title: Hedgehog Expression During Development and Regeneration in the Hemichordate, Ptychodera flava.
abstract: Hedgehog is a toolkit gene conserved in metazoans. However, its function differs among taxa, and it shows versatile expression patterns in morphogenesis. We analyzed the expression pattern of hedgehog in the indirect development of the hemichordate, Ptychodera flava, during development and regeneration. Pf-Hh showed distinct enteropneust-specific expression at the anterior tip of the larvae, as well as deuterostome-conserved expression in the pharyngeal endoderm. In contrast, the gene is expressed only in the pharyngeal region during anterior regeneration, but not in the anterior tip of the proboscis. These data suggest that anterior regeneration is driven not only by conserved developmental mechanisms, but also by some regeneration-specific mechanism(s).
authors: Marine Biological Laboratory, Graduate School of Science, Hiroshima University, Onomichi, Hiroshima 722-00073, Japan.
authors: Asuka
authors: A
authors: Arimoto
authors: Kuni
authors: K
authors: Tagawa
mesh_terms: D000818:Animals; D002816:Chordata, Nonvertebrate / Q000254:growth & development* / Q000502:physiology; D003001:Cloning, Molecular; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D053823:Hedgehog Proteins / Q000235:genetics / Q000378:metabolism*; D010802:Phylogeny
chemical_list: D053823:Hedgehog Proteins
keywords: Ptychodera flava; acorn worm; development; gene expression; hedgehog; hemichordate; regeneration