title: Adrenal and hepatic aspergillosis in an immunocompetent patient.
abstract: Invasive aspergillosis, an infection most frequently induced by Aspergillus fumigatus and Aspergillus flavus, typically occurs in immunocompromised patients and is usually transmitted through inhalation of Aspergillus spores. As the lungs are by far the most common site involved in invasive aspergillosis and invasive aspergillosis in immunocompetent hosts is very rare, there have been a few case reports of extra-pulmonary, disseminated invasive aspergillosis in immunocompetent persons. Herein, we report a case of an adult, male, immunocompetent patient with disseminated invasive aspergillosis that successively spread from the right adrenal gland to the left hepatic lobe. The patient was successfully treated through surgical excisions of his adrenal and hepatic masses followed by voriconazole therapy. To our knowledge, this is the first case report of invasive aspergillosis affecting the adrenal glands.
authors.affiliation: From the Center for Infectious Diseases, West China Hospital, Sichuan University , Chengdu , China.
authors.forename: Liyu
authors.initials: L
authors.lastname: Chen
authors.forename: Yanbin
authors.initials: Y
authors.lastname: Liu
authors.forename: Weiya
authors.initials: W
authors.lastname: Wang
authors.forename: Kai
authors.initials: K
authors.lastname: Liu
mesh_terms: D000307:Adrenal Gland Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D000311:Adrenal Glands / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D001230:Aspergillus / Q000302:isolation & purification; D003131:Combined Modality Therapy; D006801:Humans; D007121:Immunocompetence; D008099:Liver / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery; D008107:Liver Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D008297:Male; D011859:Radiography; D065819:Voriconazole / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D065819:Voriconazole
keywords: Aspergillus; adrenal; aspergillosis; hepatic; immunocompetent; liver