Clinical observations on the treatment of prolapsing hemorrhoids with tissue selecting therapy.
OBJECTIVE
To compare the effects and postoperative complications between tissue selecting therapy stapler (TST) and Milligan-Morgan hemorrhoidectomy (M-M).


METHODS
Four hundred and eighty patients with severe prolapsing hemorrhoids, who were admitted to the Shenyang Coloproctology Hospital between 2009 and 2012, were randomly divided into observation (n=240) and control (n=240) groups. Hemorrhoidectomies were performed with TST in the observation group and with the M-M technique in the control group. The therapeutic effects, operation security, and postoperative complications in the two groups were compared. The immediate and long-term complications were assessed according to corresponding criteria. Pain was assessed on a visual analogue scale. The efficacy was assessed by specialized criteria. The follow-up was conducted one year after the operation.


RESULTS
The total effective rates of the observation and control groups were 99.5% (217/218) and 98.6% (218/221) respectively; the difference was not statistically significant (P=0.322). Their were significant differences between observation and control groups in intraoperative blood loss (5.07±1.14 vs 2.45±0.57, P=0.000), pain (12 h after the surgery: 5.08±1.62 vs 7.19±2.01, P=0.000; at first dressing change: 2.64±0.87 vs 4.34±1.15, P=0.000; first defecation: 3.91±1.47 vs 5.63±1.98, P=0.001), urine retention (n=22 vs n=47, P=0.001), anal pendant expansion after the surgery (2.35±0.56 vs 5.16±1.42, P=0.000), operation time (18.3±5.6 min vs 29.5±8.2 min, P=0.000), and the length of hospital stay (5.3±0.6 d vs 11.4±1.8 d, P=0.000). Moreover TST showed significant reductions compared to M-M in the rates of long-term complications such as fecal incontinence (n=3 vs n=16, P=0.003), difficult bowel movement (n=1 vs n=9, P=0.011), intractable pain (n=2 vs n=12, P=0.007), and anal discharge (n=3 vs n=23, P=0.000).


CONCLUSIONS
TST for severe prolapsing hemorrhoids is a satisfactory technique for more rapid recovery, lower complication rates, and higher operation security.
Zhi-Gang Wang, Yong Zhang, Xian-Dong Zeng, Tie-Hui Zhang, Qi-Dong Zhu, De-Long Liu, Yun-Yu Qiao, Nan Mu, Zhi-Tao Yin, The 5 Department of Anorectal Disease, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, China.
Zhi-Gang
ZG
Wang
Zhi-Gang Wang, Yong Zhang, Xian-Dong Zeng, Tie-Hui Zhang, Qi-Dong Zhu, De-Long Liu, Yun-Yu Qiao, Nan Mu, Zhi-Tao Yin, The 5 Department of Anorectal Disease, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, China.
Yong
Y
Zhang
Zhi-Gang Wang, Yong Zhang, Xian-Dong Zeng, Tie-Hui Zhang, Qi-Dong Zhu, De-Long Liu, Yun-Yu Qiao, Nan Mu, Zhi-Tao Yin, The 5 Department of Anorectal Disease, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, China.
Xian-Dong
XD
Zeng
Zhi-Gang Wang, Yong Zhang, Xian-Dong Zeng, Tie-Hui Zhang, Qi-Dong Zhu, De-Long Liu, Yun-Yu Qiao, Nan Mu, Zhi-Tao Yin, The 5 Department of Anorectal Disease, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, China.
Tie-Hui
TH
Zhang
Zhi-Gang Wang, Yong Zhang, Xian-Dong Zeng, Tie-Hui Zhang, Qi-Dong Zhu, De-Long Liu, Yun-Yu Qiao, Nan Mu, Zhi-Tao Yin, The 5 Department of Anorectal Disease, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, China.
Qi-Dong
QD
Zhu
Zhi-Gang Wang, Yong Zhang, Xian-Dong Zeng, Tie-Hui Zhang, Qi-Dong Zhu, De-Long Liu, Yun-Yu Qiao, Nan Mu, Zhi-Tao Yin, The 5 Department of Anorectal Disease, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, China.
De-Long
DL
Liu
Zhi-Gang Wang, Yong Zhang, Xian-Dong Zeng, Tie-Hui Zhang, Qi-Dong Zhu, De-Long Liu, Yun-Yu Qiao, Nan Mu, Zhi-Tao Yin, The 5 Department of Anorectal Disease, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, China.
Yun-Yu
YY
Qiao
Zhi-Gang Wang, Yong Zhang, Xian-Dong Zeng, Tie-Hui Zhang, Qi-Dong Zhu, De-Long Liu, Yun-Yu Qiao, Nan Mu, Zhi-Tao Yin, The 5 Department of Anorectal Disease, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, China.
Nan
N
Mu
Zhi-Gang Wang, Yong Zhang, Xian-Dong Zeng, Tie-Hui Zhang, Qi-Dong Zhu, De-Long Liu, Yun-Yu Qiao, Nan Mu, Zhi-Tao Yin, The 5 Department of Anorectal Disease, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, China.
Zhi-Tao
ZT
Yin
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical; D002681:China; D003672:Defecation; D005260:Female; D061865:Hemorrhoidectomy / Q000009:adverse effects; D006484:Hemorrhoids / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis / Q000209:etiology; D017060:Patient Satisfaction; D020127:Recovery of Function; D012005:Rectal Prolapse / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D012720:Severity of Illness Index; D017792:Surgical Stapling / Q000009:adverse effects; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
Complication rate; Milligan-Morgan hemorrhoidectomy; Operation security; Severe prolapsing hemorrhoids; Tissue selecting therapy stapler