title: Pregnancy outcome in proteinuria-onset and hypertension-onset preeclampsia.
abstract: OBJECTIVE
  To evaluate pregnancy outcome in preeclampsia (PE), according to the timing of onset of proteinuria and hypertension.
  
  
  METHODS
  Preeclamptic women were retrospectively divided into proteinuria-onset and hypertension-onset PE according to the first symptom. Maternal and perinatal outcome were assessed in both the groups.
  
  
  RESULTS
  One hundred and ninety five single pregnancies complicated by PE were included. According to the first symptom, they were divided into two groups: proteinuria-onset PE (n = 49, 25.1%) and hypertension-onset PE (n = 146, 74.9%). Pregnancy and neonatal outcome was significantly worse in proteinuria-onset PE.
  
  
  CONCLUSIONS
  Proteinuria-onset PE is associated with an increased risk of adverse pregnancy outcome than hypertension-onset PE.
authors: Department of Neurosciences, Reproductive and Dentistry Science, University Federico II , Naples , Italy.
authors: Laura
authors: L
authors: Sarno
authors: Giuseppe Maria
authors: GM
authors: Maruotti
authors: Gabriele
authors: G
authors: Saccone
authors: Angelo
authors: A
authors: Sirico
authors: Laura Letizia
authors: LL
authors: Mazzarelli
authors: Pasquale
authors: P
authors: Martinelli
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000175:diagnosis*; D007231:Infant, Newborn; D008297:Male; D011225:Pre-Eclampsia / Q000175:diagnosis*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011379:Prognosis; D011507:Proteinuria / Q000175:diagnosis*; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors
keywords: Hypertension; preeclampsia; pregnancy outcome; proteinuria.