title: Multi-modality neuro-monitoring: conventional clinical trial design.
abstract: Multi-modal monitoring has become an integral part of neurointensive care. However, our approach is at this time neither standardized nor backed by data from randomized controlled trials. The goal of the second Neurocritical Care Research Conference was to discuss research priorities in multi-modal monitoring, what research tools are available, as well as the latest advances in clinical trial design. This section of the meeting was focused on how such a trial should be designed so as to maximize yield and avoid mistakes of the past.
authors.affiliation: Division of Neurocritical Care and Vascular Neurology, Department of Neurology, Baylor College of Medicine, 6501 Fannin Street, MS: NB320, Houston, TX, 77030, USA, jisuarez@bcm.tmc.edu.
authors.forename: Alexandros L
authors.initials: AL
authors.lastname: Georgiadis
authors.forename: Yuko Y
authors.initials: YY
authors.lastname: Palesch
authors.forename: David
authors.initials: D
authors.lastname: Zygun
authors.forename: J Claude
authors.initials: JC
authors.lastname: Hemphill
authors.forename: Claudia S
authors.initials: CS
authors.lastname: Robertson
authors.forename: Peter D
authors.initials: PD
authors.lastname: Leroux
authors.forename: Jose I
authors.initials: JI
authors.lastname: Suarez
mesh_terms: D002986:Clinical Trials as Topic; D003422:Critical Care / Q000379:methods*; D006801:Humans; D064926:Neurophysiological Monitoring / Q000379:methods*; D012107:Research Design
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