title: Draft genome sequence of Acinetobacter sp. neg1 capable of degrading ochratoxin A.
abstract: Ochratoxin A (OTA) is a nephrotoxic and potentially carcinogenic mycotoxin produced by several species of Aspergillus and Penicillium. It is one of the major mycotoxins contaminating grain, grapes and a variety of food products, and the development of methods for reducing pre- and post-harvest contamination has drawn considerable attention. In the current study, we isolated and sequenced the genome of a novel free-living Acinetobacter strain able to degrade OTA. Biochemical studies suggest that the degradation reaction proceeds via peptide bond hydrolysis.
authors: Institute of Sciences of Food Production, National Research Council, Bari, 70126, Italy.
authors: Francesca
authors: F
authors: Fanelli
authors: Dipartimento di Bioscienze, Università degli Studi di Milano, Milan, 20133, Italy Institute of Biomembranes and Bioenergetics, National Research Council, Bari, 70126, Italy.
authors: Matteo
authors: M
authors: Chiara
authors: Institute of Sciences of Food Production, National Research Council, Bari, 70126, Italy.
authors: Vania C
authors: VC
authors: Liuzzi
authors: Institute of Sciences of Food Production, National Research Council, Bari, 70126, Italy.
authors: Miriam
authors: M
authors: Haidukowski
authors: Institute of Sciences of Food Production, National Research Council, UOS-Lecce, 73100, Italy.
authors: Mariana
authors: M
authors: Tristezza
authors: Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, 70124, Italy.
authors: Manzari
authors: M
authors: Caterina
authors: Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, 70124, Italy.
authors: Anna Maria
authors: AM
authors: D'Erchia
authors: Institute of Biomembranes and Bioenergetics, National Research Council, Bari, 70126, Italy Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari, 70124, Italy Center of Excellence in Comparative Genomics, University of Bari, Bari, 70126, Italy.
authors: Graziano
authors: G
authors: Pesole
authors: Dipartimento di Bioscienze, Università degli Studi di Milano, Milan, 20133, Italy.
authors: David S
authors: DS
authors: Horner
authors: Institute of Sciences of Food Production, National Research Council, Bari, 70126, Italy giuseppina.mule@ispa.cnr.it.
authors: Giuseppina
authors: G
authors: Mule
mesh_terms: D000150:Acinetobacter / Q000235:genetics* / Q000378:metabolism; D001483:Base Sequence; D005516:Food Microbiology; D016680:Genome, Bacterial; D006868:Hydrolysis; D008969:Molecular Sequence Data; D009793:Ochratoxins / Q000378:metabolism*; D010802:Phylogeny; D017422:Sequence Analysis, DNA
chemical_list: D009793:Ochratoxins; C025589:ochratoxin A
keywords: Acinetobacter; degradation; ochratoxin A