title: [Effect of fragmentation and quality of carbohydrates diet on metabolic control parameters in insulin treated type 2 diabetic individuals].
abstract: BACKGROUND
  Currently there is no consensus regarding fragmentation, quantity and quality of carbohydrates (CHO) that should be followed by insulin treated type 2 diabetic individuals (ITT2D).
  
  
  OBJECTIVE
  To determine the relationship between the meal times, quality of available CHO in every meal and the metabolic control parameters in ITT2D individuals with a single or double dose of intermediate-acting insulin.
  
  
  METHODS
  40 ITT2D individuals were evaluated, using food surveys to obtain the quantity of CHO, glycemic index (GI), glycemic load (GL) in every meal and meal times. The metabolic control was determined through lab exams (glycated hemoglobin; HbA1c, venous fasting glycaemia) and fasting (FBG), preprandial (PreG), postprandial (PostG) and bed time (BTG) capilar glycaemia using a glucometer. Statistical analysis were applied considering significant as p<0,05.
  
  
  RESULTS
  Individuals recorded an average of 4,9 ± 1,1 meals a day. It was found an asociation between lunch GL and Post G (r=0,317; p<0,05) and BTG (r=0,321; p<0,05). BTG was inversely correlated with the meals' distribution (r = -0,346; p<0,05) and there was a trend to show lower values of BTG with individuals conducting ≥5 meals per day. It was observed that FBG predicts a 65%the variability of HbA1c (r =0,805; r2 =0,648; p<0,001).
  
  
  CONCLUSIONS
  The meal times in ITT2D individuals with s single or doublé dose of intermédiate-acting insulin could improve BTG.
authors: Carrera Nutrición y Dietética, Facultad de Farmacia, Universidad de Valparaíso, Valparaíso.. claudia.vega@uv.cl.
authors: Verónica
authors: V
authors: Sambra Vásquez
authors: Carrera Nutrición y Dietética, Facultad de Farmacia, Universidad de Valparaíso, Valparaíso.. claudia.vega@uv.cl.
authors: Carolina
authors: C
authors: Tapia Fernández
authors: Escuela de Nutrición, Facultad de Farmacia, Universidad de Valparaíso, Valparaíso. Chile.. claudia.vega@uv.cl.
authors: Claudia
authors: C
authors: Vega Soto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000178:diet therapy* / Q000188:drug therapy; D004040:Dietary Carbohydrates; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D006943:Hyperglycemia / Q000097:blood; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin