title: Single-component versus multicomponent dietary goals for the metabolic syndrome: a randomized trial.
abstract: BACKGROUND
  Few studies have compared diets to determine whether a program focused on 1 dietary change results in collateral effects on other untargeted healthy diet components.
  
  
  OBJECTIVE
  To evaluate a diet focused on increased fiber consumption versus the multicomponent American Heart Association (AHA) dietary guidelines.
  
  
  METHODS
  Randomized, controlled trial from June 2009 to January 2014. (ClinicalTrials.gov: NCT00911885).
  
  
  METHODS
  Worcester, Massachusetts.
  
  
  METHODS
  240 adults with the metabolic syndrome.
  
  
  METHODS
  Participants engaged in individual and group sessions.
  
  
  METHODS
  Primary outcome was weight change at 12 months.
  
  
  RESULTS
  At 12 months, mean change in weight was -2.1 kg (95% CI, -2.9 to -1.3 kg) in the high-fiber diet group versus -2.7 kg (CI, -3.5 to -2.0 kg) in the AHA diet group. The mean between-group difference was 0.6 kg (CI, -0.5 to 1.7 kg). During the trial, 12 (9.9%) and 15 (12.6%) participants dropped out of the high-fiber and AHA diet groups, respectively (P = 0.55). Eight participants developed diabetes (hemoglobin A1c level ≥6.5%) during the trial: 7 in the high-fiber diet group and 1 in the AHA diet group (P = 0.066).
  
  
  CONCLUSIONS
  Generalizability is unknown. Maintenance of weight loss after cessation of group sessions at 12 months was not assessed. Definitive conclusions cannot be made about dietary equivalence because the study was powered for superiority.
  
  
  CONCLUSIONS
  The more complex AHA diet may result in up to 1.7 kg more weight loss; however, a simplified approach to weight reduction emphasizing only increased fiber intake may be a reasonable alternative for persons with difficulty adhering to more complicated diet regimens.
  
  
  BACKGROUND
  National Heart, Lung, and Blood Institute.
authors: Yunsheng
authors: Y
authors: Ma
authors: Barbara C
authors: BC
authors: Olendzki
authors: Jinsong
authors: J
authors: Wang
authors: Gioia M
authors: GM
authors: Persuitte
authors: Wenjun
authors: W
authors: Li
authors: Hua
authors: H
authors: Fang
authors: Philip A
authors: PA
authors: Merriam
authors: Nicole M
authors: NM
authors: Wedick
authors: Ira S
authors: IS
authors: Ockene
authors: Annie L
authors: AL
authors: Culver
authors: Kristin L
authors: KL
authors: Schneider
authors: Gin-Fei
authors: GF
authors: Olendzki
authors: James
authors: J
authors: Carmody
authors: Tingjian
authors: T
authors: Ge
authors: Zhiying
authors: Z
authors: Zhang
authors: Sherry L
authors: SL
authors: Pagoto
mesh_terms: D000328:Adult; D000368:Aged; D000572:American Heart Association; D001794:Blood Pressure; D003920:Diabetes Mellitus / Q000175:diagnosis; D004038:Diet, Reducing; D004043:Dietary Fiber / Q000008:administration & dosage*; D005260:Female; D017408:Guidelines as Topic; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology; D008875:Middle Aged; D010349:Patient Compliance; D010352:Patient Dropouts; D012680:Sensitivity and Specificity; D014481:United States; D055105:Waist Circumference; D015431:Weight Loss; D055815:Young Adult