title: Detection of Autoantibodies Against Myelin Oligodendrocyte Glycoprotein in Multiple Sclerosis and Related Diseases.
abstract: Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) occur in a proportion of patients with different inflammatory demyelinating diseases of the central nervous system, such as childhood multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), and neuromyelitis optica spectrum disorders (NMOSD). We describe here in detail a sensitive cell-based assay that allows the identification of autoantibodies against MOG in serum.
authors: Institute of Clinical Neuroimmunology, Medical Campus Grosshadern, Ludwig Maximilian University, Marchioninistr. 15, 81377, Munich, Germany.
authors: Melania
authors: M
authors: Spadaro
authors: Edgar
authors: E
authors: Meinl
mesh_terms: D001323:Autoantibodies / Q000097:blood / Q000276:immunology*; D004673:Encephalomyelitis, Acute Disseminated / Q000097:blood / Q000276:immunology; D006801:Humans; D009103:Multiple Sclerosis / Q000097:blood / Q000276:immunology*; D063308:Myelin-Oligodendrocyte Glycoprotein / Q000276:immunology*; D009471:Neuromyelitis Optica / Q000097:blood / Q000276:immunology
chemical_list: D001323:Autoantibodies; D063308:Myelin-Oligodendrocyte Glycoprotein