title: Spectrum of Uveitis in A German Tertiary Center: Review of 474 Consecutive Patients.
abstract: OBJECTIVE
  To analyze the spectrum of uveitis at a German tertiary center.
  
  
  METHODS
  A total of 474 consecutive patients with uveitis were classified according to the primary anatomic site of inflammation, examined for laterality of disease, and screened for etiologies.
  
  
  RESULTS
  Out of the total, 253 patients (53%) had anterior uveitis, 90 patients (19%) had intermediate uveitis, 100 patients (21%) had posterior uveitis, and 31 patients (7%) had panuveitis. Fifty-six percent of the patients had bilateral involvement, predominantly in intermediate uveitis (ratio 4:1) and panuveitis (ratio 3.4:1). Regarding the etiology of all uveitis cases we found 17% infectious, 23% specific clinical entities, 20% associated with systemic disease (most commonly sarcoidosis with 11%), and 41% idiopathic uveitis.
  
  
  CONCLUSIONS
  Anterior uveitis was the most common anatomic site of intraocular inflammation. Using a tailored approach, screening for systemic etiologies is recommended, since 20% of all patients had associated systemic diseases.
authors.affiliation: a Department of Ophthalmology.
authors.forename: Rafael S
authors.initials: RS
authors.lastname: Grajewski
authors.affiliation: a Department of Ophthalmology.
authors.forename: Albert
authors.initials: A
authors.lastname: Caramoy
authors.affiliation: b Department of Internal Medicine III , and.
authors.forename: Konrad F
authors.initials: KF
authors.lastname: Frank
authors.affiliation: c Department of Internal Medicine I , University of Cologne , Cologne , Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Rubbert-Roth
authors.affiliation: c Department of Internal Medicine I , University of Cologne , Cologne , Germany.
authors.forename: Gerd
authors.initials: G
authors.lastname: Fätkenheuer
authors.affiliation: a Department of Ophthalmology.
authors.forename: Bernd
authors.initials: B
authors.lastname: Kirchhof
authors.affiliation: a Department of Ophthalmology.
authors.forename: Claus
authors.initials: C
authors.lastname: Cursiefen
authors.affiliation: a Department of Ophthalmology.
authors.forename: Ludwig M
authors.initials: LM
authors.lastname: Heindl
keywords: Clinical characteristics; epidemiology; etiology; uveitis