title: A restless abdomen and propriospinal myoclonus like at sleep onset: an unusual overlap syndrome.
abstract: We report for the first time the association between restless abdomen, a phenotypic variant of restless legs syndrome in which symptoms are limited to the abdomen, and propriospinal myoclonus at sleep onset causing severe insomnia. The treatment with a low-dosage of dopaminergic drug (pramipexole) induced the immediate disappearance of both symptoms, which was documented by video-polysomnography.
authors.affiliation: Department of Biomedical and Neuromotor Sciences, University of Bologna, Neurology Unit, S. Orsola-Malpighi Hospital, AOU Bologna, Italy.
authors.forename: Simone
authors.initials: S
authors.lastname: Baiardi
authors.affiliation: Department of Biomedical and Neuromotor Sciences, University of Bologna, Neurology Unit, S. Orsola-Malpighi Hospital, AOU Bologna, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: La Morgia
authors.affiliation: Department of Biomedical and Neuromotor Sciences, University of Bologna, Neurology Unit, S. Orsola-Malpighi Hospital, AOU Bologna, Italy.
authors.forename: Susanna
authors.initials: S
authors.lastname: Mondini
authors.affiliation: Department of Biomedical and Neuromotor Sciences, University of Bologna, Neurology Unit, S. Orsola-Malpighi Hospital, AOU Bologna, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Cirignotta
mesh_terms: D000005:Abdomen / Q000503:physiopathology*; D000369:Aged, 80 and over; D052160:Benzothiazoles / Q000627:therapeutic use*; D015259:Dopamine Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009207:Myoclonus / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D017286:Polysomnography; D000077487:Pramipexole; D011595:Psychomotor Agitation / Q000150:complications / Q000188:drug therapy* / Q000209:etiology; D012148:Restless Legs Syndrome / Q000188:drug therapy; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy* / Q000209:etiology; D016896:Treatment Outcome; D014743:Videotape Recording
chemical_list: D052160:Benzothiazoles; D015259:Dopamine Agents; D000077487:Pramipexole
references.citation: Sleep. 2001 Nov 1;24(7):835-43
references.pmid: 11683486
references.citation: Brain. 1991 Feb;114 ( Pt 1A):197-214
references.pmid: 1998882
references.citation: Mov Disord. 2013 Nov;28(13):1868-73
references.pmid: 24105950
references.citation: Neurology. 1992 Aug;42(8):1591-5
references.pmid: 1641156
references.citation: Mov Disord. 2005 Oct;20(10):1323-9
references.pmid: 16007657
references.citation: Mov Disord. 1997 Jan;12(1):66-72
references.pmid: 8990056
references.citation: Neurology. 2009 Apr 14;72(15):1301-9
references.pmid: 19365051
references.citation: Neurology. 2014 Nov 11;83(20):1862-70
references.pmid: 25305154
references.citation: Sleep Med. 2003 Mar;4(2):101-19
references.pmid: 14592341
references.citation: Neurology. 2011 Sep 27;77(13):1283-6
references.pmid: 21917771
references.citation: Neurophysiol Clin. 2006 Sep-Dec;36(5-6):351-5
references.pmid: 17336781
references.citation: Parkinsonism Relat Disord. 2014 Jun;20(6):596-9
references.pmid: 24661468