title: Great toenail dystrophy: a single-center experience and review of the literature.
abstract: BACKGROUND
  There have been a few reported cases of congenital great toenail dystrophy (GTND), described as a congenital malalignment of the great toenails. However, acquired GTDN is rare, and has not been documented extensively. This study aimed to describe the clinical features of 21 patients with acquired GTND.
  
  
  METHODS
  Twenty-one patients with acquired GTND who visited Yeouido St. Mary's Hospital between June 2005 and August 2012 were retrospectively reviewed.
  
  
  RESULTS
  The mean patient age was 43.1 years (range, 17 to 88 years), and the cohort predominantly comprised women (18/21). In our experience, all acquired GTND patients presented with yellow or yellow-brownish chromonychia, onychotrophy, and onycholysis. Conservative treatment with tape methods and grinding, as well as nail extraction, was provided and yielded little improvement in any case.
  
  
  CONCLUSIONS
  This study provides initial data on the nail changes affecting the great toenail, such as yellowish chromonychia, onychomadesis, and onycholysis. These data may help physicians to distinguish various nail disorders, including onychomycosis, congenital malalignment of the great toenails, and yellow nail syndrome.
authors: Department of Dermatology, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors: Miri
authors: M
authors: Kim
authors: Department of Dermatology, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors: Jin Hee
authors: JH
authors: Kang
authors: Department of Dermatology, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors: Baik Kee
authors: BK
authors: Cho
authors: Department of Family Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors: Chan Hee
authors: CH
authors: Song
authors: Department of Family Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors: Sun Myeong
authors: SM
authors: Ock
authors: Department of Dermatology, The Catholic University of Korea College of Medicine, Seoul, Korea.
authors: Hyun Jeong
authors: HJ
authors: Park
keywords: Great Toenail Dystrophy; Onychomadesis; Onychomycosis; Retronychia; Yellow Nail Syndrome