title: Indications for allo- and auto-SCT for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2015.
abstract: This is the sixth special report that the European Society for Blood and Marrow Transplantation regularly publishes on the current practice and indications for haematopoietic SCT for haematological diseases, solid tumours and immune disorders in Europe. Major changes have occurred in the field of haematopoietic SCT over the last years. Cord blood units as well as haploidentical donors have been increasingly used as stem cell sources for allo-SCT, thus, augmenting the possibility of finding a suitable donor for a patient. Continuous refinement of conditioning strategies has also expanded not only the number of potential indications but also has permitted consideration of older patients or those with co-morbidity for a transplant. There is accumulating evidence of the role of haematopoietic SCT in non-haematological disorders such as autoimmune diseases. On the other hand, the advent of new drugs and very effective targeted therapy has challenged the role of SCT in some instances or at least, modified its position in the treatment armamentarium of a given patient. An updated report with revised tables and operating definitions is presented.
authors: Department of Haematology, Institut Catala d'Oncologia, Hospital Duran I Reynals, Barcelona, Spain.
authors: A
authors: A
authors: Sureda
authors: Universitätsklinikum Frankfurt, Goethe-Universität, Klinik für Kinder- und Jugendmedizin, Frankfurt, Germany.
authors: P
authors: P
authors: Bader
authors: Paediatric Haematology Oncology, Policlinico G.B. Rossi, Verona, Italy.
authors: S
authors: S
authors: Cesaro
authors: Department of Internal Medicine V, University of Heidelberg, Heidelberg, Germany.
authors: P
authors: P
authors: Dreger
authors: Department of Haematology, Institut Catala d'Oncologia, Hospital Duran I Reynals, Barcelona, Spain.
authors: R F
authors: RF
authors: Duarte
authors: Clinical And Experimental Hematology Unit. Institute G. Gaslini, Genoa, Italy.
authors: C
authors: C
authors: Dufour
authors: Department of Haematology, Leiden University Medical Center, Leiden, The Netherlands.
authors: J H F
authors: JH
authors: Falkenburg
authors: Department of Haematology-BMT, Hopital St Louis, Paris, France.
authors: D
authors: D
authors: Farge-Bancel
authors: Children's BMT Unit, Great North Children's Hospital, Newcastle-Upon-Tyne, UK.
authors: A
authors: A
authors: Gennery
authors: Department of Stem Cell Transplantation, University hospital Eppendorf, Hamburg, Germany.
authors: N
authors: N
authors: Kröger
authors: Haematology and BMT Unit, Cremona, Italy.
authors: F
authors: F
authors: Lanza
authors: Department of Haematological Medicine, King's College Hospital/King's College London, London, UK.
authors: J C
authors: JC
authors: Marsh
authors: Chaim Sheva Medical Center, Tel-Hashomer, Israel.
authors: A
authors: A
authors: Nagler
authors: Stem Cell Transplantation Unit, St Anna Kinderspital, Vienna, Austria.
authors: C
authors: 0000000303698515
authors: C
authors: Peters
authors: Sezione di Ematologia, Dipartimento di Medicina Clinica e Sperimentale, Università di Perugia, Perugia, Italy.
authors: A
authors: A
authors: Velardi
authors: Department of Haematology, H. Saint Antoine, Paris, France.
authors: M
authors: M
authors: Mohty
authors: Anthony Nolan Research Institute, Royal Free and University College, London, UK.
authors: A
authors: A
authors: Madrigal
mesh_terms: D064591:Allografts; D064592:Autografts; D001327:Autoimmune Diseases / Q000628:therapy*; D046148:Donor Selection / Q000379:methods*; D005060:Europe; D005260:Female; D019337:Hematologic Neoplasms / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods* / Q000592:standards; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000628:therapy*; D014019:Tissue Donors