title: The contact length between the tumor contour and the lung on computed tomography is a risk factor for pleural recurrence after complete resection of thymoma.
abstract: OBJECTIVE
  Among the perioperative findings which included patient characteristics and imaging, surgical, and pathological findings of the tumor, the risk factors for pleural recurrence (PR) after complete resection of thymoma were explored.
  
  
  METHODS
  Fifty-three patients with Masaoka stage I to III thymoma who underwent complete resection, and five patients with stage IVa disease accompanied with pleural dissemination were analyzed. In these cohorts, the patients were divided into a non-recurrence (NR) group, PR group and stage IVa group. The maximum tumor diameter (TD) and the contact length between the tumor contour and the lung (CLTL) were measured at the maximum section of the tumor on axial computed tomography. A multivariate analysis including gender, age, TD, CLTL, tumor adhesion to the lung, Masaoka stage, and WHO histological type was performed to estimate risk factors for PR.
  
  
  RESULTS
  The median follow-up period was 76.9 months. PR developed in six patients. The mean TDs were 44 mm in the NR group, 62 mm in the PR group and 73 mm in the stage IVa group, respectively. The mean CLTLs were 47, 90 and 96 mm, respectively. The CLTLs of the PR group were significantly longer than those of the NR group (p < 0.001), although the TDs were not significantly different between the two groups. The multivariate analysis indicated that CLTL was only a risk factor for PR (p = 0.046).
  
  
  CONCLUSIONS
  The CLTL was significantly associated with the PR after complete resection of thymoma.
authors: Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
authors: Taketo
authors: T
authors: Kato
authors: Shingo
authors: S
authors: Iwano
authors: Tetsuo
authors: T
authors: Taniguchi
authors: Koji
authors: K
authors: Kawaguchi
authors: Takayuki
authors: T
authors: Fukui
authors: Futoshi
authors: F
authors: Ishiguro
authors: Koichi
authors: K
authors: Fukumoto
authors: Shota
authors: S
authors: Nakamura
authors: Akihiro
authors: A
authors: Hirakawa
authors: Kohei
authors: K
authors: Yokoi
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009367:Neoplasm Staging; D012189:Retrospective Studies; D012307:Risk Factors; D013945:Thymoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013953:Thymus Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D047368:Tumor Burden