Clinical characteristics of abnormal savda syndrome type in human immunodeficiency virus infection and acquired immune deficiency syndrome patients: A cross-sectional investigation in Xinjiang, China.
OBJECTIVE
To investigate the distribution of abnormal hilit syndromes in traditional Uighur medicine (TUM) among human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) patients, and to find out the clinical characteristics of abnormal savda syndrome type HIV/AIDS patients.


METHODS
Between June and July in 2012, 307 eligible HIV/AIDS patients from in-patient department and out-patient clinics of Xinjiang Uighur Autonomous Region the Sixth People's Hospital in Urumqi were investigated. TUM syndrome differentiation was performed by a senior TUM physician. Each participant completed a Sign and Symptom Check-List for Persons Living with HIV/AIDS (SSC-HIV) questionnaire. Depression was evaluated by using Hamilton Rating Scale for Depression Questionnaire. Blood specimen was collected from each participant to test the levels of blood chemicals.


RESULTS
Of 307 HIV/AIDS patients, 189 (61.6%) were abnormal savda syndrome type, 118 (38.4%) were non-abnormal-savda syndrome type. Mean CD4 counts of abnormal savda syndrome type patients was (227.61±192.93) cells/µL, and the prevalence of anemia, thrombocytopenia, and elevated cystatin C were 49.7%, 28.6%, and 44.7%, which were significantly higher than those in the non-abnormal-savda syndrome type patients (26.3%, 16.0% and 25.0%,P<0.05). In addition, depression (79.9%) and HIV/AIDS-related symptoms such as fatigue (42.3%), back aches (40.7%), lack of appetite (33.9%), night sweats (31.7%) were more common among abnormal savda syndrome patients (P<0.05).


CONCLUSIONS
Abnormal savda syndrome is the dominant syndrome among HIV/AIDS patients, and they present a more sever clinical manifestation.
Department of Epidemiology and Biostatistics, Xinjiang Medical University, Urumqi, 830011, China.
Mi-ji-ti
MJ
Peierdun
School of Traditional Uighur Medicine, Xinjiang Medical University, Urumqi, 830011, China.
Wen-xian
WX
Liu
School of Traditional Uighur Medicine, Xinjiang Medical University, Urumqi, 830011, China.
Ai-ze-zi
AZ
Renaguli
School of Traditional Uighur Medicine, Xinjiang Medical University, Urumqi, 830011, China.
Amat
A
Nurmuhammat
Xinjiang Uighur Autonomous Region the Sixth People's Hospital, Urumqi, 840013, China.
Xiao-chun
XC
Li
Xinjiang Uighur Autonomous Region the Sixth People's Hospital, Urumqi, 840013, China.
Ka-ha-er
KH
Gulibaier
Xinjiang Uighur Autonomous Region the Sixth People's Hospital, Urumqi, 840013, China.
Wu-la-mu
WL
Ainivaer
School of Traditional Uighur Medicine, Xinjiang Medical University, Urumqi, 830011, China. halmurat@263.net.
Upur
U
Halmurat
D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis*; D000328:Adult; D018791:CD4 Lymphocyte Count; D002681:China / Q000208:ethnology; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008519:Medicine, Traditional; D008875:Middle Aged; D011795:Surveys and Questionnaires
abnormal savda syndrome; depression; human immunodeficiency virus infection and acquired immune deficiency syndrome; symptoms; traditional Uighur medicine