title: [A case of bisalbuminemia in a patient with digestive adenocarcinoma].
abstract: Bisalbuminemia whether hereditary or acquired, is a rare electrophoretic abnormality of albumin, characterized by a duplication of the albumin fraction on the electrophoretic trace of the serum proteins. This duplication reflects the presence in the same individual normal plasma albumin and a modified albumin.
  
  
  METHODS
  This is a patient of 62 years hospitalized at the Internal Medicine Department of HMIMV for liver metastases of gastrointestinal adenocarcinoma and including serum protein electrophoresis (EP) performed on capillary (Capillarys society Sebia) reveals bisalbuminemia. The family investigation has ruled that inheritance of acquired bisalbuminemia to retain appearance.
  
  
  CONCLUSIONS
  Bisalbuminemia acquired outside treatment with high doses of beta-lactam antibiotics, chronic pancreatitis with pseudocyst rupture or fixing a monoclonal immunoglobulin on albumin in the myeloma subjects is an exceptional event. The pathophysiologic mechanism in the reported cases remains unexplained as is also the case of acquired bisalbuminemias associated with other pathological contexts (Alzheimer's disease nephrotic syndrome).
  
  
  CONCLUSIONS
  To the best of our knowledge, the bisalbuminemia in the gastrointestinal adenocarcinoma liver metastases has not been reported to date, hence the importance of the reported cases.
authors.affiliation: Service de biochimie, Hôpital militaire d'instruction Mohamed V (HMIMV), Rabat, Maroc, Université Mohamed V Souissi, Faculté de médicine et de pharmacie Rabat, Maroc.
authors.forename: Fatima Zahra
authors.initials: FZ
authors.lastname: Hajoui
authors.affiliation: Service de biochimie, Hôpital militaire d'instruction Mohamed V (HMIMV), Rabat, Maroc, Université Mohamed V Souissi, Faculté de médicine et de pharmacie Rabat, Maroc.
authors.forename: Asmaa
authors.initials: A
authors.lastname: Biaz
authors.affiliation: Service de biochimie, Hôpital militaire d'instruction Mohamed V (HMIMV), Rabat, Maroc, Université Mohamed V Souissi, Faculté de médicine et de pharmacie Rabat, Maroc.
authors.forename: Lamyaa
authors.initials: L
authors.lastname: Zouiten
authors.affiliation: Service de biochimie, Hôpital militaire d'instruction Mohamed V (HMIMV), Rabat, Maroc, Université Mohamed V Souissi, Faculté de médicine et de pharmacie Rabat, Maroc.
authors.forename: Samira
authors.initials: S
authors.lastname: Mechtani
authors.affiliation: Service de biochimie, Hôpital militaire d'instruction Mohamed V (HMIMV), Rabat, Maroc, Université Mohamed V Souissi, Faculté de médicine et de pharmacie Rabat, Maroc.
authors.forename: Abdellah
authors.initials: A
authors.lastname: Dami
authors.affiliation: Service de biochimie, Hôpital militaire d'instruction Mohamed V (HMIMV), Rabat, Maroc, Université Mohamed V Souissi, Faculté de médicine et de pharmacie Rabat, Maroc.
authors.forename: Sanaa
authors.initials: S
authors.lastname: Bouhsain
authors.affiliation: Service de biochimie, Hôpital militaire d'instruction Mohamed V (HMIMV), Rabat, Maroc, Université Mohamed V Souissi, Faculté de médicine et de pharmacie Rabat, Maroc.
authors.forename: Zohra
authors.initials: Z
authors.lastname: Ouzzif
mesh_terms: D000230:Adenocarcinoma / Q000097:blood* / Q000473:pathology*; D000418:Albumins / Q000378:metabolism*; D001797:Blood Protein Electrophoresis; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000097:blood* / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000556:secondary*; D008875:Middle Aged
chemical_list: D000418:Albumins; C030764:bisalbumins
keywords: adenocarcinoma; bisalbuminemia; liver metastases