title: Techniques for intraoperative radiation therapy for early-stage breast carcinoma.
abstract: Intraoperative radiation therapy (IORT) is a method of accelerated partial breast irradiation developed to replace other longer courses of radiotherapy with a single radiation session administered at the time of breast-conserving surgery. The purpose of this review is to summarize the advantages and disadvantages of breast IORT techniques that are currently available, as well to consider potential alternative techniques for breast IORT or ultra-short course breast radiotherapy. Furthermore, we highlight the published outcomes for the IORT treatment approaches including: electron therapy, superficial photon therapy and other techniques. Potential future directions of IORT are explored including novel IORT techniques utilizing intraoperative brachytherapy with in-room imaging and rapid treatment planning.
authors: Department of Radiation Oncology, University of Virginia School of Medicine, Charlottesville, VA, USA.
authors: Daniel M
authors: DM
authors: Trifiletti
authors: Ryan
authors: R
authors: Jones
authors: Shayna L
authors: SL
authors: Showalter
authors: Bruce B
authors: BB
authors: Libby
authors: David R
authors: DR
authors: Brenin
authors: Anneke
authors: A
authors: Schroen
authors: Monica M
authors: MM
authors: Morris
authors: Kelli A
authors: KA
authors: Reardon
authors: Timothy N
authors: TN
authors: Showalter
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007430:Intraoperative Care / Q000379:methods*; D009367:Neoplasm Staging
keywords: APBI; IORT; brachytherapy; breast; intraoperative; summary