title: [Unilateral isolated Raynaud's phenomenon leading to diagnosis of multifocal giant-cell arteritis complicated with renal ischemia].
abstract: We report a case of a 76-year-old woman with isolated unilateral Raynaud phenomenon revealing giant-cell arteritis with diffuse arterial lesions and bilateral renal artery stenosis. Doppler ultrasonography showed bilateral stenosis of the subclavian and axillary arteries. Angio-CT PET enlightened diffuse arterial lesions, mainly involving the aorta and the brachial and femoral arteries as well as bilateral renal ostial stenosis with right kidney ischemia. Diagnosis of giant-cell arteritis was made on the temporal artery biopsy. Corticosteroid therapy led to rapid clinical and radiological improvement. Clinical manifestations of giant-cell arteritis may be atypical. Diffuse arterial disease may exist in the absence of cephalic symptoms or significant inflammatory biological features. Ostial renal artery stenosis may induce potentially threatening renal ischemia.
authors: Service de médecine interne, CHU de Tours, université François-Rabelais, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
authors: J
authors: J
authors: Goupil de Bouillé
authors: Service de médecine interne, CHU de Tours, université François-Rabelais, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
authors: M
authors: M
authors: Lecouffe-Desprets
authors: Service de médecine interne, CHU de Tours, université François-Rabelais, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
authors: A
authors: A
authors: Bigot
authors: EA-4245, service de néphrologie-immunologie clinique, CHU de Tours, université François-Rabelais, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
authors: J-M
authors: JM
authors: Halimi
authors: Service de médecine nucléaire, CHU de Tours, université François-Rabelais, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
authors: M
authors: M
authors: Courtehoux
authors: Service de médecine interne, CHU de Tours, université François-Rabelais, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
authors: J-L
authors: JL
authors: Guilmot
authors: Cabinet d'angiologie, 17, place de la Tranchée, 37100 Tours, France.
authors: C
authors: C
authors: Breteau
authors: Service de médecine interne, CHU de Tours, université François-Rabelais, 2, boulevard Tonnellé, 37044 Tours cedex 9, France. Electronic address: ediot@med.univ-tours.fr.
authors: E
authors: E
authors: Diot
mesh_terms: D000368:Aged; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D007511:Ischemia / Q000150:complications*; D007668:Kidney / Q000098:blood supply*; D011928:Raynaud Disease / Q000209:etiology*
keywords: Aortite; Aortitis; Artérite à cellules géantes; Giant-cell arteritis; Phénomène de Raynaud; Raynaud phenomenon; Renal artery stenosis; Sténose des artères rénales