title: Squamous cell carcinoma and pilonidal cyst disease.
abstract: OBJECTIVE
  Squamous cell carcinoma developed on a chronic pilonidal cyst.
  
  
  METHODS
  Authors describe the case of a squamous cell carcinoma developed on a chronic pilonidal cyst in a 63- years-old patient with a 43 years history of recurrent pilonidal sinus disease.
  
  
  RESULTS
  The patient underwent incisional biopsy, staging with total body CT and, finally, radical surgery. After 30 months there were no evidence of recurrence.
  
  
  CONCLUSIONS
  Pilonidal sinus disease is a common disease that affects especially male subjects, obese and with excess of body hair. The complications that arise most frequently are cellulitis, abscess formation and developments of recurrences. Malignant transformation appears rather rare and is reported in the literature with a percentage that goes from 0.02% to 0.1%.
  
  
  CONCLUSIONS
  Authors recommend accurate inspection of the pilonidal area in all chronic and longstanding inflammatory lesions and possibly practice incisional biopsies to exclude malignant degeneration.
authors.forename: Francesco
authors.initials: F
authors.lastname: Esposito
authors.forename: Mario
authors.initials: M
authors.lastname: Lauro
authors.forename: Lucio Pasquale
authors.initials: LP
authors.lastname: Tirone
authors.forename: Rosa Maria
authors.initials: RM
authors.lastname: Festa
authors.forename: Gaia
authors.initials: G
authors.lastname: Peluso
authors.forename: Giada
authors.initials: G
authors.lastname: Mazzoni
authors.forename: Marco
authors.initials: M
authors.lastname: Scognamiglio
authors.forename: Simona
authors.initials: S
authors.lastname: Grimaldi
authors.forename: Antonio
authors.initials: A
authors.lastname: Fresini
mesh_terms: D000038:Abscess / Q000209:etiology; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000601:surgery*; D017577:Cutaneous Fistula / Q000209:etiology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D010864:Pilonidal Sinus / Q000150:complications* / Q000601:surgery; D012008:Recurrence; D012878:Skin Neoplasms / Q000209:etiology / Q000601:surgery*; D013524:Surgical Flaps