title: Influence of smoking on audiological characteristics of hearing function.
abstract: Cigarette smoking and related diseases are global problem of health. Discussion regarding influence of smoking on hearing function has been continued about 20 years. The aim of our study was estimation of relation between smoking and development of cochlear neuritis. Research was conducted at Ltd. National Centre of ENT - Japaridze-Kevanishvili clinic and Ltd.Audiology National Center. The data were collected from September 2011 to December 2013. Cross- sectional observational study was carried out. 600 persons (mean age - 45.4±10.4) were enrolled in the research. After filling the informed consent persons were divided into two groups: smokers (300 smokers, apparently healthy persons, mean age 44.3±10.6 years) and control group (300 healthy non-smoker persons, mean age 46.5±10.2 years). All persons completed a questionnaire, which includes questions about smoking status too. The inclusion criterion in smokers group was a smoking habit during 5 years at least 10 cigarettes per day. Otoscopy and Acoustic impedance test (timpanometry, reflexometry, testing for Eustachian tube conductivity) were used for verification of outer and middle-ear normality. Pure Tone Audiometry was performed for hearing measure and identifies hearing nerve condition. Obtained results were statistically treated by the student's t-distribution. For minimal level of significance was taken p<0,05. In smokers group hearing loss was proved in 31.33% (94 persons) and in control group - in 17.34% (52 persons). Hearing-loss vs. normal-hearing ratio amounted hence to 0.46 (P<0.01) in the smokers group and to 0.21 (P<0.01) in the nonsmokers'. Hearing loss in smokers may be provided by different pathological mechanisms.
authors: Kh A
authors: KhA
authors: Gegenava
authors: Sh V
authors: ShV
authors: Japaridze
authors: Z Sh
authors: ZSh
authors: Kevanishvile
authors: L S
authors: LS
authors: Lomidze
authors: T R
authors: TR
authors: Khechenashvili
mesh_terms: D000328:Adult; D001301:Audiometry, Pure-Tone; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012907:Smoking / Q000009:adverse effects* / Q000453:epidemiology / Q000503:physiopathology*; D000160:Vestibulocochlear Nerve Diseases / Q000139:chemically induced / Q000453:epidemiology / Q000503:physiopathology*