title: Rowell's Syndrome to ds-DNA Negative Lupus Nephritis: A Yet Unreported Progression.
abstract: Rowell's syndrome is now identified as a subtype of subacute lupus erythematosus (LE) with erythema multiforme-like skin lesions, positive serum rheumatoid factor, anti-Ro La positivity and speckled pattern of antinuclear antibodies. Here we describe a case of Rowell's syndrome in an 18-year-old female who was found to be ds-DNA negative, who later progressed to develop stage V lupus nephritis (LN) over a course of 4 months. Although extremely rare, most cases of LN are drug induced. Of only seven cases of non-drug induced LN with negative dsDNA, none had cutaneous involvement. Ours was a unique case of progression of Rowells syndrome to ds-DNA negative LN.
authors: Department of Skin and VD, MGM Medical College, Navi Mumbai, India.
authors: Mayur R
authors: MR
authors: Bhobe
authors: Department of Skin and VD, MGM Medical College, Navi Mumbai, India.
authors: Swagata
authors: S
authors: Tambe
authors: Department of Skin and VD, MGM Medical College, Navi Mumbai, India.
authors: Saurabh
authors: S
authors: Jindal
authors: Department of Skin and VD, MGM Medical College, Navi Mumbai, India.
authors: H R
authors: HR
authors: Jerajani
keywords: ds-DNA negative; lupus nephritis; rowell's syndrome