Traumatic Intracerebral Hemorrhage: Risk Factors Associated with Progression.
The increase in the volume of a traumatic intracerebral hemorrhage (TICH) is a widely studied phenomenon that has a direct impact on the prognosis of patients. The objective of this study was to identify the risk factors associated with the progression of TICH. We retrospectively analyzed the records of 1970 adult patients >15 years of age who were consecutively admitted after sustaining a closed severe traumatic brain injury (TBI) between January 1987 and November 2013 at a single center. Beginning in 2007, patients with moderate TBIs were also included. A total of 782 patients exhibited one or more TICH on the initial CT scan, and met the selection criteria. The main outcome variable was the presence or absence of progression of the TICH. Univariate and multivariate statistical analyses were performed. Factors independently associated with the growth of TICH obtained through logistic regression included the following: an initial volume <5 cc (odds ratio [OR] 2.42, p<0.001), cisternal compression (OR 1.95, p<0.001), decompressive craniectomy (OR 2.18, p<0.001), age (mean 37.67 vs. 42.95 years; OR 1.01, p<0.001), falls as mechanism of trauma (OR 1.72, p=0.001), multiple TICHs (OR 1.56, p=0.007), and hypoxia (OR 1.56, p=0.02). TICH progression occurred with a frequency of 63% in our study. We showed that there was a correlation between TICH growth and some variables, such as multiple TICHs, a lower initial volume, acute subdural hematoma, cisternal compression, older patient age, hypoxia, falls, and decompressive craniectomy.
Department of Neurosurgery, Hospital 12 de Octubre, Universidad Complutense de Madrid , Madrid, Spain .
Santiago
S
Cepeda
Department of Neurosurgery, Hospital 12 de Octubre, Universidad Complutense de Madrid , Madrid, Spain .
Pedro A
PA
Gómez
Department of Neurosurgery, Hospital 12 de Octubre, Universidad Complutense de Madrid , Madrid, Spain .
Ana María
AM
Castaño-Leon
Department of Neurosurgery, Hospital 12 de Octubre, Universidad Complutense de Madrid , Madrid, Spain .
Rafael
R
Martínez-Pérez
Department of Neurosurgery, Hospital 12 de Octubre, Universidad Complutense de Madrid , Madrid, Spain .
Pablo M
PM
Munarriz
Department of Neurosurgery, Hospital 12 de Octubre, Universidad Complutense de Madrid , Madrid, Spain .
Alfonso
A
Lagares
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020202:Cerebral Hemorrhage, Traumatic / Q000000981:diagnostic imaging* / Q000453:epidemiology; D018450:Disease Progression; D005260:Female; D015600:Glasgow Coma Scale; D023261:Glasgow Outcome Scale; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult
TBI; TICH; contusion; intracerebral hematoma; progressive hemorrhagic injury