title: Palladium-catalyzed three-component cascade reaction: facial access to densely functionalized indolizines.
abstract: A palladium-catalyzed three-component cascade reaction of 2-(2-enynyl)pyridines with nucleophiles and allyl halides has been developed, enabling the synthesis of densely functionalized indolizines in moderate to good yields. The newly developed methodology offers several practical advantages, including operational simplicity, ready availability of starting materials, and mild reaction conditions.
authors: College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014 (P. R. China).
authors: Ren-Rong
authors: RR
authors: Liu
authors: Chuan-Jun
authors: CJ
authors: Lu
authors: Ming-Di
authors: MD
authors: Zhang
authors: Jian-Rong
authors: JR
authors: Gao
authors: Yi-Xia
authors: YX
authors: Jia
keywords: cascade reactions; cyclization; enynes; heterocycles; palladium