title: Chronic Plantar Fasciitis is Mediated by Local Hemodynamics: Implications for Emerging Therapies.
abstract: Plantar fasciitis (PF) is a common, disabling condition affecting millions of patients each year. With early diagnosis and timely application of traditional nonsurgical treatments, symptoms generally resolve over time. However, despite adequate treatment, 20% of patients will experience persistent symptoms. In these patients, minimally invasive therapies that augment local hemodynamics to initiate a regenerative tissue-healing cascade have the greatest potential to resolve long-standing symptoms. We performed a narrative review based on a best evidence evaluation of manuscripts published in Medline-indexed journals to determine the mechanisms involved in soft tissue injury and healing. This evaluation also highlights emerging minimally invasive therapies that exploit these mechanisms in recalcitrant PF.
authors.affiliation: Miller Scientific Consulting, Inc., Asheville, North Carolina, United States.
authors.forename: Larry E
authors.initials: LE
authors.lastname: Miller
authors.affiliation: Department of Orthopaedic Surgery, University of Arizona, Tucson, Arizona, United States.
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Latt
keywords: Heel pain; Hemodynamics; Minimally invasive; Plantar fasciitis