Structural and ultrastructural study of rat liver influenced by electromagnetic radiation.
Mobile communication systems are undoubtedly an environmental source of electromagnetic radiation (EMR). There is an increasing concern regarding the interactions of EMR with the humans. The aim of this study was to examine the effects of EMR on Wistar rat liver. Mature rats were exposed to electromagnetic field of frequency 2.45 GHz and mean power density of 2.8 mW/cm2 for 3 h/d for 3 wk. Samples of the liver were obtained 3 h after the last irradiation and processed histologically for light and transmission electron microscopy. Data demonstrated the presence of moderate hyperemia, dilatation of liver sinusoids, and small inflammatory foci in the center of liver lobules. Structure of hepatocytes was not altered and all described changes were classified as moderate. Electron microscopy of hepatocytes revealed vesicles of different sizes and shapes, lipid droplets, and proliferation of smooth endoplasmic reticulum. Occasionally necrotizing hepatocytes were observed. Our observations demonstrate that EMR exposure produced adverse effects on rat liver.
a Department of Anatomy, Histology and Physiology , University of Veterinary Medicine and Pharmacy , Košice , Slovak Republic.
K
K
Holovská
V
V
Almášiová
V
V
Cigánková
K
K
Beňová
E
E
Račeková
M
M
Martončíková
D000818:Animals; D060733:Electromagnetic Radiation; D022781:Hepatocytes / Q000528:radiation effects* / Q000648:ultrastructure; D008099:Liver / Q000033:anatomy & histology / Q000528:radiation effects* / Q000648:ultrastructure; D008297:Male; D046529:Microscopy, Electron, Transmission; D051381:Rats; D017208:Rats, Wistar