title: Non-aqueous sol-gel synthesis of ultra small persistent luminescence nanoparticles for near-infrared in vivo imaging.
abstract: Ultra-small ZnGa2 O4 :Cr(3+) nanoparticles (6 nm) that exhibit near-infrared (NIR) persistent luminescence properties are synthesized by using a non-aqueous sol-gel method assisted by microwave irradiation. The nanoparticles are pegylated, leading to highly stable dispersions under physiological conditions. Preliminary in vivo studies show the high potential for these ultra-small ZnGa2 O4 :Cr(3+) nanoparticles to be used as in vivo optical nanotools as they emit without the need for in situ excitation and, thus, avoid the autofluorescence of tissues.
authors: Unité de Technologies Chimiques et Biologiques pour la Santé, CNRS, UMR 8258, Paris, 75270 cedex (France), Inserm, U1022, Paris, 75270 cedex (France), Université Paris Descartes, Sorbonne Paris Cité, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, 75270 cedex (France), ENSCP, Paris, 75231 cedex France, Chimie Paristech (France).
authors: Eliott
authors: E
authors: Teston
authors: Sophie
authors: S
authors: Richard
authors: Thomas
authors: T
authors: Maldiney
authors: Nicole
authors: N
authors: Lièvre
authors: Guillaume Yangshu
authors: GY
authors: Wang
authors: Laurence
authors: L
authors: Motte
authors: Cyrille
authors: C
authors: Richard
authors: Yoann
authors: Y
authors: Lalatonne
mesh_terms: D049449:Luminescence; D053758:Nanoparticles / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D044367:Phase Transition; D019265:Spectroscopy, Near-Infrared / Q000379:methods*
chemical_list: D010087:Oxides
keywords: in vivo imaging; infrared; luminescence; nanoparticles; oxides