title: Science to Practice: can MR relaxation and diffusion measurements be used to detect in vivo differentiation of transplanted muscle precursor cells?
abstract: Tissue magnetic resonance (MR) relaxometry and diffusion measurements were successfully used to detect the differentiation of implanted human muscle precursor cells (MPCs) into mature skeletal muscle. As no contrast agents are required, this label-free imaging approach may be immediately used in patients to evaluate the outcome of stem cell- and progenitor cell-based therapies aimed to restore defunct muscle.
authors.affiliation: Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, Cellular Imaging Section, Institute for Cell Engineering, The Johns Hopkins University School of Medicine 720 Rutland Ave, 217 Traylor Baltimore, MD 21205.
authors.forename: Jeff W M
authors.initials: JW
authors.lastname: Bulte
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D008279:Magnetic Resonance Imaging; D018482:Muscle, Skeletal / Q000166:cytology*; D032446:Myoblasts / Q000166:cytology*