title: Gastrointestinal manifestations of Henoch-Schonlein purpura: A report of two cases.
abstract: Henoch-Schonlein purpura (HSP) is a small vessel vasculitis mediated by type III hypersensitivity with deposition of IgA immune complex in the walls of vessels. It is a multi-system disorder characterized by palpable purpura, arthritis, glomerulonephritis and gastrointestinal manifestations and commonly occurs in children and young adults. The patients with gastrointestinal involvement usually present with colicky abdominal pain, vomiting and melena. The imaging findings include multifocal bowel thickening with mucosal hyperenhancement, presence of skip areas, mesenteric vascular engorgement, with involvement of unusual sites like stomach, duodenum and rectum. These imaging findings in a child or young adult with appropriate clinical findings could suggest HSP.
authors.affiliation: Parameswaran Prathiba Rajalakshmi, Department of Radiology, Sree Balaji Medical College and Hospital, Chromepet, Chennai 600044, Tamil Nadu, India.
authors.forename: Parameswaran
authors.initials: P
authors.lastname: Prathiba Rajalakshmi
authors.affiliation: Parameswaran Prathiba Rajalakshmi, Department of Radiology, Sree Balaji Medical College and Hospital, Chromepet, Chennai 600044, Tamil Nadu, India.
authors.forename: Kalyanasundaram
authors.initials: K
authors.lastname: Srinivasan
keywords: Bowel thickening; Henoch-Schonlein purpura; Skip areas; Vasculitis
references.citation: AJR Am J Roentgenol. 1997 Apr;168(4):965-8
references.pmid: 9124151
references.citation: Arch Dis Child Educ Pract Ed. 2008 Feb;93(1):1-8
references.pmid: 18208978
references.citation: World J Radiol. 2014 May 28;6(5):130-8
references.pmid: 24876917
references.citation: Chang Gung Med J. 2004 Mar;27(3):175-81
references.pmid: 15148994
references.citation: Am J Gastroenterol. 1986 Mar;81(3):195-8
references.pmid: 3485374
references.citation: Gastroenterol Res Pract. 2010;2010:597648
references.pmid: 20508739
references.citation: AJR Am J Roentgenol. 2006 Oct;187(4):W396-8
references.pmid: 16985111
references.citation: Arthritis Rheum. 1990 Aug;33(8):1114-21
references.pmid: 2202310
references.citation: Insights Imaging. 2014 Apr;5(2):195-208
references.pmid: 24407923
references.citation: Radiographics. 2008 May-Jun;28(3):727-46
references.pmid: 18480481
references.citation: Radiographics. 2000 May-Jun;20(3):779-94
references.pmid: 10835128