title: Dengue seroprevalence in the French West Indies: a prospective study in adult blood donors.
abstract: Using an anti-dengue immunoglobulin G (IgG) indirect enzyme-linked immunosorbent assay, seroprevalence was determined among 783 adult blood donors in the French Caribbean islands of Guadeloupe and Martinique in 2011. Overall, 93.5% [91.5; 95.1] samples were positive for dengue antibodies, 90.7% (350 of 386) in Martinique and 96.2% (382 of 397) in Guadeloupe. Only 30% of these adults recalled having had dengue disease before. Serotype-specific neutralization assays applied to a subset of IgG-positive samples indicated that a majority (77 of 96; 80%) reacted to the four serotypes. These seroprevalence findings are the first reported for Guadeloupe and Martinique and are consistent with the dengue epidemiology in these territories.
authors.forename: Maïna
authors.initials: M
authors.lastname: L'Azou
authors.forename: Janick
authors.initials: J
authors.lastname: Jean-Marie
authors.forename: Maël
authors.initials: M
authors.lastname: Bessaud
authors.forename: André
authors.initials: A
authors.lastname: Cabié
authors.forename: Raymond
authors.initials: R
authors.lastname: Césaire
authors.forename: Xavier
authors.initials: X
authors.lastname: de Lamballerie
authors.forename: Rémi
authors.initials: R
authors.lastname: Courbil
authors.forename: Pascale
authors.initials: P
authors.lastname: Richard
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000914:Antibodies, Viral / Q000276:immunology; D001782:Blood Donors / Q000706:statistics & numerical data*; D003715:Dengue / Q000453:epidemiology*; D003716:Dengue Virus / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D019430:Guadeloupe / Q000453:epidemiology; D006801:Humans; D008297:Male; D008395:Martinique / Q000453:epidemiology; D008875:Middle Aged; D011446:Prospective Studies; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral
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