title: New quinolinone alkaloids from chestnut (Castanea crenata Sieb) honey.
abstract: Two new quinolinone alkaloids and 13 known compounds were isolated from chestnut (Castanea crenata Sieb) honey. Two new compounds were determined to be 3-dihydro-spiro[2(1H),3'(1'H)-diquinoline]-3',4,4'-trione (spirodiquinolinone) and 3-(2'-piperidine)-kynurenic acid. In addition, 2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one was identified for the first time from nature. In addition, 2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-one was newly identified from chestnut honey, although this compound has been synthesized before. The structures were determined by the NMR and electrospray ionization-mass spectroscopy (ESI-MS). Three compounds were qualified and quantitated in chestnut honey by selective multiple reaction monitoring (MRM) detection of LC-ESI-MS using the isolated compounds as external standards.
authors: Jeong-Yong
authors: JY
authors: Cho
authors: Sun-Hee
authors: SH
authors: Bae
authors: ‡Department of Agricultural Biology, National Academy of Agricultural Science, RDA, Suwon 441-100, Republic of Korea.
authors: Hye-Kyung
authors: HK
authors: Kim
authors: ‡Department of Agricultural Biology, National Academy of Agricultural Science, RDA, Suwon 441-100, Republic of Korea.
authors: Myeong-Lyeol
authors: ML
authors: Lee
authors: ‡Department of Agricultural Biology, National Academy of Agricultural Science, RDA, Suwon 441-100, Republic of Korea.
authors: Yong-Soo
authors: YS
authors: Choi
authors: §College of Natural Resources and Life Science, Dong-A University, Busan 604-714, Republic of Korea.
authors: Byung-Rae
authors: BR
authors: Jin
authors: Hyoung Jae
authors: HJ
authors: Lee
authors: Hang Yeon
authors: HY
authors: Jeong
authors: Yu Geon
authors: YG
authors: Lee
authors: Jae-Hak
authors: JH
authors: Moon
mesh_terms: D000470:Alkaloids / Q000032:analysis* / Q000737:chemistry; D029962:Fagaceae; D006722:Honey / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D015363:Quinolones / Q000032:analysis* / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D000470:Alkaloids; D015363:Quinolones
keywords: Castanea crenata; alkaloid; chestnut honey; kynurenic acid; quinolinone