title: Protein lipid modifications and the regulation of ROP GTPase function.
abstract: In eukaryotes, the RHO superfamily of small G-proteins is implicated in the regulation of cell polarity and growth. Rho of Plants (ROPs)/RACs are plant-specific Rho family proteins that have been shown to regulate cell polarity, auxin transport and responses, ABA signalling, and response to pathogens. A hallmark of ROP/RAC function is their localization in specific plasma membrane domains. This short review focuses on the mechanisms responsible for membrane interactions of ROPs/RACs and how they affect ROP/RAC function.
authors.affiliation: Department of Molecular Biology and Ecology of Plants, Tel Aviv University, Tel Aviv 69978, Israel shauly@tauex.tau.ac.il.
authors.forename: Shaul
authors.initials: S
authors.lastname: Yalovsky
mesh_terms: D002462:Cell Membrane / Q000378:metabolism; D050356:Lipid Metabolism; D020559:Monomeric GTP-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000235:genetics / Q000378:metabolism*
chemical_list: D010940:Plant Proteins; D020559:Monomeric GTP-Binding Proteins
keywords: Cell polarity; RAC; ROP; Rho; S-acylation; membrane association; palmitoylation; prenylation; subcellular targeting.