title: Cobalt-catalyzed asymmetric hydroboration of aryl ketones with pinacolborane.
abstract: The highly enantioselective cobalt-catalyzed hydroboration reaction of aryl ketones with HBpin was developed using iminopyridine oxazoline ligands. Halides, amines, ethers, sulfides, esters and amides are well tolerated under the mild reaction conditions, demonstrating its synthetic advantage. Substituted diaryl ketones could also be hydroborated with high enantioselectivity.
authors.affiliation: Department of chemistry, Zhejiang University, Hangzhou 310027, China. luzhan@zju.edu.cn.
authors.forename: Jun
authors.initials: J
authors.lastname: Guo
authors.forename: Jianhui
authors.initials: J
authors.lastname: Chen
authors.forename: Zhan
authors.initials: Z
authors.lastname: Lu
mesh_terms: D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001896:Boron Compounds; D007659:Ketones; D009942:Organometallic Compounds; D003035:Cobalt