An approach to fertility preservation in prepubertal and postpubertal females: a critical review of current literature.
Advancements in childhood cancer treatment have led to increasing survivorship, creating a greater emphasis on long-term management of patients, including quality of life and side effects from therapy; foremost of which is preserving fertility. The American Society of Clinical Oncology (ASCO) recently revised their guidelines and recommend fertility preservation options be discussed at the earliest possible opportunity for newly diagnosed patients, including methods available for children that remain investigational. Herein, we discuss the current barriers to and the impact of these guidelines for pediatric oncologists caring for young female patients, and provide some suggestions on how to approach this complicated topic.
Division of Hematology/Oncology The Hospital for Sick Children, University of Toronto, Toronto, Canada.
Samantha
S
Knight
Armando
A
Lorenzo
Anne Marie
AM
Maloney
Amirrtha
A
Srikanthan
Rachel
R
Donen
Ellen
E
Greenblatt
Abha
A
Gupta
D015925:Cryopreservation; D005260:Female; D059247:Fertility Preservation; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D009369:Neoplasms / Q000503:physiopathology / Q000628:therapy*; D010053:Ovary / Q000503:physiopathology; D011627:Puberty
fertility preservation; infertility; pediatric cancer survivor; pediatric oncology; prepubertal females