title: Delayed-onset postoperative endophthalmitis secondary to Exophiala.
abstract: Exophiala is a genus of slow-growing, melanin-producing, saprophytic fungi most commonly found in soil, faeces and decaying plant matter. It is an unusual fungal pathogen capable of causing a variety of ophthalmic manifestations, including keratitis, scleritis and endophthalmitis. In this report, we present a rare case of delayed-onset postoperative endophthalmitis confined to the anterior segment, secondary to Exophiala species. Previous reported cases of delayed-onset postoperative endophthalmitis have been treated medically, with suboptimal outcomes. Our experience supports the use of anterior segment surgery to clear the nidus of disease combined with intravitreal voriconazole to prevent recurrence of the infection.
authors.affiliation: University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
authors.forename: Jose Alberto
authors.initials: JA
authors.lastname: Quintero-Estades
authors.affiliation: Bascom Palmer Eye Institute, Miami, Florida, USA.
authors.forename: Scott
authors.initials: S
authors.lastname: Walter
authors.affiliation: Bascom Palmer Eye Institute, Miami, Florida, USA.
authors.forename: Felipe
authors.initials: F
authors.lastname: Valenzuela
authors.affiliation: Bascom Palmer Eye Institute, Miami, Florida, USA.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Amescua
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D005093:Exophiala / Q000302:isolation & purification*; D015821:Eye Infections, Fungal / Q000188:drug therapy*; D005260:Female; D006801:Humans; D060446:Phaeohyphomycosis / Q000175:diagnosis* / Q000188:drug therapy*; D011183:Postoperative Complications / Q000188:drug therapy* / Q000382:microbiology*; D014821:Vitrectomy; D065819:Voriconazole / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D065819:Voriconazole