title: A Prebiotic Chemistry Experiment on the Adsorption of Nucleic Acids Bases onto a Natural Zeolite.
abstract: There are currently few mechanisms that can explain how nucleic acid bases were synthesized, concentrated from dilute solutions, and/or protected against degradation by UV radiation or hydrolysis on the prebiotic Earth. A natural zeolite exhibited the potential to adsorb adenine, cytosine, thymine, and uracil over a range of pH, with greater adsorption of adenine and cytosine at acidic pH. Adsorption of all nucleic acid bases was decreased in artificial seawater compared to water, likely due to cation complexation. Furthermore, adsorption of adenine appeared to protect natural zeolite from thermal degradation. The C=O groups from thymine, cytosine and uracil appeared to assist the dissolution of the mineral while the NH2 group from adenine had no effect. As shown by FT-IR spectroscopy, adenine interacted with a natural zeolite through the NH2 group, and cytosine through the C=O group. A pseudo-second-order model best described the kinetics of adenine adsorption, which occurred faster in artificial seawaters.
authors.affiliation: Laboratório de Química Prebiótica, Departamento de Química-CCE, Universidade Estadual de Londrina, 86051-990, Londrina, PR, Brazil.
authors.forename: Pedro R
authors.initials: PR
authors.lastname: Anizelli
authors.forename: João Paulo T
authors.initials: JP
authors.lastname: Baú
authors.forename: Frederico P
authors.initials: FP
authors.lastname: Gomes
authors.forename: Antonio Carlos S
authors.initials: AC
authors.lastname: da Costa
authors.forename: Cristine E A
authors.initials: CE
authors.lastname: Carneiro
authors.forename: Cássia Thaïs B V
authors.initials: CT
authors.lastname: Zaia
authors.forename: Dimas A M
authors.initials: DA
authors.lastname: Zaia
mesh_terms: D000327:Adsorption; D019418:Evolution, Chemical; D006863:Hydrogen-Ion Concentration; D009696:Nucleic Acids / Q000737:chemistry*; D012623:Seawater / Q000737:chemistry; D017641:Zeolites / Q000737:chemistry*
chemical_list: D009696:Nucleic Acids; D017641:Zeolites