title: Angiotensin II receptor antagonists (AT1-blockers, ARBs, sartans): similarities and differences.
abstract: A survey is presented of the registered non-peptidergic angiotensin II receptor antagonists (AT1blockers, ARBs, sartans) and their general properties and similarities. Accordingly, their receptor profile, pharmacokinetic and therapeutic applications are discussed. In addition, attention is paid to the individual characteristics of the AT1blockers now available. A few components of this category offer additional potentially beneficial properties, owing to their pharmacological or metabolic characteristics. Such additional properties are critically discussed for eprosartan, losartan, telmisartan and valsartan.
authors.forename: P A
authors.initials: PA
authors.lastname: van Zwieten
keywords: AT1 receptors; angiotensin II receptor antagonists; insulin sensitisation; renin-angiotensin system