title: Sudden onset abdominal wall swellings in patient of liver cirrhosis.
abstract: Spontaneous hematomas in cirrhotic patients are uncommon. Severe coagulopathy in advanced hepatic disease is characterized by both coagulation factor deficiencies and accelerated fibrinolysis. Hyperfibrinolysis in cirrhosis is a result of excess fibrin breakdown leading to defective hemostasis. We present a case of spontaneous hematomas with an acute drop in hemoglobin level, in a patient with cirrhosis which was due to primary hyperfibrinolysis.
authors.affiliation: St. John's Medical College, Sarjapur Road, Koramangala, Bangalore, Karnataka 560034, India.
authors.forename: Mallikarjun
authors.initials: M
authors.lastname: Patil
authors.affiliation: St. John's Medical College, Sarjapur Road, Koramangala, Bangalore, Karnataka 560034, India.
authors.forename: Keyur A
authors.initials: KA
authors.lastname: Sheth
authors.affiliation: St. John's Medical College, Sarjapur Road, Koramangala, Bangalore, Karnataka 560034, India.
authors.forename: Kullembella S
authors.initials: KS
authors.lastname: Prasanna
authors.affiliation: St. John's Medical College, Sarjapur Road, Koramangala, Bangalore, Karnataka 560034, India.
authors.forename: Channagiri K
authors.initials: CK
authors.lastname: Adarsh
authors.affiliation: St. John's Medical College, Sarjapur Road, Koramangala, Bangalore, Karnataka 560034, India.
authors.forename: Balaraju
authors.initials: B
authors.lastname: Girisha
keywords: DIC, Disseminated intravascular coagulation; EACA, Epsilon amino-caproic acid; FDPs, Fibrin degradation products; PAI-1, Plasminogen activator inhibitor 1; TAFI, Thrombin-activatable fibrinolysis inhibitor; aPTT, Activated partial thromboplastin time; cirrhosis; muscle hematomas; primary hyperfibrinolysis; tPA, Tissue plasminogen activator