title: Hoping Is Coping: A Guiding Theoretical Framework for Promoting Coping and Adjustment Following Pediatric Cancer Diagnosis.
abstract: OBJECTIVE
  To determine the pattern of resilience and adjustment following pediatric cancer diagnosis and to evaluate hope as a mediator of adjustment.
  
  
  METHODS
  61 participants with pediatric cancer completed measures of hope, depression, anxiety, and quality of life (QoL) within 4 weeks of cancer diagnosis and every 3 months for 1 year.
  
  
  RESULTS
  Participants showed high and increasing levels of hope and QoL, as well as low and decreasing levels of depression and anxiety. Linear mixed-effects regression analyses revealed changes in depression, anxiety, and hope to be significant predictors of changes in QoL. Changes in hope were found to partially mediate the effects of depression and anxiety on QoL.
  
  
  CONCLUSIONS
  While a variety of interventions are efficacious for treating anxiety and depression, hope theory provides a framework for choosing interventions that may more globally promote children's ability to maintain good functioning, adjustment, well-being, and QoL following cancer diagnosis.
authors.affiliation: Department of Psychiatry, Children's Health Children's Medical Center Dallas, University of Texas Southwestern Medical Center, julie.germann@childrens.com.
authors.forename: Julie N
authors.initials: JN
authors.lastname: Germann
authors.affiliation: Department of Clinical Research, Children's Health Children's Medical Center Dallas.
authors.forename: David
authors.initials: D
authors.lastname: Leonard
authors.affiliation: Pauline Allen Gill Center for Cancer and Blood Disorders, Children's Health Children's Medical Center Dallas, and.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Stuenzi
authors.affiliation: Department of Psychiatry, Children's Health Children's Medical Center Dallas.
authors.forename: Radu B
authors.initials: RB
authors.lastname: Pop
authors.affiliation: Department of Psychiatry, Children's Health Children's Medical Center Dallas, University of Texas Southwestern Medical Center.
authors.forename: Sunita M
authors.initials: SM
authors.lastname: Stewart
authors.affiliation: Pauline Allen Gill Center for Cancer and Blood Disorders, Children's Health Children's Medical Center Dallas, and Department of Pediatrics, University of Texas Southwestern Medical Center Dallas.
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Leavey
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D001007:Anxiety / Q000523:psychology*; D002648:Child; D003863:Depression / Q000523:psychology*; D005260:Female; D065026:Hope; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000523:psychology*; D011788:Quality of Life / Q000523:psychology*
keywords: anxiety; depression; hope; pediatric cancer; quality of life; resilience