title: Antimicrobial and antioxidant activities and phenolic profile of Eucalyptus globulus Labill. and Corymbia ficifolia (F. Muell.) K.D. Hill & L.A.S. Johnson leaves.
abstract: This study was performed to evaluate the in vitro antimicrobial and antioxidant activities and the phenolic profile of Eucalytus globulus Labill. and Corymbia ficifolia (F. Muell.) K.D. Hill & L.A.S. Johnson leaves. Both leave extracts contain significant amounts of phenolic compounds, mainly flavonoids. Qualitative and quantitative analyses of the phenolic compounds were performed using a HPLC/MS method. The main flavonoid was hyperoside and its highest amount was found in E. globulus (666.42 ± 5.02 μg/g dw plant material). Regarding the flavonol profile, myricetin was the dominant compound and its highest amount was found in C. ficifolia leaves (124.46 ± 0.24 μg/g dw plant material). The antioxidant activity was evaluated by DPPH, TEAC, hemoglobin ascorbate peroxidase activity inhibition (HAPX) and inhibition of lipid peroxidation catalyzed by cytochrome c assays, revealing an important antioxidant potential for both species. In the antimicrobial assays, C. ficifolia extract was found to be more active than E. globulus against both Gram-positive and Gram-negative bacterial strains with the exception of Bacillus subtilis. The results of the present study provide new valuable data regarding the bioactivities of these medicinal species.
authors.affiliation: Faculty of Geography, Babeș-Bolyai University, 5-7, Clinicilor Street, Cluj-Napoca 400006, Romania. stefan@geografie.ubbcluj.ro.
authors.forename: Ștefan
authors.initials: Ș
authors.lastname: Dezsi
authors.affiliation: Faculty of Environmental Sciences and Engineering, Babeș-Bolyai University, 30, Fântânele Street, Cluj-Napoca 400294, Romania. alexandru@transsilvanica.net.
authors.forename: Alexandru Sabin
authors.initials: AS
authors.lastname: Bădărău
authors.affiliation: Faculty of Chemistry and Chemical Engineering, Babeș-Bolyai University, 11, A. Janos Street, Cluj-Napoca 400028, Romania. cristina_bischin@yahoo.com.
authors.forename: Cristina
authors.initials: C
authors.lastname: Bischin
authors.affiliation: Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, 3-5, Manăştur Street, Cluj-Napoca 400372, Romania. dan.vodnar@usamvcluj.ro.
authors.forename: Dan Cristian
authors.initials: DC
authors.lastname: Vodnar
authors.affiliation: Faculty of Chemistry and Chemical Engineering, Babeș-Bolyai University, 11, A. Janos Street, Cluj-Napoca 400028, Romania. rsilaghi@chem.ubbcluj.ro.
authors.forename: Radu
authors.initials: R
authors.lastname: Silaghi-Dumitrescu
authors.affiliation: Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, 8, V. Babes Street, Cluj-Napoca 400010, Romania. Gheldiu.Ana@umfcluj.ro.
authors.forename: Ana-Maria
authors.initials: AM
authors.lastname: Gheldiu
authors.affiliation: Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, 8, V. Babes Street, Cluj-Napoca 400010, Romania. mocan.andrei@umfcluj.ro.
authors.forename: Andrei
authors.initials: A
authors.lastname: Mocan
authors.affiliation: Faculty of Pharmacy, Iuliu Hatieganu University of Medicine and Pharmacy, 8, V. Babes Street, Cluj-Napoca 400010, Romania. laurian.vlase@umfcluj.ro.
authors.forename: Laurian
authors.initials: L
authors.lastname: Vlase
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D005052:Eucalyptus / Q000737:chemistry; D015227:Lipid Peroxidation / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D027822:Myrtaceae / Q000737:chemistry* / Q000145:classification; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D059808:Polyphenols / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D010936:Plant Extracts; D059808:Polyphenols