title: Measurement of body composition as a surrogate evaluation of energy balance in obese patients.
abstract: In clinical practice obesity is primarily diagnosed through the body mass index. In order to characterize patients affected by obesity the use of traditional anthropometric measures appears misleading. Beyond the body mass index, there are overwhelming evidences towards the relevance of a more detailed description of the individual phenotype by characterizing the main body components as free-fat mass, muscle mass, and fat mass. Among the numerous techniques actually available, bioelectrical impedance analysis seems to be the most suitable in a clinical setting because it is simple, inexpensive, noninvasive, and highly reproducible. To date, there is no consensus concerning the use of one preferred equation for the resting energy expenditure in overweight and/or obese population. Energy restriction alone is an effective strategy to achieve an early and significant weight loss, however it results in a reduction of both fat and lean mass therefore promoting or aggravating an unfavourable body composition (as sarcobesity) in terms of mortality and comorbidities. Therefore the implementation of daily levels of physical activity should be simultaneously promoted. The major role of muscle mass in the energy balance has been recently established by the rising prevalence of the combination of two condition as sarcopenia and obesity. Physical exercise stimulates energy expenditure, thereby directly improving energy balance, and also promotes adaptations such as fiber type, mitochondrial biogenesis, improvement of insulin resistance, and release of myokines, which may influence different tissues, including muscle.
authors.affiliation: Carlo Maria Rotella, Ilaria Dicembrini, Section of Endocrinology, Department of Biomedical, Experimental and Clinical Sciences, University of Florence Medical School, 50121 Firenze, Italy.
authors.forename: Carlo Maria
authors.initials: CM
authors.lastname: Rotella
authors.affiliation: Carlo Maria Rotella, Ilaria Dicembrini, Section of Endocrinology, Department of Biomedical, Experimental and Clinical Sciences, University of Florence Medical School, 50121 Firenze, Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Dicembrini
keywords: Bioelectrical impedance analysis; Body composition; Energy expenditure; Obesity; Sarcobesity
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