Recent advancements in carbon nanofiber and carbon nanotube applications in drug delivery and tissue engineering.
Since the discovery and synthesis of carbon nanotubes (CNTs) and carbon nanofibers (CNFs) over a decade ago, researchers have envisioned and discovered new potential applications for these materials. CNTs and CNFs have rapidly become a platform technology for a variety of uses, including biomedical applications due to their mechanical, electrical, thermal, optical and structural properties. CNTs and CNFs are also advantageous due to their ability to be produced in many different shapes and sizes. Since their discovery, of the many imaginable applications, CNTs and CNFs have gained a significant amount of attention and therapeutic potential in tissue engineering and drug delivery applications. In recent years, CNTs and CNFs have made significant contributions in designing new strategies for, delivery of pharmaceuticals, genes and molecular probes into cells, stem cell therapies and assisting in tissue regeneration. Furthermore, it is widely expressed that these materials will significantly contribute to the next generation of health care technologies in treating diseases and contributing to tissue growth. Hence, this review seeks to explore the recent advancements, current status and limitations of CNTs and CNFs for drug delivery and tissue engineering applications.
Department of Mechanical and Aerospace Engineering, California State University, Long Beach, Long Beach CA 90840 USA. David.Stout@csulb.edu.
David A
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D000818:Animals; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D057139:Nanofibers / Q000008:administration & dosage / Q000627:therapeutic use*; D037742:Nanotubes, Carbon; D009416:Nerve Regeneration / Q000187:drug effects; D023822:Tissue Engineering / Q000379:methods*
D037742:Nanotubes, Carbon