title: Satellite cells: regenerative mechanisms and applicability in muscular dystrophy.
abstract: The satellite cells are long regarded as heterogeneous cell population, which is intimately linked to the processes of muscular recovery. The heterogeneous cell population may be classified by specific markers. In spite of the significant amount of variation amongst the satellite cell populations, it seems that their activity is tightly bound to the paired box 7 transcription factor expression, which is, therefore, used as a canonical marker for these cells. Muscular dystrophic diseases, such as Duchenne muscular dystrophy, elicit severe tissue injuries leading those patients to display a very specific pattern of muscular recovery abnormalities. There have been works on the application of precursors cells as a therapeutic alternative for Duchenne muscular dystrophy and initial attempts have proven the cells inefficient; however later endeavours have proposed solutions for the experiments improving significantly the results. The presence of a range of satellite cells populations indicates the existence of specific cells with enhanced capability of muscular recovery in afflicted muscles.
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Gustavo Torres
authors.identifier: 0000-0002-7503-9423
authors.initials: GT
authors.lastname: de Souza
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Rafaella de Souza Salomão
authors.initials: Rde S
authors.lastname: Zanette
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Danielle Luciana Aurora Soares
authors.initials: DL
authors.lastname: do Amaral
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Francisco Carlos
authors.initials: FC
authors.lastname: da Guia
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Claudinéia Pereira
authors.initials: CP
authors.lastname: Maranduba
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Camila Maurmann
authors.initials: CM
authors.lastname: de Souza
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Ernesto da Silveira Goulart
authors.initials: Eda S
authors.lastname: Guimarães
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: João Vitor Paes
authors.initials: JV
authors.lastname: Rettore
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Natana Chaves
authors.initials: NC
authors.lastname: Rabelo
authors.affiliation: Department of Endodontology, Dentistry School, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Antônio Márcio Resende
authors.initials: AM
authors.lastname: do Carmo
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Fernando de Sá
authors.initials: Fde S
authors.lastname: Silva
authors.affiliation: Laboratory of Human Genetics and Cell Therapy, Biology Department, Biological Sciences Institute, Federal University of Juiz de Fora, 36036-900 Juiz de Fora, MG, Brazil.
authors.forename: Carlos Magno da Costa
authors.initials: CM
authors.lastname: Maranduba