title: Harvesting canthinones: identification of the optimal seasonal point of harvest of Zanthoxylum chiloperone leaves as a source of 5-methoxycanthin-6-one.
abstract: This article is focused on the seasonal variation in the contents of 5-methoxycanthin-6-one from the leaves of Zanthoxylum chiloperone (Rutaceae). Based on the pharmacological interest presented by 5-methoxycanthin-6-one, its seasonal variation in Z. chiloperone leaves was analysed in order to determine the best time for harvesting, optimising the 5-methoxycanthin-6-one content. The seasonal dynamics of canthinone alkaloids can be the key to improve the isolation from natural sustainable sources, such as leaves. Complementarily, this study describes the phytochemistry of leaf from this Ruraceae species.
authors.affiliation: a Laboratoire de Pharmacognosie associé au CNRS, UMR 8076 BioCIS, LabEx LERMIT, Faculté de Pharmacie, Université Paris-Sud , 5, Rue J.-B. Clément, 92296 Châtenay-Malabry , France.
authors.forename: Gerardo
authors.initials: G
authors.lastname: Cebrián-Torrejón
authors.forename: Landry
authors.initials: L
authors.lastname: Kablan
authors.forename: Maria Elena
authors.initials: ME
authors.lastname: Ferreira
authors.forename: David
authors.initials: D
authors.lastname: Rodríguez de la Cruz
authors.forename: Antonio
authors.initials: A
authors.lastname: Doménech-Carbó
authors.forename: Ninfa
authors.initials: N
authors.lastname: Vera de Bilbao
authors.forename: Antonieta
authors.initials: A
authors.lastname: Rojas de Arias
authors.forename: Bruno
authors.initials: B
authors.lastname: Figadère
authors.forename: Erwan
authors.initials: E
authors.lastname: Poupon
authors.forename: Alain
authors.initials: A
authors.lastname: Fournet
mesh_terms: D002243:Carbolines / Q000302:isolation & purification*; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry*; D012621:Seasons; D013696:Temperature; D032106:Zanthoxylum / Q000737:chemistry*
chemical_list: D002243:Carbolines; C468517:5-methoxycanthin-6-one
keywords: HPLC–UV–MS; MS–MS; Rutaceae; Zanthoxylum chiloperone; alkaloids; alkylamide; benzylisoquinoline; canthinone; electrochemistry; phytochemistry; seasonality; sustainability