Hematogenous dissemination of Candida dubliniensis causing spondylodiscitis and spinal abscess in a HIV-1 and HCV-coinfected patient.
We report a case of spondylodiscitis and spinal abscess following haematogenous dissemination of the emerging yeast Candida dubliniensis in a human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV)-coinfected patient. Although C. dubliniensis is considered less virulent compared to its closest known relative Candida albicans, reports of severe fungal infections are increasing. This case indicates that the pathogenicity of C. dubliniensis may be higher than previously believed. Therefore fungal infections caused by this dimorph fungus should be kept in mind in immunocompromised patients with spondylodiscitis and spinal abscess.
Department of Internal Medicine I, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Helmut J F
HJ
Salzer
Department of Internal Medicine I, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Thierry
T
Rolling
Institute of Medical Microbiology, Virology and Hygiene, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Eva-Maria
EM
Klupp
Department of Internal Medicine I, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
Stefan
S
Schmiedel
Candida dubliniensis; Hepatitis C virus; Human immunodeficiency virus-1; Spinal abscess; Spondylodiscitis