title: Clinical correlates of common corneal neovascular diseases: a literature review.
abstract: A large subset of corneal pathologies involves the formation of new blood and lymph vessels (neovascularization), leading to compromised visual acuity. This article aims to review the clinical causes and presentations of corneal neovascularization (CNV) by examining the mechanisms behind common CNV-related corneal pathologies, with a particular focus on herpes simplex stromal keratitis, contact lenses-induced keratitis and CNV secondary to keratoplasty. Moreover, we reviewed CNV in the context of different types of corneal transplantation and keratoprosthesis, and summarized the most relevant treatments available so far.
authors.affiliation: Doheny Image Reading Center, Doheny Eye Institute, University of California, Los Angeles, 1355 San Pablo Street, Los Angeles, California 90033, USA.
authors.forename: Nizar Saleh
authors.initials: NS
authors.lastname: Abdelfattah
authors.affiliation: Faculty of Medicine, Cairo University, Cairo 11956, Egypt.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Amgad
authors.affiliation: Department of Surgery, Mayo Clinic, Rochester 55905, MN, USA.
authors.forename: Amira A
authors.initials: AA
authors.lastname: Zayed
authors.affiliation: Faculty of Medicine, University of Alexandria, Alexandria 21131, Egypt.
authors.forename: Hamdy
authors.initials: H
authors.lastname: Salem
authors.affiliation: Department of Medical Oncology, Mayo Clinic, Rochester 55905, MN, USA.
authors.forename: Ahmed E
authors.initials: AE
authors.lastname: Elkhanany
authors.affiliation: Faculty of Oral and Dental Medicine, Cairo University, Cairo 11956, Egypt.
authors.forename: Heba
authors.initials: H
authors.lastname: Hussein
authors.affiliation: Antibody Laboratory, Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications, Alexandria 21934, Egypt.
authors.forename: Nawal
authors.initials: N
authors.lastname: Abd El-Baky
keywords: contact lens; cornea; herpes simplex keratitis; keratoplasty; keratoprosthesis; neovascularization