title: [Organization of the Drosophila melanogaster SF1 insulator and its role in transcription regulation in transgenic lines].
abstract: The SF1 insulator was found to contain a polyadenylation signal, which corresponded to the functional polyadenylation signal in embryonic S2 cells and the transgenic lines of Drosophila and bi-directional promoter that functioned in S2 cells. The studies performed did not confirm the ability of the SF1 insulator to protect expression of reporter gene white from the chromosome position effect in transgenic lines.
authors.forename: D V
authors.initials: DV
authors.lastname: Leman
authors.forename: A F
authors.initials: AF
authors.lastname: Parshikov
authors.forename: P G
authors.initials: PG
authors.lastname: Georgiev
authors.forename: O G
authors.initials: OG
authors.lastname: Maksimenko
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D055012:Chromosomal Position Effects / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000096:biosynthesis / Q000235:genetics*; D029721:Drosophila Proteins / Q000096:biosynthesis / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D005786:Gene Expression Regulation; D038101:Insulator Elements / Q000235:genetics*; D011401:Promoter Regions, Genetic; D000072260:RNA Splicing Factors; D014157:Transcription Factors / Q000096:biosynthesis / Q000235:genetics*; D014158:Transcription, Genetic
chemical_list: D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D000072260:RNA Splicing Factors; C491517:SF1 protein, Drosophila; D014157:Transcription Factors