[Postoperative cognitive dysfunction after non-cardiac surgery].
Postoperative cognitive dysfunction (POCD) is seen not only after cardiac surgery but also after non-cardiac surgery. POCD leads to decreased quality of life and increased mortality. Various reports describe the occurrence and risk factor of POCD in adopting different neuropsychological tests and different follow-up periods. POCD is highly associated with age or inflammation in the central nerve system. Anti-inflammatory strategies including dexmedetomidine, statin or minocycline in the perioperative period may reduce incidence of POCD.
Mitsuru
M
Ida
Masahiko
M
Kawaguchi
D000768:Anesthesia, General / Q000009:adverse effects; D006348:Cardiac Surgical Procedures; D003072:Cognition Disorders / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control / Q000628:therapy; D006801:Humans; D011183:Postoperative Complications; D012307:Risk Factors