A rare case of multilocus brain abscess due to Entamoeba histolytica infection in a child.
Brain abscess due to Entamoeba histolytica (E. histolytica) may pose a diagnostic problem or a therapeutic challenge, as evidenced by the paucity of papers reporting complete recovery after treatment. An 11-year-old girl presented with progressive drowsiness, diminished movements of the left upper limb, and swallowing problems. Cranial MRI showed multiple, contrast-dense masses with fluid content. She was started on meropenem. Surgical drainage was performed. No bacterial or fungal growth was observed in drainage samples. Entamoeba histolytica trophozoites were detected in the tissue sample. Intravenous metronidazole was started and continued for 6 weeks, at the end of which abscesses were found and to have shrunk considerably. Intravenous therapy was switched to oral metronidazole, which was continued for 2 weeks. She regained all her preexisting abilities. Multiple brain abscesses due to E. histolytica is a very rare occurrence, and histopathologic evaluation is important in diagnosis.
Department of Microbiology and Clinical Microbiology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey. E-mail. guldensonmez@hotmail.com.
Gülden S
GS
Tamer
Selim
S
Öncel
Sevil
S
Gökbulut
Emin S
ES
Arisoy
D001922:Brain Abscess / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D002648:Child; D004748:Entamoeba histolytica / Q000472:pathogenicity*; D004749:Entamoebiasis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008795:Metronidazole / Q000627:therapeutic use
D008795:Metronidazole