Miconazole and oral anticoagulants: bleeding.
Increases in the INR and cases of bleeding have been reported during concomitant use of miconazole oral gel or mucoadhesive buccal tablets and a vitamin K antagonist (fluindione or warfarin).
D000278:Administration, Buccal; D000925:Anticoagulants / Q000008:administration & dosage* / Q000009:adverse effects*; D000935:Antifungal Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D001777:Blood Coagulation / Q000187:drug effects*; D004347:Drug Interactions; D006470:Hemorrhage / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D019934:International Normalized Ratio; D008825:Miconazole / Q000008:administration & dosage* / Q000009:adverse effects*; D061214:Patient Safety; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index
D000925:Anticoagulants; D000935:Antifungal Agents; D008825:Miconazole