title: [Interstitial endocrine apparatus of testes of experimental animals in conditions of chromium-benzene intoxication].
abstract: With the use of histological, morphometric and statistical methods there was shown a gonadotropic effect of chromium, benzene and also their mixtures in male mice (CBA x C57Bl6) F1. The established structural changes in the testes of exposed animals showed the suppression of their germinative and endocrine functions. The response of Leydig cells in the chromium group expresses a development of the compensatory process in the relation with the destruction of seminiferous epithelium.
authors.forename: D A
authors.initials: DA
authors.lastname: Bokov
authors.forename: E V
authors.initials: EV
authors.lastname: Ermolina
authors.forename: M V
authors.initials: MV
authors.lastname: Semenova
authors.forename: A I
authors.initials: AI
authors.lastname: Smoyiagin
authors.forename: A A
authors.initials: AA
authors.lastname: Stadnikov
mesh_terms: D000818:Animals; D001554:Benzene / Q000493:pharmacokinetics / Q000633:toxicity; D002857:Chromium / Q000493:pharmacokinetics / Q000633:toxicity; D007985:Leydig Cells / Q000187:drug effects / Q000473:pathology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D023421:Models, Animal; D013091:Spermatogenesis / Q000187:drug effects*; D013092:Spermatogenesis-Blocking Agents / Q000493:pharmacokinetics / Q000633:toxicity; D066007:Toxicokinetics
chemical_list: D013092:Spermatogenesis-Blocking Agents; D002857:Chromium; D001554:Benzene