title: Birdshot retinochoroidopathy review.
abstract: Birdshot retinochoroidopathy (BSRC) is a distinct type of posterior uveitis originally described in the 1940s. Its characteristics include minimal anterior segment inflammation and diffuse posterior choroidopathy with vitritis and retinal vasculitis. The precise etiology of this disease is yet to be elucidated. However, various treatment modalities have been employed with the ultimate goal of durable remission of this vision threatening intraocular disease. The purpose of this review is not only to emphasize the importance of recognizing BSRC, but also to discuss the new discoveries, immune mediators, current and new therapies, and techniques applied to monitor and accomplish disease remission.
authors.affiliation: Massachusetts Eye Research and Surgery Institution, Cambridge, MA, USA.
authors.forename: Clovis Arcoverde
authors.initials: CA
authors.lastname: Freitas-Neto
authors.affiliation: Massachusetts Eye Research and Surgery Institution, Cambridge, MA, USA.
authors.forename: Sutasinee
authors.initials: S
authors.lastname: Boonsopon
authors.affiliation: Massachusetts Eye Research and Surgery Institution, Cambridge, MA, USA.
authors.forename: Swetha
authors.initials: S
authors.lastname: Dhanireddy
authors.affiliation: Massachusetts Eye Research and Surgery Institution, Cambridge, MA, USA.
authors.forename: Armin
authors.initials: A
authors.lastname: Maghsoudlou
authors.affiliation: Massachusetts Eye Research and Surgery Institution, Cambridge, MA, USA.
authors.forename: Sukhum
authors.initials: S
authors.lastname: Silpa-Archa
authors.affiliation: Massachusetts Eye Research and Surgery Institution, Cambridge, MA, USA.
authors.forename: C Stephen
authors.initials: CS
authors.lastname: Foster
mesh_terms: D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use; D002825:Chorioretinitis / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D015862:Choroid Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D004596:Electroretinography; D005451:Fluorescein Angiography; D015234:HLA-A Antigens / Q000276:immunology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D012074:Remission Induction; D012164:Retinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D015234:HLA-A Antigens; C035524:HLA-A29 antigen; D007166:Immunosuppressive Agents