title: Free-standing gold-nanoparticle monolayer film fabricated by protein self-assembly of α-synuclein.
abstract: Free-standing nanoparticle films are of great importance for developing future nano-electronic devices. We introduce a protein-based fabrication strategy of free-standing nanoparticle monolayer films. α-Synuclein, an amyloidogenic protein, was utilized to yield a tightly packed gold-nanoparticle monolayer film interconnected by protein β-sheet interactions. Owing to the stable protein-protein interaction, the film was successfully expanded to a 4-inch diameter sheet, which has not been achieved with any other free-standing nanoparticle monolayers. The film was flexible in solution, so it formed a conformal contact, surrounding even microspheres. Additionally, the monolayer film was readily patterned at micrometer-scale and thus unprecedented double-component nanoparticle films were fabricated. Therefore, the free-floating gold-nanoparticle monolayer sheets with these properties could make the film useful for the development of bio-integrated nano-devices and high-performance sensors.
authors.affiliation: School of Chemical and Biological Engineering, Institute of Chemical Processes, College of Engineering, Seoul National University, Seoul 151-744 (Korea).
authors.forename: Junghee
authors.initials: J
authors.lastname: Lee
authors.forename: Ghibom
authors.initials: G
authors.lastname: Bhak
authors.forename: Ji-Hye
authors.initials: JH
authors.lastname: Lee
authors.forename: Woohyun
authors.initials: W
authors.lastname: Park
authors.forename: Minwoo
authors.initials: M
authors.lastname: Lee
authors.forename: Daekyun
authors.initials: D
authors.lastname: Lee
authors.forename: Noo Li
authors.initials: NL
authors.lastname: Jeon
authors.forename: Dae H
authors.initials: DH
authors.lastname: Jeong
authors.forename: Kookheon
authors.initials: K
authors.lastname: Char
authors.forename: Seung R
authors.initials: SR
authors.lastname: Paik
keywords: nanoparticles; protein-protein interactions; self-assembly; supramolecular chemistry; thin films