title: Magnetic, fluorescent, and thermo-responsive poly(MMA-NIPAM-Tb(AA)3Phen)/Fe3O4 multifunctional nanospheres prepared by emulsifier-free emulsion polymerization.
abstract: Magnetic, luminescent, and thermoresponsive multifunctional nanospheres composed of modified Fe3O4 nanoparticles as the core and rare earth complex Tb(AA)3Phen as the shell are synthesized by emulsifier-free emulsion polymerization. The core-shell spherical structure has a size between 140 and 220 nm and exhibits strong green fluorescence of the rare earth complex Tb(AA)3Phen. In the R2 relaxivity and in vivo MRI studies, the R2 relaxivity of the nanospheres is 562.56 mM(-1) s(-1) and enhanced T2-weighted images are observed from the nanospheres in the liver and spleen after injection as a contrast agent. The excellent superparamagnetic, thermosensitive, and fluorescent properties render the nanospheres useful in biomedical engineering and optical imaging.
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry of Education Key Laboratory for The Green Preparation and Application of Functional Material, Hubei University, Wuhan, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Gong
authors.affiliation: Department of Radiology at Union Hospital Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
authors.forename: Jingwen
authors.initials: J
authors.lastname: Dai
authors.affiliation: Department of Radiology at Union Hospital Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
authors.forename: Huan
authors.initials: H
authors.lastname: Li
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry of Education Key Laboratory for The Green Preparation and Application of Functional Material, Hubei University, Wuhan, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry of Education Key Laboratory for The Green Preparation and Application of Functional Material, Hubei University, Wuhan, China.
authors.forename: Haoran
authors.initials: H
authors.lastname: Xiong
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry of Education Key Laboratory for The Green Preparation and Application of Functional Material, Hubei University, Wuhan, China.
authors.forename: Quanyuan
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China.
authors.forename: Penghui
authors.initials: P
authors.lastname: Li
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry of Education Key Laboratory for The Green Preparation and Application of Functional Material, Hubei University, Wuhan, China.
authors.forename: Changfeng
authors.initials: C
authors.lastname: Yi
authors.affiliation: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry of Education Key Laboratory for The Green Preparation and Application of Functional Material, Hubei University, Wuhan, China Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China zushunxu@hubu.edu.cn.
authors.forename: Zushun
authors.initials: Z
authors.lastname: Xu
authors.affiliation: Department of Radiology at Union Hospital Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
authors.forename: Haibo
authors.initials: H
authors.lastname: Xu
authors.affiliation: Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China.
authors.forename: Paul K
authors.initials: PK
authors.lastname: Chu
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D000818:Animals; D004655:Emulsions; D052203:Ferrosoferric Oxide / Q000737:chemistry*; D057809:HEK293 Cells; D006801:Humans; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D051379:Mice; D008854:Microscopy, Electron; D054118:Nanospheres; D058105:Polymerization; D011109:Polymethacrylic Acids / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D000180:Acrylic Resins; D004655:Emulsions; D011109:Polymethacrylic Acids; D052203:Ferrosoferric Oxide
keywords: Luminescence; magnetic properties; nanostructure; rare earth