title: Determination of furfural and hydroxymethylfurfural from baby formula using headspace solid phase microextraction based on nanostructured polypyrrole fiber coupled with ion mobility spectrometry.
abstract: Furfural (Fu) and hydroxymethylfurfural (HMFu) are extracted using a dodecylbenzenesulfonate-doped polypyrrole coating as a fiber for headspace solid phase microextraction (HS-SPME) method in baby formula samples and detected using ion mobility spectrometry (IMS). Sample pH, salt effect, extraction time and temperature were investigated and optimized as effective parameters in HS-SPME. The calibration curves were linear in the range of 20-300 ng g(-1) (R(2)>0.99). Limits of detection for Fu and HMFu were 6 ng g(-1) and 5 ng g(-1), respectively. The RSD% of Fu and HMFu for five analyses was 4.4 and 4.9, respectively. The proposed method was successfully applied to determine of Fu and HMFu in the different baby formula samples with satisfactory result. The results were in agreement with those obtained using HPLC analysis. The HS-SPME-IMS is precise, selective and sensitive analytical method for determination of Fu and HMFu in baby formula samples, without any derivatization process.
authors: Department of Chemistry, Faculty of Sciences, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
authors: Mahdie
authors: M
authors: Kamalabadi
authors: Department of Chemistry, Faculty of Sciences, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran.
authors: Elham
authors: E
authors: Ghaemi
authors: Department of Food Science and Technology, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors: Abdorreza
authors: A
authors: Mohammadi
authors: Department of Chemistry, Faculty of Sciences, Tarbiat Modares University, P.O. Box 14115-175, Tehran, Iran. Electronic address: alizaden@modares.ac.ir.
authors: Naader
authors: N
authors: Alizadeh
mesh_terms: D002138:Calibration; D002851:Chromatography, High Pressure Liquid; D005506:Food Contamination / Q000032:analysis; D059022:Food Safety; D005662:Furaldehyde / Q000031:analogs & derivatives* / Q000032:analysis* / Q000302:isolation & purification*; D041943:Infant Formula / Q000737:chemistry*; D049329:Nanostructures; D011108:Polymers / Q000737:chemistry; D011758:Pyrroles / Q000737:chemistry; D052617:Solid Phase Microextraction / Q000295:instrumentation / Q000379:methods*; D013057:Spectrum Analysis / Q000379:methods*; D013696:Temperature
chemical_list: D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole; C008046:5-hydroxymethylfurfural; D005662:Furaldehyde
keywords: Baby formula; Furfural; Headspace solid phase microextraction; Hydroxymethylfurfural; Ion mobility spectrometry