title: Three-dimensional analysis of implanted magnetic-resonance-visible meshes.
abstract: OBJECTIVE
  Our primary objective was to develop relevant algorithms for quantification of mesh position and 3D shape in magnetic resonance (MR) images.
  
  
  METHODS
  In this proof-of-principle study, one patient with severe anterior vaginal wall prolapse was implanted with an MR-visible mesh. High-resolution MR images of the pelvis were acquired 6 weeks and 8 months postsurgery. 3D models were created using semiautomatic segmentation techniques. Conformational changes were recorded quantitatively using part-comparison analysis. An ellipticity measure is proposed to record longitudinal conformational changes in the mesh arms. The surface that is the effective reinforcement provided by the mesh is calculated using a novel methodology. The area of this surface is the effective support area (ESA).
  
  
  RESULTS
  MR-visible mesh was clearly outlined in the images, which allowed us to longitudinally quantify mesh configuration between 6 weeks and 8 months after implantation. No significant changes were found in mesh position, effective support area, conformation of the mesh's main body, and arm length during the period of observation. Ellipticity profiles show longitudinal conformational changes in posterior arms.
  
  
  CONCLUSIONS
  This paper proposes novel methodologies for a systematic 3D assessment of the position and morphology of MR-visible meshes. A novel semiautomatic tool was developed to calculate the effective area of support provided by the mesh, a potentially clinically important parameter.
authors: Department of Development and Regeneration, Cluster Organ Systems, Faculty of Medicine, KU, Leuven, Leuven, Belgium.|Interdepartmental Center for Surgical Technologies, Faculty of Medicine, KU Leuven, Leuven, Belgium.
authors: Nikhil
authors: N
authors: Sindhwani
authors: Department of Development and Regeneration, Cluster Organ Systems, Faculty of Medicine, KU, Leuven, Leuven, Belgium.|Interdepartmental Center for Surgical Technologies, Faculty of Medicine, KU Leuven, Leuven, Belgium.
authors: Andrew
authors: A
authors: Feola
authors: Department of Radiology, University Hospitals Leuven, Leuven, Belgium.
authors: Frederik
authors: F
authors: De Keyzer
authors: Department of Radiology, University Hospitals Leuven, Leuven, Belgium.
authors: Filip
authors: F
authors: Claus
authors: Department of Development and Regeneration, Cluster Organ Systems, Faculty of Medicine, KU, Leuven, Leuven, Belgium.|Interdepartmental Center for Surgical Technologies, Faculty of Medicine, KU Leuven, Leuven, Belgium.
authors: Geertje
authors: G
authors: Callewaert
authors: Department of Development and Regeneration, Cluster Organ Systems, Faculty of Medicine, KU, Leuven, Leuven, Belgium.|Interdepartmental Center for Surgical Technologies, Faculty of Medicine, KU Leuven, Leuven, Belgium.
authors: Iva
authors: I
authors: Urbankova
authors: Centre for Medical Image Computing (CMIC), University College London, London, UK.
authors: Sebastien
authors: S
authors: Ourselin
authors: Laboratory on Cardiovascular Imaging and Dynamics, Department of Cardiovascular Sciences, Faculty of Medicine, KU Leuven, Leuven, Belgium.
authors: Jan
authors: J
authors: D'hooge
authors: Department of Development and Regeneration, Cluster Organ Systems, Faculty of Medicine, KU, Leuven, Leuven, Belgium. Jan.Deprest@uzleuven.be.|Pelvic Floor Unit, University Hospitals Leuven, Leuven, Belgium. Jan.Deprest@uzleuven.be.|Department of Obstetrics and Gynaecology, University Hospitals, KU Leuven, Leuven, 3000, Belgium. Jan.Deprest@uzleuven.be.
authors: Jan
authors: J
authors: Deprest
mesh_terms: D000465:Algorithms; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging; D013526:Surgical Mesh; D057188:Workflow
keywords: Conformational measurements; Contraction; Graft-related complication; Magnetic Resonance; Mesh; Prolapse; Semiautomatic analysis