[Aspects of encephalopathy in oncologic patients after chemotherapy].
OBJECTIVE
To study clinical presentations and neuroimaging results in post chemotherapy encephalopathy.


METHODS
We examined 27 patients with cancer after chemotherapy (n=16) or chemoradiation (n=11).


CONCLUSIONS
All patients complained of memory impairment, sluggish mentality, moderate headache, fatigue, sleep disorder, irritability. Their neurologic status included different organic symptoms. Post chemotherapy encephalopathy is characterized by the combination of severe cerebral asthenia and different organic neurologic symptoms with moderate cephalgic syndrome. MRT showed single and multiple loci of gliosis in the white matter.
FGBU 'Rossiĭskiĭ nauchnyĭ tsentr rentgenoradiologii' Minzdrava Rossii, Moskva.
N B
NB
Kholodova
FGBU 'Rossiĭskiĭ nauchnyĭ tsentr rentgenoradiologii' Minzdrava Rossii, Moskva.
V M
VM
Sotnikov
FGBU 'Rossiĭskiĭ nauchnyĭ tsentr rentgenoradiologii' Minzdrava Rossii, Moskva.
N Iu
NI
Dobrovol'skaia
FGBU 'Rossiĭskiĭ nauchnyĭ tsentr rentgenoradiologii' Minzdrava Rossii, Moskva.
Iu A
IA
Ponkratova
D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001927:Brain Diseases / Q000139:chemically induced* / Q000175:diagnosis* / Q000503:physiopathology; D005221:Fatigue / Q000139:chemically induced / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006261:Headache / Q000139:chemically induced / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy*; D009457:Neuroglia / Q000187:drug effects / Q000473:pathology; D012893:Sleep Wake Disorders / Q000139:chemically induced / Q000175:diagnosis / Q000503:physiopathology
D000970:Antineoplastic Agents