The International Nucleome Consortium.
The eukaryotic genome adopts in the cell nucleus a 3-dimensional configuration that varies with cell types, developmental stages and environmental condition as well as between normal and pathological states. Understanding genome function will therefore require the elucidation of the structure-function relationship of the cell nucleus as a complex, dynamic biological system, referred to as the nucleome. This exciting and timely task calls for a multi-faceted, interdisciplinary and multi-national effort. We propose the establishment of an International Nucleome Consortium to coordinate this effort worldwide.
a Institute for Radiation Biology and Medicine ; Hiroshima University ; Minamiku , Hiroshima , Japan.
Satoshi
S
Tashiro
Christian
C
Lanctôt
D000818:Animals; D005075:Biological Evolution; D002467:Cell Nucleus / Q000378:metabolism*; D060833:Cellular Microenvironment; D002874:Chromosome Mapping; D004194:Disease; D016678:Genome; D006801:Humans; D038622:Internationality; D008954:Models, Biological; D009707:Nucleosomes / Q000378:metabolism; D010641:Phenotype
D009707:Nucleosomes
4D genome organization; international consortium; nucleome; research themes; scientific collaboration