title: Expert consensus document: Mind the gaps—advancing research into short-term and long-term neuropsychological outcomes of youth sports-related concussions.
abstract: Sports-related concussions and repetitive subconcussive exposure are increasingly recognized as potential dangers to paediatric populations, but much remains unknown about the short-term and long-term consequences of these events, including potential cognitive impairment and risk of later-life dementia. This Expert Consensus Document is the result of a 1-day meeting convened by Safe Kids Worldwide, the Alzheimer's Drug Discovery Foundation, and the Andrews Institute for Orthopaedics and Sports Medicine. The goal is to highlight knowledge gaps and areas of critically needed research in the areas of concussion science, dementia, genetics, diagnostic and prognostic biomarkers, neuroimaging, sports injury surveillance, and information sharing. For each of these areas, we propose clear and achievable paths to improve the understanding, treatment and prevention of youth sports-related concussions.
authors.affiliation: Alzheimer's Drug Discovery Foundation, 57 West 57th Street, Suite 904, New York, NY 10019, USA.
authors.forename: Aaron J
authors.initials: AJ
authors.lastname: Carman
authors.affiliation: Safe Kids Worldwide, Inc., USA.
authors.forename: Rennie
authors.initials: R
authors.lastname: Ferguson
authors.affiliation: Boston University Medical Center, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Cantu
authors.affiliation: University of Colorado at Denver, USA.
authors.forename: R Dawn
authors.initials: RD
authors.lastname: Comstock
authors.affiliation: Alzheimer's Drug Discovery Foundation, 57 West 57th Street, Suite 904, New York, NY 10019, USA.
authors.forename: Penny A
authors.initials: PA
authors.lastname: Dacks
authors.affiliation: University of Virginia School of Medicine, USA.
authors.forename: Steven T
authors.initials: ST
authors.lastname: DeKosky
authors.affiliation: Icahn School of Medicine at Mount Sinai, USA.
authors.forename: Sam
authors.initials: S
authors.lastname: Gandy
authors.affiliation: Metro Orthopedics &Sports Therapy, USA.
authors.forename: James
authors.initials: J
authors.lastname: Gilbert
authors.affiliation: Andrews Institute for Orthopaedics and Sports Medicine, USA.
authors.forename: Chad
authors.initials: C
authors.lastname: Gilliland
authors.affiliation: George Washington School of Medicine, USA.
authors.forename: Gerard
authors.initials: G
authors.lastname: Gioia
authors.affiliation: University of California, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Giza
authors.affiliation: Stanford Center on Longevity, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Greicius
authors.affiliation: National Collegiate Athletic Association, USA.
authors.forename: Brian
authors.initials: B
authors.lastname: Hainline
authors.affiliation: Banyan Biomarkers, USA.
authors.forename: Ronald L
authors.initials: RL
authors.lastname: Hayes
authors.affiliation: Alzheimer's Association, USA.
authors.forename: James
authors.initials: J
authors.lastname: Hendrix
authors.affiliation: Burke Rehabilitation Hospital, USA.
authors.forename: Barry
authors.initials: B
authors.lastname: Jordan
authors.affiliation: CrowdOptic, Inc., USA.
authors.forename: James
authors.initials: J
authors.lastname: Kovach
authors.affiliation: Alzheimer's Drug Discovery Foundation, 57 West 57th Street, Suite 904, New York, NY 10019, USA.
authors.forename: Rachel F
authors.initials: RF
authors.lastname: Lane
authors.affiliation: Children's Hospital, Harvard Medical School, USA.
authors.forename: Rebekah
authors.initials: R
authors.lastname: Mannix
authors.affiliation: The Hastings Center, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Murray
authors.affiliation: Norton Healthcare, University of Kentucky, USA.
authors.forename: Tad
authors.initials: T
authors.lastname: Seifert
authors.affiliation: Alzheimer's Drug Discovery Foundation, 57 West 57th Street, Suite 904, New York, NY 10019, USA.
authors.forename: Diana W
authors.initials: DW
authors.lastname: Shineman
authors.affiliation: Novant Health Sports Medicine, USA.
authors.forename: Eric
authors.initials: E
authors.lastname: Warren
authors.affiliation: Baylor College of Medicine, USA.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Wilde
authors.affiliation: Baylor College of Medicine, USA.
authors.forename: Huntington
authors.initials: H
authors.lastname: Willard
authors.affiliation: Alzheimer's Drug Discovery Foundation, 57 West 57th Street, Suite 904, New York, NY 10019, USA.
authors.forename: Howard M
authors.initials: HM
authors.lastname: Fillit
mesh_terms: D000818:Animals; D001265:Athletic Injuries; D015415:Biomarkers; D001924:Brain Concussion / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology* / Q000517:prevention & control; D003072:Cognition Disorders / Q000209:etiology; D003704:Dementia / Q000209:etiology; D015600:Glasgow Coma Scale; D006801:Humans; D019636:Neurodegenerative Diseases / Q000209:etiology; D013178:Sports Medicine / Q000639:trends*
chemical_list: D015415:Biomarkers