title: Endogenous opioids and feeding behavior: A decade of further progress (2004-2014). A Festschrift to Dr. Abba Kastin.
abstract: Functional elucidation of the endogenous opioid system temporally paralleled the creation and growth of the journal, Peptides, under the leadership of its founding editor, Dr. Abba Kastin. He was prescient in publishing annual and uninterrupted reviews on Endogenous Opiates and Behavior that served as a microcosm for the journal under his stewardship. This author published a 2004 review, "Endogenous opioids and feeding behavior: a thirty-year historical perspective", summarizing research in this field between 1974 and 2003. The present review "closes the circle" by reviewing the last 10 years (2004-2014) of research examining the role of endogenous opioids and feeding behavior. The review summarizes effects upon ingestive behavior following administration of opioid receptor agonists, in opioid receptor knockout animals, following administration of general opioid receptor antagonists, following administration of selective mu, delta, kappa and ORL-1 receptor antagonists, and evaluating opioid peptide and opioid receptor changes in different food intake models.
authors.affiliation: Department of Psychology and Behavioral and Cognitive Neuroscience Doctoral Program Cluster, Queens College, City University of New York, Flushing, NY 11367, United States. Electronic address: richard.bodnar@qc.cuny.edu.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Bodnar
mesh_terms: D000818:Animals; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D009292:Narcotic Antagonists / Q000494:pharmacology; D018847:Opioid Peptides / Q000266:history / Q000378:metabolism*; D011957:Receptors, Opioid / Q000266:history / Q000378:metabolism*
chemical_list: D009292:Narcotic Antagonists; D018847:Opioid Peptides; D011957:Receptors, Opioid
keywords: Delta opioid receptor; Food intake; Kappa opioid receptor; Mu opioid receptor; ORL-1 opioid receptor