title: Selective myelosuppression following yellow phosphorus ingestion.
abstract: Toxicity from accidental and intentional ingestion of yellow phosphorus, ubiquitously present in fireworks and rodenticides, has recently become more frequent. Gastrointestinal, renal, neurologic, and cardiovascular manifestations are common, with mortality of 23 per cent to 73 per cent. Reports of haematological abnormalities are rare. We report only the second case of severe neutropenia secondary to selective myelosuppression in a 14-year-old girl following intentional ingestion of yellow phosphorus. Leucocyte counts recovered spontaneously without further complications. Our case indicates that, besides hepatic and renal function monitoring, physicians should meticulously monitor blood counts in such cases for early detection of marrow suppression. Further studies are required to elucidate the complex mechanisms and significance of this unusual toxicity of yellow phosphorus.
authors.affiliation: Department of General Medicine, Pondicherry Institute of Medical Sciences, Pondicherry, India.
authors.forename: Aneesh
authors.initials: A
authors.lastname: Basheer
authors.affiliation: Department of General Medicine, Pondicherry Institute of Medical Sciences, Pondicherry, India.
authors.forename: Sudhagar
authors.initials: S
authors.lastname: Mookkappan
authors.affiliation: Department of Pathology, Pondicherry Institute of Medical Sciences, Pondicherry, India.
authors.forename: Somanath
authors.initials: S
authors.lastname: Padhi
authors.affiliation: Department of General Medicine, Pondicherry Institute of Medical Sciences, Pondicherry, India.
authors.forename: Nayyar
authors.initials: N
authors.lastname: Iqbal
keywords: myelosuppression; neutropenia; yellow phosphorus
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