title: A novel approach for studying histone H1 function in vivo.
abstract: In this report, we investigate the mechanisms that regulate Drosophila histone H1 expression and its association with chromatin in vivo. We show that histone H1 is subject to negative autoregulation and exploit this result to examine the effects of mutations of the main phosphorylation site of histone H1.
authors: Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064.
authors: Giorgia
authors: G
authors: Siriaco
authors: Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064.
authors: Renate
authors: R
authors: Deuring
authors: Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064.
authors: Gina D
authors: GD
authors: Mawla
authors: Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064 tamkun@ucsc.edu.
authors: John W
authors: JW
authors: Tamkun
mesh_terms: D000818:Animals; D002843:Chromatin / Q000235:genetics; D004330:Drosophila / Q000235:genetics* / Q000378:metabolism; D029721:Drosophila Proteins / Q000235:genetics* / Q000378:metabolism; D049452:Green Fluorescent Proteins / Q000235:genetics / Q000378:metabolism; D006657:Histones / Q000235:genetics* / Q000378:metabolism; D008856:Microscopy, Fluorescence / Q000379:methods
chemical_list: D002843:Chromatin; D029721:Drosophila Proteins; D006657:Histones; D049452:Green Fluorescent Proteins
keywords: Drosophila; chromatin; gene expression; histone H1