title: The direct conversion of sugars into 2,5-furandicarboxylic acid in a triphasic system.
abstract: A one-pot conversion of sugars into 2,5-furandicarboxylic acid (FDCA) is demonstrated in a triphasic system: tetraethylammonium bromide (TEAB) or water-methyl isobutyl ketone (MIBK)-water. In this reaction, sugars are first converted into 5-hydroxymethylfurfural (HMF) in TEAB or water (Phase I). The HMF in Phase I is then extracted to MIBK (Phase II) and transferred to water (Phase III), where HMF is converted into FDCA. Phase II plays multiple roles: as a bridge for HMF extraction, transportation and purification. Overall FDCA yields of 78 % and 50 % are achieved from fructose and glucose respectively.
authors.affiliation: Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669 (Singapore). ygzhang@ibn.a-star.edu.sg.
authors.forename: Guangshun
authors.initials: G
authors.lastname: Yi
authors.forename: Siew Ping
authors.initials: SP
authors.lastname: Teong
authors.forename: Yugen
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D018533:Biomass; D002241:Carbohydrates / Q000737:chemistry*; D003998:Dicarboxylic Acids / Q000737:chemistry*; D005663:Furans / Q000737:chemistry*; D008742:Methyl n-Butyl Ketone / Q000737:chemistry; D019789:Tetraethylammonium / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D002241:Carbohydrates; D003998:Dicarboxylic Acids; D005663:Furans; D014867:Water; D019789:Tetraethylammonium; D008742:Methyl n-Butyl Ketone; C551400:2,5-furandicarboxylic acid; C005458:methyl isobutyl ketone
keywords: biomass; carbohydrates; extraction; phase-transfer catalysis; renewables