[Serum vitamin D and metabolic risk factors in a group of Spanish schoolchildren].
OBJECTIVE
To analyze the vitamin D status and its relationship with metabolic syndrome (MS) risk factors in a group of Spanish schoolchildren.


METHODS
A group of 314 Spanish schoolchildren (8-13 years old) from A Coruna, Barcelona, Madrid, Seville and Valencia were studied. Anthropometric data on weight, height, waist and hip circumferences, and triceps skinfold, as well as blood pressure data were collected. Serum levels of glucose, triglycerides, HDL-c and 25-hydroxycholecalciferol (25 (OH) D) were assessed. Following Cook criterion, the following MS risk factors were defined: glucose ≥100 mg/dL; ≥P90 waist circumference; triglycerides> P90, HDL ≤P10; and sistolic and/or diastolic blood pressure > P90.


RESULTS
Mean serum 25(OH)D were 23.0±8.6 ng/mL. Forty seven percent of children had hypovitaminosis (20- 30 ng/mL) and 35% had vitamin deficiency (<20 ng/mL). Compared to the first tertile, children in the second tertile have a lower risk of elevated triglycerides (OR = 0.50 [CI = 0.25 to 0.99]; those in the the third tertile had lower risk of high blood pressure and triglycerides (0.60 [CI = 0.42-0.86] and 0.50 [CI = 0.32 to 0.79], respectively).


CONCLUSIONS
The prevalence of vitamin D deficiency is high in this group of Spanish schoolchildren. Low serum levels of vitamin D are associated with an increased risk of elevated triglycerides and blood pressure.
Instituto Superior de Investigaciones Biológicas (INSIBIO). Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucumán.. ajdepiero@hotmail.com.
Alexia
A
De Piero Belmonte
Sección Departamental de Química Analítica, Facultad de Farmacia, Universidad Complutense de Madrid, Ciudad Universitaria, Madrid, España. Grupo de Investigación VALORNUT-UCM (920030). Universidad Complutense de Madrid. Madrid. España.. elena-rd79@farm.ucm.es.
Elena
E
Rodríguez-Rodriguez
Grupo de Investigación VALORNUT-UCM (920030). Universidad Complutense de Madrid. Madrid. España. Departamento de Nutrición Humana y Dietética. Facultad de Ciencias de la Salud. Universidad Alfonso X El Sabio. Villanueva de la Cañada. Madrid. España.. liri@hotmail.com.
Liliana Guadalupe
LG
González-Rodríguez
Grupo de Investigación VALORNUT-UCM (920030). Universidad Complutense de Madrid. Madrid. España. Departamento de Nutrición Humana y Dietética. Facultad de Ciencias de la Salud. Universidad Alfonso X El Sabio. Villanueva de la Cañada. Madrid. España.. rortega@ucm.es.
Rosa María
RM
Ortega Anta
Grupo de Investigación VALORNUT-UCM (920030). Universidad Complutense de Madrid. Madrid. España. Departamento de Nutrición, Facultad de Farmacia, Universidad Complutense de Madrid, Ciudad Universitaria. Madrid. España.. asobaler@ucm.es.
Ana María
AM
López-Sobaler
D000293:Adolescent; D000886:Anthropometry; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D002648:Child; D015897:Comorbidity; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000453:epidemiology*; D012307:Risk Factors; D013030:Spain; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000453:epidemiology*
D001786:Blood Glucose; D008055:Lipids; D014807:Vitamin D; C104450:25-hydroxyvitamin D