title: PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma.
authors.affiliation: Clinica Universidad de Navarra, Pamplona, Spain.|Centro de Investigaciones Medicas Aplicadas (CIMA), Pamplona, Spain.|Instituto de Investigación Sanitaria de Navarra (IDISNA), Pamplona, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Paiva
authors.affiliation: Centro de Investigaciones Medicas Aplicadas (CIMA), Pamplona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Azpilikueta
authors.affiliation: Hospital Universitario de Salamanca, IBSAL, IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Puig
authors.affiliation: Hospital Universitario de Salamanca, IBSAL, IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: E M
authors.initials: EM
authors.lastname: Ocio
authors.affiliation: University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
authors.forename: R
authors.initials: R
authors.lastname: Sharma
authors.affiliation: University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
authors.forename: B O
authors.initials: BO
authors.lastname: Oyajobi
authors.affiliation: Centro de Investigaciones Medicas Aplicadas (CIMA), Pamplona, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Labiano
authors.affiliation: Hospital Universitario de Salamanca, IBSAL, IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: L
authors.initials: L
authors.lastname: San-Segundo
authors.affiliation: Instituto de Investigación Sanitaria de Navarra (IDISNA), Pamplona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Rodriguez
authors.affiliation: Hospital Universitario de Salamanca, IBSAL, IBMCC (USAL-CSIC), Salamanca, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Aires-Mejia
authors.affiliation: Centro de Investigaciones Medicas Aplicadas (CIMA), Pamplona, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Rodriguez
authors.affiliation: Complejo Hospitalario de Leon, Leon, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Escalante
authors.affiliation: Hospital Clinico Universitario de Valladolid, Valladolid, Spain.
authors.forename: A G
authors.initials: AG
authors.lastname: de Coca
authors.affiliation: Hospital Nuestra Señora de Sonsoles, Avila, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Barez
authors.affiliation: Clinica Universidad de Navarra, Pamplona, Spain.|Centro de Investigaciones Medicas Aplicadas (CIMA), Pamplona, Spain.|Instituto de Investigación Sanitaria de Navarra (IDISNA), Pamplona, Spain.
authors.forename: J F
authors.initials: JF
authors.lastname: San Miguel
authors.affiliation: Clinica Universidad de Navarra, Pamplona, Spain.|Centro de Investigaciones Medicas Aplicadas (CIMA), Pamplona, Spain.|Instituto de Investigación Sanitaria de Navarra (IDISNA), Pamplona, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Melero
mesh_terms: D000818:Animals; D060890:B7-H1 Antigen / Q000378:metabolism*; D001853:Bone Marrow / Q000378:metabolism*; D016022:Case-Control Studies; D002478:Cells, Cultured; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016130:Immunophenotyping; D007694:Killer Cells, Natural / Q000378:metabolism / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D009101:Multiple Myeloma / Q000378:metabolism / Q000401:mortality / Q000473:pathology*; D009364:Neoplasm Recurrence, Local / Q000378:metabolism / Q000401:mortality / Q000473:pathology*; D009367:Neoplasm Staging; D018365:Neoplasm, Residual / Q000378:metabolism / Q000401:mortality / Q000473:pathology*; D011379:Prognosis; D061026:Programmed Cell Death 1 Receptor / Q000037:antagonists & inhibitors* / Q000378:metabolism; D011446:Prospective Studies; D013234:Stem Cells / Q000378:metabolism / Q000473:pathology; D015996:Survival Rate; D013601:T-Lymphocytes / Q000378:metabolism / Q000473:pathology; D059016:Tumor Microenvironment
chemical_list: D060890:B7-H1 Antigen; C105992:PDCD1 protein, human; D061026:Programmed Cell Death 1 Receptor