title: Severe maxillofacial renal osteodystrophy in two patients with chronic kidney disease.
abstract: Renal osteodystrophy (ROD) is the bone pathology that occurs as an uncommon complication related to the several alterations in mineral metabolism present in patients with chronic kidney disease (CKD). This paper describes two cases of severe ROD affecting the maxilla and mandible and causing facial disfigurement of a young and a middle-aged female patient with CKD. Both patients had a history of secondary hyperparathyroidism, previously treated by surgery. The pathogenesis of the disease, as well as its clinical, imaging, and histopathological features, and management of the patient are discussed.
authors.affiliation: Postgraduate Program in Oral Pathology, Dentistry Department, Federal University of Rio Grande do Norte, Avenida Salgado Filho, 1787-Lagoa Nova, Natal, RN, CEP 59.056-000, Brazil, marialu.diniz@gmail.com.
authors.forename: Maria Luiza Diniz de Sousa
authors.initials: ML
authors.lastname: Lopes
authors.forename: Assis Filipe Medeiros
authors.initials: AF
authors.lastname: Albuquerque
authors.forename: Adriano Rocha
authors.initials: AR
authors.lastname: Germano
authors.forename: Lélia Maria Guedes
authors.initials: LM
authors.lastname: Queiroz
authors.forename: Márcia Cristina da Costa
authors.initials: MC
authors.lastname: Miguel
authors.forename: Éricka Janine Dantas
authors.initials: ÉJ
authors.lastname: da Silveira
mesh_terms: D000328:Adult; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000175:diagnosis* / Q000601:surgery; D005146:Facial Asymmetry / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D006957:Hyperostosis Frontalis Interna / Q000175:diagnosis* / Q000601:surgery*; D007676:Kidney Failure, Chronic / Q000175:diagnosis* / Q000601:surgery; D008336:Mandibular Diseases / Q000175:diagnosis* / Q000601:surgery; D008439:Maxillary Diseases / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D055815:Young Adult