title: Systemic corticosteroid therapy for acute sinusitis.
abstract: OBJECTIVE
  Are oral or parenteral corticosteroids associated with improved clinical outcomes in patients with acute sinusitis compared with placebo or nonsteroidal anti-inflammatory drugs (NSAIDs)?
  
  
  CONCLUSIONS
  Oral corticosteroids combined with antibiotics may be associated with modest benefit for short-term relief of symptoms in adults with severe symptoms of acute sinusitis compared with antibiotics alone. Oral corticosteroids as monotherapy are not associated with improved clinical outcomes in adults with clinically diagnosed acute sinusitis.
authors: Division Surgical Specialties, Department of Otorhinolaryngology, University Medical Center Utrecht, the Netherlands2Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands.
authors: Roderick P
authors: RP
authors: Venekamp
authors: Department of Family Medicine, University of Washington, Seattle.
authors: Matthew J
authors: MJ
authors: Thompson
authors: Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, the Netherlands4Departments of Operating Rooms and Health Evidence, Radboud University Nijmegen Medical Centre, the Netherlands.
authors: Maroeska M
authors: MM
authors: Rovers
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006801:Humans; D012852:Sinusitis / Q000188:drug therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents