title: Designed synthesis of MOF-derived magnetic nanoporous carbon materials for selective enrichment of glycans for glycomics analysis.
abstract: In this work, magnetic nanoporous carbon (NPC) materials were synthesized by choosing a MOF as a sacrificial template and a carbon precursor. The obtained Co-ZIF-67 materials showed strong magnetic response, high surface area, a uniform size of mesopores and high carbon content. The Co-ZIF-67 materials were successfully applied to glycomics analysis by enriching N-linked glycans in bio-samples with high selectivity and efficiency.
authors: Department of Chemistry and Institutes of Biomedical Sciences, Fudan University, Shanghai, 200433, China. chdeng@fudan.edu.cn.
authors: Nianrong
authors: N
authors: Sun
authors: Xiangmin
authors: X
authors: Zhang
authors: Chunhui
authors: C
authors: Deng
mesh_terms: D000818:Animals; D002244:Carbon / Q000737:chemistry; D054794:Glycomics; D006801:Humans; D057230:Limit of Detection; D008280:Magnetics; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008422:Materials Testing; D051379:Mice; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D036103:Nanotechnology / Q000379:methods*; D009584:Nitrogen / Q000737:chemistry; D011134:Polysaccharides / Q000737:chemistry*; D016062:Porosity; D012997:Solvents / Q000737:chemistry; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D058185:Magnetite Nanoparticles; D011134:Polysaccharides; D012997:Solvents; D002244:Carbon; D009584:Nitrogen