title: Candidial Endocarditis: A Single-Institute Pathological Analysis.
abstract: Infective endocarditis is increasingly perceived as a byproduct of aggressive medications and/or invasive medical procedures. Some of the organisms are fungi, and in this situation, Candida species account for nearly half of all fungal IE. We report a single-institute pathological experience of 14 cases of candidial endocarditis among surgically excised cardiac tissues and autopsied cases in a 14-year period. Twelve of the 14 cases were seen as healthcare-associated invasive infections, and only five had been diagnosed antemortem. Candidial endocarditis was predominantly right-sided and valvular. The risk factors included underlying heart diseases, central venous catheterization and prolonged antibiotic therapy. Mortality among the autopsied patients was related to septicemia and/or embolic complications.
authors.affiliation: Department of Pathology (Cardiovascular and Thoracic Division), Seth GS Medical College, Parel, Mumbai, 400012, India, shreeprajai@yahoo.co.in.
authors.forename: Pradeep
authors.initials: P
authors.lastname: Vaideeswar
mesh_terms: D000293:Adolescent; D000328:Adult; D002175:Candida / Q000302:isolation & purification*; D002177:Candidiasis / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D004696:Endocarditis / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult