title: Whole exome sequencing identifies the TNNI3K gene as a cause of familial conduction system disease and congenital junctional ectopic tachycardia.
authors: Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
authors: Yanwei
authors: Y
authors: Xi
authors: Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
authors: Christina
authors: C
authors: Honeywell
authors: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
authors: Dapeng
authors: D
authors: Zhang
authors: McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada.
authors: Jeremy
authors: J
authors: Schwartzentruber
authors: Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
authors: Chandree L
authors: CL
authors: Beaulieu
authors: McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
authors: Martine
authors: M
authors: Tetreault
authors: Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
authors: Taila
authors: T
authors: Hartley
authors: Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
authors: Jennifer
authors: J
authors: Marton
authors: Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
authors: Silvia M
authors: SM
authors: Vidal
authors: McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada; Department of Human Genetics, McGill University, Montreal, Quebec, Canada.
authors: Jacek
authors: J
authors: Majewski
authors: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
authors: L
authors: L
authors: Aravind
authors: Toronto General Hospital, Department of Cardiology, University of Toronto, Toronto, Ontario, Canada.
authors: Michael
authors: M
authors: Gollob
authors: Children's Hospital of Eastern Ontario Research Institute, University of Ottawa, Ottawa, Ontario, Canada; Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada. Electronic address: kboycott@cheo.on.ca.
authors: Kym M
authors: KM
authors: Boycott
authors: Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada. Electronic address: rgow@cheo.on.ca.
authors: Robert M
authors: RM
authors: Gow
mesh_terms: D002675:Child, Preschool; D004247:DNA / Q000235:genetics*; D004252:DNA Mutational Analysis; D059472:Exome; D005260:Female; D006329:Heart Conduction System / Q000002:abnormalities* / Q000503:physiopathology; D006801:Humans; D008297:Male; D009154:Mutation; D010375:Pedigree; D013613:Tachycardia, Ectopic Junctional / Q000151:congenital* / Q000235:genetics / Q000378:metabolism; D019210:Troponin I / Q000235:genetics* / Q000378:metabolism
chemical_list: C581522:TNNI1 protein, human; D019210:Troponin I; D004247:DNA
keywords: Exome sequencing; Junctional ectopic tachycardia; TNNI3K