title: Sedentary Behavior in Individuals With Diabetic Chronic Kidney Disease and Maintenance Hemodialysis.
abstract: OBJECTIVE
  The objective of this study was to examine whether more advanced kidney failure is associated with sedentary behavior and whether demographics, comorbidity, nutritional, and inflammatory markers explain this association.
  
  
  METHODS
  Observational study.
  
  
  METHODS
  Outpatients recruited from outpatient clinics and dialysis units.
  
  
  METHODS
  One hundred sixty patients with chronic kidney disease (CKD) or receiving maintenance hemodialysis (MHD).
  
  
  METHODS
  Standardized questionnaires including Baecke physical activity questionnaire, standardized anthropometry examination, and blood draw.
  
  
  METHODS
  Sedentary behavior (defined as answering "very often" for "during leisure time I watch television" or answering "never" for "during leisure time I walk") and being physically active (top 25th percentile of the total Baecke score).
  
  
  RESULTS
  Nineteen percent of CKD and 50% of MHD patients were sedentary (P < .001) and 38.8% of CKD and 11.3% of MHD patients were physically active. In separate multivariable logistic regression models, compared with CKD patients, MHD patients were more sedentary (odds ratio 3.84; 95% confidence interval, 1.18-12.51) and less physically active (odds ratio 0.07; 95% confidence interval 0.01-0.40) independent of demographics, comorbidity, smoking, body size, serum high sensitivity C-reactive protein (hsCRP) and albumin. Congestive heart failure, peripheral vascular disease, and higher body mass index were independently associated with sedentary behavior, whereas younger age, lower body mass index, lower serum hsCRP, and higher serum albumin were associated with being physically active.
  
  
  CONCLUSIONS
  Sedentary behavior is highly prevalent among diabetic CKD or MHD patients. The strong association of MHD status with sedentary behavior is not explained by demographics, smoking, comorbidity, nutritional, and inflammatory markers. Interventions targeting obesity might improve sedentary behavior and physical activity, whereas interventions targeting inflammation might improve physical activity in these populations.
authors.affiliation: Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah; Department of Physical Therapy, University of Utah College of Health, Salt Lake City, Utah.
authors.forename: Natalie
authors.initials: N
authors.lastname: Anderton
authors.affiliation: Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Ajay
authors.initials: A
authors.lastname: Giri
authors.affiliation: Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Guo
authors.initials: G
authors.lastname: Wei
authors.affiliation: Department of Physical Therapy, University of Utah College of Health, Salt Lake City, Utah.
authors.forename: Robin L
authors.initials: RL
authors.lastname: Marcus
authors.affiliation: Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Xiaorui
authors.initials: X
authors.lastname: Chen
authors.affiliation: Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Terrence
authors.initials: T
authors.lastname: Bjordahl
authors.affiliation: Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Arsalan
authors.initials: A
authors.lastname: Habib
authors.affiliation: Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah.
authors.forename: Jenice
authors.initials: J
authors.lastname: Herrera
authors.affiliation: Department of Medicine, University of Utah School of Medicine, Salt Lake City, Utah; Salt Lake City Veterans Affairs Healthcare System, Salt Lake City, Utah. Electronic address: Srinivasan.Beddhu@hsc.utah.edu.
authors.forename: Srinivasan
authors.initials: S
authors.lastname: Beddhu
mesh_terms: D000368:Aged; D015897:Comorbidity; D048909:Diabetes Complications / Q000097:blood / Q000150:complications*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000097:blood; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000097:blood / Q000150:complications*; D057185:Sedentary Behavior; D011795:Surveys and Questionnaires