title: [A prolonged capillary refill is predictor of low central venous oxygen saturation].
abstract: BACKGROUND
  Educational programs in pediatric life support endorse a capillary refill time>2 s as an indicator of shock. In the emergency room, a barrier to the implementation of an early goal directed therapy, aiming at central venous oxygen saturation (ScvO2)≥70% is the insertion of central venous catheter (CVC).
  
  
  OBJECTIVE
  To establish the predictive value of capillary refill time>2 s to detect ScvO2<70% in children admitted to Intensive Care Units.
  
  
  METHODS
  Prospective study. We included 48 children admitted in the first 24 hours in ICU with superior vena cava CVC. Simultaneously, we measured ScvO2 and capillary refill time in the heel of upper extremity or toe.
  
  
  RESULTS
  There were 75 paired measurements ScvO2 (75,9±8,4%) and capillary refill capillary (1,9±1,0 s). We found an inverse correlation between capillary refill time and ScvO2 (r-0,58). The ROC curve analysis revealed an excellent ability for the capillary fill time>2 s to predict ScvO2<70% (AUC 0,94) (95% CI 0,87-0,98).
  
  
  CONCLUSIONS
  A prolonged capillary refill time>2 s, is a predictor of ScvO2<70% in children admitted to ICU, which supports the current recommendations. This finding may be relevant in emergency units where the use of CVC is limited and ScvO2 is not available.
authors.forename: R
authors.initials: R
authors.lastname: Bustos
authors.forename: O
authors.initials: O
authors.lastname: Padilla
mesh_terms: D000293:Adolescent; D002196:Capillaries / Q000502:physiology; D002405:Catheterization, Central Venous / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007362:Intensive Care Units; D008297:Male; D010100:Oxygen / Q000097:blood*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012772:Shock, Septic / Q000097:blood*; D013997:Time Factors; D014683:Vena Cava, Superior
chemical_list: D010100:Oxygen