title: The Effect of Peripapillary Detachment on Retinal Nerve Fiber Layer Measurement by Spectral Domain Optical Coherence Tomography in High Myopia.
abstract: OBJECTIVE
  The aim of this study was to investigate the repercussions of peripapillary detachment on retinal nerve fiber layer (RNFL) measurements in patients with highly myopic eyes.
  
  
  METHODS
  A total of 244 highly myopic eyes underwent a complete ophthalmologic examination that included optical coherence tomography (OCT) to analyze the peripapillary retina and RNFL thickness. Based on the OCT findings, patients were grouped as follows: group A: eyes with a peripapillary intrachoroidal cavitation (PIC); group B: eyes with a peripapillary neurosensory retinal detachment (PNRD), and group C: eyes without a peripapillary detachment.
  
  
  RESULTS
  The OCT scans identified a peripapillary detachment in 42 eyes (17.21%). Out of these 42 eyes, 22 showed PIC (52.38%; group A) and 20 had a PNRD (47.62%; group B). The average overall RNFL thickness in groups A, B and C was 74.11 ± 10.88, 88.26 ± 25.72 and 72.75 ± 16.24 μm, respectively (ANOVA test, p = 0.00).
  
  
  CONCLUSIONS
  Eyes with a PNRD had a significantly greater average RFNL thickness than those without peripapillary detachment in pathologic myopia due to a misidentification of the outer profile of the RFNL. This fact makes the interpretation of RNFL thickness in highly myopic eyes more challenging.
authors.affiliation: Department of Ophthalmology, Hospital Universitario Virgen de la Victoria, Málaga, Spain.
authors.forename: Radua
authors.initials: R
authors.lastname: Kamal Salah
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Morillo-Sánchez
authors.forename: Antonio
authors.initials: A
authors.lastname: García-Ben
authors.forename: Francisca
authors.initials: F
authors.lastname: Rius-Diaz
authors.forename: Ángel
authors.initials: Á
authors.lastname: Cilveti-Puche
authors.forename: Laura
authors.initials: L
authors.lastname: Figueroa-Ortiz
authors.forename: Jose Manuel
authors.initials: JM
authors.lastname: García-Campos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000150:complications*; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology; D012163:Retinal Detachment / Q000175:diagnosis*; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology