title: Surgical treatment of glottic cancer: retrospective analysis of 192 cases in a multidisciplinary tertiary care centre in Pune, India.
abstract: OBJECTIVE
  A multidisciplinary team approach is required for the preservation of voice and appropriate management of glottic cancer. This study aimed to investigate the outcomes of surgically treated glottic cancers of all stages. All aspects of surgical management, such as laser cordectomy, partial laryngectomy, total laryngectomy with voice prosthesis, and salvage laryngectomy, conducted at a single tertiary care institute in India, were reviewed.
  
  
  METHODS
  A retrospective analysis of hospital records was performed for 192 glottic cancer patients who were surgically treated between 2003 and 2007.
  
  
  RESULTS
  Patients with tumour stages 1 or 2 glottic cancer treated with laser cordectomy had a local control rate of 85 per cent and five-year survival rate of 98.6 per cent. The findings suggest that the number of partial laryngectomies performed for stage 3 tumours is declining. Patients with a tumour stage 3 lesion with a fixed hemilarynx or a tumour stage 4 lesion, treated with total laryngectomy, were found to have a five-year survival rate of 61.6 per cent. Nodal status was significantly associated with five-year survival rate.
  
  
  CONCLUSIONS
  Surgery offers a viable five-year survival rate in glottic cancer patients.
authors: Division of Surgical Oncology,Deenanath Mangeshkar Hospital and Research Centre,Pune,India.
authors: D S
authors: DS
authors: Kelkar
authors: Division of Surgical Oncology,Deenanath Mangeshkar Hospital and Research Centre,Pune,India.
authors: S S
authors: SS
authors: Gandhi
authors: Department of Research,Deenanath Mangeshkar Hospital and Research Centre,Pune,India.
authors: G A
authors: GA
authors: Oka
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005931:Glottis / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D007194:India; D053208:Kaplan-Meier Estimate; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods; D053685:Laser Therapy / Q000379:methods; D008297:Male; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant / Q000379:methods; D012189:Retrospective Studies; D016879:Salvage Therapy / Q000379:methods; D015996:Survival Rate; D062606:Tertiary Care Centers; D016896:Treatment Outcome
keywords: Voice Prosthesis