title: Luminescent probes for the bioimaging of small anionic species in vitro and in vivo.
abstract: The ability to spatiotemporally identify the formation of specific anionic species, or track changes in their concentration inside living systems, is of critical importance in deciphering their exact biological roles and effects. The development of probes (also called bioimaging agents and intracellular sensors) to achieve this goal has become a rapidly growing branch of supramolecular chemistry. In this critical review the challenges specific to the task are identified and for a select range of small anions of environmental and biological relevance (fluoride, chloride, iodide, cyanide, pyrophosphate, bicarbonate, hydrosulphide, peroxynitrite, hypochlorite and hypobromite) a comprehensive overview of the currently available in vitro and in vivo probes is provided.
authors: Centre for Chemistry and Biotechnology, School of Life and Environmental Sciences, Deakin University, Pigdons Rd, Waurn Ponds, Victoria, Australia. fred.pfeffer@deakin.edu.au.
authors: Trent D
authors: TD
authors: Ashton
authors: Katrina A
authors: KA
authors: Jolliffe
authors: Frederick M
authors: FM
authors: Pfeffer
mesh_terms: D000818:Animals; D000838:Anions / Q000032:analysis*; D017173:Caenorhabditis elegans / Q000737:chemistry; D002460:Cell Line; D005456:Fluorescent Dyes; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D057054:Molecular Imaging / Q000379:methods*
chemical_list: D000838:Anions; D005456:Fluorescent Dyes