title: Xanthogranulomatous gastritis associated with actinomycosis: report of a case presenting as a large submucosal mass.
abstract: Xanthogranulomatous gastritis (XGG) is a rarely encountered condition, and its causative mechanism is still unclear. Given that some types of xanthogranulomatous inflammation (XGI) are associated with pathogens, infection should be considered as a possible cause of XGG. Herein, we report a case of an 86-year-old woman presenting with a large, bleeding lesion resembling a submucosal tumor. Distal gastrectomy was performed, and the surgically resected specimen revealed a mass measuring 6 × 4.5 × 3 cm and appearing yellowish on the cut surface. Histopathological examination revealed a few Actinomyces "sulfur granules" and cellular composition characteristic of XGI, supporting a diagnosis of XGG associated with actinomycosis. Gastric actinomycosis is a rare condition and has not previously been reported in association with XGG, although rare cases of XGI associated with actinomycosis have been documented in other organs.
authors.affiliation: Department of Pathology, Shizuoka Saiseikai General Hospital Shizuoka, Japan ; Department of Pathology, Fujieda Municipal General Hospital Shizuoka, Japan.
authors.forename: Shogo
authors.initials: S
authors.lastname: Tajima
authors.affiliation: Department of Cell Biology and Anatomy, Hamamatsu University School of Medicine Shizuoka, Japan.
authors.forename: Michihiko
authors.initials: M
authors.lastname: Waki
authors.affiliation: Department of Gastroenterology, Fujieda Municipal General Hospital Shizuoka, Japan.
authors.forename: Akihiko
authors.initials: A
authors.lastname: Ohata
authors.affiliation: Department of Pathology, Fujieda Municipal General Hospital Shizuoka, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Koda
authors.affiliation: Department of Gastroenterology, Fujieda Municipal General Hospital Shizuoka, Japan.
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Maruyama
mesh_terms: D000196:Actinomycosis / Q000150:complications* / Q000473:pathology*; D000369:Aged, 80 and over; D005260:Female; D005756:Gastritis / Q000382:microbiology* / Q000473:pathology*; D006099:Granuloma / Q000382:microbiology / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000382:microbiology / Q000473:pathology
keywords: Xanthogranuloma; actinomycosis; stomach