title: Management of cancer in pregnancy.
abstract: A multidisciplinary discussion is necessary to tackle a complex and infrequent medical problem such as cancer occurring during pregnancy. Pregnancy does not predispose to cancer, but cancers occurring in women of reproductive age are encountered during pregnancy. Ultrasonography and magnetic resonance imaging are the preferred staging examinations, but also a sentinel node staging procedure is possible during pregnancy. Standard cancer treatment is aimed for. Operations can safely be performed during pregnancy, but surgery of genital cancers can be challenging. The observation that chemotherapy administered during the second or third trimester of pregnancy, that is, after the period of organogenesis, has little effect on the long-term outcome of children adds to the therapeutic armamentarium during pregnancy. Cancer treatment during pregnancy adds in the continuation of the pregnancy and the prevention of prematurity.
authors: Gynecological Oncology, Department of Obstetrics and Gynecology, University Hospitals Leuven, Department of Oncology, KU Leuven, Leuven, Belgium. Electronic address: frederic.amant@uzleuven.be.
authors: Frédéric
authors: F
authors: Amant
authors: Gynecological Oncology, Department of Obstetrics and Gynecology, University Hospitals Leuven, Department of Oncology, KU Leuven, Leuven, Belgium.
authors: Sileny N
authors: SN
authors: Han
authors: Department of Obstetrics and Gynecology, Cliniques Universitaires St Luc, UCL, Brussels, Belgium.
authors: Mina Mhallem
authors: MM
authors: Gziri
authors: Gynecological Oncology, Department of Obstetrics and Gynecology, University Hospitals Leuven, Department of Oncology, KU Leuven, Leuven, Belgium.
authors: Tineke
authors: T
authors: Vandenbroucke
authors: Gynecological Oncology, Department of Obstetrics and Gynecology, University Hospitals Leuven, Department of Oncology, KU Leuven, Leuven, Belgium.
authors: Magali
authors: M
authors: Verheecke
authors: Department of Obstetrics and Gynecology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
authors: Kristel
authors: K
authors: Van Calsteren
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology* / Q000628:therapy*; D011297:Prenatal Exposure Delayed Effects; D011379:Prognosis; D011878:Radiotherapy; D013514:Surgical Procedures, Operative
chemical_list: D000970:Antineoplastic Agents
keywords: cancer; chemotherapy; pregnancy; radiotherapy; surgery