title: [Evaluation of myocardial perfusion by single-photon emission CT in the treatment with beta-adrenoblockers and calcium channel blockers].
abstract: Single-photon emission CT of the heart was used to observe coronary blood flow and reveal the maximum perfusion region in patients with coronary heart disease (CHD) treated with beta-adrenoblockers and calcium channel blockers. Dynamic observation showed changes and redistribution of myocardial perfusion. Specific features of coronary blood flow were demonstrated depending on the therapeutic modality (beta-blocker metoprolol, calcium channel blocker amlodipine). Parameters of prognostic value were identified depending on the effectiveness of the agents used. This approach together with the traditional nosological one to the choice of CHD therapy permits to individualize the therapeutic influence depending on myocardial micriocirculatory features, such as the spread and depth of perfusion disturbances.
authors.forename: R G
authors.initials: RG
authors.lastname: Makiev
authors.forename: A E
authors.initials: AE
authors.lastname: Alanichev
authors.forename: P G
authors.initials: PG
authors.lastname: Shachnovich
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Rakhimova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Ovchinnikov
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Fisun
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D017311:Amlodipine / Q000008:administration & dosage*; D060050:Angina, Stable / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D002121:Calcium Channel Blockers / Q000008:administration & dosage; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000187:drug effects; D016903:Drug Monitoring / Q000379:methods; D005260:Female; D006334:Heart Function Tests / Q000379:methods; D006801:Humans; D008297:Male; D008790:Metoprolol / Q000008:administration & dosage*; D008833:Microcirculation / Q000187:drug effects*; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging / Q000379:methods; D011379:Prognosis; D012720:Severity of Illness Index; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D002121:Calcium Channel Blockers; D017311:Amlodipine; D008790:Metoprolol