Evidence of unilateral metastatic pulmonary calcification with a prolonged Fever and arthralgia caused by acute lymphoblastic leukemia in a chronic dialysis patient.
A 55-year-old man was transferred to our hospital with unilateral lung lesions, a persistent fever and vague chest pain with arthralgia lasting for three months. He had been treated for end-stage renal disease with hemodialysis for 15 years and had a medical history of recurrent subcutaneous calciphylaxis due to secondary hyperparathyroidism. Transbronchial biopsied specimens demonstrated metastatic pulmonary calcification, and a bone marrow biopsy showed Philadelphia chromosome-positive acute lymphoblastic leukemia. Although metastatic calcification often lacks specific symptoms, the lungs is a primary site for deposition. This is the first report of unilateral metastatic pulmonary calcification associated with secondary hyperparathyroidism.
Department of Respiratory Medicine, Kyorin University School of Medicine, Japan.
Takeshi
T
Saraya
Mitsuru
M
Sada
Kosuke
K
Ohkuma
Sho
S
Sakuma
Naoki
N
Tsujimoto
Shigehiko
S
Yoshida
Masachika
M
Fujiwara
Yayoi
Y
Tsukahara
Daisuke
D
Kurai
Haruyuki
H
Ishii
Hajime
H
Takizawa
Hajime
H
Goto
D018771:Arthralgia / Q000209:etiology; D001706:Biopsy; D002114:Calcinosis / Q000209:etiology* / Q000473:pathology; D005334:Fever / Q000209:etiology; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000473:pathology*; D006435:Renal Dialysis; D016896:Treatment Outcome