title: Schwannoma located in the upper gingival mucosa: case report and literature review.
abstract: The Schwannoma is a benign tumor that originates from Schwann cells of peripheral motor and sensory nerves. It presents as a solitary, slow growing, smooth-surfaced and asymptomatic firm mass. The pre-operative diagnosis is often difficult, and in majority of cases it can only be made during the surgery and the definitive diagnosis obtained by histological study when cells test positive for S-100 protein. In this report, a case of a 20-year-old female patient with a Schwannoma located in the upper gingival mucosa is discussed. The patient was referred to the department of oral and maxillofacial surgery with chief complaint of enlargement of the upper gingival mucosa at the level of upper right premolar. Clinical findings showed characteristics of connective tissue tumor including epulis; however, histologic and immunohistochemical studies revealed it to be a Schwannoma. There has been no sign of recurrence 1 year and 8 months after surgery.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Emi
authors.initials: E
authors.lastname: Nishijima Sakanashi
authors.affiliation: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Junya
authors.initials: J
authors.lastname: Sonobe
authors.affiliation: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Motofumi
authors.initials: M
authors.lastname: Chin
authors.affiliation: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Bessho
keywords: Gingival mucosa; S-100 protein; Schwannoma; Soft tissue tumors
references.citation: J Craniomaxillofac Surg. 2006 Jan;34(1):38-42
references.pmid: 16343919
references.citation: Med Oral Patol Oral Cir Bucal. 2009 Sep 01;14(9):e465-8
references.pmid: 19415055
references.citation: J Oral Maxillofac Surg. 2001 Jul;59(7):802-4
references.pmid: 11429745
references.citation: Am J Otolaryngol. 2003 Sep-Oct;24(5):351-4
references.pmid: 13130452
references.citation: Acta Otolaryngol. 2002 Jun;122(4):458-62
references.pmid: 12126009
references.citation: J Oral Maxillofac Surg. 1993 Jul;51(7):769-71
references.pmid: 8509917
references.citation: J Oral Maxillofac Surg. 2000 Oct;58(10 ):1173-5
references.pmid: 11021717
references.citation: Oral Surg Oral Med Oral Pathol. 1967 Oct;24(4):510-26
references.pmid: 5235477
references.citation: Minerva Stomatol. 1993 Apr;42(4):173-8
references.pmid: 8413099
references.citation: J Oral Maxillofac Surg. 1998 Oct;56(10 ):1191-6
references.pmid: 9766546
references.citation: Am J Otolaryngol. 2003 Sep-Oct;24(5):348-50
references.pmid: 13130451
references.citation: Yonsei Med J. 2002 Oct;43(5):678-80
references.pmid: 12402385