title: On-label and off-label drug use in the treatment of female infertility.
abstract: Female infertility affects millions of couples worldwide and is estimated to account for one-third of all cases of infertility. The purpose of this article is to review the uses of both off-label treatments and those approved by the US Food and Drug Administration for female infertility, by examining the mechanism of action, the side-effect profile, fetal anomaly risks, and contraindications for the various drugs.
authors: Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Carolinas Medical Center, Charlotte, North Carolina.
authors: Rebecca S
authors: RS
authors: Usadi
authors: Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Carolinas Medical Center, Charlotte, North Carolina. Electronic address: kathryn_merriam@med.unc.edu.
authors: Kathryn S
authors: KS
authors: Merriam
mesh_terms: D002996:Clomiphene / Q000627:therapeutic use; D004348:Drug Labeling; D011307:Drug Prescriptions / Q000592:standards / Q000706:statistics & numerical data; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use*; D006062:Gonadotropins / Q000819:agonists / Q000627:therapeutic use; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy*; D056687:Off-Label Use; D010062:Ovulation Induction / Q000379:methods; D011247:Pregnancy
chemical_list: D005300:Fertility Agents, Female; D006062:Gonadotropins; D002996:Clomiphene
keywords: Female infertility; medications for female infertility