title: Urinary tract symptoms and erectile function in patients at risk of prostate cancer.
abstract: OBJECTIVE
  We estimate that more tan 63000 prostate biopsies are performed in our country each year. There are no functional status data of those patients and if there is a relationship between biopsy result and functional status. In order to solve that question we have performed this study.
  
  
  METHODS
  1,128 prostate biopsies were included. Patients fill in the IPSS, IIEF-5 and ICIQ-SF questionnaires before the prostate biopsy was performed. A prospective data collection of clinical, pathological and questionnaires results was done. A descriptive analysis was carried out. IPSS and IIEF-5 results were categorized. Results were compared depending on the biopsy result. In the subgroup of patients with prostate cancer, questionnaires results were stratify according to the clinical risk group.
  
  
  RESULTS
  The mean age of the sample was 65. Prostate cancer detection rate was 32,71%, 52,2% of the sample had mild lower urinary tract symptoms (LUTS) and 13,4% had severe LUTS at the time of the biopsy. Regarding the impact of LUTS on quality of life (QOL), only 12,6% showed a perfect QOL. More than 50 percent of patients suffered from some degree of erectile dysfunction at the time of the biopsy. According to ICIQ-SF, 24% of the sample experienced some kind of urinary incontinence, although it is true that most of them classified it as small amount. Patients with a positive biopsy had a lower IPSS and IIEF-5 average score. There were no differences in the prostate cancer detection rate stratified by the severity of LUTS.
  
  
  CONCLUSIONS
  Patients undergoing prostate biopsy have, with a high probability, LUTS. Approximately 50% suffer from some degree of erectile dysfunction and 24% had some kind of urinary leakage.
authors.affiliation: Servicio de Urología, Fundación Instituto Valenciano de Urología (FIVO), Valencia, España. Electronic address: ramirezbackhaus@yahoo.es.
authors.forename: M
authors.initials: M
authors.lastname: Ramírez-Backhaus
authors.affiliation: Servicio de Urología, Fundación Instituto Valenciano de Urología (FIVO), Valencia, España.
authors.forename: J
authors.initials: J
authors.lastname: González-Tampán
authors.affiliation: Departamento de Estadística e Investigación Operativa, Facultad de Matemáticas, Universidad de Almería, Almería, España.
authors.forename: I M
authors.initials: IM
authors.lastname: Ortiz-Rodríguez
authors.affiliation: Servicio de Urología, Fundación Instituto Valenciano de Urología (FIVO), Valencia, España.
authors.forename: Á
authors.initials: Á
authors.lastname: Gómez-Ferrer
authors.affiliation: Servicio de Urología, Fundación Instituto Valenciano de Urología (FIVO), Valencia, España.
authors.forename: J
authors.initials: J
authors.lastname: Rubio-Briones
authors.affiliation: Servicio de Urología, Fundación Instituto Valenciano de Urología (FIVO), Valencia, España.
authors.forename: A
authors.initials: A
authors.lastname: Collado-Serra
authors.affiliation: Servicio de Anatomía Patológica, FIVO, Valencia, España.
authors.forename: A
authors.initials: A
authors.lastname: Calatrava
authors.affiliation: Departamento de Estadística e Investigación Operativa, Facultad de Matemáticas, Universidad de Almería, Almería, España.
authors.forename: C
authors.initials: C
authors.lastname: Rodríguez-Torreblanca
authors.affiliation: Servicio de Urología, Fundación Instituto Valenciano de Urología (FIVO), Valencia, España.
authors.forename: E
authors.initials: E
authors.lastname: Solsona-Narbón
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000453:epidemiology* / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D000066491:Clinical Decision-Making; D015897:Comorbidity; D007172:Erectile Dysfunction / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000150:complications / Q000453:epidemiology* / Q000473:pathology; D012306:Risk; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D014549:Urinary Incontinence / Q000453:epidemiology / Q000209:etiology
keywords: Biopsia de próstata; Cáncer de próstata; Disfunción eréctil; Erectile dysfunction; Lower urinary tract symptoms; Prostate cancer; Prostatic biopsy; Síntomas del tracto urinario inferior