title: Antibiotic Resistance of Listeria monocytogenes Isolated from Meat-Processing Environments, Beef Products, and Clinical Cases in Brazil.
abstract: The present study aimed to assess the antimicrobial resistance and the presence of virulence markers in 137 Listeria monocytogenes isolates obtained from meat-processing environments, beef products, and clinical cases. All isolates were subject to molecular serogrouping and their antibiotic resistance profiles were assessed against 12 antimicrobials. In addition, isolates were subjected to detection of virulence marker genes (inlA, inlC, inlJ). The isolates were classified into serogroups 4b, 4d, 4a, or 4c (46%), 1/2c or 3c (27%), 1/2a or 3a (13.9%), and 1/2b or 3b (13.1%). All tested isolates presented sensitivity to the majority of the tested antimicrobials, but most of them presented resistance or intermediate resistance to clindamycin (88.3%) and oxacillin (73.7%). Virulence markers were detected in all isolates, demanding further analysis to better characterize their pathogenic potential.
authors.affiliation: 1 Departamento de Veterinária, Universidade Federal de Viçosa , Viçosa, Minas Gerais, Brazil .
authors.forename: Anderson Carlos
authors.initials: AC
authors.lastname: Camargo
authors.affiliation: 1 Departamento de Veterinária, Universidade Federal de Viçosa , Viçosa, Minas Gerais, Brazil .
authors.forename: Natalia Parma Augusto
authors.initials: NP
authors.lastname: de Castilho
authors.affiliation: 1 Departamento de Veterinária, Universidade Federal de Viçosa , Viçosa, Minas Gerais, Brazil .
authors.forename: Danilo Augusto Lopes
authors.initials: DA
authors.lastname: da Silva
authors.affiliation: 2 Laboratório de Zoonoses Bacterianas, Instituto Oswaldo Cruz , Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil .
authors.forename: Deyse Christina
authors.initials: DC
authors.lastname: Vallim
authors.affiliation: 2 Laboratório de Zoonoses Bacterianas, Instituto Oswaldo Cruz , Fundação Oswaldo Cruz, Rio de Janeiro, Rio de Janeiro, Brazil .
authors.forename: Ernesto
authors.initials: E
authors.lastname: Hofer
authors.affiliation: 1 Departamento de Veterinária, Universidade Federal de Viçosa , Viçosa, Minas Gerais, Brazil .
authors.forename: Luís Augusto
authors.initials: LA
authors.lastname: Nero
mesh_terms: D000818:Animals; D001938:Brazil / Q000453:epidemiology; D002417:Cattle; D002981:Clindamycin / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D005525:Food-Processing Industry; D005798:Genes, Bacterial / Q000235:genetics; D008089:Listeria monocytogenes / Q000187:drug effects* / Q000472:pathogenicity; D008460:Meat / Q000382:microbiology*; D010068:Oxacillin / Q000494:pharmacology; D016133:Polymerase Chain Reaction; D037521:Virulence Factors / Q000235:genetics
chemical_list: D037521:Virulence Factors; D002981:Clindamycin; D010068:Oxacillin