title: Copper-catalyzed aerobic oxidative cleavage of C-C bonds in epoxides leading to aryl nitriles and aryl aldehydes.
abstract: Novel copper-catalyzed aerobic synthesis of aryl nitriles and aldehydes from epoxides via C-C single bond cleavage has been discovered. This reaction provides a practical method toward the synthesis of aryl nitriles and aldehydes, which are versatile intermediates and building blocks in organic synthesis.
authors.affiliation: Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, Yunnan 650500, China. gulijun2005@126.com.
authors.forename: Lijun
authors.initials: L
authors.lastname: Gu
authors.forename: Cheng
authors.initials: C
authors.lastname: Jin
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D004852:Epoxy Compounds / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D000447:Aldehydes; D004852:Epoxy Compounds; D009570:Nitriles; D002244:Carbon; D003300:Copper