title: Hepatocellular carcinoma among cirrhotics--utility of screening and surveillance programs--review article.
abstract: Screening of known cirrhotics for hepatocellular cancer (HCC) has long been a contentious topic. Studies to date have failed to conclusively prove or disprove the validity of α-fetoprotein (AFP) and hepatic ultrasound as screening mechanisms for HCC among cirrhotics. It is not clear whether these screening mechanisms provide any benefit in terms of reduced morbidity and mortality. Screening for HCC among cirrhotics by using AFP and/or imaging at every 6 months correlate with HCC diagnosis, thus portending better treatment options and an improved prognosis. Screening all the known cirrhotics for HCC may lead to decreased mortality.
authors.affiliation: "Floreasca" Clinical Emergency Hospital, Bucharest.
authors.forename: R
authors.initials: R
authors.lastname: Opriță
authors.affiliation: Department of Anatomy, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: I B
authors.initials: IB
authors.lastname: Diaconescu
authors.affiliation: Department of Anatomy, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: G
authors.initials: G
authors.lastname: Lupu
authors.affiliation: Department of Anatomy, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania ; "Floreasca" Clinical Emergency Hospital, Bucharest.
authors.forename: A
authors.initials: A
authors.lastname: Lupu
authors.affiliation: Department of Anatomy, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: B
authors.initials: B
authors.lastname: Cristea
authors.affiliation: "Floreasca" Clinical Emergency Hospital, Bucharest.
authors.forename: M R
authors.initials: MR
authors.lastname: Bratu
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000175:diagnosis*; D055088:Early Detection of Cancer; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000175:diagnosis*; D008113:Liver Neoplasms / Q000150:complications* / Q000175:diagnosis*; D011159:Population Surveillance
keywords: AFP; hepatocellular carcinoma; prognosis; screening