title: Synthesis of a temperature-sensitive matrine-imprinted polymer and its potential application for the selective extraction of matrine from radix Sophorae tonkinensis.
abstract: A temperature-sensitive matrine-imprinted polymer was prepared in chloroform by free-radical cross-linking copolymerization of methacrylic acid at 60 °C in the presence of ethylene glycol dimethacrylate as the cross-linker, N-isopropyl acrylamide as the temperature-responsive monomer and matrine as the template molecule. Binding experiments and Scatchard analyses revealed that two classes of binding sites were formed on molecular imprinted polymer (MIP) at 50 °C. Additionally, the thermoresponsive MIP was tested for its application as a sorbent material for the selective separation of matrine from Chinese medicinal plant radix Sophorae tonkinensis. It was shown that the thermoresponsive MIP displayed different efficiency in clean-up and enrichments using the SPE protocol at different temperatures.
authors: School of Chemistry and Chemical Engineering, Guangxi University, 100 Daxue Road, Nanning 530004, China. jmj247742311@gmail.com.
authors: Minjie
authors: M
authors: Jiang
authors: School of Chemistry and Chemical Engineering, Guangxi University, 100 Daxue Road, Nanning 530004, China. jiangminjietp@outlook.com.
authors: Lisheng
authors: L
authors: Wang
authors: School of Chemistry and Chemical Engineering, Guangxi University, 100 Daxue Road, Nanning 530004, China. wendaoliuxu@163.com.
authors: Xu
authors: X
authors: Liu
authors: School of Chemistry and Chemical Engineering, Guangxi University, 100 Daxue Road, Nanning 530004, China. yanghua6316@sina.com.
authors: Hua
authors: H
authors: Yang
authors: School of Chemistry and Chemical Engineering, Guangxi University, 100 Daxue Road, Nanning 530004, China. fancyren@163.com.
authors: Fan
authors: F
authors: Ren
authors: School of Pharmaceutical, Guangxi Medical University, 22 Shuangyong Road, Nanning 530021, China. welldone.123@163.com.
authors: Lizhen
authors: L
authors: Gan
authors: School of Pharmaceutical, Guangxi Medical University, 22 Shuangyong Road, Nanning 530021, China. welldone.123@163.com.
authors: Weizhe
authors: W
authors: Jiang
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D054802:Molecular Imprinting; D015394:Molecular Structure; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D011807:Quinolizines / Q000737:chemistry*; D029909:Sophora / Q000737:chemistry*; D013696:Temperature; D000093842:Matrines
chemical_list: D000470:Alkaloids; D011108:Polymers; D011807:Quinolizines; D000093842:Matrines