[Certain opioids can preferably be administered transdermally].
Many patients experience acute or chronic pain. The options for treating these pain conditions are many, and particularly products for topical application are gaining ground. NSAID for topical use is a good alternative to NSAID administered orally due to less systemic side effects. Transdermally delivered opioids have proven to be as effective as morphine in pain management of chronic, moderate to severe pain. The steady delivery and lower risk of breakthrough pain overweigh the higher cost and risk of adverse events compared to the orally delivered opioids.
Plastikkirurgisk Afdeling Z, Odense Universitetshospital, Sdr. Boulevard 29, 5000 Odense. nmjensen@health.sdu.dk.
Niels Martin
NM
Jensen
Rikke
R
Holmgaard
Jesper Bo
JB
Nielsen
Jens Ahm
JA
Sørensen
D059787:Acute Pain / Q000188:drug therapy; D000279:Administration, Cutaneous; D000284:Administration, Oral; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D059350:Chronic Pain / Q000188:drug therapy; D003718:Denmark; D006801:Humans; D057968:Transdermal Patch
D000701:Analgesics, Opioid; D000894:Anti-Inflammatory Agents, Non-Steroidal