title: Endoscopic findings and lesion distribution in amebic colitis.
abstract: A retrospective cohort study was conducted in 55 symptomatic patients with amebic colitis that visited at St. Luke's International Hospital and Mie University Hospital from 1994 through 2013. To diagnose amebic colitis, 40 patients underwent total colonoscopy within 1 week after hospital visiting and before receiving any treatment. The percentage of characteristic endoscopic findings of amebic colitis including discrete ulcers or erosions with white or yellow exudates were 0% in terminal ileum, 93% in cecum, 28% in ascending, 25% in transverse, 15% in descending, 20% in sigmoid colon and 45% in rectum. The rectal lesions in 55% of patients with amebic colitis were nonspecific. The trophozoite identification rate by direct smear of intestinal tract washings performed during colonoscopy was 88%. The protozoan identification rate was 70% in biopsy specimens taken from the periphery of the characteristic discrete ulcers. Total colonoscopy should be considered for the diagnosis of amebic colitis.
authors: Department of Endoscopy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. Electronic address: nohoriki@clin.medic.mie-u.ac.jp.
authors: Noriyuki
authors: N
authors: Horiki
authors: Department of Infection, St. Luke's International Hospital, Tokyo, Japan.
authors: Keiichi
authors: K
authors: Furukawa
authors: Department of Endoscopy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
authors: Takashi
authors: T
authors: Kitade
authors: Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Japan.
authors: Takashi
authors: T
authors: Sakuno
authors: Department of Endoscopy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
authors: Masaki
authors: M
authors: Katsurahara
authors: Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Japan.
authors: Tetsuro
authors: T
authors: Harada
authors: Department of Endoscopy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
authors: Shunsuke
authors: S
authors: Tano
authors: Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Japan.
authors: Reiko
authors: R
authors: Yamada
authors: Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Japan.
authors: Yasuhiko
authors: Y
authors: Hamada
authors: Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Japan.
authors: Hiroyuki
authors: H
authors: Inoue
authors: Department of Endoscopy, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
authors: Kyosuke
authors: K
authors: Tanaka
authors: Department of Immunology, Mie University, Graduate School of Medicine, Tsu, Japan.
authors: Esteban C
authors: EC
authors: Gabazza
authors: Department of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
authors: Naoki
authors: N
authors: Ishii
authors: Department of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
authors: Katsuyuki
authors: K
authors: Fukuda
authors: Department of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
authors: Fumio
authors: F
authors: Omata
authors: Department of Gastroenterology, St. Luke's International Hospital, Tokyo, Japan.
authors: Yoshiyuki
authors: Y
authors: Fujita
authors: Department of Infectious Disease, Tokai University School of Medicine, Isehara, Japan.
authors: Hiroshi
authors: H
authors: Tachibana
authors: Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, Tsu, Japan.
authors: Yoshiyuki
authors: Y
authors: Takei
mesh_terms: D003113:Colonoscopy / Q000379:methods; D004404:Dysentery, Amebic / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
keywords: Amebiasis; Amebic colitis; Colonoscopy; Discrete ulcers; Endoscopy; Protozoa