title: Enhancers: holding out for the right promoter.
abstract: Some transcriptional enhancers work best with one type of promoter, while ignoring others. How widespread is such specificity across the genome? A new study finds that, in a fair fight, most enhancers prefer to activate promoters resembling those of their parent genes.
authors.affiliation: Department of Cell and Developmental Biology and Program in Cellular and Molecular Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
authors.forename: David S
authors.initials: DS
authors.lastname: Lorberbaum
authors.affiliation: Department of Cell and Developmental Biology and Program in Cellular and Molecular Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address: sbarolo@umich.edu.
authors.forename: Scott
authors.initials: S
authors.lastname: Barolo
mesh_terms: D000818:Animals; D004331:Drosophila melanogaster / Q000196:embryology* / Q000235:genetics*; D004742:Enhancer Elements, Genetic / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental / Q000235:genetics*; D020043:Genes, Essential / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics*
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