title: Building a bridge to save a failing ventricle: radiologic evaluation of short- and long-term cardiac assist devices.
abstract: Heart failure is recognized with increasing frequency worldwide and often progresses to an advanced refractory state. Although the reference standard for treatment of advanced heart failure remains cardiac transplantation, the increasing shortage of donor organs and the unsuitability of many patients for transplantation surgery has led to a search for alternative therapies. One such therapy is mechanical circulatory support, which helps relieve the load on the ventricle and thereby allows it to recover function. In addition, there is increasing evidence supporting the use of mechanical devices as a bridge to recovery in patients with acute refractory heart failure. In this article, the imaging evaluation of various commonly used short- and long-term cardiac assist devices is discussed, and their relevant mechanisms of action and physiology are described. Imaging, particularly computed tomography (CT), plays a crucial role in preoperative evaluation for assessment of candidacy for implantation of a left ventricular assist device (LVAD) or total artificial heart (TAH). Also, echocardiography and CT are indispensable in assessment of complications associated with cardiac devices. Complications commonly associated with short-term assist devices include bleeding and malpositioning, whereas long-term devices such as LVADs may be associated with infection, pump thrombosis, and cannula malfunction, as well as bleeding. CT is also commonly performed for preoperative planning before LVAD or TAH explantation, replacement of a device or one of its components, and cardiac transplantation. Online supplemental material is available for this article.
authors.affiliation: From the Sections of Thoracic Imaging (I.M., C.T.L., M.A.B., A.H.E., J.T.A., R.D.R.) and Cardiovascular Imaging (M.A.B.), Imaging Institute, Section of Biomedical Engineering (J.H.K., N.M.), and Section of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute (N.M.), Cleveland Clinic, 9500 Euclid Ave, Room L10, Cleveland, OH 44195.
authors.forename: Inas
authors.initials: I
authors.lastname: Mohamed
authors.forename: Charles T
authors.initials: CT
authors.lastname: Lau
authors.forename: Michael A
authors.initials: MA
authors.lastname: Bolen
authors.forename: Ahmed H
authors.initials: AH
authors.lastname: El-Sherief
authors.forename: Joseph T
authors.initials: JT
authors.lastname: Azok
authors.forename: Jamshid H
authors.initials: JH
authors.lastname: Karimov
authors.forename: Nader
authors.initials: N
authors.lastname: Moazami
authors.forename: Rahul D
authors.initials: RD
authors.lastname: Renapurkar
mesh_terms: D006333:Heart Failure / Q000000981:diagnostic imaging* / Q000601:surgery*; D006352:Heart Ventricles; D006353:Heart-Assist Devices; D006801:Humans; D011474:Prosthesis Design; D011859:Radiography; D013997:Time Factors