title: Linchpin dienes: key building-blocks in the synthesis of polyenic frameworks.
abstract: A myriad of biologically active products incorporates polyenic frameworks. Among the syntheses developed to access these moieties, metal-catalyzed cross-couplings emerged as reactions of choice especially due to their high stereoselectivity. Particularly, the use of bifunctionalized compounds (linchpin reagents) allows a fast, modular and efficient access to polyenic chains. In this review, we will focus on the preparation of bifunctionalized dienes and on their utilization in the synthesis of polyenes.
authors.affiliation: Laboratoire de Chimie Organique, Institute of Chemistry, Biology and Innovation (CBI), UMR 8231, ESPCI ParisTech/CNRS/PSL Research University, 10, rue Vauquelin, 75231 Paris Cedex, France. Janine.cossy@espci.fr.
authors.forename: J
authors.initials: J
authors.lastname: Cornil
authors.forename: A
authors.initials: A
authors.lastname: Guérinot
authors.forename: J
authors.initials: J
authors.lastname: Cossy
mesh_terms: D001895:Boron / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D006859:Hydrogen / Q000737:chemistry; D011090:Polyenes / Q000138:chemical synthesis* / Q000737:chemistry; D012825:Silicon / Q000737:chemistry; D014001:Tin / Q000737:chemistry
chemical_list: D011090:Polyenes; D014001:Tin; D006859:Hydrogen; D001895:Boron; D012825:Silicon