title: Ovarian strumal carcinoid containing appendiceal-type mucinous tumor patterns presenting as pseudomyxoma peritonei.
abstract: We report for the first time a case of ovarian strumal carcinoid containing both trabecular carcinoid and mucinous glands lined by both goblet and neuroendocrine cells and a low-grade mucinous neoplasm that presented clinically as pseudomyxoma peritonei in the absence of appendiceal lesion in a 58-yr-old woman. Histologically, there were both a tall columnar cell epithelial component lacking neuroendocrine cells, showing the scalloped contours and subepithelial clefts of low-grade appendiceal-type neoplasms and a mixed goblet cell neuroendocrine element. Characteristically, both reproduced appendiceal neoplastic phenotypes in a teratoid fashion. In addition, we present previously unreported oncocytic and mucinous changes in the thyroideal components of strumal carcinoid. This case represents a rare instance of pseudomyxoma peritonei of primary ovarian origin and is an example of multiple somatic teratoid endodermal differentiations of the different sections of the embryonal gut: foregut represented by thyroid, midgut by both mucinous appendiceal components, and hindgut by trabecular carcinoid.
authors.affiliation: Department of Pathology, Facultad de Medicina, San Cecilio University of Granada Hospital, Granada, Spain.
authors.forename: Enoe
authors.initials: E
authors.lastname: Quiñonez
authors.forename: Maolly
authors.initials: M
authors.lastname: Schuldt
authors.forename: Juan A
authors.initials: JA
authors.lastname: Retamero
authors.forename: Francisco F
authors.initials: FF
authors.lastname: Nogales
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D002276:Carcinoid Tumor / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology*; D010534:Peritoneal Neoplasms / Q000473:pathology*; D011553:Pseudomyxoma Peritonei / Q000473:pathology*; D013330:Struma Ovarii / Q000473:pathology*