title: Intrinsic peroxidase-like catalytic activity of nitrogen-doped graphene quantum dots and their application in the colorimetric detection of H2O2 and glucose.
abstract: In this paper, the highly intrinsic peroxidase-like catalytic activity of nitrogen-doped graphene quantum dots (N-GQDs) is revealed. This activity was greatly dependent on pH, temperature and H2O2 concentration. The experimental results showed that the stable N-GQDs could be used for the detection of H2O2 and glucose over a wide range of pH and temperature, offering a simple, highly selective and sensitive approach for their colorimetric sensing. The linearity between the analyte concentration and absorption ranged from 20 to 1170 μM for H2O2 and 25 to 375 μM for glucose with a detection limit of 5.3 μM for H2O2 and 16 μM for glucose. This assay was also successfully applied to the detection of glucose concentrations in diluted serum and fruit juice samples.
authors.affiliation: Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Lin
authors.affiliation: Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Xinhong
authors.initials: X
authors.lastname: Song
authors.affiliation: Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Yiying
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Mingcong
authors.initials: M
authors.lastname: Rong
authors.affiliation: Xiamen Huaxia College, Xiamen 361024, China.
authors.forename: Tingting
authors.initials: T
authors.lastname: Zhao
authors.affiliation: Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Yiru
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China.
authors.forename: Yaqi
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: Department of Chemistry and the MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China; State Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361005, China. Electronic address: xichen@xmu.edu.cn.
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry; D001786:Blood Glucose / Q000032:analysis; D002384:Catalysis; D003124:Colorimetry / Q000379:methods*; D000067030:Fruit and Vegetable Juices / Q000032:analysis; D005947:Glucose / Q000032:analysis*; D006108:Graphite / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D057230:Limit of Detection; D009584:Nitrogen / Q000737:chemistry*; D009195:Peroxidase / Q000378:metabolism*; D045663:Quantum Dots / Q000737:chemistry*; D013696:Temperature
chemical_list: D001786:Blood Glucose; D006108:Graphite; D006861:Hydrogen Peroxide; D009195:Peroxidase; D005947:Glucose; D009584:Nitrogen
keywords: Colorimetric detection; H(2)O(2) and glucose sensing; Intrinsic peroxidase-like catalytic activity; Nitrogen-doped graphene quantum dots