title: The autoimmune concept of multiple sclerosis.
abstract: Multiple sclerosis (MS) is a chronic inflammatory and demyelinating disease of the central nervous system (CNS). With growing evidence for environmental and genetic factors, MS is now accepted as an autoimmune disease. This complex disease seems to implicate various cell types in both innate and adaptive compartments. Here, we discuss recent advances in the immunological field of MS research.
authors: CHU de Nantes, service de neurologie, Inserm CR1064, 44093 Nantes cedex, France.
authors: Bryan
authors: B
authors: Nicol
authors: CHU de Nantes, service de neurologie, Inserm CR1064, 44093 Nantes cedex, France.
authors: Marion
authors: M
authors: Salou
authors: CHU de Nantes, service de neurologie, Inserm CR1064, 44093 Nantes cedex, France. Electronic address: david.laplaud@univ-nantes.fr.
authors: David-Axel
authors: DA
authors: Laplaud
authors: Max Planck institute of neurobiology, department of neuroimmunology, Planegg-Martinsried, 31, 81377 Munich, Germany.
authors: Hartmut
authors: H
authors: Wekerle
mesh_terms: D056704:Adaptive Immunity; D000818:Animals; D015551:Autoimmunity; D004195:Disease Models, Animal; D006801:Humans; D009103:Multiple Sclerosis / Q000276:immunology* / Q000473:pathology / Q000628:therapy