title: Severe Pediatric Head Injury During the Iraq and Afghanistan Conflicts.
abstract: BACKGROUND
  Much has been written about injuries sustained by US and coalition soldiers during the Global War on Terrorism campaigns. However, injuries to civilians, including children, have been less well documented.
  
  
  OBJECTIVE
  To describe the epidemiologic features and outcomes associated with isolated severe head injury in children during Operations Enduring Freedom and Iraqi Freedom (OEF and OIF).
  
  
  METHODS
  A retrospective review of children (<18 years old) in the Joint Theater Trauma Registry with isolated head injury (defined as an Abbreviated Injury Score Severity Code >3) and treated at a US combat support hospital in Iraq or Afghanistan (2004-2012). The primary outcome was in-hospital mortality.
  
  
  RESULTS
  We identified 647 children with severe isolated head injuries: 337 from OEF, 268 from OIF, and 42 nontheater specific. Most were boys (76%; median age = 8 years). Penetrating injuries were most common (60.6%). Overall, 330 (51%) children underwent a craniotomy/craniectomy; 156 (24.1%) succumbed to their injuries. Admission Glasgow Coma Score was predictive of survival among the entire cohort and each of the individual conflicts. Male sex also significantly increased the odds of survival for the entire group and OEF, but not for OIF. Closed-head injury improved the predictive ability of our model but did not reach statistical significance as an independent factor.
  
  
  CONCLUSIONS
  This is the largest study of combat-related isolated head injuries in children. Admission Glasgow Coma Score and male sex were found to be predictive of survival. Assets to comprehensively care for the pediatric patient should be established early in future conflicts.
authors: *Semmes-Murphey Neurologic & Spine Institute, Memphis, Tennessee; ‡Department of Neurosurgery, University of Tennessee Health Sciences Center, Memphis, Tennessee; §Department of Neurosurgery, Mercy Hospital and Clinic, Springfield, Missouri; ¶Department of Clinical Pharmacy, University of Tennessee Health Sciences Center, Memphis, Tennessee; ‖Wilford Hall Medical Center, Lackland Air Force Base, Texas.
authors: Paul
authors: P
authors: Klimo
authors: Brian T
authors: BT
authors: Ragel
authors: G Morgan
authors: GM
authors: Jones
authors: Randall
authors: R
authors: McCafferty
mesh_terms: D000293:Adolescent; D055826:Afghan Campaign 2001-; D000346:Afghanistan; D002648:Child; D002675:Child, Preschool; D006259:Craniocerebral Trauma / Q000453:epidemiology*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007493:Iraq; D054542:Iraq War, 2003-2011; D008297:Male; D012189:Retrospective Studies; D000067398:War-Related Injuries / Q000453:epidemiology*