title: Development of Methods for Determination of Aflatoxins.
abstract: Aflatoxins can cause damage to the health of humans and animals. Several institutions around the world have established regulations to limit the levels of aflatoxins in food, and numerous analytical methods have been extensively developed for aflatoxin determination. This review covers the currently used analytical methods for the determination of aflatoxins in different food matrices, which includes sampling and sample preparation, sample pretreatment methods including extraction methods and purification methods of aflatoxin extracts, separation and determination methods. Validation for analysis of aflatoxins and safety considerations and precautions when doing the experiments are also discussed.
authors.affiliation: a College of Biosystems Engineering and Food Science , Zhejiang University , Hangzhou , P. R. China.|b Key Laboratory of Equipment and Informatization in Environment Controlled Agriculture , Ministry of Agriculture , Hangzhou , P. R. China.
authors.forename: Lijuan
authors.initials: L
authors.lastname: Xie
authors.affiliation: a College of Biosystems Engineering and Food Science , Zhejiang University , Hangzhou , P. R. China.|b Key Laboratory of Equipment and Informatization in Environment Controlled Agriculture , Ministry of Agriculture , Hangzhou , P. R. China.
authors.forename: Min
authors.initials: M
authors.lastname: Chen
authors.affiliation: a College of Biosystems Engineering and Food Science , Zhejiang University , Hangzhou , P. R. China.|b Key Laboratory of Equipment and Informatization in Environment Controlled Agriculture , Ministry of Agriculture , Hangzhou , P. R. China.
authors.forename: Yibin
authors.initials: Y
authors.lastname: Ying
mesh_terms: D000348:Aflatoxins / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D004797:Enzyme-Linked Immunosorbent Assay; D005504:Food Analysis / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D005516:Food Microbiology; D057230:Limit of Detection; D015203:Reproducibility of Results; D053719:Tandem Mass Spectrometry; D014465:Ultrasonics
chemical_list: D000348:Aflatoxins
keywords: Aflatoxin; determination; method; sample preparation; sample pretreatment; separation