title: Bullous systemic lupus erythematosus associated with esophagitis dissecans superficialis.
abstract: Bullous systemic lupus erythematosus is one of the rare autoantibody mediated skin manifestation of systemic lupus erythematosus (SLE) demonstrating subepidermal blistering with neutrophilic infiltrate histologically. We present a case of a 40-year-old Hispanic female who presented with a several months' history of multiple blistering pruritic skin lesions involving the face and trunk, a photosensitive rash over the face and neck, swelling of the right neck lymph node, and joint pain involving her elbows and wrist. Her malady was diagnosed as bullous systemic lupus erythematosus based on the immunological workup and biopsy of her skin lesions. The patient also complained of odynophagia and endoscopy revealed esophagitis dissecans superficialis which is a rare endoscopic finding characterized by sloughing of the esophageal mucosa. The bullous disorders typically associated with esophagitis dissecans superficialis are pemphigus and rarely bullous pemphigoid. However, this is the first reported case of bullous systemic lupus erythematosus associated with esophagitis dissecans superficialis.
authors.affiliation: Department of Medicine, Interfaith Medical Center, Brooklyn, NY 11213, USA.
authors.forename: Meera
authors.identifier: 0000-0002-3120-2700
authors.initials: M
authors.lastname: Yogarajah
authors.affiliation: Department of Medicine, Interfaith Medical Center, Brooklyn, NY 11213, USA.
authors.forename: Bhradeev
authors.identifier: 0000-0001-6988-8296
authors.initials: B
authors.lastname: Sivasambu
authors.affiliation: Department of Medicine, Interfaith Medical Center, Brooklyn, NY 11213, USA.
authors.forename: Eric A
authors.initials: EA
authors.lastname: Jaffe
references.citation: Ann N Y Acad Sci. 2009 Sep;1173:203-10
references.pmid: 19758152
references.citation: Arch Dermatol. 1973 Jan;107(1):118-20
references.pmid: 4566188
references.citation: Arch Dermatol. 1999 May;135(5):569-73
references.pmid: 10328198
references.citation: Arch Dermatol. 1969 Jan;99(1):17-25
references.pmid: 4178218
references.citation: J Am Acad Dermatol. 1992 Jul;27(1):79-87
references.pmid: 1619081
references.citation: Arch Dermatol. 1995 Jan;131(1):48-52
references.pmid: 7826096
references.citation: Arch Dermatol. 1978 Aug;114(8):1187-90
references.pmid: 354534
references.citation: Endoscopy. 2007 Feb;39 Suppl 1:E127
references.pmid: 17440858
references.citation: Clin Dermatol. 2004 Mar-Apr;22(2):129-38
references.pmid: 15234014
references.citation: Dermatol Clin. 1993 Jul;11(3):535-47
references.pmid: 8365038
references.citation: J Am Acad Dermatol. 1981 Jun;4(6):682-7
references.pmid: 7016940
references.citation: Ann Intern Med. 1982 Aug;97(2):165-70
references.pmid: 7049027
references.citation: Niger J Med. 2013 Oct-Dec;22(4):354-6
references.pmid: 24283100
references.citation: Am J Surg Pathol. 2009 Dec;33(12):1789-94
references.pmid: 19809273
references.citation: Endoscopy. 2007 Feb;39 Suppl 1:E91
references.pmid: 17440869
references.citation: Autoimmune Dis. 2012;2012:834291
references.pmid: 22888407
references.citation: N Engl J Med. 1984 Apr 19;310(16):1007-13
references.pmid: 6369131
references.citation: Gastrointest Endosc. 2003 Jan;57(1):140-1
references.pmid: 12518158
references.citation: J Am Acad Dermatol. 1983 Dec;9(6):924-33
references.pmid: 6358284
references.citation: Lupus. 2010 Aug;19(9):1050-70
references.pmid: 20693199