title: Prelude to oral microbes and chronic diseases: past, present and future.
abstract: Associations between oral and systemic health are ancient. Oral opportunistic bacteria, particularly, Porphyromonas gingivalis and Fusobacterium nucleatum, have recently been deviated from their traditional roles as periodontal pathogens and arguably ascended to central players based on their participations in complex co-dependent mechanisms of diverse systemic chronic diseases risk and pathogenesis, including cancers, rheumatoid-arthritis, and diabetes.
authors: Department of Periodontology, University of Florida, Gainesville, FL 32610, USA.
authors: Kalina R
authors: KR
authors: Atanasova
authors: Department of Periodontology, University of Florida, Gainesville, FL 32610, USA; Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA. Electronic address: oyilmaz@ufl.edu.
authors: Özlem
authors: Ö
authors: Yilmaz
mesh_terms: D065567:Absorption, Physiological / Q000276:immunology*; D002908:Chronic Disease; D000069196:Gastrointestinal Microbiome / Q000276:immunology*; D054884:Host-Pathogen Interactions / Q000276:immunology*; D006801:Humans; D008827:Microbiological Phenomena / Q000276:immunology*; D019242:Oral Medicine
keywords: Cancer; Chronic diseases; Fusobacterium nucleatum; Oral microbes; Porphyromonas gingivalis; Small molecule danger signaling