title: [The PATENT-1 and CHEST-1 studies].
authors: Gavino
authors: G
authors: Casu
authors: Laura
authors: L
authors: Scelsi
authors: Marco
authors: M
authors: Morsolini
authors: Andrea M
authors: AM
authors: D'Armini
mesh_terms: D017326:Clinical Trials, Phase III as Topic; D018450:Disease Progression; D004417:Dyspnea / Q000209:etiology / Q000517:prevention & control; D023381:Endpoint Determination; D005080:Exercise Test; D006162:Guanylate Cyclase / Q000378:metabolism; D006801:Humans; D006976:Hypertension, Pulmonary / Q000097:blood / Q000145:classification / Q000150:complications / Q000188:drug therapy*; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010446:Peptide Fragments / Q000097:blood; D011720:Pyrazoles / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D011743:Pyrimidines / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D014655:Vascular Resistance / Q000187:drug effects; D016138:Walking; D014944:World Health Organization
chemical_list: D010446:Peptide Fragments; D011720:Pyrazoles; D011743:Pyrimidines; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain; D006162:Guanylate Cyclase; C542595:riociguat