title: Plant hemoglobin participation in cell fate determination.
abstract: Plant hemoglobins (Hbs) have been identified as master regulators in determining the developmental fate of specific cells during maize embryogenesis. Whether an embryogenic cell lives or undergoes programmed cell death (PCD) is modulated by Hbs, through their tight interactions with nitric oxide (NO) and auxin. During maize embryogenesis, Hb-suppressing cells accumulate NO, are depleted of auxin, and are committed to die. We propose that Hbs control cell fate by regulating NO and auxin homeostasis, and that this type of mechanism may influence other hormonal responses modulating plant behavior during development and stress conditions.
authors.affiliation: a Department of Plant Science; University of Manitoba; Winnipeg, MB Canada.
authors.forename: Shuanglong
authors.initials: S
authors.lastname: Huang
authors.forename: Robert D
authors.initials: RD
authors.lastname: Hill
authors.forename: Claudio
authors.initials: C
authors.lastname: Stasolla
mesh_terms: D017209:Apoptosis; D002454:Cell Differentiation; D018506:Gene Expression Regulation, Plant; D006454:Hemoglobins / Q000378:metabolism*; D007210:Indoleacetic Acids / Q000378:metabolism*; D009569:Nitric Oxide / Q000378:metabolism*; D063245:Plant Development; D010937:Plant Growth Regulators / Q000378:metabolism; D010940:Plant Proteins / Q000378:metabolism; D012639:Seeds / Q000254:growth & development / Q000378:metabolism; D013312:Stress, Physiological; D003313:Zea mays / Q000196:embryology / Q000378:metabolism
chemical_list: D006454:Hemoglobins; D007210:Indoleacetic Acids; D010937:Plant Growth Regulators; D010940:Plant Proteins; D009569:Nitric Oxide
keywords: cell fate; embryogenesis; hemoglobin; hormone; nitric oxide