title: The interface of depression and cardiovascular disease: therapeutic implications.
abstract: Patients with major depression are at an increased risk for developing cardiovascular disease, respond more poorly to treatment, and exhibit worse outcomes, including increased morbidity and mortality. This article reviews the relationship between depression and heart disease, with an emphasis on epidemiology, biological substrates that likely underlie this relationship, and implications for treatment.
authors: Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, Florida.
authors: Fred
authors: F
authors: Seligman
authors: Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, Florida.
authors: Charles B
authors: CB
authors: Nemeroff
mesh_terms: D000818:Animals; D001519:Behavior / Q000502:physiology; D002318:Cardiovascular Diseases / Q000209:etiology / Q000523:psychology* / Q000628:therapy*; D003327:Coronary Disease / Q000523:psychology / Q000628:therapy; D003863:Depression / Q000150:complications* / Q000503:physiopathology / Q000628:therapy*; D003866:Depressive Disorder / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D006339:Heart Rate / Q000502:physiology; D006801:Humans
keywords: antidepressants; cardiovascular disease; depression; mood disorders; platelets