title: Atypical prefrontal cortical responses to joint/non-joint attention in children with autism spectrum disorder (ASD): A functional near-infrared spectroscopy study.
abstract: Autism spectrum disorder (ASD) is a neuro-developmental disorder, characterized by impairments in one's capacity for joint attention. In this study, functional near-infrared spectroscopy (fNIRS) was applied to study the differences in activation and functional connectivity in the prefrontal cortex between children with autism spectrum disorder (ASD) and typically developing (TD) children. 21 ASD and 20 TD children were recruited to perform joint and non-joint attention tasks. Compared with TD children, children with ASD showed reduced activation and atypical functional connectivity pattern in the prefrontal cortex during joint attention. The atypical development of left prefrontal cortex might play an important role in social cognition defects of children with ASD.
authors: Centre for Optical and Electromagnetic Research, ZJU-SCNU Joint Research Center of Photonics, South China Normal University (SCNU), Guangzhou, 510006, China ; These authors contributed equally.
authors: Huilin
authors: H
authors: Zhu
authors: Centre for Optical and Electromagnetic Research, ZJU-SCNU Joint Research Center of Photonics, South China Normal University (SCNU), Guangzhou, 510006, China ; These authors contributed equally.
authors: Jun
authors: J
authors: Li
authors: Guangzhou Rehabilitation and Research Center for Children with ASD, Guangzhou, 510540, China.
authors: Yuebo
authors: Y
authors: Fan
authors: School of Psychology, South China Normal University (SCNU), Guangzhou, 510631, China.
authors: Xinge
authors: X
authors: Li
authors: Guangzhou Rehabilitation and Research Center for Children with ASD, Guangzhou, 510540, China.
authors: Dan
authors: D
authors: Huang
authors: Centre for Optical and Electromagnetic Research, ZJU-SCNU Joint Research Center of Photonics, South China Normal University (SCNU), Guangzhou, 510006, China ; Department of Electromagnetic Engineering, Royal Institute of Technology, 10044 Stockholm, Sweden.
authors: Sailing
authors: S
authors: He
keywords: (170.2655) Functional monitoring and imaging; (170.3880) Medical and biological imaging; (170.5380) Physiology