title: Anomalous optical coherence tomography findings in Wyburn-Mason syndrome and isolated retinal arteriovenous malformation.
abstract: We report 2 cases of unilateral retinal arteriovenous malformation (AVM) with previously unreported anomalies of the inner retinal layers detected on spectral domain optical coherence tomography (SD-OCT): a 5-year-old girl with a large unilateral retinal AVM, ipsilateral visual acuity of 20/200, and ipsilateral intracranial AVM; and a 10-year-old boy with a large unilateral retinal AVM, ipsilateral visual acuity of 20/20, ipsilateral temporal visual field defects, and no intracranial AVM. Both macular SD-OCT findings showed multiple large inner retinal vessels that created a prominent shadowing artifact, retinal thickening, and speckling and heterogeneity of inner retinal layers.
authors.affiliation: Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire. Electronic address: margaret.j.chowaniec@dartmouth.edu.
authors.forename: Margaret J
authors.initials: MJ
authors.lastname: Chowaniec
authors.affiliation: University of Nebraska Medical Center, Department of Ophthalmology and Visual Sciences, Omaha, Nebraska.
authors.forename: Donny W
authors.initials: DW
authors.lastname: Suh
authors.affiliation: University of Iowa and The Carver College of Medicine, Department of Ophthalmology and Visual Sciences, Iowa City, Iowa.
authors.forename: H Culver
authors.initials: HC
authors.lastname: Boldt
authors.affiliation: University of Iowa and The Carver College of Medicine, Department of Pediatrics (Neurology), Iowa City, Iowa.
authors.forename: Steven F
authors.initials: SF
authors.lastname: Stasheff
authors.affiliation: Albany Medical College, Department of Ophthalmology, Albany, New York.
authors.forename: Paul M
authors.initials: PM
authors.lastname: Beer
authors.affiliation: Albany Medical College, Department of Ophthalmology, Albany, New York.
authors.forename: Gerard P
authors.initials: GP
authors.lastname: Barry
mesh_terms: D001164:Arteriovenous Fistula / Q000175:diagnosis* / Q000503:physiopathology; D001165:Arteriovenous Malformations / Q000175:diagnosis* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D020752:Neurocutaneous Syndromes / Q000175:diagnosis* / Q000503:physiopathology; D012161:Retinal Artery / Q000002:abnormalities*; D012169:Retinal Vein / Q000002:abnormalities*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology