title: Is there a role of adjuvant treatment for salivary duct carcinoma?
abstract: OBJECTIVE
  To determine the clinical effect of post-operative radiotheraphy and systemic chemotherapy for the treatment of salivary duct carcinoma.
  
  
  METHODS
  Retrospective review.
  
  
  METHODS
  The medical records of 26 patients treated by surgery with or without radiotheraphy and/or systemic chemotherapy for salivary duct carcinoma were retrospectively reviewed to investigate the role of post-operative adjuvant treatment for the patients' prognosis.
  
  
  RESULTS
  The overall three-year and five-year survival rates were 54 and 48.1 per cent, respectively. There was no correlation with the clinical stage and the patients' prognosis. The overall three-year survival of the patients with or without post-operative radiotheraphy was 64 and 33 per cent, respectively (p = 0.29). The overall three-year survival of the patients with or without post-operative chemotherapy was 53 and 56 per cent, respectively (p = 0.78).
  
  
  CONCLUSIONS
  Post-operative adjuvant therapy did not improve the patients' overall prognosis with salivary duct carcinoma. Developing novel treatment modalities may be necessary to improve the prognosis of this aggressive disease.
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nakashima
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: R
authors.initials: R
authors.lastname: Yasumatsu
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: S
authors.initials: S
authors.lastname: Toh
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: K
authors.initials: K
authors.lastname: Hashimoto
authors.affiliation: Department of Clinical Radiology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: M
authors.initials: M
authors.lastname: Shinoto
authors.affiliation: Department of Clinical Radiology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nakamura
authors.affiliation: Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.
authors.forename: S
authors.initials: S
authors.lastname: Komune
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D059186:Chemoradiotherapy, Adjuvant / Q000401:mortality*; D006258:Head and Neck Neoplasms / Q000628:therapy*; D006801:Humans; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D018987:Salivary Ducts; D012468:Salivary Gland Neoplasms / Q000628:therapy*; D000077195:Squamous Cell Carcinoma of Head and Neck; D015996:Survival Rate
keywords: Adjuvant treatment