title: Application of biomarkers in Epaulet grouper (Epinephelus stoliczkae) to assess chromium pollution in the Chabahar Bay and Gulf of Oman.
abstract: In the present study plasma levels of erythropoietin (EPO) hormone and kidney histological changes were assessed as biomarkers to evaluate the chromium pollution in Epaulet grouper (Epinephelus stoliczkae) obtained from different areas in Chabahar Bay and Gulf of Oman. Chemical analyses included the evaluation of chromium in the fish kidney tissue and sediment. The highest and lowest concentrations of chromium were measured in the kidney of fish and sediment collected from Konarak (47.53±1.23 and 110±1.4 μg g(-1)) and the mouth of Chabahar Bay (3.43±1.31 and 13.5±3.23 μg g(-1)), respectively. There was significant difference (P<0.05) of EPO plasma levels between Konarak, Beris and Ramin stations with the mouth of Chabahar Bay as the cleanest station. Reduction of Bowman's space, occlusion of the tubule lumen, leukocytes infiltration, melanomacrophage centers aggregation, nuclear vacuolation, nuclei hypertrophy of tubule cells, necrosis of the tubules, lifting of the tubular basement membrane and dilatation of glomerular capillaries were the most alterations observed in the kidney. The HAI values of Epaulet grouper from Konarak, Beris and Ramin stations were significantly higher than other stations (P<0.05). It was concluded that selected biomarkers as a first investigation could be useful tools to environmental biomonitoring programs.
authors.affiliation: Marine Biology Department, Marine Science Faculty, Chabahar Maritime University, Chabahar, Iran. Electronic address: parvin.sadeghi@gmail.com.
authors.forename: Parvin
authors.initials: P
authors.lastname: Sadeghi
authors.affiliation: Department of Laboratory Medicine, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Faranak
authors.initials: F
authors.lastname: Kazerouni
authors.affiliation: Marine Biology Department, Marine and Oceanic Science Faculty, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
authors.forename: Ahmad
authors.initials: A
authors.lastname: Savari
authors.affiliation: Marine Biology Department, Marine and Oceanic Science Faculty, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
authors.forename: Abdolali
authors.initials: A
authors.lastname: Movahedinia
authors.affiliation: Marine Biology Department, Marine and Oceanic Science Faculty, Khorramshahr University of Marine Science and Technology, Khorramshahr, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Safahieh
authors.affiliation: Iranian Fisheries Research Organization, Tehran, Iran.
authors.forename: Daniel
authors.initials: D
authors.lastname: Ajdari
mesh_terms: D000818:Animals; D001492:Bass / Q000378:metabolism*; D061006:Bays / Q000737:chemistry; D015415:Biomarkers / Q000378:metabolism; D002857:Chromium / Q000378:metabolism*; D004784:Environmental Monitoring / Q000379:methods*; D009850:Oman; D014874:Water Pollutants, Chemical / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D014874:Water Pollutants, Chemical; D002857:Chromium
keywords: Biomarker; Chromium; Epinephelus stoliczkae; Erythropoietin; Kidney