title: Metabolic status and personality affect the prognosis of patients with continuous ambulatory peritoneal dialysis.
abstract: Continuous ambulatory peritoneal dialysis (CAPD) is recognized as an effective and economical therapy for end-stage renal disease (ESRD). However, the drop-out and mortality rates of this treatment remain high. The aim of the present study was to investigate the potential effects of metabolic status and personality on the prognosis of ESRD patients receiving CAPD. A total of 835 patients (455 men and 380 women) were enrolled in the cross-sectional survey. Analysis of variance and Spearman correlations were used to analyze variables in two groups of ESRD patients: group L (dialysis duration < 3 years) and group H (dialysis duration ≥ 3 years). The variables included gender, age, duration of dialysis, primary diseases, blood pressure, body mass index (BMI), hemoglobin (Hb), serum albumin, Subjective Global Assessment (SGA), blood lipids, fasting blood glucose, renal function, immunoreactive parathyroid hormone (iPTH), serum phosphorus and calcium, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Kt/V, and Life Orientation Test-Revised (LOT-R) scores. Levels of DBP, BUN, glucose, CRP, SBP, SGA, TG, LDL, creatinine, iPTH, ESR, and LOT-R scores were significantly higher in group H than in Group L, whereas Hb and Kt/V were significantly lower in group H. The dialysis duration was positively correlated with the blood pressure, SGA scores, TG, LDL, PTH, CRP, and LOT-R scores, but negatively correlated with Kt/V. Our results suggest that hypertension, anemia, hypoproteinemia, SGA, TG, LDL, iPTH, CRP, Kt/V, and personalities are potentially important factors affecting the prognosis of ERSD patients with CAPD.
authors.affiliation: Department of Nephropath, The Third Xiangya Hospital of Central South University Changsha 410000, Hunan, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Nephropath, The Third Xiangya Hospital of Central South University Changsha 410000, Hunan, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Nephropath, The Third Xiangya Hospital of Central South University Changsha 410000, Hunan, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Zhang
authors.affiliation: Department of Nephropath, The Third Xiangya Hospital of Central South University Changsha 410000, Hunan, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Nephropath, Shaoyang Central Hospital Shaoyang 422000, Hunan, China.
authors.forename: Liuchan
authors.initials: L
authors.lastname: Zhou
authors.affiliation: Department of Nephropath, The First Hospital in Chenzhou Chenzhou 423000, Hunan, China.
authors.forename: Xiangping
authors.initials: X
authors.lastname: Liao
authors.affiliation: Department of Nephropath, Xiangtan Central Hospital Xiangtan 411100, Hunan, China.
authors.forename: Jianzhao
authors.initials: J
authors.lastname: Cheng
authors.affiliation: Department of Nephropath, The First Hospital in Yiyang Yiyang 413000, Hunan, China.
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Deng
authors.affiliation: Department of Nephropath, The First Hospital in Huaihua Huaihua 418000, Hunan, China.
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Xia
keywords: Continuous ambulatory peritoneal dialysis; dialysis adequacy; inflammation; nutrition; personality