title: Nerve Fiber Layer Infarcts in Thiamine Deficiency.
abstract: Thiamine deficiency classically manifests as the triad of Wernicke encephalopathy: acute confusional state, ataxic gait, and ocular motor dysfunction. However, most patients do no present with this classic triad. Optic neuropathy in thiamine deficiency is a rare manifestation and is usually associated with fundus appearances of optic disc swelling or optic disc pallor. We present 2 unique cases of thiamine deficiency where the fundus demonstrated peripapillary retinal nerve fiber layer thickening without florid disc swelling or pallor.
authors: Department of Ophthalmology & Visual Sciences, South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, Australia.
authors: Paul I
authors: PI
authors: Sia
authors: David I T
authors: DI
authors: Sia
authors: John L
authors: JL
authors: Crompton
authors: Robert J
authors: RJ
authors: Casson
mesh_terms: D000437:Alcoholism / Q000150:complications; D005260:Female; D006801:Humans; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D009901:Optic Nerve Diseases / Q000209:etiology* / Q000473:pathology*; D012160:Retina / Q000473:pathology*; D013832:Thiamine Deficiency / Q000150:complications* / Q000209:etiology; D041623:Tomography, Optical Coherence; D055815:Young Adult