Group B streptococcal meningitis in children beyond the neonatal period in sub-Himalayan India.
OBJECTIVE
To evaluate clinicolaboratory profile and the outcomes in children (1 to 59 months) diagnosed with Group B streptococcus (GBS) meningitis over a period of 1 year.


METHODS
Cerebrospinal fluid (CSF) samples of 250 pediatric patients (1 to 59 months) admitted with suspected acute bacterial meningitis(ABM)were subjected to cell count, biochemical profile, culture, latex particle agglutination (LPA) and polymerase chain reaction (PCR). They were also evaluated for complications and were followed-up till 6 months after discharge.


RESULTS
Forty patients (25 boys and 15 girls), 16% of total suspected cases of ABM were diagnosed with GBS by LPA method and 30 (75%) out of these were above 3 months of age. The median duration of hospital stay was 7 days (range 1 to 72 days). State of coma was observed in two (5%) and one (2.5%) died, while 20 (50%) patients recovered completely.


CONCLUSIONS
GBS should be considered as an important cause of ABM in Indian children beyond the neonatal period and further studies are warranted to determine the actual problem of the disease in our country.
Department of Microbiology, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India.
Divya
D
Chauhan
Department of Microbiology, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India.
Kiran
K
Mokta
Department of Microbiology, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India.
Anil
A
Kanga
Department of Pediatrics, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India.
Neelam
N
Grover
Department of Microbiology, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India.
Digvijay
D
Singh
Department of Microbiology, Indira Gandhi Medical College and Hospital, Shimla, Himachal Pradesh, India.
Suruchi
S
Bhagra
Acute bacterial meningitis; group B streptococcus; latex particle agglutination; neonatal mortality