title: Enteric hyperoxaluria: an important cause of end-stage kidney disease.
abstract: Hyperoxaluria is a frequent complication of inflammatory bowel diseases, ileal resection and Roux-en-Y gastric bypass and is well-known to cause nephrolithiasis and nephrocalcinosis. The associated prevalence of chronic kidney disease and end-stage kidney disease (ESKD) is less clear but may be more consequential than recognized. In this review, we highlight three cases of ESKD due to enteric hyperoxaluria following small bowel resections. We review current information on the pathophysiology, complications and treatment of this complex disease.
authors.affiliation: Nephrology Section, New York Harbor VA Healthcare System and Nephrology Division, NYU Langone Medical Center, New York, NY, USA.
authors.forename: Lama
authors.initials: L
authors.lastname: Nazzal
authors.affiliation: Nephrology Section, New York Harbor VA Healthcare System and Nephrology Division, NYU Langone Medical Center, New York, NY, USA.
authors.forename: Sonika
authors.initials: S
authors.lastname: Puri
authors.affiliation: Nephrology Section, New York Harbor VA Healthcare System and Nephrology Division, NYU Langone Medical Center, New York, NY, USA.
authors.forename: David S
authors.initials: DS
authors.lastname: Goldfarb
mesh_terms: D006801:Humans; D006959:Hyperoxaluria / Q000150:complications*; D007676:Kidney Failure, Chronic / Q000209:etiology*; D052878:Urolithiasis / Q000150:complications*
keywords: inflammatory bowel disease; kidney stones; oxalate; transplantation; urolithiasis