title: Early Surgical Site Infection Following Tissue Expander Breast Reconstruction with or without Acellular Dermal Matrix: National Benchmarking Using National Surgical Quality Improvement Program.
abstract: BACKGROUND
  Surgical site infections (SSIs) result in significant patient morbidity following immediate tissue expander breast reconstruction (ITEBR). This study determined a single institution's 30-day SSI rate and benchmarked it against that among national institutions participating in the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP).
  
  
  METHODS
  Women who underwent ITEBR with/without acellular dermal matrix (ADM) were identified using the ACS-NSQIP database between 2005 and 2011. Patient characteristics associated with the 30-day SSI rate were determined, and differences in rates between our institution and the national database were assessed.
  
  
  RESULTS
  12,163 patients underwent ITEBR, including 263 at our institution. SSIs occurred in 416 (3.4%) patients nationwide excluding our institution, with lower rates observed at our institution (1.9%). Nationwide, SSIs were significantly more common in ITEBR patients with ADM (4.5%) compared to non-ADM patients (3.2%, P=0.005), and this trend was observed at our institution (2.1% vs. 1.6%, P=1.00). A multivariable analysis of all institutions identified age ≥50 years (odds ratio [OR], 1.4; confidence interval [CI], 1.1-1.7), body mass index ≥30 kg/m(2) vs. <25 kg/m(2) (OR, 3.4; CI, 2.6-4.5), and operative time >4.25 hours (OR, 1.9; CI, 1.5-2.4) as risk factors for SSIs. Our institutional SSI rate was lower than the nationwide rate (OR, 0.4; CI, 0.2-1.1), although this difference was not statistically significant (P=0.07).
  
  
  CONCLUSIONS
  The 30-day SSI rate at our institution in patients who underwent ITEBR was lower than the nation. SSIs occurred more frequently in procedures involving ADM both nationally and at our institution.
authors: Division of Plastic Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA.
authors: Sebastian
authors: S
authors: Winocour
authors: Division of Plastic Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA.
authors: Jorys
authors: J
authors: Martinez-Jorge
authors: Department of Health Sciences Research, Rochester, NM, USA.
authors: Elizabeth
authors: E
authors: Habermann
authors: Department of Health Sciences Research, Rochester, NM, USA.
authors: Kristine
authors: K
authors: Thomsen
authors: Division of Plastic Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA.
authors: Valerie
authors: V
authors: Lemaine
keywords: Acellular dermis; Benchmarking; Breast implantation; Surgical wound infection