title: The Trend of Inflammatory Bowel Diseases in Taiwan: A Population-Based Study.
abstract: OBJECTIVE
  The purpose of this study was to estimate the sex- and age-specific incidence rates of inflammatory bowel diseases (IBD) in Taiwan. Site-specific cancer occurred in patients with IBD would be reported, too.
  
  
  METHODS
  A retrospective study by analyzing the data from the National Health Insurance Research Database of Taiwan.
  
  
  RESULTS
  Between 2000 and 2010, the overall incidence rate of Crohn's disease (CD) and ulcerative colitis (UC) was 0.208 and 0.838 per 100,000 person-years. For male, the incidence rate of CD was 0.195 (95 % CI 0.113-0.276) per 100,000 persons in 2000 and increased to 0.318 (95 % CI 0.216-0.421) per 100,000 persons in 2010. For female, the incidence rate of CD was 0.092 (95 % CI 0.035-0.149) per 100,000 persons in 2000 and increased to 0.210 (95 % CI 0.128-0.293) per 100,000 persons in 2010. For male, the incidence rate of UC was 0.690 (95 % CI 0.537-0.843) per 100,000 persons in 2000 and increased to 1.351 (95 % CI, 1.140-1.562) per 100,000 persons in 2010. For female, the incidence rate of UC was 0.386 (95 % CI 0.269-0.503) per 100,000 persons in 2000 and increased to 0.858 (95 % CI 0.691-1.024) per 100,000 persons in 2010. Among the CD patients, 0.19 % had colorectal cancers (1/519). Among the UC patients, 0.24 % had colorectal cancers (5/2098).
  
  
  CONCLUSIONS
  This nationwide population-based longitudinal epidemiological study of IBD in Taiwan provides data for future global comparisons.
authors.affiliation: Department of Gastroenterology and Hepatology, College of Medicine, Chang Gung Memorial Hospital, Chang Gung University, 5, Fushin Street, Kweishan, Taoyuan, Taiwan, ROC.
authors.forename: Chia-Jung
authors.initials: CJ
authors.lastname: Kuo
authors.forename: Kuang-Hui
authors.initials: KH
authors.lastname: Yu
authors.forename: Lai-Chu
authors.initials: LC
authors.lastname: See
authors.forename: Cheng-Tang
authors.initials: CT
authors.lastname: Chiu
authors.forename: Ming-Yao
authors.initials: MY
authors.lastname: Su
authors.forename: Chen-Ming
authors.initials: CM
authors.lastname: Hsu
authors.forename: Chang-Fu
authors.initials: CF
authors.lastname: Kuo
authors.forename: Meng-Jiun
authors.initials: MJ
authors.lastname: Chiou
authors.forename: Jia-Rou
authors.initials: JR
authors.lastname: Liu
authors.forename: Hung-Wei
authors.initials: HW
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D015212:Inflammatory Bowel Diseases / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult
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