title: The Chlamydomonas heat stress response.
abstract: Heat waves occurring at increased frequency as a consequence of global warming jeopardize crop yield safety. One way to encounter this problem is to genetically engineer crop plants toward increased thermotolerance. To identify entry points for genetic engineering, a thorough understanding of how plant cells perceive heat stress and respond to it is required. Using the unicellular green alga Chlamydomonas reinhardtii as a model system to study the fundamental mechanisms of the plant heat stress response has several advantages. Most prominent among them is the suitability of Chlamydomonas for studying stress responses system-wide and in a time-resolved manner under controlled conditions. Here we review current knowledge on how heat is sensed and signaled to trigger temporally and functionally grouped sub-responses termed response elements to prevent damage and to maintain cellular homeostasis in plant cells.
authors.affiliation: Molecular Biotechnology & Systems Biology, TU Kaiserslautern, Paul-Ehrlich-Straße 23, 67663, Kaiserslautern, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Schroda
authors.affiliation: Molecular Biotechnology & Systems Biology, TU Kaiserslautern, Paul-Ehrlich-Straße 23, 67663, Kaiserslautern, Germany.
authors.forename: Dorothea
authors.initials: D
authors.lastname: Hemme
authors.affiliation: Molecular Biotechnology & Systems Biology, TU Kaiserslautern, Paul-Ehrlich-Straße 23, 67663, Kaiserslautern, Germany.
authors.forename: Timo
authors.initials: T
authors.lastname: Mühlhaus
mesh_terms: D002118:Calcium / Q000378:metabolism; D059447:Cell Cycle Checkpoints; D002462:Cell Membrane / Q000378:metabolism; D002696:Chlamydomonas / Q000166:cytology / Q000502:physiology*; D016825:Chlamydomonas reinhardtii / Q000502:physiology; D018869:Heat-Shock Response / Q000502:physiology*; D059828:Plant Cells / Q000502:physiology; D010940:Plant Proteins / Q000378:metabolism; D011494:Protein Kinases / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D010940:Plant Proteins; D011494:Protein Kinases; D002118:Calcium
keywords: Chlamydomonas reinhardtii; cell cycle; compatible solutes; lipid bodies; membrane fluidity; molecular chaperones; photosynthesis