title: Spontaneous regression and recurrence of stage III Merkel cell carcinoma.
abstract: Merkel cell carcinoma (MCC) is a malignant neuroendocrine carcinoma originating in the skin. It is typically aggressive with a tendency to recur locally and metastasise. There have been several case reports about spontaneous regression of MCC over the past years, but to the best of our knowledge this is the first case of a regional lymph node metastasised MCC with complete spontaneous regression and recurrence. In addition, the primary tumour has an unusual localisation on the foot.
authors.affiliation: Department of Surgery, Maxima Medical Centre, Veldhoven, Noord-Brabant, The Netherlands.
authors.forename: Sandra Catharina Petronella
authors.initials: SC
authors.lastname: Jansen
authors.affiliation: Department of Dermatology, Máxima Medical Centre, Veldhoven, Noord-Brabant, The Netherlands.
authors.forename: Christine P M
authors.initials: CP
authors.lastname: Groeneveld-Haenen
authors.affiliation: Department of Pathology, PAMM, Eindhoven, Noord-Brabant, The Netherlands.
authors.forename: Paul J J M
authors.initials: PJ
authors.lastname: Klinkhamer
authors.affiliation: Department of Surgery, Maxima Medisch Centrum, Veldhoven, Noord-Brabant, The Netherlands.
authors.forename: Rudi M H
authors.initials: RM
authors.lastname: Roumen
mesh_terms: D015266:Carcinoma, Merkel Cell / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy; D005260:Female; D006119:Groin / Q000473:pathology*; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000532:radiotherapy; D009365:Neoplasm Regression, Spontaneous / Q000473:pathology*; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D012878:Skin Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D016896:Treatment Outcome