title: [Histological classification and quality of life in women with endometriosis].
abstract: OBJECTIVE
  To assess the relationship between the histological classification and the quality of life of patients operated for endometriosis.
  
  
  METHODS
  A cross-sectional observational study, with assessment of 32 biopsies of the intestine, peritoneum and uterosacral ligament from 40 women with deep endometriosis. The quality of life (QOL) was determined by applying the SF-36 questionnaire pre-operatively and at 6 and 12 months postoperatively. Biopsies were histologically classified into pure stromal (EP), glandular differentiated (GD), glandular undifferentiated (GI) and mixed (GM), remaining in the sample only GI and GM, which are related to eight domains of the SF-36.
  
  
  RESULTS
  According to the histologic type, the following distribution was observed: peritoneum 63% GI and 35% GM; intestine 19% GI and 24% GM; uterosacral ligament with 41% GI and 35% GM. Regarding the QOL and the histological classification, in the intestine only GM was associated with improvement of social and emotional aspects from 0 to 6 months; the domains general health status (p=0.01) and social aspect (p=0.04) were significantly related to improvement of the QOL from 0 to 6 months, and the general health status tended to improve from 0 to 12 months. Regarding pain (p=0.06) and the emotional aspect (p=0.05), the QOL tended to improve from 0 to 6 months and the vital capacity (p=0.1) improved from 0 to 6 months and from 0 to 12 months. Regarding the emotional aspect, evolution of the two histological types was not favorable for improvement in MG from 0 to 6 months. No significant relationships between histologic type and QOL were evident in the uterosacral ligament samples.
  
  
  CONCLUSIONS
  Improvement in the QOL of women undergoing laparoscopic surgery for deep endometriosis is associated with the histologic grade. The peritoneal biopsy of GI revealed improved QOL after surgery.
authors.affiliation: Departamento de Obstetrícia e Ginecologia, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brasil.
authors.forename: Beatriz Taliberti da Costa
authors.initials: BT
authors.lastname: Porto
authors.affiliation: Departamento de Obstetrícia e Ginecologia, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brasil.
authors.forename: Helizabet Salomão Abdalla Ayrosa
authors.initials: HS
authors.lastname: Ribeiro
authors.affiliation: Departamento de Patologia, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brasil.
authors.forename: Maria Antonieta Longo
authors.initials: MA
authors.lastname: Galvão
authors.affiliation: Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brasil.
authors.forename: Vanessa Gozzo
authors.initials: VG
authors.lastname: Sekula
authors.affiliation: Departamento de Obstetrícia e Ginecologia, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brasil.
authors.forename: José Mendes
authors.initials: JM
authors.lastname: Aldrigui
authors.affiliation: Departamento de Obstetrícia e Ginecologia, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brasil.
authors.forename: Paulo Augusto Ayrosa
authors.initials: PA
authors.lastname: Ribeiro
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D004715:Endometriosis / Q000145:classification / Q000473:pathology*; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000145:classification / Q000473:pathology*; D010532:Peritoneal Diseases / Q000145:classification / Q000473:pathology*; D010865:Pilot Projects; D011788:Quality of Life