title: [Effectiveness of anti-tumor necrosis factor-α therapy in Crohn's disease with abscesses around the sigmoid colon: a case report].
abstract: We report the case of a man in his 50s who was diagnosed with Crohn's colitis in his 30s and who presented with post-prandial lower abdominal pain in January, 20XX. Colonoscopy and abdominal contrast-enhanced computed tomography revealed abscesses around the sigmoid colon. Although his response to antibiotics was poor, treatment with a combination of antibiotics and adalimumab resolved the abscesses. Nine months later, however, the abscesses around the sigmoid colon recurred. Treatment comprising bowel rest and antibiotics led to immediate improvement of the symptoms. We report a case of effective anti-tumor necrosis factor-α therapy in Crohn's colitis with abscesses around the sigmoid colon.
authors.affiliation: Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine.
authors.forename: Kengo
authors.initials: K
authors.lastname: Nagai
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Shinzaki
authors.forename: Motohiko
authors.initials: M
authors.lastname: Kato
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hiyama
authors.forename: Takayuki
authors.initials: T
authors.lastname: Yakushijin
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Nishida
authors.forename: Hideki
authors.initials: H
authors.lastname: Iijima
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Ookawa
authors.forename: Masahiko
authors.initials: M
authors.lastname: Tsujii
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Takehara
mesh_terms: D018784:Abdominal Abscess / Q000150:complications / Q000188:drug therapy*; D000068879:Adalimumab / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D003424:Crohn Disease / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012810:Sigmoid Diseases / Q000150:complications / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000068879:Adalimumab