title: The effect of admission at weekends on clinical outcomes in patients with non-ST-segment elevation acute coronary syndrome and its contributing factors.
abstract: We investigated the effects of weekend admission on adverse cardiac events in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). Patients with NSTE-ACS treated with percutaneous coronary intervention (PCI) were divided into a "weekend group" and a "weekday group" according to the emergency room arrival time. The primary outcome was 30-day major adverse cardiac events (MACE) including cardiac death, recurrent myocardial infarction, repeat revascularization, and urgent PCI. Of 577 patients, 168 patients were allocated to the weekend and 409 patients to the weekday group. The incidence of 30-day MACE was significantly higher in the weekend group (Crude: 15.5% vs. 7.3%, P = 0.005; propensity score matched: 12.8% vs. 4.8%, P = 0.041). After adjustment for all the possible confounding factors, in Cox proportional hazard regression analysis, weekend admission was associated with a 2.1-fold increased hazard for MACE (HR, 2.13; 95% CI, 1.26-3.60, P = 0.005). These findings indicate that weekend admission of patients with NSTE-ACS is associated with an increase in 30-day adverse cardiac event.
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
authors.forename: Hyun-Jin
authors.identifier: 0000-0002-7885-1695
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Kwang-Il
authors.identifier: 0000-0002-6658-047X
authors.initials: KI
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Young-Seok
authors.identifier: 0000-0001-9944-9868
authors.initials: YS
authors.lastname: Cho
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
authors.forename: Jeehoon
authors.identifier: 0000-0002-9078-2231
authors.initials: J
authors.lastname: Kang
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Jin Joo
authors.identifier: 0000-0001-9611-1490
authors.initials: JJ
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Il-Young
authors.identifier: 0000-0002-5584-605X
authors.initials: IY
authors.lastname: Oh
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Chang-Hwan
authors.identifier: 0000-0001-6305-4442
authors.initials: CH
authors.lastname: Yoon
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Jung-Won
authors.identifier: 0000-0002-0397-6071
authors.initials: JW
authors.lastname: Suh
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Tae-Jin
authors.identifier: 0000-0002-4628-9503
authors.initials: TJ
authors.lastname: Youn
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: In-Ho
authors.identifier: 0000-0003-1644-2105
authors.initials: IH
authors.lastname: Chae
authors.affiliation: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors.forename: Dong-Ju
authors.identifier: 0000-0003-0146-2189
authors.initials: DJ
authors.lastname: Choi
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications* / Q000401:mortality / Q000628:therapy; D000328:Adult; D000368:Aged; D003643:Death; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology*; D010343:Patient Admission; D062645:Percutaneous Coronary Intervention / Q000706:statistics & numerical data*; D057216:Propensity Score; D016016:Proportional Hazards Models; D013997:Time Factors; D016896:Treatment Outcome
keywords: Acute Coronary Syndrome; Coronary Artery Disease; Percutaneous Coronary Intervention
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