title: Shorter epilepsy duration is associated with better seizure outcome in temporal lobe epilepsy surgery.
abstract: OBJECTIVE
  To investigate the influence of patient's age and seizure onset on surgical outcome of temporal lobe epilepsy (TLE).
  
  
  METHODS
  A retrospective observational investigation performed from a cohort of patients from 2000 to 2012.
  
  
  RESULTS
  A total of 229 patients were included. One-hundred and eleven of 179 patients (62%) were classified as Engel I in the group with < 50 years old, whereas 33 of 50 (66%) in the group with ≥ 50 years old group (p = 0.82). From those Engel I, 88 (61%) reported epilepsy duration inferior to 10 years and 56 (39%) superior to 10 years (p < 0.01). From the total of patients not seizure free, 36 (42%) reported epilepsy duration inferior to 10 years and 49 (58%) superior to 10 years (p < 0.01).
  
  
  CONCLUSIONS
  Patients with shorter duration of epilepsy before surgery had better postoperative seizure control than patients with longer duration of seizures.
authors: Departamento de Ciências Neurológicas, Hospital Base, Faculdade de Medicina de São José do Rio Preto, Sao José do Rio Preto, SP, Brazil.
authors: Lucas Crociati
authors: LC
authors: Meguins
authors: Departamento de Ciências Neurológicas, Hospital Base, Faculdade de Medicina de São José do Rio Preto, Sao José do Rio Preto, SP, Brazil.
authors: Rodrigo Antônio Rocha da Cruz
authors: RA
authors: Adry
authors: Departamento de Ciências Neurológicas, Hospital Base, Faculdade de Medicina de São José do Rio Preto, Sao José do Rio Preto, SP, Brazil.
authors: Sebastião Carlos da
authors: SC
authors: Silva-Junior
authors: Departamento de Psiquiatria e Psicologia Médica, Faculdade de Medicina de São José do Rio Preto, Sao José do Rio Preto, SP, Brazil.
authors: Gerardo Maria de
authors: GM
authors: Araújo Filho
authors: Departamento de Ciências Neurológicas, Hospital Base, Faculdade de Medicina de São José do Rio Preto, Sao José do Rio Preto, SP, Brazil.
authors: Lúcia Helena Neves
authors: LH
authors: Marques
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011184:Postoperative Period; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012640:Seizures / Q000503:physiopathology / Q000517:prevention & control*; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult