title: New group 6 metal carbonyl complexes with 4,5-dimethyl-N,N-bis(pyridine-2-yl-methylene)benzene-1,2-diimine Schiff base: synthesis, spectral, cyclic voltammetry and biological activity studies.
abstract: Thermal reaction of M(CO)6 (M=Cr, Mo or W) with a Schiff base (DMPA) derived from the condensation of 4,5-dimethyl-1,2-phenylenediamine and pyridine-2-carboxaldehyde in THF in absence and presence of a secondary ligand; 2-aminobenzimidazole (Abz), thiourea (Tu) or 2-(2'-pyridyl)benzimidazole (pybz) were studied. The reaction of Cr(CO)6 gave the four complexes Cr2(CO)2(DMPA)2; 1, Cr(DMPA)2(Abz)2; 2, Cr2(CO)4(DMPA)2(Tu)2; 3 and Cr(DMPA)2(Pybz); 4, while the thermal reaction of Mo(CO)6 resulted in the formation of the two complexes Mo2(O)6(DMPA)2; 5, and Mo2(O)2(CO)2(DMPA)2(Tu)2; 6. Thermal reaction of W(CO)6 and the Schiff base DMPA gave the complex W(O)2(DMPA)2; 7. The ligand DMPA and its metal complexes have been reported and characterized based on elemental analyses, IR, (1)H NMR, magnetic measurements, and thermal analysis. Cyclic voltammetry and biological activity were also investigated.
authors: Chemistry Department, Faculty of Science, Fayoum University, Fayoum, Egypt.
authors: Rania G
authors: RG
authors: Mohamed
authors: Chemistry Department, Faculty of Science, Fayoum University, Fayoum, Egypt.
authors: Fatma M
authors: FM
authors: Elantabli
authors: Chemistry Department, Faculty of Science, Fayoum University, Fayoum, Egypt.
authors: Nadia H
authors: NH
authors: Helal
authors: Chemistry Department, Faculty of Science, Fayoum University, Fayoum, Egypt. Electronic address: samirmedani@yahoo.com.
authors: Samir M
authors: SM
authors: El-Medani
mesh_terms: D001230:Aspergillus / Q000187:drug effects; D001554:Benzene / Q000138:chemical synthesis* / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects; D055664:Electrochemical Techniques; D008024:Ligands; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000494:pharmacology*; D010655:Phenylenediamines / Q000138:chemical synthesis* / Q000494:pharmacology*; D066244:Proton Magnetic Resonance Spectroscopy; D012545:Schiff Bases / Q000138:chemical synthesis* / Q000494:pharmacology*; D013055:Spectrophotometry, Infrared; D013211:Staphylococcus aureus / Q000187:drug effects; D013818:Thermogravimetry
chemical_list: D008024:Ligands; D009942:Organometallic Compounds; D010655:Phenylenediamines; D012545:Schiff Bases; D001554:Benzene
keywords: Biological activity; Cyclic voltammetry; Metal carbonyls; Spectral and thermal studies