title: The effect of home-use and in-office bleaching treatments combined with experimental desensitizing agents on enamel and dentin.
abstract: OBJECTIVE
  This study aimed to evaluate in vitro the effect of formulations containing Biosilicate to treat enamel and dentin bovine samples exposed to dental bleaching agents.
  
  
  METHODS
  On enamel and dentin bleached with commercial gels containing 16% carbamide peroxide (CP) (14 days/4 h) or 35% hydrogen peroxide (single session/45 min), desensitizing dentifrices (Sensodyne(®); experimental dentifrice of Biosilicate(®); Odontis RX(®); Sorriso(®)) were applied along 14 days and desensitizing pastes (Biosilicate(®)/water 1:1; Dessensebilize NanoP(®); Bioglass type 45S5/water 1:1) were applied on days 1, 3, 7, 10 and 14. Distilled water was the control. Microhardness (MH) and roughness measurements were the variables measured on the samples before and after the treatments. Student's t-test analyzed differences before and after the treatments. Two-way analysis of variance and post-hoc Tukey test analyzed differences among the factors desensitizing, bleaching agents and substrate.
  
  
  RESULTS
  Tukey test showed no differences in roughness for both bleaching treatments and among the desensitizing agents (P > 0.05). Differences in MH appeared on enamel treated with in-home bleaching when control group (lower values) was compared with Sensodyne, Biosilicate dentifrice, Biosilicate paste, and Bioglass paste (higher values). Comparisons between desensitizing agents on dentin treated with both bleaching gels showed no statistical differences.
  
  
  CONCLUSIONS
  The effect of formulations containing Biosilicate (Biosilicate dentifrice and paste) was significant in the MH of enamel bleached with 16% CP.
authors.affiliation: Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
authors.forename: Karen
authors.initials: K
authors.lastname: Pintado-Palomino
authors.affiliation: Department of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
authors.forename: Camila
authors.initials: C
authors.lastname: Tirapelli
keywords: Biomaterial; carbamide peroxide; dental bleaching; hydrogen peroxide