title: [Invasive pulmonary aspergillosis in influenza].
abstract: BACKGROUND
  Invasive pulmonary aspergillosis (IPA) is a life-threatening infection that occurs predominantly in severely immunocompromised patients. Recently, IPA is also increasingly seen in less severely immunocompromised patients, such as patients with COPD receiving glucocorticoids and patients on ventilation in an IC unit.
  
  
  METHODS
  Here we present the case of a 59-year-old male who died of influenza complicated by a superinfection with Aspergillus fumigatus. This patient had no known previous medical history, except schizophrenia.
  
  
  CONCLUSIONS
  Since the 2009 influenza pandemic, IPA has been increasingly reported as a superinfection in patients with a severe influenza virus infection. This combined Aspergillus and influenza infection often has a fatal outcome. An Aspergillus sputum culture should be taken seriously in patients with severe influenza pneumonia, and treatment should be considered early in the disease course.
authors.affiliation: Radboudumc, Nijmegen.
authors.forename: Eva
authors.initials: E
authors.lastname: Kolwijck
authors.forename: Henk
authors.initials: H
authors.lastname: Scheper
authors.forename: Judith
authors.initials: J
authors.lastname: Beuving
authors.forename: Ed J
authors.initials: EJ
authors.lastname: Kuijper
authors.forename: Johannes G
authors.initials: JG
authors.lastname: van der Hoeven
authors.forename: Paul E
authors.initials: PE
authors.lastname: Verweij
mesh_terms: D001232:Aspergillus fumigatus; D017809:Fatal Outcome; D006801:Humans; D007251:Influenza, Human / Q000150:complications* / Q000175:diagnosis; D055744:Invasive Pulmonary Aspergillosis / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D015163:Superinfection / Q000150:complications* / Q000175:diagnosis