title: Progress and developments in the turbo Grignard reagent i-PrMgCl·LiCl: a ten-year journey.
abstract: Over the past decade, the effectiveness of i-PrMgCl·LiCl has been constantly highlighted by a number of research groups. Its enhanced nucleophilicity brings prosperity to highly functionalized Grignard reagents, other useful bimetallic (alkali-metal) agents and nucleophilic alkylation products under mild reaction conditions. In this feature article, a comprehensive, systematical and in-depth overview of i-PrMgCl·LiCl is provided in a multidisciplinary idea. It involves the structural and kinetic perspectives of i-PrMgCl·LiCl as well as its unique reactivity and selectivity, with knowledge of the former helping to rationalize trends of the later.
authors.affiliation: Institute of Organic Chemistry, The Academy of Fundamental and Interdisciplinary Science, Harbin Institute of Technology, Harbin 150080, P. R. China. lshi@hit.edu.cn.
authors.forename: Robert Li-Yuan
authors.initials: RL
authors.lastname: Bao
authors.forename: Rong
authors.initials: R
authors.lastname: Zhao
authors.forename: Lei
authors.initials: L
authors.lastname: Shi