title: Cost-effective treatment modalities for reducing morbidity associated with chronic kidney disease.
abstract: Chronic kidney disease (CKD) is a worldwide health problem with increasing prevalence and incidence. Guidelines suggest that early referral to a nephrologist to manage advanced stage (4+) patients with CKD is an effective treatment strategy, with earlier stage patients best managed through primary care physicians. Should patients with CKD progress to total kidney failure, several therapies are available that vary widely in costs. Kidney transplantation offers the lowest costs and highest quality of life, followed in ascending order of costs by peritoneal dialysis, home hemodialysis and facility-based hemodialysis. Earlier detection of CKD may prevent progression to kidney failure, and accurate risk prediction of end-stage kidney failure may improve clinical planning, outcomes and resource allocation.
authors: Seven Oaks General Hospital Renal Program, 2300 McPhillips Street, 2PD12 Winnipeg, MB R2V 3M3, Canada.
authors: Thomas W
authors: TW
authors: Ferguson
authors: Navdeep
authors: N
authors: Tangri
authors: Claudio
authors: C
authors: Rigatto
authors: Paul
authors: P
authors: Komenda
mesh_terms: D003362:Cost-Benefit Analysis; D018450:Disease Progression; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000191:economics / Q000503:physiopathology / Q000628:therapy*; D016030:Kidney Transplantation / Q000191:economics / Q000379:methods; D015995:Prevalence; D011788:Quality of Life; D012017:Referral and Consultation; D006435:Renal Dialysis / Q000191:economics / Q000379:methods*; D051436:Renal Insufficiency, Chronic / Q000191:economics / Q000503:physiopathology / Q000628:therapy*
keywords: chronic kidney disease; cost–effectiveness; dialysis; economic analysis; hemodialysis; home hemodialysis; peritoneal dialysis; screening; transplantation; treatment modalities