title: Temporal trends in chorioamnionitis by maternal race/ethnicity and gestational age (1995-2010).
abstract: Objective. To characterize trends in chorioamnionitis (CAM) by maternal race/ethnicity and gestational age. Study Design. We examined trends in CAM from 1995-2010 among singleton births in all Kaiser Permanente Southern California hospitals (n = 471,821). Data were extracted from Perinatal Service System and clinical utilization records. Gestational age- and race/ethnicity-specific biannual diagnosis rates were estimated using the Poisson regression after adjusting for potential confounding factors. Results. Overall diagnosis rates of CAM increased from 2.7% in 1995-1996 to 6.0% in 2009-2010 with a relative increase of 126% (95% confidence intervals [CI] 113%-149%). From 1995-1996 to 2009-2010, CAM increased among the Whites (1.8% to 4.3%, P-value for trend <.001), Blacks (2.2% to 3.7%, P-value for trend <.001), Hispanics (2.4% to 5.8%, P-value for trend <.001), and Asian/Pacific Islanders (3.6% to 9.0%, P-value for trend <.001). The adjusted relative percentage change in CAM from 1995-1996 to 2009-2010 was for Whites [preterm 21% (9%-78%), term 138% (108%-173%)], for Blacks [preterm 24% (-9%-81%), term 62% (30%-101%)], for Hispanics [preterm 31% (3%-66%), term 135% (114%-159%)], and for Asian/Pacific Islanders [preterm 44% (9%-127%), term 145% (109%-188%)]. Conclusion. The findings suggest that CAM diagnosis rate has increased for all race/ethnic groups. This increase is primarily due to increased diagnosis at term gestation.
authors: Division of Maternal-Fetal Medicine, Department of Obstetrics-Gynecology, West Los Angeles Kaiser Permanente Southern California Medical Group, Los Angeles, CA 90034, USA.
authors: Michael J
authors: 0000-0002-3369-5916
authors: MJ
authors: Fassett
authors: Division of Maternal-Fetal Medicine, Department of Obstetrics-Gynecology, University of California, Irvine, CA 92868, USA.
authors: Deborah A
authors: DA
authors: Wing
authors: Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA 91101, USA ; Department of Obstetrics and Gynecology, University of Medicine and Dentistry New Jersey, New Brunswick, NJ 08901, USA.
authors: Darios
authors: 0000-0003-3610-8841
authors: D
authors: Getahun