title: Tris-biphenyl triazine, a new ultraviolet filter studied in terms of photoprotective efficacy.
abstract: There are relatively few authorized ultraviolet filters in Europe and this presents a certain number of problems when we want to formulate a sun protection product which both ensures a high level of protection and respects the recommendations in force in terms of broad-spectrum efficacy, with, in particular, a critical wavelength (λc) greater than or equal to 370 nm. A new ultraviolet filter has just been launched on the market. Known as tris-biphenyl triazine, it is the first filter to be registered on Annexe VI of "Cosmetics Regulation" (EC) No. 1223/2009 of the European Parliament and of the Council, which gives a list of the ultraviolet filters allowed in cosmetic products, since the regulation came into force in July 2013. This filter is both very effective (as it enables 2 SPF units and 1 UVA-PF units to be obtained respectively, by percentage of use) and very photostable (since the SPF and UVA-PF do not vary after 2h of irradiation in a solar simulator). Its broad spectrum associated with its qualities in terms of efficacy and photostability make it a choice ingredient for the formulation of sun protection products.
authors.affiliation: Université de Nantes, Nantes Atlantique Universités, MMS, EA 2160, UFR des Sciences Pharmaceutiques, 9 rue Bias, Nantes, France.
authors.forename: C
authors.initials: C
authors.lastname: Couteau
authors.affiliation: Université de Nantes, Nantes Atlantique Universités, MMS, EA 2160, UFR des Sciences Pharmaceutiques, 9 rue Bias, Nantes, France.
authors.forename: E
authors.initials: E
authors.lastname: Paparis
authors.affiliation: Pharmacochemistry Department, Faculty of Pharmacy, Nantes University, Nantes Atlantique Univerties, IICiMed UPRES EA 1155, Nantes, France.
authors.forename: C
authors.initials: C
authors.lastname: Chauvet
authors.affiliation: Université de Nantes, Nantes Atlantique Universités, MMS, EA 2160, UFR des Sciences Pharmaceutiques, 9 rue Bias, Nantes, France. Electronic address: laurence.coiffard@univ-nantes.fr.
authors.forename: L
authors.initials: L
authors.lastname: Coiffard
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000737:chemistry* / Q000494:pharmacology / Q000528:radiation effects; D002626:Chemistry, Pharmaceutical; D004355:Drug Stability; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control; D051379:Mice; D011837:Radiation-Protective Agents / Q000737:chemistry* / Q000494:pharmacology / Q000528:radiation effects; D013472:Sunlight; D013473:Sunscreening Agents / Q000737:chemistry* / Q000494:pharmacology / Q000528:radiation effects; D014227:Triazines / Q000737:chemistry* / Q000494:pharmacology / Q000528:radiation effects; D014466:Ultraviolet Rays
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001713:Biphenyl Compounds; D011837:Radiation-Protective Agents; D013473:Sunscreening Agents; D014227:Triazines
keywords: Efficacy; Photostability; Tris-biphenyl triazine; UVA-II