title: Haematidrosis associated with epilepsy in a girl successfully treated with oxcarbazepine: case report.
abstract: The aetiology and pathological mechanisms involved in the development of haematidrosis (bloody sweat) remain unclear. There is no specific treatment for this disorder. This case report describes the clinical manifestations and treatment of a 9-year-old female with haematidrosis associated with epilepsy. The diagnosis of haematidrosis was confirmed by medical personnel who observed the bleeding and were able to rule out other causes of the bloody exudate. The episodes of bleeding were spontaneous, transient, and self-limited. Smears of the bloody exudate contained all of the components of peripheral blood. A skin biopsy taken at one site of the bloody exudate was normal, showing no signs of blood extravasation or bleeding sweat glands. The bleeding events were found to be immediately preceded by tonic seizures. An electroencephalogram indicated cerebral parietooccipital epilepsy, which was characterized by an intermittent medium-high amplitude θ rhythm (5-7 Hz) with a few spikes. The symptoms of both epilepsy and haematidrosis resolved after treatment with the antiepileptic drug 150 mg oxcarbazepine, orally, twice a day, which suggests that the epileptic seizures triggered haematidrosis in this patient.
authors: Department of Haematology, PLA 100th Hospital, Suzhou, Jiangsu Province, China.
authors: Hongshi
authors: H
authors: Shen
authors: Innovation Centre of Haematology and the Key Laboratory of Thrombosis and Haemostasis of the Ministry of Health, Jiangsu Institute of Haematology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China zwang11@sina.com.
authors: Zhaoyue
authors: Z
authors: Wang
authors: Department of Haematology, PLA 100th Hospital, Suzhou, Jiangsu Province, China.
authors: Tianqin
authors: T
authors: Wu
authors: Department of Haematology, PLA 100th Hospital, Suzhou, Jiangsu Province, China.
authors: Jing
authors: J
authors: Wang
authors: Department of Haematology, PLA 100th Hospital, Suzhou, Jiangsu Province, China.
authors: Chuanlu
authors: C
authors: Ren
authors: Department of Haematology, PLA 100th Hospital, Suzhou, Jiangsu Province, China.
authors: Haifei
authors: H
authors: Chen
authors: Innovation Centre of Haematology and the Key Laboratory of Thrombosis and Haemostasis of the Ministry of Health, Jiangsu Institute of Haematology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
authors: Ziqiang
authors: Z
authors: Yu
authors: Department of Neurology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, China.
authors: Wanli
authors: W
authors: Don
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use*; D002220:Carbamazepine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002648:Child; D005260:Female; D006470:Hemorrhage / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D000078330:Oxcarbazepine; D012640:Seizures / Q000150:complications / Q000188:drug therapy*; D013546:Sweating
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine; D000078330:Oxcarbazepine
keywords: Haematidrosis; bleeding; epilepsy; oxcarbazepine