title: Performance of Alere Determine HIV-1/2 Ag/Ab Combo rapid test for acute HIV infection: a case report.
abstract: We describe a case of symptomatic acute HIV infection in a young man where a fourth-generation rapid screening test combining HIV-specific antibody and p24 antigen was negative. In highly suspicious cases of acute HIV infection, plasma HIV RNA assays together with conventional, non-rapid screening tests should be used.
authors.affiliation: Unit of Infectious Diseases, Department of General Medicine; Unit of Microbiology, Department of Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Lanzafame
authors.affiliation: Unit of Infectious Diseases, Department of General Medicine; Unit of Microbiology, Department of Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Zorzi
authors.affiliation: Unit of Infectious Diseases, Department of General Medicine; Unit of Microbiology, Department of Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Rigo
authors.affiliation: Unit of Infectious Diseases, Department of General Medicine; Unit of Microbiology, Department of Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
authors.forename: Irene
authors.initials: I
authors.lastname: Adami
authors.affiliation: Unit of Infectious Diseases, Department of General Medicine; Unit of Microbiology, Department of Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Del Bravo
authors.affiliation: Unit of Infectious Diseases, Department of General Medicine; Unit of Microbiology, Department of Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Tonolli
authors.affiliation: Unit of Infectious Diseases, Department of General Medicine; Unit of Microbiology, Department of Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
authors.forename: Ercole
authors.initials: E
authors.lastname: Concia
authors.affiliation: Unit of Infectious Diseases, Department of General Medicine; Unit of Microbiology, Department of Pathology and Diagnostics, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Azzini
mesh_terms: D000328:Adult; D015483:HIV Antibodies / Q000097:blood*; D015488:HIV Antigens / Q000097:blood*; D015658:HIV Infections / Q000175:diagnosis* / Q000276:immunology / Q000821:virology; D015497:HIV-1 / Q000276:immunology / Q000302:isolation & purification*; D015498:HIV-2 / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007118:Immunoassay / Q000379:methods; D008297:Male; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
chemical_list: D015483:HIV Antibodies; D015488:HIV Antigens