title: Clinical study of transcanal closure of tympanic membrane perforations using a collagen sponge.
abstract: METHODS
  We used an artificial dermis (Terdermis), which is an atero-collagen sponge covered with a sheet of silicon.
  
  
  METHODS
  Nineteen ears of 17 patients with perforation of the tympanic membrane under various conditions, including large and wet perforations, underwent operation using this collagen sponge.
  
  
  RESULTS
  The success rate of closure after the initial surgery was 8/19. The overall success rate of closure after initial and re-operation was 14/19. The success rate of closure was 12/14 for small-sized perforations, 1/4 for middle-sized perforations and 1/1 for a large-sized perforation. Middle- and large-sized perforations required multiple surgeries. The success rate of closure was 11/11 for dry perforations, 3/4 for perforations with light otorrhoea and 0/4 for perforations with extensive otorrhoea.
  
  
  CONCLUSIONS
  This surgery is a low-cost and minimally invasive surgery and has a high closure rate. This surgery is effective on small-sized, dry perforations although it can also close middle- and large-sized dry perforations.
authors.affiliation: Department of Otolaryngology,Hamanomachi Hospital,Fukuoka,Japan.
authors.forename: A
authors.initials: A
authors.lastname: Tamae
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: S
authors.initials: S
authors.lastname: Komune
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003094:Collagen / Q000627:therapeutic use*; D004424:Ear Canal / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D009225:Myringoplasty / Q000379:methods*; D016896:Treatment Outcome; D018058:Tympanic Membrane Perforation / Q000601:surgery*
chemical_list: D003094:Collagen
keywords: Collagen Sponge