title: Predictors and Moderators of Clinical Outcomes in Adolescents with Severe Mental Disorders After an Assertive Community Treatment.
abstract: Previous studies have shown that stressful life events (SLEs), gender, social functioning and pretreatment severity are some of the predictors and/or moderators of treatment outcome in psychiatric care. The current study explored the effect of these predictors and moderators on the treatment outcome related to assertive community treatment (ACT) proposed to young people with severe mental disorders. 98 patients were assessed for externalizing and emotional difficulties, at admission and then at discharge of an ACT. Analyses revealed significant improvements in terms of symptomatology. In particular, regression analyses showed that pretreatment severity is a significant predictor of the outcome on emotional symptoms and is moderated by SLE on the outcome on externalizing symptoms. Furthermore, higher social functioning proved to predict better outcome on externalizing symptoms. Our results further evidence that these factors can explain inter-individual differences in outcome related to ACT. The theoretical and clinical implications of these results are discussed.
authors.affiliation: Research Unit, University Psychiatric Service for Child and Adolescent (UPSCA), Department of Psychiatry (DP), University Hospital (CHUV), Rue du Bugnon 25A, 1011, Lausanne, Switzerland. Sebastien.Urben@chuv.ch.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Urben
authors.affiliation: Mobile Team for Adolescent, University Psychiatric Service for Child and Adolescent (UPSCA), Department of Psychiatry (DP), University Hospital (CHUV), Lausanne, Switzerland.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Baier
authors.affiliation: Research Unit, University Psychiatric Service for Child and Adolescent (UPSCA), Department of Psychiatry (DP), University Hospital (CHUV), Rue du Bugnon 25A, 1011, Lausanne, Switzerland.
authors.forename: Gregory
authors.initials: G
authors.lastname: Mantzouranis
authors.affiliation: Mobile Team for Adolescent, University Psychiatric Service for Child and Adolescent (UPSCA), Department of Psychiatry (DP), University Hospital (CHUV), Lausanne, Switzerland.
authors.forename: Eva
authors.initials: E
authors.lastname: Pigois
authors.affiliation: Mobile Team for Adolescent, University Psychiatric Service for Child and Adolescent (UPSCA), Department of Psychiatry (DP), University Hospital (CHUV), Lausanne, Switzerland.
authors.forename: Caroline
authors.initials: C
authors.lastname: Graap
authors.affiliation: Mobile Team for Adolescent, University Psychiatric Service for Child and Adolescent (UPSCA), Department of Psychiatry (DP), University Hospital (CHUV), Lausanne, Switzerland.
authors.forename: Fabienne
authors.initials: F
authors.lastname: Dutoit
authors.affiliation: Mobile Team for Child and Adolescent, Psychiatric and Psychotherapeutic Service for Child and Adolescent, Nant Foundation, Aigle, Switzerland.
authors.forename: Mélanie
authors.initials: M
authors.lastname: Cherix-Parchet
authors.affiliation: Mobile Team for Child and Adolescent, Psychiatric Service for Child and Adolescent, Department of Psychiatry (DP), University Hospital (CHUV), Yverdon, Switzerland.
authors.forename: Coralie
authors.initials: C
authors.lastname: Henz
authors.affiliation: Mobile Team for Adolescent, University Psychiatric Service for Child and Adolescent (UPSCA), Department of Psychiatry (DP), University Hospital (CHUV), Lausanne, Switzerland.
authors.forename: Aymeric
authors.initials: A
authors.lastname: Faucherand
authors.affiliation: Mobile Team for Adolescent, University Psychiatric Service for Child and Adolescent (UPSCA), Department of Psychiatry (DP), University Hospital (CHUV), Lausanne, Switzerland.
authors.forename: Esperanza
authors.initials: E
authors.lastname: Senent
authors.affiliation: Mobile Team for Adolescent, University Psychiatric Service for Child and Adolescent (UPSCA), Department of Psychiatry (DP), University Hospital (CHUV), Lausanne, Switzerland.
authors.forename: Laurent
authors.initials: L
authors.lastname: Holzer
mesh_terms: D000293:Adolescent; D016497:Adolescent Health Services; D003156:Community Mental Health Services; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D012720:Severity of Illness Index; D016896:Treatment Outcome
keywords: Adolescents; Assertive community treatment; Moderation effect; Pretreatment severity; Psychiatric disorders; Stressful life events; Treatment outcome