title: Relationship between coronary artery disease and pulmonary arterial pressure in patients with chronic obstructive pulmonary disease.
abstract: The aim of the present study was to determine whether there is a relationship between coronary artery disease and pulmonary hypertension and whether pulmonary hypertension is an additional risk factor for the presence and extent of coronary artery disease in patients with chronic obstructive pulmonary disease. Patients diagnosed with chronic obstructive pulmonary disease and pulmonary hypertension, and undergone diagnostic coronary angiography for evaluation of suspected coronary artery disease constituted the study group. Patients were divided into two groups according to the presence or absence of coronary artery disease and compared for age, gender, accompanying chronic disease, and pulmonary function tests. A total of 95 patients were recruited in the study. Comparison of the groups revealed that two groups were significantly different on gender (p=0.029), presence of hypertension (p=0.027), and biomass (p=0.040). Correlation analysis of variables revealed that male gender (rs=0.224, p=0.029), hypertension (rs=0.227, p=0.07) were positively correlated with the presence of coronary artery disease. FEV1/FVC ratio (rs=-0.253, p=0.013) and sPAP (rs=-0.215, p=0.037) were negatively correlated with the presence of coronary artery disease. High prevalence of coronary artery disease in patients with pulmonary hypertension secondary to chronic obstructive pulmonary disease was found. However, no correlation between the presence and severity of coronary artery disease and pulmonary hypertension was detected.
authors: Department of Cardiology, Van Training and Research Hospital Van, Turkey.
authors: Muntecep
authors: M
authors: Asker
authors: Department of Chest Disease, Van Training and Research Hospital Van, Turkey.
authors: Selvi
authors: S
authors: Asker
authors: Department of Cardiology, Van Military Hospital Van, Turkey.
authors: Ugur
authors: U
authors: Kucuk
authors: Department of Cardiology, Van Training and Research Hospital Van, Turkey.
authors: Hilal Olgun
authors: HO
authors: Kucuk
authors: Department of Chest Disease, Sıtkı Kocman University, Faculty of Medicine Mugla, Turkey.
authors: Bulent
authors: B
authors: Ozbay
keywords: Coronary artery disease; chronic obstructive; hypertension; pulmonary; pulmonary disease