title: Effect of the coating material on root dentin remineralization in vitro.
abstract: OBJECTIVE
  A fluoride-releasing coating material containing surface pre-reacted glass-ionomer (S-PRG) filler has become commercially available. However, there has been no detailed investigation of its remineralization effects at various tooth surface regions. The remineralization effects of S-PRG filler-containing coating material at different sites of demineralized dentin surfaces in vitro were evaluated.
  
  
  METHODS
  Baseline lesions were prepared on bovine root dentin surfaces by immersion in demineralization buffer and divided into four groups: (B)--baseline lesion; (P)--S-PRG filler-containing material; (V)--S-PRG filler-free coating material as negative control; and (X)--resin-modified glass- ionomer as positive control. Material was applied to half the lesion surface, then P, V and X were remineralized in a gel system. Mineral profiles, integrated mineral loss (IML) and lesion depth (LD) at four regions, i.e. 1--exposed dentin surface adjacent to the material; 2--at a distance from the material; 3--beneath the material near to the edge; and 4--at a distance from the edge, were analyzed by transversal microradiography. Data were analyzed using ANOVA and Games-Howell test with α = 0.05.
  
  
  RESULTS
  B showed typical artificial demineralized lesion. The IMLs of V, P and X at regions 1 and 2, and P and X at region 3 were significantly lower than that of B, however, those of V at region 3 and the other three groups at region 4 were not significantly different from that of B. At region 1, P and X showed significantly lower IMLs than V. At region 2, the IML of X showed significantly lower IML than V. There was no significant difference between P and X. The LD values of V, P and X at all regions were not significantly different from that of B. Fluoride, strontium and silicate ions released from the S-PRG filler would provide a favorable environment for remineralization of the demineralized dentin in P.
authors.forename: Toru
authors.initials: T
authors.lastname: Shiiya
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Tomiyama
authors.forename: Junko
authors.initials: J
authors.lastname: Iizuka
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Hasegawa
authors.forename: Erika
authors.initials: E
authors.lastname: Kuramochi
authors.forename: Fukue
authors.initials: F
authors.lastname: Fujino
authors.forename: Katsura
authors.initials: K
authors.lastname: Ohashi
authors.forename: Tomotaro
authors.initials: T
authors.lastname: Nihei
authors.forename: Toshio
authors.initials: T
authors.lastname: Teranaka
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Mukai
mesh_terms: D000818:Animals; D002417:Cattle; D020099:Coated Materials, Biocompatible; D003804:Dentin / Q000187:drug effects*; D014089:Tooth Remineralization; D014092:Tooth Root / Q000503:physiopathology*
chemical_list: D020099:Coated Materials, Biocompatible