title: Even mild depression is associated with among-day blood pressure variability, including masked non-dipping assessed by 7-d/24-h ambulatory blood pressure monitoring.
abstract: The effect of mild depression on blood pressure (BP) was assessed in 116 Japanese (32-79 years). As compared to non-depressive (Geriatric Depression Scale, GDS-15 score <5) subjects, mild depressives (GDS-15 score: 1-15) had shorter sleep duration (p = 0.021), lower subjective quality of life (health: p = 0.016; life satisfaction: p < 0.001; and happiness: p < 0.001), and higher 7-d systolic BP (p < 0.05). "Masked non-dipping" (dipping on day 1, but non-dipping on at least 1 of the following 6 d) was more frequent among depressive than non-depressive normotensives (p = 0.008). Among-day BP variability may underlie cardiovascular disease accompanying a key component of psychological depression.
authors: Department of Chronomics and Gerontology, Tokyo Women's Medical University , Tokyo , Japan .
authors: Kiyotaka
authors: K
authors: Okajima
authors: Gaku
authors: G
authors: Yamanaka
authors: Sachiko
authors: S
authors: Oinuma
authors: Tomoko
authors: T
authors: Kikichi
authors: Takashi
authors: T
authors: Yamanaka
authors: Kuniaki
authors: K
authors: Otsuka
authors: Germaine
authors: G
authors: Cornelissen
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory / Q000379:methods*; D002940:Circadian Rhythm / Q000502:physiology*; D003863:Depression / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D008019:Life Style; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012890:Sleep / Q000502:physiology*; D013997:Time Factors
keywords: 7-d/24-h ambulatory blood pressure monitoring; among-day blood pressure variability; home blood pressure; masked non-dipping; mildly depressed mood