The synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma and arteriovenous malformations.
BACKGROUND
Hemangioma is the most common tumor of neonatal period and it is almost always appeared by the end of the first week of life and can be found mostly in head and neck area. This study evaluated the synergistic effect of bleomycin, triamcinolone and epinephrine in treatment of hemangioma and arteriovenous malformations.


METHODS
In this multicenter study, a combination of bleomycin, triamcinolone and epinephrine was injected intralesionaly for treatment of hemangiomas and arteriovenous malformations and their synergistic effect was evaluated in 32 patients.


RESULTS
Hemangiomas and low-flow arteriovenous malformations were treated well with their combination while port-wine spots and high-flow lesions response were relatively poor.


CONCLUSIONS
It seems that the combination of bleomycin, triamcinolone and epinephrine may be a good choice in treatment of hemangioma and arteriovenous malformations.
Private practis Metairie, LA, USA.
Hamid
H
Masiha
Department of Plastic Surgery, Shiraz University of Medical Sciences Shiraz, Iran.
Heydar Ali
HA
Nikpour
Department of Plastic Surgery, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Esmaeil
ME
Hasani
Department of Plastic Surgery, Tehran University of Medical Sciences, Tehran, Iran.
Abolhasan
A
Emami
Medical Student, Tehran University of Medical Sciences, Tehran, Iran.
Mehryar
M
Jafari
Department of Plastic Surgery, Tehran University of Medical Sciences, Tehran, Iran.
Ali
A
Manafi
Arteriovenous malformation; Bleomycin; Epinephrine; Hemangioma; Triamcinolone