title: Become Related: FIAS, an Intensive Early Intervention for Young Children with Autism Spectrum Disorders.
abstract: BACKGROUND
  In autism spectrum disorders (ASDs), impairments in fundamental social abilities and a lack of interest in social stimuli become apparent early in life. These impairments are thought to negatively affect further brain and behavioural development. Early intensive interventions can help to attenuate social-development and other risk factors and, thus, to ameliorate the deficits associated with ASDs. We present FIAS, an intensive early intervention approach for young children with ASD, which aims at developing children's social motivation. During 18 days, therapists work continuously for 6 h a day with the affected child, involving the whole family in a day care setting. Follow-up care at home over 1 year as well as fresh-up interventions and inclusion in kindergarten or a play group should stabilise the effects and help to respond to further challenges.
  
  
  METHODS
  Here, we present observations from the first 12 patients (25-48 months of age) treated according to the FIAS approach. We evaluated changes in core autistic symptoms and level of functioning after the 18 days of intensive intervention. Beyond standardised assessment, two innovative video-based instruments (Autism Behaviour Coding System and Evaluationsfragebogen) have been developed to assess autistic symptoms and interaction parameters during intervention.
  
  
  RESULTS
  Improvements were noted in most core autistic symptom domains, with the highest effect sizes in domains like eye contact, communication, repetitive behaviour, imitation, motivation and reciprocity. In addition, the level of functioning significantly improved.
  
  
  CONCLUSIONS
  The first evaluation of the FIAS approach shows promising results, as the FIAS intervention appears to improve core autistic symptom domains as well as the level of everyday functioning. Limitations of this study are the small sample size and the lack of a control group. A more comprehensive and longitudinal evaluation is in progress; this will focus on the stability of the observed effects and will attempt to identify potential predictors of treatment response. © 2015 S. Karger AG, Basel.
authors.affiliation: University Department of Child and Adolescent Psychiatry, Basel, Switzerland.
authors.forename: Evelyn
authors.initials: E
authors.lastname: Herbrecht
authors.forename: Esther
authors.initials: E
authors.lastname: Kievit
authors.forename: René
authors.initials: R
authors.lastname: Spiegel
authors.forename: Diana
authors.initials: D
authors.lastname: Dima
authors.forename: Kirstin
authors.initials: K
authors.lastname: Goth
authors.forename: Klaus
authors.initials: K
authors.lastname: Schmeck
mesh_terms: D001321:Autistic Disorder / Q000523:psychology / Q000628:therapy; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis / Q000523:psychology* / Q000628:therapy*; D002675:Child, Preschool; D003142:Communication; D018479:Early Intervention, Educational / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009042:Motivation; D018401:Sample Size; D012919:Social Behavior; D016896:Treatment Outcome