(18)F-FDOPA accumulation in traumatic rib fractures: a potential pitfall.
F-FDOPA (6-[F]fluoro-L-DOPA) is used for the detection and staging of neuroendocrine tumors by visualizing the uptake of amine precursors in these tumors with high sensitivity and specificity. However, as this tracer is only available in a limited number of centers worldwide and the minority of the nuclear medicine specialists and referring clinicians is familiar with the distribution pattern of F-FDOPA, some physiological uptake patterns and pitfalls remain to be fully elucidated. Here, we present 2 cases of markedly increased uptake in the ribs after traumatic injury.
From the Department of Nuclear Medicine and Molecular Imaging, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Gilles N
GN
Stormezand
Andor W J M
AW
Glaudemans
Riemer H J A
RH
Slart
D003951:Diagnostic Errors; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012253:Rib Fractures / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; C043437:fluorodopa F 18; D004295:Dihydroxyphenylalanine