title: Vemurafenib/dabrafenib and trametinib.
authors.affiliation: Centre for Human Drug Research, Leiden, the Netherlands.|Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Robert
authors.initials: R
authors.lastname: Rissmann
authors.affiliation: Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Marleen H M
authors.initials: MH
authors.lastname: Hessel
authors.affiliation: Centre for Human Drug Research, Leiden, the Netherlands.|Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Adam F
authors.identifier: http://orcid.org/0000-0001-7452-6222
authors.initials: AF
authors.lastname: Cohen
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000009:adverse effects; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D007211:Indoles / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D020935:MAP Kinase Signaling System / Q000187:drug effects*; D008545:Melanoma / Q000188:drug therapy*; D010091:Oximes / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D011728:Pyridones / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D011744:Pyrimidinones / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D013449:Sulfonamides / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D000077484:Vemurafenib
chemical_list: D000970:Antineoplastic Agents; D007093:Imidazoles; D007211:Indoles; D010091:Oximes; D011728:Pyridones; D011744:Pyrimidinones; D013449:Sulfonamides; D000077484:Vemurafenib; C560077:trametinib; C561627:dabrafenib
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