title: Early enteral and parenteral nutritional support after hepatectomy in patients with hepatic carcinoma: a systematic review and meta-analysis.
abstract: BACKGROUND
  This study sought to conduct a systematic review providing a comparative analysis of enteral nutrition (EN) and parenteral nutrition (PN) after hepatectomy.
  
  
  METHODS
  PubMed, Embase, and the China National Knowledge Infrastructure databases were searched for publications describing randomized controlled trials that compared early EN and PN after hepatectomy. The time period for this search was from January 1990 to December 2013. In accordance with the inclusion criteria of this study, two researchers independently screened the retrieved literature, extracted data, and assessed methodological quality. A meta-analysis of the included publications was then performed using RevMan 5.2 software.
  
  
  RESULTS
  The meta-analysis results indicated statistically significant differences between the group that received EN and the group that received PN during the early stages after hepatectomy with respect to average total bilirubin and alanine aminotransferase levels after nutrition, pre-albumin levels, incidence of diarrhea and abdominal bloating, time to flatus, and average cost of nutrition. To varying degrees, better results were observed in the EN group than in the PN group for these metrics.
  
  
  CONCLUSIONS
  During the early stages after hepatectomy, EN has obvious advantages relative to PN; thus, EN merits more widespread promotion and application in this clinical context.
authors: Department of Respiratory Medicine, Haiyang People's Hospital, Haiyang, People's Republic of China.
authors: Lin-Ben
authors: LB
authors: Gao
authors: Department of Oncology, Shandong Province Tumor Hospital, Jinnan, People's Republic of China.
authors: He
authors: H
authors: Tian
authors: Department of Respiratory Medicine, Provincial Hospital Affiliated to Shandong University, Jinnan, People's Republic of China.
authors: Xing-Guang
authors: XG
authors: Wang
authors: Department of Emergency, Haiyang People's Hospital, Haiyang, People's Republic of China.
authors: Xiao-Fei
authors: XF
authors: Yu
authors: Department of Oncology, Shandong Province Tumor Hospital, Jinnan, People's Republic of China.
authors: Yan
authors: Y
authors: Guan
authors: Department of Nuclear Radiology, Shandong Province Tumor Hospital, Jinnan, People's Republic of China.
authors: Ming-Lu
authors: ML
authors: Chen
authors: Department of Gastroenterology, Haiyang People's Hospital, Haiyang, People's Republic of China.
authors: Jian
authors: J
authors: Zhang
keywords: enteral nutrition; hepatectomy; meta-analysis; parenteral nutrition; systematic review