title: Genetic studies of body mass index yield new insights for obesity biology.
abstract: Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals. This analysis identifies 97 BMI-associated loci (P < 5 × 10(-8)), 56 of which are novel. Five loci demonstrate clear evidence of several independent association signals, and many loci have significant effects on other metabolic phenotypes. The 97 loci account for ∼2.7% of BMI variation, and genome-wide estimates suggest that common variation accounts for >20% of BMI variation. Pathway analyses provide strong support for a role of the central nervous system in obesity susceptibility and implicate new genes and pathways, including those related to synaptic function, glutamate signalling, insulin secretion/action, energy metabolism, lipid biology and adipogenesis.
authors: Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Adam E
authors: AE
authors: Locke
authors: Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Bratati
authors: B
authors: Kahali
authors: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors: Sonja I
authors: SI
authors: Berndt
authors: Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
authors: Anne E
authors: AE
authors: Justice
authors: Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.|Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.|Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.|Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby 2800, Denmark.
authors: Tune H
authors: TH
authors: Pers
authors: MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
authors: Felix R
authors: FR
authors: Day
authors: Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Corey
authors: C
authors: Powell
authors: Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.|Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.
authors: Sailaja
authors: S
authors: Vedantam
authors: Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.
authors: Martin L
authors: ML
authors: Buchkovich
authors: Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.|The University of Queensland Diamantina Institute, The Translation Research Institute, Brisbane 4012, Australia.
authors: Jian
authors: J
authors: Yang
authors: Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.|Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
authors: Damien C
authors: DC
authors: Croteau-Chonka
authors: Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.|Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.|Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.|Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
authors: Tonu
authors: T
authors: Esko
authors: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.|Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.|Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.
authors: Tove
authors: T
authors: Fall
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
authors: Teresa
authors: T
authors: Ferreira
authors: Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.|Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.
authors: Stefan
authors: S
authors: Gustafsson
authors: Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne 1010, Switzerland.|Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.|Department of Medical Genetics, University of Lausanne, Lausanne 1005, Switzerland.
authors: Zoltán
authors: Z
authors: Kutalik
authors: MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
authors: Jian'an
authors: J
authors: Luan
authors: Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.|Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
authors: Reedik
authors: R
authors: Mägi
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.
authors: Joshua C
authors: JC
authors: Randall
authors: Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.
authors: Thomas W
authors: TW
authors: Winkler
authors: Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
authors: Andrew R
authors: AR
authors: Wood
authors: Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
authors: Tsegaselassie
authors: T
authors: Workalemahu
authors: Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan 48104, USA.
authors: Jessica D
authors: JD
authors: Faul
authors: Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Jennifer A
authors: JA
authors: Smith
authors: MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
authors: Jing Hua
authors: JH
authors: Zhao
authors: Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Wei
authors: W
authors: Zhao
authors: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Jin
authors: J
authors: Chen
authors: Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Rudolf
authors: R
authors: Fehrmann
authors: Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.|Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.|Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
authors: Åsa K
authors: ÅK
authors: Hedman
authors: Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Juha
authors: J
authors: Karjalainen
authors: Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Ellen M
authors: EM
authors: Schmidt
authors: HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA.
authors: Devin
authors: D
authors: Absher
authors: Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.
authors: Najaf
authors: N
authors: Amin
authors: Telethon Institute for Child Health Research, Centre for Child Health Research, The University of Western Australia, Perth, Western Australia 6008, Australia.
authors: Denise
authors: D
authors: Anderson
authors: Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.|Department of Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
authors: Marian
authors: M
authors: Beekman
authors: Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.
authors: Jennifer L
authors: JL
authors: Bolton
authors: Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.|Kidney Epidemiology and Cost Center, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Jennifer L
authors: JL
authors: Bragg-Gresham
authors: Department of Statistics & Biostatistics, Rutgers University, Piscataway, New Jersey 08854, USA.|Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA.
authors: Steven
authors: S
authors: Buyske
authors: Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.|Department of Human Genetics, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
authors: Ayse
authors: A
authors: Demirkan
authors: Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.|Department of Gastroenterology and Hepatology, Imperial College London, London W2 1PG, UK.|Institute of infectious Diseases, Southwest Hospital, Third Military Medical University, Chongqing, China.
authors: Guohong
authors: G
authors: Deng
authors: Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.|Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva 1211, Switzerland.
authors: Georg B
authors: GB
authors: Ehret
authors: Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.
authors: Bjarke
authors: B
authors: Feenstra
authors: Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: Mary F
authors: MF
authors: Feitosa
authors: Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
authors: Krista
authors: K
authors: Fischer
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
authors: Anuj
authors: A
authors: Goel
authors: Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
authors: Jian
authors: J
authors: Gong
authors: Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Anne U
authors: AU
authors: Jackson
authors: William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
authors: Stavroula
authors: S
authors: Kanoni
authors: Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.|Department of Internal Medicine II, Ulm University Medical Centre, D-89081 Ulm, Germany.
authors: Marcus E
authors: ME
authors: Kleber
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
authors: Kati
authors: K
authors: Kristiansson
authors: Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.
authors: Unhee
authors: U
authors: Lim
authors: The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
authors: Vaneet
authors: V
authors: Lotay
authors: Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.
authors: Massimo
authors: M
authors: Mangino
authors: Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.
authors: Irene Mateo
authors: IM
authors: Leach
authors: Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.|Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.|Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.
authors: Carolina
authors: C
authors: Medina-Gomez
authors: QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.
authors: Sarah E
authors: SE
authors: Medland
authors: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors: Michael A
authors: MA
authors: Nalls
authors: Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.|Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.
authors: Cameron D
authors: CD
authors: Palmer
authors: Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
authors: Dorota
authors: D
authors: Pasko
authors: Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.
authors: Sonali
authors: S
authors: Pechlivanis
authors: Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.|Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.
authors: Marjolein J
authors: MJ
authors: Peters
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.|Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.
authors: Inga
authors: I
authors: Prokopenko
authors: Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.|Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.|Department of Odontology, Umeå University, Umeå 901 85, Sweden.
authors: Dmitry
authors: D
authors: Shungin
authors: University of Eastern Finland, FI-70210 Kuopio, Finland.
authors: Alena
authors: A
authors: Stančáková
authors: Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
authors: Rona J
authors: RJ
authors: Strawbridge
authors: Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: Yun Ju
authors: YJ
authors: Sung
authors: Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.
authors: Toshiko
authors: T
authors: Tanaka
authors: Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.
authors: Alexander
authors: A
authors: Teumer
authors: Department of Cardiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.|Department of Gerontology and Geriatrics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
authors: Stella
authors: S
authors: Trompet
authors: Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
authors: Sander W
authors: SW
authors: van der Laan
authors: Department of Medical Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
authors: Jessica
authors: J
authors: van Setten
authors: Department of Endocrinology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands.
authors: Jana V
authors: JV
authors: Van Vliet-Ostaptchouk
authors: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.|Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland 21702, USA.
authors: Zhaoming
authors: Z
authors: Wang
authors: CNRS UMR 8199, F-59019 Lille, France.|European Genomic Institute for Diabetes, F-59000 Lille, France.|Université de Lille 2, F-59000 Lille, France.
authors: Loïc
authors: L
authors: Yengo
authors: Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.|Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.
authors: Weihua
authors: W
authors: Zhang
authors: Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.|Center for Medical Sytems Biology, 2300 RC Leiden, The Netherlands.
