title: Selective detection of tyrosine-containing proximally phosphorylated motifs using an antenna-free Tb³⁺ luminescent sensor.
abstract: We herein report the first application of Tb(3+) for the selective detection of an important subset of the phosphoproteome, namely, proximally di-phosphorylated peptide motifs where at least one phosphorylated residue is tyrosine.
authors.affiliation: University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, Ontario, L5L 1C6 Canada. patrick.gunning@utoronto.ca.
authors.forename: Eugenia
authors.initials: E
authors.lastname: Duodu
authors.forename: Dziyana
authors.initials: D
authors.lastname: Kraskouskaya
authors.forename: Joshua
authors.initials: J
authors.lastname: Campbell
authors.forename: Gustavo
authors.initials: G
authors.lastname: Graca-Lima
authors.forename: Patrick T
authors.initials: PT
authors.lastname: Gunning
mesh_terms: D020816:Amino Acid Motifs; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D008163:Luminescent Measurements; D008958:Models, Molecular; D010750:Phosphoproteins / Q000032:analysis* / Q000737:chemistry*; D010766:Phosphorylation; D013725:Terbium / Q000737:chemistry*; D014443:Tyrosine
chemical_list: D010750:Phosphoproteins; D013725:Terbium; D014443:Tyrosine