title: Anti-Müllerian Hormone in Peritoneal Fluid and Plasma From Women With and Without Endometriosis.
abstract: Anti-Müllerian hormone (AMH) has potential local effects on ovarian function and endometrial tissue, including endometriosis, but its presence in peritoneal fluid is not fully understood. This is a cross-sectional study evaluating AMH in peritoneal fluid and plasma from women with endometriosis (N = 61) and from control women without endometriosis (N = 36). There was a significant correlation between AMH in plasma and peritoneal fluid from both patients with endometriosis (r(2) = .767 [P < .001]) and control participants (r(2) = .647 [P < .001]) less than 45 years of age. Anti-Müllerian hormone declined with women's increasing age in both plasma and peritoneal fluid in women with and without endometriosis. There were no differences in the plasma or peritoneal fluid AMH in women with endometriosis versus control women. The strong relationship between plasma and peritoneal fluid may allow plasma AMH to be a marker for peritoneal AMH in studies evaluating the local effects of AMH.
authors.affiliation: Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA hhipp@emory.edu.
authors.forename: Heather
authors.initials: H
authors.lastname: Hipp
authors.affiliation: Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Tammy L
authors.initials: TL
authors.lastname: Loucks
authors.affiliation: Nezhat Medical Center, Atlanta, GA, USA.
authors.forename: Ceana
authors.initials: C
authors.lastname: Nezhat
authors.affiliation: Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Neil
authors.initials: N
authors.lastname: Sidell
authors.affiliation: Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Donna R
authors.initials: DR
authors.lastname: Session
mesh_terms: D000328:Adult; D000367:Age Factors; D054304:Anti-Mullerian Hormone / Q000097:blood*; D001202:Ascitic Fluid / Q000737:chemistry*; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D015536:Down-Regulation; D004715:Endometriosis / Q000097:blood* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008875:Middle Aged
chemical_list: D015415:Biomarkers; D054304:Anti-Mullerian Hormone
keywords: anti-Müllerian hormone; endometriosis; peritoneal fluid