title: Delayed presentation of nitroprusside-induced cyanide toxicity.
abstract: Cyanide toxicity is a rare complication of sodium nitroprusside that can be difficult to diagnose in critically ill patients. We describe a case of cyanide toxicity after cardiac surgery that presented as lactic acidosis after discontinuation of nitroprusside.
authors.affiliation: Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: udehc@ccf.org.
authors.forename: Chiedozie I
authors.initials: CI
authors.lastname: Udeh
authors.affiliation: Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Michael
authors.initials: M
authors.lastname: Ting
authors.affiliation: Department of Pharmacy, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Matthew
authors.initials: M
authors.lastname: Arango
authors.affiliation: Department of Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Mick
mesh_terms: D000140:Acidosis, Lactic / Q000175:diagnosis* / Q000209:etiology; D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D000368:Aged; D006348:Cardiac Surgical Procedures / Q000009:adverse effects* / Q000379:methods; D016638:Critical Illness; D003486:Cyanides / Q000378:metabolism / Q000506:poisoning*; D057210:Delayed Diagnosis; D003937:Diagnosis, Differential; D004305:Dose-Response Relationship, Drug; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007262:Infusions, Intravenous; D009599:Nitroprusside / Q000008:administration & dosage / Q000009:adverse effects*; D006435:Renal Dialysis; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D003486:Cyanides; D009599:Nitroprusside