title: Do all components of the metabolic syndrome cluster together in U.S. Hispanics/Latinos? Results from the Hispanic Community Health study/Study of Latinos.
abstract: OBJECTIVE
  Metabolic syndrome (MetS), the clustering of several risk factors for cardiovascular disease, is highly prevalent in Hispanics/Latinos. We tested whether all components significantly loaded on the syndrome in Hispanics/Latinos and whether their contribution differed by sex and Hispanic ancestry. We also examined associations of MetS with prevalent diabetes and coronary heart disease in Hispanics/Latinos.
  
  
  METHODS
  Data were obtained from a population-based cohort of n = 15,823 participants in the HCHS/SOL study who self-identified as being of Central American, Cuban, Dominican, Mexican American, Puerto Rican, or South American ancestry and were aged 18 to 74 years at screening.
  
  
  RESULTS
  A latent variable model of waist circumference, systolic and diastolic blood pressure, triglycerides, high-density lipoprotein cholesterol (HDL-C), and fasting glucose fit the data in men and women, but the contribution of HDL-C was weak. No difference in the latent model of MetS was detected across Hispanic/Latino ancestry groups. MetS was significantly associated with diabetes and coronary heart disease.
  
  
  CONCLUSIONS
  Our results indicate that similar criteria for MetS may be applied across Hispanic/Latino ancestry groups but call into question the role of HDL-C in classifying the MetS in Hispanics/Latinos.
authors.affiliation: Department of Psychology, University of Miami, Coral Gables, FL. Electronic address: mllabre@miami.edu.
authors.forename: Maria M
authors.initials: MM
authors.lastname: Llabre
authors.affiliation: Department of Psychology, University of Miami, Coral Gables, FL.
authors.forename: William
authors.initials: W
authors.lastname: Arguelles
authors.affiliation: Department of Psychology, University of Miami, Coral Gables, FL.
authors.forename: Neil
authors.initials: N
authors.lastname: Schneiderman
authors.affiliation: Department of Psychology, San Diego State University, San Diego, CA.
authors.forename: Linda C
authors.initials: LC
authors.lastname: Gallo
authors.affiliation: Institute for Minority Health Research, College of Medicine, University of Illinois, Chicago, IL.
authors.forename: Martha L
authors.initials: ML
authors.lastname: Daviglus
authors.affiliation: Department of Family and Social Medicine, Albert Einstein College of Medicine, Bronx, NY.
authors.forename: Earle C
authors.initials: EC
authors.lastname: Chambers
authors.affiliation: Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
authors.forename: Daniela
authors.initials: D
authors.lastname: Sotres-Alvarez
authors.affiliation: Department of Psychology, University of Miami, Coral Gables, FL.
authors.forename: Diana A
authors.initials: DA
authors.lastname: Chirinos
authors.affiliation: Department of Health Promotion/Behavioral Science, Graduate School of Public Health, San Diego State University, San Diego, CA.
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Talavera
authors.affiliation: Institute for Behavioral and Community Health, Graduate School of Public Health, San Diego State University, San Diego, CA.
authors.forename: Sheila F
authors.initials: SF
authors.lastname: Castaneda
authors.affiliation: Department of Psychology, San Diego State University, San Diego, CA.
authors.forename: Scott C
authors.initials: SC
authors.lastname: Roesch
authors.affiliation: Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
authors.forename: Gerardo
authors.initials: G
authors.lastname: Heiss
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001786:Blood Glucose; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000208:ethnology; D016000:Cluster Analysis; D003327:Coronary Disease / Q000208:ethnology*; D003920:Diabetes Mellitus / Q000208:ethnology*; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000208:ethnology*; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D012959:Socioeconomic Factors; D014481:United States / Q000453:epidemiology; D055105:Waist Circumference; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D008055:Lipids
keywords: Hispanics; Lipids; Metabolic syndrome
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