title: Dynamic magnetic resonance imaging evaluation of pelvic reconstruction with porcine dermal collagen mesh following extra-levator abdominoperineal excision for primary rectal cancer.
abstract: OBJECTIVE
  Extra-levator abdominoperineal excision for rectal cancer includes resection of the levator ani muscle and therefore makes pelvic reconstruction advisable. The aim of our study was to evaluate morphologic and functional long-term results of pelvic floor augmentation with porcine dermal collagen mesh by dynamic magnetic resonance imaging and clinical examination.
  
  
  METHODS
  Twenty consecutive patients underwent perineal reconstruction with porcine dermal collagen mesh following extra-levator abdominoperineal excision for primary rectal adenocarcinoma with curative intent between 2009 and 2012. Patient perioperative and postoperative data were collected prospectively. There were one cancer-related and two noncancer-related deaths in the follow-up period, and another three patients refused the dynamic magnetic resonance imaging.
  
  
  RESULTS
  Fourteen patients were included in the study. The median time period from surgery to dynamic magnetic resonance imaging and clinical examination was 31 months (range 19-56). Wound infections were observed in 43% (6 of 14) of these patients in the postoperative period, but no mesh had to be removed. No focal mesh defect, no damage on the suture line, and no perineal hernia were detected on dynamic magnetic resonance imaging. Clinical examination revealed no pathological findings in any patient.
  
  
  CONCLUSIONS
  The implantation of a porcine dermal collagen mesh is an effective and reliable option for pelvic floor reconstruction after extra-levator abdominoperineal excision. Despite a high incidence of primary wound infections, the healing rate was satisfactory, no mesh had to be removed, and long-term stability could be achieved.
authors.affiliation: Department of Surgery, Paracelsus Medical University, Muellner Hauptstraße 48, 5020, Salzburg, Austria, a.dinnewitzer@salk.at.
authors.forename: Adam
authors.initials: A
authors.lastname: Dinnewitzer
authors.forename: Matthias
authors.initials: M
authors.lastname: Meissnitzer
authors.forename: Thomas
authors.initials: T
authors.lastname: Meissnitzer
authors.forename: Clemens
authors.initials: C
authors.lastname: Nawara
authors.forename: Christoph
authors.initials: C
authors.lastname: Augschöll
authors.forename: Selina
authors.initials: S
authors.lastname: Buchner
authors.forename: Franz
authors.initials: F
authors.lastname: Mayer
authors.forename: Dietmar
authors.initials: D
authors.lastname: Öfner
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology / Q000601:surgery*; D017773:Pelvic Floor / Q000473:pathology* / Q000601:surgery*; D010502:Perineum / Q000601:surgery; D012004:Rectal Neoplasms / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D013526:Surgical Mesh; D013530:Surgical Wound Infection / Q000503:physiopathology; D013552:Swine; D014945:Wound Healing