title: 7 Tesla MRI in cerebral small vessel disease.
abstract: Cerebral small vessel disease (SVD) is a major cause of stroke and cognitive decline. Magnetic resonance imaging (MRI) currently plays a central role in diagnosis, and advanced MRI techniques are widely used in research but are limited by spatial resolution. Human 7 Tesla (7T) MRI has recently become available offering the ability to image at higher spatial resolution. This may provide additional insights into both the vascular pathology itself as well as parenchymal markers which could only previously be examined post mortem. In this review we cover the advantages and limitations of 7T MRI, review studies in SVD performed to date, and discuss potential future insights into SVD which 7T MRI may provide.
authors.affiliation: Neurosciences Research Centre, St George's University of London, London, UK.
authors.forename: Philip
authors.initials: P
authors.lastname: Benjamin
authors.affiliation: Functional MRI of the Brain (FMRIB) Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
authors.forename: Olivia
authors.initials: O
authors.lastname: Viessmann
authors.affiliation: Atkinson Morley Regional Neuroscience Centre, St George's NHS Healthcare Trust, London, UK.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: MacKinnon
authors.affiliation: Functional MRI of the Brain (FMRIB) Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
authors.forename: Peter
authors.initials: P
authors.lastname: Jezzard
authors.affiliation: Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
authors.forename: Hugh S
authors.initials: HS
authors.lastname: Markus
mesh_terms: D059345:Cerebral Small Vessel Diseases / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods
keywords: : 7T MRI; small vessel disease