Effects of conservative laparoscopic endometrial cystectomy and use of kidney-reinforcing and blood activating traditional Chinese medicine on ovarian functions.
This study investigated functional changes in the ovaries of women who have had conservative laparoscopic endometrial cystectomy and the effects of traditional kidney-reinforcing and blood-activating Traditional Chinese Medicine (TCM) on ovarian function. Seventy female patients who underwent laparoscopic endometrial cystectomy were randomized into two groups: TCM group receiving kidney-reinforcing and blood-activating Chinese medicine (N = 35) and control group receiving only routine follow-up (N = 35). The serum levels of all study participants were measured for follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2) and inhibin B (INHB) prior to and after endometrial surgery. Postoperative menstruation conditions were also assessed. Compared to preoperative conditions, both LH and FSH levels during the postoperative 1st month increased in both groups, while E2 and INHB levels decreased (P < 0.05). In the TCM group, in contrast to the control group and the postoperative 1st month, we observed a decrease in LH and FSH levels during the postoperative 4th month, while E2 and INHB levels increased (P < 0.05). In this study, we found that certain TCM prescriptions lowered postoperative serum FSH and LH levels and increased the serum INHB and basal E2 levels, thereby improving the ovarian reserve.
Department of Gynecology, Wuhan City Hospital of Tradiocional Chinese Medicine, Wuhan, Hubei, China.
Y H
YH
Huang
Department of Traditional Chinese Medicine, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China linshencn@126.com.
L
L
Shen
Department of Gastroenterology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China.
A H
AH
Cai
Department of Gynecology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China.
X F
XF
Liang
D000328:Adult; D015653:Cystectomy; D004717:Endometrium / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006728:Hormones / Q000097:blood; D006801:Humans; D028322:Inhibin-beta Subunits / Q000097:blood; D007668:Kidney / Q000503:physiopathology*; D010535:Laparoscopy; D008516:Medicine, Chinese Traditional; D008598:Menstruation; D008875:Middle Aged; D010053:Ovary / Q000503:physiopathology*; D055815:Young Adult
D006728:Hormones; C422402:INHBB protein, human; D028322:Inhibin-beta Subunits