title: [Prevalence of vitamin d deficiency and insuffiency and associated factors in pregnant women of northern Spain].
abstract: OBJECTIVE
  The vitamin D deficiency during pregnancy has been associated with adverse events during pregnancy and the postnatal child development. In this study we examined plasma levels of vitamin D [25(OH)D3] and factors associated with plasma deficiency and insufficiency in pregnant women in northern Spain.
  
  
  METHODS
  We analyzed data from 453 pregnant women participating in the INMA-Asturias cohort in which was determined 25(OH)D3 by high resolution liquid chromatography.Dietary intake of vitamin D was estimated through a food frequency validated questionnaire. We estimated the prevalence of deficiency [25(OH)D3 <20 ng/ml] and insufficiency [20 to 29.9 ng / ml] of vitamin D and analyzed the distribution of 25(OH)D3 per month extraction and other factors.
  
  
  RESULTS
  The mean concentration of 25(OH)D3 was 27.7 ng/ml (range 6.4 to 69.5). 27.4% of pregnant women had deficient levels and 35.3% inssuficient. Levels of 25(OH)D3 were higher in the summer months (median 34.1 ng/ml). There was a higher percentage of deficiency in pregnant women with overweight/obesity (34.5%) and under 25 years (47.8%). The average daily intake of vitamin D was 5.48 mg / day (SD 2.82 range 1.09 to 32.52).Intake during the months of October to May was associated with levels of 25(OH)D3. 8.6% reported taking supplements of vitamin D.
  
  
  CONCLUSIONS
  We detected a high proportion of pregnant women with deficient or insufficient vitamin D levels, especially in the months of October to May, in pregnant women with overweight and obesity, and the youngest.
authors: Servicio de Pediatría, Hospital San Agustín, Avilés, Asturias.. crdehli@yahoo.es.
authors: Ana Cristina
authors: AC
authors: Rodríguez-Dehli
authors: Servicio de Pediatría, Hospital San Agustín, Avilés, Asturias. CIBER en Epidemiología y Salud Pública (CIBERESP).. crdehli@yahoo.es.
authors: Isolina
authors: I
authors: Riaño Galán
authors: Servicio de Medicina Preventiva, Universidad de Oviedo, Asturias. CIBER en Epidemiología y Salud Pública (CIBERESP).. crdehli@yahoo.es.
authors: Ana
authors: A
authors: Fernández-Somoano
authors: CIBER en Epidemiología y Salud Pública (CIBERESP). Departamento de Salud Pública, Universidad Miguel Hernández, Elche, Alicante.. crdehli@yahoo.es.
authors: Eva María
authors: EM
authors: Navarrete-Muñoz
authors: Unidad de Química Clínica, Salud Pública Laboratorio de Bilbao, Euskadi. España.. crdehli@yahoo.es.
authors: Mercedes
authors: M
authors: Espada
authors: CIBER en Epidemiología y Salud Pública (CIBERESP). Departamento de Salud Pública, Universidad Miguel Hernández, Elche, Alicante.. crdehli@yahoo.es.
authors: Jesús
authors: J
authors: Vioque
authors: Servicio de Medicina Preventiva, Universidad de Oviedo, Asturias. CIBER en Epidemiología y Salud Pública (CIBERESP).. crdehli@yahoo.es.
authors: Adonina
authors: A
authors: Tardón
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002112:Calcifediol / Q000097:blood; D015331:Cohort Studies; D005260:Female; D006801:Humans; D009765:Obesity / Q000150:complications / Q000453:epidemiology; D050177:Overweight / Q000150:complications / Q000453:epidemiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D037841:Pregnant People; D015995:Prevalence; D012621:Seasons; D013030:Spain / Q000453:epidemiology; D014807:Vitamin D / Q000097:blood; D014808:Vitamin D Deficiency / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D014807:Vitamin D; D002112:Calcifediol