title: Review of safety considerations in the elderly using sulfonylureas.
abstract: Sulfonylureas (SUs) are a class of medications used to treat type 2 diabetes mellitus that work by increasing insulin secretion in the pancreas. Second-generation SUs are most often used today because of adverse effects with those in the first generation. However, there is still a risk of hypoglycemia even with the newer medications in the class. The American Diabetes Association encourages a patient-centered approach when initiating pharmacologic therapy. Understanding the pharmacokinetic differences among these medications can allow the consultant pharmacist to make a decision on which medication may be best suited for the patient.
authors.affiliation: St. John's University College of Pharmacy and Health Sciences 8000 Utopia Parkway, Queens, NY 11439, USA.
authors.forename: Samad
authors.initials: S
authors.lastname: Tirmizi
authors.forename: Nissa
authors.initials: N
authors.lastname: Mazzola
mesh_terms: D000368:Aged; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects*; D010595:Pharmacists; D024382:Professional Role; D013453:Sulfonylurea Compounds / Q000009:adverse effects*
chemical_list: D007004:Hypoglycemic Agents; D013453:Sulfonylurea Compounds