title: [Intracranial hypertension and jugular vein thrombosis].
abstract: BACKGROUND
  Pseudotumor cerebri is an idiopathic increase in intracranial pressure, which commonly affects obese women of fertile age. The diagnostic criteria according to the guidelines of the German Society for Neurology are increased cerebrospinal fluid (CSF) pressure, symptoms of increased CSF pressure, normal results of CSF examination, no relevant medication and a lack of structural and vascular lesions in magnetic resonance imaging (MRI).
  
  
  METHODS
  This article presents the case of a 39-year-old male patient who presented at hospital with visual obscuration and recently occurred double vision. Except for a recently diagnosed thrombosis of the left jugular vein of unknown origin, there was nothing else of note in the medical history. Biomicroscopic examination showed papilledema with hemorrhages and cotton wool spots. The CSF opening pressure was initially > 50 cmH2O. During therapy by lumbar puncture (three times), oral carbonic anhydrase inhibitors and loop diuretics, the abducens nerve palsy and papilledema receded. Anticoagulation therapy (initially with coumarin derivatives, then with low molecular weight heparins) was unsuccessful in eliminating the thrombosis of the jugular vein. Surgical intervention was not recommended by the vascular surgeons.
  
  
  CONCLUSIONS
  This case report demonstrates the unusual combination of (idiopathic) intracranial hypertension and thrombosis of the jugular vein, which occurred spontaneously and without any detectable coagulation disorders.
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland. juliakonrad1@gmx.de.
authors.forename: J
authors.initials: J
authors.lastname: Konrad
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.
authors.forename: R
authors.initials: R
authors.lastname: Vogt
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Helbig
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland.
authors.forename: I
authors.initials: I
authors.lastname: Oberacher-Velten
mesh_terms: D000086:Acetazolamide / Q000008:administration & dosage; D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage; D002257:Carbonic Anhydrase Inhibitors / Q000008:administration & dosage; D003374:Coumarins / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004172:Diplopia / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007601:Jugular Veins / Q000187:drug effects / Q000473:pathology*; D008297:Male; D009901:Optic Nerve Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D011559:Pseudotumor Cerebri / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D000925:Anticoagulants; D002257:Carbonic Anhydrase Inhibitors; D003374:Coumarins; C030123:coumarin; D000086:Acetazolamide
keywords: Intracranial hypertension; Lumbar puncture; Papilloedema; Risk factors; Thrombosis of the jugular vein