A case of endocrine cell carcinoma combined with squamous cell carcinoma of the esophagus resected by endoscopic submucosal dissection.
A 55-year-old man with esophageal carcinoma received endoscopic submucosal dissection (ESD) in en-bloc resection. Histopathological examination revealed an admixture of squamous cell carcinoma (SCC) and endocrine cell carcinoma (ECC) with invasion of the deep submucosa. Immunohistochemically, CD 56 and chromogranin A were positive for ECC. Small-cell, medium-cell, and large-cell type ECC were partly surrounded with SCC and partly formed the duct, presenting various patterns. After ESD, he received chemotherapy including CPT-11 plus Cisplatin. He is alive and in good condition today, 55 months after ESD, with no evidence of recurrence.
Department of Gastroenterology and Rheumatology School of Medicine, Fukushima Medical University; Department of Endoscopy, Fukushima Medical University Hospital, Japan.
Ko
K
Watanabe
Takuto
T
Hikichi
Masaki
M
Sato
Jun
J
Nakamura
Tadayuki
T
Takagi
Rei
R
Suzuki
Mitsuru
M
Sugimoto
Yuichi
Y
Waragai
Hitomi
H
Kikuchi
Naoki
N
Konno
Hiroshi
H
Watanabe
Katsutoshi
K
Obara
Hiromasa
H
Ohira
D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D055098:Endocrine Cells / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery