title: Diagnosis of Cushing's disease.
abstract: Diagnosis of Cushing's disease frequently remains a challenge. In this review we critically appraise the clinical features, biochemical tests, and imaging modalities used for this purpose. We outline recommendations for approaches to clinical investigation, with a particular focus on developments made within the last two years.
authors: Academic Unit of Endocrinology, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK.
authors: Eleni
authors: E
authors: Daniel
authors: John D C
authors: JD
authors: Newell-Price
mesh_terms: D049913:ACTH-Secreting Pituitary Adenoma / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D000236:Adenoma / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D000304:Adrenal Cortex Function Tests; D000324:Adrenocorticotropic Hormone / Q000097:blood; D015415:Biomarkers / Q000097:blood; D003952:Diagnostic Imaging / Q000379:methods; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D047748:Pituitary ACTH Hypersecretion / Q000097:blood / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011379:Prognosis; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone