title: [Electrophoretic mobility and activity Na,K-ATPase of erytheocytes in rats under stress].
abstract: In this paper, we study the relation between the electrophoretic mobility of erythrocytes (EPME) and the activity of Na,K-ATPase of erythrocytes under the action of different types of stress factors (immobilization, hypoxia, radiation exposure), as well as the introduction of stress implementing agents (adrenaline, cortisol, bee and toad venom) rats. Activity of Na,K-ATPase and the change of EPME washed erythrocytes were examined through 15, 120 min and 24 hours after exposure. Found that at the initial stage (15 min after a stress-exposure) decrease of EPME associated with increased enzyme activity and further increase of EPME takes place on the background of the decrease of activity of Na,K-ATPase in all types of alterations, except the actions toad venom and cortisol. Toad venom and cortisol led to reduced activity of Na,K-ATPase and increase of EPME.
authors: V N
authors: VN
authors: Krylov
authors: A V
authors: AV
authors: Deriugina
authors: A I
authors: AI
authors: Konstantinova
mesh_terms: D000664:Amphibian Venoms / Q000494:pharmacology; D000818:Animals; D021461:Animals, Outbred Strains; D001514:Bee Venoms / Q000494:pharmacology; D002478:Cells, Cultured; D004586:Electrophoresis; D004837:Epinephrine / Q000494:pharmacology; D004912:Erythrocytes / Q000166:cytology* / Q000187:drug effects / Q000201:enzymology / Q000528:radiation effects; D005260:Female; D005720:Gamma Rays; D006854:Hydrocortisone / Q000494:pharmacology; D000860:Hypoxia / Q000201:enzymology* / Q000503:physiopathology; D007103:Immobilization; D010100:Oxygen / Q000494:pharmacology; D051381:Rats; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013312:Stress, Physiological / Q000187:drug effects / Q000528:radiation effects; D013997:Time Factors
chemical_list: D000664:Amphibian Venoms; D001514:Bee Venoms; D000254:Sodium-Potassium-Exchanging ATPase; D010100:Oxygen; D006854:Hydrocortisone; D004837:Epinephrine