title: Pituitary incidentalomas: analysis of a neuroradiological cohort.
abstract: OBJECTIVE
  Most pituitary lesions are detected during the investigation of symptoms associated with hormonal dysfunction and vision abnormalities. When the lesion is identified in an image performed for reasons not related to the tumor, the term incidentaloma applies. Our aim was to describe the diagnosis behind pituitary incidentalomas, patient characteristics and their follow up.
  
  
  METHODS
  We searched for the terms "pituitary", "hypophysis" and "incidentaloma" in the requisitions and reports of all CTs and MRIs performed between 1st September 2008 and 30th October 2013. We retrieved demographic data as well as information regarding presentation and follow-up.
  
  
  RESULTS
  We detected 71 pituitary incidentalomas, 3 in children/adolescents. In adult patients, mean age was 51.6 ± 18.46 years and 42 were female (61.8 %). The most frequent reason for imaging was headache (33.8 %). The image that first detected the incidentaloma was CT scan in 63.2 and 17.6 % patients presented symptoms that could have led to earlier diagnosis. Pituitary adenoma is the most prevalent lesion (n 48; 70.6 %), followed by Rathke's cleft cyst (n 9; 13.2 %). Hormonal evaluation revealed hypopituitarism in 14 patients and hypersecretion in 6: 5 prolactinomas and 1 somatotroph adenoma. Twenty-one (28.8 %) patients underwent surgery and there was no malignancy.
  
  
  CONCLUSIONS
  In concordance with available literature, adenomas are the most frequent incidentally found pituitary lesions. Hormonal dysfunction is quite prevalent, including symptomatic presentations, which suggests that there seems to be a low sensitivity for the diagnosis of pituitary disease.
authors: Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal. cme1983@gmail.com.|Faculty of Medicine, University of Porto, Porto, Portugal. cme1983@gmail.com.|Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal. cme1983@gmail.com.
authors: César
authors: C
authors: Esteves
authors: Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.|Faculty of Medicine, University of Porto, Porto, Portugal.|Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal.
authors: Celestino
authors: C
authors: Neves
authors: Department of Neuroradiology, Centro Hospitalar São João, Porto, Portugal.
authors: Luís
authors: L
authors: Augusto
authors: Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.|Faculty of Medicine, University of Porto, Porto, Portugal.|Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal.
authors: Joana
authors: J
authors: Menezes
authors: Department of Neurosurgery, Centro Hospitalar São João, Porto, Portugal.
authors: Josué
authors: J
authors: Pereira
authors: Department of Neuroradiology, Centro Hospitalar São João, Porto, Portugal.
authors: Irene
authors: I
authors: Bernardes
authors: Department of Neuroradiology, Centro Hospitalar São João, Porto, Portugal.
authors: José
authors: J
authors: Fonseca
authors: Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.|Faculty of Medicine, University of Porto, Porto, Portugal.|Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal.
authors: Davide
authors: D
authors: Carvalho
mesh_terms: D000328:Adult; D000368:Aged; D020863:Central Nervous System Cysts / Q000175:diagnosis / Q000000981:diagnostic imaging; D005260:Female; D049912:Growth Hormone-Secreting Pituitary Adenoma / Q000175:diagnosis / Q000000981:diagnostic imaging; D006261:Headache / Q000175:diagnosis / Q000000981:diagnostic imaging; D006801:Humans; D007018:Hypopituitarism / Q000175:diagnosis / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D015175:Prolactinoma / Q000175:diagnosis / Q000000981:diagnostic imaging; D011859:Radiography
keywords: Adenoma; Headache; Hormonal dysfunction; Incidentaloma; Pituitary