Diphyllobothrium nihonkaiense infections in a family.
Diphyllobothrium latum and Diphyllobothrium nihonkaiense are morphologically similar to each other, and only genetic method can differentiate clearly between the 2 species. A strobila of diphyllobothriid tapeworm discharged from a 7-year-old boy was analyzed to identify the species by mitochondrial cytochrome c oxidase subunit 1 (cox1) gene sequencing. He and his family (total 4 persons) ate slices of 3 kinds of raw fish 16 days before visiting our outpatient clinic. All family members complained of abdominal pain and watery diarrhea. They all expelled tapeworm strobilae in their stools. They were treated with a single oral dose of praziquantel and then complained of no more symptoms. The cox1 gene sequencing of the strobila from the boy revealed 99.9% (687/688 bp) similarity with D. nihonkaiense and only 93.2% (641/688 bp) similarity with D. latum. Thus, we assigned this tapeworm as D. nihonkaiense. This is the first report of D. nihonkaiense infection in a family in Korea, and this report includes the 8th pediatric case in Korea. The current report is meaningful because D. nihonkaiense infection within a family is rare.
Department of Pediatrics, Myongji Hospital, Goyang 412-826, Korea.
Young Bin
YB
Go
Department of Pediatrics, Myongji Hospital, Goyang 412-826, Korea.
Eun Hye
EH
Lee
Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.
Jaeeun
J
Cho
Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.
Seoyun
S
Choi
Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.
Jong-Yil
JY
Chai
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D002648:Child; D004169:Diphyllobothriasis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology*; D004170:Diphyllobothrium / Q000145:classification* / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D003576:Electron Transport Complex IV / Q000235:genetics; D005192:Family Health; D006801:Humans; D007723:Korea; D008297:Male; D011223:Praziquantel / Q000627:therapeutic use; D017422:Sequence Analysis, DNA; D016896:Treatment Outcome
D000871:Anthelmintics; D011223:Praziquantel; D003576:Electron Transport Complex IV
Diphyllobothrium latum; Diphyllobothrium nihonkaiense; cox1 gene; praziquantel; raw fish; tapeworm