title: The prevalence of latent tuberculosis infection and smear positive pulmonary tuberculosis in people with household close contact with tuberculosis in north of iran.
abstract: One of the recommended strategies for preventing tuberculosis is to screen high-risk populations with respect to Mycobacterium tuberculosis (TB) infection. The aim of the present study was to investigate latent infection and active tuberculosis in people with close household contact. It was a cross-sectional descriptive, analytical study with the sample size of 668 people from homes with one infected resident. In order to diagnose tuberculosis latent infection, the PPD test was done. To determine patients with smear-positive pulmonary tuberculosis, three sputum samples were taken from every patient and were examined using direct microscopy and culture. Data was analyzed by SPSS20 software. The prevalence of latent tuberculosis infection and smear-positive pulmonary tuberculosis were 42.8% and 0.9% respectively. The prevalence of latent tuberculosis infection and smear-positive pulmonary tuberculosis in people with close household contact were less than that of other studies. However, smear-positive pulmonary tuberculosis in people with close household contact was 199.5 times more than that of the general population.
authors.affiliation: Health Sciences Research Center, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran;
authors.forename: Mahmood
authors.initials: M
authors.lastname: Moosazadeh
authors.affiliation: Research Center for Environmental Health Engineering, Kerman Medical University, Kerman, Iran;
authors.forename: Narges
authors.initials: N
authors.lastname: Khanjani
authors.affiliation: Health Deputy, Kerman University of Medical Sciences, Kerman, Iran.
authors.forename: Mohammadreza
authors.initials: M
authors.lastname: Parsaee
keywords: Household close contact; Iran; Prevalence; Tuberculosis
references.citation: Lancet Infect Dis. 2008 Jun;8(6):359-68
references.pmid: 18450516
references.citation: Value Health. 2008 Sep-Oct;11(5):842-52
references.pmid: 18489519
references.citation: Med Clin (Barc). 1997 Mar 15;108(10):361-5
references.pmid: 9139141
references.citation: Arch Iran Med. 2006 Jul;9(3):208-12
references.pmid: 16859052
references.citation: Int J Tuberc Lung Dis. 2002 Oct;6(10):851-7
references.pmid: 12365570
references.citation: Int J Tuberc Lung Dis. 2008 Mar;12(3):281-7
references.pmid: 18284833
references.citation: Arch Bronconeumol. 2007 Jun;43(6):317-23
references.pmid: 17583641
references.citation: Eur Respir J. 2013 Jan;41(1):140-56
references.pmid: 22936710
references.citation: Lancet. 1995 Feb 18;345(8947):416-9
references.pmid: 7853950
references.citation: J Infect Chemother. 2008 Feb;14(1):66-71
references.pmid: 18297454