Hyperthermia in the treatment of recurrent abdominal desmoid tumor.
The most suitable management of recurrent abdominal desmoid tumor is still unclear. A case of recurrent huge abdominal desmoid tumor successfully treated by hyperthermia therapy is described. A 63-year-old man was operated upon for desmoid tumor in the retroperitoneum involving pancreas, posterior wall of the stomach and transverse mesocolon in 2007. In 2008, the tumor recurred and could not be resected because of the patient refused the operation. Several therapies using tamoxifen, anastrozole, imatinib mesylate and radiotherapy were all ineffective. The tumor grew bigger and bigger during a treatment period. Finally, hyperthermia treatment was applied to the tumor. The size of the recurrent desmoid tumor reduced 75% by hyperthermia treatment for 46-month. Base on this experience, we recommend hyperthermia as the treatment for patients with recurrent abdominal desmoid tumor that several therapeutic strategies did not achieve a remarkable response.
Dept. of Surgery, Kurume University School of Medicine.
Hiroto
H
Ishikawa
Hiroaki
H
Hirakawa
Kenjiro
K
Takahashi
Yusuke
Y
Kawashima
Takeshi
T
Yoshida
Taro
T
Isobe
Satoru
S
Matono
Ryuichi
R
Kawahara
Toru
T
Hisaka
Hiroyuki
H
Horiuchi
Masamichi
M
Nakayama
Yoshinobu
Y
Okabe
Yoshiyasu
Y
Yamatsu
Hirohisa
H
Yano
Yoshito
Y
Akagi
D000008:Abdominal Neoplasms / Q000628:therapy*; D018222:Desmoid Tumors / Q000628:therapy*; D006801:Humans; D006979:Hyperthermia, Induced; D008297:Male; D012008:Recurrence; D014057:Tomography, X-Ray Computed