title: Electrochemical DNA hybridization sensors based on conducting polymers.
abstract: Conducting polymers (CPs) are a group of polymeric materials that have attracted considerable attention because of their unique electronic, chemical, and biochemical properties. This is reflected in their use in a wide range of potential applications, including light-emitting diodes, anti-static coating, electrochromic materials, solar cells, chemical sensors, biosensors, and drug-release systems. Electrochemical DNA sensors based on CPs can be used in numerous areas related to human health. This review summarizes the recent progress made in the development and use of CP-based electrochemical DNA hybridization sensors. We discuss the distinct properties of CPs with respect to their use in the immobilization of probe DNA on electrode surfaces, and we describe the immobilization techniques used for developing DNA hybridization sensors together with the various transduction methods employed. In the concluding part of this review, we present some of the challenges faced in the use of CP-based DNA hybridization sensors, as well as a future perspective.
authors: Nanotechnology Research Center and Department of Applied Life Science, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea. mahbub1982@kku.ac.kr.
authors: Md Mahbubur
authors: MM
authors: Rahman
authors: Nanotechnology Research Center and Department of Applied Life Science, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea. xiaobo@kku.ac.kr.
authors: Xiao-Bo
authors: XB
authors: Li
authors: Nanotechnology Research Center and Department of Applied Life Science, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea. lopa@kku.ac.kr.
authors: Nasrin Siraj
authors: NS
authors: Lopa
authors: Center for Advanced Instrumentation, Korea Research Institute of Standards and Science (KRISS), Daejeon 305-340, Korea. sjahn@kriss.re.kr.
authors: Sang Jung
authors: SJ
authors: Ahn
authors: Nanotechnology Research Center and Department of Applied Life Science, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea. jjlee@kku.ac.kr.
authors: Jae-Joon
authors: JJ
authors: Lee
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D004247:DNA / Q000737:chemistry*; D004563:Electrochemistry; D006801:Humans; D009693:Nucleic Acid Hybridization; D011108:Polymers / Q000737:chemistry*
chemical_list: D011108:Polymers; D004247:DNA