title: Laser CO2treatment for vulvar lymphedema secondary to gynecological cancer therapy: A report of two cases and review of the literature.
abstract: Vulvar lymphedema is an uncommon and disabling side-effect of pelvic lymphadenectomy and pelvic radiotherapeutic treatment for invasive genital cancer. Lymphorrhea, a complication of lymphedema, may be extremely distressing for patients due to the requirement to wear sanitary towels and as the pain and loss of elasticity of the vulvar skin and mucosa can cause discomfort during coitus. Surgical treatments of lymphorrhea and vulvar lymphedema secondary to gynecological cancer treatments remain controversial and are not currently considered to be the standard therapy. The present study reports two cases of vulvar lymphedema complicated by vulvar lymphorrhea in females who had undergone treatment for cervical and endometrial cancer, respectively; a review of the literature is also included. In the two present cases, vulvar lymphedemas were refractory to standard treatments, including decongestive therapy, manual lymph drainage, elastic bandaging, low-stretch bandaging, exercises and skin care. Laser CO2excision and vaporization of the whole skin and mucosal tissue of the vulva was successfully performed to treat the lymphorrhea and improve quality of life. Thus, the present two cases indicated that laser CO2surgery may present an additional therapy for the treatment of genital lymphedema that is refractory to other treatments.
authors: Department of Gynecological Oncology, Oncological Referral Center, National Cancer Institute, Aviano, Pordenone 33081, Italy.
authors: Francesco
authors: F
authors: Sopracordevole
authors: Department of Woman's Health Sciences, Polytechnic University of Marche, Ancona 60123, Italy.
authors: Francesca
authors: F
authors: Mancioli
authors: Division of Pathology, Oncological Referral Center, National Cancer Institute, Aviano, Pordenone 33081, Italy.
authors: Vincenzo
authors: V
authors: Canzonieri
authors: Department of Gynecological Oncology, Oncological Referral Center, National Cancer Institute, Aviano, Pordenone 33081, Italy.
authors: Monica
authors: M
authors: Buttignol
authors: Department of Gynecological Oncology, Oncological Referral Center, National Cancer Institute, Aviano, Pordenone 33081, Italy.
authors: Giorgio
authors: G
authors: Giorda
authors: Department of Woman's Health Sciences, Polytechnic University of Marche, Ancona 60123, Italy.
authors: Andrea
authors: A
authors: Ciavattini
keywords: lymphorrhea; pelvic lymphadenectomy; pelvic radiotherapy; vulvar lymphedema