title: The potential long-term effect of previous schistosome infection reduces the risk of metabolic syndrome among Chinese men.
abstract: The association between potential long-term effects of previous schistosome infection (PSI) and the development of metabolic syndrome remains unknown. Therefore, we aimed to evaluate the association between them. Participants were from regions which were all reportedly heavily endemic for S. japonicum in China 40 years ago. One thousand five hundred and ninety-seven men were enrolled. Among these, 465 patients with PSI were selected as study subjects and 1132 subjects served as controls. We found PSI significantly correlated with lower prevalences of metabolic syndrome and its components, including central obesity, hypertriglyceridemia and low high-density lipoprotein cholesterol, which indicates that the potential long-term effects of PSI may reduce the risk of metabolic syndrome. However, further studies are needed to investigate the protective immune effects of PSI.
authors: Wuxi No. 2 People's Hospital Affiliated to Nanjing Medical University, Wuxi City, Jiangsu Province, China.
authors: S-W
authors: SW
authors: Shen
authors: Jiangsu Provincial Taihu Cadre's Sanatorium of Jiangsu Provincial People's Hospital Group, Wuxi City, Jiangsu Province, China.
authors: Y
authors: Y
authors: Lu
authors: Jiangsu Provincial Taihu Cadre's Sanatorium of Jiangsu Provincial People's Hospital Group, Wuxi City, Jiangsu Province, China.
authors: F
authors: F
authors: Li
authors: Jiangsu Provincial Taihu Cadre's Sanatorium of Jiangsu Provincial People's Hospital Group, Wuxi City, Jiangsu Province, China.
authors: Z-H
authors: ZH
authors: Shen
authors: Jiangsu Institute of Parasitic Diseases, Wuxi City, Jiangsu Province, China.
authors: M
authors: M
authors: Xu
authors: Wuxi No. 2 People's Hospital Affiliated to Nanjing Medical University, Wuxi City, Jiangsu Province, China.
authors: W-F
authors: WF
authors: Yao
authors: Jiangsu Provincial Taihu Cadre's Sanatorium of Jiangsu Provincial People's Hospital Group, Wuxi City, Jiangsu Province, China.
authors: Y-B
authors: YB
authors: Feng
authors: Jiangsu Provincial Taihu Cadre's Sanatorium of Jiangsu Provincial People's Hospital Group, Wuxi City, Jiangsu Province, China.
authors: J-T
authors: JT
authors: Yun
authors: Wuxi No. 2 People's Hospital Affiliated to Nanjing Medical University, Wuxi City, Jiangsu Province, China.
authors: Y-P
authors: YP
authors: Wang
authors: Jiangsu Provincial Taihu Cadre's Sanatorium of Jiangsu Provincial People's Hospital Group, Wuxi City, Jiangsu Province, China.
authors: W
authors: W
authors: Ling
authors: Jiangsu Provincial Taihu Cadre's Sanatorium of Jiangsu Provincial People's Hospital Group, Wuxi City, Jiangsu Province, China.
authors: H-J
authors: HJ
authors: Qi
authors: Jiangsu Provincial Taihu Cadre's Sanatorium of Jiangsu Provincial People's Hospital Group, Wuxi City, Jiangsu Province, China.
authors: D-X
authors: DX
authors: Tong
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002681:China / Q000453:epidemiology; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence; D012549:Schistosoma japonicum / Q000276:immunology* / Q000472:pathogenicity; D012552:Schistosomiasis / Q000453:epidemiology* / Q000276:immunology; D011795:Surveys and Questionnaires; D013995:Time
chemical_list: D008075:Lipoproteins, HDL
keywords: men; metabolic syndrome; negative regulation of immune response; previous schistosome infection