title: WntversusHippo: A balanced act or dynamic duo?
abstract: The Hippo signaling pathway was first discovered in Drosophila as a conserved regulator of organ size. Genetic inactivation in mice demonstrates that the Hippo pathway functions as a fundamental inhibitor of organ growth during development, and as a critical tumor suppressor in epithelial tissues.
authors: Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60637, USA.
authors: Zhongliang
authors: Z
authors: Wang
authors: Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60637, USA.
authors: Jixing
authors: J
authors: Ye
authors: Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60637, USA.
authors: Youlin
authors: Y
authors: Deng
authors: Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60637, USA.
authors: Zhengjian
authors: Z
authors: Yan
authors: Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60637, USA.
authors: Sahitya
authors: S
authors: Denduluri
authors: Molecular Oncology Laboratory, The University of Chicago Medical Center, Chicago, IL 60637, USA.
authors: Tong-Chuan
authors: TC
authors: He
keywords: Destruction complex; Hippo; Proteasome degradation; Signal transduction; Wnt/β-catenin; YAP/TAZ; β-TrCP