title: Intravitreal dexamethasone implant for cystoid macular edema and inflammation after scleral buckling.
abstract: OBJECTIVE
  Cystoid macular edema may occur following scleral buckling and therefore deteriorate the visual outcome. Inflammation may be the major causative factor in the development of postoperative cystoid macular edema. This case demonstrates the effectiveness of a dexamethasone implant as a treatment after the onset of choroidal inflammation and cystoid macular edema 6 months following scleral buckling and having visual acuity restored.
  
  
  METHODS
  A 59-year-old phakic woman treated with scleral buckling for macula-off retinal detachment presented 2 months after surgery with cystoid macular edema with choroidal inflammation. Optical coherence tomography and fluorescein angiography were performed. From the time of the diagnosis, the patient's condition had been nonresponsive to medical therapy and only partially responsive to sub-Tenon triamcinolone acetonide. An intravitreal implant with a sustained release of 0.7 mg dexamethasone was implanted.
  
  
  RESULTS
  Following an intravitreal injection with a dexamethasone implant, the macular edema subsided completely and optical coherence tomography showed decreased foveal thickness from 510 μm to 220 μm. Choroidal fluorescein leakage disappeared. Best-corrected visual acuity improved from 0.70 to 0.20 logMAR, a condition maintained throughout the 6 months of follow-up.
  
  
  CONCLUSIONS
  Cystoid macular edema and choroidal inflammation are difficult to treat, but the improvement observed in this case of post scleral buckling macular edema and choroidal inflammation showed how a dexamethasone implant proved to be useful during the 6-month follow-up.
authors: Department of Ophthalmology, University of Catania, Catania - Italy.
authors: Vincenza
authors: V
authors: Bonfiglio
authors: Matteo R
authors: MR
authors: Fallico
authors: Andrea
authors: A
authors: Russo
authors: Vittorio
authors: V
authors: De Grande
authors: Antonio
authors: A
authors: Longo
authors: Maurizio G
authors: MG
authors: Uva
authors: Michele
authors: M
authors: Reibaldi
authors: Teresio
authors: T
authors: Avitabile
mesh_terms: D002833:Choroiditis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D003907:Dexamethasone / Q000008:administration & dosage*; D004343:Drug Implants; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D058449:Intravitreal Injections; D008269:Macular Edema / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D011183:Postoperative Complications; D012163:Retinal Detachment / Q000601:surgery; D012591:Scleral Buckling; D041623:Tomography, Optical Coherence; D014222:Triamcinolone Acetonide / Q000008:administration & dosage; D014792:Visual Acuity / Q000502:physiology
chemical_list: D004343:Drug Implants; D005938:Glucocorticoids; D003907:Dexamethasone; D014222:Triamcinolone Acetonide