[Rectal cancer with local re-recurrence successfully treated by carbon ion radiotherapy].
A 61 year-old male with rectal cancer underwent anterior resection with D2 lymph node dissection in August 2007. Carcinoembryonic antigen (CEA) level was 5.6 before the operation. Pathological findings were Rs, tub2»>tub1, type 3, pSE, ly1, v2, pN1 (1/23), H0, P0, M0 , pStage IIIA. Adjuvant chemotherapy with tegafur-uracil (UFT) 600 mg/Leucovorin (LV) 75 mg was administered for 1 year. A recurrence at a site of anastomosis developed and lower anterior resection was required in September 2010. CEA level was 5.4 before the operation. After 7 courses of capecitabine plus oxaliplatin (XELOX) treatment, the right #283 lymph node increased to 8 mm in October 2011 and the patient was diagnosed with a re-recurrence of the original tumor (CEA level, 4.6). Carbon ion radiotherapy (73.6 Gy/16 Fr/4 weeks) was performed between November 28 and December 22, 2011. Although the right #283 lymph node had shrunk by January 2012, a single node in the S3 domain of the right lung was observed and became progressively larger, indicating a lung metastasis (CEA level, 5.4). The patient received carbon ion radiotherapy (60.0 Gy/4 Fr) for the lung metastasis between July 30 and August 2, 2012. No additional recurrences have been seen through February 2014.
Dept. of Surgery, Tokyo Metropolitan Hiroo Hospital.
Masamichi
M
Okada
Masamichi
M
Yasuno
Masayo
M
Kawakami
Arisa
A
Ishihara
Fuyuki
F
Inagaki
Goshi
G
Oda
Yoshiaki
Y
Hara
Tetsuya
T
Yokosuka
Sadaaki
S
Shioiri
Toshiko
T
Kobayashi
Shigeru
S
Yamada
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D063193:Heavy Ion Radiotherapy; D006801:Humans; D008207:Lymphatic Metastasis / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D012008:Recurrence; D014057:Tomography, X-Ray Computed