title: [Spontaneous mutation rate changes in saccharomyces cerevisiae at combinations of hsm3 and hsm6 mutations with rad52 mutation].
abstract: Long-term storage at +4 degrees C and cultivation at +30 degrees C changes the spontaneous mutation rate of the yeast Saccharomyces cerevisiae double mutants rad52hsm3delta and rad52hsm6-1. Combinations of hsm3 and hsm6 mutations with the rad52 mutation lead to a decrease of the spontaneous mutation rate mediated by DNA repair synthesis in multiply replanted strains in comparison with the same strains investigated right after RAD52 gene decay. Combinations of hsm3 and hsm6 mutations with mutations in other genes of the RAD52 epistatic group did not provide a spontaneous mutation rate decrease.
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Chernenkov
authors.forename: D V
authors.initials: DV
authors.lastname: Fedorov
authors.forename: A A
authors.initials: AA
authors.lastname: Kosareva
authors.forename: T N
authors.initials: TN
authors.lastname: Kozhina
authors.forename: V G
authors.initials: VG
authors.lastname: Korolev
mesh_terms: D004260:DNA Repair / Q000235:genetics; D004261:DNA Replication / Q000235:genetics; D018832:Molecular Chaperones / Q000235:genetics*; D009154:Mutation; D059645:Mutation Rate; D051721:Rad52 DNA Repair and Recombination Protein / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics*; D013696:Temperature
chemical_list: C112193:HSM3 protein, S cerevisiae; D018832:Molecular Chaperones; C497197:RAD52 protein, S cerevisiae; D051721:Rad52 DNA Repair and Recombination Protein; D029701:Saccharomyces cerevisiae Proteins