Human embryo cryopreservation-methods, timing, and other considerations for optimizing an embryo cryopreservation program.
The contribution of embryo cryopreservation to the birth rate per in vitro fertilization cycle has escalated from a rare subsidy to a vital tool that is called upon to augment the cycle outcome. Embryology laboratories must identify the embryo stage, quality criteria and methodology that will optimize their ability to preserve each embryo's reproductive potential. This chapter reviews the principles of cryopreservation, outcomes based on embryo stage and cryopreservation method and benchmarks that may be employed by the laboratory to measure the performance of their embryo cryopreservation program.
Department of Obstetrics and Gynecology, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa.
Amy E T
AE
Sparks
D019985:Benchmarking / Q000592:standards; D001755:Blastocyst / Q000187:drug effects / Q000502:physiology*; D015925:Cryopreservation / Q000592:standards*; D003451:Cryoprotective Agents / Q000627:therapeutic use; D005260:Female; D005298:Fertility / Q000187:drug effects; D005307:Fertilization in Vitro / Q000592:standards*; D006801:Humans; D007246:Infertility / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D017410:Practice Guidelines as Topic / Q000592:standards*; D011247:Pregnancy; D018873:Pregnancy Rate; D019984:Quality Indicators, Health Care / Q000592:standards; D013997:Time Factors; D016896:Treatment Outcome; D058989:Vitrification
D003451:Cryoprotective Agents