title: Importance of tyrosine phosphorylation in receptor kinase complexes.
abstract: Tyrosine phosphorylation is an important post-translational modification that is known to regulate receptor kinase (RK)-mediated signaling in animals. Plant RKs are annotated as serine/threonine kinases, but recent work has revealed that tyrosine phosphorylation is also crucial for the activation of RK-mediated signaling in plants. These initial observations have paved the way for subsequent detailed studies on the mechanism of activation of plant RKs and the biological relevance of tyrosine phosphorylation for plant growth and immunity. In this Opinion article we review recent reports on the contribution of RK tyrosine phosphorylation in plant growth and immunity; we propose that tyrosine phosphorylation plays a major regulatory role in the initiation and transduction of RK-mediated signaling in plants.
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK. Electronic address: alberto.macho@sibs.ac.cn.
authors: Alberto P
authors: AP
authors: Macho
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
authors: Rosa
authors: R
authors: Lozano-Durán
authors: The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK. Electronic address: cyril.zipfel@tsl.ac.uk.
authors: Cyril
authors: C
authors: Zipfel
mesh_terms: D010766:Phosphorylation; D010940:Plant Proteins / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D015398:Signal Transduction; D014443:Tyrosine / Q000378:metabolism*
chemical_list: D010940:Plant Proteins; D014443:Tyrosine; D011494:Protein Kinases
keywords: PAMPs; brassinosteroids; immunity; receptor kinases; tyrosine phosphorylation