Food allergens inducing a lymphocyte-mediated immunological reaction in canine atopic-like dermatitis.
Canine atopic-like dermatitis (ALD) is suspected to be associated with food allergies, particularly those mediated by lymphocytes. In this study, 54 cases were included as ALD dogs, based on the negative IgE test results. In the dogs, the percentage of activated cells in helper-T lymphocytes was measured by flow cytometry using cultured peripheral lymphocytes under food allergen stimulation. We observed that 49 of the 54 ALD dogs (90.7%) had positive lymphocyte reactions against one or more food allergens. The most common food allergen was soybean, showing positive results in 21 dogs (42.9%), while the allergen to cause the lowest number of reactions was catfish (only 5 dogs, 10.2%). These results may be useful in considering elimination diets for ALD dogs.
Suto Animal Hospital, 2-29-8 Horie, Urayasu-city, Chiba 279-0041, Japan.
Akemi
A
Suto
Yukinori
Y
Suto
Nozomi
N
Onohara
Yu
Y
Tomizawa
Yukiko
Y
Yamamoto-Sugawara
Taro
T
Okayama
Kenichi
K
Masuda
D000485:Allergens / Q000276:immunology*; D000818:Animals; D003876:Dermatitis, Atopic / Q000662:veterinary*; D004283:Dog Diseases / Q000276:immunology*; D004285:Dogs; D005260:Female; D005434:Flow Cytometry; D005512:Food Hypersensitivity / Q000662:veterinary*; D007111:Immunity, Cellular; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D006377:T-Lymphocytes, Helper-Inducer / Q000502:physiology*
D000485:Allergens