title: Survival rates according to barcelona clinic liver cancer sub-staging system after transarterial embolization for intermediate hepatocellular carcinoma.
abstract: OBJECTIVE
  To investigate the survival rates after transarterial embolization (TAE).
  
  
  METHODS
  One hundred third six hepatocellular carcinoma (HCC) patients [90 barcelona clinic liver cancer (BCLC) B] were submitted to TAE between August 2008 and December 2013 in a single center were retrospectively studied. TAE was performed via superselective catheterization followed by embolization with polyvinyl alcohol or microspheres. The date of the first embolization until death or the last follow-up date was used for the assessment of survival. The survival rates were calculated using the Kaplan-Meier method, and the groups were compared using the log-rank test.
  
  
  RESULTS
  The overall mean survival was 35.8 mo (95%CI: 25.1-52.0). The survival rates of the BCLC A patients (33.7%) were 98.9%, 79.0% and 58.0% at 12, 24 and 36 mo, respectively, and the mean survival was 38.1 mo (95%CI: 27.5-52.0). The survival rates of the BCLC B patients (66.2%) were 89.0%, 69.0% and 49.5% at 12, 24 and 36 mo, respectively, and the mean survival was 29.0 mo (95%CI: 17.2-34). The survival rates according to the BCLC B sub-staging showed significant differences between the groups, with mean survival rates in the B1, B2, B3 and B4 groups of 33.5 mo (95%CI: 32.8-34.3), 28.6 mo (95%CI: 27.5-29.8), 19.0 mo (95%CI: 17.2-20.9) and 13 mo, respectively (P = 0.013).
  
  
  CONCLUSIONS
  The BCLC sub-staging system could add additional prognosis information for post-embolization survival rates in HCC patients.
authors.affiliation: Leandro Armani Scaffaro, Radiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, Brazil.
authors.forename: Leandro Armani
authors.initials: LA
authors.lastname: Scaffaro
authors.affiliation: Leandro Armani Scaffaro, Radiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, Brazil.
authors.forename: Steffan Frosi
authors.initials: SF
authors.lastname: Stella
authors.affiliation: Leandro Armani Scaffaro, Radiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, Brazil.
authors.forename: Mario Reis
authors.initials: MR
authors.lastname: Alvares-Da-Silva
authors.affiliation: Leandro Armani Scaffaro, Radiology Division, Hospital de Clínicas de Porto Alegre, Porto Alegre 90035-903, Brazil.
authors.forename: Cleber Dario Pinto
authors.initials: CD
authors.lastname: Kruel
keywords: Barcelona clinic liver cancer; Hepatocellular carcinoma; Subclassification; Transarterial embolization
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