title: The COMET Sleep Research Platform.
abstract: BACKGROUND
  The Comparative Outcomes Management with Electronic Data Technology (COMET) platform is extensible and designed for facilitating multicenter electronic clinical research.
  
  
  BACKGROUND
  Our research goals were the following: (1) to conduct a comparative effectiveness trial (CET) for two obstructive sleep apnea treatments-positive airway pressure versus oral appliance therapy; and (2) to establish a new electronic network infrastructure that would support this study and other clinical research studies.
  
  
  CONCLUSIONS
  The COMET platform was created to satisfy the needs of CET with a focus on creating a platform that provides comprehensive toolsets, multisite collaboration, and end-to-end data management. The platform also provides medical researchers the ability to visualize and interpret data using business intelligence (BI) tools.
  
  
  CONCLUSIONS
  COMET is a research platform that is scalable and extensible, and which, in a future version, can accommodate big data sets and enable efficient and effective research across multiple studies and medical specialties. The COMET platform components were designed for an eventual move to a cloud computing infrastructure that enhances sustainability, overall cost effectiveness, and return on investment.
authors.affiliation: Stanford Sleep Medicine Center.
authors.forename: Deborah A
authors.initials: DA
authors.lastname: Nichols
authors.affiliation: Stanford Sleep Medicine Center.
authors.forename: Steven
authors.initials: S
authors.lastname: DeSalvo
authors.affiliation: Stanford Sleep Medicine Center.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Miller
authors.affiliation: Stanford Sleep Medicine Center.
authors.forename: Darrell
authors.initials: D
authors.lastname: Jónsson
authors.affiliation: St. Luke's Hospital.
authors.forename: Kara S
authors.initials: KS
authors.lastname: Griffin
authors.affiliation: Stanford Sleep Medicine Center.
authors.forename: Pamela R
authors.initials: PR
authors.lastname: Hyde
authors.affiliation: St. Luke's Hospital.
authors.forename: James K
authors.initials: JK
authors.lastname: Walsh
authors.affiliation: Stanford Sleep Medicine Center.
authors.forename: Clete A
authors.initials: CA
authors.lastname: Kushida
keywords: COMET; business intelligence; cloud computing; comparative effectiveness research; obstructive sleep apnea; research platform
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