Is antigenic sin always "original?" Re-examining the evidence regarding circulation of a human H1 influenza virus immediately prior to the 1918 Spanish flu.
Département de Démographie, Université de Montréal, Montreal, Quebec, Canada.
Alain
A
Gagnon
Département de Démographie, Université de Montréal, Montreal, Quebec, Canada.
J Enrique
JE
Acosta
Department of Microbiology and Immunology and Microbiome and Disease Tolerance Centre, McGill University, Montreal, Quebec, Canada.
Joaquin
J
Madrenas
Department of Biochemistry and Biomedical Sciences, Institute for Infectious Diseases Research, McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada.
Matthew S
MS
Miller
D000328:Adult; D005260:Female; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics* / Q000276:immunology*; D064149:Influenza Pandemic, 1918-1919 / Q000266:history; D008297:Male; D010802:Phylogeny; D012425:Russia (Pre-1917)