title: Mild cognitive impairment definitions: more evolution than revolution.
abstract: Early identification of those at higher risk of dementia may play a part in secondary prevention and has received great clinical and research interest. Mild cognitive impairment (MCI) is a construct originally proposed to identify those who fall between normal cognitive aging and dementia. Clinical and research utility and validity of MCI are hotly debated. New MCI criteria proposed include the recent construct of mild neurocognitive disorder in the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders, MCI criteria proposed by the National Institute on Aging-Alzheimer's Society and criteria elaborated by the International Working Group. This article aims to discuss whether these definitions provide clearer conceptualization of MCI and to highlight implications for research.
authors.affiliation: Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Eugene Yh
authors.initials: EY
authors.lastname: Tang
authors.forename: Carol
authors.initials: C
authors.lastname: Brayne
authors.forename: Emiliano
authors.initials: E
authors.lastname: Albanese
authors.forename: Blossom Cm
authors.initials: BC
authors.lastname: Stephan
mesh_terms: D000544:Alzheimer Disease / Q000150:complications; D060825:Cognitive Dysfunction / Q000175:diagnosis / Q000209:etiology; D039721:Diagnostic and Statistical Manual of Mental Disorders; D006801:Humans; D038622:Internationality; D009626:Terminology as Topic
keywords: Alzheimer's disease; biomarkers; criteria; dementia; diagnosis; mild cognitive impairment; prevention