title: Relationships (II) of International Classification of High-resolution Computed Tomography for Occupational and Environmental Respiratory Diseases with ventilatory functions indices for parenchymal abnormalities.
abstract: The International Classification of High-Resolution Computed Tomography (HRCT) for Occupational and Environmental Respiratory Diseases (ICOERD) is used to screen and diagnose respiratory illnesses. Using univariate and multivariate analysis, we investigated the relationship between subject characteristics and parenchymal abnormalities according to ICOERD, and the results of ventilatory function tests (VFT). Thirty-five patients with and 27 controls without mineral-dust exposure underwent VFT and HRCT. We recorded all subjects' occupational history for mineral dust exposure and smoking history. Experts independently assessed HRCT using the ICOERD parenchymal abnormalities (Items) grades for well-defined rounded opacities (RO), linear and/or irregular opacities (IR), and emphysema (EM). High-resolution computed tomography showed that 11 patients had RO; 15 patients, IR; and 19 patients, EM. According to the multiple regression model, age and height had significant associations with many indices ventilatory functions such as vital capacity, forced vital capacity, and forced expiratory volume in 1 s (FEV1). The EM summed grades on the upper, middle, and lower zones of the right and left lungs also had significant associations with FEV1 and the maximum mid-expiratory flow rate. The results suggest the ICOERD notation is adequate based on the good and significant multiple regression modeling of ventilatory function with the EM summed grades.
authors: Department of Environmental Health, University of Fukui School of Medicine, Japan.
authors: Taro
authors: T
authors: Tamura
authors: Narufumi
authors: N
authors: Suganuma
authors: Kurt G
authors: KG
authors: Hering
authors: Tapio
authors: T
authors: Vehmas
authors: Harumi
authors: H
authors: Itoh
authors: Masanori
authors: M
authors: Akira
authors: Yoshihiro
authors: Y
authors: Takashima
authors: Harukazu
authors: H
authors: Hirano
authors: Yukinori
authors: Y
authors: Kusaka
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D004391:Dust; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D008875:Middle Aged; D008903:Minerals / Q000009:adverse effects; D016273:Occupational Exposure / Q000009:adverse effects*; D011009:Pneumoconiosis / Q000145:classification / Q000000981:diagnostic imaging / Q000503:physiopathology; D011859:Radiography; D012129:Respiratory Function Tests; D012140:Respiratory Tract Diseases / Q000145:classification* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed
chemical_list: D004391:Dust; D008903:Minerals