title: Oral allergy syndrome (pollen-food allergy syndrome).
abstract: Oral allergy syndrome (OAS) or pollen-food allergy syndrome (PFS) is a hypersensitivity reaction to plant-based foods, manifesting most commonly with pruritus of the lips, tongue, and mouth. Unlike simple food allergy, OAS requires prior sensitization to a cross-reacting inhalant allergen rather than direct sensitization to a specific food protein. In this review, we summarize the clinical features and pathophysiology of OAS and provide an overview of known pollen-food associations.
authors.affiliation: From the *New York University School of Medicine, New York, NY; †The Ronald O. Perelman Department of Dermatology, New York, NY; and ‡Massachusetts General Hospital Department of Dermatology, Harvard Medical School, Boston, MA.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Price
authors.forename: Sarika
authors.initials: S
authors.lastname: Ramachandran
authors.forename: Gideon P
authors.initials: GP
authors.lastname: Smith
authors.forename: Mary L
authors.initials: ML
authors.lastname: Stevenson
authors.forename: Miriam K
authors.initials: MK
authors.lastname: Pomeranz
authors.forename: David E
authors.initials: DE
authors.lastname: Cohen
mesh_terms: D003429:Cross Reactions / Q000276:immunology; D004435:Eating; D005512:Food Hypersensitivity / Q000209:etiology* / Q000276:immunology; D005638:Fruit / Q000009:adverse effects* / Q000276:immunology; D006801:Humans; D019570:Inhalation Exposure; D009059:Mouth Diseases / Q000209:etiology* / Q000276:immunology; D011537:Pruritus / Q000209:etiology* / Q000276:immunology; D006255:Rhinitis, Allergic, Seasonal / Q000209:etiology* / Q000276:immunology; D014675:Vegetables / Q000009:adverse effects* / Q000276:immunology