title: Helicobacter apodemus sp. nov., a new Helicobacter species identified from the gastrointestinal tract of striped field mice in Korea.
abstract: A novel Helicobacter species was identified from the gastrointestinal tract of the Korean striped field mouse (Apodemus agrarius). Biochemical testing, ultrastructure characterization, and 16S rRNA gene sequence analysis suggested that this bacterium represents a distinct taxon. The bacterium was positive for urease activity, susceptible to cephalothin and nalidixic acid, and weakly positive for oxidase and catalase activity. Electron microscopy revealed that the bacterium has spirally curved rod morphology with singular bipolar nonsheathed flagella. Genotypically, the isolated bacterial strains (YMRC 000215, YMRC 000216, and YMRC 000419) were most closely related to a reference strain of Helicobacter mesocricetorum (97.25%, 97.32%, and 97.03% 16S rRNA sequence similarities, respectively). The 16S rRNA sequences of these strains were deposited into GenBank under accession numbers AF284754, AY009129, and AY009130, respectively. We propose the name Helicobacter apodemus for this novel species.
authors: Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BIO-MAX Institute, Program for Cancer Biology, and Interdisciplinary Program for Bioinformatics, BK21Plus Program fo.|Incheon International Airport Imported Food Inspection Center, Gyeongin Regional Food and Drug Administration, Ministry of Food and Drug Safety, Incheon 22382, Korea.
authors: Woo Jin
authors: WJ
authors: Jeon
authors: Laboratory of Veterinary Public Health, College of Veterinary Medicine, BIO-MAX Institute, Program for Cancer Biology, and Interdisciplinary Program for Bioinformatics, BK21Plus Program for Creative.
authors: Hee-Jin
authors: HJ
authors: Dong
authors: Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BIO-MAX Institute, Program for Cancer Biology, and Interdisciplinary Program for Bioinformatics, BK21Plus Program fo.
authors: Jae Hoon
authors: JH
authors: Shin
authors: Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BIO-MAX Institute, Program for Cancer Biology, and Interdisciplinary Program for Bioinformatics, BK21Plus Program fo.
authors: Il Yong
authors: IY
authors: Kim
authors: Laboratory of Veterinary Public Health, College of Veterinary Medicine, BIO-MAX Institute, Program for Cancer Biology, and Interdisciplinary Program for Bioinformatics, BK21Plus Program for Creative.
authors: Hungwui
authors: H
authors: Ho
authors: College of Pharmacy, Gachon University, Incheon 21936, Korea.
authors: Seung Hyun
authors: SH
authors: Oh
authors: College of Veterinary Medicine, Jeju National University, Jeju 63241, Korea.
authors: Young Min
authors: YM
authors: Yoon
authors: College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
authors: Yang-Kyu
authors: YK
authors: Choi
authors: Department of Medical Genetics, College of Medicine, Hallym University, Chuncheon 24252, Korea.
authors: Jun Gyo
authors: JG
authors: Suh
authors: Biomedical Mouse Resource Center, Korea Research Institute for Bioscience and Biotechnology, Ochang 34141, Korea.
authors: Ki-Hoan
authors: KH
authors: Nam
authors: Biomedical Mouse Resource Center, Korea Research Institute for Bioscience and Biotechnology, Ochang 34141, Korea.
authors: Hyoung-Chin
authors: HC
authors: Kim
authors: Laboratory of Veterinary Public Health, College of Veterinary Medicine, BIO-MAX Institute, Program for Cancer Biology, and Interdisciplinary Program for Bioinformatics, BK21Plus Program for Creative.
authors: Seongbeom
authors: S
authors: Cho
authors: Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, BIO-MAX Institute, Program for Cancer Biology, and Interdisciplinary Program for Bioinformatics, BK21Plus Program fo.
authors: Je Kyung
authors: JK
authors: Seong
mesh_terms: D000818:Animals; D004269:DNA, Bacterial / Q000235:genetics / Q000378:metabolism; D005260:Female; D041981:Gastrointestinal Tract / Q000382:microbiology; D016998:Helicobacter / Q000145:classification* / Q000235:genetics / Q000502:physiology* / Q000648:ultrastructure; D016481:Helicobacter Infections / Q000382:microbiology / Q000662:veterinary*; D008297:Male; D046529:Microscopy, Electron, Transmission / Q000662:veterinary; D008969:Molecular Sequence Data; D051189:Murinae; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics / Q000378:metabolism; D056910:Republic of Korea; D012376:Rodent Diseases / Q000382:microbiology*
chemical_list: D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S
keywords: 16S rRNA; Apodemus agrarius; Helicobacter apodemus; striped field mouse