title: Hypotonic hyporesponsive episode and the 13-valent pneumococcal vaccine.
abstract: Hypotensive-hyporesponsive episodes are rare events after immunizations performed for diphtheria, tetanus, Haemophilus influenzae type b and hepatitis B virus vaccines, but most of the reported episodes have been associated with pertussis-containing vaccines. We report the case of a 3-month-old girl, previously healthy otherwise, presenting with the unusual event of a hypotonic-hyporesponsive episode after vaccination with the 13-valent pneumococcal vaccine. Diagnosis was established after a thorough evaluation of the patient and by exclusion of other clinical conditions.
authors.affiliation: 1st Department of Pediatrics, P. & A. Kyriakou Children's Hospital, Athens, Greece. labfotis@hotmail.com.
authors.forename: Lampros
authors.initials: L
authors.lastname: Fotis
authors.forename: Andriani
authors.initials: A
authors.lastname: Vazeou
authors.forename: Maria
authors.initials: M
authors.lastname: Xatzipsalti
authors.forename: Lela
authors.initials: L
authors.lastname: Stamoyannou
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D009123:Muscle Hypotonia / Q000139:chemically induced*; D011008:Pneumococcal Infections / Q000517:prevention & control; D022242:Pneumococcal Vaccines / Q000009:adverse effects*; D014611:Vaccination / Q000009:adverse effects*; D018074:Vaccines, Conjugate
chemical_list: C538862:13-valent pneumococcal vaccine; D022242:Pneumococcal Vaccines; D018074:Vaccines, Conjugate