Animal models of regression/progression of kidney disease.
Current medical therapies may delay chronic kidney disease progression. However, increasing experimental evidence indicates remission or even regression can be achieved. In order to study mechanisms progression vs. regression by different interventions, appropriate animal models and research design must be implemented. We review key information of selected models, including etiology, pathogenesis, procedure, time course and assessment of potential regression.
Dept. of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States ; Dept. of Pathology, Yonsei University College of Medicine, Seoul, Korea.
Beom Jin
BJ
Lim
Dept. of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.
Hai-Chun
HC
Yang
Dept. of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.
Agnes B
AB
Fogo