title: Alkyl Aryl Ether Bond Formation with PhenoFluor.
abstract: An alkyl aryl ether bond formation reaction between phenols and primary and secondary alcohols with PhenoFluor has been developed. The reaction features a broad substrate scope and tolerates many functional groups, and substrates that are challenging for more conventional ether bond forming processes may be coupled. A preliminary mechanistic study indicates reactivity distinct from conventional ether bond formation.
authors: Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford St., Cambridge, MA 02138 (USA) http://www.rittergroup.org.
authors: Xiao
authors: X
authors: Shen
authors: Constanze N
authors: CN
authors: Neumann
authors: Claudia
authors: C
authors: Kleinlein
authors: Nathaniel W
authors: NW
authors: Goldberg
authors: Tobias
authors: T
authors: Ritter
mesh_terms: D000438:Alcohols / Q000737:chemistry; D004987:Ethers / Q000138:chemical synthesis* / Q000737:chemistry; D048288:Imidazolines / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000438:Alcohols; D004987:Ethers; D048288:Imidazolines; C583239:PhenoFluor
keywords: CO bond formation; Mitsunobu reaction; PhenoFluor; alkyl aryl ethers; fluorine