title: [Computed tomography in the assessment of causes of restrictive lung disorders in patients with pulmonary histiocytosis X].
abstract: OBJECTIVE
  To estimate the capabilities of computed tomography (CT) in revealing the anatomic causes of restrictive lung changes in patients with pulmonary histiocytosis X.
  
  
  METHODS
  The results of examining 36 patients with pulmonary histiocytosis X, who underwent comprehensive functional study of external respiration (CRSER), CT, and high-performance CT (HPCT), were analyzed.
  
  
  RESULTS
  According to the results of CRSER, the authors identified a group of patients with restrictive ventilation disorders, which included 7 men and 1 woman. The most common cause of restrictive disorders was generalized fibrous changes in lung tissue, which fails to result in its expansion. Multiple cysts were another cause of restrictive disorders in 2 patients. Fusion of individual cysts into large ones and the formation of a great number of paradoxically ventilated cysts were the third cause of restrictive disorders in pulmonary histiocytosis X, which was identified during HPCT.
  
  
  CONCLUSIONS
  Comprehensive morphofunctional examination involving CRSER and high-resolution CT can reveal the unfavorable course of pulmonary histiocytosis X with the restrictive type of lesion.
authors.forename: A A
authors.initials: AA
authors.lastname: Speranskaia
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Kameneva
authors.forename: L N
authors.initials: LN
authors.lastname: Novikova
authors.forename: V V
authors.initials: VV
authors.lastname: Amosov
authors.forename: M A
authors.initials: MA
authors.lastname: Vasil'eva
mesh_terms: D000328:Adult; D003560:Cysts / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology; D003937:Diagnosis, Differential; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008297:Male; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology; D015203:Reproducibility of Results; D012129:Respiratory Function Tests / Q000379:methods; D012189:Retrospective Studies; D012426:Russia; D014057:Tomography, X-Ray Computed / Q000379:methods*