Dengue fever: natural management.
Dengue fever is caused by the mosquito-borne dengue virus (DENV) serotypes 1-4, and is the most common arboviral infection of humans in subtropical and tropical regions of the world. Dengue virus infections can present with a spacious range of clinical signs, from a mild feverish illness to a life-threatening shock syndrome. Till now, there is no approved vaccine or drug against this virus. Therefore, there is an urgent need of development of alternative solutions for dengue. Several plant species have been reported with anti-dengue activity. Many herbal/natural drugs, most of which are commonly used as nutritional components, have been used as antiviral, larvicidal, mosquitocidal and mosquito repellents that may be used against dengue. The objective of this review article was to provide current approaches for the treatment and management/prevention of dengue fever by targeting viral proteins involved in replication cycle of the virus and different developmental stages of mosquito.
Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan.
Muhammad Imran
MI
Qadir
College of Pharmacy, GC University, Faisalabad, Pakistan.
Khizar
K
Abbas
College of Pharmacy, GC University, Faisalabad, Pakistan.
Madeha
M
Tahir
College of Pharmacy, GC University, Faisalabad, Pakistan.
Muhammad
M
Irfan
College of Pharmacy, GC University, Faisalabad, Pakistan.
Syeda Fiza
SF
Raza Bukhari
College of Pharmacy, GC University, Faisalabad, Pakistan.
Bilal
B
Ahmed
Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.
Muhammad
M
Hanif
College of Pharmacy, GC University, Faisalabad, Pakistan.
Akhtar
A
Rasul
Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan.
Muhammad
M
Ali
D003715:Dengue / Q000188:drug therapy*; D003716:Dengue Virus / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007302:Insect Repellents / Q000494:pharmacology; D009032:Mosquito Control; D008517:Phytotherapy; D014779:Virus Replication / Q000187:drug effects
D007302:Insect Repellents