title: Superficial acral fibromyxoma.
abstract: Superficial acral fibromyxoma (SAF), also known as digital fibromyxoma, is a rare soft tissue tumor with a predilection for acral surfaces. Superficial acral fibromyxoma classically presents as a pink to flesh-colored nodule located on the subungual or periungual region of the hands or feet. It is typically slow-growing and asymptomatic, which, coupled with its nonspecific clinical appearance, presents a diagnostic dilemma to the dermatologist. As these features overlap with those of a multitude of differential diagnoses, it is imperative to have a good understanding of the characteristics on which the diagnosis of SAF is based. Superficial acral fibromyxoma was initially described in 2001, since when several case reports and literature reviews have contributed to our current understanding of these tumors. In this article, we will review the history, clinical features, diagnosis, and management of SAF. It is our hope that this systematic approach will help to facilitate the recognition and management of this distinct dermatologic entity.
authors.affiliation: Department of Internal Medicine at Beth Israel Deaconess Hospital, University of Nevada School of Medicine, Boston, MA, USA.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Sawaya
authors.forename: Amor
authors.initials: A
authors.lastname: Khachemoune
mesh_terms: D003937:Diagnosis, Differential; D005350:Fibroma / Q000473:pathology / Q000628:therapy; D005385:Fingers; D006801:Humans; D012983:Soft Tissue Neoplasms / Q000473:pathology / Q000628:therapy; D014034:Toes