Confetti clarifies controversy: neural crest stem cells are multipotent.
Neural crest precursors generate diverse cell lineages during development, which have been proposed to arise either from multipotent precursor cells or pools of heterogeneous, restricted progenitors. Now in Cell Stem Cell, Baggiolini et al. (2015) perform rigorous in vivo lineage tracing to show that individual neural crest precursors are multipotent.
Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: mbronner@caltech.edu.
Marianne
M
Bronner
D000818:Animals; D000943:Antigens, Differentiation / Q000378:metabolism*; D019070:Cell Lineage / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology*; D039902:Multipotent Stem Cells / Q000378:metabolism*; D009432:Neural Crest / Q000196:embryology* / Q000378:metabolism*
D000943:Antigens, Differentiation