title: Guidance on patient consultation. Current evidence for prostate-specific antigen screening in healthy men and treatment options for men with proven localised prostate cancer.
abstract: The main objective of this review is to summarise, for primary and secondary care doctors, the management options and current supporting evidence for clinically localised prostate cancer. We review all aspects of management including current guidelines on early cancer detection and the importance of informed consent on PSA-based screening and assess the most common treatment options and the evidence for managing patients with low-, medium-, and high-risk disease.
authors.affiliation: Karolinska Institute, Department of Molecular Medicine and Surgery, Section of Urology, Solna, Stockholm, Sweden, gpini3@gmail.com.
authors.forename: Giovannalberto
authors.initials: G
authors.lastname: Pini
authors.forename: Justin
authors.initials: J
authors.lastname: Collins
authors.forename: Pirus
authors.initials: P
authors.lastname: Ghadjar
authors.forename: Peter
authors.initials: P
authors.lastname: Wiklund
mesh_terms: D055088:Early Detection of Cancer / Q000592:standards*; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008403:Mass Screening; D017410:Practice Guidelines as Topic; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000175:diagnosis / Q000628:therapy; D012017:Referral and Consultation / Q000592:standards*
chemical_list: D017430:Prostate-Specific Antigen