title: Ovarian tuberculosis masquerading as ovarian cancer in HIV infected patient: a plea to avoid unnecessary surgery.
abstract: Female patients who present with adnexial mass and weight loss should not be presumed to have ovarian carcinoma until after extensive investigation. This is to avoid the mistake of radical surgery with its attendant morbidity and mortality. An important disease to consider in our environment is ovarian TB that respond well to medication. A 35 year old HIV-1 positive house wife presented with fever, persistent vomiting, progressive weight loss, vague abdominal pain and swelling. Patient occasionally ingest unpasteurized milk since childhood but had no sustained contact with adult with chronic cough. She had no menstrual abnormality. Imaging studies revealed right ovarian mass measuring 11.8 cm x 10 cm. Right ovarian malignancy was highly suspected, for which she underwent exploratory laporotomy. Histopathology result was consistent with tuberculous granuloma. Chest radiograph was normal. Her CD4 count was 541 cells/ul. Patient was commenced on anti tuberculotic therapy based on the Nigerian National TB control and she responded well. Tuberculosis of the ovary can masquerade as ovarian cancer, especially among HIV patients in regions where TB-HIV co infections is endemic, it should be ruled out before performing extended surgery.
authors.affiliation: Department of Medicine, College of Medical Sciences, University of Maiduguri, PMB 1069, Maiduguri, Nigeria.
authors.forename: Ballah Akawu
authors.initials: BA
authors.lastname: Denue
authors.affiliation: Department of Obstetrics and Gynaecology, College of Medical Sciences, University of Maiduguri, PMB 1069, Maiduguri, Nigeria.
authors.forename: Salisu Aliyu
authors.initials: SA
authors.lastname: Kwayabura
authors.affiliation: Department of Histopathology, College of Medical Sciences, University of Maiduguri, PMB 1069, Maiduguri, Nigeria.
authors.forename: Haruna Asura
authors.initials: HA
authors.lastname: Ngadda
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D010049:Ovarian Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D010051:Ovarian Neoplasms / Q000175:diagnosis*; D014384:Tuberculosis, Female Genital / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents
keywords: HIV-TB co infection; Ovarian TB; ovarian cancer
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