title: Y-chromosomal variation of local goat breeds of Turkey close to the domestication centre.
abstract: Genetic variations in chromosome Y are enabling researchers to identify paternal lineages, which are informative for introgressions and migrations. In this study, the male-specific region markers, sex-determining region-Y (SRY), amelogenin (AMELY) and zinc finger (ZFY) were analysed in seven Turkish native goat breeds, Angora, Kilis, Hair, Honamlı, Norduz, Gürcü and Abaza. A SNP in the ZFY gene defined a new haplotype Y2C. All domestic haplogroups originate from Capra aegagrus, while the finding of Y1A, Y1B, Y2A and Y2C in 32, 4, 126 and 2 Turkish domestic goats, respectively, appears to indicate a predomestic origin of the major haplotypes. The occurrence of four haplotypes in the Hair goat and, in contrast, a frequency of 96% of Y1A in the Kilis breed illustrate that Y-chromosomal variants have a more breed-dependent distribution than mitochondrial or autosomal DNA. This probably reflects male founder effects, but a role in adaptation cannot be excluded.
authors.affiliation: Department of Genetics, Faculty of Veterinary Medicine, Ankara University, Ankara, Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Cinar Kul
authors.affiliation: Department of Genetics, Faculty of Veterinary Medicine, Ankara University, Ankara, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Bilgen
authors.affiliation: Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
authors.forename: J A
authors.initials: JA
authors.lastname: Lenstra
authors.affiliation: Department of Animal Science, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University, Burdur, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Korkmaz Agaoglu
authors.affiliation: Department of Genetics, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Akyuz
authors.affiliation: Department of Genetics, Faculty of Veterinary Medicine, Ankara University, Ankara, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Ertugrul
mesh_terms: D000220:Adaptation, Biological; D000818:Animals; D000829:Animals, Domestic / Q000235:genetics*; D001947:Breeding; D004272:DNA, Mitochondrial / Q000235:genetics; D018703:Founder Effect; D005819:Genetic Markers; D014644:Genetic Variation; D006041:Goats / Q000235:genetics*; D006239:Haplotypes; D008297:Male; D008969:Molecular Sequence Data; D058974:Phylogeography; D017422:Sequence Analysis, DNA; D014421:Turkey; D014998:Y Chromosome / Q000235:genetics*
chemical_list: D004272:DNA, Mitochondrial; D005819:Genetic Markers
keywords: AMELY; SRY; Y chromosome; ZFY; goat