title: Gastrointestinal bleeding after continuous-flow left ventricular device implantation: review of pathophysiology and management.
abstract: Gastrointestinal bleeding is one of the most common complications in patients with continuous-flow left ventricular assist devices. Though the exact pathophysiology is still unclear, continuous-flow physiology, acquired Von Willebrand disease, and formation of arteriovenous malformations in the gastrointestinal tract are implicated. An individualized plan of endoscopic therapy and anticoagulation management is required when caring for these patients.
authors: Houston Methodist Hospital, Houston, Texas.
authors: Ashrith
authors: A
authors: Guha
authors: Houston Methodist Hospital, Houston, Texas.
authors: Carrie L
authors: CL
authors: Eshelbrenner
authors: Houston Methodist Hospital, Houston, Texas.
authors: David M
authors: DM
authors: Richards
authors: Houston Methodist Hospital, Houston, Texas.
authors: Howard P
authors: HP
authors: Monsour
mesh_terms: D003131:Combined Modality Therapy; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy*; D006333:Heart Failure / Q000175:diagnosis / Q000601:surgery*; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006489:Hemostatic Techniques; D006801:Humans; D008297:Male; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000401:mortality / Q000503:physiopathology* / Q000628:therapy*; D011379:Prognosis; D018570:Risk Assessment; D012720:Severity of Illness Index; D015996:Survival Rate
keywords: LVAD risk factors; gastrointestinal bleeding; heart assist device