title: [Development of antiviral treatments for chronic hepatitis C].
abstract: The antiviral therapy for chronic hepatitis C has been developed since HCV was discovered in 1989. As for the patients with genotype 1, sustained virological response rate by interferon monotherapy was less than 20% in 1990's; the rate has been improved today to 85% by direct-acting antivirals. The prevention of development of liver cirrhosis and hepatocellular carcinoma will be expected.
authors.forename: Hidetaka
authors.initials: H
authors.lastname: Fujinaiga
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Koike
mesh_terms: D019698:Hepatitis C, Chronic / Q000188:drug therapy*; D006801:Humans; D007372:Interferons / Q000494:pharmacology; D012254:Ribavirin / Q000494:pharmacology
chemical_list: D012254:Ribavirin; D007372:Interferons