Diversity of active constituents in Cichorium endivia and Cynara cornigera extracts.
The present study attempts to explore the phytochemical constituents of different extracts from Cynara cornigera and Cichorium endivia plant materials. The two species studied are native in Egypt. Five different solvents, viz., aqueous, methylene chloride, petroleum ether, ethyl acetate, and n-butanol were used. Phytochemical analysis revealed the presence of phenols, flavonoids, sterols (stigmasterol and beta-sitosterol), terpenes (α-amyrin, ursolic and oleanolic acid), and hydrocarbons (n-alkane), the latter found in low amount. The ethyl acetate and water extracts of C. cornigera root showed lower mass fractions of phenolic compounds ranged from 20 to 81 g/100 g, and higher amounts in ethyl acetate extract of the inflorescences and butanol extract of the root where values ranged from 195 to 399 g/100 g. The β-sitosterol and stigmasterol were present in all plant extracts. Oleanolic and ursolic acids were detected in roots, leaves and inflorescences of C. cornigera and in C. endivia shoot. The ethyl acetate extracts from C. cornigera leaf and inflorescence attained higher chemical diversity than the other extracts. Alternatively, sterols and triterpenes were the major constituents. The high chemical diversity of active constituents justifies the future potential use of the two species at commercial level.
King Saud University Department of Botany and Microbiology, College of Science Riyadh 11451 Saudi Arabia Cairo University Department of Botany, Faculty of Science Giza 12613 Egypt.
Ahmad K
AK
Hegazy
Cairo University Department of Pharmacognosy, Faculty of Pharmacy Cairo 11562 Egypt.
Shahira M
SM
Ezzat
Biodiversity and Environmental Research Center (BERC)/ Til POB 696 Nablus West Bank Palestine.
Iman B
IB
Qasem
An-Najah University Department of Biology, Faculty of Science West Bank Palestine.
Mohamed S
MS
Ali-Shtayeh
King Saud University Department of Botany and Microbiology, College of Science Riyadh 11451 Saudi Arabia.
Mohammed O
MO
Basalah
King Saud University Department of Botany and Microbiology, College of Science Riyadh 11451 Saudi Arabia.
Hayssam M
HM
Ali
King Saud University Department of Botany and Microbiology, College of Science Riyadh 11451 Saudi Arabia.
Ashraf A
AA
Hatamleh
D018651:Cichorium intybus / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D031942:Cynara / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology
D010936:Plant Extracts
Egypt; Sterols; flavonoids; phenolic acids; triterpenes