title: Structure and biosynthetic implication of 5R-(N-acetyl-L-cysteinyl)-14S-hydroxy-dihydrokalafungin from a mutant of the actVA-ORF4 gene for actinorhodin biosynthesis in Streptomyces coelicolor A3(2).
authors.affiliation: Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan.
authors.forename: Takaaki
authors.initials: T
authors.lastname: Taguchi
authors.affiliation: Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan.
authors.forename: Tomoki
authors.initials: T
authors.lastname: Maruyama
authors.affiliation: Institute of Microbial Chemistry (BIKAKEN), Tokyo, Japan.
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Sawa
authors.affiliation: Institute of Microbial Chemistry (BIKAKEN), Tokyo, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Igarashi
authors.affiliation: National Food Research Institute, Tsukuba, Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Okamoto
authors.affiliation: Research Institute of Pharmaceutical Sciences, Musashino University, Tokyo, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Ichinose
mesh_terms: D000880:Anthraquinones / Q000378:metabolism; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D053898:Biosynthetic Pathways / Q000235:genetics*; D015394:Molecular Structure; D050505:Mutant Proteins / Q000235:genetics / Q000378:metabolism; D009285:Naphthoquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism*; D013057:Spectrum Analysis; D048372:Streptomyces coelicolor / Q000201:enzymology* / Q000235:genetics / Q000378:metabolism*; D000095622:Benzoisochromanequinones
chemical_list: D000880:Anthraquinones; D001426:Bacterial Proteins; D050505:Mutant Proteins; D009285:Naphthoquinones; C013390:actinorhodin; D000095622:Benzoisochromanequinones