title: [Insulin resistance pathogenesis in metabolic obesity].
abstract: In this review we discuss the molecular mechanisms of insulin resistance concomitant with metabolic inflammation. We also analyze the world results of experimental and clinical studies which aimed at identifying the molecular targets for the development of new prevention and treatment of insulin resistance.
authors.forename: L S
authors.initials: LS
authors.lastname: Litvinova
authors.forename: E V
authors.initials: EV
authors.lastname: Kirienkova
authors.forename: I O
authors.initials: IO
authors.lastname: Mazunin
authors.forename: M A
authors.initials: MA
authors.lastname: Vasilenko
authors.forename: N S
authors.initials: NS
authors.lastname: Fattakhov
mesh_terms: D000818:Animals; D044882:Glucose Metabolism Disorders / Q000209:etiology / Q000378:metabolism*; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D007328:Insulin / Q000378:metabolism*; D007333:Insulin Resistance; D009765:Obesity / Q000209:etiology / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D007328:Insulin
keywords: insulin resistance; metabolic syndrome; obesity; type 2 diabetes