title: Acceptability and Efficacy of Commercial Oral Preparation of Midazolam for brief Painful Procedure: A Randomized Double Blind Clinical Trial.
abstract: OBJECTIVE
  To compare the acceptability and efficacy of orally administered commercially available midazolam syrup and injection midazolam mixed in honey for performing venepuncture.
  
  
  METHODS
  This double blind randomized controlled trial enrolled 40 anxious and healthy 2 to 6 years olds. All subjects received either syrup midazolam or injection midazolam mixed in honey (0.5 mg/kg) per orally, prior to venepuncture as per their group assignment. Primary outcome measures in this trial was acceptability of midazolam. Secondary outcome measures included sedation depth, success of venepuncture, observer and parental satisfaction and parental perception of child's pain.
  
  
  RESULTS
  Although the acceptability of syrup midazolam (95%) was higher than injection midazolam (80%), there was no significant difference among two groups with respect to any primary or secondary outcome (p > 0.05).
  
  
  CONCLUSIONS
  Syrup midazolam can serve as a suitable alternative to injection midazolam; thus, eliminating the procedural steps of mixing injection midazolam with any vehicle. How to cite this article: Srivastava B, Mittal N, Mittal P. Acceptability and Efficacy of Commercial Oral Preparation of Midazolam for brief Painful Procedure: A Randomized Double Blind Clinical Trial. Int J Clin Pediatr Dent 2014;7(3):153-156.
authors.affiliation: Professor and Head, Department of Pedodontics and Preventive Dentistry, Santosh Dental College and Hospital, Ghaziabad, Uttar Pradesh, India.
authors.forename: Binita
authors.initials: B
authors.lastname: Srivastava
authors.affiliation: Assistant Professor, Department of Pediatric and Preventive Dentistry, Santosh Dental College and Hospital, Ghaziabad, Uttar Pradesh, India.
authors.forename: Neeti
authors.initials: N
authors.lastname: Mittal
authors.affiliation: Senior Consultant, Department of Pediatrics, Private Practice, NCT-Delhi, India.
authors.forename: Parteek
authors.initials: P
authors.lastname: Mittal
keywords: Behavior management; Midazolam; Syrup.