title: New septanoside and 20-hydroxyecdysone septanoside derivative from Atriplex portulacoides roots with preliminary biological activities.
abstract: The phytochemical investigation of a Tunisian plant Atriplex portulacoides (Chenopodiaceae) led to the isolation of two new compounds designated as portulasoid (2) and septanoecdysone (3) along with the known 20-hydroxyecdysone (20HE) (1). Their chemical structures were elucidated on the basis of extensive spectroscopic methods including ES-HRMS, 1D and 2D-NMR. The isolated compounds were finally tested for their antioxidant activity by using DPPH, ABTS(+), Fe(3+) and catalase assays and also for their antibacterial and anticholinesterase activities.
authors: Laboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11SE39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Avenue of Environment, 5019 Monastir, Tunisia.
authors: Aymen
authors: A
authors: Ben Nejma
authors: Laboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11SE39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Avenue of Environment, 5019 Monastir, Tunisia.
authors: Asma
authors: A
authors: Nguir
authors: Laboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11SE39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Avenue of Environment, 5019 Monastir, Tunisia. Electronic address: hich.benjannet@yahoo.fr.
authors: Hichem
authors: H
authors: Ben Jannet
authors: Laboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11SE39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Avenue of Environment, 5019 Monastir, Tunisia.
authors: M'hamed Ali
authors: MA
authors: Hamza
authors: URCOM, EA 3221, INC3M CNRS FR-3038, UFR des Sciences et Techniques de l'Université du Havre, 25 Rue Philippe Lebon, B.P. 540, F-76058 Le Havre Cedex, France.
authors: Adam
authors: A
authors: Daïch
authors: URCOM, EA 3221, INC3M CNRS FR-3038, UFR des Sciences et Techniques de l'Université du Havre, 25 Rue Philippe Lebon, B.P. 540, F-76058 Le Havre Cedex, France.
authors: Mohamed
authors: M
authors: Othman
authors: URCOM, EA 3221, INC3M CNRS FR-3038, UFR des Sciences et Techniques de l'Université du Havre, 25 Rue Philippe Lebon, B.P. 540, F-76058 Le Havre Cedex, France. Electronic address: lawsona@univ-lehavre.fr.
authors: Ata Martin
authors: AM
authors: Lawson
mesh_terms: D000975:Antioxidants / Q000737:chemistry; D027466:Atriplex / Q000737:chemistry* / Q000378:metabolism; D002802:Cholinesterases / Q000737:chemistry / Q000378:metabolism; D004441:Ecdysterone / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010936:Plant Extracts / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; C000603604:septanoecdysone; D004441:Ecdysterone; D002802:Cholinesterases
keywords: 20-Hydroxyecdysone; Atriplex portulacoides; Biological activities; Chenopodiaceae; NMR; Portulasoid; Septanoecdysone