title: Obesity and vitamin D deficiency: a systematic review and meta-analysis.
abstract: Over the past decade, there have been an increasing number of studies on the association between vitamin D deficiency and anthropometric state. However, we did not identify any meta-analyses of the relationship between obesity and vitamin D deficiency in different age groups. Thus, we evaluated the association between obesity and vitamin D deficiency. We searched for observational studies published up to April 2014 in PubMed/Medline, Web of Science and Scopus databases. We performed a meta-analysis in accordance with the random-effects model to obtain the summary measurement (prevalence ratio, PR). Among the 29,882 articles identified, 23 met the inclusion criteria. The prevalence of vitamin D deficiency was 35% higher in obese subjects compared to the eutrophic group (PR: 1.35; 95% CI: 1.21-1.50) and 24% higher than in the overweight group (PR: 1.24; 95% CI: 1.14-1.34). These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.
authors: Instituto de Saúde Coletiva, Federal University of Bahia, Salvador, Bahia, Brazil; School of Nutrition, Federal University of Bahia, Salvador, Bahia, Brazil.
authors: M
authors: M
authors: Pereira-Santos
authors: P R F
authors: PR
authors: Costa
authors: A M O
authors: AM
authors: Assis
authors: C A S T
authors: CA
authors: Santos
authors: D B
authors: DB
authors: Santos
mesh_terms: D017677:Age Distribution; D006801:Humans; D009765:Obesity / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D015995:Prevalence; D014807:Vitamin D / Q000031:analogs & derivatives; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications* / Q000453:epidemiology
chemical_list: D014807:Vitamin D
keywords: 25-hydroxy vitamin D; meta-analysis; obesity; vitamin D deficiency