title: Objective Assessment of the Rheological Muscle Property in the Treatment of Fibromyalgia.
abstract: Fibromyalgia (FM), clinical condition characterized by several signs and symptoms such as widespread pain, trigger point, morning stiffness and extreme tiredness for scarce hours of sleep, is linked to several changes in several brain neurotransmitters, particularly serotonin and norepinephrine. Consequently, the Neural Vegetative System works more and so it generates an exaggerated muscular contraction, sweating and constriction of blood vessels. The aim of our study was to treat a selected group of female patients suffering from FM with duloxetine with physiotherapy. We used two clinical scales (VAS and FIQ) and an objective evaluation such as myometric. The analysis of the data Myoton used during any inspection showed a statistically significant reduction in the values of muscle tone in each district analyzed. This finding was also confirmed by the patients themselves who have experienced a significant welfare and less muscle tension in different locations, as evidenced by data obtained from the clinical scales used by us. In addition, our patients were thought to be satisfied with the improvements not only subjective, but also with the objective witnessed myometry, making them a share of the study and feeling constantly monitored for treatment aimed at a real reduction in muscle stiffness. In conclusion, our study demonstrates combined treatment duloxetine- physiotherapy effectively reduces a symptom often disabling and particularly troublesome in patients with FM as the exaggerated muscle contraction.
authors: Neuroscience and Sense Organs Department, Physical Medicine and Rehabilitation - University of Bari, Bari, Italy. ricmarv81@hotmail.it.
authors: Riccardo
authors: R
authors: Marvulli
authors: Giancarlo
authors: G
authors: Ianieri
authors: Lucia
authors: L
authors: Mastromauro
authors: Ersilia
authors: E
authors: Romanelli
authors: Laura
authors: L
authors: Barulli
authors: Pierpaolo
authors: P
authors: Chiumarulo
authors: Gianfranco
authors: G
authors: Megna
authors: Marisa
authors: M
authors: Megna
mesh_terms: D000328:Adult; D000700:Analgesics / Q000627:therapeutic use; D000068736:Duloxetine Hydrochloride / Q000627:therapeutic use*; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D005356:Fibromyalgia / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000187:drug effects / Q000502:physiology*; D012212:Rheology / Q000379:methods*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D000700:Analgesics; D000068736:Duloxetine Hydrochloride