title: Recently completed trials on the drug treatment of hypertension: comments on ALLHAT and ANBP-2.
abstract: Recently the results of two important large-scale studies on hypertension management were published and intensely debated: ALLHAT and ANBP-2. In particular the ALLHAT study was discussed and subjected to criticism. The positive and negative aspects of this study are the subject of the present survey. ALLHAT has reemphasised the important role of thiazide diuretics in the treatment of hypertension. However, there should also be an important position for the various other well-known drugs such as β-blockers, ACE inhibitors, calcium antagonists and AT1-blockers (sartans). The choice of the drug(s) to be prescribed is largely determined by the comorbidity, which occurs frequently in elderly hypertensives. Furthermore, combination therapy is applied more and more frequently.
authors.forename: P A
authors.initials: PA
authors.lastname: van Zwieten
keywords: ALLHAT; ANBP-2; drug treatment; hypertension; thiazides