title: Poor prognostic factors in patients who underwent surgery for acute non-occlusive ischemic colitis.
abstract: BACKGROUND
  Ischemic colitis (IC) is a disease with high postoperative morbidity and mortality. Knowledge of the risk factors for postoperative mortality could be helpful in clinical decision making and in optimizing postoperative treatment.
  
  
  METHODS
  From a prospective database, we conducted a retrospective medical record review of 50 patients who underwent surgery for IC between 2003 and 2011 at our institution. We analyzed the causes and potential risk factors for early mortality after surgery for IC.
  
  
  RESULTS
  The early postoperative mortality and morbidity rates were 30.0% (15/50) and 54% (27/50), respectively. The two most common causes of death were multi-organ failure (66.7%, 10/15) and fulminant septic shock (20.0%, 3/15). Univariate analysis showed that postoperative mortality was significantly associated with preoperative nephropathy, coronary artery disease, a previous history of cardiovascular surgery, an ASA score ≥ 4, surgical delay ≥ 3 days, preoperative hemodynamic instability, and use of pre- and intraoperative adrenergic vasopressors. In the multivariate analysis, a previous history of cardiovascular surgery (odds ratio [OR], 8.2; 95% confidence interval [CI], 1.2-56.5) and surgical delay ≥ 3 days (OR, 5.7; 95% CI, 1.2-27.9) were identified as independent risk factors for postoperative mortality.
  
  
  CONCLUSIONS
  Because surgical delay is an avoidable determinant of early mortality, a high index of suspicion and early surgical intervention can increase survival. A routine postoperative evaluation for IC may be helpful in patients with a previous history of cardiovascular surgery.
authors: Department of Surgery, Ulsan University Hospital, 290-3 Jeonha-dong, Dong-gu, Ulsan 682-714 Korea.
authors: Minsu
authors: M
authors: Noh
authors: Department of Surgery, Ulsan University Hospital, 290-3 Jeonha-dong, Dong-gu, Ulsan 682-714 Korea.
authors: Song Soo
authors: SS
authors: Yang
authors: Department of Digestive medicine, Ulsan University Hospital, Ulsan, Korea.
authors: Seok Won
authors: SW
authors: Jung
authors: Department of Digestive medicine, Ulsan University Hospital, Ulsan, Korea.
authors: Jae Ho
authors: JH
authors: Park
authors: Department of Surgery, Ulsan University Hospital, 290-3 Jeonha-dong, Dong-gu, Ulsan 682-714 Korea.
authors: Yeong Cheol
authors: YC
authors: Im
authors: Department of Surgery, Ulsan University Hospital, 290-3 Jeonha-dong, Dong-gu, Ulsan 682-714 Korea.
authors: Kyu Yeol
authors: KY
authors: Kim
keywords: Ischemic colitis; Postoperative mortality; Risk factors; Surgery