Reduction in Rotavirus Disease and Sustained Predominance of G2P[4] Rotavirus Strain following Introduction of Rotavirus Vaccine in Recife, Brazil.
Rotavirus vaccination was introduced in Brazil in March 2006. We describe the distribution of rotavirus genotypes in children with acute gastroenteritis in a hospital in Recife, Brazil, during pre- and post-vaccination periods. There was a 43.8% reduction in the proportion of diarrhea episodes due to rotavirus. Nevertheless, we observed a sustained predominance of G2P[4] as the main genotype identified in the post-vaccination period.
Research Department, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil fmum@hotmail.com.
Fernanda Maria Ulisses
FM
Montenegro
Research Department, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil.
Ana Rodrigues
AR
Falbo
Research Department, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil.
Eliane Mendes
EM
Germano
Research Department, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil.
Nancy Barros
NB
Correia
Research Department, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil.
Edvaldo da Silva
Eda S
Souza
Division of Molecular Epidemiology, Graduate School of Biomedical Sciences and Global Centre of Excellence, Nagasaki University, Nagasaki, Japan Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, UK.
Osamu
O
Nakagomi
Division of Molecular Epidemiology, Graduate School of Biomedical Sciences and Global Centre of Excellence, Nagasaki University, Nagasaki, Japan Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, UK.
Toyoko
T
Nakagomi
Liverpool School of Tropical Medicine, Liverpool, UK.
Luis E
LE
Cuevas
Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, UK.
Nigel A
NA
Cunliffe
Research Department, Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil.
Jailson B
JB
Correia
D001938:Brazil / Q000453:epidemiology; D002675:Child, Preschool; D005243:Feces / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology / Q000517:prevention & control / Q000821:virology; D005838:Genotype; D006801:Humans; D007223:Infant; D008297:Male; D011159:Population Surveillance; D012367:RNA, Viral / Q000235:genetics; D012401:Rotavirus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology*; D022243:Rotavirus Vaccines / Q000008:administration & dosage / Q000276:immunology*; D014611:Vaccination
D012367:RNA, Viral; D022243:Rotavirus Vaccines
gastroenteritis; genotype; rotavirus; rotavirus vaccine