title: Prevalence and trends of isolated systolic hypertension among untreated adults in the United States.
abstract: The prevalence and long-term trends of isolated systolic hypertension (ISH) among untreated adults have not been reported. Data from 24,653 participants aged ≥18 years were selected from the National Health and Nutrition Examination Survey 1999-2010. The prevalence and 95% confidence intervals (CIs) of untreated ISH were estimated by conducting the independent survey t-test. The prevalence of untreated ISH was 9.4% and decreased from 10.3% in 1999-2004 to 8.5% in 2005-2010 (P = .00248). Old persons, females, and non-Hispanic blacks had higher prevalence of untreated ISH. Compared with 1999-2004, the prevalence of untreated ISH in 2005-2010 decreased among older (33.6%; 95% CI, 30.9%-36.3% vs. 25.1%; 95% CI, 22.7%-27.5%) and female individuals (8.3%; 95% CI, 7.5-9.2% vs. 11.4%; 95% CI, 10.4-12.3%). The stratified prevalence of untreated ISH declined in 2005-2010 (vs. 1999-2004) for older non-Hispanic whites (24.6% vs. 32.8%; P < .0001) and blacks (27.7% vs. 40.8%; P = .0013), non-Hispanic white females (7.5% vs. 10.8%; P < .0001), older individuals with higher education (21.0% vs. 30.6%; P = .0024), and females with lower education (10.1% vs. 13.1%; P = .006). Untreated ISH is more prevalent in older adults and females. Significant decreases in untreated ISH prevalence over time among these groups suggest that public health measures and/or treatment patterns are trending in the right direction.
authors: Department of Systems Leadership and Effectiveness Science, University of Michigan, Ann Arbor, MI, USA. Electronic address: liuxf@med.umich.edu.
authors: Xuefeng
authors: X
authors: Liu
authors: Division of Public Health Sciences, Department of Epidemiology, Wake Forest School of Medicine, Winston-Salem, NC, USA; Department of Internal Medicine (Cardiology), Wake Forest School of Medicine, Winston-Salem, NC, USA.
authors: Carlos J
authors: CJ
authors: Rodriguez
authors: Department of Biostatistics and Epidemiology, East Tennessee State University, Johnson City, TN, USA.
authors: Kesheng
authors: K
authors: Wang
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D003710:Demography; D005006:Ethnicity; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D015995:Prevalence; D012737:Sex Factors; D012959:Socioeconomic Factors; D014481:United States / Q000453:epidemiology
keywords: Blood pressure; hypertension; isolated systolic hypertension; prevalence