title: Subcutaneously administered antibiotics: a national survey of current practice from the French Infectious Diseases (SPILF) and Geriatric Medicine (SFGG) society networks.
abstract: A national survey was performed to explore antibiotic prescription by the subcutaneous (sc) route among French infectious diseases and geriatric practitioners. Among the participating physicians, 367 (96.1%) declared administering sc antibiotics at some point. Ceftriaxone was prescribed sc by all but one, and ertapenem, teicoplanin, aminoglycosides and amoxicillin by 33.2%, 39.2%, 35.1% and 15.3%, respectively. The sc route was resorted to mainly in case of unavailable oral, intravenous or intramuscular routes, especially during palliative care. Pain, skin necrosis and lack of efficacy were the main adverse effects, reported by 70.8%, 12.8% and 19.9% of practitioners, respectively. Further studies are needed to precise the indications, modalities and tolerance of sc antibiotic use.
authors: Service de Maladies Infectieuses, Centre Hospitalier, Chambéry, France. Electronic address: emmanuel.forestier@ch-chambery.fr.
authors: E
authors: E
authors: Forestier
authors: Service de Gériatrie, Centre Hospitalier Universitaire, Poitiers, France.
authors: M
authors: M
authors: Paccalin
authors: Pole de Gérontologie clinique, Centre Hospitalier Universitaire, Bordeaux, France.
authors: C
authors: C
authors: Roubaud-Baudron
authors: Service de Gériatrie, Centre Hospitalier, Alès, France.
authors: T
authors: T
authors: Fraisse
authors: Service de Gériatrie, Centre Hospitalier Universitaire, Grenoble, France.
authors: G
authors: G
authors: Gavazzi
authors: Service de Maladies Infectieuses, Centre Hospitalier, Annecy, France.
authors: J
authors: J
authors: Gaillat
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000009:adverse effects; D003141:Communicable Diseases / Q000188:drug therapy*; D005602:France; D006801:Humans; D007279:Injections, Subcutaneous / Q000009:adverse effects; D009336:Necrosis / Q000139:chemically induced / Q000453:epidemiology; D010146:Pain / Q000139:chemically induced / Q000453:epidemiology; D011795:Surveys and Questionnaires
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotics; ceftriaxone; ertapenem; subcutaneous; teicoplanin