title: Orofacial granulomatosis affecting lip and gingiva in a 15-year-old patient: A rare case report.
abstract: Orofacial granulomatosis (OFG) is a rare disorder affecting the orofacial region, and clinically characterized by diffuse, nontender, soft to firm, painless swelling restricted to one or both lips and intraoral sites such as tongue, gingiva and buccal mucosa. Histologically, OFG is characterized by noncaseating granulomatous inflammation. The early diagnosis of OFG is essential for the better prognosis of the lesion. Delay in diagnosis of OFG results into formation of indurated and permanent swelling of the lip that not only compromises esthetic appearance but also causes impairment in function such as speaking and eating. Early diagnosis of OFG is challenging to the health care professionals due to clinical and histological resemblance to other chronic granulomatous disorders. Thus, dentists may act as a first person to diagnose the lesion and play an important role in the multidisciplinary treatment of granulomatous disorders. Here, we present a case of OFG affecting lips and gingiva in a 15-year-old patient without any identifiable systemic or local causes.
authors.affiliation: Department of Periodontics, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
authors.forename: Monika
authors.initials: M
authors.lastname: Bansal
authors.affiliation: Department of Periodontics, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
authors.forename: Nootan
authors.initials: N
authors.lastname: Singh
authors.affiliation: Department of Pathology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
authors.forename: Shashikant
authors.initials: S
authors.lastname: Patne
authors.affiliation: Department of Dermatology and Venerology Faculty of Modern Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
authors.forename: Satyendra Kumar
authors.initials: SK
authors.lastname: Singh
keywords: Corticosteroid therapy; gingival enlargement; noncaseating granulomatous inflammation; orofacial granulomatosis
references.citation: J Indian Soc Pedod Prev Dent. 2012 Jul-Sep;30(3):262-6
references.pmid: 23263433
references.citation: Arch Dermatol. 1993 Apr;129(4):477-80
references.pmid: 8466220
references.citation: J Oral Maxillofac Pathol. 2012 Sep;16(3):432-4
references.pmid: 23248481
references.citation: J Can Dent Assoc. 2006 May;72(4):325-9
references.pmid: 16684476
references.citation: J Indian Soc Periodontol. 2012 Jul;16(3):469-74
references.pmid: 23162350
references.citation: Q J Med. 1985 Jan;54(213):101-13
references.pmid: 3975343
references.citation: J Am Acad Dermatol. 2004 Aug;51(2):265-8
references.pmid: 15280846