title: Crohn Disease of the Vulva without Gastrointestinal Manifestations in a 16-Year-Old Girl.
abstract: BACKGROUND
  Crohn disease of the vulva is a rare disease that is difficult to diagnose. There are limited reports describing treatment of this condition.
  
  
  OBJECTIVE
  To describe the diagnosis and treatment of a 16-year-old girl with Crohn disease of the vulva, without onset of intestinal symptoms.
  
  
  METHODS
  Crohn disease was diagnosed by histopathology. The patient was treated with corticosteroids and followed for 1 year.
  
  
  RESULTS
  After the final diagnosis, cutaneous lesions responded rapidly to corticosteroid treatment, which was gradually stopped after 6 months. The disease was well controlled at the 1-year follow-up.
  
  
  CONCLUSIONS
  Crohn disease of the vulva can develop alone without the onset of intestinal symptoms. Diagnosis relies on special pathologic findings. Corticosteroid treatment is effective for this condition.
authors.affiliation: Department of Gastroenterology, Qilu Hospital of Shandong University, JinanDepartments of Gastroenterology and Pathology, Qingdao Municipal Hospital, Qingdao, P.R. China.
authors.forename: Ai-jun
authors.initials: AJ
authors.lastname: Zhang
authors.affiliation: Department of Gastroenterology, Qilu Hospital of Shandong University, JinanDepartments of Gastroenterology and Pathology, Qingdao Municipal Hospital, Qingdao, P.R. China.
authors.forename: Shu-hui
authors.initials: SH
authors.lastname: Zhan
authors.affiliation: Department of Gastroenterology, Qilu Hospital of Shandong University, JinanDepartments of Gastroenterology and Pathology, Qingdao Municipal Hospital, Qingdao, P.R. China.
authors.forename: Hong
authors.initials: H
authors.lastname: Chang
authors.affiliation: Department of Gastroenterology, Qilu Hospital of Shandong University, JinanDepartments of Gastroenterology and Pathology, Qingdao Municipal Hospital, Qingdao, P.R. China.
authors.forename: Yu-qiang
authors.initials: YQ
authors.lastname: Gao
authors.affiliation: Department of Gastroenterology, Qilu Hospital of Shandong University, JinanDepartments of Gastroenterology and Pathology, Qingdao Municipal Hospital, Qingdao, P.R. China mx8902@163.com.
authors.forename: Yan-qing
authors.initials: YQ
authors.lastname: Li
mesh_terms: D000293:Adolescent; D003424:Crohn Disease / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D012871:Skin Diseases / Q000188:drug therapy / Q000473:pathology*; D014845:Vulvar Diseases / Q000188:drug therapy / Q000473:pathology*
chemical_list: D008775:Methylprednisolone