title: Bladder cancer: a disease ripe for major advances.
abstract: Despite high incidence rates and substantial financial burdens associated with the care of patients with bladder cancer, progress in bladder cancer management has been modest and no new therapeutic agents for bladder cancer have been approved over the past decades. Fortunately, a substantial improvement in our understanding of the biology of this disease has occurred owing to revolutionizing molecular analysis platforms and increased interest among physicians and scientists in bladder cancer. As a consequence, a number of promising novel therapeutic agents are in development and are expected to make their way into clinics in the near future. This review focuses on the unique aspects of current bladder cancer research that support the assertion that bladder cancer is a likely frontier for major advancements soon.
authors: Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.
authors: Jong Chul
authors: JC
authors: Park
authors: Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD.
authors: Noah M
authors: NM
authors: Hahn
mesh_terms: D000818:Animals; D035843:Biomedical Research; D002986:Clinical Trials as Topic; D004273:DNA, Neoplasm / Q000097:blood; D004195:Disease Models, Animal; D006801:Humans; D007167:Immunotherapy; D035683:MicroRNAs / Q000502:physiology; D058990:Molecular Targeted Therapy; D009360:Neoplastic Cells, Circulating; D011379:Prognosis; D012107:Research Design; D012109:Research Support as Topic; D001749:Urinary Bladder Neoplasms / Q000235:genetics / Q000473:pathology / Q000628:therapy*
chemical_list: D004273:DNA, Neoplasm; D035683:MicroRNAs