title: Transcatheter mitral valve repair therapies for primary and secondary mitral regurgitation.
abstract: Mitral regurgitation is one of the most prevalent valvular heart diseases and its prevalence is related to population aging. Elderly patients with age-associated co-morbidities have an increased risk for conventional mitral valve surgery. Transcatheter mitral valve repair has emerged as a feasible and safe alternative in patients with contraindications for surgery or high operative risk. Several transcatheter mitral repair technologies have been developed during the last decade. While the development of some devices was abandoned due to suboptimal results, others demonstrated to be safe and effective and have been included in current practice guidelines. Not all technologies are suitable for all mitral anatomies and regurgitation mechanisms. Therefore, accurate evaluation of mitral valve anatomy and function are pivotal to the success of these therapies. Cardiac imaging plays a central role in selecting patients, guiding the procedure and evaluating the durability of the repair at follow-up.
authors.affiliation: Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Ibtihal
authors.initials: I
authors.lastname: Al Amri
authors.forename: Frank
authors.initials: F
authors.lastname: van der Kley
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Schalij
authors.forename: Nina
authors.initials: N
authors.lastname: Ajmone Marsan
authors.forename: Victoria
authors.initials: V
authors.lastname: Delgado
mesh_terms: D006328:Cardiac Catheterization; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D058386:Mitral Valve Annuloplasty / Q000379:methods*; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D025321:Surgery, Computer-Assisted
keywords: mitral regurgitation; mitral repair; mitral valve; multimodality imaging; percutaneous valve repair