Bromination of olefins with HBr and DMSO.
A simple and inexpensive methodology is reported for the conversion of alkenes to 1,2-dibromo alkanes via oxidative bromination using HBr paired with dimethyl sulfoxide, which serves as the oxidant as well as cosolvent. The substrate scope includes 21 olefins brominated in good to excellent yields. Three of six styrene derivatives yielded bromohydrins under the reaction conditions.
Department of Chemistry, University of Idaho, Moscow, Idaho 83844, United States.
Megha
M
Karki
Department of Chemistry, University of Idaho, Moscow, Idaho 83844, United States.
Jakob
J
Magolan