title: [Changes of the cytokines profile in patients with hydronephrosis and indicated operative treatment].
abstract: The pronounced dysbalance of the cytokines profiles in the blood of patients, suffering recurrent hydronephrosis, caused by pelvio-ureteric segment stenosis of various etiology and in different clinical course, in the inborn obstruction especially, was revealed on a 21th postoperative day, witnessing the existence of various ways of the stricture recurrence occurrence. As a prognostic criterion of risk of the recurrence occurrence there were proposed: a ratio of level of a tumor necrosis factor-alpha (TNF-alpha) to interleukin-10 (IL-10) level, and as an additional diagnostic criterion--the IL-17 level, as well as revealing of the inherited genesis of the disorder in a system of fibrillogenesis regulation--the IL-4 level.
authors: V I
authors: VI
authors: Savenkov
authors: S B
authors: SB
authors: Pavlov
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000097:blood / Q000151:congenital / Q000473:pathology / Q000601:surgery*; D016753:Interleukin-10 / Q000097:blood*; D020381:Interleukin-17 / Q000097:blood; D015847:Interleukin-4 / Q000097:blood; D007682:Kidney Pelvis / Q000002:abnormalities / Q000378:metabolism / Q000601:surgery*; D008297:Male; D011379:Prognosis; D012306:Risk; D014409:Tumor Necrosis Factor-alpha / Q000097:blood*; D014513:Ureter / Q000002:abnormalities / Q000378:metabolism / Q000601:surgery*
chemical_list: D015415:Biomarkers; C508609:IL10 protein, human; C508598:IL4 protein, human; D020381:Interleukin-17; D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10; D015847:Interleukin-4