title: Ionic current inversion in pressure-driven polymer translocation through nanopores.
abstract: We predict streaming current inversion with multivalent counterions in hydrodynamically driven polymer translocation events from a correlation-corrected charge transport theory including charge fluctuations around mean-field electrostatics. In the presence of multivalent counterions, electrostatic many-body effects result in the reversal of the DNA charge. The attraction of anions to the charge-inverted DNA molecule reverses the sign of the ionic current through the pore. Our theory allows for a comprehensive understanding of the complex features of the resulting streaming currents. The underlying mechanism is an efficient way to detect DNA charge reversal in pressure-driven translocation experiments with multivalent cations.
authors.affiliation: Department of Physics, Bilkent University, Ankara 06800, Turkey.|Institut de Recherche Interdisciplinaire USR3078 CNRS and Université Lille I, Parc de la Haute Borne, 52 Avenue de Halley, 59658 Villeneuve d'Ascq, France.
authors.forename: Sahin
authors.initials: S
authors.lastname: Buyukdagli
authors.affiliation: Institut de Recherche Interdisciplinaire USR3078 CNRS and Université Lille I, Parc de la Haute Borne, 52 Avenue de Halley, 59658 Villeneuve d'Ascq, France.
authors.forename: Ralf
authors.initials: R
authors.lastname: Blossey
authors.affiliation: Department of Applied Physics and COMP Center of Excellence, Aalto University School of Science, P.O. Box 11000, FI-00076 Aalto, Espoo, Finland.|Department of Physics, Brown University, Providence, Box 1843, Rhode Island 02912-1843, USA.
authors.forename: T
authors.initials: T
authors.lastname: Ala-Nissila
mesh_terms: D002412:Cations / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D004573:Electrolytes / Q000737:chemistry; D057446:Hydrodynamics; D008956:Models, Chemical; D058608:Nanopores; D055672:Static Electricity
chemical_list: D002412:Cations; D004573:Electrolytes; D004247:DNA