title: Involvement of prostaglandin E2 in the first Japanese case of pachydermoperiostosis with HPGD mutation and recalcitrant leg ulcer.
authors.affiliation: Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan; Division of Dermatology, Fujinomiya City Hospital, Fujinomiya, Japan.
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Nakazawa
authors.affiliation: Department of Dermatology, National Center for Child Health and Development, Setagaya-ku, Tokyo, Japan. Electronic address: niizeki-h@ncchd.go.jp.
authors.forename: Hironori
authors.initials: H
authors.lastname: Niizeki
authors.affiliation: Department of Dermatology, National Center for Child Health and Development, Setagaya-ku, Tokyo, Japan.
authors.forename: Maiko
authors.initials: M
authors.lastname: Matsuda
authors.affiliation: Department of Maternal-Fetal Biology, National Research Institute for Child Health and Development, Tokyo, Japan.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nakabayashi
authors.affiliation: Department of Orthopedics, National Center for Child Health and Development, Setagaya-ku, Tokyo, Japan.
authors.forename: Atsuhito
authors.initials: A
authors.lastname: Seki
authors.affiliation: Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan; Division of Dermatology, Fujinomiya City Hospital, Fujinomiya, Japan.
authors.forename: Tatsuyoshi
authors.initials: T
authors.lastname: Mori
authors.affiliation: Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Tokura
mesh_terms: D002908:Chronic Disease; D015232:Dinoprostone / Q000097:blood* / Q000652:urine; D005260:Female; D006801:Humans; D006911:Hydroxyprostaglandin Dehydrogenases / Q000235:genetics; D007564:Japan; D007871:Leg Ulcer / Q000150:complications / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D027361:Organic Anion Transporters / Q000235:genetics; D010004:Osteoarthropathy, Primary Hypertrophic / Q000150:complications / Q000235:genetics* / Q000378:metabolism*; D010375:Pedigree
chemical_list: D027361:Organic Anion Transporters; C503526:SLCO2A1 protein, human; D006911:Hydroxyprostaglandin Dehydrogenases; D015232:Dinoprostone
keywords: HPGD; Primary hypertrophic osteoarthropathy; Prostaglandin E2; Prostaglandin transporter; SLCO2A1