Development and evaluation of a latex agglutination test for the rapid serodiagnosis of tularemia.
A latex agglutination test (LAT) was developed for a rapid detection of antibodies against Francisella tularensis. The assay is performed by mixing serum with antigen-coated latex beads and read within 5 min. Developed LAT has been proved to be a specific, sensitive, fast, easy-to-perform and cost-efficient tool for the routine diagnosis of tularemia.
Department of Bacteriology, National Institute of Public Health-National Institute of Hygiene, Warsaw, Poland. Electronic address: wrastawicki@pzh.gov.pl.
Waldemar
W
Rastawicki
Department of Bacteriology, National Institute of Public Health-National Institute of Hygiene, Warsaw, Poland.
Natalia
N
Rokosz-Chudziak
Department of Bacteriology, National Institute of Public Health-National Institute of Hygiene, Warsaw, Poland.
Anna
A
Chróst
Department of Bacteriology, National Institute of Public Health-National Institute of Hygiene, Warsaw, Poland.
Rafał
R
Gierczyński
D000907:Antibodies, Bacterial / Q000097:blood*; D003365:Costs and Cost Analysis; D005604:Francisella tularensis / Q000276:immunology*; D006801:Humans; D007841:Latex Fixation Tests / Q000191:economics / Q000379:methods*; D012680:Sensitivity and Specificity; D012698:Serologic Tests / Q000191:economics / Q000379:methods; D014406:Tularemia / Q000175:diagnosis*
D000907:Antibodies, Bacterial
F. tularensis; Latex agglutination test; Serodiagnosis; Tularemia