title: The role of negative pressure wound therapy in patients with kidney transplantation.
abstract: Kidney transplantation is the best treatment modality for patients with end-stage renal disease. Wound healing is impaired in these patients, and factors such as immunosuppression, older age and comorbidities have a negative impact on wound healing. Recently, negative pressure wound therapy has become an important wound management technique. We present two patients with wound healing issues in the early posttransplant period. In both patients, an imrnunosup- pressive treatment was administered, which included tacrolimus, mycophenolate mophetil and high-dose corticosteroids with anti-IL-2 induction therapy. Postoperatively, the wounds became inflamed with dehiscence. Negative pressure wound therapy was successfully applied to aid the wound healing. The treatment duration period was two weeks for one patient and three weeks for the other. After the treatment period, the wounds were significantly improved and were closed. After the secondary wound closures, the posttransplant course was uneventful in both patients. Presently, one and three years after the transplantations, both patients have well functioning kidneys. According to our limited experience, negative pressure wound therapy is a feasible and effective dehiscence wound treatment following kidney transplantation.
authors.forename: Dean
authors.initials: D
authors.lastname: Markić
authors.forename: Marin
authors.initials: M
authors.lastname: Marinović
authors.forename: Stanislav
authors.initials: S
authors.lastname: Sotosek
authors.forename: Josip
authors.initials: J
authors.lastname: Spanjol
authors.forename: Aldo
authors.initials: A
authors.lastname: Ivancić
authors.forename: Maricić
authors.initials: M
authors.lastname: Anton
authors.forename: Zeljko
authors.initials: Z
authors.lastname: Fuckar
mesh_terms: D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy; D016896:Treatment Outcome; D014947:Wounds and Injuries / Q000628:therapy*