title: Markers of myocardial damage in children of the first year of life with congenital heart disease in the early period after surgery with cardioplegic anoxia.
abstract: We measured the level of cardiac markers (high-sensitivity troponin T and MB fraction of creatine kinase) in children of the first year of life with congenital heart disease in the perioperative period. After cardiac surgery, plasma levels of the above markers exceed the reference limits in the examined children. The diagnosis of myocardial ischemia using biochemical markers in the postoperative period is possible only by dynamic monitoring of the cardiac marker level. The preoperative concentration of high-sensitivity troponin T in children of the first year of life with congenital heart disease can be regarded as a predictor of postoperative complications.
authors.affiliation: Department of Clinical Laboratory Diagnostics, Moscow, Russia, elenakozar@mail.ru.
authors.forename: E F
authors.initials: EF
authors.lastname: Kozar
authors.forename: M G
authors.initials: MG
authors.lastname: Plyushch
authors.forename: A E
authors.initials: AE
authors.lastname: Popov
authors.forename: O I
authors.initials: OI
authors.lastname: Kulaga
authors.forename: R R
authors.initials: RR
authors.lastname: Movsesyan
authors.forename: N N
authors.initials: NN
authors.lastname: Samsonova
authors.forename: L A
authors.initials: LA
authors.lastname: Bokeriya
mesh_terms: D019540:Area Under Curve; D015415:Biomarkers / Q000097:blood*; D052279:Creatine Kinase, MB Form / Q000097:blood; D006324:Heart Arrest, Induced / Q000009:adverse effects*; D006330:Heart Defects, Congenital / Q000097:blood / Q000150:complications / Q000601:surgery*; D006801:Humans; D000860:Hypoxia / Q000209:etiology / Q000473:pathology*; D007223:Infant; D017202:Myocardial Ischemia / Q000175:diagnosis* / Q000209:etiology; D012372:ROC Curve; D020107:Troponin T / Q000097:blood
chemical_list: D015415:Biomarkers; D020107:Troponin T; D052279:Creatine Kinase, MB Form