title: Pd-catalyzed enantioselective intramolecular α-arylation of α-substituted cyclic ketones: facile synthesis of functionalized chiral spirobicycles.
abstract: Catalytic synthesis of chiral spirocyclic ketones was accomplished via the Pd-catalyzed intramolecular α-arylation of α-substituted cyclic ketones. The obtained spirocyclic ketone could be converted into a bifunctional organocatalyst.
authors: The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibaraki-shi, Osaka 567-0047, Japan. taki@sanken.osaka-u.ac.jp.
authors: Lulu
authors: L
authors: Fan
authors: Shinobu
authors: S
authors: Takizawa
authors: Yoshiki
authors: Y
authors: Takeuchi
authors: Kazuhiro
authors: K
authors: Takenaka
authors: Hiroaki
authors: H
authors: Sasai
mesh_terms: D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D001643:Bridged Bicyclo Compounds; D007659:Ketones; D009942:Organometallic Compounds; D013141:Spiro Compounds; D010165:Palladium