title: MEMS: Enabled Drug Delivery Systems.
abstract: Drug delivery systems play a crucial role in the treatment and management of medical conditions. Microelectromechanical systems (MEMS) technologies have allowed the development of advanced miniaturized devices for medical and biological applications. This Review presents the use of MEMS technologies to produce drug delivery devices detailing the delivery mechanisms, device formats employed, and various biomedical applications. The integration of dosing control systems, examples of commercially available microtechnology-enabled drug delivery devices, remaining challenges, and future outlook are also discussed.
authors.affiliation: Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, 1042 Downey Way DRB-140, Los Angeles, CA, 90089-1111, USA.
authors.forename: Angelica
authors.initials: A
authors.lastname: Cobo
authors.affiliation: Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, 1042 Downey Way DRB-140, Los Angeles, CA, 90089-1111, USA.
authors.forename: Roya
authors.initials: R
authors.lastname: Sheybani
authors.affiliation: Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, 1042 Downey Way DRB-140, Los Angeles, CA, 90089-1111, USA.|Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, 3651 Watt Way VHE-602, Los Angeles, CA, 90089-0241, USA.
authors.forename: Ellis
authors.initials: E
authors.lastname: Meng
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design / Q000295:instrumentation / Q000379:methods; D006801:Humans; D055617:Micro-Electrical-Mechanical Systems / Q000295:instrumentation* / Q000379:methods*; D055616:Microtechnology / Q000295:instrumentation / Q000379:methods
keywords: drug delivery; microelectromechanical systems; micropumps