title: DNA-templated in situ growth of silver nanoparticles on mesoporous silica nanospheres for smart intracellular GSH-controlled release.
abstract: In this work, we propose a method for constructing silver nanoparticles (AgNPs) on mesoporous silica nanospheres (MSNs) by a DNA-templated process. By in situ formation, the gatekeeper can be easily modulated to meet different degrees of glutathione (GSH) stimuli for location-specific drug release.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Collaborative Innovation Center for Chemistry and Molecular Medicine, Hunan University, Changsha, 410082, P. R. China. yangrh@hnu.edu.cn.
authors.forename: Changhui
authors.initials: C
authors.lastname: Liu
authors.forename: Zhihe
authors.initials: Z
authors.lastname: Qing
authors.forename: Jing
authors.initials: J
authors.lastname: Zheng
authors.forename: Li
authors.initials: L
authors.lastname: Deng
authors.forename: Cheng
authors.initials: C
authors.lastname: Ma
authors.forename: Jishan
authors.initials: J
authors.lastname: Li
authors.forename: Yinhui
authors.initials: Y
authors.lastname: Li
authors.forename: Sheng
authors.initials: S
authors.lastname: Yang
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Weihong
authors.initials: W
authors.lastname: Tan
authors.forename: Ronghua
authors.initials: R
authors.lastname: Yang
mesh_terms: D004247:DNA / Q000737:chemistry*; D003692:Delayed-Action Preparations; D004337:Drug Carriers / Q000737:chemistry*; D005978:Glutathione / Q000378:metabolism*; D006367:HeLa Cells; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*
chemical_list: D003692:Delayed-Action Preparations; D004337:Drug Carriers; D012834:Silver; D012822:Silicon Dioxide; D004247:DNA; D005978:Glutathione