title: A novel microgel complex delivers acne medicine deep into follicles while demonstrating high patient tolerance.
abstract: Acne vulgaris is a common skin disease that is difficult to treat due to its multifactorial etiology. The presence of sebum and keratinocytes within the hair follicle often prevent medication from penetrating deep into the follicle where the causal bacteria are to be found. Medications able to penetrate into the follicle are often irritating to the skin. Recently, a technology has been developed that can penetrate sebum and deliver medication deep in the follicle while also being gentle on the skin. This novel microgel complex is therefore a critical next step in the treatment of acne and also an important tool for people who suffer from a lower quality of life due to persistent acne breakouts.
authors.forename: Jeff
authors.initials: J
authors.lastname: Wu
authors.forename: Jeannette
authors.initials: J
authors.lastname: Chantalat
authors.forename: Jue-Chen
authors.initials: JC
authors.lastname: Liu
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D003879:Dermatologic Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000627:therapeutic use; D016503:Drug Delivery Systems; D005782:Gels; D018859:Hair Follicle / Q000378:metabolism; D006801:Humans; D015603:Keratinocytes / Q000378:metabolism; D011788:Quality of Life; D012629:Sebum / Q000378:metabolism
chemical_list: D003879:Dermatologic Agents; D005782:Gels