title: Endobronchial biopsies on aspirin and prasugrel.
abstract: Patients are generally required to stop antiplatelet therapy prior to elective invasive procedures. Some patients receive dual antiplatelet therapy for recent vascular procedures such as drug-eluting coronary stenting, and early discontinuation of antiplatelet agents could lead to a significant risk of stent thrombosis. Most bronchoscopic procedures are performed on patients using Aspirin but not on those using Clopidogrel or Prasugrel. In this report, we describe a unique case of a patient with a recent placement of drug-eluting stents, who required endobronchial biopsies for evaluation of lung cancer recurrence. The procedure was performed successfully and safely with no complications.
authors.affiliation: Roswell Park Cancer Institute, Department of Medicine, Interventional Pulmonary section, Buffalo, NY, USA; Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University at Buffalo, State University of New York, NY, USA. Electronic address: kassemharris@gmail.com.
authors.forename: Kassem
authors.initials: K
authors.lastname: Harris
authors.affiliation: Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University at Buffalo, State University of New York, NY, USA.
authors.forename: Jad
authors.initials: J
authors.lastname: Kebbe
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000379:methods; D001241:Aspirin / Q000008:administration & dosage* / Q000009:adverse effects; D001707:Biopsy, Needle; D001999:Bronchoscopy / Q000379:methods*; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D023903:Coronary Restenosis / Q000188:drug therapy / Q000517:prevention & control*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000628:therapy; D054855:Drug-Eluting Stents; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D061214:Patient Safety; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000009:adverse effects; D011013:Pneumonectomy / Q000379:methods; D000068799:Prasugrel Hydrochloride / Q000008:administration & dosage* / Q000009:adverse effects; D011859:Radiography; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D010975:Platelet Aggregation Inhibitors; D000068799:Prasugrel Hydrochloride; D001241:Aspirin
keywords: Aspirin; Bleeding; Bronchoscopy; Endobronchial biopsy; Prasugrel