title: Partially Plexiform Neurofibroma of the Labia Minora and Clitoral Hood-A Prognostic Dilemma.
abstract: BACKGROUND
  Unlike solitary neurofibromas, neurofibromatosis type 1 (NF1 or von Recklinghausen disease) has been associated with an increased risk of malignancies. Differentiation between these 2 entities may not be straightforward.
  
  
  METHODS
  We present the exceptional case of a girl with one congenital plexiform neurofibroma of the labia minora and clitoral hood in whom the diagnosis NF1 could not been made. Although this presented a prognostic dilemma, we advised against a screening program for any of the malignancies associated with NF1. Still, long-term follow-up seems indicated for recurrence of the partially plexiform neurofibroma and a possible occurrence of malignant peripheral nerve sheath tumor.
authors: Department of 1Plastic and Reconstructive Surgery, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands; 2Department of Gynaecologic Oncology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands; and 3Department of Gynaecology and Obstetrics, Landeskrankenhaus Leoben-Eisenerz, Austria.
authors: Leonore M
authors: LM
authors: Wehmeijer
authors: J Joris
authors: JJ
authors: Hage
authors: Barbara
authors: B
authors: Eberz
authors: Marc
authors: M
authors: van Beurden
mesh_terms: D001317:Austria; D019080:Cafe-au-Lait Spots / Q000150:complications; D002648:Child; D002987:Clitoris / Q000473:pathology; D005260:Female; D006801:Humans; D018318:Neurofibroma, Plexiform / Q000150:complications / Q000151:congenital* / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D016896:Treatment Outcome; D014844:Vulva / Q000473:pathology / Q000601:surgery; D014846:Vulvar Neoplasms / Q000473:pathology* / Q000601:surgery