title: Neodymium:Yttrium aluminum garnet laser in the management of oral leukoplakia: A case series.
abstract: OBJECTIVE
  Oral leukoplakia is a nonscrappable whitish patch described as a potentially malignant disorder with high prevalence in India. Besides medicinal treatment, neodymium: Yttrium aluminum garnet (Nd: YAG) laser is also used for the management of oral leukoplakia. This study evaluated the role of Nd: YAG laser in the management of oral leukoplakia and also investigated postoperative complications along with long-term prognosis of the disease.
  
  
  METHODS
  The study is a prospective cohort study conducted for 24 months (June 2011 to May 2013) in Lucknow.
  
  
  METHODS
  The study comprised of 42 patients, both male and female of Indian origin and diagnosed with oral leukoplakic lesions. Patients with biopsy proven squamous cell carcinoma and medically compromised are excluded from the study. All patients has undergone ablation of lesion by pulsed Nd: YAG laser and were followed after 24 h, 72 h, 1-week and then successively for 1, 3, 6 months and then 1(st) and 2(nd) postoperative years.
  
  
  RESULTS
  Pain and slough were evaluated by Wicoxon rank test (P = 0.0001 statistically significant) which decreased from 24 h to 1-week and became nil in subsequent follow-ups. Similarly, McNemar's test (P = 0.001 statistically significant) was used for evaluation of burning sensation, paresthesia, infection and recurrences. Recurrence was noted in 2 patients but following the second application, there were no recurrences over the period of further follow-up. None of the patient suffered from an infection, paresthesia or anesthesia.
  
  
  CONCLUSIONS
  Hence, Nd: YAG laser was found to be effective in ablating leukoplakia. It is convenient, economical with minimum complications and morbidities.
authors.affiliation: Department of Head and Neck Oncology, Mazumdar Shaw Cancer Centre, Narayana Hrudalaya, Bengaluru, Karnataka, India.
authors.forename: Somdipto
authors.initials: S
authors.lastname: Das
authors.affiliation: Department of Oral and Maxillofacial Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Shadab
authors.initials: S
authors.lastname: Mohammad
authors.affiliation: Department of Oral and Maxillofacial Surgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Vibha
authors.initials: V
authors.lastname: Singh
authors.affiliation: Department of Oral and Maxillofacial Pathology, King George's Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Shalini
authors.initials: S
authors.lastname: Gupta
keywords: Ablation; neodymium: Yttrium aluminum garnet laser; oral leukoplakia
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