title: Open retromuscular mesh repair of complex incisional hernia: predictors of wound events and recurrence.
abstract: BACKGROUND
  Mesh repair of incisional hernias has been consistently shown to diminish recurrence rates after repair, with an increased risk of infectious complications. We present a consecutive series of elective, retrorectus mesh repairs of the abdominal wall and attempt to determine predictors of wound events and recurrence.
  
  
  METHODS
  A retrospective review was performed to include elective, retromuscular mesh repairs of complex incisional hernias from August 2006 to August 2013. Demographics, operative details, and postoperative events including wound events, surgical site infections (SSI), and recurrences were recorded.
  
  
  RESULTS
  Over the 7-year period, 255 retromuscular mesh repairs of midline incisional defects were performed. Median age of the patients was 58 years, with an average BMI of 32.2 kg/m(2). Average size of the fascial defect was 181.4 cm(2), with recurrent defects making up 48% of repairs. Wound events occurred in 37.7% of cases; SSIs occurred in 19.6% of cases. Recurrence rate was 16.9%, with mean time to recurrence of 19.2 months. With respect to mesh type, recurrences were 16.2% with synthetic, 17.1% for bioabsorbable, and 25% for biologic mesh. When evaluating polypropylene meshes, recurrence was more likely with lightweight mesh (22.9%) vs midweight mesh (10.6%) (p = 0.045). Predictors of SSI included history of mesh infection (odds ratio [OR] 4.8, 95% CI 1.9 to 12.1; p < 0.001) and recurrent repairs (OR 2.5, 95% CI 1.1 to 5.8; p < 0.05). The only predictor of recurrence was the presence of an SSI (OR 3.1, 95% CI 1.5 to 6.3; p < 0.01).
  
  
  CONCLUSIONS
  Wound events are common after open mesh repairs of complex incisional hernias. Previous mesh infections and recurrent repairs increase the likelihood of an SSI, which significantly increases the risk of recurrence. Recurrences after retrorectus mesh repairs are significantly higher with lightweight compared with mid-weight meshes.
authors: Department of Surgery, Greenville Health System, Greenville, SC. Electronic address: wcobb@ghs.org.
authors: William S
authors: WS
authors: Cobb
authors: Department of Surgery, Greenville Health System, Greenville, SC.
authors: Jeremy A
authors: JA
authors: Warren
authors: Department of Surgery, Greenville Health System, Greenville, SC.
authors: Joseph A
authors: JA
authors: Ewing
authors: Department of Surgery, Greenville Health System, Greenville, SC.
authors: Alex
authors: A
authors: Burnikel
authors: Department of Surgery, Greenville Health System, Greenville, SC.
authors: Miller
authors: M
authors: Merchant
authors: Department of Surgery, Greenville Health System, Greenville, SC.
authors: Alfredo M
authors: AM
authors: Carbonell
mesh_terms: D034861:Abdominal Wall / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006555:Hernia, Ventral / Q000601:surgery*; D059685:Herniorrhaphy / Q000379:methods*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D013022:South Carolina / Q000453:epidemiology; D013526:Surgical Mesh; D013530:Surgical Wound Infection / Q000453:epidemiology*; D055815:Young Adult