title: Rough-fuzzy clustering and unsupervised feature selection for wavelet based MR image segmentation.
abstract: Image segmentation is an indispensable process in the visualization of human tissues, particularly during clinical analysis of brain magnetic resonance (MR) images. For many human experts, manual segmentation is a difficult and time consuming task, which makes an automated brain MR image segmentation method desirable. In this regard, this paper presents a new segmentation method for brain MR images, integrating judiciously the merits of rough-fuzzy computing and multiresolution image analysis technique. The proposed method assumes that the major brain tissues, namely, gray matter, white matter, and cerebrospinal fluid from the MR images are considered to have different textural properties. The dyadic wavelet analysis is used to extract the scale-space feature vector for each pixel, while the rough-fuzzy clustering is used to address the uncertainty problem of brain MR image segmentation. An unsupervised feature selection method is introduced, based on maximum relevance-maximum significance criterion, to select relevant and significant textural features for segmentation problem, while the mathematical morphology based skull stripping preprocessing step is proposed to remove the non-cerebral tissues like skull. The performance of the proposed method, along with a comparison with related approaches, is demonstrated on a set of synthetic and real brain MR images using standard validity indices.
authors.affiliation: Biomedical Imaging and Bioinformatics Lab, Machine Intelligence Unit, Indian Statistical Institute, 203 B. T. Road, Kolkata, 700 108, India.
authors.forename: Pradipta
authors.initials: P
authors.lastname: Maji
authors.affiliation: Biomedical Imaging and Bioinformatics Lab, Machine Intelligence Unit, Indian Statistical Institute, 203 B. T. Road, Kolkata, 700 108, India.
authors.forename: Shaswati
authors.initials: S
authors.lastname: Roy
mesh_terms: D000465:Algorithms; D001931:Brain Mapping / Q000379:methods*; D016000:Cluster Analysis; D017143:Fuzzy Logic; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012680:Sensitivity and Specificity; D058067:Wavelet Analysis
references.citation: Med Image Anal. 2004 Sep;8(3):275-83
references.pmid: 15450222
references.citation: Eur J Radiol. 2005 Oct;56(1):12-9
references.pmid: 16168259
references.citation: Comput Med Imaging Graph. 2009 Sep;33(6):431-41
references.pmid: 19446435
references.citation: Neuroimage. 2004;23 Suppl 1:S208-19
references.pmid: 15501092
references.citation: Med Phys. 1993 Jul-Aug;20(4):1033-48
references.pmid: 8413011
references.citation: Neuroimage. 2009 Oct 1;47(4):1394-407
references.pmid: 19389477
references.citation: Neuroimage. 2001 May;13(5):856-76
references.pmid: 11304082
references.citation: J Magn Reson Imaging. 1995 Sep-Oct;5(5):594-605
references.pmid: 8574047
references.citation: Phys Med Biol. 1996 Nov;41(11):2437-46
references.pmid: 8938037
references.citation: IEEE Trans Med Imaging. 1998 Feb;17(1):98-107
references.pmid: 9617911
references.citation: IEEE Trans Image Process. 1993;2(4):429-41
references.pmid: 18296228
references.citation: IEEE Trans Med Imaging. 1998 Apr;17(2):187-201
references.pmid: 9688151
references.citation: Biol Cybern. 1986;55(2-3):71-82
references.pmid: 3801538
references.citation: IEEE Trans Med Imaging. 2003 Aug;22(8):933-9
references.pmid: 12906247
references.citation: J Magn Reson Imaging. 2000 Mar;11(3):267-78
references.pmid: 10739558
references.citation: IEEE Trans Image Process. 2008 Sep;17(9):1709-20
references.pmid: 18713675
references.citation: IEEE Trans Med Imaging. 2003 Sep;22(9):1163-71
references.pmid: 12956271
references.citation: IEEE Trans Syst Man Cybern B Cybern. 2007 Dec;37(6):1529-40
references.pmid: 18179071
references.citation: Radiology. 1999 Sep;212(3):811-6
references.pmid: 10478251
references.citation: IEEE Trans Image Process. 1995;4(11):1549-60
references.pmid: 18291987
references.citation: Neuroimage. 2005 Jul 1;26(3):839-51
references.pmid: 15955494
references.citation: Hum Brain Mapp. 2002 Nov;17(3):143-55
references.pmid: 12391568
references.citation: Acad Radiol. 2003 Dec;10(12):1341-8
references.pmid: 14697002
references.citation: Magn Reson Imaging. 1988 Jul-Aug;6(4):463-72
references.pmid: 3185139
references.citation: IEEE/ACM Trans Comput Biol Bioinform. 2013 Mar-Apr;10(2):286-99
references.pmid: 22848138
references.citation: Artif Intell Med. 2001 Jan-Mar;21(1-3):43-63
references.pmid: 11154873
references.citation: Radiology. 2001 Feb;218(2):586-91
references.pmid: 11161183