[Mitral valve replacement for a manifesting carrier of duchenne muscular dystrophy].
Duchenne muscular dystrophy (DMD) is an X-linked disease, but female carriers infrequently have some symptoms, who are called manifesting carriers. Here we report a case of a manifesting carrier of DMD with skeletal muscle weakness and cardiac abnormalities such as deterioration of cardiac function and left ventricular dilatation, who successfully underwent cardiac surgery. A 79-year-old female with acute heart failure for severe mitral regurgitation was admitted to our hospital. Surgical replacement of the mitral valve was performed under general anesthesia with intravenous anesthetics and non-depolarizing muscle relaxant. Cardiac surgery on a manifesting carrier of DMD is rare and requires a careful preoperative assessment of the heart function and anesthetic management.
Department of Surgery II , Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Hirohito
H
Ishii
Kunihide
K
Nakamura
Hiroyuki
H
Nagahama
Masakazu
M
Matsuyama
Jouji
J
Endo
Masanori
M
Nishimura
D000368:Aged; D013504:Cardiovascular Surgical Procedures; D005260:Female; D006801:Humans; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D020388:Muscular Dystrophy, Duchenne / Q000150:complications / Q000601:surgery*