title: The value of high-resolution MRI technique in patients with rectal carcinoma: pre-operative assessment of mesorectal fascia involvement, circumferential resection margin and local staging.
abstract: BACKGROUND
  The purpose of the study was to identify the accuracy of high-resolution MRI in the pre-operative assessment of mesorectal fascia involvement, circumfrential resection margin (CRM) and local staging in patients with rectal carcinoma.
  
  
  METHODS
  The study included 56 patients: 32 male and 24 female. All patients underwent high-resolution MRI and had confirmed histopathological diagnosis of rectal cancer located within 15 cm from the anal verge, followed by surgery. MRI findings were compared with pathological and surgical results.
  
  
  RESULTS
  The overall accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of MRI-based T-staging were 92.8, 88.8%, 96.5%, 96%, and 90.3%, respectively. The accuracy, sensitivity, specificity, PPV, and NPV of MRI-based assessment of CRM were 94.6%, 84.6%, 97.6%, 91.4, and 94.6%, respectively. The accuracy, sensitivity, specificity, PPV, and NPV of MRI-based N-staging were 82.1%, 75%, 67.3%, 60%, and 86.1%, respectively.
  
  
  CONCLUSIONS
  Preoperative high-resolution rectal MRI is accurate in predicting tumor stage and CRM involvement. MRI is a precise diagnostic tool to select patients who may benefit from neo-adjuvant therapy and to avoid overtreatment in those patients who can proceed directly to surgery.
authors: Department of Diagnostic Imaging and Nuclear Medicine, Zagazig University, Zagazig, Egypt.
authors: Ahmed Mohamed
authors: AM
authors: Algebally
authors: Department of Diagnostic Imaging and Nuclear Medicine, Zagazig University, Zagazig, Egypt.
authors: Nesreen
authors: N
authors: Mohey
authors: Department of Clinical Imaging, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
authors: Wojciech
authors: W
authors: Szmigielski
authors: Department of Radiology, Alazhar University, Cairo, Egypt.
authors: Reda Ramadan Hussein
authors: RR
authors: Yousef
authors: Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar.
authors: Samah
authors: S
authors: Kohla
keywords: Magnetic Resonance Imaging; Neoplasm Staging; Rectal Neoplasms