title: The early antibiotic therapy in septic patients--milestone or sticking point?
abstract: Sepsis is one of the oldest and most elusive syndromes in medicine. Every effort should be made to treat these patients with the best available evidence. As a milestone, empiric antimicrobial therapy is essential in order to reduce morbidity and mortality of septic patients. As a sticking point, the use of broad-spectrum antimicrobial agents may be associated with induction of resistance among common pathogens.
authors: Michael
authors: M
authors: Bernhard
authors: Christoph
authors: C
authors: Lichtenstern
authors: Christian
authors: C
authors: Eckmann
authors: Markus A
authors: MA
authors: Weigand
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D024881:Drug Resistance, Bacterial; D006801:Humans; D018805:Sepsis / Q000188:drug therapy*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents