title: Novel preparation and characterization of human hair-based nanofibers using electrospinning process.
abstract: Human hair-based biocomposite nanofibers (NFs) have been fabricated by an electrospinning technique. Aqueous keratin extracted from human hair was successfully blended with poly(vinyl alcohol) (PVA). The focus here is on transforming into keratin/PVA nanofibrous membranes and insoluble property of electrospun NFs. The resulting hair-based NFs were characterized using Fourier transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), differential scanning colorimetry (DSC), and thermogravimetric analysis (TGA). Toward the potential use of these NFs after cross-linking with various weight fractions of glyoxal, its physicochemical properties, such as morphology, mechanical strength, crystallinity, and chemical structure were investigated. Keratin/PVA ratio of 2/1 NFs with 6 wt%-glyoxal showed good uniformity in fiber morphology and suitable mechanical properties, and excellent antibacterial activity providing a potential application of hair-based NFs in biomedical field.
authors.affiliation: Department of Organic Materials & Fiber Engineering, Chonbuk National University, Jeonju 561-756, South Korea. Electronic address: wonderfulmira@jbnu.ac.kr.
authors.forename: Mira
authors.initials: M
authors.lastname: Park
authors.affiliation: Department of Chemistry, Inha University, 100 Inharo, Incheon 402-751, South Korea.
authors.forename: Hye Kyoung
authors.initials: HK
authors.lastname: Shin
authors.affiliation: Department of Organic Materials & Fiber Engineering, Chonbuk National University, Jeonju 561-756, South Korea.
authors.forename: Gopal
authors.initials: G
authors.lastname: Panthi
authors.affiliation: Department of Chemistry, Inha University, 100 Inharo, Incheon 402-751, South Korea.
authors.forename: Mohammad Mahbub
authors.initials: MM
authors.lastname: Rabbani
authors.affiliation: Department of BIN Fusion technology, Chonbuk National University, Jeonju 561-756, South Korea.
authors.forename: Al-Mahmnur
authors.initials: AM
authors.lastname: Alam
authors.affiliation: Department of BIN Fusion technology, Chonbuk National University, Jeonju 561-756, South Korea.
authors.forename: Jawun
authors.initials: J
authors.lastname: Choi
authors.affiliation: Department of Biomedical Sciences, Chonbuk National University Medical School, Jeonju 561-756, South Korea.
authors.forename: Hea-Jong
authors.initials: HJ
authors.lastname: Chung
authors.affiliation: Department of Biomedical Sciences, Chonbuk National University Medical School, Jeonju 561-756, South Korea.
authors.forename: Seong-Tshool
authors.initials: ST
authors.lastname: Hong
authors.affiliation: Department of BIN Fusion technology, Chonbuk National University, Jeonju 561-756, South Korea. Electronic address: khy@chonbuk.ac.kr.
authors.forename: Hak-Yong
authors.initials: HY
authors.lastname: Kim
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D052978:Disk Diffusion Antimicrobial Tests; D006197:Hair / Q000737:chemistry* / Q000648:ultrastructure; D006801:Humans; D007633:Keratins / Q000737:chemistry; D057139:Nanofibers / Q000737:chemistry* / Q000648:ultrastructure; D011142:Polyvinyl Alcohol / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D007633:Keratins; D011142:Polyvinyl Alcohol
keywords: Electrospinning; Keratin; Nanofibers