title: Oral health-related quality of life before hematopoietic stem cell transplantation.
abstract: OBJECTIVE
  This study was planned to evaluate the impact of oral health on the quality of life (QoL) of patients undergoing hematopoietic stem cell transplantation (HSCT).
  
  
  METHODS
  We assessed 200 patients divided into two paired groups: 100 patients prior to HSCT (SG) and 100 healthy volunteers (CG). We applied the Oral Health Impact Profile instrument, which is based on the biopsychosocial problem gradation of World Health Organization (WHO) and relates oral health problems with QoL according to seven dimensions.
  
  
  RESULTS
  Fourteen patients in SG were referred for extraction of one to eight teeth, mostly due to deep caries with risk of pulpal infection and possible spread of infection via blood (r = 0.59, p = 0.000). The presence of severely compromised teeth by extensive decay correlated with Oral Health Impact Profile (OHIP-14). The Mann-Whitney test showed a significant difference between SG and CG in the following dimensions: functional limitation (p < 0.001), physical pain (p = 0.025), physical disability (p = 0.016), and social disability (p = 0.01).
  
  
  CONCLUSIONS
  The impact of oral health on QoL of onco-hematologic patients is weak but is greater as compared to healthy ones. Nevertheless, a significant impact is seen in patients with severely compromised teeth.
  
  
  CONCLUSIONS
  The negligence of oral care, proper hygiene, and the search for dental care may increase the risk for local and systemic infections.
authors.affiliation: Potiguar University, Laureate International Universities, Av. Sen Salgado Filho, 1610, Natal, 59056-000, Brazil. tinocoaraujo@gmail.com.
authors.forename: J E
authors.initials: JE
authors.lastname: Tinoco-Araujo
authors.affiliation: Raul Bauab Educational Foundation, Jau, Brazil.
authors.forename: E S L
authors.initials: ES
authors.lastname: Orti-Raduan
authors.affiliation: Stomatology Department, Bauru School of Dentistry, University of Sao Paulo, Bauru, Brazil.
authors.forename: D
authors.initials: D
authors.lastname: Santos
authors.affiliation: BMT Unit, Amaral Carvalho Hospital Foundation, Jau, Brazil.
authors.forename: V A R
authors.initials: VA
authors.lastname: Colturato
authors.affiliation: BMT Unit, Amaral Carvalho Hospital Foundation, Jau, Brazil.
authors.forename: M P
authors.initials: MP
authors.lastname: Souza
authors.affiliation: BMT Unit, Amaral Carvalho Hospital Foundation, Jau, Brazil.
authors.forename: M A
authors.initials: MA
authors.lastname: Mauad
authors.affiliation: BMT Unit, Amaral Carvalho Hospital Foundation, Jau, Brazil.
authors.forename: T C M
authors.initials: TC
authors.lastname: Saggioro
authors.affiliation: Department of Paedodontics, Orthodontics and Public Health of Dentistry, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
authors.forename: R S
authors.initials: RS
authors.lastname: Bastos
authors.affiliation: Stomatology Department, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.
authors.forename: P S
authors.initials: PS
authors.lastname: da Silva Santos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009909:Oral Health; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014076:Tooth Diseases / Q000453:epidemiology
keywords: Hematopoietic stem cell transplantation; Oral health; Quality of life; Sickness impact profile
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