title: Intraoperative injection of (99mm)Tc- nanocolloid for localization of nonpalpable intratesticular tumours in organ-sparing surgery.
abstract: OBJECTIVE
  Radical orchidectomy is the standard treatment for malignant testis tumours. Radical orchidectomy results in androgen deprivation, infertility and impaired psychological well-being, especially in synchronous bilateral tumours, metachronous contralateral tumours or tumour in a solitary testis. According to the European Association of Urology Guidelines, if pre-operative testosterone level is normal and the tumour volume is less than 30% of the testicular volume, organ preserving surgery can be performed. For nonpalpable tumours, organ-sparing surgery needs a precise intraoperative localization with high-frequency ultrasound, especially for nonpalpable tumours.
  
  
  METHODS
  We report two cases of nonpalpable intratesticular tumours successfully localised using (99mm)Tc nanocolloid injected with intraoperative US and detected with a γ-ray detection probe.
  
  
  CONCLUSIONS
  This method is easily reproducible and safe for the patient. This technique could guarantee complete excision of the tumour, especially if the mass is poorly delimited.
authors: Servicio de Urología, Hospital Germans Trias i Pujol, Badalona, Barcelona, España. Electronic address: jmruizdominguez@gmail.com.
authors: J M
authors: JM
authors: Ruiz-Domínguez
authors: Servicio de Urología, Hospital Germans Trias i Pujol, Badalona, Barcelona, España.
authors: L
authors: L
authors: Ibarz-Servio
authors: Servicio de Urología, Hospital Germans Trias i Pujol, Badalona, Barcelona, España.
authors: G
authors: G
authors: García-de Manuel
authors: Servicio de Urología, Hospital Germans Trias i Pujol, Badalona, Barcelona, España.
authors: O
authors: O
authors: Calaf Perisé
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D033162:Incidental Findings; D007267:Injections; D007430:Intraoperative Care / Q000379:methods*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging* / Q000601:surgery; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging* / Q000601:surgery; D009919:Orchiectomy / Q000379:methods*; D009920:Orchitis / Q000150:complications; D059351:Organ Sparing Treatments / Q000379:methods*; D010173:Palpation; D011877:Radionuclide Imaging / Q000295:instrumentation / Q000379:methods; D012507:Sarcoidosis / Q000175:diagnosis / Q000000981:diagnostic imaging*; D018239:Seminoma / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D025321:Surgery, Computer-Assisted / Q000379:methods*; D013668:Technetium Tc 99m Aggregated Albumin / Q000008:administration & dosage*; D013733:Testicular Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging*; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D018615:Ultrasonography, Doppler, Color
chemical_list: D013668:Technetium Tc 99m Aggregated Albumin; C083602:technetium Tc 99m nanocolloid
keywords: Ecografía testicular intraoperatoria; Intraoperative testicular ultrasound; Intratesticular; No palpable; Nonpalpable; Organ-sparing surgery; Orquiectomía parcial; Tecnecio-99 metaestable; Tecnecium-99mm; Tumor; Tumour