[A successful case with TS-1+CDDP chemotherapy for recurrent gastric cancer].
A 64-year-old woman underwent cholecystectomy for treatment of cholecystolithiasis in January 2005. Pathological examination rendered a diagnosis of gallbladder carcinoma. Wedge resection of the liver and dissection of the lymph nodes was performed. No tumor cells in either the liver nodule or lymph nodes were found during pathological examination. At 4 years after surgery, paraaortic lymph node recurrence was confirmed by computed tomography (CT). Gemcitabine was administered once weekly for the first 3 weeks in a monthly cycle, but the tumor continued to increase in size. Gemcitabine was then switched to TS-1, after which it was changed to cisplatin because of continued tumor growth. After 35 courses of chemotherapy, CT showed the disappearance of the paraaortic lymph node, and the patient achieved a complete response. She is currently free of disease at 9 years after surgery.
Dept. of Hepato-Gastrointestinal Surgery, Funabashi Central Hospital.
Takeshi
T
Ogasawara
Yasuhiro
Y
Ootsuka
Shigeharu
S
Nakano
Takashi
T
Shida
Satoru
S
Nomura
Mirei
M
Kin
Makoto
M
Takahashi
Teisuke
T
Komatsu
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D005706:Gallbladder Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D012008:Recurrence; D017640:Silicates / Q000008:administration & dosage; D014025:Titanium / Q000008:administration & dosage
D017640:Silicates; C103828:titanium silicide; D014025:Titanium; D002945:Cisplatin