title: A sanguineous pleuro pericardial effusion in a patient recently treated with Dabigatran.
abstract: Dabigatran, a direct thrombin inhibitor, is one of the new oral anticoagulants. As more patients receive treatment with Dabigatran, and as the clinical indications for Dabigatran use expand, reporting serious adverse effects is fundamental to future safety assessment. Although patients taking Dabigatran had fewer life-threatening bleeds when compared to Coumadin, those events continue to be reported. We describe, in the same patient, a sanguineous pleuro pericardial effusion that was diagnosed incidentally on a pre-ablation cardiac CT angiography. The diagnosis was made approximately two months after initiating Dabigatran treatment for non-valvular atrial fibrillation in a 63-year-old patient.
authors.affiliation: Staten Island University Hospital Department of Medicine, 475 Seaview Ave, Staten Island, NY 10305, USA. Electronic address: mk_abdullah@hotmail.com.
authors.forename: Mokhtar
authors.initials: M
authors.lastname: Abdallah
authors.affiliation: Staten Island University Hospital Department of Medicine, 475 Seaview Ave, Staten Island, NY 10305, USA.
authors.forename: Tarek
authors.initials: T
authors.lastname: Abdallah
authors.affiliation: Staten Island University Hospital Department of Medicine, 475 Seaview Ave, Staten Island, NY 10305, USA.
authors.forename: Nidal
authors.initials: N
authors.lastname: Abi Rafeh
authors.affiliation: Staten Island University Hospital Department of Medicine, 475 Seaview Ave, Staten Island, NY 10305, USA.
authors.forename: Georges
authors.initials: G
authors.lastname: Khoueiry
authors.affiliation: Staten Island University Hospital Department of Medicine, 475 Seaview Ave, Staten Island, NY 10305, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Abouyassine
authors.affiliation: Staten Island University Hospital Department of Medicine, 475 Seaview Ave, Staten Island, NY 10305, USA.
authors.forename: Michel
authors.initials: M
authors.lastname: Chalhoub
authors.affiliation: Staten Island University Hospital Department of Medicine, 475 Seaview Ave, Staten Island, NY 10305, USA.
authors.forename: Dany
authors.initials: D
authors.lastname: Elsayegh
authors.affiliation: Staten Island University Hospital Department of Medicine, 475 Seaview Ave, Staten Island, NY 10305, USA.
authors.forename: Louis
authors.initials: L
authors.lastname: Sasso
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy; D017115:Catheter Ablation; D000069604:Dabigatran / Q000009:adverse effects* / Q000627:therapeutic use; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged; D010490:Pericardial Effusion / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000925:Anticoagulants; D000069604:Dabigatran
keywords: Anticoagulation; Atrial fibrillation; Dabigatran; Hemopericardium; Pleural effusion