title: Prevalence of hepatitis B and hepatitis C infections and their relationship to injectable drug use in a cohort of Sri Lankan prison inmates.
abstract: BACKGROUND
  Prisoners are considered to be at high risk for Hepatitis B (HBV) and Hepatitis C (HCV) virus infections. This is attributed to intravenous drug use and high-risk sexual behaviour. There are no published studies on HBV and HCV among prison inmates or injecting drug users in Sri Lanka.
  
  
  OBJECTIVE
  To determine prevalence of HBV and HCV infections, and their relationship to injectable drug use among Sri Lankan prisoners.
  
  
  METHODS
  We investigated 393 (median age 42 years (range 16 to 93); 82% males) randomly selected inmates of Mahara and Welikada prisons.
  
  
  RESULTS
  Though 167 (42.5%) admitted drug abuse, only 17 (4.3%) had ever used intravenous drugs. Twelve (70.6%) of them reported sharing needles. One inmate was positive for HBsAg but was negative for HBV-DNA. Twenty seven (6.9%) were positive for anti-HCV antibodies, of whom only 2 (0.5%) were positive for HCV-RNA. None of the injecting drug users were positive for HBV-DNA or HCV-RNA.
  
  
  CONCLUSIONS
  The prevalence of HBV and HCV infections as well as injecting drug use was very low among this cohort of Sri Lankan prison inmates.
authors: Departments of Medicine, Faculty of Medicine, University of Kelaniya, Sri Lanka. maduniln@yahoo.co.uk.
authors: M A
authors: MA
authors: Niriella
authors: A
authors: A
authors: Hapangama
authors: H P D P
authors: HP
authors: Luke
authors: A
authors: A
authors: Pathmeswaran
authors: K A L A
authors: KA
authors: Kuruppuarachchi
authors: H J
authors: HJ
authors: de Silva
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004279:DNA, Viral / Q000097:blood; D005260:Female; D006509:Hepatitis B / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D006526:Hepatitis C / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D018937:Hepatitis C Antibodies / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011329:Prisoners / Q000706:statistics & numerical data*; D011330:Prisons; D012367:RNA, Viral / Q000097:blood; D016036:Seroepidemiologic Studies; D013188:Sri Lanka / Q000453:epidemiology; D015819:Substance Abuse, Intravenous / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D004279:DNA, Viral; D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies; D012367:RNA, Viral