title: Rh/Cu-catalyzed multiple C-H, C-C, and C-N bond cleavage: facile synthesis of pyrido[2,1-a]indoles from 1-(pyridin-2-yl)-1H-indoles and γ-substituted propargyl alcohols.
abstract: An unusual Rh/Cu-catalyzed synthesis of pyrido[2,1-a]indoles starting from 1-(pyridin-2-yl)-1H-indoles and γ-substituted propargyl alcohols was presented. The multi-step cascade transformations formally involve the cleavage of two C-H, three C-C, and one C-N bonds with concomitant construction of two C-H, four C-C, and one C-N bonds with excellent chemoselectivity in one-pot reaction.
authors.affiliation: Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, Fujian, P. R. China. chwtb@xmu.edu.cn.
authors.forename: Ting
authors.initials: T
authors.lastname: Li
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
authors.forename: Mingliang
authors.initials: M
authors.lastname: Zhang
authors.forename: Hui-Jun
authors.initials: HJ
authors.lastname: Zhang
authors.forename: Ting-Bin
authors.initials: TB
authors.lastname: Wen