title: Ciliary vesicle formation: a prelude to ciliogenesis.
abstract: Reporting recently in Nature Cell Biology, Lu et al. (2015) identify two Eps15-homology-domain-containing proteins as critical effectors of ciliary vesicle formation, an early event in ciliogenesis. Functional dissection reveals that one of them works to convert small vesicles associated with mother centriole distal appendages into a larger ciliary vesicle.
authors: Department of Biochemistry and Biophysics, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: laura.yee@ucsf.edu.
authors: Laura E
authors: LE
authors: Yee
authors: Department of Biochemistry and Biophysics, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: jeremy.reiter@ucsf.edu.
authors: Jeremy F
authors: JF
authors: Reiter
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000235:genetics*; D002923:Cilia / Q000378:metabolism*; D004847:Epithelial Cells / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D022161:Transport Vesicles / Q000378:metabolism*; D033921:Vesicular Transport Proteins / Q000235:genetics*
chemical_list: D002352:Carrier Proteins; D033921:Vesicular Transport Proteins