title: CHILD Syndrome: Successful Treatment of Skin Lesions with Topical Simvastatin/Cholesterol Ointment--A Case Report.
abstract: CHILD syndrome is a rare X-linked dominant condition that presents with congenital hemidysplasia, Ichthyosiform erythroderma, and limb defects in affected patients. We report the case of a 10-year-old girl treated with topical simvastatin and cholesterol ointment, after which her skin lesions significantly improved within the first 30 days of treatment.
authors.affiliation: First Department of Pediatrics, University of Athens and Aghia Sofia Children's Hospital, Athens, Greece.
authors.forename: Alexios
authors.initials: A
authors.lastname: Alexopoulos
authors.affiliation: First Department of Pediatrics, University of Athens and Aghia Sofia Children's Hospital, Athens, Greece.
authors.forename: Talia
authors.initials: T
authors.lastname: Kakourou
mesh_terms: D000015:Abnormalities, Multiple / Q000188:drug therapy*; D000287:Administration, Topical; D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D002648:Child; D002784:Cholesterol / Q000627:therapeutic use*; D005260:Female; D040181:Genetic Diseases, X-Linked / Q000188:drug therapy*; D006801:Humans; D016113:Ichthyosiform Erythroderma, Congenital / Q000188:drug therapy*; D017512:Lichenoid Eruptions / Q000188:drug therapy / Q000209:etiology; D017880:Limb Deformities, Congenital / Q000188:drug therapy*; D008052:Lipid Metabolism, Inborn Errors / Q000150:complications; D009824:Ointments; D019821:Simvastatin / Q000627:therapeutic use*
chemical_list: D000924:Anticholesteremic Agents; D009824:Ointments; D002784:Cholesterol; D019821:Simvastatin