title: Assessment of implant cumulative survival rates in sites with different bone density and related prognostic factors: an 8-year retrospective study of 2,684 implants.
abstract: OBJECTIVE
  This retrospective study was set to explore the influence of local bone density (BD) on implant cumulative survival rates (ICSRs) and to assess prognostic factors associated with implant failure at sites with different BD.
  
  
  METHODS
  Between January 2005 and December 2011, 2,684 implants were placed in 1,377 patients and included in the study. Implants at sites with different BD were divided into four groups (G1 to G4) according to the Lekholm and Zarb classification, corresponding to bone types 1 to 4. ICSRs and the reasons for failure in each group were evaluated. Factors related to the local distribution of BD were also analyzed. A number of predictive variables were examined by univariate and multivariate analyses to evaluate prognostic factors and their influence on implant failure rates.
  
  
  RESULTS
  In total, 45 implants were lost, resulting in ICSRs for G1 to G4 of 100%, 98.18%, 96.83%, and 92.25%, respectively. The main reasons for failure in each group were failed osseointegration and occlusal overloading. Low BD was associated with advanced age (> 50 years) and the posterior maxilla. Based on multivariate analysis, diabetes mellitus and nonthreaded implants were significant factors in the high-BD group (G2), while advanced age, smoking, nonthreaded implants, and immediate loading were risk factors for the low-BD group (G3 and G4).
  
  
  CONCLUSIONS
  BD is one of the most important factors influencing the long-term ICSR, which decreases with decreasing BD values. Accurate risk evaluation for sites with different BD before implantation will be beneficial to implant survival.
authors.forename: Jing
authors.initials: J
authors.lastname: He
authors.forename: Baohong
authors.initials: B
authors.lastname: Zhao
authors.forename: Chunfu
authors.initials: C
authors.lastname: Deng
authors.forename: Dehao
authors.initials: D
authors.lastname: Shang
authors.forename: Chong
authors.initials: C
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016301:Alveolar Bone Loss / Q000209:etiology; D015519:Bone Density; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D017267:Dental Prosthesis Design / Q000009:adverse effects*; D019094:Dental Prosthesis, Implant-Supported / Q000009:adverse effects*; D019232:Dental Restoration Failure; D005260:Female; D006801:Humans; D008297:Male; D008437:Maxilla / Q000601:surgery; D008875:Middle Aged; D016348:Osseointegration; D012189:Retrospective Studies; D015996:Survival Rate; D055815:Young Adult
chemical_list: D015921:Dental Implants