title: Pernicious anemia presenting as catatonia: correlating vitamin B12 levels and catatonic symptoms.
abstract: Pernicious anemia has been associated with various psychiatric manifestations, such as depression, mania and psychosis. Psychiatric symptoms can sometimes occur without hematological and neurological abnormalities and can be prodromal of vitamin B12 deficiency. We report a case of autoimmune B12 deficiency presenting as catatonia without signs of anemia or macrocytosis, in which a correlation was found between the patient's B12 blood levels and catatonic symptoms over time. This catatonic episode was successfully treated with only lorazepam and adequate doses of cyanocobalamin.
authors.affiliation: EPSM des Flandres, Bailleul, France; Department of Psychiatry, CHU Lille, Lille, France. Electronic address: damien.bram@gmail.com.
authors.forename: Damien
authors.initials: D
authors.lastname: Bram
authors.affiliation: Université Lille Nord de France, Lille, France; Department of Psychiatry, CHU Lille, Lille, France. Electronic address: maxime.bubrovszky@chru-lille.fr.
authors.forename: Maxime
authors.initials: M
authors.lastname: Bubrovszky
authors.affiliation: EPSM des Flandres, Bailleul, France. Electronic address: Jean-Paul.Durand@epsm-des-flandres.com.
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Durand
authors.affiliation: Université Lille Nord de France, Lille, France; Department of Internal Medicine, National Reference Center for Rare Autoimmune and Systemic Diseases, CHRU Lille, Lille, France. Electronic address: guillaume.lefevre@chru-lille.fr.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Lefevre
authors.affiliation: Université Lille Nord de France, Lille, France; Department of Internal Medicine, National Reference Center for Rare Autoimmune and Systemic Diseases, CHRU Lille, Lille, France. Electronic address: sandrine.dubois@chru-lille.fr.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Morell-Dubois
authors.affiliation: Université Lille Nord de France, Lille, France; Department of Psychiatry, CHU Lille, Lille, France. Electronic address: guillaume.vaiva@chru-lille.fr.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Vaiva
mesh_terms: D000752:Anemia, Pernicious / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D002389:Catatonia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D014805:Vitamin B 12 / Q000097:blood*
chemical_list: D014805:Vitamin B 12
keywords: Catatonia; Psychiatry; Vitamin B12 deficiency; Vitamins