Platelet-to-lymphocyte ratio is a marker of poor prognosis in patients with diabetes mellitus and ST-elevation myocardial infarction.
OBJECTIVE
Platelet-to-lymphocyte ratio (PLR) has emerged as a strong marker of worse outcomes. We determined the association between PLR and clinical outcomes in patients with diabetes mellitus and ST-elevation myocardial infarction.


METHODS
Five hundred and twenty three patients were enrolled. Low PLR (group 1, n = 349) was defined as ≤ 124 and high PLR (group 2, n = 174) as >124.


RESULTS
In-hospital and 1-year mortality was higher in group 2. Receiver operating characteristic analysis revealed moderate diagnostic value in predicting in-hospital (PLR cut-off >155) and long-term (PLR cut-off >146) death. PLR remained an independent risk factor of early and late mortality.


CONCLUSIONS
PLR proved to have good prognostic value for in-hospital and late mortality. PLR cut-off value for predicting in-hospital mortality was higher to that predicting late mortality. PLR remained an independent risk factor early and late mortality.
Third Department of Cardiology, Silesian Center for Heart Disease, Medical University of Silesia, Zabrze, Poland.
Bartosz
B
Hudzik
Janusz
J
Szkodzinski
Jaroslaw
J
Gorol
Jacek
J
Niedziela
Andrzej
A
Lekston
Mariusz
M
Gasior
Lech
L
Polonski
D003920:Diabetes Mellitus / Q000097:blood* / Q000175:diagnosis* / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000175:diagnosis* / Q000503:physiopathology; D010976:Platelet Count; D011379:Prognosis
diabetes mellitus; myocardial infarction; platelet-to-lymphocyte ratio; prognosis