Sepsis and septic shock: a review.
Sepsis and septic shock are a continuum of disease resulting from a complex host response to infection. They are major health issues in the United States, causing significant financial burden to the health care system in addition to multisystem morbidity and high rates of mortality. In recent decades, landmark trials in sepsis management have demonstrated improved mortality. Although the value of protocol-driven care is currently under question, it is clear that early recognition, prompt resuscitation, and timely use of antibiotics are of utmost importance.
Division of Pulmonary and Critical Care, Allegheny General Hospital, Pittsburgh, Pennsylvania.
Josebelo
J
Chong
Tiffany
T
Dumont
Lyndave
L
Francis-Frank
Marvin
M
Balaan
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D006801:Humans; D018805:Sepsis / Q000503:physiopathology; D012772:Shock, Septic / Q000503:physiopathology; D018746:Systemic Inflammatory Response Syndrome / Q000188:drug therapy / Q000401:mortality / Q000503:physiopathology*; D014481:United States
D000900:Anti-Bacterial Agents