[Diagnostic value of hemomyelogram for acute appendicitis].
OBJECTIVE
To analyze the relationship between hemomyelogram and sererity of acute appendicitis and identify the best routine blood test feature for perforation.


METHODS
721 patients were included in this study, all of whom underwent appendectomy for the clinical diagnosis of appendicitis during the years of 2010-2013. The initial preoperative hemomyelogram was evaluated at different stages of appendicitis. The area under the ROC curve was used to assess the clinical feature with greater diagnostic accuracy of perforation. Total lymphocyte counts of 1.83 was used in the prediction of perforative appendicitis. A group of 467 patients was used for validation to confirm the diagnostic value of the cut-off value.


RESULTS
The percentage of lymphocytes had the closest association with the evolutionary phase of acute appendicitis. Total lymphocyte counts < or=1.83 indicated perforation, with high sensitivity and low specificity.


CONCLUSIONS
The percentage of lymphocytes and total lymphocyte counts are helpful as a diagnostic paramete for different stages of acute appendicitis.
Department of Immunology, Medical College, Hunan Normal University, Changsha 410013, China.E-mail: peggy.z.8287@163.com.
PeiPei
P
Zhang
Wei
W
Yan
Zhi
Z
Zeng
Ran
R
Zhang
Kaimin
K
Xiang
Yuxiong
Y
DU
Na
N
Chen
Yiping
Y
Li
D000208:Acute Disease; D001062:Appendectomy; D001064:Appendicitis / Q000175:diagnosis*; D006801:Humans; D018655:Lymphocyte Count; D012372:ROC Curve; D012680:Sensitivity and Specificity