Clinical evaluation of autologous platelet-rich fibrin in the treatment of multiple adjacent gingival recession defects: a 12-month study.
Leukocyte- and platelet-rich fibrin (L-PRF) belongs to a new generation of platelet concentrates. There are limited numbers of studies focused on the use of L-PRF in gingival recession defects. This study evaluated the safety and effectiveness of using L-PRF membranes as a substitute for free connective tissue grafts (CTGs) as a treatment method for gingival recession defects. A total of 44 Miller Class I/II gingival recessions that were bilateral, adjacent, and greater than 3 mm in size were selected. Each recession site was randomly assigned to the test group (L-PRF) or the control group (CTG). After 12 months, root coverage was 76.63% and 77.36% in the L-PRF and CTG groups, respectively. It is suggested that L-PRF membrane may be an alternative graft material for treating multiple adjacent recessions greater than 3 mm in size without a requirement for additional surgery.
Mustafa
M
Tunalι
Hakan
H
Özdemir
Taner
T
Arabacι
Bahadir
B
Gürbüzer
Levent
L
Pikdöken
Erhan
E
Firatli
D001792:Blood Platelets / Q000378:metabolism*; D005337:Fibrin / Q000008:administration & dosage*; D005889:Gingival Recession / Q000628:therapy*; D006801:Humans; D011182:Postoperative Care
D005337:Fibrin