title: An efficient method for the preparation of styrene derivatives via Rh(III)-catalyzed direct C-H vinylation.
abstract: The development of a method for the Rh(III)-catalyzed direct vinylation of an aromatic C-H bond to give functionalized styrenes in good yield, using vinyl acetate as a convenient and inexpensive vinyl source, is reported. High functional group tolerance is demonstrated for electronically distinct arenes as well as different directing groups. Mechanistic investigation resulted in the characterization of a novel rhodium-metallacycle, which represents the first X-ray structure of a [1,2]-Rh(III)-alkenyl addition adduct.
authors.affiliation: Department of Chemistry, Yale University , 225 Prospect Street, New Haven, Connecticut 06520-8107, United States.
authors.forename: Kate D
authors.initials: KD
authors.lastname: Otley
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Ellman
mesh_terms: D002384:Catalysis; D006860:Hydrogen Bonding; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*; D013343:Styrenes / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D013343:Styrenes; D014753:Vinyl Compounds; D012238:Rhodium; C011566:vinyl acetate