title: In reply—Early goal-directed therapy for severe sepsis.
authors.affiliation: Mayo Clinic, Rochester, MN.
authors.forename: Kannan
authors.initials: K
authors.lastname: Ramar
authors.affiliation: Mayo Clinic, Rochester, MN.
authors.forename: Brittany L
authors.initials: BL
authors.lastname: Siontis
mesh_terms: D005260:Female; D006801:Humans; D008585:Meningitis, Meningococcal / Q000175:diagnosis*; D009102:Multiple Organ Failure / Q000175:diagnosis*; D011693:Purpura / Q000175:diagnosis*; D055665:Purpura Fulminans / Q000175:diagnosis*