title: Evaluation of cord blood ischemia modified albumin in normal pregnancies and pre-eclampsia.
abstract: OBJECTIVE
  Pre-eclampsia is associated with ischemia and increased oxidative stress, which may lead to modification of plasma albumin to ischemia modified albumin (IMA).
  
  
  METHODS
  IMA levels were estimated in cord blood of 30 newborns born to pre-eclamptic mothers and compared with 30 normal newborns. IMA was estimated colorimetrically and the results were compared statistically.
  
  
  RESULTS
  The levels of IMA were found to be significantly higher (p < 0.001) in newborns born to pre-eclamptic mothers (0.835 ± 0.02 ABSU) as compared to those born to normal mothers (0.325 ± 0.01 ABSU).
  
  
  CONCLUSIONS
  IMA may act as a marker of ischemia and oxidative stress in newborns delivered to pre-eclamptic mothers.
authors.affiliation: Department of Biochemistry and.
authors.forename: Kiran
authors.initials: K
authors.lastname: Dahiya
authors.forename: Manish Raj
authors.initials: MR
authors.lastname: Kulshrestha
authors.forename: Piyush
authors.initials: P
authors.lastname: Bansal
authors.forename: Veena Singh
authors.initials: VS
authors.lastname: Ghalaut
authors.forename: Rupita
authors.initials: R
authors.lastname: Kulshrestha
authors.forename: Priya
authors.initials: P
authors.lastname: Dahiya
authors.forename: Vasudha
authors.initials: V
authors.lastname: Dhupper
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D007231:Infant, Newborn; D018384:Oxidative Stress; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy / Q000097:blood*; D012709:Serum Albumin; D000075462:Serum Albumin, Human
chemical_list: D015415:Biomarkers; D012709:Serum Albumin; C561522:ischemia-modified albumin; D000075462:Serum Albumin, Human
keywords: Cord blood; Ischemia; Ischemia modified albumin; Oxidative stress; Pre-eclampsia