[A case of renal salt-wasting syndrome during chemotherapy for advanced gastric cancer].
A 66-year-old woman was admitted to our hospital with heartburn and liver dysfunction. She was diagnosed with advanced gastric cancer. After the initiation of chemotherapy with trastuzumab, capecitabine, and cisplatin, she developed hyponatremia and renal failure with renal salt-wasting syndrome (RSWS). She recovered from these conditions after infusion of hypertonic saline. A diagnosis of RSWS should be considered in patients with hyponatremia who receive cisplatin-based chemotherapy.
Dept. of Gastroenterology, Mitoyo General Hospital.
Hisae
H
Yasuhara
Atsushi
A
Imagawa
Nao
N
Koike
Eijiro
E
Ueta
Akihiro
A
Matsumi
Hiroyuki
H
Terasawa
Hiroyuki
H
Sakae
Keiko
K
Takeuchi
Manabu
M
Fujihara
Hitomi
H
Endo
Hideki
H
Jinno
Akio
A
Moriya
Hidenori
H
Hata
Morihito
M
Nakatsu
Masaharu
M
Ando
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced*; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary; D012964:Sodium / Q000097:blood*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology
D012964:Sodium; D002945:Cisplatin