title: [Analysis of the quality of cryopreserved semen from male cancer patients].
abstract: OBJECTIVE
  To investigate the semen quality of cancer patients and search for a better way of sperm cryopreservation for them.
  
  
  METHODS
  We retrospectively analyzed the quality of the semen from 43 cancer patients under cryopreservation in the Sperm Bank of Zhejiang Province, and compared the semen parameters between the cancer patients and 248 normal donors as well as between the testicular cancer cases (n=22) and non-testicular cancer cases (n=21).
  
  
  RESULTS
  The cancer patients exhibited significantly lower semen quality than the normal donors as in sperm concentration (60.90 x 10(6)/ml vs 74.27 x 10(6)/ml), progressive motility (41.07% vs 51.79%), and recovery rate (49.98% vs 57.33%) (all P <0.05). Furthermore, the progressive sperm motility and sperm recovery rate after freezing were significantly decreased in the testicular cancer cases (15.68% and 42.81%) than in the non-testicular cancer cases (28.36% and 57.53%) (both P <0.05).
  
  
  CONCLUSIONS
  Semen quality declines in cancer patients, and therefore early sperm cryopreservation is essential for them. Due to the poor sperm motility and recovery rate of testicular cancer patients after freezing, further investigation is required on the improvement of sperm cryopreservation methods.
authors.forename: Hui-qiang
authors.initials: HQ
authors.lastname: Sheng
authors.forename: Xin-zong
authors.initials: XZ
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Hong
mesh_terms: D000328:Adult; D015925:Cryopreservation / Q000379:methods*; D006801:Humans; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal; D012661:Semen; D055101:Semen Analysis; D012662:Semen Preservation / Q000379:methods*; D013076:Sperm Count; D013081:Sperm Motility; D013736:Testicular Neoplasms