title: Limb deformity in a newborn. Is rifampicin just an innocent bystander?
abstract: OBJECTIVE
  The first-line antituberculous agents for use during pregnancy have minimal teratogenic effects. The possibility of limb deformity during rifampin use, however, was reported by some researchers.
  
  
  METHODS
  A male newborn was born with a hypoplastic right forearm to a mother with tuberculosis who used isoniazid and rifampicin in the first two months of her pregnancy.
  
  
  CONCLUSIONS
  The limb anomaly in our case might be attributed to rifampicin usage during the first 2 months of pregnancy. Caution should be given with regard to possible congenital malformations which could be associated with the treatment of pregnant women with antituberculous drugs.
authors.affiliation: Department of Pediatrics, Department of Neonatology, Ministry of Health, Kanuni Sultan Suleyman Teaching and Research Hospital, Istanbul, Turkey. tugbaerener@yahoo.com.
authors.forename: T
authors.initials: T
authors.lastname: Kalayci
authors.forename: T
authors.initials: T
authors.lastname: Erener-Ercan
authors.forename: G
authors.initials: G
authors.lastname: Buyukkale
authors.forename: M
authors.initials: M
authors.lastname: Cetinkaya
mesh_terms: D000995:Antitubercular Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000188:drug therapy*; D012293:Rifampin / Q000009:adverse effects*; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy*; D038062:Upper Extremity Deformities, Congenital / Q000139:chemically induced* / Q000175:diagnosis*; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents; D012293:Rifampin