title: Prevalence of foot eczema and associated occupational and non-occupational factors in patients with hand eczema.
abstract: BACKGROUND
  Foot eczema often occurs in combination with hand eczema. However, in contrast to the situation with hand eczema, knowledge about foot eczema is scarce, especially in occupational settings.
  
  
  OBJECTIVE
  To evaluate the prevalence of foot eczema and associated factors in patients with hand eczema taking part in a tertiary individual prevention programme for occupational skin diseases.
  
  
  METHODS
  In a retrospective cohort study, the medical records of 843 patients taking part in the tertiary individual prevention programme were evaluated.
  
  
  RESULTS
  Seven hundred and twenty-three patients (85.8%) suffered from hand eczema. Among these, 201 patients (27.8%) had concomitant foot eczema, mainly atopic foot eczema (60.4%). An occupational irritant component was possible in 38 patients with foot eczema (18.9%). In the majority of patients, the same morphological features were found on the hands and feet (71.1%). The presence of foot eczema was significantly associated with male sex [odds ratio (OR) 1.78, 95% confidence interval (CI) 1.29-2.49], atopic hand eczema (OR 1.60, 95%CI: 1.15-2.22), hyperhidrosis (OR 1.73, 95%CI: 1.33-2.43), and the wearing of safety shoes/boots at work (OR 2.04, 95%CI: 1.46-2.87). Tobacco smoking was associated with foot eczema (OR 1.79, 95%CI: 1.25-2.57), in particular with the vesicular subtype.
  
  
  CONCLUSIONS
  Foot eczema is common in patients with hand eczema, and is related to both occupational and non-occupational factors.
authors.affiliation: Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, D-49090, Osnabrück, Germany.|Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm), University of Osnabrück, D-49090, Osnabrück, Germany.|Lower-Saxonian Institute of Occupational Dermatology, University of Osnabrück, D-49090, Osnabrück, Germany.
authors.forename: Richard
authors.initials: R
authors.lastname: Brans
authors.affiliation: Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, D-49090, Osnabrück, Germany.
authors.forename: Anja
authors.initials: A
authors.lastname: Hübner
authors.affiliation: FB 7 Psychology: Methodology & Statistics, University of Münster, D-48149, Münster, Germany.
authors.forename: Günther
authors.initials: G
authors.lastname: Gediga
authors.affiliation: Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabrück, D-49090, Osnabrück, Germany.|Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm), University of Osnabrück, D-49090, Osnabrück, Germany.|Lower-Saxonian Institute of Occupational Dermatology, University of Osnabrück, D-49090, Osnabrück, Germany.
authors.forename: Swen M
authors.initials: SM
authors.lastname: John
mesh_terms: D000328:Adult; D015331:Cohort Studies; D017449:Dermatitis, Allergic Contact / Q000453:epidemiology*; D003877:Dermatitis, Contact / Q000453:epidemiology; D017453:Dermatitis, Irritant / Q000453:epidemiology*; D009783:Dermatitis, Occupational / Q000453:epidemiology*; D004485:Eczema / Q000453:epidemiology; D004781:Environmental Exposure / Q000706:statistics & numerical data; D005260:Female; D005511:Food Handling; D005533:Foot Dermatoses / Q000453:epidemiology*; D005858:Germany / Q000453:epidemiology; D006229:Hand Dermatoses / Q000453:epidemiology*; D019981:Health Care Sector; D006796:Household Work; D006801:Humans; D008297:Male; D008670:Metals; D008875:Middle Aged; D016273:Occupational Exposure / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012907:Smoking / Q000453:epidemiology
chemical_list: D008670:Metals
keywords: foot eczema; irritant contact dermatitis; occupational; tobacco smoking