title: Analysis on early detection of lung cancer by PET/CT scan.
abstract: BACKGROUND
  This systemic analysis was conducted to to evaluate the application value of positron emission tomography/computed tomography (PET/CT) in early diagnosis of lung cancer.
  
  
  METHODS
  Clinical studies evaluating the application value of PET/CT for patients underwent PET/CT imaging. The histological diagnosis served as the standard of truth.
  
  
  RESULTS
  Four clinical studies which including 1330 patients with pulmonary space- occupying lesions were considered eligible for inclusion. Systemic analysis suggested that, in all 1330 patients, pooled sensitivity was 98.7% (1313.2/1330) and specificity was 58.2%(276.85/476).
  
  
  CONCLUSIONS
  This systemic analysis suggests that integrated PET/CT imaging provides high sensitivity, and reasonably high specificity, and could be applied for early diagnosis of lung cancer.
authors.affiliation: Department of Nuclear Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China E-mail : redflag963@126.com.
authors.forename: Huo-Qiang
authors.initials: HQ
authors.lastname: Wang
authors.forename: Long
authors.initials: L
authors.lastname: Zhao
authors.forename: Juan
authors.initials: J
authors.lastname: Zhao
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
mesh_terms: D055088:Early Detection of Cancer / Q000379:methods*; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D015201:Meta-Analysis as Topic; D064847:Multimodal Imaging / Q000379:methods*; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography / Q000379:methods*; D011379:Prognosis; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D014018:Tissue Distribution; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18