title: Glycine at the gate--from model to mechanism.
abstract: In this issue of Neuron, Foster et al. (2015) show that ablating, silencing, or activating spinal glycinergic inhibitory neurons with viral vectors all have dramatic effects on pain and itch. These results provide molecular insights into pain gate control and useful tools for the rapid analysis of other CNS circuits.
authors: Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London WC1E 6BT, UK.
authors: Jing
authors: J
authors: Zhao
authors: Molecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London WC1E 6BT, UK. Electronic address: j.wood@ucl.ac.uk.
authors: John N
authors: JN
authors: Wood
mesh_terms: D000818:Animals; D009415:Nerve Net / Q000503:physiopathology*; D009474:Neurons / Q000166:cytology*; D010146:Pain / Q000503:physiopathology*; D066148:Spinal Cord Dorsal Horn / Q000166:cytology*