title: Prosthodontic rehabilitation for a patient with acromegaly.
abstract: Acromegaly is a condition which results from an excess of growth hormone produced by the pituitary gland after epiphyseal plate closure at puberty. The most common cause of acromegaly is a benign pituitary adenoma. Acromegaly is characterised by enlargement of the hands, feet, nose and ears; expansion of the skull and pronounced brow protrusion. From an oral standpoint, the most relevant symptoms are mandibular protrusion, spacing of the lower teeth and macroglossia. A 46 year-old patient was referred to University Dental School and Hospital by her General Dental Practitioner. The patient had been diagnosed with acromegaly and was receiving medical care from a consultant endocrinologist. The patient was partially dentate with only her lower anterior dentition remaining. She was wearing a complete upper denture but was unable to function effectively due to a lack of occlusal support. Treatment comprised non-surgical periodontal management, construction of upper and lower removable prostheses in a class III relationship and composite restorations on the remaining lower teeth.
authors.forename: G
authors.initials: G
authors.lastname: McKenna
authors.forename: M
authors.initials: M
authors.lastname: Hayes
authors.forename: F M
authors.initials: FM
authors.lastname: Burke
mesh_terms: D000172:Acromegaly / Q000150:complications*; D003188:Composite Resins / Q000737:chemistry; D017742:Dental Care for Chronically Ill; D003764:Dental Materials / Q000737:chemistry; D003793:Dental Restoration, Permanent / Q000379:methods; D003779:Denture Design; D003827:Denture, Complete, Upper; D003832:Denture, Partial, Removable; D005260:Female; D006801:Humans; D007575:Jaw, Edentulous / Q000534:rehabilitation; D007576:Jaw, Edentulous, Partially / Q000534:rehabilitation; D008313:Malocclusion, Angle Class III / Q000534:rehabilitation; D008334:Mandible / Q000473:pathology; D008437:Maxilla / Q000473:pathology; D008875:Middle Aged; D009065:Mouth Rehabilitation / Q000379:methods*; D010510:Periodontal Diseases / Q000628:therapy
chemical_list: D003188:Composite Resins; D003764:Dental Materials