Biostructural Science Inspired by Next-Generation X-Ray Sources.
Next-generation synchrotron radiation sources, such as X-ray free-electron lasers, energy recovery linacs, and ultra-low-emittance storage rings, are catalyzing novel methods of biomolecular microcrystallography and solution scattering. These methods are described and future trends are predicted. Importantly, there is a growing realization that serial microcrystallography and certain cutting-edge solution scattering experiments can be performed at existing storage ring sources by utilizing new technology. In this sense, next-generation sources are serving two distinct functions, namely, provision of new capabilities that require the newer sources and inspiration of new methods that can be performed at existing sources.
Department of Physics.
Sol M
SM
Gruner
Eaton E
EE
Lattman
D003461:Crystallography / Q000379:methods; D018360:Crystallography, X-Ray / Q000295:instrumentation* / Q000379:methods* / Q000639:trends; D011506:Proteins / Q000737:chemistry*; D017356:Synchrotrons
D011506:Proteins
X-ray free-electron laser; biomolecular solution scattering; bright storage ring sources; energy recovery linac; microcrystallography; nanocrystallography; synchrotron radiation sources