title: Drug discovery. Tying up a transcription factor.
authors: Department of Biological Engineering, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
authors: Andrew
authors: A
authors: Chen
authors: Department of Biological Engineering, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA. Broad Institute of MIT and Harvard, Cambridge, MA, USA. koehler@mit.edu.
authors: Angela N
authors: AN
authors: Koehler
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D015514:Oncogene Proteins, Fusion / Q000037:antagonists & inhibitors*
chemical_list: C000595793:2,2'-(5,5'-((oxybis(ethane-2,1-diyl))bis(oxy))bis(pyridine-5,2-diyl))bis(6-(trifluoromethoxy)-1H-benzo(d)imidazole); D000970:Antineoplastic Agents; D001562:Benzimidazoles; C095514:CBFbeta-MYH11 fusion protein; D015514:Oncogene Proteins, Fusion