title: Erectile dysfunction in urethral stricture and pelvic fracture urethral injury patients: diagnosis, treatment, and outcomes.
abstract: Urethral stricture disease, pelvic fracture urethral injury (PFUI), and their various treatment options are associated with erectile dysfunction (ED). The etiology of urethral stricture disease is multifactorial and includes trauma, inflammatory, and iatrogenic causes. Posterior urethral injuries are commonly associated with pelvic fractures. There is a spectrum in the severity of both conditions and this directly impacts the treatment options offered by the surgeon. Many published studies focus on the treatment outcomes and the relatively high recurrence rates after surgical repair. This communication reviews the current knowledge of the association between ED and urethral stricture disease, as well as PFUI. The incidence, pathophysiology, and clinical ramifications of both conditions on sexual function are discussed. The treatment options for ED in those patients are reviewed and summarized.
authors.affiliation: Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA.
authors.forename: P
authors.initials: P
authors.lastname: Sangkum
authors.affiliation: Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA.
authors.forename: J
authors.initials: J
authors.lastname: Levy
authors.affiliation: Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA.
authors.forename: F A
authors.initials: FA
authors.lastname: Yafi
authors.affiliation: Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA.
authors.forename: W J G
authors.initials: WJ
authors.lastname: Hellstrom
mesh_terms: D007172:Erectile Dysfunction / Q000175:diagnosis* / Q000628:therapy*; D050723:Fractures, Bone / Q000601:surgery*; D006801:Humans; D008297:Male; D010384:Pelvic Bones / Q000293:injuries / Q000601:surgery; D010388:Pelvis / Q000293:injuries / Q000601:surgery; D019935:Penile Implantation; D058986:Phosphodiesterase 5 Inhibitors / Q000627:therapeutic use; D016896:Treatment Outcome; D014521:Urethra / Q000293:injuries / Q000503:physiopathology / Q000601:surgery; D014525:Urethral Stricture / Q000503:physiopathology* / Q000628:therapy*
chemical_list: D058986:Phosphodiesterase 5 Inhibitors
keywords: erectile dysfunction; pelvic fracture urethral injury; penile revascularization; urethral stricture disease