title: Robustness of synthetic circadian clocks to multiple environmental changes.
abstract: A molecular network that mimics circadian clocks from cyanobacteria is constructed in silico. Simulating its oscillatory behaviour under variable conditions reveals its robustness relative to networks of alternative topologies. The principles for synthetic chemical circadian networks to work properly are consequently highlighted.
authors.affiliation: Department of Chemistry, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel. gonenash@bgu.ac.il.
authors.forename: Lilia
authors.initials: L
authors.lastname: Gurevich
authors.forename: Rivka
authors.initials: R
authors.lastname: Cohen-Luria
authors.forename: Nathaniel
authors.initials: N
authors.lastname: Wagner
authors.forename: Gonen
authors.initials: G
authors.lastname: Ashkenasy
mesh_terms: D057906:Circadian Clocks; D003198:Computer Simulation; D000458:Cyanobacteria / Q000378:metabolism*; D007700:Kinetics