title: Hierarchically functionalized magnetic core/multishell particles and their postsynthetic conversion to polymer capsules.
abstract: The controlled synthesis of hierarchically functionalized core/multishell particles is highly desirable for applications in medicine, catalysis, and separation. Here, we describe the synthesis of hierarchically structured metal-organic framework multishells around magnetic core particles (magMOFs) via layer-by-layer (LbL) synthesis. The LbL deposition enables the design of multishell systems, where each MOF shell can be modified to install different functions. Here, we used this approach to create controlled release capsules, in which the inner shell serves as a reservoir and the outer shell serves as a membrane after postsynthetic conversion of the MOF structure to a polymer network. These capsules enable the controlled release of loaded dye molecules, depending on the surrounding media.
authors: Sophia
authors: S
authors: Schmitt
authors: Martin
authors: M
authors: Silvestre
authors: Manuel
authors: M
authors: Tsotsalas
authors: Anna-Lena
authors: AL
authors: Winkler
authors: Artak
authors: A
authors: Shahnas
authors: ∥Institute of Organic Chemistry (IOC), Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany.
authors: Sylvain
authors: S
authors: Grosjean
authors: Fabrice
authors: F
authors: Laye
authors: Hartmut
authors: H
authors: Gliemann
authors: Joerg
authors: J
authors: Lahann
authors: ∥Institute of Organic Chemistry (IOC), Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany.
authors: Stefan
authors: S
authors: Bräse
authors: Matthias
authors: M
authors: Franzreb
authors: Christof
authors: C
authors: Wöll
mesh_terms: D002214:Capsules; D060326:Chemistry Techniques, Synthetic; D004396:Coloring Agents / Q000737:chemistry; D003692:Delayed-Action Preparations; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry*; D059346:Magnets / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*
chemical_list: D002214:Capsules; D004396:Coloring Agents; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D009942:Organometallic Compounds; D011108:Polymers
keywords: click-chemistry; drug release; layer-by-layer synthesis; metal−organic framework (MOF); polymer capsules