authors: Aaron
authors: A
authors: Isaacs
authors: Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
authors: Eva
authors: E
authors: Albrecht
authors: Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.|Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.|School of Health and Social Studies, Dalarna University, SE-791 88 Falun, Sweden.
authors: Johan
authors: J
authors: Ärnlöv
authors: PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.
authors: Gillian M
authors: GM
authors: Arscott
authors: Department of Haematology, University of Cambridge, Cambridge CB2 0PT, UK.|NHS Blood and Transplant, Cambridge CB2 0PT, UK.
authors: Antony P
authors: AP
authors: Attwood
authors: Geriatric Unit, Azienda Sanitaria Firenze (ASF), 50125 Florence, Italy.
authors: Stefania
authors: S
authors: Bandinelli
authors: Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
authors: Amy
authors: A
authors: Barrett
authors: USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.
authors: Isabelita N
authors: IN
authors: Bas
authors: Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78227, USA.|Genomics Research Centre, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4001, Australia.
authors: Claire
authors: C
authors: Bellis
authors: Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
authors: Amanda J
authors: AJ
authors: Bennett
authors: Department of Medical Sciences, Endocrinology, Diabetes and Metabolism, Uppsala University, Uppsala 75185, Sweden.
authors: Christian
authors: C
authors: Berne
authors: Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, D-89081 Ulm, Germany.
authors: Roza
authors: R
authors: Blagieva
authors: Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.|Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.
authors: Matthias
authors: M
authors: Blüher
authors: Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.|Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
authors: Stefan
authors: S
authors: Böhringer
authors: Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.
authors: Lori L
authors: LL
authors: Bonnycastle
authors: Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.
authors: Yvonne
authors: Y
authors: Böttcher
authors: Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.
authors: Heather A
authors: HA
authors: Boyd
authors: LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Marcel
authors: M
authors: Bruinenberg
authors: Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
authors: Ida H
authors: IH
authors: Caspersen
authors: Department of Pediatrics, University of California Los Angeles, Torrance, California 90502, USA.|Transgenomics Institute, Los Angeles Biomedical Research Institute, Torrance, California 90502, USA.
authors: Yii-Der Ida
authors: YI
authors: Chen
authors: Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.
authors: Robert
authors: R
authors: Clarke
authors: Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: E Warwick
authors: EW
authors: Daw
authors: Department of Gerontology and Geriatrics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
authors: Anton J M
authors: AJM
authors: de Craen
authors: Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.
authors: Graciela
authors: G
authors: Delgado
authors: Department of Dietetics-Nutrition, Harokopio University, 17671 Athens, Greece.
authors: Maria
authors: M
authors: Dimitriou
authors: Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
authors: Alex S F
authors: ASF
authors: Doney
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.|Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.
authors: Niina
authors: N
authors: Eklund
authors: Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.|Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.|Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.
authors: Karol
authors: K
authors: Estrada
authors: CNRS UMR 8199, F-59019 Lille, France.|European Genomic Institute for Diabetes, F-59000 Lille, France.|Université de Lille 2, F-59000 Lille, France.
authors: Elodie
authors: E
authors: Eury
authors: Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
authors: Lasse
authors: L
authors: Folkersen
authors: Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.
authors: Ross M
authors: RM
authors: Fraser
authors: Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, Maryland 20892, USA.
authors: Melissa E
authors: ME
authors: Garcia
authors: Department of Epidemiology Research, Statens Serum Institut, Copenhagen DK-2300, Denmark.
authors: Frank
authors: F
authors: Geller
authors: Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala 75185, Sweden.
authors: Vilmantas
authors: V
authors: Giedraitis
authors: Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.
authors: Bruna
authors: B
authors: Gigante
authors: Kaiser Permanente, Division of Research, Oakland, California 94612, USA.
authors: Alan S
authors: AS
authors: Go
authors: Service of Therapeutic Education for Diabetes, Obesity and Chronic Diseases, Geneva University Hospital, Geneva CH-1211, Switzerland.
authors: Alain
authors: A
authors: Golay
authors: Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.|National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK.
authors: Alison H
authors: AH
authors: Goodall
authors: QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.
authors: Scott D
authors: SD
authors: Gordon
authors: Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.|Department of Nephrology, University Hospital Regensburg, D-93053 Regensburg, Germany.
authors: Mathias
authors: M
authors: Gorski
authors: Department of Psychiatry and Psychotherapy, University Medicine Greifswald, HELIOS-Hospital Stralsund, D-17475 Greifswald, Germany.|German Center for Neurodegenerative Diseases (DZNE), Rostock, Greifswald, D-17475 Greifswald, Germany.
authors: Hans-Jörgen
authors: HJ
authors: Grabe
authors: Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.|Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.|German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.
authors: Harald
authors: H
authors: Grallert
authors: Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.
authors: Tanja B
authors: TB
authors: Grammer
authors: Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.
authors: Jürgen
authors: J
authors: Gräßler
authors: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.
authors: Henrik
authors: H
authors: Grönberg
authors: Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
authors: Christopher J
authors: CJ
authors: Groves
authors: Institut inter Régional pour la Santé, Synergies, F-37520 La Riche, France.
authors: Gaëlle
authors: G
authors: Gusto
authors: Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
authors: Jeffrey
authors: J
authors: Haessler
authors: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.
authors: Per
authors: P
authors: Hall
authors: Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
authors: Toomas
authors: T
authors: Haller
authors: Department of Public Health and Clinical Medicine, Unit of Nutritional Research, Umeå University, Umeå 90187, Sweden.
authors: Goran
authors: G
authors: Hallmans
authors: Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.
authors: Catharina A
authors: CA
authors: Hartman
authors: Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.
authors: Maija
authors: M
authors: Hassinen
authors: MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.
authors: Caroline
authors: C
authors: Hayward
authors: National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.|Department of Neurology, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
authors: Nancy L
authors: NL
authors: Heard-Costa
authors: Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.|Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.|Faculty of Psychology and Education, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.
authors: Quinta
authors: Q
authors: Helmer
authors: Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.|Deutsches Herzzentrum München, Technische Universität München, D-80636 Munich, Germany.
authors: Christian
authors: C
authors: Hengstenberg
authors: Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway.
authors: Oddgeir
authors: O
authors: Holmen
authors: Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.
authors: Jouke-Jan
authors: JJ
authors: Hottenga
authors: Department of Pulmonary Physiology and Sleep Medicine, Nedlands, Western Australia 6009, Australia.|School of Medicine and Pharmacology, University of Western Australia, Crawley 6009, Australia.
authors: Alan L
authors: AL
authors: James
authors: The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
authors: Janina M
authors: JM
authors: Jeff
authors: Uppsala University, Department of Immunology, Genetics, Pathology, SciLifeLab, Rudbeck Laboratory, SE-751 85 Uppsala, Sweden.
authors: Åsa
authors: Å
authors: Johansson
authors: Department of Haematology, University of Cambridge, Cambridge CB2 0PT, UK.|NHS Blood and Transplant, Cambridge CB2 0PT, UK.
authors: Jennifer
authors: J
authors: Jolley
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
authors: Thorhildur
authors: T
authors: Juliusdottir
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
authors: Leena
authors: L
authors: Kinnunen
authors: Department of Internal Medicine II, Ulm University Medical Centre, D-89081 Ulm, Germany.
authors: Wolfgang
authors: W
authors: Koenig
authors: Hjelt Institute Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland.
authors: Markku
authors: M
authors: Koskenvuo
authors: Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.
