title: Metachronous metastasis from the right colon adenocarcinoma to the vulva: an unusual report and literature review.
abstract: A 67-year-old woman who was presented to the gynecologist with a two-month history of heavy vaginal bleeding, after an excisional biopsy of vulvar mass, was diagnosed with the right colon adenocarcinoma metachronous metastasis to the vulva. Pathological examination preliminarily revealed by primary adenosquamous carcinoma of vulva. The original submitting pathologist and gynecologist were contacted to obtain the pathological and clinical information whenever possible, combining with a history of the right colon cancer, subsequently, which confirmed the diagnosis of vulvar metastatic adenocarcinoma. Distinguishing metastatic carcinoma from primary vulvar adenocarcinoma is crucial, since these carcinomas are different. Herein reports the second case of the right colon carcinoma presenting as a vulvar metastasis. This report also shows the differentiation, diagnosis and treatment of metastatic colon carcinoma and its metastatic route.
authors.affiliation: Department of Oncology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University Chengdu, China.
authors.forename: Kexing
authors.initials: K
authors.lastname: Ren
authors.affiliation: Department of Oncology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University Chengdu, China.
authors.forename: Xuelei
authors.initials: X
authors.lastname: Ma
authors.affiliation: Department of Oncology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University Chengdu, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Wang
authors.affiliation: Department of Oncology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University Chengdu, China.
authors.forename: Fuchun
authors.initials: F
authors.lastname: Guo
authors.affiliation: Department of Ultrasonography, West China Second Hospital, Sichuan University Chengdu, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: Department of Oncology and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University Chengdu, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary*; D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D014846:Vulvar Neoplasms / Q000556:secondary*
keywords: Colon adenocarcinoma; differentiation; metachronous metastasis; metastatic route; treatment; vulvar adenocarcinoma