title: Test-Retest Repeatability of Microperimetry at the Border of Deep Scotomas.
abstract: OBJECTIVE
  The purpose of this study was to examine the test-retest repeatability of microperimetric sensitivity at the border of deep scotomas.
  
  
  METHODS
  Thirty normal participants underwent two examinations, each on the Macular Integrity Assessment (MAIA) microperimeter and on the MP-1 microperimeter (four examinations in total). A customized stimulus pattern allowed microperimetric sensitivity to be measured at the border of the optic nerve head (ONH), which acted as a model for the border of a deep scotoma-and also at the macular and peripapillary region.
  
  
  RESULTS
  There were no significant changes in average point-wise sensitivity (PWS) values between the two examinations for all three regions using the MAIA microperimeter (P ≥ 0.262). The PWS coefficient of repeatability (CoR) was ±12.99 dB at the border of the ONH, which was significantly larger than points in the macular and peripapillary regions (P > 0.001). A significant decrease in average PWS, using the MP-1 microperimeter at the macular and peripapillary region (P < 0.001), meant that the PWS CoR could not be determined in these regions. No significant changes in average PWS were observed at the border of the ONH (P = 0.223), and the PWS CoR was ±7.52 dB in this region.
  
  
  CONCLUSIONS
  Microperimetric test-retest repeatability at the border of a deep scotoma was worse than at other areas of normal retina, and this highlights the limitation of applying a single estimate of test-retest repeatability to determine whether significant functional decline has occurred at the border of a deep scotoma.
authors: Zhichao
authors: Z
authors: Wu
authors: Chang J
authors: CJ
authors: Jung
authors: Lauren N
authors: LN
authors: Ayton
authors: Chi D
authors: CD
authors: Luu
authors: Robyn H
authors: RH
authors: Guymer
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D015203:Reproducibility of Results; D012607:Scotoma / Q000175:diagnosis* / Q000503:physiopathology; D014792:Visual Acuity; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields; D055815:Young Adult