Efficacy of transurethral prostate enucleation by bipolar system for patients with benign prostatic hyperplasia.
BACKGROUND
The aim of this paper was to evaluate the efficacies and safety of transurethral prostate enucleation by bipolar system (TUEB) for the patients with benign prostatic hyperplasia (BPH).


METHODS
We prospectively evaluated clinical outcomes of TUEB in 55 patients with BPH from July 2005 to January 2011. Mean ages of the patients were 69.2 years. International Prostate Symptom Score (IPSS), IPSS-quality of life (IPSS-QOL) were assessed before and 12 months after surgery. Serum PSA, maximal flow rate (MFR), and post-void residual (PVR) were also evaluated before and 6 and 12 months after surgery.


RESULTS
The median prostate volumes and resection volumes were 64.1 g (interquartile range [IQR]: 48-87) and 34.4 g (25-60.2), respectively. The median operation time was 138.0 min (100.2-169.2). Total IPSS scores and IPSS-QOL were significantly improved (from 24 [17-31] to 5 [2-8] points, and from 6 [5-6] to 2 [1-2] points, both P<0.001). MFR and PVR were significantly improved 6 and 12 months after TUEB (from 6.2 [3.9-8.3] to 15.1 [10.5-20.9], and 14.6 [10.2-20.5] mL/s, P<0.0001, and from 151.5 [81.5-284.7] to 16.5 [0-30.5], and 6.0 [0-41.0] mL, P<0.0001, respectively). Serum PSA also significantly decreased, 6 and 12 months (from 7.5 [4.7-9.8] to 1.1 [0.5-1.5], and 0.6 [0.3-1.9] ng/mL, P<0.0001). Although hemoglobin decreased after operation, no case experienced blood transfusion. Three episodes of urinary tract infections, 14 cases of mild stress urinary incontinence, 2 cases of urinary retention were occurred transiently with recovery within 1 month after surgery.


CONCLUSIONS
We identified favorable efficacy and safety of TUEB. TUEB appears to be another possibility in the treatment of BPH.
Department of Urology, Nihon University School of Medicine, Tokyo, Japan - obinata.daisuke@nihon-u.ac.jp.
Katsuhiko
K
Sato
Daisuke
D
Obinata
Daigo
D
Funakoshi
Fuminori
F
Saito
Shogo
S
Takada
Akiko
A
Ito
Yasutaka
Y
Murata
Daisaku
D
Ashikari
Yuichiro
Y
Ikado
Tomohiro
T
Igarashi
Tsuyoshi
T
Matsui
Junichi
J
Mochida
Yataro
Y
Yamanaka
Kenya
K
Yamaguchi
Satoru
S
Takahashi
D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000601:surgery*; D020728:Transurethral Resection of Prostate / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods*; D016896:Treatment Outcome