title: Sensitive fluorescence detection of lysozyme using a tris(bipyridine)ruthenium(II) complex containing multiple cyclodextrins.
abstract: A new series of photoactive metallocyclodextrins with increased fluorescence intensity upon binding with ssDNAs/aptamers has been demonstrated to sensitively and selectively detect lysozyme. The detection mechanism relies on the formation of an aptamer-lysozyme complex, which leads to reduction of fluorescence intensity.
authors.affiliation: Department of Chemistry, East China Normal University, No. 500 Dongchuan Road, Shanghai 200241, P. R. China. pghe@chem.ecnu.edu.cn.
authors.forename: Fan
authors.initials: F
authors.lastname: Zhang
authors.forename: Ying-Ying
authors.initials: YY
authors.lastname: Zhao
authors.forename: Hong
authors.initials: H
authors.lastname: Chen
authors.forename: Xiu-Hua
authors.initials: XH
authors.lastname: Wang
authors.forename: Qiong
authors.initials: Q
authors.lastname: Chen
authors.forename: Pin-Gang
authors.initials: PG
authors.lastname: He
mesh_terms: D015082:2,2'-Dipyridyl / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry; D009113:Muramidase / Q000032:analysis* / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D003505:Cyclodextrins; D004277:DNA, Single-Stranded; D009942:Organometallic Compounds; D015082:2,2'-Dipyridyl; D012428:Ruthenium; D009113:Muramidase