title: Hydroxysulfenylation of electron-deficient alkenes through an aerobic copper catalysis.
abstract: A copper-catalyzed hydroxysulfenylation of α,β-unsaturated esters/amides is reported. The method presents a selective and efficient synthesis of β-hydroxysulfides bearing electron-withdrawing groups. The synthetic utility of this method is demonstrated by the concise synthesis of the anticancer drug bicalutamide.
authors: Department of Chemistry, Renmin University of China , Beijing 100872, China.
authors: Hui
authors: H
authors: Xi
authors: Bicheng
authors: B
authors: Deng
authors: Zhenzhen
authors: Z
authors: Zong
authors: Shenglin
authors: S
authors: Lu
authors: Zhiping
authors: Z
authors: Li