The accessory limb model: an alternative experimental system of limb regeneration.
Accessory limb model (ALM) was developed as an experimental model and functional assay for limb regeneration. The ALM provides several ways to identify pathways and test for signaling molecules that regulate limb regeneration. Here, we summarize the history of the ALM and describe the specific details involved in inducing ectopic blastemas and limbs from a skin wound on the side of the arm.
Division of Liberal Arts and Sciences, Aichi Gakuin University, Nissin, Aichi, 470-0195, Japan.
Tetsuya
T
Endo
David M
DM
Gardiner
Aki
A
Makanae
Akira
A
Satoh
D000327:Adsorption; D000558:Ambystoma mexicanum / Q000502:physiology*; D000822:Animal Husbandry; D000818:Animals; D005121:Extremities / Q000502:physiology*; D008863:Microspheres; D023421:Models, Animal; D010641:Phenotype; D011506:Proteins / Q000737:chemistry; D012038:Regeneration; D012867:Skin / Q000166:cytology / Q000293:injuries / Q000294:innervation; D016038:Skin Transplantation
D011506:Proteins