title: A comparison of 120 W laser photoselective vaporization versus transurethral resection of the prostate for bladder outlet obstruction by prostate cancer.
abstract: OBJECTIVE
  To compare the mid-term outcomes of photoselective vaporization of prostate (PVP) with GreenLight HPS 120 W laser and transurethral resection of the prostate (TURP) for obstructive lower urinary tract symptoms (LUTS) in men with prostate cancer (CaP).
  
  
  METHODS
  Seventy four patients with locally advanced (T3/T4) CaP with severe LUTS or acute urinary retention (AUR) were allocated to TURP (n = 36) or PVP (n = 38). International Prostate Symptom Scores (IPSS), maximum flow rates (Qmax) and post-void residual volumes (Vres), PSA levels, prostate volumes, complications, catheter removal and hospitalization periods were recorded. Patients were reassessed at 3, 6, and 12 months.
  
  
  RESULTS
  The catheter removal time was significantly longer in the TURP group (3.8 ± 1.1 vs. 1.2 ± 0.7 days, p = 0.02), whereas failure of initial voiding trial was higher in PVP (2.7 vs. 13.1%, p = 0.01). No significant difference in IPSS, Qmax and Vres values was observed within the follow-up period between two groups. A significant difference in urethral stricture rate (8.3 vs. 0%), catheter removal time (3.8 ± 11 vs. 1.2 ± 0.7 days) and hospital stay (2.9 ± 0.6 vs. 1.1 ± 0.5 days) was observed in favor of PVP.
  
  
  CONCLUSIONS
  Palliative PVP is very safe and effective by means of symptomatic relief in patients with locally advanced CaP.
authors.affiliation: Department of Urology, Istanbul Medipol University, Istanbul, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Altay
authors.forename: Bulent
authors.initials: B
authors.lastname: Erkurt
authors.forename: Murat Can
authors.initials: MC
authors.lastname: Kiremit
authors.forename: Rahim
authors.initials: R
authors.lastname: Horuz
authors.forename: Vahit
authors.initials: V
authors.lastname: Guzelburc
authors.forename: Selami
authors.initials: S
authors.lastname: Albayrak
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002404:Catheterization; D006760:Hospitalization; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D007834:Lasers; D059411:Lower Urinary Tract Symptoms / Q000209:etiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011467:Prostate / Q000601:surgery; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000150:complications / Q000601:surgery* / Q000628:therapy*; D020728:Transurethral Resection of Prostate / Q000009:adverse effects*; D016896:Treatment Outcome; D001748:Urinary Bladder Neck Obstruction / Q000209:etiology*
chemical_list: D017430:Prostate-Specific Antigen