title: A colorimetric lead (II) ions sensor based on selective recognition of G-quadruplexes by a clip-like cyanine dye.
abstract: A probe for colorimetric detecting lead ion (Pb(2+)) has been designed by using a newly synthesized clip-like cyanine dye and G-quadruplex. The unique structure of the clip-like cyanine dye endowed the probe with a high selectivity towards Pb(2+). Significant changes in absorption spectra of the cyanine dye recognizing the Pb(2+)-induced conformational transition of G-quadruplexes made the probe show a high sensitivity towards Pb(2+) with a detection limit of 1nM. The excellent performance enabled the probe to be practically applied in measuring the Pb(2+) pollution in freshwater system.
authors.affiliation: National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China. Electronic address: hongxsun@iccas.ac.cn.
authors.forename: Hongxia
authors.initials: H
authors.lastname: Sun
authors.affiliation: National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China; Graduate University of the Chinese Academy of Sciences, Yuquan Road 19(A), Shijingshan District, Beijing 100049, PR China.
authors.forename: Lijia
authors.initials: L
authors.lastname: Yu
authors.affiliation: National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China; College of Chemistry Engineering, Hebei United University, Tangshan, Hebei 063009, PR China.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Chen
authors.affiliation: National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China.
authors.forename: Junfeng
authors.initials: J
authors.lastname: Xiang
authors.affiliation: College of Chemistry Engineering, Hebei United University, Tangshan, Hebei 063009, PR China.
authors.forename: Xiufeng
authors.initials: X
authors.lastname: Zhang
authors.affiliation: National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China; Graduate University of the Chinese Academy of Sciences, Yuquan Road 19(A), Shijingshan District, Beijing 100049, PR China.
authors.forename: Yunhua
authors.initials: Y
authors.lastname: Shi
authors.affiliation: National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China.
authors.forename: Qianfan
authors.initials: Q
authors.lastname: Yang
authors.affiliation: National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China.
authors.forename: Aijiao
authors.initials: A
authors.lastname: Guan
authors.affiliation: National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.affiliation: National Laboratory for Molecular Sciences, Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China. Electronic address: tangyl@iccas.ac.cn.
authors.forename: Yalin
authors.initials: Y
authors.lastname: Tang
mesh_terms: D003124:Colorimetry; D004396:Coloring Agents / Q000737:chemistry*; D054856:G-Quadruplexes; D007854:Lead / Q000032:analysis*
chemical_list: D004396:Coloring Agents; D007854:Lead
keywords: A clip-like cyanine dye; Colorimetric detection; G-quadruplex; Lead (II) ion; Practical application