title: Do Cardiovascular Risk Factors and Coronary SYNTAX Score Predict Contrast Volume Use During Cardiac Catheterization?
abstract: The association of cardiovascular risk factors and complexity and severity of coronary artery disease with contrast volume (CV) remains unknown. We assessed the predictive factors of CV use during elective and emergent cardiac catheterization (CC). Electronic medical records from 2010 to 2013 were retrospectively reviewed. A total of 708 patients were eligible. On multivariable regression analysis, the presence of obstructed coronary arteries was associated with CV (P = .01, β = -14.17), with greater CV used in patients with single or double vessel disease compared to those with triple vessel disease. The presence of lesions with >70% stenosis in major epicardial arteries (P = .019, β = 24.39) and ST-segment elevation myocardial infarction (P = .001, β = 36.14) was associated with increased CV use. Elevated B-type natriuretic peptide (P = .036, β = -17.23) and increase in Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery score (P = .024, β = -29.06) were associated with decreased CV use. These aforementioned associations were attenuated after adjusting for percutaneous coronary intervention. Our findings may help predict patient populations who could be exposed to increased CV during CC, thereby possibly increasing their risk of contrast-induced nephropathy.
authors.affiliation: Department of Internal Medicine, Lutheran Medical Center, Brooklyn, NY, USA cardiothorax@gmail.com.
authors.forename: Hemal
authors.initials: H
authors.lastname: Bhatt
authors.affiliation: Department of Internal Medicine, Lutheran Medical Center, Brooklyn, NY, USA.
authors.forename: Atika
authors.initials: A
authors.lastname: Turkistani
authors.affiliation: Department of Internal Medicine, Lutheran Medical Center, Brooklyn, NY, USA.
authors.forename: Dharmesh
authors.initials: D
authors.lastname: Sanghani
authors.affiliation: Department of Internal Medicine, Lutheran Medical Center, Brooklyn, NY, USA.
authors.forename: Kell
authors.initials: K
authors.lastname: Julliard
authors.affiliation: Department of Cardiology, Lutheran Medical Center, Brooklyn, NY, USA.
authors.forename: George
authors.initials: G
authors.lastname: Fernaine
mesh_terms: D000368:Aged; D006328:Cardiac Catheterization / Q000009:adverse effects*; D016009:Chi-Square Distribution; D015897:Comorbidity; D003287:Contrast Media / Q000009:adverse effects*; D017023:Coronary Angiography / Q000009:adverse effects*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000628:therapy*; D003430:Cross-Sectional Studies; D057286:Electronic Health Records; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects*; D011237:Predictive Value of Tests; D015641:Radiography, Interventional / Q000009:adverse effects; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D003287:Contrast Media
keywords: SYNTAX score; cardiovascular risk factors; contrast volume; coronary artery disease; coronary lesions