title: [Cardiovascular diseases in the population of industrial towns and environmental factors].
abstract: OBJECTIVE
  To study the influence of environmental factors (EFs) on the development of cardiovascular diseases in the population of industrial towns of the Republic of Kazakhstan.
  
  
  METHODS
  The investigation covered an 18-59-year-old adult population who had been living in the urbanized areas of the Republic of Kazakhstan for at least 10 years, who worked in harmless conditions and were unregistered as having chronic diseases. At Stage 1, screening (a therapist's examination, blood general and immunological tests, and electrocardiography) was carried out for risk group persons who underwent in-depth clinical examination (blood biochemical test) at Stage 2.
  
  
  RESULTS
  Multivariate statistical analysis has revealed that the development of hypertension is associated with the high concentration of sulfur dioxide in atmospheric air, copper in dust sediments, and zinc in soil and that of coronary heart disease (CHD) is related to the high levels of nitrogen dioxide in atmospheric air and zinc in dust sediments.
  
  
  CONCLUSIONS
  Based on pathogenetic and statistical data and information available in the literature, hypertension and CHD are referred to as the diseases that may result from the influence of EFs.
authors.affiliation: Karaganda State Medical University, Karaganda, Republic of Kazakhstan.
authors.forename: L K
authors.initials: LK
authors.lastname: Ibraeva
authors.affiliation: National Center for Industrial Hygiene and Occupational Diseases, Ministry for Labor and Social Protection of the Republic of Kazakhstan, Astana, Republic of Kazakhstan.
authors.forename: G N
authors.initials: GN
authors.lastname: Azhimetova
authors.affiliation: National Center for Industrial Hygiene and Occupational Diseases, Ministry for Labor and Social Protection of the Republic of Kazakhstan, Astana, Republic of Kazakhstan.
authors.forename: A U
authors.initials: AU
authors.lastname: Amanbekova
authors.affiliation: National Center for Industrial Hygiene and Occupational Diseases, Ministry for Labor and Social Protection of the Republic of Kazakhstan, Astana, Republic of Kazakhstan.
authors.forename: R E
authors.initials: RE
authors.lastname: Bakirova
mesh_terms: D000293:Adolescent; D000328:Adult; D000393:Air Pollutants / Q000032:analysis* / Q000737:chemistry; D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000453:epidemiology*; D002947:Cities; D004781:Environmental Exposure / Q000009:adverse effects* / Q000032:analysis; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D007221:Industry; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D012426:Russia / Q000453:epidemiology; D012989:Soil Pollutants / Q000032:analysis* / Q000737:chemistry; D055815:Young Adult
chemical_list: D000393:Air Pollutants; D012989:Soil Pollutants