title: A prospective study of the immune system activation biomarker neopterin and colorectal cancer risk.
abstract: BACKGROUND
  Neopterin may be relevant for colorectal cancer (CRC) development, as a biomarker of cellular immune activity exerting pleiotropic effects on cellular ageing, oxidative stress, and inflammation. So far, the association between prediagnostic neopterin and colon and rectal cancer risk has not been evaluated in human populations.
  
  
  METHODS
  A nested case-control study was conducted within the European Prospective Investigation into Cancer and Nutrition cohort using data on plasma concentrations of total neopterin (T-N, sum of neopterin and 7,8-dihydroneopterin) in 830 incident CRC case patients (561 colon and 269 rectal) matched within risk sets to 830 control participants. A subsequent replication study used data from the Hordaland Health Study, where 173 CRC case patients have been diagnosed among 6594 healthy participants over 12 years of follow-up.
  
  
  RESULTS
  After multivariable adjustment for a priori chosen CRC risk factors, a "U-shaped" association of T-N with CRC was revealed. Compared with the second quintile of the T-N distribution, the relative risks for the first, third, fourth, and fifth quintiles were 2.37 (95% CI = 1.66 to 3.39), 1.24 (95% CI = 0.87 to 1.77), 1.55 (95% CI = 1.08 to 2.22), and 2.31 (95% CI = 1.63 to 3.27), respectively. Replication of these associations within the Hordaland Health Study yielded similar results. No differences have been observed when the associations were explored by colon and rectal cancer site (two-sided P difference = .87) and after excluding case patients diagnosed within the first four follow-up years.
  
  
  CONCLUSIONS
  These novel findings provide evidence of the role of both suppressed and activated cell-mediated immunity as reflected by prediagnostic T-N concentrations in the development of CRC.
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Krasimira
authors.initials: K
authors.lastname: Aleksandrova
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Shu-Chun
authors.initials: SC
authors.lastname: Chuang
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Heiner
authors.initials: H
authors.lastname: Boeing
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Hui
authors.initials: H
authors.lastname: Zuo
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Grethe S
authors.initials: GS
authors.lastname: Tell
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Tobias
authors.initials: T
authors.lastname: Pischon
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Mazda
authors.initials: M
authors.lastname: Jenab
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Bas
authors.initials: B
authors.lastname: Bueno-de-Mesquita
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Stein Emil
authors.initials: SE
authors.lastname: Vollset
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Øivind
authors.initials: Ø
authors.lastname: Midttun
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Per Magne
authors.initials: PM
authors.lastname: Ueland
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Veronika
authors.initials: V
authors.lastname: Fedirko
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Mattias
authors.initials: M
authors.lastname: Johansson
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Elisabete
authors.initials: E
authors.lastname: Weiderpass
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Gianluca
authors.initials: G
authors.lastname: Severi
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Antoine
authors.initials: A
authors.lastname: Racine
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Boutron-Ruault
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Rudolf
authors.initials: R
authors.lastname: Kaaks
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Tilman
authors.initials: T
authors.lastname: Kühn
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Anne
authors.initials: A
authors.lastname: Tjønneland
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Kim
authors.initials: K
authors.lastname: Overvad
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: J Ramón
authors.initials: JR
authors.lastname: Quirós
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Paula
authors.initials: P
authors.lastname: Jakszyn
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: María-José
authors.initials: MJ
authors.lastname: Sánchez
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Miren
authors.initials: M
authors.lastname: Dorronsoro
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Maria-Dolores
authors.initials: MD
authors.lastname: Chirlaque
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Eva
authors.initials: E
authors.lastname: Ardanaz
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Kay-Tee
authors.initials: KT
authors.lastname: Khaw
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Wareham
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Ruth C
authors.initials: RC
authors.lastname: Travis
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Antonia
authors.initials: A
authors.lastname: Trichopoulou
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Pagona
authors.initials: P
authors.lastname: Lagiou
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Trichopoulos
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Domenico
authors.initials: D
authors.lastname: Palli
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Sabina
authors.initials: S
authors.lastname: Sieri
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Rosario
authors.initials: R
authors.lastname: Tumino
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Salvatore
authors.initials: S
authors.lastname: Panico
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Anne M
authors.initials: AM
authors.lastname: May
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Richard
authors.initials: R
authors.lastname: Palmqvist
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Ingrid
authors.initials: I
authors.lastname: Ljuslinder
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: So Yeon J
authors.initials: SY
authors.lastname: Kong
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Heinz
authors.initials: H
authors.lastname: Freisling
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Marc J
authors.initials: MJ
authors.lastname: Gunter
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Yunxia
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Amanda J
authors.initials: AJ
authors.lastname: Cross
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Elio
authors.initials: E
authors.lastname: Riboli
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrueke, Nuthetal, Germany (KA, HB); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK (SCC, BBdM, MJG, YL, AJC, ER, PV); Division of Health Policy Translation, Institutes of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan (SCC); Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway (HZ, GST); Molecular Epidemiology Group, Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany (TP); International Agency for Research on Cancer, Lyon, France (MJe, SYJK, HF, MJo); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (BBdM); Department of Gastroenterology and Hepatology, University Medical Center, Utrecht, the Netherlands (BBdM); Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway (SEV); Division of Epidemiology, Norwegian Institute of Public Health, Bergen, Norway (SEV); Bevital AS, Bergen, Norway (ØM); Section for Pharmacology, Department of Clinical Science, University of Bergen, Bergen, Norway (HZ, PMU); Laboratory of Clinical Biochemistry, Haukeland University Hospital, Bergen, Norway (PMU); Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (VF); Winship Cancer Institute, Emory University, Atlanta, GA (VF); Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway (EW); Department of Research, Cancer Registry of Norway, Oslo, Norway (EW); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (EW); Samfundet Folkhälsan, Helsinki, Finland (EW); Human Genetics Foundation (HuGeF), Torino, Italy (GS, PV); Inserm, Centre for research in Epidemiology and Population Health, U1018, Nutrition, Hormones and Women's Health team, F-94805, Villeju
authors.forename: Paolo
authors.initials: P
authors.lastname: Vineis
mesh_terms: D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D016022:Case-Control Studies; D002853:Chromatography, Liquid; D003110:Colonic Neoplasms / Q000097:blood / Q000276:immunology; D015179:Colorectal Neoplasms / Q000097:blood* / Q000276:immunology*; D005060:Europe; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D019798:Neopterin / Q000031:analogs & derivatives / Q000097:blood*; D016017:Odds Ratio; D011446:Prospective Studies; D012004:Rectal Neoplasms / Q000097:blood / Q000276:immunology; D012680:Sensitivity and Specificity; D006377:T-Lymphocytes, Helper-Inducer; D053719:Tandem Mass Spectrometry
chemical_list: D014408:Biomarkers, Tumor; C000976:7,8-dihydroneopterin; D019798:Neopterin