title: [Structure, function, and biosynthesis of thiazoleoxazole modified microcins].
abstract: Recent advances in a large-scale genome sequencing and data analysis led to discovery of a large number of diverse ribosomally-synthesized posttranslationally-modified natural products. One bourgeoning family of such compounds, characterized by the presence of thiazole and oxazoleheterocycles derived from cysteine and serine residues, is referred to as thiazoleoxazole modified microcins. This review brings together known information about classification, structure, and biosynthesis of thiazole-oxazole modified microcins, their biological activity and potential applications.
authors.forename: M V
authors.initials: MV
authors.lastname: Meterev
authors.forename: D A
authors.initials: DA
authors.lastname: Giliarov
mesh_terms: D001430:Bacteriocins / Q000096:biosynthesis* / Q000145:classification* / Q000235:genetics; D010080:Oxazoles / Q000378:metabolism*; D011499:Protein Processing, Post-Translational / Q000502:physiology*; D017433:Protein Structure, Secondary; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000378:metabolism*
chemical_list: D001430:Bacteriocins; D010080:Oxazoles; D013844:Thiazoles; C020411:microcin