title: Peripapillary choroidal thickness in nonarteritic anterior ischemic optic neuropathy.
abstract: OBJECTIVE
  To compare peripapillary choroidal thickness, macular thickness, and peripapillary retinal nerve fiber layer (RNFL) thickness between the affected eyes of patients with nonarteritic anterior ischemic optic neuropathy (NAION) and their unaffected eyes and the eyes of normal control subjects.
  
  
  METHODS
  Thirty-two eyes with NAION, 25 unaffected fellow eyes, and 25 normal control subjects met the inclusion criteria in this prospective comparative study at a single academic institution. Optic disc area, macular thickness, and RNFL thickness were evaluated at last follow up time using spectral-domain optical coherence tomography (OCT). Enhanced depth imaging OCT was obtained to evaluate peripapillary choroidal thickness.
  
  
  RESULTS
  Mean follow up time was 4.9 ±0.8 months and all data was collected from the last follow up. The mean optic disc area in NAION eyes and their unaffected fellow eyes were significantly smaller than normal control disc area measurements (P<0.001). Average PCT and all regional values were significantly greater in the NAION eyes and unaffected fellow eyes than in the control eyes (P=0.01). In all subjects, optic disc area was correlated with average PCT (r = -0.33, P = 0.002). In addition, RNFL thickness and macular thickness values were significantly lesser in the NAION eyes than in the unaffected fellow eyes and control eyes.
  
  
  CONCLUSIONS
  PCT is thicker in NAION eyes and unaffected fellow eyes than control eyes. Thick peripapillary choroid might contribute to the development of NAION.
authors: neuro-ophthalmology, Farabi Eye Institute, Tehran University of medical science, south kargar, Tehran, 13366, Iran.
authors: Masoud Aghsaei
authors: MA
authors: Fard
authors: Farabi Eye Center, Tehran University of Medical Science, Tehran, 13365, Iran.
authors: Parisa
authors: P
authors: Abdi
authors: Farabi Eye Hospital, Tehran University of Medical Science, Tehran, 13365, Iran.
authors: Abulfazl
authors: A
authors: Kasaei
authors: Rasht University of Medical Science, Rasht, 14565, Iran.
authors: Reza
authors: R
authors: Soltani Mogaddam
authors: Tehran University of Medical Science, Tehran, 13364, Iran.
authors: Marjan
authors: M
authors: Afzali
authors: Farabi Eye Center, Tehran University of Medical Sciences, Qazvin SQ, Tehran, 13336, Iran sasanimii@yahoo.com.
authors: Sasan
authors: S
authors: Moghimi