A therapeutic-only versus prophylactic platelet transfusion strategy for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation.
This is the protocol for a review and there is no abstract. The objectives are as follows: To determine whether a therapeutic-only platelet transfusion policy (platelet transfusions given when patient bleeds) is as effective and safe as a prophylactic platelet transfusion policy (platelet transfusions given to prevent bleeding usually when the platelet count falls below a given trigger level) in patients with haematological disorders undergoing myelosuppressive chemotherapy or stem cell transplantation.
Haematology/Transfusion Medicine, NHS Blood and Transplant, Oxford, UK.
Lise J
LJ
Estcourt
Clinical Haematology, Royal Children' s Hospital Melbourne, Melbourne, Australia.
Gemma L
GL
Crighton
Department of Clinical Haematology, Monash University, Melbourne, Australia.
Erica M
EM
Wood
Haematology/Transfusion Medicine, NHS Blood and Transplant, Oxford, UK.
Simon
S
Stanworth
Centre for Statistics in Medicine, University of Oxford, Oxford, UK.
Marialena
M
Trivella
Systematic Review Initiative, NHS Blood and Transplant, Oxford, UK.
Carolyn
C
Doree
Medicine (hematology) and Pathology Centre for Transfusion Research, The Ottawa Health Research Institute and the University of Ottawa, Ottawa, Canada.
Alan
A
Tinmouth
NHS Blood and Transplant, John Radcliffe Hospital, Oxford, UK.
Michael F
MF
Murphy