title: Hypercalcemic crisis due to primary hyperparathyroidism occurring concomitantly with Graves' disease.
abstract: We herein describe a case of hypercalcemic crisis in a 52-year-old Japanese woman. She suffered from thirst and fatigue for one month. Her serum calcium (a) levels were 19.0 mg/dL, and she was diagnosed with hypercalcemic crisis. Circulating levels of parathyroid and thyroid hormones were elevated. She was diagnosed with primary hyperparathyroidism accompanied by Graves' disease. Thyroparathyroidectomy was performed after circulating levels of Ca and thyroid hormones were normalized. Both of primary hyperparathyroidism and Graves' disease can contribute and accelerate hypercalcemia, resulting in a state of crisis. The possibility of their coexistence should therefore be taken into consideration in cases of hypercalcemia.
authors.affiliation: Department of Medicine, Diabetes, Metabolism and Endocrinology, Matsuyama Red Cross Hospital, Japan.
authors.forename: Maki
authors.initials: M
authors.lastname: Yokomoto
authors.forename: Mayu
authors.initials: M
authors.lastname: Minamoto
authors.forename: Daisuke
authors.initials: D
authors.lastname: Utsunomiya
authors.forename: Hironobu
authors.initials: H
authors.lastname: Umakoshi
authors.forename: Tomikazu
authors.initials: T
authors.lastname: Fukuoka
authors.forename: Shiori
authors.initials: S
authors.lastname: Kondo
mesh_terms: D005260:Female; D006111:Graves Disease / Q000150:complications*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D049950:Hyperparathyroidism, Primary / Q000150:complications*; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000378:metabolism; D013963:Thyroid Hormones / Q000378:metabolism
chemical_list: D010281:Parathyroid Hormone; D013963:Thyroid Hormones