title: MARK-AGE standard operating procedures (SOPs): A successful effort.
abstract: Within the MARK-AGE project, a population study (3337 subjects) was conducted to identify a set of biomarkers of ageing which, as a combination of parameters with appropriate weighting, would measure biological age better than any single marker. The MARK-AGE project involves 14 European countries and a total of 26 research centres. In such a study, standard operating procedures (SOPs) are an essential task, which are binding for all MARK-AGE Beneficiaries. The SOPs cover all aspects of subject's recruitment, collection, shipment and distribution of biological samples (blood and its components, buccal mucosa cells or BMC and urine) as well as the anthropometric measurements and questionnaires.
authors: Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany. Electronic address: maria.moreno-villanueva@uni-konstanz.de.
authors: María
authors: M
authors: Moreno-Villanueva
authors: DIMES-Department of Experimental, Diagnostic and Specialty Medicine, CIG-Interdepartmentall Centre "L.Galvani", Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.
authors: Miriam
authors: M
authors: Capri
authors: Institute of Nutritional Medicine, University of Hohenheim, 70599 Stuttgart, Germany.
authors: Nicolle
authors: N
authors: Breusing
authors: BioTeSys GmbH, 73728 Esslingen, Germany.
authors: Anne
authors: A
authors: Siepelmeyer
authors: DIMES-Department of Experimental, Diagnostic and Specialty Medicine, CIG-Interdepartmentall Centre "L.Galvani", Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.
authors: Federica
authors: F
authors: Sevini
authors: National Association "Famiglie di Persone con Disabilita Affettiva e/o Relazionale" (ANFFAS) Onlus, Macerata, Italy.
authors: Alessandro
authors: A
authors: Ghezzo
authors: Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands.
authors: Anton J M
authors: AJ
authors: de Craen
authors: School of Medicine, University of Tampere, 33014 Tampere, Finland.
authors: Antti
authors: A
authors: Hervonen
authors: School of Medicine, University of Tampere, 33014 Tampere, Finland.
authors: Mikko
authors: M
authors: Hurme
authors: BioTeSys GmbH, 73728 Esslingen, Germany.
authors: Christiane
authors: C
authors: Schön
authors: Institute of Nutritional Medicine, University of Hohenheim, 70599 Stuttgart, Germany; German Institute of Human Nutrition, 14558 Nuthetal, Germany.
authors: Tilman
authors: T
authors: Grune
authors: DIMES-Department of Experimental, Diagnostic and Specialty Medicine, CIG-Interdepartmentall Centre "L.Galvani", Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.
authors: Claudio
authors: C
authors: Franceschi
authors: Molecular Toxicology Group, Department of Biology, University of Konstanz, 78457 Konstanz, Germany.
authors: Alexander
authors: A
authors: Bürkle
mesh_terms: D000375:Aging / Q000097:blood* / Q000652:urine*; D015415:Biomarkers / Q000097:blood / Q000652:urine; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D015415:Biomarkers
keywords: Biobank; Human studies; Standard operating procedures