Catalysing mirror life.
Origin of life: Although current life is homochiral (with D nucleic acids), little is known about how homochirality emerged or even if it was a necessary step. The isolation of cross-chiral nucleic acid ligases demonstrate that an early heterochiral life could have been possible.
Laboratory for Medicinal Chemistry, Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, 3000, Leuven (Belgium).
Marleen
M
Renders
Vitor B
VB
Pinheiro
D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D012313:RNA / Q000096:biosynthesis* / Q000737:chemistry*; D016337:RNA, Catalytic / Q000737:chemistry* / Q000378:metabolism*
D016337:RNA, Catalytic; D012313:RNA; D012321:DNA-Directed RNA Polymerases
RNA world; directed evolution; origin of life; ribozyme