14-year-old boy with painful nail changes.
Doxycycline is a classically implicated cause of phototoxic reactions. Photo-onycholysis is a rare manifestation of phototoxicity. Nail changes may typically include nail pain, subungual hemorrhages, or distal onycholysis. Self-resolution can be expected in 3 to 6 months. Patients prescribed doxycycline should be counseled about the potential for phototoxicity and the need for appropriate sun protection while taking the medication.
Pediatric Medicine Division, Sick Kids Hospital, Toronto, Ontario, Canada.
Shudeshna
S
Nag
Pediatric Medicine Division, Sick Kids Hospital, Toronto, Ontario, Canada.
Miriam
M
Weinstein
Pediatric Medicine Division, Sick Kids Hospital, Toronto, Ontario, Canada.
Saul
S
Greenberg
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D017454:Dermatitis, Photoallergic / Q000175:diagnosis / Q000209:etiology; D004318:Doxycycline / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009262:Nails / Q000503:physiopathology; D054039:Onycholysis / Q000139:chemically induced* / Q000175:diagnosis* / Q000503:physiopathology; D010146:Pain / Q000175:diagnosis / Q000209:etiology
D000900:Anti-Bacterial Agents; D004318:Doxycycline