title: Effects of two dietary fibers as part of ready-to-eat cereal (RTEC) breakfasts on perceived appetite and gut hormones in overweight women.
abstract: The effects of an enzyme-hydrolyzed arabinoxylan from wheat (AXOS) versus an intact arabinoxylan from flax (FLAX) added to a ready-to-eat cereal (RTEC) on the postprandial appetitive, hormonal, and metabolic responses in overweight women (BMI 25.0-29.9 kg/m2) were evaluated. Subsequent meal energy intake was also assessed. Two randomized, double-blind, crossover design studies were completed. For trial 1, the participants consumed the following RTEC breakfast, matched for total weight and varied in energy content: low-fiber (LF, 4 g); high-fiber (HF, 15 g) as either AXOS or FLAX. For trial 2, the participants consumed LF, HF-AXOS, and HF-FLAX RTECs but also consumed another LF breakfast that was isocaloric (LF-iso) to that of the HF breakfasts. Perceived appetite and blood samples (trial 2 only) were assessed before and after breakfast. An ad libitum lunch was offered 4 h post-breakfast. No differences in postprandial appetite responses were observed among any breakfasts in either trial. The HF-AXOS and HF-FLAX led to increased postprandial GLP-1 and peptide YY (PYY) concentrations vs. LF-iso. No differences were observed in lunch meal energy intake among breakfast meals in either trial. Collectively, these data suggest that 15 g of low molecular weight fiber added to RTECs did not affect perceived appetite or subsequent energy intake despite differences in satiety hormone signaling in overweight females.
authors.affiliation: Kellogg Company, WKKI 2 Hamblin Ave E, Battle Creek, MI 49017, USA. david.lafond@kellogg.com.|Department of Food Science and Human Nutrition, Michigan State University, 469 Wilson Road, East Lansing, MI 48824-1224, USA. david.lafond@kellogg.com.
authors.forename: David W
authors.initials: DW
authors.lastname: Lafond
authors.affiliation: Kellogg Company, WKKI 2 Hamblin Ave E, Battle Creek, MI 49017, USA. kathy.greaves@kellogg.com.
authors.forename: Kathryn A
authors.initials: KA
authors.lastname: Greaves
authors.affiliation: Biofortis Clinical Research/Midwest Center for Metabolic & Cardiovascular Research, 489 Taft Avenue, Glen Ellyn, IL 60137, USA. kmaki@mc-mcr.com.
authors.forename: Kevin C
authors.initials: KC
authors.lastname: Maki
authors.affiliation: Department of Nutrition & Exercise Physiology, University of Missouri, 307 Gwynn Hall, Columbia, MO 65211, USA. leidyh@health.missouri.edu.
authors.forename: Heather J
authors.initials: HJ
authors.lastname: Leidy
authors.affiliation: Department of Food Science and Human Nutrition, Michigan State University, 469 Wilson Road, East Lansing, MI 48824-1224, USA. dromsos@msu.edu.
authors.forename: Dale R
authors.initials: DR
authors.lastname: Romsos
mesh_terms: D000293:Adolescent; D000328:Adult; D001066:Appetite; D015992:Body Mass Index; D062408:Breakfast; D016022:Case-Control Studies; D018592:Cross-Over Studies; D004043:Dietary Fiber / Q000008:administration & dosage / Q000494:pharmacology*; D004311:Double-Blind Method; D002523:Edible Grain / Q000145:classification; D002149:Energy Intake; D005260:Female; D019597:Flax / Q000737:chemistry; D005768:Gastrointestinal Hormones / Q000097:blood*; D052216:Glucagon-Like Peptide 1 / Q000097:blood; D006801:Humans; D050177:Overweight / Q000178:diet therapy*; D019894:Peptide YY / Q000097:blood; D019518:Postprandial Period; D012527:Satiation; D014908:Triticum / Q000737:chemistry; D055815:Young Adult
chemical_list: D004043:Dietary Fiber; D005768:Gastrointestinal Hormones; D019894:Peptide YY; D052216:Glucagon-Like Peptide 1