Panniculitis with crystals induced by etanercept subcutaneous injection.
Panniculitis with lipid crystallization within adipocytes may be seen in several disorders, including crystal-storing histiocytosis, gouty panniculitis, subcutaneous fat necrosis of the newborn, post-steroid panniculitis, sclerema neonatorum, oxalosis and subcutaneous fungal infections by mucormycosis, zygomycosis or aspergillosis. Panniculitis at the sites of subcutaneous injection of drugs are frequent, but to our knowledge no crystals have been described in the drug-induced panniculitis at the sites of subcutaneous injections. We report on a patient who developed a panniculitis with lipid crystallization at the site of etanercept injection.
Department of Dermatology, Hospital Universitario La Princesa, Universidad Autónoma, Madrid, Spain.
Mar
M
Llamas-Velasco
Department of Dermatology, Fundación Jiménez Diaz, Universidad Autónoma, Madrid, Spain.
Luis
L
Requena
D017667:Adipocytes / Q000473:pathology; D001706:Biopsy; D000068800:Etanercept / Q000008:administration & dosage* / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D007279:Injections, Subcutaneous; D008875:Middle Aged; D015434:Panniculitis / Q000139:chemically induced* / Q000473:pathology; D011565:Psoriasis / Q000188:drug therapy
D007166:Immunosuppressive Agents; D000068800:Etanercept
adipocytic crystals; etanercept; panniculitis