title: [A case of anaphylaxis caused by enokitake (Flammulina velutipes) ingestion].
abstract: Enokitake (Flammulina velutipes, winter mushroom) is a common edible mushroom in Japan. We experienced a case of anaphylaxis after enokitake ingestion. There are no reports describing anaphylaxis caused by the ingestion of this mushroom. Enokitake allergen has also not been reported. We thus attempted to identify enokitake allergen using the patient's serum. The patient was a seventeen-year-old woman who had had no episodes of food allergy and experienced anaphylaxis after the ingestion of sukiyaki (beef, pork, tofu, vegetables, enokitake, etc.). She had previously eaten sukiyaki (the same ingredients) without any symptoms. The result of enokitake skin prick to prick test was positive. Oral food challenge was positive, inducing anaphylaxis. We performed western blotting with enokitake extract and the patient's serum. Three enokitake protein bands (18 kDa, 39 kDa, 50 kDa) reacted specifically with the patient's IgE.
authors.affiliation: Department of Pediatrics, Okinawa Kyodo Hospital.
authors.forename: Kenta
authors.initials: K
authors.lastname: Otsuji
authors.affiliation: Department of Pediatrics, Okinawa Kyodo Hospital.
authors.forename: Kaori
authors.initials: K
authors.lastname: Ohara
authors.affiliation: Department of Pediatrics, Okinawa Kyodo Hospital.
authors.forename: Maki
authors.initials: M
authors.lastname: Nakamura
authors.affiliation: Department of Pediatrics, Okinawa Kyodo Hospital.
authors.forename: Ryoko
authors.initials: R
authors.lastname: Amazumi
authors.affiliation: Department of Pediatrics, Okinawa Kyodo Hospital.
authors.forename: Chiaki
authors.initials: C
authors.lastname: Higa
authors.affiliation: Department of Pediatrics, Okinawa Kyodo Hospital.|Urasoe Kyodo Clinic.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kakazu
authors.affiliation: Department of Pediatrics, Fujita Health University Banbuntanehoutokukai Hospital.
authors.forename: Yasuto
authors.initials: Y
authors.lastname: Kondo
mesh_terms: D000293:Adolescent; D000485:Allergens / Q000737:chemistry / Q000276:immunology; D000707:Anaphylaxis / Q000276:immunology*; D004435:Eating; D005260:Female; D055393:Flammulina / Q000276:immunology*; D005512:Food Hypersensitivity / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D008970:Molecular Weight
chemical_list: D000485:Allergens; D007073:Immunoglobulin E