title: Mitosis, diffusible crosslinkers, and the ideal gas law.
abstract: During mitosis, molecular motors hydrolyze ATP to generate sliding forces between adjacent microtubules and form the bipolar mitotic spindle. Lansky et al. now show that the diffusible microtubule crosslinker Ase1p can generate sliding forces between adjacent microtubules, and it does so without ATP hydrolysis.
authors.affiliation: Department of Biomedical Engineering, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: oddex002@umn.edu.
authors.forename: David J
authors.initials: DJ
authors.lastname: Odde
mesh_terms: D000818:Animals; D008870:Microtubules / Q000378:metabolism*