title: [The system of hemostasis in patients with diabetic foot syndrome undergoing surgical treatment].
abstract: Characteristics of hemostasis system were studied in 185 patients with diabetic foot syndrome undergoing surgical treatment. Disturbances of procoagulative activity persisted within days 1 and 5 after surgery in patients with complicated forms of DFS due to enhanced formation of blood and tissue prothrombinase; simultaneously, the formerly increased fibrinogen level decreased by virtue of intravascular blood coagulation. The activity of natural anticoagulants (antithrombin 111, proteins C andS) continued to be low as a result of their utilization to activate coagulation processes. Resistance of Va factor to activated C protein remained as high as preoperatively. XIIa-Hageman-dependentfJibrinolysis was suppressed and showed no tendency toward recovery.
authors: Iu G
authors: IuG
authors: Shapkin
authors: E V
authors: EV
authors: Efimov
authors: A V
authors: AV
authors: Khoroshkevich
mesh_terms: D000328:Adult; D017719:Diabetic Foot / Q000097:blood* / Q000601:surgery; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D016896:Treatment Outcome