[A case of malignant phyllodes tumor after surgery for breast cancer].
A 63-year-old woman underwent breast-conserving resection and axillary lymph node dissection for bilateral breast cancer in December 2008. Histopathological diagnosis for the right breast cancer was t=1.3 cm, n=1/29, estrogen receptor (ER) (+), progesterone receptor (PgR) (+), human epidermal growth factor receptor 2(HER2) (-), and that for the left breast cancer was t=1.8 cm, n=9/28, ER (+), PgR (+), and HER2 (-). She was administered adjuvant chemotherapy (4 courses of fluorouracil, epirubicin, and cyclophosphamide [FEC 100] and 4 courses of docetaxel[DTX], 75 mg/m²), letrozole, and bilateral radiation therapy for the remaining breast tissue. She noticed a mass in the left breast in December 2013. Fine-needle aspiration cytology and core-needle biopsy indicated a malignant phyllodes tumor or stromal sarcoma. Positron emission tomography-computed tomography (PET-CT) revealed the accumulation of fluorodeoxyglucose (FDG) only in the mass. The tumor enlarged rapidly to more than 5 cm during the pre-operative period. In January 2014, the patient underwent left mastectomy. The histopathological diagnosis was malignant phyllodes tumor in the left breast, with a tumor diameter of 7 cm, and negative margins. Presently, 6 months after the operation, the patient is alive without recurrence.
Dept. of Surgery, Kansai Rosai Hospital.
Tadayoshi
T
Hashimoto
Masatsugu
M
Okishiro
Tomo
T
Ishida
Yasufumi
Y
Sato
Yoshihiro
Y
Morimoto
Hiroki
H
Kusama
Katsunori
K
Matsushita
Kei
K
Kimura
Yoshiteru
Y
Katsura
Kanae
K
Nitta
Yoshinori
Y
Kagawa
Atsushi
A
Takeno
Hideki
H
Sakisaka
Shin
S
Nakahira
Hirokazu
H
Taniguchi
Chiyomi
C
Egawa
Yutaka
Y
Takeda
Takeshi
T
Kato
Shigeyuki
S
Tamura
Yuichi
Y
Takatsuka
Kazuko
K
Oku
Takayoshi
T
Goto
Teruaki
T
Nagano
Shinichi
S
Nakatsuka
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D008875:Middle Aged; D064847:Multimodal Imaging; D003557:Phyllodes Tumor / Q000188:drug therapy* / Q000601:surgery; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed