title: Bariatric surgery in morbidly obese adolescents: a systematic review and meta-analysis.
abstract: Pubmed, Embase, and Cochrane were systematically reviewed for available evidence on bariatric surgery in adolescents. Thirty-seven included studies evaluated the effect of laparoscopic adjustable gastric banding (LAGB), Roux-en-Y gastric bypass (RYGB), or laparoscopic sleeve gastrectomy (LSG) in patients ≤18 years old. Fifteen of 37 studies were prospective, including one RCT. Mean body mass index (BMI) loss after LAGB was 11.6 kg/m(2) (95% CI 9.8-13.4), versus 16.6 kg/m(2) (95% CI 13.4-19.8) after RYGB and 14.1 kg/m(2) (95% CI 10.8-17.5) after LSG. Two unrelated deaths were reported after 495 RYGB procedures. All three bariatric procedures result in substantial weight loss and improvement of comorbidity with an acceptable complication rate, indicating that surgical intervention is applicable in appropriately selected morbidly obese adolescents.
authors.affiliation: Department of Surgery, Maastricht University Medical Center, and Nutrition and Toxicology Research Institute (NUTRIM), P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands, research@givan.nl.
authors.forename: Givan F
authors.initials: GF
authors.lastname: Paulus
authors.forename: Loes E G
authors.initials: LE
authors.lastname: de Vaan
authors.forename: Froukje J
authors.initials: FJ
authors.lastname: Verdam
authors.forename: Nicole D
authors.initials: ND
authors.lastname: Bouvy
authors.forename: Ton A W
authors.initials: TA
authors.lastname: Ambergen
authors.forename: L W Ernest
authors.initials: LW
authors.lastname: van Heurn
mesh_terms: D000293:Adolescent; D050110:Bariatric Surgery; D015992:Body Mass Index; D015897:Comorbidity; D005743:Gastrectomy / Q000379:methods; D015390:Gastric Bypass / Q000379:methods; D015391:Gastroplasty / Q000379:methods; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D009767:Obesity, Morbid / Q000453:epidemiology / Q000523:psychology / Q000601:surgery; D011446:Prospective Studies; D016896:Treatment Outcome; D015431:Weight Loss