title: Reaction between a haemoglobin model compound and hydrosulphide in aqueous solution.
abstract: The reaction between hydrosulphide (SH(-)) and a haemoglobin model compound, composed of a Fe(III)-porphyrin and a cyclodextrin dimer possessing a pyridine-linker (met-hemoCD3), was studied. Met-hemoCD3 formed a stable (SH(-))-met-hemoCD3 complex in oxygen-free neutral aqueous solution. In the presence of O2, reversible ligand exchange between (SH(-))-met-hemoCD3 (Fe(III)) and O2-hemoCD3 (Fe(II)) occurred.
authors: Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan. kwatanabe@phar.kyushu-u.ac.jp.
authors: Kenji
authors: K
authors: Watanabe
authors: Toshikane
authors: T
authors: Suzuki
authors: Hiroaki
authors: H
authors: Kitagishi
authors: Koji
authors: K
authors: Kano
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry; D019281:Dimerization; D006454:Hemoglobins / Q000737:chemistry*; D006862:Hydrogen Sulfide / Q000737:chemistry*; D008665:Metalloporphyrins / Q000737:chemistry; D012996:Solutions; D014867:Water / Q000737:chemistry*
chemical_list: D003505:Cyclodextrins; D006454:Hemoglobins; D008665:Metalloporphyrins; D012996:Solutions; D014867:Water; D006862:Hydrogen Sulfide