title: Reaction of arynes with sulfoxides.
abstract: A S-O bond insertion reaction of sulfoxides with arynes is reported. This reaction represents a rare instance of semipolar single bond insertion in aryne chemistry. The study of mechanism indicates that a sulfur ylide triggered by aryne is the key intermediate, which further transfers its methylene group to carbonyl compounds to give epoxides and thioethers through a sequential process.
authors.affiliation: State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University , Tianjin 300071, People's Republic of China.
authors.forename: Hong-Ying
authors.initials: HY
authors.lastname: Li
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Xing
authors.forename: Mei-Mei
authors.initials: MM
authors.lastname: Lou
authors.forename: Han
authors.initials: H
authors.lastname: Wang
authors.forename: Rui-Hua
authors.initials: RH
authors.lastname: Liu
authors.forename: Bin
authors.initials: B
authors.lastname: Wang