title: Achievement of 1 H-19 F heteronuclear experiments using the conventional spectrometer with a shared single high band amplifier.
abstract: The (1)H-(19) F heteronuclear NMR experiments were achieved using the conventional spectrometer equipped with a single high band amplifier and a (1)H/(19)F/(13) C double-tuned probe. Although double high band amplifiers are generally required to perform such experiments, a simple modification of pathway in the conventional spectrometer was capable of acquiring various (1)H-(19)F heteronuclear spectra. The efficiency of the present technique was demonstrated in an application for (19)F{(1)H} and (1)H{(19)F} saturation transfer difference experiments.
authors: School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Horinouchi, Hachioji, Tokyo, 192-0392, Japan.
authors: Chiseko
authors: C
authors: Sakuma
authors: Jun-ichi
authors: J
authors: Kurita
authors: Kazuo
authors: K
authors: Furihata
authors: Mitsuru
authors: M
authors: Tashiro
mesh_terms: D000465:Algorithms; D000669:Amplifiers, Electronic; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005461:Fluorine / Q000032:analysis* / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000295:instrumentation* / Q000379:methods; D066244:Proton Magnetic Resonance Spectroscopy / Q000295:instrumentation*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*
chemical_list: D005461:Fluorine
keywords: 19F NMR; 19F{1H} and 1H{19F} STD; 1H-19F heteronuclear experiments; conventional spectrometer