title: Introduction.
authors.forename: Jaffer A
authors.initials: JA
authors.lastname: Ajani
authors.forename: Shumei
authors.initials: S
authors.lastname: Song
authors.forename: Howard S
authors.initials: HS
authors.lastname: Hochster
authors.forename: Ira B
authors.initials: IB
authors.lastname: Steinberg
mesh_terms: D006801:Humans; D009362:Neoplasm Metastasis / Q000473:pathology; D009369:Neoplasms / Q000378:metabolism / Q000473:pathology*; D014411:Neoplastic Stem Cells / Q000378:metabolism / Q000473:pathology*; D015398:Signal Transduction; D059016:Tumor Microenvironment