title: [Nucleotide receptors and renal function].
abstract: Kidney plays a key role in homeostasis of human body. It has heterogenic structure and is characterized by complicated vascular beds and numbers of sympathetic nerves endings. Nucleotides receptors are involved in the regulation of blood flow, a fundamental process for renal function. Plasma is filtrated in renal glomerulus and activity of nucleotides receptors located on cells of glomerular filter modifies the physi- cochemical properties of filter and affects the filtration process. Electrolytes, water and low molecular weight molecules are reabsorbed from tubular fluid or secreted into fluid in proximal and distal tubules. Glomerular filtration rate and activity of tubular processes are regulated via nucleotides receptors by glomerulotubularbalance and tubuloglomerular feedback. Nucleotides receptors are involved in systemic regulation of blood pressure and carbohydrate metabolism.
authors: Maciej
authors: M
authors: Jankowski
mesh_terms: D001692:Biological Transport; D001794:Blood Pressure / Q000502:physiology; D050260:Carbohydrate Metabolism / Q000502:physiology; D005919:Glomerular Filtration Rate / Q000502:physiology; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D007668:Kidney / Q000502:physiology*; D007684:Kidney Tubules / Q000502:physiology; D009711:Nucleotides / Q000378:metabolism*; D011983:Receptors, Purinergic / Q000378:metabolism*
chemical_list: D009711:Nucleotides; D011983:Receptors, Purinergic