title: Contribution of ABA UDP-glucosyltransferases in coordination of ABA biosynthesis and catabolism for ABA homeostasis.
abstract: The phytohormone abscisic acid (ABA) plays a crucial role in numerous aspects of plant growth and environmental stress responses. Endogenous ABA levels are regulated by a balance between its biosynthetic and catabolic activities. This balance may occur at multiple levels and includes the expression of genes involved in these processes. ABA UDP-glucosyltransferase (UGT), the major player in the ABA conjugation pathway, has been shown to have a marginal effect on free ABA levels. However, recent studies provide new insight into the importance of the ABA conjugation pathway in contributing to the control of ABA homeostasis. Gain-of-function and loss-of-function mutant analyses have revealed that UGT71B6, an ABA UGT, and its 2 closely related homologs, UGT71B7 and UGT71B8, play a crucial role in ABA homeostasis and in adaptation to various abiotic stresses.
authors.affiliation: a Division of Integrative Biosciences and Biotechnology; Pohang University of Science and Technology; Pohang, Korea.
authors.forename: Ting
authors.initials: T
authors.lastname: Dong
authors.forename: Inhwan
authors.initials: I
authors.lastname: Hwang
mesh_terms: D000040:Abscisic Acid / Q000378:metabolism*; D000222:Adaptation, Physiological; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D005964:Glucosyltransferases / Q000378:metabolism*; D006706:Homeostasis; D010937:Plant Growth Regulators / Q000378:metabolism; D013312:Stress, Physiological
chemical_list: D029681:Arabidopsis Proteins; D010937:Plant Growth Regulators; D000040:Abscisic Acid; D005964:Glucosyltransferases
keywords: ABA UDP-glucosyltransferases; ABA catabolism; ABA homeostasis; abiotic stress; coordination of ABA metabolic pathways