title: Diagnostic value of endorectal ultrasonography for rectal carcinoma: a meta-analysis.
abstract: OBJECTIVE
  The aim of this meta-analysis was to evaluate the diagnosis efficacy of endorectal ultrasonography (ERUS) for rectal carcinoma.
  
  
  METHODS
  We searched all the published articles about ERUS in evaluation of rectal carcinoma in the electronic databases. The pooled diagnosis sensitivity, specificity, diagnosis odds ratio, a positive likelihood ratio, negative likelihood ratio, and area under the receiver operating characteristic (ROC) were calculated by MetaDiSc-1.4 software.
  
  
  RESULTS
  Fourteen studies with 1583 subjects meeting the inclusion criteria were recruited in this meta-analysis. For tumor invasion evaluated by ERUS, the pooled diagnosis sensitivity, specificity, diagnosis odds ratio, positive likelihood ratio, negative likelihood ratio and area under the ROC were 0.95 (0.92-0.97), 0.80 (0.71-0.86), 62.88 (9.30-425.33), 3.66 (2.48-5.39), 0.07 (0.01-0.40), and 0.86; for lymph node involvement evaluated by EU, the pooled diagnosis sensitivity, specificity, diagnosis odds ratio, positive likelihood ratio, negative likelihood ratio and area under the ROC were 0.58 (0.53-0.63), 0.80 (0.77-0.84), 5.93 (4.07-8.63), 2.85 (2.30-3.52), 0.54 (0.46-0.63) and 0.78.
  
  
  CONCLUSIONS
  ERUS was a good method for the assessment of invasion of rectal tumors and lymph node involvement.
authors.affiliation: Department of Clinical Laboratory, The 2nd People's Hospital of Tianjin, Tianjin 300192, China.
authors.forename: Yonghe
authors.initials: Y
authors.lastname: Zhou
authors.forename: Wei
authors.initials: W
authors.lastname: Shao
authors.affiliation: Department of Clinical Laboratory, The 2nd People's Hospital of Tianjin, Tianjin 300192, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Lu
mesh_terms: D019540:Area Under Curve; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D012372:ROC Curve; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging*; D014463:Ultrasonography