title: Synthesis of pyrazoles from 1,3-diols via hydrogen transfer catalysis.
abstract: 1,3-Diols engage in ruthenium-catalyzed hydrogen transfer in the presence of alkyl hydrazines to provide 1,4-disubstituted pyrazoles. Regioselective synthesis of unsymmetrical pyrazoles from β-hydroxy ketones is also described.
authors.affiliation: Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States.
authors.forename: Daniel C
authors.initials: DC
authors.lastname: Schmitt
authors.affiliation: Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States.
authors.forename: Alexandria P
authors.initials: AP
authors.lastname: Taylor
authors.affiliation: Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States.
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Flick
authors.affiliation: Pfizer Global Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States.
authors.forename: Robert E
authors.initials: RE
authors.lastname: Kyne