title: Trichosporon asahii infection after total knee arthroplasty: A case report and review of the literature.
abstract: Reports of fungal infection after total knee arthroplasty are extremely rare. In most reports, the infecting organism is a Candida species. The present report describes a case involving a 73-year-old immunocompetent woman who underwent total knee arthroplasty and presented one month later with signs of prosthetic infection. She underwent joint debridement and the fluid was sent for culture and sensitivity testing. The culture showed growth of Trichosporon asahii. The patient was administered intravenous and intra-articular injections of amphotericin B, followed by antifungal treatment with voriconazole for one year. At 26 months of follow-up, there was no evidence of infection and the patient was ambulating with a walker. To the authors' knowledge, the present case is the first report of T asahii infection following knee replacement. Early detection, prompt institution of the appropriate antibiotics and regular follow-up are recommended.
authors: Department of Orthopedics, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province; ; Department of Orthopedics, the First Affiliated Hospital of Baotou Medical College, Baotou, Inner Mongolia;
authors: Qiang
authors: Q
authors: Zuo
authors: Department of Orthopedics, the First Affiliated Hospital of Baotou Medical College, Baotou, Inner Mongolia;
authors: Lele
authors: L
authors: Dong
authors: Department of Orthopedics, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong Province;
authors: Weidong
authors: W
authors: Mu
authors: International Education College, Jiang Xi University of Traditional Chinese Medicine, Nanchang, Jiangxi Province;
authors: Lingyun
authors: L
authors: Zhou
authors: Clinical Laboratory, the First Affiliated Hospital of Baotou Medical College;
authors: Tongping
authors: T
authors: Hu
authors: Department of Oncology, the Third Affiliated Hospital of Inner Mongolia Medical College, Baotou, Inner Mongolia, People's Republic of China.
authors: Hua
authors: H
authors: Zhang
keywords: Fungal infection; Periprosthetic; Total knee arthroplasty; Trichosporon asahii