title: Interpreting guidance on significant changes.
mesh_terms: D000288:Administrative Personnel; D035661:Animal Care Committees; D000827:Animal Welfare / Q000592:standards*; D000818:Animals; D019983:Guideline Adherence; D017408:Guidelines as Topic; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL