title: Non-virological response to a dolutegravir-containing regimen in a patient harbouring a E157Q-mutated virus in the integrase region.
authors: APHP-Hôpital Necker-Enfants malades, Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France IHU Imagine, Paris, France.
authors: F
authors: F
authors: Danion
authors: AP-HP, Groupe Hospitalier Xavier Bichat-Claude Bernard, UF 301 Laboratoire de Pharmaco-Toxicologie, F-75018 Paris, France.
authors: E
authors: E
authors: Belissa
authors: AP-HP, Groupe Hospitalier Xavier Bichat-Claude Bernard, UF 301 Laboratoire de Pharmaco-Toxicologie, F-75018 Paris, France INSERM, IAME, UMR 1137, Université Paris Diderot, Sorbonne Paris Cité, Paris, France.
authors: G
authors: G
authors: Peytavin
authors: Laboratoire de Biologie et Pharmacologie Appliquée, Centre National de la Recherche Scientifique UMR8113, Cachan, France.
authors: E
authors: E
authors: Thierry
authors: APHP-Hôpital Necker-Enfants malades, Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France IHU Imagine, Paris, France.
authors: F
authors: F
authors: Lanternier
authors: APHP-Hôpital Necker-Enfants malades, Service de Néphrologie et Transplantation Adulte, Paris, France Université Paris Descartes, Sorbonne Paris Cité, RTRS Centaure, Labex Transplantex, Paris, France.
authors: A
authors: A
authors: Scemla
authors: APHP-Hôpital Necker-Enfants malades, Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France IHU Imagine, Paris, France.
authors: O
authors: O
authors: Lortholary
authors: Laboratoire de Biologie et Pharmacologie Appliquée, Centre National de la Recherche Scientifique UMR8113, Cachan, France.
authors: O
authors: O
authors: Delelis
authors: APHP-Hôpital Necker-Enfants malades, Service de Virologie, Paris, France Université Paris Descartes, Sorbonne Paris Cité, EA7327 Paris, France.
authors: V
authors: V
authors: Avettand-Fenoel
authors: APHP-Hôpital Necker-Enfants malades, Service de Maladies Infectieuses et Tropicales, Centre d'Infectiologie Necker-Pasteur, Paris, France Université Paris Descartes, Sorbonne Paris Cité, Paris, France IHU Imagine, Paris, France claudine.duvivier@nck.aphp.fr.
authors: C
authors: C
authors: Duvivier
mesh_terms: D019380:Anti-HIV Agents / Q000008:administration & dosage*; D024882:Drug Resistance, Viral; D006678:HIV / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology; D019427:HIV Integrase / Q000235:genetics*; D006575:Heterocyclic Compounds, 3-Ring / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D020125:Mutation, Missense; D010078:Oxazines; D010879:Piperazines; D011728:Pyridones; D000099226:Dolutegravir
chemical_list: D019380:Anti-HIV Agents; D019427:HIV Integrase; D006575:Heterocyclic Compounds, 3-Ring; D010078:Oxazines; D010879:Piperazines; D011728:Pyridones; D000099226:Dolutegravir
keywords: E157Q mutation; HIV treatment; INSTIs; dolutegravir resistance; integrase strand transfer inhibitors