Giant Cell Tumor of the Larynx Treated by Surgery and Adjuvant Denosumab: Case Report and Review of the Literature.
Giant cell tumor of the larynx (GCTL) is a rare entity; only 34 cases have been reported in the literature. We report a case of GCTL in a 46 year-old male presenting clinical, radiographic, histological and therapeutic features. Previously reported cases are also reviewed.
Division of Oral and Maxillofacial Pathology, Department of Dental Medicine, Hofstra North Shore-LIJ School of Medicine, 270-05 76th Avenue, New Hyde Park, NY, 11040, USA. ayancosk12@nshs.edu.
Aaron E
AE
Yancoskie
Division of Head and Neck Surgery, Department of Otolaryngology, Hofstra North Shore-LIJ School of Medicine, 270-05 76th Avenue, New Hyde Park, NY, 11040, USA.
Douglas K
DK
Frank
Division of Oral and Maxillofacial Pathology, Department of Dental Medicine, Hofstra North Shore-LIJ School of Medicine, 270-05 76th Avenue, New Hyde Park, NY, 11040, USA.
John E
JE
Fantasia
The Monter Cancer Center, Hofstra School of Medicine, 450 Lakeville Road, Lake Success, NY, 11042, USA.
Steven
S
Savona
Internal Med-Hematology Onc, Hofstra North Shore-LIJ School of Medicine, 270-05 76th Avenue, New Hyde Park, NY, 11040, USA.
Nicole
N
Eiseler
Department of Pathology, Hofstra North Shore-LIJ School of Medicine, 270-05 76th Avenue, New Hyde Park, NY, 11040, USA.
Ilan
I
Reder
Department of Pathology, Hofstra North Shore-LIJ School of Medicine, 270-05 76th Avenue, New Hyde Park, NY, 11040, USA.
Leonard B
LB
Kahn
D000970:Antineoplastic Agents / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D000069448:Denosumab / Q000627:therapeutic use; D005870:Giant Cell Tumors / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D013517:Otorhinolaryngologic Surgical Procedures
D000970:Antineoplastic Agents; D000069448:Denosumab
Denosumab; Giant cell; Head and neck surgery; Larynx