title: Caps off to poxviruses.
abstract: In this issue of Cell Host & Microbe, Liu et al. (2015) and Burgess and Mohr (2015) describe how two poxvirus mRNA decapping enzymes hijack a host 5'-to-3'-exoribonuclease to evade antiviral innate immunity by limiting accumulation of double-stranded RNA.
authors.affiliation: Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA. Electronic address: silverr@ccf.org.
authors.forename: Robert H
authors.initials: RH
authors.lastname: Silverman
mesh_terms: D000818:Animals; D004722:Endoribonucleases / Q000378:metabolism*; D005095:Exoribonucleases / Q000378:metabolism*; D054884:Host-Pathogen Interactions; D006801:Humans; D007113:Immunity, Innate; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D012330:RNA, Double-Stranded / Q000378:metabolism*; D014616:Vaccinia virus / Q000201:enzymology* / Q000276:immunology* / Q000502:physiology*; D014779:Virus Replication
chemical_list: D008869:Microtubule-Associated Proteins; D012330:RNA, Double-Stranded; D004722:Endoribonucleases; D005095:Exoribonucleases