title: Synthesis of aryl anti-vicinal diamines via aza-Brook rearrangement-initiated nucleophilic addition of α-silylamines to imines.
abstract: An efficient protocol is described for the synthesis of vicinal diamines via aza-Brook rearrangement-initiated nucleophilic addition of α-silylamines to imines. Various symmetrical and unsymmetrical aryl diamine derivatives were prepared in moderate to high yields with high anti/syn diastereoselectivity.
authors.forename: Chao-Yang
authors.initials: CY
authors.lastname: Lin
authors.affiliation: ‡Department of Chemistry and Applied Chemistry, Changji University, Changji 831100, China.
authors.forename: Zhao
authors.initials: Z
authors.lastname: Sun
authors.forename: Yan-Jun
authors.initials: YJ
authors.lastname: Xu
authors.affiliation: ‡Department of Chemistry and Applied Chemistry, Changji University, Changji 831100, China.
authors.forename: Chong-Dao
authors.initials: CD
authors.lastname: Lu
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D003959:Diamines / Q000138:chemical synthesis* / Q000737:chemistry; D007097:Imines / Q000737:chemistry*; D015394:Molecular Structure; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D003959:Diamines; D007097:Imines; D012821:Silanes