Validation of the Spanish version of the Pediatric Asthma Caregiver Quality of Life Questionnaire (PACQLQ) in a population of Hispanic children.
OBJECTIVE
The Paediatric Asthma Caregiver's Quality of Life Questionnaire (PACQLQ) is intended to measure the impact of children's asthma on their parents/caregiver's QoL. However, there are no formal validation studies of the Spanish version of PACQLQ.


METHODS
In a prospective cohort validation study, asthmatic children aged between 7 and 17 years and their parents, attended both a baseline and a follow-up visit 2-6 weeks later. In these two visits, we gathered the necessary data for assessing the criterion validity, construct validity, test-retest reliability, sensitivity to change, internal consistency and usability of the PACQLQ.


RESULTS
At baseline, PACQLQ scores were significantly different between patients with controlled, partly controlled and uncontrolled asthma (median [IQR] 78.0 [61.0-85.0], 71.0 [37.0-76.0] and 48.0 [40.7-55.0], respectively, p < 0.001), and also between patients for whom this visit resulted in a step-up versus no change or a step-down in therapy (50.0 [40.0-60.0] versus 78.0 [61.0-85.0]; p < 0.001). PACQLQ scores at baseline were significantly lower than those obtained in the follow-up visit in patients with change for the better in the global rating of change questionnaire (median [IQR] 50.0 [42.5-56.0] versus 80.0 [78.5-85.0]; p < 0.001). The intraclass correlation coefficient of the measurements was 0.839 (95%CI: 0.735-0.902). The Cronbach α was 0.914 for the questionnaire as a whole.


CONCLUSIONS
The Spanish version of the PACQLQ has adequate construct validity, adequate sensitivity to change, good internal consistency, excellent test-retest reliability and good usability when employed in children aged between 7 and 17 years with physician-diagnosed asthma.
a Department of Pediatrics , School of Medicine, Universidad Nacional de Colombia , Bogota , Colombia .
Carlos E
CE
Rodríguez-Martínez
Monica P
MP
Sossa-Briceño
Gustavo
G
Nino
D000293:Adolescent; D001249:Asthma / Q000523:psychology*; D002648:Child; D003105:Colombia / Q000453:epidemiology; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D010290:Parents / Q000523:psychology*; D011446:Prospective Studies; D011788:Quality of Life; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
Asthma; health-related quality of life; pediatrics; reliability; validation studies; validity