title: [The level of lipid peroxidation in milk replacer formulas for initial feeding of infants].
abstract: The products of lipids oxidation: peroxides, hydroxides, aldehydes, ketones, esters, alcohols and others show harmful activity against human organism. Presence of the compounds in baby's and children's food creates potential health hazard. Many of them cause infant's and children's diarrhoea, also, negatively influence development of nervous system, show cytotoxic, mutagenic and cancerogenic activity (e.g. malonicdialdehyde, 4-hydroxynonenal and others).
  
  
  OBJECTIVE
  The aim of the work was to assess the level of lipids peroxidation in milk substitute preparations for initial stage baby feeding, before their end of shelf-life.
  
  
  METHODS
  The level of lipids peroxidation measured as TBARS (thiobarbituric acid reactive substances) concentrations was determined in 6 available on the Polish market milk substitute infant formulas. The determinations was carried out before the end of the shelf-life after 1,2,3,6,9 and 12 months after purchase. The level of lipid peroxidation was also determined after 3-4 and 21 days post opening.
  
  
  RESULTS
  TBARS content in the infants food ready to be eaten depended on the time of preparation storage. The highest level of lipids peroxidation was observed in all the studied food after 12 months of storage and after 21 days after opening of the hermetical wrapping. Various level of lipids peroxidation in milk substitutes for infant nutrition resulted from different amounts and quality of plant oils used in production (different content of mono- and polyunsaturated fatty acids, presence of lack of linoleic and α-linolenic acids).
authors.affiliation: Department of Biochemistry, I Faculty of Medicine, Medical University of Warsaw, Poland.
authors.forename: Hanna
authors.initials: H
authors.lastname: Czeczot
authors.affiliation: Department of Dairy Science and Quality Management, University of Warmia and Mazury in Olsztyn, Poland.
authors.forename: Grażyna
authors.initials: G
authors.lastname: Cichosz
authors.affiliation: Department of Dairy Science and Quality Management, University of Warmia and Mazury in Olsztyn, Poland.
authors.forename: Adam
authors.initials: A
authors.lastname: Ambroziak
mesh_terms: D005504:Food Analysis / Q000379:methods*; D006801:Humans; D007223:Infant; D007225:Infant Food / Q000032:analysis; D041943:Infant Formula / Q000737:chemistry*; D007231:Infant, Newborn; D015227:Lipid Peroxidation; D011044:Poland; D017392:Thiobarbituric Acid Reactive Substances / Q000032:analysis*
chemical_list: D017392:Thiobarbituric Acid Reactive Substances
keywords: human milk; infant formulae; level of peroxidation lipids; malondialdehyde (MDA); thiobarbituric acid reactive substances (TBARS)