title: Severe, very early onset pre-eclampsia associated with liquorice consumption.
abstract: BACKGROUND
  We present the case of very early onset pre-eclampsia, possibly aggravated by liquorice consumption.
  
  
  METHODS
  An 18-year-old healthy primigravida presented with high blood pressure and proteinuria at 18 weeks gestation. She had a strong family history of pre-eclampsia and was consuming considerable amounts of liquorice. A diagnosis of severe pre-eclampsia/hemolysis, elevated liver enzymes, and low platelet count was confirmed. The pregnancy was terminated. Extensive investigation ruled out underlying diseases and autopsy revealed a normal fetus. In three consequtive pregnancies, she developed milder forms of pre-eclampsia.
  
  
  CONCLUSIONS
  In healthy women with a familial/genetic susceptibility for pre-eclampsia, liquorice consumption may aggravate the course of the disease.
authors.affiliation: Department of Obstetrics and Gynecology .
authors.forename: Dögg
authors.initials: D
authors.lastname: Hauksdottir
authors.forename: Helga Agusta
authors.initials: HA
authors.lastname: Sigurjonsdottir
authors.forename: Margret
authors.initials: M
authors.lastname: Arnadottir
authors.forename: Reynir T
authors.initials: RT
authors.lastname: Geirsson
mesh_terms: D000032:Abortion, Therapeutic; D000293:Adolescent; D005260:Female; D020022:Genetic Predisposition to Disease; D006035:Glycyrrhiza / Q000009:adverse effects*; D006801:Humans; D011225:Pre-Eclampsia / Q000139:chemically induced* / Q000175:diagnosis*; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011507:Proteinuria / Q000139:chemically induced
keywords: Hypertension; Intrauterine growth restriction; Liqourice; Pre-eclampsia; Pregnancy