title: Renal oligo- and anhydramnios: cause, course and outcome--a single-center study.
abstract: OBJECTIVE
  To evaluate the outcome of patients with renal oligohydramnios and explore the impact of patient variables on outcome and prognosis.
  
  
  METHODS
  A retrospective single-center study was conducted analyzing 104 pregnancies complicated by oligohydramnios of renal origin from 2001 to 2011. Statistical analysis was performed to assess the influence of pre- and postnatal data on pregnancy outcome, morbidity and mortality.
  
  
  RESULTS
  Prenatal renal diagnoses were as follows: hydronephrosis/megaureter: n = 21 (20.2 %), aberrance in renal form or location: n = 7 (6.7 %), cystic renal disease: n = 28 (26.9 %), renal dysplasia: n = 24 (23.1 %), renal agenesis: n = 42 (30.4 %), posterior urethral valves: n = 11 (10.6 %). Hydronephrosis/megaureter and late onset of oligohydramnios were prognostic factors for fetal survival, whereas renal agenesis and associated anomalies had a negative impact on pregnancy outcome. Prenatal interventions did not improve prognosis.
  
  
  CONCLUSIONS
  Pregnancies complicated by renal oligohydramnios still have a poor outcome. Careful weighing of prognostic factors is necessary to decide about further therapeutic measures.
authors: Department of Gynecology and Obstetrics, University of Muenster, Muenster, Germany, judith.spiro@uk-koeln.de.
authors: Judith Eva
authors: JE
authors: Spiro
authors: Martin
authors: M
authors: Konrad
authors: Esther
authors: E
authors: Rieger-Fackeldey
authors: Katja
authors: K
authors: Masjosthusmann
authors: Susanne
authors: S
authors: Amler
authors: Walter
authors: W
authors: Klockenbusch
authors: Ralf
authors: R
authors: Schmitz
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging; D000328:Adult; D000013:Congenital Abnormalities; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000209:etiology*; D007668:Kidney / Q000002:abnormalities; D007674:Kidney Diseases / Q000151:congenital; D007687:Kidney Tubules, Proximal / Q000002:abnormalities; D008297:Male; D016104:Oligohydramnios / Q000209:etiology*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D011296:Prenatal Diagnosis / Q000009:adverse effects / Q000379:methods*; D011379:Prognosis; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal / Q000379:methods*; D014564:Urogenital Abnormalities