[Alkaloids from roots and stems of Litsea cubeba].
A phytochemical investigation on the roots and stems of Litsea cubeba led to the isolation of seven isoquinolone alkaloids. By spectroscopic analysis and comparison of their 1H and 13C-NMR data with those in literatures, these alkaloids were identified as (+)-norboldine (1), (+)-boldine (2), (+)-reticuline (3), (+)-laurotetanine (4), (+)-isoboldine (5), (+)-N-methyl-laurotetanine (6), and berberine (7), respectively. Among them, 7 was isolated from the genus for the first time. The evaluation of these compounds showed weak anti-inflammatory activity against NO production in RAW 267.4 and BV-2 cells.
Shui-Ying
SY
Zhang
Qiang
Q
Guo
Yuan
Y
Cao
Yuan
Y
Zhang
Xiao-Li
XL
Gao
Peng-Fei
PF
Tu
Xing-Yun
XY
Chai
D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D032862:Litsea / Q000737:chemistry*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
D004365:Drugs, Chinese Herbal