title: The determinants of spread of Ebola virus disease - an evidence from the past outbreak experiences.
abstract: The paper summarizes available evidence regarding the determinants of spread of Ebola virus disease, including health care and community related risk factors. It was observed that the level of uncertainty for the estimations is relatively high which may hinder to make some predictions for the future evolution of EVD outbreak. The natural history of EVD has shown that the disease may pose a problem to developed countries and may present a thread to individuals. Although observed modes of transmission mainly include direct contact and contaminated staff, high case fatality ratio and frequent contacts among individuals in developed countries are among determinants which may lead to the development of the EVD outbreak.
authors.affiliation: Chair of Epidemiology and Preventive Medicine, Department of Epidemiology, Jagiellonian University Medical College, Krakow, Poland. aleksander.galas@uj.edu.pl or mygalas@cyf-kr.edu.pl.
authors.forename: Aleksander
authors.initials: A
authors.lastname: Gałas
mesh_terms: D000354:Africa, Western / Q000453:epidemiology; D003140:Communicable Disease Control / Q000379:methods; D004196:Disease Outbreaks / Q000517:prevention & control*; D018562:Disease Transmission, Infectious / Q000517:prevention & control; D029043:Ebolavirus / Q000302:isolation & purification; D019142:Hemorrhagic Fever, Ebola / Q000175:diagnosis* / Q000453:epidemiology* / Q000517:prevention & control; D006801:Humans; D012307:Risk Factors
keywords: Ebola virus infection; chain of infection; determinants; replication number; risk factor; source; spread; transmission