title: Photolithographic patterning of 3D-formed polycarbonate films for targeted cell guiding.
abstract: A facile photolithographic platform for the design of cell-guiding polymeric substrates is introduced. Specific areas of the substrate are photo-deactivated for the subsequent growth of bioresistant polymer brushes, creating zones for cell proliferation, and protein adhesion.
authors: Soft Matter Synthesis Laboratory, Institute for Biological Interfaces (IBG), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany; Preparative Macromolecular Chemistry Institut für Technische Chemie und Polymerchemie, Karlsruhe Institute of Technology (KIT) Engesserstr. 18, 76128, Karlsruhe, Germany.
authors: Astrid F
authors: AF
authors: Hirschbiel
authors: Simone
authors: S
authors: Geyer
authors: Basit
authors: B
authors: Yameen
authors: Alexander
authors: A
authors: Welle
authors: Pavel
authors: P
authors: Nikolov
authors: Stefan
authors: S
authors: Giselbrecht
authors: Steffen
authors: S
authors: Scholpp
authors: Guillaume
authors: G
authors: Delaittre
authors: Christopher
authors: C
authors: Barner-Kowollik
mesh_terms: D000818:Animals; D057219:Biofouling; D002417:Cattle; D002448:Cell Adhesion; D002460:Cell Line; D049109:Cell Proliferation; D004548:Elasticity; D005347:Fibroblasts / Q000502:physiology; D049452:Green Fluorescent Proteins / Q000737:chemistry / Q000378:metabolism; D008689:Methacrylates / Q000737:chemistry; D055668:Photochemical Processes; D011076:Polycarboxylate Cement / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry; D044967:Serum / Q000737:chemistry / Q000502:physiology; D013499:Surface Properties; D014466:Ultraviolet Rays; D015027:Zebrafish
chemical_list: D008689:Methacrylates; D011076:Polycarboxylate Cement; C485184:enhanced green fluorescent protein; C524499:polyethylene glycol methacrylate; D049452:Green Fluorescent Proteins; C005506:polycarbonate; D011092:Polyethylene Glycols
keywords: antifouling polymer brushes; cell guiding; photopatterning; polycarbonate films