title: A step forward in elucidating the mystery of OCD.
abstract: Obsessive-compulsive disorder represents one of the most disabling psychiatric disorders. The underlying pathophysiology is not fully understood. In a recent Science article, Ahmari and colleagues enlighten fundamental aspects of obsessive-compulsive disorder by means of optogenetic stimulation, thereby also elucidating the usefulness of SSRI in the treatment for OCD.
authors.affiliation: Department of Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany.
authors.forename: Sina
authors.initials: S
authors.lastname: Kohl
authors.affiliation: Department of Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany.
authors.forename: Lena
authors.initials: L
authors.lastname: Ebbert
authors.affiliation: Department of Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health (CIMH), University of Heidelberg, Mannheim, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Sartorius
authors.affiliation: Department of Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany. jens.kuhn@uk-koeln.de.
authors.forename: Jens
authors.initials: J
authors.lastname: Kuhn
mesh_terms: D000818:Animals; D003342:Corpus Striatum / Q000503:physiopathology*; D005625:Frontal Lobe / Q000503:physiopathology*; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000503:physiopathology* / Q000523:psychology*; D013788:Thalamus / Q000503:physiopathology*
keywords: Deep brain stimulation; Obsessive compulsive disorder; Optogenetic stimulation