title: Computation and projection of spiral wave trajectories during atrial fibrillation: a computational study.
abstract: To show how atrial fibrillation rotor activity on the heart surface manifests as phase on the torso, fibrillation was induced on a geometrically accurate computer model of the human atria. The Hilbert transform, time embedding, and filament detection were compared. Electrical activity on the epicardium was used to compute potentials on different surfaces from the atria to the torso. The Hilbert transform produces erroneous phase when pacing for longer than the action potential duration. The number of phase singularities, frequency content, and the dominant frequency decreased with distance from the heart, except for the convex hull.
authors.affiliation: LIRYC Electrophysiology and Heart Modelling Institute, University of Bordeaux, PTIB-Campus Xavier, Arnozan, Avenue du Haut Lévèque, Bordeaux 33600, France; Inserm U1045, Cardiothoracic Research Center, 146 rue Léo-Saignat, Bordeaux Cedex 33076, France. Electronic address: ali.pashaei@ihu-liryc.fr.
authors.forename: Ali
authors.initials: A
authors.lastname: Pashaei
authors.affiliation: LIRYC Electrophysiology and Heart Modelling Institute, University of Bordeaux, PTIB-Campus Xavier, Arnozan, Avenue du Haut Lévèque, Bordeaux 33600, France; Inserm U1045, Cardiothoracic Research Center, 146 rue Léo-Saignat, Bordeaux Cedex 33076, France.
authors.forename: Jason
authors.initials: J
authors.lastname: Bayer
authors.affiliation: LIRYC Electrophysiology and Heart Modelling Institute, University of Bordeaux, PTIB-Campus Xavier, Arnozan, Avenue du Haut Lévèque, Bordeaux 33600, France; Inserm U1045, Cardiothoracic Research Center, 146 rue Léo-Saignat, Bordeaux Cedex 33076, France.
authors.forename: Valentin
authors.initials: V
authors.lastname: Meillet
authors.affiliation: LIRYC Electrophysiology and Heart Modelling Institute, University of Bordeaux, PTIB-Campus Xavier, Arnozan, Avenue du Haut Lévèque, Bordeaux 33600, France; Inserm U1045, Cardiothoracic Research Center, 146 rue Léo-Saignat, Bordeaux Cedex 33076, France.
authors.forename: Rémi
authors.initials: R
authors.lastname: Dubois
authors.affiliation: LIRYC Electrophysiology and Heart Modelling Institute, University of Bordeaux, PTIB-Campus Xavier, Arnozan, Avenue du Haut Lévèque, Bordeaux 33600, France; Bordeaux Institute of Mathematics UMR 5251, University of Bordeaux, 351 cours de la Libération, Talence 33405, France.
authors.forename: Edward
authors.initials: E
authors.lastname: Vigmond
mesh_terms: D000465:Algorithms; D001281:Atrial Fibrillation / Q000503:physiopathology*; D018780:Body Surface Potential Mapping; D003198:Computer Simulation; D004562:Electrocardiography / Q000379:methods*; D022062:Electrophysiologic Techniques, Cardiac / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008955:Models, Cardiovascular
keywords: Atrial fibrillation; Body surface potential map; Cardiac electrophysiology; Phase mapping