title: Patients with eating disorders showed no signs of coeliac disease before and after nutritional intervention.
abstract: OBJECTIVE
  This study assessed the presence of specific antibodies for coeliac disease in outpatients suffering from eating disorders before and after nutritional intervention. We also evaluated whether those patients should undergo regular screening for coeliac disease.
  
  
  METHODS
  The sample consisted of 154 patients with a mean age of 16.7 years - ranging from one to 19 years of age - suffering from eating disorders. Serology screening for coeliac disease and total immunoglobulin A (IgA) levels was evaluated in the 154 children before the nutritional intervention and in 104 patients after the intervention. The patients consumed an adequate amount of gluten in both phases.
  
  
  RESULTS
  Postintervention evaluation revealed that 92 patients (88.5%) achieved a normal body weight, while the remaining 12 (11.5%) became obese. Postprandial abdominal discomfort and pain were resolved. The serology tests were negative in all patients, before and after intervention. None displayed IgA deficiency.
  
  
  CONCLUSIONS
  To the best of our knowledge, this was the first prospective study where patients underwent a screening serology for coeliac disease before and after nutritional intervention. No indication of the coexistence of eating disorders and coeliac disease was documented, and the patients in our study were unlikely to require regular screening for coeliac disease.
authors.affiliation: Second Department of Pediatrics, 'P & A Kyriakou' Children's Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Maria
authors.initials: M
authors.lastname: Kaltsa
authors.affiliation: Second Department of Pediatrics, 'P & A Kyriakou' Children's Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Anastasia
authors.initials: A
authors.lastname: Garoufi
authors.affiliation: Scientific Supervisor of Adolescent Health Unit, Second Department of Pediatrics, 'P& A Kyriakou' Children's Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Artemis
authors.initials: A
authors.lastname: Tsitsika
authors.affiliation: Department of Immunology and Histocompatibility, 'Evangelismos' General Hospital, Athens, Greece.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Tsirogianni
authors.affiliation: Department of Immunology and Histocompatibility, 'Evangelismos' General Hospital, Athens, Greece.
authors.forename: Chryssa
authors.initials: C
authors.lastname: Papasteriades
authors.affiliation: Second Department of Pediatrics, 'P & A Kyriakou' Children's Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Lydia
authors.initials: L
authors.lastname: Kossiva
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D002446:Celiac Disease / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D001068:Feeding and Eating Disorders / Q000097:blood / Q000150:complications* / Q000628:therapy*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007223:Infant; D008297:Male; D011446:Prospective Studies; D015430:Weight Gain; D055815:Young Adult
chemical_list: D007070:Immunoglobulin A
keywords: Adolescence; Childhood; Coeliac disease; Eating disorders