title: Plasmonic gold nanostars for multi-modality sensing and diagnostics.
abstract: Gold nanostars (AuNSs) are unique systems that can provide a novel multifunctional nanoplatform for molecular sensing and diagnostics. The plasmonic absorption band of AuNSs can be tuned to the near infrared spectral range, often referred to as the "tissue optical window", where light exhibits minimal absorption and deep penetration in tissue. AuNSs have been applied for detecting disease biomarkers and for biomedical imaging using multi-modality methods including surface-enhanced Raman scattering (SERS), two-photon photoluminescence (TPL), magnetic resonance imaging (MRI), positron emission tomography (PET), and X-ray computer tomography (CT) imaging. In this paper, we provide an overview of the recent development of plasmonic AuNSs in our laboratory for biomedical applications and highlight their potential for future translational medicine as a multifunctional nanoplatform.
authors: Fitzpatrick Institute for Photonics, Duke University, Durham, NC 27708, USA. yl183@duke.edu.|Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. yl183@duke.edu.|Department of Chemistry, Duke University, Durham, NC 27708, USA. yl183@duke.edu.
authors: Yang
authors: Y
authors: Liu
authors: Fitzpatrick Institute for Photonics, Duke University, Durham, NC 27708, USA. hkscott1125@gmail.com.|Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. hkscott1125@gmail.com.
authors: Hsiangkuo
authors: H
authors: Yuan
authors: Department of Radiology & Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, NC 27510, USA. fkersey@email.unc.edu.
authors: Farrell R
authors: FR
authors: Kersey
authors: Fitzpatrick Institute for Photonics, Duke University, Durham, NC 27708, USA. janna.register@duke.edu.|Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. janna.register@duke.edu.
authors: Janna K
authors: JK
authors: Register
authors: Department of Radiology & Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, NC 27510, USA. parrotmc@email.unc.edu.
authors: Matthew C
authors: MC
authors: Parrott
authors: Fitzpatrick Institute for Photonics, Duke University, Durham, NC 27708, USA. tuan.vodinh@duke.edu.|Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. tuan.vodinh@duke.edu.|Department of Chemistry, Duke University, Durham, NC 27708, USA. tuan.vodinh@duke.edu.
authors: Tuan
authors: T
authors: Vo-Dinh
mesh_terms: D015374:Biosensing Techniques; D003952:Diagnostic Imaging; D006046:Gold / Q000737:chemistry*; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D013059:Spectrum Analysis, Raman
chemical_list: D006046:Gold