A polar-embedded C30 stationary phase: preparation and evaluation.
A novel polar-embedded C30 stationary phase has been synthesized and characterized. The polar carbamate group was generated homogeneously in situ by the catalytic reaction between isocyanate and primary alcohol. The simple one-pot synthetic strategy provided an efficient and effective strategy for modification of silica spheres. Efficiency, selectivity and silanol activity of the resulting column were characterized in detail with different classes of analytes that included Standard Reference Materials (SRM) 870, SRM 869b and SRM 1647e, alkylbenzene congeners, as well as polar-substituted aromatics. The polar-embedded C30 stationary phase was found to exhibit excellent shape selectivity.
Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100049, China.
Mingliang
M
Zhang
School of Chemistry and Chemical Engineering, Henan University of Technology, Zhengzhou 450001, China.
Wenpeng
W
Mai
Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Liang
L
Zhao
Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
Yong
Y
Guo
Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China. Electronic address: hdqiu@licp.cas.cn.
Hongdeng
H
Qiu
D002219:Carbamates / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D057927:Hydrophobic and Hydrophilic Interactions; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis*; D012015:Reference Standards; D012822:Silicon Dioxide / Q000737:chemistry*
D002219:Carbamates; D011084:Polycyclic Aromatic Hydrocarbons; D012822:Silicon Dioxide
Carbamate; Polar-embedded; Reversed-phase liquid chromatography; Shape selectivity; Triacontyl chain