title: Cutaneous and gastrointestinal symptoms in two patients with systemic mastocytosis successfully treated with omalizumab.
abstract: The pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti-IgE) reduced gastrointestinal and cutaneous symptoms significantly. This observation provides additional insight into the effects of omalizumab on systemic mastocytosis.
authors.affiliation: Department of Dermatology, Bispebjerg Hospital, 2400 Copenhagen NV, Denmark.
authors.forename: Sofie
authors.initials: S
authors.lastname: Lieberoth
authors.affiliation: Department of Dermatology, Bispebjerg Hospital, 2400 Copenhagen NV, Denmark.
authors.forename: Simon Francis
authors.initials: SF
authors.lastname: Thomsen