title: Frequency and temperature dependence of skin bioimpedance during a contralateral cold test.
abstract: A study of the α- and β-dispersion of skin bioimpedance dependence on temperature and micro-hemodynamics is presented. The vascular tone changes during the cold test are verified by the wavelet-analysis of skin temperature signals obtained simultaneously with impedance measurements. Thirty three normal healthy subjects of 28  ±  7 years old were entered into the study. The tetra-polar electrode system was used to record the resistance and reactance; measurements were carried out at 67 frequencies, in a frequency range from 2 Hz to 50 kHz. It has been found that the impedance decreases with vasodilation and increases with vasoconstriction. The high values of correlation among thermal oscillation amplitudes and Nyquist diagram parameters prove the impedance dependence on blood flow in three frequency bands corresponding to the myogenic, neurogenic and endothelial vascular tone regulation mechanisms. Using an equivalent RC circuit, we obtained the changes in the Nyquist diagram matching the experimental data. The proposed descriptive α-dispersion model can be used to study mechanisms responsible for intercellular interaction.
authors.affiliation: Institute of Continuous Media Mechanics, Korolyov str.1, Perm 614013, Russia.
authors.forename: S
authors.initials: S
authors.lastname: Podtaev
authors.forename: D
authors.initials: D
authors.lastname: Nikolaev
authors.forename: V
authors.initials: V
authors.lastname: Samartsev
authors.forename: V
authors.initials: V
authors.lastname: Gavrilov
authors.forename: K
authors.initials: K
authors.lastname: Tsiberkin
mesh_terms: D000328:Adult; D003080:Cold Temperature; D058266:Dielectric Spectroscopy; D017097:Electric Impedance; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D012039:Regional Blood Flow / Q000502:physiology; D012879:Skin Physiological Phenomena; D012984:Software; D062125:Thermometry; D014661:Vasoconstriction / Q000502:physiology; D014664:Vasodilation / Q000502:physiology