title: Cryptococcus neoformans meningitis with negative cryptococcal antigen: Evaluation of a new immunochromatographic detection assay.
abstract: Detection of cryptococcal antigen in serum or cerebrospinal fluid allows cryptococcal meningitis diagnosis within few hours with >90% sensitivity. In an HIV-positive patient with Cryptococcus neoformans meningitis, initial antigen detection by immunoagglutination was negative. We thus evaluated a new immunochromatographic detection assay that exhibited a higher sensitivity.
authors.affiliation: Institute of Microbiology, Switzerland.
authors.forename: O
authors.initials: O
authors.lastname: Opota
authors.affiliation: Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
authors.forename: B
authors.initials: B
authors.lastname: Desgraz
authors.affiliation: Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Kenfak
authors.affiliation: Institute of Microbiology, Switzerland.
authors.forename: K
authors.initials: K
authors.lastname: Jaton
authors.affiliation: Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Cavassini
authors.affiliation: Institute of Microbiology, Switzerland ; Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
authors.forename: G
authors.initials: G
authors.lastname: Greub
authors.affiliation: Institute of Microbiology, Switzerland.
authors.forename: G
authors.initials: G
authors.lastname: Prod'hom
authors.affiliation: Infectious Diseases Service, University of Lausanne and University Hospital Center, Lausanne, Switzerland.
authors.forename: S
authors.initials: S
authors.lastname: Giulieri
keywords: Antigen test; Cryptococcus neoformans; HIV; immunochromatography; meningitis