title: ADAMTS13, lucky to have a hydrophobic pocket.
abstract: In this issue of Blood, de Groot et al identify a hydrophobic pocket in the Cys-rich domain of ADAMTS13 that appears to interact with the hydrophobic pocket in the central A2 domain of von Willebrand factor (VWF) for its proteolysis.
authors: UNIVERSITY OF ALABAMA AT BIRMINGHAM.
authors: X Long
authors: XL
authors: Zheng
mesh_terms: D051722:ADAM Proteins / Q000502:physiology*; D000071120:ADAMTS13 Protein; D006801:Humans; D014841:von Willebrand Factor / Q000737:chemistry*
chemical_list: D014841:von Willebrand Factor; D051722:ADAM Proteins; D000071120:ADAMTS13 Protein; C099604:ADAMTS13 protein, human