Computerized PET/CT image analysis in the evaluation of tumour response to therapy.
Current cancer therapy strategy is mostly population based, however, there are large differences in tumour response among patients. It is therefore important for treating physicians to know individual tumour response. In recent years, many studies proposed the use of computerized positron emission tomography/CT image analysis in the evaluation of tumour response. Results showed that computerized analysis overcame some major limitations of current qualitative and semiquantitative analysis and led to improved accuracy. In this review, we summarize these studies in four steps of the analysis: image registration, tumour segmentation, image feature extraction and response evaluation. Future works are proposed and challenges described.
Department of Radiation Oncology, University of Maryland, School of Medicine, Baltimore, MD, USA.
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D000465:Algorithms; D003287:Contrast Media; D006801:Humans; D064847:Multimodal Imaging; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D049268:Positron-Emission Tomography; D011857:Radiographic Image Interpretation, Computer-Assisted; D019275:Radiopharmaceuticals; D060388:Support Vector Machine; D014057:Tomography, X-Ray Computed
D003287:Contrast Media; D019275:Radiopharmaceuticals