title: [Seasonal and individual characteristics of the blood fibrinolytic system reaction to the physical load].
abstract: 33 untrained test subjects (16 males and 17 females aged 18) have been studied for one year for their blood fibrinolysis reaction to a one-time 20-minute bicycle-ergometric large-capacity load (N male = 2.66 watt/kg, N female = 2.3 watt/kg). It is known that at rest the blood fibrinolytic activity (FA) has its seasonal characteristics: it is relatively high in the autumn and spring and low in the winter and summer. On the average, in the winter and in the summer physical activity stimulates the blood clot lysis whereas in the autumn and in the spring it does not. The direction and the intensity of the fibrinolysis system response to work have individual features: in the autumn and in the spring they are connected with its initial state (they increase when the blood FA is low and decrease when the blood FA is high) as well as they have large fluctuations, whereas in the winter and in the summer they are not subject to these laws. According to the parameters of the directional response to the load and its permanence there are three types of response: a) Hyperfibrinolytic, which is characterized by the FA increase when there is a physical load applied in all seasons of the year, having a low initial FA level at rest; b) Hypofibrinolytic, the representatives of which have a stable reaction of fibrinolysis oppression when there is a physical load applied, not depending on the season of the year and the initial level, having a high initial level of FA in the autumn and in the spring and low--in the winter and in the summer; c) Unstable, in which the direction of the fibrinolysis system response to the physical exercises is variable. The conclusion is that the development of thromboembolic complications as a consequence of having a physical load is most likely to be expected from those who have a hypofibrinolytic type of reaction while this is very unlikely to be expected from the representatives of the hyperfibrinolytic type.
authors.forename: S P
authors.initials: SP
authors.lastname: Golyshenkov
authors.forename: E A
authors.initials: EA
authors.lastname: Iakimova
mesh_terms: D000293:Adolescent; D015444:Exercise / Q000502:physiology*; D005260:Female; D005342:Fibrinolysis / Q000502:physiology*; D006801:Humans; D008297:Male; D012621:Seasons