title: Fasting does not induce gastric emptying in rats.
abstract: OBJECTIVE
  To evaluate the effect of fasting on gastric emptying in mice.
  
  
  METHODS
  Twenty-eight mice were distributed into three study groups: a normal group (N=4): normal standard animals; a total fasting group (N=12): subjected to food and water deprivation and a partial fasting group (N=12): subjected to food deprivation only. The fasting groups were subdivided into three subgroups of four animals each, according to the date of euthanasia: 24, 48 and 72 hours. Was analyzed: the gastric volume, degree of the gastric wall distention and the presence of food debris in gastrointestinal tract.
  
  
  RESULTS
  The mean gastric volume was 1601 mm3 in the normal group, 847 mm3 in total fasting group and 997 mm3 in partial fasting group. There was difference between the fasting groups in any analyzed period (p<0.05). Regarding the presence of food debris in the gastrointestinal tract and the degree of distension of the stomach, there was no difference between the groups that underwent total or partial fasting (p>0.05).
  
  
  CONCLUSIONS
  Total fasting or only-solids deprivation does not induce gastric emptying in mice.
authors: Department of Integrate Health, Medical School, University State of Para, Brazil.
authors: Marcus Vinicius Henriques
authors: MV
authors: Brito
authors: Department of General Surgery, UEPA, Brazil.
authors: Edson Yuzur
authors: EY
authors: Yasojima
authors: School of Medicine, UEPA, Brazil.
authors: Renan Kleber Costa
authors: RK
authors: Teixeira
authors: School of Medicine, UEPA, Brazil.
authors: Abdallah de Paula
authors: Ade P
authors: Houat
authors: School of Medicine, UEPA, Brazil.
authors: Vitor Nagai
authors: VN
authors: Yamaki
authors: School of Medicine, UEPA, Brazil.
authors: Felipe Lobato da Silva
authors: FL
authors: Costa
mesh_terms: D000818:Animals; D001835:Body Weight; D005215:Fasting / Q000502:physiology*; D005260:Female; D005508:Food Deprivation / Q000502:physiology; D005746:Gastric Emptying / Q000502:physiology*; D041981:Gastrointestinal Tract / Q000502:physiology; D051379:Mice; D011300:Preoperative Care / Q000379:methods; D011897:Random Allocation; D012016:Reference Values; D013997:Time Factors