title: Nine challenges in incorporating the dynamics of behaviour in infectious diseases models.
abstract: Traditionally, the spread of infectious diseases in human populations has been modelled with static parameters. These parameters, however, can change when individuals change their behaviour. If these changes are themselves influenced by the disease dynamics, there is scope for mechanistic models of behaviour to improve our understanding of this interaction. Here, we present challenges in modelling changes in behaviour relating to disease dynamics, specifically: how to incorporate behavioural changes in models of infectious disease dynamics, how to inform measurement of relevant behaviour to parameterise such models, and how to determine the impact of behavioural changes on observed disease dynamics.
authors.affiliation: Centre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK. Electronic address: sebastian.funk@lshtm.ac.uk.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Funk
authors.affiliation: Department of Biology, Georgetown University, Washington, DC 20057, USA; Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Shweta
authors.initials: S
authors.lastname: Bansal
authors.affiliation: Department of Applied Mathematics, University of Waterloo, Waterloo, ON N2L 3G1, Canada.
authors.forename: Chris T
authors.initials: CT
authors.lastname: Bauch
authors.affiliation: Centre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.
authors.forename: Ken T D
authors.initials: KT
authors.lastname: Eames
authors.affiliation: Centre for the Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.
authors.forename: W John
authors.initials: WJ
authors.lastname: Edmunds
authors.affiliation: School of Public Health, Yale University, New Haven, CT 06520, USA.
authors.forename: Alison P
authors.initials: AP
authors.lastname: Galvani
authors.affiliation: Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge CB3 0WA, UK.
authors.forename: Petra
authors.initials: P
authors.lastname: Klepac
mesh_terms: D003140:Communicable Disease Control / Q000379:methods; D003141:Communicable Diseases / Q000453:epidemiology / Q000523:psychology*; D015438:Health Behavior; D006293:Health Promotion; D006801:Humans; D015233:Models, Statistical; D011157:Population Dynamics; D011159:Population Surveillance; D014195:Travel / Q000706:statistics & numerical data
keywords: Behaviour; Infectious disease dynamics; Model; Movement and travel; Real-time data collection; Reporting