title: Primary hepatic diffuse large B-cell lymphoma: unusual presentation and imaging features.
abstract: Primary hepatic lymphoma is an uncommon malignancy affecting the liver, with limited reports and series in the literature. Imaging appearance is not well described, with no definite features suggesting a diagnosis, and it may mimic other focal hepatic lesions. However, biopsy is needed in most of the cases for confirmation. We report a case of 22-year-old pregnant woman who on ultrasonography showed a large heteroechoic solitary liver mass mimicking focal nodular hyperplasia. Further evaluation after parturition with contrast-enhanced magnetic resonance imaging showed a large mass with central scar and peripheral diffusion restriction and contrast enhancement, which was atypical. Biopsy confirmed it as lymphoma. The case illustrates unusual presentation and magnetic resonance imaging features, including diffusion-weighted imaging, of primary hepatic lymphoma in a young female.
authors.affiliation: Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Ekta
authors.initials: E
authors.lastname: Dhamija
authors.affiliation: Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India. Electronic address: drmadhuks@gmail.com.
authors.forename: Kumble S
authors.initials: KS
authors.lastname: Madhusudhan
authors.affiliation: Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.
authors.lastname: Shalimar
authors.affiliation: Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Prasenjit
authors.initials: P
authors.lastname: Das
authors.affiliation: Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Deep N
authors.initials: DN
authors.lastname: Srivastava
authors.affiliation: Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Arun K
authors.initials: AK
authors.lastname: Gupta
mesh_terms: D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis*; D055815:Young Adult