title: One-pot Sonogashira coupling-cyclization toward regioselective synthesis of benzosultams.
abstract: A one-pot method for the Sonogashira coupling and cyclization of 2-bromobenzenesulfonamides and terminal alkynes is presented. This method allows access to a variety of substituted benzosultams regioselectively in excellent yields. The reasons for regioselectivity are interpreted through density functional theory (DFT) studies.
authors: Department of Chemistry, Visva-Bharati University, Santiniketan 731235, India.
authors: Sudarshan
authors: S
authors: Debnath
authors: Department of Chemistry, Visva-Bharati University, Santiniketan 731235, India.
authors: Shovan
authors: S
authors: Mondal
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D011789:Quantum Theory; D013237:Stereoisomerism; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D001555:Benzene Derivatives; D013449:Sulfonamides