title: Polymorphisms in oxytocin and α1a adrenergic receptor genes and their effects on production traits in dairy buffaloes.
abstract: The use of molecular markers may auxiliary the buffalo breeding. The oxytocin (OXT) and the adrenergic receptor α1A (ADRA1A) may be involved in milk ejection in ruminants. The aim of this study was to verify the existence of polymorphisms in the OXT and ADRA1A genes and their associations with milk production traits. A total of 220 buffaloes were genotyped using PCR-RFLP for both genes. The SNP identified in the ADRA1A gene was associated with protein percentage in dairy buffaloes. This is the first report of such association in the literature, which has not been studied in other species.
authors.affiliation: a Faculdade de Ciências Agrárias e Veterinárias, Departamento de Zootecnia , São Paulo State University (Unesp) , Jaboticabal , Sao Paulo , Brazil.
authors.forename: Daniele Neves
authors.initials: DN
authors.lastname: Araújo
authors.forename: Gregório Miguel Ferreira
authors.initials: GM
authors.lastname: de Camargo
authors.forename: Patrícia
authors.initials: P
authors.lastname: Dias da Silva Fonseca
authors.forename: Diercles Francisco
authors.initials: DF
authors.lastname: Cardoso
authors.forename: Naudin Alejandro
authors.initials: NA
authors.lastname: Hurtado-Lugo
authors.forename: Rúsbel Raul
authors.initials: RR
authors.lastname: Aspilcueta-Borquis
authors.forename: Humberto
authors.initials: H
authors.lastname: Tonhati
mesh_terms: D000818:Animals; D002020:Buffaloes / Q000235:genetics*; D003612:Dairying; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D007774:Lactation / Q000235:genetics*; D008892:Milk / Q000737:chemistry; D010121:Oxytocin / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D018340:Receptors, Adrenergic, alpha-1 / Q000235:genetics*
chemical_list: D005819:Genetic Markers; D018340:Receptors, Adrenergic, alpha-1; D010121:Oxytocin
keywords: Bubalis bubalis; Milk ejection; Molecular markers; SNP