Self-consistent magnetic properties of magnetite tracers optimized for magnetic particle imaging measured by ac susceptometry, magnetorelaxometry and magnetic particle spectroscopy.
Sensitivity and spatial resolution in Magnetic Particle Imaging are affected by magnetic properties of the nanoparticle tracers used during imaging. Here, we have carried out a comprehensive magnetic characterization of single-core iron oxide nanoparticles that were designed for MPI. We used ac susceptometry, fluxgate magnetorelaxometry, and magnetic particle spectroscopy to evaluate the tracer's magnetic core size, hydrodynamic size, and magnetic anisotropy. Our results present a self-consistent set of magnetic and structural parameters for the tracers that is consistent with direct measurements of size using transmission electron microscopy and dynamic light scattering and that can be used to better understand their MPI performance.
Institute of Electrical Measurement and Fundamental Electrical Engineering, TU, Braunschweig, Hans-Sommer-Str. 66, D-38106 Braunschweig, Germany.
Frank
F
Ludwig
Institute of Electrical Measurement and Fundamental Electrical Engineering, TU, Braunschweig, Hans-Sommer-Str. 66, D-38106 Braunschweig, Germany.
Hilke
H
Remmer
Institute of Electrical Measurement and Fundamental Electrical Engineering, TU, Braunschweig, Hans-Sommer-Str. 66, D-38106 Braunschweig, Germany.
Christian
C
Kuhlmann
Institute of Electrical Measurement and Fundamental Electrical Engineering, TU, Braunschweig, Hans-Sommer-Str. 66, D-38106 Braunschweig, Germany.
Thilo
T
Wawrzik
Department of Materials Science & Engineering, Box 352120, University of Washington, Seattle, WA98195, USA.
Hamed
H
Arami
Department of Materials Science & Engineering, Box 352120, University of Washington, Seattle, WA98195, USA.
R Mathew
RM
Ferguson
Department of Materials Science & Engineering, Box 352120, University of Washington, Seattle, WA98195, USA.
Kannan M
KM
Krishnan