title: Survival of pregnancies with small for gestational age detected before 24 weeks gestation.
abstract: OBJECTIVE
  Counselling women where severe growth abnormalities are detected early in the pregnancy is often difficult due to a paucity of outcome data of this specific subset of early onset disease. This study therefore aimed to assess the outcome of pregnancies where an estimated fetal weight less than the third centile were detected prior to 24 weeks gestation.
  
  
  METHODS
  A retrospective study in two London teaching hospitals, over an eight year period was performed, analysing all pregnancies with an ultrasound estimated fetal weight less than the third centile prior to 24 weeks gestation. Outcome data: intrauterine death, neonatal death, survival to discharge, gestation at delivery and birthweight were collected.
  
  
  RESULTS
  Out of 20 pregnancies included in the analysis, six died in utero, two died in the neonatal period and 12 (60%) survived until discharge. Of the livebirths, 67% delivered preterm and 100% percent of livebirths were delivered by Caesarean Section.
  
  
  CONCLUSIONS
  When severe growth abnormalities were detected before 24 weeks, more than half of pregnancies resulted in survival to neonatal discharge. There was an increased incidence of preterm delivery, caesarean section and neonatal unit admission. This information is useful in counselling parents.
authors: Fetal Medicine Unit, St Thomas's Hospital, Lambeth Palace Road, London SE1 7EH, UK.
authors: Lisa
authors: L
authors: Story
authors: Fetal Medicine Unit, St Thomas's Hospital, Lambeth Palace Road, London SE1 7EH, UK. Electronic address: Srividhya.Sankaran@gstt.nhs.uk.
authors: Srividhya
authors: S
authors: Sankaran
authors: Centre for Fetal Care, Queen Charlotte and Chelsea Hospital, London W12 0HS, UK.
authors: Edward
authors: E
authors: Mullins
authors: Neonatal Unit, St Thomas's Hospital, London, SE1 7EH, UK.
authors: Su
authors: S
authors: Tan
authors: Neonatal Unit, St Thomas's Hospital, London, SE1 7EH, UK.
authors: Glynn
authors: G
authors: Russell
authors: Centre for Fetal Care, Queen Charlotte and Chelsea Hospital, London W12 0HS, UK; Mater Research Institute-University of Queensland, Australia.
authors: Sailesh
authors: S
authors: Kumar
authors: Fetal Medicine Unit, St Thomas's Hospital, Lambeth Palace Road, London SE1 7EH, UK.
authors: Pippa
authors: P
authors: Kyle
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D002585:Cesarean Section; D005260:Female; D005313:Fetal Death; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging* / Q000503:physiopathology; D020567:Fetal Weight; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D050498:Live Birth; D066087:Perinatal Death; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D047928:Premature Birth / Q000209:etiology; D012189:Retrospective Studies; D015996:Survival Rate; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal; D055988:Uterine Artery / Q000502:physiology
keywords: Early onset; Estimated fetal weight; Fetal growth restriction; Small for gestational age