title: Successful use of high-frequency spinal cord stimulation following traditional treatment failure.
abstract: BACKGROUND
  High-frequency spinal cord stimulation (HFSCS) offers an alternative treatment for chronic refractory pain syndromes nonresponsive to traditional spinal cord stimulation (SCS). Following the conflicting findings of preliminary HFSCS clinical studies performed at 5-10 kHz, this study is the first to report successful clinical usage of 1-kHz frequency SCS with a standard generator.
  
  
  METHODS
  We used HFSCS in 2 patients who had inadequate relief with traditional SCS. Patient 1 was initially programmed at 40 Hz and a pulse width of 330 μs with bipolar stimulation. After multiple setting adjustments with inadequate pain relief, the patient was reprogrammed to HFSCS at settings of 1.15 kHz, 120 μs, and 5 V. Patient 2 was initially programmed at a frequency of 1.2 kHz and a pulse width of 120 μs, which she favored over the standard setting of 40 Hz and 390 μs pulse width. HFSCS provided optimal pain alleviation and increased quality of life for both patients.
  
  
  CONCLUSIONS
  HFSCS at the frequency of 1 kHz offers a new tool for treatment of chronic pain in patients with traditional stimulation settings. Furthermore, most standard SCS batteries are capable of delivering stimulation in this frequency range.
authors.affiliation: Department of Neurosurgery, Albany Medical College, Albany, N.Y., USA.
authors.forename: Heather
authors.initials: H
authors.lastname: Smith
authors.forename: Youngwon
authors.initials: Y
authors.lastname: Youn
authors.forename: Julie G
authors.initials: JG
authors.lastname: Pilitsis
mesh_terms: D000368:Aged; D059350:Chronic Pain / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010147:Pain Measurement / Q000379:methods; D062187:Spinal Cord Stimulation / Q000379:methods* / Q000706:statistics & numerical data; D017211:Treatment Failure; D016896:Treatment Outcome