title: [A recurrent gastric cancer with peritoneal metastasis 15 years after distal gastrectomy successfully treated with S-1 and weekly intravenous and intraperitoneal injections of Paclitaxel].
abstract: Fifteen years after receiving a distal gastrectomy for advanced gastric cancer, a 70-year-old woman was admitted to our hospital because of abdominal fullness due to ascites. Although cytological examination showed adenocarcinoma cells in the fluid, no examination revealed the primary lesion. Peritoneal metastasis was detected via immunohistochemistry using the cell block technique. After chemotherapy failure (S-1 plus CDDP, weekly PTX, and S-1 plus DOC), the patient received S-1 and weekly intravenous and intraperitoneal injections of PTX. The ascites decreased, and she has been doing well. Our experience with this case suggests that S-1 and weekly intravenous and intraperitoneal injections of PTX is a promising means of treating gastric cancer with peritoneal metastasis.
authors: Dept. of Gastroenterology and Hepatology, Otsu Municipal Hospital.
authors: Naoto
authors: N
authors: Iwai
authors: Naoki
authors: N
authors: Wakabayashi
authors: Naoyuki
authors: N
authors: Matsumoto
authors: Yukihiro
authors: Y
authors: Morita
authors: Noriko
authors: N
authors: Tanaka
authors: Hiroyuki
authors: H
authors: Yoriki
authors: Kota
authors: K
authors: Fujii
authors: Ryusuke
authors: R
authors: Takada
authors: Hiroki
authors: H
authors: Takaya
authors: Akira
authors: A
authors: Masuzawa
authors: Shiro
authors: S
authors: Takami
authors: Keisho
authors: K
authors: Kataoka
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001201:Ascites; D004338:Drug Combinations; D005260:Female; D005743:Gastrectomy; D006801:Humans; D007262:Infusions, Intravenous; D007274:Injections, Intraperitoneal; D010094:Oxonic Acid / Q000008:administration & dosage; D017239:Paclitaxel / Q000008:administration & dosage; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary; D012008:Recurrence; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage; D013997:Time Factors
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D017239:Paclitaxel