title: The limits of serial surveillance cultures in predicting clearance of colonization with carbapenemase-producing Enterobacteriaceae.
abstract: An accepted practice for patients colonized with multidrug-resistant organisms is to discontinue contact precautions following 3 consecutive negative surveillance cultures. Our experience with surveillance cultures to detect persistent carbapenemase-producing Enterobacteriaceae (CPE) colonization suggests that extrapolation of this practice to CPE-colonized patients may not be appropriate.
authors.affiliation: 1Division of Infectious Diseases & International Health,Department of Medicine,University of Virginia Health System,Charlottesville,Virginia.
authors.forename: Jessica D
authors.initials: JD
authors.lastname: Lewis
authors.affiliation: 2Division of Pulmonary & Critical Care Medicine,Department of Medicine,University of Virginia Health System,Charlottesville,Virginia.
authors.forename: Kyle B
authors.initials: KB
authors.lastname: Enfield
authors.affiliation: 1Division of Infectious Diseases & International Health,Department of Medicine,University of Virginia Health System,Charlottesville,Virginia.
authors.forename: Amy J
authors.initials: AJ
authors.lastname: Mathers
authors.affiliation: 3Office of Hospital Epidemiology/Infection Prevention & Control,University of Virginia Health System,Charlottesville,Virginia.
authors.forename: Eve T
authors.initials: ET
authors.lastname: Giannetta
authors.affiliation: 1Division of Infectious Diseases & International Health,Department of Medicine,University of Virginia Health System,Charlottesville,Virginia.
authors.forename: Costi D
authors.initials: CD
authors.lastname: Sifri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001426:Bacterial Proteins / Q000096:biosynthesis*; D002353:Carrier State / Q000175:diagnosis* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D015169:Colony Count, Microbial; D024881:Drug Resistance, Bacterial; D004755:Enterobacteriaceae / Q000201:enzymology* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000175:diagnosis* / Q000382:microbiology / Q000517:prevention & control; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance / Q000379:methods*; D012007:Rectum / Q000382:microbiology; D012008:Recurrence; D012189:Retrospective Studies; D055815:Young Adult; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase