Alternaria-Associated Fungus Ball of Orbit Nose and Paranasal Sinuses: Case Report of a Rare Clinical Entity.
Alternaria-associated fungus ball of maxillar, ethmoidal paranasal sinuses, nasal cavity and orbit with bone erosion is extremely rare. Till recently, only two cases of this infection in immune competitive patients have been reported. We are herein describing the case of immune-competent woman who suffered of nasal congestion for 10 years. Patient was treated for tumor-like lesion in right maxillar sinus, where propagation in right nose cavity, right ethmoidal cells and right orbita was present. The organism that was seen in surgical removal of fungal debris by histological study, in using mycological testing, was proven as Alternaria alternata. Combination of surgical intervention and treatment with itraconazole eradicated fungal infection, and the disease was not relapsed in follow-up period of 2 years.
Department of Maxillofacial Surgery, Faculty of Medicine, University of Nis, Blvd Zorana Djindjica 81, 18000, Nis, Serbia, pesic.z@gmail.com.
Zoran
Z
Pesic
Suzana
S
Otasevic
Dragan
D
Mihailovic
Sladjana
S
Petrovic
Valentina
V
Arsic-Arsenijevic
Dragan
D
Stojanov
Milica
M
Petrovic
D000528:Alternaria / Q000302:isolation & purification*; D000935:Antifungal Agents / Q000627:therapeutic use; D003646:Debridement; D005260:Female; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008828:Microbiological Techniques; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D009666:Nose / Q000382:microbiology / Q000473:pathology; D009668:Nose Diseases / Q000150:complications / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D009915:Orbit / Q000382:microbiology / Q000473:pathology; D009916:Orbital Diseases / Q000150:complications / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D010256:Paranasal Sinuses / Q000382:microbiology / Q000473:pathology; D012852:Sinusitis / Q000150:complications / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D016896:Treatment Outcome
D000935:Antifungal Agents; D017964:Itraconazole