title: Epidemiology of melanoma in the South of Brazil: study of a city in the Vale do Itajaí from 1999 to 2013.
abstract: BACKGROUND
  Cutaneous melanoma is a highly aggressive malignancy with increasing incidence worldwide. The southern Brazilian state of Santa Catarina has one of the highest incidence rates of melanoma in the country.
  
  
  OBJECTIVE
  To evaluate the epidemiological profile of melanoma patients in a southern city of Brazil.
  
  
  METHODS
  a cross-sectional retrospective study was conducted, aiming to detect the clinical and histopathological characteristics of cutaneous melanoma diagnosed in the city of Brusque - SC, between 1999 and 2013.
  
  
  RESULTS
  A total of 213 cases in 212 individuals were studied. More than 50% of the patients were females (p< 0.05). The trunk was the most commonly affected site (p< 0.05), followed by the upper limbs. Nodular and superficial spreading melanomas were the most commonly detected in histological analyses. They did not differ statistically in frequency, but were more prevalent than other histopathological subtypes (p< 0.05). There was no statistically significant difference between invasive and noninvasive melanomas (p= 0.2441). Among the invasive melanomas, those with Breslow thicknesses < 1 mm and between 1-2mm were more prevalent (p< 0.05).
  
  
  CONCLUSIONS
  In this study we found a higher frequency of melanomas in female patients and patients aged over 51. The trunk was the most commonly affected site. Nodular and superficial spreading melanomas prevailed. Among invasive melanomas, those with Breslow thicknesses < 2 mm were the most frequent. This paper highlights the epidemiological profile of melanoma patients in the city and may help to identify and aid in the follow-up of those who are most likely to present the disease.
authors.affiliation: Brusque, Brusque, SC, Brazil.
authors.forename: Adma Silva de
authors.initials: AS
authors.lastname: Lima
authors.affiliation: Fundação Regional de Blumenau, Blumenau, SC, Brazil.
authors.forename: Carlos Efrain
authors.initials: CE
authors.lastname: Stein
authors.affiliation: Vitalab, Brusque, SC, Brazil.
authors.forename: Karla Patricia
authors.initials: KP
authors.lastname: Casemiro
authors.affiliation: Hospital Santo Antonio, Blumenau, SC, Brazil.
authors.forename: Rodrigo Kraft
authors.initials: RK
authors.lastname: Rovere
mesh_terms: D000328:Adult; D017677:Age Distribution; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000453:epidemiology* / Q000473:pathology; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D012737:Sex Factors; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000473:pathology
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