authors: Wolfgang
authors: W
authors: Kratzer
authors: Finnish Institute of Occupational Health, FI-90100 Oulu, Finland.
authors: Jaana
authors: J
authors: Laitinen
authors: Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, 6020 Innsbruck, Austria.
authors: Claudia
authors: C
authors: Lamina
authors: Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.
authors: Karin
authors: K
authors: Leander
authors: USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City 6000, Philippines.
authors: Nanette R
authors: NR
authors: Lee
authors: Institute of Human Genetics, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
authors: Peter
authors: P
authors: Lichtner
authors: Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden.
authors: Lars
authors: L
authors: Lind
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
authors: Jaana
authors: J
authors: Lindström
authors: Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.
authors: Ken Sin
authors: KS
authors: Lo
authors: CNRS UMR 8199, F-59019 Lille, France.|European Genomic Institute for Diabetes, F-59000 Lille, France.|Université de Lille 2, F-59000 Lille, France.
authors: Stéphane
authors: S
authors: Lobbens
authors: Institute for Community Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.
authors: Roberto
authors: R
authors: Lorbeer
authors: The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.|The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
authors: Yingchang
authors: Y
authors: Lu
authors: Cardiology, Department of Specialties of Internal Medicine, Geneva University Hospital, Geneva 1211, Switzerland.
authors: François
authors: F
authors: Mach
authors: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.
authors: Patrik K E
authors: PKE
authors: Magnusson
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
authors: Anubha
authors: A
authors: Mahajan
authors: School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.
authors: Wendy L
authors: WL
authors: McArdle
authors: Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.
authors: Stela
authors: S
authors: McLachlan
authors: Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.
authors: Cristina
authors: C
authors: Menni
authors: Division of Endocrinology, Diabetes and Metabolism, Ulm University Medical Centre, D-89081 Ulm, Germany.
authors: Sigrun
authors: S
authors: Merger
authors: Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.|Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia.
authors: Evelin
authors: E
authors: Mihailov
authors: Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
authors: Lili
authors: L
authors: Milani
authors: Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.|Farr Institute of Health Informatics Research, University College London, London NW1 2DA, UK.
authors: Alireza
authors: A
authors: Moayyeri
authors: Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.|The Center for Observational Research, Amgen, Inc., Thousand Oaks, California 91320, USA.
authors: Keri L
authors: KL
authors: Monda
authors: Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.
authors: Mario A
authors: MA
authors: Morken
authors: Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy.
authors: Antonella
authors: A
authors: Mulas
authors: Center for Evidence-based Healthcare, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.
authors: Gabriele
authors: G
authors: Müller
authors: Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.|Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.|Department of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.|Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.
authors: Martina
authors: M
authors: Müller-Nurasyid
authors: Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia.
authors: Arthur W
authors: AW
authors: Musk
authors: Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland 21224, USA.
authors: Ramaiah
authors: R
authors: Nagaraja
authors: Department of Genomics, Life & Brain Center, University of Bonn, 53127 Bonn, Germany.|Institute of Human Genetics, University of Bonn, 53127 Bonn, Germany.
authors: Markus M
authors: MM
authors: Nöthen
authors: Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Ilja M
authors: IM
authors: Nolte
authors: Department of Epidemiology and Biostatistics, Institute for Research in Extramural Medicine, Institute for Health and Care Research, VU University Medical Center, 1081BT Amsterdam, The Netherlands.|Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, 8036 Graz, Austria.
authors: Stefan
authors: S
authors: Pilz
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.|Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
authors: Nigel W
authors: NW
authors: Rayner
authors: Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.
authors: Frida
authors: F
authors: Renstrom
authors: Institute of Physiology, University Medicine Greifswald, D-17495 Karlsburg, Germany.
authors: Rainer
authors: R
authors: Rettig
authors: Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
authors: Janina S
authors: JS
authors: Ried
authors: Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.|Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
authors: Stephan
authors: S
authors: Ripke
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.
authors: Neil R
authors: NR
authors: Robertson
authors: Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.
authors: Lynda M
authors: LM
authors: Rose
authors: Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, Cagliari, Sardinia 09042, Italy.
authors: Serena
authors: S
authors: Sanna
authors: Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria.
authors: Hubert
authors: H
authors: Scharnagl
authors: LifeLines Cohort Study, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Salome
authors: S
authors: Scholtens
authors: Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.
authors: Fredrick R
authors: FR
authors: Schumacher
authors: Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.|Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.
authors: William R
authors: WR
authors: Scott
authors: Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.
authors: Thomas
authors: T
authors: Seufferlein
authors: National Cancer Institute, Bethesda, Maryland 20892, USA.
authors: Jianxin
authors: J
authors: Shi
authors: Icelandic Heart Association, Kopavogur 201, Iceland.|University of Iceland, Reykjavik 101, Iceland.
authors: Albert Vernon
authors: AV
authors: Smith
authors: Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.|Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Joanna
authors: J
authors: Smolonska
authors: Molecular & Cellular Therapeutics, Royal College of Surgeons in Ireland, 123 St Stephen's Green, Dublin 2, Ireland.
authors: Alice V
authors: AV
authors: Stanton
authors: deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.
authors: Valgerdur
authors: V
authors: Steinthorsdottir
authors: Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.|William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
authors: Kathleen
authors: K
authors: Stirrups
authors: Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Heather M
authors: HM
authors: Stringham
authors: Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala 75185, Sweden.
authors: Johan
authors: J
authors: Sundström
authors: Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Morris A
authors: MA
authors: Swertz
authors: Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.
authors: Amy J
authors: AJ
authors: Swift
authors: Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.|Department of Medical Sciences, Molecular Medicine, Uppsala University, Uppsala 75144, Sweden.
authors: Ann-Christine
authors: AC
authors: Syvänen
authors: Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.|National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.
authors: Sian-Tsung
authors: ST
authors: Tan
authors: Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA.
authors: Bamidele O
authors: BO
authors: Tayo
authors: German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.|Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.
authors: Barbara
authors: B
authors: Thorand
authors: deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.
authors: Gudmar
authors: G
authors: Thorleifsson
authors: Department of Oncology, University of Cambridge, Cambridge CB2 0QQ, UK.
authors: Jonathan P
authors: JP
authors: Tyrer
authors: Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.|Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
authors: Hae-Won
authors: HW
authors: Uh
authors: Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.
authors: Liesbeth
authors: L
authors: Vandenput
authors: Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC University Medical Centre, 3000 CB Rotterdam, The Netherlands.
authors: Frank C
authors: FC
authors: Verhulst
authors: Department for Health Evidence, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.|Department of Genetics, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.
authors: Sita H
authors: SH
authors: Vermeulen
authors: Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.
authors: Niek
authors: N
authors: Verweij
authors: Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Judith M
authors: JM
authors: Vonk
authors: HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA.
authors: Lindsay L
authors: LL
authors: Waite
authors: Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
authors: Helen R
authors: HR
authors: Warren
authors: Genetics, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA.
authors: Dawn
authors: D
authors: Waterworth
authors: Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
authors: Michael N
authors: MN
authors: Weedon
authors: Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.
authors: Lynne R
authors: LR
authors: Wilkens
authors: German Center for Cardiovascular Research, partner site Hamburg/Lubeck/Kiel, 23562 Lubeck, Germany.|Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, D-23562 Lübeck, Germany.
authors: Christina
authors: C
authors: Willenborg
authors: Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, 9037 Tromsø, Norway.
