title: Effects of Resistance versus Endurance Training on Plasma Lipocalin-2 in Young Men.
abstract: OBJECTIVE
  Lipocalin-2 (Lcn2) has been recognized as an adipocyte-derived acute phase protein that is positively correlated with obesity, insulin resistance, type 2 diabetes, and cardiovascular disease. The effects of resistance and endurance training (RT vs. ET) on plasma lipocalin-2 are still unclear. Therefore, the purpose of this study was to examine the effects of RT vs. ET on plasma lipocalin-2 in young men.
  
  
  METHODS
  Twenty nine healthy and sedentary young men (age, 21-29 years) participated in this study. The subjects were randomly assigned to RT group (n=9), ET group (n=10) or control group (n=10). The experimental groups performed either RT or ET, 3 days a week for 8 weeks. The endurance training program included continuous running at an intensity corresponding to 65-80% of maximal heart rate, while resistance training consisted of 2-4 sets of circuit weight training for 8 stations and at an intensity corresponding to 65-80% of 1-RM in each station.
  
  
  RESULTS
  No significant changes in the body mass, BMI, body fat percentage and WHR were found after the RT and ET. The results showed that Lcn2 decreased after RT and ET compared with the control group (P<0.05). High sensitivity C-reactive protein (hs-CRP) and insulin resistance determined by HOMA-IR, did not change in the RT and ET compared with the control group.
  
  
  CONCLUSIONS
  Lcn2 decreases after 8 weeks RT and ET, but this improvement was not accompanied by decreased hs-CRP and insulin resistance in healthy and sedentary young men.
authors.affiliation: Department of Exercise Physiology, Shiraz branch, Islamic Azad University, Shiraz, Iran.
authors.forename: Mehrzad
authors.initials: M
authors.lastname: Moghadasi
authors.affiliation: Department of Exercise Physiology, Gachsaran branch, Islamic Azad University, Gachsaran, Iran.
authors.forename: Amin
authors.initials: A
authors.lastname: Mohammadi Domieh
keywords: Exercise; Insulin Resistance; Lipocalin-2 Protein, Human; Resistance Training
references.citation: Eur J Endocrinol. 2008 Feb;158(2):203-7
references.pmid: 18230827
references.citation: N Engl J Med. 2002 Nov 7;347(19):1522-4
references.pmid: 12421896
references.citation: Clin Chem. 2007 Jan;53(1):5-7
references.pmid: 17202496
references.citation: J Clin Invest. 2005 May;115(5):1111-9
references.pmid: 15864338
references.citation: Diabetes. 2005 Apr;54(4):917-27
references.pmid: 15793228
references.citation: Oncogene. 1989 May;4(5):601-8
references.pmid: 2542864
references.citation: Asian J Sports Med. 2011 Mar;2(1):44-50
references.pmid: 22375217
references.citation: Clin Chem. 2007 Jan;53(1):34-41
references.pmid: 17040956
references.citation: J Appl Physiol (1985). 2005 Apr;98(4):1154-62
references.pmid: 15772055
references.citation: J Clin Invest. 2003 Dec;112(12):1796-808
references.pmid: 14679176
references.citation: J Allergy Clin Immunol. 2005 May;115(5):911-9; quiz 920
references.pmid: 15867843
references.citation: J Appl Physiol (1985). 1999 Sep;87(3):982-92
references.pmid: 10484567
references.citation: Clin Exp Dermatol. 2012 Apr;37(3):296-9
references.pmid: 22300286
references.citation: Circ Res. 2005 May 13;96(9):939-49
references.pmid: 15890981
references.citation: J Cell Biochem. 2009 Jan 1;106(1):103-8
references.pmid: 19009554
references.citation: Diabetes. 2007 Oct;56(10 ):2533-40
references.pmid: 17639021
references.citation: Med Sci Sports Exerc. 2003 Jun;35(6):1026-32
references.pmid: 12783052
references.citation: Clin Endocrinol (Oxf). 2009 Apr;70(4):569-74
references.pmid: 18710473
references.citation: Endocr J. 2003 Apr;50(2):233-8
references.pmid: 12803245
references.citation: Nutrition. 2004 Mar;20(3):323-6
references.pmid: 14990277
references.citation: Diabetologia. 1985 Jul;28(7):412-9
references.pmid: 3899825