title: The Use of Carbon-Fiber-Reinforced (CFR) PEEK Material in Orthopedic Implants: A Systematic Review.
abstract: Carbon-fiber-reinforced polyetheretherketone (CFR-PEEK) has been successfully used in orthopedic implants. The aim of this systematic review is to investigate the properties, technical data, and safety of CFR-PEEK biomaterial and to evaluate its potential for new innovation in the design of articulating medical devices. A comprehensive search in PubMed and EMBASE was conducted to identify articles relevant to the outcomes of CFR-PEEK orthopedic implants. The search was also expanded by reviewing the reference sections of selected papers and references and benchmark reports provided by content experts. A total of 23 articles were included in this review. There is limited literature available assessing the performance of CFR-PEEK, specifically as an implant material for arthroplasty systems. Nevertheless, available studies strongly support CFR-PEEK as a promising and suitable material for orthopedic implants because of its biocompatibility, material characteristics, and mechanical durability. Future studies should continue to investigate CFR-PEEK's potential benefits.
authors.affiliation: Global Research Solutions, Inc., Burlington, Ontario, Canada. ; Division of Orthopedic Surgery, Centre for Evidence-Based Orthopedics, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Chuan Silvia
authors.initials: CS
authors.lastname: Li
authors.affiliation: Global Research Solutions, Inc., Burlington, Ontario, Canada.
authors.forename: Christopher
authors.initials: C
authors.lastname: Vannabouathong
authors.affiliation: Global Research Solutions, Inc., Burlington, Ontario, Canada. ; Division of Orthopedic Surgery, Centre for Evidence-Based Orthopedics, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Sheila
authors.initials: S
authors.lastname: Sprague
authors.affiliation: Global Research Solutions, Inc., Burlington, Ontario, Canada. ; Division of Orthopedic Surgery, Centre for Evidence-Based Orthopedics, McMaster University, Hamilton, Ontario, Canada.
authors.forename: Mohit
authors.initials: M
authors.lastname: Bhandari
keywords: CFR-PEEK; carbon-fiber-reinforced polyetheretherketone; implants; orthopedics; review