title: The association of selenium status with thyroid hormones and anthropometric values in dyslipidemic patients.
abstract: BACKGROUND
  Selenium (Se) is an essential micronutrient that performs physiological functions in the metabolism of thyroid hormone and may have an association with anthropometric variables relevant to cardiovascular disease.
  
  
  OBJECTIVE
  To study the associations between Se status, thyroid hormones and anthropometric variables in dyslipidemic patients.
  
  
  METHODS
  Eighty-three patients were assessed in a cross-sectional study. Blood samples were analyzed for Se and thyroid hormones. Anthropometric measurements were taken, and dietary Se intake was investigated.
  
  
  RESULTS
  Mean plasma Se concentrations were low in the patients, at 88.7 ± 16.7 µg/L. Patients with plasma Se ≥ 95 µg/L were found to have a higher body mass index (BMI) (30.74 ± 4.31 vs 27.68 ± 5.63 kg/m2, P = 0.02) and waist-to-height ratio (0.65 ± 0.05 vs 0.59 ± 0.07, P = 0.003) when compared to those with concentrations between 80 and 94 µg/L. Se intake associated positively with T3L/T4L ratio (r = 0.273; P= 0.03), BMI (r= 0.257, P= 0.04) and WC (r= 0.299, P= 0.02).
  
  
  CONCLUSIONS
  The patients with the highest normal plasma Se concentrations were found to have increases in the anthropometric variables we investigated. There is a need for further study in order to elucidate these findings. Furthermore, we found a positive association between Se intake and the most metabolically active form of the thyroid hormones.
authors: Post-graduate Program of Medicine-Cardiology, Federal University of Rio de Janeiro.. glorimar@nutricao.ufrj.br.
authors: Roberta F
authors: RF
authors: Carvalho
authors: Post-graduate Program of Medicine-Cardiology, Federal University of Rio de Janeiro. Department of Nutrition and Dietetics, Josué de Castro Nutrition Institute, Federal University of Rio de Janeiro.. glorimar@nutricao.ufrj.br.
authors: Glorimar
authors: G
authors: Rosa
authors: Post-graduate Program of Medicine-Cardiology, Federal University of Rio de Janeiro.. glorimar@nutricao.ufrj.br.
authors: Grazielle V B
authors: GV
authors: Huguenin
authors: Institute of Public Health Studies, Federal University of Rio de Janeiro.. glorimar@nutricao.ufrj.br.
authors: Ronir R
authors: RR
authors: Luiz
authors: Post-graduate Program of Medicine-Cardiology, Federal University of Rio de Janeiro. Dyslipidemia and Atherosclerosis of Ambulatório, National Institute of Cardiology. Brazil.. glorimar@nutricao.ufrj.br.
authors: Annie S B
authors: AS
authors: Moreira
authors: Post-graduate Program of Medicine-Cardiology, Federal University of Rio de Janeiro.. glorimar@nutricao.ufrj.br.
authors: Glaucia M M
authors: GM
authors: Oliveira
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000886:Anthropometry; D003430:Cross-Sectional Studies; D050171:Dyslipidemias / Q000378:metabolism* / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D012643:Selenium / Q000097:blood*; D013963:Thyroid Hormones / Q000097:blood*
chemical_list: D013963:Thyroid Hormones; D012643:Selenium