title: [Dynamics of the hemostasis parameters in patients with arterial hypertension in treatment with combined antihypertensive agents].
abstract: The paper represents the dynamics of hemostasis values in 42 patients with arterial hypertension of the second stage in complex treatment with combined drug tonorma (atenolon - 100 mg, nifedipine - 10 mg, chlorthalidone - 25 mg). It was established thatthe administration of a dose of 0.5-1 of tonorma tablet once a day for 30 days improves subjective state of patients: helps to normalize blood pressure, reduce headaches, dizziness, frequency of angina pectoris, diminishes malaise. The study of hemostasis parameters in patients with the second stage of AH had revealed imbalance of the following: increased coagulation activity, decreased anticoagulant and fibrinolytic systems activity. The application of the combined drug tonorma promotes normalization of blood coagulation.
authors: Ie Kh
authors: IeKh
authors: Zaremba
authors: M S
authors: MS
authors: Bula
authors: O V
authors: OV
authors: Zaremba-Fedchyshyn
authors: O V
authors: OV
authors: Zaremba
authors: M M
authors: MM
authors: Virna
mesh_terms: D000959:Antihypertensive Agents / Q000008:administration & dosage*; D001794:Blood Pressure / Q000187:drug effects; D002752:Chlorthalidone / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D006487:Hemostasis / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000008:administration & dosage*
chemical_list: D000959:Antihypertensive Agents; D004338:Drug Combinations; D009543:Nifedipine; D002752:Chlorthalidone