title: ZnO nanocomposites modified by hydrophobic and hydrophilic silanes with dramatically enhanced tunable fluorescence and aqueous ultrastability toward biological imaging applications.
abstract: Multicolor ZnO quantum dots (QDs) were synthesized and further modified with hydrophobic hexadecyltrimethoxysilane (HDS) and then hydrophilic aminopropyltriethoxysilane (APS) bilayers, resulting in amine-functionalized ZnO@HDS@APS nanocomposites with tunable fluorescence from blue to green yellow. Systematic investigations verify that the resulting ZnO@HDS@APS could display extremely high stability in aqueous media and unexpectedly, dramatically-enhanced fluorescence intensities, which are about 10-fold higher than those of bare ZnO QDs. The feasibility of the as-prepared ZnO nanocomposites for blood, cell, and tissue imaging was preliminarily demonstrated, promising the wide bio-applications for cell or tissue imaging, proteome analysis, drug delivery, and molecular labeling.
authors: Shandong Province Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China.
authors: Shuying
authors: S
authors: Li
authors: Shandong Province Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China.
authors: Zongzhao
authors: Z
authors: Sun
authors: Shandong Province Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China.
authors: Rui
authors: R
authors: Li
authors: Shandong Province Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China.
authors: Minmin
authors: M
authors: Dong
authors: Shandong Province Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China.
authors: Liyan
authors: L
authors: Zhang
authors: Shandong Province Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China.
authors: Wei
authors: W
authors: Qi
authors: College of Sport Science, Qufu Normal University, Qufu 273165, P. R. China.
authors: Xuelin
authors: X
authors: Zhang
authors: Shandong Province Key Laboratory of Life-Organic Analysis, College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China.
authors: Hua
authors: H
authors: Wang
mesh_terms: D000818:Animals; D057927:Hydrophobic and Hydrophilic Interactions; D051379:Mice; D008856:Microscopy, Fluorescence; D009132:Muscles / Q000737:chemistry / Q000166:cytology / Q000378:metabolism; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D011437:Propylamines / Q000737:chemistry*; D045663:Quantum Dots / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000737:chemistry / Q000378:metabolism; D012821:Silanes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D014466:Ultraviolet Rays; D015034:Zinc Oxide / Q000737:chemistry*
chemical_list: D011437:Propylamines; D012821:Silanes; C477625:amino-propyl-triethoxysilane; D015034:Zinc Oxide