title: Nanocarriers in therapy of infectious and inflammatory diseases.
abstract: Nanotechnology is a growing science that has applications in various areas of medicine. The composition of nanocarriers for drug delivery is critical to guarantee high therapeutic performance when targeting specific host sites. Applications of nanotechnology are prevalent in the diagnosis and treatment of infectious and inflammatory diseases. This review summarizes recent advancements in the application of nanotechnology to the therapy of infectious and inflammatory diseases. The major focus is on the design and fabrication of various nanomaterials, characteristics and physicochemical properties of drug-loaded nanocarriers, and the use of these nanoscale drug delivery systems in treating infectious and inflammatory diseases, such as AIDS, hepatitis, tuberculosis, melanoma, and representative inflammatory diseases. Clinical trials and future perspective of the use of nanocarriers are also discussed in detail. We hope that such a review will be valuable to researchers who are exploring nanoscale drug delivery systems for the treatment of specific infectious and inflammatory diseases.
authors: Department of Chemical and Biological Engineering, Iowa State University, Ames, IA 50011, USA. qunwang@iastate.edu.
authors: Ufuoma
authors: U
authors: Ikoba
authors: Haisheng
authors: H
authors: Peng
authors: Haichun
authors: H
authors: Li
authors: Cathy
authors: C
authors: Miller
authors: Chenxu
authors: C
authors: Yu
authors: Qun
authors: Q
authors: Wang
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000818:Animals; D004337:Drug Carriers / Q000494:pharmacology*; D006505:Hepatitis / Q000188:drug therapy*; D006801:Humans; D007239:Infections / Q000188:drug therapy*; D007249:Inflammation / Q000188:drug therapy; D008545:Melanoma / Q000188:drug therapy*; D053758:Nanoparticles
chemical_list: D004337:Drug Carriers