title: Effect of Letrozole on endometriosis-related pelvic pain.
abstract: BACKGROUND
  To determine the role of Letrozole, an aromatase inhibitor, in the treatment of endometriotic pain.
  
  
  METHODS
  In this prospective, randomized, controlled clinical trial in minimally invasive surgery research center, 51 women with pelvic endometriosis and endometriotic pain (dyspareunia, dysmenorrhea, pelvic pain) score of 5 or more (for at least one of these endometriotic pain), after laparoscopic diagnosis and conservative laparoscopic surgery were treated with either Letrozole plus OCP (n=25) or only OCP (n=26) for 4 months continuously.
  
  
  RESULTS
  Using VAS test, the score of dyspareunia, dysmenorrhea and pelvic pain 4 months after the laparoscopic surgery declined significantly in both groups but the difference between results of the two groups was not significant.
  
  
  CONCLUSIONS
  Both treatment modalities showed comparable effectiveness in the treatment of pains related to endometriosis and in comparison with OCP, Letrozole did not affect the outcome.
authors: 1. Associate Professor, Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Department of gynecology and obstetrics, Rasool Akram Hospital, Tehran, Iran. dralmassi@yahoo.com.
authors: Fariba
authors: F
authors: Almassinokiani
authors: 2. Assistant Professor, Iran University of Medical Sciences, Firoozgar Hospital, Tehran, Iran. a_almasi_n@hotmail.com.
authors: Alireza
authors: A
authors: Almasi
authors: 3. Medical Student, Tehran University of Medical Sciences, Department of gynecology and obstetrics, Rasool Akram Hospital, Tehran, Iran. thekingofkings_angle@yahoo.com.
authors: Peyman
authors: P
authors: Akbari
authors: 4. Resident of Gynecology, Iran University of Medical Sciences, Department of Gynecology and Obstetrics, Rasool Akram Hospital, Tehran, Iran. msaberi@hyhoo.com.
authors: Mahboubeh
authors: M
authors: Saberifard
keywords: Aromatase inhibitor; Endometriosis; Letrozole; Pelvic pain