title: Long-term patency of endoscopically harvested radial arteries: from a randomized controlled trial.
abstract: OBJECTIVE
  From 2005 to 2007, 119 patients were enrolled in a prospective randomized controlled trial comparing open and endoscopically harvested radial arteries for coronary artery bypass grafting. The objective of the current study was to compare graft patency between intervention groups at more than 5 years from the initial trial. We hypothesized that endoscopically harvested radial arteries would show equivalent patency to those conventionally harvested.
  
  
  METHODS
  At 5 years or greater from their operation, all consenting patients underwent a single-day anatomic and functional cardiac assessment with coronary computed tomography angiography and sestamibi myocardial perfusion scanning. Medical Outcomes Study 36-Item Short-Form Health Surveys and Seattle Angina Questionnaires were completed to assess the overall quality of life. All patients had received calcium channel blocker therapy for at least 6 months postoperatively.
  
  
  RESULTS
  The mean (SD) duration of follow-up was 79.2 (8.6) months for all patients. One death occurred within 30 days of coronary artery bypass grafting in each treatment group, and eight additional noncardiac deaths occurred during the study time frame. Of 119 patients, 66 consented to follow-up. Thirty-two had open radial artery harvest, and 34 had endoscopic radial artery harvest. At more than 5 years, there were 28 patent conventionally harvested radial arteries (87.5%) and 31 patent endoscopically harvested radial arteries (91.2%) (P = 0.705). Measured quality of life was comparable between groups.
  
  
  CONCLUSIONS
  Endoscopic radial artery harvest is safe and effective when compared with open radial artery harvest, with excellent graft patency demonstrated at more than 5 years. Patency results are noninferior in endoscopic radial artery harvest.
authors: From the *Division of Cardiac Surgery, Department of Surgery, and †Division of Nuclear Medicine, Department of Medical Imaging, Western University, London Health Sciences Centre, London, Ontario, Canada.
authors: Daniel J P
authors: DJ
authors: Burns
authors: Stuart A
authors: SA
authors: Swinamer
authors: Stephanie A
authors: SA
authors: Fox
authors: Jonathan
authors: J
authors: Romsa
authors: William
authors: W
authors: Vezina
authors: Cigdem
authors: C
authors: Akincioglu
authors: James
authors: J
authors: Warrington
authors: Lin-Rui
authors: LR
authors: Guo
authors: Michael W A
authors: MW
authors: Chu
authors: Mackenzie A
authors: MA
authors: Quantz
authors: Richard J
authors: RJ
authors: Novick
authors: Bob
authors: B
authors: Kiaii
mesh_terms: D002121:Calcium Channel Blockers / Q000627:therapeutic use; D017023:Coronary Angiography / Q000379:methods; D001026:Coronary Artery Bypass / Q000379:methods*; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D011446:Prospective Studies; D011788:Quality of Life; D017534:Radial Artery / Q000637:transplantation*; D012501:Saphenous Vein / Q000637:transplantation; D020858:Tissue and Organ Harvesting / Q000379:methods*; D016896:Treatment Outcome; D014654:Vascular Patency
chemical_list: D002121:Calcium Channel Blockers