[Study on secondary metabolites of endophytic fungi Penicillium polonicum].
The PDB culture medium was selected to ferment the endophyte strain, and the secondary metabolites of endophytic fungi Penicillium polonicum were studied. Combined application of Sephadex LH-20, ODS and HPLC chromatographies over the ethyl acetate extract of the fermented culture led to the isolation of 6 compounds. By spectral methods, the structures were elucidated as [3, 5-dihydroxy-2-(7-hydroxy-octanoyl)]-ethylphenylacetate (1), (3, 5-dihydroxy-2- octanoyl)-ethyl phenylacetate (2), (5, 7-di- hydroxy-9-heptyl)-isobenzo pyran-3-one (3), 3-(hydroxymethyl) 4-(1E)-1- propen-1-yl-(1R, 2S, 5R, 6S)-7-oxabicyclo [4.1.0] hept-3-ene-2, 5-diol (4), (E)-2-methoxy-3-(prop-1-enyl) phenol (5) and p-hydroxylphenylethanol (6).
Jing
J
Liu
Guang-Zhi
GZ
Ding
Lei
L
Fang
Shi-Shan
SS
Yu
D001685:Biological Factors / Q000737:chemistry / Q000378:metabolism*; D060026:Endophytes / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism; D007887:Fabaceae / Q000382:microbiology*; D005285:Fermentation; D010407:Penicillium / Q000737:chemistry* / Q000302:isolation & purification / Q000378:metabolism; D064210:Secondary Metabolism
D001685:Biological Factors