title: The anticancer and antiobesity effects of Mediterranean diet.
abstract: Cancers have been the leading cause of death worldwide and the prevalence of obesity is also increasing in these few decades. Interestingly, there is a direct association between cancer and obesity. Each year, more than 90,000 cancer deaths are caused by obesity or overweight. The dietary pattern in Crete, referred as the traditional Mediterranean diet, is believed to confer Crete people the low mortality rates from cancers. Nevertheless, the antiobesity effect of the Mediterranean diet is less studied. Given the causal relationship between obesity and cancer, the antiobesity effect of traditional Mediterranean diet might contribute to its anticancer effects. In this regard, we will critically review the anticancer and antiobesity effects of this diet and its dietary factors. The possible mechanisms underlying these effects will also be discussed.
authors.affiliation: a Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University , Kowloon Tong , Hong Kong , China.
authors.forename: Hiu Yee
authors.initials: HY
authors.lastname: Kwan
authors.affiliation: a Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University , Kowloon Tong , Hong Kong , China.
authors.forename: Xiaojuan
authors.initials: X
authors.lastname: Chao
authors.affiliation: a Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University , Kowloon Tong , Hong Kong , China.
authors.forename: Tao
authors.initials: T
authors.lastname: Su
authors.affiliation: a Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University , Kowloon Tong , Hong Kong , China.
authors.forename: Xiuqiong
authors.initials: X
authors.lastname: Fu
authors.affiliation: a Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University , Kowloon Tong , Hong Kong , China.
authors.forename: Anfernee Kai Wing
authors.initials: AK
authors.lastname: Tse
authors.affiliation: a Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University , Kowloon Tong , Hong Kong , China.
authors.forename: Wang Fun
authors.initials: WF
authors.lastname: Fong
authors.affiliation: a Centre for Cancer and Inflammation Research, School of Chinese Medicine, Hong Kong Baptist University , Kowloon Tong , Hong Kong , China.
authors.forename: Zhi-Ling
authors.initials: ZL
authors.lastname: Yu
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000032:analysis / Q000627:therapeutic use; D019440:Anti-Obesity Agents / Q000032:analysis / Q000627:therapeutic use; D016588:Anticarcinogenic Agents / Q000032:analysis / Q000627:therapeutic use; D000072001:Diet, Healthy; D038441:Diet, Mediterranean; D019317:Evidence-Based Medicine; D063427:Food Quality; D006115:Greece / Q000453:epidemiology; D006801:Humans; D009369:Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000276:immunology / Q000517:prevention & control*; D009765:Obesity / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology / Q000517:prevention & control*; D000069463:Olive Oil / Q000737:chemistry / Q000592:standards / Q000627:therapeutic use; D050177:Overweight / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology / Q000517:prevention & control*; D010349:Patient Compliance; D012306:Risk; D014920:Wine / Q000009:adverse effects / Q000032:analysis
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D019440:Anti-Obesity Agents; D016588:Anticarcinogenic Agents; D000069463:Olive Oil
keywords: Mediterranean diet; cancer; nutrition; obesity; olive oil; polyphenols