title: Vanadium in asymmetric synthesis: emerging concepts in catalyst design and applications.
abstract: In recent years vanadium catalysis has been extended to a range of different and even complementary directions in asymmetric synthesis. Inspired by nature's way to activate both substrate and reagent in many cases, the design of efficient bifunctional and dinuclear vanadium catalysts has been achieved. Furthermore, vanadium catalysis has been an early field in which "hybrid catalysts" have been studied in detail by incorporation of oxovanadium complexes into proteins, thus giving artificial enzymes. In addition, a high compatibility of vanadium with proteins enabled the use of vanadium chemocatalysts for combinations with enzyme catalysis in one-pot, thus leading to dynamic kinetic resolutions. In this contribution, these three concepts of vanadium catalysis opening up new perspectives for asymmetric synthesis are reviewed.
authors: The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibaraki-shi, Osaka 567-0047 (Japan).
authors: Shinobu
authors: S
authors: Takizawa
authors: The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibaraki-shi, Osaka 567-0047 (Japan). harald.groeger@uni-bielefeld.de.|Faculty of Chemistry, Bielefeld University, Universitätsstr. 25, 33615 Bielefeld (Germany). harald.groeger@uni-bielefeld.de.
authors: Harald
authors: H
authors: Gröger
authors: The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibaraki-shi, Osaka 567-0047 (Japan). sasai@sanken.osaka-u.ac.jp.
authors: Hiroaki
authors: H
authors: Sasai
keywords: asymmetric synthesis; enzyme catalysis; metal catalysis; oxidation; vanadium