title: [Severe bradycardia in general anaesthesia in a patient treated with cholinesterase inhibitors for dementia].
abstract: Patients suffering from Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies can be treated well with the cholinesterase inhibitors rivastigmine or donepezil, and because of the increasing number of these patients undergoing surgery in general anaesthesia we find it urgent to draw attention to possible complications such as severe bradycardia or third-degree heart block when propofol and remifentanil are being used.
authors.affiliation: Finsensgade 35, 6700 Esbjerg. m.ersgaard@gmail.com.
authors.forename: Marlene Ersgaard
authors.initials: ME
authors.lastname: Jellinge
authors.forename: Alan Hamilton
authors.initials: AH
authors.lastname: Ferguson
mesh_terms: D000368:Aged; D000768:Anesthesia, General / Q000009:adverse effects; D018686:Anesthetics, Intravenous / Q000009:adverse effects; D001919:Bradycardia / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D002800:Cholinesterase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D003704:Dementia / Q000188:drug therapy; D000077265:Donepezil; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D006801:Humans; D007189:Indans / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D010880:Piperidines / Q000009:adverse effects* / Q000627:therapeutic use; D015742:Propofol / Q000009:adverse effects; D000077208:Remifentanil
chemical_list: D018686:Anesthetics, Intravenous; D002800:Cholinesterase Inhibitors; D007189:Indans; D010880:Piperidines; D000077265:Donepezil; D000077208:Remifentanil; D015742:Propofol