title: Jumping acoustic bubbles on lipid bilayers.
abstract: In the context of sonoporation, we use supported lipid bilayers as a model for biological membranes and investigate the interactions between the bilayer and microbubbles induced by ultrasound. Among the various types of damage caused by bubbles on the surface, our experiments exhibit a singular dynamic interaction process where bubbles are jumping on the bilayer, forming a necklace pattern of alteration on the membrane. This phenomenon was explored with different time and space resolutions and, based on our observations, we propose a model for a microbubble subjected to the combined action of van der Waals, acoustic and hydrodynamic forces. Describing the repeated jumps of the bubble, this model explains the lipid exchanges between the bubble and bilayer.
authors: Institut Lumière Matière, UMR5306 Université Lyon 1-CNRS, Université de Lyon 69622, Villeurbanne cedex, France. jean-paul.rieu@univ-lyon1.fr.
authors: Christelle
authors: C
authors: Der Loughian
authors: Pauline
authors: P
authors: Muleki Seya
authors: Christophe
authors: C
authors: Pirat
authors: Claude
authors: C
authors: Inserra
authors: Jean-Christophe
authors: JC
authors: Béra
authors: Jean-Paul
authors: JP
authors: Rieu
mesh_terms: D008051:Lipid Bilayers / Q000737:chemistry / Q000528:radiation effects*; D016062:Porosity; D013010:Sonication; D000069453:Ultrasonic Waves
chemical_list: D008051:Lipid Bilayers