title: Differentiation of enantiomers by 2D NMR spectroscopy at 1 T using residual dipolar couplings.
abstract: Differentiating enantiomers using 2D bench-top NMR spectroscopy. Spectrometers working with permanent magnets at 1 T field strength allow the acquisition of 2D data sets. In conjunction with previously reported chiral alignment media, this setup allows the measurement of enantiomeric excess via residual dipolar couplings in stretched gelatine as a result of the reduced line width obtained by 2D J-resolved spectroscopy.
authors.affiliation: Institut für Organische Chemie (IOC) and Institut für Biologische Grenzflächen (IBG), Karlsruher Institut für Technologie (KIT), Fritz-Haber-Weg 6, 76131, Karlsruhe, Germany.
authors.forename: Martin R M
authors.initials: MR
authors.lastname: Koos
authors.affiliation: Institut für Technische und Makromolekulare Chemie (ITMC), Lehrstuhl für Makromolekulare Chemie, RWTH Aachen, Worringerweg 1, 52074, Aachen, Germany.
authors.forename: Ernesto
authors.initials: E
authors.lastname: Danieli
authors.affiliation: Magritek GmbH, Pauwelsstrasse 8, 52068, Aachen, Germany.
authors.forename: Federico
authors.initials: F
authors.lastname: Casanova
authors.affiliation: Institut für Technische und Makromolekulare Chemie (ITMC), Lehrstuhl für Makromolekulare Chemie, RWTH Aachen, Worringerweg 1, 52074, Aachen, Germany.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Blümich
authors.affiliation: Institut für Organische Chemie (IOC) and Institut für Biologische Grenzflächen (IBG), Karlsruher Institut für Technologie (KIT), Fritz-Haber-Weg 6, 76131, Karlsruhe, Germany.
authors.forename: Burkhard
authors.initials: B
authors.lastname: Luy
keywords: RDC; chiral alignment media; differentiation of enantiomers; enantiomeric excess; low-field NMR