title: Aquagenic wrinkling of the palms: morphological changes in reflectance confocal microscopy and high-definition optical coherence tomography.
abstract: Aquagenic wrinkling of the palms (AWP) is a rare condition, which is characterized by appearance of whitish papules and plaques, and an excessive wrinkling and swelling of the palmar skin after exposure to water. In most cases, young women are affected, and an association of AWP with cystic fibrosis (CF) has been surmised. We report on two cases of AWP, which were not related to CF, in whom we used two innovative imaging techniques, namely high-definition optical coherence tomography and reflectance confocal microscopy, to show in vivo skin changes occurring after exposure of the skin to tap water in comparison to the findings in a healthy control person.
authors: Department of Dermatology and Allergology, Ludwig Maximilian University of Munich, Munich, Germany.
authors: Lea
authors: L
authors: Bielicky
authors: Markus
authors: M
authors: Braun-Falco
authors: Thomas
authors: T
authors: Ruzicka
authors: Tanja
authors: T
authors: Maier
mesh_terms: D000328:Adult; D005260:Female; D006225:Hand; D006801:Humans; D007645:Keratoderma, Palmoplantar / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology*; D018613:Microscopy, Confocal; D011859:Radiography; D012867:Skin / Q000000981:diagnostic imaging / Q000473:pathology; D015595:Skin Aging / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014867:Water / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D014867:Water