title: Potential sonodynamic anticancer activities of artemether and liposome-encapsulated artemether.
abstract: The potential application of artemether as a novel sonosensitizer for sonodynamic therapy (SDT) was explored and illustrated for the first time. In addition, liposome-encapsulated artemether exhibited significantly enhanced sonodynamic anticancer activity. Our findings indicated that artemisinin derivatives may serve as a new kind of sonosensitizer for SDT.
authors.affiliation: College of Chemistry, State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou 350116, China. jdhuang@fzu.edu.cn.
authors.forename: Hai-Jun
authors.initials: HJ
authors.lastname: Chen
authors.forename: Xiu-Rong
authors.initials: XR
authors.lastname: Huang
authors.forename: Xiao-Bin
authors.initials: XB
authors.lastname: Zhou
authors.forename: Bi-Yuan
authors.initials: BY
authors.lastname: Zheng
authors.forename: Jian-Dong
authors.initials: JD
authors.lastname: Huang
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology*; D000077549:Artemether; D037621:Artemisinins / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004354:Drug Screening Assays, Antitumor; D056945:Hep G2 Cells; D006801:Humans; D008081:Liposomes; D061986:MCF-7 Cells; D008968:Molecular Conformation; D017382:Reactive Oxygen Species / Q000378:metabolism; D013329:Structure-Activity Relationship; D014464:Ultrasonic Therapy
chemical_list: D000970:Antineoplastic Agents; D037621:Artemisinins; D008081:Liposomes; D017382:Reactive Oxygen Species; D000077549:Artemether