title: Vascular management during live donor nephrectomy: an online survey among transplant surgeons.
abstract: In 2006, a survey from the American Society of Transplant Surgeons disclosed significant and sometimes fatal hemorrhagic events in live donor nephrectomies (LDN) related to failure of clips, leading to the contraindication of the Weck® Hem-o-lok® clip for control of the renal artery during LDN. A survey regarding vascular control techniques, their perceived safety ratings and their failures was sent to 645 European Society for Organ Transplantation members who profiled their profession as "surgeon" and selected "kidney" as organ type. Two hundred forty-three (41%) members responded, of whom 171 (63.3%) independently perform LDN. Their responses were analyzed. For arterial and venous vascular control, the GIA™ and TA™stapler are used most frequently, and were rated the safest. Of the 121 reported hemorrhagic events, slippage and dislodgement of clips occurred at least 58 times, while stapler malfunction occurred at least 40 times. One donor death from hemorrhage related to clip dysfunction was reported. Hemorrhagic complications of LDN with fatal and non-fatal outcomes still occur. Strikingly, many surgeons do not use the vascular closing technique that they consider most safe. Failure of non-transfixion techniques is associated with greater risks for the donor. Control of major vessels in LDN must employ transfixion techniques for optimal donor safety.
authors.affiliation: Division of HPB & Transplant Surgery, Department of Surgery, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Janki
authors.affiliation: Division of HPB & Transplant Surgery, Department of Surgery, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
authors.forename: D
authors.initials: D
authors.lastname: Verver
authors.affiliation: Division of HPB & Transplant Surgery, Department of Surgery, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
authors.forename: K W J
authors.initials: KW
authors.lastname: Klop
authors.affiliation: New York Organ Donor Network, New York, NY.
authors.forename: A L
authors.initials: AL
authors.lastname: Friedman
authors.affiliation: Department of Surgery, University of Florida Health Sciences Center, Jacksonville, FL.
authors.forename: T G
authors.initials: TG
authors.lastname: Peters
authors.affiliation: Department of Surgery, Columbia University, New York, NY.
authors.forename: L E
authors.initials: LE
authors.lastname: Ratner
authors.affiliation: Division of HPB & Transplant Surgery, Department of Surgery, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
authors.forename: J N M
authors.initials: JN
authors.lastname: Ijzermans
authors.affiliation: Division of HPB & Transplant Surgery, Department of Surgery, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
authors.forename: F J M F
authors.initials: FJ
authors.lastname: Dor
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000601:surgery*; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D009862:Online Systems; D061214:Patient Safety; D012307:Risk Factors; D066231:Surgeons / Q000706:statistics & numerical data*; D013525:Surgical Instruments / Q000009:adverse effects; D013528:Surgical Staplers / Q000009:adverse effects; D011795:Surveys and Questionnaires; D013537:Sutures / Q000009:adverse effects
keywords: clinical research / practice; complication: surgical / technical; donor nephrectomy; kidney transplantation / nephrology