title: Synthesis, characterization and biological studies of a charge transfer complex: 2-aminopyridinium-4-methylbenzenesulfonate.
abstract: A single crystal charge transfer (CT) complex, 2-aminopyridinium-4-methylbenzenesulfonate (APTS) was synthesized and recrystallized by slow solvent evaporation solution growth method at room temperature. The complex has been characterized with the elemental analysis, UV-visible, infrared (IR), (1)H and (13)C nuclear magnetic resonance (NMR) spectra. Thermogravimetric (TG) and differential thermal analysis (DTA) were reported the thermal behaviour of the complex. Single crystal XRD studies showed that the orthorhombic nature of the crystal with space group Pbca. The biological activities of CT complex, such as DNA binding and antioxidant activity has been carried out. The results indicated that the compound could interact with DNA through intercalation and show significant capacity of scavenging with 2,2-diphenyl-2-picryl-hydrazyl (DPPH).
authors: Department of Chemistry, Hindusthan Institute of Technology, Coimbatore, Tamil Nadu, India.
authors: Ganesan
authors: G
authors: Vadivelan
authors: Post Graduate and Research Department of Chemistry, Sri Ramakrishna Mission Vidyalaya College of Arts and Science, Coimbatore, Tamil Nadu, India.
authors: Munusamy
authors: M
authors: Saravanabhavan
authors: Post Graduate and Research Department of Chemistry, Sri Ramakrishna Mission Vidyalaya College of Arts and Science, Coimbatore, Tamil Nadu, India.
authors: Venkatesan
authors: V
authors: Murugesan
authors: Post Graduate and Research Department of Chemistry, Sri Ramakrishna Mission Vidyalaya College of Arts and Science, Coimbatore, Tamil Nadu, India. Electronic address: mmsekar7@gmail.com.
authors: Marimuthu
authors: M
authors: Sekar
mesh_terms: D000631:Aminopyridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism*; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D001557:Benzenesulfonates / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism*; D066241:Carbon-13 Magnetic Resonance Spectroscopy; D002417:Cattle; D018360:Crystallography, X-Ray; D004247:DNA / Q000378:metabolism; D004583:Electrons; D008968:Molecular Conformation; D066244:Proton Magnetic Resonance Spectroscopy; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: C573194:4-methylbenzenesulfonic acid; D000631:Aminopyridines; D000975:Antioxidants; D001557:Benzenesulfonates; D004247:DNA; C427203:calf thymus DNA; C032439:alpha-aminopyridine
keywords: Antioxidant; Charge transfer; DNA binding; Single crystal; Thermal analysis