title: Laboratory Studies of Aedes aegypti Attraction to Ketones, Sulfides, and Primary Chloroalkanes Tested Alone and in Combination with L-Lactic Acid.
abstract: The attraction of female Aedes aegypti to single compounds and binary compositions containing L-lactic acid and an additional saturated compound from a set of ketones, sulfides, and chloroalkanes was studied using a triple-cage dual-port olfactometer. These chemical classes were studied because of their structural relation to acetone, dimethyl disulfide, and dichloromethane, which have all been reported to synergize attraction to L-lactic acid. Human odors, carbon dioxide, and the binary mixture of L-lactic acid and CO₂served as controls for comparison of attraction responses produced by the binary mixtures. All tested mixtures that contained chloroalkanes attracted mosquitoes at synergistic levels, as did L-lactic acid and CO₂. Synergism was less frequent in mixtures of L-lactic acid with sulfides and ketones; in the case of ketones, synergistic attraction was observed only for L-lactic acid combined with acetone or butanone. Suppression or inhibition of attraction response was observed for combinations that contained ketones of C7-C12 molecular chain length (optimum in the C8-C10 range). This inhibition effect is similar to that observed previously for specific ranges of carboxylic acids, aldehydes, and alcohols.
authors.affiliation: United States Department of Agriculture-Agricultural Research Service, Center for Medical, Agricultural, and Veterinary Entomology, 1600 SW 23rd Drive, Gainesville, FL 32608.
authors.forename: Ulrich R
authors.initials: UR
authors.lastname: Bernier
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Kline
authors.forename: Sandra A
authors.initials: SA
authors.lastname: Allan
authors.forename: Donald R
authors.initials: DR
authors.lastname: Barnard
mesh_terms: D000330:Aedes / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D002633:Chemotaxis / Q000187:drug effects*; D005260:Female; D006843:Hydrocarbons, Chlorinated / Q000494:pharmacology; D007659:Ketones / Q000494:pharmacology; D019344:Lactic Acid / Q000494:pharmacology*; D064367:Olfactometry; D010675:Pheromones / Q000494:pharmacology*; D013440:Sulfides / Q000494:pharmacology
chemical_list: D006843:Hydrocarbons, Chlorinated; D007659:Ketones; D010675:Pheromones; D013440:Sulfides; C010411:insect attractants; D019344:Lactic Acid
keywords: blends; lures; mosquito attractments; olfactometer