title: Severe microphthalmos with cyst and unusually huge dermolipoma.
abstract: OBJECTIVE
  The purpose of this study was to report an unusual case of severe microphthalmos, together with an orbital cyst and huge ocular surface dermolipoma.
  
  
  METHODS
  This is a clinical report relating clinical features as well as imaging and histopathologic findings, along with surgical management of the patient.
  
  
  RESULTS
  A 5-month-old Chinese male infant was referred, with 2 large masses in the left eye that were present since birth. Ocular examination results revealed a complete absence of any eye structures in the left orbit. In its place were 2 large masses between the left upper and lower palpebral fissure. One was a 3 × 3 × 2.5-cm spherical red tumor with a smooth surface. The other was a large solid spherical tumor, 4 × 4 × 5 cm, covered with normal skin located in the temporal region and attached to the red mass by a pedicle. Orbital magnetic resonance imaging examination findings confirmed that no eye structures were present in the left orbit. However, a cystic lesion was found in the left orbit, with a low signal on T1-weighted imaging and high signal on T2-weighted imaging, and another huge spherical heterogeneous mass was located "outside" the left orbit. Anterior orbitotomy by conjunctival incision was performed under general anesthesia. A spherical cystic mass of 1.5 × 1.5 × 1.6 cm, a small eye of 0.7 × 0.7 × 0.6 cm, and a huge dermolipoma were removed completely. Pathologic examination results confirmed the diagnosis of severe microphthalmos, together with orbital dermoid cyst and dermolipoma.
  
  
  CONCLUSIONS
  This rare case demonstrates that severe microphthalmos with a cyst may be completely covered by conjunctiva and associated with an unusually huge dermolipoma.
authors.affiliation: From the *The State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou; †Department of Ophthalmology, The First Hospital of Putian City, Fujian Province, the People's Republic of China.
authors.forename: Weidong
authors.initials: W
authors.lastname: Li
authors.forename: Ping
authors.initials: P
authors.lastname: Zhang
authors.forename: Qiwen
authors.initials: Q
authors.lastname: Chen
authors.forename: Xuelian
authors.initials: X
authors.lastname: Ye
authors.forename: Jianqun
authors.initials: J
authors.lastname: Li
authors.forename: Jianhua
authors.initials: J
authors.lastname: Yan
mesh_terms: D003884:Dermoid Cyst / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007223:Infant; D008067:Lipoma / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008850:Microphthalmos / Q000175:diagnosis*; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000601:surgery