title: Incidence and mortality of laryngeal cancer in China, 2011.
abstract: OBJECTIVE
  Laryngeal cancer is the common cancer of the upper aerodigestive tract. We aimed to use the national cancer registration data in 2011 to estimate the incidence and mortality of laryngeal cancer within China.
  
  
  METHODS
  Comparable, high-quality data from 177 population-based cancer registries were qualified for analysis. The pooled data were stratified by area, sex and age group. National new cases and deaths of laryngeal cancer were estimated using age-specific rates and national population in 2010. All incidence and death rates were age-standardized to the 2000 Chinese standard population and Segi's population, which were expressed per 100,000 populations.
  
  
  RESULTS
  All 177 cancer registries covered a total of 175,310,169 population (98,341,507 in urban and 76,968,662 in rural areas), accounting for 13.01% of the national population. The data quality indicators of proportion of morphological verification (MV%), percentage of cancer cases identified with death certification only (DCO%) and mortality to incidence ratio (M/I) were 77.98%, 2.62% and 0.55, respectively. Estimated 20,875 new cases of laryngeal cancer were diagnosed and 11,488 deaths from laryngeal cancer occurred in China in 2011. The crude incidence rate of laryngeal cancer was 1.55/100,000 (2.69/100,000 in males and 0.35/100,000 in females). Age-standardized incidence rates by Chinese standard population (ASIRC) and by world standard population (ASIRW) were 1.13/100,000 and 1.14/100,000, respectively. Laryngeal cancer is much rarer in females than in males. The incidence rate was higher in urban areas than that in rural areas. The crude mortality rate of laryngeal cancer was 0.85/100,000 (1.42/100,000 in males and 0.25/100,000 in females). Age-standardized mortality rates by Chinese standard population (ASMRC) and by world standard population (ASMRW) were both 0.61/100,000. The mortality rate in males was much higher than that in females. There was no definite difference in mortality rates of laryngeal cancer between urban and rural areas.
  
  
  CONCLUSIONS
  Larynx is a specialized area and cancer of larynx significantly affects the quality of life for the patients. Comprehensive measures should be carried out to prevent the ascent of laryngeal cancer.
authors.affiliation: 1 Zhejiang Provincial Office for Cancer Prevention and Control, Zhejiang Cancer Center, Hangzhou 310022, China ; 2 National Office for Cancer Prevention and Control, National Cancer Center, Beijing 100021, China.
authors.forename: Lingbin
authors.initials: L
authors.lastname: Du
authors.affiliation: 1 Zhejiang Provincial Office for Cancer Prevention and Control, Zhejiang Cancer Center, Hangzhou 310022, China ; 2 National Office for Cancer Prevention and Control, National Cancer Center, Beijing 100021, China.
authors.forename: Huizhang
authors.initials: H
authors.lastname: Li
authors.affiliation: 1 Zhejiang Provincial Office for Cancer Prevention and Control, Zhejiang Cancer Center, Hangzhou 310022, China ; 2 National Office for Cancer Prevention and Control, National Cancer Center, Beijing 100021, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Zhu
authors.affiliation: 1 Zhejiang Provincial Office for Cancer Prevention and Control, Zhejiang Cancer Center, Hangzhou 310022, China ; 2 National Office for Cancer Prevention and Control, National Cancer Center, Beijing 100021, China.
authors.forename: Rongshou
authors.initials: R
authors.lastname: Zheng
authors.affiliation: 1 Zhejiang Provincial Office for Cancer Prevention and Control, Zhejiang Cancer Center, Hangzhou 310022, China ; 2 National Office for Cancer Prevention and Control, National Cancer Center, Beijing 100021, China.
authors.forename: Siwei
authors.initials: S
authors.lastname: Zhang
authors.affiliation: 1 Zhejiang Provincial Office for Cancer Prevention and Control, Zhejiang Cancer Center, Hangzhou 310022, China ; 2 National Office for Cancer Prevention and Control, National Cancer Center, Beijing 100021, China.
authors.forename: Wanqing
authors.initials: W
authors.lastname: Chen
keywords: China; Laryngeal cancer; cancer registry; epidemiology; incidence; mortality