title: Do recognizable lifetime eating disorder phenotypes naturally occur in a culturally asian population? A combined latent profile and taxometric approach.
abstract: BACKGROUND
  We examined whether empirically derived eating disorder (ED) categories in Hong Kong Chinese patients (N = 454) would be consistent with recognizable lifetime ED phenotypes derived from latent structure models of European and American samples.
  
  
  METHODS
  We performed latent profile analysis (LPA) using indicator variables from data collected during routine assessment, and then applied taxometric analysis to determine whether latent classes were qualitatively versus quantitatively distinct.
  
  
  RESULTS
  Latent profile analysis identified four classes: (i) binge/purge (47%); (ii) non-fat-phobic low-weight (34%); (iii) fat-phobic low-weight (12%); and (iv) overweight disordered eating (6%). Taxometric analysis identified qualitative (categorical) distinctions between the binge/purge and non-fat-phobic low-weight classes, and also between the fat-phobic and non-fat-phobic low-weight classes. Distinctions between the fat-phobic low-weight and binge/purge classes were indeterminate.
  
  
  CONCLUSIONS
  Empirically derived categories in Hong Kong showed recognizable correspondence with recognizable lifetime ED phenotypes. Although taxometric findings support two distinct classes of low weight EDs, LPA findings also support heterogeneity among non-fat-phobic individuals.
authors: Department of Psychiatry, Harvard Medical School, MA, USA; Eating Disorders Clinical and Research Program, Massachusetts General Hospital, MA, USA.
authors: Jennifer J
authors: JJ
authors: Thomas
authors: Kamryn T
authors: KT
authors: Eddy
authors: John
authors: J
authors: Ruscio
authors: King Lam
authors: KL
authors: Ng
authors: Kristen E
authors: KE
authors: Casale
authors: Anne E
authors: AE
authors: Becker
authors: Sing
authors: S
authors: Lee
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000145:classification / Q000175:diagnosis; D044466:Asian People / Q000235:genetics*; D056912:Binge-Eating Disorder / Q000145:classification / Q000175:diagnosis / Q000523:psychology; D001835:Body Weight; D003469:Culture; D005163:Factor Analysis, Statistical; D001068:Feeding and Eating Disorders / Q000145:classification* / Q000175:diagnosis / Q000208:ethnology / Q000235:genetics* / Q000523:psychology; D005260:Female; D006723:Hong Kong; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D013851:Thinness / Q000523:psychology
keywords: DSM-5; anorexia nervosa; fat phobia; latent profile analysis; taxometric analysis