title: White matter tracts critical for recognition of sarcasm.
abstract: Failure to recognize sarcasm can lead to important miscommunications. Few previous studies have identified brain lesions associated with impaired recognition of sarcasm. We tested the hypothesis that percent damage to specific white matter tracts, age, and education together predict accuracy in sarcasm recognition. Using multivariable linear regression, with age, education, and percent damage to each of eight white matter tracts as independent variables, and percent accuracy on sarcasm recognition as the dependent variable, we developed a model for predicting sarcasm recognition. Percent damage to the sagittal stratum had the greatest weight and was the only independent predictor of sarcasm recognition.
authors: a Departments of Neurology , Johns Hopkins University , Baltimore , MD 21287 , USA.
authors: Cameron L
authors: CL
authors: Davis
authors: b Radiology , Johns Hopkins University , Baltimore , MD 21287 , USA.
authors: Kenichi
authors: K
authors: Oishi
authors: b Radiology , Johns Hopkins University , Baltimore , MD 21287 , USA.
authors: Andreia V
authors: AV
authors: Faria
authors: b Radiology , Johns Hopkins University , Baltimore , MD 21287 , USA.
authors: John
authors: J
authors: Hsu
authors: a Departments of Neurology , Johns Hopkins University , Baltimore , MD 21287 , USA.
authors: Yessenia
authors: Y
authors: Gomez
authors: b Radiology , Johns Hopkins University , Baltimore , MD 21287 , USA.
authors: Susumu
authors: S
authors: Mori
authors: a Departments of Neurology , Johns Hopkins University , Baltimore , MD 21287 , USA.|c Physical Medicine and Rehabilitation , Johns Hopkins University School of Medicine, Johns Hopkins University , Baltimore , MD 21287 , USA.|d Department of Cognitive Science , Krieger School of Arts and Sciences, Johns Hopkins University , Baltimore , MD 21287 , USA.
authors: Argye E
authors: AE
authors: Hillis
mesh_terms: D002545:Brain Ischemia / Q000473:pathology / Q000523:psychology*; D001931:Brain Mapping; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D021641:Recognition, Psychology / Q000502:physiology*; D012938:Social Perception; D020521:Stroke / Q000473:pathology / Q000523:psychology*; D066127:White Matter / Q000473:pathology*
keywords: attitudinal prosody; cognitive empathy; sagittal stratum; sarcasm; stroke