title: Comparison of automated breast ultrasonography to handheld ultrasonography in detecting and diagnosing breast lesions.
abstract: BACKGROUND
  Automated breast ultrasonography (ABUS) is increasingly used as a screening tool. Several studies have demonstrated a similar diagnostic performance for ABUS compared with handheld ultrasonography (HHUS), but the overall results have been controversial.
  
  
  OBJECTIVE
  To compare the clinical utility of ABUS and HHUS for detection and diagnosis of breast lesions.
  
  
  METHODS
  ABUS and HHUS images of suspicious breast lesions were obtained for 173 consecutive women scheduled to undergo ultrasonography (US)-guided or stereotactic biopsy. There were a total of 206 lesions, 46 of which were malignant and 160 benign. Three breast radiologists took part in this study: two reviewed the ABUS images, and the third reviewed all of the images, ABUS and HHUS, as well as the patients' medical records. The biopsied-lesion-detection rates were obtained. Using the Breast Imaging Reporting and Data System (BI-RADS), the images of the biopsied lesions were evaluated. Factors affecting ABUS detectability were analyzed.
  
  
  RESULTS
  The overall detection rates were 83.0% for ABUS and 94.2% for HHUS. Ten lesions were not detected on either HHUS or ABUS and these were microcalcifications (one malignancy and nine benign lesions). Of the 194 HHUS-detected lesions, 169 were detected by ABUS and 25 benign were not. ABUS less frequently detected lesions of smaller size as well as those of benign appearance and lower final-assessment category (P = 0.011 and P < 0.0001, respectively).
  
  
  CONCLUSIONS
  ABUS detected all of the malignant lesions that were detected on HHUS. ABUS missed several smaller benign lesions.
authors.affiliation: Department of Radiology, Hallym University Medical Center, The Hallym University of Korea, Chuncheon, Republic of Korea.
authors.forename: Su Kyung
authors.initials: SK
authors.lastname: Jeh
authors.affiliation: Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea rad-ksh@catholic.ac.kr.
authors.forename: Sung Hun
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Radiology, Hallym University Medical Center, The Hallym University of Korea, Chuncheon, Republic of Korea.
authors.forename: Jae Jeong
authors.initials: JJ
authors.lastname: Choi
authors.affiliation: Department of General Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
authors.forename: Sang Sul
authors.initials: SS
authors.lastname: Jung
authors.affiliation: Department of General Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
authors.forename: Byung Joo
authors.initials: BJ
authors.lastname: Choe
authors.affiliation: Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
authors.forename: Sarah
authors.initials: S
authors.lastname: Park
authors.affiliation: Department of Biostatistics, Clinical Research Coordinating Center, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
authors.forename: Mi Sun
authors.initials: MS
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008875:Middle Aged; D015588:Observer Variation; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016217:Ultrasonography, Mammary / Q000379:methods*; D055815:Young Adult
keywords: Ultrasonography; breast; diagnosis; early detection of cancer; mammary