authors: Tom
authors: T
authors: Wilsgaard
authors: Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: Mary K
authors: MK
authors: Wojczynski
authors: MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.
authors: Andrew
authors: A
authors: Wong
authors: MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.
authors: Alan F
authors: AF
authors: Wright
authors: Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: Qunyuan
authors: Q
authors: Zhang
authors: Diabetes Complications Research Centre, Conway Institute, School of Medicine and Medical Sciences, University College Dublin, Dublin 4, Ireland.
authors: Eoin P
authors: EP
authors: Brennan
authors: Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
authors: Murim
authors: M
authors: Choi
authors: Lady Davis Institute, Departments of Human Genetics, Epidemiology and Biostatistics, McGill University, Montréal, Québec H3T1E2, Canada.
authors: Zari
authors: Z
authors: Dastani
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
authors: Alexander W
authors: AW
authors: Drong
authors: Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
authors: Per
authors: P
authors: Eriksson
authors: Cardiothoracic Surgery Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm 17176, Sweden.
authors: Anders
authors: A
authors: Franco-Cereceda
authors: Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
authors: Jesper R
authors: JR
authors: Gådin
authors: Department of Medicine, Columbia University College of Physicians and Surgeons, New York 10032, USA.
authors: Ali G
authors: AG
authors: Gharavi
authors: Biosciences Research Division, Department of Primary Industries, Victoria 3083, Australia.|Department of Food and Agricultural Systems, University of Melbourne, Victoria 3010, Australia.
authors: Michael E
authors: ME
authors: Goddard
authors: Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.|Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
authors: Robert E
authors: RE
authors: Handsaker
authors: Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.|State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China.
authors: Jinyan
authors: J
authors: Huang
authors: Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.|NIHR Oxford Biomedical Research Centre, OUH Trust, Oxford OX3 7LE, UK.
authors: Fredrik
authors: F
authors: Karpe
authors: Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.|Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors: Sekar
authors: S
authors: Kathiresan
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
authors: Sarah
authors: S
authors: Keildson
authors: Department of Medicine, Columbia University College of Physicians and Surgeons, New York 10032, USA.
authors: Krzysztof
authors: K
authors: Kiryluk
authors: Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.
authors: Michiaki
authors: M
authors: Kubo
authors: Center for Genome Science, National Institute of Health, Chungcheongbuk-do, Chungbuk 363-951, Republic of Korea.
authors: Jong-Young
authors: JY
authors: Lee
authors: Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.|Harvard School of Public Health, Department of Biostatistics, Harvard University, Boston, Massachusetts 2115, USA.
authors: Liming
authors: L
authors: Liang
authors: Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, New Haven, Connecticut 06520, USA.
authors: Richard P
authors: RP
authors: Lifton
authors: Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.|College of Information Science and Technology, Dalian Maritime University, Dalian, Liaoning 116026, China.
authors: Baoshan
authors: B
authors: Ma
authors: Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.|Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.|Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
authors: Steven A
authors: SA
authors: McCarroll
authors: Nephrology Research, Centre for Public Health, Queen's University of Belfast, Belfast, County Down BT9 7AB, UK.
authors: Amy J
authors: AJ
authors: McKnight
authors: School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, UK.
authors: Josine L
authors: JL
authors: Min
authors: National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.
authors: Miriam F
authors: MF
authors: Moffatt
authors: QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.
authors: Grant W
authors: GW
authors: Montgomery
authors: National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.|Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, USA.
authors: Joanne M
authors: JM
authors: Murabito
authors: Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK.|MRC Harwell, Harwell Science and Innovation Campus, Harwell OX11 0QG, UK.
authors: George
authors: G
authors: Nicholson
authors: QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.|Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4059, Australia.
authors: Dale R
authors: DR
authors: Nyholt
authors: Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.|Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.
authors: Yukinori
authors: Y
authors: Okada
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.|Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.
authors: John R B
authors: JRB
authors: Perry
authors: Genome Institute of Singapore, Agency for Science, Technology and Research, 138672 Singapore.
authors: Rajkumar
authors: R
authors: Dorajoo
authors: Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
authors: Eva
authors: E
authors: Reinmaa
authors: Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.|Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.|Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
authors: Rany M
authors: RM
authors: Salem
authors: Department of Biomedical Engineering and Computational Science, Aalto University School of Science, Helsinki FI-00076, Finland.|Department of Medicine, Division of Nephrology, Helsinki University Central Hospital, FI-00290 Helsinki, Finland.|Folkhälsan Institute of Genetics, Folkhälsan Research Center, FI-00290 Helsinki, Finland.
authors: Niina
authors: N
authors: Sandholm
authors: MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
authors: Robert A
authors: RA
authors: Scott
authors: Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.|Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.
authors: Lisette
authors: L
authors: Stolk
authors: Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.
authors: Atsushi
authors: A
authors: Takahashi
authors: Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.|Laboratory for Cardiovascular Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama 230-0045, Japan.|Division of Disease Diversity, Bioresource Research Center, Tokyo Medical and Dental University, 113-8510 Tokyo, Japan.
authors: Toshihiro
authors: T
authors: Tanaka
authors: Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
authors: Ferdinand M
authors: FM
authors: van 't Hooft
authors: Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.
authors: Anna A E
authors: AAE
authors: Vinkhuyzen
authors: Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Harm-Jan
authors: HJ
authors: Westra
authors: Division of Epidemiology, Department of Medicine; Vanderbilt Epidemiology Center; and Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37075, USA.
authors: Wei
authors: W
authors: Zheng
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Nuffield Department of Obstetrics & Gynaecology, University of Oxford, Oxford OX3 7BN, UK.
authors: Krina T
authors: KT
authors: Zondervan
authors: Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: Andrew C
authors: AC
authors: Heath
authors: Department of Epidemiology and Public Health, EA3430, University of Strasbourg, Faculty of Medicine, Strasbourg, France.
authors: Dominique
authors: D
authors: Arveiler
authors: Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.
authors: Stephan J L
authors: SJL
authors: Bakker
authors: PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.|Pathology and Laboratory Medicine, The University of Western Australia, Perth, Western Australia 6009, Australia.
authors: John
authors: J
authors: Beilby
authors: Cedars-Sinai Diabetes and Obesity Research Institute, Los Angeles, California 90048, USA.
authors: Richard N
authors: RN
authors: Bergman
authors: Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78227, USA.
authors: John
authors: J
authors: Blangero
authors: Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, 1010 Lausanne, Switzerland.|Ministry of Health, Victoria, Republic of Seychelles.
authors: Pascal
authors: P
authors: Bovet
authors: Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.
authors: Harry
authors: H
authors: Campbell
authors: Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
authors: Mark J
authors: MJ
authors: Caulfield
authors: University of Milano, Bicocca, 20126, Italy.
authors: Giancarlo
authors: G
authors: Cesana
authors: Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
authors: Aravinda
authors: A
authors: Chakravarti
authors: Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.|Harvard Medical School, Boston, Massachusetts 02115, USA.
authors: Daniel I
authors: DI
authors: Chasman
authors: Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.
authors: Peter S
authors: PS
authors: Chines
authors: Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892, USA.
authors: Francis S
authors: FS
authors: Collins
authors: Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, Tennessee 37203, USA.|Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37232, USA.
authors: Dana C
authors: DC
authors: Crawford
authors: National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.|Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.
