title: Evaluation of functional, autonomic and inflammatory outcomes in children with asthma.
abstract: Asthma is common in childhood. This respiratory disease is characterized by persistent inflammation of the airways even when the child is not in the throes of an attack. Chronic inflammation is caused by an imbalance between pro-inflammatory and anti-inflammatory mechanisms as well as autonomic dysfunction, which plays an important role in the pathogenesis and control of this condition. The impact of these physiopathological aspects leads to inactivity and a sedentary lifestyle, which exerts an influence on functional capacity and control of the disease. The main objective of non-pharmacological therapy is the clinical control of asthma and the minimization of airway obstruction and hyperinflation during an attack. These factors can be controlled with noninvasive ventilation. The aim or the present review was to describe important neural, inflammatory and functional mechanisms that affect children with asthma.
authors: Evelim Leal de Freitas Dantas Gomes, Rehabilitation Sciences, Physical Therapy Course, University Nove de Julho, São Paulo 01504-001, Brazil.
authors: Evelim Leal
authors: EL
authors: de Freitas Dantas Gomes
authors: Evelim Leal de Freitas Dantas Gomes, Rehabilitation Sciences, Physical Therapy Course, University Nove de Julho, São Paulo 01504-001, Brazil.
authors: Dirceu
authors: D
authors: Costa
keywords: Asthma; Autonomic nervous system; Child; Continuous positive airway pressure; Evaluation; Functional capacity; Inflammatory mechanisms; Noninvasive ventilation