title: Chemotherapy of lung cancer: A global perspective of the role of ifosfamide.
abstract: The oxazaphosphorine cytostatic ifosfamide (IFO) has been successfully integrated in the treatment of various hematological and solid tumors. The purpose of this review is to summarize the evidence for its use in lung cancer starting from basic data of preclinical studies followed by a global summary of the phase III and seminal phase II clinical studies. Global in double respect: first covering both the small cell as well as the non-small cell indications, and, second tracing those studies performed in Europe and the United States as well as those from Asian countries.
authors: Department of Oncology, Shanghai Pulmonary Hospital, Affiliated to Tongji University School of Medicine, Shanghai, China ;
authors: Caicun
authors: C
authors: Zhou
authors: Department of Surgery, Interdisciplinary Thoracic Oncology, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany.
authors: Christian
authors: C
authors: Manegold
keywords: Lung cancer; chemotherapy; ifosfamide