title: Antibody conjugates bispecific for intercellular adhesion molecule 1 and allergen prevent migration of allergens through respiratory epithelial cell layers.
authors.affiliation: Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
authors.forename: Christoph
authors.initials: C
authors.lastname: Madritsch
authors.affiliation: Department of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.
authors.forename: Julia
authors.initials: J
authors.lastname: Eckl-Dorna
authors.affiliation: Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
authors.forename: Katharina
authors.initials: K
authors.lastname: Blatt
authors.affiliation: Division of Cellular and Molecular Pathophysiology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
authors.forename: Isabella
authors.initials: I
authors.lastname: Ellinger
authors.affiliation: Institute of Environmental Health, Center of Public Health, Medical University of Vienna, Vienna, Austria.
authors.forename: Michael
authors.initials: M
authors.lastname: Kundi
authors.affiliation: Department of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria.
authors.forename: Verena
authors.initials: V
authors.lastname: Niederberger
authors.affiliation: Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
authors.forename: Peter
authors.initials: P
authors.lastname: Valent
authors.affiliation: Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
authors.forename: Rudolf
authors.initials: R
authors.lastname: Valenta
authors.affiliation: Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria. Electronic address: sabine.flicker@meduniwien.ac.at.
authors.forename: Sabine
authors.initials: S
authors.lastname: Flicker
mesh_terms: D000485:Allergens / Q000737:chemistry / Q000276:immunology*; D018033:Antibodies, Bispecific / Q000096:biosynthesis* / Q000737:chemistry; D001491:Basophils / Q000187:drug effects / Q000276:immunology / Q000473:pathology; D001710:Biotin / Q000737:chemistry; D001980:Bronchi / Q000187:drug effects / Q000276:immunology / Q000473:pathology; D002460:Cell Line; D004847:Epithelial Cells / Q000187:drug effects / Q000276:immunology / Q000473:pathology; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D018796:Immunoconjugates / Q000737:chemistry / Q000494:pharmacology*; D018799:Intercellular Adhesion Molecule-1 / Q000737:chemistry / Q000276:immunology*; D008856:Microscopy, Fluorescence; D010940:Plant Proteins / Q000037:antagonists & inhibitors* / Q000276:immunology; D061251:Primary Cell Culture; D021381:Protein Transport / Q000187:drug effects; D020545:Respiratory Mucosa / Q000187:drug effects / Q000276:immunology / Q000473:pathology; D019809:Streptavidin / Q000737:chemistry
chemical_list: D000485:Allergens; D018033:Antibodies, Bispecific; C573420:ICAM1 protein, human; D018796:Immunoconjugates; C084984:PHLPII protein, Phleum pratense; D010940:Plant Proteins; D018799:Intercellular Adhesion Molecule-1; D001710:Biotin; D019809:Streptavidin