title: Associations of the major international high-risk resistant clones and virulent clones with specific ompK36 allele groups in Klebsiella pneumoniae in Taiwan.
abstract: This study was conducted to investigate the association between ompK36 variants and international high-risk clones in Klebsiella pneumoniae. Fifty-nine sequence types (STs) divided into four ompK36 allele groups (groups A to D) were identified among 185 K. pneumoniae isolates. The major high-risk clones (29 ST11, 13 ST15, 7 ST37 and 1 ST147 isolates) were assigned to group A, while 6 STs (15 ST23, 2 ST65, 3 ST86, 1 ST163, 1 ST373 and 2 ST375 isolates) associated with pyogenic liver abscess were assigned to group C. The genotyping assay developed in this study may be useful for screening of epidemic STs.
authors.affiliation: Department of Pathology, National Cheng Kung University College of Medicine and Hospital, Taiwan.
authors.forename: J J
authors.initials: JJ
authors.lastname: Yan
authors.affiliation: Department of Internal Medicine, National Cheng Kung University College of Medicine and Hospital, Taiwan.
authors.forename: M C
authors.initials: MC
authors.lastname: Wang
authors.affiliation: Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Taiwan.
authors.forename: P X
authors.initials: PX
authors.lastname: Zheng
authors.affiliation: Department of Pathology, National Cheng Kung University College of Medicine and Hospital, Taiwan ; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Taiwan.
authors.forename: L H
authors.initials: LH
authors.lastname: Tsai
authors.affiliation: Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Taiwan.
authors.forename: J J
authors.initials: JJ
authors.lastname: Wu
keywords: High-risk clones; Klebsiella pneumoniae; multilocus sequence typing; pyogenic liver abscess; sequence types
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