title: Men and women from the STRIDE clinical trial: An assessment of stimulant abstinence symptom severity at residential treatment entry.
abstract: OBJECTIVE
  Gender-specific factors associated with stimulant abstinence severity were examined in a stimulant abusing or dependent residential treatment sample (N = 302).
  
  
  METHODS
  Bivariate statistics tested gender differences in stimulant abstinence symptoms, measured by participant-reported experiences of early withdrawal. Multivariate linear regression examined gender and other predictors of stimulant abstinence symptom severity.
  
  
  RESULTS
  Women compared to men reported greater stimulant abstinence symptom severity. Anxiety disorders and individual anxiety-related abstinence symptoms accounted for this difference. African American race/ethnicity was predictive of lower stimulant abstinence severity.
  
  
  CONCLUSIONS
  Women were more sensitive to anxiety-related stimulant withdrawal symptoms.
  
  
  CONCLUSIONS
  Clinics that address anxiety-related abstinence symptoms, which more commonly occur in women, may improve treatment outcome.
authors.affiliation: Virginia Commonwealth University, School of Social Work and Department of Psychiatry, Richmond, Virginia.
authors.forename: Karen G
authors.initials: KG
authors.lastname: Chartier
authors.forename: Katherine
authors.initials: K
authors.lastname: Sanchez
authors.forename: Therese K
authors.initials: TK
authors.lastname: Killeen
authors.forename: Allison
authors.initials: A
authors.lastname: Burrow
authors.forename: Thomas
authors.initials: T
authors.lastname: Carmody
authors.forename: Tracy L
authors.initials: TL
authors.lastname: Greer
authors.forename: Madhukar H
authors.initials: MH
authors.lastname: Trivedi
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000139:chemically induced / Q000175:diagnosis; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010343:Patient Admission; D012114:Residential Treatment; D012737:Sex Factors; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis*; D019966:Substance-Related Disorders / Q000188:drug therapy
chemical_list: D000697:Central Nervous System Stimulants
keywords: anxiety; early withdrawal symptoms; gender; stimulant abstinence severity