title: Evaluation of intrabony defects treated with platelet-rich fibrin or autogenous bone graft: A comparative analysis.
abstract: OBJECTIVE
  The primary objective of this study was to compare clinically and radiographically the efficacy of autologous platelet rich fibrin (PRF) and autogenous bone graft (ABG) obtained using bone scrapper in the treatment of intrabony periodontal defects.
  
  
  METHODS
  Thirty-eight intrabony defects (IBDs) were treated with either open flap debridement (OFD) with PRF or OFD with ABG. Clinical parameters were recorded at baseline and 6 months postoperatively. The defect-fill and defect resolution at baseline and 6 months were calculated radiographically (intraoral periapical radiographs [IOPA] and orthopantomogram [OPG]).
  
  
  RESULTS
  Significant probing pocket depth (PPD) reduction, clinical attachment level (CAL) gain, defect fill and defect resolution at both PRF and ABG treated sites with OFD was observed. However, inter-group comparison was non-significant (P > 0.05). The bivariate correlation results revealed that any of the two radiographic techniques (IOPA and OPG) can be used for analysis of the regenerative therapy in IBDs.
  
  
  CONCLUSIONS
  The use of either PRF or ABG were effective in the treatment of three wall IBDs with an uneventful healing of the sites.
authors.affiliation: Department of Periodontology, Saraswati Dental College, Lucknow, Uttar Pradesh, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Mathur
authors.affiliation: Department of Periodontology, Saraswati Dental College, Lucknow, Uttar Pradesh, India.
authors.forename: Vivek Kumar
authors.initials: VK
authors.lastname: Bains
authors.affiliation: Rama Dental College Hospital and Research Centre, Kanpur, Uttar Pradesh, India.
authors.forename: Vivek
authors.initials: V
authors.lastname: Gupta
authors.affiliation: Department of Periodontology, Saraswati Dental College, Lucknow, Uttar Pradesh, India.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Jhingran
authors.affiliation: Department of Periodontology, Saraswati Dental College, Lucknow, Uttar Pradesh, India.
authors.forename: G P
authors.initials: GP
authors.lastname: Singh
keywords: Autogenous bone graft; blood platelets; chronic periodontitis; wound healing