title: [Assessing quality of life of patients with stroke using EQ-5D and SF-12].
abstract: OBJECTIVE
  To compare.the results of EQ-SD and SF-12 for assessing health-related quality of life in stroke patients.
  
  
  METHODS
  EQ-5D and SF-12 were administered to 598 ischemic stroke patients through face-to-face interviews. Differences in PCS-12 and MCS-12 scores across different levels of EQ-5D dimensions were tested using analysis of variance (ANOVA). The EQ-5D index and visual analogue scale/score (VAS) scores of respondents were compared between those with higher than and lower than median SF-12 scores using student t-test. Pearson correlations between PCS-12 and EQ-5D scores were tested.
  
  
  RESULTS
  PCS-12 and MCA-12 scores varied across different levels of EQ-5D dimensional scores, except for pain/discomfort. EQ-5D and VAS scores varied between those with high and low SF-12 scores. No significant differences in EQ-5D index and VAS scores were found in the EQ-5D indicated healthy respondents between those with high and low SF-12 scores (P>0.05). PCS-12 was positively correlated with EQ-5D index and VAS scores, with r=0.15 (P<0.001) and r=0.33 (P< 0.001), respectively. MCS-12 was also positively correlated with EQ-5D index and VAS score, with r=0.17 (P<0.001) and r = 0.13 (P<0.001), respectively.
  
  
  CONCLUSIONS
  Both instruments are valid measurements for assessing quality of life. The SF-12 appeared to be more sensitive to differences in health status. EQ-5D is preferable if both quality of life assessment and health economics study are to be conducted.
authors: Meng-dong
authors: MD
authors: Ran
authors: Bing-qing
authors: BQ
authors: Liu
authors: Long-mei
authors: LM
authors: Chen
authors: Cai-rong
authors: CR
authors: Zhu
mesh_terms: D000704:Analysis of Variance; D006304:Health Status; D006801:Humans; D011788:Quality of Life; D020521:Stroke; D011795:Surveys and Questionnaires