title: Ruthenium-catalyzed ortho-C-H mono- and di-imidation of arenes with N-tosyloxyphthalimide.
abstract: The Ru(II)-catalyzed imidation of the o-C-H bond in arenes with N-tosyloxyphthalimide is realized with the assistance of a methyl phenylsulfoximine (MPS) directing group. This method is applicable to access the hitherto difficult o-C-H di-imidation products. The sequential C-N and C-C bond formation of o-C-H arenes creates peripherally decorated benzoic acid derivatives. The readily removable MPS-DG and easily modifiable phthaloyl moiety make this strategy synthetically viable for constructing highly functionalized C-N bearing arenes and heteroarenes.
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad-500046, India.
authors.forename: M Ramu
authors.initials: MR
authors.lastname: Yadav
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad-500046, India.
authors.forename: Majji
authors.initials: M
authors.lastname: Shankar
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad-500046, India.
authors.forename: E
authors.initials: E
authors.lastname: Ramesh
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad-500046, India.
authors.forename: Koushik
authors.initials: K
authors.lastname: Ghosh
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad-500046, India.
authors.forename: Akhila K
authors.initials: AK
authors.lastname: Sahoo