title: Depression screening in patients with brain tumors: a review.
abstract: Brain tumor (BT) is often a devastating disease associated with poor prognosis. Depression is a common complication in BT patients that often remains under-recognized and untreated. Implementation of reliable depression screening algorithms in routine neuro-oncology setting could potentially improve recognition of depression. The Hospital Anxiety and Depression scale-Depression subscale and Patient Health Questionnaire-9 demonstrated adequate psychometric properties for depressive disorder screening in glioma patients. Patients screened positive for depression should be referred for detailed psychiatric assessment prior to initiating anti-depressive treatment. Further methodologically rigorous studies investigating psychometric properties of single-item and multiple-item depression scales are urgently warranted. Studies evaluating anti-depressive treatments' efficacy and clinical value of depression biomarkers are important avenues for future research endeavors in BT patients.
authors.affiliation: Neuroscience Institute, Laboratory of Clinical Research, Lithuanian University of Health Sciences, Eiveniu g. 4, LT-50009 Kaunas, Lithuania.
authors.forename: Aiste
authors.initials: A
authors.lastname: Pranckeviciene
authors.forename: Adomas
authors.initials: A
authors.lastname: Bunevicius
mesh_terms: D001932:Brain Neoplasms / Q000150:complications* / Q000523:psychology; D003863:Depression / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D011569:Psychiatric Status Rating Scales; D057566:Self Report; D011795:Surveys and Questionnaires
keywords: brain tumors; depression; diagnostic accuracy; screening