[Clinical significance of ascites on preoperative MDCT in patients with advanced gastric cancer].
In advanced gastric cancer patients, preoperative multi detector row computed tomography (MDCT) often reveals abnormal ascites, which can indicate the possibility of peritoneal metastasis. The aim of this study was to clarify the clinical significance of preoperative ascites revealed by MDCT in gastric cancer patients. The study included a total of 183 advanced gastric cancer patients who underwent consecutive surgical procedures from February 2008 to November 2011. The results indicate that the presence of ascites on MDCT is significantly correlated with peritoneal metastasis (p<.005), pathological T4 (p< 0.005), R1-R2 (p<.01), and a positive diagnosis of peritoneal washing cytology(p<.05). Multivariate analysis indicated that the presence of ascites on MDCT was an independent prognostic factor (hazard ratio[HR]2.6). In conclusion, the presence of ascites on preoperative MDCT is strongly associated with peritoneal metastasis, and might indicate the need for diagnostic laparoscopy to evaluate Stage IV factors and select the best treatment strategy.
Dept. of Surgery, Division of Digestive Surgery, Kyoto Prefectural University of Medicine.
Hisataka
H
Matsuo
Shuhei
S
Komatsu
Daisuke
D
Ichikawa
Takeshi
T
Kubota
Kazuma
K
Okamoto
Hirotaka
H
Konishi
Atsushi
A
Shiozaki
Hitoshi
H
Fujiwara
Ryo
R
Morimura
Yasutoshi
Y
Murayama
Yoshiaki
Y
Kuriu
Hisashi
H
Ikoma
Masayoshi
M
Nakanishi
Chouhei
C
Sakakura
Eigo
E
Otsuji
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001201:Ascites / Q000000981:diagnostic imaging* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010534:Peritoneal Neoplasms / Q000556:secondary; D011379:Prognosis; D013274:Stomach Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed