title: [Ribosome: lessons of a molecular factory construction].
abstract: Ribosome is a macromolecular complex, which is responsible for protein biosynthesis. Two bacterial ribosomal subunits contain more than 4000 RNA nucleotides and 50 proteins. Ribosome assembly is a complicated multi-step process, vitally important for cell. In this review we summarised present-day conceptions about the mechanism of the bacterial ribosome assembly in the cell and in vitro model systems. Some details of the assembly of this machinery are still-unknown.
authors.forename: O V
authors.initials: OV
authors.lastname: Sergeeva
authors.forename: P V
authors.initials: PV
authors.lastname: Sergiev
authors.forename: A A
authors.initials: AA
authors.lastname: Bogdanov
authors.forename: O A
authors.initials: OA
authors.lastname: Dontsova
mesh_terms: D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism; D020558:GTP Phosphohydrolases / Q000378:metabolism; D020365:RNA Helicases / Q000378:metabolism; D012335:RNA, Ribosomal / Q000378:metabolism*; D012269:Ribosomal Proteins / Q000235:genetics / Q000378:metabolism*; D054681:Ribosome Subunits, Large, Bacterial / Q000378:metabolism; D054680:Ribosome Subunits, Small, Bacterial / Q000378:metabolism; D012270:Ribosomes / Q000235:genetics / Q000378:metabolism
chemical_list: D012335:RNA, Ribosomal; D012269:Ribosomal Proteins; D020558:GTP Phosphohydrolases; D020365:RNA Helicases