title: [Lung perfusion studies after percutaneous closure of patent ductus arteriosus using the Amplatzer Duct Occluder in children].
abstract: OBJECTIVE
  The closure of patent ductus arteriosus with multiple devices has been associated with a reduction in lung perfusion. We evaluated the pulmonary perfusion after percutaneous closure of patent ductus arteriosus with the Amplatzer Duct Occluder device using perfusion lung scan.
  
  
  METHODS
  Thirty patients underwent successful percutaneous patent ductus arteriosus occlusions using the Amplatzer Duct Occluder device were included in this study. Lung perfusion scans were preformed 6 months after the procedure. Peak flow velocities and protrusion of the device were analyzed by Doppler echocardiography. A left lung perfusion<40% was considered abnormal.
  
  
  RESULTS
  The device implantation was successful in all patients. Average perfusion of left lung was 44.7±4.9% (37.8-61.4). Five patients (16.6%) showed decreased perfusion of the left lung. Age, low weight, the length of the ductus arteriosus and the minimum and maximum diameter/length of the ductus arteriosus ratio were statistically significant in patients with abnormalities of lung perfusion. It was observed protrusion the device in 6 patients with a higher maximum flow rate in the left pulmonary artery.
  
  
  CONCLUSIONS
  The left lung perfusion may be compromised after percutaneous closure of patent ductus arteriosus with the Amplatzer Duct Occluder. The increased flow velocity in the origin of the left pulmonary artery can be a poor indicator of reduction in pulmonary perfusion and can occur in the absence of protrusion of the device.
authors.affiliation: Servicio de Cardiología y Hemodinamia, Hospital de Pediatría Centro Médico Nacional Siglo XXI Instituto Mexicano del Seguro Social, México, Distrito Federal, México. Electronic address: rafaelparrabravo@yahoo.com.mx.
authors.forename: José Rafael
authors.initials: JR
authors.lastname: Parra-Bravo
authors.affiliation: Servicio de Pediatría, Hospital de Pediatría Centro Médico Nacional Siglo XXI Instituto Mexicano del Seguro Social, México, Distrito Federal, México.
authors.forename: Adriana
authors.initials: A
authors.lastname: Apolonio-Martínez
authors.affiliation: Servicio de Cardiología y Hemodinamia, Hospital de Pediatría Centro Médico Nacional Siglo XXI Instituto Mexicano del Seguro Social, México, Distrito Federal, México.
authors.forename: María de Jesús
authors.initials: Mde J
authors.lastname: Estrada-Loza
authors.affiliation: Servicio de Cardiología y Hemodinamia, Hospital de Pediatría Centro Médico Nacional Siglo XXI Instituto Mexicano del Seguro Social, México, Distrito Federal, México.
authors.forename: Luisa Gracia
authors.initials: LG
authors.lastname: Beirana-Palencia
authors.affiliation: Servicio de Cardiología y Hemodinamia, Hospital de Pediatría Centro Médico Nacional Siglo XXI Instituto Mexicano del Seguro Social, México, Distrito Federal, México.
authors.forename: César Iván
authors.initials: CI
authors.lastname: Ramírez-Portillo
mesh_terms: D002675:Child, Preschool; D004374:Ductus Arteriosus, Patent / Q000503:physiopathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D008168:Lung / Q000098:blood supply*; D008297:Male; D011651:Pulmonary Artery / Q000503:physiopathology*; D012039:Regional Blood Flow; D012189:Retrospective Studies; D055989:Septal Occluder Device
keywords: Amplatzer Duct Occluder; Cierre percutáneo; Conducto arterioso permeable; Gammagrafía pulmonar; Lung perfusion scan; México; Patent ductus arteriosus; Percutaneous closure