title: Chemo-, regio-, and stereoselective Heck-Matsuda arylation of allylic alcohols under mild conditions.
abstract: Heck arylation with allylic alcohol is extremely challenging due to chemo-, regio-, and stereoselective scrambling. Here we report a mild protocol for the alcohol selective β- and α-arylation of allylic and cinnamyl alcohols respectively with aryldiazonium salts. The steric and electronic parameters of the alkene play a prominent role in the regioselectivity.
authors: Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata-700032, West Bengal, India. rjana@iicb.res.in.
authors: Tohasib Yusub
authors: TY
authors: Chaudhari
authors: Asik
authors: A
authors: Hossian
authors: Manash Kumar
authors: MK
authors: Manna
authors: Ranjan
authors: R
authors: Jana
mesh_terms: D015394:Molecular Structure; D020005:Propanols / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D020005:Propanols; C006463:allyl alcohol; C020722:cinnamyl alcohol