title: Assessment of the body composition and parameters of the cardiovascular risk in juvenile idiopathic arthritis.
abstract: The study was aimed to evaluate cardiovascular risk parameters, body mass index (BMI) centiles for sex and age, and body fat percentage using the electric bioimpedance method in children with juvenile idiopathic arthritis (JIA). 30 children with JIA participated in the study. A control group included 20 children. Patients were well matched for the age and sex. The body mass and body fat percentage were determined using the segmental body composition analyser; the BMI centiles were determined. All patients had the following parameters determined: lipid profile, hsCRP, homocysteine, and IL-6. The intima media thickness (IMT) was measured. Patients with JIA had significantly lower body weight, BMI, and the BMI centile compared to the control group. The IL-6 levels were significantly higher in patients with JIA compared to the control group. There were no differences between two groups with regard to the lipid profile, % content of the fat tissue, homocysteine levels, hsCRP, and IMT. Further studies are necessary to search for reasons for lower BMI and BMI centile in children with JIA and to attempt to answer the question of whether lower BMI increases the cardiovascular risk in these patients, similarly as in patients with rheumatoid arthritis (RA).
authors.affiliation: Paediatric Clinic of Rheumatology, Institute of Rheumatology, Spartanska 1, 02-637 Warsaw, Poland.
authors.forename: Ewa
authors.identifier: 0000-0003-2765-9609
authors.initials: E
authors.lastname: Jednacz
authors.affiliation: Paediatric Clinic of Rheumatology, Institute of Rheumatology, Spartanska 1, 02-637 Warsaw, Poland.
authors.forename: Lidia
authors.identifier: 0000-0002-9738-8923
authors.initials: L
authors.lastname: Rutkowska-Sak
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000293:Adolescent; D001171:Arthritis, Juvenile / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology*; D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology*; D002319:Cardiovascular System / Q000378:metabolism / Q000503:physiopathology; D059168:Carotid Intima-Media Thickness; D016022:Case-Control Studies; D005260:Female; D006710:Homocysteine / Q000378:metabolism; D006801:Humans; D015850:Interleukin-6 / Q000378:metabolism; D008055:Lipids / Q000502:physiology; D008297:Male; D012306:Risk; D012307:Risk Factors
chemical_list: D015850:Interleukin-6; D008055:Lipids; D006710:Homocysteine; D002097:C-Reactive Protein
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