title: Ebola: a holistic approach is required to achieve effective management and control.
abstract: The current Ebola outbreak in West Africa has already caused substantial mortality and dire human and economic consequences. It continues to represent an alarming public health threat in the region and beyond and jeopardizes the provision of health care and other services in the affected countries. The scale of the epidemic has accelerated research efforts for diagnostics, treatment, and prevention galvanized through increased availability of funding. Our knowledge relating to the virus, disease pathogenesis, risk factors, dynamics of transmission, and epidemic control is increasing, and sociocultural factors have emerged as critical determinants for the success and failure of control efforts. However, there is a long way to go. In this review we summarize the current knowledge, examine the sociocultural context in West Africa, and outline priority areas for future research.
authors.affiliation: The Medical Research Unit (MRC), Fajara, The Gambia.
authors.forename: Anna
authors.initials: A
authors.lastname: Roca
authors.affiliation: The Medical Research Unit (MRC), Fajara, The Gambia.
authors.forename: Muhammed O
authors.initials: MO
authors.lastname: Afolabi
authors.affiliation: The Medical Research Unit (MRC), Fajara, The Gambia.
authors.forename: Yauba
authors.initials: Y
authors.lastname: Saidu
authors.affiliation: The Medical Research Unit (MRC), Fajara, The Gambia; Imperial College London, London, United Kingdom. Electronic address: bkampmann@mrc.gm.
authors.forename: Beate
authors.initials: B
authors.lastname: Kampmann
mesh_terms: D000349:Africa / Q000453:epidemiology; D000884:Anthropology, Cultural; D003695:Delivery of Health Care; D019468:Disease Management; D004196:Disease Outbreaks; D026690:Ethics, Clinical; D019142:Hemorrhagic Fever, Ebola / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control* / Q000628:therapy*; D006801:Humans; D012307:Risk Factors
keywords: Ebola virus disease; West Africa; containment; holistic; viral hemorrhagic fever
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