title: [Preterm rupture of membranes: Is home care a safe management?].
abstract: OBJECTIVE
  Compare the maternal and neonatal outcomes in pregnancies complicated by preterm prelabour rupture of membranes (PPROM), which were managed either at home (HAD) or hospital (HC).
  
  
  METHODS
  Retrospective study in two level III maternities during 2 years. Inclusion criteria in HAD were: singleton pregnancy, PPROM between 24 and 35 weeks of gestation, absence of chorioamnionitis, clinical stability at D7 of the rupture, cervical dilatation <3 cm, patient residing in the geographic area.
  
  
  RESULTS
  Thirty-two patients were included in the HAD group and 24 in the HC group. Our populations were similar in the 2 groups. The duration of latency was longer in the HAD group than in the HC group (27.5 d [20-37] versus 16.5 d [12.5 to 29.5]; P=0.026). Patients in the HAD group received fewer antibiotics with a similar rate of chorioamnionitis. No difference in terms of obstetrical and neonatal outcomes was observed. Number of days in neonatal resuscitation was lower in the HAD group than in the HC group (12.5 d [10-22] versus 43 d [20-52]; P=0.003).
  
  
  CONCLUSIONS
  HAD seems to be an alternative to continuous hospitalization for patients followed for PPROM between 24 and 35 weeks. A randomized study with a larger number of patients, including other data such as maternal satisfaction and cost analysis, would be interesting to confirm those preliminary results.
authors.affiliation: Pôle d'obstétrique, pôle Femme-Mère-Nouveau-né, maternité Jeanne-de-Flandre, clinique d'obstétrique, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France. Electronic address: charles.garabedian@chru-lille.fr.
authors.forename: C
authors.initials: C
authors.lastname: Garabedian
authors.affiliation: Pôle d'obstétrique, pôle Femme-Mère-Nouveau-né, maternité Jeanne-de-Flandre, clinique d'obstétrique, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Bocquet
authors.affiliation: EA2694, département de biostatistiques, UDSL, université de Lille, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Duhamel
authors.affiliation: Hospitalisation à domicile, CHRU de Lille, 59037 Lille, France.
authors.forename: B
authors.initials: B
authors.lastname: Rousselle
authors.affiliation: Hospitalisation à domicile, CHRU de Lille, 59037 Lille, France.
authors.forename: S
authors.initials: S
authors.lastname: Balagny
authors.affiliation: Pôle d'obstétrique, pôle Femme-Mère-Nouveau-né, maternité Jeanne-de-Flandre, clinique d'obstétrique, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France.
authors.forename: E
authors.initials: E
authors.lastname: Clouqueur
authors.affiliation: Pôle Femme-Mère-Nouveau-né, centre hospitalier de Valenciennes, 59322 Valenciennes, France.
authors.forename: N
authors.initials: N
authors.lastname: Tillouche
authors.affiliation: Pôle d'obstétrique, pôle Femme-Mère-Nouveau-né, maternité Jeanne-de-Flandre, clinique d'obstétrique, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France; Faculté de médecine Henri-Warembourg, université de Lille, 59045 Lille cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Deruelle
mesh_terms: D000328:Adult; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000453:epidemiology / Q000628:therapy*; D005865:Gestational Age; D006699:Home Care Services / Q000592:standards / Q000706:statistics & numerical data; D006760:Hospitalization / Q000706:statistics & numerical data; D006771:Hospitals, Maternity / Q000706:statistics & numerical data; D006801:Humans; D007231:Infant, Newborn; D007744:Obstetric Labor Complications / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D012189:Retrospective Studies; D055815:Young Adult
keywords: Complications néonatales; Home care; Hospital care; Hospitalisation conventionnelle; Hospitalisation à domicile; Neonatal; Outcome; Preterm premature rupture of membranes; Rupture prématurée des membranes