title: Stroke mortality and its predictors in a Nigerian teaching hospital.
abstract: BACKGROUND
  Stroke is the third leading cause of death worldwide. Stroke mortality has been noted to be higher in blacks in biracial studies. There have been few studies on stroke mortality and its predictors in Nigeria. This study examines mortality of stroke and its predictors in a Northern Nigerian teaching hospital.
  
  
  METHODS
  This was a prospective study that was carried out at Jos University Teaching Hospital in Nigeria. One hundred and twenty stroke patients admitted into the medical wards within one year were assessed. Demographic data was recorded. Patients were examined and ancillary investigations were carried out. The deaths and predictors were recorded. Multivariate logistic regression was used to identify independent predictors of mortality.
  
  
  RESULTS
  There were one hundred and twenty participants. Forty two (35%), patients died. Most (76.2%) deaths occurred within the first week. Predictors of mortality on univariate analysis were age ≥ 60 years, male sex, loss of consciousness, high NIHSS score (≥16), the presence of co-morbid conditions and presence of complications. On multivariate analysis, the predictors of mortality were the presence of co-morbid conditions, GCS<10 and high NIHSS score.
  
  
  CONCLUSIONS
  Stroke mortality was quite high in this study. Predictors of mortality were the indices of severity and the presence of co-morbid conditions.
authors.affiliation: University of Uyo Teaching Hospital, Internal Medicine.
authors.forename: Bertha
authors.initials: B
authors.lastname: Ekeh
authors.affiliation: University College, Ibadan, Internal Medicine.
authors.forename: Adesola
authors.initials: A
authors.lastname: Ogunniyi
authors.affiliation: Jos University Teaching Hospital, Internal Medicine.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Isamade
authors.affiliation: University of Uyo Teaching Hospital, Internal Medicine.
authors.forename: Udeme
authors.initials: U
authors.lastname: Ekrikpo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006784:Hospitals, Teaching; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D020300:Intracranial Hemorrhages / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009549:Nigeria / Q000453:epidemiology; D011237:Predictive Value of Tests; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D020521:Stroke / Q000175:diagnosis / Q000401:mortality*; D013997:Time Factors
keywords: Co-morbid conditions; Level of consciousness; Mortality; National Institute of Health Stroke Scale (NIHSS score); Predictors; Stroke
references.citation: Trop Doct. 2007 Jul;37(3):186-8
references.pmid: 17716518
references.citation: J Stroke Cerebrovasc Dis. 2007 Jan-Feb;16(1):34-9
references.pmid: 17689390
references.citation: Med Trop (Mars). 2007 Dec;67(6):596-600
references.pmid: 18300522
references.citation: Stroke. 2008 Aug;39(8):2318-24
references.pmid: 18566303
references.citation: J Coll Physicians Surg Pak. 2008 Dec;18(12):755-8
references.pmid: 19032888
references.citation: Lancet Neurol. 2009 Apr;8(4):355-69
references.pmid: 19233729
references.citation: Lancet Neurol. 2011 Apr;10(4):357-71
references.pmid: 21247806
references.citation: Ann Afr Med. 2011 Apr-Jun;10(2):80-5
references.pmid: 21691011
references.citation: Rev Epidemiol Sante Publique. 2000 Jan;48(1):31-9
references.pmid: 10740083
references.citation: Stroke. 2004 Feb;35(2):426-31
references.pmid: 14757893
references.citation: Bull World Health Organ. 2004 Jul;82(7):503-8
references.pmid: 15500283
references.citation: Clin Exp Neurol. 1992;29:117-28
references.pmid: 1343856
references.citation: N Engl J Med. 1995 Dec 14;333(24):1581-7
references.pmid: 7477192
references.citation: Neurology. 1999 Jul 13;53(1):126-31
references.pmid: 10408548
references.citation: Arch Neurol. 2005 Mar;62(3):393-7
references.pmid: 15767504
references.citation: Stroke. 2005 Jul;36(7):1388-93
references.pmid: 15947255
references.citation: Lancet Neurol. 2007 Mar;6(3):269-78
references.pmid: 17303533
references.citation: J R Soc Med. 2007 Nov;100(11):503-7
references.pmid: 18048707