title: Use of microRNAs as Anti-Atherosclerosis.
abstract: MicroRNAs are a class of non-coding RNA molecules that have been reported to play a crucial role in cell signaling via post-transcriptional regulation of gene expression. There is increasing evidence showing that this class of RNA is involved in the pathogenesis of cardiovascular diseases, including atherosclerosis. More recently, it has been demonstrated that microRNAs can function to protect against the development of atherosclerosis. The primary goal of this review is to discuss the discovery, mechanism, and therapeutic use of microRNA molecules as atheroprotective agents.
authors: Hui
authors: H
authors: Wang
authors: Shutong
authors: S
authors: Shen
authors: Qinkao
authors: Q
authors: Xuan
authors: Xiuzhi
authors: X
authors: Wang
authors: Xinli
authors: X
authors: Li
authors: Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China. xiangqingkong_nj@163.com.
authors: Xiangqing
authors: X
authors: Kong
mesh_terms: D000818:Animals; D050197:Atherosclerosis / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D042783:Endothelial Cells / Q000473:pathology; D006801:Humans; D052439:Lipid Metabolism Disorders / Q000235:genetics / Q000628:therapy; D035683:MicroRNAs / Q000235:genetics*; D032389:Myocytes, Smooth Muscle / Q000473:pathology
chemical_list: D035683:MicroRNAs