title: [Therapy of bone marrow edema syndrome in the knee with denosumab. Case report].
abstract: BACKGROUND
  The bone marrow edema syndrome (BMES) is a painful joint disease which usually affects healthy middle aged persons. It is usually treated conservatively.
  
  
  OBJECTIVE
  This case report describes the clinical history of a patient with BMES and a therapy attempt with denosumab.
  
  
  CONCLUSIONS
  Complete restitution of the bone marrow edema in the knee and the disappearance of clinical complaints were observed 8 weeks after a single therapy with 60 mg denosumab (Prolia®) as a subcutaneous injection. No side-effects of the therapy were noted.
authors.affiliation: Institut für Klinische Radiologie, Klinikum der Ludwig-Maximilians-Universität München, Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland, tobias.geith@med.uni-muenchen.de.
authors.forename: T
authors.initials: T
authors.lastname: Geith
authors.forename: W
authors.initials: W
authors.lastname: Mutschler
authors.forename: F
authors.initials: F
authors.lastname: Berger
mesh_terms: D018771:Arthralgia / Q000175:diagnosis / Q000517:prevention & control*; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D001855:Bone Marrow Diseases / Q000175:diagnosis* / Q000188:drug therapy*; D000069448:Denosumab / Q000627:therapeutic use*; D004487:Edema / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D007719:Knee Joint / Q000187:drug effects / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D050071:Bone Density Conservation Agents; D000069448:Denosumab