Synthesis and indole coupling reactions of azetidine and oxetane sulfinate salts.
Azetidine and oxetane sulfinate salts are easily prepared from commercially available 3-iodoheterocycle precursors in a three-step sequence. They undergo smooth coupling reactions thereby providing an expedient route for the introduction of these four-membered heterocycles into indoles.
Department of Chemistry, University of Sheffield, Brook Hill, Sheffield, S3 7HF, UK. j.harrity@sheffield.ac.uk.
Anne-Chloé M A
AC
Nassoy
Piotr
P
Raubo
Joseph P A
JP
Harrity
D001384:Azetidines / Q000138:chemical synthesis*; D004988:Ethers, Cyclic / Q000138:chemical synthesis*; D007211:Indoles / Q000737:chemistry*; D010084:Oxidation-Reduction; D012492:Salts; D013441:Sulfinic Acids / Q000737:chemistry*
D001384:Azetidines; D004988:Ethers, Cyclic; D007211:Indoles; D012492:Salts; D013441:Sulfinic Acids; C082735:azetidine; C005287:oxetane