title: The development of a highly photostable and chemically stable zwitterionic near-infrared dye for imaging applications.
abstract: A novel zwitterionic near-infrared (NIR) dye, ZWCC, has been designed and synthesized. It shows significantly enhanced photostability and chemical stability compared to the existing zwitterionic NIR dye. In addition, the feasibility of labeling ZWCC with biological ligands was investigated and used in live cell imaging applications.
authors: Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), 138667, Singapore.
authors: Dongdong
authors: D
authors: Su
authors: Chai Lean
authors: CL
authors: Teoh
authors: Animesh
authors: A
authors: Samanta
authors: Nam-Young
authors: NY
authors: Kang
authors: Sung-Jin
authors: SJ
authors: Park
authors: Young-Tae
authors: YT
authors: Chang
mesh_terms: D002470:Cell Survival; D015195:Drug Design; D004355:Drug Stability; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D007259:Infrared Rays; D061986:MCF-7 Cells; D057054:Molecular Imaging / Q000379:methods*; D010456:Peptides, Cyclic / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D010456:Peptides, Cyclic; C550210:cyclo(Arg-Gly-Asp-Tyr-Lys)