title: Comparison of the brain development trajectory between Chinese and U.S. children and adolescents.
abstract: This current study investigated brain development of Chinese and American children and adolescents from 8 to 16 years of age using structural magnetic resonance imaging (MRI) techniques. Analyses comparing Chinese and U.S. children brain/head MR images were performed to explore similarities and differences in the trajectory of brain development between these two groups. Our results revealed regional and age differences in both brain/head morphological and tissue level development between Chinese and U.S. children. Chinese children's brains and heads were shorter, wider, and taller than those of U.S. children. There were significant differences in the gray matter (GM) and white matter (WM) intensity between the two nationalities. Development trajectories for cerebral volume, GM, and several key brain structures were also distinct between these two populations.
authors.affiliation: Department of Psychology, Institute for Mind and Brain, University of South Carolina Columbia, SC, USA ; Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University Chengdu, China.
authors.forename: Wanze
authors.initials: W
authors.lastname: Xie
authors.affiliation: Department of Psychology, Institute for Mind and Brain, University of South Carolina Columbia, SC, USA.
authors.forename: John E
authors.initials: JE
authors.lastname: Richards
authors.affiliation: Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University Chengdu, China.
authors.forename: Du
authors.initials: D
authors.lastname: Lei
authors.affiliation: Department of Human Development and Applied Psychology, Dr. Eric Jackman Institute of Child Study, University of Toronto Toronto, ON, Canada.
authors.forename: Kang
authors.initials: K
authors.lastname: Lee
authors.affiliation: Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University Chengdu, China.
authors.forename: Qiyong
authors.initials: Q
authors.lastname: Gong
keywords: Chinese children and adolescents; brain development; structural MRI