title: Cerebrospinal fluid involvement in acute promyelocytic leukaemia at presentation.
abstract: In acute promyelocytic leukaemia (APL), extramedullary disease (EMD) is rare but can occur in those who relapse following therapy. Although the most common site of EMD in APL is central nervous system (CNS) and skin, CNS involvement in recently diagnosed patients with APL is very rare and rarely described. We report cerebrospinal fluid involvement in a case of APL, on day 3 of induction therapy.
authors.affiliation: Department of Pathology, School of Medical Sciences and Research, Greater Noida, Uttar Pradesh, India.
authors.forename: Jyoti
authors.initials: J
authors.lastname: Mishra
authors.affiliation: Department of General Pathology, Christian Medical College, Vellore, Tamil Nadu, India.
authors.forename: Mayank
authors.initials: M
authors.lastname: Gupta
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D042381:Granulocyte Precursor Cells / Q000473:pathology; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000175:diagnosis* / Q000188:drug therapy; D009195:Peroxidase / Q000032:analysis
chemical_list: D009195:Peroxidase