title: Multimodal management of a pediatric cervical yolk sac tumor.
abstract: Even though vaginal bleeding is an unusual clinical presentation in infants and young children, thorough evaluation by the pediatric urologist requires the recognition and knowledge of less-common conditions, including malignancy. Extragonadal germ cell tumors are rare in children aged <15 years, representing approximately 1% of all cancers. Because of the close collaboration between pediatric oncologists and pediatric urologists, a multidisciplinary approach to the management and treatment of these tumors includes chemotherapy and surgical resection, aiming for fertility preservation when possible. We present a 10-month-old infant with a cervical or uterine germ cell tumor and the challenges found during her treatment.
authors.affiliation: Department of Urology, Louisiana State University Health Sciences Center, New Orleans, LA.
authors.forename: Amanda F
authors.initials: AF
authors.lastname: Saltzman
authors.affiliation: Department of Urology, Louisiana State University Health Sciences Center, New Orleans, LA.
authors.forename: Jessie R R
authors.initials: JRR
authors.lastname: Gills
authors.affiliation: Department of Hematology/Oncology, Children's Hospital of New Orleans, New Orleans, LA.
authors.forename: Dana M
authors.initials: DM
authors.lastname: LeBlanc
authors.affiliation: Department of Hematology/Oncology, Children's Hospital of New Orleans, New Orleans, LA.
authors.forename: Maria C
authors.initials: MC
authors.lastname: Velez
authors.affiliation: Department of Pathology, Children's Hospital of New Orleans, New Orleans, LA.
authors.forename: Randall D
authors.initials: RD
authors.lastname: Craver
authors.affiliation: Department of Urology, Louisiana State University Health Sciences Center, New Orleans, LA; Department of Urology, Children's Hospital of New Orleans, New Orleans, LA. Electronic address: croth@lsuhsc.edu.
authors.forename: Christopher C
authors.initials: CC
authors.lastname: Roth
mesh_terms: D003131:Combined Modality Therapy; D018240:Endodermal Sinus Tumor / Q000628:therapy*; D005260:Female; D006801:Humans; D007223:Infant; D009373:Neoplasms, Germ Cell and Embryonal / Q000628:therapy*; D014594:Uterine Neoplasms / Q000628:therapy*