title: Simultaneous (18)F-FDOPA PET/CT-guided biopsy and radiofrequency ablation of recurrent neuroendocrine hepatic metastasis: further step toward a theranostic approach.
abstract: PET/CT-guided biopsy may be useful to confirm the metabolic findings when conventional imaging fails to show morphological abnormalities. Herein, we report the results of simultaneous F-FDOPA (fluorodihydroxyphenylalanine) PET/CT-guided biopsy and RFA (radiofrequency ablation) in 1 patient with hepatic metastatic evolution of a well-differentiated ileal neuroendocrine tumor. Beyond FDG, FDOPA could be successfully recommended in patients with neuroendocrine tumor for planning PET/CT-guided diagnostic biopsy, ablative treatment, and immediate efficacy assessment in a 1-step examination.
authors.affiliation: From the *Department of Biophysics and Nuclear Medicine, University Hospitals of Strasbourg; †ICube, University of Strasbourg/CNRS (UMR 7357) and FMTS, Faculty of Medicine; Departments of ‡Interventional Radiology, and §Visceral Surgery and Transplantation, University Hospitals of Strasbourg, Strasbourg, France.
authors.forename: Alessio
authors.initials: A
authors.lastname: Imperiale
authors.forename: Julien
authors.initials: J
authors.lastname: Garnon
authors.forename: Philippe
authors.initials: P
authors.lastname: Bachellier
authors.forename: Afshin
authors.initials: A
authors.lastname: Gangi
authors.forename: Izzie Jacques
authors.initials: IJ
authors.lastname: Namer
mesh_terms: D055011:Ablation Techniques; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives; D006801:Humans; D007078:Ileal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D061705:Image-Guided Biopsy; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary / Q000601:surgery; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D049268:Positron-Emission Tomography; D000078702:Radiofrequency Therapy; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; C043437:fluorodopa F 18; D004295:Dihydroxyphenylalanine