title: The impact of laparoscopic Nissen fundoplication on the long-term quality of life in patients with gastroesophageal reflux disease.
abstract: Laparoscopic Nissen fundoplication is now the most common surgical procedure for treatment of gastroesophageal reflux disease (GERD), offering promising long-term outcomes. Outcomes for 46 patients with GERD who underwent Nissen fundoplication during the last 5 years (November 2007-June 2012) were prospectively studied using a structured questionnaire that evaluated clinical symptom scores for heartburn, dysphagia, and satisfaction with clinical outcomes. Postoperative care of the patients including analgesia, median hospital stay, overall cost, and complications was also studied. Clinical follow-up data for 2 years after surgery were available for all 46 patients. Forty-two patients (91.3%) were satisfied with their quality of life and only eight patients (17.4%) continued to receive antacids after surgery. Dysphagia to solid and liquid occasionally appeared in 26.1% (N = 12) and 17.4% (N = 8) of patients, respectively. Laparoscopic Nissen fundoplication was an effective long-term treatment for GERD. The operation resulted in a significant reduction of symptoms and minimized the use of antacid drugs with a high degree of patient satisfaction. Although some patients may have returned to antacid treatment at late follow-up or continued to complain of mild discomfort, they were overall pleased with the outcome.
authors.affiliation: Dimitrios P. Korkolis, PhD, MD, is Consultant Surgeon, Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece. Maria Kapritsou, MSc, BSN, RN, is Nurse, Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece, and National and Kapodistrian University of Athens, Athens, Greece. Evangelos A. Konstantinou, PhD, RN, is Assistant Professor of Nursing Anesthesiology, National and Kapodistrian University of Athens, Athens, Greece. Margaret Giannakopoulou, PhD, RN, is Assistant Professor, National and Kapodistrian University of Athens, Athens, Greece. Maria S. Chrysi, MSc, RN, is Nurse, Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece. Maria Tsakiridou, RN, is Head Chief Nurse of Surgical Clinic, Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece. Andriana Kouloura, MD, is Resident in Surgery, Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece. Matthaios Flamourakis, MD, is Resident in Surgery, Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece. Mariantonietta Maricosu, MD, is Resident in Surgery, Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece. Emmanuil Gontikakis, PhD, MD, is Director of Surgical Clinic, Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece. George Plataniotis, MD, is Director of Surgical Clinic, Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece.
authors.forename: Dimitrios P
authors.initials: DP
authors.lastname: Korkolis
authors.forename: Maria
authors.initials: M
authors.lastname: Kapritsou
authors.forename: Evangelos A
authors.initials: EA
authors.lastname: Konstantinou
authors.forename: Margaret
authors.initials: M
authors.lastname: Giannakopoulou
authors.forename: Maria S
authors.initials: MS
authors.lastname: Chrysi
authors.forename: Maria
authors.initials: M
authors.lastname: Tsakiridou
authors.forename: Andriana
authors.initials: A
authors.lastname: Kouloura
authors.forename: Matthaios
authors.initials: M
authors.lastname: Flamourakis
authors.forename: Mariantonietta
authors.initials: M
authors.lastname: Maricosu
authors.forename: Emmanuil
authors.initials: E
authors.lastname: Gontikakis
authors.forename: George
authors.initials: G
authors.lastname: Plataniotis
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011788:Quality of Life; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult