title: Microdosimetry of the Auger electron emitting 123I radionuclide using Geant4-DNA simulations.
abstract: Microdosimetric calculations of the Auger electron emitter (123)I were done in liquid water spheres using the Geant4 toolkit. The electron emission spectrum of (123)I produced by Geant4 is presented. Energy deposition and corresponding S-values were calculated to investigate the influence of the sub-cellular localization of the Auger emitter. It was found that S-values calculated by the Geant4 toolkit are generally lower than the values calculated by other Monte Carlo codes for the (123)I radionuclide. The differences in the compared S-values are mainly due to the different particle emission spectra employed by the respective computational codes and emphasizes the influence of the spectra on dosimetry calculations.
authors.affiliation: Department of Physics, Stellenbosch University, P. Bag X1, Matieland, Stellenbosch 7602, South Africa.
authors.forename: H
authors.initials: H
authors.lastname: Fourie
authors.forename: R T
authors.initials: RT
authors.lastname: Newman
authors.forename: J P
authors.initials: JP
authors.lastname: Slabbert
mesh_terms: D003198:Computer Simulation; D004247:DNA / Q000737:chemistry*; D004579:Electron Transport; D004583:Electrons; D006801:Humans; D007457:Iodine Radioisotopes / Q000737:chemistry*; D009010:Monte Carlo Method; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy; D011874:Radiometry / Q000379:methods*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D014867:Water; D004247:DNA