title: PhI(OAc)2 mediated decarboxylative sulfonylation of β-aryl-α,β-unsaturated carboxylic acids: a synthesis of (E)-vinyl sulfones.
abstract: A highly efficient metal-free decarboxylative sulfonylation protocol for the preparation of (E)-vinyl sulfones from of β-aryl-α,β-unsaturated carboxylic acids using sodium sulfinates and (diacetoxyiodo)benzene (PhI(OAc)2) was developed. This strategy offers a simple and expedient synthesis of (E)-vinyl sulfones bearing a wide variety of functional groups. A radical-based pathway has been proposed for this decarboxylative sulfonylation reaction.
authors: Department of Chemistry and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand. chutima.kon@mahidol.ac.th.
authors: Praewpan
authors: P
authors: Katrun
authors: Sornsiri
authors: S
authors: Hlekhlai
authors: Jatuporn
authors: J
authors: Meesin
authors: Manat
authors: M
authors: Pohmakotr
authors: Vichai
authors: V
authors: Reutrakul
authors: Thaworn
authors: T
authors: Jaipetch
authors: Darunee
authors: D
authors: Soorukram
authors: Chutima
authors: C
authors: Kuhakarn