title: Reproducibility of a Standardized Actigraphy Scoring Algorithm for Sleep in a US Hispanic/Latino Population.
abstract: OBJECTIVE
  While actigraphy is considered objective, the process of setting rest intervals to calculate sleep variables is subjective. We sought to evaluate the reproducibility of actigraphy-derived measures of sleep using a standardized algorithm for setting rest intervals.
  
  
  METHODS
  Observational study.
  
  
  METHODS
  Community-based.
  
  
  METHODS
  A random sample of 50 adults aged 18-64 years free of severe sleep apnea participating in the Sueño sleep ancillary study to the Hispanic Community Health Study/Study of Latinos.
  
  
  METHODS
  N/A.
  
  
  RESULTS
  Participants underwent 7 days of continuous wrist actigraphy and completed daily sleep diaries. Studies were scored twice by each of two scorers. Rest intervals were set using a standardized hierarchical approach based on event marker, diary, light, and activity data. Sleep/wake status was then determined for each 30-sec epoch using a validated algorithm, and this was used to generate 11 variables: mean nightly sleep duration, nap duration, 24-h sleep duration, sleep latency, sleep maintenance efficiency, sleep fragmentation index, sleep onset time, sleep offset time, sleep midpoint time, standard deviation of sleep duration, and standard deviation of sleep midpoint. Intra-scorer intraclass correlation coefficients (ICCs) were high, ranging from 0.911 to 0.995 across all 11 variables. Similarly, inter-scorer ICCs were high, also ranging from 0.911 to 0.995, and mean inter-scorer differences were small. Bland-Altman plots did not reveal any systematic disagreement in scoring.
  
  
  CONCLUSIONS
  With use of a standardized algorithm to set rest intervals, scoring of actigraphy for the purpose of generating a wide array of sleep variables is highly reproducible.
authors.affiliation: Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.|Beth Israel Deaconess Medical Center, Boston, MA.
authors.forename: Sanjay R
authors.initials: SR
authors.lastname: Patel
authors.affiliation: Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
authors.forename: Jia
authors.initials: J
authors.lastname: Weng
authors.affiliation: Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
authors.forename: Michael
authors.initials: M
authors.lastname: Rueschman
authors.affiliation: Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
authors.forename: Katherine A
authors.initials: KA
authors.lastname: Dudley
authors.affiliation: University of California San Diego, San Diego, CA.
authors.forename: Jose S
authors.initials: JS
authors.lastname: Loredo
authors.affiliation: Albert Einstein College of Medicine, Bronx, NY.
authors.forename: Yasmin
authors.initials: Y
authors.lastname: Mossavar-Rahmani
authors.affiliation: Beth Israel Deaconess Medical Center, Boston, MA.
authors.forename: Maricelle
authors.initials: M
authors.lastname: Ramirez
authors.affiliation: University of Miami, Miami, FL.
authors.forename: Alberto R
authors.initials: AR
authors.lastname: Ramos
authors.affiliation: Northwestern University, Chicago, IL.
authors.forename: Kathryn
authors.initials: K
authors.lastname: Reid
authors.affiliation: Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
authors.forename: Ashley N
authors.initials: AN
authors.lastname: Seiger
authors.affiliation: Collaborative Studies Coordinating Center, Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC.
authors.forename: Daniela
authors.initials: D
authors.lastname: Sotres-Alvarez
authors.affiliation: Northwestern University, Chicago, IL.
authors.forename: Phyllis C
authors.initials: PC
authors.lastname: Zee
authors.affiliation: Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
mesh_terms: D056044:Actigraphy / Q000379:methods* / Q000592:standards*; D000293:Adolescent; D000328:Adult; D000465:Algorithms; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D057566:Self Report; D012890:Sleep / Q000502:physiology*; D012892:Sleep Deprivation; D013997:Time Factors; D014953:Wrist; D055815:Young Adult
keywords: Hispanic; actigraphy; reproducibility; sleep
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