[A case of long-term survival of advanced gastric cancer with schnitzler metastasis effectively treated with combination chemotherapy].
A 66-year-old woman was diagnosed with unresectable advanced gastric cancer with Schnitzler metastasis in January 2012. She was treated with combination chemotherapy comprising S-1 and docetaxel (DTX). However, in January 2013, after 13 courses of treatment, a computed tomography (CT) indicated peritoneal dissemination growth. The chemotherapy regimen was changed to a combination of S-1 and irinotecan (CPT-11), but after a single course of treatment the patient complained of stomachaches and vomiting. The patient developed ileus from the stenosis of the rectum, and a transanal ileus tube was used to decompress the bowel tract. Due to the patient's poor general condition, a metallic stent was inserted, and she could resume eating. Thereafter, we changed the chemotherapy regimen to weekly paclitaxel (PTX). However, 1 year and 4 months after starting treatment she died of regrowth of the peritoneal disseminating lesions. We recommend a combination of chemotherapy and metallic stent placement to improve quality of life and long-term survival.
Dept. of Surgery, Suita Municipal Hospital.
Yuma
Y
Wada
Kazuyuki
K
Okada
Chikara
C
Ebisui
Tetsu
T
Yanagisawa
Shu
S
Okamura
Nariaki
N
Fukuchi
Kouhei
K
Murata
Hideoki
H
Yokouchi
Masakatsu
M
Kinuta
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D045823:Ileus / Q000209:etiology / Q000628:therapy; D008875:Middle Aged; D009362:Neoplasm Metastasis; D015607:Stents; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology