title: Photodynamic inactivation of bacteria in vitro under the effect of blue light.
abstract: We studied the photodynamic inactivation of E. coli, S. aureus, and P. aeruginosa in vitro. Bacteria suspensions were incubated with riboflavin and exposed to blue light emitted by a diode matrix. Exogenous photosensitizer riboflavin efficiently inactivated bacteria, while methylene blue was ineffective. Under the effect of blue light in a dose of 117 J/cm(2), photoinactivation of E. coli, S. aureus, and P. aeruginosa occurred without photosensitizer riboflavin.
authors.affiliation: Moscow Research Institute of Pediatrics and Pediatric Surgery, Ministry of the Health of the Russian Federation, Moscow, Russia, ekeshishyan@list.ru.
authors.forename: E S
authors.initials: ES
authors.lastname: Keshishyan
authors.forename: Z V
authors.initials: ZV
authors.lastname: Zaporozhtseva
authors.forename: O M
authors.initials: OM
authors.lastname: Zenina
authors.forename: V S
authors.initials: VS
authors.lastname: Zrodnikov
mesh_terms: D001419:Bacteria / Q000187:drug effects / Q000528:radiation effects*; D015169:Colony Count, Microbial; D004307:Dose-Response Relationship, Radiation; D004926:Escherichia coli; D008027:Light; D010778:Photochemotherapy / Q000379:methods; D011550:Pseudomonas aeruginosa; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology / Q000532:radiotherapy*; D012256:Riboflavin / Q000494:pharmacology*; D013211:Staphylococcus aureus
chemical_list: D012256:Riboflavin