Multimodality imaging of Epstein-Barr virus-associated inflammatory pseudotumor-like follicular dendritic cell tumor of the spleen: case report and literature review.
Inflammatory pseudotumors (IPTs) are rare tumors of unknown etiology; however, there is a strong association with the Epstein-Barr virus (EBV). EBV-positive IPTs are typically found in the liver and spleen. While many EBV-positive splenic IPTs contain follicular dendritic cell (FDC) proliferations, they are not aggressive such as with conventional FDC tumors. EBV-positive splenic IPTs have been reported with low malignant potential. We present a case with multimodality imaging of an EBV-positive IPT-like tumor with FDC features.
Department of Diagnostic Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030. Electronic address: pbui588@gmail.com.
Pauline L
PL
Bui
Department of Diagnostic Radiology, Unit 1473, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030-4009. Electronic address: RVicens@mdanderson.org.
Rafael A
RA
Vicens
Department of Lymphoma/Myeloma, Unit 0429, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030-4009.
Jason R
JR
Westin
Department of Diagnostic Radiology, Unit 1473, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030-4009. Electronic address: cjensen@mdanderson.org.
Corey T
CT
Jensen
D020566:Dendritic Cells, Follicular / Q000473:pathology*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006104:Granuloma, Plasma Cell / Q000175:diagnosis* / Q000209:etiology / Q000821:virology*; D004854:Herpesvirus 4, Human; D006801:Humans; D008279:Magnetic Resonance Imaging; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013154:Spleen / Q000473:pathology / Q000821:virology; D013158:Splenic Diseases / Q000175:diagnosis* / Q000821:virology*
D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
EBV; Epstein–Barr virus; IPT; Inflammatory pseudotumor; Splenic pseudotumor