title: Targeting Autophagy in BRAF-Mutant Tumors.
abstract: Recent studies have highlighted the opportunity to treat cancer by inhibiting autophagy, but have also raised important caveats with this idea. An article in this issue of Cancer Discovery adds to accumulating evidence suggesting that we should focus our efforts (at least initially) on specific tumors where we are most likely to see beneficial effects.
authors.affiliation: Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado. Andrew.Thorburn@ucdenver.edu.
authors.forename: Andrew
authors.initials: A
authors.lastname: Thorburn
authors.affiliation: Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Morgan
mesh_terms: D000818:Animals; D008545:Melanoma / Q000235:genetics*; D008869:Microtubule-Associated Proteins / Q000235:genetics*; D009154:Mutation; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics*
chemical_list: D008869:Microtubule-Associated Proteins; D048493:Proto-Oncogene Proteins B-raf
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