title: Photoresponsive molecularly imprinted hydrogel casting membrane for the determination of trace tetracycline in milk.
abstract: This study aimed to develop a photoresponsive molecularly imprinted hydrogel (MIH) casting membrane for the determination of trace tetracycline (TC) in milk. This MIH casting membrane combined the specificity of MIHs, the photoresponsive properties of azobenzene, and the portable properties of a membrane. Photoresponsive TC-imprinted MIHs were initially fabricated and then cast on sodium dodecyl sulfonate polyacrylamide gel. After TC removal, a photoresponsive MIH casting membrane was obtained. The photoresponsive properties of the MIH casting membrane were robust, and no obvious photodegradation was observed after 20 cycles. The MIH casting membrane displayed specific affinity to TC upon alternate irradiation at 365 and 440 nm; it could quantitatively uptake and release TC. The TC concentration (0.0-2.0 × 10(-4) mol l(-1)) in aqueous solution displayed a linear relationship with the photoisomerization rate constant of azobenzene within the MIH casting membrane. As such, a quick detection method for trace TC in aqueous foodstuff samples was established. The recovery of this method for TC in milk was investigated with a simple pretreatment of milk, and a high recovery of 100.54-106.35% was obtained. Therefore, the fabricated membrane can be used as a portable molecular sensor that can be easily recycled.
authors: The Key Laboratory of Applied Chemistry of Chongqing Municipality, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
authors: Qiang
authors: Q
authors: Wang
authors: The Key Laboratory of Applied Chemistry of Chongqing Municipality, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
authors: Zhen
authors: Z
authors: Lv
authors: The Key Laboratory of Applied Chemistry of Chongqing Municipality, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
authors: Qian
authors: Q
authors: Tang
authors: The Key Laboratory of Applied Chemistry of Chongqing Municipality, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
authors: Cheng-Bin
authors: CB
authors: Gong
authors: Department of Biology and Chemistry, City University of Hong Kong, Hong Kong, China.
authors: Michael Hon Wah
authors: MH
authors: Lam
authors: The Key Laboratory of Applied Chemistry of Chongqing Municipality, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
authors: Xue-Bing
authors: XB
authors: Ma
authors: Department of Science and Environmental Studies, The Hong Kong Institute of Education, Hong Kong, China.
authors: Cheuk-Fai
authors: CF
authors: Chow
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis*; D020100:Hydrogels / Q000737:chemistry*; D008567:Membranes, Artificial; D008892:Milk / Q000737:chemistry*; D054802:Molecular Imprinting; D015394:Molecular Structure; D055668:Photochemical Processes; D013752:Tetracycline / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; D020100:Hydrogels; D008567:Membranes, Artificial; D013752:Tetracycline
keywords: 4-[(4-methacryloyloxy)phenylazo] benzenesulfonic acid; molecularly imprinted hydrogels; photoresponsive MIHs casting membrane; tetracycline antibiotics