title: Hemophagocytic Lymphohistiocytosis (HLH) in Children Presenting as Liver Disease.
abstract: Hemophagocytic lymphohistiocytosis (HLH) is a rare acute hyperinflammatory condition presenting with high fever, pancytopenia, splenomegaly with the pathologic finding of hemophagocytic lymphohistiocytosis in bone marrow and other tissues. Predominant hepatic manifestations at presentation are rare. We report a series of three cases which showcase the spectrum of liver disease as presentation in hemophagocytic lymphohistiocytosis.
authors.affiliation: Pediatric Liver Clinic, B.J. Wadia Hospital for Children, Mumbai, India.
authors.forename: Nomisha
authors.initials: N
authors.lastname: Amin
authors.affiliation: Pediatric Liver Clinic, B.J. Wadia Hospital for Children, Mumbai, India.
authors.forename: Ira
authors.initials: I
authors.lastname: Shah
authors.affiliation: Pediatric Liver Clinic, B.J. Wadia Hospital for Children, Mumbai, India.
authors.forename: Sushmita
authors.initials: S
authors.lastname: Bhatnagar
keywords: CMV, cytomegalovirus; EBV, Epstein Barr virus; HLH; HLH, hemophagocytic lymphohistiocytosis; LKM, liver–kidney-microsomal; MAS, macrophage activation syndrome; PT, prothrombin time; PTT, partial thromboplastin time; VAHS, virus associated HLH; children; liver disease