title: A new mode for highly sensitive and specific detection of DNA based on exonuclease III-assisted target recycling amplification and mismatched catalytic hairpin assembly.
abstract: A novel electrochemical sensing strategy was developed for highly sensitive and specific detection of DNA by combining the exonuclease III-assisted target recycling amplification with mismatched catalytic hairpin assembly. The proposed method showed high sensitivity and selectivity with a dynamic response range from 100 fM to 5 nM.
authors: Key Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing 400016, P. R. China. dingshijia@163.com.
authors: Chenyang
authors: C
authors: Tao
authors: Yurong
authors: Y
authors: Yan
authors: Hua
authors: H
authors: Xiang
authors: Dan
authors: D
authors: Zhu
authors: Wei
authors: W
authors: Cheng
authors: Huangxian
authors: H
authors: Ju
authors: Shijia
authors: S
authors: Ding
mesh_terms: D015374:Biosensing Techniques; D002384:Catalysis; D004247:DNA / Q000032:analysis*; D055664:Electrochemical Techniques; D005090:Exodeoxyribonucleases / Q000737:chemistry*; D021141:Nucleic Acid Amplification Techniques
chemical_list: D004247:DNA; D005090:Exodeoxyribonucleases; C020133:exodeoxyribonuclease III