Hispanic Americans living in the United States and their risk for obesity, diabetes and kidney disease: Genetic and environmental considerations.
The Hispanic American, the largest minority population in the United States, is at increased risk for obesity, diabetes and end-stage renal disease. Here we review genetic and environmental factors that might account for their increased risk for these conditions. Whereas many environmental and genetic factors have important roles in driving the increased risk for obesity and kidney disease in this population, a case is made that excessive intake of sugary beverages is a contributory cause. Studies focusing on decreasing intake of sugary beverages among the Hispanic American could potentially reduce renal and cardiovascular complications in this population.
Department of Pharmaceutics, School of Pharmacy, University of Washington , Seattle, WA , USA.
Joseph M
JM
Yracheta
Javier
J
Alfonso
Miguel A
MA
Lanaspa
Carlos
C
Roncal-Jimenez
Sarah B
SB
Johnson
Laura G
LG
Sánchez-Lozada
Richard J
RJ
Johnson
D003920:Diabetes Mellitus / Q000208:ethnology*; D059647:Gene-Environment Interaction; D006630:Hispanic or Latino / Q000208:ethnology / Q000706:statistics & numerical data*; D006801:Humans; D007674:Kidney Diseases / Q000208:ethnology*; D009765:Obesity / Q000208:ethnology*; D051436:Renal Insufficiency, Chronic / Q000208:ethnology; D012307:Risk Factors; D012959:Socioeconomic Factors; D014481:United States / Q000453:epidemiology
Hispanic American; chronic kidney disease; diabetes; fructose; health disparities; metabolic syndrome; obesity; sugar