title: The 2014 ACR annual meeting: a bird's eye view of autoimmunity in 2015.
abstract: Our understanding of the mechanisms leading to rheumatic diseases is growing at unprecedented pace thanks to the worldwide network of clinical and translational researchers who gather at major scientific meetings to share their progresses. Further, these meetings allow the contamination of unrelated research areas and thus the spreading of ideas, hypotheses, and research tools. The annual meeting of the American College of Rheumatology (ACR) serves this purpose by allowing thousands of rheumatologists, immunologists, health care professionals, and basic scientists to attend the same sessions and present their work. The 2014 ACR meeting was held in Boston, MA, and was attended by over 16,000 participants who had the opportunity to directly witness the presentation of over 3000 abstracts. As such is the case, a full attendance of all update opportunities was not feasible. To fill this gap we arbitrarily selected the abstracts the appeared most interesting in a few fields of interest and we herein discuss the presented data and their further implications. In particular, we were intrigued by research advances in biomarkers for rheumatic diseases, and by advances on Sjögren syndrome, neuropsychiatric systemic lupus erythematosus, fibromyalgia, and B cell mechanisms. While we are well aware of the numerous blind spots that are expected in this type of article, we submit that this is far from a comprehensive overview and refer to the abstract book for a more complete analysis of the presented abstracts.
authors: Division of Rheumatology and Clinical Immunology, Humanitas Research Hospital, Rozzano, Milan, Italy; BIOMETRA Department, University of Milan, Milan, Italy.
authors: Carlo
authors: C
authors: Selmi
authors: Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy.
authors: Luca
authors: L
authors: Cantarini
authors: Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel.
authors: Shaye
authors: S
authors: Kivity
authors: Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel.
authors: Amir
authors: A
authors: Dagaan
authors: Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel.
authors: Ora
authors: O
authors: Shovman
authors: Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel; Department of Medicine, Wolfson Medical Center, Holon, Israel.
authors: Gisele
authors: G
authors: Zandman-Goddard
authors: Rheumatology, Department of Medicine, Sapienza University of Rome, Rome, Italy.
authors: Carlo
authors: C
authors: Perricone
authors: Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel.
authors: Howard
authors: H
authors: Amital
authors: Division of Clinical Immunology, Bnai-Zion Medical Center, Haifa, Israel.
authors: Elias
authors: E
authors: Toubi
authors: Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Israel. Electronic address: shoenfel@post.tau.ac.il.
authors: Yehuda
authors: Y
authors: Shoenfeld
mesh_terms: D000818:Animals; D015551:Autoimmunity; D001402:B-Lymphocytes / Q000276:immunology; D015415:Biomarkers / Q000032:analysis; D001900:Boston; D003226:Congresses as Topic; D006801:Humans; D012216:Rheumatic Diseases / Q000276:immunology*; D012859:Sjogren's Syndrome / Q000276:immunology
chemical_list: D015415:Biomarkers
keywords: 14-3-3η; B cell depletion; BAFF; Biomarker; Calprotectin; Citrullinated peptide antibody; Citrullination; Connective tissue disease; Fibromyalgia; HMGCR; Leptin; MicroRNA; Mood disorder; Myositis; Neuropsychiatric lupus erythematosus; Prediction; Premature atherosclerosis; Sjogren; Smoking; Statins