title: Noninvasive Fractional Flow Reserve for the Diagnosis of Lesion-specific Ischemia: A Case Example.
abstract: A physically active 52-year-old male with atypical chest pain was referred to our department. A coronary computed tomography angiography (CCTA) showed a stenotic plaque in the mid left anterior descending coronary artery (LAD). A rest-stress Rubidium-82 myocardial perfusion was normal. One year later the patient sustained a cardiac arrest and percutaneous coronary intervention of the mid-LAD was successfully performed. The original CCTA data were submitted for noninvasive determination of fractional flow reserve (FFRCT) revealing an ischemia-producing lesion in the mid-LAD. This case demonstrates the inherent limitations of assessing lesion-specific ischemia. FFRCT shows promise as a new method for future selection of patients for coronary angiography.
authors: Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
authors: Jesper Møller
authors: JM
authors: Jensen
authors: Department of Nuclear Medicine, Aarhus University Hospital, Aarhus, Denmark.
authors: Lars Christian
authors: LC
authors: Gormsen
authors: Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
authors: Henning
authors: H
authors: Mølgaard
authors: Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
authors: Bjarne Linde
authors: BL
authors: Nørgaard
keywords: Coronary artery disease; fractional flow reserve; nuclear medicine