title: Influenza virus infections in the tropics during the first year of life.
abstract: Pediatric influenza virus infections in the tropics, particularly during infancy, are not well described. We identified influenza virus infections among infants with non-dengue acute undifferentiated febrile illnesses in San Pablo, Laguna, Philippines, as part of an ongoing clinical study of dengue virus infections during infancy. We found that 31% of infants with non-dengue acute undifferentiated febrile illnesses in San Pablo, Laguna, Philippines, had influenza virus infections. The majority were influenza A virus infections and outpatient cases. The infant ages were 11.1 [9.8-13.0] months (median [95% confidence interval]), and the cases clustered between June and December. Influenza episodes are a common cause of non-dengue acute undifferentiated febrile illnesses in the tropics during the first year of life.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, University of Massachusetts Medical School, Worcester, USA 01655 daniel.libraty@umassmed.edu.
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Libraty
authors.affiliation: Division of Infectious Diseases, Department of Medicine, University of Massachusetts Medical School, Worcester, USA 01655.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.affiliation: San Pablo City Health Office, San Pablo, Laguna, Philippines 1770.
authors.forename: Mercydina
authors.initials: M
authors.lastname: Caponpon
authors.affiliation: Departments of Medicine and Microbiology, Research Institute for Tropical Medicine, Metro Manila, Philippines 1770.
authors.forename: Rosario Z
authors.initials: RZ
authors.lastname: Capeding
mesh_terms: D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005334:Fever / Q000097:blood / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D029524:Betainfluenzavirus / Q000302:isolation & purification*; D008297:Male; D010679:Philippines / Q000453:epidemiology
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M
references.citation: PLoS Med. 2009 Oct;6(10):e1000171
references.pmid: 19859541
references.citation: Pediatr Infect Dis J. 2010 Mar;29(3):216-21
references.pmid: 20190613