title: Development of a flow method for the hydroboration/oxidation of olefins.
abstract: A method for the continuous preparation of alcohols by hydroboration/oxidation of olefins using flow techniques is described. The process allows the isolation of up to 120 mmol h(-1) of the desired alcohol in a very rapid manner with good functional group tolerance. The flow setup can be modified to perform a continuous extraction of the desired alcohol from the biphasic mixture produced by the reaction.
authors.affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK. svl1000@cam.ac.uk.
authors.forename: José A
authors.initials: JA
authors.lastname: Souto
authors.forename: Robert A
authors.initials: RA
authors.lastname: Stockman
authors.forename: Steven V
authors.initials: SV
authors.lastname: Ley
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001895:Boron / Q000737:chemistry*; D010084:Oxidation-Reduction; D012997:Solvents / Q000737:chemistry
chemical_list: D000475:Alkenes; D012997:Solvents; D001895:Boron