title: Atypical presentation of gastrointestinal stromal tumor masquerading as a large duodenal cyst: A case report.
abstract: BACKGROUND
  Gastrointestinal stromal tumors (GIST) are solid tumors. A duodenal GIST masquerading as a cystic lesion has never been reported. We report a large duodenal cyst that finally turned out to be a GIST and was managed without a pancreaticoduodenectomy (PD).
  
  
  METHODS
  A 55 year old lady presented with painful lump in epigastrium. A CT scan revealed a large exophytic cystic lesion from the duodenum with a small solid component. An endoscopy showed a polypoid lesion in the second part of the duodenum adjacent to what looked like a diverticulum. A sleeve duodenal resection, duodeno-duodenostomy and pyloric exclusion was done. The histopathology was duodenal GIST.
  
  
  CONCLUSIONS
  This case posed diagnostic difficulty as it was thought to be either a duplication cyst or a diverticulum of duodenum. The odd point was the small solid component in it. We considered the possibility of a malignancy arising in these settings, which is has been occasionally reported. To our surprise, it turned out to be a GIST. An extensive literature search yielded only four reports that have reported cystic GISTS, all arising from the stomach or pancreas where they have been mistaken for pseudocysts or even a mucinous cystadenocarcinoma of the pancreas. This is the first report of a cystic GIST arising from the duodenum.
  
  
  CONCLUSIONS
  GISTS can present as a predominantly cystic lesion and needs to be considered in the differential diagnosis of cystic lesions of the duodenum. Local resection is an attractive option in select cases and avoids a PD.
authors.affiliation: Dept. of GI Surgery, Surgical Division, Base Hospital, Delhi 110010, India. Electronic address: docam@rediffmail.com.
authors.forename: Ameet
authors.initials: A
authors.lastname: Kumar
authors.affiliation: Dept. of GI Surgery, Surgical Division, Base Hospital, Delhi 110010, India.
authors.forename: C K
authors.initials: CK
authors.lastname: Jakhmola
authors.affiliation: Dept. of GI Surgery, Surgical Division, Base Hospital, Delhi 110010, India.
authors.forename: Shivraj Singh
authors.initials: SS
authors.lastname: Chauhan
authors.affiliation: Dept. of GI Surgery, Surgical Division, Base Hospital, Delhi 110010, India.
authors.forename: Apoorv
authors.initials: A
authors.lastname: Singh
keywords: Cystic degeneration; Duodenal cyst; Duodenal diverticulum; Gastrointestinal tumor; Pyloric exclusion