title: Liver regeneration following repeat SBRT.
abstract: Liver stereotactic body radiation therapy (SBRT) is an emerging treatment option for oligometastases and may confer a survival benefit in select patients. Herein, we document the first case of liver regeneration (LR) following repeat right hepatic lobe SBRT in a woman with breast cancer metastases. Retraction of the treated lobe was significant with a near 50% volume reduction. Compensatory contralateral lobe hypertrophy was noted with a 320% volume increase. The overall liver volume remained stable, within ±5% of baseline. This case indicates that repeat liver SBRT can be delivered safely to individual patients and that compensatory contralateral lobe hypertrophy is observed to maintain a functional liver volume.
authors.affiliation: 1 Department of Radiation Oncology, Baylor College of Medicine, Houston, TX, USA ; 2 Division of Oncology, Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA ; 3 Department of Radiation Oncology, Houston Methodist Hospital, Cancer Center and Research Institute, Houston, TX 77030, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Farach
authors.affiliation: 1 Department of Radiation Oncology, Baylor College of Medicine, Houston, TX, USA ; 2 Division of Oncology, Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA ; 3 Department of Radiation Oncology, Houston Methodist Hospital, Cancer Center and Research Institute, Houston, TX 77030, USA.
authors.forename: Jorge
authors.initials: J
authors.lastname: Quesada
authors.affiliation: 1 Department of Radiation Oncology, Baylor College of Medicine, Houston, TX, USA ; 2 Division of Oncology, Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA ; 3 Department of Radiation Oncology, Houston Methodist Hospital, Cancer Center and Research Institute, Houston, TX 77030, USA.
authors.forename: Bin S
authors.initials: BS
authors.lastname: Teh
keywords: Liver regeneration (LR); cirrhosis; metastasis; radiation; stereotactic; stereotactic body radiation therapy (SBRT)
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