title: Identification of essential outstanding questions for an adequate  European laboratory response to Ebolavirus Zaire West Africa 2014.
abstract: On August 8 2014, the World Health Organization (WHO) declared the outbreak of Ebola Virus Disease (EVD) evolving in West Africa since December 2013, a Public Health Emergency of International Concern (PHEIC). It is expected that the outbreak of Ebolavirus Disease (EVD) in West Africa will lead to increased testing of individuals in Europe for EVD. The severity of the situation in West Africa warranted a critical appraisal of the laboratory preparedness and response for EVD, with a focus on information needs for laboratories involved in diagnostics of rare viral diseases associated with the European Network for the Diagnostics of "Imported" Viral Diseases", ENIVD. Essential knowledge and knowledge gaps for an adequate laboratory response focusing on virus properties, infection kinetics, tests specifics and field performances were identified. An inventory of the laboratory capacity for EVD diagnostics among ENIVD laboratories was made.
authors.forename: Chantal
authors.initials: C
authors.lastname: Reusken
authors.forename: Matthias
authors.initials: M
authors.lastname: Niedrig
authors.forename: Suzan
authors.initials: S
authors.lastname: Pas
authors.forename: Pedro
authors.initials: P
authors.lastname: Anda
authors.forename: Sylvain
authors.initials: S
authors.lastname: Baize
authors.forename: Remi
authors.initials: R
authors.lastname: Charrel
authors.forename: Antonino
authors.initials: A
authors.lastname: Di Caro
authors.forename: Christian
authors.initials: C
authors.lastname: Drosten
authors.forename: Maria Dolores
authors.initials: MD
authors.lastname: Fernandez-Garcia
authors.forename: Leticia
authors.initials: L
authors.lastname: Franco
authors.forename: Stephan
authors.initials: S
authors.lastname: Gunther
authors.forename: Isabelle
authors.initials: I
authors.lastname: Leparc-Goffart
authors.forename: Byron
authors.initials: B
authors.lastname: Martina
authors.forename: Delphine
authors.initials: D
authors.lastname: Pannetier
authors.forename: Anna
authors.initials: A
authors.lastname: Papa
authors.forename: Maria Paz
authors.initials: MP
authors.lastname: Sanchez-Seco
authors.forename: Olli
authors.initials: O
authors.lastname: Vapalahti
authors.forename: Marion
authors.initials: M
authors.lastname: Koopmans
mesh_terms: D000354:Africa, Western / Q000453:epidemiology; D000465:Algorithms; D064790:Clinical Laboratory Services; D004196:Disease Outbreaks; D029043:Ebolavirus / Q000145:classification / Q000235:genetics; D005060:Europe / Q000453:epidemiology; D014644:Genetic Variation; D062306:Geography, Medical; D019142:Hemorrhagic Fever, Ebola / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D006801:Humans; D058889:Molecular Typing / Q000379:methods / Q000592:standards; D011159:Population Surveillance; D015203:Reproducibility of Results; D018570:Risk Assessment; D012680:Sensitivity and Specificity; D012703:Serotyping / Q000379:methods / Q000592:standards