title: Intrapericardial injections using a novel technique.
abstract: Intrapericardial injections have been proposed as a means to specifically treat diseases of the myocardium, pericardium, and coronary vasculature. The pericardial space is potential drug reservoir, allowing sustained delivery of drug to the target tissue. In this study we have demonstrated a novel method for pericardial delivery in the mouse.
authors: V V
authors: VV
authors: Holobotovskyy
authors: L F
authors: LF
authors: Arnolda
authors: D J
authors: DJ
authors: McKitrick
mesh_terms: D000818:Animals; D001645:Biguanides / Q000008:administration & dosage; D001794:Blood Pressure / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D007267:Injections / Q000379:methods*; D051379:Mice; D023421:Models, Animal; D010496:Pericardium; D010656:Phenylephrine / Q000008:administration & dosage
chemical_list: D001645:Biguanides; D010656:Phenylephrine; C008846:phenyl biguanide