title: Adipose stem cells: biology, safety, regulation, and regenerative potential.
abstract: This article discusses adipose-derived stem cell (ASC) biology, describes the current knowledge in the literature for the safety and regulation of ASCs, and provides a brief overview of the regenerative potential of ASCs. It is not an exhaustive listing of all available clinical studies or every study applying ASCs in tissue engineering and regenerative medicine, but is an objective commentary of these topics.
authors.affiliation: Department of Bioengineering, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
authors.forename: Danielle M
authors.initials: DM
authors.lastname: Minteer
authors.affiliation: Department of Bioengineering, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA; Department of Plastic Surgery, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15213, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, 450 Technology Drive, Pittsburgh, PA 15213, USA.
authors.forename: Kacey G
authors.initials: KG
authors.lastname: Marra
authors.affiliation: Department of Bioengineering, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA; Department of Plastic Surgery, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15213, USA; McGowan Institute for Regenerative Medicine, University of Pittsburgh, 450 Technology Drive, Pittsburgh, PA 15213, USA. Electronic address: rubipj@upmc.edu.
authors.forename: J Peter
authors.initials: JP
authors.lastname: Rubin
mesh_terms: D017667:Adipocytes / Q000166:cytology / Q000637:transplantation; D000273:Adipose Tissue / Q000166:cytology* / Q000637:transplantation; D006801:Humans; D044968:Regenerative Medicine / Q000379:methods*; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology*; D023822:Tissue Engineering / Q000379:methods*
keywords: Adipose; Adipose-derived stem cells; Clinical translation; Mesenchymal stem cells; Regenerative medicine; Stem cell safety; Stromal vascular fraction; Tissue engineering