title: Chemometric analyses for the characterization of raw and processed seeds of Descurainia sophia (L.) based on HPLC fingerprints.
abstract: The seeds of Descurainia sophia (L.) (short for DSS below), with a long history of medicinal utilization in China, have attracted the attention of many Chinese medicine practitioners for the potent efficacy. In the present study, the raw and processed DSS were differentiated by several chemometrics methods based on HPLC fingerprints. Moreover, peaks which were mainly responsible for the differentiation between raw and roasted DSS were found. Therefore, the method of the chromatographic fingerprints combined with multivariate statistical analysis was effective and reasonable in orientating chemical constituents which were mainly responsible for the differentiation between raw and roasted materials, thus shedding light on illustrating the processing mechanism. What's more, this method can also be applied in the identification of authenticity.
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China.
authors.forename: Xidan
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China.
authors.forename: Liying
authors.initials: L
authors.lastname: Tang
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China.
authors.forename: Hongwei
authors.initials: H
authors.lastname: Wu
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China.
authors.forename: Guohong
authors.initials: G
authors.lastname: Zhou
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Wang
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China.
authors.forename: Zhenzhen
authors.initials: Z
authors.lastname: Kou
authors.affiliation: Department of Chinese Medicine, Nanyang Medical College, Nanyang, Henan 473000, China.
authors.forename: Shunxin
authors.initials: S
authors.lastname: Li
authors.affiliation: Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China. Electronic address: wangzhuju@sina.com.
authors.forename: Zhuju
authors.initials: Z
authors.lastname: Wang
mesh_terms: D019607:Brassicaceae / Q000737:chemistry*; D002681:China; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D015999:Multivariate Analysis; D012639:Seeds / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal
keywords: Descurainia sophia (L.); High-performance liquid chromatography with diode array detector fingerprints; Multivariate statistical analysis; Plantago depressa Willd; Processing mechanism