title: Group Exchange between Ketones and Carboxylic Acids through Directing Group Assisted Rh-Catalyzed Reorganization of Carbon Skeletons.
abstract: The Rh(I)-catalyzed direct reorganization of organic frameworks and group exchanges between carboxylic acids and aryl ketones was developed with the assistance of directing group. Biaryls, alkenylarenes, and alkylarenes were produced in high efficiency from aryl ketones and the corresponding carboxylic acids by releasing the other molecule of carboxylic acids and carbon monoxide. A wide range of functional groups were well compatible. The exchanges between two partners were proposed to take place on the Rh-(III) center of key intermediates, supported by experimental mechanistic studies and computational calculations. The transformation unveiled the new catalytic pathway of the group transfer of two organic molecules.
authors.affiliation: †Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, Sichuan 610041, China.|‡Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.
authors.forename: Zhi-Quan
authors.initials: ZQ
authors.lastname: Lei
authors.affiliation: ‡Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Pan
authors.affiliation: ‡Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.
authors.forename: Hu
authors.initials: H
authors.lastname: Li
authors.affiliation: ‡Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.affiliation: ‡Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.
authors.forename: Xi-Sha
authors.initials: XS
authors.lastname: Zhang
authors.affiliation: ‡Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.
authors.forename: Kang
authors.initials: K
authors.lastname: Chen
authors.affiliation: ‡Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.affiliation: §State Key Laboratory of Organometallic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
authors.forename: Yu-Xue
authors.initials: YX
authors.lastname: Li
authors.affiliation: †Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, Sichuan 610041, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Sun
authors.affiliation: ‡Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.|§State Key Laboratory of Organometallic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China.
authors.forename: Zhang-Jie
authors.initials: ZJ
authors.lastname: Shi
mesh_terms: D002244:Carbon / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D007659:Ketones; D009942:Organometallic Compounds; D002244:Carbon; D012238:Rhodium