Helix-helix interactions: is the medium the message?
In this issue of Structure, Zhang and colleagues compare the helix-helix interaction spaces of an extensive database of soluble and membrane proteins. Intriguingly, the resultant clusters show similar helix interaction geometries between the protein classes, differing in detail only by patterns of local interactions and inter-helical distances.
Division of Molecular Structure and Function, Research Institute, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: deber@sickkids.ca.
Charles M
CM
Deber
Division of Molecular Structure and Function, Research Institute, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada.
Derek P
DP
Ng
D008565:Membrane Proteins / Q000737:chemistry*
D008565:Membrane Proteins