title: Mammary-like adenocarcinoma of the vulva associated to Paget's disease: a case report.
abstract: Mammary-like adenocarcinoma of the vulva associated to Paget's disease is exceedingly rare. So, it is very important to perform all the pathological and immunohistochemical investigations to achieve differential diagnosis from both a metastatic lesion from an orthotopic breast cancer and a vulvar adnexal tumor. This report describes a case of vulvar Paget's disease associated with underlying mammary-like adenocarcinoma diagnosed in the Department of Obstetrics and Gynecology of Farhat Hached university hospital of Sousse in Tunisia. We also review previously reported cases of primary breast-like carcinoma of the vulva with or without Paget's disease.
authors.affiliation: Department of Gynecology and obstetrics, Farhat Hached University Hospital, Sousse, Tunisia ; Research laboratory in quality of Maternal Health Care Tunisia.
authors.forename: Sawsen
authors.initials: S
authors.lastname: Meddeb
authors.affiliation: Department of Gynecology and obstetrics, Farhat Hached University Hospital, Sousse, Tunisia.
authors.forename: Mohamed Salah
authors.initials: MS
authors.lastname: Rhim
authors.affiliation: Department of Pathology, Farhat Hached University Hospital, Sousse, Tunisia.
authors.forename: Sarra
authors.initials: S
authors.lastname: Mestiri
authors.affiliation: Department of Gynecology and obstetrics, Farhat Hached University Hospital, Sousse, Tunisia.
authors.forename: Mouna
authors.initials: M
authors.lastname: Kouira
authors.affiliation: Department of Gynecology and obstetrics, Farhat Hached University Hospital, Sousse, Tunisia.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Bibi
authors.affiliation: Department of Gynecology and obstetrics, Farhat Hached University Hospital, Sousse, Tunisia.
authors.forename: Hedi
authors.initials: H
authors.lastname: Khairi
authors.affiliation: Department of Pathology, Farhat Hached University Hospital, Sousse, Tunisia.
authors.forename: Mohamed Tahar
authors.initials: MT
authors.lastname: Yacoubi
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D000328:Adult; D005260:Female; D006801:Humans; D042361:Mammary Glands, Human / Q000473:pathology*; D010145:Paget Disease, Extramammary / Q000175:diagnosis / Q000473:pathology*; D014416:Tunisia; D014846:Vulvar Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*
keywords: Mammary-like adenocarcinoma; Paget′s disease; vulva
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