title: Burning mouth syndrome due to herpes simplex virus type 1.
abstract: Burning mouth syndrome is characterised by chronic orofacial burning pain. No dental or medical cause has been found. We present a case of burning mouth syndrome of 6 months duration in a healthy 65-year-old woman, which was associated with high copy numbers of herpes simplex virus type 1 (HSV-1) DNA in the saliva. Her pain resolved completely after antiviral treatment with a corresponding absence of salivary HSV-1 DNA 4 weeks and 6 months later.
authors.affiliation: Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, USA.
authors.forename: Maria A
authors.initials: MA
authors.lastname: Nagel
authors.affiliation: Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, USA.
authors.forename: Alexander
authors.initials: A
authors.lastname: Choe
authors.affiliation: Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, USA.
authors.forename: Igor
authors.initials: I
authors.lastname: Traktinskiy
authors.affiliation: Department of Neurology, University of Colorado School of Medicine, Aurora, Colorado, USA Departments of Microbiology and Immunology, University of Colorado School of Medicine, Aurora, Colorado, USA.
authors.forename: Don
authors.initials: D
authors.lastname: Gilden
mesh_terms: D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use*; D002054:Burning Mouth Syndrome / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology*; D005260:Female; D018259:Herpesvirus 1, Human / Q000187:drug effects* / Q000254:growth & development*; D006801:Humans; D012463:Saliva / Q000187:drug effects / Q000821:virology*; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents
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