title: A survey of modulation of gut microbiota by dietary polyphenols.
abstract: Dietary polyphenols present in a broad range of plant foods have been related to beneficial health effects. This review aims to update the current information about the modulation of the gut microbiota by dietary phenolic compounds, from a perspective based on the experimental approaches used. After referring to general aspects of gut microbiota and dietary polyphenols, studies related to this topic are presented according to their experimental design: batch culture fermentations, gastrointestinal simulators, animal model studies, and human intervention studies. In general, studies evidence that dietary polyphenols may contribute to the maintenance of intestinal health by preserving the gut microbial balance through the stimulation of the growth of beneficial bacteria (i.e., lactobacilli and bifidobacteria) and the inhibition of pathogenic bacteria, exerting prebiotic-like effects. Combination of in vitro and in vivo models could help to understand the underlying mechanisms in the polyphenols-microbiota-host triangle and elucidate the implications of polyphenols on human health. From a technological point of view, supplementation with rich-polyphenolic stuffs (phenolic extracts, phenolic-enriched fractions, etc.) could be an effective option to improve health benefits of functional foods such as the case of dairy fermented foods.
authors: Grupo de Investigación en Polifenoles, Unidad de Nutrición y Bromatología, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, 37007 Salamanca, Spain.
authors: Montserrat
authors: M
authors: Dueñas
authors: Grupo de Biotecnología Enológica Aplicada, Instituto de Investigación en Ciencias de la Alimentación (CIAL), CSIC-UAM, Campus de Cantoblanco, C/Nicolás Cabrera 9, 28049 Madrid, Spain.
authors: Irene
authors: I
authors: Muñoz-González
authors: Grupo de Biotecnología Enológica Aplicada, Instituto de Investigación en Ciencias de la Alimentación (CIAL), CSIC-UAM, Campus de Cantoblanco, C/Nicolás Cabrera 9, 28049 Madrid, Spain.
authors: Carolina
authors: C
authors: Cueva
authors: Grupo de Biotecnología Enológica Aplicada, Instituto de Investigación en Ciencias de la Alimentación (CIAL), CSIC-UAM, Campus de Cantoblanco, C/Nicolás Cabrera 9, 28049 Madrid, Spain.
authors: Ana
authors: A
authors: Jiménez-Girón
authors: Grupo de Biotecnología Enológica Aplicada, Instituto de Investigación en Ciencias de la Alimentación (CIAL), CSIC-UAM, Campus de Cantoblanco, C/Nicolás Cabrera 9, 28049 Madrid, Spain.
authors: Fernando
authors: F
authors: Sánchez-Patán
authors: Grupo de Investigación en Polifenoles, Unidad de Nutrición y Bromatología, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, 37007 Salamanca, Spain.
authors: Celestino
authors: C
authors: Santos-Buelga
authors: Grupo de Biotecnología Enológica Aplicada, Instituto de Investigación en Ciencias de la Alimentación (CIAL), CSIC-UAM, Campus de Cantoblanco, C/Nicolás Cabrera 9, 28049 Madrid, Spain.
authors: M Victoria
authors: MV
authors: Moreno-Arribas
authors: Grupo de Biotecnología Enológica Aplicada, Instituto de Investigación en Ciencias de la Alimentación (CIAL), CSIC-UAM, Campus de Cantoblanco, C/Nicolás Cabrera 9, 28049 Madrid, Spain.
authors: Begoña
authors: B
authors: Bartolomé
mesh_terms: D000818:Animals; D004032:Diet; D000069196:Gastrointestinal Microbiome / Q000187:drug effects*; D041981:Gastrointestinal Tract / Q000187:drug effects* / Q000382:microbiology*; D006801:Humans; D064307:Microbiota / Q000187:drug effects*; D059808:Polyphenols / Q000494:pharmacology*; D011795:Surveys and Questionnaires
chemical_list: D059808:Polyphenols