title: Orbital tumor revealing a systemic sarcoidosis.
abstract: Ocular involvement is seen in approximately 25% of patients with sarcoidosis. Uveitis is the most common ocular manifestation, but sarcoidosis may involve any part of the eye. Orbital manifestations of sarcoidosis are uncommon with few series in the literature. A 65-year-old woman presented with redness of the right eye and painless, unilateral eyelid swelling. Orbital scanning revealed mass infiltrating the soft tissue of the inferior right orbital quadrant. Biopsy results showed nodular, noncaseating granulomas consistent with sarcoidosis. The complete systemic workup revealed systemic manifestations of sarcoidosis at the time of examination with hilar and mediastinal lymphadenopathies noted on CT scan. The orbital surgical treatment was followed by systemic prednisone therapy with good response. Although rare, orbital sarcoidosis must be considered in the evaluation of orbital tumors in elderly patients. A search for systemic findings should be undertaken and appropriate therapy should be instituted.
authors: Department of Pathology, Salah Azaeiz Institute, Bab Saadoun, 1006 Tunis, Tunisia. fatma.khanchel@gmail.com.
authors: Samia
authors: S
authors: Hannanachi Sassi
authors: Department of Pathology, Salah Azaeiz Institute, Bab Saadoun, 1006 Tunis, Tunisia. fatma.khanchel@gmail.com.
authors: Rim
authors: R
authors: Dhouib
authors: Department of Pathology, Salah Azaeiz Institute, Bab Saadoun, 1006 Tunis, Tunisia. fatma.khanchel@gmail.com.
authors: Fatma
authors: F
authors: Kanchal
authors: Department of Pathology, Salah Azaeiz Institute, Bab Saadoun, 1006 Tunis, Tunisia. fatma.khanchel@gmail.com.
authors: Raoudha
authors: R
authors: Doghri
authors: Department of Pathology, Salah Azaeiz Institute, Bab Saadoun, 1006 Tunis, Tunisia. fatma.khanchel@gmail.com.
authors: Nadia
authors: N
authors: Boujelbene
authors: Department of Ophthalmology, Hedi Rais Institute of Ophthalmology, Bab Saadoun, 1006 Tunis, Tunisia. fatma.khanchel@gmail.com.
authors: Hedi
authors: H
authors: Bouguila
authors: Department of Pathology, Salah Azaeiz Institute, Bab Saadoun, 1006 Tunis, Tunisia. fatma.khanchel@gmail.com.
authors: Karima
authors: K
authors: Mrad
mesh_terms: D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012507:Sarcoidosis / Q000150:complications / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed