title: Facile synthesis of nitrogen-doped carbon dots for Fe(3+) sensing and cellular imaging.
abstract: A fast and facile approach to synthesize highly nitrogen (N)-doped carbon dots (N-CDs) by microwave-assisted pyrolysis of chitosan, acetic acid and 1,2-ethylenediamine as the carbon source, condensation agent and N-dopant, respectively, is reported. The obtained N-CDs are fully characterized by elemental analysis, transmission electron microscopy, high-resolution transmission electron microscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, X-ray diffraction pattern, X-ray photoelectron spectroscopy, UV-vis absorption, and photoluminescence spectroscopy. Doping N heteroatoms benefits the generation of N-CDs with stronger fluorescence emission. As the emission of N-CDs is efficiently quenched by Fe(3+), the as-prepared N-CDs are employed as a highly sensitive and selective probe for Fe(3+) detection. The detection limit can reach as low as 10 ppb, and the linear range is 0.010-1.8 ppm Fe(3+). The as-synthesized N-CDs have been successfully applied for cell imaging and detecting Fe(3+) in biosystem.
authors.affiliation: Institute of Environmental Science, and School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China.
authors.forename: Xiaojuan
authors.initials: X
authors.lastname: Gong
authors.affiliation: Institute of Environmental Science, and School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China.
authors.forename: Wenjing
authors.initials: W
authors.lastname: Lu
authors.affiliation: Partner State Key Laboratory of Environmental and Biological Analysis, and Department of Chemistry, Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong SAR, China.
authors.forename: Man Chin
authors.initials: MC
authors.lastname: Paau
authors.affiliation: Partner State Key Laboratory of Environmental and Biological Analysis, and Department of Chemistry, Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong SAR, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Hu
authors.affiliation: Institute of Environmental Science, and School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wu
authors.affiliation: Institute of Environmental Science, and School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China.
authors.forename: Shaomin
authors.initials: S
authors.lastname: Shuang
authors.affiliation: Institute of Environmental Science, and School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, China. Electronic address: dc@sxu.edu.cn.
authors.forename: Chuan
authors.initials: C
authors.lastname: Dong
authors.affiliation: Partner State Key Laboratory of Environmental and Biological Analysis, and Department of Chemistry, Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong SAR, China. Electronic address: mmfchoi@gmail.com.
authors.forename: Martin M F
authors.initials: MM
authors.lastname: Choi
mesh_terms: D001672:Biocompatible Materials; D002244:Carbon / Q000737:chemistry*; D005290:Ferric Compounds / Q000032:analysis*; D046529:Microscopy, Electron, Transmission; D009584:Nitrogen / Q000737:chemistry*; D013057:Spectrum Analysis / Q000379:methods
chemical_list: D001672:Biocompatible Materials; D005290:Ferric Compounds; D002244:Carbon; D009584:Nitrogen
keywords: Cell image; Chitosan; EDA; Fe(3+) detection; Nitrogen-doped carbon dots