title: Mitochondrial genome sequences reveal evolutionary relationships of the Phytophthora 1c clade species.
abstract: Phytophthora infestans is one of the most destructive plant pathogens of potato and tomato globally. The pathogen is closely related to four other Phytophthora species in the 1c clade including P. phaseoli, P. ipomoeae, P. mirabilis and P. andina that are important pathogens of other wild and domesticated hosts. P. andina is an interspecific hybrid between P. infestans and an unknown Phytophthora species. We have sequenced mitochondrial genomes of the sister species of P. infestans and examined the evolutionary relationships within the clade. Phylogenetic analysis indicates that the P. phaseoli mitochondrial lineage is basal within the clade. P. mirabilis and P. ipomoeae are sister lineages and share a common ancestor with the Ic mitochondrial lineage of P. andina. These lineages in turn are sister to the P. infestans and P. andina Ia mitochondrial lineages. The P. andina Ic lineage diverged much earlier than the P. andina Ia mitochondrial lineage and P. infestans. The presence of two mitochondrial lineages in P. andina supports the hybrid nature of this species. The ancestral state of the P. andina Ic lineage in the tree and its occurrence only in the Andean regions of Ecuador, Colombia and Peru suggests that the origin of this species hybrid in nature may occur there.
authors.affiliation: Department of Biological Sciences, North Carolina State University, Raleigh, NC, 27695, USA.
authors.forename: Erica S
authors.initials: ES
authors.lastname: Lassiter
authors.affiliation: BROAD Institute, MIT, Cambridge, MA, 02142, USA.
authors.forename: Carsten
authors.initials: C
authors.lastname: Russ
authors.affiliation: BROAD Institute, MIT, Cambridge, MA, 02142, USA.
authors.forename: Chad
authors.initials: C
authors.lastname: Nusbaum
authors.affiliation: BROAD Institute, MIT, Cambridge, MA, 02142, USA.
authors.forename: Qiandong
authors.initials: Q
authors.lastname: Zeng
authors.affiliation: Department of Plant Pathology, North Carolina State University, Raleigh, NC, 27695, USA.
authors.forename: Amanda C
authors.initials: AC
authors.lastname: Saville
authors.affiliation: Department of Plant Pathology, North Carolina State University, Raleigh, NC, 27695, USA.
authors.forename: Rodrigo A
authors.initials: RA
authors.lastname: Olarte
authors.affiliation: Department of Plant Pathology, North Carolina State University, Raleigh, NC, 27695, USA.
authors.forename: Ignazio
authors.initials: I
authors.lastname: Carbone
authors.affiliation: Department of Plant Pathology, North Carolina State University, Raleigh, NC, 27695, USA.
authors.forename: Chia-Hui
authors.initials: CH
authors.lastname: Hu
authors.affiliation: Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Andaine
authors.initials: A
authors.lastname: Seguin-Orlando
authors.affiliation: Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Jose A
authors.initials: JA
authors.lastname: Samaniego
authors.affiliation: Department of Biological Sciences and Department of Statistics, North Carolina State University, Raleigh, NC 27695, USA.
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Thorne
authors.affiliation: Department of Plant Pathology, North Carolina State University, Raleigh, NC, 27695, USA. jean_ristaino@ncsu.edu.
authors.forename: Jean B
authors.initials: JB
authors.lastname: Ristaino
mesh_terms: D005075:Biological Evolution; D002678:Chimera / Q000382:microbiology; D003105:Colombia; D004272:DNA, Mitochondrial / Q000235:genetics; D004484:Ecuador; D054629:Genome, Mitochondrial; D018551:Solanum lycopersicum / Q000382:microbiology; D008928:Mitochondria / Q000235:genetics*; D010568:Peru; D010802:Phylogeny; D058974:Phylogeography; D010838:Phytophthora / Q000145:classification / Q000235:genetics*; D055750:Phytophthora infestans / Q000145:classification / Q000235:genetics*; D010935:Plant Diseases / Q000382:microbiology; D017422:Sequence Analysis, DNA; D011198:Solanum tuberosum / Q000382:microbiology
chemical_list: D004272:DNA, Mitochondrial
keywords: Late blight; Mitochondria; Phylogenetics; Phytophthora 1 c clade