title: Cost-utility of a lifestyle intervention in adolescents and young adults with spastic cerebral palsy.
abstract: OBJECTIVE
  To evaluate the cost-utility of a lifestyle intervention among adolescents and young adults with cerebral palsy.
  
  
  METHODS
  Single-blind, randomized controlled trial.
  
  
  METHODS
  Six university hospital/clinics in the Netherlands.
  
  
  METHODS
  Fifty-seven adolescents and young adults with spastic cerebral palsy classified as Gross Motor Functioning Classification System (GMFCS) level I-IV.
  
  
  METHODS
  A 6-month lifestyle intervention consisting of physical fitness training combined with counselling sessions focusing on physical behaviour and sports participation.
  
  
  METHODS
  Data on quality of life, direct medical costs and productivity costs were collected using standardized questionnaires. Quality adjusted life years (QALYs) were derived from the Short-Form 36 questionnaire using the Short-Form 6D.
  
  
  RESULTS
  Quality of life remained stable over time for both groups. No significant differences between groups were found for direct medical costs or productivity costs. A cost-utility ratio of -€23,664 per QALY was found for the lifestyle intervention compared with no treatment.
  
  
  CONCLUSIONS
  The results of this study are exploratory, but indicate that implementing a lifestyle intervention for the cerebral palsy population might be cost-effective or cost-saving compared with offering no intervention to improve physical behaviour and fitness. However, the large range of uncertainty for the cost-utility ratio should be taken into account and the results interpreted with caution.
authors: Rehabilitation Medicine, ErasmusMC, Rotterdam, The Netherlands . j.slaman@erasmusmc.nl.
authors: Jorrit
authors: J
authors: Slaman
authors: Rita
authors: R
authors: van den Berg-Emons
authors: Siok Swan
authors: SS
authors: Tan
authors: Heleen
authors: H
authors: Russchen
authors: Jetty
authors: J
authors: van Meeteren
authors: Henk
authors: H
authors: Stam
authors: Marij
authors: M
authors: Roebroeck
mesh_terms: D000293:Adolescent; D000328:Adult; D002547:Cerebral Palsy / Q000191:economics* / Q000628:therapy; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D017063:Outcome Assessment, Health Care; D010809:Physical Fitness / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology*; D016037:Single-Blind Method; D055815:Young Adult