title: Nickel-catalyzed borylation of arenes and indoles via C-H bond cleavage.
abstract: The first nickel-catalyzed method for the borylation of carbon-hydrogen bonds in arenes and indoles is described. The use of an N-heterocyclic carbene ligand is essential for an efficient reaction, with an N-cyclohexyl-substituted derivative being optimal. This method is readily applied to the gram scale synthesis of 2-borylindole.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan. tobisu@chem.eng.osakau.ac.jp chatani@chem.eng.osakau.ac.jp.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Furukawa
authors.forename: Mamoru
authors.initials: M
authors.lastname: Tobisu
authors.forename: Naoto
authors.initials: N
authors.lastname: Chatani