title: Risk of abscess formation after liver tumor radiofrequency ablation: a review of 8 cases wtih a history of enterobiliary anastomosis.
abstract: OBJECTIVE
  Rates of postoperative complications after radiofrequency ablation (RFA) remain high for patients who have previously undergone surgery associated with the bile duct. Our purpose is to clarify the rate of postoperative complication and identify preoperative risk factors.
  
  
  METHODS
  This retrospective study reviewed patient backgrounds, ablation areas, and preoperative laboratory data in 8 patients (9 tumors) who underwent RFA after enterobiliary anastomosis.
  
  
  RESULTS
  Postoperative complications occurred in 6 of the 8 cases (75%). Postoperative liver abscesses occurred in both the cases of tumor located in the hepatic hilum, i.e., tumor located 5–30 mm from the site of enterobiliary anastomosis. Of the 6 patients with peripherally located tumors, postoperative liver abscesses occurred in 4 patients with elevated preoperative levels of alkaline phosphate (ALP), 3 of whom required abscess drainage. No postoperative complications occurred in the 2 patients with tumors located in the periphery of the liver and with normal preoperative ALP levels.
  
  
  CONCLUSIONS
  Postoperative complications are frequent when RFA is performed in patients who have previously undergone enterobiliary anastomosis. These results suggest that RFA after enterobiliary anastomosis should not be recommended. However, the risk may be lower in cases where the nodules are located in the liver periphery and the preoperative ALP level is low.
authors.forename: Hiroya
authors.initials: H
authors.lastname: Iida
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Aihara
authors.forename: Shinichi
authors.initials: S
authors.lastname: Ikuta
authors.forename: Naoki
authors.initials: N
authors.lastname: Yamanaka
mesh_terms: D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood; D000714:Anastomosis, Surgical; D001662:Biliary Tract Surgical Procedures / Q000009:adverse effects*; D014408:Biomarkers, Tumor / Q000097:blood; D017115:Catheter Ablation / Q000009:adverse effects*; D004322:Drainage; D005260:Female; D006801:Humans; D008100:Liver Abscess / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008113:Liver Neoplasms / Q000097:blood / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D000469:Alkaline Phosphatase