title: Clinical and functional outcomes in people with schizophrenia with a high sense of well-being.
abstract: Optimal outcome in schizophrenia is thought to include remission of symptoms, functional recovery, and improved subjective well-being. The present study examined the characteristics of individuals with schizophrenia who report being satisfied with their life in general. Individuals with schizophrenia who participated in the Clinical Antipsychotic Trial of Intervention Effectiveness study were included in the present analysis. Approximately half of the individuals evaluated reported a high level of life satisfaction, even while many concurrently described themselves as at least moderately ill and experiencing moderate-severe symptoms and manifested severe functional deficits. Of all individuals evaluated, only about 1% experienced what was considered to be optimal outcome. Individuals with schizophrenia are able to experience a high level of life satisfaction, despite experiencing severe illness and functional deficits. Those involved in care should be aware that life satisfaction as an outcome is not necessarily associated with symptom remission and superior functioning.
authors: *Schizophrenia Division, Centre for Addiction and Mental Health; and †Institute of Medical Science and ‡Department of Psychiatry, University of Toronto, Toronto, Canada.
authors: Gagan
authors: G
authors: Fervaha
authors: Ofer
authors: O
authors: Agid
authors: Hiroyoshi
authors: H
authors: Takeuchi
authors: George
authors: G
authors: Foussias
authors: Jimmy
authors: J
authors: Lee
authors: Gary
authors: G
authors: Remington
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D010549:Personal Satisfaction; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D012074:Remission Induction; D012559:Schizophrenia / Q000503:physiopathology / Q000628:therapy*; D012565:Schizophrenic Psychology