title: Laparoscopic myomectomy.
abstract: Uterine leiomyoma is the most common benign tumour occurring in women in the reproductive age. It is typically found during the middle and later reproductive years. The prevalence quoted in literature ranges from 20-50% based on post mortem studies. The symptoms usually reported by women with fibroids are the following: abnormal gynaecologic haemorrhage, chronic pelvic pain, dyspareunia, as well as urinary and bowel symptoms, urinary frequency or retention and, in some cases, infertility. During pregnancy, premature labor might be caused, interfering with the position of the fetus or abortion could be induced. However, only 30% of the women develop symptoms, most of them being asymptomatic. It was proved that the factors that can cause fibroids are the following: genetic, hormonal, and growth factors, especially transforming the growth factor beta (TGFb)-related cellular changes. As diagnosis tools, studies are revealing that ultrasound has been shown to be an insufficient method of myoma mapping, and magnetic resonance imaging should be preferred for surgical therapy planning. The contour of the endometrial cavity is delineated by using trans vaginal ultrasound and saline infusion hysterosonography, but hysteroscopy is the gold standard to evaluate the uterine cavity.
authors.affiliation: General Surgery Department, "Sf. Ioan" Clinical Emergency Hospital, Bucharest, Romania.
authors.forename: R A
authors.initials: RA
authors.lastname: Stoica
authors.affiliation: Endocrinology Department, Emergency Hospital Craiova, Craiova, Romania.
authors.forename: I
authors.initials: I
authors.lastname: Bistriceanu
authors.affiliation: "Bucur" Clinic of Obstetrics and Gynecology, Bucharest, Romania.
authors.forename: R
authors.initials: R
authors.lastname: Sima
authors.affiliation: General Surgery Department, "Sf. Ioan" Clinical Emergency Hospital, Bucharest, Romania.
authors.forename: N
authors.initials: N
authors.lastname: Iordache
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology; D010535:Laparoscopy; D007889:Leiomyoma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D055815:Young Adult
keywords: adhesion; fibroid; infertility; laparoscopic myomectomy