title: Invasive Saccharomyces cerevisiae in a liver transplant patient: case report and review of infection in transplant recipients.
abstract: Saccharomyces cerevisiae, an ascosporogenous yeast commonly used in the production of food, is an emerging infection in immunocompromised patients. We report the case of a 60-year-old man whose orthotopic liver transplant was complicated by S. cerevisiae fungemia and peritoneal abscess, successfully treated with caspofungin and drainage. We also review the literature of invasive saccharomycoses in recipients of hematologic and solid organ transplants.
authors.affiliation: Division of Infectious Diseases, McGill University Health Centre, Montreal, Quebec, Canada.
authors.forename: K Y
authors.initials: KY
authors.lastname: Popiel
authors.affiliation: Division of Gastroenterology and Hepatology, McGill University, Montreal, Quebec, Canada.
authors.forename: P
authors.initials: P
authors.lastname: Wong
authors.affiliation: Departments of Medicine, Microbiology and Immunology, McGill University, Montréal, Quebec, Canada.
authors.forename: M J
authors.initials: MJ
authors.lastname: Lee
authors.affiliation: Division of Infectious Diseases (Infectious Disease Susceptibility Program), McGill University Health Centre, Montreal, Quebec, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Langelier
authors.affiliation: Departments of Medicine, Microbiology and Immunology, McGill University, Montréal, Quebec, Canada.
authors.forename: D C
authors.initials: DC
authors.lastname: Sheppard
authors.affiliation: Division of Infectious Diseases (Infectious Disease Susceptibility Program), McGill University Health Centre, Montreal, Quebec, Canada.
authors.forename: D C
authors.identifier: http://orcid.org/0000-0003-1347-7767
authors.initials: DC
authors.lastname: Vinh
mesh_terms: D000935:Antifungal Agents / Q000008:administration & dosage*; D000077336:Caspofungin; D054714:Echinocandins / Q000008:administration & dosage*; D016469:Fungemia; D006801:Humans; D016867:Immunocompromised Host; D055666:Lipopeptides / Q000008:administration & dosage*; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D012441:Saccharomyces cerevisiae / Q000302:isolation & purification*; D066027:Transplant Recipients
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D000077336:Caspofungin
keywords: BMT; SOT; Saccharomyces cerevisiae; fungemia; transplant; yeast