title: Hospital outcomes of extremely low birth weight infants after introduction of donor milk to supplement mother's milk.
abstract: OBJECTIVE
  This study evaluated the impact of an exclusive human milk diet to nourish extremely low birth weight infants in the neonatal intensive care unit.
  
  
  METHODS
  This multicenter pre-post retrospective study included all inborn infants <1,000 g admitted to four Level IV neonatal intensive care units either before or after implementing a donor human milk policy. The feeding protocol was unchanged in both periods. Collected data included maternal/infant demographics, infant clinical data, and enteral intake as mother's own milk, donor milk, and formula.
  
  
  RESULTS
  Two hundred one infants were enrolled. Infant growth and other clinical outcomes were similar in both groups. Exposure to mother's own milk at discharge was not different. Median time in oxygen and duration of mechanical ventilation were significantly higher among formula-fed infants (63 versus 192 hours [p=0.046] and 24 versus 60 hours [p=0.016], respectively).
  
  
  CONCLUSIONS
  Our results add evidence supporting the safety of donor milk. This study also found an association between exposure to formula in preterm infants and the requirement for respiratory support, a finding that warrants further investigation.
authors.affiliation: 1 Department of Paediatrics, Hospital de la Santa Creu i Sant Pau , Barcelona. Spain .
authors.forename: Sergio
authors.initials: S
authors.lastname: Verd
authors.forename: Roser
authors.initials: R
authors.lastname: Porta
authors.forename: Francesc
authors.initials: F
authors.lastname: Botet
authors.forename: Antonio
authors.initials: A
authors.lastname: Gutiérrez
authors.forename: Gemma
authors.initials: G
authors.lastname: Ginovart
authors.forename: Ana Herranz
authors.initials: AH
authors.lastname: Barbero
authors.forename: Anna
authors.initials: A
authors.lastname: Ciurana
authors.forename: Isabel Iglesias
authors.initials: II
authors.lastname: Plata
mesh_terms: D001942:Breast Feeding / Q000379:methods / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D041943:Infant Formula; D007227:Infant Nutritional Physiological Phenomena; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000453:epidemiology* / Q000276:immunology; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data*; D008297:Male; D017784:Milk Banks / Q000706:statistics & numerical data*; D008895:Milk, Human / Q000276:immunology*; D009035:Mothers; D061352:Pasteurization; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D016896:Treatment Outcome