title: Emerging issues in antimicrobial resistance of bacteria from food-producing animals.
abstract: During the last decade, antimicrobial resistance in bacteria from food-producing animals has become a major research topic. In this review, different emerging resistance properties related to bacteria of food-producing animals are highlighted. These include: extended-spectrum β-lactamase-producing Enterobacteriaceae; carbapenemase-producing bacteria; bovine respiratory tract pathogens, such as Pasteurella multocida and Mannheimia haemolytica, which harbor the multiresistance mediating integrative and conjugative element ICEPmu1; Gram-positive and Gram-negative bacteria that carry the multiresistance gene cfr; and the occurrence of numerous novel antimicrobial resistance genes in livestock-associated methicillin-resistant Staphylococcus aureus. The emergence of the aforementioned resistance properties is mainly based on the exchange of mobile genetic elements that carry the respective resistance genes.
authors: Institute of Farm Animal Genetics, Friedrich-Loeffler-Institut, Neustadt-Mariensee, Germany.
authors: Geovana Brenner
authors: GB
authors: Michael
authors: Christin
authors: C
authors: Freitag
authors: Sarah
authors: S
authors: Wendlandt
authors: Christopher
authors: C
authors: Eidam
authors: Andrea T
authors: AT
authors: Feßler
authors: Graciela Volz
authors: GV
authors: Lopes
authors: Kristina
authors: K
authors: Kadlec
authors: Stefan
authors: S
authors: Schwarz
mesh_terms: D000818:Animals; D001419:Bacteria / Q000187:drug effects* / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics; D002417:Cattle; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D004755:Enterobacteriaceae / Q000187:drug effects / Q000235:genetics; D022761:Gene Transfer, Horizontal; D006801:Humans; D020071:Interspersed Repetitive Sequences; D058751:Livestock / Q000382:microbiology*; D016978:Mannheimia haemolytica / Q000187:drug effects / Q000235:genetics; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects / Q000235:genetics; D016979:Pasteurella multocida / Q000187:drug effects / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase
keywords: ESBL; ICE; MRSA; carbapenemase producers; horizontal gene transfer; methicillin resistance; multidrug resistance; new resistance genes