title: [Clinical considerations in the interpretation of elevated troponin levels].
abstract: The essential role of cardiac troponin (cTn) in the diagnosis of acute myocardial infarction has led to the development of high-sensitivity assays, which are able to detect very small amounts of myocardial necrosis. However, although elevated blood levels of cTn indicate myocardial injury, they do not provide a causal explanation. The differential diagnosis of minor elevations of the cTn-level is broad and includes both acute and chronic cardiac and non-cardiac conditions. The purpose of this paper is to review common causes of elevated cTn-levels in daily clinical practice.
authors.affiliation: Medicinsk Forskningsafdeling, Odense Universitetshospital, Svendborg Sygehus, Valdemarsgade 53, 5700 Svendborg. dragana.rujic@rsyd.dk.
authors.forename: Dragana
authors.initials: D
authors.lastname: Rujic
authors.forename: Manan
authors.initials: M
authors.lastname: Pareek
authors.forename: Gro
authors.initials: G
authors.lastname: Egholm
authors.forename: Kristian
authors.initials: K
authors.lastname: Thygesen
mesh_terms: D015415:Biomarkers / Q000097:blood* / Q000378:metabolism; D003937:Diagnosis, Differential; D006331:Heart Diseases / Q000175:diagnosis; D006801:Humans; D009203:Myocardial Infarction / Q000145:classification / Q000175:diagnosis*; D011655:Pulmonary Embolism / Q000175:diagnosis; D051437:Renal Insufficiency / Q000175:diagnosis; D012680:Sensitivity and Specificity; D018805:Sepsis / Q000175:diagnosis; D020521:Stroke / Q000175:diagnosis; D014336:Troponin / Q000097:blood* / Q000378:metabolism
chemical_list: D015415:Biomarkers; D014336:Troponin