title: Norepinephrinergic and nitroxidergic neurons of vasomotor nuclei in hypertensive rats.
abstract: The distributions of norepinephrinergic and nitroxidergic neurons in solitary tract nucleus, locus coeruleus, and in the small-celled and gigantocellular reticular nuclei were examined in sham-operated and experimental Wistar rats with induced renovascular hypertension. In control rats, the greatest population of norepinephrinergic cells was revealed in the projections of locus coeruleus and reticular gigantocellular nuclei, while the larger number of nitroxidergic neurons were observed in the solitary tract and the small-celled nuclei. During renovascular hypertension, the earliest and the most pronounced changes in luminescence intensity and the number of nitroxidergic neurons were observed in the solitary tract nucleus, while the changes in locus coeruleus were minimal. The significant changes in similar parameters of norepinephrinergic neurons were documented only in reticular gigantocellular nucleus and locus coeruleus, but they were delayed and less pronounced in comparison with the changes of nitroxidergic neurons.
authors.affiliation: Department of Human Anatomy, Pacific State Medical University, Ministry of Health of the Russian Federation, Vladivostok, Russia, chertokv@mail.ru.
authors.forename: V M
authors.initials: VM
authors.lastname: Chertok
authors.forename: A E
authors.initials: AE
authors.lastname: Kotsyuba
mesh_terms: D000818:Animals; D006973:Hypertension / Q000378:metabolism*; D008297:Male; D009474:Neurons / Q000378:metabolism*; D026602:Nitrergic Neurons / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D011941:Receptors, Adrenergic / Q000378:metabolism*
chemical_list: D011941:Receptors, Adrenergic