title: Left atrial appendage closure for thromboembolism prevention in patients with atrial fibrillation: advances and perspectives.
abstract: Atrial fibrillation (AF) is a frequent cause of stroke. More than 90% of thrombi were found in the left atrial appendage (LAA) in non-valvular AF. Transcatheter LAA closure has been developed as a novel approach to reduce the risk of stroke in patients with AF over the last decade. In this article, we review the recent advances and propose the possible challenges regarding the LAA closure for thromboembolism prevention in patients with AF.
authors.affiliation: 1 Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China ; 2 Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Kong
authors.affiliation: 1 Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China ; 2 Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.affiliation: 1 Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China ; 2 Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China.
authors.forename: He
authors.initials: H
authors.lastname: Huang
authors.affiliation: 1 Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China ; 2 Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Jiang
authors.affiliation: 1 Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China ; 2 Cardiovascular Research Institute, Wuhan University, Wuhan 430060, China.
authors.forename: Congxin
authors.initials: C
authors.lastname: Huang
keywords: Atrial fibrillation (AF); left atrial appendage (LAA) closure; stroke