title: [Acute coronary syndrome following a 100 µg carbetocin injection during an emergency Cesarean delivery].
abstract: OBJECTIVE
  Postpartum hemorrhage affects 5% of parturients. Its prevention relies mainly on the administration of oxytocin derivatives. Carbetocin is a newly available analogue of oxytocin but has a considerable incidence of side effects.
  
  
  METHODS
  We report the case of a woman with no cardiovascular risk factors experiencing an acute coronary syndrome with significant electrocardiogram changes perioperatively after a single injection of carbetocin during an emergency Cesarean delivery. Postoperative cardiac enzyme levels and transthoracic echocardiogram results were normal.
  
  
  CONCLUSIONS
  A 2012 retrospective analysis of the use of carbetocin in our institution revealed an incidence rate for coronary events of 1/245 (0.34%), a rate similar to the ones reported in previous studies. We discuss the management of patients with angina during a Cesarean delivery as well as the plans to care for these patients in the future.
authors.affiliation: Service d'anesthésie, Centre hospitalier Fleyriat, Bourg en Bresse, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Jacquenod
authors.forename: Mathilde
authors.initials: M
authors.lastname: Cattenoz
authors.forename: Guillaume
authors.initials: G
authors.lastname: Canu
authors.forename: Elodie
authors.initials: E
authors.lastname: Bois
authors.forename: Thomas
authors.initials: T
authors.lastname: Lieutaud
mesh_terms: D054058:Acute Coronary Syndrome / Q000139:chemically induced*; D000328:Adult; D002585:Cesarean Section / Q000379:methods*; D004452:Echocardiography; D005260:Female; D006801:Humans; D010120:Oxytocics / Q000008:administration & dosage / Q000009:adverse effects*; D010121:Oxytocin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D011247:Pregnancy
chemical_list: D010120:Oxytocics; D010121:Oxytocin; C020731:carbetocin