title: Dosimetric models of the eye and lens of the eye and their use in assessing dose coefficients for ocular exposures.
abstract: Based upon recent epidemiological studies of ocular exposure, the Main Commission of the International Commission on Radiological Protection (ICRP) in ICRP Publication 118 states that the threshold dose for radiation-induced cataracts is now considered to be approximately 0.5 Gy for both acute and fractionated exposures. Consequently, a reduction was also recommended for the occupational annual equivalent dose to the lens of the eye from 150 mSv to 20 mSv, averaged over defined periods of 5 years. To support ocular dose assessment and optimisation, Committee 2 included Annex F within ICRP Publication 116 . Annex F provides dose coefficients - absorbed dose per particle fluence - for photon, electron, and neutron irradiation of the eye and lens of the eye using two dosimetric models. The first approach uses the reference adult male and female voxel phantoms of ICRP Publication 110. The second approach uses the stylised eye model of Behrens et al., which itself is based on ocular dimensional data given in Charles and Brown. This article will review the data and models of Annex F with particular emphasis on how these models treat tissue regions thought to be associated with stem cells at risk.
authors: University of Florida, Gainesville, FL, USA wbolch@ufl.edu.
authors: W E
authors: WE
authors: Bolch
authors: Braunschweig, Germany.
authors: G
authors: G
authors: Dietze
authors: Helmholtz Zentrum Munchen, Germany.
authors: N
authors: N
authors: Petoussi-Henss
authors: Helmholtz Zentrum Munchen, Germany.
authors: M
authors: M
authors: Zankl
mesh_terms: D002386:Cataract / Q000209:etiology; D004307:Dose-Response Relationship, Radiation; D005123:Eye / Q000528:radiation effects*; D005260:Female; D017408:Guidelines as Topic; D006801:Humans; D007908:Lens, Crystalline / Q000528:radiation effects; D008297:Male; D016273:Occupational Exposure / Q000517:prevention & control*; D011829:Radiation Dosage; D011835:Radiation Protection; D011874:Radiometry
keywords: Cataract; Dose conversion coefficient; Eye lens; Ocular exposure