The survival mechanisms of thermophiles at high temperatures: an angle of omics.
Thermophiles are referred to as microorganisms with optimal growth temperatures of >60 °C. Over the past few years, a number of studies have been conducted regarding thermophiles, especially using the omics strategies. This review provides a systematic view of the survival physiology of thermophiles from an "omics" perspective, which suggests that the adaptive ability of thermophiles is based on a cooperative mode with multi-dimensional regulations integrating genomics, transcriptomics, and proteomics.
Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China; and BGI-Shenzhen, Shenzhen, China wangqh@genomics.org.cn.
Quanhui
Q
Wang
Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China; and.
Zhen
Z
Cen
Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China; and.
Jingjing
J
Zhao
D000222:Adaptation, Physiological; D001419:Bacteria / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism*; D019143:Evolution, Molecular; D015964:Gene Expression Regulation, Bacterial; D023281:Genomics / Q000379:methods; D006358:Hot Temperature; D055432:Metabolomics / Q000379:methods; D050296:Microbial Viability; D055550:Protein Stability; D040901:Proteomics / Q000379:methods
D001426:Bacterial Proteins