title: Uterine primitive neuroectodermal tumor.
abstract: Primitive neuroectodermal tumors are fairly rare in uterus. A case of uterine body primitive neuroectodermal tumor in a 32-year-old Iranian woman is presented. The patient was admitted with abdominal pain and fever and underwent emergency exploratory surgery with total abdominal hysterectomy, bilateral salpingo-oophorectomy, and pelvic lymph node dissection. Posterior wall of the uterus was necrotic and ruptured and a huge tumor disrupted the uterine body. The tumor was strongly positive for CD99, NSE, and chromogranin; No reaction was seen for CD10, CD45 and myogenin. To the best of our knowledge, this is the first report of an uterine body primitive neuroectodermal tumor and the second report of uterine primitive neuroectodermal tumor from Iran.
authors.affiliation: Department of Gynecology Oncology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran. sseifirad@gmail.com.
authors.forename: Soheila
authors.initials: S
authors.lastname: Aminimoghaddam
authors.affiliation: Endocrinology and Metabolism Research Center (EMRC), Endocrinology and Metabolism Research Institute (EMRI), Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran.
authors.forename: Soroush
authors.initials: S
authors.lastname: Seifirad
authors.affiliation: Department of Gynecology Oncology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Golbahar
authors.initials: G
authors.lastname: Abbasi Dezfouli
authors.affiliation: Department of Gynecology Oncology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Neda
authors.initials: N
authors.lastname: Abbasi
authors.affiliation: Department of Pathology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Zare Mehrjardi
authors.affiliation: Department of Gynecology Oncology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Seyed Mohsen
authors.initials: SM
authors.lastname: Razavi
authors.affiliation: Medical Student, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Mahmoudzadeh
mesh_terms: D000328:Adult; D015415:Biomarkers; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008279:Magnetic Resonance Imaging; D018242:Neuroectodermal Tumors, Primitive / Q000473:pathology* / Q000628:therapy; D010052:Ovariectomy; D014594:Uterine Neoplasms / Q000473:pathology* / Q000628:therapy; D014599:Uterus / Q000473:pathology*
chemical_list: D015415:Biomarkers