Gaseous modulators in the control of the hypothalamic neurohypophyseal system.
Nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S) are gaseous molecules produced by the brain. Within the hypothalamus, gaseous molecules have been highlighted as autocrine and paracrine factors regulating endocrine function. Therefore, in the present review, we briefly discuss the main findings linking NO, CO, and H2S to the control of body fluid homeostasis at the hypothalamic level, with particular emphasis on the regulation of neurohypophyseal system output.
Department of Physiology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil; and.
Silvia Graciela
SG
Ruginsk
Department of Physiology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil; and.
Andre de Souza
AS
Mecawi
Department of Physiology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil; and.
Melina Pires
MP
da Silva
Department of Physiology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil; and Physiology Department, Georgia Regents University, Augusta, Georgia.
Wagner Luis
WL
Reis
Department of Physiology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil; and.
Ricardo
R
Coletti
Department of Physiology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil; and.
Juliana Bezerra Medeiros
JB
de Lima
Department of Physiology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil; and.
Lucila Leico Kagohara
LL
Elias
Department of Physiology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Sao Paulo, Brazil; and antunes@fmrp.usp.br.
Jose
J
Antunes-Rodrigues
D000818:Animals; D019898:Autocrine Communication; D002248:Carbon Monoxide / Q000378:metabolism*; D005740:Gases; D006801:Humans; D006862:Hydrogen Sulfide / Q000378:metabolism*; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism* / Q000503:physiopathology; D009569:Nitric Oxide / Q000378:metabolism*; D019899:Paracrine Communication; D015398:Signal Transduction; D014882:Water-Electrolyte Balance; D014883:Water-Electrolyte Imbalance / Q000378:metabolism* / Q000503:physiopathology
D005740:Gases; D009569:Nitric Oxide; D002248:Carbon Monoxide; D006862:Hydrogen Sulfide