Predictive factors of recurrence and malignant transformation in vocal cord leukoplakia.
The aim of this study was to define the predictive risk factors of vocal cord leukoplakia recurrence and malignant transformation. From January 2009 to December 2013, 63 patients with a diagnosis of vocal cord leukoplakia were identified based on their medical records. The 63 patients comprised 62 males and one female. This study showed that the extent of vocal cord leukoplakia resulted in statistically significant differences for both the recurrence of vocal cord leukoplakia and malignant transformation (p < 0.05). In addition, this study revealed that the degree of dysplasia resulted in statistically significant differences for both the recurrence of vocal cord leukoplakia and malignant transformation (p < 0.05). We suggest that the extent of lesion and the degree of dysplasia are predictive factors for the risk of recurrence and malignant transformation.
Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Hwasun Hospital, 160 Ilsimri, Hwasun, Jeonnam, 519-809, South Korea, leen3l@hanmail.net.
Dong Hoon
DH
Lee
Tae Mi
TM
Yoon
Joon Kyoo
JK
Lee
Sang Chul
SC
Lim
D000368:Aged; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D004210:Dissection / Q000379:methods; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology / Q000601:surgery; D007818:Laryngeal Diseases / Q000473:pathology / Q000601:surgery; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000517:prevention & control; D007971:Leukoplakia / Q000473:pathology / Q000601:surgery; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D014827:Vocal Cords / Q000473:pathology / Q000601:surgery