title: Aminobisphosphonate Polymers via RAFT and a Multicomponent Kabachnik-Fields Reaction.
abstract: Polyacrylamides containing pendant aminobisphosphonate groups are synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization and a multicomponent postpolymerization functionalization reaction. A Moedritzer-Irani reaction installs the phosphonic acid groups on well-defined, RAFT-generated polymers bearing a pendant amine. An alternate route to the same materials is developed utilizing a three-component Kabachnik-Fields reaction and subsequent dealkylation. Kinetics of the RAFT polymerization of the polymer precursor are studied. Successful functionalization is demonstrated by NMR and FTIR spectroscopy and elemental analysis of the final polymers.
authors: George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry, University of Florida, Gainesville, Florida, 32611-7200, USA.
authors: Patricia R
authors: PR
authors: Bachler
authors: Michael D
authors: MD
authors: Schulz
authors: Chelsea A
authors: CA
authors: Sparks
authors: Kenneth B
authors: KB
authors: Wagener
authors: Brent S
authors: BS
authors: Sumerlin
mesh_terms: D000588:Amines / Q000737:chemistry*; D004164:Diphosphonates / Q000737:chemistry*; D007700:Kinetics; D011108:Polymers / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000588:Amines; D004164:Diphosphonates; D011108:Polymers
keywords: Kabachnik-Fields; Moedritzer-Irani; aminobisphosphonate; multicomponent reactions; postpolymerization reactions; reversible addition-fragmentation chain transfer