title: Early planning activity in frontal and parietal cortex in a simplified task.
abstract: Cortical planning activity has traditionally been probed with visual targets. However, external sensory signals might obscure early correlates of internally generated plans. We devised a nonspatial decision-making task in which the monkey is encouraged to decide randomly whether to reach or saccade in the absence of sensory stimuli. Neurons in frontal and parietal planning areas (in and around the arcuate and intraparietal sulci) showed responses predictive of the monkey's upcoming movement at early stages during the planning process. Neurons predicted the animal's future movements several seconds beforehand, sometimes before the trial even began. These data cast new light on the role of the cerebral cortex in the action planning process, when the animal is free to decide on his own actions in the absence of extraneous sensory cues.
authors.affiliation: Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California; and Program in Computation and Neural Systems, California Institute of Technology, Pasadena, California chess@alumni.caltech.edu.
authors.forename: Chess
authors.initials: C
authors.lastname: Stetson
authors.affiliation: Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California; and Program in Computation and Neural Systems, California Institute of Technology, Pasadena, California.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Andersen
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D003463:Cues; D003657:Decision Making / Q000502:physiology*; D005625:Frontal Lobe / Q000166:cytology / Q000502:physiology*; D033182:Intention; D008253:Macaca mulatta; D008297:Male; D009068:Movement / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D010296:Parietal Lobe / Q000166:cytology / Q000502:physiology*; D010775:Photic Stimulation; D012438:Saccades
keywords: decisions; motor; parietal; planning; target