title: Clear cell variant of calcifying epithelial odontogenic tumor: Case report with immunohistochemical findings.
abstract: Calcifying epithelial odontogenic tumor (CEOT) is a rare benign odontogenic neoplasm, locally aggressive, characterized by sheets and nests of polyhedral epithelial cells exhibiting eosinophilic cytoplasm or less often clear cytoplasm. Additional features include nuclear pleomorphism without mitotic activity, concentric calcifications, and deposits of amyloid. Herein, we present an additional example of clear cell variant of CEOT occurring in a 25-year-old female. Microscopically, the tumor consisted on proliferation of epithelial cells with eosinophilic, clear vacuolated cytoplasm interspersed with focal areas of amyloid deposition. Tumor cells were immunopositive for AE1/AE3, CK14, CK19, β-catenin, CD138, and p63. Key words:Calcifying epithelial odontogenic tumor, clear cell, histopathology, immunohistochemistry.
authors: DDS, PhD. Department of Oral Pathology, School of Dentistry, University of Fortaleza, UNIFOR.
authors: Eveline
authors: E
authors: Turatti
authors: DDS, MSc. Department of Oral Pathology, School of Dentistry, University of Fortaleza, UNIFOR.
authors: Juviano
authors: J
authors: Brasil
authors: DDS, PhD. Department of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro, UFRJ.
authors: Bruno-Augusto-Benevenuto
authors: BA
authors: de Andrade
authors: DDS, PhD. Department of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro, UFRJ.
authors: Mário-José
authors: MJ
authors: Romañach
authors: DDS, PhD. Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, FOP-UNICAMP.
authors: Oslei-Paes
authors: OP
authors: de Almeida