title: [Safe treatment of lung squamous cell carcinoma with nanoparticle albumin-bound Paclitaxel in a patient with a previous hypersensitivity reaction after docetaxel administration].
abstract: A 61-year-old man was diagnosed with lung squamous cell carcinoma in the lower lobe of the right lung. He had received first-line chemotherapy consisting of cisplatin and docetaxel (DTX); however, an allergic/hypersensitivity reaction occurred shortly after administration of the second course of DTX. Thirty-nine months later, he received nanoparticle albumin-bound paclitaxel (nab-PTX) as sixth-line chemotherapy, which did not produce a hypersensitivity reaction. Hypersensitivity after DTX administration may have been due to the DTX vehicle. Therefore, nab-PTX administered under close supervision is a valid therapeutic option in similar cases.
authors: Dept. of Thoracic Oncology, National Hospital Organization Toneyama National Hospital.
authors: Takeshi
authors: T
authors: Uenami
authors: Masahide
authors: M
authors: Mori
authors: Fumitaka
authors: F
authors: Ageshio
authors: Hiroyuki
authors: H
authors: Kagawa
authors: Hideki
authors: H
authors: Matsui
authors: Akitoshi
authors: A
authors: Satomi
authors: Manabu
authors: M
authors: Niinaka
authors: Hiromi
authors: H
authors: Kimura
authors: Yukihiro
authors: Y
authors: Yano
authors: Tsutomu
authors: T
authors: Yoneda
authors: Toshihiko
authors: T
authors: Yamaguchi
authors: Soichiro
authors: S
authors: Yokota
mesh_terms: D000418:Albumins / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy*; D000077143:Docetaxel; D004342:Drug Hypersensitivity; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000627:therapeutic use*; D043823:Taxoids / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: C520255:130-nm albumin-bound paclitaxel; D000418:Albumins; D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D000077143:Docetaxel; D017239:Paclitaxel