title: Contemporary assessment of foot perfusion in patients with critical limb ischemia.
abstract: Significant progress in limb salvage for patients with peripheral arterial disease and critical limb ischemia has occurred in the past 2 decades. Improved patient outcomes have resulted from increased knowledge and understanding of the disease processes, as well as efforts to improve revascularization techniques and enhance patient care after open and endovascular procedures. An imaging modality that is noninvasive, fast, and safe would be a useful tool for clinicians in assessing lower-extremity perfusion when planning interventions. Among the current and emerging regional perfusion imaging modalities are transcutaneous oxygen monitoring, hyperspectral imaging, indocyanine green dye-based fluorescent angiography, nuclear diagnostic imaging, and laser Doppler. These tests endeavor to delineate regional foot perfusion to guide directed revascularization therapy in patients with critical limb ischemia and foot ulceration.
authors: Department of Vascular Surgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510.
authors: Erik
authors: E
authors: Benitez
authors: Department of Vascular Surgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510.
authors: Brandon J
authors: BJ
authors: Sumpio
authors: Department of Vascular Surgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510.
authors: Jason
authors: J
authors: Chin
authors: Department of Vascular Surgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510. Electronic address: bauer.sumpio@yale.edu.
authors: Bauer E
authors: BE
authors: Sumpio
mesh_terms: D000792:Angiography; D001783:Blood Flow Velocity; D001785:Blood Gas Monitoring, Transcutaneous; D016638:Critical Illness; D005528:Foot / Q000098:blood supply*; D006801:Humans; D007511:Ischemia / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D017078:Laser-Doppler Flowmetry; D055420:Perfusion Imaging / Q000379:methods*; D058729:Peripheral Arterial Disease / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis; D012039:Regional Blood Flow; D013057:Spectrum Analysis; D014055:Tomography, Emission-Computed