title: [Autoimmune hepatitis preceded by hepatitis A].
abstract: Autoimmune hepatitis is characterized by unresolving inflammation and fibrosis of the liver, which untreated may lead to cirrhosis. The pathogenesis remains unclear and reflects a complex interaction between autoantigens, genetic predisposition, triggering factors and immune regulation. In rare cases, acute hepatitis A has been suspected as a triggering factor. We describe a case of a 66-year-old woman who two months after a resolving acute hepatitis A presented with fatigue, pale stools and elevated levels of transaminases. A liver biopsy showed histological changes compatible with autoimmune hepatitis.
authors.affiliation: Medicinsk Gastroenterologisk Afdeling, Aalborg Universitetshospital, Mølleparkvej 4, 9000 Aalborg. anne.grave@studmed.au.dk.
authors.forename: Anne
authors.initials: A
authors.lastname: Grave
authors.forename: Jacob
authors.initials: J
authors.lastname: Juel
authors.forename: Mogens
authors.initials: M
authors.lastname: Vyberg
authors.forename: Søren Schou
authors.initials: SS
authors.lastname: Olesen
authors.forename: Jesper Bach
authors.initials: JB
authors.lastname: Hansen
mesh_terms: D000368:Aged; D005260:Female; D006506:Hepatitis A / Q000150:complications*; D019693:Hepatitis, Autoimmune / Q000209:etiology*; D006801:Humans