title: Combination of flecainide and propranolol for congenital junctional ectopic tachycardia.
abstract: Congenital junctional ectopic tachycardia is a rare tachyarrhythmia with high mortality. A pharmacological approach in early infancy is regarded as the first-line therapeutic option. Pharmacologically, amiodarone alone or in combination with other drugs is the most commonly reported effective agent for congenital junctional ectopic tachycardia, but it has many adverse effects. Here we report the case of a 40-day-old infant. The clinical course suggests that combined oral flecainide and propranolol is an effective alternative therapy for early infants. Esophageal lead electrocardiography may give a clear diagnosis of junctional ectopic tachycardia.
authors: Department of Pediatrics, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan.
authors: Tomohiko
authors: T
authors: Imamura
authors: Department of Pediatrics, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan.
authors: Yuji
authors: Y
authors: Tanaka
authors: Department of Pediatrics, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan.
authors: Yumiko
authors: Y
authors: Ninomiya
authors: Department of Pediatrics, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan.
authors: Masao
authors: M
authors: Yoshinaga
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D005424:Flecainide / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D008297:Male; D011433:Propranolol / Q000008:administration & dosage*; D013613:Tachycardia, Ectopic Junctional / Q000188:drug therapy*
chemical_list: D000889:Anti-Arrhythmia Agents; D011433:Propranolol; D005424:Flecainide
keywords: amiodarone; congenital junctional ectopic tachycardia; esophageal lead; propranolol; tachyarrhythmia