Four additional cases of Diphyllobothrium nihonkaiense infection confirmed by analysis of COX1 gene in Korea.
Most of the diphyllobothriid tapeworms isolated from human samples in the Republic of Korea (= Korea) have been identified as Diphyllobothrium nihonkaiense by genetic analysis. This paper reports confirmation of D. nihonkaiense infections in 4 additional human samples obtained between 1995 and 2014, which were analyzed at the Department of Parasitology, Hallym University College of Medicine, Korea. Analysis of the mitochondrial cytochrome c oxidase 1 (cox1) gene revealed a 98.5-99.5% similarity with a reference D. nihonkaiense sequence in GenBank. The present report adds 4 cases of D. nihonkaiense infections to the literature, indicating that the dominant diphyllobothriid tapeworm species in Korea is D. nihonkaiense but not D. latum.
Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon 200-704, Korea.
Sang Hyun
SH
Park
Department of Parasitology and Medical Research Institute, Chungbuk National University College of Medicine, Cheongju 361-763, Korea.
Hyeong Kyu
HK
Jeon
Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon 200-704, Korea.
Jin Bong
JB
Kim
D000818:Animals; D001483:Base Sequence; D016000:Cluster Analysis; D004169:Diphyllobothriasis / Q000175:diagnosis* / Q000469:parasitology*; D004170:Diphyllobothrium / Q000145:classification* / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D003576:Electron Transport Complex IV / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D056910:Republic of Korea; D017422:Sequence Analysis, DNA; D017385:Sequence Homology
D003576:Electron Transport Complex IV
Diphyllobothrium latum; Diphyllobothrium nihonkaiense; cox1 gene