title: Rivaroxaban therapy resulting in the resolution of right atrial thrombosis resistant to ordinary control with warfarin in a patient with atrial fibrillation.
abstract: A 72-year-old man with non-valvular atrial fibrillation and metastatic liver and lung cancer after surgery for colon cancer developed thrombosis in the right atrium one month after decreasing the dose of warfarin due to the introduction of double anti-platelet therapy for coronary stent implantation. Restoring the warfarin dose with ordinary control for two months did not result in any changes in the size of the thrombus; however, the subsequent substitution of rivaroxaban (oral treatment with a direct Factor Xa inhibitor) for warfarin ultimately resolved the thrombosis.
authors: Department of Cardiovascular Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan.
authors: Hiroaki
authors: H
authors: Kawano
authors: Yusuke
authors: Y
authors: Kohno
authors: Seiya
authors: S
authors: Izumida
authors: Akira
authors: A
authors: Tsuneto
authors: Satoki
authors: S
authors: Fukae
authors: Masayoshi
authors: M
authors: Takeno
authors: Yuji
authors: Y
authors: Koide
authors: Koji
authors: K
authors: Maemura
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D003328:Coronary Thrombosis / Q000139:chemically induced / Q000188:drug therapy* / Q000473:pathology; D065427:Factor Xa Inhibitors / Q000008:administration & dosage*; D006325:Heart Atria / Q000187:drug effects* / Q000473:pathology; D006801:Humans; D008297:Male; D009025:Morpholines / Q000008:administration & dosage*; D000069552:Rivaroxaban; D013876:Thiophenes / Q000008:administration & dosage*; D016896:Treatment Outcome; D014812:Vitamin K / Q000037:antagonists & inhibitors; D014859:Warfarin / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D000925:Anticoagulants; D065427:Factor Xa Inhibitors; D009025:Morpholines; D013876:Thiophenes; D014812:Vitamin K; D014859:Warfarin; D000069552:Rivaroxaban