title: Susceptibility of Helicobacter pylori to Levofloxacin and Rifampicin in Israel.
abstract: The aim of this study was to assess the resistance level of Helicobacter pylori to levofloxacin and rifampicin from samples collected from pediatric and adult Israeli patients from 2012 to 2013. A total of 117 isolate samples of H. pylori were collected between 2012 and 2013. Isolates were cultured from stomach antrum biopsies and identified by the microbiology laboratory. Isolates were considered susceptible to levofloxacin and rifampicin by an Etest. Out of 117 isolates, 105 were found susceptible and 12 resistant to levofloxacin. For rifampicin, 104 isolates were susceptible and 13 were resistant. Study results estimate an alarming resistance rate, which reiterates the need for prudent use of alternative antibiotics to prevent further spread of resistant strains. Therefore, we suggest subjecting cultures from biopsy samples to susceptibility testing for the purpose of identification of strains resistant to levofloxacin and rifampicin among other antibiotic agents. This will allow for successful monitoring of microbial resistance and will assure prudent use of antimicrobial modalities.
authors: 1 Clinical Microbiology Laboratory, Baruch Padeh Medical Center, Poriya, Affiliated with the Faculty of Medicine, Bar Ilan University , Galilee, Israel .
authors: Avi
authors: A
authors: Peretz
authors: 2 Gastrointestinal Unit, Baruch Padeh Medical Center, Poriya, Affiliated with the Faculty of Medicine, Bar Ilan University , Galilee, Israel .
authors: Maya
authors: M
authors: Paritsky
authors: 3 Pharmacy Services, Baruch Padeh Medical Center, Poriya, Affiliated with the Faculty of Medicine, Bar Ilan University , Galilee, Israel .
authors: Eleonora
authors: E
authors: Dinisman-Zavulunov
authors: 1 Clinical Microbiology Laboratory, Baruch Padeh Medical Center, Poriya, Affiliated with the Faculty of Medicine, Bar Ilan University , Galilee, Israel .
authors: Nina
authors: N
authors: Pastukh
authors: 1 Clinical Microbiology Laboratory, Baruch Padeh Medical Center, Poriya, Affiliated with the Faculty of Medicine, Bar Ilan University , Galilee, Israel .
authors: Tatyana
authors: T
authors: Glyatman
authors: 4 Pediatric Gastrointestinal Unit, Baruch Padeh Medical Center, Poriya, Affiliated with the Faculty of Medicine, Bar Ilan University , Galilee, Israel .
authors: Avi
authors: A
authors: On
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002648:Child; D024881:Drug Resistance, Bacterial; D005260:Female; D016481:Helicobacter Infections / Q000382:microbiology; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D007557:Israel / Q000453:epidemiology; D064704:Levofloxacin / Q000494:pharmacology*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011706:Pyloric Antrum / Q000382:microbiology; D012293:Rifampin / Q000494:pharmacology*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D064704:Levofloxacin; D012293:Rifampin