title: meso-Methylhydroxy BODIPY: a scaffold for photo-labile protecting groups.
abstract: Here, we show that by installing a meso-methylhydroxy moiety, the boron dipyrromethene (BODIPY) scaffold can be converted into an efficient caging group, removable by green light. We describe caging and uncaging of important chemical functionalities and demonstrate green light mediated control over biological processes in cultured cell lines and neurons.
authors.affiliation: Department of Molecular Biology and Ecology of Plants, Life Sciences Faculty, Tel-Aviv University, Ramat Aviv, Tel-Aviv 6997801, Israel. royweinstain@post.tau.ac.il.
authors.forename: Naama
authors.initials: N
authors.lastname: Rubinstein
authors.forename: Pei
authors.initials: P
authors.lastname: Liu
authors.forename: Evan W
authors.initials: EW
authors.lastname: Miller
authors.forename: Roy
authors.initials: R
authors.lastname: Weinstain
mesh_terms: D001896:Boron Compounds / Q000737:chemistry* / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D008027:Light; D009474:Neurons / Q000187:drug effects / Q000528:radiation effects; D061848:Optical Imaging; D017319:Photosensitizing Agents / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D017319:Photosensitizing Agents; D002118:Calcium