title: The effect of peritoneal cavity saline irrigation at cesarean delivery on maternal morbidity and gastrointestinal system outcomes.
abstract: OBJECTIVE
  The objective of this study is to investigate the effect of peritoneal cavity saline irrigation during cesarean section (CS) on gastrointestinal disturbance and postoperative infectious morbidity (PIM).
  
  
  METHODS
  This prospective randomized clinic trial included 430 women who underwent elective or primary CS. The participants were randomized to either an irrigation of the abdominal cavity or the control group. The primary outcome measured was the rate of antiemetic drugs required in the postoperative period following CS. Secondary outcome measures included the rate of PIM.
  
  
  RESULTS
  Participants in both groups had similar demographic and clinical characteristics. The rate of antiemetic drugs required by patients was significantly higher in the irrigation group when compared with the control group (15.8% versus 8.4%, p = 0.018). The rate of intraoperative nausea and emesis (p ≤ 0.001) and the rate of postoperative nausea and emesis (p ≤ 0.001 and p = 0.018, respectively) were significantly higher in the irrigation group compared with the control group.
  
  
  CONCLUSIONS
  Irrigation with saline at the time of CS increases both intraoperative and postoperative nausea and emesis without any beneficial effects on PIM. Routine use of saline irrigation in the abdominal cavity does not seem to be reasonable.
authors.affiliation: a Department of Gynecology and Obstetrics , Sisli Hamidiye Etfal Training and Research Hospital , Istanbul , Turkey .
authors.forename: Osman
authors.initials: O
authors.lastname: Temizkan
authors.affiliation: a Department of Gynecology and Obstetrics , Sisli Hamidiye Etfal Training and Research Hospital , Istanbul , Turkey .
authors.forename: Osman
authors.initials: O
authors.lastname: Asıcıoglu
authors.affiliation: b Department of Gynecological Oncology , Tepecik Training and Research Hospital , Izmır , Turkey and.
authors.forename: Kemal
authors.initials: K
authors.lastname: Güngördük
authors.affiliation: c Department of Gynecology and Obstetrics , Kanuni Sultan Suleyman Training and Research Hospital , Istanbul , Turkey.
authors.forename: Berhan
authors.initials: B
authors.lastname: Asıcıoglu
authors.affiliation: a Department of Gynecology and Obstetrics , Sisli Hamidiye Etfal Training and Research Hospital , Istanbul , Turkey .
authors.forename: Pınar
authors.initials: P
authors.lastname: Yalcin
authors.affiliation: a Department of Gynecology and Obstetrics , Sisli Hamidiye Etfal Training and Research Hospital , Istanbul , Turkey .
authors.forename: Isil
authors.initials: I
authors.lastname: Ayhan
mesh_terms: D000328:Adult; D000932:Antiemetics / Q000627:therapeutic use; D002585:Cesarean Section; D004363:Drug Utilization / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology; D009325:Nausea / Q000209:etiology; D010529:Peritoneal Cavity; D020250:Postoperative Nausea and Vomiting / Q000209:etiology; D011247:Pregnancy; D011446:Prospective Studies; D012965:Sodium Chloride; D007507:Therapeutic Irrigation; D014839:Vomiting / Q000209:etiology
chemical_list: D000932:Antiemetics; D012965:Sodium Chloride
keywords: Cesarean; emesis; irrigation; nausea