title: Wavelet-based characterization of gait signal for neurological abnormalities.
abstract: Studies conducted by the World Health Organization (WHO) indicate that over one billion suffer from neurological disorders worldwide, and lack of efficient diagnosis procedures affects their therapeutic interventions. Characterizing certain pathologies of motor control for facilitating their diagnosis can be useful in quantitatively monitoring disease progression and efficient treatment planning. As a suitable directive, we introduce a wavelet-based scheme for effective characterization of gait associated with certain neurological disorders. In addition, since the data were recorded from a dynamic process, this work also investigates the need for gait signal re-sampling prior to identification of signal markers in the presence of pathologies. To benefit automated discrimination of gait data, certain characteristic features are extracted from the wavelet-transformed signals. The performance of the proposed approach was evaluated using a database consisting of 15 Parkinson's disease (PD), 20 Huntington's disease (HD), 13 Amyotrophic lateral sclerosis (ALS) and 16 healthy control subjects, and an average classification accuracy of 85% is achieved using an unbiased cross-validation strategy. The obtained results demonstrate the potential of the proposed methodology for computer-aided diagnosis and automatic characterization of certain neurological disorders.
authors: E.N.S. de l'Energie, l'Eau et l'Environnement, Laboratoire de Traitement du signal, de l'image et d'automatique, France. Electronic address: elisabeth.baratin@gmail.com.
authors: E
authors: E
authors: Baratin
authors: Department of Electrical and Computer Engineering, Ryerson University, Canada. Electronic address: lsugavan@ee.ryerson.ca.
authors: L
authors: L
authors: Sugavaneswaran
authors: Department of Electrical and Computer Engineering, Ryerson University, Canada. Electronic address: karthi@ee.ryerson.ca.
authors: K
authors: K
authors: Umapathy
authors: E.N.S. de l'Energie, l'Eau et l'Environnement, Laboratoire de Traitement du signal, de l'image et d'automatique, France. Electronic address: Cornel.Ioana@gipsa-lab.grenoble-inp.fr.
authors: C
authors: C
authors: Ioana
authors: Department of Electrical and Computer Engineering, Ryerson University, Canada. Electronic address: krishnan@ee.ryerson.ca.
authors: S
authors: S
authors: Krishnan
mesh_terms: D000328:Adult; D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000175:diagnosis / Q000503:physiopathology*; D016208:Databases, Factual; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D005260:Female; D005684:Gait / Q000502:physiology*; D006801:Humans; D006816:Huntington Disease / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000175:diagnosis / Q000503:physiopathology*; D058067:Wavelet Analysis; D055815:Young Adult
keywords: Automated diagnosis; Gait; Neurological disorders; Non-uniform sampling; Wavelet decomposition