title: Epidemiological study of cholesteatoma in Fukuoka City.
abstract: OBJECTIVE
  To investigate the pathogenesis of cholesteatoma, we planned to conduct a cohort study. As a first step, we conducted an epidemiological study in Fukuoka City, Japan to determine the incidence of cholesteatoma treated both with and without surgery. We also conducted a case-control study to investigate the pathogenesis of cholesteatoma.
  
  
  RESULTS
  The annual incidence of cholesteatoma, including cases treated without surgery, was 6.8-10.0 in a population of 100 000. The results of the case-control study suggested that a past history of otitis media and habitual sniffing caused by a patulous eustachian tube play a role in the pathogenesis of cholesteatoma.
  
  
  CONCLUSIONS
  The annual incidence of cholesteatoma, including cases treated without surgery, was considered to not be high enough to perform a cohort study. The results of the case-control study suggest that otitis media and habitual sniffing due to a patulous eustachian tube, contribute to the onset of cholesteatoma.
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: S
authors.initials: S
authors.lastname: Shibata
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: K
authors.initials: K
authors.lastname: Murakami
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Umeno
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: S
authors.initials: S
authors.lastname: Komune
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002781:Cholesteatoma / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D015331:Cohort Studies; D005064:Eustachian Tube; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010033:Otitis Media / Q000150:complications; D012307:Risk Factors
keywords: Eziology; Otitis Media with Effusion