title: Comorbid personality disorders in chronic fatigue syndrome patients: a marker of psychopathological severity.
abstract: BACKGROUND
  This study was designed to evaluate the presence of personality disorders (PDs) in Chronic Fatigue Syndrome (CFS) patients and to determine their influence on the severity of the associated psychopathology.
  
  
  METHODS
  132 CFS patients were assessed using SCID-I, Personality Diagnostic Questionnaire-4+ (PDQ-4+) with its Clinical Significance Scale, and Fatigue Impact Scale. The Beck Depression Inventory, Buss-Durkee Hostility Inventory and the State-Trait Anxiety Inventory were also administered.
  
  
  RESULTS
  48.5% patients presented PDs, being the most frequent the Obsessive-Compulsive and Avoidant ones. Patients with PDs had more depressive symptoms. Irritability, resentment, suspicion and guilt were the symptoms related with PDQ-4+ total score.
  
  
  CONCLUSIONS
  According to these results, PDs may be frequent in CFS patients. This comorbidity is associated with a complex clinical profile, secondary to more severe psychiatric symptoms.
authors: Departamento de Psiquiatría. Hospital Universitari Vall d&#8217;Hebron. CIBERSAM. Universitat Autònoma de Barcelona Departamento de Psiquiatría y Medicina Legal. Universitat Autònoma de Barcelona.
authors: Natalia
authors: N
authors: Calvo
authors: Departamento de Psiquiatría. Hospital Universitari Vall d&#8217;Hebron. CIBERSAM. Universitat Autònoma de Barcelona Departamento de Psiquiatría y Medicina Legal. Universitat Autònoma de Barcelona.
authors: Naia
authors: N
authors: Sáez-Francàs
authors: Departamento de Psiquiatría. Hospital Universitari Vall d&#8217;Hebron. CIBERSAM. Universitat Autònoma de Barcelona.
authors: Sergi
authors: S
authors: Valero
authors: Departamento de Medicina Interna. Hospital Universitari Vall d&#8217;Hebron. Departamento de Medicina Interna. Universitat Autònoma de Barcelona.
authors: José
authors: J
authors: Alegre
authors: Departamento de Psiquiatría. Hospital Universitari Vall d&#8217;Hebron. CIBERSAM. Universitat Autònoma de Barcelona Departamento de Psiquiatría y Medicina Legal. Universitat Autònoma de Barcelona.
authors: Miguel
authors: M
authors: Casas
mesh_terms: D003430:Cross-Sectional Studies; D015673:Fatigue Syndrome, Chronic / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010554:Personality Disorders / Q000150:complications*; D010556:Personality Tests; D011599:Psychopathology; D012720:Severity of Illness Index