title: Chitosan nanofibers fabricated by combined ultrasonic atomization and freeze casting.
abstract: Aligned chitosan nanofibers exhibiting diameters smaller than 100 nm were easily prepared by combining ultrasonic atomization with freeze casting. A major advantage of this approach is the use of distilled water as main solvent. Scanning electron microscopy demonstrated that fiber diameter and morphology mainly depended on the atomizing tools, freezing temperature, and chitosan solution viscosity. Minimum diameter and uniform orientation were achieved using an electric flosser as an atomizing tool, liquid nitrogen as a coolant, 0.4 wt% aqueous chitosan solution (molecular weight = 22 kDa), and a small amount of lactic acid as solvent at 0 °C. The resulting chitosan nanofibers may find application in biomedical and food engineering. Moreover, this new technology may be applicable to other natural and synthetic water-soluble polymers.
authors: Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2-4, Hibikino Wakamatsu-ku Kitakyushu-shi, Fukuoka 8080196, Japan; School of Food Science and Engineering, Yangzhou University, Yangzhou 225127, China. Electronic address: wang-yihan@edu.life.kyutech.ac.jp.
authors: Yihan
authors: Y
authors: Wang
authors: Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2-4, Hibikino Wakamatsu-ku Kitakyushu-shi, Fukuoka 8080196, Japan. Electronic address: wakisaka@life.kyutech.ac.jp.
authors: Minato
authors: M
authors: Wakisaka
mesh_terms: D048271:Chitosan / Q000737:chemistry*; D007053:Ice; D008970:Molecular Weight; D057139:Nanofibers / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D012997:Solvents / Q000737:chemistry; D013696:Temperature; D000069453:Ultrasonic Waves
chemical_list: D007053:Ice; D012997:Solvents; D048271:Chitosan
keywords: Acetic acid (PubChem CID: 176); Chitosan (PubChem CID: 71853); Chitosan nanofiber; Formic acid (PubChem CID: 284); Freeze casting; L-lactic acid (PubChem CID: 107689); Liquid nitrogen (PubChem CID: 947); Marine polysaccharides; Ultrasonic atomization