title: Mutagenicity of drinking water sampled from the Yangtze River and Hanshui River (Wuhan section) and correlations with water quality parameters.
abstract: A total of 54 water samples were collected during three different hydrologic periods (level period, wet period, and dry period) from Plant A and Plant B (a source for Yangtze River and Hanshui River water, respectively), and several water parameters, such as chemical oxygen demand (COD), turbidity, and total organic carbon (TOC), were simultaneously analyzed. The mutagenicity of the water samples was evaluated using the Ames test with Salmonella typhimurium strains TA98 and TA100. According to the results, the organic compounds in the water were largely frame-shift mutagens, as positive results were found for most of the tests using TA98. All of the finished water samples exhibited stronger mutagenicity than the relative raw and distribution water samples, with water samples collected from Plant B presenting stronger mutagenic strength than those from Plant A. The finished water samples from Plant A displayed a seasonal-dependent variation. Water parameters including COD (r = 0.599, P = 0.009), TOC (r = 0.681, P = 0.02), UV254 (r = 0.711, P = 0.001), and total nitrogen (r = 0.570, P = 0.014) exhibited good correlations with mutagenicity (TA98), at 2.0 L/plate, which bolsters the argument of the importance of using mutagenicity as a new parameter to assess the quality of drinking water.
authors.affiliation: Department of Environmental Microbiology, Institute of Environmental Medicine, MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
authors.forename: Xuemin
authors.initials: X
authors.lastname: Lv
authors.affiliation: Department of Environmental Microbiology, Institute of Environmental Medicine, MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Department of Environmental Microbiology, Institute of Environmental Medicine, MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Yang
authors.affiliation: Department of Environmental Microbiology, Institute of Environmental Medicine, MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
authors.forename: Xiaorong
authors.initials: X
authors.lastname: Dong
authors.affiliation: Department of Environmental Microbiology, Institute of Environmental Medicine, MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
authors.forename: Kunpeng
authors.initials: K
authors.lastname: Ma
authors.affiliation: Department of Environmental Microbiology, Institute of Environmental Medicine, MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
authors.forename: Sanhua
authors.initials: S
authors.lastname: Xiao
authors.affiliation: Department of Environmental Microbiology, Institute of Environmental Medicine, MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
authors.forename: Yazhou
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Environmental Microbiology, Institute of Environmental Medicine, MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, PR China.
authors.forename: Fei
authors.initials: F
authors.lastname: Tang
mesh_terms: D002681:China; D060766:Drinking Water / Q000737:chemistry* / Q000592:standards*; D009152:Mutagenicity Tests / Q000379:methods; D009153:Mutagens / Q000032:analysis / Q000737:chemistry* / Q000633:toxicity; D045483:Rivers / Q000737:chemistry*; D014874:Water Pollutants, Chemical; D060753:Water Quality
chemical_list: D060766:Drinking Water; D009153:Mutagens; D014874:Water Pollutants, Chemical
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