title: Clinical spectrum of Treacher Collins syndrome.
abstract: Treacher Collins syndrome (TCS) is the most common of the human mandibulofacial dysostosis disorders. It is an autosomal-dominant disorder of the craniofacial development occurring between the fifth and the eighth weeks of embryonic development with an incidence of 1/50,000 live births, range between 1-40,000 and 1-70,000. We present here the various clinical, radiographical and other diagnostic findings of the TCS to correlate the clinical assessment with the diagnostic imaging and review the various investigations and management options being carried out to improve their facial deformity.
authors.affiliation: Professor, Department of Anatomy, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
authors.forename: Divya
authors.initials: D
authors.lastname: Mehrotra
authors.affiliation: Professor Emeritus, Department of Anatomy, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
authors.forename: Mahdi
authors.initials: M
authors.lastname: Hasan
authors.affiliation: Research Associate, Department of Oral and Maxillofacial Surgery, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Pandey
authors.affiliation: Research Associate, Department of Oral and Maxillofacial Surgery, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
authors.forename: Sumit
authors.initials: S
authors.lastname: Kumar
keywords: Bite force; TCOF1; Treacher Collins syndrome; missing zygomatic arch