title: Crystal structure of 1,7,8,9-tetra-chloro-4-(3,5-di-chloro-benz-yl)-10,10-dimeth-oxy-4-aza-tri-cyclo-[5.2.1.0(2,6)]dec-8-ene-3,5-dione.
abstract: In the title compound, C17H11Cl6NO4, the configuration of the cyclo-alkene skeleton is endo,cis. The benzene ring is twisted by 58.94 (8)° from the attached pyrrolidine ring. Two carbonyl groups play a key role in the crystal packing. A short inter-molecular C⋯O distance of 3.017 (3) Å reveals that one carbonyl group is involved in dipole-dipole inter-actions, which link two adjacent enanti-omers into an inversion dimer. Another carbonyl group provides an acceptor for the weak inter-molecular C-H⋯O hydrogen bonds which link these dimers into layers parallel to (011).
authors.affiliation: Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, People's Republic of China.
authors.forename: He
authors.initials: H
authors.lastname: Liu
authors.affiliation: Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, People's Republic of China.
authors.forename: Jia-Liang
authors.initials: JL
authors.lastname: Zhong
authors.affiliation: Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, People's Republic of China.
authors.forename: Wen-Xia
authors.initials: WX
authors.lastname: Sun
authors.affiliation: State Key Laboratory of Bio-Organic & Natural Products Chmemistry, Shanghai Institute of Organic Chemistry, CAS., Shanghai 200032, People's Republic of China.
authors.forename: Yan-Qing
authors.initials: YQ
authors.lastname: Gong
authors.affiliation: Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, People's Republic of China.
authors.forename: Li-Hong
authors.initials: LH
authors.lastname: Liu
keywords: biological activity; crystal structure; cyclo­alkene skeleton; dipole–dipole inter­actions; hydrogen bonding; tri­cyclo­[5.2.1.02,6]dec-8-ene-3,5-dione