title: Cu-Catalyzed selective cascade sp(3) C-H bond oxidative functionalization towards isoxazoline derivatives.
abstract: The first Cu-catalyzed cascade sp(3) C-H bond oxidative functionalization of the 2-ethylazaarenes has been developed. The two different sp(3) C-H bonds in 2-ethylazaarenes are selectively oxidized and four new types of bonds (C=O, C=N, C-C, C-O) are constructed in one operation. Starting from the simple substrates and cheap nitro source, this reaction provides an efficient approach to produce new kinds of isoxazolines.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China. yangshd@lzu.edu.cn.
authors.forename: Gang-Wei
authors.initials: GW
authors.lastname: Wang
authors.forename: Ming-Xing
authors.initials: MX
authors.lastname: Cheng
authors.forename: Ran-Song
authors.initials: RS
authors.lastname: Ma
authors.forename: Shang-Dong
authors.initials: SD
authors.lastname: Yang