title: [Biological effect of extracellular peptide factor from Lateococcus japonicas subsp. casei on probiotic bacteria].
abstract: The biological effect of the extracellular peptide reactivating factor (RF) from Luteococcus casei on cells of probiotic cultures was studied. The RF showed the protective and reactivating effects on the Bifidobacterium bifidum cells under the action of bile salts and an acidic stress. Also, it acted as a cryoprotector during lyophilisation and long-term culture storage. The RF and the L. casei culture liquid (CL) were shown to have bifidogenic properties. The degree of protection and reactivation of lactic-acid bacteria under the action of bile salts depended on the particular strain properties. The maximum degree of protection (more than thirteen-fold) and reactivation (close to three-fold) was found in Lactobacillus casei, while the minimum values were characteristic of Lactobacillus reuterii. The resistance of lactobacilli to bile was increased in the row of L. acidophilus, L. casei, L. plantarum, L. rhamnosus, and L. reuterii correlating with the RF protection degree.
authors.forename: L I
authors.initials: LI
authors.lastname: Vorob'eva
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Khodzhaev
authors.forename: N V
authors.initials: NV
authors.lastname: Kharchenko
authors.forename: T M
authors.initials: TM
authors.lastname: Novikova
authors.forename: T A
authors.initials: TA
authors.lastname: Cherdyntseva
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism / Q000494:pharmacology*; D001644:Bifidobacterium / Q000187:drug effects* / Q000254:growth & development; D001647:Bile Acids and Salts / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D003451:Cryoprotective Agents / Q000378:metabolism / Q000494:pharmacology*; D005612:Freeze Drying; D007779:Lactobacillus acidophilus / Q000378:metabolism; D007780:Lacticaseibacillus casei / Q000378:metabolism*; D048191:Lactiplantibacillus plantarum / Q000378:metabolism; D052200:Limosilactobacillus reuteri / Q000378:metabolism; D052201:Lacticaseibacillus rhamnosus / Q000378:metabolism; D019936:Probiotics; D013045:Species Specificity; D013312:Stress, Physiological
chemical_list: D001426:Bacterial Proteins; D001647:Bile Acids and Salts; D003451:Cryoprotective Agents