title: Persistent organic pollutants in a marine bivalve on the Marennes-Oléron Bay and the Gironde Estuary (French Atlantic Coast) - part 2: potential biological effects.
abstract: Contaminant effects on defence responses of ecologically and economically important organisms, such as the Pacific oyster Crassostrea gigas, are likely to influence their ability to resist infectious diseases, particularly at the young stages. The aim of this study was to explore the potential relationships between organic contaminants accumulated in the soft tissues of juvenile oysters, defence responses and physiological condition. Oysters were transplanted during summer and winter periods in different sites in the Marennes-Oléron Bay, the first area of oyster production in France, and in the Gironde Estuary, the biggest estuary in Occidental Europe. Amongst the battery of biochemical and physiological biomarkers applied in the present work [superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx), malondyaldehyde (MDA), catecholase, laccase and lysozyme in gills, digestive glands, mantle and haemolymph, glycogen, proteins and lipids in the digestive gland and the condition index at the whole-organism level], MDA and lysozyme in the digestive gland and SOD, GPx and laccase in plasma contributed in order to significantly discriminate the sites in which oysters bioaccumulated different levels of heavy polycyclic aromatic hydrocarbons (HPAHs), polychlorobiphenyls (PCBs), polybromodiphenylethers (PBDEs), dichlorodiphenyltrichloroethanes (DDTs) and lindane. These results strengthen the hypothesis that it is possible to differentiate sites depending on their contamination levels and biological effects by carrying out studies with transplanted juvenile oysters. In addition, correlations were found between antioxidant and immune-defence responses, and PAH and DDT body burdens in the first area of oyster production in France (the Marennes-Oléron Bay) and where considerable oyster mortalities have been reported. This result suggests that the presence of organic chemical contaminants in the Marennes-Oléron Bay may influence defence responses in juveniles of C. gigas, and, therefore, could influence their ability to resist infectious diseases.
authors: Littoral Environnement and Sociétés (LIENSs), UMR 7266 CNRS, Université de La Rochelle, 2 rue Olympe de Gouges, F-17042, the Rochelle Cedex 01, France. Electronic address: aluna1508@yahoo.com.
authors: A
authors: A
authors: Luna-Acosta
authors: Littoral Environnement and Sociétés (LIENSs), UMR 7266 CNRS, Université de La Rochelle, 2 rue Olympe de Gouges, F-17042, the Rochelle Cedex 01, France.
authors: P
authors: P
authors: Bustamante
authors: Université Bordeaux 1, Laboratoire de Physico-ToxicoChimie de l'environnement (LPTC), UMR EPOC (UMR5805 CNRS-Université de Bordeaux 1), 351 Cours de the Libération, 33405 Talence, France; CNRS, Laboratoire de Physico-ToxicoChimie de l'environnement (LPTC), EPOC (UMR 5805, CNRS-Université de Bordeaux 1), 351 Cours de the Libération, 33405 Talence, France.
authors: H
authors: H
authors: Budzinski
authors: Littoral Environnement and Sociétés (LIENSs), UMR 7266 CNRS, Université de La Rochelle, 2 rue Olympe de Gouges, F-17042, the Rochelle Cedex 01, France.
authors: V
authors: V
authors: Huet
authors: Littoral Environnement and Sociétés (LIENSs), UMR 7266 CNRS, Université de La Rochelle, 2 rue Olympe de Gouges, F-17042, the Rochelle Cedex 01, France.
authors: H
authors: H
authors: Thomas-Guyon
mesh_terms: D000818:Animals; D061006:Bays; D002374:Catalase / Q000378:metabolism; D049896:Crassostrea / Q000378:metabolism*; D004784:Environmental Monitoring; D063366:Estuaries; D005602:France; D005880:Gills / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D015386:Hazardous Substances; D008315:Malondialdehyde / Q000378:metabolism; D009113:Muramidase / Q000378:metabolism; D011078:Polychlorinated Biphenyls; D011084:Polycyclic Aromatic Hydrocarbons / Q000378:metabolism; D012623:Seawater; D014874:Water Pollutants, Chemical / Q000378:metabolism*
chemical_list: D015386:Hazardous Substances; D011084:Polycyclic Aromatic Hydrocarbons; D014874:Water Pollutants, Chemical; D008315:Malondialdehyde; D011078:Polychlorinated Biphenyls; D002374:Catalase; D005979:Glutathione Peroxidase; D009113:Muramidase
keywords: Active biomonitoring; Crassostrea gigas; Immune humoral defences; Oxidative stress; Persistent organic pollutants; Polycyclic aromatic hydrocarbons