title: Noninvasive physiologic assessment of coronary stenoses using cardiac CT.
abstract: Coronary CT angiography (CCTA) has become an important noninvasive imaging modality in the diagnosis of coronary artery disease (CAD). CCTA enables accurate evaluation of coronary artery stenosis. However, CCTA provides limited information on the physiological significance of stenotic lesions. A noninvasive "one-stop-shop" diagnostic test that can provide both anatomical significance and functional significance of stenotic lesions would be beneficial in the diagnosis and management of CAD. Recently, with the introduction of novel techniques, such as myocardial CT perfusion, CT-derived fractional flow reserve (FFRCT), and transluminal attenuation gradient (TAG), CCTA has emerged as a noninvasive method for the assessment of both anatomy of coronary lesions and its physiological consequences during a single study. This review provides an overview of the current status of new CT techniques for the physiologic assessments of CAD.
authors: Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.
authors: Lei
authors: 0000-0002-8499-0448
authors: L
authors: Xu
authors: Discipline of Medical Imaging, Department of Imaging and Applied Physics, Curtin University, Perth, WA 6845, Australia.
authors: Zhonghua
authors: 0000-0002-7538-4761
authors: Z
authors: Sun
authors: Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.
authors: Zhanming
authors: Z
authors: Fan
mesh_terms: D017023:Coronary Angiography / Q000379:methods*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging*; D006801:Humans