title: Placental findings of IUGR and non-IUGR.
abstract: This study aims to define the placental findings in intrauterine growth restriction (IUGR). The study group consisted of 40 neonates without IUGR and 24 neonates with IUGR, including their placentas. The cases were separated into three groups according to gestational age. Group A (n=21): 37 ≤ weeks, Group B (n=27): 32≤ - <37 weeks, Group C (n=16): < 32 weeks. Each group had two subgroups, IUGR and non-IUGR. The placentas from the non-IUGR subgroup were heavier than the IUGR subgroup placentas in the term group (p<0.05). Infarct (over 5%), increased syncytial knots and histiocytic intervillositis were more common in the IUGR cases (p<0.05). This study shows that chronic patterns of injury are significantly increased in placentas from pregnancies complicated by IUGR. If the injury in the placenta is acute or mild, fetal adaptation can compensate and prevent fetal growth restriction.
authors.affiliation: Neonatology Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey. duyguiskender@gmail.com.
authors.forename: Duygu
authors.initials: D
authors.lastname: İskender-Mazman
authors.forename: Zuhal
authors.initials: Z
authors.lastname: Akçören
authors.forename: Şule
authors.initials: Ş
authors.lastname: Yiğit
authors.forename: Gülsev
authors.initials: G
authors.lastname: Kale
authors.forename: Ayşe
authors.initials: A
authors.lastname: Korkmaz
authors.forename: Murat
authors.initials: M
authors.lastname: Yurdakök
authors.forename: Tekin
authors.initials: T
authors.lastname: Durukan
mesh_terms: D000328:Adult; D005260:Female; D005317:Fetal Growth Retardation / Q000473:pathology*; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy