title: Supracricoid laryngectomies: oncological and functional results for 152 patients.
abstract: The purpose of this study was to evaluate the oncological and functional outcomes in patients who underwent supracricoid laryngectomies with a crico-hyoidopexy (SCL-CHP) or a crico-hyoido-epiglottopexy (SCL-CHEP) for the treatment of primary and reccurent laryngeal cancer. A retrospective study was conducted on 152 consecutive patients seen from January 1996 to December 2006. Overall survival (OS) and disease-free survival (DFS) were analysed using the Kaplan-Meier method, and were compared according to the type of surgery and clinical stage of the tumour. The mean period before decannulation, nasogastric tube (NGT) removal and recovery of a normal diet and speech were evaluated, and statistical analyses were performed regarding the association with the type of surgery and arytenoidectomy. The median follow-up period was 49.9 months (range: 10-110 months). The 3- and 5-year OS were 87.5 and 83.5%, respectively, and 3- and 5-year DFS were 78.3 and 73.7%, respectively. For patients with early stages tumours, the 5-year OS and DFS were 92.3 and 84.6% respectively, whereas for patients with locally advanced stage tumours, the OS and DFS were 74.3 and 62.2%, respectively. Significant differences in OS and DFS for patients who had early or locally advanced cancers were found (p = 0.0004 and p = 0.0032, respectively). The rate of overall local control was 92.1%, while the mean period until decannulation or NGT removal was 25.1 and 16.6 days, respectively. The mean period until NGT removal was significantly different according to the type of surgery (p = 0.0001) and whether arytenoidectomy was performed (p = 0.0001). The reliable oncological and functional results of SCL for early and locally advanced laryngeal cancers are confirmed by our series of patients.
authors.affiliation: Otolaryngology Head and Neck Surgery Unit of "Azienda Ospedaliera di Rilievo Nazionale dei Colli - Ospedale Monaldi", Naples, Italy.
authors.forename: C A
authors.initials: CA
authors.lastname: Leone
authors.affiliation: Otolaryngology Head and Neck Surgery Unit of "Azienda Ospedaliera di Rilievo Nazionale dei Colli - Ospedale Monaldi", Naples, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Capasso
authors.affiliation: Otolaryngology Head and Neck Surgery Unit of "Azienda Ospedaliera di Rilievo Nazionale dei Colli - Ospedale Monaldi", Naples, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Russo
authors.affiliation: Otolaryngology Head and Neck Surgery Unit of "Azienda Ospedaliera di Rilievo Nazionale dei Colli - Ospedale Monaldi", Naples, Italy.
authors.forename: P
authors.initials: P
authors.lastname: D'Errico
authors.affiliation: Otolaryngology Head and Neck Surgery Unit of "Azienda Ospedaliera di Rilievo Nazionale dei Colli - Ospedale Monaldi", Naples, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Cutillo
authors.affiliation: Otolaryngology Head and Neck Surgery Unit of "Azienda Ospedaliera di Rilievo Nazionale dei Colli - Ospedale Monaldi", Naples, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Orabona
mesh_terms: D000328:Adult; D000368:Aged; D003413:Cricoid Cartilage; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: Functional outcome; Laryngeal cancer; Organ-preserving surgery; Supracricoid laryngectomies