title: Taurine Depletion Decreases GRP78 Expression and Downregulates Perk-Dependent Activation of the Unfolded Protein Response.
authors.affiliation: Department of Pharmacology, College of Medicine, University of South Alabama, Mobile, AL, USA.
authors.forename: Chian Ju
authors.initials: CJ
authors.lastname: Jong
authors.forename: Takashi
authors.initials: T
authors.lastname: Ito
authors.forename: Junichi
authors.initials: J
authors.lastname: Azuma
authors.forename: Stephen
authors.initials: S
authors.lastname: Schaffer
mesh_terms: D000375:Aging / Q000502:physiology; D000818:Animals; D015536:Down-Regulation / Q000235:genetics; D000091342:Endoplasmic Reticulum Chaperone BiP; D015870:Gene Expression / Q000187:drug effects; D006360:Heat-Shock Proteins / Q000235:genetics* / Q000378:metabolism; D008562:Membrane Glycoproteins / Q000235:genetics*; D026901:Membrane Transport Proteins / Q000235:genetics*; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D015398:Signal Transduction / Q000187:drug effects / Q000235:genetics; D013654:Taurine / Q000172:deficiency* / Q000494:pharmacology; D056811:Unfolded Protein Response / Q000187:drug effects / Q000235:genetics; D019892:eIF-2 Kinase / Q000502:physiology*; D000099247:Taurine Transporters
chemical_list: D000091342:Endoplasmic Reticulum Chaperone BiP; D006360:Heat-Shock Proteins; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D013654:Taurine; D019892:eIF-2 Kinase; D000099247:Taurine Transporters; C000717248:Hspa5 protein, mouse