title: Thermodynamically Controlled, Dynamic Binding of Diols to a 1,2-BN Cyclohexane Derivative.
abstract: The reversible covalent binding of diols to anN-Bn 1,2-BN cyclohexane has been studied by11B and1H NMR spectroscopy and single-crystal X-ray diffraction analysis. The activation barrier for the reversible B-N Lewis acid-base interaction has been measured by variable-temperature NMR with bound (2R,3R)-(-)-2,3-butanediol (Tc= -40 °C, ΔG‡= 11.2 ± 0.2 kcal mol-1). Deuterium labeling experiments demonstrate that ligand exchange is reversible and rapid at room temperature, and competitive binding studies establish diol association as a thermodynamically controlled process.
authors: Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403-1253, United States.
authors: Gregory P
authors: GP
authors: Harlow
authors: Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403-1253, United States.
authors: Lev N
authors: LN
authors: Zakharov
authors: Department of Chemistry, Queen's University, Kingston, Ontario K7L 3N6, Canada.
authors: Gang
authors: G
authors: Wu
authors: Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403-1253, United States.
authors: Shih-Yuan
authors: SY
authors: Liu