title: Crystal structure of (2S,4R)-ethyl 4-nitro-methyl-1-[(S)-1-phenyl-eth-yl]-6-sulfanyl-idene-piperidine-2-carboxyl-ate.
abstract: In the title compound, C17H22N2O4S, a thio-piperidine derivative, the piperidine ring has an envelope conformation with the methyl-ene C atom opposite to the C=S bond as the flap. The nitro-methyl substituent is equatorial while the eth-oxy-carbonyl group is axial. The mean planes of the nitro-methyl group, the carb-oxy group and phenyl ring are inclined to the mean plane through the five planar atoms of the piperidine ring [maximum deviation = 0.070 (4) Å] by 56.8 (2), 83.8 (5) and 87.1 (2)°, respectively. There is an intra-molecular C-H⋯O hydrogen bond involving an H atom of the eth-oxy-carbonyl group and a nitro O atom. In the crystal, mol-ecules are linked by C-H⋯O hydrogen bonds, forming chains along [100]. The chains are linked by further C-H⋯O hydrogen bonds, forming corrugated layers lying parallel to (001).
authors.affiliation: Centro de Química, ICUAP, Benemérita Universidad Autónoma de Puebla, 72570, Puebla, Puebla, Mexico.
authors.forename: Araceli
authors.initials: A
authors.lastname: Zárate
authors.affiliation: Centro de Química, ICUAP, Benemérita Universidad Autónoma de Puebla, 72570, Puebla, Puebla, Mexico.
authors.forename: David
authors.initials: D
authors.lastname: Aparicio
authors.affiliation: Centro de Química, ICUAP, Benemérita Universidad Autónoma de Puebla, 72570, Puebla, Puebla, Mexico.
authors.forename: Angel
authors.initials: A
authors.lastname: Palillero
authors.affiliation: Centro de Química, ICUAP, Benemérita Universidad Autónoma de Puebla, 72570, Puebla, Puebla, Mexico.
authors.forename: Angel
authors.initials: A
authors.lastname: Mendoza
keywords: crystal structure; hydrogen bonding; piperidine-2-thio­nes; thio­piperidine