title: Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma.
abstract: OBJECTIVE
  The outcome for patients with metastatic or recurrent sarcoma remains poor. Adoptive therapy with tumor-directed T cells is an attractive therapeutic option but has never been evaluated in sarcoma.
  
  
  METHODS
  We conducted a phase I/II clinical study in which patients with recurrent/refractory human epidermal growth factor receptor 2 (HER2) -positive sarcoma received escalating doses (1 × 10(4)/m(2) to 1 × 10(8)/m(2)) of T cells expressing an HER2-specific chimeric antigen receptor with a CD28.ζ signaling domain (HER2-CAR T cells).
  
  
  RESULTS
  We enrolled 19 patients with HER2-positive tumors (16 osteosarcomas, one Ewing sarcoma, one primitive neuroectodermal tumor, and one desmoplastic small round cell tumor). HER2-CAR T-cell infusions were well tolerated with no dose-limiting toxicity. At dose level 3 (1 × 10(5)/m(2)) and above, we detected HER2-CAR T cells 3 hours after infusion by quantitative polymerase chain reaction in 14 of 16 patients. HER2-CAR T cells persisted for at least 6 weeks in seven of the nine evaluable patients who received greater than 1 × 10(6)/m(2) HER2-CAR T cells (P = .005). HER2-CAR T cells were detected at tumor sites of two of two patients examined. Of 17 evaluable patients, four had stable disease for 12 weeks to 14 months. Three of these patients had their tumor removed, with one showing ≥ 90% necrosis. The median overall survival of all 19 infused patients was 10.3 months (range, 5.1 to 29.1 months).
  
  
  CONCLUSIONS
  This first evaluation of the safety and efficacy of HER2-CAR T cells in patients with cancer shows the cells can persist for 6 weeks without evident toxicities, setting the stage for studies that combine HER2-CAR T cells with other immunomodulatory approaches to enhance their expansion and persistence.
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Nabil
authors: N
authors: Ahmed
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Vita S
authors: VS
authors: Brawley
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Meenakshi
authors: M
authors: Hegde
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Catherine
authors: C
authors: Robertson
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Alexia
authors: A
authors: Ghazi
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Claudia
authors: C
authors: Gerken
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Enli
authors: E
authors: Liu
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Olga
authors: O
authors: Dakhova
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Aidin
authors: A
authors: Ashoori
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Amanda
authors: A
authors: Corder
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Tara
authors: T
authors: Gray
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Meng-Fen
authors: MF
authors: Wu
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Hao
authors: H
authors: Liu
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: John
authors: J
authors: Hicks
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Nino
authors: N
authors: Rainusso
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Gianpietro
authors: G
authors: Dotti
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Zhuyong
authors: Z
authors: Mei
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Bambi
authors: B
authors: Grilley
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Adrian
authors: A
authors: Gee
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Cliona M
authors: CM
authors: Rooney
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Malcolm K
authors: MK
authors: Brenner
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Helen E
authors: HE
authors: Heslop
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Winfried S
authors: WS
authors: Wels
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Lisa L
authors: LL
authors: Wang
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
authors: Peter
authors: P
authors: Anderson
authors: Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, and Stephen Gottschalk, Center for Cell and Gene Therapy, Texas Children's Hospital, Baylor College of Medicine, Houston Methodist Hospital; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, John Hicks, Nino Rainusso, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine; Nabil Ahmed, Vita S. Brawley, Meenakshi Hegde, Catherine Robertson, Alexia Ghazi, Claudia Gerken, Enli Liu, Olga Dakhova, Aidin Ashoori, Amanda Corder, Tara Gray, Meng-Fen Wu, Hao Liu, John Hicks, Nino Rainusso, Gianpietro Dotti, Zhuyong Mei, Bambi Grilley, Adrian Gee, Cliona M. Rooney, Malcolm K. Brenner, Helen E. Heslop, Lisa L. Wang, and Stephen Gottschalk, Baylor College of Medicine; Peter Anderson, The University of Texas MD Anderson Cancer Center, Houston, TX; Peter Anderson, Levine Children's Hospital, Levine Cancer Institute, Carolinas Healthcare System, Charlotte NC; and Winfried S. Wels, Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany. smgottsc@txch.org.
authors: Stephen
authors: S
authors: Gottschalk
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000378:metabolism / Q000628:therapy*; D002648:Child; D005260:Female; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D053208:Kaplan-Meier Estimate; D008279:Magnetic Resonance Imaging; D008297:Male; D020714:Maximum Tolerated Dose; D009362:Neoplasm Metastasis; D017599:Neuroectodermal Tumors / Q000378:metabolism / Q000628:therapy; D012516:Osteosarcoma / Q000378:metabolism / Q000628:therapy; D049268:Positron-Emission Tomography; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000235:genetics / Q000378:metabolism*; D011948:Receptors, Antigen, T-Cell / Q000737:chemistry; D012008:Recurrence; D012509:Sarcoma / Q000378:metabolism / Q000628:therapy*; D012512:Sarcoma, Ewing / Q000378:metabolism / Q000628:therapy; D013601:T-Lymphocytes / Q000276:immunology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D018719:Erb-b2 Receptor Tyrosine Kinases; D011948:Receptors, Antigen, T-Cell; C508053:ERBB2 protein, human