title: Bacterial etiology and antibiotic susceptibility pattern of diabetic foot infections in Tabriz, Iran.
abstract: OBJECTIVE
  The aim of this study was to investigate anaerobic and aerobic bacteria profile and determination of antibiotic susceptibility pattern in aerobic bacteria.
  
  
  METHODS
  Specimens were cultured using optimal aerobic and anaerobic microbiological techniques. Identification of bacterial isolates was performed by standard microbiological methods and antibiotic susceptibility testing was performed according to the guidelines of Clinical and Laboratory Standards Institute (CLSI).
  
  
  RESULTS
  92 bacterial strains were isolated from 60 samples of diabetic foot ulcers. Predominant aerobic bacteria isolated from these infections were S. aureus (28%) followed by Enterobacteriaceae family (24%) including Escherichia coli (15%), Citrobacter spp. (4%), Enterobacter spp. (4%), and coagulase-negative Staphylococcus spp. (17%), Enterococcus spp. (15%), Pseudomonas aeruginosa (7%) and Acinetobacter spp. (4%). No Clostridium spp. were isolated and 4% Bacteroides fragilis obtained from anaerobic culture. All Gram-positive isolates were susceptible to linezolid while all Enterobacteriaceae showed sensitivity to imipenem.
  
  
  CONCLUSIONS
  Most of DFIs specimens were poly microbial infection and predominant bacteria were S. aureus and B. fragilis. These wounds may require use of combined antimicrobial therapy for initial management.
authors.affiliation: Research Center of Infectious and Tropical Disease, Tabriz University of Medical Sciences, Tabriz, Iran ; Department of Bacteriology and Virology, School of Medicine, Tabriz University of Medical Sciences, Iran.
authors.forename: Mohammad Taghi
authors.initials: MT
authors.lastname: Akhi
authors.affiliation: Department of Bacteriology and Virology, School of Medicine, Tabriz University of Medical Sciences, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Ghotaslou
authors.affiliation: Paramedical Faculty, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Asgharzadeh
authors.affiliation: Research Center of Infectious and Tropical Disease, Tabriz University of Medical Sciences, Tabriz, Iran.
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Varshochi
authors.affiliation: Department of Bacteriology and Virology, School of Medicine, Tabriz University of Medical Sciences, Iran.
authors.forename: Tahereh
authors.initials: T
authors.lastname: Pirzadeh
authors.affiliation: Department of Bacteriology and Virology, School of Medicine, Tabriz University of Medical Sciences, Iran.
authors.forename: Mohammad Yousef
authors.initials: MY
authors.lastname: Memar
authors.affiliation: Department of Bacteriology and Virology, School of Medicine, Tabriz University of Medical Sciences, Iran.
authors.forename: Abed
authors.initials: A
authors.lastname: Zahedi Bialvaei
authors.affiliation: Department of Bacteriology and Virology, School of Medicine, Tabriz University of Medical Sciences, Iran.
authors.forename: Hasan
authors.initials: H
authors.lastname: Seifi Yarijan Sofla
authors.affiliation: Department of Bacteriology and Virology, School of Medicine, Tabriz University of Medical Sciences, Iran.
authors.forename: Naser
authors.initials: N
authors.lastname: Alizadeh
keywords: anaerobic bacteria; antibiotic susceptibility pattern; diabetic foot infections