title: Reward-based decision signals in parietal cortex are partially embodied.
abstract: Recordings in the lateral intraparietal area (LIP) reveal that parietal cortex encodes variables related to spatial decision-making, the selection of desirable targets in space. It has been unclear whether parietal cortex is involved in spatial decision-making in general, or whether specific parietal compartments subserve decisions made using specific actions. To test this, we engaged monkeys (Macaca mulatta) in a reward-based decision task in which they selected a target based on its desirability. The animals' choice behavior in this task followed the molar matching law, and in each trial was governed by the desirability of the choice targets. Critically, animals were instructed to make the choice using one of two actions: eye movements (saccades) and arm movements (reaches). We recorded the discharge activity of neurons in area LIP and the parietal reach region (PRR) of the parietal cortex. In line with previous studies, we found that both LIP and PRR encode a reward-based decision variable, the target desirability. Crucially, the target desirability was encoded in LIP at least twice as strongly when choices were made using saccades compared with reaches. In contrast, PRR encoded target desirability only for reaches and not for saccades. These data suggest that decisions can evolve in dedicated parietal circuits in the context of specific actions. This finding supports the hypothesis of an intentional representation of developing decisions in parietal cortex. Furthermore, the close link between the cognitive (decision-related) and bodily (action-related) processes presents a neural contribution to the theories of embodied cognition.
authors: Department of Anatomy and Neurobiology, Washington University School of Medicine, and Department of Biomedical Engineering, Washington University in St Louis, St Louis, Missouri 63130 jan@eye-hand.wustl.edu.
authors: Jan
authors: http://orcid.org/0000-0003-0527-5559
authors: J
authors: Kubanek
authors: Department of Anatomy and Neurobiology, Washington University School of Medicine, and Department of Biomedical Engineering, Washington University in St Louis, St Louis, Missouri 63130.
authors: Lawrence H
authors: http://orcid.org/0000-0002-3776-0199
authors: LH
authors: Snyder
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001132:Arm / Q000502:physiology; D003657:Decision Making / Q000502:physiology*; D005133:Eye Movements; D008253:Macaca mulatta; D008297:Male; D009474:Neurons / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology*; D010775:Photic Stimulation; D012201:Reward
keywords: LIP; decision making; eye (saccade); hand (reach); matching law; parietal reach region