title: High hydrostatic pressure processing reduces the glycemic index of fresh mango puree in healthy subjects.
abstract: Dietary guidelines recommend the daily consumption of fruits; however, healthy and type 2 diabetes mellitus (T2DM) subjects receive conflicting messages regarding ingestion of fruits, such as mango, because of its sugar content. We investigated the effects of high hydrostatic pressure (HHP) processing of fresh mango puree (MP) on the glycemic indexes (GIs) and postprandial glycemic responses of 38 healthy Mexican subjects in a randomized cross-over clinical trial. Physicochemical characterization of MP included sugar profiles by HPLC-ELSD, starch, fibers, moisture, viscosity, swelling capacity and solubility properties of alcohol insoluble residue (AIR). The mean GI for HHP-MP was significantly lower (32.7 ± 13.4) than that of unprocessed-MP (42.7 ± 19.5). A significantly higher proportion of subjects showed a low GI following the consumption of HHP-MP compared to unprocessed-MP and none of them showed a high GI for the HHP-MP, compared to a significantly higher proportion for the unprocessed-MP. The viscosity and AIR solubility values of HHP-MP samples were significantly higher, which influenced glucose peaking later (Tmax) at 45 minutes and induced 20% lower AUC values than unprocessed-MP, corresponding to greater retardation indexes. The study findings support data stating that low GI fruits are appropriate for glycemic control and that mango may be included as part of healthy subjects' diets and potentially T2DM subjects' diets. Furthermore, HHP processing of mango may offer additional benefits for glycemic control, as its performance regarding GI, AUC and Tmax was significantly better than that of the unprocessed-MP. To our knowledge, this is the first report on the impact of this commercial non-thermal pasteurization technology on glucose metabolism.
authors: Clinical Nutrition and Obesity Research Center, School of Medicine, Tec Salud, Tecnológico de Monterrey, Campus Monterrey, Av. Morones Prieto 3000 Pte, Col. Los Doctores, C.P. 64710, Monterrey, NL, Mexico. lelizond@itesm.mx.
authors: Leticia
authors: L
authors: Elizondo-Montemayor
authors: Carmen
authors: C
authors: Hernández-Brenes
authors: Perla A
authors: PA
authors: Ramos-Parra
authors: Diana
authors: D
authors: Moreno-Sánchez
authors: Bianca
authors: B
authors: Nieblas
authors: Aratza M
authors: AM
authors: Rosas-Pérez
authors: Ana C
authors: AC
authors: Lamadrid-Zertuche
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D055598:Chemical Phenomena; D018592:Cross-Over Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000032:analysis; D004043:Dietary Fiber / Q000008:administration & dosage / Q000032:analysis; D005215:Fasting; D005260:Female; D005511:Food Handling / Q000379:methods*; D005638:Fruit / Q000737:chemistry; D038321:Glycemic Index; D064368:Healthy Volunteers; D006801:Humans; D006874:Hydrostatic Pressure; D007328:Insulin / Q000097:blood; D008297:Male; D031022:Mangifera / Q000737:chemistry*; D008800:Mexico; D008875:Middle Aged; D019518:Postprandial Period; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D004043:Dietary Fiber; D007328:Insulin