title: Phasic and tonic pain differentially impact the interruptive function of pain.
abstract: The interruptive effect of painful experimental stimulation on cognitive processes is a well-known phenomenon. This study investigated the influence of pain duration on the negative effects of pain on cognition. Thirty-four healthy volunteers performed a rapid serial visual presentation task (RSVP) in which subjects had to detect (visual detection task) and count the occurrence of a target letter (working memory task) in two separate sessions while being stimulated on the left volar forearm with either short (2 sec) or long (18 sec) painful heat stimuli of equal subjective intensity. The results show that subjects performed significantly worse in the long pain session as indexed by decreased detection and counting performance. Interestingly, this effect on performance was also observed during control trials of the long pain session in which participants did not receive any painful stimulation. Moreover, subjects expected long painful stimulation to have a greater impact on their performance and individual expectation correlated with working memory performance. These findings suggest that not only the length of painful stimulation but also its expected ability to impair cognitive functioning might influence the interruptive function of pain. The exact relevance of expectation for the detrimental effects of pain on cognitive processes needs to be explored in more detail in future studies.
authors.affiliation: Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
authors.forename: Christopher
authors.initials: C
authors.lastname: Sinke
authors.affiliation: Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Neurology, Essen University Hospital, Essen, Germany.
authors.forename: Katharina
authors.initials: K
authors.lastname: Schmidt
authors.affiliation: Department of Neurology, Essen University Hospital, Essen, Germany.
authors.forename: Katarina
authors.initials: K
authors.lastname: Forkmann
authors.affiliation: Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Neurology, Essen University Hospital, Essen, Germany.
authors.forename: Ulrike
authors.initials: U
authors.lastname: Bingel
mesh_terms: D000293:Adolescent; D000328:Adult; D003071:Cognition / Q000502:physiology; D005260:Female; D064368:Healthy Volunteers; D006358:Hot Temperature; D006801:Humans; D008297:Male; D010146:Pain / Q000145:classification / Q000503:physiopathology*; D010147:Pain Measurement; D011795:Surveys and Questionnaires; D055815:Young Adult