title: Nocardiosis presenting as a lung mass in a kidney transplant recipient.
abstract: Nocardiosis is a potentially life-threatening disease in renal transplant recipients. It is an uncommon infection with high lethality if left untreated. We report a case of a 67 year-old kidney transplant recipient who developed pulmonary nocardiosis and presented with pleural effusion along with an underlying lung mass, which was successfully treated with trimethoprim-sulphamethoxazole in conjunction with a reduction in immunosuppressive therapy. Five months later, graft function remains stable with complete regression of radiological abnormalities and absence of symptoms. Nocardiosis should be suspected in the presence of pulmonary symptoms in a transplant patient with unusual radiological presentation.
authors: Central Northern Adelaide Renal and Transplant Service, Adelaide, South Australia, Australia.
authors: Harris
authors: H
authors: Hakim
authors: Nitesh N
authors: NN
authors: Rao
authors: Randall J
authors: RJ
authors: Faull
authors: Patrick T
authors: PT
authors: Coates
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D009617:Nocardia Infections / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D009894:Opportunistic Infections / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D010996:Pleural Effusion / Q000382:microbiology; D012141:Respiratory Tract Infections / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D003074:Solitary Pulmonary Nodule / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
keywords: nocardia; renal; transplant