title: Outcomes of knee disarticulation and the influence of surgical techniques in dysvascular patients: A systematic review.
abstract: BACKGROUND
  Dysvascularity is the main cause of lower limb amputations in Scotland, and there is an insignificant proportion (1.7%) of knee disarticulations, despite the benefits of amputation.
  
  
  OBJECTIVE
  The outcomes of knee disarticulation and its associated surgical techniques will be evaluated based on healing, reamputations, functional outcomes, prosthetic ambulation and gait biomechanics to determine whether a greater rate of knee disarticulations can be justified among dysvascular patients.
  
  
  METHODS
  Systematic review.
  
  
  METHODS
  Key electronic databases were searched for the relevant literature based on a pre-specified eligibility criterion.
  
  
  RESULTS
  The 17 articles included in this review were appraised for their quality, and key findings are extracted.
  
  
  CONCLUSIONS
  Healing rates are favourable, but there is a need for appropriate amputation level selection to prevent reamputations. Knee disarticulation patients have better maintenance of independent living status than transfemoral patients, but overall prosthetic ambulation rates are inconsistent. In terms of gait biomechanics of knee disarticulation, there are some positive indications, but the evidence is insubstantial. A stronger body of evidence is required in this subject field, and recommendations are made for future research - Scottish Intercollegiate Guidelines Network Grade of Recommendation: C.
  
  
  CONCLUSIONS
  This review aims to inform the multidisciplinary teams involved in the rehabilitation of dysvascular amputees about evidence-based outcomes following knee disarticulation. This knowledge will be beneficial when formulating treatment pathways for this vulnerable population group.
authors.affiliation: Department of Biomedical Engineering, National Centre for Prosthetics and Orthotics, University of Strathclyde, Glasgow, UK.
authors.forename: Tsurayuki
authors.initials: T
authors.lastname: Murakami
authors.affiliation: Department of Biomedical Engineering, National Centre for Prosthetics and Orthotics, University of Strathclyde, Glasgow, UK kevin.d.murray@strath.ac.uk.
authors.forename: Kevin
authors.initials: K
authors.lastname: Murray
mesh_terms: D001186:Artificial Limbs; D004188:Disarticulation; D006801:Humans; D007719:Knee Joint; D016491:Peripheral Vascular Diseases / Q000601:surgery*; D016896:Treatment Outcome
keywords: Gritti–Stokes; Knee disarticulation; Mazet; amputee; dysvascular; prosthesis; rehabilitation; through-knee