title: Analytical method development for the determination of emerging contaminants in water using supercritical-fluid chromatography coupled with diode-array detection.
abstract: An analytical method using supercritical-fluid chromatography coupled with diode-array detection for the determination of seven emerging contaminants-two pharmaceuticals (carbamazepine and glyburide), three endocrine disruptors (17α-ethinyl estradiol, bisphenol A, and 17β-estradiol), one bactericide (triclosan), and one pesticide (diuron)-was developed and validated. These contaminants were chosen because of their frequency of use and their toxic effects on both humans and the environment. The optimized chromatographic separation on a Viridis BEH 2-EP column achieved baseline resolution for all compounds in less than 10 min. This separation was applied to environmental water samples after sample preparation. The optimized sample treatment involved a preconcentration step by means of solid-phase extraction using C18-OH cartridges. The proposed method was validated, finding recoveries higher than 94 % and limits of detection and limits of quantification in the range of 0.10-1.59 μg L(-1) and 0.31-4.83 μg L(-1), respectively. Method validation established the proposed method to be selective, linear, accurate, and precise. Finally, the method was successfully applied to environmental water samples.
authors: Facultad de Ciencias Químicas, Universidad de Colima, Carretera Colima-Coquimatlán km 9, 28400, Coquimatlán, Colima, Mexico.
authors: Vilma
authors: V
authors: Del Carmen Salvatierra-Stamp
authors: Silvia G
authors: SG
authors: Ceballos-Magaña
authors: Jorge
authors: J
authors: Gonzalez
authors: Valentin
authors: V
authors: Ibarra-Galván
authors: Roberto
authors: R
authors: Muñiz-Valencia
mesh_terms: D025924:Chromatography, Supercritical Fluid / Q000379:methods; D057230:Limit of Detection; D015203:Reproducibility of Results; D014867:Water / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000737:chemistry*
chemical_list: D014874:Water Pollutants, Chemical; D014867:Water