title: Study of non-compliance among chronic hemodialysis patients and its impact on patients' outcomes.
abstract: Non-adherence to prescription is common among hemodialysis (HD) patients and has been associated with significant morbidity. At least 50% of HD patients are believed to be non-adherent to some part of their treatment. We aimed to assess the prevalence of non-adherence to dialysis prescription among 100 chronic HD patients. We explored the relationship between non-adherence on one hand and socioeconomic profile, depression scores and cognitive function on the other hand. The impact of patients' non-adherence on nutritional status, quality of life and dialysis adequacy was also assessed. The mean age of the study group was 50.51 ± 12.0 years. There were 62 females and 38 males in the study. Thirty-six patients (36%) were non-compliant to their dialysis prescription. No significant differences were detected between compliant and non-compliant patients in their education level and employment status. Inter-dialytic weight gain, serum phosphorus and depression scores were significantly higher in non-compliant patients compared with compliant patients, whereas body weight, serum albumin, serum calcium, quality of life scores and nutrition scores were significantly higher in compliant patients (P <0.05). In conclusion, non-adherence is highly prevalent among chronic HD patients and is associated with poor quality of life, depression and malnutrition.
authors.affiliation: Department of Internal Medicine, Cairo University, Cairo, Egypt.
authors.forename: Salwa
authors.initials: S
authors.lastname: Ibrahim
authors.forename: Mohammed
authors.initials: M
authors.lastname: Hossam
authors.forename: Dawlat
authors.initials: D
authors.lastname: Belal
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D003071:Cognition; D003072:Cognition Disorders / Q000453:epidemiology / Q000523:psychology; D003863:Depression / Q000453:epidemiology / Q000523:psychology; D004534:Egypt / Q000453:epidemiology; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000453:epidemiology / Q000523:psychology; D008875:Middle Aged; D009752:Nutritional Status; D010349:Patient Compliance; D010361:Patients / Q000523:psychology*; D055656:Prescriptions; D015995:Prevalence; D011788:Quality of Life; D006435:Renal Dialysis / Q000523:psychology*; D051436:Renal Insufficiency, Chronic / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology / Q000628:therapy*; D012307:Risk Factors; D012959:Socioeconomic Factors
chemical_list: D015415:Biomarkers