title: PET with Fluorodeoxyglucose F 18/Computed Tomography in the Clinical Management and Patient Outcomes of Esophageal Cancer.
abstract: PET with fluorodeoxyglucose F 18/computed tomography ((18)F-FDG PET/CT) has evolved into an indispensable imaging technique in the management of patients with esophageal cancer. Staging with (18)F-FDG PET/CT is strongly associated with overall survival and certain (18)F-FDG PET/CT parameters predict patient survival. Current evidence supporting the validity of the use of (18)F-FDG PET/CT in the tumor delineation process for radiation treatment planning in patients with esophageal cancer is still limited. It is useful in determining treatment response after neoadjuvant therapy and thereby has an impact on management. (18)F-FDG PET/CT plays a role in the diagnosis of recurrent disease in patients with a background of clinical suspicion.
authors.affiliation: Department of Radiology, Maastricht University Medical Center, PO Box 5800, Maastricht 6202 AZ, The Netherlands.
authors.forename: Robert M
authors.initials: RM
authors.lastname: Kwee
authors.affiliation: Russell H Morgan Department of Radiology and Radiologic Sciences, Johns Hopkins University, JHOC 3230, 601 N Caroline Street, Baltimore, MD 21287, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Marcus
authors.affiliation: Russell H Morgan Department of Radiology and Radiologic Sciences, Johns Hopkins University, JHOC 3230, 601 N Caroline Street, Baltimore, MD 21287, USA.
authors.forename: Sara
authors.initials: S
authors.lastname: Sheikhbahaei
authors.affiliation: Russell H Morgan Department of Radiology and Radiologic Sciences, Johns Hopkins University, JHOC 3230, 601 N Caroline Street, Baltimore, MD 21287, USA; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, 601 North Caroline Street, Baltimore, MD, USA; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, 624 North Broadway, Baltimore, MD 21205, USA. Electronic address: rsubram4@jhmi.edu.
authors.forename: Rathan M
authors.initials: RM
authors.lastname: Subramaniam
mesh_terms: D000368:Aged; D059186:Chemoradiotherapy, Adjuvant / Q000379:methods; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000628:therapy; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods; D020360:Neoadjuvant Therapy / Q000379:methods; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000628:therapy; D009367:Neoplasm Staging; D063868:Patient Outcome Assessment; D049268:Positron-Emission Tomography / Q000379:methods*; D015641:Radiography, Interventional / Q000379:methods; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: (18)F-Fluorodeoxyglucose; Computed tomography; Esophageal cancer; Management; Positron emission tomography