title: Is gentamicin-impregnated collagen sponge to be recommended in pilonidal sinus patient treated with marsupialization? A prospective randomized study.
abstract: BACKGROUND
  The ideal treatment method for pilonidal sinus has always been a matter of debate. Although primary closure or various flap applications offer shorter wound healing times, their infection rates are very high. Secondary recovery involves long recovery period. The aim of this study is to investigate the effects of gentamicin-impregnated collagen sponge on wound healing and infection in patients undergoing marsupialization.
  
  
  METHODS
  Fifty patients were included in the study. Twenty-five patients in control group (Group 1) underwent excision and marsupialization. Gentamicin-impregnated collagen sponge was used postoperatively in twentyfive patients in group 2. Three-dimensional wound measurements were made on the 0.7 and 15th days and recorded.
  
  
  RESULTS
  No significant difference was observed between the groups in terms of development of hemorrhage and infection. Excessive granulation was detected in five patients (two in group 1 and three in group 2). There was no significant difference between the groups with respect to this criterion. Full recovery times were 29.6 and 28.2 days respectively. No statistically significant difference was observed between the groups (p = 0.571). None of the patients developed recurrence at the end of the follow-up period of 6-30 months.
  
  
  CONCLUSIONS
  In accordance with the results obtained in this randomized and controlled study, no significant difference was observed between gentamicin-impregnated collagen sponge group and control group with respect to development of infection, hemorrhage and wound healing times. Therefore, we do not recommend the use of gentamicin-impregnated collagen sponge after marsupialization.
  
  
  BACKGROUND
  Gentamicin-impregnated collagen sponge, Marsupialization, Pilonidal sinus.
authors.forename: Gokhan Selcuk
authors.initials: GS
authors.lastname: Ozbalci
authors.forename: Salih
authors.initials: S
authors.lastname: Tuncal
authors.forename: Kenan
authors.initials: K
authors.lastname: Bayraktar
authors.forename: Volkan
authors.initials: V
authors.lastname: Tasova
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ali Akkus
mesh_terms: D000279:Administration, Cutaneous; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D003094:Collagen; D005260:Female; D005500:Follow-Up Studies; D005839:Gentamicins / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D010864:Pilonidal Sinus / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D011446:Prospective Studies; D015503:Surgical Sponges; D013530:Surgical Wound Infection / Q000517:prevention & control*; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D003094:Collagen