[Perianesthetic refractory anaphylactic shock with cefuroxime in a patient with history of penicillin allergy on multiple antihypertensive medications].
We report a case of perianesthetic refractory anaphylactic shock with cefuroxime in a patient with history of penicillin allergy on regular therapy with atenolol, losartan, prazosin and nicardipine. Severe anaphylactic shock was only transiently responsive to 10mL of (1:10000) epinephrine and needed norepinephrine and dopamine infusion. Supportive therapy with vasopressors and inotropes along with mechanical ventilation for the next 24hours resulted in complete recovery. She was successfully operated upon 2 weeks later with the same anesthetic drugs but intravenous ciprofloxacin as the alternative antibiotic for perioperative prophylaxis.
Tata Main Hospital, Department of Anesthesiology and Critical Care, Jamshedpur, Índia. Electronic address: debsanjay@gmail.com.
Deb Sanjay
DS
Nag
Tata Main Hospital, Department of Anesthesiology and Critical Care, Jamshedpur, Índia.
Devi Prasad
DP
Samaddar
Tata Main Hospital, Department of Anesthesiology and Critical Care, Jamshedpur, Índia.
Shashi
S
Kant
Tata Main Hospital, Department of Anesthesiology and Critical Care, Jamshedpur, Índia.
Pratap Rudra
PR
Mahanty
D000707:Anaphylaxis / Q000139:chemically induced*; D000758:Anesthesia; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D002444:Cefuroxime / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000150:complications / Q000209:etiology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008875:Middle Aged; D010406:Penicillins / Q000009:adverse effects; D012720:Severity of Illness Index
D000900:Anti-Bacterial Agents; D000959:Antihypertensive Agents; D010406:Penicillins; D002444:Cefuroxime
Anafilaxia; Anaphylaxis; Cefuroxima; Cefuroxime; Perianesthetic; Perianestésico