Cohort Profile: The Shanghai Men's Health Study.
The Shanghai Men's Health Study (SMHS) is a population-based cohort study of 61,480 men aged 40-74 years, launched in 2002 in urban Shanghai to investigate the contribution of lifestyle/environmental factors and genetic susceptibility to cancer and other non-communicable diseases (NCDs). At baseline, trained interviewers collected detailed information on personal and dietary habits, occupational/medical history and physical activity, and took anthropometric measurements (response rate: 74%). Blood, urine and DNA were collected from 75%, 89% and 89% of participants, respectively. The cohort has been followed up through a combination of in-person surveys every 3-4 years and annual record linkage with cancer and vital statistics registries. Response rates for in-person follow-up surveys were over 91% and coverage for mortality nearly 100%. SMHS participants have a high smoking rate (58.6%) and moderate alcohol-drinking rate (29.3%), but low obesity rate (2.6%). They have a low calorie intake from fat (16.2% of total calorie intake) and protein (16.4%), high calorie intake from carbohydrates (67.4%), and high intake of soy food, cruciferous vegetables and fish (156.5, 110.6 and 51.7 g/day, respectively). With its unique exposure pattern and wealth of data and biological samples, the SMHS is well positioned for long-term research into NCD aetiology and prognosis. Information about accessing the SMHS resources can be found at: http://www.mc.vanderbilt.edu/swhs-smhs/.
Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA and xiao-ou.shu@vanderbilt.edu.
Xiao-Ou
XO
Shu
Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Honglan
H
Li
Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA and.
Gong
G
Yang
Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Jing
J
Gao
Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA and.
Hui
H
Cai
Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA and.
Yumie
Y
Takata
Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, USA and.
Wei
W
Zheng
Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yong-Bing
YB
Xiang
D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000453:epidemiology; D002423:Cause of Death; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D004777:Environment; D005247:Feeding Behavior; D020022:Genetic Predisposition to Disease; D006801:Humans; D008019:Life Style; D008297:Male; D054526:Men's Health; D008875:Middle Aged; D009043:Motor Activity; D009369:Neoplasms / Q000453:epidemiology; D009765:Obesity / Q000453:epidemiology; D012307:Risk Factors; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D064424:Tobacco Use; D014505:Urban Population / Q000706:statistics & numerical data