[A case of neoadjuvant chemotherapy for locally advanced rectal cancer, which had a invasion into the vagina followed by curative resection].
A-64-years-old woman with locally advanced rectal cancer, which had invaded the vagina, was referred to our hospital. She was administered neoadjuvant chemotherapy to reduce the tumor size. After 4 courses of chemotherapy consisting of folinic acid, fluorouracil, and oxaliplatin (mFOLFOX6), an enhanced computed tomography (CT) scan and magnetic resonance imaging (MRI) indicated marked tumor shrinkage. We performed a laparoscopically assisted low anterior resection, which included total mesorectal resection, resection of the vaginal posterior wall, and right lateral lymph node resection. The chemotherapy prevented us from having to create a permanent colostomy. The efficacy of the neoadjuvant chemotherapy was Grade 1b. We experienced a case of neoadjuvant chemotherapy followed by curative resection.
Dept. of Surgery, Kansai Rosai Hospital.
Kei
K
Kimura
Yoshinori
Y
Kagawa
Takeshi
T
Kato
Tomo
T
Ishida
Yoshihiro
Y
Morimoto
Katsunori
K
Matusita
Hiroki
H
Kusama
Tadayoshi
T
Hashimoto
Yoshiteru
Y
Katura
Kanae
K
Nitta
Atushi
A
Takeno
Shin
S
Nakahira
Masatsugu
M
Okishiro
Hideki
H
Sakisaka
Hirokazu
H
Taniguchi
Chiyomi
C
Egawa
Yutaka
Y
Takeda
Shigeyuki
S
Tamura
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D010535:Laparoscopy; D002955:Leucovorin / Q000008:administration & dosage; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D014621:Vagina / Q000473:pathology* / Q000601:surgery
D009944:Organoplatinum Compounds; D002955:Leucovorin; D005472:Fluorouracil