title: Urolithiasis is associated with low serum testosterone levels in men.
abstract: OBJECTIVE
  To evaluate the relationship among urolithiasis, metabolic syndrome (MetS) and serum testosterone (T) level in men.
  
  
  METHODS
  513 men older than 18 years were enrolled in this study: 313 of the subjects had a history of stones (group 1) and 200 had no history of stones (controls, group 2). Early morning T levels were recorded and anthropometric measurements were investigated to evaluate MetS. Analyses were completed using chi-square tests.
  
  
  RESULTS
  Serum T level was lower in stone forming patients than control subjects and 161 (%51.4) men in group 1 and 92 (%46) men in group 2 were diagnosed with metabolic syndrome. T level was found lower limit (< 285 ng/dl) in the MetS and urolithiasis group (p 0.002, OR 2.71).
  
  
  CONCLUSIONS
  We found low testosterone levels in the patients with stone disease and prevalence of the MetS in men with urolithiasis was higher than in men without stone disease. Our findings show that levels of testosterone had no effect on stone formation, but the factors that cause stone formation can have an effect on the level of testosterone.
authors.affiliation: Okmeydani Training and Research Hospital, Department of Urology, Istanbul. alperotunctemur@yahoo.com.
authors.forename: Alper
authors.initials: A
authors.lastname: Otunctemur
authors.forename: Emin
authors.initials: E
authors.lastname: Ozbek
authors.forename: Suleyman Sami
authors.initials: SS
authors.lastname: Cakir
authors.forename: Murat
authors.initials: M
authors.lastname: Dursun
authors.forename: Emre Can
authors.initials: EC
authors.lastname: Polat
authors.forename: Levent
authors.initials: L
authors.lastname: Ozcan
authors.forename: Huseyin
authors.initials: H
authors.lastname: Besiroglu
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D015992:Body Mass Index; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000453:epidemiology; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D013739:Testosterone / Q000097:blood*; D014421:Turkey / Q000453:epidemiology; D052878:Urolithiasis / Q000097:blood* / Q000453:epidemiology
chemical_list: D015415:Biomarkers; D013739:Testosterone