[Effect of space flight factors simulated in ground-based experiments on the behavior, discriminant learning, and exchange of monoamines in different brain structures of rats].
Experimental treatment (long-term fractionated γ-irradiation, antiorthostatic hypodynamia, and the combination of these factors) simulating the effect of space flight in ground-based experiments rapidly restored the motor and orienting-investigative activity of animals (rats) in "open-field" tests. The study of the dynamics of discriminant learning of rats of experimental groups did not show significant differences from the control animals. It was found that the minor effect of these factors on the cognitive performance of animals correlated with slight changes in the concentration ofmonoamines in the brain structures responsible for the cognitive, emotional, and motivational functions.
A S
AS
Shtemberg
K V
KV
Lebedeva-Georgievskaia
M I
MI
Matveeva
V S
VS
Kudrin
V B
VB
Narkevich
P M
PM
Klodt
A S
AS
Bazian
D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000528:radiation effects; D002395:Catecholamines / Q000378:metabolism* / Q000528:radiation effects; D003071:Cognition / Q000502:physiology* / Q000528:radiation effects; D005720:Gamma Rays; D018476:Hypokinesia; D007858:Learning / Q000502:physiology / Q000528:radiation effects; D008297:Male; D051381:Rats; D013026:Space Flight
D002395:Catecholamines