Benign metachronous bilateral ovarian and mediastinal teratomas with an elevated alpha-fetoprotein.
Teratomas are a common form of non-seminomatous germ cell tumor histologically composed of tissues derived from multiple cell lines of the primary embryonic germ cell layers. There are few cases reported in the literature that describe multiple locations with recurrence of benign teratomas, none of which describe an elevated AFP. We describe a case of metachronous bilateral recurrent ovarian and mediastinal teratomas with a curiously elevated α-fetoprotein. We may be describing a novel syndrome of recurrent metachronous teratomas. Because of the uncertainty of this case, the patient will require close follow-up over the next several years.
Helen F. Graham Cancer Center, Christiana Care Health System, Wilmington, Delaware.
Michael Z
MZ
Caposole
General Surgery Residency, Christiana Care Health System, Wilmington, Delaware.
Veronica
V
Aruca-Bustillo
Department of Pathology, Christiana Care Health System, Wilmington, Delaware.
Mark
M
Mitchell
Helen F. Graham Cancer Center, Christiana Care Health System, Wilmington, Delaware; Department of Thoracic Surgery, Christiana Care Health System, Wilmington, Delaware. Electronic address: bnam@christianacare.org.
Brian
B
Nam
D000328:Adult; D005260:Female; D006801:Humans; D008479:Mediastinal Neoplasms / Q000097:blood*; D016609:Neoplasms, Second Primary / Q000097:blood*; D010051:Ovarian Neoplasms / Q000097:blood*; D013724:Teratoma / Q000097:blood*; D000509:alpha-Fetoproteins / Q000032:analysis*
D000509:alpha-Fetoproteins