title: Preparation and application of micro/nanoparticles based on natural polysaccharides.
abstract: Polysaccharides have attracted more and more attentions and been recognized to be the most promising materials in recent years because of their outstanding merits such as easily available, non-toxic, biocompatible, biodegradable, and easily modified. Considerable research efforts have been directed toward developing polysaccharides-based micro/nanoparticles (PM/NPs). The new major studies of PM/NPs over the past few years are outlined in this review. Methods of preparation, including self-assembly, ionic-gelation, complex coacervation, emulsification, and desolvation method and some others, are summarized. Different applications of PM/NPs in the field of drug-delivery system are highlighted. Besides, another novel application of PM/NPs that are used as emulsifiers to stabilize Pickering emulsion is also introduced. These environmental-friendly particle emulsifiers have received reasonable attention due to their novel applications, especially in food, cosmetics, and pharmaceutics. From literature surveys, we realized that studies on PM/NP systems for different applications have increased rapidly. Hence, the present review is timely.
authors.affiliation: School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China. Electronic address: jsyang@yzu.edu.cn.
authors.forename: Jisheng
authors.initials: J
authors.lastname: Yang
authors.affiliation: School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
authors.forename: Suya
authors.initials: S
authors.lastname: Han
authors.affiliation: School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
authors.forename: Haicheng
authors.initials: H
authors.lastname: Zheng
authors.affiliation: School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
authors.forename: Hongbiao
authors.initials: H
authors.lastname: Dong
authors.affiliation: School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China.
authors.forename: Jiubing
authors.initials: J
authors.lastname: Liu
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems; D004655:Emulsions; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry*
chemical_list: D004655:Emulsions; D011134:Polysaccharides
keywords: Micro/nanoparticles; Pharmaceutics; Pickering emulsions; Polysaccharides