title: An intimate view of a spliceosome component.
abstract: A high-resolution structure reveals how the ribonucleoprotein particle called U1 snRNP engages with 5' splice sites.
authors: Center for RNA Molecular Biology, Case Western Reserve University, Cleveland, United States.
authors: Timothy W
authors: TW
authors: Nilsen
mesh_terms: D006801:Humans; D022821:RNA Splice Sites; D017412:Ribonucleoprotein, U1 Small Nuclear / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D022821:RNA Splice Sites; D017412:Ribonucleoprotein, U1 Small Nuclear
keywords: 5′ splice site; U1 snRNP; biophysics; crystallography; human; pre-mRNA splicing; spliceosome; structural biology