title: [Structural properties and functional importance of metzincin metalloproteinases].
abstract: Here wediscuss known properties of metzincin metalloproteinases, their structure, physiological roles in the cell and potential medical uses. We also present results describing a novel extracellular metzincin metalloproteinase from Bacillus pumilus with a unique combination of properties typical for both astacins and adamalysins.
authors.forename: N P
authors.initials: NP
authors.lastname: Balaban
authors.forename: N L
authors.initials: NL
authors.lastname: Rudakova
authors.forename: M R
authors.initials: MR
authors.lastname: Sharipova
mesh_terms: D000595:Amino Acid Sequence; D001407:Bacillus / Q000201:enzymology*; D006801:Humans; D008666:Metalloendopeptidases / Q000737:chemistry / Q000378:metabolism; D045726:Metalloproteases / Q000737:chemistry* / Q000378:metabolism / Q000627:therapeutic use; D011487:Protein Conformation; D017434:Protein Structure, Tertiary; D015032:Zinc / Q000378:metabolism*
chemical_list: D045726:Metalloproteases; D008666:Metalloendopeptidases; C071288:astacin; C028220:Crotalus adamanteus proteinase II; D015032:Zinc