Treatment of distant metastases from follicular cell-derived thyroid cancer.
Distant metastases from thyroid cancer of follicular origin are uncommon. Treatment includes levothyroxine administration at suppressive doses, focal treatment modalities with surgery, external radiation therapy and thermal ablation, and radioiodine in patients with uptake of (131)I in their metastases. Two thirds of distant metastases will become refractory to radioiodine at some point, and when there is a significant tumor burden and documented progression on imaging, a treatment with a kinase inhibitor may provide benefits.
Department of Nuclear Medicine and Endocrine Oncology, and TUTHYREF (Tumeurs de la Thyroïde Réfractaires) network, Gustave Roussy and University Paris-Sud 114 rue Edouard Vaillant, 94800 Villejuif France.
Martin
M
Schlumberger
Department of Nuclear Medicine and Endocrine Oncology, and TUTHYREF (Tumeurs de la Thyroïde Réfractaires) network, Gustave Roussy and University Paris-Sud 114 rue Edouard Vaillant, 94800 Villejuif France.
Sophie
S
Leboulleux