Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report.
Cemento-ossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibroma transforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all osteosarcomas. A 45-year-old female patient was diagnosed with cemento-ossifying fibroma, treated with mass excision several times over a period of two years and eight months, and followed up. After biopsy gathered because of signs of recurrence, she was diagnosed with low-grade osteosarcoma. The patient underwent wide excision, segmental mandibulectomy, and reconstruction with fibula free flap. The aim of this report is to raise awareness of the possibility that cemento-ossifying fibroma can transform into osteosarcoma and of the consequent necessity for careful diagnosis and treatment planning.
Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Korea.
Yong Bin
YB
Lee
Department of Dentistry, Catholic Kwandong University International St. Mary's Hospital, Incheon, Korea.
Nam-Kyoo
NK
Kim
Department of Oral and Maxillofacial Surgery, Gangnam Severance Hospital, Yonsei University College of Dentistry, Seoul, Korea.
Jae-Young
JY
Kim
Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Korea. ; Oral Cancer Research Institute, Yonsei University College of Dentistry, Seoul, Korea.
Hyung Jun
HJ
Kim
Cemento ossifying fibroma; Low-grade osteosarcoma