title: Mechanism of the cytotoxic action of immunophototoxin 4D5scFV-miniSOG on HER2/neu-positive cancer cells.
authors.affiliation: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, Moscow, 117997, Russia, gmb@ibch.ru.
authors.forename: G M
authors.initials: GM
authors.lastname: Proshkina
authors.forename: K E
authors.initials: KE
authors.lastname: Mironova
authors.forename: S M
authors.initials: SM
authors.lastname: Deyev
authors.forename: R V
authors.initials: RV
authors.lastname: Petrov
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D034961:Antigens, Nuclear / Q000378:metabolism*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D053148:Caspase 3 / Q000378:metabolism; D016923:Cell Death / Q000187:drug effects / Q000502:physiology / Q000528:radiation effects; D045744:Cell Line, Tumor; D005420:Flavoproteins / Q000494:pharmacology*; D006801:Humans; D008027:Light; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000494:pharmacology*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism*; D011993:Recombinant Fusion Proteins / Q000494:pharmacology*; D057127:Single-Chain Antibodies / Q000494:pharmacology*
chemical_list: D034961:Antigens, Nuclear; D053148:Caspase 3; D005420:Flavoproteins; D009419:Nerve Tissue Proteins; D017319:Photosensitizing Agents; D018719:Erb-b2 Receptor Tyrosine Kinases; D011993:Recombinant Fusion Proteins; D057127:Single-Chain Antibodies; C000603949:4D5scFv-miniSOG immunophototoxin; C506808:neuronal nuclear antigen NeuN, human; C508053:ERBB2 protein, human; C505407:CASP3 protein, human