title: Acute rheumatic fever and rheumatic heart disease in resource-limited settings.
abstract: Poststreptococcal complications, such as acute rheumatic fever (ARF) and rheumatic heart disease (RHD), are common in resource-limited settings, with RHD recognised as the most common cause of paediatric heart disease worldwide. Managing these conditions in resource-limited settings can be challenging. We review the investigation and treatment options for ARF and RHD and, most importantly, prevention methods in an African setting.
authors.affiliation: Gambia Unit, Medical Research Council, Fajara, The Gambia.
authors.forename: Gabriella
authors.initials: G
authors.lastname: Watson
authors.affiliation: Gambia Unit, Medical Research Council, Fajara, The Gambia.
authors.forename: Bintou
authors.initials: B
authors.lastname: Jallow
authors.affiliation: Gambia Unit, Medical Research Council, Fajara, The Gambia Wellcome Centre for Global Health Research, Imperial College, London, UK.
authors.forename: Kirsty
authors.initials: K
authors.lastname: Le Doare
authors.affiliation: Department of Congenital Heart Disease, Evelina London Children's Hospital, Guy's & St Thomas' NHS Foundation Trust, London, UK.
authors.forename: Kuberan
authors.initials: K
authors.lastname: Pushparajah
authors.affiliation: Gambia Unit, Medical Research Council, Fajara, The Gambia.
authors.forename: Suzanne T
authors.initials: ST
authors.lastname: Anderson
mesh_terms: D000293:Adolescent; D000349:Africa; D005260:Female; D006801:Humans; D008297:Male; D008507:Medically Underserved Area; D011322:Primary Prevention; D012213:Rheumatic Fever / Q000175:diagnosis / Q000517:prevention & control* / Q000601:surgery; D012214:Rheumatic Heart Disease / Q000175:diagnosis / Q000517:prevention & control* / Q000601:surgery; D055502:Secondary Prevention; D013290:Streptococcal Infections / Q000517:prevention & control; D022541:Streptococcal Vaccines
chemical_list: D022541:Streptococcal Vaccines
keywords: acute rheumatic fever; group A stretococcus; management; resource-limited setting; rheumatic heart disease