title: Functional network in posttranslational modifications: Glyco-Net in Glycoconjugate Data Bank.
abstract: Elucidating pathways related to posttranslational modifications (PTMs) such as glycosylation is of growing importance in post-genome science and technology. Graphical networks describing the relationships among glycan-related molecules, including genes, proteins, lipids, and various biological events, are considered extremely valuable and convenient tools for the systematic investigation of PTMs. Glyco-Net (http://bibi.sci.hokudai.ac.jp/functions/) can dynamically make network figures among various biological molecules and biological events. A certain molecule or event is expressed with a node, and the relationship between the molecule and the event is indicated by arrows in the network figures. In this chapter, we mention the features and current status of the Glyco-Net and a simple example of the search with the Glyco-Net.
authors.affiliation: Graduate School of Life Sciences, Hokkaido University, 1-204, Open Laboratory in Central Campus, Sapporo, 060-0812, Japan, n.muller@nifty.ne.jp.
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Miura
authors.forename: Takuya
authors.initials: T
authors.lastname: Okada
authors.forename: Daisuke
authors.initials: D
authors.lastname: Murayama
authors.forename: Kazuko
authors.initials: K
authors.lastname: Hirose
authors.forename: Taku
authors.initials: T
authors.lastname: Sato
authors.forename: Ryo
authors.initials: R
authors.lastname: Hashimoto
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Fukushima
mesh_terms: D016208:Databases, Factual; D006001:Glycoconjugates / Q000737:chemistry*; D053858:Metabolic Networks and Pathways; D011499:Protein Processing, Post-Translational; D012984:Software
chemical_list: D006001:Glycoconjugates