Subliminal galvanic-vestibular stimulation recalibrates the distorted visual and tactile subjective vertical in right-sided stroke.
Stroke of the right cerebral hemisphere often causes deficits in the judgement of the subjective visual vertical (SVV) and subjective tactile vertical (STV) which are related to central vestibular functioning. Clinically, deficits in the SVV/STV are linked to balance problems and poor functional outcome. Galvanic Vestibular Stimulation (GVS) is a non-invasive, save stimulation technique that induces polarity-specific changes in the cortical vestibular systems. Subliminal GVS induces imperceptible vestibular stimulation without unpleasant side effects. Here, we applied bipolar subliminal GVS over the mastoids (mean intensity: 0.7 mA, 20 min duration per session) to investigate its online-influence on constant errors, difference thresholds and range values in the SVV and STV. 24 patients with subacute, single, unilateral right hemisphere stroke were studied and assigned to two patient groups (impaired vs. normal in the SVV and STV) on the basis of cut-off scores from healthy controls. Both groups performed these tasks under three experimental conditions on three different days: a) sham GVS where electric current was applied only for 30s and then turned off, b) left-cathodal GVS and c) right-cathodal GVS, for a period of 20 min per session. Left-cathodal GVS, but not right-cathodal GVS significantly reduced all parameters in the SVV. Concerning STV GVS also reduced constant error and range numerically, though not significantly. These effects occurred selectively in the impaired patient group. In conclusion, we found that GVS rapidly influences poststroke verticality deficits in the visual and tactile modality, thus highlighting the importance of the vestibular system in the multimodal elaboration of the subjective vertical.
Clinical Neuropsychology Unit & Outpatient Department, Saarland University, Saarbruecken, Germany.
Karin
K
Oppenländer
Department of Neurology, University of Erlangen-Nuremberg, Germany.
Kathrin S
KS
Utz
Clinical Neuropsychology Unit & Outpatient Department, Saarland University, Saarbruecken, Germany.
Stefan
S
Reinhart
Schön Clinic, Bad Aibling, Germany.
Ingo
I
Keller
Clinical Neuropsychology Unit & Outpatient Department, Saarland University, Saarbruecken, Germany.
Georg
G
Kerkhoff
Clinical Neuropsychology Unit & Outpatient Department, Saarland University, Saarbruecken, Germany. Electronic address: annakatharina.schaadt@uni-saarland.de.
Anna-Katharina
AK
Schaadt
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D004558:Electric Stimulation / Q000379:methods*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010468:Perceptual Disorders / Q000209:etiology / Q000534:rehabilitation*; D010775:Photic Stimulation; D020521:Stroke / Q000150:complications; D014110:Touch / Q000502:physiology*; D014722:Vestibule, Labyrinth / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*
Multimodal; Space perception; Stroke; Treatment; Vertical