title: Real time detection of live microbes using a highly sensitive bioluminescent nitroreductase probe.
abstract: A highly sensitive and selective nitroreductase probe, showing a rapid and strong bioluminescence enhancement (>100-fold in 5 minutes), and its initial application in the real time detection of both Gram positive and Gram negative live bacteria and monitoring of their growth has been reported.
authors: Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China. hoyuay@hku.hk.
authors: Roger H F
authors: RH
authors: Wong
authors: Thomas
authors: T
authors: Kwong
authors: Kwok-Hei
authors: KH
authors: Yau
authors: Ho Yu
authors: HY
authors: Au-Yeung
mesh_terms: D052160:Benzothiazoles / Q000737:chemistry / Q000378:metabolism; D006090:Gram-Negative Bacteria / Q000201:enzymology / Q000254:growth & development*; D006094:Gram-Positive Bacteria / Q000201:enzymology / Q000254:growth & development*; D008156:Luciferases / Q000378:metabolism; D008163:Luminescent Measurements; D015335:Molecular Probes / Q000737:chemistry / Q000378:metabolism*; D009601:Nitroreductases / Q000737:chemistry / Q000378:metabolism*
chemical_list: D052160:Benzothiazoles; D015335:Molecular Probes; D008156:Luciferases; D009601:Nitroreductases; C005465:benzothiazole