title: External cervical resorption associated with the use of bisphosphonates: a case series.
abstract: Although the pathogenesis and etiology of external cervical resorption (ECR) are not well understood, several predisposing factors have been reported to potentially contribute toward the initiation of ECR. However, a potential link between systemic medication and ECR has not been reported. Bisphosphonates (BSPs) are 1 group of these medications (the amino-containing BSP), which are associated with an acute-phase response and the release of proinflammatory cytokines, which could be associated with the initiation of ECR. Therefore, a possible causal link between BSPs and ECR could be drawn.
authors: Endodontic Postgraduate Unit, King's College London Dental Institute; Specialist Practice, London, United Kingdom. Electronic address: shanonpatel@gmail.com.
authors: Shanon
authors: S
authors: Patel
authors: Endodontic Postgraduate Unit, King's College London Dental Institute.
authors: Navid
authors: N
authors: Saberi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D050071:Bone Density Conservation Agents / Q000009:adverse effects*; D004164:Diphosphonates / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D014057:Tomography, X-Ray Computed; D019237:Tooth Cervix / Q000000981:diagnostic imaging / Q000187:drug effects*; D014091:Tooth Resorption / Q000139:chemically induced* / Q000628:therapy
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates
keywords: Bisphosphonates; cone-beam computed tomographic imaging; etiology; external cervical resorption; osteoclasts; osteonecrosis of the jaw; proinflammatory cytokines