title: Bacterial transfer RNAs.
abstract: Transfer RNA is an essential adapter molecule that is found across all three domains of life. The primary role of transfer RNA resides in its critical involvement in the accurate translation of messenger RNA codons during protein synthesis and, therefore, ultimately in the determination of cellular gene expression. This review aims to bring together the results of intensive investigations into the synthesis, maturation, modification, aminoacylation, editing and recycling of bacterial transfer RNAs. Codon recognition at the ribosome as well as the ever-increasing number of alternative roles for transfer RNA outside of translation will be discussed in the specific context of bacterial cells.
authors: Department of Microbiology and the Center for RNA Biology, Ohio State University, Columbus, Ohio 43210, USA.
authors: Jennifer
authors: J
authors: Shepherd
authors: Department of Microbiology and the Center for RNA Biology, Ohio State University, Columbus, Ohio 43210, USA ibba.1@osu.edu.
authors: Michael
authors: M
authors: Ibba
mesh_terms: D003062:Codon / Q000235:genetics / Q000378:metabolism; D015964:Gene Expression Regulation, Bacterial; D012329:RNA, Bacterial / Q000235:genetics / Q000378:metabolism*; D012343:RNA, Transfer / Q000235:genetics / Q000378:metabolism*
chemical_list: D003062:Codon; D012329:RNA, Bacterial; D012343:RNA, Transfer
keywords: aminoacylation; codon; modification; protein synthesis; tRNA; translation