title: Topical Review: Eosinophilic Esophagitis in Children: Implications for Health-Related Quality of Life and Potential Avenues for Future Research.
abstract: OBJECTIVE
  To characterize the health-related quality of life (HRQoL) of children with eosinophilic esophagitis (EoE) as well as generate novel hypotheses for future research in this pediatric population.
  
  
  METHODS
  A literature review was completed using PubMed and the keywords below.
  
  
  RESULTS
  Research has shown that for children with EoE and their parents, symptom experiences and recommended treatments can have a negative impact on HRQoL. However, studies have yet to adequately address mechanisms that may help explain why this is. Areas of interest include sleep quality and disturbances, the experience of pain, and the presence of internalizing symptoms, all of which have the potential to uniquely and synergistically impact HRQoL.
  
  
  CONCLUSIONS
  With greater understanding of the associations among sleep, pain, internalizing symptoms, and HRQoL in children with EoE may come enhanced therapies that substantially improve the quality of their health care.
authors.affiliation: Department of Psychology and lynchmk@uab.edu.
authors.forename: Mary K
authors.initials: MK
authors.lastname: Lynch
authors.affiliation: Department of Pediatrics, University of Alabama at Birmingham.
authors.forename: Kristin T
authors.initials: KT
authors.lastname: Avis
authors.affiliation: Department of Pediatrics, University of Alabama at Birmingham.
authors.forename: Reed A
authors.initials: RA
authors.lastname: Dimmitt
authors.affiliation: Department of Psychology and.
authors.forename: Burel R
authors.initials: BR
authors.lastname: Goodin
mesh_terms: D002648:Child; D002675:Child, Preschool; D057765:Eosinophilic Esophagitis / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D007389:Internal-External Control; D008297:Male; D010146:Pain / Q000150:complications; D010290:Parents; D011788:Quality of Life; D012106:Research / Q000639:trends*; D012893:Sleep Wake Disorders / Q000150:complications
keywords: Eosinophilic esophagitis; health-related quality of life; pain; pediatric; sleep
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