title: New paradigms for the chiral synthesis of inositol phosphates.
abstract: Paradigms found: Inositol phosphates are biomolecules found ubiquitously in eukaryotes, in which they play a number of vital biological roles. Their enantioselective synthesis has recently received a boost from two complementary phosphorylation methods that could change the way they are synthesised, and hopefully provide invaluable chemical biology tools to further our understanding of this large family.
authors.affiliation: Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 1-5/10, 8093, Zürich (Switzerland).
authors.forename: Estelle
authors.initials: E
authors.lastname: Durantie
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Leroux
authors.forename: Bastien
authors.initials: B
authors.lastname: Castagner
mesh_terms: D060326:Chemistry Techniques, Synthetic; D007295:Inositol Phosphates / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007295:Inositol Phosphates
keywords: chiral resolution; chiral synthesis; inositol phosphate; organocatalysis; phosphorylation