title: New onset of articular inflammatory manifestations in patients with hidradenitis suppurativa under treatment with infliximab.
abstract: OBJECTIVE
  Severe hidradenitis suppurativa (HS), under infliximab, can be associated with different forms of arthritis whose mechanism is unclear. Our objective is to establish the frequency and clinical presentation of new-onset arthritis in HS under infliximab.
  
  
  METHODS
  Severe HS patients under infliximab were followed up between 2007-2012. New articular inflammatory manifestations were investigated by rheumatologist.
  
  
  RESULTS
  Three patients over eleven developed a polyarthritis. Mean duration of arthritis was 3 months. At treatment's stop: 2 patients improved and 1 relieved with adalimumab.
  
  
  CONCLUSIONS
  The inflammatory rheumatism's frequency in HS under infliximab seems underestimated.
authors.affiliation: Department of rheumatology, university hospital of Nice, 151, route de Saint-Antoine-de-Ginestière, 06200 Nice, France. Electronic address: acquacalda.e@chu-nice.fr.
authors.forename: Emilie
authors.initials: E
authors.lastname: Acquacalda
authors.affiliation: Department of rheumatology, university hospital of Nice, 151, route de Saint-Antoine-de-Ginestière, 06200 Nice, France.
authors.forename: Christian Hubert
authors.initials: CH
authors.lastname: Roux
authors.affiliation: Department of rheumatology, university hospital of Nice, 151, route de Saint-Antoine-de-Ginestière, 06200 Nice, France.
authors.forename: Christine
authors.initials: C
authors.lastname: Albert
authors.affiliation: Department of rheumatology, university hospital of Nice, 151, route de Saint-Antoine-de-Ginestière, 06200 Nice, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Breuil
authors.affiliation: Department of dermatology, university hospital of Nice, 06200 Nice, France; Inserm, U1065, centre méditerranéen de médecine moléculaire (C3M), team 12, 06100 Nice, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Passeron
authors.affiliation: Department of rheumatology, university hospital of Nice, 151, route de Saint-Antoine-de-Ginestière, 06200 Nice, France.
authors.forename: Liana
authors.initials: L
authors.lastname: Euller-Ziegler
mesh_terms: D000328:Adult; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001168:Arthritis / Q000175:diagnosis / Q000209:etiology*; D005500:Follow-Up Studies; D017497:Hidradenitis Suppurativa / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D000069285:Infliximab / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008297:Male; D012189:Retrospective Studies
chemical_list: D018501:Antirheumatic Agents; D000069285:Infliximab
keywords: Hidradenitis suppurativa; Infliximab; Paradoxical reaction; Spondyloarthritis