Primary thyroid lymphoma: A rare disease.
Primary thyroid lymphomas are rare neoplasms comprising of 1-5% of thyroid malignancies. These are predominantly B-cell in origin. Here, we report a case of 60 years lady, a known case of lymphocytic thyroiditis, diagnosed as thyroid lymphoma (diffuse large B-cell) on fine needle aspiration and confirmed histopathogically and immunohistochemically. She presented with a sudden increase in thyroid swelling. Fine needle aspiration performed showed highly cellular smears comprising predominantly of the monomorphic population of medium to large sized lymphoid cells with high nuclear/cytoplasmic ratio and scant cytoplasm. A possibility of thyroid lymphoma possibly diffuse large B-cell lymphoma was suggested which was later confirmed on biopsy. Fine needle aspiration provides an easy mode for diagnosing large cell lymphoma like diffuse large B-cell. Hence, an early diagnosis is possible for a timely intervention. Also, cases of lymphocytic thyroiditis should be regularly followed for the development of lymphoma.
Department of Pathology, Lady Hardinge Medical College and Shrimati Sucheta Kriplani Hospital, New Delhi, India.
Deepti
D
Verma
Department of Pathology, Lady Hardinge Medical College and Shrimati Sucheta Kriplani Hospital, New Delhi, India.
Vandana
V
Puri
Department of Pathology, Lady Hardinge Medical College and Shrimati Sucheta Kriplani Hospital, New Delhi, India.
Shilpi
S
Agarwal
Department of Pathology, Lady Hardinge Medical College and Shrimati Sucheta Kriplani Hospital, New Delhi, India.
Aasha
A
Bhaskar
Lymphoma; fine needle aspiration cytology; primary; thyroid; thyroiditis