title: Effects of adult male circumcision on premature ejaculation: results from a prospective study in China.
abstract: The purpose of this study is to investigate the effects of adult male circumcision on premature ejaculation (PE). Therefore, between December 2009 and March 2014, a total of 575 circumcised men and 623 uncircumcised men (control group) were evaluated. Detailed evaluations (including circumcision and control groups) on PE were conducted before circumcision and at the 3-, 6-, 9-, and 12-month follow-up visits after circumcision. Self-estimated intravaginal ejaculatory latency time (IELT), Patient-Reported Outcome measures, and 5-item version of the International Index of Erectile Function were used to measure the ejaculatory and erectile function for all subjects. The results showed that, during the one-year follow-up, men after circumcision experienced higher IELT and better scores of control over ejaculation, satisfaction with sexual intercourse, and severity of PE than men before circumcision (P < 0.001 for all). Similarly, when compared with the control group, the circumcised men reported significantly improved IELT, control over ejaculation, and satisfaction with sexual intercourse (P < 0.001 for all). These findings suggested that circumcision might have positive effects on IELT, ejaculatory control, sexual satisfaction, and PE severity. In addition, circumcision was significantly associated with the development of PE.
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Jingjing
authors.identifier: 0000-0003-4226-3944
authors.initials: J
authors.lastname: Gao
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Chuan
authors.initials: C
authors.lastname: Xu
authors.affiliation: Department of Radiology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Jingjing
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Chaozhao
authors.initials: C
authors.lastname: Liang
authors.affiliation: Academy of Public Health, The Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Puyu
authors.initials: P
authors.lastname: Su
authors.affiliation: Academy of Public Health, The Xiangya School of Medicine, The Central South University, Changsha, Hunan 410000, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Peng
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Shi
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Dongdong
authors.initials: D
authors.lastname: Tang
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Pan
authors.initials: P
authors.lastname: Gao
authors.affiliation: Department of Urology, The Chaohu Affiliated Hospital of Anhui Medical University, Chaohu, Anhui 238000, China.
authors.forename: Zhaoxiang
authors.initials: Z
authors.lastname: Lu
authors.affiliation: Department of Urology, The Anqing Affiliated Hospital of Anhui Medical University, Anqing, Anhui 246000, China.
authors.forename: Jishuang
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Urology, The Huaibei Affiliated Hospital of Anhui Medical University, Huaibei, Anhui 235000, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Xia
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Jiajia
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Zongyao
authors.initials: Z
authors.lastname: Hao
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhou
authors.affiliation: Department of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China.
authors.forename: Xiansheng
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002681:China; D002944:Circumcision, Male / Q000009:adverse effects*; D003075:Coitus / Q000502:physiology; D006801:Humans; D008297:Male; D061686:Premature Ejaculation / Q000503:physiopathology*; D011446:Prospective Studies; D011795:Surveys and Questionnaires