title: Contemporary diagnostics: sarcoma pathology update.
abstract: Sarcoma diagnosis continues to evolve as new information is discovered. Certain tumors have been downgraded (dermal leiomyosarcoma) and an atypical category designed for others. Recently entities include myxoinflammatory fibroblastic sarcoma, myoepithelioma, and pseudomyogenic hemangioendothelioma. The terms malignant fibrous histiocytoma and hemangiopericytoma are outdated. New immunostains (STAT6, SOX10, ERG) add diagnostic specificity, and new risk assessment models are described for sarcomas where grading and staging has failed to provide adequate prognosis.
authors.affiliation: Perlman School of Medicine, University of Pennsylvania, Chair of Pathology, Pennsylvania Hospital of the University of Pennsylvania Health System, Philadelphia, Pennsylvania; Pennsylvania Hospital of the University of Pennsylvania Health System, Philadelphia, Pennsylvania.
authors.forename: John S J
authors.initials: JS
authors.lastname: Brooks
authors.forename: Solomon
authors.initials: S
authors.lastname: Lee
mesh_terms: D006801:Humans; D018570:Risk Assessment; D012509:Sarcoma / Q000175:diagnosis* / Q000473:pathology*
keywords: immunohistochemistry; new entities; new markers; risk assessment; sarcoma