title: [Improving cystic fibrosis survival as a result of management in a specialized center with 10-year follow-up].
abstract: BACKGROUND
  Cystic fibrosis (CF), the most common genetic disease among whites, is a multisystem disease that requires a coordinated multidisciplinary approach to get better results regarding survival and quality of life. This is why a Cystic Fibrosis Center (CFC) was held in Mendoza, Argentina, with the assumption that the organization and management of CF, according to international standards would improve survival.
  
  
  METHODS
  106 patients with CF have been evaluated since 1975 in this Center. Patients were grouped for follow-up monitoring as the 1999, 2002, 2005 and 2008 cohort studies. The chi-square test was used to compare survival rates and the nonparametric Mann-Whitney test was used to calculate the median age of the population.
  
  
  RESULTS
  In 2008, survival at 17 years old was 80% compared with 45% for the same age in 1999 (p < 0,001). The median age of the total CF population increased from 4 (1985) to 12 years old (2008) (p < 0,003).
  
  
  CONCLUSIONS
  A multidisciplinary standardized approach of this condition in a CF Center can significantly increase survival.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Lentini N
authors.forename: Adriana
authors.initials: A
authors.lastname: López-Millán
authors.forename: Ana María
authors.initials: AM
authors.lastname: Lores L
authors.forename: María Rosa
authors.initials: MR
authors.lastname: Pesciullesi B
authors.forename: Leonor María
authors.initials: LM
authors.lastname: Ituarte R
authors.forename: Teresa Beatriz
authors.initials: TB
authors.lastname: Viera C
mesh_terms: D000293:Adolescent; D000328:Adult; D001118:Argentina; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000401:mortality / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D033183:Interdisciplinary Communication; D008297:Male; D011788:Quality of Life; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D015996:Survival Rate; D055815:Young Adult