Immune-modulating activities of polysaccharides extracted from brown algae Hizikia fusiforme.
The immuno-modulating activities of seaweed (Hizikia fusiforme) extracts on murine macrophage and splenocyte were studied in vitro. Polysaccharide (HFP) exhibited the potential macrophage stimulating effects than water extract (HFW) such as NO production and enhanced pro-inflammatory cytokines on the Raw 264.7 cells and splenocytes. From the mono-sugar composition, HFP-associated fucose based on HFP of H. fusiforme acts as immune modulator.
a HK Bio, Business Incubator , Daegu Haany University , Gyeongsan , Republic Korea.
Sang Chul
SC
Jeong
Yong Tae
YT
Jeong
Sang Myung
SM
Lee
Jin Hee
JH
Kim
D000818:Animals; D007155:Immunologic Factors / Q000008:administration & dosage*; D008264:Macrophages / Q000187:drug effects*; D051379:Mice; D000459:Phaeophyceae / Q000737:chemistry; D010936:Plant Extracts / Q000008:administration & dosage* / Q000737:chemistry / Q000276:immunology; D011134:Polysaccharides / Q000008:administration & dosage* / Q000737:chemistry / Q000276:immunology
D007155:Immunologic Factors; D010936:Plant Extracts; D011134:Polysaccharides
Hizikia fusiforme; cytokines; macrophage; polysaccharide; splenocyte