title: Metal nanoparticles reduce bacterial contamination of experimental purulent wounds.
abstract: Bacterial contamination of experimental purulent wound in rats treated by local applications of suspension of copper and zinc nanoparticles and a combined drug based on chitosan and copper and zinc nanoparticles was evaluated. Applications of copper nanoparticle suspension and combined drug with copper and zinc nanoparticles and chitosan led to rapid elimination of the bacterial contaminant. Antibacterial activity of zinc nanoparticles was less pronounced, but the effect also differed significantly from the reference group.
authors.affiliation: Saratov Research Institute of Traumatology and Orthopedics, Ministry of Health of the Russian Federation, Moscow, Russia, 10051968@mail.ru.
authors.forename: I V
authors.initials: IV
authors.lastname: Babushkina
authors.forename: I A
authors.initials: IA
authors.lastname: Mamontova
authors.forename: E V
authors.initials: EV
authors.lastname: Gladkova
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D048271:Chitosan / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry*; D014945:Wound Healing / Q000187:drug effects; D015032:Zinc / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D003300:Copper; D048271:Chitosan; D015032:Zinc