Cutaneous pseudovasculitis, antiphospholipid syndrome and obstetric misadventure.
We present two women with severe obstetric complications from antiphospholipid (aPL) syndrome associated with a rare dermatological manifestation, cutaneous pseudovasculitis. Both of these women developed a rash on the palmar aspect of the hands during the post partum period, with histology consistent with microthrombotic disease, despite anticoagulation. Cutaneous pseudovasculitis appears to be a maternal manifestation of aPL coagulopathy, possibly reflecting the severity of the underlying pregnancy pathology.
Royal Hospital for Women, Sydney, Australia archana.selvakumar@gmail.com.
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AS
Thayaparan
Royal Hospital for Women, School of Womens'and Childrens' Health, University of New South Wales, Sydney, Australia.
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SA
Lowe
D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000276:immunology; D017152:Antibodies, Antiphospholipid / Q000276:immunology; D016736:Antiphospholipid Syndrome / Q000276:immunology* / Q000473:pathology; D005076:Exanthema / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000276:immunology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D012871:Skin Diseases / Q000276:immunology*; D014657:Vasculitis / Q000276:immunology*
D017153:Antibodies, Anticardiolipin; D017152:Antibodies, Antiphospholipid; D016682:Lupus Coagulation Inhibitor
Anticardiolipin antibodies; antiphospholipid syndrome; pregnancy; thrombosis