title: The plasma and platelet are important in reducing the mortality in surgical massive blood transfusion: a large multicenter study in China.
abstract: OBJECTIVE
  The aim of this study was to learn the current situation of surgical massive transfusion of death and survival groups in China, which could provide the basis for the formulation of guidelines on massive transfusion.
  
  
  METHODS
  A multicenter retrospective research for the application status of blood constituents during massive blood transfusion was conducted, the differences of fresh frozen plasma and platelet application between death group and survival group were compared, and the transfusion volume and the distribution of other blood constituents were analyses at different periods of time when red blood cells are infused between death group and survival group.
  
  
  RESULTS
  The patients with fresh frozen plasma compare the patients with red blood cell was 1:1-2 during massive transfusion, while the dosage of platelet and cryocepitate were transfused very small. Results showed that the average amount of platelet and plasma in death group was significantly lower than those in survival group.
  
  
  CONCLUSIONS
  During massive transfusion, clinicians in 20 Chinese hospitals paid more attention to the infusion of fresh frozen plasma while making the infusion of red blood cells. However, they paid little attention to the supplement of platelet and cryocepitate. The average quantity of plasma and platelet in survival group were also higher than those in death group.
authors.affiliation: The Second Department of Orthopaedics, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
authors.forename: Zhan-Kui
authors.initials: ZK
authors.lastname: Jin
authors.affiliation: Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Sun
authors.affiliation: Department of Dermatology, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
authors.forename: Qian-Li
authors.initials: QL
authors.lastname: Dang
authors.affiliation: Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
authors.forename: Li-Jie
authors.initials: LJ
authors.lastname: Zhang
authors.affiliation: Department of Laboratory, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Urology, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
authors.forename: Yong-Gang
authors.initials: YG
authors.lastname: Xu
authors.affiliation: Department of Laboratory, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
authors.forename: Hong-Nan
authors.initials: HN
authors.lastname: Chen
authors.affiliation: Department of Shaanxi Provincial Center for Clinical Laboratory, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
authors.forename: Cui-Xiang
authors.initials: CX
authors.lastname: Xu
authors.affiliation: Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
authors.forename: Yao-Jun
authors.initials: YJ
authors.lastname: Song
authors.affiliation: Department of Transfusion Medicine, The Third Affiliated Hospital of Medical College of Xi'an Jiaotong University Xi'an, China.
authors.forename: Jiang-Cun
authors.initials: JC
authors.lastname: Yang
keywords: Massive transfusion; blood constituents; plasma; platelet