title: Meter-long multiblock copolymer microfibers via interfacial bioorthogonal polymerization.
abstract: High-molecular-weight multiblock copolymers are synthesized as robust polymer fibers via interfacial bioorthogonal polymerization employing the rapid cycloaddition of s-tetrazines with strained trans-cyclooctenes. When cell-adhesive peptide is incorporated in the tetrazine monomer, the resulting protein-mimetic polymer fibers provide guidance cues for cell attachment and elongation.
authors.affiliation: Department of Materials Science and Engineering, University of Delaware, Newark, DE, 19716, USA.
authors.forename: Shuang
authors.initials: S
authors.lastname: Liu
authors.forename: Han
authors.initials: H
authors.lastname: Zhang
authors.forename: Roddel A
authors.initials: RA
authors.lastname: Remy
authors.forename: Fei
authors.initials: F
authors.lastname: Deng
authors.forename: Michael E
authors.initials: ME
authors.lastname: Mackay
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Fox
authors.forename: Xinqiao
authors.initials: X
authors.lastname: Jia
mesh_terms: D000818:Animals; D040761:Biomimetic Materials / Q000737:chemistry; D002152:Calorimetry, Differential Scanning; D061565:Cycloaddition Reaction; D034242:Cyclooctanes / Q000737:chemistry; D006573:Heterocyclic Compounds, 1-Ring / Q000737:chemistry; D051379:Mice; D018625:Microscopy, Atomic Force; D018613:Microscopy, Confocal; D041681:NIH 3T3 Cells; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D013696:Temperature
chemical_list: D034242:Cyclooctanes; D006573:Heterocyclic Compounds, 1-Ring; D011108:Polymers
keywords: bioorthogonal; fibers; guidance cues; interfacial polymerization; multiblock copolymer
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