title: [Preoperative screening of deep venous thrombosis: cutoff value of D-dimer, age and BMI for further examination of DVT by echo-color-Doppler].
abstract: BACKGROUND
  Pulmonary embolism (PE) is morbid perioperative complication and deep vein thrombosis (DVT) is the most common cause of PE. Echo-color-Doppler examination for DVT is a specific test. But it would not be cost-effective to perform in all preoperative patients. The aim of this study was to determine the cut-off value of age body mass index (BMI) and D-dimer (DD) for further examination (echo) of DVT.
  
  
  METHODS
  The age, BMI and DD of patients who had undergone echo-color-Doppler test were retrospectively examined. There were 94 patients scheduled for elective operation under general anesthesia from May 2004 to March 2005 in Himeji Red Cross Hospital.
  
  
  RESULTS
  Forty five patients were with DVT and 49 patients were without DVT. There was no significant difference between the two groups in BMI. The cut-off value of age was 39 years and that of D-dimer was 0.8 μg x ml(-1). Discriminant function of DVT and D-dimer age were obtained in the formulae, Z = 0.0047 x (Age)(2) - 0.0565 x (D-D)(2) - 0.0046 (Age) x (DD) - 0.7085 x (Age) +0.546 x (DD) + 26.5674.
  
  
  CONCLUSIONS
  We recommend that the patients above the discriminant function curve of DVT should undergo further examination for DVT.
authors: Mutsuko
authors: M
authors: Matsumoto
authors: Toshiaki
authors: T
authors: Kurasako
authors: Takae
authors: T
authors: Niguma
authors: Yutaka
authors: Y
authors: Yaida
authors: Etsu
authors: E
authors: Iwasaki
authors: Noriko
authors: N
authors: Ishii
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D015992:Body Mass Index; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D057234:Preoperative Period; D011655:Pulmonary Embolism / Q000209:etiology / Q000517:prevention & control; D012189:Retrospective Studies; D018615:Ultrasonography, Doppler, Color; D020246:Venous Thrombosis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging
chemical_list: D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D