title: A novel method for delineation of oral mucosa for radiotherapy dose-response studies.
abstract: There is currently no standard method for delineating the oral mucosa and most attempts are oversimplified. A new method to obtain anatomically accurate contours of the oral mucosa surfaces was developed and applied to 11 patients. This is expected to represent an opportunity for improved toxicity modelling of oral mucositis.
authors.affiliation: Joint Department of Physics at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, UK. Electronic address: jamie.dean@icr.ac.uk.
authors.forename: Jamie A
authors.initials: JA
authors.lastname: Dean
authors.affiliation: Head and Neck Unit, The Royal Marsden NHS Foundation Trust, London, UK.
authors.forename: Liam C
authors.initials: LC
authors.lastname: Welsh
authors.affiliation: Joint Department of Physics at The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, UK.
authors.forename: Sarah L
authors.initials: SL
authors.lastname: Gulliford
authors.affiliation: Head and Neck Unit, The Royal Marsden NHS Foundation Trust, London, UK.
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Harrington
authors.affiliation: Head and Neck Unit, The Royal Marsden NHS Foundation Trust, London, UK.
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Nutting
mesh_terms: D006801:Humans; D009061:Mouth Mucosa / Q000033:anatomy & histology* / Q000528:radiation effects*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000009:adverse effects / Q000379:methods*; D013280:Stomatitis / Q000209:etiology*
keywords: Contouring; Delineation; Dose–response; Oral mucosa; Oral mucositis