title: Relationship between decayed teeth and metabolic syndrome: data from 4716 middle-aged male Japanese employees.
abstract: BACKGROUND
  Epidemiological findings regarding the relationship between decayed teeth (DT) and metabolic syndrome (MetS) are scarce. We evaluated the relationship of DT with MetS, obesity, and MetS components in early middle-aged male Japanese employees.
  
  
  METHODS
  We cross-sectionally analyzed dental and medical health checkup results from a total of 4716 participants aged 42 or 46 years. Logistic regression models were employed to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) after adjustment for age, breakfast consumption frequency, drinking habits, smoking status, and physical activity.
  
  
  RESULTS
  Significant differences in the prevalence of MetS, obesity determined by body mass index, and the components of MetS between participating men with and without DT were detected (all P < 0.01). The adjusted OR of MetS was 1.41 (95% CI, 1.14-1.74) for those with 1 or 2 DT, and 1.66 (95% CI, 1.28-2.16) for those with ≥3 DT (P for trend = 0.01), and this significant relationship was observed even in those without periodontal pocket formation (P for trend = 0.03) or missing teeth (P for trend = 0.02). DT was significantly related to overweight/obesity and the MetS components of hypertension, dyslipidemia, and hyperglycemia, with adjusted ORs of 1.35 (95% CI, 1.19-1.53), 1.22 (95% CI, 1.07-1.39), 1.18 (95% CI, 1.03-1.34), and 1.33 (95% CI, 1.13-1.56), respectively. In addition, even in non-overweight/non-obese men, DT was found to be related to dyslipidemia and hyperglycemia, though with marginal significance (P < 0.05).
  
  
  CONCLUSIONS
  Our findings suggest that having DT is related to MetS in early middle-aged Japanese men directly and through obesity and is independent of health behaviors, periodontal condition, and tooth loss.
authors.affiliation: Department of Preventive Dentistry, Osaka University Graduate School of Dentistry.
authors.forename: Miki
authors.initials: M
authors.lastname: Ojima
authors.forename: Atsuo
authors.initials: A
authors.lastname: Amano
authors.forename: Shu
authors.initials: S
authors.lastname: Kurata
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D003731:Dental Caries / Q000453:epidemiology*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D015995:Prevalence