title: Hair Regeneration Treatment Using Adipose-Derived Stem Cell Conditioned Medium: Follow-up With Trichograms.
abstract: OBJECTIVE
  Adipose-derived stem cells secrete various growth factors that promote hair growth. This study examined the effects of adipose-derived stem cell-conditioned medium on alopecia.
  
  
  METHODS
  Adipose-derived stem cell-conditioned medium was intradermally injected in 22 patients (11 men and 11 women) with alopecia. Patients received treatment every 3 to 5 weeks for a total of 6 sessions. Hair numbers were counted using trichograms before and after treatment. A half-side comparison study was also performed in 10 patients (8 men and 2 women).
  
  
  RESULTS
  Hair numbers were significantly increased after treatment in both male (including those without finasteride administration) and female patients. In the half-side comparison study, the increase in hair numbers was significantly higher on the treatment side than on the placebo side.
  
  
  CONCLUSIONS
  Treatment using adipose-derived stem cell-conditioned medium appears highly effective for alopecia and may represent a new therapy for hair regeneration.
authors.affiliation: Cherry-Blossom Plastic and Regenerative Surgery, Tokyo, Japan; and Department of Plastic and Reconstructive Surgery, Kyorin University, Tokyo, Japan.
authors.forename: Hirotaro
authors.initials: H
authors.lastname: Fukuoka
authors.affiliation: Cherry-Blossom Plastic and Regenerative Surgery, Tokyo, Japan; and Department of Plastic and Reconstructive Surgery, Kyorin University, Tokyo, Japan.
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Suga
keywords: adipose-derived stem cells; alopecia; conditioned medium; half-side comparison study; trichograms
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