title: Neural control of energy balance: translating circuits to therapies.
abstract: Recent insights into the neural circuits controlling energy balance and glucose homeostasis have rekindled the hope for development of novel treatments for obesity and diabetes. However, many therapies contribute relatively modest beneficial gains with accompanying side effects, and the mechanisms of action for other interventions remain undefined. This Review summarizes current knowledge linking the neural circuits regulating energy and glucose balance with current and potential pharmacotherapeutic and surgical interventions for the treatment of obesity and diabetes.
authors: Division of Hypothalamic Research, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9077, USA. Electronic address: laurent.gautron@utsouthwestern.edu.
authors: Laurent
authors: L
authors: Gautron
authors: Division of Hypothalamic Research, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9077, USA; Department of Pharmacology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9077, USA.
authors: Joel K
authors: JK
authors: Elmquist
authors: Division of Hypothalamic Research, Department of Internal Medicine, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9077, USA; Department of Neuroscience, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9077, USA. Electronic address: kevin.williams@utsouthwestern.edu.
authors: Kevin W
authors: KW
authors: Williams
mesh_terms: D000818:Animals; D001067:Appetite Depressants / Q000627:therapeutic use; D001921:Brain / Q000503:physiopathology; D048909:Diabetes Complications / Q000188:drug therapy / Q000378:metabolism; D004734:Energy Metabolism / Q000187:drug effects; D006801:Humans; D009434:Neural Pathways / Q000187:drug effects; D009765:Obesity / Q000188:drug therapy / Q000378:metabolism
chemical_list: D001067:Appetite Depressants