Postnatal outcomes of infants with gastroschisis: a 5-year follow-up in a tertiary referral center in Brazil.
OBJECTIVE
The aim of this study was to evaluate postnatal outcomes in fetuses with gastroschisis.


METHODS
This is a retrospective study (2009-2013) of patients with gastroschisis at the Hospital São Paulo (Federal University of São Paulo, Brazil).


RESULTS
A total of 44 infants with gastroschisis were examined. The mean maternal age was 21.1 years and mean gestational age at delivery was 36.1 weeks. Delivery occurred before 34 weeks in 13.6%, between 34 and 36 weeks and 6 d in 40.9%, and after 37 weeks in 45.5%. The mean birth weight was 2349 g, with 37.2% small-for-gestational age infants. The mean umbilical cord blood pH was 7.32. Bowel resection and delayed fascial closure was performed in 14.6% and 19.5%, respectively. The mean hospitalization time in the neonatal intensive care unit was 52.7 d. Neonatal infection was detected in 52.4%, with a positive blood culture; 77.3% of those cases were coagulase negative staphylococci. The overall rate of mortality was 25%; 18.2% before birth, 45.4% during the neonatal period, and 36.4% in infants. The main cause of postnatal death was septicemia (55.5%).


CONCLUSIONS
Despite advances in perinatal care and surgical techniques, infants with gastroschisis still present high rates of complications and death.
a Department of Obstetrics , Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP) , São Paulo-SP , Brazil.
Natália Silva
NS
Carvalho
a Department of Obstetrics , Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP) , São Paulo-SP , Brazil.
Talita Micheletti
TM
Helfer
a Department of Obstetrics , Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP) , São Paulo-SP , Brazil.
Priscila de Oliveira
Pde O
Serni
a Department of Obstetrics , Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP) , São Paulo-SP , Brazil.
Ohanna Ana
OA
Terasaka
a Department of Obstetrics , Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP) , São Paulo-SP , Brazil.
Tatiane
T
Boute
a Department of Obstetrics , Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP) , São Paulo-SP , Brazil.
Edward
E
Araujo Júnior
a Department of Obstetrics , Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP) , São Paulo-SP , Brazil.
Luciano Marcondes Machado
LM
Nardozza
a Department of Obstetrics , Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP) , São Paulo-SP , Brazil.
Antonio Fernandes
AF
Moron
a Department of Obstetrics , Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP) , São Paulo-SP , Brazil.
Liliam Cristine
LC
Rolo
D000293:Adolescent; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D020139:Gastroschisis / Q000150:complications / Q000401:mortality* / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011247:Pregnancy; D012189:Retrospective Studies; D018805:Sepsis / Q000209:etiology; D062606:Tertiary Care Centers / Q000706:statistics & numerical data; D055815:Young Adult
Fetal malformation; gastroschisis; infants; outcomes; postnatal; referral center