Voriconazole-Resistant Penicillium oxalicum: An Emerging Pathogen in Immunocompromised Hosts.
Penicillium species are rarely reported agents of infections in immunocompromised patients. We report 3 cases of invasive mycosis caused by voriconazole-resistant Penicillium oxalicum in patients with acute myeloid leukemia, diabetes mellitus, and chronic obstructive pulmonary disease, while on voriconazole therapy. Penicillium oxalicum has not been previously recognized as a cause of invasive mycoses.
Vallabhbhai Patel Chest Institute , University of Delhi , Delhi , India.
Anuradha
A
Chowdhary
Vallabhbhai Patel Chest Institute , University of Delhi , Delhi , India.
Shallu
S
Kathuria
Rajan Babu Institute of Pulmonary Medicine and Tuberculosis , Delhi , India.
Kshitij
K
Agarwal
Rajiv Gandhi Cancer Institute & Research Centre , Delhi , India.
Neelam
N
Sachdeva
Vallabhbhai Patel Chest Institute , University of Delhi , Delhi , India.
Pradeep K
PK
Singh
Rajiv Gandhi Cancer Institute & Research Centre , Delhi , India.
Sandeep
S
Jain
Canisius-Wilhelmina Hospital , Nijmegen , The Netherlands ; Radboud University Medical Centre , Nijmegen , The Netherlands.
Jacques F
JF
Meis
India; Penicillium oxalicum; immunocompromised; invasive; posaconazole; voriconazole resistance