title: Plasma vitamin D levels of patients with allergic rhino-conjunctivitis with positive skin prick test.
abstract: BACKGROUND
  Allergic rhino-conjunctivitis (ARC) and allergic rhinitis are inflammatory diseases that develop through immunoglobulin E in the rhino-ocular mucosa due to allergy. The main symptoms are runny nose, nasal congestion, sneezing, itchy nose, and conjunctivitis.
  
  
  OBJECTIVE
  This study was designed to evaluate plasma 25-hydroxyvitamin D levels in patients with ARC.
  
  
  METHODS
  This study was planned as a prospective and cross sectional study. This study was performed in a tertiary referral center.
  
  
  METHODS
  This observational study involved 42 patients with ARC and 35 consecutive, age- and sex-matched healthy subjects. Patients in both groups underwent skin-prick test. Plasma 25-hydroxyvitamin D levels of all subjects were quantified with electrochemiluminescence technique. Results were compared between the groups and p < 0.05 was considered as statistically significant.
  
  
  RESULTS
  Group one included 42 ARC patients (15 male, 27 female, ages between 12 and 43, average age 25.7 ± 8.6); group two included 35 healthy people (15 male, 20 female, ages between 12 and 44, average age 26.9 ± 9.1). Plasma 25-hydroxyvitamin D levels of the subjects with ARC group (7.33 ± 3.61 ng/mL, standard error mean: 0.55, range 3.17-13.68 ng/mL) were significantly lower than the control group (13.37 ± 5.42 ng/mL, standard error mean: 0.91, range 6.84-25.92 ng/mL) (p = 0.010, Independent-Samples test).
  
  
  CONCLUSIONS
  We found lower plasma vitamin D levels in patients with ARC when compared with the control group.
authors.affiliation: Konya Hospital, Otorhinolaryngology Clinic, Konya, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Yenigun
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Dadaci
authors.forename: Mufide
authors.initials: M
authors.lastname: Oncel
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003233:Conjunctivitis, Allergic / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D011446:Prospective Studies; D065631:Rhinitis, Allergic / Q000175:diagnosis*; D012882:Skin Tests; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D055815:Young Adult
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D