title: Visible-light-mediated radical aryldifluoroacetylation of alkynes with ethyl bromodifluoroacetate for the synthesis of 3-difluoroacetylated coumarins.
abstract: A mild and efficient method for the synthesis of 3-difluoroacetylated coumarins through visible-light-promoted aryldifluoroacetylation of alkynes with ethyl bromodifluoroacetate has been developed. The reaction allows the direct formation of Csp(2)-CF2COOEt and C-C bonds via a proposed tandem radical cyclization process.
authors.affiliation: †College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang 471022, People's Republic of China.
authors.forename: Weijun
authors.initials: W
authors.lastname: Fu
authors.affiliation: †College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang 471022, People's Republic of China.
authors.forename: Mei
authors.initials: M
authors.lastname: Zhu
authors.affiliation: ‡The College of Chemistry and Environmental Science, Guizhou Minzu Univeristy, Guiyang 550025, People's Republic of China.
authors.forename: Guanglong
authors.initials: G
authors.lastname: Zou
authors.affiliation: †College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang 471022, People's Republic of China.
authors.forename: Chen
authors.initials: C
authors.lastname: Xu
authors.affiliation: †College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang 471022, People's Republic of China.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Wang
authors.affiliation: †College of Chemistry and Chemical Engineering, Luoyang Normal University, Luoyang 471022, People's Republic of China.
authors.forename: Baoming
authors.initials: B
authors.lastname: Ji
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry; D005463:Fluoroacetates / Q000737:chemistry*; D005609:Free Radicals / Q000737:chemistry; D008027:Light; D015394:Molecular Structure
chemical_list: D000480:Alkynes; D003374:Coumarins; D005463:Fluoroacetates; D005609:Free Radicals