title: Structural Characterization, Technological Functionality, and Physiological Aspects of Fungal β-D-glucans: A Review.
abstract: β-D-glucans are a (1→3)-linked glucose polymer with (1→6)-linked side chains and a major component of fungal cell walls. They exhibit structural integrity to the fungal cell wall. In addition, β-glucans are widely used as food adjuvant in food and pharmaceutical industries because of their physico-chemical properties. Several studies have focused on different isolation processes of (1→3) (1→6)-β-glucan that could affect the physico-chemical and functional properties of β-glucan such as chemical composition, solubility, viscosity, hydration properties, and oil binding capacity. Immunological activity is one of the most important properties of β-glucans. Thus, they are effective in inhibiting growth of cancer cells and metastasis and preventing bacterial infection. In humans, β-glucans reduce blood cholesterol, improve glucose absorption by body cells, and so help wound healing. This review described the prebiotic potentiality of fungal β-D-glucans with the objective to detail the methodologies applied for their extraction, their structure and techno-functional properties, and finally their biological effects.
authors.affiliation: a Unité de Science des Aliments et Formulation, Agro-Bio Tech, Université de Liège, Gembloux , Gembloux , Belgium.
authors.forename: Chema
authors.initials: C
authors.lastname: Borchani
authors.affiliation: b Unité de Bioindustries, Gembloux Agro-Bio Tech, Université de Liège , Gembloux , Belgium.
authors.forename: Fabienne
authors.initials: F
authors.lastname: Fonteyn
authors.affiliation: b Unité de Bioindustries, Gembloux Agro-Bio Tech, Université de Liège , Gembloux , Belgium.
authors.forename: Guilhem
authors.initials: G
authors.lastname: Jamin
authors.affiliation: b Unité de Bioindustries, Gembloux Agro-Bio Tech, Université de Liège , Gembloux , Belgium.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Destain
authors.affiliation: c Epigénétique Cellulaire et Moléculaire, Université de Liège , Liège , Belgium.
authors.forename: Luc
authors.initials: L
authors.lastname: Willems
authors.affiliation: d Unité de Chimie Analytique, Gembloux Agro-Bio Tech, Université de Liège , Gembloux , Belgium.
authors.forename: Michel
authors.initials: M
authors.lastname: Paquot
authors.affiliation: a Unité de Science des Aliments et Formulation, Agro-Bio Tech, Université de Liège, Gembloux , Gembloux , Belgium.
authors.forename: Christophe
authors.initials: C
authors.lastname: Blecker
authors.affiliation: b Unité de Bioindustries, Gembloux Agro-Bio Tech, Université de Liège , Gembloux , Belgium.
authors.forename: Philippe
authors.initials: P
authors.lastname: Thonart
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry; D000970:Antineoplastic Agents / Q000737:chemistry; D000975:Antioxidants / Q000032:analysis; D001794:Blood Pressure / Q000187:drug effects; D005503:Food Additives / Q000032:analysis; D005658:Fungi / Q000737:chemistry*; D006801:Humans; D007004:Hypoglycemic Agents / Q000737:chemistry; D056747:Immunomodulation; D056692:Prebiotics; D012995:Solubility; D014783:Viscosity; D014945:Wound Healing / Q000187:drug effects; D047071:beta-Glucans / Q000737:chemistry* / Q000302:isolation & purification
chemical_list: D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D000975:Antioxidants; D005503:Food Additives; D007004:Hypoglycemic Agents; D056692:Prebiotics; D047071:beta-Glucans
keywords: fungal cell wall; isolation process; prebiotic potentiality; structure; techno-functional properties; β-D-Glucans