title: Molecular adaptations in human atrial fibrillation: mechanisms of protein remodelling.
abstract: The chance that the treatment of atrial fibrillation (AF) is successful depends on the duration of the arrhythmia. The low efficacy of cardioversion therapy after long-term AF can be explained by the occurrence of cellular adaptation mechanisms. In this article we describe ion-channel protein remodelling and structural changes in the atria of patients with persistent and paroxysmal AF and its relation with electrical remodelling.
authors.forename: B J J M
authors.initials: BJ
authors.lastname: Brundel
authors.forename: R H
authors.initials: RH
authors.lastname: Henning
authors.forename: W H
authors.initials: WH
authors.lastname: van Gilst
authors.forename: I C
authors.initials: IC
authors.lastname: van Gelder
authors.forename: H J G M
authors.initials: HJ
authors.lastname: Crijns
keywords: atrial fibrillation; calpain; human; ion channels; remodelling