title: A new technology for applanation free corneal trephination: the picosecond infrared laser (PIRL).
abstract: The impact of using a Femtosecond laser on final functional results of penetrating keratoplasty is low. The corneal incisions presented here result from laser ablations with ultrafast desorption by impulsive vibrational excitation (DIVE). The results of the current study are based on the first proof-of-principle experiments using a mobile, newly introduced picosecond infrared laser system, and indicate that wavelengths in the mid-infrared range centered at 3 μm are efficient for obtaining applanation-free deep cuts on porcine corneas.
authors.affiliation: Department of Ophthalmology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany; CareVision/Clinica Baviera Germany and Austria, Martinistrasse 52, 20246, Hamburg, Germany.
authors.forename: Stephan J
authors.initials: SJ
authors.lastname: Linke
authors.affiliation: Department of Ophthalmology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Frings
authors.affiliation: Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761, Hamburg, Germany.
authors.forename: Ling
authors.initials: L
authors.lastname: Ren
authors.affiliation: Department of Ophthalmology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.
authors.forename: Amadeus
authors.initials: A
authors.lastname: Gomolka
authors.affiliation: Department of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.
authors.forename: Udo
authors.initials: U
authors.lastname: Schumacher
authors.affiliation: Heinrich Pette Institute, Leibniz Institute for Experimental Virology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.
authors.forename: Rudolph
authors.initials: R
authors.lastname: Reimer
authors.affiliation: Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761, Hamburg, Germany.
authors.forename: Nils-Owe
authors.initials: NO
authors.lastname: Hansen
authors.affiliation: Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761, Hamburg, Germany; Department of Otorhinolaryngology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.
authors.forename: Nathan
authors.initials: N
authors.lastname: Jowett
authors.affiliation: Department of Ophthalmology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.
authors.forename: Gisbert
authors.initials: G
authors.lastname: Richard
authors.affiliation: Max Planck Institute for the Structure and Dynamics of Matter, Luruper Chaussee 149, 22761, Hamburg, Germany.
authors.forename: R J Dwayne
authors.initials: RJ
authors.lastname: Miller
mesh_terms: D000818:Animals; D003315:Cornea / Q000601:surgery*; D015948:Keratoplasty, Penetrating / Q000295:instrumentation / Q000379:methods; D053685:Laser Therapy / Q000295:instrumentation / Q000379:methods; D013552:Swine