Treatment of Intestinal Paralysis Using Revised Major Purgative Decoction Combined with Nasointestinal Decompression: Experience with 31 Patients.
To investigate the feasibility of using a revised major purgative decoction in combination with nasointestinal decompression for the treatment of intestinal paralysis. 31 patients with intestinal paralysis underwent gastrointestinal decompression. A fluoroscopic guided tri-lumen nasointestinal decompression tube was placed, and the patients were randomly divided into two groups: patients in the study group (n = 16) received 100 ml of a revised major purgative decoction infused through the decompression tube, three times daily; and patients in the control group (n = 15) were given neostigmine 0.5 mg by muscle injection, twice daily. The clinical presentations and imaging findings both before and after the treatment were recorded and compared. A significant increase in decompression volumes and a rapid reduction in intra-abdominal pressure (IAP) were observed in all patients undergoing nasointestinal decompression (p < 0.05). Patients in the study group achieved significantly earlier restoration of intestinal function by presenting with earlier restoration of bowel sound, earlier passage of flatus and stools (p < 0.05). The deployment of gastrointestinal decompression using a long tri-lumen nasointestinal decompression tube is effective in reducing IAP and relieve abdominal distension, whereas revised major purgative decoction can enhance the recovery of intestinal function. The joint application of these two strategies is effective and safe in the management of intestinal paralysis and is worthy of adoption in clinical settings.
Department of Medical Nutrition, Xuzhou Hospital Affiliated to Southeast University, Xuzhou, China.
Li
L
Ruihong
Department of Radiology, Xuzhou Central Hospital, Xuzhou, 221009, China. lidechun7878@sina.com.
Li
L
Dechun
Department of Radiology, Xuzhou Central Hospital, Xuzhou, 221009, China.
Shao
S
Guoqing
Department of Radiology, Xuzhou Central Hospital, Xuzhou, 221009, China.
Du
D
Hongtao
Department of Traditional Chinese Medicine, Xuzhou Central Hospital, Xuzhou, China.
Luo
L
Wei
D000005:Abdomen / Q000000981:diagnostic imaging; D000328:Adult; D000368:Aged; D002400:Cathartics / Q000627:therapeutic use; D003664:Decompression; D005260:Female; D005414:Flatulence / Q000188:drug therapy; D005471:Fluoroscopy; D006801:Humans; D007415:Intestinal Obstruction / Q000601:surgery*; D007441:Intubation, Gastrointestinal; D008297:Male; D008875:Middle Aged; D009388:Neostigmine / Q000627:therapeutic use; D011860:Radiography, Abdominal; D016896:Treatment Outcome; D014463:Ultrasonography
D002400:Cathartics; D009388:Neostigmine
Intestinal paralysis; Nasointestinal decompression; Revised major purgative decoction