Distortion product otoacoustic emission data in perinatally HIV-infected and HIV-exposed but uninfected children and adolescents in the Pediatric HIV/AIDS Cohort Study.
The effect of perinatal HIV infection and exposure on sub-clinical auditory function can be measured with distortion product otoacoustic emissions (DPOAEs). DPOAEs were obtained at 4 frequency bins (1, 2, 3 and 4 kHz) and categorized by a signal-to-noise ratio. HIV infection was not associated with poorer DPOAEs. Among HIV-infected children, HIV viral load≥400 copies/mL had significantly lower odds of better DPOAEs.
From the *School of Speech, Language, and Hearing Sciences, San Diego State University, San Diego, California; †Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, Massachusetts; ‡Epidemiology and Statistics Program, National Institute on Deafness and Other Communication Disorders, National Institutes of Health; and §Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.
Peter
P
Torre
Tzy-Jyun
TJ
Yao
Bret
B
Zeldow
Paige
P
Williams
Howard J
HJ
Hoffman
George K
GK
Siberry
D000293:Adolescent; D002648:Child; D015658:HIV Infections / Q000453:epidemiology* / Q000503:physiopathology*; D006801:Humans; D016017:Odds Ratio; D017084:Otoacoustic Emissions, Spontaneous; D011446:Prospective Studies