title: Renal denervation: current status and future applications.
abstract: Despite the variety of antihypertensive agents that are available, resistant hypertension remains a significant clinical problem and a substantial economic burden. Over the past several years, renal sympathetic denervation has been introduced as a potential therapeutic option for this clinical problem. It is a catheter-based procedure that is showing promising results and appears to be associated with minimal or low risk. Thus far, two completed clinical trials have demonstrated excellent safety and encouraging outcomes. A review of these trials is the focus of this article, in addition to the analysis of ongoing studies, and the possible future applications of this technique.
authors: Sabas I
authors: SI
authors: Gomez
authors: Pablo
authors: P
authors: Urbandt
authors: Nirat
authors: N
authors: Beohar
authors: Division of Internal Medicine and Columbia University Division of Cardiology, Mount Sinai Heart Institute, Miami Beach, FL.
authors: Orlando
authors: O
authors: Santana
mesh_terms: D000818:Animals; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects; D017115:Catheter Ablation / Q000009:adverse effects; D004351:Drug Resistance; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D007668:Kidney / Q000294:innervation*; D013562:Sympathectomy / Q000009:adverse effects / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents