Cataract surgery in children with congenital keratolenticular adhesion (Peters anomaly type 2).
OBJECTIVE
To report the visual and surgical outcomes after cataract surgery in children with keratolenticular adhesion (Peters anomaly type 2).


METHODS
The medical records of consecutive patients with keratolenticular adhesion (KLA) with partial (iris defects)/complete aniridia were retrospectively reviewed. Cataract surgery (in-the-bag irrigation and aspiration) with or without intraocular lens implantation and with or without broad iridectomy was performed. The main outcome measures were postoperative visual acuity, complications, and progression of corneal opacity.


RESULTS
The study included 4 eyes of 3 patients ranging in age from 3 months to 7 years. The mean age at cataract surgery was 37 months; the median, 24 months (range, 3-84 months). The mean follow-up was 3.3 years and median was 2 years (range, 2-6 years). Preoperative visual acuity ranged from fixing and following objects to 20/200. Only 1 patient had PAX6 mutation-confirmed aniridia. The other 2 patients had partial iris defects. All eyes improved in visual acuity ranging from counting fingers at 3 feet to 20/60. There was no progression of corneal opacity. There were no postoperative complications.


CONCLUSIONS
Children with KLA with complete or partial iris defects with localized corneal opacity and cataract can achieve satisfactory visual outcomes by undergoing meticulous lensectomy with or without iridectomy.
Pediatric Ophthalmology, Strabismus, and Adult Motility, Children's Hospital of Pittsburgh of UPMC, UPMC Eye Center, Pittsburgh, Pennsylvania.
Anagha
A
Medsinge
Pediatric Ophthalmology, Strabismus, and Adult Motility, Children's Hospital of Pittsburgh of UPMC, UPMC Eye Center, Pittsburgh, Pennsylvania; Great Ormond Street Hospital for Children, London, United Kingdom; University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Electronic address: nischalkk@upmc.edu.
Ken K
KK
Nischal
D000869:Anterior Eye Segment / Q000002:abnormalities* / Q000503:physiopathology / Q000601:surgery; D002387:Cataract Extraction; D002648:Child; D002675:Child, Preschool; D003318:Corneal Opacity / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D005124:Eye Abnormalities / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D032801:Iridectomy; D019654:Lens Implantation, Intraocular; D008297:Male; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology