Impact of the 13-valent pneumococcal conjugate vaccine on nasopharyngeal carriage of Streptococcus pneumoniae among children attending group daycare in southeastern France.
Regular surveys of pneumococcal nasopharyngeal carriage have been conducted among children attending daycare centers in Southeastern France from 1999 to 2012. We compared carriage rate, susceptibility patterns and serotype distribution in 2012, following implementation of the 13-valent pneumococcal conjugate vaccine, with findings from 5 previous surveys. Carriage rate was stable, antibiotic susceptibility improved and only serotype 19A persisted among vaccine-types.
From the *Public Health Department, and †Clinical Research Department, Nice University Hospital; ‡Fondation Lenval; and §Laboratoire de bactériologie, Nice University Hospital, Nice, France.
Brigitte
B
Dunais
Pascale
P
Bruno
Pia
P
Touboul
Nicolas
N
Degand
Charlotte
C
Sakarovitch
Eric
E
Fontas
Hervé
H
Haas
Fernand
F
Girard-Pipau
Raymond
R
Ruimy
Christian
C
Pradier
D002353:Carrier State / Q000517:prevention & control*; D002656:Child Day Care Centers; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005602:France / Q000453:epidemiology; D000069443:Heptavalent Pneumococcal Conjugate Vaccine / Q000008:administration & dosage / Q000276:immunology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D058885:Multilocus Sequence Typing; D009305:Nasopharynx / Q000382:microbiology*; D011008:Pneumococcal Infections / Q000453:epidemiology / Q000517:prevention & control*; D022242:Pneumococcal Vaccines / Q000276:immunology*; D011159:Population Surveillance; D065288:Serogroup; D013296:Streptococcus pneumoniae / Q000145:classification / Q000235:genetics / Q000276:immunology*; D018074:Vaccines, Conjugate / Q000276:immunology*
C538862:13-valent pneumococcal vaccine; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D022242:Pneumococcal Vaccines; D018074:Vaccines, Conjugate