title: Iridium-catalyzed single-step N-substituted lactam synthesis from lactones and amines.
abstract: Catalytic lactam synthesis was achieved directly from lactones and amines using an Ir catalyst. Three sequential transformations—aminolysis of lactone, N-alkylation of amine with hydroxyamide, and intramolecular transamidation of aminoamide—afforded the corresponding N-substituted lactams.
authors: Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Korea.
authors: Kicheol
authors: K
authors: Kim
authors: Department of Chemistry, College of Natural Sciences, Seoul National University, Seoul 151-747, Korea.
authors: Soon Hyeok
authors: SH
authors: Hong