title: New frontiers for encapsulation in the chemical industry.
abstract: Encapsulation of actives comprises an area of exploration undergoing rapid growth in both academic and industrial research settings. Encapsulation processes are employed as a part of product synthesis processes for improved efficiency, enhanced stability, active ingredient compatibility, increased safety, targeted delivery, and novel performance of the end product. Such technical benefits enable producers to offer products with increased formulation complexity, access new markets, differentiate products, and improve compatibility and stability, while meeting consumer demands with improved performance, reduced costs, and new actives. In this review, we highlight several emerging academic areas of encapsulation that we believe have specific relevance to industrial formulation, with a focus on three primary areas: supramolecular encapsulation, aqueous self-assembled systems, and emulsion-based capsules. The goal of this review is to help identify the major challenges facing encapsulation technology adoption in the chemical industry, bringing focus and maximizing the potential value of ongoing research efforts.
authors.affiliation: †Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
authors.forename: Brenda
authors.initials: B
authors.lastname: Andrade
authors.affiliation: ‡Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
authors.forename: Ziyuan
authors.initials: Z
authors.lastname: Song
authors.affiliation: †Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.affiliation: †Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
authors.forename: Steven C
authors.initials: SC
authors.lastname: Zimmerman
authors.affiliation: ‡Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
authors.forename: Jianjun
authors.initials: J
authors.lastname: Cheng
authors.affiliation: †Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Moore
authors.affiliation: §Formulation Science, Corporate Research and Development, The Dow Chemical Company, Midland, Michigan 48667, United States.
authors.forename: Keith
authors.initials: K
authors.lastname: Harris
authors.affiliation: ∥Formulation Science, Corporate Research and Development, The Dow Chemical Company, Collegeville, Pennsylvania 19426, United States.
authors.forename: Joshua S
authors.initials: JS
authors.lastname: Katz
mesh_terms: D002214:Capsules / Q000737:chemistry*; D002617:Chemical Industry / Q000379:methods / Q000639:trends*; D002626:Chemistry, Pharmaceutical / Q000379:methods / Q000639:trends*; D004364:Pharmaceutical Preparations / Q000737:chemistry*
chemical_list: D002214:Capsules; D004364:Pharmaceutical Preparations
keywords: capsule; controlled release; encapsulation; interfacial polymerization; self-assembly; supramolecular interaction; vesicle