title: Nerve growth factor and inducible nitric oxide synthase expression in the mesencephalon and diencephalon, as well as visual- and auditory-related nervous tissues, in a macaque model of type 2 diabetes.
abstract: The present study detected distribution and expression of nerve growth factor and inducible nitric oxide synthase in the mesencephalon and diencephalon, as well as visual- and auditory-related nervous tissues, in a macaque model of type 2 diabetes using immunohistochemistry. Results showed that nerve growth factor expression decreased, but inducible nitric oxide synthase expression increased, in the mesencephalon and diencephalon, as well as visual- and auditory- related nervous tissues. These results suggested that nerve growth factor and inducible nitric oxide synthase play an important role in regulating the development of diabetic visual- and auditory-related diseases.
authors: College of Veterinary Medicine, Sichuan Agricultural University/Key Laboratory of Animal Disease and Human Health of Sichuan Province, Ya'an 625014, Sichuan Province, China ; Experimental Animal Engineering Center, Sichuan Agricultural University/Provenance Source De pot of Macaque for National Experiment, Ya'an 625014, Sichuan Province, China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, Sichuan Province, China.
authors: Qihui
authors: Q
authors: Luo
authors: College of Veterinary Medicine, Sichuan Agricultural University/Key Laboratory of Animal Disease and Human Health of Sichuan Province, Ya'an 625014, Sichuan Province, China ; Experimental Animal Engineering Center, Sichuan Agricultural University/Provenance Source De pot of Macaque for National Experiment, Ya'an 625014, Sichuan Province, China.
authors: Wentao
authors: W
authors: Liu
authors: College of Veterinary Medicine, Sichuan Agricultural University/Key Laboratory of Animal Disease and Human Health of Sichuan Province, Ya'an 625014, Sichuan Province, China ; Experimental Animal Engineering Center, Sichuan Agricultural University/Provenance Source De pot of Macaque for National Experiment, Ya'an 625014, Sichuan Province, China.
authors: Jingyao
authors: J
authors: Chen
authors: College of Veterinary Medicine, Sichuan Agricultural University/Key Laboratory of Animal Disease and Human Health of Sichuan Province, Ya'an 625014, Sichuan Province, China ; Experimental Animal Engineering Center, Sichuan Agricultural University/Provenance Source De pot of Macaque for National Experiment, Ya'an 625014, Sichuan Province, China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, Sichuan Province, China.
authors: Mingshu
authors: M
authors: Wang
authors: Experimental Animal Engineering Center, Sichuan Agricultural University/Provenance Source De pot of Macaque for National Experiment, Ya'an 625014, Sichuan Province, China ; Sinopharm Center for Safety Evaluation and Research, Chengdu 610051, Sichuan Province, China.
authors: Wen
authors: W
authors: Zeng
authors: College of Veterinary Medicine, Sichuan Agricultural University/Key Laboratory of Animal Disease and Human Health of Sichuan Province, Ya'an 625014, Sichuan Province, China ; Experimental Animal Engineering Center, Sichuan Agricultural University/Provenance Source De pot of Macaque for National Experiment, Ya'an 625014, Sichuan Province, China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, Sichuan Province, China.
authors: Zhengli
authors: Z
authors: Chen
authors: College of Veterinary Medicine, Sichuan Agricultural University/Key Laboratory of Animal Disease and Human Health of Sichuan Province, Ya'an 625014, Sichuan Province, China ; Experimental Animal Engineering Center, Sichuan Agricultural University/Provenance Source De pot of Macaque for National Experiment, Ya'an 625014, Sichuan Province, China ; Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, Sichuan Province, China.
authors: Anchun
authors: A
authors: Cheng
keywords: diencephalon; immunohistochemistry; inducible nitric oxide synthase; mesencephalon; nerve growth factor; neural regeneration; optic nerve; type 2 diabetes