title: New PFO device for closure of patent foramen ovale in patients who had a history of cryptogenic stroke; a report of 14 cases.
abstract: OBJECTIVE
  The Cocoon PFO Occluder is a device for percutaneous closure of inter-atrial communications. Its self-centering characteristics make it attractive for closure of patent foramen ovales (PFOs) with or without atrial septal aneurysms. The goal of this study is to report the immediate and follow-up results of the first 14 patients in implanted with the Cocoon PFO Occluder.
  
  
  METHODS
  This is a retrospective report of immediate and short-term clinical and echocardiographic outcome of patients who underwent transcatheter closure of PFO because of paradoxical embolism. Procedural success was defined as successful deployment of the device and effective occlusion (no, or trivial, shunt after device placement). All patients had a transesophageal echocardiography (TEE) with saline contrast injection at baseline and clinical follow-up at 6 months.
  
  
  RESULTS
  Between September 2012 and March 2014, 14 patients had successfully undergone transcatheter closure of PFO using Cocoon device. During follow-up none of the patients had a recurrence of stroke after device closure. No residual shunt was observed in any patients at follow-up.
  
  
  CONCLUSIONS
  Transcatheter closure of PFO with the Cocoon PFO device is safe and effective and can be used for preventing recurrent strokes in patients who present with cryptogenic stroke and PFO.
authors.forename: Suphot
authors.initials: S
authors.lastname: Srimahachota
authors.forename: Nakarin
authors.initials: N
authors.lastname: Sansanayudh
authors.forename: Vorarit
authors.initials: V
authors.lastname: Lertsuwunseri
authors.forename: Jiranut
authors.initials: J
authors.lastname: Cholteesupachai
authors.forename: Pornthep
authors.initials: P
authors.lastname: Lertsapcharoen
mesh_terms: D000328:Adult; D000368:Aged; D017548:Echocardiography, Transesophageal; D005260:Female; D054092:Foramen Ovale, Patent / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants; D012189:Retrospective Studies; D020521:Stroke / Q000503:physiopathology*