title: Deinococcus as new chassis for industrial biotechnology: biology, physiology and tools.
abstract: Deinococcus spp are among the most radiation-resistant micro-organisms that have been discovered. They show remarkable resistance to a range of damage caused by ionizing radiation, desiccation, UV radiation and oxidizing agents. Traditionally, Escherichia coli and Saccharomyces cerevisiae have been the two platforms of choice for engineering micro-organisms for biotechnological applications, because they are well understood and easy to work with. However, in recent years, researchers have begun using Deinococcus spp in biotechnologies and bioremediation due to their specific ability to grow and express novel engineered functions. More recently, the sequencing of several Deinococcus spp and comparative genomic analysis have provided new insight into the potential of this genus. Features such as the accumulation of genes encoding cell cleaning systems that eliminate organic and inorganic cell toxic components are widespread among Deinococcus spp. Other features such as the ability to degrade and metabolize sugars and polymeric sugars make Deinococcus spp. an attractive alternative for use in industrial biotechnology.
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: E
authors: E
authors: Gerber
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: R
authors: R
authors: Bernard
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: S
authors: S
authors: Castang
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: N
authors: N
authors: Chabot
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: F
authors: F
authors: Coze
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: A
authors: A
authors: Dreux-Zigha
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: E
authors: E
authors: Hauser
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: P
authors: P
authors: Hivin
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: P
authors: P
authors: Joseph
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: C
authors: C
authors: Lazarelli
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: G
authors: G
authors: Letellier
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: J
authors: J
authors: Olive
authors: Deinove, Cap Sigma/ZAC Euromédecine II, Grabels, France.
authors: J-P
authors: JP
authors: Leonetti
mesh_terms: D018441:Biofilms; D001709:Biotechnology; D002473:Cell Wall / Q000737:chemistry; D034301:Deinococcus / Q000166:cytology / Q000235:genetics* / Q000502:physiology; D007218:Industrial Microbiology / Q000295:instrumentation / Q000379:methods; D018384:Oxidative Stress
keywords: Deinococcus; biochemical engineering; biotechnology; extremophile; fermentation biotechnology