title: Microwave-assisted Extraction of Alantolactone and Isoalantolactone from Inula helenium.
abstract: Microwave-assisted extraction was used for the extraction of alantolactone and isoalantolactone from Inula helenium. Effects of various experimental factors including ethanol concentration, particle size, microwave radiation time, the ratio of material to liquid and extraction temperature on yield of alantolactone and isoalantolactone were evaluated. The optimal extracting process of the alantolactone and isoalantolactone from the root of the Inula helenium was 1 g plant sample (sifted through 140 mesh) mixed with 15 ml of 80% ethanol solution, microwave radiation 120 s at 50°. Under these optimal conditions, the yield of alantolactone and isoalantolactone was 31.83±2.08 mg/g and 21.25±1.37 mg/g, respectively. Compared with heat reflux extraction, ultrasound-assisted extraction, microwave-assisted extraction was more efficient and timesaving for the extraction of alantolactone and isoalantolactone from Inula helenium.
authors.affiliation: Department of Pharmacy, Hebei North University, No.11 Zuanshi South Road, Zhangjiakou-075 000, China.
authors.forename: Y M
authors.initials: YM
authors.lastname: Zhao
authors.affiliation: Department of Pharmacy, Hebei North University, No.11 Zuanshi South Road, Zhangjiakou-075 000, China.
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Pharmacy, Hebei North University, No.11 Zuanshi South Road, Zhangjiakou-075 000, China.
authors.forename: H B
authors.initials: HB
authors.lastname: Liu
authors.affiliation: Department of Pharmacy, Hebei North University, No.11 Zuanshi South Road, Zhangjiakou-075 000, China.
authors.forename: C Y
authors.initials: CY
authors.lastname: Guo
authors.affiliation: Department of Pharmacy, Hebei North University, No.11 Zuanshi South Road, Zhangjiakou-075 000, China.
authors.forename: W M
authors.initials: WM
authors.lastname: Zhang
keywords: Inula helenium; alantolactone; isoalantolactone; microwave-assisted extraction