[A case of MALT lymphoma of the colon, stomach, and small intestine].
An 85-year-old man was diagnosed with mucosa-associated lymphoid tissue (MALT) lymphoma of the colon in 20XX. Although Helicobacter pylori eradication was performed as part of the treatment, it was ineffective. He was followed-up by colonoscopy for 4 years without additional treatment and there was no interval change;however, he was lost to follow-up 6 years after the first visit. Nine years after the initial diagnosis, he presented with new MALT lymphoma lesions in the stomach and small intestine. Genetic analysis showed that a biopsy specimen was positive for API2/MALT1 fusion gene, and IgH rearrangement showed monoclonal banding between colon and stomach. This suggested disseminated monoclonal API2/MALT1-positive MALT lymphoma of the colon, stomach, and small intestine. Careful attention should be paid to the appearance of multiple lesions in MALT lymphoma.
Department of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital.
Kota
K
Sahara
Taku
T
Tabata
Takeo
T
Arakawa
Takashi
T
Fujiwara
Hideto
H
Egashira
Junko
J
Fujiwara
Kumiko
K
Momma
Tsunekazu
T
Hishima
Koichi
K
Koizumi
Terumi
T
Kamisawa
D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000175:diagnosis*; D006801:Humans; D007414:Intestinal Neoplasms / Q000175:diagnosis*; D007421:Intestine, Small; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis* / Q000235:genetics; D008297:Male; D013274:Stomach Neoplasms / Q000175:diagnosis*