title: BODIPY-based probes for the fluorescence imaging of biomolecules in living cells.
abstract: Fluorescence imaging techniques have been widely used to visualize biological molecules and phenomena. In particular, several studies on the development of small-molecule fluorescent probes have been carried out, because their fluorescence properties can be easily tuned by synthetic chemical modification. For this reason, various fluorescent probes have been developed for targeting biological components, such as proteins, peptides, amino acids, and ions, to the interior and exterior of cells. In this review, we cover advances in the development of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY)-based fluorescent probes for biological studies over the past decade.
authors: Immunology Frontier Research Center (IFReC), Osaka University, Suita, Osaka 565-0871, Japan. kkikuchi@mls.eng.osaka-u.ac.jp.
authors: Toshiyuki
authors: T
authors: Kowada
authors: Hiroki
authors: H
authors: Maeda
authors: Kazuya
authors: K
authors: Kikuchi
mesh_terms: D000818:Animals; D001896:Boron Compounds; D002460:Cell Line; D003584:Cytological Techniques; D005456:Fluorescent Dyes; D006801:Humans; D051379:Mice; D061848:Optical Imaging / Q000379:methods*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D005456:Fluorescent Dyes