title: Alkali burn treated with 2% rebamipide ophthalmic suspension: a case report.
abstract: A 47-year-old man presented at the Ophthalmology Department of Saku City Asama General Hospital complaining of hyperemia and pain after industrial sodium hydroxide (approx. 40% concentration) had entered his left eye. With an epithelial defect of the bulbar and palpebral conjunctiva, ischemia of the inferior third of the limbal conjunctiva, a total corneal epithelial defect and mild corneal stromal opacity, the damage was determined as Roper-Hall grade III. 2% rebamipide ophthalmic suspension, which is used for dry eye disease, was administered 4 times a day followed by conventional treatment for serious alkali injury. The corneal epithelial defect was resolved, and there were no side effects. The effectiveness of 2% rebamipide ophthalmic suspension in both the repair and improvement of the damage in the conjunctival and corneal epithelia, and its anti-inflammatory effect suggest that it may be an effective treatment not only for dry eye disease but also for alkali ocular damage.
authors.affiliation: Department of Ophthalmology, Asama General Hospital, Saku, Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Sasaki
authors.affiliation: Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan.
authors.forename: Takamichi
authors.initials: T
authors.lastname: Kokubun
keywords: 2% rebamipide ophthalmic suspension; Alkali burn; Roper-Hall classification