title: A H+/Ag+ dual-target responsive label-free light-up probe based on a DNA triplex.
abstract: We developed a dual-target responsive sensor for label-free light-up fluorescent detection of protons (H(+)) and silver ions (Ag(+)) using an "OR'' logic gate. Berberine, a cost-effective and non-toxic indicator, partially intercalates the formed triplex DNA in the presence of H(+) or Ag(+), generating enhanced fluorescence. The designed Ag(+) probe has high selectivity and desirable sensitivity, which is necessary for practical use. The robust "OR" logic gate is capable of a rapid and reversible response to the H(+) and/or Ag(+) inputs.
authors: Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Collaborative Innovation Center of Suzhou Nano Science and Technology, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123 (P.R. China); Department of Chemistry, Zhengzhou University, Zhengzhou, 450001 (P.R. China).
authors: Lijun
authors: L
authors: Xu
authors: Yahui
authors: Y
authors: Guo
authors: Jine
authors: J
authors: Wang
authors: Lu
authors: L
authors: Zhou
authors: Yuanyuan
authors: Y
authors: Zhang
authors: Shanni
authors: S
authors: Hong
authors: Zhili
authors: Z
authors: Wang
authors: Jianye
authors: J
authors: Zhang
authors: Renjun
authors: R
authors: Pei
mesh_terms: D004247:DNA / Q000138:chemical synthesis / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006859:Hydrogen / Q000032:analysis*; D008027:Light; D012834:Silver / Q000032:analysis*; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D012834:Silver; D006859:Hydrogen; D004247:DNA
keywords: berberine; light-up probe; logic gate; silver; triplex DNA