Chromosome segregation in Vibrio cholerae.
The study of chromosome segregation is currently one of the most exciting research frontiers in cell biology. In this review, we discuss our current knowledge of the chromosome segregation process in Vibrio cholerae, based primarily on findings from fluorescence microscopy experiments. This bacterium is of special interest because of its eukaryotic feature of having a divided genome, a feature shared with 10% of known bacteria. We also discuss how the segregation mechanisms of V. cholerae compare with those in other bacteria, and highlight some of the remaining questions regarding the process of bacterial chromosome segregation.
Laboratory of Biochemistry and Molecular Biology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, Md., USA.
Revathy
R
Ramachandran
Jyoti
J
Jha
Dhruba K
DK
Chattoraj
D020090:Chromosome Segregation; D002876:Chromosomes, Bacterial / Q000502:physiology*; D008856:Microscopy, Fluorescence; D014734:Vibrio cholerae / Q000235:genetics / Q000502:physiology*