title: A single-center experience and review of the literature: 64 cases of phyllodes tumors to better understand risk factors and disease management.
abstract: Phyllodes tumors of the breast are rare fibroepithelial tumors that are characterized as benign, borderline, or malignant based on cellular characteristics such as stromal overgrowth and number of mitoses. Currently, there is a lack of consensus on risk factors and management of patients with phyllodes tumors, which has led to variation in treatment patterns as well as patient outcomes across many institutions. This study seeks to understand the clinicopathologic features, risk factors for local and metastatic recurrence, and clinical outcomes of patients with phyllodes tumors to better define optimal treatment patterns.
authors.affiliation: Department of Surgery, University of California at Los Angeles, Los Angeles, California, USA.
authors.forename: Amy L
authors.initials: AL
authors.lastname: Lightner
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Shurell
authors.forename: Nicole
authors.initials: N
authors.lastname: Dawson
authors.forename: Yasaman
authors.initials: Y
authors.lastname: Omidvar
authors.forename: Nova
authors.initials: N
authors.lastname: Foster
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000209:etiology / Q000473:pathology* / Q000628:therapy*; D019468:Disease Management; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D003557:Phyllodes Tumor / Q000209:etiology / Q000473:pathology* / Q000628:therapy*; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult