title: Non-coding RNAs in gastric cancer.
abstract: Non-coding RNAs (ncRNAs) have recently become increasingly important in the study of cellular metabolism and regulation such as development, proliferation, differentiation and apoptosis. However, the functions of most ncRNAs have remained largely unknown. Recently, studies have begun to characterize the aberrant regulation of ncRNAs in gastric cancer (GC) cells and tissues. These ncRNAs have a close relationship with drug resistance, and with the occurrence, development, invasion and metastasis of tumors, so they could possibly become new therapeutic targets and treatment tools for GC in the future. The present review summarized current advances in our knowledge of the roles of ncRNAs in GC.
authors: Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, 155 North Nanjing Street, Heping District, Shenyang City 110001, China. Electronic address: cmuoscar@163.com.
authors: Jun
authors: J
authors: Wang
authors: Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, 155 North Nanjing Street, Heping District, Shenyang City 110001, China. Electronic address: songyongxi840309@126.com.
authors: Yong-Xi
authors: YX
authors: Song
authors: Department of Surgical Oncology and General Surgery, First Hospital of China Medical University, 155 North Nanjing Street, Heping District, Shenyang City 110001, China. Electronic address: josieon826@sina.cn.
authors: Zhen-Ning
authors: ZN
authors: Wang
mesh_terms: D000818:Animals; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D062085:RNA, Long Noncoding / Q000502:physiology; D020537:RNA, Small Nucleolar / Q000502:physiology; D058727:RNA, Small Untranslated / Q000502:physiology; D022661:RNA, Untranslated / Q000502:physiology*; D013274:Stomach Neoplasms / Q000235:genetics*
chemical_list: C094335:H19 long non-coding RNA; C561566:HOTAIR long untranslated RNA, human; D062085:RNA, Long Noncoding; D020537:RNA, Small Nucleolar; D058727:RNA, Small Untranslated; D022661:RNA, Untranslated
keywords: Gastric cancer; Long non-coding RNA; MicroRNA; Non-coding RNA; Small interfering RNA