title: Copper-catalyzed [3 + 2] cycloaddition/oxidation reactions between nitro-olefins and organic azides: highly regioselective synthesis of NO2-substituted 1,2,3-triazoles.
abstract: A new copper-catalyzed [3 + 2] cycloaddition/oxidation reaction of nitro-olefins with organic azides has been developed to afford 1,4(-NO2),5-trisubstituted 1,2,3-triazoles. This reaction sequence has a broad substrate scope and affords NO2-substituted 1,2,3-triazoles with high regioselectivities and in good to excellent yields. The involved oxidative process overcomes the elimination of HNO2 for general cycloaddition of nitro-olefins with organic azides, which shows a high atom economy and potential applications.
authors.affiliation: School of Chemistry and Environmental Engineering, Wuhan Institute of Technology , Wuhan 430073, China.
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Chen
authors.forename: Gang
authors.initials: G
authors.lastname: Nie
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhang
authors.forename: Shan
authors.initials: S
authors.lastname: Ma
authors.forename: Huan
authors.initials: H
authors.lastname: Li
authors.forename: Qinquan
authors.initials: Q
authors.lastname: Hu