Fracture healing: fracture healing understood as the result of a fascinating cascade of physical and biological interactions. Part II.
Based on our own observations an explanation of the different factors influencing bone reaction is proposed. Special attention is given to the aspect of tissue deformation (strain). We propose thinking in terms of strain rather than of instability when contemplating tissue reaction. Considering the observed bone behavior should help improving the treatment of fractures and their complications.
AO Research Institute Davos, Switzerland.
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Perren
D005593:Fracture Fixation, Internal / Q000295:instrumentation; D017102:Fracture Healing / Q000502:physiology*; D050723:Fractures, Bone / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D016268:Internal Fixators; D016459:Prosthesis-Related Infections / Q000503:physiopathology; D012008:Recurrence; D013314:Stress, Mechanical