title: Population and forensic data for three sets of forensic genetic markers in four ethnic groups from Iran: Persians, Lurs, Kurds and Azeris.
abstract: A total of 255 individuals (Persians, Lurs, Kurds and Azeris) from Iran were typed for three sets of forensic genetic markers with the NGM SElect™, DIPplex(®) and Argus X-12 kits. Statistically significant deviations (P≤0.002) from Hardy-Weinberg expectations were observed for the insertion-deletion markers HLD97 and HLD93 after Holm-Šidák correction. Statistically significant (P<0.05) levels of linkage disequilibrium were observed between markers within two of the four studied X-chromosomal linkage groups. AMOVA analyses of the three sets of markers did not show population structure when the individuals were grouped according to their ethnic group. The Iranian population grouped closely to populations living geographically near to Iran based on pairwise FST distances. The matching probabilities ranged from 1 in 3.2×10(7) males by using haplotype frequencies of four X-chromosomal haplogroups to 1 in 3.4×10(21) individuals for the 16 autosomal STRs.
authors: Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark. Electronic address: lena.poulsen@sund.ku.dk.
authors: L
authors: L
authors: Poulsen
authors: Kawsar Human Genetics Research Center, 41 Majlesi St., Vali Asr St., Tehran, Iran.
authors: M Sharafi
authors: MS
authors: Farzad
authors: Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark.
authors: C
authors: C
authors: Børsting
authors: Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark.
authors: C
authors: C
authors: Tomas
authors: Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark.
authors: V
authors: V
authors: Pereira
authors: Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark.
authors: N
authors: N
authors: Morling
mesh_terms: D015415:Biomarkers / Q000097:blood; D004247:DNA / Q000097:blood / Q000235:genetics; D030541:Databases, Genetic; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D053803:Forensic Genetics / Q000379:methods*; D005819:Genetic Markers / Q000235:genetics*; D005828:Genetics, Population / Q000379:methods; D005838:Genotype; D006239:Haplotypes; D006801:Humans; D054643:INDEL Mutation; D007492:Iran; D008297:Male; D018895:Microsatellite Repeats
chemical_list: D015415:Biomarkers; D005819:Genetic Markers; D004247:DNA
keywords: Argus X-12; DIPplex(®); Forensic genetics; Iran; NGM SElect™