title: [Analysis of factors of intracranial infection after transnasal endoscopic crannialbase approach].
abstract: OBJECTIVE
  To analyze the factors of intracranial infection after transnasal endoscopic crannialbase approach.
  
  
  METHODS
  Retrospective analysis of 346 patients of ransnasal endoscopic crannialbase approach, logistic regression analysis of the factors was carried out.
  
  
  RESULTS
  The total number of cases of postoperative infections were 19 cases in 346 patients, the infection rate was 5.49%. The cerebrospinal fluid rhinorrhea , the restitution of skull base, the history of crannialbase approach, the history of radiotherapy and diabetes were infection fators after transnasal endoscopic diabetes (P < 0.05), while sex,age,operative approach,the use of artificial material,longer application of antibiotics before or after operation,and the history of chemotherapy had no obvious effects (P > 0.05).
  
  
  CONCLUSIONS
  Intracranial infection after transnasal endoscopic the use of artificial material was affected by many factors. Much attention should be paid for the intracranial infection prevention.
authors.forename: Huanxin
authors.initials: H
authors.lastname: Yu
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
mesh_terms: D002559:Cerebrospinal Fluid Rhinorrhea / Q000209:etiology*; D004724:Endoscopy; D006801:Humans; D011183:Postoperative Complications; D012189:Retrospective Studies; D019291:Skull Base / Q000601:surgery*