title: YAP and the drug resistance highway.
abstract: Deciphering mechanisms of drug resistance is crucial to winning the battle against cancer. A new study points to an unexpected function of YAP in drug resistance and illuminates its potential role as a therapeutic target.
authors.affiliation: Weizmann Institute of Science, Rehovot, Israel.
authors.forename: Alona
authors.initials: A
authors.lastname: Keren-Paz
authors.affiliation: Weizmann Institute of Science, Rehovot, Israel.
authors.forename: Rafi
authors.initials: R
authors.lastname: Emmanuel
authors.affiliation: Weizmann Institute of Science, Rehovot, Israel.
authors.forename: Yardena
authors.initials: Y
authors.lastname: Samuels
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics*; D000818:Animals; D005260:Female; D000090683:Hippo Signaling Pathway; D006801:Humans; D020930:MAP Kinase Kinase Kinases / Q000037:antagonists & inhibitors*; D010750:Phosphoproteins / Q000235:genetics*; D047428:Protein Kinase Inhibitors / Q000494:pharmacology*; D017346:Protein Serine-Threonine Kinases / Q000235:genetics*; D048493:Proto-Oncogene Proteins B-raf / Q000037:antagonists & inhibitors*; D014157:Transcription Factors; D000091102:YAP-Signaling Proteins
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D010750:Phosphoproteins; D047428:Protein Kinase Inhibitors; D014157:Transcription Factors; D000091102:YAP-Signaling Proteins; C088374:YAP1 protein, human; C482119:BRAF protein, human; D017346:Protein Serine-Threonine Kinases; D048493:Proto-Oncogene Proteins B-raf; D020930:MAP Kinase Kinase Kinases