title: Next-Generation Sequencing: Targeting Targeted Therapies.
abstract: Next-generation sequencing (NGS) has given new perspective in oncology. With the ongoing development of targeted therapies, NGS is evolving molecular diagnostics by providing comprehensive interrogation of clinically actionable genomic aberrations in tumors. Having this assay as the primary testing method produces clinically beneficial results. See related article by Drilon et al., p. 3631.
authors.affiliation: Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia.
authors.forename: Justine N
authors.initials: JN
authors.lastname: McCutcheon
authors.affiliation: Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia. gg496@georgetown.edu.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Giaccone
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics*; D005260:Female; D015321:Gene Rearrangement; D015894:Genome, Human; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics*; D008297:Male