title: A decade after International Subarachnoid Aneurysm Trial: Coiling as a first choice treatment in the management of intracranial aneurysms - Technical feasibility and early management outcomes.
abstract: OBJECTIVE
  The technique of coiling has evolved in the last decade with evolution in both equipment and material. The preferable treatment of intracranial aneurysms at our center is endovascular coiling. We discuss the technical and management outcomes of consecutive patients treated with this approach and compare our results with a decade old International Subarachnoid Aneurysm Trial.
  
  
  METHODS
  Between January 2006 and November 2011, a total of 324 aneurysms in 304 consecutive patients were treated. Endovascular treatment was done in 308 aneurysms (95.0%) in 288 patients while 16 patients (5%) underwent surgical clipping. Of the 308 aneurysms treated endovascularly, 269 (87.3%) were ruptured, and 39 (12.7%) were unruptured aneurysms.
  
  
  RESULTS
  The endovascular coiling was feasible in all (99.6%) but 1 case. The immediate postoperative occlusion status was complete occlusion in 240 aneurysms (77.9%), neck remnant in 57 aneurysms (18.5%), and aneurysm remnant in 11 aneurysms (3.6%). Technical issues - with or without clinical effect-were encountered in 20 patients (6.9%). They included 18 thromboembolic events (6.2%) and intraprocedural aneurysmal rupture in 2 cases (0.7%). In "good grade" patients, H and H grade 1-3, a good outcome (modified Rankin score [mRS] 0-2) was in 87.6% patients while the bad outcome (mRS 3-5) was in 10.2% patients and mortality of 2.2%. In "bad grade" patients, H and H grade 3-5, a good outcome was in 29.2%, and bad outcome was in 41.7% patients with mortality was 29.1%. In the unruptured aneurysm group, the good outcome was seen in 97.7% and bad outcome in 2.3% with no mortality.
  
  
  CONCLUSIONS
  In the current era, the favorable results of coiling demonstrated in previous studies may be applicable to the larger proportion of patients. In our series of consecutively treated patients using latest advances, such as three-dimensional imaging and the interventional material, endovascular management as first choice was feasible in 95% of patients with good technical and management outcomes.
authors: Department of Neurointervention surgery and Neurosurgery, Institute of Neurosciences, Medanta Hospital, Gurgaon, Haryana, India.
authors: Gaurav
authors: G
authors: Goel
authors: Department of Neurointervention surgery and Neurosurgery, Institute of Neurosciences, Medanta Hospital, Gurgaon, Haryana, India.
authors: Vipul
authors: V
authors: Gupta
authors: Department of Neurointervention surgery and Neurosurgery, Institute of Neurosciences, Medanta Hospital, Gurgaon, Haryana, India.
authors: Swati
authors: S
authors: Chinchure
authors: Department of Neurointervention surgery and Neurosurgery, Institute of Neurosciences, Medanta Hospital, Gurgaon, Haryana, India.
authors: Aditya
authors: A
authors: Gupta
authors: Department of Neurointervention surgery and Neurosurgery, Institute of Neurosciences, Medanta Hospital, Gurgaon, Haryana, India.
authors: Gurmeen
authors: G
authors: Kaur
authors: Department of Neurointervention surgery and Neurosurgery, Institute of Neurosciences, Medanta Hospital, Gurgaon, Haryana, India.
authors: Ajaya N
authors: AN
authors: Jha
keywords: Aneurysm; coiling; management; subarachnoid hemorrhage