title: Indium triflate-catalyzed stereoselective tandem intramolecular conjugate addition of secondary amines to α,β-bisenones.
abstract: We report an indium triflate-catalyzed stereoselective intramolecular tandem conjugate addition of secondary amines to α,β-bisenones to afford a 1,2,3-trisubstituted six-membered ring bearing diketone substituents in good to excellent yields at room temperature. Various kinds of α,β-bisenones and amines were employed to expand the scope of this chemistry. Intramolecular trapping of indium-enolate by the tethered electrophiles resulted in the stereoselective formation of three contiguous stereogenic centers.
authors: Department of Chemistry, Pukyong National University, Busan, 608-737, Republic of Korea. syseo@pknu.ac.kr.
authors: Bodakuntla
authors: B
authors: Thirupathaiah
authors: SungYong
authors: S
authors: Seo