title: A multiscale decomposition approach to detect abnormal vasculature in the optic disc.
abstract: This paper presents a multiscale method to detect neovascularization in the optic disc (NVD) using fundus images. Our method is applied to a manually selected region of interest (ROI) containing the optic disc. All the vessels in the ROI are segmented by adaptively combining contrast enhancement methods with a vessel segmentation technique. Textural features extracted using multiscale amplitude-modulation frequency-modulation, morphological granulometry, and fractal dimension are used. A linear SVM is used to perform the classification, which is tested by means of 10-fold cross-validation. The performance is evaluated using 300 images achieving an AUC of 0.93 with maximum accuracy of 88%.
authors.affiliation: Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, NM, USA; VisionQuest Biomedical LLC, Albuquerque, NM, USA. Electronic address: capaagri@gmail.com.
authors.forename: Carla
authors.initials: C
authors.lastname: Agurto
authors.affiliation: VisionQuest Biomedical LLC, Albuquerque, NM, USA.
authors.forename: Honggang
authors.initials: H
authors.lastname: Yu
authors.affiliation: Universidad de Ingenieria y Tecnologia, Lima, Peru.
authors.forename: Victor
authors.initials: V
authors.lastname: Murray
authors.affiliation: Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, NM, USA.
authors.forename: Marios S
authors.initials: MS
authors.lastname: Pattichis
authors.affiliation: VisionQuest Biomedical LLC, Albuquerque, NM, USA.
authors.forename: Sheila
authors.initials: S
authors.lastname: Nemeth
authors.affiliation: VisionQuest Biomedical LLC, Albuquerque, NM, USA.
authors.forename: Simon
authors.initials: S
authors.lastname: Barriga
authors.affiliation: VisionQuest Biomedical LLC, Albuquerque, NM, USA.
authors.forename: Peter
authors.initials: P
authors.lastname: Soliz
mesh_terms: D003930:Diabetic Retinopathy / Q000473:pathology*; D017709:Fractals; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D009389:Neovascularization, Pathologic / Q000473:pathology*; D009898:Optic Disk / Q000098:blood supply* / Q000473:pathology*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D042262:Retinoscopy / Q000379:methods*; D012680:Sensitivity and Specificity
keywords: Amplitude-modulation frequency-modulation; Diabetic retinopathy; Fractal dimension; Granulometry; Neovascularization