title: Sterile endophthalmitis after intravitreal ocriplasmin injection: report of a single case.
abstract: OBJECTIVE
  To report a case of presumed sterile endophthalmitis after intravitreal ocriplasmin injection.
  
  
  METHODS
  Observational case report. Review of clinical examination, ocular imaging, and published literature.
  
  
  RESULTS
  A 67-year-old woman with early cataracts presented with decreased vision in the left eye related to vitreomacular adhesion. She was treated with intravitreal ocriplasmin injection and developed a severe anterior chamber inflammatory reaction in less than 24 hours after the injection. Inflammation responded completely to topical steroids alone, without topical or intravitreal antibiotics.
  
  
  CONCLUSIONS
  Patients treated with intravitreal ocriplasmin may develop an acute inflammatory reaction, which can be severe.
authors: Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland.
authors: Ian C
authors: IC
authors: Han
authors: Adrienne W
authors: AW
authors: Scott
mesh_terms: D000368:Aged; D009877:Endophthalmitis / Q000139:chemically induced*; D005260:Female; D005341:Fibrinolysin / Q000009:adverse effects*; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D006801:Humans; D058449:Intravitreal Injections / Q000009:adverse effects; D010446:Peptide Fragments / Q000009:adverse effects*
chemical_list: D005343:Fibrinolytic Agents; D010446:Peptide Fragments; C054561:microplasmin; D005341:Fibrinolysin