[Choroid plexus tumour treatment at Hospital Infantil Niño Jesús in Madrid: Our experience over the last three decades].
OBJECTIVE
To review childhood patients with choroid plexus tumors (CPT) who underwent surgery at Hospital Infantil Niño Jesús of Madrid since January 1981 to September 2014.


METHODS
Registered charts were analyzed based on the epidemiology, tumor grade, clinical profile, location, dissemination characteristics, therapy, prognosis and complications.


RESULTS
Seventeen childhood patients were recorded with CPT. Cases were distributed so that 9 cases were choroid plexus-papilloma (CPP) (52.9%), 2 cases atypical CPP (11.7%) and 6 cases choroid plexus-carcinoma (CPC) (35.2%). Age at diagnosis was less than 2 years in 14 of the 17 patients (82.3%) and the incidence was higher in males (82.3% of the cases). Gross total resection was performed in 16 patients (94.1%). Adjuvant treatment was used in 6 patients (all this cases with CPC) (35.2%). Two of the 17 patients died (11.7%), showing an incidence density of 0.01 deaths/year.


CONCLUSIONS
Our case series is consistent with previous published in scientific literature regarding epidemiology, tumor grade, clinical presentation, radiological features and therapeutic approach. Gross total resection is considered the therapeutic gold standard for choroid plexus tumors. Chemotherapy and radiotherapy should be used as adjuvant treatment in CPC and recurrent or remaining atypical CPP.
Servicio de Neurocirugía, Hospital Universitario Central de Asturias (HUCA), Oviedo, Asturias, España.
Isabel
I
Cuervo-Arango
Servicio de Neurocirugía, Hospital Universitario Central de Asturias (HUCA), Oviedo, Asturias, España. Electronic address: pedroreimunde@gmail.com.
Pedro
P
Reimunde
Servicio de Neurocirugía, Hospital Universitario Central de Asturias (HUCA), Oviedo, Asturias, España.
Julio César
JC
Gutiérrez
Servicio de Neurocirugía, Hospital Universitario Niño Jesús, Madrid, España.
Ana
A
Aransay
Servicio de Neurocirugía, Hospital Universitario Niño Jesús, Madrid, España.
Belén
B
Rivero
Servicio de Neurocirugía, Hospital Universitario Niño Jesús, Madrid, España.
Carlos
C
Pérez
Servicio de Neurocirugía, Hospital Universitario Niño Jesús, Madrid, España.
Marcelo
M
Budke
Servicio de Neurocirugía, Hospital Universitario Niño Jesús, Madrid, España.
Francisco
F
Villarejo
D016545:Choroid Plexus Neoplasms / Q000175:diagnosis / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D020288:Papilloma, Choroid Plexus / Q000175:diagnosis / Q000628:therapy*; D011379:Prognosis; D013030:Spain
Brain tumour; Carcinoma de plexos coroideos; Choroid plexus-carcinoma; Choroid plexus-papilloma; Neuro-Oncology; Neurocirugía; Neurooncología; Neuropaediatrics; Neuropediatría; Neurosurgery; Papiloma de plexos coroideos; Tumor cerebral