title: Esophageal Multichannel Intraluminal Impedance and pH Monitoring in the Evaluation of Achalasia and Gastroesophageal Reflux Disease in a Child with Down Syndrome: a Case Report.
abstract: We report the case of a rare association between achalasia and Down syndrome in a child presenting with symptoms that suggest a gastroesophageal reflux. Evaluation of the patient with 24-hour multichannel intraluminal impedance and pH recording and upper endoscopy lead to the diagnosis of achalasia. However, the persistence of the symptoms after the concurrent surgical myomectomy and fundoplication has led to repeat pH-impedance monitoring testing and endoscopy, which identified the presence of gastroesophageal reflux disease. We emphasize in this paper the importance of multichannel intraluminal impedance and pH monitoring in detecting esophageal motility disorders.
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Mihai-Mirel
authors.initials: MM
authors.lastname: Stoicescu
authors.affiliation: "Marie Sklodowska Curie" Emergency Children's Hospital, Bucharest, Romania.
authors.forename: Mihai
authors.initials: M
authors.lastname: Mocanu
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Felicia
authors.initials: F
authors.lastname: Galos
authors.affiliation: "Marie Sklodowska Curie" Emergency Children's Hospital, Bucharest, Romania.
authors.forename: Mihai
authors.initials: M
authors.lastname: Munteanu
authors.affiliation: "Marie Sklodowska Curie" Emergency Children's Hospital, Bucharest, Romania.
authors.forename: Simina
authors.initials: S
authors.lastname: Visan
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Coriolan
authors.initials: C
authors.lastname: Ulmeanu
authors.affiliation: "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Mihaela
authors.initials: M
authors.lastname: Balgradean