title: Bone-adiposity cross-talk: implications for pediatric obesity. A narrative review of literature.
abstract: The rising prevalence of overweight and obesity among pediatric populations has become a major global concern. The objective of this review is to demonstrate potential interactions between the products released by fat tissue and the hormonal production of bone tissue in obese children and adolescents. Advancing the understanding of the complex interactions between adipocyte and osteocyte activities may contribute to the mechanistic understanding of the body's responses to weight loss during adolescence. This knowledge could also reveal any side effects encountered with these interventions. Currently, the concept of bone-adiposity crosstalk has not been fully elucidated, and the mechanisms remain controversial. Understanding the local interactions between the released products by fat tissue and hormones produced in bone tissue requires further investigations.
authors: Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), EA 3533, Clermont University, Blaise Pascal University, Clermont-Ferrand, France. e.chaplais@live.fr.|School of Exercise Science, Australian Catholic University, Strathfield campus, Locked Bag 2002, Strathfield, NSW, 2135, Australia. e.chaplais@live.fr.
authors: Elodie
authors: E
authors: Chaplais
authors: Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), EA 3533, Clermont University, Blaise Pascal University, Clermont-Ferrand, France.|CRNH-Auvergne, Clermont-Ferrand, France.
authors: David
authors: D
authors: Thivel
authors: School of Exercise Science, Australian Catholic University, Strathfield campus, Locked Bag 2002, Strathfield, NSW, 2135, Australia.
authors: David
authors: D
authors: Greene
authors: Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), EA 3533, Clermont University, Blaise Pascal University, Clermont-Ferrand, France.|School of Exercise Science, Australian Catholic University, Strathfield campus, Locked Bag 2002, Strathfield, NSW, 2135, Australia.|Occupational Medicine, University Hospital CHU G. Montpied, 63000, Clermont-Ferrand, France.
authors: Frederic
authors: F
authors: Dutheil
authors: Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), EA 3533, Clermont University, Blaise Pascal University, Clermont-Ferrand, France.|CRNH-Auvergne, Clermont-Ferrand, France.
authors: Pascale
authors: P
authors: Duche
authors: School of Exercise Science, Australian Catholic University, Strathfield campus, Locked Bag 2002, Strathfield, NSW, 2135, Australia.|School of Exercise Science, Australian Catholic University, Melbourne campus, Fitzroy MDC, Locked Bag 4115, Fitzroy, VIC, 3065, Australia.
authors: Geraldine
authors: G
authors: Naughton
authors: Laboratory of the Metabolic Adaptations to Exercise under Physiological and Pathological Conditions (AME2P), EA 3533, Clermont University, Blaise Pascal University, Clermont-Ferrand, France.|School of Exercise Science, Australian Catholic University, Strathfield campus, Locked Bag 2002, Strathfield, NSW, 2135, Australia.|CRNH-Auvergne, Clermont-Ferrand, France.
authors: Daniel
authors: D
authors: Courteix
mesh_terms: D017667:Adipocytes / Q000473:pathology; D050154:Adiposity; D000293:Adolescent; D006801:Humans; D009929:Organ Size; D063766:Pediatric Obesity / Q000473:pathology*; D015431:Weight Loss
keywords: Adipocyte; Adolescents; Obesity; Osteocyte