title: Sublingual immunotherapy in children and its potential beneficial collateral effect on respiratory tract infections.
abstract: Although directed to the control of allergic symptoms, a possible effect of sublingual immunotherapy (SLIT) on susceptibility to infections has been hypothesized. Two hundred sixty-five children aged between 3 and 4 years of age affected by allergic rhinitis completed a 6 year prospective case-control study. One hundred forty-three children after 2 years of SLIT reported a lower prevalence of respiratory tract infections when compared to children not undergoing SLIT.
authors.affiliation: Department of Pediatrics, Sapienza University of Rome , Rome , Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Occasi
authors.forename: Giovanna
authors.initials: G
authors.lastname: De Castro
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Zicari
authors.forename: Luciana
authors.initials: L
authors.lastname: Indinnimeo
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Tancredi
authors.forename: Marzia
authors.initials: M
authors.lastname: Duse
mesh_terms: D000286:Administration, Sublingual; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000276:immunology / Q000628:therapy*; D065631:Rhinitis, Allergic / Q000276:immunology / Q000628:therapy*; D063729:Sublingual Immunotherapy / Q000379:methods*; D016896:Treatment Outcome
keywords: Antibiotics; Children; Respiratory infections; Sublingual immunotherapy