Effects of whole-body vibration on acute bone turnover marker responses to resistance exercise in young men.
OBJECTIVE
We investigated acute bone turnover marker (BTM) responses to high-intensity resistance exercise with and without whole-body vibration (WBV) in young men (n=10).


METHODS
In this randomized crossover study, subjects performed 2 protocols separated by 2-week wash out periods: 1) resistance exercise only (RE) (3 sets 10 repetitions 80% 1RM for 9 exercises); and 2) WBV + RE (side-alternating vibration platform 5 intermittent, 1-minute bouts 20 Hz, 3.38 mm peak-to-peak displacement followed by RE). Fasting morning blood draws were taken before RE or WBV (PRE), immediately post RE (IP), and 30 minutes post RE (30P). WBV + RE also had a blood draw after the WBV exposure (POST WBV). Blood samples were analyzed for lactate, hematocrit, bone-specific alkaline phosphatase (Bone ALP, U/L), C-terminal telopeptide of type I collagen (CTX-I, ng/mL) and tartrate-resistant acid phosphatase 5b (TRAP5b, U/L).


RESULTS
Lactate, hematocrit, and Bone ALP significantly increased (p<0.05) IP for both protocols. Bone resorption markers did not change during RE only. CTX-I significantly decreased POST WBV. TRAP5b increased POST WBV, then significantly decreased at 30P.


CONCLUSIONS
Generally, BTM changes to RE only were not significant when adjusted for hemoconcentration. The WBV stimulus altered bone resorption marker but not bone formation marker responses.
Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, USA.
D A
DA
Bemben
P
P
Sharma-Ghimire
Z
Z
Chen
E
E
Kim
D
D
Kim
M G
MG
Bemben
D000135:Acid Phosphatase / Q000097:blood; D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D001862:Bone Resorption; D001842:Bone and Bones / Q000502:physiology; D024042:Collagen Type I / Q000097:blood; D018592:Cross-Over Studies; D015444:Exercise / Q000502:physiology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007527:Isoenzymes / Q000097:blood; D008297:Male; D010012:Osteogenesis / Q000502:physiology*; D010455:Peptides / Q000097:blood; D055070:Resistance Training; D000071681:Tartrate-Resistant Acid Phosphatase; D014732:Vibration; D055815:Young Adult
D024042:Collagen Type I; D007527:Isoenzymes; D010455:Peptides; C052929:collagen type I trimeric cross-linked peptide; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D000071681:Tartrate-Resistant Acid Phosphatase