title: Sleep Quality and Risk of Dementia Among Older Male Veterans.
abstract: OBJECTIVE
  To determine whether a diagnosis of sleep disturbance is associated with dementia in older veterans.
  
  
  METHODS
  For this retrospective cohort study, we obtained medical record data from the Department of Veterans Affairs National Patient Care Database for 200,000 randomly selected veterans aged 55 years and older. Prevalent cases of dementia from the baseline period (2000-2003) were excluded, leaving an analytic sample of 179,738 male veterans. Follow-up took place from 2004 to 2011. The primary outcome was all-cause dementia, ascertained using International Classification of Disease, Ninth Revision codes. Sleep disturbance, the primary predictor, was also ascertained using these codes.
  
  
  RESULTS
  After adjusting for potential confounders, those with sleep disturbance had a 27% increased risk of dementia (hazard ratio: 1.27; 95% confidence interval: 1.20-1.34).
  
  
  CONCLUSIONS
  Sleep disturbance was associated with increased risk of dementia among a large cohort of older, primarily male veterans.
authors: Department of Psychiatry, University of California San Francisco, San Francisco, CA; Department of Neurology, University of California San Francisco, San Francisco, CA; Department of Epidemiology, University of California San Francisco, San Francisco, CA; Department of Biostatistics, University of California San Francisco, San Francisco, CA; San Francisco Veteran Affairs Medical Center, San Francisco, CA. Electronic address: Kristine.yaffe@ucsf.edu.
authors: Kristine
authors: K
authors: Yaffe
authors: Department of Psychiatry, University of California San Francisco, San Francisco, CA.
authors: Jasmine
authors: J
authors: Nettiksimmons
authors: Departments of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Palo Alto, CA; Palo Alto Veteran Affairs Medical Center, Palo Alto, CA.
authors: Jerome
authors: J
authors: Yesavage
authors: Department of Psychiatry, University of California San Francisco, San Francisco, CA; San Francisco Veteran Affairs Medical Center, San Francisco, CA.
authors: Amy
authors: A
authors: Byers
mesh_terms: D000368:Aged; D003704:Dementia / Q000453:epidemiology* / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012893:Sleep Wake Disorders / Q000150:complications / Q000453:epidemiology*; D014481:United States / Q000453:epidemiology; D014728:Veterans / Q000706:statistics & numerical data*
keywords: Sleep; dementia; veterans