title: Leishmaniasis, malaria, and schistosomiasis concurrently in an 8-year-old boy.
abstract: An overlap in the distribution of the 2 diseases (leishmaniasis and malaria) was reported in endemic areas, and it can cause significant delay in the diagnosis of leishmaniasis. Here, an 8-year-old Yemeni boy who was initially diagnosed as malaria and schistosomiasis, and later on as leishmaniasis is reported. He presented with prolonged fever, hepatosplenomegaly, and diarrhea. His blood film was positive for Plasmodium falciparum malaria, and his stool was positive for Schistosoma mansoni. Although a full therapeutic course of antimalarial and schistosoma was administered, his fever, weight loss, and increased hepatosplenomegaly continued. Bone marrow aspiration was carried out revealing Leishman-Donovan bodies (amastigote form). He was successfully treated with a full course of sodium stibogluconate. This case stresses the importance of alertness among the treating physicians to this disease occurring in a patient from an endemic area, presenting with prolonged fever, and hepatosplenomegaly.
authors.affiliation: Department of Pediatrics, Faculty of Medicine and Health Sciences, Sana'a University, Sana'a, Yemen. Tel. +97 (77) 7907420. E-mail. mabrookmohanna@yahoo.com.
authors.forename: Mabrook A
authors.initials: MA
authors.lastname: Bin Mohanna
mesh_terms: D002648:Child; D005334:Fever / Q000209:etiology; D006529:Hepatomegaly / Q000209:etiology; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008288:Malaria / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D012552:Schistosomiasis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
references.citation: Mol Biol Int. 2011;2011:571242
references.pmid: 22091408
references.citation: J Microbiol Immunol Infect. 2011 Feb;44(1):72-6
references.pmid: 21531357
references.citation: Rev Inst Med Trop Sao Paulo. 2014 Jan-Feb;56(1):81-4
references.pmid: 24553614
references.citation: PLoS Negl Trop Dis. 2013;7(8):e2377
references.pmid: 23991235
references.citation: Indian J Med Res. 2013 Apr;137(4):767-76
references.pmid: 23703346
references.citation: PLoS Negl Trop Dis. 2012;6(2):e1475
references.pmid: 22389729
references.citation: Parasit Vectors. 2014;7:351
references.pmid: 25074325
references.citation: Clin Diagn Lab Immunol. 2002 Sep;9(5):951-8
references.pmid: 12204943
references.citation: Indian J Nephrol. 2012 Jul;22(4):301-3
references.pmid: 23162277