title: Evaluation of GC-ICP-MS/MS as a New Strategy for Specific Heteroatom Detection of Phosphorus, Sulfur, and Chlorine Determination in Foods.
abstract: For the first time in the literature, application of a GC-ICP-MS/MS method for the selective and sensitive detection of specific heteroatoms of phosphorus, sulfur, and chlorine has been accomplished. As a proof of concept, organophosphorus, organosulfur, and organochlorine pesticides in various food matrices have been studied. For the detection of organophosphorus and organosulfur pesticides, oxygen was used in the collision reaction cell (CRC) to convert P (m/z 31) to PO(+) (m/z 47) and S (m/z 32) to SO(+) (m/z 48). Similarly, ClH2(+) (m/z 37) was monitored after the reaction of Cl (m/z 35) with hydrogen in the CRC for the determination of organochlorine pesticides. Real food samples (baby food purees, fresh vegetables, loose tea) were screened for their pesticide content, following preparation of triplicate extracts using QuEChERS (quick, easy, cheap, effective, rugged, and safe). Excellent linearity with correlation coefficients R ≥ 0.997 was achieved, and the lowest detection limits obtained for the organophosphorus, organosulfur, and organochlorine pesticides were 0.0005, 0.675, and 0.144 μg/kg, respectively.
authors: §Agilent Technologies, Inc., 5301 Stevens Creek Boulevard, Santa Clara, California 95051, United States.
authors: Jenny
authors: J
authors: Nelson
authors: #HM Clause, 9241 Mace Boulevard, Davis, California 95618, United States.
authors: Helene
authors: H
authors: Hopfer
authors: §Agilent Technologies, Inc., 5301 Stevens Creek Boulevard, Santa Clara, California 95051, United States.
authors: Fabio
authors: F
authors: Silva
authors: §Agilent Technologies, Inc., 5301 Stevens Creek Boulevard, Santa Clara, California 95051, United States.
authors: Steve
authors: S
authors: Wilbur
authors: §Agilent Technologies, Inc., 5301 Stevens Creek Boulevard, Santa Clara, California 95051, United States.
authors: Jianmin
authors: J
authors: Chen
authors: §Agilent Technologies, Inc., 5301 Stevens Creek Boulevard, Santa Clara, California 95051, United States.
authors: Kumi
authors: K
authors: Shiota Ozawa
authors: ⊥Agilent Technologies, Inc., 2850 Centerville Road, Wilmington, Delaware 19808, United States.
authors: Philip L
authors: PL
authors: Wylie
mesh_terms: D002713:Chlorine / Q000032:analysis*; D002849:Chromatography, Gas / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D007225:Infant Food / Q000032:analysis; D057230:Limit of Detection; D010573:Pesticide Residues / Q000032:analysis*; D010758:Phosphorus / Q000032:analysis*; D013455:Sulfur / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D013662:Tea / Q000737:chemistry; D014675:Vegetables / Q000737:chemistry
chemical_list: D010573:Pesticide Residues; D013662:Tea; D010758:Phosphorus; D002713:Chlorine; D013455:Sulfur
keywords: GC-ICP-MS/MS; organochlorine; organophosphorus; organosulfur; pesticide