title: [Guided clinical practice guidelines: how to blunt the weapon of evidence].
abstract: The public should trust practice guidelines only if the recommendations accurately reflect the underlying evidence about benefits and harms to individual patients. However, the process of development of clinical practice guidelines is fraught with problem, conflicts and controversies. A few examples, starting from the guidelines on osteoporosis are presented and commented on.
authors.forename: Emilio
authors.initials: E
authors.lastname: Maestri
authors.forename: Giulio
authors.initials: G
authors.lastname: Formoso
mesh_terms: D016265:Conflict of Interest; D003929:Diabetic Neuropathies / Q000451:nursing*; D019317:Evidence-Based Medicine; D019983:Guideline Adherence; D017408:Guidelines as Topic; D006801:Humans; D007558:Italy; D010024:Osteoporosis / Q000451:nursing*; D017410:Practice Guidelines as Topic / Q000592:standards; D011787:Quality of Health Care; D016032:Randomized Controlled Trials as Topic; D012196:Review Literature as Topic; D012307:Risk Factors