title: An atypical course of coxsackievirus A6 associated hand, foot and mouth disease in extremely low birth weight preterm twins.
abstract: The incidence of coxsackievirus A6 (CV-A6) associated hand, foot and mouth disease (HFMD) has reportedly increased since 2008 with sometimes severe complications. We here describe an atypical course of CV-A6-associated HFMD in extremely low birth weight twins. The CV-A6-strains are genetically closely related to international strains isolated from HFMD outbreaks.
authors.affiliation: Department of Pediatric Infectious Diseases, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: a.h.bruning@amc.uva.nl.
authors.forename: Andrea H L
authors.initials: AH
authors.lastname: Bruning
authors.affiliation: Department of Medical Microbiology, Laboratory of Clinical Virology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: s.m.g.vandersanden@amc.uva.nl.
authors.forename: Sabine M G
authors.initials: SM
authors.lastname: van der Sanden
authors.affiliation: Department of Neonatology, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Amber E
authors.initials: AE
authors.lastname: ten Hoedt
authors.affiliation: Department of Medical Microbiology, Laboratory of Clinical Virology, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Katja C
authors.initials: KC
authors.lastname: Wolthers
authors.affiliation: Department of Neonatology, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Anton H
authors.initials: AH
authors.lastname: van Kaam
authors.affiliation: Department of Pediatric Infectious Diseases, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Dasja
authors.initials: D
authors.lastname: Pajkrt
mesh_terms: D004200:Diseases in Twins / Q000175:diagnosis* / Q000821:virology; D004770:Enterovirus / Q000145:classification / Q000302:isolation & purification*; D005260:Female; D006232:Hand, Foot and Mouth Disease / Q000175:diagnosis* / Q000821:virology; D006801:Humans; D052577:Infant, Extremely Low Birth Weight; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis* / Q000821:virology; D008297:Male; D010802:Phylogeny; D012307:Risk Factors; D014427:Twins
keywords: Coxsackievirus A6; Hand, foot and mouth disease; Preterm