title: The Development of Coordinated Communication in Infants at Heightened Risk for Autism Spectrum Disorder.
abstract: This study evaluated the extent to which developmental change in coordination of social communication in early infancy differentiates children eventually diagnosed with ASD from those not likely to develop the disorder. A prospective longitudinal design was used to compare nine infants at heightened risk for ASD (HR) later diagnosed with ASD, to 13 HR infants with language delay, 28 HR infants with no diagnosis, and 30 low risk infants. Hierarchical linear modeling analyses revealed that ASD infants exhibited significantly slower growth in coordinations overall and in gestures coordinated with vocalizations, even relative to HR infants with language delay. Disruption in the development of gesture-vocalization coordinations may result in negative cascading effects that adversely impact later social and linguistic development.
authors.affiliation: Department of Psychology, Center for Autism and Related Disabilities, University of Miami, P.O. Box 248768, 5665 Ponce de Leon Boulevard, Coral Gables, Miami, FL, 33124-0725, USA, mparlade@miami.edu.
authors.forename: Meaghan V
authors.initials: MV
authors.lastname: Parladé
authors.forename: Jana M
authors.initials: JM
authors.lastname: Iverson
mesh_terms: D000067877:Autism Spectrum Disorder / Q000150:complications* / Q000523:psychology*; D016022:Case-Control Studies; D002675:Child, Preschool; D003142:Communication; D005260:Female; D005868:Gestures; D006801:Humans; D007223:Infant; D007805:Language Development Disorders / Q000150:complications* / Q000523:psychology*; D008137:Longitudinal Studies; D008297:Male; D011446:Prospective Studies; D012306:Risk