title: Siderochelins with anti-mycobacterial activity from Amycolatopsis sp. LZ149.
abstract: Three new compounds, namely siderochelins D (2), E (3), and F (4), together with one known siderochelin A (1), were isolated from Amycolatopsis sp. LZ149 and elucidated by spectroscopic analyses including1D- and 2D-NMR and X-ray single crystal diffraction. Compounds 1-3 showed antibacterial activity against Mycobacterium smegmatis.
authors: Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China. Electronic address: ahua0966@sdu.edu.cn.
authors: Chun-Hua
authors: CH
authors: Lu
authors: School of Life Sciences, Xiamen University, Xiamen 361005, china.
authors: Fang-Wen
authors: FW
authors: Ye
authors: Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China; School of Life Sciences, Xiamen University, Xiamen 361005, china.
authors: Yue-Mao
authors: YM
authors: Shen
mesh_terms: D039903:Actinobacteria / Q000737:chemistry*; D000890:Anti-Infective Agents / Q000494:pharmacology*; D004095:Dihydropyridines / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D020102:Mycobacterium smegmatis / Q000187:drug effects*
chemical_list: D000890:Anti-Infective Agents; D004095:Dihydropyridines; C031982:siderochelin A
keywords: Amycolatopsis sp. LZ149; Bioassay-guided; Mycobacterium smegmatis; Siderochelin; X-ray single crystal diffraction