title: Effects of atractylodis rhizoma pharmacopuncture on an acute gastric mucosal lesion induced by compound 48/80 in rats.
abstract: OBJECTIVE
  This study was designed to investigate the protective effects of Atractylodis Rhizoma pharmacopuncture (ARP) against acute gastric mucosal lesions induced by compound 48/80 in rats.
  
  
  METHODS
  The ARP was injected in Joksamni (ST36) and Jungwan (CV12) 1 hr before treatment with compound 48/80. The animals were sacrificed under anesthesia 3 hrs after treatment with compound 48/80. The stomachs were removed, and the amounts of gastric adherent mucus, gastric mucosal hexosamine, thiobarbituric acid reactive substances (TBARS), xanthine oxidase (XO), and superoxide dismutase (SOD) were measured. Also, histological examination were performed.
  
  
  RESULTS
  Gastric adherent mucus, gastric mucosal hexosamine and histological defects of gastric mucosa declined significantly after ARP treatment. Changes in gastric mucosal TBARS were also reduced by ARP treatment, but this result was not statistically significant. ARP treatment did not change the XO and the SOD activities.
  
  
  CONCLUSIONS
  ARP showed protective effects for acute gastric mucosal lesions induced by compound 48/80 in rats. These results suggest that ARP may have protective effects for gastritis.
authors.affiliation: Department of Acupuncture & Moxibustion, Daegu Haany University College of Oriental Medicine, Daegu, Korea.
authors.forename: Yun-Kyu
authors.initials: YK
authors.lastname: Lee
authors.affiliation: Department of Acupuncture & Moxibustion, Daegu Haany University College of Oriental Medicine, Daegu, Korea.
authors.forename: Jae-Soo
authors.initials: JS
authors.lastname: Kim
authors.affiliation: Department of Acupuncture & Moxibustion, Daegu Haany University College of Oriental Medicine, Daegu, Korea.
authors.forename: Seong-Chul
authors.initials: SC
authors.lastname: Lim
keywords: ARP (Atractylodis Rhizoma pharmacopuncture); Acupuncture; Acute gastric mucosal lesion; Compound 48/80; Joksamni (ST36); Jung-wan (CV12)