title: Mesityl phenanthroline-modified 2'-deoxyuridine for heteroleptic complexes in metal ion-mediated assembly of DNA.
abstract: The synthesis of a new DNA building block that bears the metal ion ligand 2,9-bis-mesityl-3-ethynyl-phenanthroline attached to the 5-position of 2'-deoxyuridine is presented. In the presence of Zn(2+), Cu(2+), Fe(2+) and Ni(2+) the complex formation of an accordingly modified DNA double strand with a second DNA duplex bearing the 2,2':6',2''-terpyridine ligand was studied by optical spectroscopy. The selective formation of heteroleptic assemblies between the two different DNA pieces was evidenced by denaturing polyacrylamide gel electrophoresis.
authors: Institute of Organic Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany. Wagenknecht@kit.edu.
authors: Philipp
authors: P
authors: Ensslen
authors: Hans-Achim
authors: HA
authors: Wagenknecht
mesh_terms: D004247:DNA / Q000737:chemistry*; D003857:Deoxyuridine / Q000737:chemistry*; D019216:Metals, Heavy / Q000737:chemistry*; D010618:Phenanthrolines / Q000737:chemistry*
chemical_list: D019216:Metals, Heavy; D010618:Phenanthrolines; D004247:DNA; D003857:Deoxyuridine