title: Sustained effects of a protein 'preload' on glycaemia and gastric emptying over 4 weeks in patients with type 2 diabetes: A randomized clinical trial.
abstract: We have shown that the capacity of 25g whey preloads to slow gastric emptying and reduce postprandial glycaemia persists after 4 weeks regular exposure in patients with diet-controlled type 2 diabetes. This dietary strategy therefore appears feasible for larger clinical trials to evaluate beneficial effects on long-term glycaemic control. Registered with the Australian New Zealand Clinical Trials Registry: ACTRN12614000831684.
authors.affiliation: Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia.
authors.forename: Jing
authors.initials: J
authors.lastname: Ma
authors.affiliation: CSIRO Human Nutrition, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia; Endocrine & Metabolic Unit, Royal Adelaide Hospital, Adelaide, Australia.
authors.forename: David R
authors.initials: DR
authors.lastname: Jesudason
authors.affiliation: Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia; School of Pharmacy and Medical Sciences, University of South AustraliaAdelaide, Australia.
authors.forename: Julie E
authors.initials: JE
authors.lastname: Stevens
authors.affiliation: Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia; School of Pharmacy and Medical Sciences, University of South AustraliaAdelaide, Australia.
authors.forename: Jennifer B
authors.initials: JB
authors.lastname: Keogh
authors.affiliation: Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia.
authors.forename: Karen L
authors.initials: KL
authors.lastname: Jones
authors.affiliation: Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia; School of Pharmacy and Medical Sciences, University of South AustraliaAdelaide, Australia.
authors.forename: Peter M
authors.initials: PM
authors.lastname: Clifton
authors.affiliation: Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia; Endocrine & Metabolic Unit, Royal Adelaide Hospital, Adelaide, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Horowitz
authors.affiliation: Discipline of Medicine, University of Adelaide, Royal Adelaide Hospital, Adelaide, Australia; Centre of Research Excellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia. Electronic address: chris.rayner@adelaide.edu.au.
authors.forename: Christopher K
authors.initials: CK
authors.lastname: Rayner
mesh_terms: D001315:Australia; D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D018592:Cross-Over Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology; D004044:Dietary Proteins / Q000494:pharmacology* / Q000627:therapeutic use*; D005260:Female; D005746:Gastric Emptying / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000178:diet therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D019518:Postprandial Period / Q000502:physiology; D016037:Single-Blind Method; D013997:Time Factors; D016896:Treatment Outcome; D000067816:Whey Proteins / Q000494:pharmacology* / Q000627:therapeutic use*
chemical_list: D001786:Blood Glucose; D004044:Dietary Proteins; D000067816:Whey Proteins
keywords: Fructosamine; Glycated haemoglobin; Scintigraphy; Whey