title: Multidisciplinary structured lifestyle intervention reduces the estimated risk of cardiovascular morbidity and mortality.
abstract: BACKGROUND
  Current guidelines for prevention and treatment of cardiovascular disease (CVD) emphasise the importance of a healthy lifestyle. However, successful lifestyle intervention is proving to be a challenge for healthcare professionals.
  
  
  OBJECTIVE
  Evaluation of the effect of lifestyle intervention on cardiovascular risk factors, on reaching treatment targets and on the estimated risk of cardiovascular morbidity and mortality.
  
  
  METHODS
  The effect of a six-month multidisciplinary structured lifestyle intervention programme was assessed in 186 patients with and without a history of CVD.
  
  
  RESULTS
  Multidisciplinary structured lifestyle intervention reduced the estimated ten-year risk of cardiovascular morbidity and mortality. The relative risk reduction was similar in patients with and without a history of CVD, the absolute risk reduction was higher in patients with a history of CVD. In both groups blood pressure and body weight decreased, and the maximal work rate and maximal oxygen uptake increased significantly. Blood levels of total cholesterol and cholesterol/HDL ratio decreased significantly in patients with a history of CVD. In addition, target levels for blood pressure and physical fitness were more frequently reached in both patient groups.
  
  
  CONCLUSIONS
  Multidisciplinary structured lifestyle intervention had beneficial effects on cardiovascular risk factors. Relative risk reduction was similar in patients with and without evidence of cardiovascular disease. Follow-up is needed to see how well these effects can be maintained.
authors.forename: R L H
authors.initials: RL
authors.lastname: Sprangers
authors.forename: F
authors.initials: F
authors.lastname: Stam
authors.forename: H E C
authors.initials: HE
authors.lastname: Smid
authors.forename: C D A
authors.initials: CD
authors.lastname: Stehouwer
authors.forename: I M
authors.initials: IM
authors.lastname: Hellemans
keywords: cardiovascular disease; cardiovascular risk; lifestyle intervention; prevention; risk factor; treatment target