Magnetic resonance imaging criteria for thrombolysis in hyperacute cerebral infarction.
OBJECTIVE
Selection of patients with cerebral infarction for MRI that is suitable for thrombolytic therapy as an emerging application. Although the efficiency of the therapy with i.v. tissue plasminogen activator (tPA) within 3 hours after onset of symptoms has been proven in selected patients with CT, now these criteria are determined by MRI, as the data we gather are fast and accurate in the first hours.


METHODS
MRI screening in patients with acute cerebral infarction before application of thrombolytic therapy was done in a UCC Mannheim in Germany. Unlike trials with CT, MRI studies demonstrated the benefits of therapy up to 6 hours after the onset of symptoms. We studied 21 patients hospitalized in Clinic of Neuroradiology at University Clinical Centre in Mannheim-Germany. They all undergo brain MRI evaluation for stroke. This article reviews literature that has followed application of thrombolysis in patients with cerebral infarction based on MRI.


RESULTS
We have analyzed the MRI criteria for i.v. application of tPA at this University Centre. Alongside the personal viewpoints of clinicians, survey reveals a variety of clinical aspects and MRI features that are opened for further more exploration: therapeutic effects, the use of the MRI angiography, dynamics, and other.


CONCLUSIONS
MRI is a tested imaging method for rapid evaluation of patients with hyperacute cerebral infarction, replacing the use of CT imaging and clinical features. MRI criteria for thrombolytic therapy are being applied in some cerebral vascular centres. In Kosovo, the application of thrombolytic therapy has not started yet.
Clinic of Radiology, UCCK, Pristine, Kosova ; Faculty of Medicine, Pristine University, Pristine, Kosova ; Prima Imaging Centre, Pristine, Kosovaa.
Ilir
I
Ahmetgjekaj
Clinic of Radiology, UCCK, Pristine, Kosova ; Faculty of Medicine, Pristine University, Pristine, Kosova ; Prima Imaging Centre, Pristine, Kosovaa.
Serbeze
S
Kabashi-Muçaj
University of Medicine and Pharmacy of Craiova, Romania.
Luana Corina
LC
Lascu
Clinic of Radiology, UCCK, Pristine, Kosova ; Faculty of Medicine, Pristine University, Pristine, Kosova ; Prima Imaging Centre, Pristine, Kosovaa.
Antigona
A
Kabashi
University of Medicine and Pharmacy of Craiova, Romania.
A
A
Bondari
University of Medicine and Pharmacy of Craiova, Romania.
Simona
S
Bondari
Clinic of Radiology, UCCK, Pristine, Kosova ; Faculty of Medicine, Pristine University, Pristine, Kosova.
Kreshnike
K
Dedushi-Hoti
Clinic of Radiology, UCCK, Pristine, Kosova ; Faculty of Medicine, Pristine University, Pristine, Kosova.
Ardian
A
Biçaku
Clinic of Radiology, UCCK, Pristine, Kosova ; Faculty of Medicine, Pristine University, Pristine, Kosova.
Jeton
J
Shatri
MRI; cerebral infarctions; diffusion; perfusion; thrombolysis