title: Processing deficits for familiar and novel faces in patients with left posterior fusiform lesions.
abstract: Pure alexia (PA) arises from damage to the left posterior fusiform gyrus (pFG) and the striking reading disorder that defines this condition has meant that such patients are often cited as evidence for the specialisation of this region to processing of written words. There is, however, an alternative view that suggests this region is devoted to processing of high acuity foveal input, which is particularly salient for complex visual stimuli like letter strings. Previous reports have highlighted disrupted processing of non-linguistic visual stimuli after damage to the left pFG, both for familiar and unfamiliar objects and also for novel faces. This study explored the nature of face processing deficits in patients with left pFG damage. Identification of famous faces was found to be compromised in both expressive and receptive tasks. Discrimination of novel faces was also impaired, particularly for those that varied in terms of second-order spacing information, and this deficit was most apparent for the patients with the more severe reading deficits. Interestingly, discrimination of faces that varied in terms of feature identity was considerably better in these patients and it was performance in this condition that was related to the size of the length effects shown in reading. This finding complements functional imaging studies showing left pFG activation for faces varying only in spacing and frontal activation for faces varying only on features. These results suggest that the sequential part-based processing strategy that promotes the length effect in the reading of these patients also allows them to discriminate between faces on the basis of feature identity, but processing of second-order configural information is most compromised due to their left pFG lesion. This study supports a view in which the left pFG is specialised for processing of high acuity foveal visual information that supports processing of both words and faces.
authors.affiliation: Research Centre in Brain and Behaviour, Liverpool John Moores University, UK.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Roberts
authors.affiliation: Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, UK.
authors.forename: Matthew A
authors.initials: MA
authors.lastname: Lambon Ralph
authors.affiliation: Department of Speech Pathology and Audiology, University of Alberta, Canada.
authors.forename: Esther
authors.initials: E
authors.lastname: Kim
authors.affiliation: Bilingual Aphasia Lab, School of Psychology, Bangor University, UK.
authors.forename: Marie-Josephe
authors.initials: MJ
authors.lastname: Tainturier
authors.affiliation: Department of Speech, Language, and Hearing Sciences, University of Arizona, USA.
authors.forename: Pelagie M
authors.initials: PM
authors.lastname: Beeson
authors.affiliation: Department of Neurology, University of Arizona, USA; Neurology Section, Southern Arizona VA Health Care System, Tucson, AZ, USA.
authors.forename: Steven Z
authors.initials: SZ
authors.lastname: Rapcsak
authors.affiliation: Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, UK. Electronic address: anna.woollams@manchester.ac.uk.
authors.forename: Anna M
authors.initials: AM
authors.lastname: Woollams
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005145:Face / Q000503:physiopathology; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010364:Pattern Recognition, Visual / Q000502:physiology; D010468:Perceptual Disorders / Q000209:etiology / Q000503:physiopathology*; D020521:Stroke / Q000209:etiology / Q000503:physiopathology; D013702:Temporal Lobe / Q000503:physiopathology*; D014796:Visual Perception / Q000502:physiology
keywords: Face recognition; Posterior fusiform gyrus; Pure alexia; Ventral occipito-temporal cortex; Word recognition
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