title: Renal diseases in adults with cystic fibrosis: a 40 year single centre experience.
abstract: BACKGROUND
  There is a sizable literature describing renal disease in patients with cystic fibrosis. Previous studies have focused on single disease processes alone, most commonly renal stone disease or acute kidney injury. In this study we report for the first time on the prevalence of all forms of renal disease in a cystic fibrosis population.
  
  
  METHODS
  A retrospective review of adult patients with cystic fibrosis attending the Adult Cystic Fibrosis Department at the Royal Brompton Hospital was carried out by searching the department's database to identify patients with renal problems and subsequently retrieving clinical information from medical notes.
  
  
  RESULTS
  The prevalence of all renal diseases in our population was 5.1 %. The most commonly identified problem was renal stones. At 2.0 % the prevalence of renal stones in adult patients with cystic fibrosis was comparable to the general population. A range of other renal diseases were identified, the next most common being drug-induced acute kidney injury.
  
  
  CONCLUSIONS
  A range of cystic fibrosis independent and attributable diseases has been identified but no cystic fibrosis specific disease. In contrast to other cystic fibrosis centres no increased prevalence of renal stones was found.
authors.affiliation: Department of Cystic Fibrosis, Royal Brompton Hospital, London, UK. mjwilcock@doctors.org.uk.|Oxford Kidney Unit, Churchill Hospital, Old Road, Oxford, UK. mjwilcock@doctors.org.uk.
authors.forename: M J
authors.initials: MJ
authors.lastname: Wilcock
authors.affiliation: Department of Cystic Fibrosis, Royal Brompton Hospital, London, UK.
authors.forename: A
authors.initials: A
authors.lastname: Ruddick
authors.affiliation: Department of Cystic Fibrosis, Royal Brompton Hospital, London, UK.
authors.forename: K M
authors.initials: KM
authors.lastname: Gyi
authors.affiliation: Department of Cystic Fibrosis, Royal Brompton Hospital, London, UK.
authors.forename: M E
authors.initials: ME
authors.lastname: Hodson
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D005544:Forecasting; D006801:Humans; D007674:Kidney Diseases / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult
keywords: Acute kidney injury; Chronic kidney disease; Cystic fibrosis; Renal stones