title: Metastasectomy for stage IV melanoma.
abstract: Metastatic melanoma has an unpredictable natural history but a predictably high mortality. Despite recent advances in systemic therapy, many patients do not respond, or develop resistance to drug therapy. Surgery has consistently shown good outcomes in appropriately selected patients. It is likely to be even more successful in the era of more effective medical treatment. Surgery should remain a strongly considered option for metastatic melanoma.
authors.affiliation: Melanoma Research Program, John Wayne Cancer Institute, Providence St. John's Hospital, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA.
authors.forename: Gary B
authors.initials: GB
authors.lastname: Deutsch
authors.affiliation: Melanoma Research Program, John Wayne Cancer Institute, Providence St. John's Hospital, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA.
authors.forename: Daniel D
authors.initials: DD
authors.lastname: Kirchoff
authors.affiliation: Melanoma Research Program, John Wayne Cancer Institute, Providence St. John's Hospital, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA. Electronic address: mark.faries@jwci.org.
authors.forename: Mark B
authors.initials: MB
authors.lastname: Faries
mesh_terms: D006801:Humans; D008545:Melanoma / Q000473:pathology* / Q000601:surgery* / Q000628:therapy; D059146:Metastasectomy; D009367:Neoplasm Staging; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery* / Q000628:therapy; D016019:Survival Analysis
keywords: Metastasectomy; Metastatic melanoma; Oligometastases; Stage IV melanoma; Surgery