Co-infection of the Siberian hamster (Phodopus sungorus) with a novel Helicobacter sp. and Campylobacter sp.
We report the isolation of a novel helicobacter isolated from the caecum of the Siberian hamster (Phodopus sungorus). Sequence analysis showed 97% sequence similarity to Helicobacter ganmani. In addition, we report the co-infection of these Siberian hamsters with a Campylobacter sp. and a second Helicobacter sp. with 99% sequence similarity to Helicobacter sp. flexispira taxon 8 (Helicobacter bilis), a species isolated previously from patients with bacteraemia. Gross necropsy and histopathology did not reveal any overt pathological lesions of the liver and gastrointestinal tract that could be attributed to the Helicobacter or Campylobacter spp. infections. This is the first helicobacter to be identified in the Siberian hamster and the first report of co-infection of Helicobacter spp. and Campylobacter sp. in asymptomatic Siberian hamsters.
Department of Comparative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Claude M
CM
Nagamine
Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Zeli
Z
Shen
Department of Comparative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Richard H
RH
Luong
Department of Comparative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Gabriel P
GP
McKeon
Department of Biology, Stanford University, Stanford, CA 94305, USA.
Norman F
NF
Ruby
Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
James G
JG
Fox
D000818:Animals; D002167:Campylobacter / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D002169:Campylobacter Infections / Q000150:complications / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D002432:Cecum / Q000382:microbiology; D016000:Cluster Analysis; D060085:Coinfection / Q000150:complications / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D005260:Female; D041981:Gastrointestinal Tract / Q000473:pathology; D016998:Helicobacter / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D016481:Helicobacter Infections / Q000150:complications / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D006651:Histocytochemistry; D008099:Liver / Q000473:pathology; D008297:Male; D008813:Mice, Inbred ICR; D008969:Molecular Sequence Data; D017111:Phodopus; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012376:Rodent Diseases / Q000382:microbiology*; D017422:Sequence Analysis, DNA
D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S