title: Role of cardiac ultrafast cameras with CZT solid-state detectors and software developments on radiation absorbed dose reduction to the patients.
abstract: Myocardial perfusion imaging (MPI) is one the most contributing nuclear medicine technique to the annual population dose. The purpose of this study is to compare radiation-absorbed doses to the patients examined by conventional cardiac SPECT (CSPECT) camera and ultrafast cardiac (UFC) camera with cadmium-zinc-telluride (CZT) solid-state detectors. Total injected activity was reduced by 50 % when both stress and rest images were acquired and by 75 % when only stress images were taken with UFC camera. As a result of this, the mean total effective dose was found significantly lower with UFC camera (2.2 ± 1.2 mSv) than CSPECT (7.7 ± 3.8 mSv) (p < 0.001). Further dose reduction was obtained by reducing equivocal test results and unnecessary additional examinations with UFC camera. Using UFC camera, MPI can be conveniently used for the detection of coronary artery disease (CAD) much less increasing annual population radiation dose as it had been before.
authors.affiliation: Department of Nuclear Medicine, Gulhane Military Medical Academy and Faculty, Ankara 06018, Turkey bgunalp@yahoo.com.
authors.forename: Bengul
authors.initials: B
authors.lastname: Gunalp
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D002104:Cadmium; D005080:Exercise Test; D005260:Female; D015902:Gamma Cameras; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging / Q000379:methods*; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011835:Radiation Protection; D011874:Radiometry / Q000379:methods*; D019275:Radiopharmaceuticals; D012984:Software; D017256:Technetium Tc 99m Sestamibi; D013691:Tellurium; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods; D015032:Zinc
chemical_list: C474490:CdZnTe; D019275:Radiopharmaceuticals; D002104:Cadmium; D017256:Technetium Tc 99m Sestamibi; D015032:Zinc; D013691:Tellurium