title: POEMS Syndrome Complicated by Extensive Calciphylaxis: A Remarkable Recovery.
abstract: OBJECTIVE
  Calciphylaxis is life threatening. It has traditionally been associated with end-stage renal disease and hyperparathyroidism but is increasingly common in other clinical contexts. The association of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome and calciphylaxis has been reported only in a few cases. This case is the first of patient survival in such widespread disease.
  
  
  RESULTS
  A 42-year-old man with POEMS syndrome developed extensive calciphylaxis despite normal renal and parathyroid function. Rapid diagnosis, treatment, and supportive care contributed to full clinical resolution.
  
  
  CONCLUSIONS
  This is the fifth case of POEMS syndrome associated with calciphylaxis. The observations from this report suggest that POEMS syndrome might be an independent risk factor for the development of calciphylaxis. This case underlines the importance of careful follow-up in patients with POEMS syndrome and prompt diagnosis and treatment of associated calciphylaxis.
authors.forename: Emilie
authors.initials: E
authors.lastname: Bourgeault
authors.forename: Alice
authors.initials: A
authors.lastname: Dahl
authors.forename: Marie-Marthe
authors.initials: MM
authors.lastname: Thibeault
authors.forename: Audrey
authors.initials: A
authors.lastname: Dupéré
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Drolet
authors.forename: Jean
authors.initials: J
authors.lastname: Mathieu
mesh_terms: D000328:Adult; D002115:Calciphylaxis / Q000150:complications*; D006801:Humans; D008297:Male; D016878:POEMS Syndrome / Q000150:complications*