title: Natriuretic Peptides as a Novel Target in Resistant Hypertension.
abstract: Resistant hypertension is defined as blood pressure not under goal despite being on at least three antihypertensives. Resistant hypertension is associated with significant cardiovascular morbidity and mortality. Currently, the mainstay for the treatment of resistant hypertension is lifestyle modification and antihypertensive drugs. Natriuretic peptides play an important role in regulating cardiovascular hemodynamics and sodium and fluid homeostasis including blood pressure control. They hold a promising potential for treatment of resistant hypertension.
authors.affiliation: Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
authors.forename: Pratik
authors.initials: P
authors.lastname: Patel
authors.forename: Horng H
authors.initials: HH
authors.lastname: Chen
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D006706:Homeostasis; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000473:pathology; D045265:Natriuretic Peptides / Q000627:therapeutic use*; D011379:Prognosis; D012307:Risk Factors
chemical_list: D000959:Antihypertensive Agents; D045265:Natriuretic Peptides