title: SWI enhances vein detection using gadolinium in multiple sclerosis.
abstract: Susceptibility weighted imaging (SWI) combined with the FLAIR sequence provides the ability to depict in vivo the perivenous location of inflammatory demyelinating lesions - one of the most specific pathologic features of multiple sclerosis (MS). In addition, in MS white matter (WM) lesions, gadolinium-based contrast media (CM) can increase vein signal loss on SWI. This report focuses on two cases of WM inflammatory lesions enhancing on SWI images after CM injection. In these lesions in fact the CM increased the contrast between the parenchyma and the central vein allowing as well, in one of the two cases, the detection of a vein not visible on the same SWI sequence acquired before CM injection.
authors: Department of Neurosciences, Drug Research, and Child's Health, University of Florence, Florence, Italy.
authors: Pietro
authors: P
authors: Maggi
authors: Health Physics Unit, Careggi University Hospital, Florence Italy.
authors: Lorenzo N
authors: LN
authors: Mazzoni
authors: Department of Neuroimaging, University of Florence, Florence, Italy.
authors: Marco
authors: M
authors: Moretti
authors: Department of Neurosciences, Drug Research, and Child's Health, University of Florence, Florence, Italy.
authors: Matteo
authors: M
authors: Grammatico
authors: Medical Imaging Department, Careggi University Hospital, Florence Italy.
authors: Stefano
authors: S
authors: Chiti
authors: Department of Neurosciences, Drug Research, and Child's Health, University of Florence, Florence, Italy.
authors: Luca
authors: L
authors: Massacesi
keywords: Central nervous system (CNS); brain/brain stem; inflammation; magnetic resonance imaging (MRI)