title: Further evidence for a pain pathway involving the cingulate gyrus: a case of chronic cluster headache cured by glioblastoma.
abstract: The authors report a case of a 49-year-old man with long-standing, chronic cluster headache (CH) refractory to medical therapy and occipital nerve stimulation that resolved a few weeks prior to the diagnosis of glioblastoma involving primarily the right cingulate gyrus. An attempt to explore the underlying role of the cingulate cortex in pain modulation by appraising the current literature is presented. This report suggests that the cingulate gyri could be a potential target for neuromodulation in patients with medically refractory chronic CH.
authors.affiliation: Department of Neurosurgery, Henry Ford Hospital, Detroit, Mich., USA.
authors.forename: Adam M
authors.initials: AM
authors.lastname: Robin
authors.forename: Aqueel H
authors.initials: AH
authors.lastname: Pabaney
authors.forename: Panayiotis D
authors.initials: PD
authors.lastname: Mitsias
authors.forename: Jason M
authors.initials: JM
authors.lastname: Schwalb
mesh_terms: D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D003027:Cluster Headache / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D004599:Electric Stimulation Therapy / Q000379:methods; D004567:Electrodes, Implanted; D005909:Glioblastoma / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006179:Gyrus Cinguli / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000150:complications / Q000175:diagnosis*