title: Cognitive functioning and walking speed in older adults as predictors of limitations in self-reported instrumental activity of daily living: prospective findings from the Obu Study of Health Promotion for the Elderly.
abstract: Our aim was to determine whether baseline measures of cognitive functioning, walking speed, and depressive status are independent predictors of limitations in instrumental activities of daily living (IADL) in older adults. The cross-sectional study involved 1329 community-dwelling adults, aged 75 years or older. At baseline, the Mini-Mental State Examination (MMSE), Symbol Digit Substitution Test (SDST), Geriatric Depressive Scale (GDS), and a word list memory task were completed, and self-reported IADLs and walking speed were recorded. The longitudinal study involved 948 participants without baseline IADL limitation, which was assessed at baseline and 15-month follow up, using the three Kihon Checklist subitems. In cross-sectional analyses, participants with IADL limitation demonstrated greater GDS scores, slower walking speeds, and lower MMSE, word list memory task, and SDST (only for women) scores relative to those without IADL limitation. In the longitudinal analyses, baseline walking speed (men: OR 0.98; women: OR 0.97, p<0.05) and word list memory task scores (men: OR 0.84; women: OR 0.83, p<0.05) in both sexes and SDST scores in women (OR 0.96, p=0.04) were independent predictors of subsequent IADL limitation. Walking speed, memory, and processing speed may be independent predictors of IADL limitation in older adults.
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. makizako@ncgg.go.jp.
authors.forename: Hyuma
authors.initials: H
authors.lastname: Makizako
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. shimada@ncgg.go.jp.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Shimada
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. take-d@ncgg.go.jp.
authors.forename: Takehiko
authors.initials: T
authors.lastname: Doi
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. k-tsutsu@ncgg.go.jp.
authors.forename: Kota
authors.initials: K
authors.lastname: Tsutsumimoto
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. leesuys@ncgg.go.jp.
authors.forename: Sangyoon
authors.initials: S
authors.lastname: Lee
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. ryo-h@ncgg.go.jp.
authors.forename: Ryo
authors.initials: R
authors.lastname: Hotta
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. sho-n@ncgg.go.jp.
authors.forename: Sho
authors.initials: S
authors.lastname: Nakakubo
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. harada-k@ncgg.go.jp.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Harada
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. leesuys@ncgg.go.jp.
authors.forename: Sungchul
authors.initials: S
authors.lastname: Lee
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. bae-sr@ncgg.go.jp.
authors.forename: Seongryu
authors.initials: S
authors.lastname: Bae
authors.affiliation: Department of Functioning Activation, Center for Gerontology and Social Science, National Centerfor Geriatrics and Gerontology, 7-430 Morioka-cho, Obu, Aichi 474-8511, Japan. harada-k@ncgg.go.jp.
authors.forename: Kenji
authors.initials: K
authors.lastname: Harada
authors.affiliation: Research Institute, National Center for Geriatrics and Gerontology, 7-430 Morioka-cho, Obu,Aichi 474-8511, Japan. suzutaka@ncgg.go.jp.
authors.forename: Takao
authors.initials: T
authors.lastname: Suzuki
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006293:Health Promotion; D006801:Humans; D007564:Japan; D008297:Male; D009483:Neuropsychological Tests; D011446:Prospective Studies; D057566:Self Report; D016138:Walking / Q000502:physiology*