title: Hydrazide macrocycles as effective transmembrane channels for ammonium.
abstract: Three shape-persistent aromatic hydrazide macrocycles that bear phenylalanine tripeptide chains have been synthesized. These macrocycles can insert into lipid bilayers to form single-molecular ion channels which exhibit a high NH4(+)/K(+) selectivity.
authors.affiliation: Department of Chemistry, Collaborative Innovation Center of Chemistry for Energy Materials (iChEM), Fudan University, 220 Handan Road, Shanghai 200433, China. houjl@fudan.edu.cn ztli@fudan.edu.cn.
authors.forename: Pengyang
authors.initials: P
authors.lastname: Xin
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
authors.forename: Pei
authors.initials: P
authors.lastname: Su
authors.forename: Jun-Li
authors.initials: JL
authors.lastname: Hou
authors.forename: Zhan-Ting
authors.initials: ZT
authors.lastname: Li
mesh_terms: D064751:Ammonium Compounds / Q000737:chemistry*; D019295:Computational Biology; D008055:Lipids / Q000737:chemistry; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008567:Membranes, Artificial; D015394:Molecular Structure; D010649:Phenylalanine / Q000737:chemistry; D011188:Potassium / Q000737:chemistry
chemical_list: D064751:Ammonium Compounds; D008055:Lipids; D047028:Macrocyclic Compounds; D008567:Membranes, Artificial; D010649:Phenylalanine; D011188:Potassium