title: Forensic evaluation and population genetic study of 30 insertion/deletion polymorphisms in a Chinese Yi group.
abstract: Insertion/deletion polymorphisms have become a research hot spot in forensic science due to their tremendous potential in recent years. In the present study, we investigated 30 indel loci in a Chinese Yi ethnic group. The allele frequencies of the short allele of the 30 indel loci were in the range of 0.1025-0.9221. The power of discrimination values were observed ranging from to 0.2630 (HLD111 locus) to 0.6607 (HLD70 locus) and probability of exclusion values ranged from 0.0189 (HLD111 locus) to 0.2343 (HLD56 locus). The combined power of discrimination and power of exclusion for 30 loci in the studied Yi group were 0.99999999995713 and 0.97746, respectively, which showed tremendous potential for forensic personal identification in the Yi group. Moreover, the DA distances, phylogenetic tree, principal component analysis, and cluster analysis showed the Yi group had close genetic relationships with the Tibetan, South Korean, Chinese Han, and She groups.
authors.affiliation: Research Center of Stomatology, Stomatological Hospital, Xi'an Jiaotong University, Xi'an, P. R. China.|Key Laboratory of Evidence Science (China University of Political Science and Law), Ministry of Education, Beijing, P. R. China.
authors.forename: Yu-Dang
authors.initials: YD
authors.lastname: Zhang
authors.affiliation: Blood Center of Shaanxi Province, Xi'an, P. R. China.|College of Life Sciences, Shaanxi Normal University, Xi'an, P. R. China.
authors.forename: Chun-Mei
authors.initials: CM
authors.lastname: Shen
authors.affiliation: Department of Radiology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, P. R. China.
authors.forename: Rui
authors.initials: R
authors.lastname: Jin
authors.affiliation: College of Energy and Environmental Engineering, Yan'an University, Yan'an, P. R. China.
authors.forename: Ya-Ni
authors.initials: YN
authors.lastname: Li
authors.affiliation: College of Biological Technology, Xi'an University, Xi'an, P. R. China.
authors.forename: Bo
authors.initials: B
authors.lastname: Wang
authors.affiliation: Xi'an Jiaotong University Health Science Center, Xi'an, P. R. China.
authors.forename: Li-Xia
authors.initials: LX
authors.lastname: Ma
authors.affiliation: Research Center of Stomatology, Stomatological Hospital, Xi'an Jiaotong University, Xi'an, P. R. China.|Key Laboratory of Evidence Science (China University of Political Science and Law), Ministry of Education, Beijing, P. R. China.
authors.forename: Hao-Tian
authors.initials: HT
authors.lastname: Meng
authors.affiliation: Key Laboratory of Genome Sciences, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, P. R. China.
authors.forename: Jiang-Wei
authors.initials: JW
authors.lastname: Yan
authors.affiliation: Medical Genetic Institute of Henan Province, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, P. R. China.
authors.forename: Hong-
authors.initials: H
authors.lastname: Dan Wang
authors.affiliation: Xi'an Jiaotong University Health Science Center, Xi'an, P. R. China.
authors.forename: Ze-Long
authors.initials: ZL
authors.lastname: Yang
authors.affiliation: Research Center of Stomatology, Stomatological Hospital, Xi'an Jiaotong University, Xi'an, P. R. China.
authors.forename: Bo-Feng
authors.initials: BF
authors.lastname: Zhu
mesh_terms: D044466:Asian People / Q000145:classification / Q000235:genetics*; D002681:China; D005006:Ethnicity / Q000145:classification / Q000235:genetics*; D053803:Forensic Genetics; D005828:Genetics, Population; D006801:Humans; D054643:INDEL Mutation / Q000235:genetics*; D015810:Linkage Disequilibrium; D010802:Phylogeny; D011110:Polymorphism, Genetic
keywords: Evaluation; Forensic application; Genetic relationships; Indel; Yi ethnic group