title: A topical haemoglobin spray for oxygenating pressure ulcers: a pilot study.
abstract: The effect of pressure ulcers on patient quality of life have been recognised as a real problem for many years, and the need for robust and effective management of pressure ulcers is now a prominent national health-care issue. Myriad different interventions exist for the treatment of pressure ulcers, including clinically effective dressings and pressure-relieving devices, yet many pressure ulcers still do not heal and often become a chronic wound. This is the second of a series of articles (Norris, 2014) discussing the clinical evaluation of a topical oxygen therapy in practice. It describes a small evaluation involving 18 patients with pressure ulcers. The study set out to determine the effect of a topical oxygen therapy on wound size. The therapy comprises a canister that sprays pure haemoglobin in a water solution into or onto the wound. The haemoglobin spray needs to be used at least once every 3 days, does not require training on its use and can be used in any care setting. Overall, results identified wound healing progression in all 18 wounds and wound size reduction in 17 of the 18 wounds.
authors.affiliation: Tissue Viability Specialist, Shropshire Community NHS Trust.
authors.forename: Joy
authors.initials: J
authors.lastname: Tickle
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D004739:England; D005260:Female; D006454:Hemoglobins / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009779:Occlusive Dressings; D010100:Oxygen / Q000008:administration & dosage*; D010865:Pilot Projects; D003668:Pressure Ulcer / Q000628:therapy*; D014647:Varicose Ulcer / Q000628:therapy*; D014945:Wound Healing / Q000502:physiology*
chemical_list: D000891:Anti-Infective Agents, Local; D006454:Hemoglobins; D010100:Oxygen
keywords: Chronic wound; Pressure ulceration; Topical oxygen therapy; Wound size reduction