title: Mixed endometrial stromal and smooth muscle tumor with heart metastasis: report of a case and review of literature.
abstract: We presented a case of mixed endometrial stromal sarcoma and smooth muscle cell tumor of the uterus with intravenous metastasis into the right heart. 50 hot mutated key genes of solid tumors were detected by next generation sequencing. The literature about the diagnostic and therapeutic strategies of the disease were reviewed.
authors.affiliation: Department of Oncology, Third Xiangya Hospital, Central South University Changsha 410013, China.
authors.forename: Chenghui
authors.initials: C
authors.lastname: Huang
authors.affiliation: Department of Oncology, Third Xiangya Hospital, Central South University Changsha 410013, China.
authors.forename: Haihua
authors.initials: H
authors.lastname: Zhu
authors.affiliation: Department of Oncology, Third Xiangya Hospital, Central South University Changsha 410013, China.
authors.forename: Cong
authors.initials: C
authors.lastname: Xu
authors.affiliation: Department of Oncology, Third Xiangya Hospital, Central South University Changsha 410013, China.
authors.forename: Sophia Jennie
authors.initials: SJ
authors.lastname: Ferrance
authors.affiliation: Department of Oncology, Third Xiangya Hospital, Central South University Changsha 410013, China.
authors.forename: Peiguo
authors.initials: P
authors.lastname: Cao
authors.affiliation: Department of Oncology, Third Xiangya Hospital, Central South University Changsha 410013, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Oncology, Third Xiangya Hospital, Central South University Changsha 410013, China.
authors.forename: Jingjing
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Oncology, Third Xiangya Hospital, Central South University Changsha 410013, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Oncology, Third Xiangya Hospital, Central South University Changsha 410013, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Xia
authors.affiliation: Department of Head and Neck Surgery and Oncology Plastic Surgery, The Affiliated Cancer Hospital of Xiangya Medical School, Central South University Changsha 410006, China.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Peng
authors.affiliation: Department of Oncology, Third Xiangya Hospital, Central South University Changsha 410013, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Cao
mesh_terms: D000328:Adult; D036821:Endometrial Stromal Tumors / Q000473:pathology*; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000473:pathology; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology; D014594:Uterine Neoplasms / Q000473:pathology*
keywords: Mixed endometrial stromal and smooth muscle tumor; gene; intracardiac metastasis; next-generation sequencing; uterus