title: An antibody-graphene oxide nanoribbon conjugate as a surface enhanced laser desorption/ionization probe with high sensitivity and selectivity.
abstract: Graphene oxide nanoribbons (GONRs) were covalently functionalized with an antibody using polyethylene glycol (PEG) as a linker to produce a novel probe for surface enhanced laser desorption/ionization mass spectrometry (SELDI MS). This probe provides a highly sensitive and selective platform for enrichment and MS detection of small molecules in complex media.
authors: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. qianliu@rcees.ac.cn.
authors: Jing
authors: J
authors: Wang
authors: Mengting
authors: M
authors: Cheng
authors: Zhen
authors: Z
authors: Zhang
authors: Liangqia
authors: L
authors: Guo
authors: Qian
authors: Q
authors: Liu
authors: Guibin
authors: G
authors: Jiang
mesh_terms: D000906:Antibodies / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D007834:Lasers; D015335:Molecular Probes / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013499:Surface Properties
chemical_list: D000906:Antibodies; D015335:Molecular Probes; D037742:Nanotubes, Carbon; D010087:Oxides; D011092:Polyethylene Glycols; D006108:Graphite