title: [Immune status of patients after splenectomy, performed for the spleen traumatic injury in remote terms and choice of preparations for its correction].
abstract: Immune status was analyzed in 28 patients in remote period after splenectomy. In accordance to immunological data obtained in splenectomy patients, inhibition of cellular chain of speciphic and natural immunity was noted on background of hyperactivation of its humoral chain with signs of autoimmune processes. In such patients, while immunomodulators selection, the mostly pronounced stimulating impact was noted in immunoglobulin; of sorbents the most binding capacity has rheopolyglukin. This opens further perspectives of postsplenectomy patients treatment, using immunomodulating and elimination correction of the disorders revealed. Expediency of application of rheopolyglukin and immunoglobulin in contents of eliminating amed immunomodulating therapy was substantiated. Studying of peculiarities of immune status constitute a perspective way in the patients, in whom various variants of organpreserving tactics while surgical interventions on spleen were applied.
authors.forename: V O
authors.initials: VO
authors.lastname: Syplyvyĭ
authors.forename: S A
authors.initials: SA
authors.lastname: Andreieshchev
authors.forename: A V
authors.initials: AV
authors.lastname: Akymenko
authors.forename: V V
authors.initials: VV
authors.lastname: Dotsenko
authors.forename: O V
authors.initials: OV
authors.lastname: Ievtushenko
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016175:B-Lymphocyte Subsets / Q000166:cytology / Q000187:drug effects / Q000276:immunology; D002648:Child; D003911:Dextrans / Q000627:therapeutic use; D005260:Female; D006801:Humans; D056724:Immunity, Humoral / Q000187:drug effects*; D007113:Immunity, Innate / Q000187:drug effects*; D007136:Immunoglobulins / Q000627:therapeutic use*; D007155:Immunologic Factors / Q000627:therapeutic use*; D056747:Immunomodulation; D016130:Immunophenotyping; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013154:Spleen / Q000187:drug effects / Q000276:immunology* / Q000293:injuries / Q000601:surgery; D013156:Splenectomy; D016176:T-Lymphocyte Subsets / Q000166:cytology / Q000187:drug effects / Q000276:immunology
chemical_list: D003911:Dextrans; D007136:Immunoglobulins; D007155:Immunologic Factors