title: Autoimmune polyglandular syndrome type 2: a rare condition in childhood.
abstract: Autoimmune polyglandular syndrome type 2 is defined as the occurrence of Addison's disease concomitantly with autoimmune thyroid disease and/or type 1 diabetes mellitus. An 11-year-old boy with Hashimoto's disease, Addison's disease, celiac disease and Langerhans islet cell autoimmunity is described in this case report. Treatment of an endocrine disease may also trigger the onset of another endocrine disease. This case report underlines the importance of early recognition and treatment of critical endocrine diseases as well as the necessity to investigate pediatric patients with autoimmune diseases for coexisting conditions. Furthermore, the role of psychological stress as an inducer of autoimmunity was also discussed.
authors: Zeynep Kamil Obstetrics and Children Education and Research Hospital, Clinic of Pediatric Endocrinology, İstanbul, Turkey. E-mail: heveskirmizibekmez@yahoo.com.
authors: Heves
authors: H
authors: Kırmızıbekmez
authors: Rahime Gül
authors: RG
authors: Yeşiltepe Mutlu
authors: Nafiye
authors: N
authors: Demirkıran Urgancı
authors: Ayşe
authors: A
authors: Öner
mesh_terms: D000224:Addison Disease / Q000473:pathology* / Q000523:psychology; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000473:pathology* / Q000523:psychology; D050031:Hashimoto Disease / Q000473:pathology* / Q000523:psychology; D006801:Humans; D008297:Male; D016884:Polyendocrinopathies, Autoimmune / Q000473:pathology* / Q000523:psychology; D011379:Prognosis