title: Obstructive jaundice by lymph node recurrence of gastric cancer: can surgical derivation still play a role?
abstract: OBJECTIVE
  In some cases of bile duct compression by lymph node recurrence of gastric cancer, a second line chemotherapy can lead to prolonged survival; thus, a surgical derivation could represent a reasonable alternative to non surgical drainage, owing to its better long term efficacy. Our study retrospectively compares the surgical approach (SA) and percutaneous transhepatic biliary drainage (PTBD) in this particular oncological condition.
  
  
  METHODS
  11 patients undergoing biliary-jejunal anastomosis for obstructive jaundice by lymph node recurrence of gastric cancer at our Institution were compared with 10 patients undergoing PTBD. Clinical records and outcome parameters (success rate, complications, survival) were statistically matched in order to assess possible advantages for each technique and to evaluate any particular variable influencing survival.
  
  
  RESULTS
  The SA patients experienced a better jaundice resolution (91% vs 50%, p.0.063), a lower major complication rate (9% vs 30%, p:0.311), and a significantly longer survival (317 days vs 85 days, p:0.001). Procedural success and complication rates were found to be correlated with survival.
  
  
  CONCLUSIONS
  According to our experience the SA represents a valid alternative to PTBD in the case of lymph node recurrence of gastric cancer, being favoured for patients with better performance status and longer life expectancy.
authors.forename: Federico
authors.initials: F
authors.lastname: Marchesi
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Mita
authors.forename: Stefano
authors.initials: S
authors.lastname: Cecchini
authors.forename: Antonio
authors.initials: A
authors.lastname: Ziccarelli
authors.forename: Emanuele
authors.initials: E
authors.lastname: Michieletti
authors.forename: Paolo
authors.initials: P
authors.lastname: Del Rio
authors.forename: Luigi
authors.initials: L
authors.lastname: Roncoroni
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004322:Drainage; D005260:Female; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology / Q000601:surgery*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology*