title: [Perspectives of selective laboratory screening in children with joint pathology].
abstract: The article highlights the problematic issues of the laboratory diagnostic possibilities in children with joint pathology with moden tests (anti-cyclic citrullinated peptide antibodies and antibodies to mutated citrullinated vimentin). The expediency and effectiveness of the proposed laboratory tests is justified for improvement of the early differential diagnosis, joint pathology treatment optimization, and discuss the prospect of selective laboratory screening in families burdened by rheumatic diseases genealogy.
authors: T A
authors: TA
authors: Pychkova
authors: L I
authors: LI
authors: Taloverova
mesh_terms: D000293:Adolescent; D001172:Arthritis, Rheumatoid / Q000175:diagnosis*; D001323:Autoantibodies / Q000032:analysis / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D019411:Clinical Laboratory Techniques / Q000379:methods*; D003937:Diagnosis, Differential; D018450:Disease Progression; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000175:diagnosis; D008297:Male; D008403:Mass Screening / Q000379:methods*; D014746:Vimentin / Q000276:immunology
chemical_list: D001323:Autoantibodies; D014746:Vimentin