title: Wound-related complications and clinical outcomes following open globe injury repair.
abstract: BACKGROUND
  Careful surgical management of traumatic wounds is important in open globe injury repair. This study examines the clinical outcomes following repair of open globe injuries with particular focus on wound-related issues.
  
  
  METHODS
  Retrospective, cohort study of consecutive open globe injuries presenting to a tertiary referral eye hospital from 1 January 2009 to 31 December 2011.
  
  
  METHODS
  A total of 267 eyes of 263 patients, mainly male (82.5%) with a mean age of 44.8 (range: 4-97) years. Average follow up was 6.9 months.
  
  
  METHODS
  All cases classified according to Ocular Trauma Classification Group.
  
  
  METHODS
  Visual outcomes, risk factors for and rates of postoperative complications and endophthalmitis.
  
  
  RESULTS
  There were 83 globe ruptures, 182 penetrating and 2 perforating eye injuries, of which 43 cases had intraocular foreign body. Factors contributing to final visual acuity (VA) <6/60 were poor presenting VA (odds ratio [OR] = 16.0, 95% confidence interval [CI]: 4.81-53.1), globe rupture (OR = 4.64, [1.99-10.8]), retinal detachment (OR = 3.40, [1.19-9.74]) and age ≥50 (OR = 2.45, [1.05-5.74]). Wound leak occurred in 44 eyes (16%). Of these, 18 (41%) proceeded to re-suturing. Factors contributing to wound leak were stellate-shaped wound (OR = 3.28, [1.39-7.73]) and delayed presentation (OR = 2.80, [1.02-7.71]). Ten eyes (3.7%) developed endophthalmitis. Factors associated with endophthalmitis were delayed presentation (OR = 8.91, [1.71-46.6]), microbial keratitis (OR = 12.5, [1.85-85.0]) and lens capsule breach (OR = 12.4, [1.85-83.1]).
  
  
  CONCLUSIONS
  Wound leak is an important postoperative complication of open globe injury repair. Delayed presentation is an important risk factor for postoperative wound leak and endophthalmitis. Prompt and meticulous wound management of open globe injury may reduce these complications.
authors: Vitreoretinal Unit, The Royal Victorian Eye and Ear Hospital, Melbourne, Victoria.|Clinical Research Department, Centre for Eye Research Australia, Melbourne, Victoria.
authors: George Y X
authors: GY
authors: Kong
authors: Vitreoretinal Unit, The Royal Victorian Eye and Ear Hospital, Melbourne, Victoria.
authors: Robert H
authors: RH
authors: Henderson
authors: Vitreoretinal Unit, The Royal Victorian Eye and Ear Hospital, Melbourne, Victoria.|Clinical Research Department, Centre for Eye Research Australia, Melbourne, Victoria.|Department of Ophthalmology, The University of Melbourne, Melbourne, Victoria.
authors: Sukhpal S
authors: SS
authors: Sandhu
authors: Vitreoretinal Unit, The Royal Victorian Eye and Ear Hospital, Melbourne, Victoria.|Academic Unit of Ophthalmology, Australian National University, Canberra, Australian Capital Territory, Australia.
authors: Rohan W
authors: RW
authors: Essex
authors: Vitreoretinal Unit, The Royal Victorian Eye and Ear Hospital, Melbourne, Victoria.|Clinical Research Department, Centre for Eye Research Australia, Melbourne, Victoria.|Department of Ophthalmology, The University of Melbourne, Melbourne, Victoria.
authors: Penelope J
authors: PJ
authors: Allen
authors: Vitreoretinal Unit, The Royal Victorian Eye and Ear Hospital, Melbourne, Victoria.
authors: William G
authors: WG
authors: Campbell
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D065306:Corneal Injuries / Q000503:physiopathology / Q000601:surgery; D009877:Endophthalmitis / Q000209:etiology; D005129:Eye Foreign Bodies / Q000503:physiopathology / Q000601:surgery*; D015807:Eye Injuries, Penetrating / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D012590:Sclera / Q000293:injuries; D013529:Surgical Wound Dehiscence / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D014792:Visual Acuity / Q000502:physiology; D014945:Wound Healing / Q000502:physiology
keywords: endophthalmitis; open eye injury; penetrating eye injury; wound leak