Global and regional functional assessment of ischemic heart disease with cardiac MR imaging.
Cardiac MR imaging (CMR) combines assessment of myocardial function and tissue characterization, and is therefore ideally suited to evaluating patients with ischemic heart disease (IHD). This article discusses evaluation of left ventricular global function at CMR, reviewing the literature supporting global parameters in risk stratification and assessment of treatment response in IHD. Techniques for assessment of regional myocardial function are reviewed, and normal myocardial motion and fiber arrangement discussed. Despite barriers to clinical adoption, integration of this assessment into clinical routine should improve the ability to detect functional consequences of early myocardial structural alterations in patients with IHD.
Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 North Michigan Avenue, Suite 1600, Chicago, IL 60611, USA. Electronic address: collins@fsm.northwestern.edu.
Jeremy D
JD
Collins
D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000175:diagnosis*; D013318:Stroke Volume / Q000502:physiology; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*
Cardiac MR imaging; Ischemic heart disease; Myocardial motion; Myocardial strain; Myocardial systolic function; Myocardial velocities