title: Comparison of clinical characteristics of tuberculosis between two age groups at an Italian Tertiary Hospital.
abstract: Differences in clinical characteristics and outcome between elderly (>60 years) and younger (18-59 years) tuberculosis (TB) patients were retrospectively evaluated. Alcohol abuse, radiological evidence of cavitation, and cough at presentation were more frequent among younger patients. Older patients were more likely to have comorbidities, disseminated TB, longer duration of symptoms and higher TB-related mortality (19 vs 0%). Very old patients (≥80 years) showed increased liver toxicity and hospital acquired infections compared to patients aged 60-79 years.
authors: Infectious Diseases Division, Santa Maria della Misericordia University Hospital, 50, Colugna Street, 33100, Udine, UD, Italy, elda.righi@libero.it.
authors: Elda
authors: E
authors: Righi
authors: Paola
authors: P
authors: Della Siega
authors: Maria
authors: M
authors: Merelli
authors: Nadia
authors: N
authors: Castaldo
authors: Anna
authors: A
authors: Beltrame
authors: Federico
authors: F
authors: Pea
authors: Chiara
authors: C
authors: Temperoni
authors: Claudio
authors: C
authors: Scarparo
authors: Matteo
authors: M
authors: Bassetti
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000995:Antitubercular Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016019:Survival Analysis; D062606:Tertiary Care Centers; D016896:Treatment Outcome; D014376:Tuberculosis / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology*; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents