title: Bone marrow metastasis of rhabdomyosarcoma mimicking acute leukemia: a case report and review of the literature.
abstract: Bone marrow metastasis of rhabdomyosarcoma has been reported to be difficult to distinguish from acute leukemia. We herein describe a case of rhabdomyosarcoma with bone marrow metastasis mimicking acute lymphoblastic leukemia. A 29-year-old woman was admitted with thrombocytopenia, blast-like cells in the peripheral blood and a coagulation disorder. Bone marrow aspirates showed 94.8% blast-like cell infiltration (CD45(-), myeloperoxidase(-), and CD56(+)), and CT scan revealed the presence of an infiltrating mass in the nasal cavity. Based on a biopsy of the nasal cavity, the patient was diagnosed with rhabdomyosarcoma exhibiting bone marrow metastasis. She received chemotherapy, followed by radiation therapy, and has since remained alive for 26 months, as of the last follow-up.
authors: Department of Hematology, Nagano Red Cross Hospital, Japan.
authors: Yuka
authors: Y
authors: Aida
authors: Toshimitsu
authors: T
authors: Ueki
authors: Takehiko
authors: T
authors: Kirihara
authors: Wataru
authors: W
authors: Takeda
authors: Taro
authors: T
authors: Kurihara
authors: Keijiro
authors: K
authors: Sato
authors: Ikuo
authors: I
authors: Shimizu
authors: Yuki
authors: Y
authors: Hiroshima
authors: Masahiko
authors: M
authors: Sumi
authors: Mayumi
authors: M
authors: Ueno
authors: Naoaki
authors: N
authors: Ichikawa
authors: Masahide
authors: M
authors: Watanabe
authors: Hikaru
authors: H
authors: Kobayashi
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001853:Bone Marrow / Q000473:pathology*; D019046:Bone Marrow Neoplasms / Q000150:complications / Q000556:secondary*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007938:Leukemia / Q000175:diagnosis*; D012208:Rhabdomyosarcoma / Q000150:complications / Q000556:secondary*; D013921:Thrombocytopenia / Q000209:etiology*; D016896:Treatment Outcome