title: Survival and prognostic indicators of Budd-Chiari syndrome: a systematic review of 79 studies.
abstract: This paper aimed to systematically review the survival of Budd-Chiari syndrome and to identify the most robust prognostic predictors. Overall, 79 studies were included. According to the treatment modalities, the median 1-, 5- and 10-year survival rate was 93, 83 and 73% after interventional radiological treatment; 81, 75 and 72.5% after surgery other than liver transplantation; 82.5, 70.2 and 66.5% after liver transplantation and 68.1, 44.4% and unavailable after medical therapy alone. According to the publication years, the median 1-, 5- and 10-year survival rate was 68.6, 44.4% and unavailable before 1990; 75.1, 69.5 and 57% during the year 1991-1995; 77, 69.6 and 65.6% during the year 1996-2000; 86.5, 74 and 63.5% during the year 2001-2005 and 90, 82.5 and 72% after 2006. Bilirubin, creatinine and ascites were more frequently identified as significant prognostic factors in univariate analyses. But their statistical significance was less frequently achieved in multivariate analyses.
authors.affiliation: Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang, 110840, China.
authors.forename: Xingshun
authors.initials: X
authors.lastname: Qi
authors.forename: Weirong
authors.initials: W
authors.lastname: Ren
authors.forename: Yongji
authors.initials: Y
authors.lastname: Wang
authors.forename: Xiaozhong
authors.initials: X
authors.lastname: Guo
authors.forename: Daiming
authors.initials: D
authors.lastname: Fan
mesh_terms: D006502:Budd-Chiari Syndrome / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D006801:Humans; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D012307:Risk Factors; D016019:Survival Analysis; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome
keywords: hepatic vein; hepatic venous outflow obstruction; inferior vena cava; predict; prognosis