title: Methods for obtaining and determination of squalene from natural sources.
abstract: Squalene is a natural dehydrotriterpenic hydrocarbon (C30H50) with six double bonds, known as an intermediate in the biosynthesis of phytosterol or cholesterol in plants or animals. We have briefly reviewed the natural sources for squalene and focused on the main methods and techniques to obtain and to determine it. Some of its applications in different fields of human activity are also mentioned.
authors.affiliation: Department of Industrial Biotechnologies, Faculty of Biotechnologies, University of Agricultural Sciences and Veterinary Medicine Bucharest, 59 Marasti, District 1, 011464 Bucharest, Romania.
authors.forename: Ovidiu
authors.initials: O
authors.lastname: Popa
authors.affiliation: Department of Industrial Biotechnologies, Faculty of Biotechnologies, University of Agricultural Sciences and Veterinary Medicine Bucharest, 59 Marasti, District 1, 011464 Bucharest, Romania.
authors.forename: Narcisa Elena
authors.initials: NE
authors.lastname: Băbeanu
authors.affiliation: Department of Industrial Biotechnologies, Faculty of Biotechnologies, University of Agricultural Sciences and Veterinary Medicine Bucharest, 59 Marasti, District 1, 011464 Bucharest, Romania.
authors.forename: Ioana
authors.identifier: 0000-0002-2960-230X
authors.initials: I
authors.lastname: Popa
authors.affiliation: Department of Physical-Chemical Analysis and Quality Control, National Institute for Chemical Pharmaceutical Research and Development, 112 Vitan, District 3, 031299 Bucharest, Romania.
authors.forename: Sultana
authors.initials: S
authors.lastname: Niță
authors.affiliation: Physical and Colloidal Chemistry, Department 1 (Fundamental Sciences), Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Street, District 2, 020956 Bucharest, Romania.
authors.forename: Cristina Elena
authors.initials: CE
authors.lastname: Dinu-Pârvu
mesh_terms: D000818:Animals; D001685:Biological Factors / Q000737:chemistry* / Q000378:metabolism; D002784:Cholesterol / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D010840:Phytosterols / Q000737:chemistry / Q000378:metabolism; D013185:Squalene / Q000737:chemistry* / Q000378:metabolism
chemical_list: D001685:Biological Factors; D010840:Phytosterols; D013185:Squalene; D002784:Cholesterol