title: Asian genotypes of dengue virus 4 in Brazil.
abstract: Dengue virus, commonly transmitted by mosquitoes, causes a human disease of significant social impact and presents a serious public health problem in Brazil. This report describes the unusual emergence of DENV-4 in northern Brazil after a nearly 30-year-long absence. DENV-4 genotype I is of Asian origin and was identified in the serum of patients receiving treatment at a hospital serving the Salvador area (Brazilian state of Bahia). The identification of dengue virus serotypes through molecular and phylogenetic analysis is essential for predicting disease severity or fatal illness, principally in endemic countries such as Brazil.
authors.affiliation: Laboratory of Virology,Health Science Institute,Federal University of Bahia,Salvador,Bahia,Brazil.
authors.forename: A C O
authors.initials: AC
authors.lastname: Pinho
authors.affiliation: Laboratory of Virology,Health Science Institute,Federal University of Bahia,Salvador,Bahia,Brazil.
authors.forename: S I
authors.initials: SI
authors.lastname: Sardi
authors.affiliation: Federal University of Reconcavo of Bahia,Brazil.
authors.forename: F L
authors.initials: FL
authors.lastname: Paula
authors.affiliation: Laboratory of Virology,Health Science Institute,Federal University of Bahia,Salvador,Bahia,Brazil.
authors.forename: I B
authors.initials: IB
authors.lastname: Peixoto
authors.affiliation: Aliança Hospital,Salvador,Bahia,Brazil.
authors.forename: C J
authors.initials: CJ
authors.lastname: Brandão
authors.affiliation: Institute of Biology,Federal University of Bahia,Salvador,Bahia,Brazil.
authors.forename: F M C
authors.initials: FM
authors.lastname: Fernandez
authors.affiliation: Laboratory of Virology,Health Science Institute,Federal University of Bahia,Salvador,Bahia,Brazil.
authors.forename: G S
authors.initials: GS
authors.lastname: Campos
mesh_terms: D001938:Brazil / Q000453:epidemiology; D003715:Dengue / Q000453:epidemiology / Q000821:virology*; D003716:Dengue Virus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D005838:Genotype; D006801:Humans; D017720:Molecular Epidemiology
keywords: Asian lines; Brazil; DENV-4