title: Correlation between gastric transit time measured by video capsule endoscopy and gastric emptying determined by the continuous real-time 13C breath test (BreathID system).
abstract: OBJECTIVE
  The aim of this study was to determine the possible existence of a correlation between the gastric transit time (GTT) measured by video capsule endoscopy (VCE) and the parameters of gastric emptying determined using 13C breath test (BreathID system).
  
  
  METHODS
  Eight healthy male volunteers participated in this randomized, two-way crossover study. The subjects were randomly assigned to undergo VCE using the PillCam SB capsule endoscopy system or the 13C breath test for 4 hours after a test meal (400 kcal per 400 mL) containing 100 mg of 13C acetic acid administered after overnight fasting. The VCE images were analyzed and the GTT was determined using the proprietary RAPID software. The parameters, namely T lag, T 1/2 and GEC were calculated using the Oridion Research Software (β version). The GTT measured by VCE and the parameters of gastric emptying were compared statistically.
  
  
  RESULTS
  No significant correlation was observed between the GTT and T lag (p = 0.5263), T 1/2 (p = 0.4100) or GEC (p = 0.2410), as determined by calculation of the Spearman’s rank correlation coefficient.
  
  
  CONCLUSIONS
  GTT measured by VCE cannot serve as asubstitute for the gastric emptying time measured bythe 13C breath test.
authors.forename: Takashi
authors.initials: T
authors.lastname: Nonaka
authors.forename: Masahiko
authors.initials: M
authors.lastname: Inamori
authors.forename: Hiroki
authors.initials: H
authors.lastname: Endo
authors.forename: Mizue
authors.initials: M
authors.lastname: Matsuura
authors.forename: Shiori
authors.initials: S
authors.lastname: Uchiyama
authors.forename: Eiji
authors.initials: E
authors.lastname: Yamada
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Sekino
authors.forename: Eiji
authors.initials: E
authors.lastname: Sakai
authors.forename: Takuma
authors.initials: T
authors.lastname: Higurashi
authors.forename: Hidenori
authors.initials: H
authors.lastname: Ohkubo
authors.forename: Keiko
authors.initials: K
authors.lastname: Akimoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Iida
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Takahashi
authors.forename: Tomoko
authors.initials: T
authors.lastname: Koide
authors.forename: Wataru
authors.initials: W
authors.lastname: Shibata
authors.forename: Tomonori
authors.initials: T
authors.lastname: Ida
authors.forename: Akihiko
authors.initials: A
authors.lastname: Kusakabe
authors.forename: Eiji
authors.initials: E
authors.lastname: Gotoh
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nakajima
authors.forename: Shin
authors.initials: S
authors.lastname: Maeda
mesh_terms: D019342:Acetic Acid; D000328:Adult; D001944:Breath Tests / Q000295:instrumentation; D053704:Capsule Endoscopy; D002247:Carbon Isotopes; D018592:Cross-Over Studies; D004867:Equipment Design; D005746:Gastric Emptying; D005772:Gastrointestinal Transit; D006801:Humans; D007564:Japan; D008297:Male; D019518:Postprandial Period; D011237:Predictive Value of Tests; D013997:Time Factors; D014741:Video Recording; D055815:Young Adult
chemical_list: D002247:Carbon Isotopes; D019342:Acetic Acid