title: [Effect of low-intensity 900 MHz frequency electromagnetic radiation on rat liver and blood serum enzyme activities].
abstract: The comparative analysis of the rat liver and blood serum creatine kinase, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase and purine nucleoside phosphorylase post-radiation activity levels after a total two-hour long single and fractional exposure of the animals to low-intensity 900 MHz frequency electromagnetic field showed that the most sensitive enzymes to the both schedules of radiation are the liver creatine kinase, as well as the blood serum creatine kinase and alkaline phosphatase. According to the comparative analysis of the dynamics of changes in the activity level of the liver and blood serum creatine kinase, alanine aminotransferase, aspartate aminotransferase and purine nucleoside phosphorylase, both single and fractional radiation schedules do not affect the permeability of a hepatocyte cell membrane, but rather cause changes in their energetic metabolism. The correlation analysis of the post-radiation activity level changes of the investigated enzymes did not reveal a clear relationship between them. The dynamics of post-radiation changes in the activity of investigated enzyme levels following a single and short-term fractional schedules of radiation did not differ essentially.
authors.forename: L S
authors.initials: LS
authors.lastname: Nersesova
authors.forename: M S
authors.initials: MS
authors.lastname: Petrosian
authors.forename: M G
authors.initials: MG
authors.lastname: Gazariants
authors.forename: Z S
authors.initials: ZS
authors.lastname: Mkrtchian
authors.forename: G O
authors.initials: GO
authors.lastname: Meliksetian
authors.forename: L G
authors.initials: LG
authors.lastname: Pogosian
authors.forename: Zh I
authors.initials: ZhI
authors.lastname: Akopian
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D040421:Cell Phone; D003402:Creatine Kinase / Q000097:blood; D060733:Electromagnetic Radiation; D022781:Hepatocytes / Q000201:enzymology* / Q000528:radiation effects; D008099:Liver / Q000201:enzymology* / Q000528:radiation effects; D011683:Purine-Nucleoside Phosphorylase / Q000097:blood; D051381:Rats
chemical_list: D011683:Purine-Nucleoside Phosphorylase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D003402:Creatine Kinase; D000469:Alkaline Phosphatase