title: Impact of age on access site-related outcomes in 469,983 percutaneous coronary intervention procedures: Insights from the British Cardiovascular Intervention Society.
abstract: We investigate adoption of the TRA in different age groups and study the relationship between age and access site related outcomes in a national cohort of patients undergoing PCI in the UK. Previous studies have reported conflicting data on radial access site adoption between different age groups, with age an independent predictor of failure of procedures undertaken through the radial approach. Age and access site related outcomes (based on transradial (TRA) and transfemoral (TFA) access) were studied in 469,983 PCI procedures undertaken in the UK from 2006 to 2012 in the age groups; <60, 60-<70, 70-<80, and ≥80 in the British Cardiovascular Intervention Society database. We studied access site practice in 469,983 patients who underwent PCI procedures in the United Kingdom. TRA utilization increased from 17.5% to 65.6% in the age group <60, and 16.6% to 54.5% in the age group ≥80 between 2006 and 2012. TRA was independently associated with decreased 30-day mortality in all age groups (<60: OR 0.64; 95% CI 0.54-0.74, P < 0.0001; 60-<70: OR 0.65; 95% CI 0.57-75, P < 0.0001, 70-<80: OR 0.58 (0.52-0.65, P < 0.0001 and ≥80: OR 0.65 (0.57-0.73, P < 0.0001). Adoption of the TRA for PCI has occurred least in older patients in the UK despite similar associations between TRA use and decreased 30-day mortality observed in all age groups.
authors: Manchester Heart Centre, Manchester Royal Infirmary, Manchester, United Kingdom.|Cardiovascular Research Group, Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
authors: Simon G
authors: SG
authors: Anderson
authors: Department of Cardiology, University Hospital of North Staffordshire, Stoke-on-Trent, North Staffordshire, United Kingdom.
authors: Karim
authors: K
authors: Ratib
authors: Institute of Applied Health Sciences, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, Scotland, United Kingdom.
authors: Phyo K
authors: PK
authors: Myint
authors: Cardiovascular Research Group, Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
authors: Bernard
authors: B
authors: Keavney
authors: Cardiovascular Research Group, Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.
authors: Chun Shing
authors: CS
authors: Kwok
authors: Department of Cardiology, Freeman Hospital, Newcastle Upon Tyne and Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom.
authors: Azfar
authors: A
authors: Zaman
authors: Department of Cardiology, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom.
authors: Peter F
authors: PF
authors: Ludman
authors: Department of Cardiology, The James Cook University Hospital, Middlesbrough, United Kingdom.
authors: Mark A
authors: MA
authors: de Belder
authors: Department of Cardiology, University Hospital of North Staffordshire, Stoke-on-Trent, North Staffordshire, United Kingdom.
authors: James
authors: J
authors: Nolan
authors: Cardiovascular Research Group, Institute of Cardiovascular Sciences, University of Manchester, Manchester, United Kingdom.|Farr Institute, Institute of Population Health, University of Manchester, Manchester, United Kingdom.
authors: Mamas A
authors: MA
authors: Mamas
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000379:methods; D002406:Catheterization, Peripheral / Q000009:adverse effects / Q000379:methods*; D015331:Cohort Studies; D017023:Coronary Angiography / Q000009:adverse effects / Q000379:methods; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D016208:Databases, Factual; D005260:Female; D005263:Femoral Artery; D005500:Follow-Up Studies; D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000379:methods* / Q000401:mortality; D017534:Radial Artery; D012189:Retrospective Studies; D018570:Risk Assessment; D012955:Societies, Medical; D015996:Survival Rate; D016896:Treatment Outcome; D006113:United Kingdom
keywords: PCI; access site; age; outcomes