title: Easy to use plastic optical fiber-based biosensor for detection of butanal.
abstract: The final goal of this work is to achieve a selective detection of butanal by the realization of a simple, small-size and low cost experimental approach. To this end, a porcine odorant-binding protein was used in connection with surface plasmon resonance transduction in a plastic optical fiber tool for the selective detection of butanal by a competitive assay. This allows to reduce the cost and the size of the sensing device and it offers the possibility to design a "Lab-on-a-chip" platform. The obtained results showed that this system approach is able to selectively detect the presence of butanal in the concentration range from 20 μM to 1000 μM.
authors: Department of Industrial and Information Engineering, SUN, Aversa, Italy.
authors: Nunzio
authors: N
authors: Cennamo
authors: Institute of Protein Biochemistry, CNR, Napoli, Italy.
authors: Stefano
authors: S
authors: Di Giovanni
authors: Institute of Protein Biochemistry, CNR, Napoli, Italy.
authors: Antonio
authors: A
authors: Varriale
authors: Institute of Protein Biochemistry, CNR, Napoli, Italy.
authors: Maria
authors: M
authors: Staiano
authors: "O.M.Corbino" Institute of Acoustics and Sensors, Rome, Italy.
authors: Fabio
authors: F
authors: Di Pietrantonio
authors: Institute for Photonics and Nanotechnologies, CNR, Rome, Italy.
authors: Andrea
authors: A
authors: Notargiacomo
authors: Department of Industrial and Information Engineering, SUN, Aversa, Italy.
authors: Luigi
authors: L
authors: Zeni
authors: Institute of Protein Biochemistry, CNR, Napoli, Italy; Institute of Food Science, CNR, Avellino, Italy.
authors: Sabato
authors: S
authors: D'Auria
mesh_terms: D000447:Aldehydes / Q000032:analysis* / Q000737:chemistry; D000818:Animals; D015374:Biosensing Techniques / Q000379:methods*; D055100:Optical Fibers; D018035:Receptors, Odorant / Q000737:chemistry*; D020349:Surface Plasmon Resonance / Q000379:methods*; D034421:Sus scrofa
chemical_list: D000447:Aldehydes; D018035:Receptors, Odorant; C045648:odorant-binding protein; C018475:butyraldehyde