title: The role of positron emission tomography/computed tomography in planning radiotherapy in endometrial cancer.
abstract: OBJECTIVE
  The optimal method of assessing disease distribution in endometrial cancer is widely debated. Knowledge of disease distribution assists in planning adjuvant radiotherapy; in this study we used positron emission tomography/computed tomography (PET/CT) to assess disease distribution before radiotherapy.
  
  
  METHODS
  Seventy-three consecutive patients referred to the Peter MacCallum Cancer Centre for adjuvant radiotherapy for endometrial cancer, with either high-risk disease after a hysterectomy or recurrent disease, had a PET/CT before treatment. The findings on PET/CT and clinical course were recorded.
  
  
  RESULTS
  PET/CT found additional disease in 35% of postoperative patients, changing planned treatment in 31%. In the group with known recurrence, additional disease was found in 72%, changing management in 36%.
  
  
  CONCLUSIONS
  PET/CT is a valuable tool for planning radiotherapy in endometrial cancer.
authors: *Peter MacCallum Cancer Centre, Melbourne, Australia; and †Biostatistics and Computational Biology, Population Health, University of Otago, Christchurch, New Zealand.
authors: Bryony
authors: B
authors: Simcock
authors: Kailash
authors: K
authors: Narayan
authors: Elizabeth
authors: E
authors: Drummond
authors: David
authors: D
authors: Bernshaw
authors: Elizabeth
authors: E
authors: Wells
authors: Rodney J
authors: RJ
authors: Hicks
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging* / Q000401:mortality / Q000532:radiotherapy; D005260:Female; D019788:Fluorodeoxyglucose F18; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods; D060787:Neoplasm Grading; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000401:mortality / Q000532:radiotherapy; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography / Q000379:methods*; D011379:Prognosis; D019275:Radiopharmaceuticals; D011880:Radiotherapy Planning, Computer-Assisted; D018714:Radiotherapy, Adjuvant; D015996:Survival Rate; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18