title: Management of immune thrombocytopenia in adults: a population-based analysis of the French hospital discharge database from 2009 to 2012.
abstract: The present study describes the current clinical practice and hospital management of adults with immune thrombocytopenia (ITP) between 2009 and 2012 in France, based on the national discharge hospital database. Adult ITP patients were managed almost exclusively in public hospitals. A relatively stable number of patients, around 3200 per year, were hospitalized for ITP annually over the 4-year period, about two-thirds of whom were newly-diagnosed ITP. Re-hospitalizations tended to decrease over the study period. Intravenous immunoglobulin administration, concerning half of ITP hospitalized patients, and rituximab administration were stable over time, whereas a slight decrease of splenectomies was observed.
authors.affiliation: Department of Internal Medicine, National Reference Centre for Autoimmune Cytopenia in Adults, Henri-Mondor University Hospital, Asssitance Publique Hôpitaux de Paris, Université Paris-Est Créteil (UPEC), Créteil, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Michel
authors.affiliation: Amgen S.A.S., Neuilly-sur-Seine, France.
authors.forename: Florence
authors.initials: F
authors.lastname: Suzan
authors.affiliation: Department of Internal Medicine, University Hospital, Toulouse, France.
authors.forename: Daniel
authors.initials: D
authors.lastname: Adoue
authors.affiliation: Department of Haematology, University Hospital, Limoges, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Bordessoule
authors.affiliation: Department of Haematology, University Hospital, Amiens, France.
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Marolleau
authors.affiliation: Department of Internal Medicine, University Hospital, Pessac, France.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Viallard
authors.affiliation: Department of Internal Medicine, National Reference Centre for Autoimmune Cytopenia in Adults, Henri-Mondor University Hospital, Asssitance Publique Hôpitaux de Paris, Université Paris-Est Créteil (UPEC), Créteil, France.
authors.forename: Bertrand
authors.initials: B
authors.lastname: Godeau
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D058846:Antibodies, Monoclonal, Murine-Derived / Q000627:therapeutic use; D016208:Databases, Factual; D019468:Disease Management; D005260:Female; D005602:France / Q000453:epidemiology; D006470:Hemorrhage / Q000209:etiology; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D011379:Prognosis; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications / Q000453:epidemiology* / Q000628:therapy; D012189:Retrospective Studies; D000069283:Rituximab; D013156:Splenectomy; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D016756:Immunoglobulins, Intravenous; D000069283:Rituximab
keywords: health services research; immune thrombocytopenia; immunoglobulin; splenectomy