title: Recent advances of histone modification in gastric cancer.
abstract: Epigenetics play important roles during development progress of tumor. The histone modifications are the most important constituted field. Recently, accumulating research focused on exploring the roles of those modifications in regulating tumorigenesis. Moreover, the dysregulation of histone modifications is supposed to have vital clinical significance. Numerous histone modifications have the potential to be prognostic biomarkers, monitoring response of therapy, early diagnostic markers. Herein, we review the recent advances of histone modifications involving development of gastric cancer.
authors.forename: Wen-Yan
authors.initials: WY
authors.lastname: Yang
authors.forename: Jing-Liang
authors.initials: JL
authors.lastname: Gu
authors.affiliation: Key Laboratory of Medical Library, Shandong Institute of Medicine and Health Information, Shandong Academy of Medical Sciences, No. 18877 Jingshi Road, Jinan 250062, China.
authors.forename: Tian-Min
authors.initials: TM
authors.lastname: Zhen
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000235:genetics*; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D044127:Epigenesis, Genetic / Q000235:genetics*; D006657:Histones / Q000235:genetics*; D006801:Humans; D013274:Stomach Neoplasms / Q000235:genetics*
chemical_list: D014408:Biomarkers, Tumor; D006657:Histones