title: Cell biology: scaling and the emergence of evolutionary cell biology.
abstract: A new study investigating the origins of diversity in the structure of the mitotic spindle in nematode embryos, at timescales spanning a few generations to hundreds of millions of years, finds that most features of the spindle evolve via a scaling relationship generated by natural selection acting directly upon embryo size.
authors.affiliation: Institute of Ecology and Evolution, Institute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA. Electronic address: pphil@uoregon.edu.
authors.forename: Patrick C
authors.initials: PC
authors.lastname: Phillips
authors.affiliation: Institute of Ecology and Evolution, Institute of Molecular Biology, University of Oregon, Eugene, OR 97403, USA.
authors.forename: Bruce
authors.initials: B
authors.lastname: Bowerman
mesh_terms: D000818:Animals; D005075:Biological Evolution; D017173:Caenorhabditis elegans / Q000196:embryology / Q000235:genetics / Q000648:ultrastructure; D003585:Cell Biology; D020090:Chromosome Segregation; D004625:Embryo, Nonmammalian / Q000648:ultrastructure; D012641:Selection, Genetic; D008941:Spindle Apparatus / Q000648:ultrastructure