title: Development of effective connectivity in the core network for face perception.
abstract: This study measured effective connectivity within the core face network in young children using a paediatric magnetoencephalograph (MEG). Dynamic casual modeling (DCM) of brain responses was performed in a group of adults (N = 14) and a group of young children aged from 3 to 6 years (N = 15). Three candidate DCM models were tested, and the fits of the MEG data to the three models were compared at both individual and group levels. The results show that the connectivity structure of the core face network differs significantly between adults and children. Further, the relative strengths of face network connections were differentially modulated by experimental conditions in the two groups. These results support the interpretation that the core face network undergoes significant structural configuration and functional specialization between four years of age and adulthood.
authors.affiliation: Department of Cognitive Science, Macquarie University, New South Wales, Australia; Australian Research Council Centre of Excellence in Cognition and Its Disorders, Macquarie University, New South Wales, Australia.
authors.forename: Wei
authors.initials: W
authors.lastname: He
authors.forename: Marta I
authors.initials: MI
authors.lastname: Garrido
authors.forename: Paul F
authors.initials: PF
authors.lastname: Sowman
authors.forename: Jon
authors.initials: J
authors.lastname: Brock
authors.forename: Blake W
authors.initials: BW
authors.lastname: Johnson
mesh_terms: D000328:Adult; D001499:Bayes Theorem; D001921:Brain / Q000254:growth & development* / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods; D002648:Child; D002675:Child, Preschool; D005074:Evoked Potentials, Visual / Q000502:physiology; D000066499:Facial Recognition / Q000502:physiology*; D005260:Female; D006801:Humans; D015225:Magnetoencephalography / Q000379:methods; D008297:Male; D009434:Neural Pathways / Q000254:growth & development / Q000502:physiology; D010775:Photic Stimulation; D012815:Signal Processing, Computer-Assisted
keywords: childhood; cortical network; dynamic causal modeling; face processing; magnetoencephalography