title: Refractory cardiogenic shock in a patient with β-thalassemia major requiring mechanical circulatory support: Case report and literature review.
abstract: Iron overload cardiomyopathy secondary to β-thalassemia major is a potentially reversible condition managed with chelation and medical hemodynamic support, as bridge-to-recovery or transplant. We describe our experience, and challenges faced, in a pediatric patient with iron overload cardiomyopathy secondary to β-thalassemia major, requiring biventricular MCS.
authors.affiliation: Division of Cardiac Surgery, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: David
authors.initials: D
authors.lastname: Horne
authors.forename: Jennifer
authors.initials: J
authors.lastname: Conway
authors.forename: Paul F
authors.initials: PF
authors.lastname: Kantor
authors.forename: Mohammed M
authors.initials: MM
authors.lastname: AlAklabi
authors.forename: Vijay
authors.initials: V
authors.lastname: Anand
authors.forename: Aisha
authors.initials: A
authors.lastname: Bruce
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Garcia Guerra
authors.forename: Ivan M
authors.initials: IM
authors.lastname: Rebeyka
authors.forename: David B
authors.initials: DB
authors.lastname: Ross
authors.forename: Holger
authors.initials: H
authors.lastname: Buchholz
mesh_terms: D000293:Adolescent; D009202:Cardiomyopathies / Q000209:etiology / Q000628:therapy; D002614:Chelating Agents / Q000627:therapeutic use; D005260:Female; D016027:Heart Transplantation; D006353:Heart-Assist Devices / Q000706:statistics & numerical data; D006439:Hemodynamics; D006801:Humans; D019190:Iron Overload / Q000209:etiology / Q000628:therapy; D013902:Radiography, Thoracic; D012770:Shock, Cardiogenic / Q000209:etiology* / Q000628:therapy; D017086:beta-Thalassemia / Q000150:complications / Q000628:therapy*
chemical_list: D002614:Chelating Agents
keywords: cardiomyopathy; paediatrics; surgery; transition