title: Phenobarbital-responsive sialadenosis in dogs: case series.
abstract: Phenobarbital-responsive sialadenosis (PRS) is a rare idiopathic disease in dogs. Vomiting, retching, and gulping with bilateral enlargement of the submandibular salivary glands are the more frequent clinical signs. A thorough diagnostic examination must be performed to rule out the most important systemic etiologies involved with chronic vomiting, as there is no specific test to diagnose PRS. Diagnosis is confirmed clinically by a rapid and dramatic improvement of clinical signs after instauration of phenobarbital treatment. The aim of this article is to describe the clinical presentation, diagnostic findings, and outcome of a case series of 4 dogs with presumptive PRS.
authors: Hospital Clinic Veterinari Fundation, Autonomous University of Barcelona (UAB), Barcelona, Spain. Electronic address: e.alcoverro.balart@gmail.com.
authors: Emili
authors: E
authors: Alcoverro
authors: Centro Policlínico Veterinario Raspeig, Alicante, Spain.
authors: Maria Dolores
authors: MD
authors: Tabar
authors: Hospital Clinic Veterinari Fundation, Autonomous University of Barcelona (UAB), Barcelona, Spain.
authors: Albert
authors: A
authors: Lloret
authors: Hospital Clinic Veterinari Fundation, Autonomous University of Barcelona (UAB), Barcelona, Spain.
authors: Xavier
authors: X
authors: Roura
authors: Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona (UAB), Barcelona, Spain.
authors: Josep
authors: J
authors: Pastor
authors: Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona (UAB), Barcelona, Spain.
authors: Marta
authors: M
authors: Planellas
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy; D004285:Dogs; D005260:Female; D018757:GABA Modulators / Q000627:therapeutic use*; D008297:Male; D010634:Phenobarbital / Q000627:therapeutic use*; D012793:Sialadenitis / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D018757:GABA Modulators; D010634:Phenobarbital
keywords: phenobarbital; salivary gland; sialadenosis; vomiting