title: Rehabilitation after traumatic brain injury.
abstract: Traumatic brain injury (TBI) is a growing problem in the US, with significant morbidity and economic implications. This diagnosis spans a wide breath of injuries from concussion to severe TBI. Thus, rehabilitation is equally diverse in its treatment strategies targeting those symptoms that are functionally limiting with the ultimate goal of independence and community reintegration. In severe TBI, rehabilitation can be lifelong. Acute care rehabilitation focuses on emergence from coma and prognostication of recovery. Therapeutic modalities and exercise, along with pharmacologic intervention, can target long-term motor and cognitive sequelae. Complications of severe TBI that are functionally limiting and impede therapy include heterotopic ossification, agitation, dysautonomia, and spasticity. In mild TBI, most patients recover quickly but education on repeat exposure is imperative, with the implications of consecutive injuries being potentially devastating. Furthermore, rehabilitation targets lingering symptoms including sleep disturbance, visuospatial deficits, headaches, and cognitive dysfunction. As research on the entire TBI population improves, commonalities in the disease process may emerge, helping rationalize therapeutic interventions and providing more robust targets for treatment.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, MA, USA.
authors.forename: Mary Alexis
authors.initials: MA
authors.lastname: Iaccarino
authors.affiliation: Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Veterans Administration, Boston and Harvard Medical School, Boston, MA, USA.
authors.forename: Saurabha
authors.initials: S
authors.lastname: Bhatnagar
authors.affiliation: Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Massachusetts General Hospital, Brigham and Woman's Hopsital, and Harvard Medical School, Boston, MA, USA. Electronic address: rzafonte@partners.org.
authors.forename: Ross
authors.initials: R
authors.lastname: Zafonte
mesh_terms: D001930:Brain Injuries / Q000453:epidemiology / Q000503:physiopathology / Q000534:rehabilitation*; D006801:Humans; D017063:Outcome Assessment, Health Care; D020127:Recovery of Function; D016896:Treatment Outcome
keywords: Traumatic brain injury; acute rehabilitation; neurorecovery; neurorehabilitation; rehabilitation