title: The buffalo co-infection conundrum.
abstract: Parasitic worms modulate host immunity, affecting co-infection with Mycobacterium bovis (BTB). Ezenwa and Jolles suggested that anthelmintic treatment reduced BTB-induced mortality, but increased BTB spread. Reduced mortality should be weighed against the risk of increasing pathogen spread when adopting this strategy for human treatment of Mycobacterium tuberculosis, BTB, and HIV.
authors.affiliation: Animal and Poultry Science, 127 Rabie Saunders Building, SAEES, University of KwaZulu-Natal, South Africa.
authors.forename: Sylvester W
authors.initials: SW
authors.lastname: Fomum
authors.affiliation: Animal and Poultry Science, 127 Rabie Saunders Building, SAEES, University of KwaZulu-Natal, South Africa. Electronic address: NsahlaiI@ukzn.ac.za.
authors.forename: Ignatius V
authors.initials: IV
authors.lastname: Nsahlai
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use*; D003141:Communicable Diseases / Q000401:mortality*; D005260:Female; D056084:Genetic Fitness / Q000187:drug effects*; D006374:Helminthiasis, Animal / Q000188:drug therapy*; D054884:Host-Pathogen Interactions / Q000187:drug effects*; D009163:Mycobacterium bovis / Q000187:drug effects*; D014380:Tuberculosis, Bovine / Q000401:mortality*
chemical_list: D000969:Antinematodal Agents
keywords: anthelmintic treatment; bovine tuberculosis; co-infection; infectious diseases