title: Refinement of whole-genome multilocus sequence typing analysis by addressing gene paralogy.
abstract: We developed a user-friendly program, Genome Profiler (GeP), to refine whole-genome multilocus sequence typing analysis by addressing gene paralogy with conserved gene neighborhoods. In comparison to similar programs, GeP produced overall the best results in terms of accuracy and is thus a useful alternative to resolve relationships of bacterial isolates.
authors: Department of Food Hygiene and Environmental Health, University of Helsinki, Helsinki, Finland mirko.rossi@helsinki.fi ji.zhang@helsinki.fi.
authors: Ji
authors: J
authors: Zhang
authors: National Institute for Health and Welfare, Helsinki, Finland.
authors: Jani
authors: J
authors: Halkilahti
authors: Department of Food Hygiene and Environmental Health, University of Helsinki, Helsinki, Finland.
authors: Marja-Liisa
authors: ML
authors: Hänninen
authors: Department of Food Hygiene and Environmental Health, University of Helsinki, Helsinki, Finland mirko.rossi@helsinki.fi ji.zhang@helsinki.fi.
authors: Mirko
authors: M
authors: Rossi
mesh_terms: D000818:Animals; D001419:Bacteria / Q000145:classification* / Q000235:genetics*; D001431:Bacteriological Techniques / Q000379:methods*; D019295:Computational Biology / Q000379:methods*; D001330:Electronic Data Processing / Q000379:methods*; D006801:Humans; D058885:Multilocus Sequence Typing / Q000379:methods*