title: Oral ulcer: an uncommon site in primary tuberculosis.
abstract: Tuberculosis is a chronic infectious disease and a major cause of morbidity and mortality worldwide. It can affect any part of the body, including the oral cavity. Oral lesions of tuberculosis, though uncommon, have been observed in both primary and secondary stages of the disease. This article presents a case of primary tuberculosis manifested as a non-healing, tender ulcer on the lingual mucosa of the edentulous right mandibular arch molar zone, an uncommon site. The diagnosis was confirmed after histopathology examination, polymerase chain reaction and purified protein derivative tests and chest radiograph. A recommended treatment plan of six months with four anti-tuberculotic antibiotics was commenced. Clinically, the oral ulcer disappeared three months after the commencement of treatment. The resurgence of tuberculosis should compel clinicians to include the disease in the differential diagnosis of various types of non-healing oral ulcers.
authors.affiliation: Oral Pathology and Diagnosis, School of Dentistry, Lebanese University, Beirut, Lebanon.
authors.forename: N
authors.initials: N
authors.lastname: Aoun
authors.forename: G
authors.initials: G
authors.lastname: El-Hajj
authors.forename: S
authors.initials: S
authors.lastname: El Toum
mesh_terms: D000368:Aged; D000904:Antibiotics, Antitubercular / Q000008:administration & dosage / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006101:Granuloma, Giant Cell / Q000175:diagnosis; D006801:Humans; D008297:Male; D009059:Mouth Diseases / Q000175:diagnosis; D009062:Mouth Neoplasms / Q000175:diagnosis; D019226:Oral Ulcer / Q000175:diagnosis*; D014393:Tuberculosis, Oral / Q000175:diagnosis*
chemical_list: D000904:Antibiotics, Antitubercular; D000995:Antitubercular Agents
keywords: Mandibular lingual mucosa; oral ulcer; primary tuberculosis