title: Usefulness of (131)I-SPECT/CT and (18)F-FDG PET/CT in Evaluating Successful (131)I and Retinoic Acid Combined Therapy in a Patient with Metastatic Struma Ovarii.
abstract: Metastatic struma ovarii is an extremely rare disease, and the treatment of choice has not been established. Here, we introduce the case of a 36-year-old female pregnant patient with metastatic struma ovarii. Initial treatment was an exploratory laparotomy to remove multiple peritoneal masses. After delivery, a total thyroidectomy was done for the further (131)I-therapy. (131)I-SPECT/CT and (18) F-FDG PET/CT showed multiple hepatic metastases and extensive peritoneal seeding nodules. Multiple (131)I and retinoic acid combination therapies were performed, resulting in marked improvement. (131)I-SPECT/CT and (18) F-FDG PET/CT were quite useful for evaluating the biologic characteristics of the metastases.
authors.affiliation: Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul, Korea ; Department of Nuclear Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehangno, Jongro-gu, Seoul, 110-744 Korea ; Department of Nuclear Medicine, Anyang SAM Hospital, Gyeonggi-do, Korea.
authors.forename: Hyo Jung
authors.initials: HJ
authors.lastname: Seo
authors.affiliation: Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Young Hoon
authors.initials: YH
authors.lastname: Ryu
authors.affiliation: Department of Nuclear Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehangno, Jongro-gu, Seoul, 110-744 Korea.
authors.forename: Inki
authors.initials: I
authors.lastname: Lee
authors.affiliation: Department of Pathology, Seoul National University Hospital, Seoul, Korea.
authors.forename: Hye Sook
authors.initials: HS
authors.lastname: Min
authors.affiliation: Department of Nuclear Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehangno, Jongro-gu, Seoul, 110-744 Korea.
authors.forename: Keon Wook
authors.initials: KW
authors.lastname: Kang
authors.affiliation: Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul, Korea ; Department of Nuclear Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehangno, Jongro-gu, Seoul, 110-744 Korea.
authors.forename: Dong Soo
authors.initials: DS
authors.lastname: Lee
authors.affiliation: Departiment of Oncology, GSAM Hosptial, Gyeonggi-do, Korea.
authors.forename: Dae-Hee
authors.initials: DH
authors.lastname: Lee
authors.affiliation: Department of Nuclear Medicine, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehangno, Jongro-gu, Seoul, 110-744 Korea.
authors.forename: June-Key
authors.initials: JK
authors.lastname: Chung