title: Effect of late-onset fetal growth restriction on organization of behavioral state in infants.
abstract: BACKGROUND
  The aim of this study was to analyze whether late-onset fetal growth restriction (FGR) alters regulatory capability in infants, and whether this can be detected using both the neonatal behavior assessment scale (NBAS) and brainstem auditory-evoked potentials (BAEP).
  
  
  METHODS
  The diagnosis of FGR was made on Doppler examination in the third trimester of pregnancy. NBAS and BAEP measurement were performed at 1 month of corrected postnatal age.
  
  
  RESULTS
  The group with late-onset FGR was integrated with 17 infants and the control group consisted of 14 subjects. The NBAS range of state score, which reflects organization of behavioral state, was low in infants with late-onset FGR. No differences were found in BAEP between groups. No association between NBAS and BAEP was detected.
  
  
  CONCLUSIONS
  Late-onset FGR has a deleterious effect on NBAS range of state, but possibly does not alter BAEP response. It is proposed that regulatory capabilities in the neonatal period play a primary role in subtle cognitive difficulties in infants with late-onset FGR in the long term.
authors: Faculty of Psychology, National Autonomous University of Mexico (UNAM).|Department of Developmental Neurobiology, National Institute of Perinatology (INper).|School of Psychology of Panamericana University (UP), Mexico City, Mexico.
authors: Vania
authors: V
authors: Aldrete-Cortez
authors: Department of Developmental Neurobiology, National Institute of Perinatology (INper).
authors: Lourdes
authors: L
authors: Schnaas
authors: Clinic of Sleep Disorders, National Autonomous University of Mexico (UNAM).|Department of Neurological Rehabilitation, Subdivision of Neurobiology, National Institute of Rehabilitation.
authors: Adrián
authors: A
authors: Poblano
authors: Department of Neuroscience, Subdivision of Neurobiology, National Institute of Rehabilitation.
authors: Paul
authors: P
authors: Carrillo-Mora
authors: Department of Perinatal Neurology, National Institute of Perinatology (INper).
authors: Efraín
authors: E
authors: Olivas-Peña
authors: Department of Maternal-Fetal Medicine, National Institute of Perinatology (INper).
authors: Juan Carlos
authors: JC
authors: Bello-Muñoz
authors: Department of Maternal-Fetal Medicine, National Institute of Perinatology (INper).
authors: Mario
authors: M
authors: Guzmán-Huerta
authors: Ministry of Health (SSA), Coordination of National Institutes of Health and High-Specialization Hospitals, Mexico.
authors: Armando
authors: A
authors: Mansilla-Olivares
mesh_terms: D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D015994:Incidence; D018730:Infant Behavior; D007231:Infant, Newborn; D008297:Male; D008800:Mexico / Q000453:epidemiology; D011247:Pregnancy; D012189:Retrospective Studies; D013997:Time Factors; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal; D055815:Young Adult
keywords: Brazelton neonatal behavioral assessment scale; brainstem auditory-evoked potential; fetal growth restriction; self- regulation