A case of frosted branch angiitis in an immunocompromised child.
Frosted branch angiitis is a rare vascular reaction believed to be a nonspecific immune response to an infective, neoplastic, or idiopathic insult. The clinical presentation is characteristic and typically affects children and younger adults, and the prognosis is good. We report a case of frosted branch angiitis during immune recovery in a 2-year-old boy with Langerhans cell histiocytosis on systemic immunosuppressive therapy.
University of Maryland, Baltimore, Maryland; Children's National Medical Center, Washington, DC. Electronic address: janetleath@gmail.com.
Janet Leath
JL
Alexander
Children's National Medical Center, Washington, DC.
Marijean
M
Miller
D000227:Adenine Nucleotides / Q000627:therapeutic use; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D001087:Arabinonucleosides / Q000627:therapeutic use; D002675:Child, Preschool; D000077866:Clofarabine; D000069585:Filgrastim; D005938:Glucocorticoids / Q000627:therapeutic use; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications / Q000188:drug therapy; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000150:complications / Q000188:drug therapy; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D011994:Recombinant Proteins / Q000627:therapeutic use; D031300:Retinal Vasculitis / Q000175:diagnosis* / Q000188:drug therapy
D000227:Adenine Nucleotides; D000964:Antimetabolites, Antineoplastic; D001087:Arabinonucleosides; D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor; D000077866:Clofarabine; D000069585:Filgrastim; D008775:Methylprednisolone