title: Wound bed preparation for ischemic diabetic foot ulcer.
abstract: OBJECTIVE
  This study is to evaluate the effect of allograft skin on wound angiogenesis and wound bed preparation of ischemic diabetic foot ulcer.
  
  
  METHODS
  A total of 60 cases of patients with diabetic foot ulcer were randomly divided into the experimental group (n = 30) and the control group (n = 30). After debridement, in the experimental group, allograft skin was used to cover the wound while in the control group, vaseline and gauze was used to cover the wound. The wound was opened and dressed at 3, 5, 7, 14 days after operation and the growth condition of the granulation tissue was observed and recorded.
  
  
  RESULTS
  The wound bed preparation time of the experimental group was 14.37 ± 1.06 days, compared with the control group 25.99 ± 4.03 days, there was statistically significant difference (t = 14.78, P < 0.0001). The mean cure time of the experimental group was 32 ± 1.93 days and this time was significantly shortened than the control group 39.73 ± 2.55 days (t = 12.521, P < 0.01).
  
  
  CONCLUSIONS
  Allogeneic skin has a protective effect on the wound and could promote vascularization of ischemic diabetic foot ulcer and shorten the wound bed preparation time and treatment cycle.
authors.affiliation: Department of Burns, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 83000, P.R. China.
authors.forename: Zhaoxin
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Burns, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 83000, P.R. China.
authors.forename: Lei
authors.initials: L
authors.lastname: Lv
authors.affiliation: Department of Vascular Surgery, People's Hospital of Xinjiang Uygur Autonomous Region Urumqi 83000, P.R. China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Guan
keywords: Diabetic foot ulcers; lower limb ischemic disease; wound bed preparation