title: Disseminated histoplasmosis caused by Histoplasma capsulatum var. duboisii in a non-HIV patient in Burkina Faso: Case report.
abstract: Histoplasmosis is a fungal infection due to Histoplasma capsulatum. The African form of this mycosis, caused by Histoplasma capsulatum var. duboisii, remains rare. We report a case of disseminated African histoplasmosis with skin, lymph nodes, bones and viscera localizations. The 22-year-old patient was HIV-seronegative and was considered immunocompetent. The presence of Histoplasma capsulatum var duboisii in ulcerations and a nodule pus aspiration was confirmed by direct microscopic examination and by culture. The medical treatment was based on fluconazole. Even though a regression of the symptoms was observed, the patient died. In disseminated African histoplasmosis, an early laboratory diagnosis must be carried out for accurate treatment.
authors.affiliation: Service de parasitologie-mycologie, centre hospitalier universitaire Yalgado Ouédraogo, 03 BP 7022, Ouaga 03, Burkina Faso; Unité de formation et de recherche en sciences de la santé, université de Ouagadougou, 03 BP 7021, Ouaga 03, Burkina Faso. Electronic address: zidaadama@live.fr.
authors.forename: A
authors.initials: A
authors.lastname: Zida
authors.affiliation: Service de dermatologie-vénérologie, centre hospitalier universitaire Yalgado Ouédraogo, 03 BP 7022, Ouaga 03, Burkina Faso; Unité de formation et de recherche en sciences de la santé, université de Ouagadougou, 03 BP 7021, Ouaga 03, Burkina Faso.
authors.forename: P
authors.initials: P
authors.lastname: Niamba
authors.affiliation: Service de dermatologie-vénérologie, centre hospitalier universitaire Yalgado Ouédraogo, 03 BP 7022, Ouaga 03, Burkina Faso; Unité de formation et de recherche en sciences de la santé, université de Ouagadougou, 03 BP 7021, Ouaga 03, Burkina Faso.
authors.forename: F
authors.initials: F
authors.lastname: Barro-Traoré
authors.affiliation: Service de dermatologie-vénérologie, centre hospitalier universitaire Yalgado Ouédraogo, 03 BP 7022, Ouaga 03, Burkina Faso; Unité de formation et de recherche en sciences de la santé, université de Ouagadougou, 03 BP 7021, Ouaga 03, Burkina Faso.
authors.forename: N
authors.initials: N
authors.lastname: Korsaga-Somé
authors.affiliation: Service de dermatologie-vénérologie, centre hospitalier universitaire Yalgado Ouédraogo, 03 BP 7022, Ouaga 03, Burkina Faso; Unité de formation et de recherche en sciences de la santé, université de Ouagadougou, 03 BP 7021, Ouaga 03, Burkina Faso.
authors.forename: P
authors.initials: P
authors.lastname: Tapsoba
authors.affiliation: Service de parasitologie-mycologie, centre hospitalier universitaire Yalgado Ouédraogo, 03 BP 7022, Ouaga 03, Burkina Faso; École de santé sciences nouvelles (ESSN), 02 BP 5572, Ouaga 02, Burkina Faso.
authors.forename: J
authors.initials: J
authors.lastname: Briegel
authors.affiliation: Unité de formation et de recherche en sciences de la santé, université de Ouagadougou, 03 BP 7021, Ouaga 03, Burkina Faso.
authors.forename: R T
authors.initials: RT
authors.lastname: Guiguemdé
mesh_terms: D002050:Burkina Faso; D005260:Female; D006658:Histoplasma / Q000302:isolation & purification*; D006660:Histoplasmosis / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D055815:Young Adult
keywords: Burkina Faso; Diagnostic mycologique; Disseminated histoplasmosis; Fluconazole; HIV-seronegative patient; Histoplasma capsulatum var. duboisii; Histoplasmose disséminée; Mycological diagnosis; Patient immunocompétent