title: A liver lesion in primary sclerosing cholangitis.
abstract: Primary sclerosing cholangitis is associated with an increased risk of cholangiocarcinoma; appropriate surveillance should be undertaken for this. Our case illustrates an unexpected liver lesion in such a patient, which would not have been detected with imaging alone. In suspected cancer, if a patient is not a candidate for liver resection, liver biopsy should be considered in case there is a treatment option for an alternative cause of the liver lesion. This is a careful decision to be made due to the risk of tumour seeding compromising cure and needs to be discussed via the hepatobiliary multidisciplinary team.
authors.affiliation: Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, UK.
authors.forename: Sujata
authors.initials: S
authors.lastname: Biswas
authors.affiliation: Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, UK.
authors.forename: Neil
authors.initials: N
authors.lastname: Rajoriya
authors.affiliation: Department of Cellular Pathology, John Radcliffe Hospital, Oxford, UK.
authors.forename: Lai Mun
authors.initials: LM
authors.lastname: Wang
authors.affiliation: Translational Gastroenterology Unit, John Radcliffe Hospital, Oxford, UK.
authors.forename: Jane
authors.initials: J
authors.lastname: Collier
mesh_terms: D018281:Cholangiocarcinoma / Q000175:diagnosis* / Q000209:etiology; D015209:Cholangitis, Sclerosing / Q000150:complications*; D003937:Diagnosis, Differential; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D008545:Melanoma / Q000175:diagnosis; D008875:Middle Aged; D016896:Treatment Outcome
references.citation: World J Gastroenterol. 2008 Aug 21;14 (31):4968-71
references.pmid: 18756609
references.citation: Gut. 2012 Dec;61(12 ):1657-69
references.pmid: 22895392