title: [A case of stage IV breast cancer with improved cancer pain using bevacizumab and paclitaxel].
abstract: A 65-year-old woman with a right breast tumor and right arm pain was seen in our hospital. She was diagnosed with scirrhous carcinoma (Stage IV, hormone receptor-positive, and HER2-negative) with pleural effusion and metastasis to the lung, liver, bone, and multiple lymph nodes. Systemic chemotherapy with biweekly bevacizumab and weekly paclitaxel was administered, and an opioid (oxycodone 40 mg/day) was administered for pain control. At the end of the first course, the patient's pain was improved, and the opioid dose was reduced (oxycodone 20 mg/day). The patient had a partial response (PR) over 24 treatment courses (1 year 10 months), and good pain control was obtained. Bevacizumab and paclitaxel therapy successfully brought about a rapid and good response and improved the patient's quality of life as palliative chemo- therapy.
authors: Dept. of Surgery, Yamagata Prefectural Shinjo Hospital.
authors: Tomoharu
authors: T
authors: Ishiyama
authors: Akira
authors: A
authors: Jinguu
authors: Hidekazu
authors: H
authors: Matsumoto
authors: Jirou
authors: J
authors: Kikuchi
authors: Tomonobu
authors: T
authors: Suzuki
mesh_terms: D000368:Aged; D000701:Analgesics, Opioid / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D000068258:Bevacizumab; D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D010098:Oxycodone / Q000627:therapeutic use; D017239:Paclitaxel / Q000008:administration & dosage; D010146:Pain / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000701:Analgesics, Opioid; D061067:Antibodies, Monoclonal, Humanized; D000068258:Bevacizumab; D010098:Oxycodone; D017239:Paclitaxel