title: Dimensional psychopharmacology in somatising patients.
abstract: Despite the recent DSM-5 review of somatoform disorders, which are now called somatic symptom and related disorders, the categorical definitions of these syndromes have inherent limitations because their causal mechanism or presumed aetiologies are still unknown. These limitations may affect everyday clinical practice and decision-making abilities. As a result, physicians have limited information at their disposal to treat these patients. Furthermore, the clinical presentations of somatic disorders may vary a lot. The purpose of this chapter is to illustrate a psychopathological dimensional approach to the somatising patient. This approach is constantly unconsciously applied in clinical practice using continuous variables, such as rating scales. Moreover, treatment strategies might be improved by adding a dimensional approach, simply recognising the prominent components of the presenting psychopathology of a given patient and addressing them with drugs according to their different mechanisms, targeting circuits and neurotransmitters. Some authors have proposed a shift from the nosological to functional application of psychotropic drugs, in which functional psychopharmacology will be dysfunction oriented and therefore inevitably geared towards utilising drug combinations. Here, we present a summary of the advantages of functional/dimensional psychopharmacology for the treatment of somatic symptoms and related disorders.
authors.affiliation: Department of Neurology and Psychiatry, SAPIENZA University of Rome, Rome, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Biondi
authors.forename: Massimo
authors.initials: M
authors.lastname: Pasquini
mesh_terms: D006801:Humans; D011600:Psychopharmacology / Q000379:methods*; D013001:Somatoform Disorders / Q000175:diagnosis / Q000188:drug therapy*