title: [Pathophysiology of hypertension in chronic kidney disease].
abstract: Hypertension is both an important cause and consequence of chronic kidney disease (CKD). It is present in 80-85% of the patients. The article summarizes the main pathogenetic factors of hypertension in CKD such as: sodium retention, increased activity the renin-angiotensin-aldosterone system and sympathetic nervous system, impaired nitric oxide synthesis and endothelium-mediated vasodilatation, oxidative stress, disorders of calcium metabolism and parathyroid hormone secretion, vascular calcification and increased arterial stiffness.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Sawicka
authors.forename: Mirosław
authors.initials: M
authors.lastname: Jędras
mesh_terms: D015984:Causality; D015897:Comorbidity; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000503:physiopathology*; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D012084:Renin-Angiotensin System