title: [Molecular diagnostics in neuropathology].
abstract: As in only few other areas of oncology, molecular markers in neurooncology have become an integral part of clinical decision-making. This development is driven by a bustling scientific activity exploring the molecular basis and pathogenesis of human brain tumors. In addition, a high percentage of brain tumor patients are included in clinical studies in which molecular markers are assessed and linked with clinical informativeness. First steps towards more differentiated therapeutic strategies against brain tumors have thus been taken. The implementation in the clinical and diagnostic routine requires a detailed knowledge and a close collaboration between all medical disciplines involved.
authors.affiliation: Institut für Pathologie, Zentrum für molekularpathologische Diagnostik, Universität Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Deutschland, Wolfgang.Dietmaier@ukr.de.
authors.forename: W
authors.initials: W
authors.lastname: Dietmaier
authors.forename: J
authors.initials: J
authors.lastname: Lorenz
authors.forename: M J
authors.initials: MJ
authors.lastname: Riemenschneider
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000235:genetics* / Q000473:pathology* / Q000628:therapy; D002528:Cerebellar Neoplasms / Q000235:genetics / Q000473:pathology / Q000628:therapy; D002648:Child; D000066491:Clinical Decision-Making; D003299:Cooperative Behavior; D004252:DNA Mutational Analysis; D005819:Genetic Markers / Q000235:genetics*; D005910:Glioma / Q000235:genetics / Q000473:pathology / Q000628:therapy; D006801:Humans; D033183:Interdisciplinary Communication; D008527:Medulloblastoma / Q000235:genetics / Q000473:pathology / Q000628:therapy; D025202:Molecular Diagnostic Techniques; D009837:Oligodendroglioma / Q000235:genetics / Q000473:pathology / Q000628:therapy; D011379:Prognosis
chemical_list: D005819:Genetic Markers
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