title: The Effect of Trabeculectomy on Astigmatism.
abstract: OBJECTIVE
  To investigate the change in corneal astigmatism after trabeculectomy.
  
  
  METHODS
  Between January and April 2012, patients who underwent a primary trabeculectomy were enrolled in this prospective study. We measured the visual acuity, automated keratorefractometry, and the intraocular pressure preoperatively and postoperatively at 1, 3, and 6 months. Changes in astigmatism were quantified using the vector analysis described by Cravy. A Friedman test and a linear model for longitudinal measures were used to compare changes in the refraction and the intraocular pressure. A binomial test was used to compare the proportion of eyes with a shift in astigmatism with or against-the-rule.
  
  
  RESULTS
  A total of 47 eyes (47/48 patients) were included for analysis. The mean (±SD) intraocular pressure decreased from 17.5 ± 5.4 mmHg preoperatively to 9.8 ± 4.0 mmHg after 6 months (P<0.001). At this time-point, 32/47 eyes showed a shift in astigmatism with-the-rule (P=0.02), with a median difference in cylinder of +0.50 D (range, 0 to 4 D) (P=0.004). The mean (±SD) axis of the positive cylinder changed from 169 ± 148 to 135 ± 146 degrees after 6 months (P=0.12) and the mean (±SD) spherical equivalent changed from -0.47 ± 2.27 to -0.07 ± 1.93 D (P=0.15). The mean (±SD) logMAR was 0.17 ± 0.22 preoperatively and 0.14 ± 0.14 after 6 months (P=0.9).
  
  
  CONCLUSIONS
  Trabeculectomy induced a small but statistically significant shift in astigmatism with-the-rule after 6 months. The spherical equivalent did not change compared with the preoperative value. Most often, glasses will not need to be changed after trabeculectomy.
authors.affiliation: Department of Ophthalmology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Heleen
authors.initials: H
authors.lastname: Delbeke
authors.forename: Ingeborg
authors.initials: I
authors.lastname: Stalmans
authors.forename: Evelien
authors.initials: E
authors.lastname: Vandewalle
authors.forename: Thierry
authors.initials: T
authors.lastname: Zeyen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001251:Astigmatism / Q000503:physiopathology*; D017889:Exfoliation Syndrome / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D057066:Low Tension Glaucoma / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014065:Tonometry, Ocular; D014130:Trabeculectomy; D014792:Visual Acuity / Q000502:physiology