Simplified protocol of cardiac 18F-fluorodeoxyglucose positron emission tomography viability study in normoglycemic patients with known coronary artery disease.
OBJECTIVE
The purpose was to evaluate quality of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) myocardial scans and its correlation with background glucose (BG) after simplified 5% intravenous glucose load protocol.


METHODS
An intravenous glucose load protocol was applied in 69 normoglycemic patients with confirmed coronary artery disease. The blood glucose level was measured every 15 min.


RESULTS
Eighty-four percent of images were optimal, 8.7% suboptimal, and 7.3% uninterpretable. The quality of 18F-FDG-PET was BG independent and body mass index dependent (P=.0007).


CONCLUSIONS
Simplified glucose load protocol is a safe and efficient method of preparation for FDG cardiac viability study in patients with normoglycemia.
Nuclear Medicine Department, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Małgorzata
M
Kobylecka
Nuclear Medicine Department, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Maria Teresa
MT
Płazińska
I-st Chair and Department of Cardiology, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland. Electronic address: tmazurek@kardia.pl.
Tomasz
T
Mazurek
Nuclear Medicine Department, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Adam
A
Bajera
Department of Cardiac Surgery, I Chair and Department of Cardiology, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Anna
A
Słowikowska
Nuclear Medicine Department, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Katarzyna
K
Fronczewska-Wieniawska
Nuclear Medicine Department, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Marek
M
Chojnowski
Nuclear Medicine Department, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Joanna
J
Mączewska
Department of Gastroenterology and Metabolic Diseases, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Marianna
M
Bąk
Nuclear Medicine Department, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Leszek
L
Królicki
D000368:Aged; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*
D019788:Fluorodeoxyglucose F18
Coronary artery disease; FDG-PET/CT; Glucose load protocol; Myocardial perfusion; Myocardial viability