title: Pancreatitis and portal vein thrombosis in children: the chicken or the egg causality dilemma.
abstract: BACKGROUND
  The association of pancreatitis and portal vein thrombosis (PVT) is extremely rare in children. We report on 3 cases which suggest that there may be a causal relation between the two.
  
  
  METHODS
  Clinical characteristics and evolution of 3 children with this particular condition were analyzed retrospectively. In this group of patients, the strategy consisted in opting for early surgical decompression of the portal hypertension, which was followed by a favorable outcome, not only in terms of complications related to the portal hypertension but also of a contemporaneous spontaneous regression of the concurrent pancreatic disease, in absence of any other specific management of the latter problem.
  
  
  CONCLUSIONS
  Combined PVT and pancreatitis is exceptional in children. Although this series is small, it provides insight and some evidence that the pancreatic disease might be secondary to the cavernomatous transformation of the regional venous system. More interestingly, it suggests that the appropriate management strategy should be to rapidly relieve portal hypertension after resolution of the acute phase of pancreatitis.
authors.affiliation: Hepatobiliary Surgery Unit, Department of Surgery, Bambino Gesù Children's Hospital, Roma, Italy. Electronic address: fdifra@yahoo.it.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: di Francesco
authors.affiliation: Pediatric Surgery, University of Roma Tor Vergata, Roma, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Del Prete
authors.affiliation: Hepatobiliary Surgery Unit, Department of Surgery, Bambino Gesù Children's Hospital, Roma, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Grimaldi
authors.affiliation: Hepatobiliary Radiology Unit, Department of Imaging, Bambino Gesù Children's Hospital, Roma, Italy.
authors.forename: Lidia
authors.initials: L
authors.lastname: Monti
authors.affiliation: Hepatobiliary Surgery Unit, Department of Surgery, Bambino Gesù Children's Hospital, Roma, Italy; Pediatric Surgery, University of Roma Tor Vergata, Roma, Italy.
authors.forename: Jean
authors.initials: J
authors.lastname: de Ville de Goyet
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D019299:Decompression, Surgical; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008297:Male; D010195:Pancreatitis / Q000175:diagnosis / Q000209:etiology*; D011169:Portal Vein; D020246:Venous Thrombosis / Q000150:complications* / Q000175:diagnosis / Q000601:surgery
keywords: Children; Meso-Rex bypass; Pancreatitis; Portal hypertension; Surgical strategy