title: 2013 ASCO/CAP updated guidelines for human epidermal growth factor receptor 2 testing: Impact on routine practice.
abstract: The release of the new ASCO/CAP guideline recommendations for human epidermal growth factor receptor 2 testing has led to clearer descriptive definitions for immunohistochemistry categories. As soon as we started to use them we realized that an increase in the number of ISH test was occurring. Herein we report our lab data obtained by comparing the semester after the release of the new guidelines with the same semester of the previous year. The impact on routine work practice is highlighted.
authors.affiliation: Institute of Pathology, Catholic University of Sacred Heart, Rome, Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Pennacchia
authors.affiliation: Institute of Pathology, Catholic University of Sacred Heart, Rome, Italy.
authors.forename: Arnaldo
authors.initials: A
authors.lastname: Carbone
authors.affiliation: Institute of Pathology, Catholic University of Sacred Heart, Rome, Italy.
authors.forename: Arcangelo
authors.initials: A
authors.lastname: Di Cerbo
authors.affiliation: Institute of Pathology, Catholic University of Sacred Heart, Rome, Italy.
authors.forename: Fabio Maria
authors.initials: FM
authors.lastname: Vecchio
authors.affiliation: Institute of Pathology, Catholic University of Sacred Heart, Rome, Italy. Electronic address: vincenzo.arena@rm.unicatt.it.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Arena
mesh_terms: D001943:Breast Neoplasms / Q000139:chemically induced*; D055088:Early Detection of Cancer / Q000592:standards / Q000639:trends*; D005260:Female; D006801:Humans; D009363:Neoplasm Proteins / Q000032:analysis*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000592:standards / Q000639:trends*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000032:analysis*
chemical_list: D009363:Neoplasm Proteins; D018719:Erb-b2 Receptor Tyrosine Kinases; C508053:ERBB2 protein, human
keywords: ASCO/CAP; Guidelines; HER2