title: Perturbation of parentally biased gene expression during interspecific hybridization.
abstract: Interspecific hybridization often induces epigenetic remodeling that leads to transposon activation, gene expression changes, and loss of imprinting. These genomic changes can be deleterious and contribute to postzygotic hybrid incompatibility. In Arabidopsis, loss of genomic imprinting of PHERES1 and presumed failure of Polycomb Repressive Complex contributes to seed inviability observed in A. thaliana X A. arenosa interspecific hybrids. We used this species pair to further analyze the relationship between parentally biased gene expression and postzygotic hybrid incompatibility using two A. thaliana accessions, Col-0 and C24, with differential seed survival. We found that parentally biased expression was perturbed to a similar degree in both A. thaliana hybrids for PHERES1, HDG3, and six other normally paternally expressed genes. We propose that early genome remodeling and loss of imprinting of seed development genes induces lethality in both compatible and incompatible hybrids.
authors.affiliation: The Genome Center and Section of Plant Biology, University of California Davis, Davis, California, United States of America.
authors.forename: Diana
authors.initials: D
authors.lastname: Burkart-Waco
authors.affiliation: The Genome Center and Section of Plant Biology, University of California Davis, Davis, California, United States of America.
authors.forename: Kathie
authors.initials: K
authors.lastname: Ngo
authors.affiliation: The Genome Center and Section of Plant Biology, University of California Davis, Davis, California, United States of America.
authors.forename: Meric
authors.initials: M
authors.lastname: Lieberman
authors.affiliation: The Genome Center and Section of Plant Biology, University of California Davis, Davis, California, United States of America.
authors.forename: Luca
authors.initials: L
authors.lastname: Comai
mesh_terms: D017360:Arabidopsis / Q000235:genetics*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D002678:Chimera / Q000235:genetics; D018392:Genomic Imprinting; D006824:Hybridization, Genetic; D026161:MADS Domain Proteins / Q000235:genetics / Q000378:metabolism; D012639:Seeds / Q000235:genetics / Q000254:growth & development
chemical_list: D029681:Arabidopsis Proteins; D026161:MADS Domain Proteins; C475745:PHERES1 protein, Arabidopsis