title: [Advances of preclinical research in xenogeneic (porcine) cell transplantation].
abstract: OBJECTIVE
  To summarize the advances of preclinical research in xenogeneic (porcine) cell transplantation in recent years.
  
  
  METHODS
  The literature about the preclinical research in xenogeneic (porcine) cell transplantation was analyzed and summarized.
  
  
  RESULTS
  With the application of new immunosuppressive agents and the generation of transgenic pigs, great progress has been achieved in xenogeneic transplantation of pig-derived nerve cells, islet cells, liver cells, and various types of stem cells. The survival time of xenogeneic cell (porcine) significantly prolonged, but there is still a long way to go before clinical application.
  
  
  CONCLUSIONS
  The source ofxenogeneic (porcine) cells is abundant and the experiments are reproducible. However, how to effectively prevent rejection and prolong the survival time in the host, and avoid the spread of virus between species are still need to be solved in the future research.
authors.forename: Xiaonan
authors.initials: X
authors.lastname: Zhou
authors.forename: Yanshuang
authors.initials: Y
authors.lastname: Wu
authors.forename: Lei
authors.initials: L
authors.lastname: Lei
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D017690:Cell Transplantation; D007515:Islets of Langerhans; D016381:Islets of Langerhans Transplantation; D013552:Swine / Q000235:genetics*; D014183:Transplantation, Heterologous / Q000379:methods* / Q000639:trends