[A case of long-term survival in a patient with rectal cancer with virchow lymph node metastasis, liver metastases, and lung metastases].
A 69-year-old man with advanced rectal cancer and liver metastases was treated with 2 courses of chemotherapy with irinotecan and S-1 followed by low anterior resection and partial hepatectomy. Chemotherapy with S-1 was then administered for 22 months. However, lung metastases developed, for which partial pneumonectomy was performed. Seven months later, computed tomography (CT) revealed swelling of the left supraclavicular lymph node. Despite chemotherapy with 5- fluorouracil, Leucovorin, and oxaliplatin (mFOLFOX6); 5-fluorouracil, Leucovorin and irinotecan (FOLFIRI); and capecitabine plus bevacizumab, the lung metastases recurred and Virchow lymph node swelling was noted again. Accordingly, palliative therapy was administered. The patient died 3 years 1 month after Virchow lymph node resection. Herein, we describe a case of advanced rectal cancer, in which lung and Virchow lymph node metastases developed after liver metastasis. Surgical excision of the metastases resulted in long-term survival of 6 years following the first operation.
Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences.
Hidehito
H
Oyanagi
Hitoshi
H
Kameyama
Hitoshi
H
Nogami
Yoshifumi
Y
Shimada
Mae
M
Nakano
Masato
M
Nakano
Takashi
T
Ishikawa
Jun
J
Sakata
Takashi
T
Kobayashi
Masahiro
M
Minagawa
Shinichi
S
Kosugi
Yu
Y
Koyama
Toshifumi
T
Wakai
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017809:Fatal Outcome; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D012004:Rectal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D013997:Time Factors