title: Competing role of bioactive constituents in Moringa oleifera extract and conventional nutrition feed on the performance of Cobb 500 broilers.
abstract: The influence of Moringa oleifera (MO) leaf extract as a dietary supplement on the growth performance and antioxidant parameters was evaluated on broiler meat and the compounds responsible for the corresponding antioxidant activity were identified. 0.5%, 1.0%, and 1.5% w/v of MO leaf aqueous extracts (MOLE) were prepared, and nutritional feed supplemented with 0%, 0.5%, 1.0%, and 1.5% w/w of MO leaf meal (MOLM) extracts were also prepared and analysed for their in vitro antioxidant potential. Furthermore, the treated broiler groups (control (T1) and treatment (T2, T3, and T4)) were evaluated for performance, meat quality, and antioxidant status. The results of this study revealed that, among the broilers fed MOLM, the broilers fed 0.5% w/w MOLM (T2) exhibited enhanced meat quality and antioxidant status (P < 0.05). However, the antioxidant activity of the MOLE is greater than that of the MOLM. The LC-MS/MS analysis of MOLM showed high expression of isoflavones and fatty acids from soy and corn source, which antagonistically inhibit the expression of the flavonoids/phenols in the MO leaves thereby masking its antioxidant effects. Thus, altering the soy and corn gradients in conventional nutrition feed with 0.5% w/w MO leaves supplement would provide an efficient and cost-effective feed supplement.
authors: Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
authors: Govindarajan
authors: G
authors: Karthivashan
authors: Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
authors: Palanisamy
authors: P
authors: Arulselvan
authors: Department of Animal Science, Faculty of Agriculture, Universiti Putra Malaysia, 43400 Selangor, Malaysia.
authors: Abd Razak
authors: AR
authors: Alimon
authors: Laboratory of Natural Products, Institute of Bioscience (IBS), Universiti Putra Malaysia (UPM), 43400 Serdang, Selangor, Malaysia.
authors: Intan
authors: I
authors: Safinar Ismail
authors: Laboratory of Vaccines and Immunotherapeutics, Institute of Bioscience, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia ; Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia.
authors: Sharida
authors: S
authors: Fakurazi
mesh_terms: D000821:Animal Feed; D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D002645:Chickens / Q000254:growth & development*; D019587:Dietary Supplements; D005227:Fatty Acids / Q000737:chemistry / Q000494:pharmacology; D007529:Isoflavones / Q000737:chemistry / Q000494:pharmacology; D008460:Meat; D029588:Moringa oleifera / Q000737:chemistry*; D009752:Nutritional Status / Q000502:physiology; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry
chemical_list: D000975:Antioxidants; D005227:Fatty Acids; D007529:Isoflavones; D010936:Plant Extracts