Chemoselective hydrogenation of carbonyl compounds and acceptorless dehydrogenative coupling of alcohols.
OsHCl(CO)[κ(3)-PyCH2NHC2H4NHPtBu2] is the first efficient catalyst for chemoselective reduction of challenging unsaturated esters to enols and for acceptorless coupling of amines with MeOH and EtOH affording formamides and acetamides. The NMR, ESI-MS, and DFT data indicate a mechanism proceeding in the metal coordination sphere and producing no free organic intermediates.
†Department of Chemistry and Biochemistry, Wilfrid Laurier University, Waterloo, Ontario N2L 3C5, Canada.
Denis
D
Spasyuk
‡Serveis Centrals d'Instrumentació Científica, Universitat Jaume I, 12071 Castellón, Spain.
Cristian
C
Vicent
†Department of Chemistry and Biochemistry, Wilfrid Laurier University, Waterloo, Ontario N2L 3C5, Canada.
Dmitry G
DG
Gusev