title: Health status and quality of life in tuberculosis.
abstract: Tuberculosis (TB) is a leading cause of global morbidity, yet there is limited information regarding its impact on quality of life and health status. This is surprising given the implications for patient care, the evaluation of novel treatments or preventative strategies, and also health policy. Furthermore, there is no validated TB-specific instrument that measures health status, and thus a wide and non-standardized range of assessment tools have been employed. The studies to date have chosen a number of different comparator populations, and in many TB endemic areas there is a lack of normative data regarding the health status of the general population. Systematic evaluations of quality of life are urgently needed in specific groups, including those with extrapulmonary TB, drug-resistant disease, HIV co-infection, and latent TB infection, and in children with TB; the assessment of post-treatment disability is also required.
authors: Centre for Respiratory Medicine, Royal Free London NHS Foundation Trust, London, and Division of Medicine, University College London, Pond Street, London NW3 2QG, UK. Electronic address: james.brown.14@ucl.ac.uk.
authors: James
authors: J
authors: Brown
authors: Centre for Respiratory Medicine, Royal Free London NHS Foundation Trust, London, and Division of Medicine, University College London, Pond Street, London NW3 2QG, UK.
authors: Santino
authors: S
authors: Capocci
authors: Research Department of Infection and Population Health, University College London, London, UK.
authors: Colette
authors: C
authors: Smith
authors: Department of Applied Health Research, University College London, London, UK.
authors: Steve
authors: S
authors: Morris
authors: Research Department of Infection and Population Health, University College London, London, and Medical Research Council Clinical Trials Unit, London, UK.
authors: Ibrahim
authors: I
authors: Abubakar
authors: Centre for Respiratory Medicine, Royal Free London NHS Foundation Trust, London, and Division of Medicine, University College London, Pond Street, London NW3 2QG, UK.
authors: Marc
authors: M
authors: Lipman
mesh_terms: D000328:Adult; D002648:Child; D060085:Coinfection; D005260:Female; D015658:HIV Infections / Q000150:complications; D006304:Health Status; D006801:Humans; D009017:Morbidity; D011788:Quality of Life; D014376:Tuberculosis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy
keywords: Health economics; Health status; Measures of health; Quality of life; Tuberculosis