title: Mini-incision cataract surgery and toric lens implantation for the reduction of high myopic astigmatism in patients with pellucid marginal degeneration.
abstract: OBJECTIVE
  To evaluate the clinical outcomes, safety, and efficacy of cataract surgery with the implantation of a toric intraocular lens (IOL) in eyes with stable pellucid marginal degeneration (PMD).
  
  
  METHODS
  Eleven eyes (eight patients) diagnosed as stable PMD and cataract underwent mini-incision 2.2 mm cataract surgery followed by the implantation of hydrophobic toric aspheric IOL (AcrySof IQ Toric IOL, Alcon, Fort Worth, TX, USA). Perioperative variables of interest included uncorrected (UDVA) and corrected (CDVA) distance visual acuities, manifest refraction, and corneal topography. Paired samples t-tests were used to analyze preoperative and postoperative visual acuity, astigmatism, and spherical equivalent (SE) parameters. Follow-up was 6 months.
  
  
  RESULTS
  The mean CDVA was 0.62±0.26 logMAR preoperatively and 0.07±0.07 logMAR postoperatively. The mean preoperative sphere and cylinder was -3.14±3.58D and -4.84±2.02D, respectively. The mean postoperative manifest refractive sphere and cylinder was -0.30±0.51D and -0.81±1.51D, respectively. There was a significant reduction in refractive astigmatism after toric IOL implantation (P<0.002). The toric IOL axis rotation was <5° in all cases at the final follow-up.
  
  
  CONCLUSIONS
  Implantation of hydrophobic toric IOL was a safe and effective surgical procedure to correct mild to moderate stable PMD.
authors.affiliation: Ophthalmology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Balestrazzi
authors.affiliation: Ophthalmology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Baiocchi
authors.affiliation: Department of Medicine, Surgery and Neuroscience, Ophthalmic Hospital, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Balestrazzi
authors.affiliation: Ophthalmology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Cartocci
authors.affiliation: Ophthalmology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
authors.forename: G M
authors.initials: GM
authors.lastname: Tosi
authors.affiliation: Ophthalmology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Martone
authors.affiliation: Department of Medicine, Surgery and Neuroscience, Ophthalmic Hospital, Rome, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Michieletto
mesh_terms: D000368:Aged; D001251:Astigmatism / Q000503:physiopathology / Q000601:surgery*; D002386:Cataract / Q000150:complications*; D003315:Cornea / Q000503:physiopathology; D003317:Corneal Dystrophies, Hereditary / Q000150:complications*; D019781:Corneal Topography; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008866:Microsurgery; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D018918:Phacoemulsification; D011446:Prospective Studies; D011474:Prosthesis Design; D012029:Refraction, Ocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology