title: Squamous cell carcinoma of the oropharynx: single-institution outcome analysis of patients treated with concurrent chemoradiotherapy.
abstract: OBJECTIVE
  The object of this study was to analyse our experience with the effects of concurrent chemoradiotherapy for oropharyngeal squamous cell carcinoma, the treatment results of this therapeutic strategy and a salvage treatment for recurrent oropharyngeal squamous cell carcinoma.
  
  
  METHODS
  Seventy-five patients with oropharyngeal squamous cell carcinoma were treated with chemoradiotherapy. The study included twenty-five of these patients who had recurrent oropharyngeal squamous cell carcinoma after chemoradiotherapy Results: The three-year actuarial survival rates for 75 patients by disease stage were as follows: stage II, 100 per cent; stage III, 71.1 per cent; stage IV, 51.7 per cent and overall, 58.2 per cent. The mean time of detection of recurrence was 6.2 months. The total salvage rates of recurrence were 21 per cent. The one and three-year tumour-free actuarial survival rates of those patients who received salvage treatment were 83 and 33 per cent.
  
  
  CONCLUSIONS
  Surgical salvage was only feasible for early recurrent tumour. Close follow-up surveillance of early recurrence is essential after primary treatment of patients with chemoradiotherapy.
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences,Kyushu University,Fukuoka,Japan.
authors.forename: R
authors.initials: R
authors.lastname: Yasumatsu
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences,Kyushu University,Fukuoka,Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nakashima
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences,Kyushu University,Fukuoka,Japan.
authors.forename: S
authors.initials: S
authors.lastname: Komune
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000628:therapy; D059248:Chemoradiotherapy / Q000401:mortality*; D018572:Disease-Free Survival; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D007564:Japan; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D009367:Neoplasm Staging / Q000401:mortality; D009959:Oropharyngeal Neoplasms / Q000401:mortality* / Q000628:therapy; D016879:Salvage Therapy / Q000401:mortality*; D015996:Survival Rate; D016896:Treatment Outcome
keywords: Salvage Treatment