[Research progress on pharmacology, pharmacokinetics and determination of ergosta-4,6,8 (14),22-tetraen-3-one].
Ergosta-4,6,8(14),22-tetraen-3-one (ergone) is one of main components in many medicinal fungi. Ergone has been reported to possess the activities of diuresis, cytotoxicity, antitumor, immunosuppression, as well as treatment of chronic kidney disease. According to reported literatures, an overview of spectroscopy characteristics, content determination, pharmacological activity and pharmacokinetics, etc. for ergone is presented in this review. Furthermore, the present review can provide a certain reference value for the further study and development of ergone.
Han
H
Chen
Dan-Qian
DQ
Chen
Quan-Fu
QF
Li
Peng-Fei
PF
Li
Hua
H
Chen
Ying-Yong
YY
Zhao
D000818:Animals; D002783:Cholestenones / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000493:pharmacokinetics* / Q000494:pharmacology; D006801:Humans
D002783:Cholestenones; D004365:Drugs, Chinese Herbal; C015860:ergosta-4,6,8(14),22-tetraen-3-one