title: Efficacy of laparoscopic adenomyomectomy using double-flap method for diffuse uterine adenomyosis.
abstract: BACKGROUND
  Adenomyomectomy has recently been considered the priority option for the treatment of adenomyosis, however, the surgical efficacy and modes are still debated. We aimed to evaluate the efficacy of laparoscopic adenomyomectomy using a double-flap method for the treatment of uterine diffuse adenomyosis when compared with conventional laparoscopic adenomyomectomy.
  
  
  METHODS
  Laparoscopic adenomyomectomy using the conventional method (group A, n = 48) and the double-flap method (group B, n = 46) to treat diffuse uterine adenomyosis, respectively. Visual analog scale (VAS), menstrual amount, serum CA125 levels, and uterine volume were comparatively analyzed in both groups.
  
  
  RESULTS
  The VAS scores, menstrual amount, serum CA125 levels, and uterine volume at 12 or 24 months after surgery significantly reduced in group B than in group A (P < 0.05); these parameters were statistically decreased in both groups after surgery compared with those obtained before surgery (P < 0.001). Moreover, serum CA125 levels and uterine volume at six months of follow up were significantly lower in group B than in group A (P < 0.01). In addition, blood loss during surgery was similar in groups A and B (P > 0.05), although the operative time was significantly longer in group B than that in group A (P < 0.05).
  
  
  CONCLUSIONS
  Laparoscopic adenomyomectomy using the double-flap method may be an effective technique to treat uterine diffuse adenomyosis.
authors.affiliation: The Department of Gynecology, Women's Hospital, Zhejiang University School of Medicine, 1 Xueshi Road, Hangzhou, Zhejiang, 310006, P. R. China, huangxiufeng73@163.com.
authors.forename: Xiufeng
authors.initials: X
authors.lastname: Huang
authors.forename: Qiongshi
authors.initials: Q
authors.lastname: Huang
authors.forename: Shuyi
authors.initials: S
authors.lastname: Chen
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Kaiqing
authors.initials: K
authors.lastname: Lin
authors.forename: Xinmei
authors.initials: X
authors.lastname: Zhang
mesh_terms: D062788:Adenomyosis / Q000150:complications / Q000601:surgery*; D000328:Adult; D004412:Dysmenorrhea / Q000209:etiology; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D008595:Menorrhagia / Q000209:etiology; D009215:Myometrium / Q000601:surgery*; D013524:Surgical Flaps; D016896:Treatment Outcome