authors: L Adrienne
authors: LA
authors: Cupples
authors: Department of Health Sciences, University of Milano, I 20142, Italy.|Fondazione Filarete, Milano I 20139, Italy.
authors: Daniele
authors: D
authors: Cusi
authors: Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.
authors: John
authors: J
authors: Danesh
authors: Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Stockholm 17177, Sweden.
authors: Ulf
authors: U
authors: de Faire
authors: Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.|Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
authors: Hester M
authors: HM
authors: den Ruijter
authors: Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK.
authors: Anna F
authors: AF
authors: Dominiczak
authors: Clinic of Cardiology, West-German Heart Centre, University Hospital Essen, 45147 Essen, Germany.
authors: Raimund
authors: R
authors: Erbel
authors: German Center for Cardiovascular Research, partner site Hamburg/Lubeck/Kiel, 23562 Lubeck, Germany.|Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, D-23562 Lübeck, Germany.
authors: Jeanette
authors: J
authors: Erdmann
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.|Department of General Practice and Primary Health Care, University of Helsinki, FI-00290 Helsinki, Finland.|Unit of General Practice, Helsinki University Central Hospital, Helsinki 00290, Finland.
authors: Johan G
authors: JG
authors: Eriksson
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
authors: Martin
authors: M
authors: Farrall
authors: Department of Internal Medicine B, University Medicine Greifswald, D-17475 Greifswald, Germany.|DZHK (Deutsches Zentrum für Herz-Kreislaufforschung - German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany.
authors: Stephan B
authors: SB
authors: Felix
authors: Department of Internal Medicine, University of Pisa, 56100 Pisa, Italy.|National Research Council Institute of Clinical Physiology, University of Pisa, 56124 Pisa, Italy.
authors: Ele
authors: E
authors: Ferrannini
authors: Department of Cardiology, Toulouse University School of Medicine, Rangueil Hospital, 31400 Toulouse, France.
authors: Jean
authors: J
authors: Ferrières
authors: Robertson Center for Biostatistics, University of Glasgow, Glasgow G12 8QQ, UK.
authors: Ian
authors: I
authors: Ford
authors: MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
authors: Nita G
authors: NG
authors: Forouhi
authors: UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica.
authors: Terrence
authors: T
authors: Forrester
authors: Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.|Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.
authors: Oscar H
authors: OH
authors: Franco
authors: Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.
authors: Ron T
authors: RT
authors: Gansevoort
authors: NorthShore University HealthSystem, Evanston, IL 60201, University of Chicago, Chicago, Illinois, USA.
authors: Pablo V
authors: PV
authors: Gejman
authors: Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
authors: Christian
authors: C
authors: Gieger
authors: The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
authors: Omri
authors: O
authors: Gottesman
authors: Icelandic Heart Association, Kopavogur 201, Iceland.|University of Iceland, Reykjavik 101, Iceland.
authors: Vilmundur
authors: V
authors: Gudnason
authors: Uppsala University, Department of Immunology, Genetics, Pathology, SciLifeLab, Rudbeck Laboratory, SE-751 85 Uppsala, Sweden.
authors: Ulf
authors: U
authors: Gyllensten
authors: Leeds MRC Medical Bioinformatics Centre, University of Leeds, Leeds LS2 9LU, UK.
authors: Alistair S
authors: AS
authors: Hall
authors: Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, Maryland 20892, USA.
authors: Tamara B
authors: TB
authors: Harris
authors: Institute of Biomedical & Clinical Science, University of Exeter, Barrack Road, Exeter EX2 5DW, UK.
authors: Andrew T
authors: AT
authors: Hattersley
authors: Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy (affiliated institute of the University of Lübeck, D-23562 Lübeck, Germany).
authors: Andrew A
authors: AA
authors: Hicks
authors: Division of Genomic Medicine, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors: Lucia A
authors: LA
authors: Hindorff
authors: Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.
authors: Aroon D
authors: AD
authors: Hingorani
authors: Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.|Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.
authors: Albert
authors: A
authors: Hofman
authors: Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.
authors: Georg
authors: G
authors: Homuth
authors: Department of Vascular Medicine, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.
authors: G Kees
authors: GK
authors: Hovingh
authors: Centre for Cardiovascular Genetics, Institute Cardiovascular Sciences, University College London, London WC1E 6JJ, UK.
authors: Steve E
authors: SE
authors: Humphries
authors: Cardiovascular Genetics Division, Department of Internal Medicine, University of Utah, Salt Lake City, Utah 84108, USA.
authors: Steven C
authors: SC
authors: Hunt
authors: Sansom Institute for Health Research, University of South Australia, Adelaide 5000, South Australia, Australia.|School of Population Health, University of South Australia, Adelaide 5000, South Australia, Australia.|South Australian Health and Medical Research Institute, Adelaide, South Australia 5000, Australia.|Population, Policy, and Practice, University College London Institute of Child Health, London WC1N 1EH, UK.
authors: Elina
authors: E
authors: Hyppönen
authors: Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.|Hannover Unified Biobank, Hannover Medical School, Hannover, D-30625 Hannover, Germany.
authors: Thomas
authors: T
authors: Illig
authors: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.|Core Genotyping Facility, SAIC-Frederick, Inc., NCI-Frederick, Frederick, Maryland 21702, USA.
authors: Kevin B
authors: KB
authors: Jacobs
authors: Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.|National Institute for Health and Welfare, FI-90101 Oulu, Finland.|MRC Health Protection Agency (HPA) Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.|Unit of Primary Care, Oulu University Hospital, FI-90220 Oulu, Finland.|Institute of Health Sciences, University of Oulu, FI-90014 Oulu, Finland.|Institute of Health Sciences, University of Oulu, FI-90014 Oulu, Finland.
authors: Marjo-Riitta
authors: MR
authors: Jarvelin
authors: Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.
authors: Karl-Heinz
authors: KH
authors: Jöckel
authors: Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
authors: Berit
authors: B
authors: Johansen
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
authors: Pekka
authors: P
authors: Jousilahti
authors: Department of Cardiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.|Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.|Interuniversity Cardiology Institute of the Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.
authors: J Wouter
authors: JW
authors: Jukema
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
authors: Antti M
authors: AM
authors: Jula
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.|Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.|Hjelt Institute Department of Public Health, University of Helsinki, FI-00014 Helsinki, Finland.
authors: Jaakko
authors: J
authors: Kaprio
authors: Department of Vascular Medicine, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.
authors: John J P
authors: JJP
authors: Kastelein
authors: Institute of Health Sciences, University of Oulu, FI-90014 Oulu, Finland.|Unit of Primary Health Care/General Practice, Oulu University Hospital, FI-90220 Oulu, Finland.
authors: Sirkka M
authors: SM
authors: Keinanen-Kiukaanniemi
authors: Department for Health Evidence, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.|Department of Urology, Radboud University Medical Centre, 6500 HB Nijmegen, The Netherlands.
authors: Lambertus A
authors: LA
authors: Kiemeney
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
authors: Paul
authors: P
authors: Knekt
authors: Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.|National Heart and Lung Institute, Imperial College London, London SW3 6LY, UK.|Imperial College Healthcare NHS Trust, London W12 0HS, UK.
authors: Jaspal S
authors: JS
authors: Kooner
authors: Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
authors: Charles
authors: C
authors: Kooperberg
authors: Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.|Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.
