title: Editorial commentary: autologous chondrocyte implantation versus microfracture.
abstract: Autologous chondrocyte implantation (ACI) shows greater durability, lower failure rates, and is effective for larger lesions, compared with microfracture. In addition, membrane-ACI (M-ACI) is technically simpler with fewer complications of cartilage hypertrophy than first-generation ACI using periosteum. However, second-generation, M-ACI is not yet approved for general use in the United States.
authors.forename: James H
authors.initials: JH
authors.lastname: Lubowitz
mesh_terms: D054544:Arthroplasty, Subchondral; D002357:Cartilage Diseases / Q000601:surgery*; D002358:Cartilage, Articular / Q000601:surgery*; D019902:Chondrocytes / Q000637:transplantation*; D006801:Humans; D007719:Knee Joint / Q000601:surgery*