title: Epilepsia Partialis Continua as Presenting Manifestation of AIDS: A Rarity.
abstract: Seizures, most commonly generalized tonic-clonic, are common in known human immune deficiency virus (HIV) sero-positive patients, and they usually have a focal lesion on brain imaging. However, it is very unusual to see a patient with no premorbid illness presenting with epilepsia partialis continua (EPC) and then being detected HIV seropositive with an Acquired Immune Deficiency Syndrome (AIDS)-defining illness. We report the case of a teenaged boy with no past significant history or known high-risk behavior who presented with recurrent focal seizures of 5 days' duration, EPC, and encephalopathy. His electroencephalogram showed periodic lateralized epileptiform discharges (PLEDS), and magnetic resonance imaging (MRI) of the brain showed abnormal signal changes in the right parieto-occipital cortex and thalamus, both as yet unreported in cytomegalovirus (CMV) encephalitis, which was diagnosed by the cerebrospinal fluid (CSF) analysis.
authors: Neurology Department, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
authors: Bhargavi
authors: B
authors: Ramanujam
authors: Neurology Department, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
authors: Deepa
authors: D
authors: Dash
authors: Department of Medicine, B.D. Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India.
authors: Surekha
authors: S
authors: Dabla
authors: Neurology Department, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India manjari.tripathi1@gmail.com.
authors: Manjari
authors: M
authors: Tripathi
authors: Neurology Department, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.
authors: M V Padma
authors: MV
authors: Srivastava
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000293:Adolescent; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology; D004569:Electroencephalography; D017036:Epilepsia Partialis Continua / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography
keywords: CMV encephalitis; HIV; PLEDS; epilepsia partialis continua