title: Modeling an irritant gas plume for epidemiologic study.
abstract: Plume dispersion modeling systems are often used in assessing human exposures to chemical hazards for epidemiologic study. We modeled the 2005 Graniteville, South Carolina, 54,915 kg railcar chlorine release using both the Areal Locations of Hazardous Atmospheres and Hazard Prediction and Assessment Capability (HPAC) plume modeling systems. We estimated the release rate by an engineering analysis combining semi-quantitative observations and fundamental physical principles. The use of regional meteorological conditions was validated by comparing concentration estimates generated by two source-location weather data-sets. The HPAC model estimated a chlorine plume with 20 ppm outdoor concentrations up to 7 km downwind and 0.25 km upwind/downgrade. A comparative analysis of our two models showed that HPAC was the best candidate for use as a model system on which epidemiologic studies could be based after further model validation. Further validation studies are needed before individual exposure estimates can be reliable and the chlorine plume more definitively modeled.
authors.affiliation: a Department of Global Environmental Health Sciences , Tulane University School of Public Health and Tropical Medicine , New Orleans , LA , USA.
authors.forename: Dev D
authors.initials: DD
authors.lastname: Jani
authors.affiliation: b Department of Epidemiology and Biostatistics , University of South Carolina Arnold School of Public Health , Columbia , SC , USA.
authors.forename: David
authors.initials: D
authors.lastname: Reed
authors.affiliation: c Department of Environmental Health Sciences , University of South Carolina Arnold School of Public Health , Columbia , SC , USA.
authors.forename: Charles E
authors.initials: CE
authors.lastname: Feigley
authors.affiliation: a Department of Global Environmental Health Sciences , Tulane University School of Public Health and Tropical Medicine , New Orleans , LA , USA.
authors.forename: Erik R
authors.initials: ER
authors.lastname: Svendsen
mesh_terms: D000393:Air Pollutants / Q000032:analysis; D002713:Chlorine / Q000032:analysis*; D004784:Environmental Monitoring / Q000379:methods*; D005740:Gases / Q000032:analysis; D015386:Hazardous Substances / Q000032:analysis*; D008962:Models, Theoretical
chemical_list: D000393:Air Pollutants; D005740:Gases; D015386:Hazardous Substances; D002713:Chlorine
keywords: agriculture; atmospheric; epidemiology; risk