title: Increased Neutrophil to Lymphocyte Ratio in Patients With Resistant Hypertension.
abstract: Resistant hypertension (RHT) is an important disease that causes an increase in cardiovascular risk, yet its etiology remains unclear. The authors aimed to investigate neutrophil/lymphocyte ratio (NLR) as an inflammation marker in patients with RHT. A total of 150 patients were included in the study and grouped according to their office and ambulatory blood pressure measurements. They were classified as having normotension (NT), controlled hypertension (CHT), or RHT. The RHT group had a significantly higher NLR than the CHT group (P=.03), and NLRs of both hypertension groups were significantly higher than those in the NT group (P<.001, for both). NLR and neutrophil count were found to be independent correlates for RHT in multivariate analysis (P<.001). NLR and neutrophil count are increased in RHT patients than both CHT and NT patients. This finding, which is defined for the first time in patients with RHT, may imply the importance of inflammation in blood pressure control.
authors: Department of Cardiology, Okmeydanı Training and Research Hospital, Istanbul, Turkey.
authors: Erdal
authors: E
authors: Belen
authors: Department of Cardiology, Kahramanmaras Necip Fazıl City Hospital, Kahramanmaras, Turkey.
authors: Aylin
authors: A
authors: Sungur
authors: Department of Cardiology, Kahramanmaras Necip Fazıl City Hospital, Kahramanmaras, Turkey.
authors: Mustafa Azmi
authors: MA
authors: Sungur
authors: Department of Cardiology, Ordu Training and Research Hospital, Ordu, Turkey.
authors: Güney
authors: G
authors: Erdoğan
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000097:blood; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000503:physiopathology; D007249:Inflammation / Q000097:blood; D007958:Leukocyte Count; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology*; D012307:Risk Factors
chemical_list: D015415:Biomarkers