title: Classic biphasic pulmonary blastoma with brain and axillary metastases: a case report with molecular analysis and review of literature.
abstract: Pulmonary blastoma is a rare series of malignant lung tumor, which contains three categories: classic biphasic pulmonary blastoma, pluropulmonary blastoma, and well-differentiated fetal adenocarcinoma. In this study, a 19-year old female suffering with classic biphasic pulmonary blastoma and metastases in brain and axilla was presented with special interest in clinicopathological presentations, immunohistochemical features, and molecular characterizations. However, this case was misdiagnosed initially with small biopsy specimen. Comprehensive management should be used for the treatment of this malignancy.
authors.affiliation: Department of Pathology, West China Hospital, Sichuan University Chengdu, China.
authors.forename: Yingjie
authors.initials: Y
authors.lastname: Xiu
authors.affiliation: Department of Pathology, West China Hospital, Sichuan University Chengdu, China.
authors.forename: Lili
authors.initials: L
authors.lastname: Jiang
authors.affiliation: Department of Pathology, West China Hospital, Sichuan University Chengdu, China.
authors.forename: Weiping
authors.initials: W
authors.lastname: Liu
mesh_terms: D001365:Axilla / Q000473:pathology; D014408:Biomarkers, Tumor / Q000032:analysis; D001932:Brain Neoplasms / Q000556:secondary; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology; D018202:Pulmonary Blastoma / Q000556:secondary*; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor
keywords: Pulmonary blastoma; classic biphasic pulmonary blastoma; metastasis; treatment