title: Magnified endoscopic features of duodenal follicular lymphoma and other whitish lesions.
abstract: The sensitivity and specificity of magnified endoscopic features for differentiating follicular lymphoma from other diseases with duodenal whitish lesions have never been investigated. Here we compared the magnified endoscopic features of duodenal follicular lymphoma with those of other whitish lesions. We retrospectively reviewed the cases of patients with follicular lymphoma (n＝9), lymphangiectasia (n＝7), adenoma (n＝10), duodenitis (n＝4), erosion (n＝1), lymphangioma (n＝1), and hyperplastic polyp (n＝1). The magnified features of the nine follicular lymphomas included enlarged villi (n＝8), dilated microvessels (n＝5), and opaque white spots of various sizes (n＝9). The lymphangiectasias showed enlarged villi, dilated microvessels, and white spots, but the sizes of the white spots were relatively homogeneous and their margin was clear. Observation of the adenoma and duodenitis revealed only whitish villi. Although the lymphangioma was indistinguishable from the follicular lymphomas by magnified features, it was easily diagnosed based on the macroscopic morphology. In conclusion, magnified endoscopic features, in combination with macroscopic features, are useful for differentiating follicular lymphomas from other duodenal diseases presenting whitish lesions.
authors.affiliation: Department of Molecular Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.iwamuromasaya@yahoo.co.jp.
authors.forename: Masaya
authors.initials: M
authors.lastname: Iwamuro
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Okada
authors.forename: Katsuyoshi
authors.initials: K
authors.lastname: Takata
authors.forename: Yoshinari
authors.initials: Y
authors.lastname: Kawai
authors.forename: Seiji
authors.initials: S
authors.lastname: Kawano
authors.forename: Junichiro
authors.initials: J
authors.lastname: Nasu
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Kawahara
authors.forename: Takehiro
authors.initials: T
authors.lastname: Tanaka
authors.forename: Tadashi
authors.initials: T
authors.lastname: Yoshino
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Yamamoto
mesh_terms: D000368:Aged; D004379:Duodenal Neoplasms / Q000473:pathology*; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D008224:Lymphoma, Follicular / Q000473:pathology*; D008297:Male; D008875:Middle Aged