title: Steps to diagnosis of a case of surreptitious intake of one of the newer direct oral anticoagulants: a case report and literature review.
abstract: Little is known about the effects of newer oral anticoagulants on various coagulation factors. When presented with a case of intentional or suspected overdose with an abnormal coagulation profile, it is imperative to have a working diagnostic algorithm to narrow the cause to a specific drug or drug class. This may become more crucial and time sensitive when dealing with a case of acute hemorrhage. Here we discuss the first reported case of what appears to be a surreptitious intake of newer oral anticoagulants and the steps leading to the diagnosis.
authors.affiliation: aDivision of Hematology/Oncology bDivision of Pathology, College of Medicine, University of Florida, Gainesville Florida cDepartment of Pathology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
authors.forename: Lakshmikanth
authors.initials: L
authors.lastname: Katragadda
authors.forename: Martina C
authors.initials: MC
authors.lastname: Murphy
authors.forename: Neil S
authors.initials: NS
authors.lastname: Harris
authors.forename: Gloria
authors.initials: G
authors.lastname: Wilkerson
authors.forename: Lindsay A L
authors.initials: LA
authors.lastname: Bazydlo
authors.forename: Marc S
authors.initials: MS
authors.lastname: Zumberg
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage / Q000633:toxicity*; D062787:Drug Overdose / Q000175:diagnosis*; D005260:Female; D006801:Humans; D000069552:Rivaroxaban / Q000008:administration & dosage / Q000633:toxicity*
chemical_list: D000925:Anticoagulants; D000069552:Rivaroxaban