title: Mitochondrial permeability transition pore (MPTP)-dependent and -independent pathways of mitochondrial membrane depolarization, cell shrinkage and microparticle formation during platelet apoptosis.
authors.affiliation: Toronto Platelet Immunobiology Group, St. Michael's Hospital, Toronto, ON, Canada; The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Toronto, ON, Canada.
authors.forename: Armen V
authors.initials: AV
authors.lastname: Gyulkhandanyan
authors.forename: Asuman
authors.initials: A
authors.lastname: Mutlu
authors.forename: John
authors.initials: J
authors.lastname: Freedman
authors.forename: Valery
authors.initials: V
authors.lastname: Leytin
mesh_terms: D017209:Apoptosis / Q000502:physiology*; D001792:Blood Platelets / Q000378:metabolism*; D055252:Cell-Derived Microparticles / Q000378:metabolism*; D006801:Humans; D053078:Membrane Potential, Mitochondrial / Q000502:physiology*; D033681:Mitochondrial Membrane Transport Proteins / Q000378:metabolism*; D051336:Mitochondrial Membranes / Q000378:metabolism*; D000083162:Mitochondrial Permeability Transition Pore
chemical_list: D033681:Mitochondrial Membrane Transport Proteins; D000083162:Mitochondrial Permeability Transition Pore
keywords: apoptosis; depolarization; mitochondria; permeabilization; platelets