title: [Massive panniculectomy and bilateral subtotal mastectomy in a case of calciphylaxis: A case report and up date].
abstract: Calciphylaxis or calcific arteriolopathy is a rare, life-threatening obstructive pathology of the small cutaneous and subcutaneous vessels. It mainly affects patients with chronic renal failure but it also has been described in patients with normal renal function. The principal risks factors apart from renal failure and phosphocalcic metabolism imbalance are: the female sex, obesity, peripheral vascular disease, diabetes and oral anti-coagulation. We present a very rare case of abdominal, mammarian and upper thighs calciphylaxis in a patient with normal renal function. She presented a severe obesity with a recent important loss of weight and had been treated by oral anticoagulants for a long time. She benefited of a multidisciplinary approach with dermatologists, plastic surgeons and anesthesists permitting a recovery in fourteen weeks. Multidisciplinary approach is necessary but the place of the surgery is not well defined. We report a case in which early and wide surgical approach permitted to obtain a favourable evolution of the pathology. Then, we propose a therapeutic strategy after review of the literature.
authors: Service de chirurgie plastique reconstructrice et esthétique, hôpital Roger-Salengro, CHRU, 59037 Lille, France. Electronic address: yasmine.bennis@orange.fr.
authors: Y
authors: Y
authors: Bennis
authors: Clinique dermatologique, hôpital Claude-Huriez, CHRU, 59037 Lille, France; Faculté de médecine Henri Warembourg, université de Lille, 59045 Lille, France.
authors: C
authors: C
authors: Becquart
authors: Service de chirurgie plastique reconstructrice et esthétique, hôpital Roger-Salengro, CHRU, 59037 Lille, France.
authors: N
authors: N
authors: Aljudaibi
authors: Chirurgie générale et vasculaire, hôpital Claude-Huriez, CHRU, 59037 Lille, France; Faculté de médecine Henri Warembourg, université de Lille, 59045 Lille, France.
authors: P
authors: P
authors: Patenotre
authors: Service de chirurgie plastique reconstructrice et esthétique, hôpital Roger-Salengro, CHRU, 59037 Lille, France; Faculté de médecine Henri Warembourg, université de Lille, 59045 Lille, France.
authors: P
authors: P
authors: Guerreschi
authors: Clinique dermatologique, hôpital Claude-Huriez, CHRU, 59037 Lille, France; Faculté de médecine Henri Warembourg, université de Lille, 59045 Lille, France.
authors: E
authors: E
authors: Delaporte
authors: Service de chirurgie plastique reconstructrice et esthétique, hôpital Roger-Salengro, CHRU, 59037 Lille, France; Faculté de médecine Henri Warembourg, université de Lille, 59045 Lille, France.
authors: V
authors: V
authors: Duquennoy-Martinot
mesh_terms: D061645:Abdominoplasty; D000925:Anticoagulants / Q000627:therapeutic use; D002115:Calciphylaxis / Q000601:surgery*; D005260:Female; D006801:Humans; D008408:Mastectomy; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications; D010630:Phenindione / Q000031:analogs & derivatives / Q000627:therapeutic use; D054556:Venous Thromboembolism / Q000150:complications / Q000188:drug therapy
chemical_list: D000925:Anticoagulants; D010630:Phenindione; C017673:fluindione
keywords: Calciphylaxie; Calciphylaxis; Dermolipectomie abdominale; Mastectomie subtotale; Panniculectomy; Subtotal mastectomy