title: Influenza vaccines: challenges and solutions.
abstract: Vaccination is the best method for the prevention and control of influenza. Vaccination can reduce illness and lessen severity of infection. This review focuses on how currently licensed influenza vaccines are generated in the U.S., why the biology of influenza poses vaccine challenges, and vaccine approaches on the horizon that address these challenges.
authors.affiliation: Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Katherine
authors.initials: K
authors.lastname: Houser
authors.affiliation: Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: ksubbarao@niaid.nih.gov.
authors.forename: Kanta
authors.initials: K
authors.lastname: Subbarao
mesh_terms: D000956:Antigens, Viral / Q000235:genetics / Q000276:immunology*; D006801:Humans; D007252:Influenza Vaccines / Q000276:immunology* / Q000302:isolation & purification; D007251:Influenza, Human / Q000517:prevention & control*; D009154:Mutation; D009975:Orthomyxoviridae / Q000235:genetics / Q000276:immunology* / Q000502:physiology; D016865:Reassortant Viruses / Q000235:genetics / Q000276:immunology*; D013678:Technology, Pharmaceutical / Q000379:methods* / Q000639:trends; D014481:United States
chemical_list: D000956:Antigens, Viral; D007252:Influenza Vaccines