Parietal bone osteomyelitis in melioidosis.
We report a case of a 55-year-old man with uncontrolled diabetes who presented with pneumonia. During his hospital stay his clinical status worsened and he had a focal seizure. MRI showed central nervous system involvement and parietal bone osteomyelitis. As the patient's blood culture and endotracheal aspirate grew Burkholderia pseudomallei, melioidosis was diagnosed. He was treated with meropenem after failure to respond to ceftazidime. He gradually improved over a period of 4 weeks and was discharged. Early diagnosis and therapy resulted in improved outcome.
Department of Internal Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Hariprasad Sadanand
HS
Shetty
Department of Internal Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Ajay Raj
AR
Mallela
Department of Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Barkur Ananthakrishna
BA
Shastry
Department of Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.
Vasudeva
V
Acharya
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D048909:Diabetes Complications; D003937:Diagnosis, Differential; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008554:Melioidosis / Q000175:diagnosis* / Q000188:drug therapy; D000077731:Meropenem; D008875:Middle Aged; D010019:Osteomyelitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D010294:Parietal Bone / Q000382:microbiology*; D013845:Thienamycins / Q000627:therapeutic use; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D013845:Thienamycins; D000077731:Meropenem