title: Randomized comparative efficacy study of parent-mediated interventions for toddlers with autism.
abstract: OBJECTIVE
  This study compared effects of two parent-mediated interventions on joint engagement outcomes as augmentations of an early intervention program for toddlers with autism spectrum disorder (ASD).
  
  
  METHODS
  Participants included 86 toddlers (range 22-36 months) with ASD and their primary caregiver. Caregiver-child dyads were randomized to receive 10 weeks of hands-on parent training in a naturalistic, developmental behavioral intervention (joint attention, symbolic play, engagement and regulation-JASPER) or a parent-only psychoeducational intervention (PEI). Dose was controlled in terms of researcher-parent contact and early intervention services received by the child.
  
  
  RESULTS
  Results yielded significant effects of the JASPER intervention on the primary outcome of joint engagement. The treatment effect was large (Cohen's f² = .69) and maintained over the 6-month follow-up. JASPER effects were also found on secondary outcomes of play diversity, highest play level achieved, and generalization to the child's classroom for child-initiated joint engagement. The PEI intervention was found to be effective in reducing parenting stress associated with child characteristics. All secondary effects were generally small to moderate.
  
  
  CONCLUSIONS
  These data highlight the benefit of a brief, targeted, parent-mediated intervention on child outcomes. Future studies may consider the combination of JASPER and PEI treatments for optimal parent and child outcomes. Trial registry no. NCT00999778.
authors.affiliation: Department of Human Development and Psychology, University of California Los Angeles.
authors.forename: Connie
authors.initials: C
authors.lastname: Kasari
authors.affiliation: Department of Child Psychiatry, University of California Los Angeles.
authors.forename: Amanda
authors.initials: A
authors.lastname: Gulsrud
authors.affiliation: Department of Child Psychiatry, University of California Los Angeles.
authors.forename: Tanya
authors.initials: T
authors.lastname: Paparella
authors.affiliation: Semel Institute Biostatistics Core, University of California Los Angeles.
authors.forename: Gerhard
authors.initials: G
authors.lastname: Hellemann
authors.affiliation: Department of Human Development and Psychology, University of California Los Angeles.
authors.forename: Kathleen
authors.initials: K
authors.lastname: Berry
mesh_terms: D000067877:Autism Spectrum Disorder / Q000523:psychology / Q000628:therapy*; D001321:Autistic Disorder / Q000628:therapy*; D001521:Behavior Therapy / Q000379:methods*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010287:Parent-Child Relations; D010290:Parents / Q000193:education*; D016896:Treatment Outcome
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