title: What does gamma coherence tell us about inter-regional neural communication?
abstract: Neural oscillations have been measured and interpreted in multitudinous ways, with a variety of hypothesized functions in physiology, information processing and cognition. Much attention has been paid in recent years to gamma-band (30-100 Hz) oscillations and synchrony, with an increasing interest in 'high gamma' (>100 Hz) signals as mesoscopic measures of inter-regional communication. The biophysical origins of the measured variables are often difficult to precisely identify, however, making their interpretation fraught with pitfalls. Here we discuss how measurements of inter-regional gamma coherence can be prone to misinterpretation and suggest strategies for deciphering the roles that synchronized oscillations across brain networks may play in neural function.
authors.affiliation: 1] The Neuroscience Institute, New York University, School of Medicine, New York, New York, USA. [2] Center for Neural Science, New York University, School of Medicine, New York, New York, USA.
authors.forename: György
authors.initials: G
authors.lastname: Buzsáki
authors.affiliation: The Neuroscience Institute, New York University, School of Medicine, New York, New York, USA.
authors.forename: Erik W
authors.identifier: 0000000150287730
authors.initials: EW
authors.lastname: Schomburg
mesh_terms: D000818:Animals; D003344:Cortical Synchronization / Q000502:physiology*; D004594:Electrophysiology / Q000379:methods* / Q000592:standards; D065818:Gamma Rhythm / Q000502:physiology*; D006801:Humans; D008564:Membrane Potentials / Q000502:physiology*; D009415:Nerve Net / Q000166:cytology / Q000502:physiology*