title: Surgical treatment of the osteoporotic spine with bone cement-injectable cannulated pedicle screw fixation: technical description and preliminary application in 43 patients.
abstract: OBJECTIVE
  To describe a new approach for the application of polymethylmethacrylate augmentation of bone cement-injectable cannulated pedicle screws.
  
  
  METHODS
  Between June 2010 and February 2013, 43 patients with degenerative spinal disease and osteoporosis (T-score <-2.5) underwent lumbar fusion using cement-injectable cannulated pedicle screws. Clinical outcomes were evaluated using a Visual Analog Scale and the Oswestry Disability Index. Patients were given radiographic follow-up examinations after 3, 6, and 12 months and once per year thereafter.
  
  
  RESULTS
  All patients were followed for a mean of 15.7 ± 5.6 months (range, 6 to 35 months). The Visual Analog Scale and Oswestry Disability Index scores showed a significant reduction in back pain (p = 0.018) and an improvement in lower extremity function (p = 0.025) in patients who underwent lumbar fusion using the novel screw. Intraoperative cement leakage occurred in four patients, but no neurological complications were observed. Radiological observation indicated no loosening or pulling out of the novel screw, and bone fusion was excellent.
  
  
  CONCLUSIONS
  The described polymethylmethacrylate augmentation technique using bone cement-injectable cannulated pedicle screws can reduce pain and improve spinal dysfunction in osteoporotic patients undergoing osteoporotic spine surgery.
authors: Southwest Hospital, National & Regional United Engineering Laboratory of Tissue Engineering, Department of Orthopaedics, The Third Military Medical University, Chongqing, China.
authors: Fei
authors: F
authors: Dai
authors: Department of Spine Surgery, Daping Hospital, The Third Military Medical University, Chongqing, China.
authors: Yaoyao
authors: Y
authors: Liu
authors: Southwest Hospital, National & Regional United Engineering Laboratory of Tissue Engineering, Department of Orthopaedics, The Third Military Medical University, Chongqing, China.
authors: Fei
authors: F
authors: Zhang
authors: Southwest Hospital, National & Regional United Engineering Laboratory of Tissue Engineering, Department of Orthopaedics, The Third Military Medical University, Chongqing, China.
authors: Dong
authors: D
authors: Sun
authors: Southwest Hospital, National & Regional United Engineering Laboratory of Tissue Engineering, Department of Orthopaedics, The Third Military Medical University, Chongqing, China.
authors: Fei
authors: F
authors: Luo
authors: Southwest Hospital, National & Regional United Engineering Laboratory of Tissue Engineering, Department of Orthopaedics, The Third Military Medical University, Chongqing, China.
authors: Zehua
authors: Z
authors: Zhang
authors: Southwest Hospital, National & Regional United Engineering Laboratory of Tissue Engineering, Department of Orthopaedics, The Third Military Medical University, Chongqing, China.
authors: Jianzhong
authors: J
authors: Xu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001843:Bone Cements / Q000627:therapeutic use*; D002484:Cementation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007796:Laminectomy / Q000379:methods; D017116:Low Back Pain / Q000601:surgery; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D058866:Osteoporotic Fractures / Q000601:surgery*; D065289:Pedicle Screws; D019904:Polymethyl Methacrylate / Q000627:therapeutic use*; D016103:Spinal Fractures / Q000601:surgery*; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate