title: Trends in surgical site infections following orthopaedic surgery.
abstract: OBJECTIVE
  This review presents an update on recent findings relating to the prevention, control and epidemiology of infections following orthopaedic surgery.
  
  
  RESULTS
  Trends in population rates and characteristics of patients undergoing hip and knee replacement surgery, coupled with the reported excess infection risk in obese patients, emphasize the current and future impact of increasing population obesity on healthcare delivery.
  
  
  CONCLUSIONS
  Prevention of orthopaedic infection is dependent on elimination or optimal management of documented risk factors. Guidelines and quality standards play a key role in translating this evidence base into a framework of practices for the prevention of surgical site infections. Increasing levels of orthopaedic infection due to Enterobacteriaceae, coupled with an increasingly obese surgical population may necessitate a reassessment of antimicrobial prophylaxis strategies.
authors.affiliation: Department of Healthcare-Associated Infection and Antimicrobial Resistance, Public Health England, London, UK.
authors.forename: Theresa
authors.initials: T
authors.lastname: Lamagni
authors.forename: Suzanne
authors.initials: S
authors.lastname: Elgohari
authors.forename: Pauline
authors.initials: P
authors.lastname: Harrington
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000379:methods*; D006801:Humans; D017053:Infection Control / Q000379:methods; D009765:Obesity / Q000150:complications; D019637:Orthopedic Procedures / Q000009:adverse effects*; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents