Intensive intravenous regime for acute severe colitis.
Acute severe exacerbation of ulcerative colitis is a potentially life threatening medical emergency. The management of acute severe ulcerative colitis depends on early recognition and prompt initiation of intensive intravenous treatment along with continuous objective monitoring for possible medical failure. The intensive regime is the accepted standard of care. This includes primarily a) intravenous corticosteroids, b) intravenous supportive management, and d) intravenous antibiotics in instances. This review discusses the timing, duration and dosage of the intensive intravenous treatment including the evidence based protocol for effective monitoring to enable timely escalation to second line therapy & colectomy.
Rupa
R
Banerjee
Matthew
M
Philip
Shobna
S
Bhatia
D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003082:Colectomy; D003093:Colitis, Ulcerative / Q000188:drug therapy*; D005440:Fluid Therapy; D006801:Humans; D007262:Infusions, Intravenous; D018529:Nutritional Support; D016879:Salvage Therapy
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents