Screening for Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium should it be integrated into routine pregnancy care in French young pregnant women?
Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium screening during pregnancy is not performed routinely in France. We conducted the first prospective study in 1004 women attending for routine antenatal care to determine the prevalence and risk factors for these bacterial infections. The overall prevalence of C. trachomatis, N. gonorrhoeae, and M. genitalium infections was 2.5%, 0%, and 0.8%, respectively. In patients aged 18-24 years, the prevalence increased to 7.9% for C. trachomatis and to 2.4% for M. genitalium. C. trachomatis infection was associated with age ≤24 years or being single or having more than 5 sexual partners in a lifetime. M. genitalium infection was more frequent in patients aged ≤24 years or who had a history of abortion or their first sexual intercourse after 20 years of age. The high prevalence of C. trachomatis in pregnant women aged ≤24 years, mostly asymptomatic, suggests that systematic screening could be beneficial.
Univ. Bordeaux, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France; INRA, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France; Centre Hospitalier Universitaire de Bordeaux, Laboratoire de Bactériologie, 33076 Bordeaux, France. Electronic address: olivia.peuchant@u-bordeaux.fr.
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Peuchant
Univ. Bordeaux, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France; INRA, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France.
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Le Roy
Centre Hospitalier Universitaire de Bordeaux, Service de Gynécologie Obstétrique, 33076 Bordeaux, France.
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Desveaux
Centre Hospitalier Universitaire de Bordeaux, Service de Gynécologie Obstétrique, 33076 Bordeaux, France.
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Paris
Centre Hospitalier Universitaire de Bordeaux, Unité de Soutien Méthodologique à la Recherche Clinique et Epidémiologique, 33076 Bordeaux, France.
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Asselineau
Centre Hospitalier Universitaire de Bordeaux, Unité de Soutien Méthodologique à la Recherche Clinique et Epidémiologique, 33076 Bordeaux, France.
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Maldonado
Centre Hospitalier Universitaire de Bordeaux, Unité de Soutien Méthodologique à la Recherche Clinique et Epidémiologique, 33076 Bordeaux, France.
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Chêne
Centre Hospitalier Universitaire de Bordeaux, Service de Gynécologie Obstétrique, 33076 Bordeaux, France.
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Horovitz
Centre Hospitalier Universitaire de Bordeaux, Service de Gynécologie Obstétrique, 33076 Bordeaux, France.
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Dallay
Univ. Bordeaux, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France; INRA, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France; Centre Hospitalier Universitaire de Bordeaux, Laboratoire de Bactériologie, 33076 Bordeaux, France.
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de Barbeyrac
Univ. Bordeaux, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France; INRA, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, 33076 Bordeaux, France; Centre Hospitalier Universitaire de Bordeaux, Laboratoire de Bactériologie, 33076 Bordeaux, France.
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Bébéar
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002690:Chlamydia Infections / Q000175:diagnosis / Q000453:epidemiology*; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D003955:Diagnostic Tests, Routine / Q000379:methods*; D005260:Female; D005602:France / Q000453:epidemiology; D006069:Gonorrhea / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D009175:Mycoplasma Infections / Q000175:diagnosis / Q000453:epidemiology*; D045704:Mycoplasma genitalium / Q000302:isolation & purification; D009344:Neisseria gonorrhoeae / Q000302:isolation & purification; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D011296:Prenatal Diagnosis / Q000379:methods*; D015995:Prevalence; D011446:Prospective Studies; D055815:Young Adult
Chlamydia trachomatis; Mycoplasma genitalium; Neisseria gonorrhoeae; Pregnancy; Prevalence; Risk factors