title: Effect of Scolopendrid Calculus Bovis-Fel Uris- Moschus Bee Venom and Sweet Bee Venom on Regional Cerebral Blood Flow after Pharmacopuncture to GV16 Pungbu and GB20 Pungji in Rat.
abstract: OBJECTIVE
  This study was designed to investigate the effect of four pharmacopuncture drugs (scolopendrid, Calculus Bovis-Fel Uris-Moschus (BUM), bee venom 25%, and sweet bee venom 10%) on the cerebral hemodynamics, including changes in the regional cerebral blood flow (rCBF) and in the mean arterial blood pressure (MABP).
  
  
  METHODS
  The changes in the rCBF and the MABP were determined by using a laser-Doppler flowmeter and a pressure transducer, respectively.
  
  
  RESULTS
  Scolopendrid (0.3 ml, 1 ml/kg) caused no significant changes in the rCBF and the MABP, whereas BUM (0.3 ml, 1 ml/kg) decreased the rCBF and the MABP, bee venom 25% (0.3 ml, 1 ml/kg) increased the rCBF and lowered the MABP, and sweet bee venom 10% (0.3 ml, 1 ml/kg) increased the rCBF and had no significant effect on the MABP.
  
  
  CONCLUSIONS
  The rCBF and the MABP were influenced differently by the administration of various pharmacopunctures. Further studies are needed to elucidate the underlying mechanism.
authors.affiliation: Department of Sasang Constitutional Medicine, Wonkwang University Oriental Medical Hospital, Jeonju, Korea.
authors.forename: Soo-Jung
authors.initials: SJ
authors.lastname: Park
authors.affiliation: Department of Sasang Constitutional Medicine, Wonkwang University College of Oriental Medicine, Iksan, Korea.
authors.forename: Ho-Young
authors.initials: HY
authors.lastname: Lee
authors.affiliation: Department of Sasang Constitutional Medicine, Wonkwang University College of Oriental Medicine, Iksan, Korea.
authors.forename: Tak-Hyun
authors.initials: TH
authors.lastname: Yoon
authors.affiliation: Department of Sasang Constitutional Medicine, Wonkwang University Oriental Medical Hospital, Jeonju, Korea ; Department of Sasang Constitutional Medicine, Wonkwang University College of Oriental Medicine, Iksan, Korea.
authors.forename: Jong-Cheon
authors.initials: JC
authors.lastname: Joo
keywords: Calculus Bovis-Fel Uris-Moschus; bee venom; cerebrovascular circulation; pharmacopuncture; scolopendrid