title: [Peroxyredoxins as multifunctional enzymes].
abstract: Peroxiredoxins are evolutionarily ancient, but relatively recently discovered group of seleniumindependent peroxidases. Peroxiredoxins protect cells from various peroxides and play an important role in maintaining the oxidation-reduction homeostasis. Moreover, they are involved in many cellular processes that are not related to peroxidase activity. Here, recent data on the structure and function of peroxiredoxins, regulation of gene expression and activity of different peroxiredoxins are considered.
authors.forename: M G
authors.initials: MG
authors.lastname: Sharapov
authors.forename: V K
authors.initials: VK
authors.lastname: Ravin
authors.forename: V I
authors.initials: VI
authors.lastname: Novoselov
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001105:Archaea / Q000201:enzymology; D015971:Gene Expression Regulation, Enzymologic; D007313:Insecta / Q000201:enzymology; D008322:Mammals / Q000378:metabolism; D008969:Molecular Sequence Data; D064251:Multifunctional Enzymes / Q000378:metabolism; D010084:Oxidation-Reduction; D054464:Peroxiredoxins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000201:enzymology; D011387:Prokaryotic Cells / Q000201:enzymology; D011487:Protein Conformation; D011499:Protein Processing, Post-Translational; D017386:Sequence Homology, Amino Acid; D015003:Yeasts / Q000201:enzymology
chemical_list: D064251:Multifunctional Enzymes; D054464:Peroxiredoxins