title: Neurodevelopment in children with intrauterine growth restriction: adverse effects and interventions.
abstract: Intrauterine growth restriction (IUGR) is associated with higher rates of fetal, perinatal, and neonatal morbidity and mortality. The consequences of IUGR include short-term metabolic, hematological and thermal disturbances that lead to metabolic syndrome in children and adults. Additionally, IUGR severely affects short- and long-term fetal brain development and brain function (including motor, cognitive and executive function) and neurobehavior, especially neuropsychology. This review details the adverse effects of IUGR on fetal brain development and discusses intervention strategies.
authors.affiliation: a Department of Neonatology and NICU , Bayi Children's Hospital, Beijing Military General Hospital , Beijing , China and.|b Department of Neonatology and NICU , Taian City Central Hospital of Shandong Province , Taian City , China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: a Department of Neonatology and NICU , Bayi Children's Hospital, Beijing Military General Hospital , Beijing , China and.
authors.forename: Wei
authors.initials: W
authors.lastname: Fu
authors.affiliation: a Department of Neonatology and NICU , Bayi Children's Hospital, Beijing Military General Hospital , Beijing , China and.
authors.forename: Jing
authors.initials: J
authors.lastname: Liu
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use; D001921:Brain / Q000196:embryology / Q000378:metabolism; D002547:Cerebral Palsy / Q000209:etiology; D002648:Child; D003072:Cognition Disorders / Q000209:etiology / Q000534:rehabilitation; D003863:Depression / Q000209:etiology; D002658:Developmental Disabilities / Q000209:etiology*; D005260:Female; D005317:Fetal Growth Retardation; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007859:Learning Disabilities / Q000209:etiology / Q000534:rehabilitation; D008550:Melatonin / Q000627:therapeutic use; D011181:Postnatal Care; D011247:Pregnancy; D011295:Prenatal Care; D011297:Prenatal Exposure Delayed Effects; D013654:Taurine / Q000627:therapeutic use
chemical_list: D000975:Antioxidants; D013654:Taurine; D008550:Melatonin
keywords: Adverse effects; interventions; intrauterine growth restriction; neurodevelopment