title: Discrimination and content analysis of fritillaria using near infrared spectroscopy.
abstract: Fritillaria is a traditional Chinese herbal medicine which can be used to moisten the lungs. The objective of this study is to develop simple, accurate, and solvent-free methods to discriminate and quantify Fritillaria herbs from seven different origins. Near infrared spectroscopy (NIRS) methods are established for the rapid discrimination of seven different Fritillaria samples and quantitative analysis of their total alkaloids. The scaling to first range method and the partial least square (PLS) method are used for the establishment of qualitative and quantitative analysis models. As a result of evaluation for the qualitative NIR model, the selectivity values between groups are always above 2, and the mistaken judgment rate of fifteen samples in prediction sets was zero. This means that the NIR model can be used to distinguish different species of Fritillaria herbs. The established quantitative NIR model can accurately predict the content of total alkaloids from Fritillaria samples.
authors: State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China ; School of Pharmaceutical Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors: Yu
authors: Y
authors: Meng
authors: State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China ; School of Pharmaceutical Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors: Shisheng
authors: S
authors: Wang
authors: State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China ; School of Pharmaceutical Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors: Rui
authors: R
authors: Cai
authors: State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China ; School of Pharmaceutical Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors: Bohai
authors: B
authors: Jiang
authors: State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China ; School of Pharmaceutical Science and Technology, Dalian University of Technology, Dalian 116024, China.
authors: Weijie
authors: W
authors: Zhao