title: Magnetic resonance imaging pattern recognition in sporadic inclusion-body myositis.
abstract: BACKGROUND
  In sporadic inclusion-body myositis (IBM), additional tools are needed to confirm the diagnosis, particularly in clinically atypical or pathologically unproven patients. The aims of this study were to define the pattern of muscle MRI in IBM and to assess its accuracy in differentiating IBM from other myopathies that overlap with it clinically or pathologically.
  
  
  METHODS
  Blind assessment was done on the scans of 17 definite IBM, 2 possible IBM, and 118 patients with other myopathies.
  
  
  RESULTS
  The diagnostic accuracy to detect definite IBM was 95% for the typical pattern (with 100% specificity) and 97% for both typical and consistent patterns (with 97% specificity).
  
  
  CONCLUSIONS
  Muscle MRI is an accurate tool for diagnostic work-up of suspected IBM patients and may be particularly helpful in patients with early disease or who lack the classical IBM pathology.
authors: Don Carlo Gnocchi ONLUS Foundation, Italy.
authors: Giorgio
authors: G
authors: Tasca
authors: Institute of Neurology, Catholic University School of Medicine, Rome, Italy.
authors: Mauro
authors: M
authors: Monforte
authors: Institute of Neurology, Catholic University School of Medicine, Rome, Italy.
authors: Chiara
authors: C
authors: De Fino
authors: Department of Neurology, University Hospital Bergmannsheil, Ruhr University, Bochum, Germany.
authors: Rudolf A
authors: RA
authors: Kley
authors: Institute of Neurology, Catholic University School of Medicine, Rome, Italy.
authors: Enzo
authors: E
authors: Ricci
authors: Institute of Neurology, Catholic University School of Medicine, Rome, Italy.
authors: Massimiliano
authors: M
authors: Mirabella
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology*; D018979:Myositis, Inclusion Body / Q000145:classification / Q000175:diagnosis* / Q000503:physiopathology; D012680:Sensitivity and Specificity
keywords: MRI; inclusion-body myositis; muscle pattern recognition; sensitivity; specificity