Effect of computer radiation on weight and oxidant-antioxidant status of mice.
OBJECTIVE
To explore the effects of computer radiation on weight and oxidant-antioxidant status of mice, and further to confirm that whether vitamin C has protective effects on computer radiation.


METHODS
Sixty Male adult ICR mice were randomly divided into six groups. each group give different treatment as follows: group A was control, group B given vitamin C intake, group C given 8 h/day computer radiation exposure, group D given vitamin C intake and 8 h/day computer radiation group E given 16 h/day computer radiation exposure, group F given vitamin C intake plus exposure to 16 h/day computer radiation. After seven weeks, mice was executed to collect the blood samples, for detecting total antioxidant capacity (T-AOC) and alkaline phosphatases (ALP)content in serum or liver tissue were determined by ELISA.


RESULTS
No difference was found for the change of weight among six groups at different week. In the group C, D and F, the liver tissue T-AOC level were higher than the group A. In the group B, C and E, the serum ALP level were lower than the group A (P<0.05).


CONCLUSIONS
The study indicate that computer radiation may have an adverse effect on T-AOC and ALP level of mice, and vitamin C have protective effect against computer radiation.
School of public Health, Wannan Medical College, Wuhu,Anhui 241002, China.. 1481047190@qq.com.
Xuexian
X
Pei
School of public Health, Wannan Medical College, Wuhu,Anhui 241002, China.. 545166270@qq.com.
Qijun
Q
Gu
School of public Health, Wannan Medical College, Wuhu,Anhui 241002, China.. 597888447@qq.com.
Dongdong
D
Ye
School of public Health, Wannan Medical College, Wuhu,Anhui 241002, China.. 1983renxiaohua@163.com.
Yang
Y
Wang
School of public Health, Wannan Medical College, Wuhu,Anhui 241002, China.. lianpinghe@126.com.
Xu
X
Zou
School of public Health, Wannan Medical College, Wuhu,Anhui 241002, China.. 1983helianping@163.com.
Lianping
L
He
School of public Health, Wannan Medical College, Wuhu,Anhui 241002, China.. 94017416@qq.com.
Yuelong
Y
Jin
School of public Health, Wannan Medical College, Wuhu,Anhui 241002, China.. yingshuiyao@163.com.
Yingshui
Y
Yao
D000469:Alkaline Phosphatase / Q000032:analysis; D000818:Animals; D000975:Antioxidants / Q000032:analysis* / Q000627:therapeutic use; D001205:Ascorbic Acid / Q000627:therapeutic use; D001835:Body Weight / Q000528:radiation effects*; D003201:Computers; D060733:Electromagnetic Radiation; D008099:Liver / Q000737:chemistry / Q000528:radiation effects; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D016877:Oxidants; D018384:Oxidative Stress / Q000528:radiation effects*; D011837:Radiation-Protective Agents / Q000627:therapeutic use; D011897:Random Allocation
D000975:Antioxidants; D016877:Oxidants; D011837:Radiation-Protective Agents; D000469:Alkaline Phosphatase; D001205:Ascorbic Acid