title: Incidental lung volume reduction following fulminant pulmonary hemorrhage in a patient with severe emphysema.
abstract: Endoscopic lung volume reduction is an emerging technique meant to improve lung function parameters, quality of life, and exercise tolerance in patients with severe lung emphysema. This is the first report of lung volume reduction by autologous blood in a patient with non-bullous lung emphysema. A 74-year-old woman with heterogeneous lung emphysema developed accidentally diffuse lobar bleeding immediately after valve placement. Due to persistent hemorrhage, the valves had to be removed shortly thereafter. Despite extraction of the valves, respiratory function of the patient improved rapidly indicated also by a drop in the COPD assessment test questionnaire, 3 months later. This was consistent with both improvement of lung function tests and six-minute walking test.
authors.affiliation: Internal Medicine II, University of Tuebingen, Otfried Müller Str. 10, 72076, Tübingen, Germany.
authors.forename: Juergen
authors.initials: J
authors.lastname: Hetzel
authors.forename: Werner
authors.initials: W
authors.lastname: Spengler
authors.forename: Marius
authors.initials: M
authors.lastname: Horger
authors.forename: Michael
authors.initials: M
authors.lastname: Boeckeler
mesh_terms: D000368:Aged; D001999:Bronchoscopy / Q000009:adverse effects* / Q000295:instrumentation; D020878:Device Removal; D005260:Female; D006469:Hemoptysis / Q000209:etiology; D006489:Hemostatic Techniques; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D008176:Lung Volume Measurements; D019106:Postoperative Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D011656:Pulmonary Emphysema / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D020127:Recovery of Function; D012086:Reoperation; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome