title: Clinical evidence for individual animal therapy for papillomatous digital dermatitis (hairy heel wart) and infectious bovine pododermatitis (foot rot).
abstract: Data supporting individual animal therapy for papillomatous digital dermatitis (PDD) and infectious pododermatitis (IP) in cattle are available for treatment with multiple drugs in the form of randomized, prospective clinical trials conducted in naturally occurring disease with negative controls and masked subjective evaluators. In the case of PDD, these trials support the use of topical tetracycline and oxytetracycline, lincomycin, a copper-containing preparation, and a nonantimicrobial cream. In individual therapy for IP, trial evidence is available to support systemic treatment with ceftiofur, florfenicol, tulathromycin, and oxytetracycline. However, it was not available for IP standards such as penicillin G, sulfadimethoxine, and tylosin.
authors.affiliation: Department of Clinical Sciences, Kansas State University College of Veterinary Medicine, 1800 Denison Avenue, Manhattan, KS 66506, USA. Electronic address: mapley@vet.ksu.edu.
authors.forename: Michael D
authors.initials: MD
authors.lastname: Apley
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy* / Q000382:microbiology; D003612:Dairying / Q000379:methods; D058066:Digital Dermatitis / Q000188:drug therapy* / Q000382:microbiology; D055317:Evidence-Based Practice; D005260:Female; D005535:Foot Rot / Q000188:drug therapy* / Q000382:microbiology; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic / Q000662:veterinary; D014208:Treponema / Q000302:isolation & purification; D014211:Treponemal Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*
chemical_list: D000900:Anti-Bacterial Agents
keywords: Clinical trials; Foot rot; Hairy heel wart; Infectious bovine podoermatitis; Interdigital necrobacillosis; Papillomatous digital dermatitis; Susceptibility testing; Therapy