title: Sinecatechins 10% ointment: a green tea extract for the treatment of external genital warts.
abstract: External genital warts (EGWs) resulting from the human papilloma virus (HPV) are a common sexually transmitted infection and cause significant impairments in patient quality of life and sexual well-being. Therapeutic options for EGWs can be provider-assisted, but many patients opt for treatment that can be applied at home. Sinecatechins 10% ointment is a new botanically based patient-administered therapy for EGWs. It is comprised of >85% catechins, green tea polyphenols that have been shown to possess antioxidant, antiproliferative, antiviral, and antitumor properties. Phase III trials of sinecatechins 10% ointment have demonstrated higher efficacy and lower recurrence rates compared to currently available patient-applied treatments. Therefore, sinecatechins 10% ointment presents an alternative self-administered topical treatment for EGWs.
authors: Division of Dermatology, Department of Medicine, University of Toronto, Toronto, ON, Canada; Mediprobe Research Inc., London, ON, Canada.
authors: Aditya K
authors: AK
authors: Gupta
authors: Mediprobe Research Inc., London, ON, Canada.
authors: Deanne
authors: D
authors: Daigle
mesh_terms: D000287:Administration, Topical; D002392:Catechin / Q000008:administration & dosage* / Q000494:pharmacology; D003218:Condylomata Acuminata / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D009824:Ointments; D030361:Papillomavirus Infections / Q000188:drug therapy / Q000821:virology; D010936:Plant Extracts / Q000008:administration & dosage* / Q000494:pharmacology; D059808:Polyphenols / Q000008:administration & dosage / Q000494:pharmacology; D011788:Quality of Life; D012008:Recurrence; D012646:Self Administration; D013662:Tea / Q000737:chemistry
chemical_list: D009824:Ointments; D010936:Plant Extracts; D059808:Polyphenols; D013662:Tea; D002392:Catechin