[Diversity of cutaneous bacteria decreases inflammation].
Human microbiota includes all microorganisms, saprophytes and pathogens that colonize our bodies. Recent advances in metagenomic analysis techniques have expanded our knowledge of the microbiota and fundamentally changed our view of its relationships with the immune system. The commensal flora appears to be essential to the development of the immune system, and the diversity of the microbiota is correlated with good health status of individuals. These findings open up new conceptual and therapeutic approaches in chronic inflammatory diseases.
Service immunologie clinique et allergologie, CH Lyon-Sud, 69495 Pierre-Bénite Cedex, France; Inserm U1111-CIRI; Université Claude-Bernard-Lyon I.
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Hacard
Service immunologie clinique et allergologie, CH Lyon-Sud, 69495 Pierre-Bénite Cedex, France; Inserm U1111-CIRI; Université Claude-Bernard-Lyon I; Department of Dermatology, University of California, San Francisco CA 94143-0511, United States.
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Nosbaum
Service immunologie clinique et allergologie, CH Lyon-Sud, 69495 Pierre-Bénite Cedex, France.
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Huynh
Service immunologie clinique et allergologie, CH Lyon-Sud, 69495 Pierre-Bénite Cedex, France; Inserm U1111-CIRI; Université Claude-Bernard-Lyon I.
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Nicolas
Service immunologie clinique et allergologie, CH Lyon-Sud, 69495 Pierre-Bénite Cedex, France; Inserm U1111-CIRI; Université Claude-Bernard-Lyon I. Electronic address: frederic.berard@chu-lyon.fr.
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Bérard
D006801:Humans; D007249:Inflammation / Q000276:immunology*; D064307:Microbiota; D012867:Skin / Q000382:microbiology*
Immune system; Inflammation; Microbiome; Peau; Skin; Système immunitaire