title: Transapical implantation of a new second-generation transcatheter heart valve in patients with pure aortic regurgitation: a preliminary report.
abstract: Transcatheter aortic valve implantation (TAVI) has become an effective treatment option for high-risk or inoperable patients with aortic stenosis. However, experience with TAVI for non-calcified aortic regurgitation is still limited. The new J-Valve(™) system is a new second-generation TAVI device that is designed for transapical implantation. It is characterized by three U-shaped, anatomically oriented devices-'graspers' that could facilitate intuitive 'self-positioning' valve implantation and provide extra-radial fixation by embracing the native valve leaflets. Here, we reported the initial experience of TAVI in high-risk patients with pure aortic regurgitation using the J-Valve(™) system.
authors.affiliation: Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
authors.forename: Da
authors.initials: D
authors.lastname: Zhu
authors.affiliation: Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
authors.forename: Yucheng
authors.initials: Y
authors.lastname: Chen
authors.affiliation: JC Medical, Inc., Redwood City, CA, USA.
authors.forename: Ji
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Hu
authors.affiliation: Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China drguoyq@hotmail.com.
authors.forename: Yingqiang
authors.initials: Y
authors.lastname: Guo
mesh_terms: D000368:Aged; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D008297:Male; D011474:Prosthesis Design; D015641:Radiography, Interventional; D012307:Risk Factors; D016896:Treatment Outcome
keywords: J-Valve™ system; Pure aortic regurgitation; Second-generation transcatheter aortic valve implantation device; Transcatheter aortic valve implantation