The effect of transcranial direct current stimulation on task processing and prioritisation during dual-task gait.
The relationship between cognition and gait is often explored using a dual-task gait paradigm, which represents the ability to divide cognitive resources during walking. Recent evidence has suggested that the prefrontal cortex is involved in the allocation of cognitive resources during dual-task gait, though its precise role is unclear. Here, we used anodal and cathodal transcranial direct current stimulation (tDCS) to probe the role of the prefrontal cortex in the control of stride time variability (STV), trunk RoM and cognitive task performance during dual-task gait. As task difficulty has been shown to mediate the dual-task cost, we also manipulated walking speed to see whether the effects of tDCS on dual-task gait were influenced by walking difficulty. Ten adults performed a serial subtraction task when walking at either preferred walking speed or 25 % of preferred walking speed, before and after receiving tDCS of the left prefrontal cortex. Anodal tDCS reduced STV and the dual-task cost on STV and improved cognitive task performance. Cathodal tDCS increased STV and appeared to increase the dual-task cost on STV, but did not affect cognitive task performance. There was no effect of tDCS on trunk RoM, and the effects of tDCS were not mediated by walking speed. The effect of dual-task gait on stride time variability and cognitive task performance was altered by the application of tDCS, and these effects were polarity dependent. These results highlight the role of the prefrontal cortex in biasing task performance during dual-task gait and indicate that tDCS may be a useful tool for examining the role of the cortex in the control of dual-task gait.
The Centre for Sport and Exercise Science and Medicine (SESAME), University of Brighton, Eastbourne, East Sussex, UK, J.Wrightson2@Brighton.ac.uk.
James G
JG
Wrightson
Rosie
R
Twomey
Emma Z
EZ
Ross
Nicholas J
NJ
Smeeton
D000328:Adult; D003071:Cognition / Q000502:physiology*; D004566:Electrodes; D005260:Female; D007839:Functional Laterality; D005684:Gait / Q000502:physiology*; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D017397:Prefrontal Cortex / Q000502:physiology*; D011597:Psychomotor Performance; D011930:Reaction Time; D013997:Time Factors; D065908:Transcranial Direct Current Stimulation; D055815:Young Adult