title: A universal sensing platform based on the repair ligation-mediated light-producing DNA machine.
abstract: The repair ligation-mediated light-producing DNA machine can produce light through transforming the repetitive DNA cleavage/ligation motions into optical energy without the requirement of either external reporting reagents or excitation light, and it can be applied for sensitive and selective detection of DNA, thrombin, adenosine, potassium ions (K(+)) and endonuclease even in human serum.
authors.affiliation: Single-Molecule Detection and Imaging Laboratory, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China. zhangcy@siat.ac.cn.
authors.forename: Qinfeng
authors.initials: Q
authors.lastname: Xu
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Chun-yang
authors.initials: CY
authors.lastname: Zhang
mesh_terms: D000241:Adenosine / Q000097:blood; D004247:DNA / Q000097:blood*; D053837:DNA Cleavage; D006801:Humans; D006868:Hydrolysis; D008027:Light; D009243:NAD / Q000737:chemistry; D011188:Potassium / Q000097:blood; D013917:Thrombin / Q000032:analysis
chemical_list: D009243:NAD; D004247:DNA; D013917:Thrombin; D000241:Adenosine; D011188:Potassium