The effect of severing a normal S1 nerve root to use for reconstruction of an avulsed contralateral lumbosacral plexus: a pilot study.
The aim of this study was to evaluate the feasibility of using the intact S1 nerve root as a donor nerve to repair an avulsion of the contralateral lumbosacral plexus. Two cohorts of patients were recruited. In cohort 1, the L4-S4 nerve roots of 15 patients with a unilateral fracture of the sacrum and sacral nerve injury were stimulated during surgery to establish the precise functional distribution of the S1 nerve root and its proportional contribution to individual muscles. In cohort 2, the contralateral uninjured S1 nerve root of six patients with a unilateral lumbosacral plexus avulsion was transected extradurally and used with a 25 cm segment of the common peroneal nerve from the injured leg to reconstruct the avulsed plexus. The results from cohort 1 showed that the innervation of S1 in each muscle can be compensated for by L4, L5, S2 and S3. Numbness in the toes and a reduction in strength were found after surgery in cohort 2, but these symptoms gradually disappeared and strength recovered. The results of electrophysiological studies of the donor limb were generally normal. Severing the S1 nerve root does not appear to damage the healthy limb as far as clinical assessment and electrophysiological testing can determine. Consequently, the S1 nerve can be considered to be a suitable donor nerve for reconstruction of an avulsed contralateral lumbosacral plexus.
Changzheng Hospital, The Second Military Medical University, 415 Fengyang Rd, Huangpu District, Shanghai, China.
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Zhu
Changzheng Hospital, The Second Military Medical University, 415 Fengyang Rd, Huangpu District, Shanghai, China.
F Zhang
Changzheng Hospital, The Second Military Medical University, 415 Fengyang Rd, Huangpu District, Shanghai, China.
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D
Yang
Changzheng Hospital, The Second Military Medical University, 415 Fengyang Rd, Huangpu District, Shanghai, China.
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A
Chen
D000293:Adolescent; D000328:Adult; D002648:Child; D004576:Electromyography; D005240:Feasibility Studies; D005260:Female; D050723:Fractures, Bone / Q000000981:diagnostic imaging; D006801:Humans; D007866:Leg / Q000294:innervation; D008160:Lumbosacral Plexus / Q000293:injuries / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016067:Nerve Transfer / Q000379:methods*; D010865:Pilot Projects; D012447:Sacrum / Q000000981:diagnostic imaging / Q000293:injuries; D012584:Sciatic Nerve / Q000293:injuries / Q000637:transplantation*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
Nerve transfer; sacral nerve plexus; reconstruction