Donor transmission intestinal carcinoma after kidney transplantation: case report.
Tumor transmission is a rare complication of organ transplantation. Despite several improvements in excluding donor malignant disease, there continue to be reports of unknown tumors in the donors. The risk of having a donor with an undetected malignancy ranges between 1.3% and 2%. The cases of two kidney transplant recipients who had intestinal carcinoma transmitted from the same deceased donor are described. The clinical presentation, previous data, and management options are discussed. As a result of the increase in the overall donor pool, using extended criteria donors, donors of extreme ages, donors with prolonged intensive care admission, and donors who may potentially transmit disease to their recipients, the risk of tumor transmission and also infections should be considered.
Renal Transplantation Unit, Division of Urology, University of São Paulo Medical School, São Paulo, Brazil. Electronic address: kleiton_med91@yahoo.com.br.
K G R
KG
Yamaçake
Renal Transplantation Unit, Division of Urology, University of São Paulo Medical School, São Paulo, Brazil.
I M
IM
Antonopoulos
Renal Transplantation Unit, Division of Urology, University of São Paulo Medical School, São Paulo, Brazil.
A C
AC
Piovesan
Renal Transplantation Unit, Division of Urology, University of São Paulo Medical School, São Paulo, Brazil.
H
H
Kanashiro
Renal Transplantation Unit, Division of Urology, University of São Paulo Medical School, São Paulo, Brazil.
R B
RB
Kato
Renal Transplantation Unit, Division of Urology, University of São Paulo Medical School, São Paulo, Brazil.
W C
WC
Nahas
Renal Transplantation Unit, Division of Urology, University of São Paulo Medical School, São Paulo, Brazil.
D S R
DS
David
D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000209:etiology* / Q000473:pathology; D007668:Kidney / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000601:surgery; D007680:Kidney Neoplasms / Q000556:secondary; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D014019:Tissue Donors; D055815:Young Adult