title: Daptomycin non-susceptible, vancomycin-intermediate Staphylococcus aureus endocarditis treated with ceftaroline and daptomycin: case report and brief review of the literature.
abstract: We report a case of clearance of persistent bacteremia due to daptomycin non-susceptible, vancomycin-intermediate Staphylococcus aureus native mitral valve endocarditis with a combination of ceftaroline and daptomycin, in an 81-year-old medically complex patient who was not an operative candidate.
authors: Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, 513 Parnassus Avenue, Med Science, Room S380, San Francisco, CA, 94143, USA. sanjiv.baxi@ucsf.edu.|Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA, USA. sanjiv.baxi@ucsf.edu.
authors: Sanjiv M
authors: SM
authors: Baxi
authors: Department of Clinical Pharmacy, University of California, San Francisco, San Francisco, CA, USA.
authors: Dominic
authors: D
authors: Chan
authors: Division of HIV/AIDS, San Francisco General Hospital, University of California, San Francisco, San Francisco, CA, USA.
authors: Vivek
authors: V
authors: Jain
mesh_terms: D000369:Aged, 80 and over; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology; D002511:Cephalosporins / Q000008:administration & dosage*; D017576:Daptomycin / Q000008:administration & dosage*; D024881:Drug Resistance, Bacterial; D004359:Drug Therapy, Combination; D004697:Endocarditis, Bacterial / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology*; D005260:Female; D006801:Humans; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification; D016896:Treatment Outcome; D000097583:Ceftaroline
chemical_list: D002511:Cephalosporins; D017576:Daptomycin; D000097583:Ceftaroline
keywords: Antimicrobial resistance; Bacteremia; Ceftaroline; Endocarditis; Staphylococcus aureus