[A case of stage IV gastric cancer resected after chemotherapy with capecitabine plus cisplatin].
A 64-year-old woman was diagnosed with Stage IV gastric cancer with lymph node and multiple liver metastases. She was treated with 6 courses of chemotherapy, in 3-week courses, with capecitabine (1,000 mg/m/(2)) plus cisplatin(80 mg/m(2)) administered for 2 weeks, followed by a drug-free week. She underwent curative total gastrectomy with D2 lymph node dissection and reconstruction by using the Roux-en-Y method. The postoperative pathological findings revealed a T3 (SE), N1M1, Stage II B tumor; the tumor was determined to be Grade 1b owing to the chemotherapeutic effect. Postoperatively, only S-1 therapy was administered, because of the development of Grade 3 hand-foot syndrome. The patient is alive 1 year and 8 months after the initial gastrectomy.
Dept. of Surgery, Yokohama City University.
Yoshiko
Y
Fujikawa
Tsutomu
T
Sato
Yasushi
Y
Rino
Mamoru
M
Uchiyama
Yosuke
Y
Atsumi
Amane
A
Kanazawa
Tsutomu
T
Hayashi
Shinichi
S
Hasegawa
Hiroshi
H
Tamagawa
Kazuhito
K
Tsuchida
Naoto
N
Yamamoto
Takashi
T
Oshima
Norio
N
Yukawa
Takaki
T
Yoshikawa
Munetaka
M
Masuda
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000069287:Capecitabine; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000031:analogs & derivatives; D005743:Gastrectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary; D008197:Lymph Node Excision; D008875:Middle Aged; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery
D003841:Deoxycytidine; D000069287:Capecitabine; D002945:Cisplatin; D005472:Fluorouracil