Third-generation-cephalosporin-resistant Klebsiella pneumoniae isolates from humans and companion animals in Switzerland: spread of a DHA-producing sequence type 11 clone in a veterinary setting.
Characterization of third-generation-cephalosporin-resistant Klebsiella pneumoniae isolates originating mainly from one human hospital (n = 22) and one companion animal hospital (n = 25) in Bern (Switzerland) revealed the absence of epidemiological links between human and animal isolates. Human infections were not associated with the spread of any specific clone, while the majority of animal infections were due to K. pneumoniae sequence type 11 isolates producing plasmidic DHA AmpC. This clonal dissemination within the veterinary hospital emphasizes the need for effective infection control practices.
Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Nadia
N
Wohlwend
Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland.
Andrea
http://orcid.org/0000-0003-3186-5421
A
Endimiani
Small Animal Clinic, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Thierry
T
Francey
Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland vincent.perreten@vetsuisse.unibe.ch.
Vincent
V
Perreten
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000235:genetics; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics; D013557:Switzerland
D000900:Anti-Bacterial Agents; D002511:Cephalosporins