title: Association between overactive bladder and peri-menopause syndrome: a cross-sectional study of female physicians in China.
abstract: OBJECTIVE
  To determine the detailed association between overactive bladder (OAB) and peri-menopause syndrome (PMpS) in Chinese female physicians of peri-menopausal age.
  
  
  METHODS
  Data for this study were collected by administering questionnaires eliciting general information (peri-menopausal symptoms and OAB status) to middle-aged female physicians, from the directly affiliated three hospitals of Peking University in China. We used the overactive bladder symptom score (OABSS) to verify the symptoms of OAB and the modified Kupperman menopausal index (KMI) to assess PMpS.
  
  
  RESULTS
  Three hundred fifty-one questionnaires were finally evaluated. The average age was 47.1 ± 5.4 years. Overall, 7.4% of respondents had OAB and 22.6% had PMpS. There was a significant positive correlation between the severity of OAB and prevalence of OAB and PMpS. The prevalence of OAB in women with PMpS (KMI > 15) was significantly increased (18.99 vs. 4.44%; P = 0.000). The average OABSS in women with PMpS was 2.67 ± 2.15, compared with 1.46 ± 1.50 in women without PMpS. The average KMI score in women with OAB was 16.04 ± 10.1, compared with 9.50 ± 8.13 in women without OAB (P = 0.000). Multivariate logistic regression analysis results showed that only BMI and PMpS were independent risk factors for OAB.
  
  
  CONCLUSIONS
  In China, female physicians with menopausal symptoms tend to have a higher prevalence of OAB and more severe symptoms of OAB.
authors.affiliation: Department of Urology, Peking University First Hospital and Institute of Urology, Peking University, National Urological Cancer Center, 8 Xishiku Street, Xicheng District, Beijing, 100034, China, yukecc1989@163.com.
authors.forename: Yuke
authors.initials: Y
authors.lastname: Chen
authors.forename: Wei
authors.initials: W
authors.lastname: Yu
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.forename: Jihong
authors.initials: J
authors.lastname: Duan
authors.forename: Yunxiang
authors.initials: Y
authors.lastname: Xiao
authors.forename: Xun
authors.initials: X
authors.lastname: Zhang
authors.forename: Shiliang
authors.initials: S
authors.lastname: Wu
authors.forename: Wenpei
authors.initials: W
authors.lastname: Bai
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005221:Fatigue / Q000453:epidemiology; D005260:Female; D006306:Health Surveys; D019584:Hot Flashes / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D019964:Mood Disorders / Q000453:epidemiology*; D010292:Paresthesia / Q000453:epidemiology; D047648:Perimenopause; D010822:Physicians, Women / Q000706:statistics & numerical data*; D015995:Prevalence; D012307:Risk Factors; D012720:Severity of Illness Index; D012735:Sexual Dysfunction, Physiological / Q000453:epidemiology; D013577:Syndrome; D053201:Urinary Bladder, Overactive / Q000453:epidemiology*
references.citation: Scand J Rheumatol. 1995;24(2):61-3
references.pmid: 7747144
references.citation: BJU Int. 2011 Oct;108(7):1132-8
references.pmid: 21231991
references.citation: Maturitas. 1996 Feb;23(1):85-9
references.pmid: 8861090
references.citation: Int Neurourol J. 2012 Sep;16(3):126-31
references.pmid: 23094218
references.citation: Obstet Gynecol Annu. 1981;10:279-311
references.pmid: 7024875
references.citation: Urology. 2012 Jul;80(1):90-6
references.pmid: 22748867
references.citation: Eur Urol. 2006 Dec;50(6):1306-14; discussion 1314-5
references.pmid: 17049716
references.citation: Neurourol Urodyn. 2013 Mar;32(3):230-7
references.pmid: 22847394
references.citation: Womens Health. 1997 Summer;3(2):103-20
references.pmid: 9332153
references.citation: Maturitas. 2013 Nov;76(3):230-4
references.pmid: 24055286
references.citation: Urology. 2013 Feb;81(2):257-62
references.pmid: 23374774
references.citation: J Urol. 2014 May;191(5):1327-32
references.pmid: 24316095
references.citation: Maturitas. 2013 Jan;74(1):26-30
references.pmid: 23141079
references.citation: Maturitas. 2013 Jan;74(1):84-8
references.pmid: 23149163
references.citation: Soc Sci Med. 2001 Feb;52(3):345-56
references.pmid: 11330770
references.citation: Neurourol Urodyn. 2014 Apr;33(4):387-91
references.pmid: 23765684
references.citation: Maturitas. 2005 Nov-Dec;52(3-4):181-9
references.pmid: 16257609
references.citation: Neurourol Urodyn. 2011 Nov;30(8):1448-55
references.pmid: 21826714
references.citation: Maturitas. 2009 Feb 20;62(2):184-9
references.pmid: 19128903
references.citation: Patient Prefer Adherence. 2013;7:223-9
references.pmid: 23569361
references.citation: Eur Urol. 2005 Aug;48(2):309-13
references.pmid: 16005377
references.citation: J Urol. 2004 Dec;172(6 Pt 2):2570-3
references.pmid: 15538210
references.citation: Maturitas. 2012 Dec;73(4):354-60
references.pmid: 23026018
references.citation: Best Pract Res Clin Obstet Gynaecol. 2009 Feb;23(1):25-32
references.pmid: 19056320
references.citation: Neurourol Urodyn. 2013 Mar;32(3):254-60
references.pmid: 22903277
references.citation: Urology. 2011 Jan;77(1):60-4
references.pmid: 20951412