title: Novel Hormone Receptors Present in Apocrine Cystadenoma of the Eyelid.
abstract: A 53-year-old woman presented with an apocrine cystadenoma of the right upper eyelid. Histologic examination revealed proliferating epithelial cells with apocrine snouts and occasional mitotic figures. Immunohistochemical analysis revealed a Ki-67 index of 15% and positive staining for synaptophysin, chromogranin, estrogen receptor, progesterone receptor, gross cystic disease fluid protein (GCDFP)-15, and mammoglobin. The complement of positive immunomarkers in this case reinforces the importance of total excision and careful histologic assessment.
authors.affiliation: *Department of Ophthalmology; and †Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York, U.S.A.
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Brown
authors.forename: Alan H
authors.initials: AH
authors.lastname: Friedman
authors.forename: Robert G
authors.initials: RG
authors.lastname: Phelps
authors.forename: Ira J
authors.initials: IJ
authors.lastname: Bleiweiss
authors.forename: Albert Y
authors.initials: AY
authors.lastname: Wu
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D003537:Cystadenoma / Q000737:chemistry*; D005142:Eyelid Neoplasms / Q000737:chemistry*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*
chemical_list: D014408:Biomarkers, Tumor; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone