title: Metal-free nitro-carbocyclization of 1,6-enynes with (t)BuONO and TEMPO.
abstract: A novel and convenient metal-free nitration and cyclization of 1,6-enynes has been developed. Two C-C bonds and one C-N bond were constructed in one process in this reaction. This transformation is proven to have relatively good functional-group applicability and can be scaled up to gram quantities in satisfactory yields. According to the following experimental facts and related literature reports, a radical pathway was involved in this transformation.
authors: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu, China. liangym@lzu.edu.cn.
authors: Xin-Hua
authors: XH
authors: Hao
authors: Pin
authors: P
authors: Gao
authors: Xian-Rong
authors: XR
authors: Song
authors: Yi-Feng
authors: YF
authors: Qiu
authors: Dong-Po
authors: DP
authors: Jin
authors: Xue-Yuan
authors: XY
authors: Liu
authors: Yong-Min
authors: YM
authors: Liang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry*; D003497:Cyclic N-Oxides / Q000737:chemistry*; D003500:Cyclization; D009573:Nitrites / Q000737:chemistry*
chemical_list: D000475:Alkenes; D000480:Alkynes; D003497:Cyclic N-Oxides; D009573:Nitrites; C003959:TEMPO