title: Predictive factors of the outcome and intraventricular rupture of brain abscess.
abstract: OBJECTIVE
  To identify the significant factors predicting afavorable outcome and to study clinical characteristics and identify the factors predicted by intraventricular rupture of brain abscess (IVROBA).
  
  
  METHODS
  In the retrospective study, the computer-based medical records of patients of a tertiary care hospital between 1999 and 2013 were reviewed. Univariate and multivariate analyses were used to determine the significant factors predicting the outcomes and IVROBA.
  
  
  RESULTS
  One hundred fourteen patients with brain abscesses were enrolled. The predictivefactor of a favorable outcome was Glasgow Coma Scale (GCS) score 13 to 15 (OR 14.64; 95% CI 2.70-79.34; p = 0.02). Conversely, the factors associated with an unfavorable outcome were fungal brain abscess (OR 40.81; 95% CI 3.57-466.49; p = 0.003) and IVROBA (OR 5.50; 95% CI 1.34-22.49; p = 0.017). Moreover greater distance of the brain abscess from the ventricle decreased the IVROBA (OR 0.62; 95% CI 0.45-0.87; p = 0.005). Abscesses with intraventricular rupture that were at less than 7 mm of a ventricle (p < 0.000) were likely to IVROBA.
  
  
  CONCLUSIONS
  The outcome of a brain abscess depends on good clinical status, pathogens, and fatal complication of lVROBA. If poor prognostic factors exist, then better surgical option can be selected.
authors.forename: Thara
authors.initials: T
authors.lastname: Tunthanathip
authors.forename: Kanet
authors.initials: K
authors.lastname: Kanjanapradit
authors.forename: Sakchai
authors.initials: S
authors.lastname: Sae-Heng
authors.forename: Thakul
authors.initials: T
authors.lastname: Oearsakul
authors.forename: Ittichai
authors.initials: I
authors.lastname: Sakarunchai
mesh_terms: D000368:Aged; D001922:Brain Abscess / Q000382:microbiology / Q000473:pathology* / Q000628:therapy; D002552:Cerebral Ventricles / Q000382:microbiology / Q000473:pathology; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012422:Rupture, Spontaneous / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D016896:Treatment Outcome