title: Efficacy of a novel skin antiseptic against carbapenem-resistant Enterobacteriaceae.
abstract: Infections caused by carbapenem-resistant Enterobacteriaceae (CRE) are increasing on a global scale. Because of the need for CRE transmission prevention and control, we sought to evaluate the efficacy of a silver-based skin antiseptic against these organisms. Using a human skin analog, a third party laboratory conducted efficacy testing. The results suggest that this product provides antimicrobial activity against CRE on human skin. Because of the unique properties, this antiseptic may be useful for daily bathing of hospitalized patients to assist in the control of CRE.
authors: University of Louisville School of Medicine, Department of Medicine, Division of Infectious Diseases, Clinical and Translational Research Support Unit, Healthcare Epidemiology Program, Louisville, KY. Electronic address: tim.wiemken@louisville.edu.
authors: Timothy L
authors: TL
authors: Wiemken
authors: University of Louisville School of Medicine, Department of Medicine, Division of Infectious Diseases, Clinical and Translational Research Support Unit, Healthcare Epidemiology Program, Louisville, KY.
authors: Robert R
authors: RR
authors: Kelley
authors: University of Louisville School of Medicine, Department of Medicine, Division of Infectious Diseases, Clinical and Translational Research Support Unit, Healthcare Epidemiology Program, Louisville, KY.
authors: Ruth M
authors: RM
authors: Carrico
authors: University of Louisville School of Medicine, Department of Medicine, Division of Infectious Diseases, Clinical and Translational Research Support Unit, Healthcare Epidemiology Program, Louisville, KY.
authors: Laura E
authors: LE
authors: Binford
authors: University of Louisville School of Medicine, Department of Medicine, Division of Infectious Diseases, Clinical and Translational Research Support Unit, Healthcare Epidemiology Program, Louisville, KY.
authors: Brian E
authors: BE
authors: Guinn
authors: University of Louisville School of Medicine, Department of Medicine, Division of Infectious Diseases, Clinical and Translational Research Support Unit, Healthcare Epidemiology Program, Louisville, KY.
authors: William A
authors: WA
authors: Mattingly
authors: University of Louisville School of Medicine, Department of Medicine, Division of Infectious Diseases, Clinical and Translational Research Support Unit, Healthcare Epidemiology Program, Louisville, KY.
authors: Paula
authors: P
authors: Peyrani
authors: University of Louisville School of Medicine, Department of Medicine, Division of Infectious Diseases, Clinical and Translational Research Support Unit, Healthcare Epidemiology Program, Louisville, KY.
authors: Julio A
authors: JA
authors: Ramirez
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D015780:Carbapenems / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D004756:Enterobacteriaceae Infections / Q000188:drug therapy*; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects; D012834:Silver / Q000627:therapeutic use*; D012867:Skin / Q000382:microbiology*
chemical_list: D000891:Anti-Infective Agents, Local; D015780:Carbapenems; C586932:colloidal silver; D012834:Silver
keywords: Carbapenemase; Colloidal silver; Daily bathing; Skin antisepsis