title: Stickler syndrome. Epidemiology of retinal detachment.
abstract: OBJECTIVE
  A review was performed on all patients with Stickler syndrome that had been treated in our Centre since it was diagnosed, in order to evaluate the risk of suffering a retinal detachment (RD).
  
  
  METHODS
  A total of 14 patients, diagnosed by clinical criteria, were included. The following variables were evaluated: age, gender, ocular background, follow-up, initial and final visual acuity (VA), optical prescription, prophylactic treatment, surgery and techniques performed. The risk age to suffer a RD, as well as cataracts, was determined by using the Kaplan-Meier survival curve analysis.
  
  
  RESULTS
  From a total of 5 men and 9 women, the median initial VA was 0.35, which was the same as the final VA. The median optical prescription was -9.5 D myopia. The median of follow-up was 7 years. Ocular background was 4 RD cases and 2 Lasik surgeries. The operations performed were 8 RD, 12 cataract, 2 glaucoma, 2 macular hole, and one endotropia. The median age of RD was 20 years and cataract 34 years. As regards surgical tecnique, 4 scleral buckle cases, and 4 scleral buckle+pars plana vitrectomy cases were formed. The prophylactic treatments performed were: one scleral buckle case, 4 endolaser photocoagulation, and one cryotherapy. Two of which presented with RD.
  
  
  CONCLUSIONS
  In the series presented, retinal detachment in Stickler syndrome mainly occurs in the second decade of life, with cataracts mainly developing in the fourth decade.
authors.affiliation: Centro de Oftalmología Barraquer, Barcelona, España. Electronic address: ferranvilaplanamira@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: Vilaplana
authors.affiliation: Centro de Oftalmología Barraquer, Barcelona, España.
authors.forename: S J
authors.initials: SJ
authors.lastname: Muiños
authors.affiliation: Centro de Oftalmología Barraquer, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Nadal
authors.affiliation: Centro de Oftalmología Barraquer, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Elizalde
authors.affiliation: Consulting Service on Methodology for Miomedical Research, IMIM, Barcelona, España.
authors.forename: S
authors.initials: S
authors.lastname: Mojal
mesh_terms: D000293:Adolescent; D000328:Adult; D001168:Arthritis / Q000453:epidemiology* / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D003240:Connective Tissue Diseases / Q000453:epidemiology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006319:Hearing Loss, Sensorineural / Q000453:epidemiology* / Q000601:surgery; D006801:Humans; D008297:Male; D013508:Ophthalmologic Surgical Procedures / Q000706:statistics & numerical data; D012163:Retinal Detachment / Q000453:epidemiology* / Q000601:surgery; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
keywords: Agujero macular; Cataract; Catarata; Desprendimiento de retina; Glaucoma; Macular hole; Retinal detachment; Sickler syndrome; Síndrome de Stickler; Vitrectomy; Vitrectomía