The Nrf-2/ARE-HO-1 axis: An important therapeutic approach for attenuating myocardial ischemia and reperfusion injury-induced cardiac remodeling.
Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute of Wuhan University, Jiefang Road 238, Wuchang, 430060 Wuhan, PR China.
Jichun
J
Wang
Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute of Wuhan University, Jiefang Road 238, Wuchang, 430060 Wuhan, PR China.
Xiaorong
X
Hu
Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute of Wuhan University, Jiefang Road 238, Wuchang, 430060 Wuhan, PR China. Electronic address: jianghongwhu@163.com.
Hong
H
Jiang
D000818:Animals; D002265:Carboxylic Ester Hydrolases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D051547:Heme Oxygenase-1 / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006801:Humans; D017202:Myocardial Ischemia / Q000378:metabolism* / Q000517:prevention & control; D015425:Myocardial Reperfusion / Q000379:methods; D015428:Myocardial Reperfusion Injury / Q000378:metabolism* / Q000517:prevention & control; D051267:NF-E2-Related Factor 2 / Q000037:antagonists & inhibitors / Q000378:metabolism*; D020257:Ventricular Remodeling / Q000502:physiology*
D051267:NF-E2-Related Factor 2; C495635:NFE2L2 protein, human; C496541:HMOX1 protein, human; D051547:Heme Oxygenase-1; D002265:Carboxylic Ester Hydrolases; C019734:arylesterase
Cardiac remodeling; Heme oxygenase-1; Nuclear factor-erythroid-2 (NF-E2)-related factor 2