title: Bioactivity of essential oil from Artemisia stolonifera (Maxim.) Komar. and its main compounds against two stored-product insects.
abstract: Artemisia stolonifera, a perennial herb, is widely distrbuted in China. The aim of this study was to analyze the essential oil from the aerial parts of Artemisia stolonifera, as well as to evaluate the bioactivity of the oil and its main constituents. The essential oil was analyzed by gas chromatography-flame ionization detector and gas chromatography-mass spectrometry that allowed characterizing 22 compounds. The main components were eucalyptol (32.93%), β-pinene (8.18%), camphor (6.12%) and terpinen-4-ol (6.11%), and obtained from the essential oil after a further isolation. During the contact toxicity tests, the essential oil (LD50 = 8.60 μg/adult) exhibited stronger toxicity against Tribolium castaneum adults than those isolated constituents, however, camphor and terpinen-4-ol showed 1 and 2 times toxicity against Lasioderma serricorne adults than the essential oil (LD50 = 12.68 μg/adult) with LD50 values of 11.30 and 5.42 μg/adult, respectively. In the fumigant toxicity tests, especially on Tribolium castaneum, the essential oil (LC50 = 1.86 mg/L air) showed almost the same level toxicity as positive control, methyl bromide (LC50 = 1.75 mg/L air). Moreover, the essential oil and its four isolated constituents also exhibited strong repellency against two stored-product insects.
authors.affiliation: Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Beijing Normal University.
authors.forename: Wen-Juan
authors.initials: WJ
authors.lastname: Zhang
authors.forename: Kai
authors.initials: K
authors.lastname: Yang
authors.forename: Chun-Xue
authors.initials: CX
authors.lastname: You
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.forename: Cheng-Fang
authors.initials: CF
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Wu
authors.forename: Zhu-Feng
authors.initials: ZF
authors.lastname: Geng
authors.forename: Yang
authors.initials: Y
authors.lastname: Su
authors.forename: Shu-Shan
authors.initials: SS
authors.lastname: Du
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Deng
mesh_terms: D000818:Animals; D001156:Artemia / Q000737:chemistry*; D000081008:Bicyclic Monoterpenes; D001643:Bridged Bicyclo Compounds / Q000302:isolation & purification / Q000633:toxicity; D002164:Camphor / Q000302:isolation & purification / Q000633:toxicity; D002849:Chromatography, Gas; D018556:Crops, Agricultural / Q000469:parasitology; D003511:Cyclohexanols / Q000302:isolation & purification / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D000077591:Eucalyptol; D005410:Flame Ionization; D061353:Food Storage; D008401:Gas Chromatography-Mass Spectrometry; D007306:Insecticides; D039821:Monoterpenes / Q000302:isolation & purification / Q000633:toxicity; D009822:Oils, Volatile / Q000032:analysis / Q000633:toxicity*; D013729:Terpenes / Q000302:isolation & purification / Q000633:toxicity; D014231:Tribolium / Q000187:drug effects*
chemical_list: D000081008:Bicyclic Monoterpenes; D001643:Bridged Bicyclo Compounds; D003511:Cyclohexanols; D007306:Insecticides; D039821:Monoterpenes; D009822:Oils, Volatile; D013729:Terpenes; C010789:beta-pinene; C034019:terpinenol-4; D002164:Camphor; D000077591:Eucalyptol