title: Size controlled biogenic silver nanoparticles as antibacterial agent against isolates from HIV infected patients.
abstract: Silver nanoparticles (AgNPs) are synthesized using biological sources due to its high specificity in biomedical applications. Herein, we report the size and shape controlled synthesis of AgNPs using the aqueous extract of blue green alga, Spirulina platensis. Size, shape and elemental composition of AgNPs were characterized using UV-vis spectroscopy, Fluorescence spectroscopy, FT-IR (Fourier Transform-Infrared Spectroscopy), FT-RS (Fourier Transform-Raman Spectroscopy), SEM-EDAX (Scanning Electron Microscopy-Energy Dispersive X-ray analysis) and HR-TEM (High Resolution Transmission Electron Microscopy). AgNPs were stable, well defined and monodispersed (spherical) with an average size of 6 nm. The synthesized AgNPs were tested for its antibacterial potency against isolates obtained from HIV patients.
authors.affiliation: Nanoscience Division, Centre for Ocean Research, Sathyabama University, Chennai 600 119, India.
authors.forename: K S Uma
authors.initials: KS
authors.lastname: Suganya
authors.affiliation: Nanoscience Division, Centre for Ocean Research, Sathyabama University, Chennai 600 119, India. Electronic address: govindtu@gmail.com.
authors.forename: K
authors.initials: K
authors.lastname: Govindaraju
authors.affiliation: Nanoscience Division, Centre for Ocean Research, Sathyabama University, Chennai 600 119, India.
authors.forename: V Ganesh
authors.initials: VG
authors.lastname: Kumar
authors.affiliation: Nanoscience Division, Centre for Ocean Research, Sathyabama University, Chennai 600 119, India.
authors.forename: T Stalin
authors.initials: TS
authors.lastname: Dhas
authors.affiliation: Nanoscience Division, Centre for Ocean Research, Sathyabama University, Chennai 600 119, India.
authors.forename: V
authors.initials: V
authors.lastname: Karthick
authors.affiliation: Nanoscience Division, Department of Zoology, Thiruvalluvar University, Vellore 632 115, India.
authors.forename: G
authors.initials: G
authors.lastname: Singaravelu
authors.affiliation: Department of Microbiology, Dr ALM Post Graduate Institute of Basic Medical Sciences (IBMS), Chennai 600 113, India.
authors.forename: M
authors.initials: M
authors.lastname: Elanchezhiyan
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D015658:HIV Infections / Q000188:drug therapy* / Q000382:microbiology*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008826:Microbial Sensitivity Tests; D010316:Particle Size; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000254:growth & development; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017423:Sequence Analysis, RNA; D012834:Silver / Q000494:pharmacology*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013059:Spectrum Analysis, Raman; D053545:Spirulina / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D012336:RNA, Ribosomal, 16S; D012834:Silver
keywords: 16S rRNA; AgNPs; Antibacterial activity; HIV; Size control; Spirulina platensis