title: Infant pulmonary function testing in chronic pneumonitis of infancy due to surfactant protein C mutation.
abstract: Pulmonary function testing is a vital tool in evaluation and management of adult ILD patients and is rarely overlooked during workup. However, there is paucity of data regarding its usefulness in management of infants with suspected interstitial lung disease. In this paper, we present the contribution of infant pulmonary function testing (iPFT) to the management of two infants with biopsy confirmed chronic pneumonitis of infancy due to surfactant protein C mutation. We have productively and safely used serial iPFT for decision making both during diagnosis and follow-up of these infants.
authors.affiliation: Institute of Pulmonology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
authors.forename: Avigdor
authors.initials: A
authors.lastname: Hevroni
authors.affiliation: Institute of Pulmonology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
authors.forename: Aliza
authors.initials: A
authors.lastname: Goldman
authors.affiliation: Institute of Pulmonology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
authors.forename: Chaim
authors.initials: C
authors.lastname: Springer
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology; D009154:Mutation; D011014:Pneumonia / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology; D037721:Pulmonary Surfactant-Associated Protein C / Q000235:genetics*; D012129:Respiratory Function Tests
chemical_list: D037721:Pulmonary Surfactant-Associated Protein C
keywords: child interstitial lung disease (chILD); chronic pneumonitis of infancy (CPI); diffuse lung disease (DLD); infant pulmonary function testing (iPFT); surfactant protein C deficiency (SFTPC)