title: Numerical evaluation of blood viscosity affecting pulse wave propagation in a fluid-structure interaction model.
abstract: High blood viscosity often causes cardiovascular diseases, such as hypertension, atherosclerosis and thrombosis. It is proven that blood viscosity plays an important role in cardiovascular functions. In this paper, pulse wave characteristics with normal and high blood viscosities are presented in detail to evaluate how blood viscosity affects pulse wave propagation. A fluid-structure interaction is employed to solve for pulse wave characteristics. The results show that increased blood viscosity does not change the time delay of wave propagation. However, high viscosity reduces the velocity amplitude, while it enhances the pressure level. This study provides physical insight for evaluating blood viscosity leading potentially to pulse wave changes.
authors.forename: Fan
authors.initials: F
authors.lastname: He
authors.forename: Lu
authors.initials: L
authors.lastname: Hua
authors.forename: Li-jian
authors.initials: LJ
authors.lastname: Gao
mesh_terms: D062186:Arterial Pressure / Q000502:physiology*; D001158:Arteries / Q000502:physiology*; D001783:Blood Flow Velocity / Q000502:physiology; D001809:Blood Viscosity / Q000502:physiology*; D003198:Computer Simulation; D006801:Humans; D008955:Models, Cardiovascular; D009716:Numerical Analysis, Computer-Assisted; D063177:Pulse Wave Analysis / Q000379:methods*; D012212:Rheology; D033081:Shear Strength / Q000502:physiology