title: [Cutaneous and subcutaneous leiomyosarcoma: report of two cases].
abstract: Cutaneous leiomyosarcomas are uncommon malignant tumors of smooth muscle. We report herein two cases of cutaneous leiomyosarcoma, one of dermal and other of subcutaneous vascular origin, confirmed by histology and immunohistochemistry. Both cases were treated with wide surgical excision, one with local recurrence. No metastases were detected at follow-up. Leiomyosarcomas should be considered in lesions with histologic features of spindle cell malignancy. It is necessary in most of the cases a histological differentiation with specific immunohistochemical markers. The treatment of choice is radical excision with wide margins, achieving satisfactory results.
authors.affiliation: Dermatology Department, Pius Hospital de Valls.
authors.forename: Paola
authors.initials: P
authors.lastname: Pasquali
authors.forename: Azael
authors.initials: A
authors.lastname: Freites-Martinez
authors.forename: Carmen
authors.initials: C
authors.lastname: Hernandez
authors.forename: Jesús
authors.initials: J
authors.lastname: Valero Lugo
authors.forename: Ángeles
authors.initials: Á
authors.lastname: Fortuño
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D007150:Immunohistochemistry; D007890:Leiomyosarcoma / Q000473:pathology* / Q000601:surgery; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D040521:Subcutaneous Tissue / Q000473:pathology* / Q000601:surgery