title: Photosensitive disorders of the skin with ocular involvement.
abstract: Patients with photosensitive disorders of the skin may present with ocular manifestations that are evident at birth or may be manifested later with progression of the disorder. Dermatologists should be able to recognize these and appropriately refer patients for further management. Ocular involvement associated with immunologically mediated photodermatoses, drug- and chemical-induced photosensitivity, photodermatoses associated with defective DNA repair/chromosome instability, and photoaggravated dermatoses are reviewed. Photodermatoses are commonly classified into four general groups: (1) immunologically mediated photodermatoses; (2) drug- and chemical-induced photosensitivity; (3) photodermatoses associated with defective DNA repair/chromosome instability; and (4) photoaggravated dermatoses. Photodermatoses in these groups with ocular involvement will be discussed. In addition, skin diseases associated with photophobia are also described.
authors.affiliation: Department of Dermatology, Henry Ford Hospital, 3031 West Grand Blvd, Suite 800, Detroit, MI 48202.
authors.forename: Pranita V
authors.initials: PV
authors.lastname: Rambhatla
authors.affiliation: Wayne State University School of Medicine, 540 E Canfield St, Detroit, MI 48201.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Brescoll
authors.affiliation: Department of Ophthalmology, Wayne State University School of Medicine, 4717 St. Antoine Detroit, MI 48201.
authors.forename: Frank
authors.initials: F
authors.lastname: Hwang
authors.affiliation: Department of Ophthalmology, Wayne State University School of Medicine, 4717 St. Antoine Detroit, MI 48201.
authors.forename: Mark
authors.initials: M
authors.lastname: Juzych
authors.affiliation: Department of Dermatology, Henry Ford Hospital, 3031 West Grand Blvd, Suite 800, Detroit, MI 48202. Electronic address: Hlim1@hfhs.org.
authors.forename: Henry W
authors.initials: HW
authors.lastname: Lim
mesh_terms: D015897:Comorbidity; D017454:Dermatitis, Photoallergic / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D017484:Dermatitis, Phototoxic / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D005128:Eye Diseases / Q000175:diagnosis* / Q000453:epidemiology* / Q000276:immunology / Q000628:therapy; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D010787:Photosensitivity Disorders / Q000175:diagnosis / Q000453:epidemiology; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index