title: Severe periodontal disease manifested in chronic disseminated type of langerhans cell histiocytosis in a 3-year old child.
abstract: Langerhans cell histiocytosis (LCH), previously known as histio-cytosis X, is a rare idiopathic disorder of reticulo-endothelial system with abnormal proliferation of bone marrow derived Langerhans cells along with a variable number of leukocytes, such as eosinophils, neutrophils, lymphocytes and plasma cells. Three years old male child presented with multifocal osteolytic lesions and papulosquamous skin lesions. Clinical and radio-graphic features, such as severe alveolar bone loss, mobility of teeth, precocious eruption of teeth, foating appearance of teeth in orthopantomogram (OPG), osteolytic lesion in skull and cutaneous lesions were highly suggestive of LCH disease. Skin biopsy confirmed a diagnosis of LCH. Induction chemotherapy with oral prednisolone and intravenous vinblastine was started. Child responded well to chemotherapy. The clinical significance of the presented case is to diagnose the case of LCH on the basis of the manifestation of severe periodontal disease as this can be first or only manifestation of LCH. A dentist plays a major role in the multidisciplinary treatment of LCH through routine examination and periodic follow-up. How to cite this article: Bansal M, Srivastava VK, Bansal R, Gupta V, Bansal M, Patne S. Severe Periodontal Disease Manifested in Chronic Disseminated Type of Langerhans Cell Histiocytosis in a 3-Year Old Child. Int J Clin Pediatr Dent 2014;7(3):217-219.
authors.affiliation: Assistant Professor, Department of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh India.
authors.forename: Monika
authors.initials: M
authors.lastname: Bansal
authors.affiliation: Associate Professor, Department of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh India.
authors.forename: Vinay Kumar
authors.initials: VK
authors.lastname: Srivastava
authors.affiliation: Reader, Department of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh India.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Bansal
authors.affiliation: Associate Professor, Department of Pediatrics, Faculty of Modern Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
authors.forename: Vineeta
authors.initials: V
authors.lastname: Gupta
authors.affiliation: Assistant Professor, Department of Skin, Faculty of Modern Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
authors.forename: Manish
authors.initials: M
authors.lastname: Bansal
authors.affiliation: Assistant Professor, Department of Pathology, Faculty of Modern Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
authors.forename: Shashikant
authors.initials: S
authors.lastname: Patne
keywords: Floating teeth; Langerhans cell histiocytosis; Oste-olytic lesion; Seborrheic dermatitis.