[Metabolic encephalopathy secondary to vitamin D intoxication].
The association between vitamin D deficiency and increased risk of, among others, cardiovascular and autoimmune diseases has lead in the last years to an enhanced interest in the usage of supplements to achieve the normalization of plasmatic values at 25(OH) D. Apparently this search for normalization is resulting in an higher incidence on vitamin D intoxication. We present the case of an 81 years old woman with metabolic encephalopathy and renal failure secondary to iatrogenic vitamin D intoxication. Calcium and vitamin D oral supplements were prescribed after an osteoporotic vertebral fracture. The patient improved clinically as well as analytically after receiving treatment with diuretics and hydration. We emphasize the importance of discarding hypercalcemia as a cause of metabolic encephalopathy; moreover we highly recommend keeping vitamin D intoxication in mind as an uncommon although always possible etiology of reversible hypercalcemia and renal failure.
Unidad de Gestión Clínica de Endocrinología y Nutrición.. contentine@gmail.com.
Aura
A
Herrera Martínez
Unidad de Gestión Clínica de Neurología.. contentine@gmail.com.
Montserrat
M
Viñals Torràs
Unidad de Gestión Clínica de Endocrinología y Nutrición.. contentine@gmail.com.
Ma Concepción
MC
Muñoz Jiménez
Unidad de Gestión Clínica de Medicina Interna. Hospital Universitario Reina Sofía. Córdoba. España.. contentine@gmail.com.
Antonio Pablo
AP
Arenas de Larriva
Unidad de Gestión Clínica de Endocrinología y Nutrición.. contentine@gmail.com.
Ma José
MJ
Molina Puerta
Unidad de Gestión Clínica de Endocrinología y Nutrición.. contentine@gmail.com.
Gregorio
G
Manzano García
Unidad de Gestión Clínica de Endocrinología y Nutrición.. contentine@gmail.com.
Ma Ángeles
MÁ
Gálvez Moreno
Unidad de Gestión Clínica de Endocrinología y Nutrición.. contentine@gmail.com.
Alfonso
A
Calañas-Continente
D000058:Accidental Falls; D000284:Administration, Oral; D000369:Aged, 80 and over; D001928:Brain Diseases, Metabolic / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D002112:Calcifediol / Q000009:adverse effects*; D002118:Calcium / Q000009:adverse effects / Q000627:therapeutic use; D003072:Cognition Disorders / Q000209:etiology* / Q000628:therapy; D006259:Craniocerebral Trauma / Q000150:complications; D003681:Dehydration / Q000150:complications; D015161:Dementia, Multi-Infarct / Q000175:diagnosis; D019587:Dietary Supplements / Q000009:adverse effects*; D005260:Female; D005440:Fluid Therapy; D005598:Fractures, Spontaneous / Q000209:etiology; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced* / Q000150:complications; D054559:Hyperphosphatemia / Q000139:chemically induced; D007049:Iatrogenic Disease; D015663:Osteoporosis, Postmenopausal / Q000150:complications / Q000188:drug therapy; D012074:Remission Induction; D014807:Vitamin D / Q000031:analogs & derivatives / Q000097:blood
D014807:Vitamin D; D005665:Furosemide; C104450:25-hydroxyvitamin D; D002112:Calcifediol; D002118:Calcium