title: EEG correlates of impaired self-other integration during joint-task performance in schizophrenia.
abstract: Deficits in a wide variety of social cognitive processes are well established in schizophrenia. However, research focusing on actual interacting individuals is surprisingly scarce. Problems in low-level processes such as self-other integration may importantly underlie often-reported higher-level deficits. The current study aimed at measuring possible disturbances in self-other integration in schizophrenia using both behavioral and event-related potential (ERP) measures. Sixteen healthy controls and fifteen schizophrenia patients performed a social Simon task in both a joint and an individual setting. Behaviorally, patients showed general slower reaction times, but comparable self-other integration as reflected in the social Simon effect. The ERP results for the healthy controls revealed increased no-go P3 amplitudes in the joint compared with the individual setting. Crucially, patients did not show this increase in no-go P3 amplitude. In line with previous research, the present ERP findings demonstrate that healthy volunteers needed more effort to inhibit their responses in the joint compared with the individual setting. Patients however, showed altered self-other integration when they had to withhold their responses while their co-actor had to act. These outcomes indicate that schizophrenia patients have deficits in low-level processes required for successful joint action.
authors.affiliation: Collaborative Antwerp Psychiatric Research Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium, F.Javier83@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: de la Asuncion
authors.affiliation: Collaborative Antwerp Psychiatric Research Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium, University Psychiatric Center KULeuven, Campus Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Bervoets
authors.affiliation: Collaborative Antwerp Psychiatric Research Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium, Psychiatric Center Brothers Alexians, Provinciesteenweg 408, 2530 Boechout, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Morrens
authors.affiliation: Collaborative Antwerp Psychiatric Research Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium, University Psychiatric Center St Norbertushuis, Stationstraat 22c, 2570 Duffel, Belgium, and.
authors.forename: B
authors.initials: B
authors.lastname: Sabbe
authors.affiliation: Collaborative Antwerp Psychiatric Research Institute, Faculty of Medicine and Health Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium, Department of Clinical Psychology, Leiden Institute for Brain and Cognition (LIBC), Leiden University, Wassenaarseweg 52, 2333 AK Leiden, The Netherlands.
authors.forename: E R A
authors.initials: ER
authors.lastname: De Bruijn
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D004569:Electroencephalography; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D008875:Middle Aged; D011930:Reaction Time; D012559:Schizophrenia / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D013647:Task Performance and Analysis; D055815:Young Adult
keywords: P3 ERP; joint action; schizophrenia; self-other integration; social Simon effect