title: [Immunomodulators for the prevention and treatment of acute respiratory infections: efficacy of azoximer bromide].
abstract: The review gives the results of a many-sided study of the basic properties of the therapeutic molecule of azoximer bromide (polyoxidonium). It analyzes our experience with the immunomodulator used to treat acute respiratory infections. Polyoxidonium has marked immunomodulatory (including interferon-producing) activity and a nonspecific protective effect against a broad range of pathogens, which is based on the regulation of systemic immunity rather than the direct inhibition of microorganisms. In addition, the drug has antitoxic and antioxidant properties. Azoximer bromide is used in combination with etiotropic therapy in the acute phase of disease and as monotherapy for rehabilitation or immunoprophylaxis of respiratory infections.
authors: V A
authors: VA
authors: Bulgakova
mesh_terms: D000328:Adult; D002648:Child; D006801:Humans; D007155:Immunologic Factors / Q000008:administration & dosage / Q000494:pharmacology*; D010879:Piperazines / Q000008:administration & dosage / Q000494:pharmacology*; D011108:Polymers / Q000008:administration & dosage / Q000494:pharmacology*; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000517:prevention & control*
chemical_list: D007155:Immunologic Factors; D010879:Piperazines; D011108:Polymers; C540909:azoximer bromide