title: Bioactivity and chemical constituents of the essential oil from Dendranthema indicum (L.) Des Moul. against two stored insects.
abstract: Dendranthema indicum (L.) Des Moul. is a perennial herb commonly used as a traditional Chinese medicine for a long time. In this work, we took Dendranthema indicum as a target plant and two stored insects which include Tribolium castaneum and Stegobium paniceum adults as target insects. Essential oil obtained from Dendranthema indicum was analyzed by gas chromatography-mass spectrometry (GC-MS). A total of 31 components representing 92.44% of the oil were identified and the main compounds were found to be chamazulene (15.93%), β-caryophyllene (13.78%), germacrene D (9.11%), and b-cis-farnesene (6.59%). With a further isolation, three constituents were obtained from the essential oil and identified as chamazulene, β-caryophyllene and eucalyptol. Significantly, in the progress of assay, it showed that the essential oil and chamazulene exhibited stronger insecticidal and repellent activities against Stegobium paniceum than Tribolium castaneum. The results indicate that additional to its traditional use as Chinese medicinal herb, the essential oil of Dendranthema indicum aerial parts and isolated compounds have potential to be developed into natural insecticides or repellents for control of insects in stored grains.
authors.affiliation: Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Beijing Normal University.
authors.forename: Wen-Juan
authors.initials: WJ
authors.lastname: Zhang
authors.forename: Chun-Xue
authors.initials: CX
authors.lastname: You
authors.forename: Kai
authors.initials: K
authors.lastname: Yang
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.forename: Yang
authors.initials: Y
authors.lastname: Su
authors.forename: Zhu-Feng
authors.initials: ZF
authors.lastname: Geng
authors.forename: Shu-Shan
authors.initials: SS
authors.lastname: Du
authors.forename: Cheng-Fang
authors.initials: CF
authors.lastname: Wang
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Deng
authors.forename: Yong-Yan
authors.initials: YY
authors.lastname: Wang
mesh_terms: D000818:Animals; D019659:Asteraceae / Q000737:chemistry*; D052176:Azulenes / Q000302:isolation & purification / Q000494:pharmacology; D001517:Coleoptera / Q000187:drug effects*; D003511:Cyclohexanols / Q000302:isolation & purification; D004365:Drugs, Chinese Herbal; D002523:Edible Grain / Q000469:parasitology; D000077591:Eucalyptol; D061353:Food Storage; D008401:Gas Chromatography-Mass Spectrometry; D007302:Insect Repellents / Q000032:analysis / Q000494:pharmacology; D007306:Insecticides / Q000032:analysis / Q000494:pharmacology; D039821:Monoterpenes / Q000302:isolation & purification; D009822:Oils, Volatile / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology*; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes / Q000302:isolation & purification; D045788:Sesquiterpenes, Germacrane / Q000302:isolation & purification
chemical_list: D052176:Azulenes; D003511:Cyclohexanols; D004365:Drugs, Chinese Herbal; D007302:Insect Repellents; D007306:Insecticides; D039821:Monoterpenes; D009822:Oils, Volatile; D000081223:Polycyclic Sesquiterpenes; D012717:Sesquiterpenes; D045788:Sesquiterpenes, Germacrane; C024714:caryophyllene; D000077591:Eucalyptol; C027259:germacrene D; C013872:chamazulene