Evaluation of changes of intracranial blood flow after carotid artery stenting using digital subtraction angiography flow assessment.
OBJECTIVE
To evaluate the changes of intracranial blood flow after carotid artery stenting (CAS), using the flow assessment application "Flow-Insight", which was developed in our department.


METHODS
Twenty patients treated by CAS participated in this study. We analyzed the change in concentration of the contrast media at the anterior-posterior and profile view image with the flow assessment application "Flow-Insight". And we compared the results with N-isopropyl-p-[123I] iodoamphetamine-single-photon emission computed tomography (IMP SPECT) performed before and after the treatment.


RESULTS
From this study, 200% of the parameter "blood flow" change in the post/pre-treatment is suggested as the critical line of the hyperperfusion syndrome arise. Although the observed blood flow increase in the digital subtraction angiography system did not strongly correlate with the rate of increase of SPECT, the "Flow-Insight" reflected the rate of change of the vessels well. However, for patients with reduced reserve blood flow before CAS, a highly elevated site was in agreement with the site analysis results.


CONCLUSIONS
We concluded that the cerebral angiography flow assessment application was able to more finely reveal hyperperfusion regions in the brain after CAS compared to SPECT.
Hajime Wada, Masato Saito, Kyousuke Kamada, Department of Neurosurgery, Asahikawa Medical University, Asahikawa, Hokkaido 0788510, Japan.
Hajime
H
Wada
Hajime Wada, Masato Saito, Kyousuke Kamada, Department of Neurosurgery, Asahikawa Medical University, Asahikawa, Hokkaido 0788510, Japan.
Masato
M
Saito
Hajime Wada, Masato Saito, Kyousuke Kamada, Department of Neurosurgery, Asahikawa Medical University, Asahikawa, Hokkaido 0788510, Japan.
Kyousuke
K
Kamada
Carotid artery stenting; Cerebral angiography; Intracranial blood flow; Single-photon emission computed tomography