title: [Diastolic dysfunction in hypertrophic nonobstructive cardiomyopathy].
abstract: OBJECTIVE
  The purpose of research was to assess the availability and prevalence of types of diastolic dysfunction of the left ventricle (LV) in hypertrophic nonobstructive cardiomyopathy (NHCM).
  
  
  METHODS
  97 NHCM patients. Mean age 42.5 ± 14.9 years. Diastolic dysfunction assessed by Doppler echocardiography.
  
  
  RESULTS
  Signs of chronic heart failure NYHA class I observed in 44 (45%) patients, class II--in 40 (41%), class II--in 13 (13%) patients. 83% patients had LVdiastolic dysfunction, mainly on the hypertrophic type. One third of the patients had pseudonormal type with uncertain interpretation. Diastolic dysfunction in terms of clinical manifestations determined mainly NYHA class III and syncope. Severity of LV diastolic dysfunction in NHCM depended on the severity of hypertrophy not only left, but the right ventricle too. In 94% of cases we observed not only diastolic dysfunction, but also reduction ofsecondary fibers shortening fraction--as sign of contractile dysfunction.
  
  
  CONCLUSIONS
  Thus, in NHCM dominated diastolic dysfunction of hypertrophic type. Such dysfunction defining a clinic cardiac deficiency or syncope. One third of the patients had pseudonormal transmitral flow type, difficult to assess diastolic function. Diastolic dysfunction in NHCM was combined with impaired contractility of the walls of ventricle.
authors: D V
authors: DV
authors: Bogdanov
mesh_terms: D000328:Adult; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications / Q000503:physiopathology*; D003971:Diastole / Q000502:physiology; D054144:Heart Failure, Diastolic / Q000209:etiology / Q000503:physiopathology; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016277:Ventricular Function, Left