title: Higher adenoma recurrence rate after left- versus right-sided colectomy for colon cancer.
abstract: BACKGROUND
  Patients with history of colonic resection for cancer have an increased risk of the development of metachronous malignant and premalignant lesions. Scanty data are reported on detection rates of premalignant lesions during colonoscopy surveillance in this setting.
  
  
  OBJECTIVE
  To assess the risk of metachronous precancerous lesions developing in patients with previous colonic surgery for cancer according to the resection type.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  Two academic centers in Italy.
  
  
  METHODS
  A total of 441 patients; 256 with previous left-sided colectomy (LCR) (LCR group) and 185 with previous right-sided colectomy (RCR) (RCR group).
  
  
  METHODS
  Second surveillance colonoscopy.
  
  
  METHODS
  Polyp and adenoma detection rates.
  
  
  RESULTS
  At least 1 adenoma was diagnosed in 76 of 256 patients (30% adenoma detection rate) and in 35 of 185 patients (19% adenoma detection rate) in the LCR and RCR groups, respectively (P=.014), yielding an odds ratio of 1.83 (95% confidence interval, 1.16-2.89). Corresponding figures for the polyp detection rate were 39% and 25%, respectively (P=.002; odds ratio 1.97; 95% confidence interval, 1.30-3.00).
  
  
  CONCLUSIONS
  Retrospective study with colonoscopy baseline information missing.
  
  
  CONCLUSIONS
  Patients who have undergone LCR are at higher risk of the development of adenomas than those who have undergone RCR. If this result is confirmed by large prospective studies, surveillance programs could be targeted according to the type of colonic resection, with longer intervals for patients with previous RCR compared with LCR.
authors.affiliation: Department of Medical and Surgical Sciences, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Fuccio
authors.affiliation: Digestive Endoscopy Unit, Catholic University, Rome, Italy.
authors.forename: Cristiano
authors.initials: C
authors.lastname: Spada
authors.affiliation: Department of Medical and Surgical Sciences, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Frazzoni
authors.affiliation: Division of Endoscopy, Valduce Hospital, Como, Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Paggi
authors.affiliation: Digestive Endoscopy Unit, Catholic University, Rome, Italy.
authors.forename: Giovanna
authors.initials: G
authors.lastname: Vitale
authors.affiliation: Department of Medical and Surgical Sciences, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
authors.forename: Liboria
authors.initials: L
authors.lastname: Laterza
authors.affiliation: Division of Endoscopy, S. Maria delle Croci Hospital, Ravenna, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Mussetto
authors.affiliation: Division of Oncology, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
authors.forename: Fabiola
authors.initials: F
authors.lastname: Rojas
authors.affiliation: Division of Endoscopy, Valduce Hospital, Como, Italy.
authors.forename: Franco
authors.initials: F
authors.lastname: Radaelli
authors.affiliation: Digestive Endoscopy Unit, Catholic University, Rome, Italy.
authors.forename: Cesare
authors.initials: C
authors.lastname: Hassan
authors.affiliation: Digestive Endoscopy Unit, Catholic University, Rome, Italy.
authors.forename: Lucio
authors.initials: L
authors.lastname: Petruzziello
authors.affiliation: Digestive Pathophysiology Unit, Baggiovara Hospital, Modena, Italy.
authors.forename: Marzio
authors.initials: M
authors.lastname: Frazzoni
mesh_terms: D000236:Adenoma / Q000175:diagnosis* / Q000601:surgery; D000368:Aged; D003082:Colectomy; D003106:Colon / Q000601:surgery*; D003110:Colonic Neoplasms / Q000175:diagnosis* / Q000601:surgery; D003111:Colonic Polyps / Q000175:diagnosis*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis*; D012189:Retrospective Studies