title: Chronic kidney disease has a significant impact on platelet inhibition of new P2Y12 inhibitors.
authors.affiliation: Département de Cardiologie, CHU Timone, Marseille F-13385, France; INSERM, UMR1062, Nutrition, Obesity and Risk of Thrombosis, F-13385 Marseille, France; Aix-Marseille Université, Faculté de Médecine, F-13385 Marseille, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Deharo
authors.affiliation: Département de Cardiologie, CHU Timone, Marseille F-13385, France; INSERM, UMR1062, Nutrition, Obesity and Risk of Thrombosis, F-13385 Marseille, France; Aix-Marseille Université, Faculté de Médecine, F-13385 Marseille, France.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Pankert
authors.affiliation: Département de Cardiologie, CHU Timone, Marseille F-13385, France; INSERM, UMR1062, Nutrition, Obesity and Risk of Thrombosis, F-13385 Marseille, France; Aix-Marseille Université, Faculté de Médecine, F-13385 Marseille, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Quilici
authors.affiliation: Département de Cardiologie, CHU Timone, Marseille F-13385, France; INSERM, UMR1062, Nutrition, Obesity and Risk of Thrombosis, F-13385 Marseille, France; Aix-Marseille Université, Faculté de Médecine, F-13385 Marseille, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Bonnet
authors.affiliation: Département de Cardiologie, CHU Timone, Marseille F-13385, France; Aix-Marseille Université, Faculté de Médecine, F-13385 Marseille, France.
authors.forename: Clemence
authors.initials: C
authors.lastname: Bassez
authors.affiliation: Assistance Publique-Hôpitaux de Marseille, Equipe Mobile d'Aide à l'Investigation (EMAI), France.
authors.forename: Valentine
authors.initials: V
authors.lastname: Verdier
authors.affiliation: INSERM, UMR1062, Nutrition, Obesity and Risk of Thrombosis, F-13385 Marseille, France; Aix-Marseille Université, Faculté de Médecine, F-13385 Marseille, France; Laboratoire d'Hématologie, CHU Timone, Marseille F-13385, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Morange
authors.affiliation: INSERM, UMR1062, Nutrition, Obesity and Risk of Thrombosis, F-13385 Marseille, France; Aix-Marseille Université, Faculté de Médecine, F-13385 Marseille, France; Laboratoire d'Hématologie, CHU Timone, Marseille F-13385, France.
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Alessi
authors.affiliation: Département de Cardiologie, CHU Timone, Marseille F-13385, France; INSERM, UMR1062, Nutrition, Obesity and Risk of Thrombosis, F-13385 Marseille, France; Aix-Marseille Université, Faculté de Médecine, F-13385 Marseille, France.
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Bonnet
authors.affiliation: Département de Cardiologie, CHU Timone, Marseille F-13385, France; INSERM, UMR1062, Nutrition, Obesity and Risk of Thrombosis, F-13385 Marseille, France; Aix-Marseille Université, Faculté de Médecine, F-13385 Marseille, France. Electronic address: thomas.cuisset@ap-hm.fr.
authors.forename: Thomas
authors.initials: T
authors.lastname: Cuisset
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood / Q000150:complications / Q000188:drug therapy; D000241:Adenosine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000494:pharmacology; D000368:Aged; D016903:Drug Monitoring / Q000379:methods; D005260:Female; D006801:Humans; D007677:Kidney Function Tests / Q000379:methods; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects*; D010979:Platelet Function Tests / Q000379:methods; D000068799:Prasugrel Hydrochloride / Q000008:administration & dosage / Q000493:pharmacokinetics; D058921:Purinergic P2Y Receptor Antagonists / Q000008:administration & dosage / Q000493:pharmacokinetics; D051436:Renal Insufficiency, Chronic / Q000097:blood / Q000150:complications / Q000503:physiopathology; D013223:Statistics as Topic; D000077486:Ticagrelor; D016896:Treatment Outcome
chemical_list: D058921:Purinergic P2Y Receptor Antagonists; D000068799:Prasugrel Hydrochloride; D000077486:Ticagrelor; D000241:Adenosine
keywords: Acute coronary syndromes; Chronic kidney disease; Keywords; P2Y12 blockers; Platelet reactivity