title: Contralateral risk-reducing mastectomy: review of risk factors and risk-reducing strategies.
abstract: Rates of contralateral risk-reducing mastectomy have increased substantially over the last decade. Surgical oncologists are often in the frontline, dealing with requests for this procedure. This paper reviews the current evidence base regarding contralateral breast cancer, assesses the various risk-reducing strategies, and evaluates the cost-effectiveness of contralateral risk-reducing mastectomy.
authors.affiliation: Nightingale and Genesis Prevention Centre, University Hospital South Manchester, Southmoor Road, Manchester M23 9LT, UK ; Department of Breast Surgery, Queen Elizabeth Hospital, Birmingham B15 2TH, UK.
authors.forename: N N
authors.initials: NN
authors.lastname: Basu
authors.affiliation: Nightingale and Genesis Prevention Centre, University Hospital South Manchester, Southmoor Road, Manchester M23 9LT, UK.
authors.forename: L
authors.initials: L
authors.lastname: Barr
authors.affiliation: The Institute of Cancer Sciences, The University of Manchester, Oxford Road, Manchester M13 9PL, UK.
authors.forename: G L
authors.initials: GL
authors.lastname: Ross
authors.affiliation: Nightingale and Genesis Prevention Centre, University Hospital South Manchester, Southmoor Road, Manchester M23 9LT, UK ; University of Manchester Department of Genomic Medicine, Institute of Human Development, St. Mary's Hospital, Oxford Road, Manchester M13 9WL, UK.
authors.forename: D G
authors.initials: DG
authors.lastname: Evans
mesh_terms: D001943:Breast Neoplasms / Q000191:economics / Q000209:etiology / Q000517:prevention & control*; D003362:Cost-Benefit Analysis; D005260:Female; D006801:Humans; D008408:Mastectomy; D016609:Neoplasms, Second Primary / Q000191:economics / Q000209:etiology / Q000517:prevention & control*; D012307:Risk Factors; D006113:United Kingdom; D014481:United States