title: Sinonasal angiosarcoma.
abstract: BACKGROUND
  Angiosarcoma is a malignant tumour arising from endothelial cells that accounts for 1% of all sarcomas. The sinonasal site of angiosarcoma is exceptional.
  
  
  METHODS
  The authors report a case of sinonasal angiosarcoma in a 53-year-old man. Despite wide resection by open surgery and postoperative chemoradiotherapy, several tumour recurrences were observed, requiring multiple operations.
  
  
  CONCLUSIONS
  Only histological examination with immunohistochemistry is able to confirm the diagnosis (factor VIII, CD34 and CD31 antigens). Standard treatment consists of surgery with wide resection followed by radiotherapy. The authors discuss the treatment modalities and prognosis of this tumour.
authors.affiliation: Service ORL et chirurgie cervico-faciale, Hôpital des Spécialités, CHU Rabat, Université Mohammed V, Avenue Abderrahim Bouabid, Rabat, Morocco. Electronic address: orl.farid@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: Es-Sbissi
authors.affiliation: Service ORL et chirurgie cervico-faciale, Hôpital des Spécialités, CHU Rabat, Université Mohammed V, Avenue Abderrahim Bouabid, Rabat, Morocco.
authors.forename: S
authors.initials: S
authors.lastname: Nitassi
authors.affiliation: Service ORL et chirurgie cervico-faciale, Hôpital des Spécialités, CHU Rabat, Université Mohammed V, Avenue Abderrahim Bouabid, Rabat, Morocco.
authors.forename: M
authors.initials: M
authors.lastname: Boulaadas
authors.affiliation: Service ORL et chirurgie cervico-faciale, Hôpital des Spécialités, CHU Rabat, Université Mohammed V, Avenue Abderrahim Bouabid, Rabat, Morocco.
authors.forename: L
authors.initials: L
authors.lastname: Essakalli
mesh_terms: D059248:Chemoradiotherapy / Q000379:methods; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005005:Ethmoid Sinus / Q000473:pathology*; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D057605:Natural Orifice Endoscopic Surgery / Q000379:methods; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000628:therapy; D009367:Neoplasm Staging; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis* / Q000628:therapy; D012307:Risk Factors; D014420:Turbinates / Q000473:pathology*
keywords: Angiosarcoma; Nasal; Radiotherapy; Sinus