title: Choice of Peripheral Venoarterial Extra-Corporeal Membrane Oxygenation Cannulation Site in Patients Above 15 kilograms.
abstract: BACKGROUND
  Extracorporeal membrane oxygenation (ECMO) is a life-saving measure for pediatric patients with cardiopulmonary failure. The option of cannulating neck vessels versus those of the groin exists for patients over 15 kg; however, each carries the risk for complications. We present a single-center experience comparing the risks and benefits of these alternate peripheral ECMO cannulation sites.
  
  
  METHODS
  All pediatric patients supported by venoarterial (VA) ECMO via peripheral cannulation from January 2006 to May 2013 were retrospectively reviewed, excluding those weighing less than 15 kg. We compared complications of neck versus groin cannulation sites, including neurologic dysfunction, limb ischemia, and in-hospital mortality. Univariate analysis and multivariable logistic regression were performed to identify factors for complications including mortality.
  
  
  RESULTS
  Thirty-six patients (median age 10.8 years, interquartile range: 6.0-15.8) were cannulated for VA ECMO. Forty-four percent were cannulated via neck vessels and 47% were cannulated via groin. Nine percent were cannulated at both sites. Overall survival was 72% at decannulation and 67% at hospital discharge. No statistically significant survival difference between groin and neck cannulation subgroups was found. Rate of neurologic injury was higher in neck (25%) versus groin (12%) cannulation, but this was not statistically significant (p = 0.52). Extremity ischemia occurred in five patients having groin cannulation (29%, p = 0.04).
  
  
  CONCLUSIONS
  Neck cannulation is a valuable alternative to groin vessels in patients above 15 kg. Risk of limb ischemia with groin cannulation is significant, and must be considered when choosing the cannulation site for ECMO support.
authors: Division of Cardiovascular Surgery, Children's National Health System, Washington DC, USA.
authors: Mustafa
authors: M
authors: Kurkluoglu
authors: Conor F
authors: CF
authors: Hynes
authors: Fahad A
authors: FA
authors: Alfares
authors: Magdy M
authors: MM
authors: El-Sayed Ahmed
authors: Syed M
authors: SM
authors: Peer
authors: David
authors: D
authors: Zurakowski
authors: Richard A
authors: RA
authors: Jonas
authors: Dilip S
authors: DS
authors: Nath
mesh_terms: D000293:Adolescent; D001835:Body Weight; D002406:Catheterization, Peripheral / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D002648:Child; D002675:Child, Preschool; D015199:Extracorporeal Membrane Oxygenation / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D005260:Female; D006119:Groin / Q000098:blood supply; D017052:Hospital Mortality; D006801:Humans; D016015:Logistic Models; D008297:Male; D009333:Neck / Q000098:blood supply; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies; D018570:Risk Assessment