title: Central serous chorioretinopathy treatment with spironolactone: a challenge-rechallenge case.
abstract: OBJECTIVE
  To present a case of central serous chorioretinopathy (CSC) treatment with spironolactone in a challenge-rechallenge pattern.
  
  
  METHODS
  At presentation, fundus photography, fluorescein angiography, spectral domain optical coherence tomography, and enhanced depth imaging ocular coherence tomography were performed in both eyes. The patient was prescribed 25 mg spironolactone daily along with serum potassium monitoring. At follow-ups, spectral domain optical coherence tomography and enhanced depth imaging ocular coherence tomography were performed.
  
  
  RESULTS
  A 37-year-old white male accountant presenting with CSC. Spironolactone treatment resolved the CSC. After the patient discontinued treatment, it returned. After returning to daily treatment, the CSC again resolved.
  
  
  CONCLUSIONS
  Spironolactone was an effective treatment of CSC in this case. Other groups have reported similar findings with eplerenone, a similar drug.
authors: VitreoRetinal Surgery, PA, Edina, Minnesota.
authors: Edwin H
authors: EH
authors: Ryan
authors: Christine M
authors: CM
authors: Pulido
mesh_terms: D000328:Adult; D056833:Central Serous Chorioretinopathy / Q000188:drug therapy*; D006801:Humans; D008297:Male; D000451:Mineralocorticoid Receptor Antagonists / Q000627:therapeutic use*; D012008:Recurrence; D019233:Retreatment / Q000379:methods; D012189:Retrospective Studies; D013148:Spironolactone / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000451:Mineralocorticoid Receptor Antagonists; D013148:Spironolactone