title: Radiosurgical options in neuro-oncology: a review on current tenets and future opportunities. Part II: adjuvant radiobiological tools.
abstract: Stereotactic radiosurgery (SRS) is currently a well-established, minimally invasive treatment for many primary and secondary tumors, especially deep-sited lesions for which traditional neurosurgical procedures were poorly satisfactory or not effective at all. The initial evolution of SRS was cautious, relying on more than 30 years of experimental and clinical work that preceded its introduction into the worldwide medical community. This path enabled a brilliant present, and the continuous pace of technological advancement holds promise for a brighter future. Part II of this review article will cover the impact of multimodal adjuvant technologies on SRS, and their input to the crucial role played by neurosurgeons, radiation oncologists and medical physicists in the management and care of fragile neuro-oncological patients.
authors.affiliation: Department of Neuroscience, University Hospital, AOUI, Verona - Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Ganau
authors.forename: Roberto Israel
authors.initials: RI
authors.lastname: Foroni
authors.forename: Massimo
authors.initials: M
authors.lastname: Gerosa
authors.forename: Giuseppe Kenneth
authors.initials: GK
authors.lastname: Ricciardi
authors.forename: Michele
authors.initials: M
authors.lastname: Longhi
authors.forename: Antonio
authors.initials: A
authors.lastname: Nicolato
mesh_terms: D015901:Angiography, Digital Subtraction; D001932:Brain Neoplasms / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery*; D056324:Diffusion Tensor Imaging; D005910:Glioma / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008577:Meningeal Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D008579:Meningioma / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery*; D064847:Multimodal Imaging / Q000379:methods; D060787:Neoplasm Grading; D059906:Neuroimaging / Q000379:methods*; D049268:Positron-Emission Tomography; D016634:Radiosurgery / Q000379:methods / Q000639:trends