title: Simultaneous treatment (cell disruption and lipid extraction) of wet microalgae using hydrodynamic cavitation for enhancing the lipid yield.
abstract: Simultaneous treatment (combining with cell disruption and lipid extraction) using hydrodynamic cavitation (HC) was applied to Nannochloropsis salina to demonstrate a simple and integrated way to produce oil from wet microalgae. A high lipid yield from the HC (25.9-99.0%) was observed compared with autoclave (16.2-66.5%) and ultrasonication (5.4-26.9%) in terms of the specific energy input (500-10,000 kJ/kg). The optimal conditions for the simultaneous treatment were established using a statistical approach. The efficiency of the simultaneous method was also demonstrated by comparing each separate treatment. The maximum lipid yield (predicted: 45.9% and experimental: 45.5%) was obtained using 0.89% sulfuric acid with a cavitation number of 1.17 for a reaction time of 25.05 min via response surface methodology. Considering its comparable extractability, energy-efficiency, and potential for scale-up, HC may be a promising method to achieve industrial-scale microalgae operation.
authors: Department of Civil and Environmental Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea.
authors: Ilgyu
authors: I
authors: Lee
authors: Department of Civil and Environmental Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea. Electronic address: jihan@kaist.ac.kr.
authors: Jong-In
authors: JI
authors: Han
mesh_terms: D001709:Biotechnology / Q000379:methods*; D002457:Cell Extracts / Q000302:isolation & purification*; D005227:Fatty Acids / Q000032:analysis; D057446:Hydrodynamics; D008055:Lipids / Q000302:isolation & purification*; D058086:Microalgae / Q000737:chemistry*; D058009:Stramenopiles / Q000737:chemistry*; D014465:Ultrasonics
chemical_list: D002457:Cell Extracts; D005227:Fatty Acids; D008055:Lipids
keywords: Cell disruption; Hydrodynamic cavitation; Lipid extraction; Simultaneous treatment; Wet microalgae