Ceftaroline in Combination With Trimethoprim-Sulfamethoxazole for Salvage Therapy of Methicillin-Resistant Staphylococcus aureus Bacteremia and Endocarditis.
No clinical trials have investigated the use of ceftaroline fosamil for salvage therapy of methicillin-resistant Staphylococcus aureus bacteremia and endocarditis. We report data on 29 patients who received ceftaroline ± another antimicrobial for this indication. Ninety percent of patients had microbiologic cure and 31% had treatment success with a median follow-up of 6 months.
Division of Infectious Diseases , Johns Hopkins University School of Medicine , Baltimore, Maryland.
Valeria
V
Fabre
Division of Infectious Diseases , Johns Hopkins University School of Medicine , Baltimore, Maryland ; Critical Care Medicine Department, National Institutes of Health, Bethesda, Maryland.
Marcela
M
Ferrada
Department of Pharmacy , Intermountain Medical Center , Murray, Utah.
Whitney R
WR
Buckel
Department of Pharmacy , Johns Hopkins Hospital , Baltimore, Maryland.
Edina
E
Avdic
Division of Infectious Diseases , Johns Hopkins University School of Medicine , Baltimore, Maryland.
Sara E
SE
Cosgrove
MRSA; bacteremia; ceftaroline fosamil; salvage