title: Clinical analysis of 1629 newly diagnosed malignant lymphomas in current residents of Sichuan province, China.
abstract: Previous studies in other provinces of China (Beijing, Xinjiang, Shanxi, Jiangxi, Shanghai, Guangdong, and Taiwan) suggest that the distributions of lymphoma subtypes differ compared with Western populations. In order to evaluate the characteristics of malignant lymphoma in Sichuan, China, we analyzed case series data from incident lymphoma patients diagnosed in 2008 from three hospitals, including a total of 1629 cases and including only current residents of Sichuan. The median age of diagnosis for cases was 54 years, with a higher proportion of male cases compared with female cases. The most commonly diagnosed subtypes included diffuse large B-cell lymphoma (40.4%), NK/T-cell lymphoma (NKTCL; 11.8%), mixed cellularity Hodgkin lymphoma (7.0%), mantle cell lymphoma (4.8%), and marginal zone B-cell lymphoma (3.9%). Differences in demographic characteristics between Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) cases were apparent for median age at diagnosis (HL: 34 years; NHL: 57 years), and NHLs accounted for nearly all (99.3%) of the 931 cases of extranodal lymphoma. These findings indicate a higher proportion of NKTCL cases and a lower proportion of follicular lymphoma cases (2.3%) in these hospitals in Sichuan, relative to reports from some other provinces within China (e.g., Shanghai and Shanxi) and the USA. Copyright © 2015 John Wiley & Sons, Ltd.
authors.affiliation: Department of Hematology, Hematology Research Laboratory and Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Wang
authors.affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA.
authors.forename: Bryan A
authors.initials: BA
authors.lastname: Bassig
authors.affiliation: Department of Hematology, Hematology Research Laboratory and Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Wen
authors.affiliation: Department of Hematology, Hematology Research Laboratory and Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
authors.forename: Gan-di
authors.initials: GD
authors.lastname: Li
authors.affiliation: Department of Hematology, Hematology Research Laboratory and Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
authors.forename: Zhi-Bin
authors.initials: ZB
authors.lastname: Liu
authors.affiliation: Department of Internal Medicine and Pathology, The Sichuan Province Tumour Hospital, Chengdu, Sichuan, China.
authors.forename: Wen-Xiu
authors.initials: WX
authors.lastname: Yao
authors.affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Hu
authors.affiliation: Department of Internal Medicine and Pathology, The Sichuan Province Tumour Hospital, Chengdu, Sichuan, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Internal Medicine and Pathology, The Sichuan Province Tumour Hospital, Chengdu, Sichuan, China.
authors.forename: Ji-Man
authors.initials: JM
authors.lastname: Li
authors.affiliation: Department of Hematology and Pathology, The Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
authors.forename: Xiao-Dong
authors.initials: XD
authors.lastname: Wang
authors.affiliation: Department of Hematology and Pathology, The Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
authors.forename: Mao-Zhou
authors.initials: MZ
authors.lastname: Gan
authors.affiliation: Department of Hematology and Pathology, The Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
authors.forename: Chun-Sen
authors.initials: CS
authors.lastname: Wang
authors.affiliation: Department of Hematology and Pathology, The Sichuan Provincial People's Hospital, Chengdu, Sichuan, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Xu
authors.affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA.
authors.forename: Nathaniel
authors.initials: N
authors.lastname: Rothman
authors.affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA.
authors.forename: Qing
authors.initials: Q
authors.lastname: Lan
authors.affiliation: Department of Hematology, Hematology Research Laboratory and Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
authors.forename: Cai-Gang
authors.initials: CG
authors.lastname: Xu
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008223:Lymphoma / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged
keywords: China; descriptive epidemiology; geographical variation; lymphoma
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