[Forensic application of 30 InDel loci in Han and She nationalities of Eastern China].
OBJECTIVE
To evaluate the forensic application value of 30 insertion/deletion (InDel) loci included in Investigator DIPplex Kit in Han and She nationalities of Eastern China.


METHODS
A total of 565 unrelated individuals in Han nationality and 119 ones in She nationality of Eastern China were investigated using Investigator DIPplex Kit. Allele frequencies, population genetics parameters of the 30 InDel loci were statistically calculated.


RESULTS
In Han nationality, the mean Ho was 0.413 3, the mean DP was 0.551 1, the mean PIC was 0.320 0. And in She nationality, the mean Ho was 0.389 6, the mean DP was 0.543 3, the mean PIC was 0.310 0. No deviation from Hardy-Weinberg equilibrium was observed in Han and She nationalities (P > 0.05).


CONCLUSIONS
The 30 loci in Investigator DIPplex Kit show good genetic diversity in Han and She nationalities, and could be used as a supplemental tool for some special paternity cases.
Zhen
Z
Hu
Zheng
Z
Wang
Su-hua
SH
Zhang
Shu-min
SM
Zhao
Ru-xin
RX
Zhu
Kuan
K
Sun
Cheng-tao
CT
Li
D044466:Asian People / Q000235:genetics*; D002681:China; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D053803:Forensic Genetics; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D006801:Humans; D054643:INDEL Mutation / Q000235:genetics*; D011110:Polymorphism, Genetic