title: Methadone for Fun Sake… Kidneys Are at Stake!!!
abstract: Acute renal failure from rhabdomyolysis is a well-established clinical entity; however, rhabdomyolysis exclusively caused by the ingestion of methadone requiring hemodialysis is very uncommon. With a similar mechanism to opiates, methadone can cause rhabdomyolysis and further consequences. Given the increasing use of methadone as a therapy for opiate dependence, clinicians prescribing this medication should be aware of this life-threatening complication.
authors.affiliation: 1Department of Cardiology, Newark Beth Israel Medical Center, Newark, NJ; and 2Department of Internal Medicine, Metropolitan Hospital Center, New York, NY.
authors.forename: Sameer
authors.initials: S
authors.lastname: Chaudhari
authors.forename: Kashmira
authors.initials: K
authors.lastname: Wankhedkar
authors.forename: Beata
authors.initials: B
authors.lastname: Popis-Matejak
authors.forename: Donald
authors.initials: D
authors.lastname: Baumstein
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male; D008691:Methadone / Q000009:adverse effects*; D008875:Middle Aged; D058850:Opiate Substitution Treatment / Q000009:adverse effects*; D009293:Opioid-Related Disorders / Q000188:drug therapy; D006435:Renal Dialysis; D012206:Rhabdomyolysis / Q000139:chemically induced* / Q000150:complications*
chemical_list: D008691:Methadone