title: Construction of stable polymeric vesicles based on azobenzene and beta-cyclodextrin grafted poly(glycerol methacrylate)s for potential applications in colon-specific drug delivery.
abstract: Polymeric vesicles constructed from cyclodextrin- and azobenzene-grafted poly(glycidyl methacrylate)s showed excellent stability owing to the multiple host-guest complexation. Upon culturing in Na2S2O4-contained buffer solution, cargo-loaded vesicles disassembled, for potential applications in colon-specific drug delivery.
authors.affiliation: School of Chemistry and Chemical Engineering, Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, Tianjin University of Technology, Tianjin 300384, P. R. China. hgao@tjut.edu.cn.
authors.forename: Wen-Xing
authors.initials: WX
authors.lastname: Gu
authors.forename: Qing-Lan
authors.initials: QL
authors.lastname: Li
authors.forename: Hongguang
authors.initials: H
authors.lastname: Lu
authors.forename: Lei
authors.initials: L
authors.lastname: Fang
authors.forename: Qixian
authors.initials: Q
authors.lastname: Chen
authors.forename: Ying-Wei
authors.initials: YW
authors.lastname: Yang
authors.forename: Hui
authors.initials: H
authors.lastname: Gao
mesh_terms: D001391:Azo Compounds / Q000737:chemistry*; D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000378:metabolism*; D016503:Drug Delivery Systems; D006801:Humans; D011109:Polymethacrylic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D001391:Azo Compounds; D001672:Biocompatible Materials; D011109:Polymethacrylic Acids; D047392:beta-Cyclodextrins; C042535:polyglycidyl methacrylate; C009850:azobenzene; C031215:betadex