title: [Copeptin and ischemia modified albumin in early diagnosis and prognosis of myocardial damage in acute organic phosphorus pesticide poisoning].
abstract: OBJECTIVE
  To assess the value of combined detection of copeptin and ischemia modified albumin (IMA) in early diagnosis and prognostic evaluation of myocardial damage in patients with acute organic phosphorus pesticide poisoning (AOPP).
  
  
  METHODS
  A total of 126 AOPP patients were examined for blood copepin and IMA levels and myocardial injury markers within 1 h after admission.
  
  
  RESULTS
  Copeptin and IMA levels significantly increased in patients with AOPP compared with those in the control subjects. Copeptin and IMA levels were significantly higher in severe AOPP cases than in mild to moderate cases (P<0.05). Logistic regression analysis showed that increased copeptin and IMA levels and severe complications of AOPP were associated with an increased risk of cardiovascular events.
  
  
  CONCLUSIONS
  Early detection of copeptin and IMA levels has important clinical value in early diagnosis and prognostic evaluation of myocardial damage in patients with AOPP, and their levels are positively correlated with the severity of the condition.
authors.affiliation: Department of Emergency Medicine, Harrison International Peace Hospital, Hengshui 053000, China.E-mail: zhiyeyishi007@sina.com.cn.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Jianjun
authors.initials: J
authors.lastname: Zhang
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.forename: Jia
authors.initials: J
authors.lastname: Li
authors.forename: Juan
authors.initials: J
authors.lastname: Liu
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
mesh_terms: D015415:Biomarkers / Q000097:blood; D042241:Early Diagnosis; D006020:Glycopeptides / Q000097:blood*; D006801:Humans; D062025:Organophosphate Poisoning / Q000175:diagnosis*; D010575:Pesticides / Q000506:poisoning*; D011379:Prognosis; D012709:Serum Albumin; D000075462:Serum Albumin, Human
chemical_list: D015415:Biomarkers; D006020:Glycopeptides; D010575:Pesticides; D012709:Serum Albumin; C048197:copeptins; C561522:ischemia-modified albumin; D000075462:Serum Albumin, Human