title: Association between physical fitness, quality of life, and depression in stage II-III colorectal cancer survivors.
abstract: The impact of cancer on quality of life and depression is an important issue. The purpose of this study was to identify the impact of physical fitness on quality of life and depression in stage II-III colorectal cancer survivors.
  
  
  
  Participants in the current study included 122 stage II-III colorectal cancer survivors (57 females; 56.67 ± 9.16 years of age and 55 males; 54.69 ± 9.78 years of age). Fitness was assessed using the 6-min walk test, chair stand test, and push-up test. Quality of life and depression were measured using the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) scale and a 9-item patient health questionnaire interview, respectively.
  
  
  
  There was a significant association between physical fitness and quality of life and depression in colorectal cancer survivors. The 6-min walk test results were associated with FACT-C total (r = 0.298, p < 0.05), physical well-being (r = 0.230, p < 0.05), functional well-being (r = 0.234, p < 0.05), colorectal cancer concern (r = 0.229, p < 0.05), and depression (r = -0.228, p < 0.05), and the chair stand test results were associated with functional well-being (r = 0.231, p < 0.05), colorectal cancer concern (r = 0.242, p < 0.05), and depression (r = -0.227, p < 0.05) even after controlling for all potentially confounding variables. A multiple regression analysis indicated that the 6-min walk was a significant predictor of health-related quality of life, and participants in the lowest tertile of the 6-min walk test results had lower quality of life and greater depression than those in the highest tertile.
  
  
  
  Improving and maintaining physical fitness are important for quality of life and depression in stage II-III colorectal cancer survivors.
authors: Department of Sport and Leisure Studies, Yonsei University, 134 Seodaemun-Gu, Shinchon-Dong, Seoul, Korea, 120-749.
authors: Junga
authors: J
authors: Lee
authors: Mikyung
authors: M
authors: Lee
authors: Sunghyun
authors: S
authors: Hong
authors: Ji Young
authors: JY
authors: Kim
authors: Hyuna
authors: H
authors: Park
authors: Minsuk
authors: M
authors: Oh
authors: Hyuk In
authors: H
authors: Yang
authors: Dong-Woo
authors: DW
authors: Kang
authors: Jihye
authors: J
authors: Park
authors: Dong-Il
authors: DI
authors: Kim
authors: Sanghee
authors: S
authors: Chu
authors: Jiwon
authors: J
authors: Lee
authors: Hyuk
authors: H
authors: Hur
authors: Nam Kyu
authors: NK
authors: Kim
authors: Justin Y
authors: JY
authors: Jeon
mesh_terms: D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000473:pathology / Q000503:physiopathology* / Q000523:psychology*; D003863:Depression / Q000209:etiology* / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010809:Physical Fitness; D011788:Quality of Life; D011795:Surveys and Questionnaires; D017741:Survivors