title: [Molecular diagnostics of non-small cell lung cancer: New markers and technologies].
abstract: Lung cancer is the prototypical tumor entity for the development of new diagnostic and individualized therapeutic strategies based on molecular patient stratification. Developments in this field specifically concentrate on predictive biomarkers for the response to conventional therapeutic agents, novel drugs targeting specific mutations and also new immunomodulatory drugs. The multitude of upcoming new predictive biomarkers requires the development and implementation of efficient test strategies and comprehensive technical methods, specifically when tissue restrictions inherent to lung cancer diagnostics are also taken into account. Novel procedures and technical aspects of these issues are discussed in this review.
authors.affiliation: Institut für Pathologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Warth
authors.forename: V
authors.initials: V
authors.lastname: Endris
authors.forename: M
authors.initials: M
authors.lastname: Kriegsmann
authors.forename: A
authors.initials: A
authors.lastname: Stenzinger
authors.forename: R
authors.initials: R
authors.lastname: Penzel
authors.forename: N
authors.initials: N
authors.lastname: Pfarr
authors.forename: W
authors.initials: W
authors.lastname: Weichert
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology*; D016503:Drug Delivery Systems; D005819:Genetic Markers / Q000235:genetics*; D006801:Humans; D007167:Immunotherapy; D008168:Lung / Q000473:pathology; D025202:Molecular Diagnostic Techniques; D057285:Precision Medicine; D011379:Prognosis
chemical_list: D005819:Genetic Markers
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