title: Copper-catalyzed skeletal rearrangements of O-propargylic oximes via cleavage of a carbon-oxygen bond.
abstract: In this account, we describe recent developments in copper-catalyzed skeletal 2,3-rearrangement reactions of O-propargylic oximes to form four-membered cyclic nitrones, pyridine N-oxides, and amidodienes via N-allenylnitrone intermediates. The sequence of events leading up to our encounter with O-propargylic oximes is also presented.
authors.affiliation: Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University, 6-3 Aramaki Aza Aoba, Aoba-ku, Sendai, 980-8578, Japan. itaru-n@m.tohoku.ac.jp.
authors.forename: Itaru
authors.initials: I
authors.lastname: Nakamura
authors.forename: Masahiro
authors.initials: M
authors.lastname: Terada
keywords: alkynes; cascade reactions; copper; heterocycles; rearrangement