title: Oral manifestations as an early clinical sign of acute myeloid leukaemia: a case report.
abstract: Leukaemia is the most common malignancy in children and one of the most common malignancies in young adults. Acute myeloid leukaemia is often associated with early oral manifestations. The purpose of this study is to report the case of a 49-year-old male with spontaneous gingival bleeding for over two years with undiagnosed leukaemia. Haematological investigation was instigated and on referral to the Haematology Department at Dunedin Public Hospital, the diagnosis of an acute myeloid leukaemia was confirmed. Since oral lesions can be one of the early events of acute myeloid leukaemia, they may be considered as an important diagnostic indicator for oral health practitioners, and their roles in diagnosing and treating such patients.
authors.affiliation: Department of Oral Diagnostic and Surgical Sciences, School of Dentistry, The University of Otago, Dunedin, New Zealand.
authors.forename: G
authors.initials: G
authors.lastname: Guan
authors.forename: N
authors.initials: N
authors.lastname: Firth
mesh_terms: D003937:Diagnosis, Differential; D055088:Early Detection of Cancer; D005884:Gingival Hemorrhage / Q000175:diagnosis*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010198:Pancytopenia / Q000175:diagnosis
keywords: Acute myeloid leukaemia; leukaemia; oral manifestations; spontaneous bleeding