Copper/palladium synergistic catalysis for the syn- and anti-selective carboboration of alkenes.
A method for the diastereoselective carboboration of 1,2-disubstituted styrenes with aryl/vinyl bromides and (Bpin)2 is reported. High diastereoselectivities and yields are observed for the formation of either diastereomer of the product from a single alkene isomer. These reactions provide access to a diverse range of structures from simple starting materials.
Department of Chemistry, Indiana University, 800 E. Kirkwood Ave. Bloomington, IN 47401 (USA).
Kaitlyn M
KM
Logan
Kevin B
KB
Smith
M Kevin
MK
Brown
carboboration; copper; cross-coupling; palladium; synergistic catalysis