title: Effect of the interplay between trauma severity and trait neuroticism on posttraumatic stress disorder symptoms among adolescents exposed to a pipeline explosion.
abstract: BACKGROUND
  While numerous studies have explored relevant factors of posttraumatic stress disorder (PTSD) symptoms, there have been few joint investigations of trauma severity and trait neuroticism on the development of PTSD symptoms. This study aims to assess the involvement and interrelationship of trauma severity and neuroticism in the expression of PTSD symptoms among adolescents exposed to an accidental explosion.
  
  
  METHODS
  Six hundred and sixty-two adolescents were recruited from a junior middle school closest to the 2013 pipeline explosion site in China and were assessed using the Explosion Exposure Questionnaire, the NEO Five Factor Inventory-Neuroticism Subscale (FFI-N), and the PTSD Checklist-Civilian (PCL-C). A battery of hierarchical multiple regression analyses and two-way ANOVAs were performed to examine the effect of trauma severity and trait neuroticism on adolescent PTSD symptoms.
  
  
  RESULTS
  Eighty-seven adolescents (13.1%) showed PTSD symptoms after the pipeline explosion. Correlation analysis showed that all the factors of explosion exposure and trait neuroticism were positively associated with adolescent PTSD symptoms. Being male and younger was linked to lower risk for PTSD symptoms. The regression models identified explosion exposure and neuroticism as independent risk factors for PTSD symptoms, and the interactions between trait neuroticism and trauma exposure (personal casualty, degree of influence, total traumatic severity) were related to PTSD symptoms.
  
  
  CONCLUSIONS
  The results highlight the role of trauma exposure and trait neuroticism as risk factors for PTSD symptoms. Therefore, the combination of these two factors should be investigated in clinical settings due to an augmented risk for more severe PTSD symptoms.
authors: School of Nursing, Shandong University, Jinan, Shandong Province, People's Republic of China.
authors: Wei
authors: W
authors: Guo
authors: School of Nursing, Shandong University, Jinan, Shandong Province, People's Republic of China.
authors: Jiao-Mei
authors: JM
authors: Xue
authors: School of Nursing, Shandong University, Jinan, Shandong Province, People's Republic of China.
authors: Di
authors: D
authors: Shao
authors: School of Nursing, Shandong University, Jinan, Shandong Province, People's Republic of China.
authors: Zhou-Ting
authors: ZT
authors: Long
authors: School of Nursing, Shandong University, Jinan, Shandong Province, People's Republic of China.
authors: Feng-Lin
authors: FL
authors: Cao
mesh_terms: D000059:Accidents; D000293:Adolescent; D001008:Anxiety Disorders / Q000150:complications / Q000453:epidemiology*; D005107:Explosions; D006801:Humans; D008297:Male; D000075384:Neuroticism; D012307:Risk Factors; D013313:Stress Disorders, Post-Traumatic / Q000453:epidemiology* / Q000209:etiology