title: The Autism Diagnostic Observation Schedule, Toddler Module: Standardized Severity Scores.
abstract: Standardized calibrated severity scores (CSS) have been created for Autism Diagnostic Observation Schedule, 2nd edition (ADOS-2) Modules 1-4 as a metric of the relative severity of autism-specific behaviors. Total and domain CSS were created for the Toddler Module to facilitate comparison to other modules. Analyses included 388 children with ASD age 12-30 months and were replicated on 435 repeated assessments from 127 children with ASD. Compared to raw scores, associations between total and domain CSS and participant characteristics were reduced in the original sample. Verbal IQ effects on Social Affect-CSS were not reduced in the replication sample. Toddler Module CSS increases comparability of ADOS-2 scores across modules and allows studies of symptom trajectories to extend to earlier ages.
authors.affiliation: Department of Pediatrics, University of Minnesota, 717 Delaware St SE, Minneapolis, MN, 55414, USA, esle0007@umn.edu.
authors.forename: Amy N
authors.initials: AN
authors.lastname: Esler
authors.forename: Vanessa Hus
authors.initials: VH
authors.lastname: Bal
authors.forename: Whitney
authors.initials: W
authors.lastname: Guthrie
authors.forename: Amy
authors.initials: A
authors.lastname: Wetherby
authors.forename: Susan
authors.initials: S
authors.lastname: Ellis Weismer
authors.forename: Catherine
authors.initials: C
authors.lastname: Lord
mesh_terms: D001321:Autistic Disorder / Q000175:diagnosis*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D011581:Psychological Tests / Q000592:standards*
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