title: Arthroscopic partial anterior synovectomy of the knee on patients with haemophilia.
abstract: OBJECTIVE
  This study assessed the results of two-portal knee arthroscopic synovectomy in terms of bleeding recurrence, knee function, quality of life (QOL), and radiographic staging in a prospective case series of patients with haemophilia.
  
  
  METHODS
  Nine knees from eight patients (median age 16.1 years; range 9.6-25 years) with haemophilia and recurrent knee haemarthrosis were prospectively evaluated. Yearly recurrence of bleeding was evaluated once a year for 5 years postoperatively. Range of motion (ROM) and radiographic staging, as well as results of the short form (SF)-36 and subjective knee form of the International Knee Documentation Committee (IKDC) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaires, were evaluated before surgery and at the end of follow-up.
  
  
  RESULTS
  Mean bleeding recurrence was significantly reduced during the 5-year follow-up period. Questionnaire results showed significant improvements (IKDC P = 0.015, WOMAC P = 0.011, and SF-36 P = 0.023), whereas ROM was not significantly affected. Arthropathy progressed from Arnold-Hilgartner radiographic stage III to stage IV (P = 0.0082).
  
  
  CONCLUSIONS
  Two-portal knee arthroscopic synovectomy was effective at reducing bleeding recurrence and improving knee function and QOL in patients with haemophilia, but did not interrupt the progression of radiographic changes.
authors.forename: Adriano Marques
authors.initials: AM
authors.lastname: de Almeida
authors.forename: Marcia Uchoa
authors.initials: MU
authors.lastname: de Rezende
authors.forename: Felippi Guizardi
authors.initials: FG
authors.lastname: Cordeiro
authors.forename: Paula Ribeiro
authors.initials: PR
authors.lastname: Villaça
authors.forename: Elbio Antonio
authors.initials: EA
authors.lastname: D'Amico
authors.forename: Arnaldo José
authors.initials: AJ
authors.lastname: Hernandez
authors.forename: Gilberto Luis
authors.initials: GL
authors.lastname: Camanho
mesh_terms: D000293:Adolescent; D000328:Adult; D001182:Arthroscopy / Q000379:methods; D002648:Child; D006305:Health Status Indicators; D006395:Hemarthrosis / Q000209:etiology / Q000601:surgery*; D006467:Hemophilia A / Q000150:complications; D006801:Humans; D007719:Knee Joint / Q000601:surgery*; D008297:Male; D011182:Postoperative Care; D011446:Prospective Studies; D011788:Quality of Life; D016059:Range of Motion, Articular; D012008:Recurrence; D000074402:Synovectomy; D016896:Treatment Outcome; D055815:Young Adult
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