title: Extra-intestinal malignancies in inflammatory bowel diseases: An update with emphasis on MDCT and MR imaging features.
abstract: Inflammatory bowel diseases (IBD) are associated with an increased risk of gastrointestinal cancers and more specifically in sites affected by chronic inflammation. However, patients with IBD have also an increased risk for developing a variety of extra-intestinal cancers. In this regard, hepatobiliary cancers, such as cholangiocarcinoma, are more frequently observed in IBD patients because of a high prevalence of primary sclerosing cholangitis, which is considered as a favoring condition. Extra-intestinal lymphomas, mostly non-Hodgkin lymphomas, and skin cancers are also observed with an increased incidence in IBD patients by comparison with that in patients without IBD. This review provides an update on demographics, risk factors and clinical features of extra-intestinal malignancies, including cholangiocarcinoma, hepatocellular carcinoma and lymphoma, that occur in patients with IBD along with a special emphasis on the multidetector row computed tomography and magnetic resonance imaging features of these uncommon conditions.
authors.affiliation: Department of Abdominal Imaging, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France; Université Paris-Diderot, Sorbonne Paris Cité, 10, avenue de Verdun, 75010 Paris, France. Electronic address: anthony.dohan@lrb.aphp.fr.
authors.forename: A
authors.initials: A
authors.lastname: Dohan
authors.affiliation: Department of Radiology, centre Pierre-et-Marie-Curie, place du 1(er)-Mai, 16016 Alger, Algeria. Electronic address: faraounsid@yahoo.fr.
authors.forename: S A
authors.initials: SA
authors.lastname: Faraoun
authors.affiliation: Department of Abdominal Imaging, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address: matthias_barral@yahoo.fr.
authors.forename: M
authors.initials: M
authors.lastname: Barral
authors.affiliation: Department of Abdominal Imaging, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address: youcef.guerrache@lrb.aphp.fr.
authors.forename: Y
authors.initials: Y
authors.lastname: Guerrache
authors.affiliation: Department of Abdominal Imaging, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address: mourad.boudiaf@lrb.aphp.fr.
authors.forename: M
authors.initials: M
authors.lastname: Boudiaf
authors.affiliation: Université Paris-Diderot, Sorbonne Paris Cité, 10, avenue de Verdun, 75010 Paris, France; Department of Digestive Diseases, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address: xavier.dray@lrb.aphp.fr.
authors.forename: X
authors.initials: X
authors.lastname: Dray
authors.affiliation: Department of Radiology, hôpital Robert-Debré, 11, boulevard Pasteur, 51092 Reims cedex, France. Electronic address: choeffel-fornes@chu-reims.fr.
authors.forename: C
authors.initials: C
authors.lastname: Hoeffel
authors.affiliation: Université Paris-Diderot, Sorbonne Paris Cité, 10, avenue de Verdun, 75010 Paris, France; Department of Digestive Diseases, hôpital Saint-Louis, Assistance publique-Hôpitaux de Paris, 1, avenue Claude-Vellefaux, 75010 Paris, France. Electronic address: matthieu.allez@sls.aphp.fr.
authors.forename: M
authors.initials: M
authors.lastname: Allez
authors.affiliation: Université Paris-Diderot, Sorbonne Paris Cité, 10, avenue de Verdun, 75010 Paris, France; Department of Hepatobiliary Surgery, hôpital Beaujon, Assistance publique-Hôpitaux de Paris, 100, boulevard du Général-Leclerc, 92118 Clichy, France. Electronic address: olivier.farges@bjn.aphp.fr.
authors.forename: O
authors.initials: O
authors.lastname: Farges
authors.affiliation: Department of Gastroenterology, hôpital Saint-Antoine, Assistance publique-Hôpitaux de Paris, 184, rue du Faubourg-Saint-Antoine, 75012 Paris, France. Electronic address: laurent.beaugerie@sat.aphp.fr.
authors.forename: L
authors.initials: L
authors.lastname: Beaugerie
authors.affiliation: Department of Oncology, hôpital Avicenne, Assistance publique-Hôpitaux de Paris, 125, rue de Stalingrad, 93000 Bobigny, France. Electronic address: thomas.aparicio@avc.aphp.fr.
authors.forename: T
authors.initials: T
authors.lastname: Aparicio
authors.affiliation: Université Paris-Diderot, Sorbonne Paris Cité, 10, avenue de Verdun, 75010 Paris, France; Department of Digestive Diseases, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address: philippe.marteau@lrb.aphp.fr.
authors.forename: P
authors.initials: P
authors.lastname: Marteau
authors.affiliation: Department of Radiology, Johns Hopkins Hospital, 601N Caroline Street, JHOC 3251, Baltimore, MD 21287, USA. Electronic address: efishman@jhmi.edu.
authors.forename: E K
authors.initials: EK
authors.lastname: Fishman
authors.affiliation: Department of Radiology, hôpital Pitié-salpêtrière, Assistance publique-Hôpitaux de Paris, 47-83, boulevard de l'Hôpital, 75013 Paris, France. Electronic address: olivier.lucidarme@psl.aphp.fr.
authors.forename: O
authors.initials: O
authors.lastname: Lucidarme
authors.affiliation: Université Paris-Diderot, Sorbonne Paris Cité, 10, avenue de Verdun, 75010 Paris, France; Department of Digestive Surgery, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address: clarisse.eveno@lrb.aphp.fr.
authors.forename: C
authors.initials: C
authors.lastname: Eveno
authors.affiliation: Université Paris-Diderot, Sorbonne Paris Cité, 10, avenue de Verdun, 75010 Paris, France; Department of Digestive Surgery, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France. Electronic address: marc.pocard@inserm.fr.
authors.forename: M
authors.initials: M
authors.lastname: Pocard
authors.affiliation: Department of Abdominal Imaging, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France; Université Paris-Diderot, Sorbonne Paris Cité, 10, avenue de Verdun, 75010 Paris, France. Electronic address: raphael.dautry@lrb.aphp.fr.
authors.forename: R
authors.initials: R
authors.lastname: Dautry
authors.affiliation: Department of Abdominal Imaging, hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, France; Université Paris-Diderot, Sorbonne Paris Cité, 10, avenue de Verdun, 75010 Paris, France. Electronic address: philippe.soyer@lrb.aphp.fr.
authors.forename: P
authors.initials: P
authors.lastname: Soyer
mesh_terms: D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D061330:Multidetector Computed Tomography / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis* / Q000209:etiology; D012307:Risk Factors
keywords: Cholangiocarcinoma; Diagnostic imaging; Extra-intestinal cancer; Inflammatory bowel disease; Lymphoma