title: Experimental stem cell therapies on burn wound: do source, dose, timing and method matter?
abstract: Stem cell therapy has been introduced as a new and promising modality of wound covering in recent decade. It has been used for improvement of burn wound, post burn scar and saving stasis zone of burn with good results. However, there have been some differences between the various experimental burn wound trials in stem cell source, therapeutic dose, delivery method and timing of stem cell delivery. In our study, we aimed to review stem cell biology and investigate discrepancies in animal trials of use of stem cells in burn wound account for the variation in, stem cell source, therapeutic dose, delivery method and timing of stem cell delivery.
authors.affiliation: Gulhane Military Medical Academy, Haydarpasa Training Hospital, Plastic and Reconstructive Surgery Department, Turkey. Electronic address: ozturksinan@hotmail.com.
authors.forename: Sinan
authors.initials: S
authors.lastname: Ozturk
authors.affiliation: Gulhane Military Medical Academy, Haydarpasa Training Hospital, Plastic and Reconstructive Surgery Department, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Karagoz
mesh_terms: D000818:Animals; D002056:Burns / Q000628:therapy*; D053595:Embryonic Stem Cells / Q000637:transplantation*; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods*; D033581:Stem Cell Transplantation / Q000379:methods; D013997:Time Factors; D014184:Transplantation, Homologous; D014945:Wound Healing
keywords: Burn; Regenerative medicine; Stem cell