title: Stereoselective nickel-catalyzed [2+2] cycloadditions of ene-allenes.
abstract: A stereoselective nickel-catalyzed [2+2] cycloaddition of ene-allenes is reported. This transformation encompasses a broad range of ene-allene substrates, thus providing efficient access to fused cyclobutanes from easily accessed π-components. A simple and inexpensive first-row catalytic system comprised of [Ni(cod)2 ] and dppf was used in this process, thus constituting an attractive approach to synthetically challenging cyclobutane frameworks under mild reaction conditions.
authors.affiliation: Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 (USA).
authors.forename: Njamkou N
authors.initials: NN
authors.lastname: Noucti
authors.forename: Erik J
authors.initials: EJ
authors.lastname: Alexanian
keywords: alkenes; allenes; carbocycles; cycloaddition; nickel