title: The influence of fetal growth restriction on cardiovascular health among adolescents in Brazil: a retrospective cohort study.
abstract: OBJECTIVE
  To investigate whether fetal growth restriction is associated with changes in cardiovascular risk factors later in life.
  
  
  METHODS
  A retrospective cohort study.
  
  
  METHODS
  Tertiary-care hospital serving urban population from the Brazilian Northeast.
  
  
  METHODS
  172 adolescents aged 10-20 years were evaluated for the effects of fetal growth restriction on anthropometric measurements, blood pressure, lipids and fasting glucose and flow-mediated brachial artery dilatation.
  
  
  METHODS
  The adolescents' birth weight and their gestational age at birth were used to identify fetal growth restriction according to the 10th percentile and divided between exposed (<10th percentile) and not exposed (≥10th percentile). The Student-t test or the Mann-Whitney test and chi-square were used. The significance level was considered to be 0.05.
  
  
  METHODS
  Current Anthropometric, metabolic and endothelial measures of subjects.
  
  
  RESULTS
  The majority of the current anthropometric, metabolic and endothelial measures did not differ between groups. The unexposed group had a higher hip circumference (89.1 cm) and higher total cholesterol (196.4mg/dL) than those exposed (85.4 cm, 136.9mg/dL, respectively) (P=0.04).
  
  
  CONCLUSIONS
  In the sample studied, no association was found between fetal growth restriction and changes in cardiovascular risk factors in adolescents.
authors.affiliation: Department of Community Health, *Faculty of Medicine, and #Department of Maternal and Child Health, Federal University of Ceara, Fortaleza, Brazil. Correspondence to: Priscilla de Jesus dos Santos Alves. Department of Community Health, Faculty of Medicine, Federal University of Ceara. R. Prof. Costa Mendes 1608/5º andar, Rodolfo Teófilo. CEP: 60430-140, Fortaleza-CE. prisciladjs@gmail.com.
authors.forename: P J S
authors.initials: PJ
authors.lastname: Alves
authors.forename: A C P T
authors.initials: AC
authors.lastname: Henriques
authors.forename: K F
authors.initials: KF
authors.lastname: Silva
authors.forename: A J M
authors.initials: AJ
authors.lastname: Leite
authors.forename: F E L
authors.initials: FE
authors.lastname: Feitosa
authors.forename: C H M
authors.initials: CH
authors.lastname: Alencar
authors.forename: F H C
authors.initials: FH
authors.lastname: Carvalho
mesh_terms: D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D001938:Brazil / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D002648:Child; D002784:Cholesterol / Q000097:blood; D005260:Female; D005317:Fetal Growth Retardation / Q000453:epidemiology*; D005865:Gestational Age; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult
chemical_list: D002784:Cholesterol