title: [Clinical evaluation of ultrasound-guided percutaneous microwave ablation of splenic tumors].
abstract: OBJECTIVE
  To investigate the feasibility, safety and efficacy of ultrasound-guided percutaneous microwave ablation (MWA) of splenic tumors.
  
  
  METHODS
  Seven patients with 8 pathologically confirmed splenic tumors (including 2 metastases from the ovary and 4 from the lung, gastric adenocarcinoma, hepatocellular carcinoma, or rectal carcinoma; 1 hemangioma and 1 inflammatory pseudotumor) with sizes ranging from 1.3 to 6.2 cm (mean 3.1 ± 1.9 cm) were treated with MWA. A cooled shaft needle antenna was percutaneously inserted into the tumor under ultrasound guidance. A thermocouple was placed about 0.5 cm away from the tumor to monitor the temperature in real time during the ablation. The microwave emitting power was set at 50-60 W. The treatment efficacy was assessed by contrast-enhanced imaging at 1, 3 and 6 months following the procedure, and every 6 months thereafter.
  
  
  RESULTS
  All the tumors were completely ablated in a single session and no complications occurred. No local tumor progression was observed during a median follow up time of 13 months (4 to 92 months). The ablation zone, well defined on contrast-enhanced imaging, was gradually reduced with time. A new metastatic lesion was detected in the spleen at 11 months after the ablation in a ovarian carcinoma patient and was successfully treated by a second MWA. The post-ablation survival of the patients with splenic metastasis was 13 months (range 4 to 92 months). No complications other than fever and abdominal pain were observed in these patients.
  
  
  CONCLUSIONS
  Ultrasound-guided percutaneous MWA is a safe and effective minimally-invasive technique for treatment of splenic tumors in selected patients.
authors.affiliation: Department of Interventional Ultrasound, General Hospital of PLA, Beijing 100853, China.E-mail: yu-jie301@hotmail.com.
authors.forename: Jie
authors.initials: J
authors.lastname: Yu
authors.forename: Ping
authors.initials: P
authors.lastname: Liang
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Yu
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Cheng
authors.forename: Zhiyu
authors.initials: Z
authors.lastname: Han
authors.forename: Mengjuan
authors.initials: M
authors.lastname: Mu
authors.forename: Yanmei
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000473:pathology; D017115:Catheter Ablation; D003287:Contrast Media; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology; D008872:Microwaves; D019060:Minimally Invasive Surgical Procedures; D010051:Ovarian Neoplasms / Q000473:pathology; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000556:secondary; D013274:Stomach Neoplasms / Q000473:pathology; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D003287:Contrast Media