title: Patient perception of postoperative pain after administration of liposomal bupivacaine in plastic surgery.
abstract: BACKGROUND
  Since obtaining FDA approval for postsurgical pain management in 2011, a number of well-designed studies have reported favorably on the safety and efficacy of liposomal bupivacaine (LB). However, the literature lacks adequate reports of patient perception of postoperative pain and subjective satisfaction.
  
  
  METHODS
  A telephone survey of patients who received LB injection at time of operation at a single institution was contacted. Included were patients who underwent cosmetic, reconstructive, and/or breast procedures. Patients were asked to report their perception of pain on post-operative day (POD) 1 and 3 using the verbal scale (1-10). Additionally, patients reported on: understanding of medications received, overall satisfaction, perception of economic value, and perception of preference to elastomeric pump.
  
  
  RESULTS
  A total of 75 patients met inclusion criteria and could be reached by telephone; 23(31%) cosmetic and 52(69%) reconstructive and/or breast procedures. Mean pain score reported 2.6 (0-9) POD 1 and 3.6 (0-8) POD 3.Thirty-six (48%) patients were aware they had received the medication. Seventy-three (98%) reported they would want LB again if they needed surgery in the future and would pay U.S. $230 [$100-$1000] for the medication. All (100%) patients favored LB over a perceived elastomeric pump device.
  
  
  CONCLUSIONS
  Patient perception of efficacy after the injection of LB correlates with previous clinical findings. Our experience with LB injections for cosmetic and reconstructive breast procedures indicates that patients experienced low postoperative pain scores with high overall patient satisfaction. Additional studies comparing the use of LB to standard narcotic regimens and its use in multimodality pain management are warranted.
authors.affiliation: From the Cleveland Clinic Florida Weston, FL.
authors.forename: Nathan
authors.initials: N
authors.lastname: Eberle
authors.forename: Martin
authors.initials: M
authors.lastname: Newman
mesh_terms: D000779:Anesthetics, Local / Q000627:therapeutic use*; D002045:Bupivacaine / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007267:Injections; D008081:Liposomes; D010147:Pain Measurement; D058748:Pain Perception; D010149:Postoperative Pain / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D017060:Patient Satisfaction; D019651:Plastic Surgery Procedures; D012189:Retrospective Studies
chemical_list: D000779:Anesthetics, Local; D008081:Liposomes; D002045:Bupivacaine