Adequacy of cervical sampling in hysterectomy specimens for endometrial cancer.
OBJECTIVE
To determine whether sampling one section, which includes the anterior and posterior cervical lips in hysterectomy specimens, provides the best prospect for detecting stromal invasion in hysterectomy specimens for endometrial cancers.


METHODS
To assess the most likely section in which cervical stromal invasion was identified in 29 cases.


RESULTS
Cervical stromal invasion was detected in first section in 75.8% cases, whereas 24.1% detected in random sections other than first section.


CONCLUSIONS
Cervical stromal invasion is most likely to be identified in one section taken in the midline, which includes anterior and posterior lips. However, in a significant number of cases, this one section missed invasion, which was detected in other random cervical sections. Therefore, sampling of one block (anterior and posterior) from the cervix is insufficient for detecting cervical stromal invasion for endometrial cancer.
Department of Pathology Laboratory Medicine/FM Building, Southern General Hospital, Glasgow, UK. Electronic address: sheebamomin@yahoo.com.
Sheeba
S
Syed
Beatson Oncology Centre, Glasgow, UK. Electronic address: Nick.Reed@ggc.scot.nhs.uk.
Nick
N
Reed
Department of Pathology Laboratory Medicine/FM Building, Southern General Hospital, Glasgow, UK. Electronic address: David.Millan@ggc.scot.nhs.uk.
David
D
Millan
D000328:Adult; D002584:Cervix Uteri / Q000473:pathology*; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000601:surgery*; D005260:Female; D005629:Frozen Sections; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D013048:Specimen Handling / Q000379:methods* / Q000592:standards
Cervical sampling; Cervical stromal invasion; Endometrial cancer