title: [End stage renal disease and ventricular arrhythmia. Hemodialysis and hemodiafiltration differently affect ventricular repolarization].
abstract: Various factors (hypertension [27%], diabetes mellitus [40%]) and their cardiovascular complications play an important role in the genesis of end stage renal disease. Furthermore, primary kidney diseases (glomerulonephritis, tubulointerstitial nephritis, obstructive uropathy, analgesic nephropathy, polycystic kidney disease, autoimmune diseases) have an unfavorable effect on the cardiovascular outcome of this particular population. Increased susceptibility for arrhythmias may be caused by intermittent volume overload, metabolic disturbance, renal anemia, structural and electrophysiological changes of the myocardium, inflammatory mechanisms that may worsen the mortality statistics of these patients. A novel renal replacement method, hemodiafiltration - based on a convective transport - ensures reduced mortality that may be attributed to a decreased occurrence of arrhythmias. The aim of this paper is to review the pathogenetic factors taking part in the arrhythmogenesis of end stage renal disease and to provide diagnostic and therapeutic opportunities that can help in the prediction and prevention of arrhythmias.
authors.affiliation: Debreceni Egyetem, Klinikai Központ Belgyógyászati Intézet Debrecen Nagyerdei krt. 98. 4032.
authors.forename: Árpád
authors.initials: Á
authors.lastname: Czifra
authors.affiliation: Debreceni Egyetem, Klinikai Központ Belgyógyászati Intézet Debrecen Nagyerdei krt. 98. 4032.
authors.forename: Alida
authors.initials: A
authors.lastname: Páll
authors.affiliation: Debreceni Egyetem, Klinikai Központ Belgyógyászati Intézet Debrecen Nagyerdei krt. 98. 4032.
authors.forename: Veronika
authors.initials: V
authors.lastname: Sebestyén
authors.affiliation: Debreceni Egyetem, Klinikai Központ Belgyógyászati Intézet Debrecen Nagyerdei krt. 98. 4032.
authors.forename: Kitti
authors.initials: K
authors.lastname: Barta
authors.affiliation: Debreceni Egyetem, Klinikai Központ Belgyógyászati Intézet Debrecen Nagyerdei krt. 98. 4032.
authors.forename: István
authors.initials: I
authors.lastname: Lőrincz
authors.affiliation: Debreceni Egyetem, Klinikai Központ Belgyógyászati Intézet Debrecen Nagyerdei krt. 98. 4032.
authors.forename: József
authors.initials: J
authors.lastname: Balla
authors.affiliation: Debreceni Egyetem, Klinikai Központ Belgyógyászati Intézet Debrecen Nagyerdei krt. 98. 4032.
authors.forename: György
authors.initials: G
authors.lastname: Paragh
authors.affiliation: Debreceni Egyetem, Klinikai Központ Belgyógyászati Intézet Debrecen Nagyerdei krt. 98. 4032.
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Szabó
mesh_terms: D001145:Arrhythmias, Cardiac / Q000401:mortality / Q000503:physiopathology*; D004452:Echocardiography; D004562:Electrocardiography; D006329:Heart Conduction System / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology*; D017583:Hemodiafiltration; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D006435:Renal Dialysis
keywords: arrhythmia; hemodiafiltration; hemodiafiltráció; hemodialysis; hemodialízis; renal failure; ritmuszavar; veseelégtelenség