title: Predicting N2pc from anticipatory HbO activity during sustained visuospatial attention: a concurrent fNIRS-ERP study.
abstract: Understanding the properties of attentional control, along with the neural mechanisms subserving them, has long invited intense scrutiny in research groups. However, it has not been demonstrated how the top-down anticipatory hemodynamic activation influences the subsequent attentional processing of targets and distractors. Here, with concurrent fNIRS-ERP recording, we explored the potential contribution of anticipatory oxygenated hemoglobin (HbO) based brain activity to attentional control by examining how HbO influences the subsequent ERP N2pc components assumed to reflect attentional selection. We found that expecting a target led to a larger increase of preparatory HbO response over the visual cortex contralateral to the upcoming target, which was positively correlated with the subsequent target-evoked N2pc amplitude. Further, anticipation concerning the presence of a competing distractor resulted in large and prolonged preparatory HbO signals in the visual cortex contralateral to the distractor, indicating that the salient distractor might be actively suppressed by preparatory top-down attentional control. However, the pre-suppressed distractor still captured part of the attention in the subsequent visual search as revealed by a decrease in the N2pc amplitude, and such a distraction effect on N2pc was negatively correlated with preparatory HbO enhancement contralateral to the anticipated distractor. Overall, each individuals attentional shift to the target and resistance to the distractor measured by ERP is predictable in advance via anticipatory hemodynamic activity in the visual cortex measured by fNIRS.
authors.affiliation: State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Huang
authors.affiliation: State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.affiliation: Brain and Cognition Laboratory, Department of Psychology, Sun Yat-Sen University, Guangzhou 510275, China.
authors.forename: Yulong
authors.initials: Y
authors.lastname: Ding
authors.affiliation: State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China; Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing 100875, China.
authors.forename: Haijing
authors.initials: H
authors.lastname: Niu
authors.affiliation: Department of Bioengineering, The University of Texas at Arlington, Arlington, TX, USA.
authors.forename: Fenghua
authors.initials: F
authors.lastname: Tian
authors.affiliation: Department of Bioengineering, The University of Texas at Arlington, Arlington, TX, USA.
authors.forename: Hanli
authors.initials: H
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China; Center for Collaboration and Innovation in Brain and Learning Sciences, Beijing Normal University, Beijing 100875, China. Electronic address: songyan@bnu.edu.cn.
authors.forename: Yan
authors.initials: Y
authors.lastname: Song
mesh_terms: D001288:Attention / Q000502:physiology; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D008297:Male; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology; D013028:Space Perception / Q000502:physiology*; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D014793:Visual Cortex / Q000502:physiology; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult
chemical_list: D006454:Hemoglobins
keywords: Anticipation; Event-related potential; Functional near-infrared spectroscopy; Hemoglobin; Spatial attention