title: The dangers of iodine-based contrasts in an elderly patient with thyroid disease.
abstract: Iodine-based contrast agents are widely used in angiographic and other radiological procedures. Clinicians are familiar with many of the potential adverse events from contrast agents including allergic reactions and contrast-induced nephropathy. This case describes a lesser known adverse event: 'contrast-induced thyrotoxicosis' and its implications on the presentation and management of a patient with severe coronary artery disease. The management of this case was difficult and required a long inpatient admission with use of prednisolone, propylthiouracil and planned treatment with radioiodine to control the thyrotoxicosis, as well as the use of several rate-limiting agents and antianginal medications to control atrial fibrillation and prevent further episodes of angina.
authors: Department of Cardiology, City Hospitals Sunderland, Sunderland, Tyne and Wear, UK.
authors: David
authors: D
authors: Ledingham
authors: Department of Endocrinology, City Hospitals Sunderland, Sunderland, Tyne and Wear, UK.
authors: Peter
authors: P
authors: Carey
authors: Department of Cardiology, City Hospitals Sunderland, Sunderland, Tyne and Wear, UK.
authors: Shahid
authors: S
authors: Junejo
mesh_terms: D000368:Aged; D013956:Antithyroid Agents / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000000981:diagnostic imaging* / Q000188:drug therapy; D002231:Carbimazole / Q000627:therapeutic use; D003287:Contrast Media / Q000009:adverse effects*; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects; D008297:Male; D011877:Radionuclide Imaging; D013959:Thyroid Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy; D013971:Thyrotoxicosis / Q000139:chemically induced*; D016896:Treatment Outcome
chemical_list: D013956:Antithyroid Agents; D003287:Contrast Media; D007457:Iodine Radioisotopes; D002231:Carbimazole