Language lateralization in a patient with temporal lobe epilepsy and callosal agenesis.
The corpus callosum has been proposed as a mechanism of interhemispheric inhibition that allows language dominance to develop [1]. Callosal agenesis or dysgenesis provides a test of this hypothesis, as patients lacking a normal corpus callosum should also lack normal language lateralization [2]. We report pre- and postoperative functional magnetic resonance imaging (fMRI) and neuropsychological testing in a patient with partial callosal agenesis who underwent a right temporal lobectomy for medically refractory seizures.
Department of Neurology, SKMC, United Arab Emirates.
Taoufik
T
Alsaadi
Department of Psychiatry, SKMC, United Arab Emirates.
Tarek M
TM
Shahrour
Callosal agenesis; Epilepsy; Language lateralization; fMRI