title: Selective biomineralization of Co3(PO4)2-sponges triggered by His-tagged proteins: efficient heterogeneous biocatalysts for redox processes.
abstract: We report a selective method to make functional bio-inorganic materials by mineralizing cobalt-phosphate in the presence of His-tagged enzymes. We have demonstrated that the His-tag drives the biomineralization forming sponge-like structures where both inorganic and biological elements co-localize. The bio-inorganic catalysts were re-used for several redox reaction cycles demonstrating their potential to be used in synthetic chemistry.
authors.affiliation: CIC biomaGUNE, Paseo Miramon 182, 20009, Donostia-San Sebastian, Spain. flopez.ikerbasque@cicbiomagune.es.
authors.forename: Fernando
authors.initials: F
authors.lastname: López-Gallego
authors.forename: Luis
authors.initials: L
authors.lastname: Yate
mesh_terms: D000426:Alcohol Dehydrogenase / Q000737:chemistry / Q000378:metabolism*; D055162:Biocatalysis; D003035:Cobalt / Q000737:chemistry / Q000378:metabolism*; D001411:Geobacillus stearothermophilus / Q000201:enzymology; D006639:Histidine / Q000737:chemistry / Q000378:metabolism*; D013294:Lactococcus lactis / Q000201:enzymology; D010084:Oxidation-Reduction; D010316:Particle Size; D010710:Phosphates / Q000737:chemistry / Q000378:metabolism*; D013499:Surface Properties; D015032:Zinc / Q000737:chemistry / Q000378:metabolism
chemical_list: D010710:Phosphates; D003035:Cobalt; D006639:Histidine; D000426:Alcohol Dehydrogenase; D015032:Zinc