title: Reference Ranges in [(99m)Tc]Mercaptoacetyltriglycerine Renography: Comparison of a Semi-automated (Xeleris, GE) and Manual (Picker, Odyssey) Processing Software.
abstract: OBJECTIVE
  The purpose of the study was to define reference ranges for quantitative parameters in [(99m)Tc]mercaptoacetyltriglycerine ([(99m)Tc]MAG3) renography to assist interpretation in a semi-automated (Xeleris, GE) compared to a manual (Picker, Odyssey) software package.
  
  
  METHODS
  Forty-eight subjects approved for renal donation were evaluated with [(99m)Tc]MAG3 renography using both the Xeleris and the Picker software.
  
  
  RESULTS
  Reference ranges for the two software were comparable regarding the relative function of the two kidneys (the split function, SF) and the residual activities (RA). The time to peak whole-kidney activities (T max whole-kidney) was more dependent on the type of software. Using Bland-Altman limits, we found good and acceptable agreement between the two methods.
  
  
  CONCLUSIONS
  We found good correlation between renography results using the Xeleris and Picker software packages. However, software-specific reference ranges are needed.
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, 5000, Odense, Denmark. kate.rewers@rsyd.dk.
authors.forename: Kate I
authors.initials: KI
authors.lastname: Rewers
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, 5000, Odense, Denmark.
authors.forename: Svend
authors.initials: S
authors.lastname: Hvidsten
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, 5000, Odense, Denmark.|Centre of Health Economics Research, University of Southern Denmark, Odense, Denmark.
authors.forename: Oke
authors.initials: O
authors.lastname: Gerke
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, 5000, Odense, Denmark.
authors.forename: Søren
authors.initials: S
authors.lastname: Schifter
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007668:Kidney / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011866:Radioisotope Renography / Q000379:methods* / Q000592:standards; D012016:Reference Values; D012984:Software; D017263:Technetium Tc 99m Mertiatide / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D017263:Technetium Tc 99m Mertiatide
keywords: ROI; Reference range; Tc-99m-MAG3 renography