title: Thoracic Spondylodiscitis Caused by Methicillin-resistant Staphylococcus aureus as a Superinfection of Pulmonary Tuberculous Granuloma in an Immunocompetent Patient: A Case Report.
abstract: Study Design Case report. Objective To describe a very rare case of an immunocompetent man who underwent surgery for thoracic spondylodiscitis caused by methicillin-resistant Staphylococcus aureus (MRSA) that developed as a superinfection of a pulmonary tuberculous granuloma. Methods Posterior decompression and pedicle screw vertebral fixation were followed by T5-T6 anterior somatotomy with implant of an expandable mesh and lateral plating as symptoms worsened. During the anterior approach, an atypical resection of the left lower lobe was also performed. Results A tuberculous granuloma was detected on histology. Ziehl-Neelsen stain confirmed the diagnosis. Culture also detected MRSA. Conclusions Early medical management is the first choice for spondylodiscitis to eradicate the infection and alleviate pain. Immobilization of the affected spine segments can protect the patient from vertebral collapse and from the appearance of neurologic deficits. Surgery is suggested if there are compressive effects on the spinal cord, spinal epidural abscess, vertebral collapse, and deformity. We decided to remove the abscess and to restore the anterior column using an anterior approach. Moreover, in this case, an anterior approach allowed us to identify the etiology of the lesion and to determine the best chemotherapy regimen.
authors.affiliation: Department of Neurosurgery, "Sapienza" University, Rome, Italy.
authors.forename: Pasquale
authors.initials: P
authors.lastname: Donnarumma
authors.affiliation: Department of Neurosurgery, "Sapienza" University, Rome, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Tarantino
authors.affiliation: Department of Neurosurgery, "Sapienza" University, Rome, Italy.
authors.forename: Valeria
authors.initials: V
authors.lastname: Palmarini
authors.affiliation: Department of Thoracic Surgery, "Sapienza" University, Rome, Italy.
authors.forename: Tiziano
authors.initials: T
authors.lastname: De Giacomo
authors.affiliation: Department of Neurosurgery, "Sapienza" University, Rome, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Delfini
keywords: methicillin-resistant Staphylococcus aureus (MRSA); pulmonary tuberculous granuloma; spondylodiscitis; thoracotomy
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