title: [Algorithm of treatment postthrombotic disease of the lower extremities].
abstract: The results of application of pathogenetically substantiated diagnostic algorithm for determination of the treatment method in patients, suffering postthrombotic disease of the lower extremities, are adduced. Using algorithm proposed a clinical state was estimated, subfascial pressure on the shin was determined, ultrasound duplex scanning (USDS) of venous system was conducted, the stimulation electroneuromyography of the shins done, and a level of D-dimer (DD) with activity of antithrombin-III (AT--III) in general and regional blood flow with calculation of its ratio were established. In 33 (31.1%) patients a conservative therapy was conducted, in 34 (32.1%)--a postponed surgical intervention, in 39 (36.8%)--surgical correction of the venous blood flow, in 22 (20.8%)--preparation and closure of trophic ulcers in accordance to the clinic method. Determination of the DD level and the AT-III activity together with data of USDS have permitted to establish differentially the indications for performance of a vein-correcting operative interventions.
authors: D L
authors: DL
authors: Buzmakov
mesh_terms: D000328:Adult; D000990:Antithrombin III / Q000378:metabolism; D019468:Disease Management; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D054070:Postthrombotic Syndrome / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D018616:Ultrasonography, Doppler, Duplex; D014647:Varicose Ulcer / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D014648:Varicose Veins / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D014680:Veins / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D020246:Venous Thrombosis / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D000990:Antithrombin III