title: [Lung involvement in patients with primary biliary cirrhosis].
abstract: METHODS
  For several months a 29 years old woman suffered from dry cough, dyspnea, and weakness. The clinical examination was without any abnormal findings.
  
  
  METHODS
  Liver function tests and erythrocyte sedimentation rate were raised. High resolution CT chest scan showed multiple patchy alveolar and interstitial infiltrates. Transbronchial and surgical lung biopsy confirmed a moderate alveolitis with granulomas.
  
  
  METHODS
  primary biliary cirrhosis (pbc) complicated by lung disease could be diagnosed through increased titer of antimitochondrial antibodies and the laparoscopy.
  
  
  METHODS
  Under treatment of pbc with either corticosteroids or Ursodeoxycholic acid, liver enzymes decreased and pulmonary symptoms disappeared.
  
  
  CONCLUSIONS
  To detect lung involvement in patients with pbc early, lung function tests and diffusion capacity should be monitored regularly. An otherwise unexpected rise in liver function tests, particularly in patients with underlying interstitial lung disease or sarcoid granulomatosis should promptly be investigated further.
authors.affiliation: Abteilung Pneumolgie, pneumologische Onkologie, Rehabilitation sowie Schlaf- und Beatmungsmedizin, Thoraxzentrum des Bezirks Unterfranken, Münnerstadt.
authors.forename: Karen
authors.initials: K
authors.lastname: Laudenbach
authors.affiliation: Abteilung Pneumolgie, pneumologische Onkologie, Rehabilitation sowie Schlaf- und Beatmungsmedizin, Thoraxzentrum des Bezirks Unterfranken, Münnerstadt.
authors.forename: Bernd
authors.initials: B
authors.lastname: Seese
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001323:Autoantibodies / Q000097:blood; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D008168:Lung / Q000276:immunology; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D008928:Mitochondria; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D001323:Autoantibodies; D014580:Ursodeoxycholic Acid