title: Dual-phase 99mTc-MIBI imaging findings in sporadic primary hyperplasia of parathyroid glands.
abstract: Primary hyperplasia of parathyroid is uncommon and rarely documented in literatures. We report an 18-year-old female patient with hyperparathyroidism due to unifocal primary hyperplasia of parathyroid glands. Dual-phase Tc-MIBI imaging was performed for this patient. We found remarkably increased MIBI uptake in the hyperplastic lesion in early imaging and no extinction of the uptake in delayed imaging. These results suggest that the dual-phase Tc-MIBI imaging is useful in localizing the hyperfunctioning lesions of primary hyperplasia of parathyroid glands.
authors.affiliation: From the *Emergency Center, Departments of †Nuclear Medicine, and ‡Pathology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
authors.forename: Qi-Sheng
authors.initials: QS
authors.lastname: Yang
authors.forename: Chang-Yin
authors.initials: CY
authors.lastname: Wang
authors.forename: Bi-Cheng
authors.initials: BC
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000000981:diagnostic imaging; D010280:Parathyroid Glands / Q000000981:diagnostic imaging* / Q000473:pathology; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi