[Medial longitudinal fasciculus (MLF) syndrome in a patient with giant cell arteritis].
A 76-year-old female was referred to our department because of diplopia for two months and intermittent claudication for five months. She showed medial longitudinal fasciculus (MLF) syndrome. Brain MRI (T2WI) showed multiple infarctions in the right pontine tegmentum and left paramedian midbrain. A biopsy of superficial temporal artery showed the characteristic findings of glanulomatous inflammation indicative of giant cell arteritis. We thought the mechanism of this cerebral infarction as artery to artery embolization or intracranial arteritis. Treatment with oral prednisolone (1 mg/kg/day) improved her limb claudication and normalized serum C-reactive protein level.
Division of Neurology, Kobe University Graduate School of Medicine.
Takeshi
T
Uenaka
Hirotoshi
H
Hamaguchi
Kenji
K
Sekiguchi
Hisatomo
H
Kowa
Fumio
F
Kanda
Tatsushi
T
Toda
D000284:Administration, Oral; D000368:Aged; D002544:Cerebral Infarction / Q000175:diagnosis / Q000209:etiology*; D038524:Diffusion Magnetic Resonance Imaging; D004172:Diplopia / Q000209:etiology*; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007383:Intermittent Claudication / Q000209:etiology*; D008636:Mesencephalon; D065821:Pontine Tegmentum; D011239:Prednisolone / Q000008:administration & dosage; D013577:Syndrome; D013699:Temporal Arteries / Q000473:pathology; D016896:Treatment Outcome
D011239:Prednisolone