title: Failure of artelon interposition arthroplasty after partial trapeziectomy: a case report with histologic and immunohistochemical analysis.
abstract: Artelon is a degradable biomaterial used for the treatment of osteoarthritis in the carpometacarpal joint of the thumb. The device reportedly works through 2 modes of action-stabilization of the carpometacarpal joint by augmentation of the joint capsule and by formation of a new articular surface at the trapeziometacarpal interface. We present a patient with late failure of arthroscopic hemitrapeziectomy and Artelon interposition that required surgical excision of the Artelon implant and trapeziectomy 4 years postoperatively. Gross and histologic evaluation of the explanted Artelon implant and remaining trapezium revealed lack of articular resurfacing by hyaline ingrowth.
authors.forename: Yi-Chao
authors.initials: YC
authors.lastname: Huang
authors.forename: Leila
authors.initials: L
authors.lastname: Jazayeri
authors.forename: Wei
authors.initials: W
authors.lastname: Le
authors.affiliation: Department of Orthopaedic Surgery, Stanford University Medical Center, Stanford, CA. jyao@stanford.edu.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Yao
mesh_terms: D020341:Absorbable Implants; D001178:Arthroplasty / Q000379:methods*; D001672:Biocompatible Materials; D052737:Carpometacarpal Joints / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000473:pathology / Q000601:surgery; D011140:Polyurethanes; D013933:Thumb / Q000473:pathology / Q000601:surgery; D051222:Trapezium Bone / Q000473:pathology / Q000601:surgery*
chemical_list: D001672:Biocompatible Materials; D011140:Polyurethanes; C044690:polyetherurethane urea