title: Evaluating mean platelet volume as a new indicator for confirming the diagnosis of necrotizing pancreatitis.
abstract: BACKGROUND
  The aim of the present study is to discuss the possible role of mean platelet volume as a new predictor in the diagnosis of necrotizing pancreatitis.
  
  
  METHODS
  Study subjects are arranged in three different groups: Group I; control group (n= 40), Group II; acute pancreatitis (n= 40), Group III; necrotizing pancreatitis (n= 36). Demographic data and mean platelet volume values are recorded retrospectively.
  
  
  RESULTS
  Mean platelet volume of patients in Group II was 7.9±0.53, while in Group III patients it was 7.2±0.52 (p<0.001). When we compared the study groups with ROC analysis, results demonstrated that cut off value of necrotizing pancreatitis patients as 7,8 (area under curve: 0.857), sensitivity as 86.1% and specificity as 72.5%.
  
  
  CONCLUSIONS
  The current study shows that mean platelet volume in necrotizing pancreatitis patients is significantly reduced compared to that of patients in the control and acute pancreatitis group.
authors.forename: Halil
authors.initials: H
authors.lastname: Erbis
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Aliosmanoglu
authors.forename: Mehmet Akif
authors.initials: MA
authors.lastname: Turkoglu
authors.forename: Enver
authors.initials: E
authors.lastname: Ay
authors.forename: Ahmet
authors.initials: A
authors.lastname: Turkoglu
authors.forename: Burak Veli
authors.initials: BV
authors.lastname: Ulger
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis; D019283:Pancreatitis, Acute Necrotizing / Q000097:blood* / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011379:Prognosis; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers