title: Preference for concentric orientations in the mouse superior colliculus.
abstract: The superior colliculus is a layered structure important for body- and gaze-orienting responses. Its superficial layer is, next to the lateral geniculate nucleus, the second major target of retinal ganglion axons and is retinotopically organized. Here we show that in the mouse there is also a precise organization of orientation preference. In columns perpendicular to the tectal surface, neurons respond to the same visual location and prefer gratings of the same orientation. Calcium imaging and extracellular recording revealed that the preferred grating varies with retinotopic location, and is oriented parallel to the concentric circle around the centre of vision through the receptive field. This implies that not all orientations are equally represented across the visual field. This makes the superior colliculus different from visual cortex and unsuitable for translation-invariant object recognition and suggests that visual stimuli might have different behavioural consequences depending on their retinotopic location.
authors.affiliation: Netherlands Institute for Neuroscience, an institute of the Royal Academy of Arts and Sciences, Cortical Structure &Function group, Meibergdreef 47, 1105 BA Amsterdam, The Netherlands.
authors.forename: Mehran
authors.initials: M
authors.lastname: Ahmadlou
authors.affiliation: Netherlands Institute for Neuroscience, an institute of the Royal Academy of Arts and Sciences, Cortical Structure &Function group, Meibergdreef 47, 1105 BA Amsterdam, The Netherlands.
authors.forename: J Alexander
authors.initials: JA
authors.lastname: Heimel
mesh_terms: D000818:Animals; D004567:Electrodes, Implanted; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D010364:Pattern Recognition, Visual; D010775:Photic Stimulation; D012160:Retina / Q000502:physiology*; D012165:Retinal Ganglion Cells / Q000502:physiology*; D013477:Superior Colliculi / Q000033:anatomy & histology / Q000502:physiology*; D014793:Visual Cortex; D014795:Visual Pathways / Q000033:anatomy & histology / Q000502:physiology*; D014796:Visual Perception
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