title: Unravelling the hidden ancestry of American admixed populations.
abstract: The movement of people into the Americas has brought different populations into contact, and contemporary American genomes are the product of a range of complex admixture events. Here we apply a haplotype-based ancestry identification approach to a large set of genome-wide SNP data from a variety of American, European and African populations to determine the contributions of different ancestral populations to the Americas. Our results provide a fine-scale characterization of the source populations, identify a series of novel, previously unreported contributions from Africa and Europe and highlight geohistorical structure in the ancestry of American admixed populations.
authors: 1] Institute of Legal Medicine, Catholic University, Largo F. Vito 1, Rome 00168, Italy [2] Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK.
authors: Francesco
authors: F
authors: Montinaro
authors: 1] Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK [2] Wellcome Trust Center for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.
authors: George B J
authors: GB
authors: Busby
authors: Institute of Legal Medicine, Catholic University, Largo F. Vito 1, Rome 00168, Italy.
authors: Vincenzo L
authors: VL
authors: Pascali
authors: 1] Wellcome Trust Center for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK [2] Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK.
authors: Simon
authors: S
authors: Myers
authors: UCL Genetics Institute, University College London, WC1E 6BT Gower Street, UK.
authors: Garrett
authors: G
authors: Hellenthal
authors: Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK.
authors: Cristian
authors: 0000000193489084
authors: C
authors: Capelli
mesh_terms: D044467:American Indian or Alaska Native / Q000235:genetics*; D044466:Asian People / Q000235:genetics*; D044383:Black People / Q000235:genetics*; D002489:Central America; D030541:Databases, Genetic; D004641:Emigration and Immigration; D005828:Genetics, Population; D015894:Genome, Human / Q000235:genetics*; D063426:Human Migration; D006801:Humans; D009656:North America; D020641:Polymorphism, Single Nucleotide; D013020:South America; D044465:White People / Q000235:genetics*