title: The relationship of TIMI risk index with SYNTAX and Gensini risk scores in predicting the extent and severity of coronary artery disease in patients with STEMI undergoing primary percutaneous coronary intervention.
abstract: OBJECTIVE
  The prognostic value of the Global Registry of Acute Coronary Events (GRACE) risk score (GRS) and the Thrombolysis in Myocardial Infarction (TIMI) risk index (TRI) have been reported in patients with coronary artery disease (CAD). In this study, we sought to evaluate the association between TRI and the extent and severity of CAD evaluated by SYNTAX score (SS) and Gensini score in patients with ST elevation myocardial infarction (STEMI).
  
  
  METHODS
  A total of 290 patients with STEMI were included in the study. GRS and TRI were calculated on admission using specified variables. The extent and severity of CAD were evaluated using the SS and Gensini scores. The patients were divided into low (TRI ⩽19), intermediate (TRI 19-30), and high (TRI ⩾30) risk groups. A Pearson correlation analysis was used for the relationship between TRI, GRS, Gensini score and SS.
  
  
  RESULTS
  There were significant differences in the mean age (p < 0.001), admission heart rate (p < 0.001), admission systolic blood pressure (p = 0.009), SS (p < 0.001), GRS (p < 0.001) and in-hospital major adverse cardiac events (MACE) in all patients between the low, intermediate and high TRI risk groups. There was a positive significant correlation between TRI and SS (r = 0.24, p < 0.001), Gensini score (r = 0.18, p = 0.002), GRS (r = 0.74, p = 0.001) and in-hospital MACE (r = 0.29, p < 0.001).
  
  
  CONCLUSIONS
  TRI is significantly related to SS and Gensini score in predicting the extent and severity of CAD in patients with STEMI.
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır 21280, Turkey halitacet@gmail.com.
authors.forename: Halit
authors.initials: H
authors.lastname: Acet
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Faruk
authors.initials: F
authors.lastname: Ertaş
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Mehmet Zihni
authors.initials: MZ
authors.lastname: Bilik
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Mesut
authors.initials: M
authors.lastname: Aydın
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Yüksel
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Nihat
authors.initials: N
authors.lastname: Polat
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Abdulkadir
authors.initials: A
authors.lastname: Yıldız
authors.affiliation: Faculty of Medicine, Department of Cardiology, Izmir Universty, İzmir, Turkey.
authors.forename: Ferhat
authors.initials: F
authors.lastname: Özyurtlu
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Mehmet Ata
authors.initials: MA
authors.lastname: Akıl
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Leyla
authors.initials: L
authors.lastname: Çiftçi
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Özbek
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Sait
authors.initials: S
authors.lastname: Alan
authors.affiliation: Faculty of Medicine, Department of Cardiology, Dicle Universty, Diyarbakır, Turkey.
authors.forename: Nizamettin
authors.initials: N
authors.lastname: Toprak
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology; D003324:Coronary Artery Disease / Q000503:physiopathology*; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology*; D062645:Percutaneous Coronary Intervention; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods; D012720:Severity of Illness Index
keywords: GRACE risk score; Gensini score; STEMI; SYNTAX score; TIMI risk index; TIMI risk score