title: Resolution of Small Bowel Follicular Lymphoma With Treatment of Concomitant Hepatitis B.
abstract: We report a case of small bowel follicular lymphoma regression with hepatitis B virus treatment. Our patient underwent surveillance colonoscopy that showed profound nodularity in the terminal ileum that was consistent with non-Hodgkin's lymphoma (NHL) on biopsy. Upon further testing the patient was found to be infected with hepatitis B virus. We decided to treat hepatitis B first to prevent its reactivation if the patient underwent therapy for NHL and with the thought that NHL can be stimulated by immunological response to antigens. Our patient was started on Entecavir, and fortunately the NHL regressed with no recurrence on follow-up endoscopies and biopsies.
authors: *Yale New Haven Hospital †Department of Digestive Diseases and Internal Medicine, Yale School of Medicine, New Haven, CT.
authors: Muhammad S
authors: MS
authors: Mansoor
authors: David M
authors: DM
authors: Wolfsohn
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D003113:Colonoscopy; D006147:Guanine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006509:Hepatitis B / Q000150:complications / Q000188:drug therapy* / Q000821:virology; D006515:Hepatitis B virus; D006801:Humans; D007414:Intestinal Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000821:virology; D007421:Intestine, Small / Q000821:virology; D008224:Lymphoma, Follicular / Q000150:complications / Q000188:drug therapy* / Q000821:virology; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000821:virology
chemical_list: D000998:Antiviral Agents; C413685:entecavir; D006147:Guanine