title: Anaphylaxis to insect stings.
abstract: Anaphylaxis to insect stings has occurred in 3% of adults and can be fatal even on the first reaction. Large local reactions are more frequent but rarely dangerous. The chance of a systemic reaction to a sting is 5% to 10% in large local reactors and in children with mild (cutaneous) systemic reactions, and varies between 30% and 65% in adults with previous systemic reactions, depending on the severity of previous sting reactions. Baseline serum tryptase level is increased in many patients with sting anaphylaxis. Venom immunotherapy is 75% to 98% effective in preventing sting anaphylaxis.
authors.affiliation: Division of Allergy-Immunology, Johns Hopkins University, 7939 Honeygo Boulevard #219, Baltimore, MD 21236, USA. Electronic address: dgolden1@jhmi.edu.
authors.forename: David B K
authors.initials: DB
authors.lastname: Golden
mesh_terms: D000707:Anaphylaxis / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control / Q000628:therapy; D000818:Animals; D003937:Diagnosis, Differential; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007299:Insect Bites and Stings / Q000276:immunology*; D012307:Risk Factors
chemical_list: D007073:Immunoglobulin E
keywords: Anaphylaxis; Diagnostic tests; Hymenoptera; Immunotherapy; Insect sting; Mastocytosis; Venom