title: Coriander (Coriandrum sativum L.) and its bioactive constituents.
abstract: Coriander (Coriandrum sativum L.), a member of the Apiaceae family, is among most widely used medicinal plant, possessing nutritional as well as medicinal properties. Thus, the aim of this updated review is to highlight the importance of coriander as a potential source of bioactive constituents and to summarize their biological activities as well as their different applications from data obtained in recent literature, with critical analysis on the gaps and potential for future investigations. A literature review was carried out by searching on the electronic databases including PubMed, Scopus, ScienceDirect, and Google Scholar for studies focusing on the biological and pharmacological activities of coriander seed and herb bioactive constituents. All recent English-language articles published between 2000 and 2014 were searched using the terms 'C. sativum', 'medicinal plant', 'bioactive constituents', and 'biological activities'. Subsequently, coriander seed and herb essential oils have been actively investigated for their chemical composition and biological activities including antimicrobial, antioxidant, hypoglycemic, hypolipidemic, anxiolytic, analgesic, anti-inflammatory, anti-convulsant and anti-cancer activities, among others. Although coriander has been reported to possess a wide range of traditional medicinal uses, no report is available in its effectiveness use in reactive airway diseases such as asthma and bronchiolitis. In brief, the information presented herein will be helpful to create more interest towards this medicinal species by defining novel pharmacological and clinical applications and hence, may be useful in developing new drug formulations in the future or by employing coriander bioactive constituents in combination with conventional drugs to enhance the treatment of diseases such as Alzheimer and cancer.
authors.affiliation: National Agronomic Institute of Tunisia, 43, Av. Charles Nicolle, 1082 Tunis, Tunisia; Higher Agronomic Institute of Chott-Mariem, BP 47, 4042 Chott Meriem, Sousse, Tunisia. Electronic address: bochra_laribi@yahoo.fr.
authors.forename: Bochra
authors.initials: B
authors.lastname: Laribi
authors.affiliation: National Agronomic Institute of Tunisia, 43, Av. Charles Nicolle, 1082 Tunis, Tunisia.
authors.forename: Karima
authors.initials: K
authors.lastname: Kouki
authors.affiliation: National Agronomic Institute of Tunisia, 43, Av. Charles Nicolle, 1082 Tunis, Tunisia; Higher Agronomic Institute of Chott-Mariem, BP 47, 4042 Chott Meriem, Sousse, Tunisia.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: M'Hamdi
authors.affiliation: National Agronomic Institute of Tunisia, 43, Av. Charles Nicolle, 1082 Tunis, Tunisia.
authors.forename: Taoufik
authors.initials: T
authors.lastname: Bettaieb
mesh_terms: D028526:Coriandrum / Q000737:chemistry*; D020834:Ethnopharmacology; D064209:Phytochemicals / Q000032:analysis*; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D064209:Phytochemicals
keywords: (+)-Linalool (S)-(+)-linalool (PubChem CID:6549); (E)-2-decenal (PubChem CID:2583345); (E)-2-dodecen-1-ol (PubChem CID:90733); (E)-2-undecen-1-ol (PubChem CID:61968); 2-Decen-1-ol (PubChem CID:5364942); Anethole (PubChem CID:637563); Bioactive constituents; Biological activities; Camphor (PubChem CID:2537); Citronellal (PubChem CID:7794); Coriandrum sativum L; Dec-9-en-1-ol (PubChem CID:25612); Decanal (PubChem CID:8175); Decanol (PubChem CID:8174); Geraniol (PubChem CID:637566); Geranyl acetate (PubChem CID:1549026); Herb; Limonene (PubChem CID:22311); Linalyl-acetate (PubChem CID:8294); Neryl acetate (PubChem CID:7780); Nonane (PubChem CID:8141); Seed; Tetradecenol (PubChem CID:120110); Tridecanal (PubChem CID:31291); Tridecanol (PubChem CID:25311); Undecanal (PubChem CID:8186); Undecanol (PubChem CID:8184); cis-Dihydrocarvone (PubChem CID:443167); n-Tetradecanol (PubChem CID:8209); p-Cymene (PubChem CID:7463); α-Cedrene (PubChem CID:6431015); α-Farnasene (PubChem CID:5281516); α-Phellandrene (PubChem CID:7460); α-Pinene (PubChem CID:6654); β-Pinene (PubChem CID:14896); γ-Terpinene (PubChem CID:7461)