title: Multimodal imaging of macular serpiginous choroidopathy from acute presentation to quiescence.
abstract: The authors report imaging findings in a case of macular serpiginous choroidopathy (MSC). Near-infrared reflectance (NIR), fundus autofluorescence (FAF), and spectral-domain optical coherence tomography (SD-OCT) were performed on a 25-year-old man presenting with decreased visual acuity and a blind spot in his left eye. Fundus examination revealed a yellow subretinal infiltrate inferior to the macula with active edges. On SD-OCT, areas of disease activity presented as a diffuse hyperreflective signal in the outer nuclear layer (ONL). Inactive lesions presented as localized thinning of the ONL. NIR allowed clear visualization of a hyperreflective junctional line between the active and inactive areas that subsequently became disrupted. FAF revealed a diffuse hypoautofluorescent halo surrounding an area of hyperautofluorescence in the acute phase and later better-defined lesions and hypoautofluorescent lesion edges.
authors.forename: Ester
authors.initials: E
authors.lastname: Carreño
authors.forename: Guillermo
authors.initials: G
authors.lastname: Fernandez-Sanz
authors.forename: Dawn A
authors.initials: DA
authors.lastname: Sim
authors.forename: Pearse A
authors.initials: PA
authors.lastname: Keane
authors.forename: Mark C
authors.initials: MC
authors.lastname: Westcott
authors.forename: Adnan
authors.initials: A
authors.lastname: Tufail
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Pavesio
mesh_terms: D000208:Acute Disease; D000328:Adult; D015862:Choroid Diseases / Q000175:diagnosis*; D004396:Coloring Agents; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D007259:Infrared Rays; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D064847:Multimodal Imaging; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green