Frontal fibrosing alopecia and lichen planopilaris in HLA-identical mother and daughter.
Frontal fibrosing alopecia (FFA) is a lymphocyte-mediated scarring alopecia thought to be a variant of lichen planopilaris (LPP). We present a 67-year-old woman with frontal fibrosing alopecia whose daughter was diagnosed to have lichen planopilaris. Both patients had identical human leukocyte antigen (HLA) D types, supporting a phenotypical relationship between the two clinical entities. Interestingly, our patient also had of autoimmune chronic atrophic gastritis, a previously unreported association.
Department of Dermatology, Complejo Asistencial Universitario de León, Spain.
María Mercedes Otero
MM
Rivas
Sara Calleja
SC
Antolín
Pedro Sánchez
PS
Sambucety
Elia Samaniego
ES
González
José María García
JM
Ruíz de Morales
Manuel Ángel Rodríguez
MÁ
Prieto
D000328:Adult; D000368:Aged; D000505:Alopecia / Q000175:diagnosis* / Q000235:genetics*; D005260:Female; D006681:HLA-D Antigens / Q000235:genetics*; D006801:Humans; D008010:Lichen Planus / Q000175:diagnosis* / Q000235:genetics*; D009035:Mothers; D009679:Nuclear Family; D012536:Scalp Dermatoses / Q000175:diagnosis / Q000235:genetics
D006681:HLA-D Antigens