title: Low-grade fibromyxoid sarcoma of the sigmoid colon.
abstract: Low-grade fibromyxoid sarcoma (LGFMS) is a rare soft tissue tumor with a slight male predominance. The tumor has a tendency to arise from deep soft tissue of the trunk and lower extremities. Rare cases are reported to arise from the mediastinal and retroperitoneal areas. Its deceptively bland histologic appearance makes this tumor difficult to diagnose. Also, there are several histologic mimics that may hinder in its diagnosis. We report a case of low-grade fibromyxoid sarcoma from a 48-year-old woman, first documented herein to arise from the sigmoid. We also report the value of CD99, BCL2 and MUC4 stains in the diagnosis of this tumor.
authors.affiliation: Harbor-UCLA Medical Center, Department of Pathology. Electronic address: asmendoza@yahoo.com.
authors.forename: Alejandro S
authors.initials: AS
authors.lastname: Mendoza
authors.affiliation: Harbor-UCLA Medical Center, Department of Surgery.
authors.forename: Michael P
authors.initials: MP
authors.lastname: O'Leary
authors.affiliation: Harbor-UCLA Medical Center, Department of Pathology.
authors.forename: Shi-Kaung
authors.initials: SK
authors.lastname: Peng
authors.affiliation: Harbor-UCLA Medical Center, Department of Surgery.
authors.forename: Beverley A
authors.initials: BA
authors.lastname: Petrie
authors.affiliation: Harbor-UCLA Medical Center, Department of Surgery.
authors.forename: Andrew I
authors.initials: AI
authors.lastname: Li
authors.affiliation: Harbor-UCLA Medical Center, Department of Pathology.
authors.forename: Samuel W
authors.initials: SW
authors.lastname: French
mesh_terms: D000071443:12E7 Antigen; D015703:Antigens, CD / Q000032:analysis; D015815:Cell Adhesion Molecules / Q000032:analysis; D012809:Colon, Sigmoid / Q000473:pathology / Q000601:surgery; D005260:Female; D005350:Fibroma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D055264:Mucin-4 / Q000032:analysis; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000032:analysis; D011859:Radiography; D012811:Sigmoid Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D013194:Staining and Labeling
chemical_list: D000071443:12E7 Antigen; D015703:Antigens, CD; C061828:CD99 protein, human; D015815:Cell Adhesion Molecules; C524658:MUC4 protein, human; D055264:Mucin-4; D019253:Proto-Oncogene Proteins c-bcl-2
keywords: BCL2; CD99; Low-grade fibromyxoid sarcoma; MUC4; Sigmoid