title: Early cervical cancer impact of peritoneal vaginoplasty combined with laparoscopic radical hysterectomy improved sexual function.
abstract: OBJECTIVE
  We investigated the impact of laparoscopic radical hysterectomy (LRH) in combination with peritoneal vaginoplasty (PV) in improving sexual function after radical hysterectomy (RH) in patients with early cervical cancer.
  
  
  METHODS
  A total of 79 patients with early-stage cervical cancer younger than 45 years were assigned to receive LRH in combination with PV (the LRH-PV group; n = 31) or LRH alone (the LRH group; n = 48). Other 40 healthy females were selected as controls (the control group). The sexual function was assessed with Female Sexual Functioning Index (FSFI). The FSFI scores and sexual function in the postoperative 1 year were compared between the LRH-PV and LRH groups, LRH-PV and control groups, and LRH and control groups, respectively.
  
  
  RESULTS
  Patients with LRH-PV showed significantly higher scores in sexual satisfaction, lubrication, pain, and total score than those with LRH alone (P < 0.05) but were not statistically different in scores regarding sexual desire, arousal, and orgasm (P > 0.05). Healthy controls showed the highest in total scores and 6 domains among all subjects. In addition, the FSFI total scores in the LRH-PV group, LRH group, and LRH-PV + LRH group were significantly decreased compared with the control (P < 0.05).
  
  
  CONCLUSIONS
  Peritoneal vaginoplasty to lengthen the vagina improves sexual function of patients with early cervical cancer receiving LRH in sexual satisfaction, lubrication, and pain.
authors.affiliation: *Department of Gynecology and Obstetrics, The First Affiliated Hospital, and †Department of Infertility and Sexual Medicine, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Shu-Qin
authors.initials: SQ
authors.lastname: Chen
authors.forename: Ling-Zhi
authors.initials: LZ
authors.lastname: Kong
authors.forename: Hong-Ye
authors.initials: HY
authors.lastname: Jiang
authors.forename: Li
authors.initials: L
authors.lastname: Fan
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.forename: Shu-Zhong
authors.initials: SZ
authors.lastname: Yao
mesh_terms: D000328:Adult; D001143:Arousal; D016022:Case-Control Studies; D004414:Dyspareunia / Q000209:etiology / Q000517:prevention & control; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects; D010535:Laparoscopy; D008875:Middle Aged; D009948:Orgasm; D012735:Sexual Dysfunction, Physiological / Q000209:etiology / Q000503:physiopathology* / Q000517:prevention & control; D019529:Sexuality; D011795:Surveys and Questionnaires; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*; D014621:Vagina / Q000601:surgery*