Evolutionary genetics of insect innate immunity.
Patterns of evolution in immune defense genes help to understand the evolutionary dynamics between hosts and pathogens. Multiple insect genomes have been sequenced, with many of them having annotated immune genes, which paves the way for a comparative genomic analysis of insect immunity. In this review, I summarize the current state of comparative and evolutionary genomics of insect innate immune defense. The focus is on the conserved and divergent components of immunity with an emphasis on gene family evolution and evolution at the sequence level; both population genetics and molecular evolution frameworks are considered.
Lumi
L
Viljakainen
D000818:Animals; D019143:Evolution, Molecular; D017344:Genes, Insect; D054884:Host-Pathogen Interactions; D007113:Immunity, Innate / Q000235:genetics*; D007313:Insecta / Q000235:genetics* / Q000276:immunology*
AMP; Imd; Toll; gene family evolution; positive selection