title: An alternative marker of low-density lipoprotein cholesterol in coronary artery disease: non-high-density lipoprotein cholesterol.
abstract: OBJECTIVE
  Dyslipidemia is one of the most important risk factors for coronary artery disease (CAD), and low-densitylipoprotein cholesterol (LDL-C) is used to measure dyslipidemia. Non-high-density lipoprotein cholesterol (non-HDL-C) seems to be an alternative parameter to LDL-C as it is not influenced by triglyceride (TG) levels. The aim of this study is to compare non-HDL-C and LDL-C levels as risk markers in CAD patients.
  
  
  METHODS
  One hundred and ten CAD patients and 42 individuals with normal coronary angiography results were included in this study. Patients were divided into 2 groups: TG < 200 mg/dL (n = 75) as group 1 and TG > 200 mg/dL (n = 35) as group 2. Total cholesterol (TC), TG, and HDL-C levels were analyzed with a Roche Modular P800 autoanalyzer. LDL-C and non-HDL-C levels were calculated.
  
  
  RESULTS
  There were statistically significant differences in TC, TG, HDL-C, and non-HDL-C levels when the groups were compared. Non-HDL-C levels of group 2 were statistically higher than those of group 1 and the control group. There was no significant difference in LDL-C levels between the groups.
  
  
  CONCLUSIONS
  Non-HDL-C levels are better risk markers than LDL-C levels, especially in patients with TG > 200 mg/dL, and non-HDL-C levels should be taken into consideration when evaluating the risk of CAD.
authors: Müjgan
authors: M
authors: Ercan
authors: Esra
authors: E
authors: Oğuz
authors: Fatma Meriç
authors: FM
authors: Yilmaz
authors: Nihal
authors: N
authors: Boğdaycioğlu
authors: Kübranur
authors: K
authors: Ünal
authors: Deniz
authors: D
authors: Şahin
authors: Sema
authors: S
authors: Uysal
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood; D003324:Coronary Artery Disease / Q000097:blood*; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008875:Middle Aged
chemical_list: D015415:Biomarkers; D008078:Cholesterol, LDL; D008074:Lipoproteins; D002784:Cholesterol