title: Effects of genetic variants in the promoter region of the bovine adiponectin (ADIPOQ) gene on marbling of Hanwoo beef cattle.
abstract: This study aimed to verify genetic effects of the bovine adiponectin (ADIPOQ) gene on carcass traits of Hanwoo cattle. The measured carcass traits were marbling score (MAR), backfat thickness (BFT), loineye area (LEA), and carcass weight (CAW). Selection of primers was based on the bovine ADIPOQ sequence, and the analysis amplified approximately 267 and 333 bp genomic segments, including 67 bp of insertions in the promoter region. Sequencing analysis confirmed genetic variants (g.81966235C>T, g.81966377T>C, and g.81966364D>I) that showed significant effects on MAR. The present results suggest that the identified SNPs are useful genetic markers for the improvement of carcass traits in Hanwoo cattle.
authors.affiliation: Animal Genomics Bioinformatics Division, National Institute of Animal Science, Suwon, 441-701, Republic of Korea.
authors.forename: Yoonjeong
authors.initials: Y
authors.lastname: Choi
authors.affiliation: The Ohio State University, Department of Animal Science, Columbus OH 43210, USA.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Davis
authors.affiliation: Animal Genomics Bioinformatics Division, National Institute of Animal Science, Suwon, 441-701, Republic of Korea. Electronic address: chung133@korea.kr.
authors.forename: Hoyoung
authors.initials: H
authors.lastname: Chung
mesh_terms: D000003:Abattoirs; D052242:Adiponectin / Q000235:genetics* / Q000378:metabolism; D050154:Adiposity; D000483:Alleles; D000818:Animals; D017849:Animals, Inbred Strains; D001835:Body Weight; D002417:Cattle; D063427:Food Quality; D005787:Gene Frequency; D056726:Genetic Association Studies / Q000662:veterinary; D014644:Genetic Variation; D008460:Meat / Q000032:analysis*; D018482:Muscle, Skeletal / Q000254:growth & development / Q000378:metabolism*; D020641:Polymorphism, Single Nucleotide; D011401:Promoter Regions, Genetic; D056910:Republic of Korea
chemical_list: D052242:Adiponectin
keywords: ADIPOQ; Carcass trait; Hanwoo cattle; Polymorphism