Relationship of Caffeine with Adiponectin and Blood Sugar Levels in Subjects with and without Diabetes.
BACKGROUND
Coffee though not usually thought of as healthy food but can be treated as one of the beneficial drink. Many researchers have found strong evidence that coffee reduces the risk of several serious ailments, including diabetes, heart disease, cirrhosis of the liver, etc. The long term beneficial effect of coffee on diabetes is now understood to be more influential and obliging.


METHODS
This study comprised 220 healthy subjects of which 143 consumed coffee and 77 did not. These were matched with 90 diabetic subjects. Among the 90 diabetics, 48 consumed coffee and 42 did not consume coffee.


RESULTS
The mean adiponectin value was significantly higher in coffee consumed normal and diabetic subjects than the subjects who did not consume coffee. The decrease in fasting blood sugar and HbA1c values were also observed in normal and diabetic subjects who consumed coffee than the other groups who did not consume coffee. Significant difference (p<0.05) in mean FBG, PPBS, HbA1c and adiponectin were observed between coffee consumed and no coffee consumed groups.


CONCLUSIONS
The long term use of caffeine is more efficient on blood sugar and adiponectin levels, which needed in the prevention of complications in diabetic subjects.
Assistant Professor, Department of Biochemistry, Subbaiah Institute of Medical Science , Shimoga, Karnataka, India .
Geetha
G
Bhaktha
Professor, Department of Biochemistry, Subbaiah Institute of Medical Science , Shimoga, Karnataka, India; Faculty of Medical Sciences, The University of the West Indies, Trinidad .
B Shivananda
BS
Nayak
Associate Professor, Department of Statistics, Manipal University , Manipal, Karnataka, India .
Shreemathi
S
Mayya
Professor, Department of Biochemistry, Yenepoya Medical College , Yenepoya University, Mangalore, Karnataka, India .
Manjula
M
Shantaram
Adiponectin; Caffeine; Type 2 diabetes