title: A smart tailor-made G-clip reporter for sensitive detection of G-triplet-containing sequences.
abstract: Taking advantage of the intrinsic characteristics of G-triplet-containing sequences, a pioneering tailor-made clip-like reporter containing three-fourths of a G-quadruplex is established. The reporter can clip the G triplet in the target sequence through a recognition process to form a complete G-quadruplex structure.
authors.affiliation: Beijing National Laboratory for Molecular Sciences (BNLMS), MOE Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry, Peking University, Beijing 100871, China. zhouyl@pku.edu.cn zxx@pku.edu.cn.
authors.forename: Liang-Yuan
authors.initials: LY
authors.lastname: Cai
authors.forename: Ji
authors.initials: J
authors.lastname: Nie
authors.forename: Yi-Wei
authors.initials: YW
authors.lastname: Zhang
authors.forename: Fang-Ting
authors.initials: FT
authors.lastname: Zhang
authors.forename: Ying-Lin
authors.initials: YL
authors.lastname: Zhou
authors.forename: Xin-Xiang
authors.initials: XX
authors.lastname: Zhang
mesh_terms: D001483:Base Sequence; D015374:Biosensing Techniques / Q000379:methods*; D054856:G-Quadruplexes; D006147:Guanine; D009154:Mutation; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics*
chemical_list: D006147:Guanine