authors: Peter
authors: P
authors: Kovacs
authors: Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: Aldi T
authors: AT
authors: Kraja
authors: Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.|Department of Biological and Social Epidemiology, University of Essex, Wivenhoe Park, Colchester, Essex CO4 3SQ, UK.
authors: Meena
authors: M
authors: Kumari
authors: Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.
authors: Johanna
authors: J
authors: Kuusisto
authors: Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.|Department of Physiology, Institute of Biomedicine, University of Eastern Finland, Kuopio Campus, FI-70211 Kuopio, Finland.|Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.
authors: Timo A
authors: TA
authors: Lakka
authors: MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.|Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.
authors: Claudia
authors: C
authors: Langenberg
authors: Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA.
authors: Loic Le
authors: LL
authors: Marchand
authors: Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine University of Tampere, FI-33520 Tampere, Finland.
authors: Terho
authors: T
authors: Lehtimäki
authors: Steno Diabetes Center A/S, Gentofte DK-2820, Denmark.|Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö 221 00, Sweden.
authors: Valeriya
authors: V
authors: Lyssenko
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
authors: Satu
authors: S
authors: Männistö
authors: Institut Universitaire de Cardiologie et de Pneumologie de Québec, Faculty of Medicine, Laval University, Quebec, QC G1V 0A6, Canada.|Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.
authors: André
authors: A
authors: Marette
authors: Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA.
authors: Tara C
authors: TC
authors: Matise
authors: UWI Solutions for Developing Countries, The University of the West Indies, Mona, Kingston 7, Jamaica.
authors: Colin A
authors: CA
authors: McKenzie
authors: Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA.
authors: Barbara
authors: B
authors: McKnight
authors: Department of Surgery, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
authors: Frans L
authors: FL
authors: Moll
authors: Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
authors: Andrew D
authors: AD
authors: Morris
authors: Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.|Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Department of Biostatistics, University of Liverpool, Liverpool L69 3GA, UK.
authors: Andrew P
authors: AP
authors: Morris
authors: Department of Pediatrics, University of Iowa, Iowa City, Iowa 52242, USA.
authors: Jeffrey C
authors: JC
authors: Murray
authors: Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
authors: Mari
authors: M
authors: Nelis
authors: Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 45, Sweden.
authors: Claes
authors: C
authors: Ohlsson
authors: Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9700RB Groningen, The Netherlands.
authors: Albertine J
authors: AJ
authors: Oldehinkel
authors: MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.|MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.
authors: Ken K
authors: KK
authors: Ong
authors: Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: Pamela A F
authors: PAF
authors: Madden
authors: Experimental Cardiology Laboratory, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
authors: Gerard
authors: G
authors: Pasterkamp
authors: Illumina, Inc, Little Chesterford, Cambridge CB10 1XL, UK.
authors: John F
authors: JF
authors: Peden
authors: Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.|Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.|Institute of Epidemiology II, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.
authors: Annette
authors: A
authors: Peters
authors: University of Groningen, University Medical Center Groningen, Department of Pulmonary Medicine and Tuberculosis, Groningen, The Netherlands.
authors: Dirkje S
authors: DS
authors: Postma
authors: Center for Biomedicine, European Academy Bozen, Bolzano (EURAC), Bolzano 39100, Italy (affiliated institute of the University of Lübeck, D-23562 Lübeck, Germany).|Department of Neurology, General Central Hospital, Bolzano 39100, Italy.
authors: Peter P
authors: PP
authors: Pramstaller
authors: Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.
authors: Jackie F
authors: JF
authors: Price
authors: Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.|Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
authors: Lu
authors: L
authors: Qi
authors: Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.|Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FI-20521 Turku, Finland.
authors: Olli T
authors: OT
authors: Raitakari
authors: Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.
authors: Tuomo
authors: T
authors: Rankinen
authors: Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.|Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.|Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: D C
authors: DC
authors: Rao
authors: Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.|Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: Treva K
authors: TK
authors: Rice
authors: Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.|Harvard Medical School, Boston, Massachusetts 02115, USA.
authors: Paul M
authors: PM
authors: Ridker
authors: Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada.|Université de Montréal, Montreal, Quebec H1T 1C8, Canada.
authors: John D
authors: JD
authors: Rioux
authors: Center for Systems Genomics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
authors: Marylyn D
authors: MD
authors: Ritchie
authors: Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.|Croatian Centre for Global Health, Faculty of Medicine, University of Split, 21000 Split, Croatia.
authors: Igor
authors: I
authors: Rudan
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
authors: Veikko
authors: V
authors: Salomaa
authors: Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester LE3 9QP, UK.|National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK.
authors: Nilesh J
authors: NJ
authors: Samani
authors: South Carelia Central Hospital, 53130 Lappeenranta, Finland.
authors: Jouko
authors: J
authors: Saramies
authors: Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.
authors: Mark A
authors: MA
authors: Sarzynski
authors: Deutsches Forschungszentrum für Herz-Kreislauferkrankungen (DZHK) (German Research Centre for Cardiovascular Research), Munich Heart Alliance, D-80636 Munich, Germany.|Deutsches Herzzentrum München, Technische Universität München, D-80636 Munich, Germany.
authors: Heribert
authors: H
authors: Schunkert
authors: Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.|Paul Langerhans Institute Dresden, German Center for Diabetes Research (DZD), 01307 Dresden, Germany.
authors: Peter E H
authors: PEH
authors: Schwarz
authors: International Centre for Circulatory Health, Imperial College London, London W2 1PG, UK.
authors: Peter
authors: P
authors: Sever
authors: Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.|Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.|Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland 21201, USA.
authors: Alan R
authors: AR
authors: Shuldiner
authors: Helsinki University Central Hospital Heart and Lung Center, Department of Medicine, Helsinki University Central Hospital, FI-00290 Helsinki, Finland.
authors: Juha
authors: J
authors: Sinisalo
authors: Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Ronald P
authors: RP
authors: Stolk
authors: Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.|Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, D-81377 Munich, Germany.
authors: Konstantin
authors: K
authors: Strauch
authors: Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.|Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.
authors: Anke
authors: A
authors: Tönjes
authors: Sorbonne Universités, UPMC Univ Paris 06, UMR S 1166, F-75013 Paris, France.|INSERM, UMR S 1166, Team Genomics and Physiopathology of Cardiovascular Diseases, F-75013 Paris, France.|Institute for Cardiometabolism And Nutrition (ICAN), F-75013 Paris, France.
authors: David-Alexandre
authors: DA
authors: Trégouët
authors: Department of Kinesiology, Laval University, Quebec QC G1V 0A6, Canada.
authors: Angelo
authors: A
authors: Tremblay
authors: Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano & Centro Cardiologico Monzino, Instituto di Ricovero e Cura a Carattere Scientifico, Milan 20133, Italy.
authors: Elena
authors: E
authors: Tremoli
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.
authors: Jarmo
authors: J
authors: Virtamo
authors: Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.|Department of Food Science and Nutrition, Laval University, Quebec QC G1V 0A6, Canada.
authors: Marie-Claude
authors: MC
authors: Vohl
authors: Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, D-17475 Greifswald, Germany.|DZHK (Deutsches Zentrum für Herz-Kreislaufforschung - German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany.
authors: Uwe
authors: U
authors: Völker
authors: Department of Internal Medicine, University Hospital (CHUV) and University of Lausanne, Lausanne 1011, Switzerland.
