title: Oncocytic Adenocarcinoma of the Orbit.
abstract: Oncocytic adenocarcinoma of the orbit is a rare tumor, with 1 case of nonlacrimal sac, nonlacrimal gland origin, and a poor outcome previously reported. An 85-year-old man with a 2-month history of left-sided epiphora, enlarging eyelid nodules, and diplopia in left gaze was found on imaging to have a poorly circumscribed, nodular mass of uniform radiodensity in the inferomedial orbit. Incisional biopsy revealed morphologic and immunohistochemical features of oncocytic adenocarcinoma with origin in the caruncle suspected, and CT of the neck, chest, abdomen, and pelvis showed no metastases or remote primary tumor source. Based on multidisciplinary consensus, orbital exenteration with adjuvant radiation therapy was performed, and there was no evidence of residual or recurrent tumor 2 years after treatment.
authors.affiliation: *Section of Orbital and Oculofacial Plastic Surgery, Department of Ophthalmology, and †Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.
authors.forename: Gerald J
authors.initials: GJ
authors.lastname: Harris
authors.forename: Sean
authors.initials: S
authors.lastname: Paul
authors.forename: Bryan C
authors.initials: BC
authors.lastname: Hunt
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D009915:Orbit / Q000601:surgery; D009918:Orbital Neoplasms / Q000473:pathology*; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome