title: [Biochemical characteristics associated with diabetes mellitus one year after myocardial infarction].
abstract: OBJECTIVE
  To evaluate the most informative parameters of adipokine, anti-inflammatory, and prothrombogenic status associated with diabetes mellitus.
  
  
  METHODS
  The study included 200 patients with myocardial infarction (MI) in whom markers of adipokine status, grelin, anti-inflammatory factors, CRP and plasminogen activator inhibitor were measured by biochemical methods on days 1 and 12 after admission.
  
  
  RESULTS
  In the period of acute MI, the adipokine status was disturbed, FFA and grelin levels decreased, pro-inflammatory and thrombotic potential increased. Patients who developed diabetes within 1 year after MI were characterized by more pronounced changes of the parameters of interest.
  
  
  CONCLUSIONS
  Adiponectin, retinol-binding protein, grelin, TNF-α, and plasminogen activator inhibitor are the most informative biochemical parameters associated with diabetes mellitus developing 1 year after MI.
authors: O L
authors: OL
authors: Barbarash
authors: O V
authors: OV
authors: Gruzdeva
authors: O E
authors: OE
authors: Akbasheva
authors: E V
authors: EV
authors: Belik
authors: E G
authors: EG
authors: Uchasova
authors: V N
authors: VN
authors: Karetnikova
authors: T S
authors: TS
authors: Fedorova
mesh_terms: D052242:Adiponectin / Q000378:metabolism*; D015415:Biomarkers / Q000378:metabolism; D002097:C-Reactive Protein / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000378:metabolism; D005260:Female; D005500:Follow-Up Studies; D054439:Ghrelin / Q000378:metabolism*; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000378:metabolism / Q000503:physiopathology; D017395:Plasminogen Activator Inhibitor 1 / Q000378:metabolism*; D011237:Predictive Value of Tests; D016016:Proportional Hazards Models; D012044:Regression Analysis; D012177:Retinol-Binding Proteins / Q000378:metabolism*; D013927:Thrombosis / Q000378:metabolism; D013997:Time Factors; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
chemical_list: D052242:Adiponectin; D015415:Biomarkers; D054439:Ghrelin; D017395:Plasminogen Activator Inhibitor 1; D012177:Retinol-Binding Proteins; D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein