title: Group C Streptococcus Causing Rheumatic Heart Disease in a Child.
abstract: BACKGROUND
  Human infection with group C Streptococcus is extremely rare and a select number of cases have been reported to cause acute pharyngitis, acute glomerulonephritis, skin and soft tissue infections, septic arthritis, osteomyelitis, pneumonitis, and bacteremia. In pediatrics, this bacteria is known to cause epidemic food-borne pharyngitis, pneumonia, endocarditis, and meningitis, and has reportedly been isolated in the blood, meninges, sinuses, fingernail, peritonsillar abscess, and thyroglossal duct cyst, among others.
  
  
  METHODS
  Our patient was a 7-year-old previously healthy female who presented with abnormal movements of her upper body and grimaces of her face that progressively worsened over time. Initial laboratory resulted revealed 3+ protein on urinalysis and elevated antistreptolysin-O and anti-DNAse antibody levels, and echocardiogram showed mild-to-moderate mitral regurgitation. We describe a rare case of group C Streptococcus resulting in rheumatic heart disease in a child, with a detailed review of the literature pertaining to the diagnosis and management of this infection. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Early recognition of rheumatic heart disease is crucial in the overall outcome of the condition and therefore knowledge of the symptoms associated with condition is also imperative. Group C Streptococcus is rarely associated with rheumatic heart disease and most children exhibiting acute onset of common symptoms, such as chorea, fever, carditis, and rash (erythema marginatum) will present to the emergency department first. Increased awareness and prompt recognition, as done with this child, will result in proper follow-up and adequate management of this condition in all patients.
authors: Department of Pediatrics, University of Nevada School of Medicine, Las Vegas, Nevada.
authors: Harsha K
authors: HK
authors: Chandnani
authors: Department of Pediatrics, University of Nevada School of Medicine, Las Vegas, Nevada.
authors: Renu
authors: R
authors: Jain
authors: Department of Pediatrics, University of Nevada School of Medicine, Las Vegas, Nevada.
authors: Pisespong
authors: P
authors: Patamasucon
mesh_terms: D002648:Child; D002819:Chorea / Q000382:microbiology; D005260:Female; D006801:Humans; D009205:Myocarditis / Q000382:microbiology; D012214:Rheumatic Heart Disease / Q000382:microbiology*; D013290:Streptococcal Infections / Q000150:complications* / Q000382:microbiology; D013291:Streptococcus
keywords: carditis; group C Streptococcus; pediatrics; rheumatic heart disease