Bioinspired porous octacalcium phosphate/silk fibroin composite coating materials prepared by electrochemical deposition.
The biomimetic structure and composition of biomaterials are recognized as critical factors that determine their biological performance. A bioinspired nano-micro structured octacalcium phosphate (OCP)/silk fibroin (SF) composite coating on titanium was achieved through a mild electrochemically induced deposition method. Findings indicate that SF plays a critical role in constructing the unique biomimetic hierarchical structure of OCP/SF composite coating layers. In vitro cell culture tests demonstrate that the presence of OCP/SF composite coatings, with highly ordered and hierarchically porous structure, greatly enhance cellular responses. The coatings developed in this study have considerable potential for various hard tissue engineering and applications.
†National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, P. R. China.
Ya
Y
Yang
†National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, P. R. China.|‡Research Center of Cooperative Innovation for Functional Organic/Polymer Material Micro/Nanofabrication, Soochow University, Suzhou 215123, P. R. China.
Hui
H
Wang
†National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, P. R. China.
Feng-Yi
FY
Yan
†National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, P. R. China.
Yu
Y
Qi
†National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, P. R. China.
Yue-Kun
YK
Lai
†National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, P. R. China.
Dong-Mei
DM
Zeng
†National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, P. R. China.
Guoqiang
G
Chen
†National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, P. R. China.|‡Research Center of Cooperative Innovation for Functional Organic/Polymer Material Micro/Nanofabrication, Soochow University, Suzhou 215123, P. R. China.
Ke-Qin
KQ
Zhang
D016475:3T3 Cells; D000327:Adsorption; D000818:Animals; D040761:Biomimetic Materials / Q000138:chemical synthesis*; D002130:Calcium Phosphates / Q000737:chemistry*; D002470:Cell Survival / Q000502:physiology; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis*; D004595:Electroplating / Q000379:methods; D005349:Fibroins / Q000737:chemistry*; D008422:Materials Testing; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D016062:Porosity; D014025:Titanium / Q000737:chemistry*
D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; C022045:octacalcium phosphate; D005349:Fibroins; D014025:Titanium
OCP; cell culture; composite coating; nano-micro structure; silk fibroin