ALK Positive Anaplastic Large Cell Lymphoma Presenting as Extensive Bone Involvement.
Anaplastic lymphoma kinase (ALK) positive Anaplastic large cell lymphoma (ALCL) represents approximately 2% of all Non-Hodgkin's lymphomas that commonly involves nodal as well as a wide variety of extra nodal sites, as skin, soft tissue, bones and lungs, although primary or secondary involvement of bone is rare. Herein, we report a case of 14-year-old female child presented as extensive bony involvement with a clinical diagnosis of bone tumour/ small round cell tumour, which was proved to be ALK positive ALCL on histopathological examination.
Attending Consultant, Department of Pathology and Laboratory Medicine, Medanta-The Medicity , Sector -38, Gurgaon, Haryana, India .
Smeeta
S
Gajendra
Senior Consultant, Department of Pathology and Laboratory Medicine, Medanta-The Medicity , Sector -38, Gurgaon, Haryana, India .
Ritesh
R
Sachdev
Associate Consultant, Department of Pathology and Laboratory Medicine, Medanta-The Medicity , Sector -38, Gurgaon, Haryana, India .
Lipika
L
Lipi
Attending Consultant, Department of Pathology and Laboratory Medicine, Medanta-The Medicity , Sector -38, Gurgaon, Haryana, India .
Shalini
S
Goel
Consultant, Department of Pediatric Medical Oncology, Medanta-The Medicity , Sector -38, Gurgaon, Haryana, India .
Ruchira
R
Misra
Anaplastic large cell lymphoma; Anaplastic lymphoma kinase; CD30; Multifocal osseous involvement