title: Multiple lentigines confined to psoriatic plaques induced by biologic agents in psoriasis therapy: a case and review of the literature.
abstract: Multiple lentigines confined to psoriatic plaques is a rare entity, which is more frequently recognized after the use of systemic biologic agents for psoriasis therapy. Although this phenomenon was previously accepted as a postinflammatory reaction, recent observations suggest psoriasis-related cytokines and their efficient supression by biologic agents strongly associate with melanogenesis and melanocytic proliferation. Hereby, we report a patient who developed multiple lentigines arising in resolved psoriatic plaques induced by infliximab and review similar cases reported in the literature induced after biologic treatments of psoriasis.
authors: Department of Dermatology and Venerology, Hacettepe University Faculty of Medicine , Ankara , Turkey.
authors: Sibel
authors: S
authors: Dogan
authors: Nilgün
authors: N
authors: Atakan
mesh_terms: D005260:Female; D006801:Humans; D007911:Lentigo / Q000150:complications*; D008875:Middle Aged; D011565:Psoriasis / Q000150:complications*
keywords: Biologic agent; lentigine; psoriasis; treatment