title: Entanglement of sepsis, chronic kidney disease, and other comorbidities in patients who develop acute kidney injury.
abstract: Acute kidney injury (AKI) is a common and severe complication for patients in the intensive care setting, often occurring in the setting of sepsis. Both sepsis and AKI are complex and heterogeneous syndromes with overlapping risk factors. Comorbidities - such as chronic kidney disease, diabetes mellitus, liver disease, cardiac disease and cancer - may contribute to the development of these syndromes and complicate their management. Recognition of the complex interplay between comorbid conditions, sepsis, and AKI is key to the successful management of these syndromes.
authors: Division of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI. Electronic address: mheung@umich.edu.
authors: Michael
authors: M
authors: Heung
authors: Section of Nephrology, Department of Medicine, University of Chicago, Chicago, IL.
authors: Jay L
authors: JL
authors: Koyner
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology* / Q000209:etiology; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000453:epidemiology; D006331:Heart Diseases / Q000453:epidemiology; D006801:Humans; D008107:Liver Diseases / Q000453:epidemiology; D009369:Neoplasms / Q000453:epidemiology; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D012121:Respiration, Artificial / Q000706:statistics & numerical data; D012307:Risk Factors; D018805:Sepsis / Q000150:complications / Q000453:epidemiology*; D055397:Ventilator-Induced Lung Injury / Q000453:epidemiology
keywords: Acute kidney injury; critical care; risk factors; sepsis