title: Use of 18F-choline positron emission tomography/CT in high-risk prostate cancer: a case of solitary adrenal metastasis.
abstract: Computed tomography and magnetic resonance imaging detected an isolated adrenal lesion in an elderly man with high-risk prostate cancer who was undergoing radiotherapy (RT) and hormonal therapy (HT). When prostate-specific antigen (PSA) was 31.66 ng/mL, the lesion was not identified as a metastasis by 18F-choline positron emission tomography/computed tomography (18F-choline-PET/CT). When PSA was over 100 ng/mL, 18F-choline-PET/CT diagnosed the malignancy. After adrenalectomy, PSA returned to normal, and stable disease remission was obtained. This case suggests that atypical metastasis may be underdiagnosed.
authors.affiliation: Radiation Oncology Section, University of Perugia, Perugia - Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Matrone
authors.forename: Silvio
authors.initials: S
authors.lastname: Sivolella
authors.forename: Rita
authors.initials: R
authors.lastname: Bellavita
authors.forename: Luciano
authors.initials: L
authors.lastname: Casciola
authors.forename: Enrico Giuseppe
authors.initials: EG
authors.lastname: Cristallini
authors.forename: Cynthia
authors.initials: C
authors.lastname: Aristei
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000556:secondary* / Q000601:surgery; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000556:secondary* / Q000601:surgery; D000315:Adrenalectomy; D000368:Aged; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood*; D017024:Chemotherapy, Adjuvant; D002794:Choline / Q000031:analogs & derivatives*; D005462:Fluorine Radioisotopes; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D064847:Multimodal Imaging / Q000379:methods; D016609:Neoplasms, Second Primary / Q000175:diagnosis; D049268:Positron-Emission Tomography / Q000379:methods; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000473:pathology* / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed
chemical_list: D018931:Antineoplastic Agents, Hormonal; D014408:Biomarkers, Tumor; D005462:Fluorine Radioisotopes; C516370:fluoromethylcholine; D017430:Prostate-Specific Antigen; D002794:Choline