Anti Müllerian hormone levels before and after uterine artery embolization: A preliminary report.
OBJECTIVE
To determine the effects of uterine artery embolization on Anti-Müllerian hormone levels for women under 40 years of age.


METHODS
Non-randomized, observational study of women under 40 years of age and who received UAE. Twenty-seven women under the age of 40 who underwent UAE were included in the study. Hormone levels were measured prior to UAE, and at least six months post UAE.


RESULTS
Statistical analysis from a paired t-test showed that the AMH levels pre- and post-embolization of these women fell within the normal range. The average AMH level prior to embolization was 2.54 ± 3.99 ng/mL. The mean AMH concentration after embolization was 2.33 ± 2.70 ng/mL. The average change in AMH levels between pre-and post-embolization was -0.21 ± 1.08 ng/mL. There is no statistically significant difference between the pre- and post- UAE AMH levels (95% CI -0.64 to 0.22, p=0.32).


CONCLUSIONS
UAE does not affect ovarian reserve in women under 40 as evidenced by no significant change in AMH levels before and after embolization. Women who are of reproductive age and have fibroids can consider UAE without concern for adverse effects on their fertility.
Department of Obstetrics and Gynecology, University of California at Los Angeles, David Geffen School of Medicine , Los Angeles, CA , USA.
Bruce
B
Mclucas
William D
WD
Voorhees
Katherine Jane C
KJ
Chua
D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000628:therapy; D055357:Uterine Artery Embolization; D014594:Uterine Neoplasms / Q000628:therapy
D015415:Biomarkers; D054304:Anti-Mullerian Hormone
Anti-Müllerian hormone; embolization; fertility