[Interaction of C60 fullerene-polyvinylpyrrolidone complex and brain Aβ(1-42)-peptide in vitro].
Using a spectrophotometric method changes occurring in solution containing brain Aβ(1-42)-peptide, fullerene C60, and polyvinylpyrrolidone were analyzed. Using the Bent-French method relative binding constants of fullerene C60 with Aβ(1-42)-peptide and polyvinylpyrrolidone with Aβ(1-42)- peptide were determined. These data suggest that Aβ(1-42)-peptide interacting with the C60 fullerene-polyvinylpyrrolidone complex partially displaces polyvinylpyrrolidone and generates a new three molecular compound.
A G
AG
Bobylev
Iu V
IuV
Shatalin
I M
IM
Vikhliantsev
L G
LG
Bobyleva
S V
SV
Gudkov
Z A
ZA
Podlubnaia
D016229:Amyloid beta-Peptides / Q000737:chemistry*; D037741:Fullerenes / Q000737:chemistry*; D006801:Humans; D010446:Peptide Fragments / Q000737:chemistry*; D011205:Povidone / Q000737:chemistry*
D016229:Amyloid beta-Peptides; D037741:Fullerenes; D010446:Peptide Fragments; C075222:amyloid beta-protein (1-42); D011205:Povidone; C069837:fullerene C60