title: Oxygen provision of the brain at various stages of operation in patients with chronic pulmonary artery thromboembolism.
abstract: The authors studied cerebral oxygen supply by means of cerebral oximetry in patients presenting with chronic pulmonary artery thromboembolism (PATE) at various stages of operation. The study was aimed at assessing cerebral oxygen supply while carrying out surgical treatment in patients with chronic PATE on the background of various methods of perfusion. Thromboendarterectomy (TEA) from the pulmonary artery with the use of circulatory arrest and craniocerebral hypothermia is accompanied by more pronounced impairment of oxygen supply of the brain with a decrease in the cerebral oxygenation indices by more than 30% from the baseline values. These alterations promote increased risk for the development of neurological complications in the early postoperative period. Using the technique of antegrade cerebral perfusion ensures a minimum decrease of cerebral oxygenation during TEA and contributes to a reduction of the risk for the development of neurological complications.
authors.affiliation: Novosibirsk Scientific Research Institute of Circulatory Pathology named after Academician E.N. Meshalkin under the RF Ministry of Public Health, Novosibirsk, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Kamenskaia
authors.affiliation: Novosibirsk Scientific Research Institute of Circulatory Pathology named after Academician E.N. Meshalkin under the RF Ministry of Public Health, Novosibirsk, Russia.
authors.forename: A S
authors.initials: AS
authors.lastname: Klinkova
authors.affiliation: Novosibirsk Scientific Research Institute of Circulatory Pathology named after Academician E.N. Meshalkin under the RF Ministry of Public Health, Novosibirsk, Russia.
authors.forename: A M
authors.initials: AM
authors.lastname: Cherniavskiĭ
authors.affiliation: Novosibirsk Scientific Research Institute of Circulatory Pathology named after Academician E.N. Meshalkin under the RF Ministry of Public Health, Novosibirsk, Russia.
authors.forename: M A
authors.initials: MA
authors.lastname: Cherniavskiĭ
authors.affiliation: Novosibirsk Scientific Research Institute of Circulatory Pathology named after Academician E.N. Meshalkin under the RF Ministry of Public Health, Novosibirsk, Russia.
authors.forename: R A
authors.initials: RA
authors.lastname: Kalinin
authors.affiliation: Novosibirsk Scientific Research Institute of Circulatory Pathology named after Academician E.N. Meshalkin under the RF Ministry of Public Health, Novosibirsk, Russia.
authors.forename: A M
authors.initials: AM
authors.lastname: Karas'kov
mesh_terms: D000328:Adult; D001921:Brain / Q000098:blood supply*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002908:Chronic Disease; D004691:Endarterectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D010092:Oximetry; D010100:Oxygen / Q000097:blood*; D011655:Pulmonary Embolism / Q000097:blood* / Q000503:physiopathology / Q000601:surgery
chemical_list: D010100:Oxygen