title: [Association of the genenetic polymorphism of cytokines and their receptors with climate and geographic factors in human populations].
abstract: The variability of eight polymorphic variants of the IL4, IL4R, IL10, IL13, IL12A, and IL12RB2 genes encoding key cytokinesand their receptors in 57 world populations has been assessed. A correlation between the allele frequency distribution of the examined genes and climatic and geographic factors was observed.
authors.forename: A A
authors.initials: AA
authors.lastname: Cherednichenko
authors.forename: E A
authors.initials: EA
authors.lastname: Trifonova
authors.forename: K V
authors.initials: KV
authors.lastname: Vagaitseva
authors.forename: A V
authors.initials: AV
authors.lastname: Bocharova
authors.forename: V A
authors.initials: VA
authors.lastname: Stepanov
mesh_terms: D002980:Climate; D005787:Gene Frequency; D006801:Humans; D007378:Interleukins / Q000235:genetics*; D011110:Polymorphism, Genetic; D053707:Receptors, Interleukin-12 / Q000235:genetics*
chemical_list: C508439:IL12RB2 protein, human; D007378:Interleukins; D053707:Receptors, Interleukin-12