title: First discovery of acetone extract from cottonseed oil sludge as a novel antiviral agent against plant viruses.
abstract: A novel acetone extract from cottonseed oil sludge was firstly discovered against plant viruses including Tobacco mosaic virus (TMV), Rice stripe virus (RSV) and Southern rice black streaked dwarf virus (SRBSDV). Gossypol and β-sitosterol separated from the acetone extract were tested for their effects on anti-TMV and analysed by nuclear magnetic resonance (NMR) assay. In vivo and field trials in different geographic distributions and different host varieties declared that this extract mixture was more efficient than the commercial agent Ningnanmycin with a broad spectrum of anti-plant-viruses activity. No phytotoxic activity was observed in the treated plants and environmental toxicology showed that this new acetone extract was environmentally friendly, indicating that this acetone extract has potential application in the control of plant virus in the future.
authors.affiliation: College of Plant Protection, State Key Laboratory of Crop Stress Biology for Arid Areas, Key Laboratory of Crop Pest Integrated Pest Management on Crop in Northwestern Loess Plateau, Ministry of Agriculture, Key Laboratory of Plant Protection Resources and Pest Management, Ministry of Education, Northwest A&F University, Yangling, Shaanxi, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhao
authors.affiliation: College of Horticulture, State Key Laboratory of Crop Stress Biology for Arid Areas, Key Laboratory of Crop Pest Integrated Pest Management on Crop in Northwestern Loess Plateau, Ministry of Agriculture, Key Laboratory of Plant Protection Resources and Pest Management, Ministry of Education, Northwest A&F University, Yangling, Shaanxi, China.
authors.forename: Chaohong
authors.initials: C
authors.lastname: Feng
authors.affiliation: College of Plant Protection, State Key Laboratory of Crop Stress Biology for Arid Areas, Key Laboratory of Crop Pest Integrated Pest Management on Crop in Northwestern Loess Plateau, Ministry of Agriculture, Key Laboratory of Plant Protection Resources and Pest Management, Ministry of Education, Northwest A&F University, Yangling, Shaanxi, China.
authors.forename: Caiting
authors.initials: C
authors.lastname: Hou
authors.affiliation: College of Horticulture, State Key Laboratory of Crop Stress Biology for Arid Areas, Key Laboratory of Crop Pest Integrated Pest Management on Crop in Northwestern Loess Plateau, Ministry of Agriculture, Key Laboratory of Plant Protection Resources and Pest Management, Ministry of Education, Northwest A&F University, Yangling, Shaanxi, China.
authors.forename: Lingyun
authors.initials: L
authors.lastname: Hu
authors.affiliation: College of Horticulture, State Key Laboratory of Crop Stress Biology for Arid Areas, Key Laboratory of Crop Pest Integrated Pest Management on Crop in Northwestern Loess Plateau, Ministry of Agriculture, Key Laboratory of Plant Protection Resources and Pest Management, Ministry of Education, Northwest A&F University, Yangling, Shaanxi, China.
authors.forename: Qiaochun
authors.initials: Q
authors.lastname: Wang
authors.affiliation: College of Plant Protection, State Key Laboratory of Crop Stress Biology for Arid Areas, Key Laboratory of Crop Pest Integrated Pest Management on Crop in Northwestern Loess Plateau, Ministry of Agriculture, Key Laboratory of Plant Protection Resources and Pest Management, Ministry of Education, Northwest A&F University, Yangling, Shaanxi, China.
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Wu
mesh_terms: D000096:Acetone / Q000737:chemistry*; D000998:Antiviral Agents / Q000494:pharmacology*; D003369:Cottonseed Oil / Q000737:chemistry*; D010936:Plant Extracts / Q000494:pharmacology*; D010942:Plant Viruses / Q000187:drug effects*
chemical_list: D000998:Antiviral Agents; D003369:Cottonseed Oil; D010936:Plant Extracts; D000096:Acetone