title: Multifocal choroiditis and panuveitis presenting with progressive equatorial linear streaks: evolution of Schlaegel lines documented with multimodal imaging.
abstract: OBJECTIVE
  To describe the progressive, peripheral linear streaks of the equatorial retina, known as Schlaegel lines, in multifocal choroiditis and panuveitis (MCP).
  
  
  METHODS
  A case report of a 13-year-old girl with MCP showed progression of retinal linear streaks. Extensive systemic and ophthalmologic investigations were performed.
  
  
  RESULTS
  Linear streaks in MCP showed progression before the institution of immunomodulatory treatment. Infrared imaging showed hyperreflectivity of the lesions with surrounding hyporeflectivity. Optical coherence tomography showed elevated and irregular hyperreflectivity of the retinal pigment epithelium and choroidal hyperreflectivity. These findings, including the clinical progression before immunomodulatory therapy and negative systemic evaluation for infectious entities, are consistent with MCP.
  
  
  CONCLUSIONS
  Patients with linear streaks in the setting of atypical MCP can progress and should be treated with adequate systemic corticosteroids and immunomodulatory agents. This case is unique in that it shows the evolution of Schlaegel lines using a multimodal imaging approach. Multimodal imaging can provide ancillary evidence of disease activity.
authors: *Francis I. Proctor Foundation, University of California, San Francisco, San Francisco, California; †Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; and ‡Retinal Medical Group, Sacramento, California.
authors: Thanapong
authors: T
authors: Somkijrungroj
authors: Joel A
authors: JA
authors: Pearlman
authors: John A
authors: JA
authors: Gonzales
mesh_terms: D000293:Adolescent; D002829:Choroid / Q000473:pathology; D002833:Choroiditis / Q000473:pathology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D000080364:Multifocal Choroiditis; D064847:Multimodal Imaging; D015864:Panuveitis / Q000473:pathology*; D055213:Retinal Pigment Epithelium / Q000473:pathology