title: Alcohol Use Disorders and Community-Acquired Pneumococcal Pneumonia: Associated Mortality, Prolonged Hospital Stay and Increased Hospital Spending.
abstract: BACKGROUND
  The aim of this study was to investigate the impact of alcohol use disorders (AUD) on community-acquired pneumococcal pneumonia (CAPP) admissions, in terms of in-hospital mortality, prolonged stay and increased hospital spending.
  
  
  METHODS
  Retrospective observational study of a sample of CAPP patients from the minimum basic datasets of 87 Spanish hospitals during 2008-2010. Mortality, length of hospital stay and additional spending attributable to AUD were calculated after multivariate covariance analysis for variables such as age and sex, type of hospital, addictions and comorbidities.
  
  
  RESULTS
  Among 16,202 non-elective admissions for CAPP in patients aged 18-74years, 2,685 had AUD. Patients admitted with CAPP and AUD were predominantly men with a higher prevalence of tobacco or drug use disorders and higher Charlson comorbidity index. Patients with CAPP and AUD had notably higher in-hospital mortality (50.8%; CI95%: 44.3-54.3%), prolonged length of stay (2.3days; CI95%: 2.0-2.7days) and increased costs (1,869.2€; CI95%: 1,498.6-2,239.8€).
  
  
  CONCLUSIONS
  According to the results of this study, AUD in CAPP patients was associated with increased in-hospital mortality, length of hospital stay and hospital spending.
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad de Sevilla, Sevilla, España; Servicio de Medicina Preventiva y Salud Pública, Hospital Universitario Virgen Macarena, Sevilla, España. Electronic address: mgili@us.es.
authors.forename: Miguel
authors.initials: M
authors.lastname: Gili-Miner
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad de Sevilla, Sevilla, España; Servicio de Medicina Preventiva y Salud Pública, Hospital Universitario Virgen Macarena, Sevilla, España.
authors.forename: Julio
authors.initials: J
authors.lastname: López-Méndez
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad de Sevilla, Sevilla, España.
authors.forename: Luis
authors.initials: L
authors.lastname: Béjar-Prado
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad de Sevilla, Sevilla, España; Servicio de Medicina Preventiva y Salud Pública, Hospital Universitario Virgen Macarena, Sevilla, España.
authors.forename: Gloria
authors.initials: G
authors.lastname: Ramírez-Ramírez
authors.affiliation: Departamento de Medicina Preventiva y Salud Pública, Universidad de Sevilla, Sevilla, España; Servicio de Medicina Preventiva y Salud Pública, Hospital Universitario Virgen Macarena, Sevilla, España.
authors.forename: Ángel
authors.initials: Á
authors.lastname: Vilches-Arenas
authors.affiliation: Servicio de Documentación Clínica, Hospital Universitario Virgen Macarena, Sevilla, España.
authors.forename: José
authors.initials: J
authors.lastname: Sala-Turrens
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019973:Alcohol-Related Disorders / Q000191:economics / Q000453:epidemiology*; D017714:Community-Acquired Infections / Q000191:economics / Q000453:epidemiology*; D015897:Comorbidity; D005260:Female; D017721:Hospital Costs / Q000706:statistics & numerical data*; D017052:Hospital Mortality; D006760:Hospitalization / Q000191:economics / Q000706:statistics & numerical data; D006801:Humans; D007902:Length of Stay / Q000191:economics / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D010819:Physician's Role; D022242:Pneumococcal Vaccines; D011018:Pneumonia, Pneumococcal / Q000191:economics / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D064424:Tobacco Use / Q000453:epidemiology
chemical_list: D022242:Pneumococcal Vaccines
keywords: Alcohol use disorders; Costes; Costs; Estancia hospitalaria; Hospital stay; Mortalidad; Mortality; Neumonía neumocócica; Pneumococcal pneumonia; Trastornos asociados al consumo de alcohol