title: Comprehensive study of back and leg pain improvements after adult spinal deformity surgery: analysis of 421 patients with 2-year follow-up and of the impact of the surgery on treatment satisfaction.
abstract: OBJECT Back and leg pain are the primary outcomes of adult spinal deformity (ASD) and predict patients' seeking of surgical management. The authors sought to characterize changes in back and leg pain after operative or nonoperative management of ASD. Outcomes were assessed according to pain severity, type of surgical procedure, Scoliosis Research Society (SRS)-Schwab spine deformity class, and patient satisfaction. METHODS This study retrospectively reviewed data in a prospective multicenter database of ASD patients. Inclusion criteria were the following: age > 18 years and presence of spinal deformity as defined by a scoliosis Cobb angle ≥ 20°, sagittal vertical axis length ≥ 5 cm, pelvic tilt angle ≥ 25°, or thoracic kyphosis angle ≥ 60°. Patients were grouped into nonoperated and operated subcohorts and by the type of surgical procedure, spine SRS-Schwab deformity class, preoperative pain severity, and patient satisfaction. Numerical rating scale (NRS) scores of back and leg pain, Oswestry Disability Index (ODI) scores, physical component summary (PCS) scores of the 36-Item Short Form Health Survey, minimum clinically important differences (MCIDs), and substantial clinical benefits (SCBs) were assessed. RESULTS Patients in whom ASD had been operatively managed were 6 times more likely to have an improvement in back pain and 3 times more likely to have an improvement in leg pain than patients in whom ASD had been nonoperatively managed. Patients whose ASD had been managed nonoperatively were more likely to have their back or leg pain remain the same or worsen. The incidence of postoperative leg pain was 37.0% at 6 weeks postoperatively and 33.3% at the 2-year follow-up (FU). At the 2-year FU, among patients with any preoperative back or leg pain, 24.3% and 37.8% were free of back and leg pain, respectively, and among patients with severe (NRS scores of 7-10) preoperative back or leg pain, 21.0% and 32.8% were free of back and leg pain, respectively. Decompression resulted in more patients having an improvement in leg pain and their pain scores reaching MCID. Although osteotomies improved back pain, they were associated with a higher incidence of leg pain. Patients whose spine had an SRS-Schwab coronal curve Type N deformity (sagittal malalignment only) were least likely to report improvements in back pain. Patients with a Type L deformity were most likely to report improved back or leg pain and to have reductions in pain severity scores reaching MCID and SCB. Patients with a Type D deformity were least likely to report improved leg pain and were more likely to experience a worsening of leg pain. Preoperative pain severity affected pain improvement over 2 years because patients who had higher preoperative pain severity experienced larger improvements, and their changes in pain severity were more likely to reach MCID/SCB than for those reporting lower preoperative pain. Reductions in back pain contributed to improvements in ODI and PCS scores and to patient satisfaction more than reductions in leg pain did. CONCLUSIONS The authors' results provide a valuable reference for counseling patients preoperatively about what improvements or worsening in back or leg pain they may experience after surgical intervention for ASD.
authors.affiliation: Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois;
authors.forename: Justin K
authors.initials: JK
authors.lastname: Scheer
authors.forename: Justin S
authors.initials: JS
authors.lastname: Smith
authors.forename: Aaron J
authors.initials: AJ
authors.lastname: Clark
authors.forename: Virginie
authors.initials: V
authors.lastname: Lafage
authors.forename: Han Jo
authors.initials: HJ
authors.lastname: Kim
authors.forename: John D
authors.initials: JD
authors.lastname: Rolston
authors.forename: Robert
authors.initials: R
authors.lastname: Eastlack
authors.forename: Robert A
authors.initials: RA
authors.lastname: Hart
authors.forename: Themistocles S
authors.initials: TS
authors.lastname: Protopsaltis
authors.forename: Michael P
authors.initials: MP
authors.lastname: Kelly
authors.forename: Khaled
authors.initials: K
authors.lastname: Kebaish
authors.forename: Munish
authors.initials: M
authors.lastname: Gupta
authors.forename: Eric
authors.initials: E
authors.lastname: Klineberg
authors.forename: Richard
authors.initials: R
authors.lastname: Hostin
authors.forename: Christopher I
authors.initials: CI
authors.lastname: Shaffrey
authors.forename: Frank
authors.initials: F
authors.lastname: Schwab
authors.forename: Christopher P
authors.initials: CP
authors.lastname: Ames
mesh_terms: D001416:Back Pain / Q000209:etiology / Q000601:surgery*; D019299:Decompression, Surgical; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D007866:Leg; D008297:Male; D008875:Middle Aged; D010027:Osteotomy; D010146:Pain / Q000209:etiology / Q000601:surgery*; D010147:Pain Measurement; D017060:Patient Satisfaction; D011788:Quality of Life; D012189:Retrospective Studies; D013131:Spine / Q000002:abnormalities* / Q000601:surgery; D016896:Treatment Outcome; D014481:United States
keywords: ASD = adult spinal deformity; FU = follow-up; HRQOL = health-related quality of life; MCID = minimum clinically import difference; NRS = numerical rating scale; ODI = Oswestry Disability Index; PCS = physical component summary; PSO; SCB = substantial clinical benefit; SF-36 = 36-Item Short Form Health Survey; SRS = Scoliosis Research Society; SRS-Schwab classification; VCR; adult spinal deformity; back pain; leg pain; satisfaction; scoliosis; spinal disorders