title: Effect of supplemental vitamin E on the peripheral blood leukocyte population in Japanese Black calves.
abstract: We investigated the effect of supplemental vitamin E on the peripheral blood leukocyte population in Japanese Black calves. Twenty-six calves kept at the same farm were studied. They were divided into two groups; thirteen calves received 300 IU/day of vitamin E orally from 1 to 3 months of age (VE group), and the other thirteen calves did not receive the vitamin E supplement (control group). The VE group showed a higher serum vitamin E concentration at 2 and 3 months of age compared with the control group (P<0.01). The numbers of CD3(+) cells and CD4(+) cells were higher in the VE group than in the control group, and the difference was statistically significant at 3 months of age (P<0.05). The numbers of CD21(+) cells were higher in the VE group than in the control group, and the difference was statistically significant at 2 months of age (P<0.05). The numbers of CD335(+) cells tended to be higher in the VE group than in the control group. The numbers of CD8(+) cells and CD14(+) cells tended to be higher in the VE group than in the control group at 3 and 4 months of age. This study demonstrated that the supplementation of suckling Japanese Black calves with vitamin E might affect the numbers of some immune cell types in the peripheral blood.
authors.affiliation: Kagoshima Prefectural Federation of Agricultural Mutual Aid Associations, Kagoshima 891-0132, Japan.
authors.forename: Konosuke
authors.initials: K
authors.lastname: Otomaru
authors.forename: Shun
authors.initials: S
authors.lastname: Saito
authors.forename: Karura
authors.initials: K
authors.lastname: Endo
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kohiruimaki
authors.forename: Hiromichi
authors.initials: H
authors.lastname: Ohtsuka
mesh_terms: D000818:Animals; D017252:CD3 Complex / Q000276:immunology; D018791:CD4 Lymphocyte Count / Q000662:veterinary; D015496:CD4-Positive T-Lymphocytes / Q000187:drug effects; D002417:Cattle / Q000276:immunology*; D002784:Cholesterol / Q000097:blood; D019587:Dietary Supplements; D007958:Leukocyte Count / Q000662:veterinary; D007962:Leukocytes / Q000187:drug effects*; D016131:Lymphocyte Subsets / Q000187:drug effects; D014810:Vitamin E / Q000097:blood / Q000494:pharmacology*
chemical_list: D017252:CD3 Complex; D014810:Vitamin E; D002784:Cholesterol
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