title: Effects of treadmill exercise on muscle fibers in mice with steroid myopathy.
abstract: We studied the effect of treadmill exercise on muscle fibers in mice with experimental steroid myopathy. Frozen sections of the extensor digitorum longus (EDL) and soleus (SOL) muscles were stained with hematoxylin-eosin, and the muscle fiber diameters measured. In the EDL, muscle fiber diameters in the steroid groups decreased significantly compared with those in the control groups; moreover, muscle fiber diameters in the exercise groups increased significantly compared with those in the non-exercise groups, whereas the diameters in the SOL did not differ. We speculate that treadmill exercise may prevent corticosteroid-induced muscle fiber atrophy.
authors: Department of Physical Therapy, School of Allied Medical Sciences, Nagasaki University, Nagasaki 852-8520, Japan.
authors: M
authors: M
authors: Okita
authors: Department of Occupational Therapy, School of Allied Medical Sciences, Nagasaki University, Nagasaki 852-8520, Japan.
authors: T
authors: T
authors: Yoshimura
authors: Department of Health Science, Graduate School of Medical Science, Hiroshima University, Hiroshima 734-8551, Japan.
authors: J
authors: J
authors: Nakano
authors: Department of Physical Therapy, School of Allied Medical Sciences, Nagasaki University, Nagasaki 852-8520, Japan.
authors: M
authors: M
authors: Watabe
authors: Department of Rehabilitation, Yamashita Neuro Surgical Clinic, Fukuoka 830-0037, Japan.
authors: T
authors: T
authors: Nagai
authors: Department of Physical Therapy, School of Allied Medical Sciences, Nagasaki University, Nagasaki 852-8520, Japan.
authors: K
authors: K
authors: Kato
authors: The First Department of Internal Medicine, Nagasaki University School of Medicine, Nagasaki 852-8501, Japan.
authors: K
authors: K
authors: Eguchi
keywords: exercise; muscle fiber; steroid myopathy