title: Cardiac amyloidosis in a heart transplant patient - A case report and retrospective analysis of amyloidosis evolution.
abstract: Cardiac amyloidosis is a very rare cause of heart failure in heart transplant recipients but an important differential diagnosis in cases of progressive cardiac failure. We report a 72-year-old male patient with the diagnosis of senile systemic amyloidosis (SSA) in a transplanted heart 15 years after transplantation by the initial diagnosis of the dilated cardiomyopathy. Additionally performed immunohistochemical analysis with anti-transthyretin antibody of the cardiac biopsies of the last 15 years enabled the possibility to show the evolution of this disease with characteristic biphasic pattern.
authors: Institute of Pathology of the University Hospital RWTH Aachen, Aachen, Germany;
authors: Svetlana
authors: S
authors: Kintsler
authors: Institute of Pathology of the University Hospital RWTH Aachen, Aachen, Germany;
authors: Jörg
authors: J
authors: Jäkel
authors: Department of Cardiology, Pulmonology, Angiology and Internal Intensive Care Medicine of the University Hospital RWTH Aachen, Aachen, Germany;
authors: Vincent
authors: V
authors: Brandenburg
authors: Department of Cardiology, Pulmonology, Angiology and Internal Intensive Care Medicine of the University Hospital RWTH Aachen, Aachen, Germany;
authors: Katrin
authors: K
authors: Kersten
authors: Institute of Pathology of the University Hospital RWTH Aachen, Aachen, Germany;
authors: Ruth
authors: R
authors: Knuechel
authors: Institute of Pathology of the Christian-Albrechts-University Kiel, Kiel, Germany.
authors: Christoph
authors: C
authors: Röcken
keywords: ATTR amyloid; cardiac biopsy; heart transplantation; senile systemic amyloidosis