title: From Concept to Bedside: What Pediatricians Should Know about Synthesis of Clinical Practice Guidelines?
abstract: Clinical Practice guidelines (CPGs) have emerged as a potentially effective intervention in delivering a high quality, consistent, safe and evidence-based health care. CPGs can either be developed by de novo synthesis or by adaptation of existing guidelines formed in another organization. Guideline recommendations are formulated based on strength of the evidence, validity, clinical relevance and patient values. Support of the organization leadership, role modeling of senior staff and involvement of stakeholders is a key to the success of implementation of guidelines. This article aims to enhance a practicing pediatrician's understanding of how guidelines are developed, disseminated, and potentially utilized.
authors: Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
authors: Sarar
authors: S
authors: Mohamed
keywords: Adaptation; Clinical Practice Guidelines; Development; Implementation; Synthesis