Salivary diagnostics using a portable point-of-service platform: a review.
Clinical diagnostics can be improved by faster and more accessible disease detection. Our laboratory has developed a point-of-service (POS) device capable of rapid, sensitive, automated, and multiplexed biomarker detection that uses human saliva instead of other biofluids. Here, we review the technology that led to the development of this POS device. This POS technology can advance clinical diagnostics by saving time because of faster diagnosis, saving money because of a shorter hospital stay, and ultimately improving clinical care.
Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA 02111.
Prarthana
P
Khanna
Department of Chemistry, Tufts University, Medford, Massachusetts. Electronic address: david.walt@tufts.edu.
David R
DR
Walt
D015415:Biomarkers / Q000032:analysis*; D003933:Diagnosis; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods; D000067716:Point-of-Care Testing; D012463:Saliva / Q000737:chemistry*
D015415:Biomarkers
biomarker; detection; device; diagnostic; disease; saliva