title: [Level of pepsinogen in patients with gastroesophageal reflux disease].
abstract: We studied level of pepsinogen I and II in blood serum in 50 patients with erosive form of gastroesophageal reflux disease. Increasing concentrations of pepsinogen in 2.1 times and increasing the ratio of pepsinogen I to pepsinogen II in 32% of patients was detected. Which was associated with a higher degree gradation of erosive lesions of the esophagus and acid reflux prevalence with 2.0-2.99 pH range. Higher concentrations of pepsinogen II in serum was diagnosed in 20% of patients, and the results of daily pH monitoring in lower part of esophagus have been registered in them as acidic and alkaline refluxes.
authors: V H
authors: VH
authors: Mishchuk
authors: V B
authors: VB
authors: Boĭchuk
mesh_terms: D050782:Esophageal pH Monitoring; D005260:Female; D005764:Gastroesophageal Reflux / Q000097:blood* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D020116:Pepsinogen A / Q000097:blood*; D020115:Pepsinogen C / Q000097:blood*
chemical_list: D020115:Pepsinogen C; D020116:Pepsinogen A