title: Estimation of Residual Peritoneal Volume Using Technetium-99m Sulfur Colloid Scintigraphy.
abstract: Residual peritoneal volume (RPV) may contribute in the development of ultrafiltration failure in patients with normal transcapillary ultrafiltration. The aim of this study was to estimate the RPV using intraperitoneal technetium-99m Sulfur Colloid (Tc). Twenty patients on peritoneal dialysis were studied. RPV was estimated by: 1) intraperitoneal instillation of Tc (RPV-Tc) and 2) classic Twardowski calculations using endogenous solutes, such as urea (RPV-u), creatinine (RPV-cr), and albumin (RPV-alb). Each method's reproducibility was assessed in a subgroup of patients in two consecutive measurements 48 h apart. Both methods displayed reproducibility (r = 0.93, p = 0.001 for RPVTc and r = 0.90, p = 0.001 for RPV-alb) between days 1 and 2, respectively. We found a statistically significant difference between RPV-Tc and RPV-cr measurements (347.3 ± 116.7 vs. 450.0 ± 67.8 ml; p =0.001) and RPV-u (515.5 ± 49.4 ml; p < 0.001), but not with RPV-alb (400.1 ± 88.2 ml; p = 0.308). A good correlation was observed only between RPV-Tc and RPV-alb (p < 0.001). The Tc method can estimate the RPV as efficiently as the high molecular weight endogenous solute measurement method. It can also provide an imaging estimate of the intraperitoneal distribution of RPV.
authors: From the *Nephrology Department, General Hospital of Artas, Arta, Greece; †Department of Nuclear Medicine, and ‡Department of Nephrology, University Hospital of Ioannina, Ioannina, Greece.
authors: Konstantinos P
authors: KP
authors: Katopodis
authors: Andrew D
authors: AD
authors: Fotopoulos
authors: Olga C
authors: OC
authors: Balafa
authors: Spyridon Th
authors: ST
authors: Tsiouris
authors: Eleni G
authors: EG
authors: Triandou
authors: Jichad B
authors: JB
authors: Al-Bokharhli
authors: Athanasios C
authors: AC
authors: Kitsos
authors: Evagelia C
authors: EC
authors: Dounousi
authors: Konstantinos C
authors: KC
authors: Siamopoulos
mesh_terms: D003102:Colloids; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000379:methods*; D011877:Radionuclide Imaging / Q000379:methods*; D051437:Renal Insufficiency / Q000000981:diagnostic imaging*; D013455:Sulfur; D013667:Technetium
chemical_list: D003102:Colloids; D013455:Sulfur; D013667:Technetium