title: Lipases: Valuable catalysts for dynamic kinetic resolutions.
abstract: Dynamic kinetic resolutions have proven to be a useful method for the preparation of enantiopure compounds from racemates, leading to the formation of a single enantiomer in theoretically 100% yield. Because lipases are ubiquitous, versatile, stereoselective and robust biocatalysts, they have been successfully applied as co-catalysts in these reactions, being mostly combined with metals in the chemoenzymatic dynamic kinetic resolutions of alcohols and amines.
authors: Laboratory of Biocatalysis and Organic Synthesis, Universidade Federal do Rio de Janeiro, Instituto de Química, Cidade Universitária, Rio de Janeiro CEP21941909, Brazil. Electronic address: a.s.miranda@hotmail.com.
authors: Amanda S
authors: AS
authors: de Miranda
authors: Laboratory of Biocatalysis and Organic Synthesis, Universidade Federal do Rio de Janeiro, Instituto de Química, Cidade Universitária, Rio de Janeiro CEP21941909, Brazil.
authors: Leandro S M
authors: LS
authors: Miranda
authors: Laboratory of Biocatalysis and Organic Synthesis, Universidade Federal do Rio de Janeiro, Instituto de Química, Cidade Universitária, Rio de Janeiro CEP21941909, Brazil.
authors: Rodrigo O M A
authors: RO
authors: de Souza
mesh_terms: D055162:Biocatalysis; D001709:Biotechnology; D007700:Kinetics; D008049:Lipase; D013237:Stereoisomerism
chemical_list: D008049:Lipase
keywords: Chemoenzymatic synthesis; Dynamic kinetic resolution; Enantioselectivity; Enzyme catalysis; Lipases; Racemization