title: Recurrent seizures, mental retardation and extensive brain calcinosis related to delayed diagnosis of hypoparathyroidism in an adolescent boy.
abstract: Reports of adolescent patients presenting with intractable seizures and mental retardation secondary to idiopathic hypothyroidism are uncommon in the literature. In this case, we report a 17-year-old boy who developed recurrent seizures, mental retardation and extensive brain calcinosis related to delayed diagnosis of hypoparathyroidism. Hypoparathyroidism can be easily missed in children and adolescents, and may lead to irreversible neurologic sequelae. This case highlights the need to consider hypocalcemia in any patient with uncontrolled seizures.
authors.affiliation: Department of Pediatric Neurology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
authors.forename: Tae-Hoon
authors.initials: TH
authors.lastname: Eom
authors.affiliation: Department of Pediatric Neurology, College of Medicine, The Catholic University of Korea, 271 Cheonbo Street, Uijeongbu, Gyeonggi-do 480-717, Republic of Korea. Electronic address: pedkyh@catholic.ac.kr.
authors.forename: Young-Hoon
authors.initials: YH
authors.lastname: Kim
authors.affiliation: Department of Endocrinology, Inje University Sanggye Paik Hospital, Seoul, Republic of Korea.
authors.forename: Jung-Min
authors.initials: JM
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology*; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis; D002114:Calcinosis / Q000175:diagnosis* / Q000209:etiology; D057210:Delayed Diagnosis; D006801:Humans; D006996:Hypocalcemia / Q000150:complications / Q000175:diagnosis; D007011:Hypoparathyroidism / Q000150:complications / Q000175:diagnosis*; D008607:Intellectual Disability / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D012640:Seizures / Q000175:diagnosis* / Q000209:etiology
keywords: Brain calcinosis; Hypocalcemia; Hypoparathyroidism; Mental retardation; Seizures