title: Sweet syndrome associated with interferon.
abstract: Although still very rare, drug-related cases of Sweet's syndrome have been reported. The more frequent associated medications with drug induced Sweet´s syndrome was: tetracyclines, trimethoprim-sulphamethaxazol, azatioprine, all trans retinoic acid, nitrofurantoin, granulocyte colony-stimulating factor, hydralazine, tripharil, lithium, oral contraceptives, furosemide, celecoxib and azathioprine. We only found one case of drug-induced Sweet´s syndrome secondary to pegylated interferon-alpha in combination with ribavirin reported in literature. To our knowledge, this one is the first reported case of Sweet's syndrome in association with interferon beta 1-b therapy.Also, we would like to remark the atypical localization of the lesions in our patient, with a unilateral predominance on the left lower extremity and a very severe pain.
authors.forename: Romina
authors.initials: R
authors.lastname: Rodriguez-Lojo
authors.affiliation: Hospital Universitario Lucus Augusti.
authors.forename: Iria
authors.initials: I
authors.lastname: Castiñeiras
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Juarez
authors.forename: Mercedes
authors.initials: M
authors.lastname: Lueiro
authors.forename: Ana
authors.initials: A
authors.lastname: Armesto
authors.forename: M Luisa
authors.initials: ML
authors.lastname: Fernandez-Diaz
mesh_terms: D000276:Adjuvants, Immunologic / Q000009:adverse effects*; D000328:Adult; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D000068576:Interferon beta-1b / Q000009:adverse effects*; D007866:Leg / Q000473:pathology; D009103:Multiple Sclerosis / Q000188:drug therapy*; D011239:Prednisolone / Q000627:therapeutic use; D016463:Sweet Syndrome / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000276:Adjuvants, Immunologic; D005938:Glucocorticoids; D000068576:Interferon beta-1b; D011239:Prednisolone