title: Differences in immune response to Porphyromonas gingivalis.
abstract: About 341 (average age of 38.0 ± 2.5 years) patients with periodontal disease were included in this study. All the patients were not treated for periodontal disease for a period of 6 months prior to this study. All the patients were not on any hormonal therapy. Antibodies to Porphyromonas gingivalis (P. gingivalis) were determined in blood serum by enzyme-linked immunosorbent assay (ELISA) method. Findings from this study suggest immune response to P. gingivalis is more effective in males than in females. Smoking and obesity tends to reduce effective immune response.
authors.affiliation: Postdoctoral, Department of Periodontology, Moscow State University of Medicine and Dentistry, Moscow, Russia, e-mail: laurel178@mail.ru.
authors.forename: Laura M
authors.initials: LM
authors.lastname: Tebloeva
authors.affiliation: Assistant Professor, Department of Periodontology, Moscow State University of Medicine and Dentistry, Moscow, Russia.
authors.forename: Zalina E
authors.initials: ZE
authors.lastname: Revazova
authors.affiliation: Assistant Professor, Department of Healthy Life for Sustainable Development (UNESCO), Moscow State University of Medicine and Dentistry, Moscow, Russia.
authors.forename: Kate G
authors.initials: KG
authors.lastname: Fabrikant
authors.affiliation: Professor, Department of Periodontology, Moscow State University of Medicine and Dentistry, Moscow, Russia.
authors.forename: Lidia A
authors.initials: LA
authors.lastname: Dmitrieva
authors.affiliation: Professor, Department of Healthy Life for Sustainable Development (UNESCO), Moscow State University of Medicine and Dentistry, Moscow, Russia.
authors.forename: Konstantin G
authors.initials: KG
authors.lastname: Gurevich
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000276:immunology; D010510:Periodontal Diseases / Q000276:immunology / Q000382:microbiology*; D010514:Periodontal Pocket / Q000276:immunology; D016966:Porphyromonas gingivalis / Q000276:immunology*; D012737:Sex Factors; D012907:Smoking / Q000276:immunology; D055815:Young Adult
chemical_list: D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M