title: Synthesis of planar chiral [2.2]paracyclophane-based bisoxazoline ligands bearing no central chirality and application to Cu-catalyzed asymmetric O-H insertion reaction.
abstract: C2-symmetric planar chiral [2.2]paracyclophane-based bisoxazoline ligands, characterized by the inserted benzene spacer, which has a sterically demanding substituent, were synthesized and it was shown that up to 80% ee was obtained for the Cu-catalyzed O-H insertion reaction of α-diazo esters without the aid of the central chirality.
authors: Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya 468-8503, Japan. skitagak@meijo-u.ac.jp.
authors: Shinji
authors: S
authors: Kitagaki
authors: Kenta
authors: K
authors: Sugisaka
authors: Chisato
authors: C
authors: Mukai
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D011083:Polycyclic Compounds / Q000737:chemistry*
chemical_list: D008024:Ligands; D010080:Oxazoles; D011083:Polycyclic Compounds; C515344:(2.2)paracyclophane; D003300:Copper