title: Missed opportunities for tetanus postexposure prophylaxis--California, January 2008-March 2014.
abstract: Tetanus is an acute and sometimes fatal disease characterized by sudden muscle contractions. The number of tetanus cases reported annually in the United States has declined significantly since the 1930s and 1940s as a result of the introduction of tetanus vaccines. However, sporadic cases continue to occur in persons who are not up-to-date with tetanus toxoid-containing vaccinations (TT) and do not receive appropriate postexposure prophylaxis (PEP). To assess the extent of these cases, the California Department of Public Health reviewed all tetanus cases reported during January 2008-March 2014. A total of 21 tetanus patients were reported; five (24%) died. An average of three cases were reported each year during 2008-2013; the average annual incidence among patients aged ≥65 years (0.23 cases per 1 million population) was twice that among patients aged 21-64 years (0.10 cases per 1 million population). Of 16 patients with an acute injury before illness and diagnosis, nine (56%) sought medical care, and two (22%) of the nine received appropriate PEP. Although tetanus is rare, it is a life-threatening disease that is preventable. Health care providers should ensure that their patients are up-to-date with TT vaccination and provide appropriate postexposure prophylaxis for patients with wounds.
authors.forename: Cynthia
authors.initials: C
authors.lastname: Yen
authors.forename: Erin
authors.initials: E
authors.lastname: Murray
authors.forename: Jennifer
authors.initials: J
authors.lastname: Zipprich
authors.forename: Kathleen
authors.initials: K
authors.lastname: Winter
authors.forename: Kathleen
authors.initials: K
authors.lastname: Harriman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002140:California / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D056990:Post-Exposure Prophylaxis / Q000706:statistics & numerical data*; D017410:Practice Guidelines as Topic; D013742:Tetanus / Q000453:epidemiology / Q000517:prevention & control*; D013745:Tetanus Toxoid / Q000008:administration & dosage; D014611:Vaccination / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D013745:Tetanus Toxoid