title: Regulation of Cellular Response Pattern to Phosphorus Ion is a New Target for the Design of Tissue-Engineered Blood Vessel.
abstract: Regulation of cellular response pattern to phosphorus ion (PI) is a new target for the design of tissue-engineered materials. Changing cellular response pattern to high PI can maintain monocyte/macrophage survival in TEBV and the signal of increasing PI can be converted by klotho to the adenosine signals through the regulation of energy metabolism in monocytes/macrophages.
authors.affiliation: Department of Anatomy, National & Regional Engineering Laboratory of Tissue Engineering, Key Lab for Biomechanics and Tissue Engineering of Chongqing, Third Military Medical University, Chongqing, 400038, China.
authors.forename: Wen
authors.initials: W
authors.lastname: Chen
authors.affiliation: Department of Cardiology, Xinqiao Hospital, Third Military Medical University, Chongqing, 400038, China.
authors.forename: Fangjuan
authors.initials: F
authors.lastname: Wang
authors.affiliation: Department of Anatomy, National & Regional Engineering Laboratory of Tissue Engineering, Key Lab for Biomechanics and Tissue Engineering of Chongqing, Third Military Medical University, Chongqing, 400038, China.
authors.forename: Wen
authors.initials: W
authors.lastname: Zeng
authors.affiliation: Department of Anatomy, National & Regional Engineering Laboratory of Tissue Engineering, Key Lab for Biomechanics and Tissue Engineering of Chongqing, Third Military Medical University, Chongqing, 400038, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Sun
authors.affiliation: Department of Anatomy, National & Regional Engineering Laboratory of Tissue Engineering, Key Lab for Biomechanics and Tissue Engineering of Chongqing, Third Military Medical University, Chongqing, 400038, China.
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Anatomy, National & Regional Engineering Laboratory of Tissue Engineering, Key Lab for Biomechanics and Tissue Engineering of Chongqing, Third Military Medical University, Chongqing, 400038, China.
authors.forename: Mingcan
authors.initials: M
authors.lastname: Yang
authors.affiliation: Department of Anatomy, National & Regional Engineering Laboratory of Tissue Engineering, Key Lab for Biomechanics and Tissue Engineering of Chongqing, Third Military Medical University, Chongqing, 400038, China.
authors.forename: Jiansen
authors.initials: J
authors.lastname: Sun
authors.affiliation: Department of Anatomy, National & Regional Engineering Laboratory of Tissue Engineering, Key Lab for Biomechanics and Tissue Engineering of Chongqing, Third Military Medical University, Chongqing, 400038, China.
authors.forename: Yangxiao
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of Cardiology, Xinqiao Hospital, Third Military Medical University, Chongqing, 400038, China.
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Department of Anatomy, National & Regional Engineering Laboratory of Tissue Engineering, Key Lab for Biomechanics and Tissue Engineering of Chongqing, Third Military Medical University, Chongqing, 400038, China.
authors.forename: Chuhong
authors.initials: C
authors.lastname: Zhu
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000187:drug effects* / Q000502:physiology*; D008264:Macrophages / Q000187:drug effects / Q000502:physiology; D009000:Monocytes / Q000187:drug effects / Q000502:physiology; D010758:Phosphorus / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D023822:Tissue Engineering / Q000379:methods
chemical_list: D010758:Phosphorus
keywords: apoptosis; klotho; monocytes/macrophages; phosphorus ion; tissue-engineered blood vessels