title: A conversation with Oliver Smithies.
abstract: Professor Oliver Smithies is the Weatherspoon Eminent Distinguished Professor of Pathology and Laboratory Medicine at the University of North Carolina, Chapel Hill. Along with Mario Capecchi and Martin Evans, Oliver was awarded the Nobel Prize in Medicine in Physiology or Medicine in 2007 for his contributions to the development of gene targeting using homologous recombination in embryonic stem cells. This technique has had an immense impact on biomedical research over the past two decades. Professor Smithies has had a long and distinguished career as a researcher and mentor. Here, he provides an entertaining and enlightening discussion of his life in science.
authors: Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina 27599.
authors: Oliver
authors: O
authors: Smithies
authors: Tom
authors: T
authors: Coffman
mesh_terms: D035843:Biomedical Research; D053595:Embryonic Stem Cells; D018390:Gene Targeting / Q000266:history*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008967:Molecular Biology / Q000266:history*; D009613:Nobel Prize; D011995:Recombination, Genetic / Q000235:genetics
keywords: gene targeting; homologous recombination; stem cell