BUB1-bling over with possibilities.
In a new report, Nyati et al. identified a previously undetected participant mediating both canonical signaling, i.e., TGF-β receptor kinase mediated, and non-canonical signaling, budding uninhibited by benzimidazole 1 (BUB1).
Department of Radiation Oncology New York University, School of Medicine, New York, NY. Electronic address: mhbarcellos-hoff@nyumc.org.
Mary Helen
MH
Barcellos-Hoff
D000818:Animals; D006801:Humans; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D018125:Receptors, Transforming Growth Factor beta / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D051896:Smad Proteins, Receptor-Regulated / Q000378:metabolism*; D016212:Transforming Growth Factor beta / Q000502:physiology*
D018125:Receptors, Transforming Growth Factor beta; D051896:Smad Proteins, Receptor-Regulated; D016212:Transforming Growth Factor beta; D017346:Protein Serine-Threonine Kinases