Fluorescence Behaviour of an Aluminium Octacarboxy Phthalocyanine--NaYGdF4:Yb/Er Nanoparticle Conjugate.
Using a methanol assisted thermal decomposition approach, sphere shaped NaYGdF4:Yb/Er upconversion nanoparticles (UCNPs) were successfully synthesized. The chemical, spectroscopic and fluorescence properties of the UCNPs were fully characterized. Characteristic upconversion fluorescence emissions were produced by the NPs in the green, red and NIR regions and the NPs were also shown to possess paramagnetic properties. The influence of the UCNPs on the spectroscopic and fluorescence properties of an aluminium octacarboxy phthalocyanine AlOCPc was investigated. Covalent conjugation to an AlOCPc resulted in a large blue shift of the phthalocyanine's Q band, which was accompanied by a decrease in the Pc's fluorescence lifetime in DMSO. By combining the phthalocyanine and upconversion nanoparticle, we present a system capable of multimodal imaging, using both the upconversion nanoparticle's and phthalocyanine's emission, and magnetic resonance imaging (as a result of doping the upconversion nanoparticles with Gd(3+) ions).
Department of Chemistry, Rhodes University, Grahamstown, 6140, South Africa.
Jessica
J
Taylor
Christian
C
Litwinski
Tebello
T
Nyokong
Edith
E
Antunes
D004871:Erbium / Q000737:chemistry*; D005453:Fluorescence; D005459:Fluorides / Q000737:chemistry; D005682:Gadolinium / Q000737:chemistry; D007211:Indoles / Q000737:chemistry*; D008279:Magnetic Resonance Imaging; D053758:Nanoparticles / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D019265:Spectroscopy, Near-Infrared; D015018:Ytterbium / Q000737:chemistry*; D015019:Yttrium / Q000737:chemistry*
D007211:Indoles; D009942:Organometallic Compounds; C060570:aluminum phthalocyanine; D015019:Yttrium; D004871:Erbium; D005682:Gadolinium; D015018:Ytterbium; D005459:Fluorides