title: Long-term survival of a semi-constrained implant following revision for infection.
abstract: Revision total knee arthroplasty (TKA) in prosthetic joint infections (PJI) is a challenging problem. We evaluated our institutional experience with a semi-constrained implant placed in a PJI setting. Seventy-eight TKAs in 75 patients with a history of a PJI were identified. The average follow-up was 7.5 years. Twenty-three (29%) underwent repeat revision surgery. Five and 10 year survivals were 71% and 64%, respectively. The most common reason for repeat revision surgery was recurrent infection (78%). Smoking and elevated BMI increased the risk of repeat revision surgery. Significant improvements were maintained long term in pain and range of motion (P < 0.01 and P = 0.02). In the absence of repeat infection, long term pain relief and improved function may be expected with the semi-constrained implant.
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Wilke
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Eric
authors.initials: E
authors.lastname: Wagner
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Robert
authors.initials: R
authors.lastname: Trousdale
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001168:Arthritis; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects* / Q000379:methods*; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007239:Infections / Q000209:etiology* / Q000601:surgery; D007720:Knee Prosthesis / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011474:Prosthesis Design; D011475:Prosthesis Failure; D016059:Range of Motion, Articular; D012042:Registries; D012086:Reoperation / Q000379:methods*; D012189:Retrospective Studies; D012907:Smoking / Q000009:adverse effects; D013997:Time Factors; D016896:Treatment Outcome
keywords: infection; revision total knee arthroplasty; semi-constrained implant; total condylar III knee