title: Think beyond the Skin: 2014 Canadian Expert Opinion Paper on Treating to Target in Plaque Psoriasis.
abstract: OBJECTIVE
  Explore the feasibility of Treat to Target in the area of psoriasis as seen in other therapeutic areas such as hypertension, hyperlipidemia, diabetes and rheumatoid arthritis.
  
  
  METHODS
  Review validated, measurable targets for psoriasis, including physician global assessment (PGA), psoriasis area and severity index (PASI) and dermatology life quality index (DLQI). Examine principles brought forth in the published European consensus on psoriasis and develop a Canadian consensus on Treat to Target in psoriasis.
  
  
  RESULTS
  As PASI and DLQI are not routinely used in the community setting, we are recommending target at a PGA of zero (clear).
  
  
  CONCLUSIONS
  Recommend that the target is a PGA of zero (clear) as it provides a simple and measurable result that the patient and physician can clearly understand.
authors.affiliation: Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC wgulliver@newlabresearch.com.
authors.forename: Wayne
authors.initials: W
authors.lastname: Gulliver
authors.affiliation: Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC.
authors.forename: Charles
authors.initials: C
authors.lastname: Lynde
authors.affiliation: Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC.
authors.forename: Jan P
authors.initials: JP
authors.lastname: Dutz
authors.affiliation: Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC.
authors.forename: Ronald B
authors.initials: RB
authors.lastname: Vender
authors.affiliation: Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC.
authors.forename: Jensen
authors.initials: J
authors.lastname: Yeung
authors.affiliation: Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC.
authors.forename: Marc
authors.initials: M
authors.lastname: Bourcier
authors.affiliation: Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC.
authors.forename: Pierre-Luc
authors.initials: PL
authors.lastname: Dion
authors.affiliation: Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC.
authors.forename: Chi-Ho
authors.initials: CH
authors.lastname: Hong
authors.affiliation: Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC.
authors.forename: Gordon
authors.initials: G
authors.lastname: Searles
authors.affiliation: Faculty of Medicine, Division of Dermatology, Memorial University, St. John's NLDepartment of Medicine, Division of Dermatology, University of Toronto, Toronto, ON and Lynderm Research Inc., Markham, ONDepartment of Dermatology and Skin Science, Child and Family Research Institute, University of British Columbia, Vancouver, BCDepartment of Medicine, McMaster University, Hamilton ON, Service of Dermatology, St. Joseph's Hospital, Hamilton, ON and Dermatrials Research, Dermatology Centre, Hamilton, ONDivision of Dermatology, Department of Medicine, University of Toronto, Toronto, ONFaculty of Medicine, Sherbrooke University, Sherbrooke, QCDepartment of Medicine, Division of Dermatology, Laval University, Quebec, QCDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, BCDepartment of Medicine, Division of Dermatology, University of Alberta, Edmonton, AB and Searles Dermatology & Aesthetics, Edmonton, ABCHUQ, Hotel-Dieu Hospital, Laval University, Quebec, QC.
authors.forename: Yves
authors.initials: Y
authors.lastname: Poulin
mesh_terms: D002170:Canada; D003880:Dermatology / Q000379:methods / Q000592:standards; D006801:Humans; D011565:Psoriasis / Q000175:diagnosis* / Q000628:therapy*; D011788:Quality of Life; D012720:Severity of Illness Index