title: Bacterial genome remodeling through bacteriophage recombination.
abstract: Bacteriophages co-exist and co-evolve with their hosts in natural environments. Virulent phages lyse infected cells through lytic cycles, whereas temperate phages often remain dormant and can undergo lysogenic or lytic cycles. In their lysogenic state, prophages are actually part of the host genome and replicate passively in rhythm with host division. However, prophages are far from being passive residents: they can modify or bring new properties to their host. In this review, we focus on two important phage-encoded recombination mechanisms, i.e. site-specific recombination and homologous recombination, and how they remodel bacterial genomes.
authors: Laboratoire de Chimie Bactérienne, UMR7283, Centre National de la Recherche Scientifique, Aix Marseille Université, 13402 Marseille Cedex 20, France.
authors: Rachid
authors: R
authors: Menouni
authors: Institut National de la Recherche Agronomique, Micalis, UMR 1319, F-78350 Jouy en Josas, France.
authors: Geoffrey
authors: G
authors: Hutinet
authors: Institut National de la Recherche Agronomique, Micalis, UMR 1319, F-78350 Jouy en Josas, France.
authors: Marie-Agnès
authors: MA
authors: Petit
authors: Laboratoire de Chimie Bactérienne, UMR7283, Centre National de la Recherche Scientifique, Aix Marseille Université, 13402 Marseille Cedex 20, France mireille.ansaldi@imm.cnrs.fr.
authors: Mireille
authors: M
authors: Ansaldi
mesh_terms: D001435:Bacteriophages / Q000235:genetics*; D015321:Gene Rearrangement; D016680:Genome, Bacterial; D006790:Host-Parasite Interactions; D039002:Prophages / Q000235:genetics; D011995:Recombination, Genetic
keywords: bacteriophage; homologous; lysogeny; recombination; site-specific recombination