title: CYP2C19*2 genotype influence in acute coronary syndrome patients undergoing serial clopidogrel dose tailoring based on platelet function testing: Analysis from randomized controlled trial NCT02096419.
authors.affiliation: University of Zagreb School of Medicine, Department for Cardiovascular Diseases, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia. Electronic address: jure.samardzic@gmail.com.
authors.forename: Jure
authors.initials: J
authors.lastname: Samardzic
authors.affiliation: University of Zagreb School of Medicine, Department for Laboratory Diagnostics, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia.
authors.forename: Nada
authors.initials: N
authors.lastname: Bozina
authors.affiliation: University of Zagreb School of Medicine, Department for Cardiovascular Diseases, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia.
authors.forename: Bosko
authors.initials: B
authors.lastname: Skoric
authors.affiliation: University of Zagreb School of Medicine, Department for Laboratory Diagnostics, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia.
authors.forename: Lana
authors.initials: L
authors.lastname: Ganoci
authors.affiliation: University of Zagreb School of Medicine, Department for Cardiac Surgery, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia.
authors.forename: Mate
authors.initials: M
authors.lastname: Petricevic
authors.affiliation: University of Zagreb School of Medicine, Department for Cardiovascular Diseases, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia.
authors.forename: Miroslav
authors.initials: M
authors.lastname: Krpan
authors.affiliation: University of Zagreb School of Medicine, Department for Cardiovascular Diseases, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia.
authors.forename: Marijan
authors.initials: M
authors.lastname: Pasalic
authors.affiliation: University of Zagreb School of Medicine, Department for Cardiovascular Diseases, University Hospital Center Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia.
authors.forename: Davor
authors.initials: D
authors.lastname: Milicic
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood / Q000188:drug therapy / Q000235:genetics*; D000368:Aged; D001792:Blood Platelets / Q000502:physiology*; D000077144:Clopidogrel; D065731:Cytochrome P-450 CYP2C19 / Q000235:genetics* / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D010979:Platelet Function Tests; D016032:Randomized Controlled Trials as Topic; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D016896:Treatment Outcome
chemical_list: D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D065731:Cytochrome P-450 CYP2C19; D013988:Ticlopidine
keywords: Acute coronary syndrome; CYP2C19; Clopidogrel; Pharmacogenetics; Platelet function testing; Tailoring therapy