title: The E3 ubiquitin ligase HOS1 is involved in ethylene regulation of leaf expansion in Arabidopsis.
abstract: Ethylene regulates a variety of physiological processes, such as flowering, senescence, abscission, and fruit ripening. In particular, leaf expansion is also controlled by ethylene in Arabidopsis. Exogenous treatment with ethylene inhibits leaf expansion, and consistently, ethylene insensitive mutants show increased leaf area. Here, we report that the RING finger-containing E3 ubiquitin ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1 (HOS1) regulates leaf expansion in an ethylene signaling pathway. The HOS1-deficient mutant showed reduced leaf area and was insensitive to ethylene perception inhibitor, silver thiosulfate (STS). Accordingly, genes encoding ethylene signaling components were significantly up-regulated in hos1-3. This study demonstrates that the HOS1 protein is involved in ethylene signal transduction for the proper regulation of leaf expansion possibly under environmentally stressful conditions.
authors.affiliation: a Department of Bioactive Material Sciences and Research Center of Bioactive Materials ; Chonbuk National University , Jeonju , Korea.
authors.forename: Kyounghee
authors.initials: K
authors.lastname: Lee
authors.forename: Pil Joon
authors.initials: PJ
authors.lastname: Seo
mesh_terms: D017360:Arabidopsis / Q000254:growth & development / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D005030:Ethylenes / Q000378:metabolism*; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism*; D009687:Nuclear Proteins / Q000378:metabolism*; D018515:Plant Leaves / Q000254:growth & development / Q000378:metabolism*; D054829:RING Finger Domains; D044767:Ubiquitin-Protein Ligases / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; D005030:Ethylenes; C425768:HOS1 protein, Arabidopsis; D047908:Intracellular Signaling Peptides and Proteins; D009687:Nuclear Proteins; C036216:ethylene; D044767:Ubiquitin-Protein Ligases
keywords: Arabidopsis; CTR1, CONSTITUTIVE TRIPLE RESPONSE 1; EIN, ETHYLENE INSENSITIVE; ERF, ETHYLENE-RESPONSE FACTOR; ERS, ETHYLENE RESPONSE SENSOR; ESE1, ETHYLENE AND SALT INDUCIBLE 1; ETR, ETHYLENE RECEPTOR; HOS1; HOS1, HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1; STS, silver thiosulfate; ethylene; leaf expansion
references.citation: Plant Cell. 2007 Jul;19(7):2169-85
references.pmid: 17630276
references.citation: J Biol Chem. 2012 Jul 27;287(31):26094-103
references.pmid: 22692214
references.citation: Plant J. 1998 Nov;16(4):433-42
references.pmid: 9881163
references.citation: Genes Dev. 2003 Apr 15;17(8):1043-54
references.pmid: 12672693
references.citation: Plant Cell. 2007 Jul;19(7):2186-96
references.pmid: 17630275
references.citation: Plant J. 1997 Nov;12(5):1163-72
references.pmid: 9418054
references.citation: Science. 1999 Feb 12;283(5404):996-8
references.pmid: 9974395
references.citation: J Exp Bot. 2005 Nov;56(421):2915-23
references.pmid: 16172137
references.citation: Science. 1995 Sep 22;269(5231):1712-4
references.pmid: 7569898
references.citation: Plant Cell Environ. 2010 Jul;33(7):1124-37
references.pmid: 20199622
references.citation: Plant Physiol. 2004 Mar;134(3):1217-26
references.pmid: 14988474
references.citation: Plant Cell. 2012 Mar;24(3):982-99
references.pmid: 22408073
references.citation: Can J Bot. 1997 Mar;75(3):501-8
references.pmid: 11541081
references.citation: Plant Cell. 2003 Oct;15(10):2296-307
references.pmid: 12972671
references.citation: Trends Plant Sci. 2012 Jun;17(6):332-40
references.pmid: 22401845
references.citation: Plant Cell. 1998 Jul;10(7):1151-61
references.pmid: 9668134
references.citation: Plant Physiol. 2002 Dec;130(4):1908-17
references.pmid: 12481073
references.citation: Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2756-61
references.pmid: 11038610
references.citation: New Phytol. 2013 Jan;197(2):490-502
references.pmid: 23253334
references.citation: Genes Dev. 2001 Apr 1;15(7):912-24
references.pmid: 11297514
references.citation: Plant J. 2007 Aug;51(3):458-67
references.pmid: 17655616
references.citation: Proc Natl Acad Sci U S A. 2006 May 23;103(21):8281-6
references.pmid: 16702557
references.citation: Cell. 1997 Jun 27;89(7):1133-44
references.pmid: 9215635
references.citation: Plant J. 2006 Mar;45(5):804-18
references.pmid: 16460513
references.citation: J Integr Plant Biol. 2008 Jul;50(7):808-15
references.pmid: 18713391
references.citation: J Exp Bot. 2002 Mar;53(368):489-503
references.pmid: 11847248
references.citation: Plant Cell Physiol. 2001 Jun;42(6):608-19
references.pmid: 11427680
references.citation: Curr Opin Plant Biol. 1999 Oct;2(5):352-8
references.pmid: 10508761
references.citation: Plant Cell. 2010 Jul;22(7):2384-401
references.pmid: 20647342
references.citation: Curr Opin Plant Biol. 2004 Feb;7(1):40-9
references.pmid: 14732440
references.citation: Front Plant Sci. 2014 Jul 31;5:362
references.pmid: 25132838
references.citation: Plant Cell. 2009 Dec;21(12):3803-22
references.pmid: 20023197
references.citation: Cell. 1993 Feb 12;72(3):427-41
references.pmid: 8431946
references.citation: Plant Physiol. 2004 Apr;134(4):1803-12
references.pmid: 15064382