title: Exploiting the inflammatory response on biomaterials research and development.
abstract: Exploiting the inflammatory response on biomaterials research and development requires an in-depth understanding of the cellular and molecular mechanisms involved in the events comprising the tissue response continuum. Examples of how the biomaterial surface chemistry may modulate the foreign body reaction to biomaterials. The utilization of different surface chemistries on biomaterials may provide biological design criteria for the appropriate use and function of biomaterials when used in medical devices and prostheses.
authors.affiliation: Departments of Pathology, Macromolecular Science and Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA, jma6@case.edu.
authors.forename: James M
authors.initials: JM
authors.lastname: Anderson
mesh_terms: D001672:Biocompatible Materials / Q000009:adverse effects*; D004864:Equipment and Supplies; D005549:Foreign-Body Reaction / Q000209:etiology*; D007249:Inflammation / Q000209:etiology*; D011474:Prosthesis Design; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials