title: Solid-Phase Extraction Followed by Dispersive Liquid-Liquid Microextraction Based on Solidification of Floating Organic Drop for the Determination of Parabens.
abstract: A dispersive liquid-liquid microextraction based on solidification of floating organic drop method combined with solid-phase extraction (500-mg C18 sorbent) was developed for preconcentration and determination of some parabens. The experimental parameters influencing the extraction efficiency such as the type of extraction and disperser solvents, as well as their volumes, breakthrough volume, flow rate and salt addition were studied and optimized. The optimum experimental conditions found included: sample volume, 100 mL; KCl concentration, 1% (w/v); extraction solvent (1-undecanol) volume, 20 µL and disperser solvent (acetone) volume, 250 µL. Under the optimum experimental conditions, calibration graphs were linear in the range of 1-200 µg L(-1) with limits of detection ranged from 0.3 to 1.7 µg L(-1). The relative standard deviations were in the range of 1.2-3.1% (n = 5). The enrichment factors and absolute recoveries of parabens in different matrices were 245-1886 and 9.0-69.8%, respectively. The method was applied to the simultaneous determination of parabens in different matrices. The relative recoveries from water, shampoo and mouth rinse samples, which have been spiked at different levels of parabens, were 87.83-112.25%, 82.80-108.40% and 90.10-97.60%, respectively.
authors.affiliation: Department Chemistry, Razi University, Kermanshah, Iran.
authors.forename: Beshare
authors.initials: B
authors.lastname: Hashemi
authors.affiliation: Department Chemistry, Razi University, Kermanshah, Iran.
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Shamsipur
authors.affiliation: Research Center for Environmental Determinants of Health (RCEDH), Kermanshah University of Medical Sciences, Kermanshah, Iran nazirfatahi@yahoo.com.
authors.forename: Nazir
authors.initials: N
authors.lastname: Fattahi
mesh_terms: D002851:Chromatography, High Pressure Liquid; D060766:Drinking Water / Q000737:chemistry; D006795:Household Products / Q000032:analysis; D057230:Limit of Detection; D016014:Linear Models; D059627:Liquid Phase Microextraction / Q000379:methods*; D010226:Parabens / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification*; D015203:Reproducibility of Results; D052616:Solid Phase Extraction / Q000379:methods*
chemical_list: D060766:Drinking Water; D010226:Parabens