title: Periodontal disease and late-onset aortic prosthetic vascular graft infection.
abstract: Prosthetic vascular graft infection (PVGI) is a rare but significant complication of arterial reconstructive surgery. Although the relative risk is low, the clinical consequences can be catastrophic. Microbiological data on causative bacteria are limited. We present four cases of late-onset PVGI. Using a culture-independent nucleic acid amplification method for analysis of intraoperative samples, the presence of bacteria highly suggestive of an oral source was reported. Examination by an oral health specialist confirmed the presence of chronic periodontal disease. We hypothesize that chronic oral infection may be a previously unreported risk factor for the development of late-onset PVGI.
authors: Department of Microbiology, University Hospital of South Manchester, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK.
authors: Stephanie
authors: S
authors: Thomas
authors: Department of Vascular Surgery, University Hospital of South Manchester, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK.
authors: Jonathan
authors: J
authors: Ghosh
authors: Department of Vascular Surgery, University Hospital of South Manchester, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK.
authors: Johnathan
authors: J
authors: Porter
authors: Department of Vascular Surgery, University Hospital of South Manchester, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK.
authors: Adele
authors: A
authors: Cockcroft
authors: Department of Microbiology, University Hospital of South Manchester, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK ; The University of Manchester, Manchester Academic Health Science Centre, Institute of Inflammation and Repair, Oxford Road, Manchester M13 9PT, UK.
authors: Riina
authors: R
authors: Rautemaa-Richardson