title: [Radiological and anatomical approaches to the evaluation of blood circulation and functional state of a cardiopatient].
abstract: Cardiovascular diseases are ranked worldwide as the key factor of morbidity and mortality; they impair the quality of life and cause great losses to state economy. Coronary heart disease is of special significance due to the high prevalence, high risk and frequency of complications. Radiodiagnostics used to examine cardiologic patients makes possible visualization of coronary arteries and evaluation of their morphometric parameters, but it fails to provide information on the changes in hemomicrocirculation and to estimate myocardial perfusion or changes in the structural and functional changes in myocardial tissue and cardiac afferent system. It does not allow to determine severity of cardiac insuffciency resulting in hemodynamic changes at the tissue, organ, and body levels. We are unaware of publications showing correlation between morphofunctional organization ofhemocilculatory system and the functional state of cardiomyocytes. None of the anatomical or clinical-diagnostic criteria of modern radiological methods gives an answer to the question of correlation between myocardial vessel structure and structural-functional state of cardiomyocytes in subjects of different sex and age. To recall, the functional potential of the heart as a whole organ is determined by that of contractile (working, typical) and atypical (conducting) cardiomyocytes responsible for impulse conduction from the pacemaker which implies differential approach to the elucidation of correlations between angioarchitectonics of vessels in different heart regions and functional potential of typical and atypical cardiomyocytes.
authors.forename: V E
authors.initials: VE
authors.lastname: Miliukov
authors.forename: T S
authors.initials: TS
authors.lastname: Zharikova
mesh_terms: D017023:Coronary Angiography / Q000379:methods*; D003326:Coronary Circulation; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D008660:Metabolism; D008833:Microcirculation; D055414:Myocardial Perfusion Imaging / Q000379:methods*; D032383:Myocytes, Cardiac / Q000378:metabolism / Q000473:pathology