Diagnostic capacity of non-echo planar diffusion-weighted MRI in the detection of primary and recurrent cholesteatoma.
OBJECTIVE
the aim of this study was to determine the certainty of non-echo-planar imaging diffusion-weighted magnetic resonance imaging (non-EPI DW MRI) in the diagnosis of primary and recurrent cholesteatoma in patients with clinical suspicion of cholesteatoma, assessing the sensitivity and specificity of the test in both groups.


METHODS
Seventy-five patients with clinical suspicion of cholesteatoma were included in our study. Forty-eight cases had primary suspicion of cholesteatoma and 27 cases had recurrent suspicion of cholesteatoma. All patients received non-EPI DW MRI tests before surgery, and radiological and surgical findings were compared.


RESULTS
Sensitivity, specificity and the positive and negative predictive value for primary diagnosis of cholesteatoma group were 91.2%, 50%, 81.6% and 70%, respectively. For the recurrent cholesteatoma group these results were 100%, 66.7%, 90.9% and 100%, respectively.


CONCLUSIONS
Non-echo-planar imaging diffusion-weighted magnetic resonance imaging is a high sensitivity imaging test for detecting cholesteatoma, for both primary diagnosis and for recurrent cases.
Departamento ENT, Hospital Universitario Rey Juan Carlos, Móstoles, Madrid, España. Electronic address: lauragarridogarcia@gmail.com.
Laura
L
Garrido
Departamento ENT, Hospital Universitario Fundación Jiménez Díaz, Universidad Autónoma, Madrid, España.
Carlos
C
Cenjor
Departamento Radiología, Hospital Universitario Fundación Jiménez Díaz, Universidad Autónoma, Madrid, España.
Julia
J
Montoya
Departamento Radiología, Hospital Universitario Rey Juan Carlos, Móstoles, Madrid, España.
Ana
A
Alonso
Departamento ENT, Hospital Universitario Rey Juan Carlos, Móstoles, Madrid, España.
Jose
J
Granell
Departamento ENT, Hospital Universitario Rey Juan Carlos, Móstoles, Madrid, España.
Raimundo
R
Gutiérrez-Fonseca
D018424:Cholesteatoma, Middle Ear / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000601:surgery; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006801:Humans; D059906:Neuroimaging / Q000379:methods*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012008:Recurrence; D012680:Sensitivity and Specificity
Cholesteatoma; Colesteatoma; Magnetic resonance imaging; Non-echo-planar diffusion-weight; Resonancia magnética; Técnica de difusión no eco-planar