title: [Effect of cell therapy in patients with chronic ischaemic heart disease--a survey of a Cochrane review].
abstract: The present Cochrane review included 23 studies randomized placebo-controlled clinical trials with a total of 1,255 patients. The effect of autologous cell therapy versus placebo was examined on left ventricular ejection fraction (LVEF), adverse effects and mortality in patients with chronic ischaemic heart disease. Patients treated with cell therapy had improved LVEF and functional status compared to patients who received placebo. There were no cell-related and only few procedure-related side effects. A positive effect of cell therapy on long-term survival was also demonstrated.
authors.affiliation: Kardiologisk Laboratorium 2014, Hjertecenteret, Rigshospitalet, Blegdamsvej 9, 2100 København Ø. abbe@dadlnet.dk.
authors.forename: Anders Bruun
authors.initials: AB
authors.lastname: Mathiasen
authors.forename: Abbas Ali
authors.initials: AA
authors.lastname: Qayyum
authors.forename: Jens
authors.initials: J
authors.lastname: Kastrup
mesh_terms: D002908:Chronic Disease; D006801:Humans; D017202:Myocardial Ischemia / Q000628:therapy*; D012196:Review Literature as Topic; D033581:Stem Cell Transplantation; D014182:Transplantation, Autologous; D016896:Treatment Outcome