title: Multilayer flow modulator stent technology: a treatment revolution for US patients?
abstract: Thoracoabdominal aortic repair is a high-risk procedure in most experienced centers, not only because of anatomical complexity but also due to the fragility of the patients in whom these aneurysms occur. Such repairs are complex, time-consuming and impose a systemic injury upon the patients, regardless of whether the repair is performed by open surgery or via a fenestrated/branched technique. The substantive risks associated with such repairs include death, dialysis and paralysis. The multilayer flow modulator (MFM) is a disruptive technology which promises a minimally invasive reproducible treatment option, with clinical results demonstrating physiological modulation of the aortic sac with abolition of spinal injury. The mode of action of MFM forces us to completely rethink aneurysm pathogenesis and, consequently, it has been met with much cynicism. We aim to uncloak some of the mystery surrounding the MFM, clarify its mode of action and explore the truth behind its clinical effectiveness.
authors.affiliation: Department of Vascular and Endovascular Surgery, Western Vascular Institute, Galway University Hospital, National University of Ireland, Galway, Ireland.
authors.forename: Sherif
authors.initials: S
authors.lastname: Sultan
authors.forename: Niamh
authors.initials: N
authors.lastname: Hynes
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D001027:Aortography; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation*; D002986:Clinical Trials as Topic; D057510:Endovascular Procedures / Q000295:instrumentation*; D006801:Humans; D011474:Prosthesis Design; D015607:Stents
keywords: aortic dissection; disruptive technology; hemodynamics; multilayer flow modulator; thoracoabdominal aortic aneurysm