title: The uterine choriocarcinoma in postmenopausal women: specificities of diagnosis and treatment.
abstract: Choriocarcinoma is a gestational trophoblastic tumor that mainly affects women of childbearing age. Cases of choriocarcinoma in postmenopausal women are exceptional. Through an observation and literature review, we propose to study the specific diagnosis and treatment features of this tumor in menopausal women. We report the observation of a pure uterine choriocarcinoma, which occurred in post-menopause. The diagnosis was made on the analysis of surgical specimens confirmed by measurement of hCG. Chemotherapy was started after a total hysterectomy and bilateral salpingo-oophorectomy first. The improvement was dramatic after 3 courses of chemotherapy and the patient is in complete remission after five years of monitoring. The primitive forms of pure choriocarcinoma in postmenopausal women are exceptional. Their etiology is poorly understood and their treatment based on chemotherapy.
authors: Department of Gynecology Obstetrics, University Hospital Farhat Hached Sousse, Tunisia.
authors: Ons
authors: O
authors: Kaabia
authors: Department of Gynecology Obstetrics, University Hospital Farhat Hached Sousse, Tunisia.
authors: Sawsen
authors: S
authors: Meddeb
authors: Department of Gynecology Obstetrics, University Hospital Farhat Hached Sousse, Tunisia.
authors: Mohamed Salah
authors: MS
authors: Rhim
authors: Department of Gynecology Obstetrics, University Hospital Farhat Hached Sousse, Tunisia.
authors: Mohamed
authors: M
authors: Bibi
authors: Department of Gynecology Obstetrics, University Hospital Farhat Hached Sousse, Tunisia.
authors: Hedi
authors: H
authors: Khairi
mesh_terms: D002822:Choriocarcinoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods; D008875:Middle Aged; D010052:Ovariectomy / Q000379:methods; D017698:Postmenopause; D058994:Salpingectomy / Q000379:methods; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy
keywords: Uterine choriocarcinoma; gestational trophoblastic tumor; post menopause