title: Role of dual time fluorodeoxyglucose (FDG) positron emission tomography-computed tomography in identifying co-existing inflammatory and malignant disease: Who holds it (FDG) longer?
abstract: 18-fluorodeoxyglucose positron emission tomography-computed tomography (PET-CT) is an integral part of imaging in the follow-up of head and neck malignancies. Very often distinguishing inflammatory/infective from malignant recurrence cannot be made confidently with standard uptake value (SUV) alone, as inflammatory lesions have shown to have a very high SUV, and in some cases both can co-exist. In such doubtful cases, dual time PET-CT (3-5 h delayed) is of paramount importance in confidently differentiating inflammatory/infective from a malignant cause.
authors.affiliation: Department of Radiodiagnosis, Kerala Institute of Medical Science, Trivandrum, Kerala, India.
authors.forename: Anirudh V
authors.initials: AV
authors.lastname: Nair
authors.affiliation: Department of Radiodiagnosis, Amrita Institute of Medical Science, Kochi, Kerala, India.
authors.forename: C J
authors.initials: CJ
authors.lastname: Sandya
authors.affiliation: Department of Nuclear Medicine, Amrita Institute of Medical Science, Kochi, Kerala, India.
authors.forename: G S
authors.initials: GS
authors.lastname: Shagos
authors.affiliation: Department of Pathology, Trivandrum Medical College, Trivandrum, Kerala, India.
authors.forename: Soumya
authors.initials: S
authors.lastname: Anirudh
authors.affiliation: Department of Pathology, Amrita Institute of Medical Science, Kochi, Kerala, India.
authors.forename: Bindhu Mangalath
authors.initials: BM
authors.lastname: Rajamma
authors.affiliation: Department of Radiodiagnosis, Amrita Institute of Medical Science, Kochi, Kerala, India.
authors.forename: P V
authors.initials: PV
authors.lastname: Ramachandran
authors.affiliation: Department of Radiodiagnosis, Amrita Institute of Medical Science, Kochi, Kerala, India.
authors.forename: Srikanth
authors.initials: S
authors.lastname: Moorthy
keywords: Dual time positron emission tomography-computed tomography; head and neck; inflammatory malignant; squamous cell carcinoma
references.citation: J Nucl Med. 1995 Jul;36(7):1301-6
references.pmid: 7790960
references.citation: J Clin Oncol. 2002 Oct 15;20(20):4199-208
references.pmid: 12377963
references.citation: Eur J Nucl Med. 1998 Sep;25(9):1238-43
references.pmid: 9724371
references.citation: Arch Biochem Biophys. 1984 Dec;235(2):418-26
references.pmid: 6097186
references.citation: Nucl Med Biol. 1996 May;23(4):533-41
references.pmid: 8832712
references.citation: Eur J Nucl Med. 1999 Mar;26(3):226-30
references.pmid: 10079312
references.citation: Cancer Res. 1996 Mar 1;56(5):1164-7
references.pmid: 8640778
references.citation: J Nucl Med. 2001 Sep;42(9):1412-7
references.pmid: 11535734