title: Mortality risk for women on chronic hemodialysis differs by age.
abstract: BACKGROUND
  Previous reports have demonstrated similar survival for men and women on hemodialysis, despite women's increased survival in the general population.
  
  
  OBJECTIVE
  To examine the effect of age on mortality in women undergoing chronic hemodialysis.
  
  
  METHODS
  A retrospective cohort study using an administrative data registry, the Canadian Organ Replacement Registry (CORR) from Jan. 2001 and Dec. 2009.
  
  
  METHODS
  Canada.
  
  
  METHODS
  28,971 (Women 11,792 (40.7%), Men 17,179 (59.3%)) incident chronic hemodialysis patients who survived greater than 90 days on dialysis.
  
  
  METHODS
  All-cause mortality.
  
  
  METHODS
  Cox proportional hazards and competing risks models were employed to determine the independent association between sex, age and likelihood of all-cause mortality with renal transplantation as the competing outcome.
  
  
  RESULTS
  During the study period, 6060 (51.4%) of women and 8650 (50.4%) of men initiating dialysis died. Younger women experienced higher mortality (Age < 45: Women 22.5%, Men 18.2%, hazard ratio (HR) 1.31 (1.12-1.52)) whereas elderly women experience lower mortality (Age 75-85: Women 65%, Men 67.3%, HR 0.94 95% CI 0.88-0.99, Age > 85: Women 66%, Men 70.2%, HR 0.83 95% CI 0.71-0.97) compared to men. This relationship persisted after accounting for the competing risk of transplantation.
  
  
  CONCLUSIONS
  The cause of death was unknown.
  
  
  CONCLUSIONS
  Women's survival on chronic hemodialysis varies by age compared to men with a significantly higher mortality in women younger than 45 years old and lower mortality in woman older than 75 years of age.
authors.affiliation: Ottawa Hospital Research Institute, The Ottawa Hospital, Civic campus, 2-014 Administrative Services Building, 1053 Carling Avenue, Box 693, Ottawa, Ontario K1Y 4E9 Canada.
authors.forename: Manish M
authors.initials: MM
authors.lastname: Sood
authors.affiliation: Department of Medicine, Section of Nephrology, Seven Oaks Hospital, University of Manitoba, 2300 McPhillips Street, Winnipeg, R2V 3M3 Canada.
authors.forename: Claudio
authors.initials: C
authors.lastname: Rigatto
authors.affiliation: Department of Medicine, Section of Nephrology, Seven Oaks Hospital, University of Manitoba, 2300 McPhillips Street, Winnipeg, R2V 3M3 Canada.
authors.forename: Paul
authors.initials: P
authors.lastname: Komenda
authors.affiliation: Department of Medicine, Health Sciences Centre, University of Manitoba, 820 Sherbrook street, Winnipeg, Manitoba R3A 1R9 Canada.
authors.forename: Julie
authors.initials: J
authors.lastname: Mojica
authors.affiliation: Department of Medicine, Section of Nephrology, Seven Oaks Hospital, University of Manitoba, 2300 McPhillips Street, Winnipeg, R2V 3M3 Canada.
authors.forename: Navdeep
authors.initials: N
authors.lastname: Tangri