title: The stability and degradation kinetics of Sulforaphene in microcapsules based on several biopolymers via spray drying.
abstract: Sulforaphene (SFE) was extracted from the radish seeds and the purity of SFE extracted by our laboratory was 95%. It is well known that SFE can prevent cancers. It is also known that SFE is unstable to heat. To overcome the problem, SFE microcapsules using natural biopolymers were prepared by spray drying. The results indicated that SFE microcapsules using hydroxypropyl-β-cyclodextrin (HP-β-CD), maltodextrin (MD) and isolated soybean protein (SPI) as wall materials could effectively improve its stability against heat, especially SFE-loaded HP-β-CD and MD microcapsules. The amount of SFE in the microcapsules was found 20% higher than that of the non-encapsulated SFE under 90 °C in 168 h. Our finding suggested that the rate of degradation of the non-encapsulated and encapsulated SFE with HP-β-CD, MD and SPI followed the first-order kinetics. The speed of the degradation of the encapsulated SFE in biopolymers increased from SFE with HP-β-CD, to SFE with MD, and to SFE-SPI. The non-encapsulated SFE degrades fastest.
authors: State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Mailbox No. 75, Science and Technology, No. 15 North Third Ring East Road, Chaoyang District, Beijing 100029, PR China.
authors: Guifang
authors: G
authors: Tian
authors: State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Mailbox No. 75, Science and Technology, No. 15 North Third Ring East Road, Chaoyang District, Beijing 100029, PR China.
authors: Yuan
authors: Y
authors: Li
authors: State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Mailbox No. 75, Science and Technology, No. 15 North Third Ring East Road, Chaoyang District, Beijing 100029, PR China. Electronic address: yuanqp@mail.buct.edu.cn.
authors: Qipeng
authors: Q
authors: Yuan
authors: State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Mailbox No. 75, Science and Technology, No. 15 North Third Ring East Road, Chaoyang District, Beijing 100029, PR China.
authors: Li
authors: L
authors: Cheng
authors: State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Mailbox No. 75, Science and Technology, No. 15 North Third Ring East Road, Chaoyang District, Beijing 100029, PR China.
authors: Pengqun
authors: P
authors: Kuang
authors: State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Mailbox No. 75, Science and Technology, No. 15 North Third Ring East Road, Chaoyang District, Beijing 100029, PR China.
authors: Pingwah
authors: P
authors: Tang
mesh_terms: D001704:Biopolymers / Q000737:chemistry*; D002214:Capsules; D003890:Desiccation; D004337:Drug Carriers / Q000737:chemistry*; D004355:Drug Stability; D006358:Hot Temperature; D017879:Isothiocyanates / Q000737:chemistry*; D007700:Kinetics
chemical_list: D001704:Biopolymers; D002214:Capsules; D004337:Drug Carriers; D017879:Isothiocyanates; C473643:sulphoraphene
keywords: Degradation kinetics; Microcapsules; Spray drying; Stability; Sulforaphene