title: [Analysis of population immunity of residents of Russian Federation regions against seasonal and highly pathogenic strains of influenza virus].
abstract: OBJECTIVE
  Determine the level of antibodies against socially significant types/serotypes of influenza virus in sera of individuals residing in various regions of Russia.
  
  
  METHODS
  1525 samples of blood sera collected in August-December 2013 in 8 regions of Russian Federation were studied in hemagglutination inhibition reaction (HAI) with antigens obtained from A/California/07/09, (H1N1)pdm09, A/Victoria/361/2011(H3N2), B/Brisbane/60/2008 (Victoria line), B/Massachusetts/2/2012 (Yamagata line), A/Commongull/Chany/2006 (H5N1), A/Anhui/01/2013 (H7N9) influenza virus strains.
  
  
  RESULTS
  None of the blood sera samples had significant HAI titers against A/H5 and A/H7 antigens. Of all the 1525 samples, 788 (52%) were positive with A(H1N1)pdm09 antigen; 734 (48%) reacted with A(H3N2) antigen; 1010 (66%) samples were positive with B/Victoria antigen and 602 (39%) samples were positive with B/Yamagata antigen.
  
  
  CONCLUSIONS
  Healthcare institutions should pay attention to the correction of population immunity profile in regions for the reduction of social-economic losses from seasonal influenza epidemics.
authors: T N
authors: TN
authors: Il'icheva
authors: A G
authors: AG
authors: Durymanov
authors: O V
authors: OV
authors: Petrova
authors: A V
authors: AV
authors: Epanchintseva
authors: Iu S
authors: IuS
authors: Chukhrov
authors: Iu A
authors: IuA
authors: Garbuz
authors: I V
authors: IV
authors: Bezgodov
authors: K V
authors: KV
authors: Bulutov
authors: G S
authors: GS
authors: Arkhipov
authors: S S
authors: SS
authors: Samarskiĭ
authors: V B
authors: VB
authors: Ziatdinov
authors: V Iu
authors: VIu
authors: Anan'ev
authors: V N
authors: VN
authors: Mikheev
authors: A B
authors: AB
authors: Ryzhikov
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D000956:Antigens, Viral / Q000276:immunology*; D005260:Female; D006385:Hemagglutination Inhibition Tests; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000276:immunology*; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology / Q000472:pathogenicity; D053122:Influenza A Virus, H3N2 Subtype / Q000276:immunology / Q000472:pathogenicity; D053124:Influenza A Virus, H5N1 Subtype / Q000276:immunology / Q000472:pathogenicity; D064766:Influenza A Virus, H7N9 Subtype / Q000276:immunology / Q000472:pathogenicity; D009981:Influenza B virus / Q000276:immunology / Q000472:pathogenicity; D007251:Influenza, Human / Q000097:blood* / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D012426:Russia / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D019267:Hemagglutinin Glycoproteins, Influenza Virus