title: Primary localized tracheobronchial amyloidosis presenting with massive hemoptysis: a case report and literature review.
abstract: Primary localized tracheobronchial amyloidosis (TBA) is a rare respiratory tract dysfunction, which is a heterogeneous group of diseases involving abnormal extracellular deposition of amyloid and autologous fibrillar protein material in β-pleated sheets. A 64-year-old man was referred to our hospital because of hemoptysis. Physical examination showed decreased breath sounds in the right lung on auscultation. Chest computed tomography scan displayed multiple nodules with varied size in main bronchia around bilateral hilus of the lung. After admission, bronchoscopy was performed for this patient, and roughness of mucosa in trachea and multiple nodules in respiratory tract were observed. Through further tissue biopsy, the diagnosis of primary TBA was confirmed.
authors.affiliation: The Department of Respiratory Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, China.
authors.forename: Li-Qin
authors.initials: LQ
authors.lastname: Zhang
authors.affiliation: The Department of Respiratory Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, China.
authors.forename: Yi-Chao
authors.initials: YC
authors.lastname: Zhao
authors.affiliation: The Department of Respiratory Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, China.
authors.forename: Xiao-Wei
authors.initials: XW
authors.lastname: Wang
authors.affiliation: The Department of Respiratory Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Yang
authors.affiliation: The Department of Respiratory Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, China.
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Lu
authors.affiliation: The Department of Respiratory Medicine, Yijishan Hospital, Wannan Medical College, Wuhu, China.
authors.forename: Yu-Sheng
authors.initials: YS
authors.lastname: Cheng
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis*; D001706:Biopsy; D001984:Bronchial Neoplasms / Q000175:diagnosis; D001999:Bronchoscopy / Q000379:methods; D006469:Hemoptysis / Q000175:diagnosis*; D006801:Humans; D000075363:Immunoglobulin Light-chain Amyloidosis; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods; D014134:Tracheal Neoplasms / Q000175:diagnosis*
keywords: biopsy; bronchoscopy; hemoptysis; tracheobronchial amyloidosis