title: Chromium content in the human hip joint tissues.
abstract: OBJECTIVE
  Chromium has many important functions in the human body. For the osseous tissue, its role has not been clearly defined. This study was aimed at determining chromium content in hip joint tissues.
  
  
  METHODS
  A total of 91 hip joint samples were taken in this study, including 66 from females and 25 from males. The sample tissues were separated according to their anatomical parts. The chromium content was determined by the AAS method. The statistical analysis was performed with U Mann-Whitney's non-parametric test, P≤0.05.
  
  
  RESULTS
  The overall chromium content in tissues of the hip joint in the study subjects was as follows: 5.73 µg/g in the articular cartilage, 5.33 µg/g in the cortical bone, 17.86 µg/g in the cancellous bone, 5.95 µg/g in the fragment of the cancellous bone from the intertrochanteric region, and 1.28 µg/g in the joint capsule. The chromium contents were observed in 2 group patients, it was 7.04 µg/g in people with osteoarthritis and 12.59 µg/g in people with fractures.
  
  
  CONCLUSIONS
  The observed chromium content was highest in the cancellous bone and the lowest in the joint capsule. Chromium content was significantly different between the people with hip joint osteoarthritis and the people with femoral neck fractures.
authors.affiliation: School of Pharmacy with the Division of Laboratory Medicine, Department of Toxicology, Medical University of Silesia, 4 Jagiellonska, Str. 41-200 Sosnowiec, Poland.
authors.forename: Barbara
authors.initials: B
authors.lastname: Brodziak-Dopierała
authors.affiliation: Institute of Occupational Medicine and Environmental Health, 13 Kościelna, Str. 41-200 Sosnowiec, Poland.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Kwapuliński
authors.affiliation: Municipal Hospital, Department of Traumatic Surgery, May-1 Str. 41-100 Siemianowice Slaskie, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Sobczyk
authors.affiliation: School of Pharmacy with the Division of Laboratory Medicine, Department of Toxicology, Medical University of Silesia, 4 Jagiellonska, Str. 41-200 Sosnowiec, Poland.
authors.forename: Danuta
authors.initials: D
authors.lastname: Wiechuła
mesh_terms: D000368:Aged; D001842:Bone and Bones / Q000737:chemistry*; D002358:Cartilage, Articular / Q000737:chemistry*; D002857:Chromium / Q000737:chemistry*; D004781:Environmental Exposure; D004785:Environmental Pollutants / Q000737:chemistry* / Q000378:metabolism; D005260:Female; D006621:Hip Joint / Q000737:chemistry*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012907:Smoking
chemical_list: D004785:Environmental Pollutants; D002857:Chromium
keywords: Cancellous bone; Chromium; Cortical bone; Femur head; Hip joint