title: [Study of echocardiographic parameters of rheumatoid arthritis black African without clinically evident cardiovascular manifestations: A cross-sectional study of 73 cases in Senegal].
abstract: BACKGROUND
  Research of cardiac involvement in patients with rheumatoid arthritis can prevent complications and place in a logical secondary prevention. The objective of this study was to investigate the echocardiographic parameters in a population of Senegalese patients with rheumatoid arthritis without clinically evident cardiovascular manifestations.
  
  
  METHODS
  We conducted a descriptive cross-sectional study, which included prospectively from outpatients in the internal medicine department of university hospital center Aristide Le Dantec in Dakar, Senegal, with a diagnosis of rheumatoid arthritis without clinically evident cardiovascular disease. It focused on a sample of 73 patients of both sexes aged at least 18 years. Following clinical examination, we conducted laboratory tests (CRP, fibrinogen, ESR, rheumatoid factors: Latex and Waaler-Rose, anti-CCP, antinuclear factors and anti-ENA antibodies), ECG, echocardiography standard. Data were analyzed using a descriptive study of the different variables with the calculation of proportions for categorical variables, and the positional parameters and dispersion for quantitative variables.
  
  
  RESULTS
  A total of 73 patients with rheumatoid arthritis without obvious cardiac events and meeting the criteria of definition of the ACR 1987 were included in the study. The mean age was 44.17±14.43 years with extremes of 18 and 75 years. The mean duration of RA was 5.93±4.78 years. The concept of family inflammatory arthritis was reported in 35.60% of cases and almost one in six patients had at least a factor of cardiovascular risk (16.96%). The abnormalities found in Doppler echocardiography were dominated by diastolic LV dysfunction (42.46%), increased left ventricular mass in 35.61%. Valvular leaks of variable grades were highlighted regarding all orifices but were rarely significant.
  
  
  CONCLUSIONS
  The realization of echocardiography in patients with rheumatoid arthritis without clinically evident cardiovascular manifestations helps to highlight cardiovascular abnormalities related to the natural course of the disease.
authors.affiliation: Service de cardiologie, hôpital Aristide Le Dantec, Dakar, Sénégal. Electronic address: nazdodo@yahoo.fr.
authors.forename: M N
authors.initials: MN
authors.lastname: Dodo-Siddo
authors.affiliation: Service de cardiologie, hôpital Aristide Le Dantec, Dakar, Sénégal.
authors.forename: M
authors.initials: M
authors.lastname: Diao
authors.affiliation: Service de cardiologie, hôpital Aristide Le Dantec, Dakar, Sénégal.
authors.forename: M B
authors.initials: MB
authors.lastname: Ndiaye
authors.affiliation: Service de médecine interne, hôpital Aristide Le Dantec, Dakar, Sénégal.
authors.forename: S
authors.initials: S
authors.lastname: Ndongo
authors.affiliation: Service de cardiologie, hôpital Aristide Le Dantec, Dakar, Sénégal.
authors.forename: A
authors.initials: A
authors.lastname: Kane
authors.affiliation: Service de cardiologie, hôpital général de Grand-Yoff, Dakar, Sénégal.
authors.forename: A
authors.initials: A
authors.lastname: Mbaye
authors.affiliation: Service de cardiologie, hôpital Aristide Le Dantec, Dakar, Sénégal.
authors.forename: M
authors.initials: M
authors.lastname: Bodian
authors.affiliation: Service de cardiologie, hôpital Aristide Le Dantec, Dakar, Sénégal.
authors.forename: S A
authors.initials: SA
authors.lastname: Sarr
authors.affiliation: Service de cardiologie, hôpital Aristide Le Dantec, Dakar, Sénégal.
authors.forename: M
authors.initials: M
authors.lastname: Sarr
authors.affiliation: Service de cardiologie, hôpital Aristide Le Dantec, Dakar, Sénégal.
authors.forename: S
authors.initials: S
authors.lastname: Ba
authors.affiliation: Service de médecine interne, hôpital Aristide Le Dantec, Dakar, Sénégal.
authors.forename: T M
authors.initials: TM
authors.lastname: Diop
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000175:diagnosis* / Q000208:ethnology / Q000503:physiopathology*; D044383:Black People / Q000208:ethnology; D003430:Cross-Sectional Studies; D004452:Echocardiography / Q000379:methods; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012307:Risk Factors; D012675:Senegal / Q000208:ethnology; D012680:Sensitivity and Specificity; D018487:Ventricular Dysfunction, Left / Q000503:physiopathology*; D055815:Young Adult
keywords: Aspects électrocardiographiques et échocardiographiques; Asymptomatic cardiovascular level; Asymptomatique au plan cardiovasculaire; Electrocardiographic and echocardiographic aspects; Polyarthrite rhumatoïde; Rheumatoid arthritis