title: [Influence of heavy metal salts on the activity of trypsin-like hydrolases from Drosophila melanogaster].
abstract: The influence of salts of heavy metals on trypsin-like peptide hydrolase of drosophila larvae partly refined by methods of salting-out, gel chromatography and electrophoresis has been researched. It is established that cadmium chloride is characterized by the greatest inhibitory effect, while zinc chloride by the lowest one. Since metal chlorides were used in all cases, it is the differentiated effect of metal ions on manifestations of amidase activity of trypsin-like peptide hydrolase of drosophila larvae, which rather may be considered as proved than the effect of chlorine ions. This, as a whole, agrees with the effect of these ions on proteolytic digestion system at the level of live organisms.
authors: I L
authors: IL
authors: Ryzhko
authors: N V
authors: NV
authors: Motruk
authors: S A
authors: SA
authors: Petrov
mesh_terms: D000818:Animals; D019256:Cadmium Chloride / Q000737:chemistry*; D002712:Chlorides / Q000737:chemistry; D003035:Cobalt / Q000737:chemistry; D003300:Copper / Q000737:chemistry; D029721:Drosophila Proteins / Q000037:antagonists & inhibitors / Q000737:chemistry / Q000302:isolation & purification*; D004331:Drosophila melanogaster / Q000737:chemistry* / Q000201:enzymology; D057075:Enzyme Assays; D007700:Kinetics; D007814:Larva / Q000737:chemistry / Q000201:enzymology; D010447:Peptide Hydrolases / Q000737:chemistry / Q000302:isolation & purification*; D017967:Zinc Compounds / Q000737:chemistry
chemical_list: D002712:Chlorides; D029721:Drosophila Proteins; D017967:Zinc Compounds; D003035:Cobalt; D003300:Copper; C016837:zinc chloride; D010447:Peptide Hydrolases; C018021:cobaltous chloride; D019256:Cadmium Chloride; C029892:cupric chloride