title: [Establishment of prescription research technology system in Chinese medicine secondary exploitation based on "component structure" theory].
abstract: Chinese medicine prescriptions are the wisdom outcomes of traditional Chinese medicine (TCM) clinical treatment determinations which based on differentiation of symptoms and signs. Chinese medicine prescriptions are also the basis of secondary exploitation of TCM. The study on prescription helps to understand the material basis of its efficacy, pharmacological mechanism, which is an important guarantee for the modernization of traditional Chinese medicine. Currently, there is not yet dissertation n the method and technology system of basic research on the prescription of Chinese medicine. This paper focuses on how to build an effective system of prescription research technology. Based on "component structure" theory, a technology system contained four-step method that "prescription analysis, the material basis screening, the material basis of analysis and optimization and verify" was proposed. The technology system analyzes the material basis of the three levels such as Chinese medicine pieces, constituents and the compounds which could respect the overall efficacy of Chinese medicine. Ideas of prescription optimization, remodeling are introduced into the system. The technology system is the combination of the existing research and associates with new techniques and methods, which used for explore the research thought suitable for material basis research and prescription remodeling. The system provides a reference for the secondary development of traditional Chinese medicine, and industrial upgrading.
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Cheng
authors.forename: Liang
authors.initials: L
authors.lastname: Feng
authors.forename: Jun-Fei
authors.initials: JF
authors.lastname: Gu
authors.forename: Ming-Hua
authors.initials: MH
authors.lastname: Zhang
authors.forename: Xiao-Bin
authors.initials: XB
authors.lastname: Jia
mesh_terms: D011307:Drug Prescriptions; D008516:Medicine, Chinese Traditional