title: Cobalt-promoted dimerization of aminoquinoline benzamides.
abstract: A method for aminoquinoline-directed, cobalt-promoted dimerization of benzamides has been developed. Reactions proceed in ethanol solvent in the presence of Mn(OAc)2 cocatalyst and Na2CO3 base and use oxygen as a terminal oxidant. Bromo, iodo, nitro, ether, and ester moieties are compatible with the reaction conditions. Cross-coupling of electronically dissimilar aminoquinoline benzamides proceeds with modest yields and selectivities.
authors.affiliation: Department of Chemistry, University of Houston , Houston, Texas 77204-5003, United States.
authors.forename: Liene
authors.initials: L
authors.lastname: Grigorjeva
authors.forename: Olafs
authors.initials: O
authors.lastname: Daugulis
mesh_terms: D000634:Aminoquinolines / Q000737:chemistry*; D001549:Benzamides / Q000737:chemistry*; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D019281:Dimerization; D015394:Molecular Structure
chemical_list: D000634:Aminoquinolines; D001549:Benzamides; D003035:Cobalt; C037689:benzamide