authors: Gérard
authors: G
authors: Waeber
authors: Biological Psychology, VU University Amsterdam, 1081BT Amsterdam, The Netherlands.
authors: Gonneke
authors: G
authors: Willemsen
authors: Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.
authors: Jacqueline C
authors: JC
authors: Witteman
authors: Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.|Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.
authors: M Carola
authors: MC
authors: Zillikens
authors: Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina 27599, USA.
authors: Linda S
authors: LS
authors: Adair
authors: Institut Pasteur de Lille; INSERM, U744; Université de Lille 2; F-59000 Lille, France.
authors: Philippe
authors: P
authors: Amouyel
authors: Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK.|Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.|Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
authors: Folkert W
authors: FW
authors: Asselbergs
authors: Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA.
authors: Themistocles L
authors: TL
authors: Assimes
authors: Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, 1010 Lausanne, Switzerland.|Ministry of Health, Victoria, Republic of Seychelles.
authors: Murielle
authors: M
authors: Bochud
authors: Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore, 637553 Singapore, Singapore.|Department of Internal Medicine I, Ulm University Medical Centre, D-89081 Ulm, Germany.
authors: Bernhard O
authors: BO
authors: Boehm
authors: Health Science Center at Houston, University of Texas, Houston, Texas 77030, USA.
authors: Eric
authors: E
authors: Boerwinkle
authors: Department of Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, D-01307 Dresden, Germany.
authors: Stefan R
authors: SR
authors: Bornstein
authors: The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
authors: Erwin P
authors: EP
authors: Bottinger
authors: Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA.
authors: Claude
authors: C
authors: Bouchard
authors: CNRS UMR 8199, F-59019 Lille, France.|European Genomic Institute for Diabetes, F-59000 Lille, France.|Université de Lille 2, F-59000 Lille, France.
authors: Stéphane
authors: S
authors: Cauchi
authors: Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.|Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.|Imperial College Healthcare NHS Trust, London W12 0HS, UK.
authors: John C
authors: JC
authors: Chambers
authors: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors: Stephen J
authors: SJ
authors: Chanock
authors: Department of Public Health Sciences, Stritch School of Medicine, Loyola University of Chicago, Maywood, Illinois 61053, USA.
authors: Richard S
authors: RS
authors: Cooper
authors: Department of Medical Genetics, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.|Department of Medicine, Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.|Department of Epidemiology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
authors: Paul I W
authors: PIW
authors: de Bakker
authors: Department of Dietetics-Nutrition, Harokopio University, 17671 Athens, Greece.
authors: George
authors: G
authors: Dedoussis
authors: Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA.
authors: Luigi
authors: L
authors: Ferrucci
authors: Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.|Department of Clinical Sciences, Genetic & Molecular Epidemiology Unit, Lund University Diabetes Center, Skåne University Hosptial, Malmö 205 02, Sweden.|Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå 901 87, Sweden.
authors: Paul W
authors: PW
authors: Franks
authors: Department of Genomics of Common Disease, School of Public Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.|CNRS UMR 8199, F-59019 Lille, France.|European Genomic Institute for Diabetes, F-59000 Lille, France.|Université de Lille 2, F-59000 Lille, France.
authors: Philippe
authors: P
authors: Froguel
authors: Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.|Lund University Diabetes Centre and Department of Clinical Science, Diabetes & Endocrinology Unit, Lund University, Malmö 221 00, Sweden.
authors: Leif C
authors: LC
authors: Groop
authors: Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.
authors: Christopher A
authors: CA
authors: Haiman
authors: Atherosclerosis Research Unit, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm 17176, Sweden.
authors: Anders
authors: A
authors: Hamsten
authors: PathWest Laboratory Medicine of Western Australia, Nedlands, Western Australia 6009, Australia.|Pathology and Laboratory Medicine, The University of Western Australia, Perth, Western Australia 6009, Australia.|School of Population Health, The University of Western Australia, Nedlands, Western Australia 6009, Australia.
authors: Jennie
authors: J
authors: Hui
authors: Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.|Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA.|Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
authors: David J
authors: DJ
authors: Hunter
authors: Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim 7489, Norway.
authors: Kristian
authors: K
authors: Hveem
authors: Albert Einstein College of Medicine, Department of Epidemiology and Population Health, Belfer 1306, New York 10461, USA.
authors: Robert C
authors: RC
authors: Kaplan
authors: Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK.
authors: Mika
authors: M
authors: Kivimaki
authors: MRC Unit for Lifelong Health and Ageing at University College London, London WC1B 5JU, UK.
authors: Diana
authors: D
authors: Kuh
authors: Department of Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.
authors: Markku
authors: M
authors: Laakso
authors: Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.
authors: Yongmei
authors: Y
authors: Liu
authors: QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4006, Australia.
authors: Nicholas G
authors: NG
authors: Martin
authors: Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, D-68187 Mannheim, Germany.|Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria.|Synlab Academy, Synlab Services GmbH, 68163 Mannheim, Germany.
authors: Winfried
authors: W
authors: März
authors: Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA.|Department of Clinical Medicine, Copenhagen University, 2200 Copenhagen, Denmark.
authors: Mads
authors: M
authors: Melbye
authors: Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.|Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia.
authors: Andres
authors: A
authors: Metspalu
authors: Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.
authors: Susanne
authors: S
authors: Moebus
authors: Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.
authors: Patricia B
authors: PB
authors: Munroe
authors: Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, 9037 Tromsø, Norway.
authors: Inger
authors: I
authors: Njølstad
authors: Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.|Center for Medical Sytems Biology, 2300 RC Leiden, The Netherlands.|Department of Clinical Genetics, Erasmus MC University Medical Center, 3000 CA Rotterdam, The Netherlands.
authors: Ben A
authors: BA
authors: Oostra
authors: Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
authors: Colin N A
authors: CNA
authors: Palmer
authors: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden.
authors: Nancy L
authors: NL
authors: Pedersen
authors: Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.|National Institute for Health and Welfare, FI-00271 Helsinki, Finland.|Institute for Molecular Medicine, University of Helsinki, FI-00014 Helsinki, Finland.
authors: Markus
authors: M
authors: Perola
authors: Institute of Nutrition and Functional Foods, Laval University, Quebec, QC G1V 0A6, Canada.|Department of Kinesiology, Laval University, Quebec QC G1V 0A6, Canada.
authors: Louis
authors: L
authors: Pérusse
authors: Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
authors: Ulrike
authors: U
authors: Peters
authors: Population, Policy, and Practice, University College London Institute of Child Health, London WC1N 1EH, UK.
authors: Chris
authors: C
authors: Power
authors: Department of Medicine, Stanford University School of Medicine, Palo Alto, California 94304, USA.
authors: Thomas
authors: T
authors: Quertermous
authors: Kuopio Research Institute of Exercise Medicine, 70100 Kuopio, Finland.|Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital and University of Eastern Finland, FI-70210 Kuopio, Finland.
authors: Rainer
authors: R
authors: Rauramaa
authors: Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.|Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.|Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.
authors: Fernando
authors: F
authors: Rivadeneira
authors: Finnish Diabetes Association, Kirjoniementie 15, FI-33680 Tampere, Finland.|Pirkanmaa Hospital District, FI-33521 Tampere, Finland.
authors: Timo E
authors: TE
authors: Saaristo
authors: Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK.|Center for Non-Communicable Diseases, Karatchi, Pakistan.|Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
authors: Danish
authors: D
authors: Saleheen
authors: BHF Glasgow Cardiovascular Research Centre, Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK.
