title: Lethal 5-fluorouracil toxicity in a colorectal patient with severe dihydropyrimidine dehydrogenase (DPD) deficiency.
authors: Department of Pharmacy, Centre Hospitalier Universitaire de Grenoble, Grenoble, France. caroledhelens@yahoo.fr.|CHU Grenoble, Pôle Pharmacie, Pharmacie clinique, Pavillon Vercors, CS 10217, 38043, Grenoble cedex 9, France. caroledhelens@yahoo.fr.
authors: Carole
authors: C
authors: Dhelens
authors: Department of Medical Intensive Care Unit, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.
authors: Agnès
authors: A
authors: Bonadona
authors: Department of Pharmacology, IUCT-O, Institut Claudius Regaud, Toulouse, France.|University Toulouse III Paul Sabatier/EA4553, Toulouse, France.
authors: Fabienne
authors: F
authors: Thomas
authors: Department of Pharmacy, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.
authors: Claire
authors: C
authors: Chapuis
authors: Department of Medical Intensive Care Unit, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.
authors: Leila
authors: L
authors: Potton
authors: Department of Pharmacology, IUCT-O, Institut Claudius Regaud, Toulouse, France.|University Toulouse III Paul Sabatier/EA4553, Toulouse, France.
authors: Sabrina
authors: S
authors: Marsili
authors: Department of Pharmacy, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.|Grenoble-Alpes University UJF-Grenoble 1/CNRS/TIMC-IMAG, UMR 5525/Themas, Grenoble, France.
authors: Pierrick
authors: P
authors: Bedouch
authors: Department of Medical Intensive Care Unit, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.|Grenoble-Alpes University UJF Grenoble 1/Inserm U1039, Grenoble, France.
authors: Carole
authors: C
authors: Schwebel
mesh_terms: D015179:Colorectal Neoplasms / Q000188:drug therapy*; D054067:Dihydropyrimidine Dehydrogenase Deficiency / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged
chemical_list: D005472:Fluorouracil