title: Copper-catalyzed asymmetric allylation of chiral N-tert-butanesulfinyl imines: dual stereocontrol with nearly perfect diastereoselectivity.
abstract: Copper-catalyzed asymmetric allylation of chiral N-tert-butanesulfinyl imines has been described. Dual stereocontrol, through the combination of a chiral auxiliary and a chiral copper complex, has played an important role in achieving the nearly perfect diastereoselectivities (all dr > 99 : 1), especially for ketimine substrates.
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, 75 Daxue Road, Zhengzhou, Henan 450052, China. jctao@zzu.edu.cn.
authors.forename: Yi-Shuang
authors.initials: YS
authors.lastname: Zhao
authors.forename: Qiang
authors.initials: Q
authors.lastname: Liu
authors.forename: Ping
authors.initials: P
authors.lastname: Tian
authors.forename: Jing-Chao
authors.initials: JC
authors.lastname: Tao
authors.forename: Guo-Qiang
authors.initials: GQ
authors.lastname: Lin
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007097:Imines / Q000737:chemistry; D009570:Nitriles / Q000737:chemistry; D013237:Stereoisomerism; D013452:Sulfonium Compounds / Q000737:chemistry*
chemical_list: D000475:Alkenes; D007097:Imines; C481933:N-tert-butanesulfinylimino ester; D009570:Nitriles; D013452:Sulfonium Compounds; C542835:ketimine; D003300:Copper