title: Enantioselective synthesis of macrocyclic heterobiaryl derivatives of molecular asymmetry by molybdenum-catalyzed asymmetric ring-closing metathesis.
abstract: Winding vine-shaped molecular asymmetry is induced by enantioselective ring-closing metathesis with a chiral molybdenum catalyst. The reaction proceeds under mild conditions through an E-selective ring-closing metathesis leading to macrocyclic bisazoles with enantioselectivities of up to 96% ee.
authors.affiliation: Department of Chemical Science and Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501 (Japan).
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Okayama
authors.forename: Satoru
authors.initials: S
authors.lastname: Tsuji
authors.forename: Yuka
authors.initials: Y
authors.lastname: Toyomori
authors.forename: Atsunori
authors.initials: A
authors.lastname: Mori
authors.forename: Sachie
authors.initials: S
authors.lastname: Arae
authors.forename: Wei-Yi
authors.initials: WY
authors.lastname: Wu
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Takahashi
authors.forename: Masamichi
authors.initials: M
authors.lastname: Ogasawara
keywords: asymmetric catalysis; bisimidazoles; molecular asymmetry; molybdenum catalyst; ring-closing metathesis