title: [Influence of toxin botulin on walk stereotype of children with juvenile cerebral palsy. The functional examination performed by BTS, comprehensive movement analysis system. A preliminary report].
abstract: BACKGROUND
  Juvenile Cerebral Palsy--is caused by damage of the motor control centers of the developing brain (cerebral refers to the cerebrum, which is the affected area of the brain, although the disorder probably involves connections between the cortex and other parts of the brain and palsy refers to disorder of movement). The clinical symptoms of juvenile cerebral palsy are very diversified and include gross and fine motor-coordination disorders, manual ability, locomotion, perception and response, speech, psychomotor retardation, emotional disorders. The primary therapeutic problem in children with cerebral palsy is learning to move in a lower position and learning to walk. The aim of this research is evaluation the action of the botulinum toxin on gait pattern of children with cerebral palsy. Application of a comprehensive BTS analysis of gait will get accurate, consistent EBM (Evidence Base Medicine) results.
  
  
  METHODS
  The children with pyramidal syndrome of juvenile cerebral palsy have been included in the examinations. The children have been divided into 2 random groups: group I--children treated with standard therapy a neurodevelopmental rehabilitation and classic kinesiotherapy, group II--hildren treated with standard therapy --eurodevelopmental rehabilitation, classic kinesiotherapy and a botulinum toxin. The children were examined three times: before the therapy, after 6 weeks of treatment and after 3 months of treatment. In the research BTS comprehensive motion analysis system have been used where influence of toxin botulin on walk stereotype of children was assessed.
  
  
  RESULTS
  The treatment connected with standard rehabilitation and using botulinum toxin brings quicker walk improvement. Comparing the above treatment methods of influence on the walk stereotype of children with juvenile cerebral palsy, we can confirm, that standard treatment brings regular improvement, still, it requires longer period of time, often even 3 months. Using botulinum toxin brings quicker walk improvement, after 6 weeks only, which is a clear, but short-term result.
  
  
  CONCLUSIONS
  Botulinum toxin has a positive effect on gait parameters in children, especially until 3 months, after this time parameters are not better..Concomitant treatment with standard therapy and botulinum toxin should be used becouse it is possitive treatment for locomotion of children with cerebral palsy.
authors.forename: Ilona
authors.initials: I
authors.lastname: Kwiecień-Czerwieniec
authors.forename: Jolanta
authors.initials: J
authors.lastname: Krukowska
authors.forename: Marta
authors.initials: M
authors.lastname: Woldańska-Okońska
mesh_terms: D000293:Adolescent; D001905:Botulinum Toxins / Q000627:therapeutic use*; D002547:Cerebral Palsy / Q000188:drug therapy* / Q000534:rehabilitation*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005684:Gait / Q000187:drug effects*; D006801:Humans; D007223:Infant; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects*; D016896:Treatment Outcome; D016138:Walking
chemical_list: D001905:Botulinum Toxins