title: Association of diet with prostate specific antigen and prostate volume.
abstract: BACKGROUND
  Prostate is an important male reproductive system gland and its disorders can affect men's quality of life and health. Prostatitis, benign prostatic hyperplasia (BPH), and prostate adenocarcinoma are major disorders that can be found in all men in different ages.
  
  
  OBJECTIVE
  The aim of this study was to investigate the association of diet with serum prostate specific antigen (PSA) level as well as prostate volume.
  
  
  METHODS
  In this cross-sectional study, 950 men older than 40 years of age who had attended our clinic for a screening program for prostate cancer were enrolled. Data was extracted from the program database. The eligible cases included all noncancerous subjects with available data concerning serum PSA level and prostate volume; the patients had completed a 50-item self-administered food frequency questionnaire about their diet during the preceding two year.
  
  
  RESULTS
  No overall association was found between the consumption of foods and prostate volume as well as serum PSA level. There was a significant correlations between age and serum PSA level (r = 0.24) as well as with prostate volume (r = 0.22) (P < 0.001). In addition, there was a significant correlation between serum PSA level and prostate volume (r = 0.41 and P < 0.001).
  
  
  CONCLUSIONS
  The results of this study confirmed the previous reports regarding the serum PSA level correlation with prostate volume. There was no evidence that dietary patterns might have any important effect on prostate volume and serum PSA in this Iranian population.
authors.affiliation: Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, IR Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Shirazi
authors.affiliation: Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, IR Iran ; Urology Oncology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Ariafar
authors.affiliation: Urology Oncology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
authors.forename: Shahryar
authors.initials: S
authors.lastname: Zeyghami
authors.affiliation: Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, IR Iran.
authors.forename: Mohammad Mehdi
authors.initials: MM
authors.lastname: Hosseini
authors.affiliation: Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, IR Iran.
authors.forename: Abdol Aziz
authors.initials: AA
authors.lastname: Khezri
keywords: Diet; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia