title: Intraosseous haemangioma: semantic and medical confusion.
abstract: The literature is rich in case reports of intraosseous haemangioma, although most of these are actually cases of venous or capillary malformations. To illustrate this confusion in terminology, we present three cases of slow-flow vascular malformations misnamed as intraosseous haemangioma. A retrospective study of children diagnosed with intraosseous haemangioma was conducted. Clinical and radiological data were evaluated. Histopathological examinations and immunohistochemical studies were redone by three independent pathologists to classify the lesions according to the International Society for the Study of Vascular Anomalies (ISSVA) and World Health Organization (WHO) classifications. Three children who had presented with jaw haemangiomas were identified. Computed tomography scan patterns were not specific. All tumours were GLUT-1-negative and D2-40-negative. The lesions were classified as central haemangiomas according to the WHO, and as slow-flow malformations according to the ISSVA. The classification of vascular anomalies is based on clinical, radiological, and histological differences between vascular tumours and malformations. Based on this classification, the evolution of the lesion can be predicted and adequate treatment applied. The binary ISSVA classification is widely accepted and should be applied for all vascular lesions.
authors.affiliation: APHP, Hôpital Necker Enfants Malades, Service de Chirurgie Maxillo-faciale et Plastique Pédiatrique, Paris, France; Université Paris Descartes, Paris, France; INSERM, UMRS 1138, Oral and Molecular Pathology, Centre de Recherche des Cordeliers, 75006 Paris, France; APHP, CRMR des Malformations Rares de la Face et de la Cavité Buccale, 75015 Paris, France. Electronic address: natacha.kadlub@gmail.com.
authors.forename: N
authors.initials: N
authors.lastname: Kadlub
authors.affiliation: APHP, Hôpital d'Enfants Armand Trousseau, Service de Cytologie et Pathologie, Paris, France; Université Paris 6, Faculté de Médecine Pierre et Marie Curie, Paris, France.
authors.forename: L
authors.initials: L
authors.lastname: Dainese
authors.affiliation: APHP, Hôpital d'Enfants Armand Trousseau, Service de Cytologie et Pathologie, Paris, France; Université Paris 6, Faculté de Médecine Pierre et Marie Curie, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Coulomb-L'Hermine
authors.affiliation: Université Paris Descartes, Paris, France; APHP, Hôpital Necker Enfants Malades, Service de Cytologie et Pathologie, Paris, France.
authors.forename: L
authors.initials: L
authors.lastname: Galmiche
authors.affiliation: APHP, Hôpital Necker Enfants Malades, Service de Chirurgie Maxillo-faciale et Plastique Pédiatrique, Paris, France; APHP, CRMR des Malformations Rares de la Face et de la Cavité Buccale, 75015 Paris, France.
authors.forename: V
authors.initials: V
authors.lastname: Soupre
authors.affiliation: Université Paris 6, Faculté de Médecine Pierre et Marie Curie, Paris, France; APHP, Hôpital d'Enfants Armand Trousseau, Service d'Imagerie Médicale, Paris, France.
authors.forename: H Ducou
authors.initials: HD
authors.lastname: Lepointe
authors.affiliation: APHP, Hôpital Necker Enfants Malades, Service de Chirurgie Maxillo-faciale et Plastique Pédiatrique, Paris, France; Université Paris Descartes, Paris, France; INSERM, UMRS 1138, Oral and Molecular Pathology, Centre de Recherche des Cordeliers, 75006 Paris, France; APHP, CRMR des Malformations Rares de la Face et de la Cavité Buccale, 75015 Paris, France.
authors.forename: M-P
authors.initials: MP
authors.lastname: Vazquez
authors.affiliation: APHP, Hôpital Necker Enfants Malades, Service de Chirurgie Maxillo-faciale et Plastique Pédiatrique, Paris, France; Université Paris Descartes, Paris, France; INSERM, UMRS 1138, Oral and Molecular Pathology, Centre de Recherche des Cordeliers, 75006 Paris, France; APHP, CRMR des Malformations Rares de la Face et de la Cavité Buccale, 75015 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Picard
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006391:Hemangioma / Q000145:classification*; D006801:Humans; D007223:Infant; D007573:Jaw Neoplasms / Q000145:classification*; D008297:Male; D012189:Retrospective Studies; D012886:Skull / Q000002:abnormalities*; D013131:Spine / Q000002:abnormalities*; D009626:Terminology as Topic; D054079:Vascular Malformations / Q000145:classification*
keywords: ISSVA; WHO; angioma; capillary malformation; central haemangioma; haemangioma; intraosseous haemangioma; jaw tumours; venous malformation