authors: Naveed
authors: N
authors: Sattar
authors: Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10580, USA.
authors: Eric E
authors: EE
authors: Schadt
authors: Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland 21224, USA.
authors: David
authors: D
authors: Schlessinger
authors: Netherlands Consortium for Healthy Aging (NCHA), Leiden University Medical Center, Leiden 2300 RC, The Netherlands.|Department of Molecular Epidemiology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
authors: P Eline
authors: PE
authors: Slagboom
authors: Department of Epidemiology, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Harold
authors: H
authors: Snieder
authors: Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.
authors: Tim D
authors: TD
authors: Spector
authors: deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.|Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland.
authors: Unnur
authors: U
authors: Thorsteinsdottir
authors: Integrated Research and Treatment Center (IFB) Adiposity Diseases, University of Leipzig, D-04103 Leipzig, Germany.|Department of Medicine, University of Leipzig, D-04103 Leipzig, Germany.
authors: Michael
authors: M
authors: Stumvoll
authors: National Institute for Health and Welfare, FI-00271 Helsinki, Finland.|Institute for Health Research, University Hospital of La Paz (IdiPaz), 28046 Madrid, Spain.|Diabetes Research Group, King Abdulaziz University, 21589 Jeddah, Saudi Arabia.|Centre for Vascular Prevention, Danube-University Krems, 3500 Krems, Austria.
authors: Jaakko
authors: J
authors: Tuomilehto
authors: Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.|Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.|Department of Internal Medicine, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.
authors: André G
authors: AG
authors: Uitterlinden
authors: Department of Public Health and Clinical Nutrition, University of Eastern Finland, Finland.|Research Unit, Kuopio University Hospital, FI-70210 Kuopio, Finland.
authors: Matti
authors: M
authors: Uusitupa
authors: Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.|Department of Cardiology, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.|Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands (ICIN), 3501 DG Utrecht, The Netherlands.
authors: Pim
authors: P
authors: van der Harst
authors: Institute of Cellular Medicine, Newcastle University, Newcastle NE1 7RU, UK.
authors: Mark
authors: M
authors: Walker
authors: DZHK (Deutsches Zentrum für Herz-Kreislaufforschung - German Centre for Cardiovascular Research), partner site Greifswald, D-17475 Greifswald, Germany.|Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, D-17475 Greifswald, Germany.
authors: Henri
authors: H
authors: Wallaschofski
authors: MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.
authors: Nicholas J
authors: NJ
authors: Wareham
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Division of Cardiovacular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DU, UK.
authors: Hugh
authors: H
authors: Watkins
authors: Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, Michigan 48104, USA.
authors: David R
authors: DR
authors: Weir
authors: Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Ludwig-Maximilians-Universität, D-85764 Munich, Germany.|Klinikum Grosshadern, D-81377 Munich, Germany.|Institute of Epidemiology I, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, D-85764 Neuherberg, Germany.
authors: H-Erich
authors: HE
authors: Wichmann
authors: Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK.
authors: James F
authors: JF
authors: Wilson
authors: Department of Pulmonology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.
authors: Pieter
authors: P
authors: Zanen
authors: Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110, USA.
authors: Ingrid B
authors: IB
authors: Borecki
authors: Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.|William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.|Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, 21589 Jeddah, Saudi Arabia.
authors: Panos
authors: P
authors: Deloukas
authors: National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA.
authors: Caroline S
authors: CS
authors: Fox
authors: Department of Genetic Epidemiology, Institute of Epidemiology and Preventive Medicine, University of Regensburg, D-93053 Regensburg, Germany.|Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, D-85764 Neuherberg, Germany.
authors: Iris M
authors: IM
authors: Heid
authors: Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.|Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
authors: Jeffrey R
authors: JR
authors: O'Connell
authors: Division of Population Health Sciences & Education, St George's, University of London, London SW17 0RE, UK.
authors: David P
authors: DP
authors: Strachan
authors: deCODE Genetics, Amgen Inc., Reykjavik 101, Iceland.|Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland.
authors: Kari
authors: K
authors: Stefansson
authors: Genetic Epidemiology Unit, Department of Epidemiology, Erasmus MC University Medical Center, 3015 GE Rotterdam, The Netherlands.|Netherlands Consortium for Healthy Aging (NCHA), 3015GE Rotterdam, The Netherlands.|Department of Epidemiology, Erasmus MC University Medical Center, 3015GE Rotterdam, The Netherlands.|Center for Medical Sytems Biology, 2300 RC Leiden, The Netherlands.
authors: Cornelia M
authors: CM
authors: van Duijn
authors: Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Gonçalo R
authors: GR
authors: Abecasis
authors: Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
authors: Lude
authors: L
authors: Franke
authors: Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX1 2LU, UK.
authors: Timothy M
authors: TM
authors: Frayling
authors: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.|Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford OX3 7LJ, UK.|Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Trust, Oxford OX3 7LJ, UK.
authors: Mark I
authors: MI
authors: McCarthy
authors: Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia.|The University of Queensland Diamantina Institute, The Translation Research Institute, Brisbane 4012, Australia.
authors: Peter M
authors: PM
authors: Visscher
authors: Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University Hospital Essen, 45147 Essen, Germany.|Clinical Epidemiology, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, 07743 Jena, Germany.
authors: André
authors: A
authors: Scherag
authors: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.|Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.|Department of Human Genetics, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Cristen J
authors: CJ
authors: Willer
authors: Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Michael
authors: M
authors: Boehnke
authors: Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.
authors: Karen L
authors: KL
authors: Mohlke
authors: Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.|Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
authors: Cecilia M
authors: CM
authors: Lindgren
authors: Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland.|Department of Medical Genetics, University of Lausanne, Lausanne 1005, Switzerland.|Service of Medical Genetics, CHUV University Hospital, 1011 Lausanne, Switzerland.
authors: Jacques S
authors: JS
authors: Beckmann
authors: Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.|University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 OQQ, UK.|NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 OQQ, UK.
authors: Inês
authors: I
authors: Barroso
authors: Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.|Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
authors: Kari E
authors: KE
authors: North
authors: Science for Life Laboratory, Uppsala University, Uppsala 75185, Sweden.|Department of Medical Sciences, Molecular Epidemiology, Uppsala University, Uppsala 75185, Sweden.|Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
authors: Erik
authors: E
authors: Ingelsson
authors: Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.|Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA.|Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
authors: Joel N
authors: JN
authors: Hirschhorn
authors: MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.|The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.|The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.|The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
authors: Ruth J F
authors: RJF
authors: Loos
authors: Department of Internal Medicine, Division of Gastroenterology, and Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors: Elizabeth K
authors: EK
authors: Speliotes
mesh_terms: D050156:Adipogenesis / Q000235:genetics; D050154:Adiposity / Q000235:genetics; D000367:Age Factors; D015992:Body Mass Index; D004734:Energy Metabolism / Q000235:genetics; D005060:Europe / Q000208:ethnology; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D055106:Genome-Wide Association Study; D018698:Glutamic Acid / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D008297:Male; D009765:Obesity / Q000235:genetics* / Q000378:metabolism*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D040641:Quantitative Trait Loci / Q000235:genetics; D044469:Racial Groups / Q000235:genetics; D013569:Synapses / Q000378:metabolism
chemical_list: D007328:Insulin; D018698:Glutamic Acid