Multi-organ involvement of Sweet's syndrome: a case report and literature review.
The hallmark of Sweet's syndrome (SS) is the infiltration of mature neutrophils in the upper dermis. We herein report a case of SS with multi-organ involvement. A 32-year-old man presented with fever, anemia and dyspnea. He was given antibiotics, without any improvements. Later, a number of erythematous lesions appeared, accompanied by deteriorating respiratory and cardiovascular functions. A diagnosis of SS was confirmed on a skin biopsy, and the patient was given corticosteroids, the dose of which was reduced after one month. The organ function subsequently deteriorated, and he ultimately died of multi-organ failure. Early recognition of SS with multi-organ involvement is important in patients with SS.
Department of Respiratory Medicine, Second Clinical Hospital, Jilin University; Department of Occupational Disease Prevention, Jilin Provincial Occupational Disease Prevention and Treatment, China.
Bo
B
Li
Zhongsen
Z
Ma
Xuesong
X
Xu
Jinzhi
J
Yin
Xiuli
X
Wang
Jin
J
Ren
Songyan
S
Wang
Junling
J
Yang
Tiangang
T
Ma
Qinghua
Q
Zhang
Jinyan
J
Yu
Bingdi
B
Yan
D061605:Administration, Intravenous; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D000328:Adult; D000740:Anemia / Q000209:etiology; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001706:Biopsy; D057210:Delayed Diagnosis; D004334:Drug Administration Schedule; D004417:Dyspnea / Q000209:etiology; D017809:Fatal Outcome; D005334:Fever / Q000209:etiology; D006801:Humans; D008297:Male; D009102:Multiple Organ Failure / Q000209:etiology* / Q000473:pathology*; D009504:Neutrophils / Q000473:pathology; D012867:Skin / Q000473:pathology*; D016463:Sweet Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents