title: Prevalence and type of associated syndromes in patients with cleft lip and cleft palate who received the treatment in Tawanchai Center until 4-5 years of age.
abstract: BACKGROUND
  Understanding the genetic etiologies of cleft lip and palate (CLP) is important for improved prevention, treatment, and prognosis for patients affected by CLP.
  
  
  OBJECTIVE
  To report the prevalence and the type of associated syndromes in Northeastern Thai patients with CLP.
  
  
  METHODS
  A retrospective study of123 cleft lip/palate children aged 4-5 years was carried out at the Tawanchai Cleft Centel; Khon Kaen University during the period from October to December 2011. Data were collected by reviewing the patient 's medical records.
  
  
  RESULTS
  Seventeen (14%) of the 123 children had multiple malformations and five (4%) of these children had associated syndromes. Syndromes were identified in 5 (29%) of the 17 children who had associated malformations. The syndromes were Apert, Cleft lip/palate-ectodermal dysplasia, Kabuki, Oculo-Auriculo-Vertebral Spectrum, and Velocardiofacial syndrome.
  
  
  CONCLUSIONS
  Recognition of the associated syndrome in a patient with CLP is essential to assess the problem of the patient, provide necessaty treatment and the appropriate methodology of prevention.
authors: Khunton
authors: K
authors: Wichajarn
authors: Ouyporn
authors: O
authors: Panamonta
authors: Suteera
authors: S
authors: Pradubwong
authors: Manat
authors: M
authors: Panamonta
authors: Wiboon
authors: W
authors: Weraarchakul
authors: Bowornsilp
authors: B
authors: Chowchuen
mesh_terms: D000015:Abnormalities, Multiple / Q000453:epidemiology*; D002675:Child, Preschool; D002971:Cleft Lip / Q000150:complications / Q000453:epidemiology*; D002972:Cleft Palate / Q000150:complications / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies; D013577:Syndrome; D013785:Thailand / Q000453:epidemiology