The Sordid Affair Between Human Herpesvirus and HIV.
Both human immunodeficiency virus (HIV) and human herpesvirus (HHV) infections persist lifelong, and almost all individuals infected with HIV are also infected with ≥1 HHV. These coinfections are not independent processes or benign. In this review, we discuss how HHVs, and cytomegalovirus in particular, interact with concurrent HIV infection, and we describe the next steps necessary to understand and address these connections.
University of California San Diego, La Jolla.
Sara
S
Gianella
University of California San Diego, La Jolla.
Marta
M
Massanella
University of California San Diego, La Jolla.
Joel O
JO
Wertheim
University of California San Diego, La Jolla Veterans Affairs San Diego Healthcare System, California.
Davey M
DM
Smith
D060085:Coinfection / Q000150:complications*; D006678:HIV / Q000502:physiology*; D015658:HIV Infections / Q000150:complications*; D006564:Herpesviridae / Q000145:classification* / Q000502:physiology*; D006566:Herpesviridae Infections / Q000150:complications*; D006801:Humans
HIV; Human herpesvirus; cytomegalovirus; epidemiology transmission; inflammation; pathogenesis