title: 4th international conference on tumor progression and therapeutic resistance: meeting report.
abstract: The fourth international conference on tumor progression and therapeutic resistance organized in association with GTCbio was held in Boston, MA from March 9 to 11, 2014. The meeting attracted a diverse group of experts in the field of cancer biology, therapeutics and medical oncology from academia and industry. The meeting addressed the current challenges in the treatment of cancer including tumor heterogeneity, therapy resistance and metastasis along with the need for improved biomarkers of tumor progression and clinical trial design. Keynote speakers included Clifton Leaf, Editor at Fortune Magazine, Dr. Mina Bissell from the Lawrence Berkeley National Laboratory and Dr. Levi Garraway from the Dana Farber Cancer Institute. The meeting featured cutting edge tools, preclinical models and the latest basic, translational and clinical research findings in the field.
authors.affiliation: a Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Department of Hematology/Oncology and Molecular Therapeutics Program , Fox Chase Cancer Center , Philadelphia , PA , USA.
authors.forename: Varun V
authors.initials: VV
authors.lastname: Prabhu
authors.forename: Wafik S
authors.initials: WS
authors.lastname: El-Deiry
mesh_terms: D063646:Carcinogenesis; D019008:Drug Resistance, Neoplasm; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology
keywords: cancer stem cell; cancer therapy; driver mutation; metastasis; therapeutic resistance; translational medicine; tumor heterogeneity; tumor microenvironment; tumor progression