Recent developments in the trifluoromethylation of alkynes.
In the last few years, the development of versatile methodologies to incorporate trifluoromethyl groups into organic molecules has attracted significant attention in synthetic chemistry. This review gives an overview over the development on the trifluoromethylation of alkynes, which have not been solely discussed before. Formation of diverse C(sp, sp(2) , sp(3) )-CF3 bonds are all covered in this review.
State key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000 (China), Fax: (+86) 931-891-2582.
Pin
P
Gao
Xian-Rong
XR
Song
Xue-Yuan
XY
Liu
Yong-Min
YM
Liang
D000480:Alkynes / Q000138:chemical synthesis / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic / Q000379:methods; D054879:Halogenation; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis / Q000737:chemistry*; D008745:Methylation
D000480:Alkynes; D006845:Hydrocarbons, Fluorinated
alkyne; difunctionalization; radical reactions; synthetic methods; trifluoromethylation