title: Surface charge regulation of osteogenic differentiation of mesenchymal stem cell on polarized ferroelectric crystal substrate.
abstract: Polarized ferroelectric crystal lithium niobate wafers with different cuts are selected to offer differently charged surfaces. By induction of the mesenchymal stem cells differentiation into osteoblasts on different charged surfaces, the specific osteogenic-associated markers are assessed and the results illustrate that the positively charged wafer surface enhances rBMMSCs osteogenic differentiation.
authors: Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 100083, China.|State Key Lab of Crystal Materials, Shandong University, 27 Shandanan Road, Jinan, 250100, China.
authors: Jianhua
authors: J
authors: Li
authors: Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 100083, China.
authors: Xiaoning
authors: X
authors: Mou
authors: State Key Lab of Crystal Materials, Shandong University, 27 Shandanan Road, Jinan, 250100, China.
authors: Jichuan
authors: J
authors: Qiu
authors: Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 100083, China.
authors: Shu
authors: S
authors: Wang
authors: State Key Lab of Crystal Materials, Shandong University, 27 Shandanan Road, Jinan, 250100, China.
authors: Dongzhou
authors: D
authors: Wang
authors: State Key Lab of Crystal Materials, Shandong University, 27 Shandanan Road, Jinan, 250100, China.
authors: Dehui
authors: D
authors: Sun
authors: Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 100083, China.
authors: Weibo
authors: W
authors: Guo
authors: Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 100083, China.
authors: Deshuai
authors: D
authors: Li
authors: Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 100083, China.
authors: Anil
authors: A
authors: Kumar
authors: Biomaterials and Tissue Engineering Group, School of Dentistry, University of Leeds, Leeds, LS2 9LU, UK.
authors: Xuebin
authors: X
authors: Yang
authors: Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 100083, China.
authors: Aixue
authors: A
authors: Li
authors: Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 100083, China.|State Key Lab of Crystal Materials, Shandong University, 27 Shandanan Road, Jinan, 250100, China.
authors: Hong
authors: H
authors: Liu
mesh_terms: D002454:Cell Differentiation / Q000187:drug effects / Q000502:physiology*; D002478:Cells, Cultured; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000187:drug effects / Q000502:physiology*; D009556:Niobium / Q000494:pharmacology; D010006:Osteoblasts / Q000187:drug effects / Q000502:physiology*; D010012:Osteogenesis / Q000187:drug effects / Q000502:physiology*; D010087:Oxides / Q000494:pharmacology
chemical_list: D010087:Oxides; D009556:Niobium; C091692:lithium niobate
keywords: mesenchymal stem cells; osteogenic differentiation; polarized ferroelectric crystals; surface charge