title: Appraisal of the remineralizing potential of child formula dentifrices on primary teeth: An in vitro pH cycling model.
abstract: OBJECTIVE
  To evaluate the remineralizing potential of child formula dentifrices on primary teeth using an in vitro 7 days pH cycling model.
  
  
  METHODS
  Twenty-one primary teeth were placed in demineralizing solution for 96 h to produce artificial carious lesions; then cut longitudinally into 100-150 μm thick sections and randomly assigned to three groups. Sections in Group A were treated with dentifrice containing 458 ppm monofluorophosphate (MFP) and sections in Group B with 500 ppm sodium fluoride (NaF). Group C sections were treated with a nonfluoridated dentifrice.
  
  
  RESULTS
  Group A (458 ppm MFP) and Group B (500 ppm NaF) showed significant decrease in lesion depth, whereas Group C (non F) showed a significant increase in depth (P ≤ 0.05, paired t-test).
  
  
  CONCLUSIONS
  Though dentifrices containing 458 ppm MFP and 500 ppm NaF demonstrated remineralization of carious lesions, it was not complete. Therefore, it is also important to emphasize on other preventive methods in the prevention and/or reversal of carious lesions.
authors.affiliation: Department of Paedodontics and Preventive Dentistry, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: M
authors.initials: M
authors.lastname: Kiranmayi
authors.affiliation: Department of Paedodontics and Preventive Dentistry, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: S V S G
authors.initials: SV
authors.lastname: Nirmala
authors.affiliation: Department of Paedodontics and Preventive Dentistry, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: Sivakumar
authors.initials: S
authors.lastname: Nuvvula
keywords: Artificial caries; fluoride dentifrices; pH cycling; primary teeth
references.citation: Int J Paediatr Dent. 2001 Jul;11(4):266-73
references.pmid: 11570442
references.citation: Int Dent J. 1994 Jun;44(3 Suppl 1):287-95
references.pmid: 7960167
references.citation: Caries Res. 1992;26(4):254-62
references.pmid: 1423439
references.citation: Int Dent J. 1994 Jun;44(3 Suppl 1):275-85
references.pmid: 7960166
references.citation: ASDC J Dent Child. 1987 Jul-Aug;54(4):241-4
references.pmid: 3476523
references.citation: Crit Rev Oral Biol Med. 1997;8(2):136-53
references.pmid: 9167089
references.citation: J Dent Res. 1992 Apr;71 Spec No:856-9
references.pmid: 1592974
references.citation: Arch Oral Biol. 1986;31(4):201-4
references.pmid: 3459409
references.citation: J Dent Res. 1990 Feb;69 Spec No:780-5; discussion 820-3
references.pmid: 2179341
references.citation: Int J Dent Hyg. 2003 Feb;1(1):3-8
references.pmid: 16451540
references.citation: Clin Prev Dent. 1988 May-Jun;10(3):14-6
references.pmid: 3214993
references.citation: J Dent Res. 2008 Mar;87(3):224-7
references.pmid: 18296604
references.citation: Aust Dent J. 2008 Mar;53(1):34-40
references.pmid: 18304239
references.citation: Int Dent J. 2005 Aug;55(4):217-23
references.pmid: 16167610
references.citation: Am J Dent. 2005 Jun;18(3):212-6
references.pmid: 16158814
references.citation: ASDC J Dent Child. 1989 Sep-Oct;56(5):337-47
references.pmid: 2549106
references.citation: Int J Paediatr Dent. 2011 Mar;21(2):132-40
references.pmid: 21121988
references.citation: Caries Res. 1987;21(2):126-40
references.pmid: 3469028
references.citation: J Appl Oral Sci. 2003 Jun;11(2):150-6
references.pmid: 21409329
references.citation: Adv Dent Res. 1994 Jul;8(2):185-9
references.pmid: 7865074
references.citation: Caries Res. 1982;16(3):201-10
references.pmid: 6953998
references.citation: J Dent Res. 1995 Feb;74(2):691-7
references.pmid: 7722067
references.citation: Caries Res. 1981;15(5):363-8
references.pmid: 6942919
references.citation: ASDC J Dent Child. 1989 Jul-Aug;56(4):270-60
references.pmid: 2668365
references.citation: Community Dent Oral Epidemiol. 2004 Oct;32(5):319-21
references.pmid: 15341615
references.citation: Int Dent J. 1994 Jun;44(3 Suppl 1):263-73
references.pmid: 7960165
references.citation: Int Dent J. 2007 Aug;57(4):243-8
references.pmid: 17849682
references.citation: ASDC J Dent Child. 2001 Sep-Dec;68(5-6):304-10, 300
references.pmid: 11985188
references.citation: Caries Res. 1990;24(3):174-80
references.pmid: 2364402
references.citation: Acta Odontol Scand. 1999 Dec;57(6):325-9
references.pmid: 10777135
references.citation: Am J Dent. 1993 Sep;6 Spec No:S7-12
references.pmid: 7488359
references.citation: Caries Res. 1993;27(4):337-60
references.pmid: 8402812
references.citation: Int Dent J. 2007 Oct;57(5):307-13
references.pmid: 17992915