Unilateral Vocal Cord Motion Impairment After 1 Dose of Vincristine: Case Report and Literature Review.
Vocal cord paralysis after administration of the chemotherapeutic agent vincristine is a rare occurrence. Most occurrences are bilateral. Of the 24 cases referenced in this article, 19 are children. In all the reported cases, symptoms have occurred after multiple doses of vincristine have been administered. The authors report a case of a 39-year-old woman with unilateral vocal cord motion impairment occurring 3 days after the administration of the first dose of vincristine. This is the first case of vocal cord motion impairment reported after the administration of only 1 dose of this drug.
Department of Surgery, Head and Neck Section, Fox Chase Cancer Center, Temple University Health System, Philadelphia, PA.
Hillary
H
Aaron
Roya
R
Azadarmaki
Miriam N
MN
Lango
D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D001859:Bone Neoplasms / Q000188:drug therapy*; D005260:Female; D006801:Humans; D012512:Sarcoma, Ewing / Q000188:drug therapy*; D014750:Vincristine / Q000009:adverse effects*; D014826:Vocal Cord Paralysis / Q000139:chemically induced*
D000972:Antineoplastic Agents, Phytogenic; D014750:Vincristine