title: Pitfalls in the pathological diagnosis of lymphoma.
abstract: Since the publication of the 2008 World Health Organization classifications of lymphoma, additional immunohistochemical tests and other ancillary methods such as flow cytometry, cytogenetic and other molecular biology techniques, have been applied in routine clinical work. Due to the utilization of these methodologies, there has been great progress in the pathological diagnosis and classification of lymphomas in the mainland of China. Nonetheless, lymphoma pathology still remains very challenging in the field of diagnostic pathology. Ten percent of pathologist's annual consultation cases are lymphomas, thus reflecting the difficulty of this field. Here, we summarize the common misdiagnoses and pitfalls when dealing with lymphoma cases, the cause of the errors and strategies to avoid inaccurate diagnoses.
authors.affiliation: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Pathology, Peking University Cancer Hospital & Institute, Beijing 100142, China. xhli72@163.com.
authors.forename: Xianghong
authors.initials: X
authors.lastname: Li
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis / Q000235:genetics; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000517:prevention & control*; D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000737:chemistry / Q000145:classification / Q000235:genetics / Q000473:pathology*; D025202:Molecular Diagnostic Techniques; D015588:Observer Variation; D011237:Predictive Value of Tests; D011379:Prognosis; D015203:Reproducibility of Results; D013048:Specimen Handling
chemical_list: D014408:Biomarkers, Tumor
keywords: Lymphoma; diagnosis; pitfalls