Anaplastic large cell lymphoma associated with breast implant: a case report.
Primary breast lymphoma represents less than 1% of all primary breast malignancies and most primary breast lymphomas are of B-Cell origin. The association of anaplastic lymphoma kinase (ALK) negative anaplastic large cell lymphoma (ALCL), a very rare form of primary breast lymphoma, with silicone-filled breast implants has been suggested and several case reports supported this proposal, especially in Western countries. Here we describe one of the first cases of primary breast ALK-negative ALCL in association with saline-filled silicone breast implants evaluated in Iran, where the rising number of breast reconstructive and aesthetic surgeries would commit both surgical pathologists and plastic surgeons to be familiar with this entity.
Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran.
Afsaneh
A
Rajabiani
Plastic surgeon, Parsian Hospital, Tehran, Iran.
Hosein
H
Arab
Department of Plastic and Reconstructive Surgery, Tehran University of Medical Sciences, Tehran, Iran.
Abolhasan
A
Emami
Department of Plastic and Reconstructive Surgery, Tehran University of Medical Sciences, Tehran, Iran.
Ali
A
Manafi
Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran.
Navid
N
Bazzaz
Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran.
Hiva
H
Saffar
Anaplastic Large Cell Lymphoma; Anaplastic Lymphoma Kinase; Silicone breast implant