title: Solid variant type of serous cystadenocarcinoma of the pancreas: a case report and review of the literature.
abstract: Serous cystic neoplasms (SCN) of the pancreas are typically honeycombed microcystic masses, which are believed to be benign entity. This report describes a case of a 69-year-old man with a rare solid type of serous cystadenocarcinoma of the pancreas with liver metastases. A 6-cm well enhanced pancreatic tumor and multiple liver nodules were depicted with contrast medium on computed tomography scan. Distal pancreatectomy was performed at first operation. The cut surface of the tumor was solid and glossy appearance. Second operation of liver resection for all metastatic nodules was performed 27 months after the initial operation. The tumor cells in both the pancreas and the liver had cytoplasmic periodic acid-Schiff positive granules, which were completely digested by diastase. Eleven cases of serous cystadenocarcinoma of the pancreas have been reported in the literature. To our knowledge, this is the first case of a solid type serous cystadenocarcinoma.
authors.affiliation: Department of Gastroenterological Surgery, Chiba Cancer Center, Japan. Electronic address: okainuma@chiba-cc.jp.
authors.forename: Osamu
authors.initials: O
authors.lastname: Kainuma
authors.affiliation: Department of Gastroenterological Surgery, Chiba Cancer Center, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamamoto
authors.affiliation: Department of Gastroenterological Surgery, Chiba Cancer Center, Japan.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Cho
authors.affiliation: Department of Gastroenterological Surgery, Chiba Cancer Center, Japan.
authors.forename: Hidehito
authors.initials: H
authors.lastname: Arimitsu
authors.affiliation: Department of Gastroenterological Surgery, Chiba Cancer Center, Japan.
authors.forename: Hiroo
authors.initials: H
authors.lastname: Yanagibashi
authors.affiliation: Department of Gastroenterological Surgery, Chiba Cancer Center, Japan.
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Takiguchi
authors.affiliation: Department of Gastroenterological Surgery, Chiba Cancer Center, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Nabeya
authors.affiliation: Department of Surgical Pathology, Chiba Cancer Center, Japan.
authors.forename: Hidetada
authors.initials: H
authors.lastname: Kawana
mesh_terms: D018284:Cystadenocarcinoma, Serous / Q000235:genetics* / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Liver metastases; PAS stain; Pancreas; Serous cystadenocarcinoma; Solid type; pNET