title: An unusual large abdominal malakoplakia following trauma: Diagnosed on FNAC.
abstract: Malakoplakia is a rare chronic granulomatous inflammatory disease, related to immune deficiency and impaired bactericidal macrophage activity. Common sites of involvement include urinary bladder and kidney followed by gastrointestinal tract. We present an unusual case of abdominal malakoplakia diagnosed preoperatively on ultrasound-guided fine-needle aspiration cytology (FNAC). It presented as a large locally aggressive mass with extensive involvement of multiple bowel loops in an 18-year-old boy following blunt trauma to the abdomen. The demonstration of calcified laminated intracytoplasmic Michaelis-Gutman bodies in histiocytes is a reliable diagnostic feature of malakoplakia on FNAC smears, which can guide an appropriate medical management.
authors.affiliation: Department of Pathology, University College of Medical Sciences & GTB Hospital, Delhi, India.
authors.forename: Surbhi
authors.initials: S
authors.lastname: Goyal
authors.forename: Asmita
authors.initials: A
authors.lastname: Parihar
authors.forename: Vandana
authors.initials: V
authors.lastname: Puri
authors.forename: Naveen
authors.initials: N
authors.lastname: Sharma
authors.forename: Ankur
authors.initials: A
authors.lastname: Goyal
authors.forename: Vinod Kumar
authors.initials: VK
authors.lastname: Arora
mesh_terms: D000007:Abdominal Injuries / Q000150:complications*; D000293:Adolescent; D044963:Biopsy, Fine-Needle; D006801:Humans; D008287:Malacoplakia / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D008297:Male
keywords: FNAC; Michaelis-Gutman bodies; abdominal malakoplakia