Relative and absolute structure of phomolide C.
Phomolide C (1) was isolated from a fungus Diaporthe sp. being found at Shirakami mountainous area. Although only the planar structure of 1 has been known, our detailed NMR spectroscopic analysis and ECD studies revealed its both relative and absolute configuration.
a The United Graduate School of Agricultural Science , Iwate University , Morioka , Japan.
Atsushi
A
Ito
Hyato
H
Maeda
Akio
A
Tonouchi
Masaru
M
Hashimoto
D001203:Ascomycota / Q000737:chemistry*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D045744:Cell Line, Tumor / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D002942:Circular Dichroism; D006801:Humans; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
D019086:Bridged Bicyclo Compounds, Heterocyclic; D007783:Lactones; C000607297:phomolide C
NOE; dibenzoate rule; electric circular dichroism (ECD) spectrum; phomolide C; stereochemistry