title: Prevalence of Stable Angina in Spain. Results of the OFRECE Study.
abstract: OBJECTIVE
  The objective of the OFRECE study was to estimate the prevalence of stable angina in Spain. This prevalence is currently unknown, due to a lack of recent studies and to changes in the epidemiology and treatment of ischemic heart disease.
  
  
  METHODS
  This cross-sectional study involved a representative sample of the Spanish population aged 40 years or older, obtained via 2-stage random sampling: in the first stage, primary care physicians were randomly selected from each Spanish province, whereas in the second stage 20 people were selected from the population assigned to each physician. The prevalence was weighted by age, sex, and geographical area. Participants were classified as having angina if they met the "definite angina" criteria of the Rose questionnaire and as having confirmed angina if the angina was confirmed by a cardiologist or if they had a history of acute ischemic heart disease or revascularization.
  
  
  RESULTS
  Of the 11 831 people invited to participate, 8378 (71%) were analyzed (mean age, 59.2 years). The weighted prevalence of definite angina (Rose) was 2.6% (95% confidence interval, 2.1%-3.1%) and was higher in women (2.9%) than in men (2.2%), whereas that of confirmed angina was 1.4% (95% confidence interval, 1.0%-1.8%), without differences between men (1.5%) and women (1.3%). The prevalence of definite angina (Rose) increased with age (0.7% in patients aged 40 to 49 years and 7.1% in those aged 70 years or older), history of cardiovascular disease, and cardiovascular risk factors, except smoking.
  
  
  CONCLUSIONS
  The prevalence of definite angina (Rose) in the Spanish population aged 40 years or older was 2.6%, whereas that of confirmed angina was 1.4%. Both prevalences increased with age, cardiovascular risk factors, and cardiovascular history.
authors.affiliation: Servicio de Cardiología, Hospital Universitario de Getafe, Getafe, Madrid, Spain. Electronic address: joaquinjesus.alonso@salud.madrid.org.
authors.forename: Joaquín J
authors.initials: JJ
authors.lastname: Alonso
authors.affiliation: Instituto de Ciencias de la Salud, Universidad de A Coruña, INIBIC, A Coruña, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Muñiz
authors.affiliation: Servicio de Cardiología, Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain.
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Gómez-Doblas
authors.affiliation: Centro de Salud La Puebla de Montalbán, Toledo, Spain.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Rodríguez-Roca
authors.affiliation: Centro de Salud Villablanca, Madrid, Spain.
authors.forename: José María
authors.initials: JM
authors.lastname: Lobos
authors.affiliation: Servicio de Cardiología, Hospital Universitario Vall d'Hebron, Barcelona, Spain.
authors.forename: Gaietà
authors.initials: G
authors.lastname: Permanyer-Miralda
authors.affiliation: Servicio de Cardiología, Hospital Reina Sofía, Córdoba, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Anguita
authors.affiliation: Servicio de Cardiología, Hospital Clínico Universitario de Valencia, Valencia, Spain.
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Chorro
authors.affiliation: Servicio de Cardiología, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
authors.forename: Eulàlia
authors.initials: E
authors.lastname: Roig
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D060050:Angina, Stable / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D011795:Surveys and Questionnaires
keywords: Angina estable; Cardiopatía isquémica; Chronic coronary artery disease; Enfermedad coronaria crónica; Epidemiology; Epidemiología; Ischemic heart disease; Prevalence; Prevalencia; Stable angina