title: Chiral pyrrolidines and piperidines from enantioselective rhodium-catalyzed cascade arylative cyclization.
abstract: A new rhodium-catalyzed asymmetric arylative cyclization of nitrogen-tethered alkyne-enoate with arylboronic acids is described. In this process two new carbon-carbon bonds and one stereocenter are formed, providing access to pyrrolidines and piperidines with good enantioselectivities by to the use of C1-symmetric chiral monosubstituted diene ligands.
authors.affiliation: †PSL Research University, Chimie ParisTech - CNRS, Institut de Recherche de Chimie Paris, 11 rue Pierre et Marie Curie, 75005, Paris, France.
authors.forename: Fabien
authors.initials: F
authors.lastname: Serpier
authors.affiliation: †PSL Research University, Chimie ParisTech - CNRS, Institut de Recherche de Chimie Paris, 11 rue Pierre et Marie Curie, 75005, Paris, France.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Flamme
authors.affiliation: ‡Diverchim, ZAC du Moulin, 6 rue du Noyer, 95700 Roissy-en-France, France.
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Brayer
authors.affiliation: ‡Diverchim, ZAC du Moulin, 6 rue du Noyer, 95700 Roissy-en-France, France.
authors.forename: Benoît
authors.initials: B
authors.lastname: Folléas
authors.affiliation: †PSL Research University, Chimie ParisTech - CNRS, Institut de Recherche de Chimie Paris, 11 rue Pierre et Marie Curie, 75005, Paris, France.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Darses