Asymmetric hydroamination catalyzed by a new chiral zirconium system: reaction scope and mechanism.
A new class of chiral zirconium complexes supported by chiral tridentate [O(-)NO(-)]-type of ligands derived from amino acids were synthesized and structurally characterized. They catalyzed asymmetric hydroamination/cyclization of primary aminoalkenes to give five- and six-membered N-heterocyclic amines with up to 94% ee.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, P. R. China. tangy@sioc.ac.cn.
Xiaoguang
X
Zhou
Bing
B
Wei
Xiu-Li
XL
Sun
Yong
Y
Tang
Zuowei
Z
Xie