title: Can metabolic disorders in aging men contribute to prostatic hyperplasia eligible for transurethral resection of the prostate (TURP)?
abstract: OBJECTIVE
  The aim of this study was to evaluate the incidence and severity of metabolic disorders occurring in the metabolic syndrome in patients with benign prostatic hyperplasia eligible for surgical treatment.
  
  
  METHODS
  The study group consisted men with diagnosed benign prostatic hyperplasia. The control group consisted patients recruited from basic health care units. Abdominal circumference, body weight and blood serum metabolic parameters were determined in the experimental and control groups. The concentrations of glucose were determined, as well as total cholesterol (ChT), low-density lipoprotein (LDL), high density lipoprotein (HDL) and triglycerides (TAG), by spectrophotometric method using reagent kits.
  
  
  RESULTS
  In the study group 91 (60.3%) cases of metabolic syndrome (MetS) were diagnosed, while in the control group 71 (46.1%) men met the diagnostic criteria for this syndrome (p=0.018). The analysis shows a relationship between MetS in patients with BPH and concentration glucose, ChT, LDL, HDL, systolic blood pressure and diastolic blood pressure. We found no significant statistical relationship between body weight, abdominal circumference and concentration TAG, hypertension in patients and controls.
  
  
  CONCLUSIONS
  in the study presented in this article, statistically significant relationships between BPH and the diagnostic parameters of the metabolic syndrome were demonstrated. These results indicate to the necessity of the modification of the lifestyle, taking preventive measures in diabetes, and evaluation of lipid metabolism disorders. It is recommended to assess symptoms that may suggest BPH (as a manifestation of LUTS) in men over 50 years of age with diagnoses of metabolic disorders (including MetS), and provide them with specialist urological care in order to prevent surgical treatment of the prostate.
authors: Department of Histology and Developmental Biology, Pomeranian Medical University, Szczecin 71-210, Poland. ryl.ola@poczta.gmail.com.
authors: Aleksandra
authors: A
authors: Rył
authors: Laboratory of Rehabilitation Medicine, Pomeranian Medical University, Szczecin 71-210, Poland. iwona.rotter@pum.edu.pl.
authors: Iwona
authors: I
authors: Rotter
authors: Department of Urology and Urological Oncology, Pomeranian Medical University, Szczecin 71-111, Poland. mslojewski@gmail.com.
authors: Marcin
authors: M
authors: Słojewski
authors: Laboratory Diagnostics and Molecular Medicine, Department of Laboratory Medicine, Pomeranian Medical University, Szczecin 71-111, Poland. adriana.jedrzychowska@gmail.com.
authors: Adriana
authors: A
authors: Jędrzychowska
authors: Laboratory Diagnostics and Molecular Medicine, Department of Laboratory Medicine, Pomeranian Medical University, Szczecin 71-111, Poland. zuzia26@o2.pl.
authors: Zuzanna
authors: Z
authors: Marcinowska
authors: Department of Histology and Developmental Biology, Pomeranian Medical University, Szczecin 71-210, Poland. grabowska.marta.anna@gmail.com.
authors: Marta
authors: M
authors: Grabowska
authors: Department of Histology and Developmental Biology, Pomeranian Medical University, Szczecin 71-210, Poland. maria@laszczynska.pl.
authors: Maria
authors: M
authors: Laszczyńska
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D006801:Humans; D015994:Incidence; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000209:etiology* / Q000601:surgery; D012720:Severity of Illness Index; D020728:Transurethral Resection of Prostate