title: Comparative evaluation of antimicrobial efficacy of QMix™ 2 in 1, sodium hypochlorite, and chlorhexidine against Enterococcus faecalis and Candida albicans.
abstract: OBJECTIVE
  The aim of this study is to compare the antimicrobial efficacy of QMix™ 2 in 1, sodium hypochlorite (NaOCl), and chlorhexidine (CHX) against Enterococcus faecalis and Candida albicans.
  
  
  METHODS
  Eighty freshly extracted, single-rooted human mandibular premolar teeth were instrumented and autoclaved. Samples were divided into two groups of 40 teeth each based on the type of microorganism used. Group I was inoculated with E. faecalis and Group II with C. albicans and incubated for 3 days. Each group was subdivided into four subgroups based on the type of irrigant used. Group IA, IIA, 5.25% NaOCl; Group IB, IIB, 2% CHX; Group IC, IIC, QMix™ 2 in 1; and Group ID, IID, 0.9% saline (the control group). Ten microliters of the sample from each canal was taken and was placed on Brain Heart Infusion agar and Sabouraud dextrose agar. The plates were incubated at 37°C for 24 h and colony forming units (CFUs) that were grown were counted. Data was analyzed with analysis of variance (ANOVA) followed by post-hoc Games-Howell test.
  
  
  RESULTS
  The greatest antimicrobial effects were observed in samples treated with QMix™ 2 in 1 (P < 0.001). No statistical significant difference was found between 5.25% NaOCl and 2% CHX (P > 0.001) against E. faecalis and C. albicans.
  
  
  CONCLUSIONS
  QMix™ 2 in 1 demonstrated significant antimicrobial efficacy against E. faecalis and C. albicans.
authors.affiliation: Department of Conservative Dentistry and Endodontics, Mamata Dental College, Khammam, Andhra Pradesh, India.
authors.forename: Soujanya
authors.initials: S
authors.lastname: Elakanti
authors.affiliation: Oral Pathology and Microbiology, Mamata Dental College, Khammam, Andhra Pradesh, India.
authors.forename: Gayathri
authors.initials: G
authors.lastname: Cherukuri
authors.affiliation: Oral Pathology and Microbiology, Mamata Dental College, Khammam, Andhra Pradesh, India.
authors.forename: Venkateswara G
authors.initials: VG
authors.lastname: Rao
authors.affiliation: Department of Conservative Dentistry and Endodontics, Mamata Dental College, Khammam, Andhra Pradesh, India.
authors.forename: Veeramachaneni
authors.initials: V
authors.lastname: Chandrasekhar
authors.affiliation: Department of Conservative Dentistry and Endodontics, Mamata Dental College, Khammam, Andhra Pradesh, India.
authors.forename: Anitha S
authors.initials: AS
authors.lastname: Rao
authors.affiliation: Department of Conservative Dentistry and Endodontics, Mamata Dental College, Khammam, Andhra Pradesh, India.
authors.forename: Muralidhar
authors.initials: M
authors.lastname: Tummala
keywords: Candida albicans; Enterococcus faecalis; QMix™ 2 in 1; chlorhexidine; sodium hypochlorite
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