Hypervirulent Klebsiella pneumoniae.
Hypervirulent strains of Klebsiella pneumoniae are associated with abscess formation, commonly hepatic, and metastatic spread, even in healthy patients. We describe a case of this clinical syndrome, genotypic and phenotypic features of the isolate, and briefly review epidemiology, clinical manifestations, and pathogenesis of this underappreciated syndrome.
Division of Infectious Diseases, Department of Internal Medicine, Beth Israel Deaconess Medical Center , Harvard Medical School , Boston, Massachusetts.
Payal K
PK
Patel
Veterans Administration Western New York Healthcare System, Buffalo, New York ; Departments of Medicine ; Microbiology and Immunology , University at Buffalo-State University of New York , Buffalo, New York.
Thomas A
TA
Russo
Division of Infectious Diseases, Department of Internal Medicine, Beth Israel Deaconess Medical Center , Harvard Medical School , Boston, Massachusetts.
Adolf W
AW
Karchmer
Klebsiella pneumoniae; hypermucoviscous; hypervirulence; virulence factors