A SEmi-Adiabatic matched-phase spin echo (SEAMS) PINS pulse-pair for B1 -insensitive simultaneous multislice imaging.
OBJECTIVE
Simultaneous multislice (SMS) imaging is a powerful technique that can reduce image acquisition time for anatomical, functional, and diffusion weighted magnetic resonance imaging. At higher magnetic fields, such as 7 Tesla, increased radiofrequency (RF) field inhomogeneity, power deposition, and changes in relaxation parameters make SMS spin echo imaging challenging. We designed an adiabatic 180° Power Independent of Number of Slices (PINS) pulse and a matched-phase 90° PINS pulse to generate a SEmi-Adiabatic Matched-phase Spin echo (SEAMS) PINS sequence to address these issues.


METHODS
We used the adiabatic Shinnar Le-Roux (SLR) algorithm to generate a 180° pulse. The SLR polynomials for the 180° pulse were then used to create a matched-phase 90° pulse. The pulses were sub-sampled to produce a SEAMS PINS pulse-pair and the performance of this pulse-pair was validated in phantoms and in vivo.


RESULTS
Simulations as well as phantom and in vivo results, demonstrate multislice capability and improved B1 -insensitivity of the SEAMS PINS pulse-pair when operating at RF amplitudes of up to 40% above adiabatic threshold.


CONCLUSIONS
The SEAMS PINS approach presented here achieves multislice spin echo profiles with improved B1 -insensitivity when compared with a conventional spin echo.
Translational and Molecular Imaging Institution, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Rebecca E
RE
Feldman
Bioengineering Department, Stanford University, Stanford, California, USA.
Haisam M
HM
Islam
Translational and Molecular Imaging Institution, Icahn School of Medicine at Mount Sinai, New York, New York, USA.|Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, USA.
Junqian
J
Xu
Translational and Molecular Imaging Institution, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Priti
P
Balchandani
D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology*; D064368:Healthy Volunteers; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019047:Phantoms, Imaging; D059629:Signal-To-Noise Ratio
MRI; PINS; SEAMS; SEmi-Adiabatic Matched-Phase Spin Echo; power independent of number of slices; simultaneous multi-slice; spin echo; ultrahigh field