title: Establishing a national knowledge translation and generation network in kidney disease: the CAnadian KidNey KNowledge TraNslation and GEneration NeTwork.
abstract: Patients with chronic kidney disease (CKD) do not always receive care consistent with guidelines, in part due to complexities in CKD management, lack of randomized trial data to inform care, and a failure to disseminate best practice. At a 2007 conference of key Canadian stakeholders in kidney disease, attendees noted that the impact of Canadian Society of Nephrology (CSN) guidelines was attenuated given limited formal linkages between the CSN Clinical Practice Guidelines Group, kidney researchers, decision makers and knowledge users, and that further knowledge was required to guide care in patients with kidney disease. The idea for the Canadian Kidney Knowledge Translation and Generation Network (CANN-NET) developed from this meeting. CANN-NET is a pan-Canadian network established in partnership with CSN, the Kidney Foundation of Canada and other professional societies to improve the care and outcomes of patients with and at risk for kidney disease. The initial priority areas for knowledge translation include improving optimal timing of dialysis initiation, and increasing the appropriate use of home dialysis. Given the urgent need for new knowledge, CANN-NET has also brought together a national group of experienced Canadian researchers to address knowledge gaps by encouraging and supporting multicentre randomized trials in priority areas, including management of cardiovascular disease in patients with kidney failure.
authors.affiliation: Department of Medicine, University of Calgary, Calgary, Alberta Canada ; Department of Community Health Sciences, University of Calgary, Calgary, Alberta Canada ; Libin Cardiovascular Institute and Institute for Population Health, University of Calgary, Kragujevac, Alberta Canada.
authors.forename: Braden
authors.initials: B
authors.lastname: Manns
authors.affiliation: Department of Medicine, Memorial Medical School, St John's, NL Canada.
authors.forename: Brendan
authors.initials: B
authors.lastname: Barrett
authors.affiliation: Family Medicine and Public Health, University of Toronto, Toronto, Canada.
authors.forename: Michael
authors.initials: M
authors.lastname: Evans
authors.affiliation: Division of Nephrology, Department of Medicine, University of Western Ontario, London, ON Canada.
authors.forename: Amit
authors.initials: A
authors.lastname: Garg
authors.affiliation: Department of Medicine, University of Calgary, Calgary, Alberta Canada ; Department of Community Health Sciences, University of Calgary, Calgary, Alberta Canada ; Libin Cardiovascular Institute and Institute for Population Health, University of Calgary, Kragujevac, Alberta Canada.
authors.forename: Brenda
authors.initials: B
authors.lastname: Hemmelgarn
authors.affiliation: Department of Medicine, University of Saskatchewan, Saskatoon, SK Canada.
authors.forename: Joanne
authors.initials: J
authors.lastname: Kappel
authors.affiliation: Department of Medicine, University of Alberta, Edmonton, Alberta Canada.
authors.forename: Scott
authors.initials: S
authors.lastname: Klarenbach
authors.affiliation: Department of Medicine, University of Montreal, Montreal, Quebec Canada.
authors.forename: Francois
authors.initials: F
authors.lastname: Madore
authors.affiliation: Department of Medicine, Memorial Medical School, St John's, NL Canada.
authors.forename: Patrick
authors.initials: P
authors.lastname: Parfrey
authors.affiliation: Department of Community Health Sciences, University of Calgary, Calgary, Alberta Canada ; Division of Pediatric Nephrology, Department of Pediatrics, Faculty of Medicine, University of Calgary, Calgary, Alberta Canada ; Alberta Children's Hospital Research Institute for Child and Maternal Health, Calgary, Alberta Canada.
authors.forename: Susan
authors.initials: S
authors.lastname: Samuel
authors.affiliation: Department of Medicine, Dalhousie University, Halifax, Nova Scotia Canada.
authors.forename: Steven
authors.initials: S
authors.lastname: Soroka
authors.affiliation: Division of Nephrology, Department of Medicine, University of Western Ontario, London, ON Canada ; Medicine, Centre de Recherche du Centre Hospitalier de l`Université de Montréal, Montréal, QC Canada.
authors.forename: Rita
authors.initials: R
authors.lastname: Suri
authors.affiliation: Department of Medicine, University of Alberta, Edmonton, Alberta Canada.
authors.forename: Marcello
authors.initials: M
authors.lastname: Tonelli
authors.affiliation: Division of Nephrology, St. Michael's Hospital and the University of Toronto, Toronto, ON Canada ; Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, ON Canada.
authors.forename: Ron
authors.initials: R
authors.lastname: Wald
authors.affiliation: Division of Nephrology, McMaster University, Hamilton, Ontario Canada.
authors.forename: Michael
authors.initials: M
authors.lastname: Walsh
authors.affiliation: Department of Pediatrics, McGill University Health Centre, Montreal, QC Canada.
authors.forename: Michael
authors.initials: M
authors.lastname: Zappitelli
keywords: Clinical trials; Kidney disease; Knowledge translation