Comorbidity of bipolar disorder and eating disorders.
BACKGROUND
The comorbidity of bipolar disorder and eating disorders has not been studied in depth. In addition, clinical implications involved in the appearance of both disorders are very important.


METHODS
A systematic literature review of MEDLINE published up to September 2013 was performed, analyzing all the articles that studied the comorbidity of both conditions (bipolar disorder and eating disorders) and others research that studied the efficacy of pharmacological treatment and psychotherapy to improve these illnesses.


RESULTS
In this review we found a high comorbidity of bipolar disorder and eating disorders, especially of bulimia nervosa and binge eating disorder. Studies show that lithium and topiramate are 2 of the more effective pharmacological agents in the treatment of both disorders.


CONCLUSIONS
There are a lot of studies that show evidence of comorbidity of bipolar disorder and eating disorders. However, further research is needed on assessment and treatment when these conditions co-exist, as well as study into the biopsychological aspects to determine the comorbid aetiology.
Facultad de Psicología, Universidad de Granada, Granada, España.
Eva M
EM
Álvarez Ruiz
Grupo de investigación en Psiquiatría y Neurociencias (CTS-549), Instituto de Neurociencias, Universidad de Granada, Granada, España; Hospital Clínico San Cecilio, Servicio Andaluz de Salud, Granada, España. Electronic address: gutierrezrojasl@hotmail.com.
Luis
L
Gutiérrez-Rojas
D001714:Bipolar Disorder / Q000188:drug therapy / Q000453:epidemiology*; D002491:Central Nervous System Agents / Q000627:therapeutic use; D015897:Comorbidity; D001068:Feeding and Eating Disorders / Q000188:drug therapy / Q000453:epidemiology*; D005632:Fructose / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D000077236:Topiramate
D002491:Central Nervous System Agents; D000077236:Topiramate; D005632:Fructose; D008094:Lithium
Bipolar disorder; Comorbidity; Comorbilidad; Eating disorder; Trastorno bipolar; Trastornos de la conducta alimentaria