title: Two paths to fat.
abstract: Excess caloric intake leads to both the growth of existing fat cells and the generation of new adipocytes. New findings show that PI3K-Akt2 signalling is involved in the differentiation of adult adipose precursor cells—a pathway not required for adipogenesis in the embryo.
authors: Division of Endocrinology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
authors: Evan D
authors: ED
authors: Rosen
mesh_terms: D052438:Adipocytes, White / Q000166:cytology*; D050156:Adipogenesis / Q000502:physiology*; D000818:Animals; D008297:Male; D009765:Obesity / Q000378:metabolism*; D019869:Phosphatidylinositol 3-Kinases / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism*
chemical_list: D019869:Phosphatidylinositol 3-Kinases; C494922:Akt2 protein, mouse; D051057:Proto-Oncogene Proteins c-akt