title: HAESA and HAESA-LIKE2 activate organ abscission downstream of NEVERSHED and EVERSHED in Arabidopsis flowers.
abstract: A ligand-receptor module comprised of the peptide inflorescence deficient in abscission (IDA) and the receptor-like kinases HAESA (HAE) and HAESA-LIKE2 (HSL2) activates organ abscission in Arabidopsis flowers. Another set of receptor-like kinases, including EVERSHED (EVR), restricts the extent of cell separation in abscission zones by potentially altering HAE/HSL2 localization or activity. The NEVERSHED (NEV) ADP-ribosylation factor GTPase-activating protein facilitates the intracellular movement of molecules required for organ abscission and fruit growth. Here we report further analysis of the relationship between NEV-mediated intracellular traffic, EVR activity and IDA-HAE/HSL2 signaling during flower development. Our results support a model in which cell separation is mediated by HAE/HSL2 signaling downstream of NEV and EVR. We discuss the possibility that conserved circuits control organ abscission and modulate fruit growth.
authors.affiliation: a 1Department of Biology; University of Mississippi; Oxford, MS USA.
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Gubert
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Liljegren
mesh_terms: D017360:Arabidopsis / Q000254:growth & development / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D016922:Cellular Senescence; D035264:Flowers / Q000254:growth & development / Q000378:metabolism*; D005638:Fruit / Q000254:growth & development*; D020690:GTPase-Activating Proteins / Q000378:metabolism*; D063245:Plant Development; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; D020690:GTPase-Activating Proteins; C512213:IDA protein, Arabidopsis; C544765:NEV protein, Arabidopsis; C000589322:HSL2 protein, Arabidopsis; C089427:RLK5 protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases
keywords: EVR; HAE; HSL2; IDA; NEV; cell separation; cell signaling; floral organ abscission; fruit development; intracellular traffic