title: An Implantable RFID Sensor Tag toward Continuous Glucose Monitoring.
abstract: This paper presents a wirelessly powered implantable electrochemical sensor tag for continuous blood glucose monitoring. The system is remotely powered by a 13.56-MHz inductive link and utilizes an ISO 15693 radio frequency identification (RFID) standard for communication. This paper provides reliable and accurate measurement for changing glucose level. The sensor tag employs a long-term glucose sensor, a winding ferrite antenna, an RFID front-end, a potentiostat, a 10-bit sigma-delta analog to digital converter, an on-chip temperature sensor, and a digital baseband for protocol processing and control. A high-frequency external reader is used to power, command, and configure the sensor tag. The only off-chip support circuitry required is a tuned antenna and a glucose microsensor. The integrated chip fabricated in SMIC 0.13-μm CMOS process occupies an area of 1.2 mm ×2 mm and consumes 50 μW. The power sensitivity of the whole system is -4 dBm. The sensor tag achieves a measured glucose range of 0-30 mM with a sensitivity of 0.75 nA/mM.
authors.forename: Zhibin
authors.initials: Z
authors.lastname: Xiao
authors.forename: Xi
authors.initials: X
authors.lastname: Tan
authors.forename: Xianliang
authors.initials: X
authors.lastname: Chen
authors.forename: Sizheng
authors.initials: S
authors.lastname: Chen
authors.forename: Zijian
authors.initials: Z
authors.lastname: Zhang
authors.forename: Hualei
authors.initials: H
authors.lastname: Zhang
authors.forename: Junyu
authors.initials: J
authors.lastname: Wang
authors.forename: Yue
authors.initials: Y
authors.lastname: Huang
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
authors.forename: Lirong
authors.initials: L
authors.lastname: Zheng
authors.forename: Hao
authors.initials: H
authors.lastname: Min
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D045604:Extracellular Fluid / Q000737:chemistry; D008297:Male; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D019736:Prostheses and Implants; D011474:Prosthesis Design; D057233:Radio Frequency Identification Device; D051381:Rats; D017208:Rats, Wistar; D012680:Sensitivity and Specificity; D059015:Wireless Technology / Q000295:instrumentation*
chemical_list: D001786:Blood Glucose