The hunger games.
Although AgRP and POMC neurons in the hypothalamus have long been associated with regulation of food intake, in this issue of Cell, Chen et al. use direct imaging in vivo to demonstrate rapid changes in their activity upon food presentation. The rapidity of their altered responses challenges classic notions of their functions and raises new hypotheses.
Department of Surgery, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: seeleyrj@med.umich.edu.
Randy J
RJ
Seeley
Department of Psychology, University of Michigan, Ann Arbor, MI 48109, USA.
Kent C
KC
Berridge
D000818:Animals; D005247:Feeding Behavior; D009434:Neural Pathways; D009474:Neurons / Q000378:metabolism*