title: Epidemiological and statistical considerations for interpreting and communicating oncology clinical trials.
abstract: The use of randomised controlled trials (RCTs) in veterinary oncological research and practice is increasing as is the number of relevant scientific publications. While clear guidelines exist for the reporting of RCTs, a thorough understanding of statistical and epidemiological concepts is required in order to accurately interpret and then impart the results of such trials, and to make balanced decisions regarding the uptake of published findings. This review presents the most important epidemiological and statistical considerations that are needed in order to interpret and communicate with confidence the results of oncology clinical trials.
authors.affiliation: School of Animal and Veterinary Sciences, Charles Sturt University, Wagga Wagga 2650 Australia. Electronic address: jheller@csu.edu.au.
authors.forename: Jane
authors.initials: J
authors.lastname: Heller
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001699:Biometry; D009369:Neoplasms / Q000628:therapy / Q000662:veterinary*; D016032:Randomized Controlled Trials as Topic / Q000379:methods / Q000706:statistics & numerical data; D012107:Research Design
chemical_list: D000970:Antineoplastic Agents
keywords: Epidemiology; Oncology; Randomised controlled trial; Risk; Statistics; Veterinary