title: Copper catalysed amidation of aryl halides through chelation assistance.
abstract: A copper mediated C-N bond formation for the amidation of aryl halides using 8-aminoquinoline has been developed. This strategy provides efficient access to amides bearing two contiguous heterocyclic moieties and does not require the presence of additional ligands.
authors.affiliation: Bioorganic & Biophysical Chemistry Laboratory, Linnaeus University Centre for Biomaterials Chemistry, Linnæus University, SE-391 82 Kalmar, Sweden. ian.nicholls@lnu.se.
authors.forename: Subban
authors.initials: S
authors.lastname: Kathiravan
authors.forename: Shishir
authors.initials: S
authors.lastname: Ghosh
authors.forename: Graeme
authors.initials: G
authors.lastname: Hogarth
authors.forename: Ian A
authors.initials: IA
authors.lastname: Nicholls
mesh_terms: D000577:Amides / Q000737:chemistry*; D000634:Aminoquinolines / Q000737:chemistry*; D002384:Catalysis; D002614:Chelating Agents / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000577:Amides; D000634:Aminoquinolines; D002614:Chelating Agents; D003300:Copper; C080436:8-aminoquinoline