title: Using Hyaluronic Acid for Improving Vocal Function in a Prepubescent Boy With an Atrophied Right Vocal Fold.
abstract: OBJECTIVE
  A single case study is reported of a child who underwent several surgical procedures as result of congenital grade III subglottic stenosis. The anterior aspect of the right vocal cord was damaged and underwent atrophy during one of these procedures. Now, an active 10-year-old, the patient has become increasingly aware of his vocal limitations on functional activities. Injection of hyaluronic acid into the vocal folds has been known to provide improved voice quality in adults although there are no known cases reported of this procedure in children.
  
  
  METHODS
  This article reports voice outcomes after injection of hyaluronic acid into the Reinke's space in a single case study. Voice recordings were made before, after, and 1 month after injection. The voice recordings were subject to acoustic and perceptual analysis.
  
  
  RESULTS
  Post and follow-up voice recordings demonstrate decreased jitter, shimmer, and harmonics-to-noise ratio. Perceptual evaluation indicates improved voice quality.
  
  
  CONCLUSIONS
  Injection of hyaluronic acid in children who require voice augmentation is possible and may contribute to increased vocal function and improved voice outcomes.
authors.affiliation: Speech and Language Therapy, School of Psychological Sciences and Health, University of Strathclyde, Glasgow, Scotland. Electronic address: wendy.cohen@strath.ac.uk.
authors.forename: Wendy
authors.initials: W
authors.lastname: Cohen
authors.affiliation: Ear, Nose and Throat Department, Royal Hospital for Sick Children, Yorkhill Hospitals, Glasgow, Scotland.
authors.forename: David McGregor
authors.initials: DM
authors.lastname: Wynne
mesh_terms: D001284:Atrophy / Q000188:drug therapy; D002648:Child; D006801:Humans; D006820:Hyaluronic Acid / Q000494:pharmacology / Q000627:therapeutic use*; D007829:Laryngostenosis / Q000601:surgery; D008297:Male; D011183:Postoperative Complications / Q000188:drug therapy*; D055675:Viscosupplements / Q000494:pharmacology / Q000627:therapeutic use*; D014827:Vocal Cords / Q000187:drug effects / Q000473:pathology*; D014832:Voice Disorders / Q000188:drug therapy*; D014833:Voice Quality / Q000187:drug effects
chemical_list: D055675:Viscosupplements; D006820:Hyaluronic Acid
keywords: Hyaluronic acid; Injection layrgoplasty; Laryngeal reconstruction surgery; Pediatric subglottic stenosis; Voice outcome