title: [Intrauterine growth retardation in Peru: stressors and perinatal outcomes Hospital Ministry of Health].
abstract: OBJECTIVE
  To determine the incidence, stressors and perinatal outcomes of intrauterine growth retardation in the hospitals of the Ministry of Health of Peru.
  
  
  METHODS
  Cross-sectional, analytical, case-control study of 9777 infants with intrauterine growth retardation (IUGR) in 29 hospitals of the Ministry of Health of Peru in 2010. The Peruvian intrauterine growth curve was used for the diagnosis of IUGR. IUGR newborns (cases) and newborns appropriate for gestational age (controls) were compared using the odds ratio (OR) with a confidence interval of 95%.
  
  
  RESULTS
  The incidence of IUGR was 10.1%. The incidence by region was: 8.1% Coast, 11.8% Selva and Sierra 14.6%. The frequency of stress factors of IUGR were: nutrition (92%), psychological (84.8%), social (53%), anatomical (63.6%), toxic/environmental (52.9%), vascular (29,8%), infection (14.1%) and metabolic (0.3%). The newborn with IUGR had higher perinatal morbidity (OR=2,1) and mortality (OR=3.5).
  
  
  CONCLUSIONS
  The healthy fetus is the result of a balance between stress factors and the adaptive response of the mother and fetus. When the response of physiological adaptation is overcome by stress factors, IUGR occurs.The political, psychological, nutritional and medical intervention before 12 weeks of gestation has the potential to change the harmful effects of all human stress factors that affect fetal growth.
authors.forename: Manuel
authors.initials: M
authors.lastname: Ticona-Rendón
authors.forename: Percy
authors.initials: P
authors.lastname: Pacora-Portella
authors.forename: Diana
authors.initials: D
authors.lastname: Huanco-Apaza
authors.forename: Maricarmen
authors.initials: M
authors.lastname: Ticona-Vildoso
mesh_terms: D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D005317:Fetal Growth Retardation / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D010568:Peru; D011247:Pregnancy; D011256:Pregnancy Outcome; D013312:Stress, Physiological; D013315:Stress, Psychological / Q000150:complications*