title: Palladium-catalyzed intermolecular oxidative cyclization of N-aryl enamines with isocyanides through double sp(2) C-H bonds cleavage: facile synthesis of 4-aminoquinoline derivatives.
abstract: An efficient method for the synthesis of 4-aminoquinolines via palladium-catalyzed intermolecular oxidative cyclization of N-aryl enamines and isocyanides through double sp(2) C-H bonds cleavage has been developed.
authors: Key Laboratory of Functional Small Organic Molecules, Ministry of Education and College of Chemistry & Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330022, P. R. China. dqpjxnu@gmail.com.
authors: Qiang
authors: Q
authors: Zheng
authors: Puying
authors: P
authors: Luo
authors: Yuqing
authors: Y
authors: Lin
authors: Wenfan
authors: W
authors: Chen
authors: Xiuxiu
authors: X
authors: Liu
authors: Yadong
authors: Y
authors: Zhang
authors: Qiuping
authors: Q
authors: Ding
mesh_terms: D000634:Aminoquinolines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003432:Cross-Linking Reagents / Q000737:chemistry; D003486:Cyanides / Q000737:chemistry*; D003500:Cyclization; D006834:Hydrazines / Q000737:chemistry; D006860:Hydrogen Bonding; D008024:Ligands; D008670:Metals / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013455:Sulfur / Q000737:chemistry; D013696:Temperature
chemical_list: D000634:Aminoquinolines; D003432:Cross-Linking Reagents; D003486:Cyanides; D006834:Hydrazines; D008024:Ligands; D008670:Metals; D012821:Silanes; D012997:Solvents; C029424:hydrazine; D012834:Silver; D010165:Palladium; D013455:Sulfur; D003300:Copper; C001920:4-aminoquinoline; D010100:Oxygen