title: Clinical application of 100 kVp acquisition with an iterative reconstruction technique in retrospective electrocardiogram-gated thoracoabdominal aortic CT angiography.
abstract: OBJECTIVE
  To evaluate the feasibility of a 100 kVp tube voltage combined with an iterative reconstruction algorithm in retrospective electrocardiogram (ECG)-gated thoracoabdominal aortic CT angiography (CTA).
  
  
  METHODS
  Ninety-eight patients who underwent clinically indicated thoracoabdominal aortic CTA were randomly assigned to two groups: group A (n = 50) were scanned to 120 kVp and group B (n = 48) to 100 kVp. The body mass index of all included patients was <25 kg/m(2). Group A scans were reconstructed with a standard filtered back projection (FBP) algorithm, and group B scans with FBP, iDose, and non-tagged algorithms. Data comparison between groups was performed using t-test and analysis of variance.
  
  
  RESULTS
  Compared with group A, the iDose algorithm in group B yielded a higher contrast-to-noise ratio (CNR; 48.1 ± 10.1, p < 0.05), a higher signal-to-noise ratio (SNR; 13.8 ± 5.4, p < 0.05), and a lower standard deviation (SD; 30.3 ± 6.9, p < 0.05). The subjective score of iDose reconstructions from group B was significantly lower than that of FBP reconstruction from group A (p < 0.05). In group B, the non-tagged algorithm resulted in a higher CNR and a higher SNR, but a higher SD and a higher subjective score than did the iDose algorithm. The average effective dose for group B was 35.8% lower than that for group A.
  
  
  CONCLUSIONS
  A combination of a 100 kVp tube voltage and the iDose algorithm can help to improve image quality and reduce radiation dose in retrospective ECG-gated thoracoabdominal aortic CTA.
authors.affiliation: The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Jia
authors.affiliation: The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
authors.forename: D
authors.initials: D
authors.lastname: Xie
authors.affiliation: The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China.
authors.forename: K
authors.initials: K
authors.lastname: Zhu
authors.affiliation: The First Affiliated Hospital of Harbin Medical University, Harbin 150001, China. Electronic address: xxgct_417@163.com.
authors.forename: X
authors.initials: X
authors.lastname: Xiao
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D001012:Aorta, Abdominal; D001018:Aortic Diseases / Q000175:diagnosis*; D004562:Electrocardiography / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods; D036542:Tomography, Spiral Computed / Q000379:methods*