title: Prebiotic Potential of Xylooligosaccharides Derived from Corn Cobs and Their In Vitro Antioxidant Activity When Combined with Lactobacillus.
abstract: In the present work, the in vitro prebiotic activity of xylooligosaccharides (XOS) derived from corn cobs combined with Lactobacillus plantarum, a probiotic microorganism, was determined. These probiotics exhibited different growth characteristics depending on strain specificity. L. plantarum S2 cells were denser and their growth rates were higher when cultured on XOS. Acetate was found to be the major short-chain fatty acid produced as the end-product of fermentation, and its amount varied from 1.50 to 1.78 mg/ml. The antimicrobial activity of XOS combined with L. plantarum S2 was determined against gastrointestinal pathogens. The results showed that XOS proved to be an effective substrate, enhancing antimicrobial activity for L. plantarum S2. In vivo evaluation of the influence of XOS and L. plantarum S2, used both alone and together, on the intestinal microbiota in a mouse model showed that XOS combined with L. plantarum S2 could increase the viable lactobacilli and bifidobacteria in mice feces and decrease the viable Enterococcus, Enterobacter, and Clostridia spp. Furthermore, in the in vitro antioxidant assay, XOS combined with L. plantarum S2 possessed significant 2,2-diphenyl-1- picrylhydrazyl, 2,2'-azino-bis, and superoxide anion radical-scavenging activities, and the combinations showed better antioxidant activity than either XOS or L. plantarum S2 alone.
authors: School of Pharmaceutical Sciences, Jilin University, Changchun 130021, P.R. China.|The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun 130021, P.R. China.
authors: Xiuhua
authors: X
authors: Yu
authors: School of Pharmaceutical Sciences, Jilin University, Changchun 130021, P.R. China.
authors: Jianyuan
authors: J
authors: Yin
authors: The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun 130021, P.R. China.
authors: Lin
authors: L
authors: Li
authors: Institute of Agro-food Technology, Jilin Academy of Agricultural Sciences, Changchun 130033, P.R. China.
authors: Chang
authors: C
authors: Luan
authors: Institute of Agro-food Technology, Jilin Academy of Agricultural Sciences, Changchun 130033, P.R. China.
authors: Jian
authors: J
authors: Zhang
authors: School of Pharmaceutical Sciences, Jilin University, Changchun 130021, P.R. China.
authors: Chunfang
authors: C
authors: Zhao
authors: Institute of Agro-food Technology, Jilin Academy of Agricultural Sciences, Changchun 130033, P.R. China.
authors: Shengyu
authors: S
authors: Li
mesh_terms: D000085:Acetates / Q000032:analysis; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000378:metabolism*; D005243:Feces / Q000382:microbiology; D005285:Fermentation; D000069196:Gastrointestinal Microbiome; D005965:Glucuronates / Q000302:isolation & purification / Q000378:metabolism*; D048191:Lactiplantibacillus plantarum / Q000254:growth & development* / Q000378:metabolism*; D051379:Mice; D009844:Oligosaccharides / Q000302:isolation & purification / Q000378:metabolism*; D056692:Prebiotics / Q000008:administration & dosage; D019936:Probiotics / Q000008:administration & dosage; D003313:Zea mays / Q000737:chemistry*
chemical_list: D000085:Acetates; D000975:Antioxidants; D005965:Glucuronates; D009844:Oligosaccharides; D056692:Prebiotics; C570991:xylooligosaccharide
keywords: Lactobacillus plantarum; antioxidant activity; prebiotic; probiotic; xylooligosaccharide