title: Penicillium marneffei infection in a lung transplant recipient.
abstract: Penicillium marneffei is a thermally dimorphic fungus that can cause severe opportunistic infections in endemic regions of Southeast Asia, particularly in individuals infected with human immunodeficiency virus-1, but has rarely been reported in solid organ transplant recipients. Herein, we report the first case, to our knowledge, of P. marneffei infection in a lung transplant recipient, occurring in a 41-year-old woman 28 months post lung transplantation, after recent travel to Vietnam. We have reviewed the literature to derive some management principles for this rare infection in this clinical context. The number of P. marneffei infections in transplant recipients may increase, as a result of increasing rates of transplantation and travel to endemic areas.
authors: Department of Microbiology and Infectious Diseases, Royal Perth Hospital, Perth, Western Australia, Australia.
authors: A
authors: A
authors: Stathakis
authors: WA Advanced Lung Disease and Lung Transplant Unit, Royal Perth Hospital, Perth, Western Australia, Australia.
authors: K P
authors: KP
authors: Lim
authors: Department of Microbiology and Infectious Diseases, Royal Perth Hospital, Perth, Western Australia, Australia.
authors: P
authors: P
authors: Boan
authors: WA Advanced Lung Disease and Lung Transplant Unit, Royal Perth Hospital, Perth, Western Australia, Australia.
authors: M
authors: M
authors: Lavender
authors: WA Advanced Lung Disease and Lung Transplant Unit, Royal Perth Hospital, Perth, Western Australia, Australia.
authors: J
authors: J
authors: Wrobel
authors: WA Advanced Lung Disease and Lung Transplant Unit, Royal Perth Hospital, Perth, Western Australia, Australia.
authors: M
authors: M
authors: Musk
authors: Department of Microbiology and Infectious Diseases, Royal Perth Hospital, Perth, Western Australia, Australia.|Department of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia.
authors: C H
authors: CH
authors: Heath
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D016040:Lung Transplantation; D009181:Mycoses / Q000000981:diagnostic imaging / Q000382:microbiology*; D010407:Penicillium / Q000302:isolation & purification*; D066027:Transplant Recipients; D014195:Travel; D016896:Treatment Outcome; D014744:Vietnam; D065819:Voriconazole / Q000008:administration & dosage*
chemical_list: D000935:Antifungal Agents; D065819:Voriconazole
keywords: Penicillium marneffei; Talaromyces marneffei; itraconazole; liposomal amphotericin B; renal transplant; travel; voriconazole