title: [Molecular-genetic analysis of the genomes of porcine reproductive and respiratory syndrome virus and porcine circovirus type 2 circulating in the area of Russian Federation].
abstract: The molecular genetic analysis of the genomes of the virus of porcine reproductive respiratory syndrome (VPRRS) and porcine circovirus type 2 (PCV-2) circulating in the area of the Russian Federation was discussed. The results of this work showed the circulation of the strains of the European genotype VPRRS similar to those found in France and Denmark from 1998 to 2001. The homology of the fragment of one of the genes between the Russian isolates and the vaccine strain Porcilis PRRS (Intervet) was found. It requires further study. The strains representing the North American genotype VPRRS were not found. The PCV-2 genomes fall into three separate goups. One (genotype 2b) is formed by isolates in Malaysia, Brazil, Switzerland, China, Slovakia, UK, USA, isolated during the period from 2004 to the present time. The second group consists of sequences of the viruses isolated in 2000-2012 in Canada, the U.S., China, and South Korea (genotype 2a). The third group is formed by highly pathogenic isolates in 2013 from China (highly pathogenic genotype 2c). The circulation of all three known genotypes of PCV-2: 2a, 2b, and 2c in Russian Federation was demonstrated.
authors.forename: A D
authors.initials: AD
authors.lastname: Bulgakov
authors.forename: T V
authors.initials: TV
authors.lastname: Grebennikova
authors.forename: A G
authors.initials: AG
authors.lastname: Iuzhakov
authors.forename: T I
authors.initials: TI
authors.lastname: Aliper
authors.forename: E A
authors.initials: EA
authors.lastname: Nepoklonov
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017925:Circovirus / Q000235:genetics* / Q000472:pathogenicity; D016679:Genome, Viral; D005838:Genotype; D010802:Phylogeny; D019318:Porcine Reproductive and Respiratory Syndrome / Q000235:genetics* / Q000821:virology; D019316:Porcine respiratory and reproductive syndrome virus / Q000235:genetics* / Q000472:pathogenicity; D012426:Russia; D013552:Swine