title: Unilateral acute maculopathy associated with adult onset hand, foot and mouth disease: case report and review of literature.
abstract: BACKGROUND
  Acute maculopathy is a rare condition of unknown aetiology and Coxsackie virus is known to be associated with this macular chorioretinitis.
  
  
  RESULTS
  We report a case of acute unilateral maculopathy in a 35-year-old woman with concurrent hand foot and mouth disease. Furthermore, we display multimodal imaging (colour fundus photographs, autofluorescence, spectral domain ocular coherence tomography, fluorescein angiography and indocyanine green angiography) charting the course of the disease. The source of the virus was thought to be the patient's child. Empirical treatment with oral corticosteroids was commenced and the inflammation resolved, leaving a residual macular scar.
  
  
  CONCLUSIONS
  We present this case combined with the review of literature of adult onset Coxsackie-virus-associated retinitis. This case reiterates the fact that Coxsackie virus is an uncommon but important consideration in the differential diagnosis of chorioretinitis and posterior uveitis with atypical retinopathy.
authors.affiliation: Moorfields Eye Hospital, NHS Foundation Trust, 162 City Road, London, EC1V 2PD UK ; Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, 162 City Road, London, EC1V 2PD UK ; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433 Singapore.
authors.forename: Rupesh
authors.initials: R
authors.lastname: Agrawal
authors.affiliation: Moorfields Eye Hospital, NHS Foundation Trust, 162 City Road, London, EC1V 2PD UK.
authors.forename: Kanchan
authors.initials: K
authors.lastname: Bhan
authors.affiliation: Moorfields Eye Hospital, NHS Foundation Trust, 162 City Road, London, EC1V 2PD UK.
authors.forename: Kam
authors.initials: K
authors.lastname: Balaggan
authors.affiliation: Moorfields Eye Hospital, NHS Foundation Trust, 162 City Road, London, EC1V 2PD UK ; Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, 162 City Road, London, EC1V 2PD UK ; University Hospitals Bristol NHS Foundation Trust, Upper Maudlin Street, Bristol, BS2 8HW UK.
authors.forename: Richard Wj
authors.initials: RW
authors.lastname: Lee
authors.affiliation: Moorfields Eye Hospital, NHS Foundation Trust, 162 City Road, London, EC1V 2PD UK ; Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, 162 City Road, London, EC1V 2PD UK.
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Pavesio
authors.affiliation: Moorfields Eye Hospital, NHS Foundation Trust, 162 City Road, London, EC1V 2PD UK.
authors.forename: Peter Kf
authors.initials: PK
authors.lastname: Addison
keywords: Acute maculopathy; Autofluorescence; Coxsackie virus; Hand; Posterior uveitis; foot and mouth disease (HFMD)