[Renoprotective effects of statins under the conditions of acute renal failure, caused by rhabdomyolysis].
The experiment on white rats was targeted at the examination of influence of statins (atorvastatin, lovastatin, simvastatin) under the conditions of acute renal failure, caused by rhabdomyolysis. Renoprotective effects of statins were demonstrated by reduction of hyperazotemia and proteinuria and improvement of renal excretory function, which correlated with antioxidant properties of drugs.
I I
II
Zamorskiĭ
V G
VG
Zeleniuk
D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000209:etiology / Q000652:urine; D000818:Animals; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000493:pharmacokinetics*; D007668:Kidney / Q000378:metabolism*; D008297:Male; D011507:Proteinuria / Q000188:drug therapy / Q000209:etiology / Q000652:urine; D051381:Rats; D020127:Recovery of Function; D012206:Rhabdomyolysis / Q000150:complications / Q000188:drug therapy* / Q000652:urine
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors