title: Aripiprazole-Induced Hypoprolactinemia in an Adult Male with First-Episode Psychosis.
abstract: Aripiprazole is an atypical antipsychotic that acts as a partial agonist at dopamine D2 receptors. Compared to other atypical antipsychotics, aripiprazole has less metabolic side effects and is less likely to increase prolactin. Moreover, it has been shown to have a unique prolactin lowering effect. While aripiprazole has been associated with subnormal prolactin levels in children, no documented cases of hypoprolactinemia in adults exist thus far. Here we report a case of aripiprazole-induced hypoprolactinemia in an adult male with first-episode psychosis, and the possible effects of abnormally low prolactin are discussed.
authors.forename: Alanna J
authors.initials: AJ
authors.lastname: Propst
authors.forename: G Eric
authors.initials: GE
authors.lastname: Jarvis
authors.forename: Howard C
authors.initials: HC
authors.lastname: Margolese
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D000068180:Aripiprazole / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011388:Prolactin / Q000172:deficiency*; D011618:Psychotic Disorders / Q000188:drug therapy*
chemical_list: D014150:Antipsychotic Agents; D000068180:Aripiprazole; D011388:Prolactin
keywords: Aripiprazole; Hypoprolactinemia; Prolactin; Psychosis