title: Analysis of Hyoid-Larynx Complex Using 3D Geometric Morphometrics.
abstract: The aim of this study was to obtain a quantitative anatomical description of the hyoid bone-larynx complex using modern 3D reconstruction tools. The study was conducted on 104 bones from CT scan images of living adult subjects. Three-dimensional reconstructions were created from CT scan images using AVIZO 6.2 software package. A study of this complex was carried out using metric and morphological analyses. Characteristics of the hyoid bone and larynx were highly heterogeneous and were closely linked with the sex, height, and weight of the individuals. Height and width of larynx were significantly greater in men than in women (24.99 vs. 17.3 mm, p ≤ 0.05 and 46.75 vs. 41.07, p ≤ 0.05), whereas the thyroid angle was larger in females (81.12° vs. 74.48°, p ≤ 0.05). There was a significant correlation between the height and weight of subjects and different measurements of the hyoid-larynx complex. (Pearson's coefficient correlation r = 0.42, p ≤ 0.05 between the height of thyroid ala and the height of subjects and r = 0.1, p ≤ 0.05 between the height of thyroid ala and the weight of subjects). Shape and size analysis of the hyoid-larynx complex showed the existence of a significant sexual dimorphism and high interindividual heterogeneity depending to patient morphology. These results encourage us to go further with functional and imaging correlations.
authors.affiliation: Service d'ORL et Chirurgie Cervico-Faciale, Assistance Publique-Hôpitaux de Marseille (AP-HM), Aix-Marseille Université, Centre Hospitalier Universitaire (CHU) La Timone, 264, rue Saint Pierre, 13385, Marseille Cedex 05, France.
authors.forename: Anthony
authors.initials: A
authors.lastname: Loth
authors.forename: Julien
authors.initials: J
authors.lastname: Corny
authors.forename: Laure
authors.initials: L
authors.lastname: Santini
authors.forename: Laurie
authors.initials: L
authors.lastname: Dahan
authors.forename: Patrick
authors.initials: P
authors.lastname: Dessi
authors.forename: Pascal
authors.initials: P
authors.lastname: Adalian
authors.forename: Nicolas
authors.initials: N
authors.lastname: Fakhry
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D006928:Hyoid Bone / Q000033:anatomy & histology*; D021621:Imaging, Three-Dimensional; D007830:Larynx / Q000033:anatomy & histology*; D008297:Male; D008875:Middle Aged
references.citation: Anat Rec (Hoboken). 2007 Mar;290(3):268-76
references.pmid: 17525943
references.citation: J Anat. 1990 Aug;171:187-91
references.pmid: 2081705
references.citation: Dysphagia. 2013 Sep;28(3):435-45
references.pmid: 23456326
references.citation: Biometrics. 2010 Jun;66(2):662-3
references.pmid: 20579045
references.citation: Bull Math Biol. 1996 Mar;58(2):313-65
references.pmid: 8713662
references.citation: J Hum Evol. 2003 Jun;44(6):665-83
references.pmid: 12799158
references.citation: Ann Anat. 2004 Dec;186(5-6):471-8
references.pmid: 15646280
references.citation: J Hum Evol. 2004 Jun;46(6):679-97
references.pmid: 15183670
references.citation: Mol Ecol Resour. 2011 Mar;11(2):353-7
references.pmid: 21429143
references.citation: Int J Pediatr Otorhinolaryngol. 2008 May;72(5):683-91
references.pmid: 18359094
references.citation: Auris Nasus Larynx. 2001 Apr;28(2):151-9
references.pmid: 11240323
references.citation: Auris Nasus Larynx. 1998 Sep;25(3):303-8
references.pmid: 9799998
references.citation: Am J Phys Anthropol. 2007 May;133(1):723-5
references.pmid: 17326102
references.citation: Surg Radiol Anat. 1994;16(1):31-6
references.pmid: 8047966
references.citation: Laryngoscope. 2000 Nov;110(11):1957-61
references.pmid: 11081618