title: DEEP Study: does EQ-5D-5L measure the impacts of persistent oro-facial pain?
abstract: The EQ-5D-5L is a generic quality of life (QOL) measure widely used throughout the world, which has the advantage that it allows health-state preferences to be elicited. The aim of this study was to examine whether: a) variation in the standardised reference period for EQ-5D-5L from 'today' to 'the last month' had a minimal clinically meaningful difference; (b) EQ-5D-5L had convergent validity with a multidimensional pain measure in quantifying the impacts of pain. As part of a larger study into the effectiveness and efficiency of care pathways for persistent orofacial pain (POFP) (http://research.ncl.ac.uk/deepstudy), participants with POFP (n = 100) completed two versions of the EQ-5D-5L at the same time with different reference periods ('today' vs. 'last month'). Participants also completed the first section of the West Haven-Yale Multidimensional Pain Inventory (v3) to assess convergent validity. Two-tailed nonparametric inferential statistics, intra-class correlation coefficients (ICC), and within-subject change scores were used to compare the two EQ-5D-5L versions. Convergent validity was assessed using Spearman's rho correlation coefficients. Health-state valuations were significantly different (P < 0.01), and there was good similarity between the two versions' ICC 0.86 (95% CI 0.79-0.91). The within-subject mean change was 0.03 (95% CI 0.01-0.06). For convergent validity, all relationships were significant (P < 0.05) and in the expected directions. EQ-5D-5L demonstrates sufficient convergent validity to be used with POFP, and a change in the standard reference period may be unnecessary if a multidimensional pain measure is also used.
authors.affiliation: Centre for Oral Health Research, Newcastle University, Newcastle-upon-Tyne, NE2 4BW, UK.|Institute of Health & Society, Newcastle University, Newcastle-upon-Tyne, UK.
authors.forename: J
authors.initials: J
authors.lastname: Durham
authors.affiliation: Centre for Oral Health Research, Newcastle University, Newcastle-upon-Tyne, NE2 4BW, UK.|Institute of Health & Society, Newcastle University, Newcastle-upon-Tyne, UK.
authors.forename: J G
authors.initials: JG
authors.lastname: Steele
authors.affiliation: Institute of Health & Society, Newcastle University, Newcastle-upon-Tyne, UK.
authors.forename: M
authors.initials: M
authors.lastname: Breckons
authors.affiliation: Centre for Oral Health Research, Newcastle University, Newcastle-upon-Tyne, NE2 4BW, UK.
authors.forename: W
authors.initials: W
authors.lastname: Story
authors.affiliation: Institute of Health & Society, Newcastle University, Newcastle-upon-Tyne, UK.
authors.forename: L
authors.initials: L
authors.lastname: Vale
mesh_terms: D059350:Chronic Pain / Q000523:psychology*; D005157:Facial Pain / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement / Q000379:methods*; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires / Q000592:standards*
keywords: EQ-5D; facial pain; outcome; pain; persistent oro-facial pain; quality of life
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