title: [Current Topics on Vitamin D. Influences of vitamin D on muscle cells and function].
abstract: Vitamin D deficiency is associated with sarcopenia, which is characterized by the decrease in muscle mass and the muscle weakness. Active form of vitamin D binds to nuclear or non-nuclear vitamin D receptor (VDR) and regulates the proliferation and differentiation of myoblasts through its genomic or non-genomic actions. Clinical evidence showed the beneficial effects of vitamin D treatment on muscle mass and function in older people. Recent studies suggest that vitamin D is associated with the preservation of muscle function related to the interactions between bone and muscle.
authors.affiliation: Department of Physiology and Regenerative Medicine, Kinki University Faculty of Medicine, Japan.
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Tamura
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kaji
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D006801:Humans; D018908:Muscle Weakness / Q000188:drug therapy / Q000378:metabolism; D018482:Muscle, Skeletal / Q000378:metabolism*; D018167:Receptors, Calcitriol / Q000378:metabolism*; D014807:Vitamin D / Q000378:metabolism*
chemical_list: D018167:Receptors, Calcitriol; D014807:Vitamin D