title: CCR 20th Anniversary commentary: stayin' alive-antiapoptotic proteins and breast cancer.
abstract: The control of cell death involves a complex interaction of multiple proteins. In a study published in the January 1, 2000, issue of Clinical Cancer Research, Tanaka and colleagues demonstrated that one of the proapoptotic proteins, survivin, was frequently expressed in breast cancer. In the subsequent years, effectors of apoptosis have translated into important prognostic indicators and potential therapeutic targets.
authors.affiliation: Masonic Cancer Center, Department of Medicine, University of Minnesota, Minneapolis, Minnesota. yeexx006@umn.edu.
authors.forename: Douglas
authors.initials: D
authors.lastname: Yee
mesh_terms: D000846:Anniversaries and Special Events; D017209:Apoptosis / Q000502:physiology*; D051017:Apoptosis Regulatory Proteins / Q000378:metabolism*; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans
chemical_list: D051017:Apoptosis Regulatory Proteins