title: Nothing About Us Without Us? A Comparison of Adolescent and Adult Health-State Values for the Child Health Utility-9D Using Profile Case Best-Worst Scaling.
abstract: The main objective of this study was to compare and contrast adolescent and adult values for the Child Health Utility-9D (CHU9D), a new generic preference-based measure of health-related quality of life designed for application in the economic evaluation of treatment and preventive programmes for children and adolescents. Previous studies have indicated that there may be systematic differences in adolescent and adult values for identical health states. An online survey including a series of best-worst scaling discrete choice experiment questions for health states defined by the CHU9D was administered to two general population samples comprising adults and adolescents, respectively. The results highlight potentially important age-related differences in the values attached to CHU9D dimensions. Adults, in general, placed less weight upon impairments in mental health (worried, sad, annoyed) and more weight upon moderate to severe levels of pain relative to adolescents. The source of values (adults or adolescents) has important implications for economic evaluation and may impact significantly upon healthcare policy.
authors.affiliation: Flinders Health Economics Group, Flinders University, Australia.
authors.forename: Julie
authors.initials: J
authors.lastname: Ratcliffe
authors.affiliation: Institute for Choice, University of South Australia, Australia.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Huynh
authors.affiliation: Health Economics and Decision Science, ScHARR, University of Sheffield, Sheffield, UK.
authors.forename: Katherine
authors.initials: K
authors.lastname: Stevens
authors.affiliation: Health Economics and Decision Science, ScHARR, University of Sheffield, Sheffield, UK.
authors.forename: John
authors.initials: J
authors.lastname: Brazier
authors.affiliation: Discipline of Paediatrics, University of Adelaide, Adelaide, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Sawyer
authors.affiliation: Centre for Research Ethics and Bioethics, Uppsala University, Uppsala, Sweden.
authors.forename: Terry
authors.initials: T
authors.lastname: Flynn
mesh_terms: D000293:Adolescent; D000067697:Adolescent Health / Q000706:statistics & numerical data*; D000328:Adult; D000367:Age Factors; D000368:Aged; D000465:Algorithms; D002648:Child; D003362:Cost-Benefit Analysis / Q000379:methods; D005260:Female; D006304:Health Status; D006306:Health Surveys; D006801:Humans; D020407:Internet; D008297:Male; D008603:Mental Health / Q000706:statistics & numerical data; D008875:Middle Aged; D011788:Quality of Life; D019057:Quality-Adjusted Life Years; D014481:United States
keywords: adolescents; adults; best-worst scaling; cost-utility analyses; health-state values