title: Line-field parallel swept source MHz OCT for structural and functional retinal imaging.
abstract: We demonstrate three-dimensional structural and functional retinal imaging with line-field parallel swept source imaging (LPSI) at acquisition speeds of up to 1 MHz equivalent A-scan rate with sensitivity better than 93.5 dB at a central wavelength of 840 nm. The results demonstrate competitive sensitivity, speed, image contrast and penetration depth when compared to conventional point scanning OCT. LPSI allows high-speed retinal imaging of function and morphology with commercially available components. We further demonstrate a method that mitigates the effect of the lateral Gaussian intensity distribution across the line focus and demonstrate and discuss the feasibility of high-speed optical angiography for visualization of the retinal microcirculation.
authors: Center for Med. Physics and Biomed. Engineering, Medical University Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria ; Christian Doppler Laboratory for Laser Development and their Application to Medicine and Biology, Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Austria.
authors: Daniel J
authors: DJ
authors: Fechtig
authors: Center for Med. Physics and Biomed. Engineering, Medical University Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
authors: Branislav
authors: B
authors: Grajciar
authors: Carl Zeiss Meditec, Inc., 5160 Hacienda Drive, Dublin, CA 94568, USA.
authors: Tilman
authors: T
authors: Schmoll
authors: Center for Med. Physics and Biomed. Engineering, Medical University Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
authors: Cedric
authors: C
authors: Blatter
authors: Center for Med. Physics and Biomed. Engineering, Medical University Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.
authors: Rene M
authors: RM
authors: Werkmeister
authors: Center for Med. Physics and Biomed. Engineering, Medical University Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria ; Christian Doppler Laboratory for Laser Development and their Application to Medicine and Biology, Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Austria.
authors: Wolfgang
authors: W
authors: Drexler
authors: Center for Med. Physics and Biomed. Engineering, Medical University Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria ; Christian Doppler Laboratory for Laser Development and their Application to Medicine and Biology, Center for Medical Physics and Biomedical Engineering, Medical University Vienna, Austria.
authors: Rainer A
authors: RA
authors: Leitgeb
keywords: (110.4500) Optical coherence tomography; (170.0110) Imaging systems; (170.3880) Medical and biological imaging; (170.4460) Ophthalmic optics and devices