title: Epidemiology of Mycoplasma acquisition in male HIV-1 infected patients: a multistage cross-sectional survey in Jiangsu, China.
abstract: Mycoplasma infections are most frequently associated with disease in the urogenital or respiratory tracts and, in most cases, mycoplasmas infect the host persistently. In HIV-infected individuals the prevalence and role of genital mycoplasmas has not been well studied. To investigate the six species of Mycoplasma and the risk factors for infection in Jiangsu province, first-void urine and venous blood samples were collected and epidemiological questionnaires were administered after informed consent. A total of 1541 HIV/AIDS patients were recruited in this study. The overall infection rates of six Mycoplasma species were: Ureaplasma urealyticum (26·7%), Mycoplasma hominis (25·3%), M. fermentans (5·1%), M. genitalium (20·1%), M. penetrans (1·6%) and M. pirum (15·4%). The Mycoplasma infection rate in the unmarried group was lower than that of the married, divorced and widowed groups [adjusted odds ratio (aOR) 1·432, 95% confidence interval (CI) 1·077-1·904, P < 0·05]. The patients who refused highly active antiretroviral therapy (HAART) had a much higher risk of Mucoplasma infection (aOR 1·357, 95% CI 1·097-1·679, P < 0·05). Otherwise, a high CD4+ T cell count was a protective factor against Mycoplasma infection (aOR 0·576, 95% CI 0·460-0·719, P < 0·05). Further research will be required to confirm a causal relationship and to identify risk factors for Mycoplasma infection in HIV/AIDS populations.
authors: Key Laboratory of Environmental Medicine and Engineering, Ministry of Education;Department of Epidemiology and Statistics,School of Public Health, Southeast University,Nanjing,Jiangsu,People's Republic of China.
authors: L-S
authors: LS
authors: Chen
authors: Key Laboratory of Environmental Medicine and Engineering, Ministry of Education;Department of Epidemiology and Statistics,School of Public Health, Southeast University,Nanjing,Jiangsu,People's Republic of China.
authors: J-R
authors: JR
authors: Wu
authors: Key Laboratory of Environmental Medicine and Engineering, Ministry of Education;Department of Epidemiology and Statistics,School of Public Health, Southeast University,Nanjing,Jiangsu,People's Republic of China.
authors: B
authors: B
authors: Wang
authors: Key Laboratory of Environmental Medicine and Engineering, Ministry of Education;Department of Epidemiology and Statistics,School of Public Health, Southeast University,Nanjing,Jiangsu,People's Republic of China.
authors: T
authors: T
authors: Yang
authors: Key Laboratory of Environmental Medicine and Engineering, Ministry of Education;Department of Epidemiology and Statistics,School of Public Health, Southeast University,Nanjing,Jiangsu,People's Republic of China.
authors: R
authors: R
authors: Yuan
authors: Key Laboratory of Environmental Medicine and Engineering, Ministry of Education;Department of Epidemiology and Statistics,School of Public Health, Southeast University,Nanjing,Jiangsu,People's Republic of China.
authors: Y-Y
authors: YY
authors: Zhao
authors: Jiangsu Centers for Diseases Prevention and Control,Nanjing,Jiangsu,People's Republic of China.
authors: J-S
authors: JS
authors: Xu
authors: Jiangsu Centers for Diseases Prevention and Control,Nanjing,Jiangsu,People's Republic of China.
authors: H-X
authors: HX
authors: Guo
authors: Jiangsu Centers for Diseases Prevention and Control,Nanjing,Jiangsu,People's Republic of China.
authors: X-P
authors: XP
authors: Huan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D023241:Antiretroviral Therapy, Highly Active / Q000706:statistics & numerical data*; D002681:China / Q000453:epidemiology; D060085:Coinfection / Q000453:epidemiology; D003430:Cross-Sectional Studies; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology*; D015497:HIV-1; D006801:Humans; D008297:Male; D017533:Marital Status / Q000706:statistics & numerical data*; D008875:Middle Aged; D009174:Mycoplasma / Q000235:genetics / Q000302:isolation & purification; D009175:Mycoplasma Infections / Q000453:epidemiology* / Q000382:microbiology; D016858:Mycoplasma fermentans / Q000235:genetics / Q000302:isolation & purification; D045704:Mycoplasma genitalium / Q000235:genetics / Q000302:isolation & purification; D019535:Mycoplasma hominis / Q000235:genetics / Q000302:isolation & purification; D018661:Mycoplasma penetrans / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D015995:Prevalence; D012307:Risk Factors; D016869:Ureaplasma Infections / Q000453:epidemiology*; D016990:Ureaplasma urealyticum / Q000235:genetics / Q000302:isolation & purification; D055815:Young Adult
keywords: HIV; mycoplasmas; prevalence