title: Dihydroquercetin effects on the morphology and antioxidant/prooxidant balance of the prostate in rats with sulpiride-induced benign hyperplasia.
abstract: A course of dihydroquercetin (antioxidant) injections to 5-month-old Wistar rats with sulpiride-induced benign prostatic hyperplasia led to reduction of proliferative activity in the glandular structures and to attenuation of the inflammatory reaction in the tissue. Prostatic antioxidant/prooxidant balance returned to normal after the treatment.
authors.affiliation: E. D. Goldberg Research Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia, reprofarm@yandex.ru.
authors.forename: T G
authors.initials: TG
authors.lastname: Borovskaya
authors.forename: N A
authors.initials: NA
authors.lastname: Krivova
authors.forename: O B
authors.initials: OB
authors.lastname: Zaeva
authors.forename: T I
authors.initials: TI
authors.lastname: Fomina
authors.forename: S I
authors.initials: SI
authors.lastname: Kamalova
authors.forename: M E
authors.initials: ME
authors.lastname: Poluektova
authors.forename: A V
authors.initials: AV
authors.lastname: Vychuzhanina
authors.forename: Yu A
authors.initials: YA
authors.lastname: Shchemerova
authors.forename: V A
authors.initials: VA
authors.lastname: Grigor'eva
authors.forename: V E
authors.initials: VE
authors.lastname: Goldberg
authors.forename: M B
authors.initials: MB
authors.lastname: Plotnikov
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D006652:Histological Techniques; D008297:Male; D011470:Prostatic Hyperplasia / Q000139:chemically induced* / Q000188:drug therapy* / Q000473:pathology*; D011794:Quercetin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D017382:Reactive Oxygen Species / Q000378:metabolism*; D018709:Statistics, Nonparametric; D013469:Sulpiride / Q000009:adverse effects*
chemical_list: D000975:Antioxidants; D017382:Reactive Oxygen Species; D013469:Sulpiride; D011794:Quercetin; C003377:taxifolin