title: Maxillary dental anomalies in patients with cleft lip and palate: a cone beam computed tomography study.
abstract: OBJECTIVE
  To compare the frequency of maxillary dental anomalies in patients affected by unilateral (UCLP) and bilateral (BCLP) cleft lip with palate and to determine whether statistical differences were present or not between cleft and normal sides in UCLP group by using cone beam computed tomography (CBCT). In addition, the frequency of those dental anomalies was compared with previous studies presenting the same population without cleft Study Design: Fifty non-syndromic patients affected by UCLP (28 patients) and BCLP (22 patients) were selected for analysis of dental anomalies by means of CBCT. The frequency of maxillary dental anomalies including tooth agenesis, microdontia of lateral incisor, ectopic eruption and impaction of canine and supernumerary tooth were examined. Pearson chi-square and Fisher's exact tests were performed for statistical comparisons.
  
  
  RESULTS
  All patients affected by UCLP and BCLP were found to have at least one maxillary dental anomaly. The most frequently observed dental anomaly was tooth agenesis (92.5% and 86.4%, respectively) in UCLP and BCLP groups. Tooth agenesis and canine impaction were observed more commonly in the cleft side (75.0% and 35.7%, respectively) than in the normal side (57.1% and 14.3%, respectively) in UCLP group (p≯0.05). All dental anomalies were found to be higher in both cleft groups than in general populations not affected by cleft.
  
  
  CONCLUSIONS
  Since patients affected by UCLP and BCLP had at least one dental anomaly and higher dental anomaly frequency as compared to patients without cleft, those patients should be examined carefully prior to orthodontic treatment.
authors.affiliation: Department of Orthodontics, Faculty of Dentistry, Akdeniz University, Antalya, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Celikoglu
authors.affiliation: Ordu University, Ordu, Turkey.
authors.forename: S K
authors.initials: SK
authors.lastname: Buyuk
authors.affiliation: Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Erciyes University, Kayseri, Turkey.
authors.forename: A E
authors.initials: AE
authors.lastname: Sekerci
authors.affiliation: Department of Pedodontics, Faculty of Dentistry, Erciyes University, Kayseri, Turkey.
authors.forename: K
authors.initials: K
authors.lastname: Cantekin
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Karadeniz Technical University, Trabzon, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Candirli
mesh_terms: D000293:Adolescent; D000328:Adult; D000848:Anodontia / Q000000981:diagnostic imaging; D002648:Child; D002971:Cleft Lip / Q000000981:diagnostic imaging*; D002972:Cleft Palate / Q000000981:diagnostic imaging*; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D003481:Cuspid / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007180:Incisor / Q000002:abnormalities; D008297:Male; D008437:Maxilla / Q000000981:diagnostic imaging*; D012189:Retrospective Studies; D014071:Tooth Abnormalities / Q000000981:diagnostic imaging*; D014079:Tooth Eruption, Ectopic / Q000000981:diagnostic imaging; D014095:Tooth, Impacted / Q000000981:diagnostic imaging; D014096:Tooth, Supernumerary / Q000000981:diagnostic imaging; D055815:Young Adult
keywords: Dental anomaly; cleft lip; cleft palate; cone beam computed tomography