title: The effect of hydroalcoholic extract of P. crispum on sperm parameters, testis tissue and serum nitric oxide levels in mice.
abstract: BACKGROUND
  Sperm dysfunction is one of the main causes of male infertility. Petroselinum crispum (P. crispum) is a member of umbelliferae family that contains different vitamins and minerals and has numerous therapeutic properties. The aim of this study was to evaluate P. crispum effect on sperm parameters, testis tissue and serum nitric oxid levels in mice.
  
  
  METHODS
  Hydroalcoholic extract of P. crispum was prepared and administered intraperitoneally (0,100, 150 and 200 mg/kg) to 40 mice, which were divided into four groups (n = 10), one control group and three experimental groups, for 14 consequent days. The sperm parameter such as motility, sperm count, morphology, and seminiferous tubules diameter, and weight of prostate and testis, and serum nitric oxide levels were analyzed.
  
  
  RESULTS
  P. crispum administration (100, 150 and 200 mg/kg) significantly increased mean percentage of sperm motility, testis and prostate weight and serum nitric oxide compared to the control group (P < 0.05). However, no significant effect was reported for different doses of P. crispum extract on sperm parameters.
  
  
  CONCLUSIONS
  Administrating hydroalcoholic extract of P. crispum has positive effects on some reproductive parameters.
authors: Fertility and Infertility Research Center, Kermanshah, Iran.
authors: Cyrus
authors: C
authors: Jalili
authors: Fertility and Infertility Research Center, Kermanshah, Iran.
authors: Mohammad Reza
authors: MR
authors: Salahshoor
authors: Kermanshah University of Medical Sciences, Kermanshah, Iran.
authors: Tahere
authors: T
authors: Naderi
keywords: Mice; Petroselinum crispum; nitric oxide; sperm parameters; testis