title: [Antimicrobial activity of Actinomycetale isolated from the lagoon in Algeria].
abstract: In the aim of the study of the taxonomy and the antimicrobial activity, a strain of actinomycete SM2/2GF which was isolated from sediment of the lagoon El-Mellah which is situated in the city of El-Kala in the Northeast of Algeria, was tested against diverse pathogenic microorganisms and against a Gram-negative bacterium Pseudomonas alcaliphila which was isolated from water of the lagoon El-Mellah. The phenotypic and the molecular characteristics show that the isolate SM2/2GF belongs to the kind Streptomyces. This strain showed an antimicrobial activity against a Gram-negative bacterium Pseudomonas alcaliphila and the positive-Gram bacteria as Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtilis, Enterococcus faecalis, as well as the yeast Candida albicans. It has no activity against Pseudomonas aeruginosa. The interesting antimicrobial activity of the strain SM2/2GF against the pathogenic microorganisms could encourage further researches on one or several bioactive molecules which it secretes.
authors.affiliation: Département de biochimie, Faculté des Sciences, Université Badji Mokhtar, Annaba, Algérie.
authors.forename: Chérifa
authors.initials: C
authors.lastname: Alliouch-Kerboua
authors.affiliation: Département de biochimie, Faculté des Sciences, Université Badji Mokhtar, Annaba, Algérie, Laboratoire d'amélioration génétique des plantes, Département de biologie, Faculté des sciences, Université Badji Mokhtar, Annaba, Algérie.
authors.forename: Djamila
authors.initials: D
authors.lastname: Gacemi Kirane
authors.affiliation: Unité de recherche sur les maladies infectieuses et tropicales émergentes (Urmite), UM63, CNRS 7278, IRD 198, Inserm 1095, Faculté de médecine, Aix Marseille Université, Marseille, France.
authors.forename: Bernard
authors.initials: B
authors.lastname: La Scola
mesh_terms: D000192:Actinomycetales / Q000302:isolation & purification* / Q000502:physiology*; D000462:Algeria; D000890:Anti-Infective Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects / Q000254:growth & development; D002176:Candida albicans / Q000187:drug effects / Q000254:growth & development; D019015:Geologic Sediments / Q000382:microbiology; D006801:Humans; D060106:Lakes / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000254:growth & development; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development; D014871:Water Microbiology; D060753:Water Quality / Q000592:standards
chemical_list: D000890:Anti-Infective Agents
keywords: Streptomyces; antimicrobial activity; sediment