title: Quantitative microleakage analysis of root canal filling materials in single-rooted canals.
abstract: The purpose of this study was to analyze the sealing ability of different root canal filling materials over a 6-week period using a glucose penetration model. Forty-six recently extracted human premolars were used in this study. The root canals were enlarged to 40/0.06. Prepared canals were randomly assigned into four groups (n = 10) as follows: Group 1, Gutta-Percha (GP)/AH Plus with cold lateral compaction; Group 2, GP/AH Plus with continuous wave compaction; Group 3, RealSeal SE obturation system; and Group 4, OrthoMTA. The remaining specimens were used as positive and negative controls, and all specimens underwent thermocycling (10,000; 5-55 °C). The sealing ability of all samples was evaluated at 24 h, 1, 2, 4, and 6 weeks using a quantitative glucose leakage model, and scanning electron microscope (SEM) images were taken. A mixed effect analysis using R statistical language was performed. Groups 1, 2, and 4 showed low leakage levels during experimental periods. Group 3 showed low leakage levels for the first 2 weeks; however, the leakage level was significantly increased after 2 weeks compared to negative control group (p < 0.05). In the SEM results, Group 3 showed imperfect dentin bonding, whereas Group 4 showed calcium silicate hydrate short tags, which are formed at the access of the dentin tubules. GP/AH Plus and OrthoMTA showed less microleakage than RealSeal SE obturation system when used as root canal filling materials. Traditional GP/AH Plus sealer and the newly developed OrthoMTA are more appropriate for ideal sealing of the root canals.
authors.affiliation: Department of Conservative Dentistry, Seoul St. Mary's Dental Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: Sin-Young
authors.initials: SY
authors.lastname: Kim
authors.affiliation: Department of Conservative Dentistry, Seoul St. Mary's Dental Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: Kyung-Jae
authors.initials: KJ
authors.lastname: Kim
authors.affiliation: Department of Dentistry, Inje University Seoul Paik Hospital, Seoul, Korea.
authors.forename: Young-Ah
authors.initials: YA
authors.lastname: Yi
authors.affiliation: Department of Conservative Dentistry, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.
authors.forename: Deog-Gyu
authors.initials: DG
authors.lastname: Seo
keywords: AH Plus; Gutta-percha; OrthoMTA; RealSeal SE; microleakage