title: Diabetic cardiomyopathy and the role of mitochondrial dysfunction: novel insights, mechanisms, and therapeutic strategies.
abstract: This Forum addresses the role of mitochondrial dysfunction in the multifactorial nature of diabetic cardiomyopathy (DCM) from multiple angles. Contributors deliver a diverse and in-depth view of the state-of-the-art in DCM, from bench to bedside. What emerges is a picture of mitochondrial dysfunction as a central upstream defect, inflicted on the heart by diabetes. Collectively, the authors pinpoint high-value knowledge gaps, propose new conceptual frameworks, and highlight understudied, but promising, research themes.
authors.affiliation: Division of Cardiology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Aon
authors.affiliation: Division of Cardiology, School of Medicine, Johns Hopkins University, Baltimore, Maryland.
authors.forename: D Brian
authors.initials: DB
authors.lastname: Foster
mesh_terms: D000818:Animals; D048909:Diabetes Complications / Q000378:metabolism / Q000473:pathology; D058065:Diabetic Cardiomyopathies / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D008929:Mitochondria, Heart / Q000378:metabolism*; D018482:Muscle, Skeletal / Q000378:metabolism / Q000473:pathology; D009206:Myocardium / Q000378:metabolism / Q000473:pathology