title: Diagnostic value of combined parameters derived from ambulatory electrocardiography for detecting coronary artery disease in non-active chest pain patients.
abstract: OBJECTIVE
  The diagnostic value of ST-segment deviation detected by ambulatory electrocardiography (AECG) is controversial in identifying coronary artery disease (CAD) referred for coronary angiography (CAG). Recently, many parameters which evaluate CAD can be derived from AECG. Therefore, we aimed to investigate the diagnostic value of AECG in screening CAD referred for CAG when several parameters were combined.
  
  
  METHODS
  We studied the 104 chest pain inpatients. All patients received the CAG and AECG. A lumen diameter reduction of ≥ 50% was considered CAD according to CAG. The parameters derived from AECG included ST-segment deviation, apnea hypopnea index (AHI), QT interval dispersion (QTd) and heart rate variability (HRV). The diagnostic value of AECG in screening CAD was evaluated.
  
  
  RESULTS
  Of the 104 patients, 57 (54.8%) had CAD according to CAG. The sensitivity of ST-segment deviation in screening CAD was 64.9%; the specificity was 89.4%; and the Kappa value was 0.528. The sensitivity of at least three combined parameters including ST-segment deviation, AHI, QTd and HRV was 89.5%; the specificity was 87.2%; and the Kappa value was 0.767.
  
  
  CONCLUSIONS
  AECG is very useful in screening CAD referred for CAG, especially while several parameters including ST-segment deviation, AHI, HRV and QTd are combined.
authors: Yue Jiang, Department of Cardiology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.
authors: Yue
authors: Y
authors: Jiang
authors: Jun-Ping Tian, Department of Cardiology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.
authors: Jun-Ping
authors: JP
authors: Tian
authors: Hong Wang, Department of Endocrinology, Aerospace Central Hospital, Beijing, China.
authors: Hong
authors: H
authors: Wang
authors: Bu-Xing Chen, Department of Cardiology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.
authors: Bu-Xing
authors: BX
authors: Chen
authors: Feng-He Du, Department of Cardiology, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.
authors: Feng-He
authors: FH
authors: Du
keywords: Ambulatory electrocardiography; Apnea hypopnea index; Heart rate variability; QT interval dispersion; ST-segment deviation