title: Progression of conjunctival primary acquired melanosis (PAM) to widely spreaded malignant melanoma.
abstract: Primary acquired melanosis (PAM) is an acquired pigmentation of the conjunctival epithelium, a preinvasive pigmented lesion. When it is associated with cellular atypia it can lead to the developement of melanoma. We report a case report of malignant melanoma of the conjuntiva, which arrised from the conjuntival PAM. The disease was too extensive for ocular conservation, therefore exenteration was performed. This case highlights the need for regular follow-up of patients with melanocytic lesions of the ocular adnexa, and particular attention to the surgical technique, and careful follow-up to detect further disease activity.
authors.forename: Sonja
authors.initials: S
authors.lastname: Jandroković
authors.forename: Smiljka
authors.initials: S
authors.lastname: Popović-Suić
authors.forename: Jelena Juri
authors.initials: JJ
authors.lastname: Mandić
authors.forename: Tomislav
authors.initials: T
authors.lastname: Kuzman
authors.forename: Ivan
authors.initials: I
authors.lastname: Skegro
authors.forename: Marija Barisić
authors.initials: MB
authors.lastname: Kutija
authors.forename: Sanja
authors.initials: S
authors.lastname: Masnec
authors.forename: Miro
authors.initials: M
authors.lastname: Kalauz
mesh_terms: D000368:Aged; D003230:Conjunctival Neoplasms / Q000473:pathology* / Q000601:surgery; D018450:Disease Progression; D005260:Female; D006801:Humans; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008548:Melanosis / Q000473:pathology*