title: Cervical Carcinoma in a Renal Transplant Recipient: A Case Report.
abstract: A range of cancer types, at increased rates, is described in renal transplant recipients receiving immunosuppression. Aside from immunodeficiency, heightened medical surveillance for cancer, lifestyle, and other risk factors all play a role. Although the relation between cancer risk and degree of immunodeficiency might not be linear, and might be different for a wide range of cancer subtypes, human papillomavirus-related cancers in long-term transplant recipients may suggest the role of even modest immunosuppression, when present long enough. High-risk human papillomavirus types are recognized as the cause of cancer of the cervix. We report a 49-year-old female renal transplant recipient diagnosed with cervical squamous cell carcinoma, 5 years after the transplant. Based on this patient, we highlight difficulties in surgical approach and the importance of close clinical follow-up including regular gynecologic screening for cervical premalignant and malignant lesions.
authors: From the Department of Obstetrics and Gynecology, Baskent University Faculty of Medicine, Ankara, Turkey.
authors: Hasan Aykut
authors: HA
authors: Tuncer
authors: Mahir
authors: M
authors: Kirnap
authors: Polat
authors: P
authors: Dursun
authors: Ali
authors: A
authors: Ayhan
authors: Gokhan
authors: G
authors: Moray
authors: Mehmet
authors: M
authors: Haberal
mesh_terms: D001918:Brachytherapy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016030:Kidney Transplantation / Q000009:adverse effects*; D008197:Lymph Node Excision; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D012307:Risk Factors; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000601:surgery
chemical_list: D007166:Immunosuppressive Agents