title: Association between coffee consumption and an oxidative stress marker in women.
abstract: BACKGROUND
  Coffee is one of the major dietary modulators of oxidative stress conditions. Whether coffee consumption is associated with oxidative stress markers, such as derivatives of reactive oxygen metabolites (d-ROMs), remains to be investigated in women, despite one recent report describing their significant association in men.
  
  
  METHODS
  A total of 415 women (49 ± 9 years) attending a general clinic were evaluated regarding their self-reported coffee consumption habits and blood d-ROMs levels.
  
  
  RESULTS
  Women who reported ≥ 3 cups/day of coffee consumption displayed a lower d-ROMs level than those who reported consuming 0-2 cups/day (336 ± 67 vs. 358 ± 80 Carr U; p < 0.05). In the multivariate-adjusted analysis, the association between coffee consumption and the d-ROMs level remained to be significant (p < 0.05).
  
  
  CONCLUSIONS
  Daily coffee consumption (i.e., ≥ 3 cups) may be associated with a reduced oxidative stress status, as measured by the d-ROMs level, among women.
authors: Jui-Tung Chen Clinic, 2-13-5 Akasaka, Akasaka-Kaikan B1F, Minato-Ku, 107-0052, Tokyo, Japan, chin-cl@m.jcnnet.ne.jp.
authors: Jui-Tung
authors: JT
authors: Chen
authors: Kazuhiko
authors: K
authors: Kotani
mesh_terms: D015415:Biomarkers / Q000097:blood; D003069:Coffee; D004327:Drinking Behavior; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008875:Middle Aged; D018384:Oxidative Stress; D017382:Reactive Oxygen Species / Q000097:blood*; D016387:Women's Health / Q000706:statistics & numerical data*
chemical_list: D015415:Biomarkers; D003069:Coffee; D017382:Reactive Oxygen Species