title: [Frovatriptan possibly causing acute myocardial infarction].
abstract: Globally migraine affects more than 10% of the adult population and it is treated with simple analgesics, combined with a triptan for a stronger treatment effect. Triptans cause arterial vasoconstriction, and this is a case report of vasospasm-induced acute myocardial infarction in a 61-year-old woman with frequent episodic migraine attacks treated with triptans. She was possibly also suffering from medication overuse headache. We suggest that regular frovatriptan use may have contributed to the myocardial infarction and that long-term triptan use may have caused the medication overuse headache.
authors.affiliation: Ringkøbingvej 14, st. th., 8000 Aarhus C. ole.helgestad@hotmail.com.
authors.forename: Ole Kristian
authors.initials: OK
authors.lastname: Møller-Helgestad
authors.forename: Anne Kjer
authors.initials: AK
authors.lastname: Kaltoft
authors.forename: Helge
authors.initials: H
authors.lastname: Kasch
mesh_terms: D002227:Carbazoles / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D051271:Headache Disorders, Secondary / Q000139:chemically induced; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000175:diagnosis; D017366:Serotonin Receptor Agonists / Q000009:adverse effects* / Q000627:therapeutic use; D014363:Tryptamines / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D002227:Carbazoles; D017366:Serotonin Receptor Agonists; D014363:Tryptamines; C108128:frovatriptan