Solitary epibulbar neurofibroma in older adult patients.
OBJECTIVE
To report a solitary epibulbar neurofibroma in 2 elderly patients without systemic neurofibromatosis.


METHODS
Case reports and literature review.


RESULTS
A 67-year-old man presented with a 2-month history of left epibulbar mass. On slit-lamp examination, an 8- × 8-mm amelanotic, translucent, gelatinous, circumscribed lesion was present deep to the nasal bulbar conjunctiva. A 60-year-old otherwise healthy man presented with a 6-week history of a subconjunctival growth causing pain and photophobia in his right eye. On slit-lamp examination, an 8- × 8-mm amelanotic, translucent, gelatinous, circumscribed subconjunctival lesion, causing a delle was present near the nasal limbus. In each case, excisional biopsy was performed and histopathologic study revealed the diagnosis of neurofibroma. In both cases, after 12 months of follow-up, there was no evidence of recurrence or systemic disease.


CONCLUSIONS
Solitary epibulbar neurofibroma in older adult patients without systemic neurofibromatosis is rare but should be considered in the differential diagnosis of epibulbar tumors.
*Department of Ophthalmology and Vision Sciences, WK Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, MI; and †Department of Pathology, University of Michigan Medical School, Ann Arbor, MI.
Thais Shiota
TS
Tanaka
Victor M
VM
Elner
Hakan
H
Demirci
D000368:Aged; D003230:Conjunctival Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D009455:Neurofibroma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013508:Ophthalmologic Surgical Procedures