title: EASEPort NPWT System to Enhance Skin Graft Survival--A Simple Assembly.
abstract: Skin graft has been known to be prone to failure. This study was aimed to make a simplification of the negative pressure wound therapy (NPWT), which follows EASEPort (effective, affordable, safe, easily handled, and portable) concept to support the take of skin graft. The design of the EASEPort-NPWT was then made and technically verified. Thereafter, an animal experimental study comparing the EASEPort-NPWT to the classic tie-over technique on skin graft over exudative wound was conducted. The EASEPort-NPWT was verified to be able to yield and sustain the subatmospheric pressure needed. In the animal study, the treatment group showed better skin graft survival rate (97.55 ± 11.18% take) than the control group (54.88 ± 19.73%) on day-7. Histopathology examination showed good quality of the skin structures taken from the treatment group, which was better than the structures of the skin in the control group. In summary, this study has been able to fulfill its objective to create a device following EASEPort concept. Subsequently, the EASEPort-NPWT was able to enhance skin graft survival rate in exudative wound.
authors.affiliation: 1 Division of Plastic Surgery, Department of Surgery, Cipto Mangunkusumo Hospital/Faculty of Medicine University of Indonesia, Jakarta, Indonesia.
authors.forename: Theddeus O H
authors.initials: TO
authors.lastname: Prasetyono
authors.forename: Irena Sakura
authors.initials: IS
authors.lastname: Rini
authors.forename: Cindy
authors.initials: C
authors.lastname: Wibisono
mesh_terms: D000818:Animals; D006085:Graft Survival; D054843:Negative-Pressure Wound Therapy / Q000295:instrumentation* / Q000379:methods; D017063:Outcome Assessment, Health Care; D011182:Postoperative Care / Q000295:instrumentation* / Q000379:methods; D011897:Random Allocation; D016038:Skin Transplantation; D013552:Swine
keywords: Bandages; Exudate and transudate; Foreign body; Skin transplantation; Wound healing