title: Uncommon presentations of common pancreatic neoplasms: a pictorial essay.
abstract: Pancreatic neoplasms are a wide group of solid and cystic lesions with different and often characteristic imaging features, clinical presentations, and management. Among solid tumors, ductal adenocarcinoma is the most common: it arises from exocrine pancreas, comprises about 90% of all pancreatic neoplasms, and generally has a bad prognosis; its therapeutic management must be multidisciplinary, involving surgeons, oncologists, gastroenterologists, radiologists, and radiotherapists. The second most common solid pancreatic neoplasms are neuroendocrine tumors: they can be divided into functioning or non-functioning and present different degrees of malignancy. Cystic pancreatic neoplasms comprise serous neoplasms, which are almost always benign, mucinous cystic neoplasms and intraductal papillary mucinous neoplasms, which can vary from benign to frankly malignant lesions, and solid pseudopapillary tumors. Other pancreatic neoplasms, such as lymphoma, metastases, or pancreatoblastoma, are rarely seen in clinical practice and have different and sometimes controversial managements. Rare clinical presentations and imaging appearance of the most common pancreatic neoplasms, both solid and cystic, are more frequently seen and clinically relevant than rare pancreatic tumors; their pathologic and radiologic appearances must be known to improve their management. The purpose of this paper is to present some rare or uncommon clinical and radiological presentations of common pancreatic neoplasms providing examples of multi-modality imaging approach with pathologic correlations, thus describing the histopathological bases that can explain the peculiar imaging features, in order to avoid relevant misdiagnosis and to improve lesion management.
authors.affiliation: Department of Radiology, G.B. Rossi Hospital, University of Verona, Piazzale L.A. Scuro, 10, 37134, Verona, Italy, mirko.donofrio@univr.it.
authors.forename: Mirko
authors.initials: M
authors.lastname: D'Onofrio
authors.forename: Riccardo
authors.initials: R
authors.lastname: De Robertis
authors.forename: Paola
authors.initials: P
authors.lastname: Capelli
authors.forename: Paolo
authors.initials: P
authors.lastname: Tinazzi Martini
authors.forename: Stefano
authors.initials: S
authors.lastname: Crosara
authors.forename: Stefano
authors.initials: S
authors.lastname: Gobbo
authors.forename: Giovanni
authors.initials: G
authors.lastname: Butturini
authors.forename: Roberto
authors.initials: R
authors.lastname: Salvia
authors.forename: Emilio
authors.initials: E
authors.lastname: Barbi
authors.forename: Roberto
authors.initials: R
authors.lastname: Girelli
authors.forename: Claudio
authors.initials: C
authors.lastname: Bassi
authors.forename: Paolo
authors.initials: P
authors.lastname: Pederzoli
mesh_terms: D003287:Contrast Media; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging; D010179:Pancreas / Q000000981:diagnostic imaging / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D003287:Contrast Media