title: Body mass index and gonadotropin hormones (LH & FSH) associate with clinical symptoms among women with polycystic ovary syndrome.
abstract: To evaluate the relevance of body mass index (BMI), luteinizing hormone (LH), follicle-stimulating hormone (FSH) and LH/FSH ratio with clinical symptoms in polycystic ovary syndrome (PCOS) women.
  
  
  METHODS
  We reviewed the medical records of all women visited in the PCOS Clinic of Babol (Iran) from 2008 to 2012. A retrospective cross-sectional study was conducted on 175 PCOS women; aged 18-38 years diagnosed based on the Rotterdam criteria. Among the PCOs women, the prevalence of oligomenorrhea, acne, and hirsutism were found to be 92.0%, 31.4%, and 78.9%, respectively. Positive finding of polycystic ovaries was observed in 89.1% of PCOS women with by using sonography. A total of 69.2% overweight/obesity patients had polycystic ovary morphology on ultrasound image. Compared with non- overweight/obesity, the adjusted OR of PCOS women for sonographic view of polycystic ovaries was 4.33 (95% CI, 1.42-13.15, p=0.001), Nevertheless, the adjusted odds ratio (OR) showed no significant associations between LH, FSH, and LH/FSH ratio with clinical symptoms in these women. The findings of this study indicated that the overweight/obese women with PCOS are at an increased risk for sonographic view of polycystic ovaries. Therefore, it is suggested that successful weight loss is the most effective method of restoring ovulation, menstruation that should be used as major advice in obese PCOS patients.
authors.forename: Seddigheh
authors.initials: S
authors.lastname: Esmaeilzadeh
authors.affiliation: Fatemezahra Infertility and Reproductive Health Research Center Babol University of Medical Science, Babol, Iran. maryam.ghanbariandarieh@gmail.com.
authors.forename: Maryam Ghanbari
authors.initials: MG
authors.lastname: Andarieh
authors.forename: Reza
authors.initials: R
authors.lastname: Ghadimi
authors.forename: Mouloud Agajani
authors.initials: MA
authors.lastname: Delavar
mesh_terms: D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D007492:Iran / Q000453:epidemiology; D007986:Luteinizing Hormone / Q000097:blood*; D016017:Odds Ratio; D010053:Ovary / Q000000981:diagnostic imaging; D050177:Overweight / Q000097:blood / Q000453:epidemiology*; D011085:Polycystic Ovary Syndrome / Q000097:blood* / Q000000981:diagnostic imaging / Q000453:epidemiology*; D012189:Retrospective Studies; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone