title: Angiosome-directed revascularization for critical limb ischemia.
abstract: The angiosome hypothesis states that the surface of the lower extremity is supplied by arteries consistently corresponding to regions of the foot. There is limited and conflicting evidence suggesting that angiosome-directed interventions improve wound healing and limb salvage. As peripheral arterial disease progresses, collaterals may develop that confound a predetermined angiosome map. In selecting a revascularization target vessel for patients with tissue loss, good surgical judgment should prevail, including consideration of the angiosome concept to optimize tissue healing.
authors: Division of Vascular and Endovascular Surgery, Sulpizio Cardiovascular Center, University of California-San Diego School of Medicine, 9434 Medical Center Drive, Mail Code 7403, La Jolla, CA 92037.
authors: John C
authors: JC
authors: McCallum
authors: Division of Vascular and Endovascular Surgery, Sulpizio Cardiovascular Center, University of California-San Diego School of Medicine, 9434 Medical Center Drive, Mail Code 7403, La Jolla, CA 92037. Electronic address: j1lane@ucsd.edu.
authors: John S
authors: JS
authors: Lane
mesh_terms: D001158:Arteries / Q000033:anatomy & histology / Q000503:physiopathology; D003097:Collateral Circulation; D016638:Critical Illness; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D023821:Limb Salvage; D035002:Lower Extremity / Q000098:blood supply*; D008955:Models, Cardiovascular; D012039:Regional Blood Flow; D016896:Treatment Outcome; D014945:Wound Healing