Design of electrophoretic and biocompatible poly(2-oxazoline)s initiated by perfluoroalkanesulfoneimides and electrophoretic deposition with bioactive glass.
N-Methyl bis[(nonafluorobutane)sulfonyl]imide (Nf2NMe) was synthesized to serve as an initiator for polymerization of 2-oxazolines and the polymerization activity and control of molecular weight were compared with conventional methyl triflate (TfOMe). Ring-opening polymerization of the vinyl-containing 2-oxazoline, 2-(3-butenyl)-2-oxazoline, and a subsequent thiol-ene click reaction and oxidation resulted in the successful synthesis of electrophoretic poly(2-oxazoline)s containing pendent sulfone. It was possible to coat the polymeric sulfones obtained via oxone oxidation (conversion, >99%) on a stainless-steel anode selectively. Furthermore, hybridization of the poly(2-oxazoline)s with bioactive glass (Bioglass45S5) by electrophoretic deposition (EPD) was investigated, and the biocompatibility of the hybrid was also evaluated.
Department of Frontier Materials, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan.
Terunari
T
Hayashi
Department of Frontier Materials, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466-8555, Japan.
Akinori
A
Takasu
D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000494:pharmacology; D002516:Ceramics / Q000737:chemistry*; D057930:Click Chemistry; D004586:Electrophoresis; D005466:Fluorocarbons / Q000138:chemical synthesis* / Q000737:chemistry; D005898:Glass / Q000737:chemistry*; D061307:Human Umbilical Vein Endothelial Cells / Q000187:drug effects; D006801:Humans; D008698:Mesylates / Q000737:chemistry; D010080:Oxazoles / Q000737:chemistry*; D058105:Polymerization; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry
D001672:Biocompatible Materials; D005466:Fluorocarbons; D008698:Mesylates; D010080:Oxazoles; D013449:Sulfonamides; C425330:bioactive glass 45S5; C577913:poly(2-oxazoline); C078465:methyl triflate