title: Evaluation of the potassium adsorption capacity of a potassium adsorption filter during rapid blood transfusion.
abstract: The concentration of extracellular potassium in red blood cell concentrates (RCCs) increases during storage, leading to risk of hyperkalemia. A potassium adsorption filter (PAF) can eliminate the potassium at normal blood transfusion. This study aimed to investigate the potassium adsorption capacity of a PAF during rapid blood transfusion. We tested several different potassium concentrations under a rapid transfusion condition using a pressure bag. The adsorption rates of the 70-mEq/l model were 76·8%. The PAF showed good potassium adsorption capacity, suggesting that this filter may provide a convenient method to prevent hyperkalemia during rapid blood transfusion.
authors.affiliation: Department of Clinical Laboratory Medicine, Fujita Health University Hospital, Toyoake, Japan; Department of Blood Transfusion Medicine, Fujita Health University Hospital, Toyoake, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Matsuura
authors.forename: Y
authors.initials: Y
authors.lastname: Akatsuka
authors.forename: C
authors.initials: C
authors.lastname: Muramatsu
authors.forename: S
authors.initials: S
authors.lastname: Isogai
authors.forename: Y
authors.initials: Y
authors.lastname: Sugiura
authors.forename: S
authors.initials: S
authors.lastname: Arakawa
authors.forename: M
authors.initials: M
authors.lastname: Murayama
authors.forename: M
authors.initials: M
authors.lastname: Kurahashi
authors.forename: H
authors.initials: H
authors.lastname: Takasuga
authors.forename: T
authors.initials: T
authors.lastname: Oshige
authors.forename: T
authors.initials: T
authors.lastname: Yuba
authors.forename: S
authors.initials: S
authors.lastname: Mizuta
authors.forename: N
authors.initials: N
authors.lastname: Emi
mesh_terms: D000327:Adsorption; D001803:Blood Transfusion / Q000295:instrumentation / Q000379:methods*; D005374:Filtration / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D011188:Potassium / Q000097:blood*
chemical_list: D011188:Potassium
keywords: hyperkalemia; massive transfusion; potassium adsorption filter; rapid transfusion; red cell components