title: Involvement of Eyelid Pressure in Lid-Wiper Epitheliopathy.
abstract: OBJECTIVE
  To determine whether eyelid pressure is involved in the development of lid-wiper epitheliopathy (LWE).
  
  
  METHODS
  Study 1: The eyelid pressure was measured with a blepharo-tensiometer, and the degree of LWE was assessed in 79 eyes of 43 non-contact lens (CL) wearers. Study 2: The movements of the eyelids and displacement of the eyes during spontaneous blinking were photographed with a high-speed camera. The eyelid pressure was also measured in 34 normal eyes of 19 non-CL wearers who were not part of Study 1.
  
  
  RESULTS
  Study 1: Upper-LWE was detected in 24 of 79 eyes (30.4%), and no significant difference was detected in the eyelid pressure between any grade of upper-LWE. Lower-LWE was detected in 41 of 79 eyes (51.9%), and the eyelid pressure (27.9 ± 2.8 mmHg) in eyes with grade 3 LWE was significantly higher than that with grade 0 LWE (19.7 ± 1.3 mmHg; p < 0.05). Study 2: The lower eyelid pressure was significantly correlated with the length of the horizontal movement of the lower eyelids (p < 0.05) and also with the degree of posterior movement of the eye globe (p < 0.05).
  
  
  CONCLUSIONS
  The higher pressure from the eyelid may be one of the causes for the development of lower-LWE.
authors: a Department of Ophthalmology .
authors: Yasuaki
authors: Y
authors: Yamamoto
authors: a Department of Ophthalmology .|b Department of Stem Cell Biology , and.
authors: Atsushi
authors: A
authors: Shiraishi
authors: a Department of Ophthalmology .
authors: Yuri
authors: Y
authors: Sakane
authors: a Department of Ophthalmology .
authors: Kiyohiko
authors: K
authors: Ohta
authors: a Department of Ophthalmology .
authors: Masahiko
authors: M
authors: Yamaguchi
authors: a Department of Ophthalmology .|c Department of Infectious Diseases , Ehime University Graduate School of Medicine , Shitsukawa, Toon , Ehime , Japan.
authors: Yuichi
authors: Y
authors: Ohashi
mesh_terms: D001767:Blinking / Q000502:physiology*; D003228:Conjunctiva / Q000502:physiology*; D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation*; D004847:Epithelial Cells / Q000502:physiology*; D005133:Eye Movements / Q000502:physiology; D005143:Eyelids / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D010781:Photography; D011312:Pressure; D055815:Young Adult
keywords: Blepharo-tensiometer; eyelid pressure; lid-wiper epitheliopathy; lower eyelid; posterior movement of the eye globe