An exploratory path model of the relationships between positive and negative adaptation to cancer on quality of life among non-Hodgkin lymphoma survivors.
Adaptation is an ongoing, cognitive process with continuous appraisal of the cancer experience by the survivor. This exploratory study tested a path model examining the personal (demographic, disease, and psychosocial) characteristics associated with quality of life (QOL) and whether or not adaptation to living with cancer may mediate these effects. This study employed path analysis to estimate adaptation to cancer. A cross-sectional sample of NHL survivors (N = 750) was used to test the model. Eligible participants were ≥ 18 years, at least 2 years post-diagnosis, and living with or without active disease. Sixty-eight percent of the variance was accounted for in QOL. The strongest effect (-0.596) was direct by negative adaptation, approximately 3 times that of positive adaptation (0.193). The strongest demographic total effects on QOL were age and social support; <65 years of age had better QOL and better adaptation compared to those ≥ 65. Of the disease characteristics, comorbidity score had the strongest direct effect on QOL; each additional comorbidity was associated with a 0.309 standard deviation decline on QOL. There were no fully mediated effects through positive adaptation alone. Our exploratory findings support the coexistence of positive and negative adaptations perception as mediators of personal characteristics of the cancer experience. Negative adaptation can affect QOL in a positive way. Cancer survivorship is simultaneously shaped by both positive and negative adaptation with future research and implications for practice aimed at improving QOL.
a School of Nursing, University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
Ashley Leak
AL
Bryant
Sophia K
SK
Smith
Catherine
C
Zimmer
Jamie
J
Crandell
Coretta M
CM
Jenerette
Donald E
DE
Bailey
Sheryl
S
Zimmerman
Deborah K
DK
Mayer
D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000523:psychology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D008960:Models, Psychological; D011788:Quality of Life / Q000523:psychology*; D017741:Survivors / Q000523:psychology* / Q000706:statistics & numerical data
adaptation; cancer survivors; non-Hodgkin lymphoma; quality of life; structural equation modeling