title: Diagnostic accuracy of cone-beam computed tomography in the evaluation of chronic rhinosinusitis.
abstract: BACKGROUND
  This study assessed the agreement of cone-beam computed tomography (CBCT) scan and sinus endoscopy findings and attempted to find a diagnostic accuracy of CBCT in patients with chronic rhinosinusitis (CRS).
  
  
  METHODS
  Forty-two patients with CRS referred to the Aria and 22 Bahman Hospitals in Mashhad, Iran, during the year 2011 were included in this cross-sectional study. Paranasal sinus CBCT scanning and endoscopy were performed in all patients. The sensitivity, specificity, positive and negative predictive values (PPV and NPV), and accuracy of CBCT were determined, and the agreement between CBCT and endoscopy findings was evaluated.
  
  
  RESULTS
  In most of our findings, except for infundibulum thickening, there was a strong agreement between CBCT and paranasal sinus endoscopy, with a kappa coefficient >0.80 (p < 0.05). The sensitivity, specificity, PPV, NPV, and accuracy of CBCT were >80% for most of the findings, except for infundibulum thickening and septal deviation.
  
  
  CONCLUSIONS
  CBCT has nearly the same diagnostic accuracy as sinus endoscopy. The accuracy of CBCT scanning is high, and CBCT findings are well correlated with sinus endoscopy findings. Considering its high accuracy and lower costs and radiation doses, CBCT may be a proper alternative method for diagnostic sinus endoscopy in the assessment of CRS in patients with a contraindication for sinus endoscopy.
authors.forename: Ramin
authors.initials: R
authors.lastname: Zojaji
authors.forename: Masoud
authors.initials: M
authors.lastname: Naghibzadeh
authors.forename: Morteza
authors.initials: M
authors.lastname: Mazloum Farsi Baf
authors.forename: Sirous
authors.initials: S
authors.lastname: Nekooei
authors.forename: Behrokh
authors.initials: B
authors.lastname: Bataghva
authors.forename: Sara
authors.initials: S
authors.lastname: Noorbakhsh
mesh_terms: D000328:Adult; D002908:Chronic Disease; D054893:Cone-Beam Computed Tomography; D003430:Cross-Sectional Studies; D004724:Endoscopy; D005260:Female; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012220:Rhinitis / Q000175:diagnosis*; D012852:Sinusitis / Q000175:diagnosis*; D055815:Young Adult