title: Intramolecular decarboxylative coupling as the key step in copper-catalyzed domino reaction: facile access to 2-(1,3,4-oxadiazol-2-yl)aniline derivatives.
abstract: A copper-catalyzed domino protocol for the synthesis of 2-(1,3,4-oxadiazol-2-yl)aniline derivatives has been developed from simple and available isatins and hydrazides. This domino process integrated consecutive condensation, base-promoted ring-opening and the key copper-catalyzed decarboxylative coupling for intramolecular C-O bond formation.
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. chwuax@mail.ccnu.edu.cn.
authors.forename: Cheng
authors.initials: C
authors.lastname: Xu
authors.forename: Feng-Cheng
authors.initials: FC
authors.lastname: Jia
authors.forename: Qun
authors.initials: Q
authors.lastname: Cai
authors.forename: Deng-Kui
authors.initials: DK
authors.lastname: Li
authors.forename: Zhi-Wen
authors.initials: ZW
authors.lastname: Zhou
authors.forename: An-Xin
authors.initials: AX
authors.lastname: Wu