title: [Ocular manifestations of acute T-cell lymphoblastic leukemia in hematological remission--a case report].
abstract: The paper presents a case of a 60 year-old female referred to the Department of Ophthalmology and Ocular Oncology, Medical College, Jagiellonian University in Krakow with the sudden severe vision deterioration in both eyes. The patient was treated for T-cell acute lymphoblastic leukemia at the local Department of Hematology, at that time she was considered to be in hematological remission. Based on findings of clinical examination and additional tests, the patient was diagnosed with leukemic infiltration of the retina and optic nerve with secondary retinal detachment. Systemic and intrathecal chemotherapy as well as local radiotherapy to both eyes were administered. Ocular manifestations of T-cell acute lymphoblastic leukemia may develop in patients in hematological remission. Standard management of leukemic infiltrates involving the retina, choroid and optic nerve includes the intrathecal chemotherapy and lo- cal radiotherapy. Such therapy caused regression and cicatrization of the ocular infiltrates, but did not improve visual acuity in the described patient.
authors: Maria
authors: M
authors: Siedlińska
authors: Izabella
authors: I
authors: Karska-Basta
authors: Dominika
authors: D
authors: Pagacz
authors: Marcin
authors: M
authors: Sobociński
authors: Bożena
authors: B
authors: Romanowska-Dixon
mesh_terms: D005260:Female; D006801:Humans; D017254:Leukemic Infiltration; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology* / Q000528:radiation effects; D009901:Optic Nerve Diseases / Q000473:pathology*; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography