title: Fluorescent Probes Used for Detection of Hydrogen Peroxide under Biological Conditions.
abstract: Hydrogen peroxide is a well-established precursor of reactive oxygen and nitrogen species that are known to contribute to oxidative stress-the crucial factor responsible for the course of a wide range of phy-sicochemical processes as well as the genesis of various diseases, such as cancer and neurodegenerative disorders. Thus, the development of sensitive and selective methods for the detection and quantitative determination of hydrogen peroxide is of great importance in monitoring the in vivo production of that species and elucidating its biological functions. This review highlights the progress that has been made in the development of fluorescent and luminescent probes (excluding nanoparticles) employed to monitor hydrogen peroxide under biological conditions. Attention was focused on probes developed in the past 10 years.
authors.affiliation: a Faculty of Chemistry, University of Gdansk , Gdansk , Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Żamojć
authors.affiliation: a Faculty of Chemistry, University of Gdansk , Gdansk , Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Zdrowowicz
authors.affiliation: a Faculty of Chemistry, University of Gdansk , Gdansk , Poland.
authors.forename: Dagmara
authors.initials: D
authors.lastname: Jacewicz
authors.affiliation: a Faculty of Chemistry, University of Gdansk , Gdansk , Poland.
authors.forename: Dariusz
authors.initials: D
authors.lastname: Wyrzykowski
authors.affiliation: a Faculty of Chemistry, University of Gdansk , Gdansk , Poland.
authors.forename: Lech
authors.initials: L
authors.lastname: Chmurzyński
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000032:analysis* / Q000378:metabolism; D015394:Molecular Structure
chemical_list: D005456:Fluorescent Dyes; D006861:Hydrogen Peroxide
keywords: Boronate probes; detection of hydrogen peroxide; fluorescent probes; nonboronate probes; reactive oxygen species