The baroreflex as a long-term controller of arterial pressure.
Because of resetting, a role for baroreflexes in long-term control of arterial pressure has been commonly dismissed in the past. However, in recent years, this perspective has changed. Novel approaches for determining chronic neurohormonal and cardiovascular responses to natural variations in baroreceptor activity and to electrical stimulation of the carotid baroreflex indicate incomplete resetting and sustained responses that lead to long-term alterations in sympathetic activity and arterial pressure.
Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi; and tlohmeier@umc.edu.
Thomas E
TE
Lohmeier
Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi; and Department of Physiology, University of Medicine and Pharmacology, Gr. T. Popa, Iasi, Romania.
Radu
R
Iliescu
D000818:Animals; D000959:Antihypertensive Agents / Q000627:therapeutic use; D062186:Arterial Pressure / Q000187:drug effects; D017704:Baroreflex / Q000187:drug effects; D002319:Cardiovascular System / Q000294:innervation*; D006706:Homeostasis; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D040542:Mechanotransduction, Cellular; D008955:Models, Cardiovascular; D009765:Obesity / Q000150:complications / Q000503:physiopathology; D011311:Pressoreceptors / Q000187:drug effects / Q000502:physiology*; D012084:Renin-Angiotensin System; D013997:Time Factors
D000959:Antihypertensive Agents