title: The clinical application of 320-detector row CT in transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma.
abstract: OBJECTIVE
  To evaluate the clinical value of 320-detector row CT in transcatheter arterial chemoembolization (TACE) treatment for hepatocellular carcinoma (HCC).
  
  
  METHODS
  Sixty-four patients with HCC underwent CT perfusion scanning with a 320-detector row CT before and after TACE. With the help of built-in dual-source CT perfusion software, color perfusion images of hepatic arterial perfusion (HAP), portal vein perfusion (PVP) and hepatic arterial perfusion index (HAPI) of all HCC lesions were obtained, and the above perfusion parameters were measured on the color images. The parameters obtained after TACE were compared with those obtained before TACE, and the differences were statistically analyzed.
  
  
  RESULTS
  There were significant differences in HAP, PVP and HAPI between cancer tissues and non-cancerous tissues before TACE (P < 0.05). HCC necrotic tissues had no blood perfusion after TACE. Lower HAP and HAPI and higher PVP were observed in active cancer tissues after operation as compared with those before operation.
  
  
  CONCLUSIONS
  The 320-row CT upper abdominal one-stop examination can display the whole liver perfusion well, especially the abnormal perfusion of HCC tissues and postoperative active tissues. Angiography can display the hepatic and nutrient arteries of tumors from three dimensions, and has important guiding significance in preoperative evaluation and postoperative follow up of TACE.
authors.affiliation: Department of Radiology, Chengdu Military General Hospital, No. 270, Rongdu Avenue, Jinniu District, Chengdu, 610083, Sichuan, China.
authors.forename: Feizhou
authors.initials: F
authors.lastname: Du
authors.forename: Rui
authors.initials: R
authors.lastname: Jiang
authors.forename: Ming
authors.initials: M
authors.lastname: Gu
authors.forename: Ci
authors.initials: C
authors.lastname: He
authors.forename: Jing
authors.initials: J
authors.lastname: Guan
mesh_terms: D000328:Adult; D000368:Aged; D015901:Angiography, Digital Subtraction; D001706:Biopsy; D002166:Camptothecin / Q000008:administration & dosage; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000379:methods*; D003287:Contrast Media; D004317:Doxorubicin / Q000008:administration & dosage; D004998:Ethiodized Oil / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007479:Iopamidol; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011857:Radiographic Image Interpretation, Computer-Assisted; D015641:Radiography, Interventional; D005641:Tegafur / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D005641:Tegafur; D004998:Ethiodized Oil; D004317:Doxorubicin; D007479:Iopamidol; D002166:Camptothecin