title: Asymmetric hydrogenation of aromatic ketones by new recyclable ionic tagged ferrocene-ruthenium catalyst system.
abstract: Newly developed ferrocene-oxazoline-phosphine ligands containing quaternary ammonium ionic groups exhibited excellent catalytic performance for the ruthenium-catalyzed hydrogenation of aromatic ketonic substrates to give chiral secondary alcohols with high levels of conversions and enantioselectivities. Simple manipulation process, water tolerance, high activity and good recyclable property make this catalysis practical and appealing.
authors.affiliation: R&D Center for Pharmaceuticals, School of Chemical Engineering and the Environment, Beijing Institute of Technology, Beijing 100081, PR China.
authors.forename: Di
authors.initials: D
authors.lastname: Xu
authors.affiliation: R&D Center for Pharmaceuticals, School of Chemical Engineering and the Environment, Beijing Institute of Technology, Beijing 100081, PR China; State Key Laboratory of Explosion Science and Technology, Beijing Institute of Technology, Beijing 100081, PR China.
authors.forename: Zhi-Ming
authors.initials: ZM
authors.lastname: Zhou
authors.affiliation: R&D Center for Pharmaceuticals, School of Chemical Engineering and the Environment, Beijing Institute of Technology, Beijing 100081, PR China.
authors.forename: Li
authors.initials: L
authors.lastname: Dai
authors.affiliation: R&D Center for Pharmaceuticals, School of Chemical Engineering and the Environment, Beijing Institute of Technology, Beijing 100081, PR China.
authors.forename: Li-Wei
authors.initials: LW
authors.lastname: Tang
authors.affiliation: R&D Center for Pharmaceuticals, School of Chemical Engineering and the Environment, Beijing Institute of Technology, Beijing 100081, PR China. Electronic address: zhangjun603@bit.edu.cn.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D005296:Ferrous Compounds / Q000737:chemistry*; D006865:Hydrogenation; D007659:Ketones / Q000737:chemistry*; D000075163:Metallocenes; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000438:Alcohols; D005296:Ferrous Compounds; D007659:Ketones; D000075163:Metallocenes; D009942:Organometallic Compounds; D012428:Ruthenium; C004998:ferrocene
keywords: Enantioselectivity; Ferrocene; Hydrogenation; Ionic liquid; Recovery; Ruthenium