title: Whole eye segment imaging and measurement with dual-channel spectral-domain OCT.
abstract: OBJECTIVE
  To image and measure whole eye segments using dual-channel spectral-domain optical coherence tomography (SD-OCT) and to compare the results with those from the IOLMaster (Carl Zeiss Meditec, Dublin, CA).
  
  
  METHODS
  Twenty eyes of 20 volunteers were recruited. Ocular dimensions, including cornea thickness, anterior chamber depth (ACD), lens thickness, anterior lens surface curvature, and axial length (AL), were calculated. The reproducibility of SD-OCT measurements, statistical significance of inter-instrument difference, correlation, and agreement were evaluated.
  
  
  RESULTS
  No significant differences were found between independent SD-OCT measurements (P > .05). The ACD and AL measured with IOLMaster were significantly shorter than those from SD-OCT (P < .001). There were high correlations and agreements in ACD (r = 0.994; 95% limits of agreement [LOA], 0.131-0.223 mm) and AL (r = 0.998; 95% LOA, 0.678-0.853 mm) between the two methods.
  
  
  CONCLUSIONS
  Dual-channel SD-OCT was demonstrated to have good repeatability in imaging and measuring whole eye segments. The results had high correlations and agreements with those from the IOLMaster.
authors.forename: Shanhui
authors.initials: S
authors.lastname: Fan
authors.forename: Yong
authors.initials: Y
authors.lastname: Sun
authors.forename: Xuan
authors.initials: X
authors.lastname: Yang
authors.forename: Cuixia
authors.initials: C
authors.lastname: Dai
authors.forename: Qiushi
authors.initials: Q
authors.lastname: Ren
authors.forename: Haihua
authors.initials: H
authors.lastname: Zheng
authors.forename: Chuanqing
authors.initials: C
authors.lastname: Zhou
mesh_terms: D000328:Adult; D000869:Anterior Eye Segment / Q000033:anatomy & histology*; D058452:Axial Length, Eye / Q000033:anatomy & histology*; D001699:Biometry; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D007368:Interferometry / Q000379:methods; D008027:Light; D008297:Male; D009929:Organ Size; D057972:Posterior Eye Segment / Q000033:anatomy & histology*; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence; D055815:Young Adult