title: HLA-A, -B, -C, and -DRB1 genotyping of 1000 Northern Irish individuals from Belfast, Northern Ireland in the United Kingdom.
abstract: One thousand individuals from Belfast, Northern Ireland were genotyped at the HLA-A, -B, -C and -DRB1 loci using sequence-specific oligonucleotide probe methods. HLA-A locus genotypes display a minor Hardy-Weinberg (HW) deviation (p=0.0375); HLA-B, -C and -DRB1 genotypes are consistent with expected HW proportions. These genotype data are available in the Allele Frequencies Net Database under identifier AFND 1243.
authors: Northern Ireland Histocompatibility and Immunogenetics Laboratory, Belfast City Hospital, Belfast, Northern Ireland, UK.
authors: Williams
authors: W
authors: Fionnuala
authors: Transplant Immunology, Royal Liverpool Hospital, Liverpool, UK. Electronic address: Derek.Middleton@rlbuht.nhs.uk.
authors: Middleton
authors: M
authors: Derek
mesh_terms: D000483:Alleles; D005787:Gene Frequency; D056426:Genetic Loci; D005828:Genetics, Population; D015894:Genome, Human; D060005:Genotyping Techniques; D015234:HLA-A Antigens / Q000145:classification / Q000235:genetics* / Q000276:immunology; D015235:HLA-B Antigens / Q000145:classification / Q000235:genetics* / Q000276:immunology; D015236:HLA-C Antigens / Q000145:classification / Q000235:genetics* / Q000276:immunology; D059811:HLA-DRB1 Chains / Q000145:classification / Q000235:genetics* / Q000276:immunology; D006801:Humans; D009660:Northern Ireland
chemical_list: D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D059811:HLA-DRB1 Chains