title: Risk factor panels associated with hypertension in obstructive sleep apnea patients with different body mass indexes.
abstract: Although hypertension (HTN), obstructive sleep apnea (OSA), and obesity frequently co-occur, the precise role of obesity in this interrelationship is not completely understood. A total of 727 OSA patients were assigned to body mass index (BMI) <25 (27.6%; n = 201), 25≤ BMI <29.99 (53.4%; n = 388), and BMI ≥30 (19%; n = 138). HTN risk factors in each group were evaluated. A total of 244 (33.6%) patients exhibited co-morbid HTN, of whom 20.5% (50/244), 52.9% (129/244), and 26.6% (65/244) were distributed between the BMI <25, 25≤ BMI <29.99, and BMI ≥30 groups, respectively. Multiple logistic regression indicated that age, male gender, triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and apnea-hypopnea index (AHI) scores were HTN risk factors for the BMI<25 group. In the 25≤ BMI <29.99 group, risk factors were age, BMI, diabetes, and AHI. Finally, in the BMI ≥30 group, risk factors were age, diabetes, TG, LDL-C and AHI. These results demonstrate that different risk factor panels were associated with HTN in OSA patients with different BMIs.
authors.affiliation: Department of Cardiology, the Center Hospital of Minhang District, Shanghai, China. Electronic address: 18918169120@163.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Hu
authors.affiliation: Department of Cardiology, the Center Hospital of Minhang District, Shanghai, China.
authors.forename: Xian
authors.initials: X
authors.lastname: Jin
authors.affiliation: Department of Cardiology, the Center Hospital of Minhang District, Shanghai, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Gu
authors.affiliation: Department of Cardiology, the Center Hospital of Minhang District, Shanghai, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, the Center Hospital of Minhang District, Shanghai, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Yu
authors.affiliation: Department of Cardiology, the Center Hospital of Minhang District, Shanghai, China.
authors.forename: Guizhi
authors.initials: G
authors.lastname: Yin
authors.affiliation: Department of Cardiology, the Center Hospital of Minhang District, Shanghai, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Department of Cardiology, the Center Hospital of Minhang District, Shanghai, China.
authors.forename: Hongbing
authors.initials: H
authors.lastname: Xiao
authors.affiliation: Department of Cardiology, the Center Hospital of Minhang District, Shanghai, China.
authors.forename: Yueguang
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Cardiology, the Center Hospital of Minhang District, Shanghai, China.
authors.forename: Dadong
authors.initials: D
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000886:Anthropometry; D015992:Body Mass Index; D003710:Demography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications*
chemical_list: D008055:Lipids
keywords: Body mass indexes; hypertension; obstructive sleep apnea; risk factor panels