title: Quality of life and psychological morbidity in vitiligo patients: a study in a teaching hospital from north-East India.
abstract: BACKGROUND
  Vitiligo is an acquired discoloration of skin and mucous membrane of great cosmetic importance affecting 1-4% of the world's population. It causes disfiguration in all races, more so in dark-skinned people because of strong contrast. Men, women, and children with vitiligo face severe psychological and social disadvantage.
  
  
  OBJECTIVE
  To assess the impact of the disease on the quality of life of patients suffering from vitiligo, also to ascertain any psychological morbidity like depression associated with the disease and to compare the results with that of healthy control group.
  
  
  METHODS
  Dermatology Life Quality Index (DLQI) and Hamilton Depression Rating Scale (HAMD) are administered to 100 vitiligo patients presenting to the Dermatology OPD and 50 age- and sex-matched healthy controls. Results were analyzed and compared with that of control group. Findings are also correlated in relation to demographic and clinical profile of the disease. Statistical analysis is made to see the significance.
  
  
  RESULTS
  Vitiligo-affected patients had significantly elevated total DLQI scores (P < 0.001) compared to healthy controls. There is increase in parameters like itch, embarrassment, social and leisure activities in the patient cohort than the control group. Patients of vitiligo are also found to be more depressed (P < 0.001) than the controls.
  
  
  CONCLUSIONS
  Quality of life (QOL) in patients affected with vitiligo declined more severely, and also there is increase in incidence of depression than in the control group. These changes are critical for the psychosocial life of the affected people.
authors: Department of Dermatology, Gauhati Medical College and Hospital, Guahati, Assam, India.
authors: Lucybeth N
authors: LN
authors: Sangma
authors: Department of Dermatology, Gauhati Medical College and Hospital, Guahati, Assam, India.
authors: Jyoti
authors: J
authors: Nath
authors: Department of Psychiatry, Gauhati Medical College and Hospital, Guahati, Assam, India.
authors: Dipesh
authors: D
authors: Bhagabati
keywords: DLQI; Depression; HAMD; vitiligo