title: Antibacterial behaviour of Vitex negundo extract assisted ZnO nanoparticles against pathogenic bacteria.
abstract: The biological routes are advantageous over the chemical and physical ones as unlike. These, the biological synthesis protocol occurs at ambient conditions, are cheap, non-toxic and eco-friendly. This research describes the synthesis of zinc oxide nanoparticles (ZnO NPs) using Vitex negundo plant extract with zinc nitrate hexahydrate as precursor. Biomolecules present in plant extract can be used to hydrolyze metal ions into metal oxide NPs in a single-step green synthesis. The hydrolyzing agents involved the various water soluble plant metabolites such as flavonoid, alkaloids, flavone, phenolic compounds, terpenoids and co-enzymes. Presence of isoorientin (flavone) in V. negundo plant extract is mainly responsible for the formation of ZnO NPs. The prepared ZnO NPs were calcinated at 450°C and were confirmed by XRD, FT-IR, UV-visible, SEM with EDX and DLS analysis. The biological application of antibacterial activity was done by gram positive and gram negative bacteria.
authors: Advanced Green Organic Chemistry Lab, Department of Industrial Chemistry, School of Chemical Sciences, Alagappa University, Karaikudi 630003, Tamil Nadu, India.
authors: Subramanian
authors: S
authors: Ambika
authors: Advanced Green Organic Chemistry Lab, Department of Industrial Chemistry, School of Chemical Sciences, Alagappa University, Karaikudi 630003, Tamil Nadu, India. Electronic address: drmsgreenchemistrylab@gmail.com.
authors: Mahalingam
authors: M
authors: Sundrarajan
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D055772:Green Chemistry Technology; D047311:Luteolin / Q000378:metabolism; D053768:Metal Nanoparticles / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000378:metabolism; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000187:drug effects; D020950:Vitex / Q000737:chemistry / Q000378:metabolism*; D014961:X-Ray Diffraction; D015034:Zinc Oxide / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; C057912:homoorientin; D047311:Luteolin; D015034:Zinc Oxide