title: Efficacy evaluation of a cosmetic slimming treatment for the waist and hips: a double-blind study.
abstract: The aim of this study was to evaluate by clinical and noninvasive instrumental evaluations the efficacy and tolerance of a cosmetic topical slimming treatment specific for light/moderate adipose pannicula at the level of the waist and hips. The protocol was performed as a double-blind active vs placebo trial in 110 volunteers for a period of 4 weeks, with an additional visit 4 weeks after the last product application. The following clinical/instrumental evaluation was performed during the visit: clinical assessment of hip-abdomen adipose pannicula, circumference measurements, ultrasonographic evaluation of adipose pannicula thickness, and plicometry. At the end of treatment, the slimming activity of the study product resulted in clinically different results than placebo, determined by a significant decrease in abdomen/hips circumferences and considerable reduction of abdomen/hips adipose pannicula thickness. The tolerability of the product was good and the enrolled volunteers expressed their full satisfaction with the studied product.
mesh_terms: D050153:Abdominal Fat / Q000187:drug effects* / Q000378:metabolism; D000273:Adipose Tissue / Q000187:drug effects* / Q000378:metabolism; D000279:Administration, Cutaneous; D000328:Adult; D003358:Cosmetics / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D004311:Double-Blind Method; D005260:Female; D006615:Hip; D006801:Humans; D017060:Patient Satisfaction; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D003358:Cosmetics