title: Head and neck skin cancer in the immunocompromised patient: a quantitative analysis.
abstract: BACKGROUND
  Non-melanoma skin cancers (NMSC) are especially prone to develop in the immunosuppressed population. There is insufficient data regarding outcomes and mortality for immunosuppressed individuals with NMSC of the head and neck.
  
  
  OBJECTIVE
  What are the mortality indicators for immunosuppressed subjects with head and neck NMSC?
  
  
  METHODS
  This retrospective chart review analyzes all immunosuppressed patients diagnosed with any stage NMSC at an academic tertiary care institution from 2006-2011.
  
  
  RESULTS
  Thirty four patients are analyzed. Odds of mortality is significantly increased for patients who required multiple surgeries (adjusted odds ratio (aOR)=23.98, 95%CI=(1.411, 407.599)) and those who were immunocompromised secondary to leukemia (aOR=28.27, 95%CI=(1.838, 434.73)).
  
  
  CONCLUSIONS
  Patients with leukemia and NMSC may have an increased risk of mortality compared to other immunocompromised patients with NMSC. Immunocompromised patients with NMSC may have a worse prognosis if multiple surgeries are required. Knowledge of mortality indicators may aid in the management of these immunocompromised patients.
authors: Benjamin
authors: B
authors: Collins
authors: Chelsey
authors: C
authors: Smith
authors: Michael
authors: M
authors: Anderson
authors: Sherief
authors: S
authors: Garrana
authors: Pamela
authors: P
authors: Allen
authors: Nilesh R
authors: NR
authors: Vasan
mesh_terms: D000328:Adult; D000368:Aged; D019985:Benchmarking; D002280:Basal Cell Carcinoma / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery; D006785:Hospitals, University; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D016347:Medical Records Systems, Computerized; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D016019:Survival Analysis