title: Intravenous Imaging Contrast Media Complications: The Basics That Every Clinician Needs to Know.
abstract: Intravenous contrast is commonly used in noninvasive imaging procedures such as magnetic resonance imaging and computed tomography and can evaluate blood vessels and better characterize soft-tissue lesions. Although the incidence of adverse events after administration of contrast is low, it is important that clinicians and radiologists minimize risks and respond quickly and effectively when reactions occur. We will discuss a range of adverse events to iodinated and gadolinium-based contrast agents, including allergic-like reactions, nephrotoxicity, extravasation, and nephrogenic systemic fibrosis. We will review risk stratification for patients, as well as premedication and treatment of adverse events.
authors.affiliation: Moffitt Cancer Center, Tampa, Fla. Electronic address: trevor.rose@moffitt.org.
authors.forename: Trevor A
authors.initials: TA
authors.lastname: Rose
authors.affiliation: Moffitt Cancer Center, Tampa, Fla.
authors.forename: Jung W
authors.initials: JW
authors.lastname: Choi
mesh_terms: D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects*; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000209:etiology; D005355:Fibrosis / Q000139:chemically induced; D005682:Gadolinium / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000139:chemically induced; D007004:Hypoglycemic Agents / Q000009:adverse effects; D007275:Injections, Intravenous; D007457:Iodine Radioisotopes / Q000008:administration & dosage / Q000009:adverse effects; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000139:chemically induced; D008687:Metformin / Q000009:adverse effects; D011868:Radioisotopes / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D003287:Contrast Media; D007004:Hypoglycemic Agents; D007457:Iodine Radioisotopes; D011868:Radioisotopes; D008687:Metformin; D005682:Gadolinium
keywords: Allergy; Complications; Contrast; Extravasation; Fibrosis; Gadolinium; Induced; Intravenous; Metformin; Nephrogenic; Nephropathy; Systemic