title: Distribution of DTX-3 in edible and non-edible parts of Crenomytilus grayanus from the Sea of Japan.
abstract: Seasonal dynamics and the distribution of dinophysistoxin-3 (DTX-3) in organs of mussel Crenomytilus grayanus, collected in 2013 in Peter the Great Bay, Sea of Japan, were determined. Active toxin forms (OA, DTX-1/2) concentrated in digestive glands (60-80%), whereas non-active 7-O-acyl derivatives (DTX-3) were more abundant in edible soft tissues (more than 80%). Possible mechanism of fast removing of DTX-3 from the digestive gland and accumulation of DTX-3 in the soft tissues is supposed.
authors.affiliation: A.V. Zhirmunsky Institute of Marine Biology of the Far Eastern Branch of the Russian Academy of Sciences, 17 Palchevskogo st., Vladivostok 690041, Russia; Far Eastern Federal University, 8 Suhanova st., Vladivostok 690950, Russia. Electronic address: popkovap@mail.ru.
authors.forename: P A
authors.initials: PA
authors.lastname: Kameneva
authors.affiliation: A.V. Zhirmunsky Institute of Marine Biology of the Far Eastern Branch of the Russian Academy of Sciences, 17 Palchevskogo st., Vladivostok 690041, Russia.
authors.forename: A B
authors.initials: AB
authors.lastname: Imbs
authors.affiliation: A.V. Zhirmunsky Institute of Marine Biology of the Far Eastern Branch of the Russian Academy of Sciences, 17 Palchevskogo st., Vladivostok 690041, Russia.
authors.forename: T Yu
authors.initials: TY
authors.lastname: Orlova
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D007564:Japan; D008387:Marine Toxins / Q000493:pharmacokinetics*; D049879:Mytilidae / Q000737:chemistry*; D019319:Okadaic Acid / Q000031:analogs & derivatives; D011714:Pyrans / Q000493:pharmacokinetics*; D012758:Shellfish / Q000032:analysis*; D014018:Tissue Distribution
chemical_list: D008387:Marine Toxins; D011714:Pyrans; C092883:dinophysistoxin 3; D019319:Okadaic Acid; C076221:dinophysistoxin 2
keywords: Anatomical distribution; Crenomytilus grayanus; DTX-3; Diarrhetic shellfish toxins; ELISA