[Parathyroid Hormone-related Peptide (PTHrP) Producing Lung Cancer Presenting Hypercalcemia; Report of a Case].
An 82-year-old man was admitted to our hospital with hemoptysis and weight loss. Chest computed tomography(CT) showed a 90 mm mass with cavity formation in the right lower lobe adjacent to chest wall. Laboratory data revealed hypercalcemia and elevation of parathyroid hormone-related protein C (PTHrP). He was diagnosed as squamous cell carcinoma of lung by transbronchial lung biopsy (TBLB) [cT3aN1M0]. Nausea and anorexia due to hypercalcemia became worse and a right middle and lower lobectomy was performed because of difficult control of symptoms by medicine and worsening of his general condition. His symptoms were improved immediately after surgery.
Division of Thoracic Surgery, Toyota Kosei Hospital, Toyota, Japan.
Takehiko
T
Okagawa
Yoshinori
Y
Hiramatsu
D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000378:metabolism* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008175:Lung Neoplasms / Q000150:complications / Q000378:metabolism* / Q000473:pathology / Q000601:surgery*; D008297:Male; D010257:Paraneoplastic Syndromes / Q000209:etiology*; D044162:Parathyroid Hormone-Related Protein / Q000096:biosynthesis*; D011013:Pneumonectomy; D016896:Treatment Outcome
D044162:Parathyroid Hormone-Related Protein