title: Diagnostic yield of endoscopic ultrasound in patients with hypoglicemia and insulinoma suspected.
abstract: OBJECTIVE
  Noninvasive imaging techniques have shown limitations to identify insulinomas. In few studies reported so far, endoscopic ultrasound (EUS) has proven to be able to locate lesions. The aim of this study was to compare the performance of computed tomography versus EUS for the detection of insulinomas.
  
  
  METHODS
  In a retrospective manner prospectively collected data were analyzed. Patients with hypoglucemia and hyperinsulinemia were included. Diagnostic yield was measured in relationship to sensitivity, specificity, positive predictive value, negative predictive value and accuracy. Surgical specimens were considered the gold standard.
  
  
  RESULTS
  Sensitivity, positive predictive value, and accuracy of EUS was 100%, 95.4% and 95.4%, respectively. In the case of CT the sensitivity was 60%, specificity 100%, positive predictive value 100%, negative predictive value 7%, and accuracy were 68%.
  
  
  CONCLUSIONS
  EUS is useful in the preoperative assessment of patients with hypoglycemia and serum hyperinsulinemia.
authors: Department of Gastrointestinal Endoscopy, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City, México.
authors: Félix Ignacio
authors: FI
authors: Téllez-Ávila
authors: Department of Gastrointestinal Endoscopy, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City, México.
authors: Gladys Yolanda
authors: GY
authors: Acosta-Villavicencio
authors: Department of Surgery, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City, México.
authors: Carlos
authors: C
authors: Chan
authors: Department of Gastroenterology, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City, México.
authors: Jorge
authors: J
authors: Hernández-Calleros
authors: Department of Gastroenterology, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City, México.
authors: Luis
authors: L
authors: Uscanga
authors: Department of Gastrointestinal Endoscopy, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City, México.
authors: Francisco
authors: F
authors: Valdovinos-Andraca
authors: Department of Gastrointestinal Endoscopy, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City, México.
authors: Miguel Ángel
authors: MÁ
authors: Ramírez-Luna
keywords: Endoscopic ultrasound; insulinoma; pancreatic neuroendocrine tumors