[A case of cardiac tamponade due to pericarditis carcinomatosa of breast cancer successfully treated via pericardiocentesis and systemic chemo-endocrine therapy].
We report a case of lung and bone metastases of right advanced breast cancer in a 33-year-old woman. Her breast cancer (T4bN1M1, StageIV)was resected in December 2003 (mastectomy [BT] plus axillary lymph node dissection [AX]) after local arterial infusion therapy and subsequent systemic chemo-endocrine therapy was initiated and continued. In June 2007, a computed tomography (CT) scan revealed cardiac tamponade due to pericarditis carcinomatosa. Pericardiocentesis was performed, and the bloody effusion was drained immediately. Subsequently, the sysytemic chemo-endocrine therapy was modified. In 2009, multiple cerebellar metastases were discovered and treated via whole brain irradiation. In 2010, multiple liver metastases appeared, and they were treated by intravenous (IV) administration of nab-paclitaxel. In 2011, superior vena cava syndrome appeared gradually, and it was treated via venous metallic stenting. In 2012, epidural spinal cord compression appeared gradually, and it was treated via irradiation. In November 2012, the patient died because of lymphangitis carcinomatosa; her prognosis was good, as it was approximately 5 years after the pericardiocentesis.
Dept. of Surgery, Ohkubo Hospital.
Eigo
E
Satoh
Masakazu
M
Ebuchi
Keiichiro
K
Suzuki
Disuke
D
Uehira
Shingo
S
Ono
Kouji
K
Yonekura
Ayano
A
Murakata
Hideo
H
Tanami
Shouji
S
Maruyama
Norihide
N
Sugano
Michio
M
Maruyama
Jun
J
Matsumoto
Takaaki
T
Sakoma
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*; D002305:Cardiac Tamponade / Q000209:etiology / Q000628:therapy*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D020519:Pericardiocentesis; D010493:Pericarditis / Q000209:etiology* / Q000628:therapy