title: Full genome sequence of guinea fowl coronavirus associated with fulminating disease.
abstract: Guinea fowl coronavirus (GfCoV), a recently characterized avian coronavirus, was identified from outbreaks of fulminating disease (peracute enteritis) in guinea fowl in France. The full-length genomic sequence was determined to better understand its genetic relationship with avian coronaviruses. The full-length coding genome sequence was 26,985 nucleotides long with 11 open reading frames and no hemagglutinin-esterase gene: a genome organization identical to that of turkey coronavirus [5' untranslated region (UTR)-replicase (ORFs 1a, 1ab)-spike (S) protein-ORF3 (ORFs 3a, 3b)-small envelop (E or 3c) protein-membrane (M) protein-ORF5 (ORFs 4b, 4c, 5a, 5b)-nucleocapsid (N) protein (ORFs N and 6b)-3' UTR]. This is the first complete genome sequence of a GfCoV and confirms that the new virus belongs to group gammacoronaviruses.
authors.affiliation: INRA, UMR 1225 and Université de Toulouse, INP, ENVT, 23 Chemin des Capelles, 31076, Toulouse, France, m.ducatez@envt.fr.
authors.forename: Mariette F
authors.initials: MF
authors.lastname: Ducatez
authors.forename: Etienne
authors.initials: E
authors.lastname: Liais
authors.forename: Guillaume
authors.initials: G
authors.lastname: Croville
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Guérin
mesh_terms: D000818:Animals; D001715:Bird Diseases / Q000821:virology*; D001717:Birds; D016000:Cluster Analysis; D017934:Coronavirus / Q000235:genetics* / Q000302:isolation & purification*; D018352:Coronavirus Infections / Q000662:veterinary* / Q000821:virology; D005602:France; D023061:Gene Order; D016679:Genome, Viral; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics*; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D026801:Synteny
chemical_list: D012367:RNA, Viral