title: Interferometric Detection of Single Gold Nanoparticles Calibrated against TEM Size Distributions.
abstract: Single nanoparticle analysis: An interferometric optical approach calibrates sizes of gold nanoparticles (AuNPs) from the interference intensities by calibrating their interferometric signals against the corresponding transmission electron microscopy measurements. This method is used to investigate whether size affects the diffusion behavior of AuNPs conjugated to supported lipid bilayer membranes and to multiplex the simultaneous detection of three different AuNP labels.
authors.affiliation: Bio-Nanotechnology Laboratory, Department of Chemistry Nano-Science Center, Lundbeck Foundation Center Biomembranes in Nanomedicine, University of Copenhagen, 2100, Copenhagen, Denmark.
authors.forename: Lixue
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Bio-Nanotechnology Laboratory, Department of Chemistry Nano-Science Center, Lundbeck Foundation Center Biomembranes in Nanomedicine, University of Copenhagen, 2100, Copenhagen, Denmark.
authors.forename: Sune M
authors.initials: SM
authors.lastname: Christensen
authors.affiliation: Bio-Nanotechnology Laboratory, Department of Chemistry Nano-Science Center, Lundbeck Foundation Center Biomembranes in Nanomedicine, University of Copenhagen, 2100, Copenhagen, Denmark.
authors.forename: Poul Martin
authors.initials: PM
authors.lastname: Bendix
authors.affiliation: Bio-Nanotechnology Laboratory, Department of Chemistry Nano-Science Center, Lundbeck Foundation Center Biomembranes in Nanomedicine, University of Copenhagen, 2100, Copenhagen, Denmark.
authors.forename: Vikram Kjøller
authors.initials: VK
authors.lastname: Bhatia
authors.affiliation: Institute of Public Health Department of Environmental Health, University of Copenhagen, 2100, Copenhagen, Denmark.
authors.forename: Steffen
authors.initials: S
authors.lastname: Loft
authors.affiliation: Bio-Nanotechnology Laboratory, Department of Chemistry Nano-Science Center, Lundbeck Foundation Center Biomembranes in Nanomedicine, University of Copenhagen, 2100, Copenhagen, Denmark.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Stamou
mesh_terms: D002138:Calibration / Q000592:standards; D006046:Gold / Q000032:analysis* / Q000737:chemistry; D007368:Interferometry / Q000592:standards*; D008051:Lipid Bilayers / Q000737:chemistry*; D008422:Materials Testing / Q000592:standards*; D053768:Metal Nanoparticles / Q000032:analysis*; D046529:Microscopy, Electron, Transmission / Q000592:standards*; D010316:Particle Size; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D008051:Lipid Bilayers; D006046:Gold
keywords: diffusion coefficients; gold nanoparticles; interferometric optics; lipid bilayers; membranes; size determination