title: One-time umbilical cord milking after cord cutting has same effectiveness as multiple-time umbilical cord milking in infants born at <29 weeks of gestation: a retrospective study.
abstract: OBJECTIVE
  To compare two strategies to potentiate the effects of placental transfusion in infants born at <29 weeks of gestation.
  
  
  METHODS
  Twenty infants who received one-time umbilical cord milking after umbilical cord cutting were compared with 20 infants from a previous study group who received multiple-time umbilical cord milking. The primary outcome measurements were the probability of not needing a red blood cell (RBC) transfusion during the hospital stay and the total number of RBC transfusions within 21 days after birth.
  
  
  RESULTS
  There was no significant difference in the probability of not needing a transfusion during the hospital stay (P=0.75) and the mean number of RBC transfusions given within the first 21 days of life (1.1±1.8 for the one-time umbilical cord-milking group vs 0.7±1.2 for the multiple-time umbilical cord-milking group, P=0.48).
  
  
  CONCLUSIONS
  One-time umbilical cord milking after umbilical cord cutting had similar beneficial effects to multiple-time umbilical cord milking before umbilical cord cutting in very premature infants.
authors.affiliation: Division of Neonatology, Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Hosono
authors.affiliation: Division of Neonatology, Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Mugishima
authors.affiliation: Division of Neonatology, Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Takahashi
authors.affiliation: Division of Neonatology, Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Takahashi
authors.affiliation: 1] Department of Obstetrics and Gynecology, Tokyo Women's Medical University Yachiyo Medical Center, Chiba, Japan [2] Department of Obstetrics and Gynecology, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Masaoka
authors.affiliation: Department of Obstetrics and Gynecology, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.affiliation: Division of Neonatal Medicine, Center for Maternal, Fetal and Neonatal Medicine, Saitama Medical University Kawagoe Medical Center, Saitama, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tamura
mesh_terms: D003250:Constriction; D005260:Female; D005865:Gestational Age; D006400:Hematocrit; D006801:Humans; D007223:Infant; D062071:Infant, Extremely Premature / Q000097:blood*; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight / Q000097:blood*; D007363:Intensive Care Units, Neonatal; D007564:Japan; D053208:Kaplan-Meier Estimate; D008297:Male; D021041:Placental Circulation / Q000502:physiology*; D011247:Pregnancy; D012189:Retrospective Studies; D014470:Umbilical Cord / Q000098:blood supply*