title: Direct fluorination of styrenes.
abstract: We have developed a practical method to synthesize fluorostyrene compounds. A mild and regioselective mono-fluorination reaction occurred smoothly for various di- and trisubstituted styrenes in the presence of RuCl3 and N-fluorobenzenesulfonimide (NFSI). A tandem alkyne hydroarylation-olefin fluorination reaction was also developed using an Au catalyst.
authors.affiliation: Key Laboratory of Chemical Genomics, Peking University, Shenzhen Graduate School, Shenzhen, 518055 China. huangyong@pkusz.edu.cn.
authors.forename: Qian
authors.initials: Q
authors.lastname: Shao
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
mesh_terms: D002384:Catalysis; D054879:Halogenation; D017975:Ruthenium Compounds / Q000737:chemistry; D013343:Styrenes / Q000737:chemistry*; D013449:Sulfonamides / Q000737:chemistry; D000096926:Benzenesulfonamides
chemical_list: D017975:Ruthenium Compounds; D013343:Styrenes; D013449:Sulfonamides; C523711:N-fluorobenzenesulfonimide; D000096926:Benzenesulfonamides; C038365:ruthenium chloride