title: Value of Fluorodeoxyglucose PET/Computed Tomography Patient Management and Outcomes in Thyroid Cancer.
abstract: "Fluorodeoxyglucose (FDG) PET/computed tomography (CT) is used most frequently in the surveillance of iodine-refractory differentiated thyroid cancer with increased thyroglobulin level after therapy. This article evaluates the impact of FDG-PET/CT on clinical management and the prognostic implications of a positive scan. In the studies reviewed, FDG-PET/CT changed the course of management in 14% to 78% of patients with suspected recurrence, and a positive scan was associated with poorer survival. Similar conclusions are supported in the literature for anaplastic and medullary thyroid cancers, although these are based on fewer studies on account of the lower prevalence of these subtypes."
authors.affiliation: Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 601 N Caroline Street, Baltimore, MD 21287, USA. Electronic address: aciaral1@jhmi.edu.
authors.forename: Anthony
authors.initials: A
authors.lastname: Ciarallo
authors.affiliation: Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 601 N Caroline Street, Baltimore, MD 21287, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Marcus
authors.affiliation: Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 601 N Caroline Street, Baltimore, MD 21287, USA.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Taghipour
authors.affiliation: Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 601 N Caroline Street, Baltimore, MD 21287, USA; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 601 North Caroline Street, Baltimore, MD, USA; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 624 North Broadway, Baltimore, MD 21205, USA.
authors.forename: Rathan M
authors.initials: RM
authors.lastname: Subramaniam
mesh_terms: D000328:Adult; D000368:Aged; D018276:Carcinoma, Medullary / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods; D009362:Neoplasm Metastasis; D049268:Positron-Emission Tomography / Q000379:methods*; D011379:Prognosis; D019275:Radiopharmaceuticals; D065646:Thyroid Carcinoma, Anaplastic / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D055815:Young Adult
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: FDG; Outcome; PET/CT; Prognosis; Thyroid cancer