title: Lymph node flap transfer for patients with secondary lower limb lymphedema.
abstract: BACKGROUND
  Previous authors have shown benefits from the use of lymph node flap transfer (LNFT) to treat lymphedema of the arms, but there is little evidence for its use for lower limb lymphedema. We performed a retrospective analysis of a series of patients suffering from secondary lower limb lymphedema treated with a free LNFT.
  
  
  METHODS
  52 cases of LNFT to treat 41 legs in 38 patients with secondary lymphedema were retrospectively reviewed. The causes of the lymphedema included lymphedema secondary to hysterectomy for uterine cancer, melanoma resections on the leg, lymphoma treatment and testicular cancer, cosmetic surgery to the limb, lipoma resection at the inguinal region, and a saphenectomy. Patients had been suffering with lymphedema for an average of 9.1 ± 7.3 years at the time of LNFT.
  
  
  RESULTS
  Eleven patients (28.9%) presented with minor complications treated conservatively. For 23 legs there was enough data to follow limb volume evolution after a single LNFT. Total volume reduction in eight legs (two patients with no measures of the healthy limb and three bilateral) was 7.1 ± 8.6%. Another group of 15 patients with unilateral lymphedema had an average 46.3 ± 34.7% reduction of excess volume. Better results (>30% REV) were associated with smaller preoperative excess volume (P = 0.045).
  
  
  CONCLUSIONS
  Patients with secondary leg lymphedema can benefit from LNFT. Results in patients with mild presentations seem to be better than in more severe cases. © 2014 Wiley Periodicals, Inc. Microsurgery 37:29-33, 2017.
authors.affiliation: Plastic Surgery Department, Medical School of the University of São Paulo, São Paulo, Brazil.|Instituto de Ensino e Pesquisa, Hospital Sírio-Libanês, São Paulo, Brazil.
authors.forename: Bernardo N
authors.initials: BN
authors.lastname: Batista
authors.affiliation: Lymphoedema Center, Clinique Jouvenet, Paris, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Germain
authors.affiliation: Plastic Surgery Department, Medical School of the University of São Paulo, São Paulo, Brazil.|Instituto de Ensino e Pesquisa, Hospital Sírio-Libanês, São Paulo, Brazil.
authors.forename: José Carlos M
authors.initials: JC
authors.lastname: Faria
authors.affiliation: Lymphoedema Center, Clinique Jouvenet, Paris, France.
authors.forename: Corinne
authors.initials: C
authors.lastname: Becker
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D058752:Free Tissue Flaps / Q000637:transplantation*; D006801:Humans; D008198:Lymph Nodes / Q000637:transplantation*; D008209:Lymphedema / Q000209:etiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult