title: Periodontal regeneration in deep intrabony periodontal defect using hydroxyapatite particles with platelet rich fibrin membrane-a case report.
abstract: BACKGROUND
  Growth factors such as platelet-derived growth factors exert potent effect on wound healing including the regeneration of periodontium. Platelet-rich fibrin (PRF) membrane provides a concentrate of such growth factors, accelerating the wound healing process.
  
  
  METHODS
  In this case report, regeneration of the deep periodontal intrabony defect was attempted using hydroxyapatite particles mixed in the PRF membrane to assess if regeneration of new bone is possible.
  
  
  CONCLUSIONS
  This resulted in a rapid and complete healing with the decrease in the pocket depth and a gain in the clinical attachment level. Rapid regeneration of the periodontium can be achieved with bone substitutes by incorporating the various growth factors from autogenous blood.
authors.affiliation: Assistant Professor, Department of Periodontics, Faculty of Dental Sciences, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
authors.forename: Pavitra
authors.initials: P
authors.lastname: Rastogi
authors.affiliation: Postgraduate Student, Department of Periodontics, Faculty of Dental Sciences, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
authors.forename: Himani
authors.initials: H
authors.lastname: Saini
authors.affiliation: Lecturer, Department of Periodontics, Faculty of Dental Sciences, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
authors.forename: Rameshwari
authors.initials: R
authors.lastname: Singhal
authors.affiliation: Professor and Head, Department of Periodontics, Faculty of Dental Sciences, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
authors.forename: Jaya
authors.initials: J
authors.lastname: Dixit
keywords: Bone substitutes; growth factors; hydroxyapatite; periodontal regeneration; platelet-rich fibrin membrane