title: Identification and characterization of the diuretic hormone 31 receptor in the silkworm Bombyx mori.
abstract: The receptor for diuretic hormone 31 (DH31R) was identified in the silkworm Bombyx mori. A heterologous expression system revealed that an orphan G-protein coupled receptor, BNGR-B1, responded to DH31 and upregulated the intracellular cAMP level. DH31R (BNGR-B1) was predominantly expressed in the anterior silk gland, midgut, and ovary, whereas DH31 was predominantly expressed in the central nervous system and midgut.
authors.affiliation: a Department of Integrated Biosciences, Graduate School of Frontier Sciences , The University of Tokyo , Chiba , Japan.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Iga
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kataoka
mesh_terms: D000818:Animals; D012831:Bombyx / Q000235:genetics*; D000242:Cyclic AMP / Q000096:biosynthesis / Q000235:genetics; D019143:Evolution, Molecular; D005786:Gene Expression Regulation; D007301:Insect Hormones / Q000235:genetics* / Q000302:isolation & purification; D019476:Insect Proteins / Q000235:genetics*; D010802:Phylogeny; D043562:Receptors, G-Protein-Coupled / Q000235:genetics*
chemical_list: D007301:Insect Hormones; D019476:Insect Proteins; D043562:Receptors, G-Protein-Coupled; D000242:Cyclic AMP
keywords: Bombyx mori; G-protein coupled receptor; cAMP; diuretic hormone 31