Inflammation. Potent small molecule extinguishes the NLRP3 inflammasome.
Sarah
S
Onuora
D000818:Animals; D002352:Carrier Proteins / Q000037:antagonists & inhibitors*; D056587:Cryopyrin-Associated Periodic Syndromes / Q000188:drug therapy*; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000188:drug therapy*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000627:therapeutic use*; D006801:Humans; D058847:Inflammasomes / Q000037:antagonists & inhibitors*; D053583:Interleukin-1beta / Q000187:drug effects*; D009103:Multiple Sclerosis; D013450:Sulfones / Q000627:therapeutic use*
D002352:Carrier Proteins; D006576:Heterocyclic Compounds, 4 or More Rings; D058847:Inflammasomes; D053583:Interleukin-1beta; D013450:Sulfones