[A case of adenocarcinoma of the anal canal in which palliation was achieved by chemoradiotherapy].
An 82-year-old man who complained of constipation, anal pain, and bleeding was diagnosed with internal hemorrhoid in another hospital 6 months previously. At the time of our consultation, a tumor was observed in the anal canal. Computed tomography (CT) imaging revealed that the tumor extended to the front of the coccyx with abscess formation. Histological examination of biopsy specimens confirmed a diagnosis of adenocarcinoma. Since the patient refused to undergo surgery, we recommended chemoradiotherapy for relieving pain. A total of 60 Gy of irradiation was administered to the lesser pelvis, and chemotherapy was initiated with S-1 at a dose of 8 0mg/day for 14 consecutive days followed by 7 days of rest. Subsequently, tumor reduction was seen and the pain was controlled. The patient showed improvement in activities of daily living (ADL). Currently, the patient continues to receive S-1 therapy. We conclude that chemoradiotherapy is useful as a palliative therapy in anal mucinous carcinoma.
Dept. of Surgery, Teramoto Memorial Hospital.
Nobuo
N
Matsunaga
Yasuo
Y
Nakagawa
Kenichi
K
Yanagawa
D000230:Adenocarcinoma / Q000628:therapy*; D000369:Aged, 80 and over; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001005:Anus Neoplasms / Q000628:therapy*; D059248:Chemoradiotherapy; D004338:Drug Combinations; D006801:Humans; D008297:Male; D010094:Oxonic Acid / Q000627:therapeutic use*; D010166:Palliative Care; D005641:Tegafur / Q000627:therapeutic use*
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid