title: Surgical option for intestinal gastrointestinal stromal tumors--perioperative and oncological outcomes of laparoscopic surgery.
abstract: OBJECTIVE
  Laparoscopic surgery (LS) is being adopted for gastrointestinal stromal tumors (GISTs) of the stomach. Few studies have examined the outcome of LS for intestinal GISTs. In the present study, we evaluated the outcomes of LS for intestinal GISTs.
  
  
  METHODS
  This study was a prospective-collecting retrospective review of 85 patients with intestinal GISTs who underwent LS or laparotomy in 102 months. The demographic data and oncological outcomes were compared.
  
  
  RESULTS
  The cohort included 85 patients (26 LS and 59 laparotomy patients). The LS group presented earlier oral resumption and a shorter hospital stay. The recurrence rate, recurrence-free and overall survival were comparable. Tumor size greater than 7 cm [risk ratio (RR)=4.148; p=0.022] and mitotic index of greater than 5/50 high-power fields (RR=5.500; p=0.002) were two predictors for tumor recurrence.
  
  
  CONCLUSIONS
  The study demonstrated that LS for intestinal GISTs leads to oncological outcomes comparable to those of laparotomy. Moreover, LS was associated with favorable perioperative recovery and a shorter hospital stay. With strict precautions, LS is a safe and effective procedure for intestinal GISTs.
authors: Department of Traumatology and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, R.O.C.
authors: Chien-Hung
authors: CH
authors: Liao
authors: Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, R.O.C.
authors: Chun-Nan
authors: CN
authors: Yeh
authors: Department of Traumatology and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, R.O.C.
authors: Shang-Yu
authors: SY
authors: Wang
authors: Department of Traumatology and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, R.O.C.
authors: Chih-Yuan
authors: CY
authors: Fu
authors: Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, R.O.C.
authors: Chun-Yi
authors: CY
authors: Tsai
authors: Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, R.O.C.
authors: Yu-Yin
authors: YY
authors: Liu
authors: Department of Traumatology and Emergency Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, R.O.C.
authors: Chi-Tung
authors: CT
authors: Cheng
authors: Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, R.O.C. Gsurgymet@gmail.com.
authors: Ta-Sen
authors: TS
authors: Yeh
mesh_terms: D000368:Aged; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome
keywords: Laparoscopic surgery; gastrointestinal stromal tumor; intestinal GIST; overall survival; recurrence-free survival; small bowel GIST