title: Residual vasomotor activity assessed by heart rate variability in a brain-dead case.
abstract: A patient assessed by heart rate variability (HRV) methodology, beginning just after the completion of brain death (BD) diagnosis, showed remaining very low frequency (VLF) waves for approximately 10 min. A time-varying spectral analysis showed that during the first 550 s, a significant power spectral density remained in the high-frequency (HF), low-frequency (LF) and VLF bands. From 550 to 675 s, the HF oscillations totally vanished, and a marked progressive decay of the LF and VLF power density occurred. After 700 s the VLF undulations stopped and remaining small amplitude oscillations at 0.2 Hz coincided with the ventilator frequency. The VLF oscillations recorded in our case might be related to residual sympathetic vasomotor activity that progressively disappeared due to the extension of necrosis affecting the nervous centres of the lower part of the medulla and the first 2-3 cervical spine segments.
authors.affiliation: Department of Clinical Neurophysiology, Institute of Neurology and Neurosugery, Havana, Cuba.
authors.forename: Calixto
authors.initials: C
authors.lastname: Machado
authors.affiliation: Institute of Neurology, Havana, Cuba.
authors.forename: Mario
authors.initials: M
authors.lastname: Estevez
authors.affiliation: Hermanos Amejeiras Hospital, Havana, Cuba.
authors.forename: Jesus
authors.initials: J
authors.lastname: Perez-Nellar
authors.affiliation: Anesthesiology and Critical Care Medicine, Neurosciences Critical Care Division, Johns Hopkins Hospital, Baltimore, Maryland, USA.
authors.forename: Adam
authors.initials: A
authors.lastname: Schiavi
mesh_terms: D001926:Brain Death; D003329:Coronary Vasospasm / Q000503:physiopathology*; D003919:Diabetes Insipidus / Q000503:physiopathology*; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate; D006801:Humans; D008875:Middle Aged; D012815:Signal Processing, Computer-Assisted; D014666:Vasomotor System / Q000503:physiopathology*
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