title: Anatomical confirmation of computed tomography-based diagnosis of the atherosclerosis discovered in 17th century Korean mummy.
abstract: In the present study on a newly discovered 17th century Korean mummy, computed tomography (CT) revealed multiple aortic calcifications within the aortic wall that were indicative of ancient atherosclerosis. The CT-based findings were confirmed by our subsequent post-factum dissection, which exhibited possible signs of the disease including ulcerated plaques, ruptured hemorrhages, and intimal thickening where the necrotic core was covered by the fibrous cap. These findings are strong indicators that the mummy suffered from aortic atherosclerosis during her lifetime. The present study is a good example of how CT images of vascular calcifications can be a useful diagnostic tool in forming at least preliminary diagnoses of ancient atherosclerosis.
authors: Department of Anatomy, Dankook University College of Medicine, Cheonan, Korea.
authors: Myeung Ju
authors: MJ
authors: Kim
authors: Department of Anatomy, Ewha Womans University School of Medicine, Seoul, Korea.
authors: Yi-Suk
authors: YS
authors: Kim
authors: Department of Anatomy, Seoul National University College of Medicine, Seoul, Korea; Institute of Forensic Science, Seoul National University College of Medicine, Seoul, Korea.
authors: Chang Seok
authors: CS
authors: Oh
authors: Department of Pathology, Dankook University College of Medicine, Cheonan, Korea.
authors: Jai-Hyang
authors: JH
authors: Go
authors: Department of Radiology, Seoul National University Hospital, Bundang, Korea.
authors: In Sun
authors: IS
authors: Lee
authors: Department of Wood and Paper Science, Chungbuk National University, Cheongju, Korea.
authors: Won-Kyu
authors: WK
authors: Park
authors: Gaya National Research Institute of Cultural Heritage, Changwon, Korea.
authors: Seok-Min
authors: SM
authors: Cho
authors: National Research Institute of Cultural Heritage, Cultural Heritage Science Center, Daejeon, Korea.
authors: Soon-Kwan
authors: SK
authors: Kim
authors: Department of Anatomy, Seoul National University College of Medicine, Seoul, Korea; Institute of Forensic Science, Seoul National University College of Medicine, Seoul, Korea.
authors: Dong Hoon
authors: DH
authors: Shin
mesh_terms: D034841:Abdominal Cavity / Q000000981:diagnostic imaging / Q000473:pathology; D000328:Adult; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging / Q000473:pathology; D044466:Asian People; D050197:Atherosclerosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D008875:Middle Aged; D009106:Mummies / Q000000981:diagnostic imaging* / Q000473:pathology*; D014057:Tomography, X-Ray Computed