Inhibition of farnesoid X receptor signaling shows beneficial effects in human obesity.
Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20814, USA. Electronic address: gonzalef@mail.nih.gov.
Frank J
FJ
Gonzalez
Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Peking University, Beijing 100191, PR China.
Changtao
C
Jiang
Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA.
William H
WH
Bisson
Department of Veterinary and Biomedical Sciences, Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, PA 16802, USA.
Andrew D
AD
Patterson
D001647:Bile Acids and Salts / Q000378:metabolism*; D006801:Humans; D050356:Lipid Metabolism / Q000187:drug effects*; D009767:Obesity, Morbid / Q000188:drug therapy* / Q000378:metabolism*; D018160:Receptors, Cytoplasmic and Nuclear / Q000037:antagonists & inhibitors*; D014580:Ursodeoxycholic Acid / Q000494:pharmacology*
D001647:Bile Acids and Salts; D018160:Receptors, Cytoplasmic and Nuclear; D014580:Ursodeoxycholic Acid