title: Walking and psychomotor speed in the elderly: concordance, correlates and prediction of death.
abstract: OBJECTIVE
  To investigate the concordance between walking (WS) and psychomotor speed (PS), correlates of both tasks, and their capacity to predict mortality in the elderly.
  
  
  METHODS
  Seven-year cohort study of 1,365 community-dwelling subjects aged 65-95 years, participating in the Bordeaux sample of the Three City Study, a French prospective cohort designed to evaluate the risk of cognitive decline attributable to vascular risk factors.
  
  
  METHODS
  Participants completed a battery of cognitive assessments including time to complete Trail Making Test A used as a PS measure, and a measure of WS. Socio-demographic determinants, co-morbidities, functional and cognitive evaluation, and incident mortality were taken into account.
  
  
  RESULTS
  Mean age was 75.7 (SD ± 5.4) years. WS and TMT-A speed have very low concordance (kappa coefficient=.05). The correlates of each measure were different: mostly clinical co-morbidities for WS, and mostly cognition and function for TMT-A speed. However, TMT-A speed and WS are both independent predictors of death after seven years of follow-up.
  
  
  CONCLUSIONS
  WS and TMT-A speed could be considered as two different dimensions of age-related slowness, but both performances were associated with higher risk of mortality.
authors: Jean-François Dartigues, MD, PhD. Centre de Recherche INSERM, U897, 146 rue Léo Saignat, 33076 Bordeaux cedex, France, E-mail: jean-francois.dartigues@isped.u-bordeaux2.fr.
authors: M
authors: M
authors: Tabue-Teguo
authors: M
authors: M
authors: Le Goff
authors: J A
authors: JA
authors: Avila-Funes
authors: E
authors: E
authors: Frison
authors: C
authors: C
authors: Helmer
authors: C
authors: C
authors: Féart
authors: H
authors: H
authors: Amieva
authors: J F
authors: JF
authors: Dartigues
mesh_terms: D000054:Acceleration; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition / Q000502:physiology; D003072:Cognition Disorders / Q000453:epidemiology* / Q000401:mortality; D015897:Comorbidity; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D009026:Mortality; D011446:Prospective Studies; D011597:Psychomotor Performance / Q000502:physiology*; D012111:Residence Characteristics; D012307:Risk Factors; D013997:Time Factors; D014145:Trail Making Test; D016138:Walking / Q000502:physiology*