title: Cryosurgery in association with itraconazole for the treatment of feline sporotrichosis.
abstract: OBJECTIVE
  We evaluated the efficacy of cryosurgery in association with itraconazole for the treatment of feline sporotrichosis. We also compared the length of treatment protocol with others reported in the literature.
  
  
  METHODS
  Cats naturally infected with fungi of the Sporothrix schenckii complex were evaluated. Diagnosis was confirmed by cytology and fungal culture. Prior to the cryosurgical procedure, every animal was receiving itraconazole 10 mg/kg/day PO, for different time periods. The same protocol was maintained until 4 weeks after complete healing of the lesions.
  
  
  RESULTS
  Eleven of 13 cats were considered clinically cured. The treatment duration ranged from 14-64 weeks (median 32 weeks).
  
  
  CONCLUSIONS
  The combination of cryosurgery and itraconazole was effective in treating cases of feline sporotrichosis and decreased the treatment length compared with protocols using only medication.
authors.affiliation: University of Minnesota, Saint Paul, MN, USA clarissaps@globo.com.
authors.forename: Clarissa Pimentel
authors.initials: CP
authors.lastname: de Souza
authors.affiliation: Universidade Anhembi Morumbi, Sao Paulo, Brazil.
authors.forename: Ronaldo
authors.initials: R
authors.lastname: Lucas
authors.affiliation: Universidade Federal Rural do Rio de Janeiro, Seropedica, Brazil.
authors.forename: Regina H R
authors.initials: RH
authors.lastname: Ramadinha
authors.affiliation: Universidade Anhembi Morumbi, Sao Paulo, Brazil.
authors.forename: Tifanny B C P
authors.initials: TB
authors.lastname: Pires
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use; D002371:Cat Diseases / Q000188:drug therapy* / Q000601:surgery*; D002415:Cats; D003452:Cryosurgery / Q000379:methods / Q000662:veterinary*; D004359:Drug Therapy, Combination / Q000662:veterinary; D017964:Itraconazole / Q000627:therapeutic use; D013174:Sporotrichosis / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole