title: The ambidextrous cyclooxygenase: an enduring target.
abstract: With the discovery of COX, pain has not been treated in a relentless manner. Numbers of drugs with fewer side effects were discovered and are used successfully for treatment of pain. With new research coming into being since the discovery of COX, it was established that COX can be targeted not only for treatment of pain but for curing various diseases like cancer, Alzheimer's, Parkinson's disease, Glaucoma etc. With the sighting of COX-3, another isoform of COX, new diseases are being targeted for better treatment.
authors.affiliation: Department of Pharmaceutical Chemistry, Shivam Pharmaceutical Studies and Research Center, Anand-Sojithra Road, Valasan, Anand-Gujarat, India. mayankbapna@yahoo.com.
authors.forename: Mayank
authors.initials: M
authors.lastname: Bapna
authors.forename: Lalit Singh
authors.initials: LS
authors.lastname: Chauhan
mesh_terms: D000818:Animals; D051545:Cyclooxygenase 1 / Q000187:drug effects / Q000378:metabolism; D051546:Cyclooxygenase 2 / Q000187:drug effects / Q000378:metabolism; D052246:Cyclooxygenase 2 Inhibitors / Q000627:therapeutic use; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D011451:Prostaglandin-Endoperoxide Synthases / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism
chemical_list: D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D051545:Cyclooxygenase 1; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases; C466421:cyclooxygenase-3