25 years of African trypanosome research: From description to molecular dissection and new drug discovery.
The Molecular Parasitology conference was first held at the Marine Biological laboratory, Woods Hole, USA 25 years ago. Since that first meeting, the conference has evolved and expanded but has remained the showcase for the latest research developments in molecular parasitology. In this perspective, I reflect on the scientific discoveries focussed on African trypanosomes (Trypanosoma brucei spp.) that have occurred since the inaugural MPM meeting and discuss the current and future status of research on these parasites.
Centre for Immunity, Infection and Evolution, Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3JT, UK. Electronic address: keith.matthews@ed.ac.uk.
Keith R
KR
Matthews
D000818:Animals; D000981:Antiprotozoal Agents / Q000266:history / Q000494:pharmacology; D055808:Drug Discovery / Q000266:history* / Q000639:trends; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D014346:Trypanosoma brucei brucei / Q000187:drug effects / Q000235:genetics / Q000502:physiology*; D014353:Trypanosomiasis, African / Q000188:drug therapy / Q000266:history / Q000469:parasitology*
D000981:Antiprotozoal Agents
Molecular parasitology; Trypanosoma brucei; Trypanosome