title: Evolving Important Role of Lutetium-177 for Therapeutic Nuclear Medicine.
abstract: Lutetium-177 ((177)Lu) is a late entrant into the nuclear medicine therapy arena but is expected to become one of the most widely used therapeutic radionuclides. This paper analyses the reason for the increasing preference of (177)Lu as a therapeutic radionuclide. While the radionuclidic properties favor its use for several therapeutic applications, the potential for large scale production of (177)Lu is also an important aspect for its acceptability as a therapeutic radionuclide. This introductory discussion also summarizes some developing clinical uses and suggested future directions for applications of (177)Lu.
authors.forename: Ambikalmajan M R
authors.initials: AM
authors.lastname: Pillai
authors.affiliation: Medical Radioisotopes Program, Oak Ridge National Laboratory (ORNL), PO Box 2008, 1 Bethel Valley Road, Oak Ridge, TN 37830-6229, Oak Ridge, TN, USA. knappffjr@ornl.gov.
authors.forename: Furn F Russ
authors.initials: FF
authors.lastname: Knapp
mesh_terms: D015195:Drug Design; D006801:Humans; D008187:Lutetium / Q000627:therapeutic use*; D009683:Nuclear Medicine / Q000379:methods*; D011868:Radioisotopes / Q000627:therapeutic use*
chemical_list: D011868:Radioisotopes; D008187:Lutetium