An OXA-48-producing Escherichia coli isolated from a Danish patient with no hospitalization abroad.
Carbapenemase-producing organisms are disseminating globally and are now emerging as a worrying threat in Scandinavia. Before August 2013, OXA-48-producing organisms had not been detected in Danish patients. Here we report the isolation of an ST746 OXA-48-producing Escherichia coli with the plasmid pOXA-48a carrying the blaOXA-48 gene isolated from a Danish patient without history of hospitalization abroad. The patient reported tourist travel to Egypt and Turkey. The potential acquisition of carbapenemase-producing organisms by ingestion of contaminated food is discussed.
From the 1 Department of Clinical Microbiology, Aarhus University Hospital , Aarhus.
Anne
A
Gedebjerg
Henrik
H
Hasman
Christian Møller
CM
Sørensen
Mikala
M
Wang
D003718:Denmark; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004534:Egypt; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins / Q000096:biosynthesis*; D005260:Female; D016680:Genome, Bacterial; D006760:Hospitalization; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010957:Plasmids; D017422:Sequence Analysis, DNA; D014195:Travel; D014421:Turkey; D001618:beta-Lactamases / Q000096:biosynthesis*
D029968:Escherichia coli Proteins; D001618:beta-Lactamases; C000601047:beta-lactamase OXA-48, E coli
Enterobacteriaceae; OXA-48; Travel-associated spread; carbapenem resistance