; D006801:Humans; D018384:Oxidative Stress; D010100:Oxygen; D010766:Phosphorylation; D011183:Postoperative Complications; D011379:Prognosis; D011788:Quality of Life; D016875:tau Proteins
chemical_list: D016875:tau Proteins; D010100:Oxygen