title: Blastic plasmacytoid dendritic cell neoplasm of the skin associated with myelodysplastic syndrome.
abstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a recently described, rare hematologic malignancy with prominent skin involvement. The prognosis of this disease is poor in most cases, with rapid progression despite chemotherapy administration. The first reported case of this disease was in 1994, and less than 200 cases worldwide have been described in the literature to date. Moreover coexistence of BPDCN and MDS is extremely rare. In this study, we describe a typical patient with BPDCN in China who presented with cutaneous involvement as the first manifestation associated with MDS; a brief review of literature is also given.
authors.forename: Qing-Tao
authors.initials: QT
authors.lastname: Kong
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Jinling Hospital, Nanjing University.
authors.forename: Hong
authors.initials: H
authors.lastname: Sang
authors.forename: Jun
authors.initials: J
authors.lastname: Chen
authors.forename: Wenliang
authors.initials: W
authors.lastname: Yan
authors.forename: Wenxing
authors.initials: W
authors.lastname: Hu
authors.forename: Dequan
authors.initials: D
authors.lastname: Deng
authors.forename: Qimei
authors.initials: Q
authors.lastname: Xie
mesh_terms: D015703:Antigens, CD / Q000032:analysis; D003713:Dendritic Cells / Q000473:pathology; D019337:Hematologic Neoplasms / Q000150:complications* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000473:pathology; D012878:Skin Neoplasms / Q000150:complications* / Q000276:immunology / Q000473:pathology
chemical_list: D015703:Antigens, CD