title: [Compliance to treatment and effectiveness of therapy in different regimes of monitoring activity of patients with axial spondyloarthritis].
abstract: OBJECTIVE
  To study compliance to treatment and effectiveness of therapy in patients with axial spondyloarthritis (ax-SpA) in different observational regimes.
  
  
  METHODS
  168 patients without TNF-α therapy and BASDAI ≥ 4 were randomized into 3 groups. 96 of them were observed in a traditional manner, 26 visited a rheumatologist every 12 weeks, and 46 were counseled by phone once in 4 weeks. In all these cases, rheumatologists collected data on the activity of the disease (BASDAI, ASDAS, PASS, etc.) and the effectiveness of therapy.
  
  
  RESULTS
  BASDAI in group 1 was 5.32 ± 3.2 initially and 5.17 ± 2.16 one year after onset of the study, ASDAS 3.45 ± 2.1 and 3.1 ± 1.1 respectively (p > 0.05). In group 2, BASDAI values were 5.21 ± 3.0 and 4.77 ± 2.2; ASDAS 3.42 ± 2.9 and 2.79 ± 2.6 respectively. In group 3, BASDAI values were 5.32 ± 3.2 and 3.17 ± 2.12; ASDAS 3.44 ± 3.1 and 2.6 ± 1.8; p < 0.05 for the differences between initial and subsequent values in groups 2 and 3 and final values for all groups. Positive PASS was reached in 15 patients (57.69%, n = 26) of group 3, in 4 ones (20%, n = 20) of group 2, and in 0 (0%) patients of group 1. Five (19.23%), 15 (75%) and 93 (96.87%) patients in groups 1, 2 and 3 respectively wilfully ceased to take NSAID. 96 (100%), 19 (95%) and 3 (11.5%) patients of these groups stated that they needed hospitalization.
  
  
  CONCLUSIONS
  Telephone monitoring of ax-SpA activity once in every 4 weeks revealed a better compliance with the treatment and results of therapy than active observation every 12 weeks or arbitrary monitoring.
authors.forename: I Z
authors.initials: IZ
authors.lastname: Gaĭdukova
authors.forename: A I
authors.initials: AI
authors.lastname: Akulova
authors.forename: A V
authors.initials: AV
authors.lastname: Aparkina
authors.forename: A P
authors.initials: AP
authors.lastname: Rebrov
mesh_terms: D000328:Adult; D000553:Ambulatory Care / Q000706:statistics & numerical data; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D019468:Disease Management; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D062072:Patient Acuity; D010349:Patient Compliance / Q000523:psychology*; D010817:Physician-Patient Relations; D019114:Remote Consultation / Q000379:methods / Q000706:statistics & numerical data; D025241:Spondylarthritis / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal