title: Generation of bis-acyl ketals from esters and benzyl amines under oxidative conditions.
abstract: Treatment of benzylamines with esters at an elevated temperature are expected to give amides. However, in the presence of TBAI/TBHP, esters possessing a methylene carbon α-to oxygen with benzylamines provide bis-esters rather than the expected amides. Benzylamines under oxidative conditions generate less nucleophilic carboxylates, which couples at the sp(3) C-H bonds of esters and cyclic ethers to give bis-acyl ketals and α-acyloxy ethers, respectively.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
authors.forename: Ganesh
authors.initials: G
authors.lastname: Majji
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
authors.forename: Suresh
authors.initials: S
authors.lastname: Rajamanickam
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
authors.forename: Nilufa
authors.initials: N
authors.lastname: Khatun
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
authors.forename: Sourav Kumar
authors.initials: SK
authors.lastname: Santra
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
authors.forename: Bhisma K
authors.initials: BK
authors.lastname: Patel