[An examination of the utility of high-precise radiation therapies for the recurrence of postoperative esophageal cancer].
We analyzed 16 cases (23 therapeutic sites) of post-operative recurrence of esophageal cancers that were treated with high-precise radiation therapies.The recurrence sites were cervical lymph nodes (5 cases), superior mediastinal lymph nodes (5 cases), posterior mediastinal lymph nodes (3 cases), regional lymph nodes with anastomosis (2 cases), abdominal paraaortic lymph node (3 cases), and regions with hematogenous metastasis (5 cases: liver, lung, spleen, and dissemination to the diaphragm bottom).By recurrence number, 10 cases presented with a single lesion, and 6 cases had multiple lesions.The effect of the treatment was complete response (CR) in all cases, and 6 cases maintained CR.The median of the overall survival after radiotherapy was 562 (132-1,231) days.Analysis of the prognostic factors for the overall survival from a recurrence revealed that the metastatic number (single) (p=0.003), and the metastatic pattern(hematogenous metastasis) (p= 0.004), significantly improved prognosis.We conclude that radiotherapy is an option to extend prognosis in some recurrence cases.
Dept. of Surgery, Hiroshima City Hiroshima Citizens Hospital.
Takuya
T
Kato
Masao
M
Harano
Hitoshi
H
Idani
Yasuhiro
Y
Choda
Noriaki
N
Tokumoto
Takashi
T
Kanazawa
Hiroyoshi
H
Matsukawa
Yasutomo
Y
Ojima
Shigehiro
S
Shiozaki
Masazumi
M
Okajima
Motoki
M
Ninomiya
Kanji
K
Matsuura
Yutaka
Y
Hirokawa
Satoshi
S
Ohno
D000368:Aged; D004938:Esophageal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D016629:Esophagectomy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D016896:Treatment Outcome