title: Alcohol intake measured by phosphatidylethanol in blood and the lifetime drinking history interview are correlated with the extent of psoriasis.
abstract: BACKGROUND
  Psoriasis has been reported to be associated with alcohol consumption.
  
  
  OBJECTIVE
  To investigate the level of alcohol intake in individuals with psoriasis and correlate intake with the extent of disease and pruritus.
  
  
  METHODS
  Twenty-nine outpatients (15 females and 14 males) with stable chronic plaque psoriasis of moderate severity were recruited. The Psoriasis Area and Severity Index (PASI) and the degree of pruritus (visual analogue scale) were compared with measures of drinking habits as determined by the Lifetime Drinking History (LDH), the Alcohol Use Disorders Identification Test and whole-blood phosphatidylethanol (PEth), an alcohol-specific biomarker.
  
  
  RESULTS
  The majority of patients were social drinkers with moderate alcohol consumption as determined by PEth and LDH. Alcohol consumption correlated significantly with the PASI score. There was no correlation between alcohol use and pruritus.
  
  
  CONCLUSIONS
  The level of alcohol consumption is correlated with the extent of psoriasis.
authors.affiliation: Department of Dermatology and Venereology, Södersjukhuset, Stockholm, Sweden.
authors.forename: Linnea
authors.initials: L
authors.lastname: Zou
authors.forename: Sol-Britt
authors.initials: SB
authors.lastname: Lonne-Rahm
authors.forename: Anders
authors.initials: A
authors.lastname: Helander
authors.forename: Knut
authors.initials: K
authors.lastname: Stokkeland
authors.forename: Johan
authors.initials: J
authors.lastname: Franck
authors.forename: Klas
authors.initials: K
authors.lastname: Nordlind
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000368:Aged; D000428:Alcohol Drinking / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D002648:Child; D005260:Female; D020404:Glycerophospholipids / Q000097:blood*; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D011537:Pruritus / Q000209:etiology*; D011565:Psoriasis / Q000209:etiology / Q000473:pathology*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D015415:Biomarkers; D020404:Glycerophospholipids; C051521:phosphatidylethanol