title: Symmetrical and Thermodynamic Properties of Phenotypic Graphs of Amino Acids Encoded by the Primeval RNY Code.
abstract: The 12 different types of graphs of the 8 amino acids encoded by the presumably primeval RNY code are derived. The symmetry groups of these graphs are analyzed and coincide with the corresponding values of polar requirement for each amino acid. The symmetry groups at the codon level are partially carried over as a group or subgroup at the amino acid level. Measures of centrality of the 12 graphs indicate that all amino acids were equally relevant irrespective of its chronological order of its appearance. The elimination of any amino acid would be strongly selected against and therefore the genetic code at this stage was already frozen.
authors: Theoretical Biology Group, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, México, D.F., 04510, Mexico, marcojose@biomedicas.unam.mx.
authors: Marco V
authors: MV
authors: José
authors: Gabriel S
authors: GS
authors: Zamudio
authors: Miryam
authors: M
authors: Palacios-Pérez
authors: Juan R
authors: JR
authors: Bobadilla
authors: Sávio Torres
authors: ST
authors: de Farías
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D003062:Codon / Q000737:chemistry*; D019418:Evolution, Chemical; D008956:Models, Chemical; D013816:Thermodynamics
chemical_list: D000596:Amino Acids; D003062:Codon