title: [Influence of tobacco smoking on the risk of developing asthma].
abstract: The aim of this general review is to investigate the influence of active and passive smoking on the development of asthma in children and adults. Passive smoking during and after pregnancy facilitates the onset of childhood asthma and wheezing. In particular, smoking during pregnancy is associated with the occurrence of wheezing prior to the age of 4 years. In contrast, the results of studies on the relationship between parental smoking in the post-natal period and the onset of asthma or wheezing are discordant. Exposure to passive smoking during childhood facilitates the occurrence of asthma in adulthood. In adults and adolescents, active smoking appears to be a factor favoring the development of asthma. On the other hand, non-smoking adult subjects without history of asthma exposed to passive smoking have a risk of asthma. The pathophysiological mechanisms by which tobacco smoke is the cause of asthma are still poorly known. Smoking cessation is an essential component in the management of asthmatic subjects who smoke, facilitating the control of the disease.
authors.affiliation: Unité de tabacologie, service de pneumologie, centre de lutte antituberculeuse (CLAT 86), CHU de Poitiers, 86000 Poitiers, France. Electronic address: m.underner@chu-poitiers.fr.
authors.forename: M
authors.initials: M
authors.lastname: Underner
authors.affiliation: Dispensaire Émile-Roux, centre de lutte antituberculeuse (CLAT 63), 63100 Clermont-Ferrand, France.
authors.forename: J
authors.initials: J
authors.lastname: Perriot
authors.affiliation: Service de pneumologie, CHR Metz-Thionville, 57038 Metz, France.
authors.forename: G
authors.initials: G
authors.lastname: Peiffer
authors.affiliation: Unité de tabacologie, service de pneumologie, centre de lutte antituberculeuse (CLAT 86), CHU de Poitiers, 86000 Poitiers, France.
authors.forename: J-C
authors.initials: JC
authors.lastname: Meurice
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D001249:Asthma / Q000453:epidemiology / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000453:epidemiology; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects* / Q000453:epidemiology; D014028:Tobacco Smoke Pollution / Q000009:adverse effects / Q000706:statistics & numerical data
chemical_list: D014028:Tobacco Smoke Pollution
keywords: Asthma; Asthme; Incidence; Passive smoking; Sifflements thoraciques; Smoking; Tabagisme; Tabagisme passif; Wheezing