title: 2,14-Dithiacalix[4]arene and its homooxa analogues: synthesis and dynamic NMR study of conformational behaviour.
abstract: A simple and scalable synthesis of 2,14-dithiacalix[4]arene with alternating bridges (-CH2- and -S-) is reported. Proper selection of the bisphenol-based starting building blocks can provide not only the title compound (58%) but also yet unreported homooxa analogues possessing three different bridging units (-CH2-, -S- and -CH2-O-CH2-) in the molecule. These systems exhibit interesting conformational behaviour allowing for the study of flip-flop motion of the circular hydrogen bond arrays using dynamic NMR techniques.
authors: Department of Organic Chemistry, Institute of Chemical Technology Prague (ICTP), Technicka 5, 166 28, Prague 6, Czech Republic. lhotakp@vscht.cz.
authors: Michal
authors: M
authors: Hucko
authors: Hana
authors: H
authors: Dvoráková
authors: Václav
authors: V
authors: Eigner
authors: Pavel
authors: P
authors: Lhoták