title: Focus issue: noncoding RNAs in cancer.
abstract: Through various means, noncoding RNAs regulate the expression of genes, many of which are associated with cellular homeostasis. Noncoding RNAs--especially microRNAs--are critical regulators of the mechanisms underlying numerous processes in cell biology, particularly those involved in the development and progression of cancer. This special issue of Science Signaling sheds light on the physiological and pathophysiological functions of this distinct class of molecules.
authors.affiliation: Associate Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA. lferrare@aaas.org.
authors.forename: Leslie K
authors.initials: LK
authors.lastname: Ferrarelli
mesh_terms: D000818:Animals; D006801:Humans; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism*; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D012334:RNA, Neoplasm / Q000235:genetics / Q000378:metabolism*
chemical_list: D035683:MicroRNAs; D012334:RNA, Neoplasm