title: Lipofuscin, lipofuscin-like pigments and autofluorescence.
abstract: A brief overview is here provided on lipofuscin and lipofuscin-like substances, with particular reference to their biological significance as well as to their cellular origin and pathophysiological role. Special emphasis is also placed on the mutual relationships between lipofuscin and lipofuscin-like lipopigments on one side, and cell autofluorescence on the other.
authors.affiliation: University of Teramo. gdiguardo@unite.it.
authors.forename: G
authors.initials: G
authors.lastname: Di Guardo
mesh_terms: D000818:Animals; D001343:Autophagy; D002477:Cells / Q000737:chemistry / Q000378:metabolism*; D005453:Fluorescence; D006801:Humans; D008055:Lipids / Q000737:chemistry*; D008062:Lipofuscin / Q000737:chemistry* / Q000378:metabolism
chemical_list: D008055:Lipids; D008062:Lipofuscin; C051596:lipopigments
references.citation: Pathol Int. 2005 May;55(5):280-4
references.pmid: 15871726
references.citation: Adv Exp Med Biol. 2014;801:105-11
references.pmid: 24664687
references.citation: Nat Rev Mol Cell Biol. 2014 Mar;15(3):153
references.pmid: 24496390
references.citation: Dermatol Pract Concept. 2014 Apr 30;4(2):45-9
references.pmid: 24855574
references.citation: Exp Toxicol Pathol. 2012 Jan;64(1-2):51-6
references.pmid: 20598870
references.citation: J Exp Clin Cancer Res. 2011;30:45
references.pmid: 21521500
references.citation: Pol J Pathol. 2013 Oct;64(3):228-31
references.pmid: 24166611
references.citation: Free Radic Biol Med. 2012 Nov 1;53(9):1760-9
references.pmid: 22982048
references.citation: Arch Gerontol Geriatr. 2002 May-Jun;34(3):343-57
references.pmid: 14764335
references.citation: Biosci Rep. 1982 Aug;2(8):561-7
references.pmid: 7139071
references.citation: Lasers Surg Med. 2006 Jul;38(6):598-607
references.pmid: 16770771
references.citation: Nat Methods. 2014 Nov;11(11):1161-9
references.pmid: 25262208
references.citation: PLoS One. 2010;5(4):e10075
references.pmid: 20419124
references.citation: Redox Biol. 2013;1:140-4
references.pmid: 24024146
references.citation: Pathobiol Annu. 1980;10:253-67
references.pmid: 7003495
references.citation: Eur J Histochem. 2014;58(4):2461
references.pmid: 25578980
references.citation: Toxicol Lett. 2000 Mar 15;112-113:9-16
references.pmid: 10720707
references.citation: Lasers Surg Med. 2013 Nov;45(9):597-607
references.pmid: 24114723
references.citation: Free Radic Biol Med. 2010 Apr 15;48(8):1100-8
references.pmid: 20116426
references.citation: Antioxid Redox Signal. 2014 Jul 1;21(1):123-37
references.pmid: 24512092
references.citation: PLoS One. 2011;6(5):e19417
references.pmid: 21673789
references.citation: Mech Ageing Dev. 1992 Jul 15;64(3):293-302
references.pmid: 1405786