title: Implementing multiplicity editing in selective HSQMBC experiments.
abstract: Even C/CH(2) and odd CH/CH(3) carbon-multiplicity information can be directly distinguished from the relative positive/negative phase of cross-peaks in a novel ME (Multiplicity-Edited)-selHSQMBC experiment. The method can be extended by a TOCSY propagation step, and it is fully compatible for the simultaneous and precise determination of long-range heteronuclear coupling constants. Broadband homonuclear decoupling techniques can also be incorporated to enhance sensitivity and signal resolution by effective collapse of J(HH) multiplets.
authors.affiliation: Servei de Ressonància Magnètica Nuclear, Universitat Autònoma de Barcelona, Facultat de Ciències, E-08193 Bellaterra (Barcelona), Catalonia, Spain; NMR Structure Elucidation, Process and Analytical Chemistry, Merck & Co. Inc., 126 E. Lincoln Avenue, Rahway, NJ 07065, USA.
authors.forename: Josep
authors.initials: J
authors.lastname: Saurí
authors.affiliation: Servei de Ressonància Magnètica Nuclear, Universitat Autònoma de Barcelona, Facultat de Ciències, E-08193 Bellaterra (Barcelona), Catalonia, Spain.
authors.forename: Eduard
authors.initials: E
authors.lastname: Sistaré
authors.affiliation: NMR Structure Elucidation, Process and Analytical Chemistry, Merck & Co. Inc., 126 E. Lincoln Avenue, Rahway, NJ 07065, USA.
authors.forename: R
authors.initials: R
authors.lastname: Thomas Williamson
authors.affiliation: NMR Structure Elucidation, Process and Analytical Chemistry, Merck & Co. Inc., 126 E. Lincoln Avenue, Rahway, NJ 07065, USA.
authors.forename: Gary E
authors.initials: GE
authors.lastname: Martin
authors.affiliation: Servei de Ressonància Magnètica Nuclear, Universitat Autònoma de Barcelona, Facultat de Ciències, E-08193 Bellaterra (Barcelona), Catalonia, Spain. Electronic address: teodor.parella@uab.cat.
authors.forename: Teodor
authors.initials: T
authors.lastname: Parella
keywords: HOBS; HSQMBC; Heteronuclear coupling constants; IPAP; Multiplicity-editing