title: PLLA nanofibrous paper-based plasmonic substrate with tailored hydrophilicity for focusing SERS detection.
abstract: We report a new paper-based surface enhanced Raman scattering (SERS) substrate platform contributed by a poly(l-lactic acid) (PLLA) nanofibrous paper adsorbed with plasmonic nanostructures, which can circumvent many challenges of the existing SERS substrates. This PLLA nanofibrous paper has three-dimensional porous structure, extremely clean surface with good hydrophobicity (contact angle is as high as 133.4°), and negligible background interference under Raman laser excitation. Due to the strong electrostatic interaction between PLLA nanofiber and cetyltrimethylammonium bromide (CTAB) molecules, the CTAB-coated gold nanorods (GNRs) are efficiently immobilized onto the fibers. Such a hydrophobic paper substrate with locally hydrophilic SERS-active area can confine analyte molecules and prevent the random spreading of molecules. The confinement leads to focusing effect and the GNRs-PLLA SERS substrate is found to be highly sensitive (0.1 nM Rhodamine 6G and malachite green) and exhibit excellent reproducibility (∼8% relative standard deviation (RSD)) and long-term stability. Furthermore, it is also cost-efficient, with simple fabrication methodology, and demonstrates high sample collection efficiency. All of these benefits ensure that this GNRs-PLLA substrate is a really perfect choice for a variety of SERS applications.
authors.affiliation: SZU-NUS Collaborative Innovation Center for Optoelectronic Science and Technology, and Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University , Shenzhen 518060, P.R. China.
authors.forename: Jundong
authors.initials: J
authors.lastname: Shao
authors.forename: Liping
authors.initials: L
authors.lastname: Tong
authors.forename: Siying
authors.initials: S
authors.lastname: Tang
authors.forename: Zhinan
authors.initials: Z
authors.lastname: Guo
authors.forename: Han
authors.initials: H
authors.lastname: Zhang
authors.forename: Penghui
authors.initials: P
authors.lastname: Li
authors.forename: Huaiyu
authors.initials: H
authors.lastname: Wang
authors.forename: Chang
authors.initials: C
authors.lastname: Du
authors.forename: Xue-Feng
authors.initials: XF
authors.lastname: Yu
mesh_terms: D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry; D006046:Gold / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D019344:Lactic Acid / Q000737:chemistry*; D057139:Nanofibers / Q000737:chemistry* / Q000648:ultrastructure; D043942:Nanotubes / Q000737:chemistry; D010209:Paper; D011091:Polyesters; D011108:Polymers / Q000737:chemistry*; D016062:Porosity; D012235:Rhodamines / Q000032:analysis*; D012394:Rosaniline Dyes / Q000032:analysis*; D013059:Spectrum Analysis, Raman; D055672:Static Electricity
chemical_list: D002593:Cetrimonium Compounds; D011091:Polyesters; D011108:Polymers; D012235:Rhodamines; D012394:Rosaniline Dyes; C026188:rhodamine 6G; C005095:malachite green; D019344:Lactic Acid; C033616:poly(lactide); D006046:Gold; D000077286:Cetrimonium
keywords: PLLA nanofibrous paper; gold nanorods; hydrophobic; plasmonic; surface-enhanced Raman spectroscopy