title: [Mortality from meningococcal disease in the city of São Paulo, Brazil: characteristics and predictors].
abstract: This study aimed to describe the magnitude, mortality, and case-fatality rate from meningococcal disease and to investigate predictors of death from this cause in the city of São Paulo, Brazil, from 1986 to 2004, using unconditional multiple logistic regression. We analyzed 10,087 cases of meningococcal disease in the city. Mean annual mortality was 1.0/100,000 inhabitants, ranging from 0.2 to 1.8. Case-fatality was 20.5%, with major differences according to age, serogroup, and type of hospital. Predictors of death from meningococcal disease were age, especially the age brackets from one to two years and 40 years and older, and serogroup W. The results can contribute to the elaboration of public policies with a focus on the organization of hospital care and protocols to promote greater treatment effectiveness and application of vaccination strategies that decrease the incidence in groups at greatest risk of death from meningococcal disease.
authors.forename: Eliana Tiemi
authors.initials: ET
authors.lastname: Masuda
authors.forename: Telma Regina Marques Pinto
authors.initials: TR
authors.lastname: Carvalhanas
authors.forename: Rachel Maria Borelli Paradella
authors.initials: RM
authors.lastname: Fernandes
authors.forename: Silvana Tadeu
authors.initials: ST
authors.lastname: Casagrande
authors.forename: Paula Suzuki
authors.initials: PS
authors.lastname: Okada
authors.forename: Eliseu Alves
authors.initials: EA
authors.lastname: Waldman
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D016015:Logistic Models; D008297:Male; D008589:Meningococcal Infections / Q000401:mortality*; D012307:Risk Factors; D014505:Urban Population; D055815:Young Adult