title: Aqueous self-assembly of a charged BODIPY amphiphile via nucleation-growth mechanism.
abstract: A new amphiphilic boron-dipyrromethene (BODIPY) dye 1 with a hydrophobic wedge at the meso-position and two hydrophilic cationic moieties at boron was synthesized. Temperature- and concentration-dependent UV/Vis spectroscopic studies in water were conducted to explore the self-assembly process of the dye. Detailed analysis of the data using two different models (developed by Van der Schoot et al. and Goldstein et al. respectively) for cooperative supramolecular polymerization indicates distinctly a nucleation-growth mechanism of the aggregation of dye 1 and the nucleus size (ca. 12-18 molecules) and a cooperativity factor (ca. 0.01) could be derived. Further investigation by transmission electron microscopy, scanning confocal microscopy, and X-ray diffraction revealed a unique vesicular morphology of the aggregates with multilamellar wall structure. Meanwhile, these dye vesicles exhibit unique optical characteristics, i.e. red-shifted sharp absorption band, narrowed emission linewidth, and increase in fluorescence quantum yield, as compared with the monomeric dye.
authors.affiliation: School of Chemical Engineering and Technology, and Collaborative Innovation Center of Chemical Science and Chemical Engineering (Tianjin), Tianjin University, Tianjin, 300072, China. zjchen@tju.edu.cn.
authors.forename: Le
authors.initials: L
authors.lastname: Yang
authors.forename: Gang
authors.initials: G
authors.lastname: Fan
authors.forename: Xiangkui
authors.initials: X
authors.lastname: Ren
authors.forename: Lingyun
authors.initials: L
authors.lastname: Zhao
authors.forename: Jingkang
authors.initials: J
authors.lastname: Wang
authors.forename: Zhijian
authors.initials: Z
authors.lastname: Chen