title: How to Valorize Biodiversity? Let's Go Hashing, Extracting, Filtering, Mining, Fishing.
abstract: Nature was and still is a prolific source of inspiration in pharmacy, cosmetics, and agro-food industries for the discovery of bioactive products. Informatics is now present in most human activities. Research in natural products is no exception. In silico tools may help in numerous cases when studying natural substances: in pharmacognosy, to store and structure the large and increasing number of data, and to facilitate or accelerate the analysis of natural products in regards to traditional uses of natural resources; in drug discovery, to rationally design libraries for screening natural compound mimetics and identification of biological activities for natural products. Here we review different aspects of in silico approaches applied to the research and development of bioactive substances and give examples of using nature-inspiring power and ultimately valorize biodiversity.
authors.affiliation: Greenpharma S. A. S., Orléans, France.
authors.forename: Quoc Tuan
authors.initials: QT
authors.lastname: Do
authors.affiliation: Facultad de Química, Departamento de Farmacia, Universidad Nacional Autónoma de México, Mexico City, Mexico.
authors.forename: José L
authors.initials: JL
authors.lastname: Medina-Franco
authors.affiliation: Department of Pharmacy, Benemérita Universidad Autónoma de Puebla, Puebla, México.
authors.forename: Thomas
authors.initials: T
authors.lastname: Scior
authors.affiliation: Greenpharma S. A. S., Orléans, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Bernard
mesh_terms: D044822:Biodiversity; D001688:Biological Products; D003198:Computer Simulation; D057225:Data Mining; D055808:Drug Discovery
chemical_list: D001688:Biological Products