title: Developmental and morphological studies in Japanese medaka with ultra-high resolution optical coherence tomography.
abstract: We propose ultra-high resolution optical coherence tomography to study the morphological development of internal organs in medaka fish in the post-embryonic stages at micrometer resolution. Different stages of Japanese medaka were imaged after hatching in vivo with an axial resolution of 2.8 µm in tissue. Various morphological structures and organs identified in the OCT images were then compared with the histology. Due to the medaka's close resemblance to vertebrates, including humans, these morphological features play an important role in morphogenesis and can be used to study diseases that also occur in humans.
authors.affiliation: Center for Optical Research and Education (CORE), Utsunomiya University, Japan.
authors.forename: Fanny Moses
authors.initials: FM
authors.lastname: Gladys
authors.affiliation: Center for Bioscience Research and Education, Utsunomiya University, Japan.
authors.forename: Masaru
authors.initials: M
authors.lastname: Matsuda
authors.affiliation: Center for Optical Research and Education (CORE), Utsunomiya University, Japan.
authors.forename: Yiheng
authors.initials: Y
authors.lastname: Lim
authors.affiliation: Center for Optical Research and Education (CORE), Utsunomiya University, Japan.
authors.forename: Boaz Jessie
authors.initials: BJ
authors.lastname: Jackin
authors.affiliation: Center for Bioscience Research and Education, Utsunomiya University, Japan ; United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology, Japan.
authors.forename: Takuto
authors.initials: T
authors.lastname: Imai
authors.affiliation: Center for Optical Research and Education (CORE), Utsunomiya University, Japan.
authors.forename: Yukitoshi
authors.initials: Y
authors.lastname: Otani
authors.affiliation: Center for Optical Research and Education (CORE), Utsunomiya University, Japan.
authors.forename: Toyohiko
authors.initials: T
authors.lastname: Yatagai
authors.affiliation: Center for Optical Research and Education (CORE), Utsunomiya University, Japan.
authors.forename: Barry
authors.initials: B
authors.lastname: Cense
keywords: (170.3880) Medical and biological imaging; (170.4500) Optical coherence tomography