title: Hearing preservation in vestibular schwannoma management.
abstract: OBJECTIVE
  To compare hearing preservation between stereotactic radiotherapy (SRT) and conservative treatment of patients with unilateral vestibular schwannoma.
  
  
  METHODS
  Retrospective case series comparing hearing outcomes of patients with a unilateral vestibular schwannoma managed conservatively or with stereotactic radiotherapy in a tertiary care academic centre.
  
  
  METHODS
  
  
  
  METHODS
  Tumor database patients with American Academy of Otolaryngology Head and Neck Surgery Class A or B hearing at the onset of study. Stereotactic radiotherapy patients were predominantly those who failed conservative management.
  
  
  METHODS
  Audiometric pure tone averages and speech discrimination scores as well as patient demographics, tumor location, size and growth were extracted.
  
  
  METHODS
  Hearing outcome measures were: 1) Hearing Preservation, i.e. no drop from Class A/B to Class C/D hearing, 2) Hearing Survival of Class A/B hearing in months, 3) Audiometric Pure Tone Averages, Difference between post-treatment and pre-treatment, and 4) Speech Discrimination Score Difference (pre-treatment-post treatment). Survival analysis and non-parametric tests were used for hearing outcome measures, with multiple covariates tested.
  
  
  RESULTS
  Overall, serviceable hearing preservation among the 123 patients was 51%. The median hearing survival time was 46 months (mean 59 months). The Pure Tone averages and Speech Discrimination score differences were 16 dB and 82% respectively over a median follow-up time of 43 months. No significant difference was found between the conservative and SRT groups in any hearing outcome. Class A patients showed far better hearing survival than Class B patients.
  
  
  CONCLUSIONS
  No significant difference was demonstrated as to measures of hearing outcomes between stereotactic radiotherapy and conservative management. Excellent existing hearing appears to be the best predictor of long term hearing survival in the cohort studied.
authors.affiliation: Maritime Lateral Skull Base Clinic, Division Otolaryngology, Dalhousie University 3rd Floor Dickson Building, QEII VG site, 1278 Tower Road, Halifax, NS.
authors.forename: Anna
authors.initials: A
authors.lastname: Elliott
authors.affiliation: Maritime Lateral Skull Base Clinic, Division of Neurosurgery, Dalhousie University, QEII Halifax Infirmary Site, 1796 Summer Street, Halifax, NS.
authors.forename: Andrea L O
authors.initials: AL
authors.lastname: Hebb
authors.affiliation: Maritime Lateral Skull Base Clinic, Division of Neurosurgery, Dalhousie University, QEII Halifax Infirmary Site, 1796 Summer Street, Halifax, NS.
authors.forename: Simon
authors.initials: S
authors.lastname: Walling
authors.affiliation: Maritime Lateral Skull Base Clinic, Division Otolaryngology, Dalhousie University 3rd Floor Dickson Building, QEII VG site, 1278 Tower Road, Halifax, NS.
authors.forename: David P
authors.initials: DP
authors.lastname: Morris
authors.affiliation: Maritime Lateral Skull Base Clinic, Division Otolaryngology, Dalhousie University 3rd Floor Dickson Building, QEII VG site, 1278 Tower Road, Halifax, NS. Electronic address: m.bance@dal.ca.
authors.forename: Manohar
authors.initials: M
authors.lastname: Bance
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001301:Audiometry, Pure-Tone; D005260:Female; D005500:Follow-Up Studies; D006309:Hearing / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000503:physiopathology / Q000601:surgery*; D016634:Radiosurgery / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult