title: Vitamin D, allergies and asthma: focus on pediatric patients.
abstract: In recent years, the interest of the scientific world towards vitamin D gradually increased, and several studies have been conducted to dissect its possible role in modulating the development/course of allergic diseases. Also, Vitamin D supplementation has been assessed as a beneficial approach for treating allergies in some, but not all studies. We reviewed herein the available and relevant literature concerning the possible links between Vitamin D, its supplementation and allergic diseases. A literature search was made independently by the Authors, identifying articles for a narrative review. As per literature, Vitamin D plays a key role in calcium and phosphate metabolism, and it is essential for bone health in infants, children and adolescents. However, there is presently insufficient evidence to support vitamin D supplementation for prevention or treatment of allergic diseases in infants, children and adolescents, concerning allergic rhinitis, asthma, food allergy and atopic dermatitis.
authors.affiliation: Department of Pediatrics, National Healthcare System Fornovo, Parma, Italy.
authors.forename: Auro
authors.initials: A
authors.lastname: Della Giustina
authors.affiliation: Department of Pediatrics, National Healthcare System ASL TO1, Turin, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Landi
authors.affiliation: Pediatric Unit Department of Gynecologic, Obstetric and Pediatric Sciences, University of Bologna, Bologna, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Bellini
authors.affiliation: Pediatric Unit, G. Fornaroli Hospital, Magenta, Milan, Italy.
authors.forename: Mariangela
authors.initials: M
authors.lastname: Bosoni
authors.affiliation: Department of Sciences for Health Promotion and mother and child, University of Palermo, Palermo, Italy.
authors.forename: Giuliana
authors.initials: G
authors.lastname: Ferrante
authors.affiliation: Department of Prato, Environmental Protection Agency of Tuscany (ARPAT), Prato, Italy.
authors.forename: Marzia
authors.initials: M
authors.lastname: Onorari
authors.affiliation: Aerobiological Monitoring Center, University of Tor Vergata, Rome, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Travaglini
authors.affiliation: Allergology Unit, G.B.Grassi Hospital, Rome, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Pingitore
authors.affiliation: Allergy and Respiratory Diseases, IRCCS San Martino-Ist-University of Genoa, Pad. Maragliano, L.go R Benzi 10, 16133 Genoa, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Passalacqua
authors.affiliation: Department of Pediatrics and Allergy Unit Sandro Pertini Hospital, Rome, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Tripodi
keywords: Allergic diseases; Asthma; Immunomodulation; Pediatric allergy; Rhinitis; Supplementation; Vitamin D
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