title: Patients with ocular symptoms referred for electrodiagnosis: how many of them suffer from myasthenia gravis?
abstract: The aim of this study was the diagnosis of patients with isolated ocular manifestations (ptosis and/or diplopia) referred for electrophysiological evaluation to the electrodiagnostic laboratory of a University Neurological Department. Examination was performed either in inpatient status or in outpatient basis. We analyzed the clinical, electrophysiological and other laboratory data in 79 subjects. Myasthenia gravis (MG) was diagnosed in 38 %, 45.6 % in other diseases (Graves disease, blepharospasm, IIId cranial verve palsy, multiple sclerosis, stroke, etc.), while in 16.5 %, the cause remained unidentified. Symptoms fluctuation was significantly more frequent in the myasthenic patients, compared to patients with other diseases. The presence of both diplopia and ptosis are more likely due to MG rather than other pathology.
authors.affiliation: Department of Neurology, EMG Laboratory, University of Athens, Aeginition Hospital, 74, Vass. Sofias Ave., 115-28, Athens, Greece. tzabelis@med.uoa.gr.
authors.forename: Th
authors.initials: T
authors.lastname: Zambelis
authors.affiliation: Department of Neurology, EMG Laboratory, University of Athens, Aeginition Hospital, 74, Vass. Sofias Ave., 115-28, Athens, Greece.
authors.forename: V
authors.initials: V
authors.lastname: Pappas
authors.affiliation: Department of Neurology, EMG Laboratory, University of Athens, Aeginition Hospital, 74, Vass. Sofias Ave., 115-28, Athens, Greece.
authors.forename: P
authors.initials: P
authors.lastname: Kokotis
authors.affiliation: Department of Neurology, EMG Laboratory, University of Athens, Aeginition Hospital, 74, Vass. Sofias Ave., 115-28, Athens, Greece.
authors.forename: V
authors.initials: V
authors.lastname: Zouvelou
authors.affiliation: Department of Neurology, EMG Laboratory, University of Athens, Aeginition Hospital, 74, Vass. Sofias Ave., 115-28, Athens, Greece.
authors.forename: N
authors.initials: N
authors.lastname: Karandreas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001763:Blepharoptosis / Q000175:diagnosis / Q000209:etiology; D004172:Diplopia / Q000175:diagnosis / Q000209:etiology; D004568:Electrodiagnosis; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications*; D012189:Retrospective Studies; D014786:Vision Disorders / Q000145:classification / Q000175:diagnosis* / Q000209:etiology*; D055815:Young Adult
keywords: Diplopia; Myasthenia gravis; Ptosis