Motility disorders, functional gastrointestinal disorders, inflammatory bowel disease and cardiac rhythm disturbances - is there a link? Review of literature.
Gastrointestinal disorders are frequently accompanied by symptoms exceeding gastrointestinal tract. This is at least partially connected with the involvement of autonomic nervous system in pathophysiology of diseases such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) or spectrum of motility disorders. In light of the above, involvement of cardiovascular system in natural history of gastrointestinal disorders seems to be of interest. On the other hand, available data regarding the prevalence of cardiac rhythm disturbances in IBD, IBS and motility disorders is limited. What is more, pharmacotherapy of the mentioned diseases includes drugs with possible arrhythmogenic potential. In this review we present current experiences and observations concerning gastrointestinal disorders and cardiac rhythm disturbances.
Michał
M
Żorniak
Marek
M
Waluga
Department of Gastroenterology and Hepatology, Medical University of Silesia, Katowice, Poland. dr.zorniak@gmail.com.
Marek
M
Hartleb
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000175:diagnosis* / Q000453:epidemiology; D002316:Cardiotonic Agents / Q000009:adverse effects*; D005767:Gastrointestinal Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000453:epidemiology; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000139:chemically induced / Q000175:diagnosis* / Q000453:epidemiology
D002316:Cardiotonic Agents