title: Contrast-enhanced ultrasonography to assess blood perfusion of skeletal muscles in normal dogs.
abstract: This study evaluated perfusion of skeletal muscle using contrast enhanced ultrasonography in humerus, radius, femur and tibia in normal dogs. Contrast enhanced ultrasonography for each region was performed after injecting 0.5 mL and 1 mL of contrast medium (SonoVue) in every dog. Blood perfusion was assessed quantitatively by measuring the peak intensity, time to the peak intensity and area under the curve from the time-intensity curve. Vascularization in skeletal muscle was qualitatively graded with a score of 0-3 according to the number of vascular signals. A parabolic shape of time-intensity curve was observed from muscles in normal dogs, and time to the peak intensity, the peak intensity and area under the curve of each muscle were not significantly different according to the appendicular regions examined and the dosage of contrast agent administered. This study reports that feasibility of contrast enhanced ultrasonography for assessment of the muscular perfusion in canine appendicular regions.
authors.affiliation: Department of Veterinary Medical Imaging, College of Veterinary Medicine, Chonnam National University, Gwangju 500-757, South Korea.
authors.forename: Juyeon
authors.initials: J
authors.lastname: Oh
authors.forename: Sunghoon
authors.initials: S
authors.lastname: Jeon
authors.forename: Jihye
authors.initials: J
authors.lastname: Choi
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000378:metabolism; D004285:Dogs / Q000033:anatomy & histology; D008297:Male; D018482:Muscle, Skeletal / Q000098:blood supply* / Q000000981:diagnostic imaging; D010743:Phospholipids / Q000378:metabolism; D012039:Regional Blood Flow / Q000502:physiology; D013459:Sulfur Hexafluoride / Q000378:metabolism; D014463:Ultrasonography
chemical_list: D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D013459:Sulfur Hexafluoride