title: A novel polynorbornene-based chemosensor for the fluorescence sensing of Zn2+ and Cd2+ and subsequent detection of pyrophosphate in aqueous solutions.
abstract: A hydroxyquinoline functionlized polynorbornene (P1) was designed and synthesized. In an aqueous solution, P1 shows a "turn-on" fluorescence response for Zn(2+) and Cd(2+) with a 50 nm blue shift. Furthermore, both P1-Zn(2+) and P1-Cd(2+) complexes were found to respond to pyrophosphate (PPi) over other important biological anions via a fluorescence quenching effect. P1 is also capable of monitoring intracellular Zn(2+) and PPi in real time.
authors: Department of Chemistry, Nanchang University, Nanchang 330031, P. R. China. cqyong@ncu.edu.cn.
authors: Pei-Shui
authors: PS
authors: Yao
authors: Zhanghua
authors: Z
authors: Liu
authors: Jin-Zhu
authors: JZ
authors: Ge
authors: Yong
authors: Y
authors: Chen
authors: Qian-Yong
authors: QY
authors: Cao
mesh_terms: D000838:Anions / Q000737:chemistry; D002104:Cadmium / Q000737:chemistry*; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D011756:Diphosphates / Q000032:analysis*; D056945:Hep G2 Cells; D006801:Humans; D008856:Microscopy, Fluorescence; D010969:Plastics / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D014867:Water / Q000737:chemistry; D015032:Zinc / Q000737:chemistry*
chemical_list: D000838:Anions; D056831:Coordination Complexes; D011756:Diphosphates; D010969:Plastics; C071464:polynorbornen; D002104:Cadmium; D014867:Water; C107241:diphosphoric acid; D015032:Zinc