title: Leveraging comparative effectiveness research to improve the quality of multidisciplinary care for breast cancer patients.
abstract: Breast cancer is the most commonly diagnosed cancer among women. To date, the use of efficacy randomized controlled trials (RCTs) in breast cancer have resulted in dramatic improvements in oncologic outcomes for this disease. However, not every question pertinent to breast cancer is amenable to such efficacy trials. This chapter will discuss some of the unique aspects of breast cancer that make efficacy RCTs challenging and/or impractical, how comparative effectiveness research can be used to address these issues, and identify several key questions which would benefit from ongoing comparative effectiveness research.
authors: Department of Surgery, University of Wisconsin Hospital and Clinics, Madison, WI, USA, LFrasier@uwhealth.org.
authors: Lane L
authors: LL
authors: Frasier
authors: Caprice C
authors: CC
authors: Greenberg
authors: Heather B
authors: HB
authors: Neuman
mesh_terms: D001943:Breast Neoplasms / Q000401:mortality / Q000628:therapy; D057186:Comparative Effectiveness Research / Q000379:methods*; D005260:Female; D006801:Humans; D057240:Patient Preference; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome