title: Evaluation of fully biodegradable nasal packings in functional endoscopic sinus surgery – a multi-centre study.
abstract: OBJECTIVE
  This work was to compare an innovative solution, i.e. a fully biodegradable nasal packing Nasopore®, with a traditional one, in the aftercare of patients subjected to functional endoscopic sinus surgery.
  
  
  METHODS
  Prospective, blinded study with sequential enrollment conducted at three study centres. One of the investigators evaluated during surgery the level of bleeding in each of the nasal cavities and at the end of surgery he applied the test packing, the biodegradable dressing Nasopore®, to one randomly chosen nasal cavity, and a control packing to the other one. The other investigator removed during aftercare the control packing and conducted the follow-up. During the control visits (24-48 hours, 10 and 30 days post-op.) the subjects evaluated their headache, pain in the nose, pressure in the forehead as well as their nasal obstruction.
  
  
  RESULTS
  A total of 39 women and 44 men at the age of 47 years on average (min. 19, max. 82) were qualified for the study. The largest differences between different types of nasal dressings were observed with regard to reduction of nasal obstruction in the fist 10 days after surgery (P<0.005). In relation to the pain in the area of the head and nose as well the pressure in the forehead on every visit, better outcomes were observed for the test dressing. Statistical difference (P<0.05) was observed on the fist follow-up visit for the headache and pressure in the forehead as well as on the fist and second visit for the pain in the nose.
  
  
  CONCLUSIONS
  The fully biodegradable nasal dressing Nasopore® may constitute significant improvement and facilitation of aftercare in functional endoscopic sinus surgery while increasing the patients' satisfaction and lowering the postoperative discomfort.
authors.affiliation: Klinika Otolaryngologii i Onkologii Laryngologicznej z Klinicznym Oddziałem Chirurgii Czaszkowo-Szczękowo-Twarzowej Centralnego Szpitala Klinicznego MON Wojskowego Instytutu Medycznego w Warszawie.
authors.forename: Dariusz
authors.initials: D
authors.lastname: Jurkiewicz
authors.affiliation: Klinika Otolaryngologii Uniwersyteckiego Szpitala Klinicznego w Białymstoku.
authors.forename: Henryk
authors.initials: H
authors.lastname: Kaźmierczak
authors.affiliation: Klinika Otolaryngologii i Onkologii Laryngologicznej Szpitala Uniwersyteckiego im. dr Antoniego Jurasza w Bydgoszczy.
authors.forename: Marek
authors.initials: M
authors.lastname: Rogowski
authors.affiliation: Klinika Otolaryngologii Uniwersyteckiego Szpitala Klinicznego w Białymstoku.
authors.forename: Paweł K
authors.initials: PK
authors.lastname: Burduk
authors.affiliation: Klinika Otolaryngologii i Onkologii Laryngologicznej z Klinicznym Oddziałem Chirurgii Czaszkowo-Szczękowo-Twarzowej Centralnego Szpitala Klinicznego MON Wojskowego Instytutu Medycznego w Warszawie.
authors.forename: Barbara
authors.initials: B
authors.lastname: Gałusza
authors.affiliation: Klinika Otolaryngologii Uniwersyteckiego Szpitala Klinicznego w Białymstoku.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Kaźmierczak
authors.affiliation: Klinika Otolaryngologii i Onkologii Laryngologicznej Szpitala Uniwersyteckiego im. dr Antoniego Jurasza w Bydgoszczy.
authors.forename: Bartosz
authors.initials: B
authors.lastname: Piszczatowski
authors.affiliation: Klinika Otolaryngologii i Onkologii Laryngologicznej Szpitala Uniwersyteckiego im. dr Antoniego Jurasza w Bydgoszczy.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Różańska
authors.affiliation: Klinika Otolaryngologii i Onkologii Laryngologicznej z Klinicznym Oddziałem Chirurgii Czaszkowo-Szczękowo-Twarzowej Centralnego Szpitala Klinicznego MON Wojskowego Instytutu Medycznego w Warszawie.
authors.forename: Rafał
authors.initials: R
authors.lastname: Sienicki
authors.affiliation: Klinika Otolaryngologii i Onkologii Laryngologicznej z Klinicznym Oddziałem Chirurgii Czaszkowo-Szczękowo-Twarzowej Centralnego Szpitala Klinicznego MON Wojskowego Instytutu Medycznego w Warszawie.
authors.forename: Kornel
authors.initials: K
authors.lastname: Szczygielski
authors.affiliation: Klinika Otolaryngologii Uniwersyteckiego Szpitala Klinicznego w Białymstoku.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Wierzchowska
authors.affiliation: Medicus Aparatura i Instrumenty Medyczne Sp. z o. o. sp. k.
authors.forename: Joanna
authors.initials: J
authors.lastname: Kuśmierczyk
mesh_terms: D020341:Absorbable Implants; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004311:Double-Blind Method; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011140:Polyurethanes / Q000008:administration & dosage*; D019106:Postoperative Hemorrhage / Q000517:prevention & control*; D011446:Prospective Studies; D012852:Sinusitis / Q000601:surgery*; D016896:Treatment Outcome; D014945:Wound Healing; D055815:Young Adult
chemical_list: D011140:Polyurethanes; C028279:polyurethane foam