title: Canaloplasty versus non-penetrating deep sclerectomy - a prospective, randomised study of the safety and efficacy of combined cataract and glaucoma surgery; 12-month follow-up.
abstract: OBJECTIVE
  To compare outcomes of phaco-canaloplasty (PC) and phaco-non-penetrating deep sclerectomy (PDS) with a viscoelastic compound.
  
  
  METHODS
  This study included 29 eyes after PC and 30 after PDS. Indications were uncontrolled primary open-angle glaucoma (POAG) and a cataract. Corrected distance visual acuity (CDVA), intraocular pressure (IOP), and number of medications were evaluated. Follow-up examinations were performed on days 1 and 7, and after 1, 3, 6, and 12 months. Complete and qualified success was an IOP ≤ 18 mmHg.
  
  
  RESULTS
  At the 12-month follow-up, mean IOP decreased in the PC group from 19.0 ±6.9 mmHg to 12.6 ±2.7 mmHg, and in the PDS group, from 19.1 ±5.8 mmHg to 14.3 ±3.5 mmHg (P < 0.05). Both groups preoperatively and at 12 months showed no significant differences in IOP (P > 0.05). There was no statistically significant difference between the number of medications used (P > 0.05). Complete and qualified success rates for both groups were 79.0 % and 76.9 % (P = 0.701). The most frequent postoperative PC complication was hyphema (58.0 %); for PDS, bleb fibrosis was most frequent (26.7 %). No PC patients required postoperative management. PDS patients required postoperative interventions 58.7 % of the time, including a 5-fluorouracil (5-FU) injection (58.7 %), suture lysis (48.3 %), and needling (27.6 %).
  
  
  CONCLUSIONS
  Both PC and PDS lead to an effective decrease in IOP on a short-term follow-up basis and demonstrate similar efficacy and safety profiles. PDS patients required additional procedures including 5-FU injections, suture lysis, or needling. PC patients required no additional procedures.
authors: Department of Ophthalmology, Military Institute of Medicine, Szaserów 128 STR., 04-141, Warsaw, Poland, rekaspl@gmail.com.
authors: Marek
authors: M
authors: Rękas
authors: Anna
authors: A
authors: Byszewska
authors: Katarzyna
authors: K
authors: Petz
authors: Joanna
authors: J
authors: Wierzbowska
authors: Anselm
authors: A
authors: Jünemann
mesh_terms: D000368:Aged; D002386:Cataract / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D003886:Descemet Membrane / Q000601:surgery; D005260:Female; D018463:Filtering Surgery / Q000009:adverse effects / Q000379:methods*; D005902:Glaucoma, Open-Angle / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007431:Intraoperative Complications; D008297:Male; D018918:Phacoemulsification / Q000009:adverse effects / Q000379:methods*; D011183:Postoperative Complications; D011446:Prospective Studies; D012599:Sclerostomy; D013536:Suture Techniques; D014065:Tonometry, Ocular; D014129:Trabecular Meshwork / Q000601:surgery; D016896:Treatment Outcome; D055675:Viscosupplements / Q000008:administration & dosage; D014792:Visual Acuity / Q000502:physiology
chemical_list: D055675:Viscosupplements