title: West Nile virus infection in Ogbomoso: serological evidence.
abstract: A seroepidemiological study for West Nile virus was carried out in an urban and rural settlements in Ogbomoso for its IgM and IgG. Human sera was obtained and West Nile virus IgM and IgG was determined using Enzyme Linked Immunosorbent Assay technique. Out of 93 subjects tested, 19.4% and 12.9% were positive for IgG and IgM, respectively. Among the urban dwellers, 23.40% were positive for both IgG and IgM, while the rural dwellers had 15.22% for IgG and 2.17% for IgM. Test for pure antibody to West Nile virus revealed that 23.7% had the virus while 8.6% had antibodies that cross reacted for other flaviviruses. Results show that West Nile virus is circulating in Ogbomoso and its environ which might have accounted for malaria like infection in the region.
authors.affiliation: a Department of Pure and Applied Biology (Microbiology/Virology Unit) , Ladoke Akintola University of Technology , Ogbomoso , Nigeria.
authors.forename: Oladipo Elijah
authors.initials: OE
authors.lastname: Kolawole
authors.forename: Oloke Julius
authors.initials: OJ
authors.lastname: Kola
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D014901:West Nile Fever / Q000097:blood* / Q000453:epidemiology*; D014902:West Nile virus
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M
keywords: ELISA; West Nile; flaviviruses; immunoglobulin; ogbomoso