title: Nanostructure changes in the intervertebral discs after experimental laser irradiation.
abstract: Laser-induced changes in the intervertebral discs were studied by the method of atomic force microscopy. Alteration of the proximal caudal intervertebral discs was modeled in rats: puncture and exposure to diode laser (2, 3, or 5 W) in constant or pulse regimens or only puncture (control). Nanostructure of disc surface was estimated by surface skewness, root mean square and average roughness, and coefficient of kurtosis. Maximum positive effect and signs of regenerative changes in the surface microstructure of the intervertebral discs were found after exposure to laser (2-3 W) in constant or pulse regimens.
authors.affiliation: Research Center of Reconstructive and Restorative Surgery, Siberian Division of the Russian Academy of Medical Sciences, Irkutsk, Russia, byval75vadim@yandex.ru.
authors.forename: V A
authors.initials: VA
authors.lastname: Byval'tsev
authors.forename: S Yu
authors.initials: SY
authors.lastname: Panasenkov
authors.forename: E G
authors.initials: EG
authors.lastname: Belykh
authors.forename: N A
authors.initials: NA
authors.lastname: Ivanov
authors.forename: P Yu
authors.initials: PY
authors.lastname: Tsyganov
authors.forename: S B
authors.initials: SB
authors.lastname: Nikiforov
authors.forename: V A
authors.initials: VA
authors.lastname: Sorokovikov
authors.forename: E G
authors.initials: EG
authors.lastname: Grigor'ev
authors.forename: S I
authors.initials: SI
authors.lastname: Kolesnikov
mesh_terms: D000818:Animals; D007403:Intervertebral Disc / Q000293:injuries / Q000528:radiation effects* / Q000648:ultrastructure*; D007834:Lasers; D018625:Microscopy, Atomic Force; D051381:Rats; D017208:Rats, Wistar; D014945:Wound Healing / Q000502:physiology* / Q000528:radiation effects