title: L-FABP: A novel biomarker of kidney disease.
abstract: Human liver-type fatty acid-binding protein (hL-FABP), which is found in both the normal and the diseased human kidney, has been observed to bind free fatty acids. Recently, the predictive and prognostic value of L-FABP in kidney diseases has attracted considerable attention. Numerous studies have demonstrated that L-FABP is a promising biomarker of several kidney diseases, and it has also been shown to attenuate renal injury. We performed a literature review regarding the ability of L-FABP to identify patients at risk of developing kidney diseases, including acute kidney injury (AKI) and chronic kidney disease (CKD) and to protect the kidneys in the course of kidney disease.
authors: Department of Nephrology, Molecular Cell Lab for Kidney Disease, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, PR China.
authors: Yao
authors: Y
authors: Xu
authors: Department of Nephrology, Molecular Cell Lab for Kidney Disease, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, PR China.
authors: Yuanyuan
authors: Y
authors: Xie
authors: Department of Nephrology, Molecular Cell Lab for Kidney Disease, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, PR China.
authors: Xinghua
authors: X
authors: Shao
authors: Department of Nephrology, Molecular Cell Lab for Kidney Disease, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, PR China.
authors: Zhaohui
authors: Z
authors: Ni
authors: Department of Nephrology, Molecular Cell Lab for Kidney Disease, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, PR China. Electronic address: shan_mou@126.com.
authors: Shan
authors: S
authors: Mou
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D015415:Biomarkers / Q000378:metabolism; D003928:Diabetic Nephropathies / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D050556:Fatty Acid-Binding Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D015870:Gene Expression; D005921:Glomerulonephritis / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000378:metabolism / Q000473:pathology; D008958:Models, Molecular; D011379:Prognosis; D017433:Protein Structure, Secondary; D051436:Renal Insufficiency, Chronic / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D015427:Reperfusion Injury / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism / Q000473:pathology
chemical_list: D015415:Biomarkers; C493319:FABP1 protein, human; D050556:Fatty Acid-Binding Proteins
keywords: Acute kidney injury; Chronic kidney disease; Fatty acid; Liver-type fatty acid-binding protein