title: Screening and surveillance CT abdomen/pelvis for metastases in patients with soft-tissue sarcoma of the extremity.
abstract: OBJECTIVE
  The clinical utility of routine cross sectional imaging of the abdomen and pelvis in the screening and surveillance of patients with primary soft-tissue sarcoma of the extremities for metastatic disease is controversial, based on its questionable yield paired with concerns regarding the risks of radiation exposure, cost, and morbidity resulting from false positive findings.
  
  
  METHODS
  Through retrospective review of 140 patients of all ages (mean 53 years; 2 to 88) diagnosed with soft-tissue sarcoma of the extremity with a mean follow-up of 33 months (0 to 291), we sought to determine the overall incidence of isolated abdominopelvic metastases, their temporal relationship to chest involvement, the rate of false positives, and to identify disparate rates of metastases based on sarcoma subtype.
  
  
  RESULTS
  A total of four patients (2.9%) exhibited isolated abdominopelvic metastatic disease during the surveillance period. In all cases of concomitant chest and abdominopelvic disease, chest involvement preceded abominopelvic involvement. There was a significant false positive rate requiring invasive workup.
  
  
  CONCLUSIONS
  In the setting of a relative paucity of evidence concerning a rare disease process and in difference to recently published investigations, we add a clinical cohort not supportive of routine cross sectional imaging of the abdomen and pelvis. Cite this article: Bone Joint Res 2015;4:45-9.
authors: Virginia Commonwealth University Medical Center, P.O. Box 980153, Richmond, Virginia 23298-0153, USA.
authors: M J
authors: MJ
authors: Thompson
authors: Virginia Commonwealth University Medical Center, P.O. Box 980153, Richmond, Virginia 23298-0153, USA.
authors: J
authors: J
authors: Ross
authors: Virginia Commonwealth University Medical Center, P.O. Box 980153, Richmond, Virginia 23298-0153, USA.
authors: G
authors: G
authors: Domson
authors: Virginia Commonwealth University Medical Center, P.O. Box 980153, Richmond, Virginia 23298-0153, USA.
authors: W
authors: W
authors: Foster
keywords: Computed tomography; Metastatic disease; Screening; Soft-tissue sarcoma; surveillance