title: Pemphigus vulgaris presenting with multiple lesion morphologies.
abstract: Pemphigus vulgaris is an uncommon intraepidermal blistering disorder that typically presents with flaccid bullae or erosions. We report a patient with pemphigus vulgaris who presented with several unusual clinical features: tense bullae with dependently layered pus, true target lesions coalescing into annular configurations, and diffuse desquamation that initially raised concern for toxic epidermal necrolysis. We discuss the differential diagnosis and implications of these morphological findings.
authors.affiliation: Department of Dermatology, Massachusetts General Hospital.
authors.forename: Philip In
authors.initials: PI
authors.lastname: Song
authors.forename: Sherrie J
authors.initials: SJ
authors.lastname: Divito
authors.forename: Daniela
authors.initials: D
authors.lastname: Kroshinsky
mesh_terms: D017668:Age of Onset; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008775:Methylprednisolone / Q000627:therapeutic use; D009173:Mycophenolic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010392:Pemphigus / Q000188:drug therapy / Q000473:pathology*
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid; D008775:Methylprednisolone