title: Development of laser desorption imaging mass spectrometry methods to investigate the molecular composition of latent fingermarks.
abstract: For a century, fingermark analysis has been one of the most important and common methods in forensic investigations. Modern chemical analysis technologies have added the potential to determine the molecular composition of fingermarks and possibly identify chemicals a suspect may have come into contact with. Improvements in analytical detection of the molecular composition of fingermarks is therefore of great importance. In this regard, matrix-assisted laser desorption ionization (MALDI) and laser desorption ionization (LDI) imaging mass spectrometry (IMS) have proven to be useful technologies for fingermark analysis. In these analyses, the choice of ionizing agent and its mode of deposition are critical steps for the identification of molecular markers. Here we propose two novel and complementary IMS approaches for endogenous and exogenous substance detection in fingermarks: sublimation of 2-mercaptobenzothiazol (2-MBT) matrix and silver sputtering.
authors.affiliation: Department of Chemistry, Université de Montréal, C.P. 6128, Succursale Centre-ville, Montréal, Québec, H3C 3J7, Canada.
authors.forename: Nidia
authors.initials: N
authors.lastname: Lauzon
authors.forename: Martin
authors.initials: M
authors.lastname: Dufresne
authors.forename: Vinita
authors.initials: V
authors.lastname: Chauhan
authors.forename: Pierre
authors.initials: P
authors.lastname: Chaurand
mesh_terms: D052160:Benzothiazoles / Q000737:chemistry; D003878:Dermatoglyphics; D006801:Humans; D012834:Silver / Q000737:chemistry; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
chemical_list: D052160:Benzothiazoles; D012834:Silver; C005563:captax
references.citation: Mol Cell Proteomics. 2011 Feb;10(2):O110.004259
references.pmid: 20736411
references.citation: J Forensic Sci. 2006 Nov;51(6):1329-33
references.pmid: 17199618
references.citation: Chem Rev. 2013 Apr 10;113(4):2309-42
references.pmid: 23394164
references.citation: Chem Rev. 2010 May 12;110(5):3237-77
references.pmid: 20423155
references.citation: Anal Chem. 2011 Jul 15;83(14):5728-34
references.pmid: 21639088
references.citation: J Forensic Sci. 2011 Jan;56(1):102-8
references.pmid: 20707835
references.citation: Analyst. 2013 Aug 7;138(15):4215-28
references.pmid: 23658933
references.citation: J Am Soc Mass Spectrom. 2007 Sep;18(9):1646-52
references.pmid: 17659880
references.citation: Anal Chem. 2011 Jul 15;83(14):5585-91
references.pmid: 21667965
references.citation: Forensic Sci Int. 2014 Feb;235:68-77
references.pmid: 24447453
references.citation: Forensic Sci Int. 2012 Sep 10;221(1-3):84-91
references.pmid: 22551694
references.citation: Forensic Sci Int. 2001 Sep 1;120(3):172-6
references.pmid: 11473799
references.citation: Forensic Sci Int. 2010 Jul 15;200(1-3):28-34
references.pmid: 20395083
references.citation: Forensic Sci Int. 2010 Jun 15;199(1-3):93-102
references.pmid: 20413233
references.citation: Sci Justice. 2014 Mar;54(2):110-7
references.pmid: 24630320
references.citation: Forensic Sci Int. 2005 May 28;150(1):33-51
references.pmid: 15837007
references.citation: Analyst. 2013 May 7;138(9):2546-57
references.pmid: 23486747
references.citation: Analyst. 2009 Sep;134(9):1902-4
references.pmid: 19684917
references.citation: J Mass Spectrom. 2013 Jun;48(6):677-84
references.pmid: 23722958
references.citation: Forensic Sci Int. 2011 Apr 15;207(1-3):223-38
references.pmid: 21074340
references.citation: Analyst. 2014 Feb 7;139(3):633-42
references.pmid: 24319772
references.citation: Forensic Sci Int. 2014 May;238:68-82
references.pmid: 24675043
references.citation: Forensic Sci Int. 2013 Oct 10;232(1-3):111-24
references.pmid: 24053872
references.citation: Anal Chem. 2008 Dec 1;80(23):9105-14
references.pmid: 18959430
references.citation: Forensic Sci Int. 2005 Nov 25;154(2-3):224-39
references.pmid: 16182971
references.citation: Analyst. 2009 Apr;134(4):701-7
references.pmid: 19305918
references.citation: J Proteomics. 2012 Aug 30;75(16):4883-92
references.pmid: 22525544
references.citation: Anal Chem. 2013 Mar 19;85(6):3318-24
references.pmid: 23425078
references.citation: Science. 2008 Aug 8;321(5890):805
references.pmid: 18687956
references.citation: Forensic Sci Int. 2012 Nov 30;223(1-3):10-24
references.pmid: 22727572
references.citation: Anal Chem. 2010 Mar 1;82(5):1589-93
references.pmid: 20128591
references.citation: Rapid Commun Mass Spectrom. 2011 Feb 15;25(3):415-22
references.pmid: 21213360
references.citation: Rapid Commun Mass Spectrom. 2009 Oct;23(19):3031-9
references.pmid: 19711300
references.citation: Anal Chem. 2012 Feb 21;84(4):2048-54
references.pmid: 22243482
references.citation: Forensic Sci Int. 2013 Mar 10;226(1-3):10-21
references.pmid: 23498998
references.citation: J Am Soc Mass Spectrom. 2008 May;19(5):666-70
references.pmid: 18328728
references.citation: Forensic Sci Int. 2008 Aug 6;179(2-3):87-97
references.pmid: 18565707
references.citation: Anal Chem. 2013 Dec 17;85(24):12070-6
references.pmid: 24251730