title: The history, genotoxicity and carcinogenicity of carbon-based fuels and their emissions: part 4 - alternative fuels.
abstract: Much progress has been made in reducing the pollutants emitted from various combustors (including diesel engines and power plants) by the use of alternative fuels; however, much more progress is needed. Not only must researchers improve fuels and combustors, but also there is a need to improve the toxicology testing and analytical chemistry methods associated with these complex mixtures. Emissions from many alternative carbonaceous fuels are mutagenic and carcinogenic. Depending on their source and derivation, alternative carbonaceous fuels before combustion may or may not be genotoxic; however, in order to know their genotoxicity, appropriate chemical analysis and/or bioassay must be performed. Newly developed fuels and combustors must be tested to determine if they provide a public health advantage over existing technologies - including what tradeoffs can be expected (e.g., decreasing levels of PAHs versus increasing levels of NOx and possibly nitroarenes in ambient air). Another need is to improve exposure estimations which presently are a weak link in doing risk analyses.
authors: LDC Scientific Services, 6012 Brass Lantern Court, Raleigh, NC 27606, United States. Electronic address: ldcss@gmx.com.
authors: Larry D
authors: LD
authors: Claxton
mesh_terms: D000393:Air Pollutants / Q000633:toxicity; D000818:Animals; D056804:Biofuels / Q000633:toxicity*; D015197:Carcinogenicity Tests / Q000379:methods*; D003031:Coal / Q000633:toxicity; D004736:Energy-Generating Resources; D004784:Environmental Monitoring; D006801:Humans; D009369:Neoplasms / Q000139:chemically induced*
chemical_list: D000393:Air Pollutants; D056804:Biofuels; D003031:Coal
keywords: Alternative fuels; Cancer; Carbonaceous fuels; Emissions; Genetic toxicology; Health