title: [On the issue of non-mutagenic non-targeted effects in low renewable tissues. Analysis of low dose radiation effects on the rat renal tubule epithelium].
abstract: Irradiation of rats with γ-quanta at relatively low doses induces a sustainable dose-independent increase in the occurrence of lethal cytoplasmic disorders in the renal tubules epithelium together with sustainable and as well dose-independent subcelluar compensation and restorative processes. Over the period of research (6 months) these processes led to no population recovery. The detected alterations are referred to the category of non-targeted non-mutagenic effects and they are of interest because they address the issue of the sensitivity of low renewable tissues to radiation.
authors.forename: I B
authors.initials: IB
authors.lastname: Bychkovskaia
authors.forename: O V
authors.initials: OV
authors.lastname: Kirik
authors.forename: R F
authors.initials: RF
authors.lastname: Fedortseva
mesh_terms: D000222:Adaptation, Physiological / Q000528:radiation effects; D000818:Animals; D022083:Cytoplasmic Structures / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays / Q000009:adverse effects*; D007687:Kidney Tubules, Proximal / Q000502:physiology / Q000528:radiation effects* / Q000648:ultrastructure; D011829:Radiation Dosage; D051381:Rats; D012038:Regeneration / Q000528:radiation effects*; D013997:Time Factors; D019459:Urothelium / Q000502:physiology / Q000528:radiation effects* / Q000648:ultrastructure