title: An integrated model-based software for FUS in moving abdominal organs.
abstract: Focused ultrasound surgery (FUS) is a non-invasive method for tissue ablation that has the potential for complete and controlled local tumour destruction with minimal side effects. The treatment of abdominal organs such as the liver, however, requires particular technological support in order to enable a safe, efficient and effective treatment. As FUS is applied from outside the patient's body, suitable imaging methods, such as magnetic resonance imaging or diagnostic ultrasound, are needed to guide and track the procedure. To facilitate an efficient FUS procedure in the liver, the organ motion during breathing and the partial occlusion by the rib cage need to be taken into account in real time, demanding a continuous patient-specific adaptation of the treatment configuration. Modelling the patient's respiratory motion and combining this with tracking data improves the accuracy of motion predictions. Modelling and simulation of the FUS effects within the body allows the use of treatment planning and has the potential to be used within therapy to increase knowledge about the patient status. This article describes integrated model-based software for patient-specific modelling and prediction for FUS treatments of moving abdominal organs.
authors: Fraunhofer Institute for Medical Image Computing MEVIS , Bremen , Germany .
authors: Michael
authors: M
authors: Schwenke
authors: Jan
authors: J
authors: Strehlow
authors: Sabrina
authors: S
authors: Haase
authors: Juergen
authors: J
authors: Jenne
authors: Christine
authors: C
authors: Tanner
authors: Thomas
authors: T
authors: Langø
authors: Arjo J
authors: AJ
authors: Loeve
authors: Ioannis
authors: I
authors: Karakitsios
authors: Xu
authors: X
authors: Xiao
authors: Yoav
authors: Y
authors: Levy
authors: Giora
authors: G
authors: Sat
authors: Mario
authors: M
authors: Bezzi
authors: Stefan
authors: S
authors: Braunewell
authors: Matthias
authors: M
authors: Guenther
authors: Andreas
authors: A
authors: Melzer
authors: Tobias
authors: T
authors: Preusser
mesh_terms: D000005:Abdomen / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D016896:Treatment Outcome; D059708:Ultrasonic Surgical Procedures / Q000379:methods*; D014464:Ultrasonic Therapy / Q000379:methods*
keywords: Clinical trials-thermal ablation; high-intensity focused ultrasound; modelling; thermal ablation