title: Radiation induced depigmentation disorder in two patients with breast cancer: Exploring a rare accompaniment.
abstract: Radiation induced depigmentation disorder is a rare accompaniment. We herein report two patients of bilateral breast cancer developing depigmentation disorder, initially confined to the radiation portal with subsequent generalization within few months of completion of whole breast radiotherapy. Both these patients had no prior history of vitiligo or other autoimmune disorder. This brief report highlights the importance of awareness of this association in appropriate decision making in susceptible patients thereby preventing this morbidity and its psychological ramifications.
authors.affiliation: Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: dr_ahitagni@yahoo.co.in.
authors.forename: Ahitagni
authors.initials: A
authors.lastname: Biswas
authors.affiliation: Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Pritee B
authors.initials: PB
authors.lastname: Chaudhari
authors.affiliation: Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Pramod Kumar
authors.initials: PK
authors.lastname: Julka
authors.affiliation: Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Goura Kishor
authors.initials: GK
authors.lastname: Rath
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000175:diagnosis* / Q000209:etiology*; D008875:Middle Aged; D011878:Radiotherapy / Q000009:adverse effects*
keywords: De-pigmentation; Radiation; Vitiligo