title: An entry to vinylcyclopropane through palladium-catalyzed intramolecular cyclopropanation of alkenes with unstabilized allylic tosylhydrazones.
abstract: A diastereoselective Pd-catalyzed intramolecular cyclopropanation of alkenes with unstabilized allylic tosylhydrazones was developed. This methodology provides an efficient entry toward synthesis of the bicyclo[3.1.0] hexane system with an exo-double bond, and sets the basis for future elaboration of more complex polycyclic motifs.
authors.affiliation: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China. chembliu@scu.edu.cn.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.forename: Jinpeng
authors.initials: J
authors.lastname: Li
authors.forename: Biao
authors.initials: B
authors.lastname: Du
authors.forename: Changchun
authors.initials: C
authors.lastname: Yuan
authors.forename: Bo
authors.initials: B
authors.lastname: Liu
authors.forename: Song
authors.initials: S
authors.lastname: Qin
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry*; D006835:Hydrazones / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D013237:Stereoisomerism; D014105:Tosyl Compounds / Q000737:chemistry*
chemical_list: D000475:Alkenes; D001643:Bridged Bicyclo Compounds; D003517:Cyclopentanes; D006835:Hydrazones; D009942:Organometallic Compounds; D014105:Tosyl Compounds; C046059:bicyclo(3.1.0)hexane; D010165:Palladium