title: Differential metabolic and coexpression networks of plant metabolism.
abstract: Recent analyses have demonstrated that plant metabolic networks do not differ in their structural properties and that genes involved in basic metabolic processes show smaller coexpression than genes involved in specialized metabolism. By contrast, our analysis reveals differences in the structure of plant metabolic networks and patterns of coexpression for genes in (non)specialized metabolism. Here we caution that conclusions concerning the organization of plant metabolism based on network-driven analyses strongly depend on the computational approaches used.
authors: Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, Potsdam, Germany; Institute of Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
authors: Nooshin
authors: N
authors: Omranian
authors: Targenomix GmbH, Am Mühlenberg 11, Potsdam, Germany.
authors: Sabrina
authors: S
authors: Kleessen
authors: Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, Potsdam, Germany.
authors: Takayuki
authors: T
authors: Tohge
authors: Targenomix GmbH, Am Mühlenberg 11, Potsdam, Germany.
authors: Sebastian
authors: S
authors: Klie
authors: Estación Experimental del Zaidín CSIC, 18008 Granada, Spain.
authors: Georg
authors: G
authors: Basler
authors: Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, Potsdam, Germany; Institute of Biochemistry and Biology, University of Potsdam, Potsdam, Germany.
authors: Bernd
authors: B
authors: Mueller-Roeber
authors: Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, Potsdam, Germany.
authors: Alisdair R
authors: AR
authors: Fernie
authors: Max Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, Potsdam, Germany. Electronic address: nikoloski@mpimp-golm.mpg.de.
authors: Zoran
authors: Z
authors: Nikoloski
mesh_terms: D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant / Q000235:genetics / Q000502:physiology; D053263:Gene Regulatory Networks / Q000235:genetics / Q000502:physiology; D010944:Plants / Q000235:genetics / Q000378:metabolism*
keywords: differential network analysis; gene coexpression; metabolic networks; plant specialized metabolism