title: Management of perianal fistulas in Crohn's disease: an up-to-date review.
abstract: Perianal disease is one of the most disabling manifestations of Crohn's disease. A multidisciplinary approach of gastroenterologist, colorectal surgeon and radiologist is necessary for its management. A correct diagnosis, based on endoscopy, magnetic resonance imaging, endoanal ultrasound and examination under anesthesia, is crucial for perianal fistula treatment. Available medical and surgical therapies are discussed in this review, including new local treatment modalities that are under investigation.
authors: Manuela Marzo, Carla Felice, Daniela Pugliese, Gianluca Andrisani, Giammarco Mocci, Alessandro Armuzzi, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
authors: Manuela
authors: M
authors: Marzo
authors: Manuela Marzo, Carla Felice, Daniela Pugliese, Gianluca Andrisani, Giammarco Mocci, Alessandro Armuzzi, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
authors: Carla
authors: C
authors: Felice
authors: Manuela Marzo, Carla Felice, Daniela Pugliese, Gianluca Andrisani, Giammarco Mocci, Alessandro Armuzzi, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
authors: Daniela
authors: D
authors: Pugliese
authors: Manuela Marzo, Carla Felice, Daniela Pugliese, Gianluca Andrisani, Giammarco Mocci, Alessandro Armuzzi, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
authors: Gianluca
authors: G
authors: Andrisani
authors: Manuela Marzo, Carla Felice, Daniela Pugliese, Gianluca Andrisani, Giammarco Mocci, Alessandro Armuzzi, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
authors: Giammarco
authors: G
authors: Mocci
authors: Manuela Marzo, Carla Felice, Daniela Pugliese, Gianluca Andrisani, Giammarco Mocci, Alessandro Armuzzi, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
authors: Alessandro
authors: A
authors: Armuzzi
authors: Manuela Marzo, Carla Felice, Daniela Pugliese, Gianluca Andrisani, Giammarco Mocci, Alessandro Armuzzi, Luisa Guidi, IBD Unit, Complesso Integrato Columbus, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
authors: Luisa
authors: L
authors: Guidi
mesh_terms: D003131:Combined Modality Therapy; D003424:Crohn Disease / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D003952:Diagnostic Imaging / Q000379:methods; D006801:Humans; D011237:Predictive Value of Tests; D012003:Rectal Fistula / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D012307:Risk Factors; D016896:Treatment Outcome
keywords: Crohn’s disease; Drug therapy; Perianal fistula; Surgery; Tumor necrosis factor alpha