title: Recency, repetition, and the multidimensional basis of recognition memory.
abstract: Recency and repetition are two factors that have large effects on human memory performance. One way of viewing the beneficial impact of these variables on recognition memory is to assume that both factors modulate a unidimensional memory trace strength. Although previous functional neuroimaging studies have indicated that recency and repetition may modulate similar brain structures, particularly in the region of the inferior parietal cortex, there is extensive behavioral evidence that human subjects can make independent and accurate recognition memory judgments about both an item's recency and its frequency. In the present study, we used fMRI to examine patterns of brain activity during recognition memory for auditory-verbal stimuli that were parametrically and orthogonally manipulated in terms of recency and number of repetitions. We found in a continuous recognition paradigm that the lateral inferior parietal cortex, a region that has previously been associated with recollective forms of memory, is highly sensitive to recency but not repetition. In a multivariate analysis of whole-brain activation patterns, we found orthogonal components that dissociated recency and repetition variables, indicating largely independent neural bases underlying these two factors. The results demonstrate that although both recency and repetition dramatically improve recognition memory performance, the neural bases for this improvement are dissociable, and thus are difficult to explain in terms of access to a unitary memory trace.
authors.affiliation: Rotman Research Institute, Baycrest University of Toronto, Psychology, Toronto, Ontario M6A 2E1, Canada bbuchsbaum@research.baycrest.org.
authors.forename: Bradley R
authors.identifier: http://orcid.org/0000-0002-1108-4866
authors.initials: BR
authors.lastname: Buchsbaum
authors.affiliation: Rotman Research Institute, Baycrest University of Toronto, Psychology, Toronto, Ontario M6A 2E1, Canada.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Lemire-Rodger
authors.affiliation: Rotman Research Institute, Baycrest University of Toronto, Psychology, Toronto, Ontario M6A 2E1, Canada.
authors.forename: Ashley
authors.initials: A
authors.lastname: Bondad
authors.affiliation: Rotman Research Institute, Baycrest University of Toronto, Psychology, Toronto, Ontario M6A 2E1, Canada.
authors.forename: Alexander
authors.initials: A
authors.lastname: Chepesiuk
mesh_terms: D000328:Adult; D001931:Brain Mapping; D005260:Female; D006801:Humans; D008297:Male; D010296:Parietal Lobe / Q000502:physiology*; D021641:Recognition, Psychology; D060865:Repetition Priming; D013997:Time Factors; D014706:Verbal Learning
keywords: fMRI; memory; parietal; recency; recognition; repetition