title: Antimicrobial bacterial cellulose nanocomposites prepared by in situ polymerization of 2-aminoethyl methacrylate.
abstract: Antimicrobial bacterial cellulose/poly(2-aminoethyl methacrylate) (BC/PAEM) nanocomposites were prepared by in situ radical polymerization of 2-aminoethyl methacrylate, using variable amounts of N,N-methylenebis(acrylamide) (MBA) as cross-linker. The obtained nanocomposites were characterized in terms of their structure, morphology, thermal stability, mechanical properties and antibacterial activity. The ensuing composite membranes were significantly more transparent than those of pure BC and showed improved thermal and mechanical properties. The antibacterial activity of the obtained nanocomposites was assessed towards a recombinant bioluminescent Escherichia coli and only the non-crosslinked nanocomposite (BC/PAEM) proved to have antibacterial activity.
authors.affiliation: Department of Chemistry and CICECO - Aveiro Institute of Materials, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.
authors.forename: Ana R P
authors.initials: AR
authors.lastname: Figueiredo
authors.affiliation: Department of Chemistry and CICECO - Aveiro Institute of Materials, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.
authors.forename: Andrea G P R
authors.initials: AG
authors.lastname: Figueiredo
authors.affiliation: Department of Chemistry and CICECO - Aveiro Institute of Materials, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.
authors.forename: Nuno H C S
authors.initials: NH
authors.lastname: Silva
authors.affiliation: Department of Chemistry and CICECO - Aveiro Institute of Materials, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.
authors.forename: Ana
authors.initials: A
authors.lastname: Barros-Timmons
authors.affiliation: Department of Biology and CESAM, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.
authors.forename: Adelaide
authors.initials: A
authors.lastname: Almeida
authors.affiliation: Department of Chemistry and CICECO - Aveiro Institute of Materials, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal.
authors.forename: Armando J D
authors.initials: AJ
authors.lastname: Silvestre
authors.affiliation: Department of Chemistry and CICECO - Aveiro Institute of Materials, Campus de Santiago, University of Aveiro, 3810-193 Aveiro, Portugal. Electronic address: cfreire@ua.pt.
authors.forename: Carmen S R
authors.initials: CS
authors.lastname: Freire
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D002482:Cellulose / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D008163:Luminescent Measurements; D009682:Magnetic Resonance Spectroscopy; D008689:Methacrylates / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D053761:Nanocomposites / Q000737:chemistry* / Q000633:toxicity; D058105:Polymerization; D017550:Spectroscopy, Fourier Transform Infrared; D013718:Tensile Strength; D013818:Thermogravimetry; D014961:X-Ray Diffraction
chemical_list: D000890:Anti-Infective Agents; D008689:Methacrylates; C072703:2-aminoethylmethacrylate; D002482:Cellulose
keywords: Antibacterial properties; Bacterial cellulose; Bioluminescent Escherichia coli; In situ radical polymerization; Nanocomposite membranes; Poly(2-aminoethyl methacrylate) (PAEM)