title: Multivariate analysis of prognostic factors for idiopathic sudden sensorineural hearing loss in children.
abstract: OBJECTIVE
  To evaluate clinical characteristics and possible associated factors of idiopathic sudden sensorineural hearing loss (ISSNHL) in children using univariate and multivariate analyses.
  
  
  METHODS
  A retrospective case series with comparisons.
  
  
  METHODS
  From January 2007 to December 2013, medical records of 37 pediatric ISSNHL patients were reviewed to assess hearing recovery rate and examine factors associated with prognosis (gender; side of hearing loss; opposite side hearing loss; treatment onset; presence of vertigo, tinnitus, and ear fullness; initial hearing threshold), using univariate and multivariate analysis, and compare them with 276 adult ISSNHL patients.
  
  
  RESULTS
  Pediatric patients comprised only 6.6% of pediatric/adult cases of ISSNHL, and those below 10 years old were only 0.7%. The overall recovery rates (complete and partial) of the pediatric and adult patients were 57.4% and 47.2%, respectively. The complete recovery rate of the pediatric group (46.6%) was higher than that of the adult group (30.8%, P = .040). According to multivariate analysis, absence of tinnitus, later onset of treatment, and higher hearing threshold at initial presentation were associated with a poor prognosis in pediatric ISSNHL.
  
  
  CONCLUSIONS
  The recovery rate of ISSNHL in pediatric patients is higher than in adults, and the presence of tinnitus and earlier treatment onset is associated with favorable outcomes.
  
  
  METHODS
  4.
authors.affiliation: Departments of Otolaryngology-Head and Neck Surgery, School of Medicine, Hanyang University, Seoul, South Korea.
authors.forename: Jae Ho
authors.initials: JH
authors.lastname: Chung
authors.affiliation: Departments of Otolaryngology-Head and Neck Surgery, School of Medicine, Hanyang University, Seoul, South Korea.
authors.forename: Seok Hyun
authors.initials: SH
authors.lastname: Cho
authors.affiliation: Departments of Otolaryngology-Head and Neck Surgery, School of Medicine, Hanyang University, Seoul, South Korea.
authors.forename: Jin Hyeok
authors.initials: JH
authors.lastname: Jeong
authors.affiliation: Departments of Otolaryngology-Head and Neck Surgery, School of Medicine, Hanyang University, Seoul, South Korea.
authors.forename: Chul Won
authors.initials: CW
authors.lastname: Park
authors.affiliation: Departments of Otolaryngology-Head and Neck Surgery, School of Medicine, Hanyang University, Seoul, South Korea.
authors.forename: Seung Hwan
authors.initials: SH
authors.lastname: Lee
mesh_terms: D000158:Acoustic Impedance Tests; D000293:Adolescent; D000328:Adult; D001301:Audiometry, Pure-Tone; D002648:Child; D003911:Dextrans / Q000008:administration & dosage*; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D003639:Hearing Loss, Sudden / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007262:Infusions, Intravenous; D007267:Injections; D007322:Instillation, Drug; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017084:Otoacoustic Emissions, Spontaneous; D010952:Plasma Substitutes / Q000627:therapeutic use; D011239:Prednisolone / Q000008:administration & dosage*; D011379:Prognosis; D020127:Recovery of Function; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D016896:Treatment Outcome; D014432:Tympanic Membrane; D055815:Young Adult
chemical_list: D003911:Dextrans; D005938:Glucocorticoids; D010952:Plasma Substitutes; D011239:Prednisolone
keywords: Hearing loss; children; sudden