Isolated extraocular muscle infiltration with plasmacytoma treated with localized injection of dexamethasone.
Plasmacytoma of the orbit secondary to multiple myeloma is rare and has not previously been reported limited to an extraocular muscle. Conventional treatment is either localized radiotherapy or systemic chemotherapy. We report a case of plasmacytoma within the medial rectus muscle, which regressed completely with localized infiltration of dexamethasone.
Oxford Eye Hospital (SLP), John Radcliffe Hospital, Oxford, United Kingdom; Department of Haematology (ED), Churchill Hospital, Oxford, United Kingdom; and Department of Ophthalmology (JSE), Oxford Eye Hospital, Oxford, United Kingdom.
Sally L
SL
Painter
Emmy
E
Dickens
John S
JS
Elston
D000368:Aged; D000911:Antibodies, Monoclonal / Q000378:metabolism; D015703:Antigens, CD / Q000378:metabolism; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D003907:Dexamethasone / Q000627:therapeutic use*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008544:Melanocytes / Q000378:metabolism / Q000473:pathology; D009801:Oculomotor Muscles / Q000187:drug effects* / Q000503:physiopathology*; D010954:Plasmacytoma / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D018931:Antineoplastic Agents, Hormonal; C100347:VS38 monoclonal antibody; D003907:Dexamethasone