Advanced thymic cancer treated with carboplatin and paclitaxel in a patient undergoing hemodialysis.
A 53-year-old man with an asymptomatic anterior mediastinal tumor undergoing hemodialysis was referred to our institution. He was diagnosed with thymic basaloid carcinoma based on the findings of a chest tomography-guided biopsy and successfully treated with carboplatin (300 mg/m(2)/day) and paclitaxel (200 mg/m(2)/day) on day 1 for six three-week cycles. To our knowledge, this is the first report regarding the efficiency of a carboplatin dose-definition method based on the body surface area with paclitaxel in a hemodialysis patient. This report may therefore be useful for treating hemodialysis patients who are candidates for carboplatin and paclitaxel therapy.
Department of Medicine (II), Niigata University Medical and Dental Hospital, Japan.
Satoru
S
Miura
Hiroshi
H
Kagamu
Takehito
T
Sakai
Koichiro
K
Nozaki
Katsuaki
K
Asakawa
Hiroshi
H
Moro
Masaaki
M
Okajima
Satoshi
S
Watanabe
Suguru
S
Yamamoto
Noriaki
N
Iino
Shin
S
Goto
Junichiro James
JJ
Kazama
Hirohisa
H
Yoshizawa
Ichiei
I
Narita
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage*; D006435:Renal Dialysis; D013945:Thymoma / Q000188:drug therapy*; D013953:Thymus Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
D016190:Carboplatin; D017239:Paclitaxel