Undiagnosed congenital hypothyroidism in a newborn treated with dopamine infusion.
Medications administered during the neonatal period may mask the diagnosis of congenital hypothyroidism. Herein, we report a case of undiagnosed congenital hypothyroidism while the infant was on treatment with dopamine. Given the inhibitory effect of dopamine on thyroid-stimulating hormone, a high index of suspicion for potential congenital hypothyroidism is needed in such neonates.
Department of Clinical Genetics, Shaan Xi Maternity and Child Health Care Hospital, Xi'an, Shaan Xi 710003, China sxx3690@163.com.
Xuanxing
X
Shi
Department of Clinical Genetics, Shaan Xi Maternity and Child Health Care Hospital, Xi'an, Shaan Xi 710003, China.
Yueling
Y
Sun
Department of Clinical Genetics, Shaan Xi Maternity and Child Health Care Hospital, Xi'an, Shaan Xi 710003, China.
Rong
R
Qiang
D002316:Cardiotonic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002675:Child, Preschool; D003409:Congenital Hypothyroidism / Q000139:chemically induced* / Q000175:diagnosis; D004280:Dobutamine / Q000008:administration & dosage* / Q000009:adverse effects; D004298:Dopamine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D008471:Meconium Aspiration Syndrome / Q000175:diagnosis / Q000188:drug therapy*; D015997:Neonatal Screening; D013972:Thyrotropin / Q000187:drug effects; D016896:Treatment Outcome
D002316:Cardiotonic Agents; D004280:Dobutamine; D013972:Thyrotropin; D004298:Dopamine
congenital hypothyroidism (CH); dopamine treatment; newborn screening (NS); thyroid-stimulating hormone (TSH)