title: Make them, break them, and catch them: studying rare ubiquitin chains.
abstract: Two studies in this issue, Kristariyanto et al. (2015) and Michel et al. (2015), describe innovative ways to produce large quantities of atypical K29 and K33 ubiquitin chains and report structures and mechanisms of chain-specific recognition.
authors.affiliation: Division of Biochemistry and CGC.nl, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands.
authors.forename: Michael
authors.initials: M
authors.lastname: Uckelmann
authors.affiliation: Division of Biochemistry and CGC.nl, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, the Netherlands. Electronic address: t.sixma@nki.nl.
authors.forename: Titia K
authors.initials: TK
authors.lastname: Sixma
mesh_terms: D010450:Endopeptidases / Q000737:chemistry*; D006801:Humans; D008239:Lysine / Q000737:chemistry*; D011499:Protein Processing, Post-Translational; D025801:Ubiquitin / Q000737:chemistry*; D044767:Ubiquitin-Protein Ligases / Q000737:chemistry*
chemical_list: D025801:Ubiquitin; C555759:UBE3C protein, human; D044767:Ubiquitin-Protein Ligases; D010450:Endopeptidases; C570449:ZRANB1 protein, human; D008239:Lysine