Prophylactic antibiotics in dermatological surgery.
This is a review of the common pathogens of surgical site infections, antibiotic coverage for particular anatomical sites, mechanisms by which surgical site infections occur and the latest data and recommendations for prophylactic antibiotics in the prevention of surgical site infections, infective endocarditis and haematogenous joint infections. Recent evidence-based guidelines on surgical prophylaxis is for restricted indications and a shorter duration of antibiotic prophylaxis in situations where no clinical benefit of prolonged therapy has been proven, in order to minimise the potential adverse ecological and clinical effects associated with antibiotic therapy. This review recommends the cautious use of prophylactic antibiotics in dermatological surgery to help prevent the growing problem of bacterial resistance as well as other morbidity and health-care costs.
Skin and Cancer Foundation, Sydney, New South Wales, Australia.
Michael R
MR
Lee
Skin and Cancer Foundation, Sydney, New South Wales, Australia.
Robert
R
Paver
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000009:adverse effects; D062109:Dermatologic Surgical Procedures / Q000009:adverse effects*; D004696:Endocarditis / Q000517:prevention & control; D006801:Humans; D007592:Joint Diseases / Q000382:microbiology / Q000517:prevention & control; D011552:Pseudomonas Infections / Q000382:microbiology / Q000517:prevention & control; D012307:Risk Factors; D013207:Staphylococcal Skin Infections / Q000382:microbiology / Q000517:prevention & control*; D013290:Streptococcal Infections / Q000382:microbiology / Q000517:prevention & control; D013530:Surgical Wound Infection / Q000382:microbiology / Q000517:prevention & control*
D000900:Anti-Bacterial Agents