title: Ligand-enabled cross-coupling of C(sp(3))-H bonds with arylsilanes.
abstract: Pd(II)-catalyzed cross-coupling of C(sp(3))-H bonds with organosilicon coupling partners has been achieved for the first time. The use of a newly developed quinoline-based ligand is essential for the cross-coupling reactions to proceed.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
authors.forename: Jian
authors.initials: J
authors.lastname: He
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Takise
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Fu
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu
mesh_terms: D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D054879:Halogenation; D006859:Hydrogen / Q000737:chemistry*; D008024:Ligands; D010165:Palladium / Q000737:chemistry; D012821:Silanes / Q000737:chemistry*
chemical_list: D008024:Ligands; D012821:Silanes; D010165:Palladium; D002244:Carbon; D006859:Hydrogen
references.citation: Angew Chem Int Ed Engl. 2014 Jun 23;53(26):6692-5
references.pmid: 24828691
references.citation: Isr J Chem. 2010 Dec;50(5-6):605-616
references.pmid: 21552359
references.citation: J Am Chem Soc. 2004 Apr 21;126(15):4876-82
references.pmid: 15080692
references.citation: J Am Chem Soc. 2010 Apr 7;132(13):4506-7
references.pmid: 20225875
references.citation: J Am Chem Soc. 2012 Nov 14;134(45):18570-2
references.pmid: 23116159
references.citation: Org Lett. 1999 Dec 30;1(13):2137-40
references.pmid: 10836067
references.citation: Acc Chem Res. 2002 Oct;35(10):835-46
references.pmid: 12379136
references.citation: J Am Chem Soc. 2008 Oct 1;130(39):12975-85
references.pmid: 18767837
references.citation: J Am Chem Soc. 2013 Nov 20;135(46):17508-13
references.pmid: 24124892
references.citation: J Am Chem Soc. 2008 Jul 23;130(29):9254-6
references.pmid: 18582040
references.citation: Chemistry. 2011 Jun 14;17(25):6904-8
references.pmid: 21557353
references.citation: J Am Chem Soc. 2011 Nov 16;133(45):18183-93
references.pmid: 21913636
references.citation: Org Lett. 2011 Oct 21;13(20):5413-5
references.pmid: 21939201
references.citation: J Org Chem. 2011 Oct 21;76(20):8543-8
references.pmid: 21910499
references.citation: Angew Chem Int Ed Engl. 2008;47(34):6452-5
references.pmid: 18624318
references.citation: J Am Chem Soc. 2007 May 16;129(19):6066-7
references.pmid: 17455938
references.citation: J Am Chem Soc. 2006 Jan 11;128(1):78-9
references.pmid: 16390130
references.citation: J Am Chem Soc. 2003 May 14;125(19):5616-7
references.pmid: 12733884
references.citation: J Am Chem Soc. 2011 Dec 14;133(49):19598-601
references.pmid: 22059375
references.citation: Org Lett. 2012 Jan 6;14(1):418-21
references.pmid: 22188556
references.citation: Chem Soc Rev. 2011 Oct;40(10):4893-901
references.pmid: 21755089
references.citation: J Am Chem Soc. 2008 Oct 29;130(43):14082-3
references.pmid: 18834125
references.citation: J Am Chem Soc. 2006 Oct 4;128(39):12634-5
references.pmid: 17002342
references.citation: J Am Chem Soc. 2008 Jun 11;130(23):7190-1
references.pmid: 18479089
references.citation: Acc Chem Res. 2003 Apr;36(4):234-45
references.pmid: 12693921
references.citation: Angew Chem Int Ed Engl. 2010 Mar 15;49(12):2202-5
references.pmid: 20187054
references.citation: Chem Asian J. 2013 Sep;8(9):2175-81
references.pmid: 23749384
references.citation: J Am Chem Soc. 2010 Feb 3;132(4):1243-5
references.pmid: 20058920
references.citation: J Am Chem Soc. 2014 Apr 9;136(14):5267-70
references.pmid: 24666182
references.citation: J Am Chem Soc. 2008 Dec 31;130(52):17676-7
references.pmid: 19067651
references.citation: Angew Chem Int Ed Engl. 2011 Jul 18;50(30):6722-37
references.pmid: 21618370
references.citation: Angew Chem Int Ed Engl. 2009;48(29):5355-7
references.pmid: 19533704
references.citation: J Am Chem Soc. 2007 Mar 28;129(12):3510-1
references.pmid: 17335217
references.citation: Acc Chem Res. 2008 Nov 18;41(11):1461-73
references.pmid: 18620434
references.citation: Org Lett. 2009 Aug 6;11(15):3346-9
references.pmid: 19719183
references.citation: Angew Chem Int Ed Engl. 2008;47(26):4882-6
references.pmid: 18484582
references.citation: Angew Chem Int Ed Engl. 2011 Jul 18;50(30):6738-64
references.pmid: 21717531
references.citation: J Am Chem Soc. 2001 Jun 13;123(23):5600-1
references.pmid: 11389653
references.citation: J Am Chem Soc. 2009 Jul 29;131(29):9886-7
references.pmid: 19580277
references.citation: Org Lett. 2010 Jul 16;12(14):3185-7
references.pmid: 20565055
references.citation: Science. 2014 Mar 14;343(6176):1216-20
references.pmid: 24626923
references.citation: J Am Chem Soc. 2013 Mar 6;135(9):3387-90
references.pmid: 23406445