title: Rotors in patients with persistent atrial fibrillation: case report of a left atrial appendage rotor identified by a novel computational mapping algorithm integrated into 3-dimensional mapping and termination of atrial fibrillation with ablation.
abstract: Recent clinical trials using panoramic mapping techniques have shown success in targeting rotors and focal impulses in atrial fibrillation (AF). Ablations directed toward these organized sources improve outcomes in AF. The left atrial appendage (LAA) has been suspected as a possible extrapulmonary source of AF, and ablation within the LAA or electrical isolation of the LAA improves outcomes in certain cases. This case highlights a unique example of panoramic imaging created with a computational mapping algorithm integrated in 3-dimensional mapping, which identified rotors within the LAA. Furthermore, ablations performed near an identified rotor core within the LAA terminated AF.
authors.affiliation: Division of Cardiac Electrophysiology, Mercy Heart & Vascular Center, St Louis, 625 South New Ballas Road, Suite 2030, St Louis, MO 63141, USA. Electronic address: tkurian76@gmail.com.
authors.forename: Thomas
authors.initials: T
authors.lastname: Kurian
authors.affiliation: Division of Cardiac Electrophysiology, Mercy Heart & Vascular Center, St Louis, 625 South New Ballas Road, Suite 2030, St Louis, MO 63141, USA.
authors.forename: Amit
authors.initials: A
authors.lastname: Doshi
authors.affiliation: CardioNXT, Inc, 10955 Westmoor Drive, Westminster, CO 80021, USA.
authors.forename: Paul
authors.initials: P
authors.lastname: Kessman
authors.affiliation: CardioNXT, Inc, 10955 Westmoor Drive, Westminster, CO 80021, USA.
authors.forename: Bao
authors.initials: B
authors.lastname: Nguyen
authors.affiliation: CardioNXT, Inc, 10955 Westmoor Drive, Westminster, CO 80021, USA.
authors.forename: Jerome
authors.initials: J
authors.lastname: Edwards
authors.affiliation: Division of Cardiac Electrophysiology, Mercy Heart & Vascular Center, St Louis, 625 South New Ballas Road, Suite 2030, St Louis, MO 63141, USA.
authors.forename: Stephen
authors.initials: S
authors.lastname: Pieper
authors.affiliation: Department of Biomedical Engineering, Washington University in St Louis, 360 Whitaker Hall, 1 Brookings Drive, St Louis, MO 63130, USA.
authors.forename: Igor
authors.initials: I
authors.lastname: Efimov
authors.affiliation: CardioNXT, Inc, 10955 Westmoor Drive, Westminster, CO 80021, USA.
authors.forename: Ajit H
authors.initials: AH
authors.lastname: Janardhan
authors.affiliation: Division of Cardiac Electrophysiology, Mercy Heart & Vascular Center, St Louis, 625 South New Ballas Road, Suite 2030, St Louis, MO 63141, USA.
authors.forename: Mauricio
authors.initials: M
authors.lastname: Sanchez
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D017115:Catheter Ablation; D004562:Electrocardiography / Q000379:methods*; D022062:Electrophysiologic Techniques, Cardiac / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male
keywords: Ablation; Left atrial appendage; Panoramic AF mapping; Persistent atrial fibrillation