Molecular epidemiology study of swine influenza virus revealing a reassorted virus H1N1 in swine farms in Cuba.
In this report, we describe the emergence of reassorted H1N1 swine influenza virus, originated from a reassortment event between the H1N1 pandemic influenza virus (H1N1p/2009) and endemic swine influenza virus in Cuban swine population. In November 2010, a clinical respiratory outbreak was reported on a pig fattening farm in Cuba. Phylogenetic analysis showed that all the genes of one of the isolate obtained, with the exception of neuraminidase, belonged to the H1N1p/2009 cluster. This finding suggests that H1N1pdm has been established in swine and has become a reservoir of reassortment that may produce new viruses with both animal and public health risks.
Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba. Electronic address: lesterjosue@gmail.com.
Lester J
LJ
Pérez
Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba.
Carmen Laura
CL
Perera
Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba.
Liani
L
Coronado
Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba.
Liliam
L
Rios
Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba.
Armando
A
Vega
Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba.
Maria T
MT
Frías
Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Campus de la Universitat Autònoma de Barcelona, Bellaterra, Cerdanyola del Vallès, Spain.
Llilianne
L
Ganges
Centre de Recerca en Sanitat Animal (CReSA), UAB-IRTA, Campus de la Universitat Autònoma de Barcelona, Bellaterra, Cerdanyola del Vallès, Spain.
José Ignacio
JI
Núñez
Centro Nacional de Sanidad Agropecuaria (CENSA), La Habana, Cuba; Hospital Italiano de Buenos Aires, Juan D. Perón 4190, C1181ACH Buenos Aires, Argentina.
Heidy
H
Díaz de Arce
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003462:Cuba / Q000453:epidemiology; D016679:Genome, Viral; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000235:genetics / Q000378:metabolism; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D009976:Orthomyxoviridae Infections / Q000453:epidemiology* / Q000235:genetics / Q000821:virology; D010802:Phylogeny; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000235:genetics / Q000821:virology
C543345:H1N1 virus hemagglutinin; D019267:Hemagglutinin Glycoproteins, Influenza Virus
Phylogenetic analysis; Reassortant; Swine influenza virus