title: Percutaneous transhepatic cholangiography and intraductal radiofrequency ablation combined with biliary stent placement for malignant biliary obstruction.
abstract: OBJECTIVE
  To determine the safety and feasibility of percutaneous transhepatic cholangiography (PTC) and intraductal radiofrequency (RF) ablation combined with biliary stent placement for malignant biliary obstruction.
  
  
  METHODS
  Data from patients with unresectable malignant biliary obstruction who underwent PTC, intraductal RF ablation, and biliary stent placement (n = 12) or PTC and biliary stent placement only (control group; n = 14) were reviewed. Postoperative complications, jaundice remission, and stent patency were assessed.
  
  
  RESULTS
  All procedures were successful. No severe complications (eg, biliary bleeding, perforation) occurred. Two experimental group patients developed cholangitis, which resolved with conservative treatment. The 1-week jaundice remission and 3-month stent patency rates were similar in both groups, but the 6-month stent patency rate was higher in the experimental group (P < .05). In the experimental group, one death occurred as a result of gastrointestinal hemorrhage (unrelated to stent placement) by 3 months, and there were two cases of recurrent jaundice by 6 months. The latter two patients underwent repeat PTC, ablation, and stent placement. In the control group, one death occurred as a result of hepatic failure caused by progressive jaundice at 3 months, and another death resulted from disseminated intravascular coagulation caused by jaundice recurrence at 138 days after stent placement. In addition, seven patients developed jaundice recurrence (50-151 d after stent placement). PTC and repeat stent placement were performed in these patients.
  
  
  CONCLUSIONS
  Percutaneous transhepatic cholangiography and intraductal RF ablation combined with biliary stent placement for malignant biliary obstruction is safe and feasible and effectively prolongs stent patency time.
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: Teng-Fei
authors: TF
authors: Li
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: Guo-Hao
authors: GH
authors: Huang
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: Zhen
authors: Z
authors: Li
authors: College of Public Health, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: Chang-Fu
authors: CF
authors: Hao
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: Jian-Zhuang
authors: JZ
authors: Ren
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: Xu-Hua
authors: XH
authors: Duan
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: Kai
authors: K
authors: Zhang
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: Chen
authors: C
authors: Chen
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China. Electronic address: hanxinwei2006@163.com.
authors: Xin-Wei
authors: XW
authors: Han
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: De-Chao
authors: DC
authors: Jiao
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: Meng-Fan
authors: MF
authors: Zhang
authors: Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China; Interventional Institute, Zhengzhou University, Zhengzhou, People's Republic of China.
authors: Yan-Li
authors: YL
authors: Wang
mesh_terms: D001650:Bile Duct Neoplasms / Q000150:complications*; D017115:Catheter Ablation; D002758:Cholangiography / Q000379:methods*; D002779:Cholestasis / Q000000981:diagnostic imaging* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D015607:Stents; D016896:Treatment Outcome