title: Antiviral treatment of influenza in South Korea.
abstract: Antiviral therapy has an important role in the treatment and chemoprophylaxis of influenza. At present, two classes of antiviral agents, adamantanes and neuraminidase inhibitors, are available for the treatment and chemoprophylaxis of influenza in Korea. Because of the widespread resistance against adamantanes, neuraminidase inhibitors are mainly used. Because each country has a unique epidemiology of influenza, the proper use of antiviral agents should be determined based on local data. Decisions on the clinical practice in the treatment of influenza in South Korea are guided by the local surveillance data, practice guidelines, health insurance system and the resistance patterns of the circulating influenza viruses. This review highlights the role of antiviral agents in the treatment and outcome of influenza in Korea by providing comprehensive information of their clinical usage in Korea.
authors.affiliation: Department of Pediatrics, Seoul National University Hospital, Seoul, Korea.
authors.forename: Young June
authors.initials: YJ
authors.lastname: Choe
authors.forename: Hyunju
authors.initials: H
authors.lastname: Lee
authors.forename: Hoan Jong
authors.initials: HJ
authors.lastname: Lee
authors.forename: Eun Hwa
authors.initials: EH
authors.lastname: Choi
mesh_terms: D000998:Antiviral Agents / Q000009:adverse effects / Q000627:therapeutic use*; D018890:Chemoprevention; D024882:Drug Resistance, Viral; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D007251:Influenza, Human / Q000188:drug therapy* / Q000453:epidemiology*; D009439:Neuraminidase / Q000378:metabolism; D009975:Orthomyxoviridae / Q000187:drug effects*; D017410:Practice Guidelines as Topic; D062486:Public Health Surveillance; D056910:Republic of Korea
chemical_list: D000998:Antiviral Agents; D004791:Enzyme Inhibitors; D009439:Neuraminidase
keywords: Korea; chemoprophylaxis; influenza; neuraminidase inhibitor; treatment