Blood and lymphatic vessel formation.
Blood and lymphatic vessels deliver oxygen and nutrients, remove waste and CO2, and regulate interstitial pressure in tissues and organs. These vessels begin life early in embryogenesis using transcription factors and signaling pathways that regulate differentiation, morphogenesis, and proliferation. Here we describe how these vessels develop in the mouse embryo, and the signals that are important to their development.
Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
Victoria L
VL
Bautch
McAllister Heart Institute, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 Department of Cell and Molecular Physiology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599.
Kathleen M
KM
Caron
D000818:Animals; D001808:Blood Vessels / Q000196:embryology*; D002454:Cell Differentiation / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental / Q000502:physiology*; D053263:Gene Regulatory Networks; D042601:Lymphatic Vessels / Q000196:embryology*; D051379:Mice; D009024:Morphogenesis / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*