title: Development of monoclonal antibodies in China: overview and prospects.
abstract: Monoclonal antibodies (mAbs) have become increasingly important as human therapeutic agents. Yet, current research concentrates on technology itself and pays attention to developed countries. This paper aims to provide a comprehensive review of mAbs development in China through systematic analysis of drug registry, patent applications, clinical trials, academic publication, and ongoing R&D projects. The trends in therapeutic areas and industrialization process are also highlighted. Development and research trends of mAbs are analyzed to provide a future perspective of mAbs as therapeutic agents in China.
authors: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau.
authors: Mao-Yu
authors: MY
authors: Zhang
authors: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau.
authors: Jin-Jian
authors: JJ
authors: Lu
authors: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau.
authors: Liang
authors: L
authors: Wang
authors: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau.
authors: Zi-Chao
authors: ZC
authors: Gao
authors: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau.
authors: Hao
authors: 0000-0001-9441-106X
authors: H
authors: Hu
authors: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau.
authors: Carolina Oi Lam
authors: CO
authors: Ung
authors: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau.
authors: Yi-Tao
authors: YT
authors: Wang
mesh_terms: D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D002681:China; D002986:Clinical Trials as Topic; D006801:Humans; D015202:Protein Engineering / Q000379:methods*; D011642:Publications
chemical_list: D000911:Antibodies, Monoclonal