title: Visual acuity improvement in adult amblyopic eyes with an iris-fixated phakic intraocular lens: long-term results.
abstract: OBJECTIVE
  To evaluate the effect of implantation of iris-fixated phakic intraocular lenses (pIOLs) (Artisan) in adult amblyopic eyes.
  
  
  METHODS
  Optical Express, London, United Kingdom.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  The study analyzed data from 5 years of follow-up of amblyopic eyes that were implanted with iris-fixated pIOLs and had a preoperative corrected distance visual acuity (CDVA) of 6/15 or worse. Visual acuity, refraction, endothelial cell count, and complications were assessed.
  
  
  RESULTS
  Data for 103 eyes were analyzed as 2 groups. Group 1 comprised 82 eyes with myopia or myopic astigmatism, and Group 2 contained 21 eyes with hyperopia or hyperopic astigmatism. The mean preoperative sphere in Group 1 was -13.42 diopters (D) ± 5.62 (SD) with a mean cylinder of -2.35 ± 1.75 D. In Group 2, the mean sphere and cylinder were +6.77 ± 1.91 D and -2.63 ± 2.43 D, respectively. The mean CDVA improved from 0.51 ± 0.15 logMAR to 0.34 ± 0.16 logMAR (P<.001) in Group 1 and from 0.54 ± 0.17 logMAR to 0.46 ± 0.14 logMAR in Group 2 (P<.005). The safety index was 1.48 in Group 1 and 1.19 in Group 2. The efficacy index was 1.21 in Group 1 and 1.00 in Group 2. The mean gain in CDVA was statistically significantly greater in Group 1 (0.17 ± 0.14 logMAR) than in Group 2 (0.08 ± 0.11 logMAR). Two or more lines of CDVA were gained by 48.8% of eyes in Group 1 and by 19.0% of eyes in Group 2.
  
  
  CONCLUSIONS
  The iris-fixated pIOL was a safe and effective option for improving visual acuity in adult amblyopic eyes.
  
  
  BACKGROUND
  Dr. Schallhorn is a consultant to Abbott Medical Optics, Inc. No other author has a financial or proprietary interest in any material or method mentioned.
authors: From Optical Express, London, United Kingdom. Electronic address: drjanventer@gmail.com.
authors: Jan A
authors: JA
authors: Venter
authors: From Optical Express, London, United Kingdom.
authors: Martina
authors: M
authors: Pelouskova
authors: From Optical Express, London, United Kingdom.
authors: Steven C
authors: SC
authors: Schallhorn
authors: From Optical Express, London, United Kingdom.
authors: Barrie M
authors: BM
authors: Collins
mesh_terms: D000328:Adult; D000550:Amblyopia / Q000503:physiopathology / Q000601:surgery*; D001251:Astigmatism / Q000503:physiopathology / Q000601:surgery; D002452:Cell Count; D004728:Endothelium, Corneal / Q000166:cytology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006956:Hyperopia / Q000503:physiopathology / Q000601:surgery; D007431:Intraoperative Complications; D007498:Iris / Q000601:surgery*; D019654:Lens Implantation, Intraocular / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery; D054120:Phakic Intraocular Lenses; D011183:Postoperative Complications; D012029:Refraction, Ocular / Q000502:physiology; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology*; D055815:Young Adult