title: [Reversion of sedation and general anaesthesia--agonist-antagonist technique].
abstract: OBJECTIVE
  To study an expediency and efficacy of application of different reverses drugs (naloxone, flumazenil, neostigmine, galantamine, sugammadex) either their separate or combined using.
  
  
  METHODS
  We studied 119 patients underwent endoluminal endoscopic procedures and surgeries on trachea-bronchial tree and intestines under sedation or general anaesthesia.
  
  
  RESULTS
  The article deals with conceptual approaches to the reversal of residual effects of opioids, benzodiazepine sedation and neuromuscular block (the so-called agonist-antagonist technique).
  
  
  CONCLUSIONS
  A reversion of neuromuscular block without using of antagonists' combination does not provide complete recovery of psychomotor and cognitive functions for rapid socialization of patients after anaesthesia.
authors.forename: O B
authors.initials: OB
authors.lastname: Matveeva
authors.forename: V M
authors.initials: VM
authors.lastname: Mizikov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000762:Anesthesia Recovery Period; D000768:Anesthesia, General / Q000379:methods*; D018681:Anesthetics, General / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D001794:Blood Pressure / Q000187:drug effects; D018680:Cholinergic Antagonists / Q000008:administration & dosage* / Q000009:adverse effects; D054810:Deep Sedation / Q000379:methods*; D004359:Drug Therapy, Combination; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects / Q000037:antagonists & inhibitors* / Q000493:pharmacokinetics; D008297:Male; D008875:Middle Aged; D009292:Narcotic Antagonists / Q000008:administration & dosage* / Q000009:adverse effects; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000037:antagonists & inhibitors* / Q000493:pharmacokinetics; D055815:Young Adult
chemical_list: D018681:Anesthetics, General; D018680:Cholinergic Antagonists; D006993:Hypnotics and Sedatives; D009292:Narcotic Antagonists; D009466:Neuromuscular Blocking Agents