title: Preparation and preliminary dialysis performance research of polyvinylidene fluoride hollow fiber membranes.
abstract: In this study, the separation properties of Polyvinylidene fluoride (PVDF) hollow fiber hemodialysis membranes were improved by optimizing membrane morphology and structure. The results showed that the PVDF membrane had better mechanical and separation properties than Fresenius Polysulfone High-Flux (F60S) membrane. The PVDF membrane tensile stress at break, tensile elongation and bursting pressure were 11.3 MPa, 395% and 0.625 MPa, respectively. Ultrafiltration (UF) flux of pure water reached 108.2 L∙h-1∙m-2 and rejection of Albumin from bovine serum was 82.3%. The PVDF dialyzers were prepared by centrifugal casting. The influences of membrane area and simulate fluid flow rate on dialysis performance were investigated. The results showed that the clearance rate of urea and Lysozyme (LZM) were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA) had little influence. The high-flux PVDF dialyzer UF coefficient reached 62.6 mL/h/mmHg. The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea. The clearance rate of LZM was 66.8% and urea was 87.7%.
authors: Institute of Biological and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, China. haiyang19802005@163.com.
authors: Qinglei
authors: Q
authors: Zhang
authors: Institute of Biological and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, China. luxiaolong@263.net.|State Key Laboratory of Hollow Fiber Membrane Materials and Membrane Processes, Tianjin Polytechnic University, Tianjin 300387, China. luxiaolong@263.net.
authors: Xiaolong
authors: X
authors: Lu
authors: Tianjin Third Central Hospitals, Tianjin 300170, China. athena196121@163.com.
authors: Juanjuan
authors: J
authors: Liu
authors: Institute of Biological and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, China. 13516211811@139.com.
authors: Lihua
authors: L
authors: Zhao