title: Updating advances on recombinant human endostatin combined with radiotherapy for non-small cell lung cancer with brain metastasis.
abstract: Brain metastases (BM) heavily affects the prognosis of advanced non-small cell lung cancer (NSCLC). Although whole-brain radiotherapy remains the mainstream therapy for BM caused by NSCLC, the effectiveness is unsatisfactory. Endostar, a recombinant human endostatin (RHES), has shown certain therapeutic effect on advanced NSCLC. This article reviews the feasibility of Endostar combined with radiotherapy in the treatment of BM caused by NSCLC.
authors: Department of Radiation Oncology, Lianyungang First People's Hospital, Affiliated to Xuzhou Medical College, Lianyungang, China.
authors: Xiao-Dong
authors: XD
authors: Jiang
authors: Department of Radiation Oncology, Lianyungang First People's Hospital, Affiliated to Xuzhou Medical College, Lianyungang, China.
authors: Yun
authors: Y
authors: Qiao
keywords: Brain metastases; Non-small cell lung cancer; Radiotherapy; Recombinant human endostatin (Endostar)