title: Management of neonatal morbidities during hypothermia treatment.
abstract: Although the primary goal of therapeutic hypothermia is to improve the neurodevelopmental outcome in asphyxiated infants, optimal management of the full range of multi-organ system complications typically presented by such infants during cooling treatment is necessary for improvement of the overall outcome. For this reason, adequate knowledge of how cooling affects all organ systems of asphyxiated infants with multi-organ hypoxic-ischemic injury is essential. Adequate diagnostic resources, readily available subspecialty consultant services and trained multidisciplinary staff to monitor and manage multi-organ system complications in asphyxiated infants during therapeutic cooling must be ensured during implementation of a cooling program. As therapeutic hypothermia is being used more widely, centers should consider participation in national or international benchmarking of outcomes and short-term adverse events during cooling to facilitate continuous quality improvement efforts.
authors.affiliation: Department of Pediatrics, Division of Neonatal-Perinatal Medicine, The University of Michigan, C.S. Mott Children's Hospital, Ann Arbor, MI, USA.
authors.forename: Subrata
authors.initials: S
authors.lastname: Sarkar
authors.affiliation: Department of Pediatrics, Division of Neonatal-Perinatal Medicine, The University of Michigan, C.S. Mott Children's Hospital, Ann Arbor, MI, USA. Electronic address: jbarks@med.umich.edu.
authors.forename: John
authors.initials: J
authors.lastname: Barks
mesh_terms: D001238:Asphyxia Neonatorum / Q000150:complications* / Q000628:therapy; D002658:Developmental Disabilities / Q000209:etiology*; D019468:Disease Management; D006801:Humans; D007036:Hypothermia, Induced; D020925:Hypoxia-Ischemia, Brain / Q000150:complications / Q000628:therapy*; D007231:Infant, Newborn
keywords: Benchmarking; Hypoxic–ischemic injury; Therapeutic hypothermia