Homeostatic restoration of desmoplastic stroma rather than its ablation slows pancreatic cancer progression.
Epigenetics Unit, Department of Surgery and Cancer, Imperial College London, London, United Kingdom.
Fieke E M
FE
Froeling
Centre for Tumour Biology, Barts Cancer Institute - a CR-UK Centre of Excellence, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Hemant M
HM
Kocher
D000230:Adenocarcinoma / Q000188:drug therapy*; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002117:Calcitriol / Q000031:analogs & derivatives*; D021441:Carcinoma, Pancreatic Ductal / Q000188:drug therapy*; D006801:Humans; D010190:Pancreatic Neoplasms / Q000188:drug therapy*; D018167:Receptors, Calcitriol / Q000378:metabolism*
D000970:Antineoplastic Agents; D018167:Receptors, Calcitriol; D002117:Calcitriol