title: A ratiometric fluorescent probe for in situ quantification of basal mitochondrial hypochlorite in cancer cells.
abstract: A ratiometric fluorescent probe () for ClO(-) based on the conjugate of coumarin-rhodamine was presented, which could sense ClO(-) with fast response (within 5 s), high sensitivity and excellent selectivity. More importantly, is the first mitochondria-targeted ratiometric fluorescent probe to image exogenous and endogenous ClO(-).
authors.affiliation: Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry Sichuan University, 29, Wangjiang Road, Chengdu, Sichuan Province, P. R. China. kli@scu.edu.cn xqyu@scu.edu.cn.
authors.forename: Ji-Ting
authors.initials: JT
authors.lastname: Hou
authors.forename: Kun
authors.initials: K
authors.lastname: Li
authors.forename: Jin
authors.initials: J
authors.lastname: Yang
authors.forename: Kang-Kang
authors.initials: KK
authors.lastname: Yu
authors.forename: Ye-Xin
authors.initials: YX
authors.lastname: Liao
authors.forename: Yu-Zhao
authors.initials: YZ
authors.lastname: Ran
authors.forename: Yan-Hong
authors.initials: YH
authors.lastname: Liu
authors.forename: Xue-Dong
authors.initials: XD
authors.lastname: Zhou
authors.forename: Xiao-Qi
authors.initials: XQ
authors.lastname: Yu
mesh_terms: D000818:Animals; D002460:Cell Line; D003374:Coumarins / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D006997:Hypochlorous Acid / Q000737:chemistry* / Q000378:metabolism*; D051379:Mice; D008928:Mitochondria / Q000378:metabolism*; D012235:Rhodamines / Q000737:chemistry
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes; D012235:Rhodamines; D006997:Hypochlorous Acid; C030123:coumarin