title: Hb S/β+-thalassemia due to Hb sickle and a novel deletion of DNase I hypersensitive sites HS3 and HS4 of the β locus control region.
authors: Division of Hematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
authors: Ali
authors: A
authors: Amid
authors: Division of Hematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
authors: Melina
authors: M
authors: Cheong
authors: Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, Ontario, Canada.
authors: Barry
authors: B
authors: Eng
authors: Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, Ontario, Canada.
authors: Meredith
authors: M
authors: Hanna
authors: Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, Ontario, Canada.
authors: Betty-Ann
authors: BA
authors: Hohenadel
authors: Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, Ontario, Canada.
authors: Lisa M
authors: LM
authors: Nakamura
authors: Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, Ontario, Canada.
authors: Lynda
authors: L
authors: Walker
authors: Division of Hematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
authors: Isaac
authors: I
authors: Odame
authors: Division of Hematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
authors: Melanie
authors: M
authors: Kirby-Allen
authors: Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, Ontario, Canada Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada waye@hhsc.ca.
authors: John S
authors: JS
authors: Waye
mesh_terms: D000755:Anemia, Sickle Cell / Q000175:diagnosis / Q000235:genetics*; D001483:Base Sequence; D002648:Child; D002874:Chromosome Mapping; D056726:Genetic Association Studies; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006579:Heterozygote; D006801:Humans; D019901:Locus Control Region; D008297:Male; D008969:Molecular Sequence Data; D005810:Multigene Family; D009154:Mutation; D010641:Phenotype; D017384:Sequence Deletion; D055544:beta-Globins / Q000235:genetics*; D017086:beta-Thalassemia / Q000175:diagnosis / Q000235:genetics*
chemical_list: D006451:Hemoglobin, Sickle; D055544:beta-Globins
keywords: DNase I hypersensitive sites; Hb S/β+-thalassemia; locus control region; novel deletion