title: Localized scleroderma: clinical spectrum and therapeutic update.
abstract: Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology. Recent studies show that the localized form may affect internal organs and have variable morbidity. Treatment should be started very early, before complications occur due to the high morbidity of localized scleroderma. In this review, we report the most important aspects and particularities in the treatment of patients diagnosed with localized scleroderma.
authors: University of São Paulo, São Paulo, SP, Brazil.
authors: Mariana Figueiroa
authors: MF
authors: Careta
authors: University of São Paulo, São Paulo, SP, Brazil.
authors: Ricardo
authors: R
authors: Romiti
mesh_terms: D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D012594:Scleroderma, Localized / Q000145:classification / Q000209:etiology / Q000473:pathology* / Q000628:therapy*; D012595:Scleroderma, Systemic / Q000473:pathology; D012867:Skin / Q000473:pathology*