title: Motionless electromagnetic phase stepping versus mechanical phase stepping in x-ray phase-contrast imaging with a compact source.
abstract: X-ray phase contrast imaging based on grating interferometers detects the refractive index distribution of an object without relying on radiation attenuation, thereby having the potential for reduced radiation absorption. These techniques belong to the broader category of optical wavefront measurement, which requires stepping the phase of the interference pattern to obtain a pixel-wise map of the phase distortion of the wavefront. While phase stepping traditionally involves mechanical scanning of a grating or mirror, we developed electromagnetic phase stepping (EPS) for imaging with compact sources to obviate the need for mechanical movement. In EPS a solenoid coil is placed outside the x-ray tube to shift its focal spot with a magnetic field, causing a relative movement between the projection of the sample and the interference pattern in the image. Here we present two embodiments of this method. We verified experimentally that electromagnetic and mechanical phase stepping give the same results and attain the same signal-to-noise ratios under the same radiation dose. We found that the relative changes of interference fringe visibility were within 3.0% when the x-ray focal spot was shifted by up to 1.0 mm in either direction. We conclude that when using x-ray tube sources, EPS is an effective means of phase stepping without the need for mechanical movement.
authors: Imaging Physics Laboratory, Biochemistry and Biophysics Center, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors: Katherine J
authors: KJ
authors: Harmon
authors: Houxun
authors: H
authors: Miao
authors: Andrew A
authors: AA
authors: Gomella
authors: Eric E
authors: EE
authors: Bennett
authors: Barbara A
authors: BA
authors: Foster
authors: Priya
authors: P
authors: Bhandarkar
authors: Han
authors: H
authors: Wen
mesh_terms: D055590:Electromagnetic Phenomena; D008858:Microscopy, Phase-Contrast / Q000295:instrumentation / Q000379:methods; D009038:Motion; D011859:Radiography / Q000295:instrumentation / Q000379:methods*; D059629:Signal-To-Noise Ratio; D014965:X-Rays