title: Complete genome sequence of Streptomyces lividans TK24.
abstract: Streptomyces lividans TK24 is the standard host for the heterologous expression of a number of different proteins and antibiotic-synthesizing enzymes. As such, it is often used as an experimental microbial cell factory for the production of secreted heterologous proteins including human cytokines and industrial enzymes, and of several antibiotics. It accepts methylated DNA and is an ideal Streptomyces cloning system. Here, we report the complete genome sequence of S. lividans TK24 that includes a plasmid-less genome of 8.345Mbp (72.24% G+C content).
authors: Center for Biotechnology (CeBiTec), Universität Bielefeld, Bielefeld, Germany.
authors: Christian
authors: C
authors: Rückert
authors: Center for Biotechnology (CeBiTec), Universität Bielefeld, Bielefeld, Germany.
authors: Andreas
authors: A
authors: Albersmeier
authors: Center for Biotechnology (CeBiTec), Universität Bielefeld, Bielefeld, Germany.
authors: Tobias
authors: T
authors: Busche
authors: Center for Biotechnology (CeBiTec), Universität Bielefeld, Bielefeld, Germany.
authors: Sebastian
authors: S
authors: Jaenicke
authors: Center for Biotechnology (CeBiTec), Universität Bielefeld, Bielefeld, Germany.
authors: Anika
authors: A
authors: Winkler
authors: Matís, Vínlandsleið 12, 113 Reykjavík, Iceland.
authors: Ólafur H
authors: ÓH
authors: Friðjónsson
authors: Matís, Vínlandsleið 12, 113 Reykjavík, Iceland.
authors: Guðmundur Óli
authors: GÓ
authors: Hreggviðsson
authors: BioXpr SA, B-5000 Namur, Belgium.
authors: Christophe
authors: C
authors: Lambert
authors: GlaxoSmithKline, 315 Cambridge Science Park, Cambridge CB4 0WG, UK.
authors: Daniel
authors: D
authors: Badcock
authors: Chemical and Biochemical Process Technology and Control Section (BioTeC), Department of Chemical Engineering, KU Leuven, Belgium.
authors: Kristel
authors: K
authors: Bernaerts
authors: Laboratory of Molecular Bacteriology, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium. Electronic address: jozef.anne@rega.kuleuven.be.
authors: Jozef
authors: J
authors: Anne
authors: Laboratory of Molecular Bacteriology, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium; Institute of Molecular Biology and Biotechnology-FoRTH and Department of Biology-University of Crete, Iraklio, Crete, Greece. Electronic address: tassos.economou@rega.kuleuven.be.
authors: Anastassios
authors: A
authors: Economou
authors: Center for Biotechnology (CeBiTec), Universität Bielefeld, Bielefeld, Germany. Electronic address: joern.kalinowski@cebitec.uni-bielefeld.de.
authors: Jörn
authors: J
authors: Kalinowski
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics; D016680:Genome, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data; D013302:Streptomyces / Q000235:genetics; D048170:Streptomyces lividans / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins
keywords: Genome sequence; Heterologous protein expression; Model organism; Streptomyces