title: Sarcomatoid (spindle cell) carcinoma of tongue: a report of two cases.
abstract: Sarcomatoid Carcinoma (SC) is an unusual and aggressive variant of squamous cell carcinoma, which frequently recurs and metastasizes; for this reason, the right diagnosis is very important. It is considered to be a biphasic tumor made up of cells from squamous and spindle cells carcinoma with a sarcomatous aspect, but of epithelial origin. The diagnosis often represents a clinical-pathological challenge where the study with immunohistochemical technique (IHC) is key to the histopathological diagnosis. The reported cases related to oral mucosa are limited. In this work we present two SC cases where the use of IHC allowed us to achieve a conclusive diagnosis.
authors.affiliation: Department of Pathology and Oral Medicine, Faculty of Dentistry, University of Chile, Sergio Livingstone Pohlhammer 943, Independencia, 8380492 Santiago, Chile.
authors.forename: Montserrat
authors.initials: M
authors.lastname: Reyes
authors.affiliation: Department of Pathology and Oral Medicine, Faculty of Dentistry, University of Chile, Sergio Livingstone Pohlhammer 943, Independencia, 8380492 Santiago, Chile.
authors.forename: Gina
authors.initials: G
authors.lastname: Pennacchiotti
authors.affiliation: National Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, Chile.
authors.forename: Fabio
authors.initials: F
authors.lastname: Valdes
authors.affiliation: National Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, Chile.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Montes
authors.affiliation: National Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, Chile.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Veloso
authors.affiliation: National Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, Chile.
authors.forename: Maria Angélica
authors.initials: MA
authors.lastname: Matamala
authors.affiliation: National Cancer Institute, Profesor Zañartu 1010, Independencia, 8380492 Santiago, Chile.
authors.forename: Luis
authors.initials: L
authors.lastname: Zanolli
authors.affiliation: Department of Pathology and Oral Medicine, Faculty of Dentistry, University of Chile, Sergio Livingstone Pohlhammer 943, Independencia, 8380492 Santiago, Chile.
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Rojas-Alcayaga