title: Reenvisioning Clinical Science: Unifying the Discipline to Improve the Public Health.
abstract: We present a vision of clinical science, based on a conceptual framework of intervention development endorsed by the Delaware Project. This framework is grounded in an updated stage model that incorporates basic science questions of mechanisms into every stage of clinical science research. The vision presented is intended to unify various aspects of clinical science toward the common goal of developing maximally potent and implementable interventions, while unveiling new avenues of science in which basic and applied goals are of equally high importance. Training in this integrated, translational model may help students learn how to conduct research in every domain of clinical science and at each stage of intervention development. This vision aims to propel the field to fulfill the public health goal of producing implementable and effective treatment and prevention interventions.
authors.affiliation: National Institute on Drug Abuse.
authors.forename: Lisa S
authors.initials: LS
authors.lastname: Onken
authors.affiliation: Yale University.
authors.forename: Kathleen M
authors.initials: KM
authors.lastname: Carroll
authors.affiliation: National Institute of Mental Health.
authors.forename: Varda
authors.initials: V
authors.lastname: Shoham
authors.affiliation: National Institute of Mental Health.
authors.forename: Bruce N
authors.initials: BN
authors.lastname: Cuthbert
authors.affiliation: National Institute of Dental and Craniofacial Research.
authors.forename: Melissa
authors.initials: M
authors.lastname: Riddle
keywords: implementation; intervention development; stage model; translation
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