title: Pancreatic cystic neoplasms: Review of current knowledge, diagnostic challenges, and management options.
abstract: Pancreatic cystic lesions are being detected with increasing frequency, largely due to advances in cross-sectional imaging. The most common neoplasms include serous cystadenomas, mucinous cystic neoplasms, intraductal papillary mucinous neoplasms, solid pseudopapillary neoplasms, and cystic pancreatic endocrine neoplasms. Computed tomography (CT), magnetic resonance imaging (MRI), and endoscopic ultrasound (EUS) are currently used as imaging modalities. EUS-guided fine needle aspiration has proved to be a useful diagnostic tool, and enables an assessment of tumor markers, cytology, chemistries, and DNA analysis. Here, we review the current literature on pancreatic cystic neoplasms, including classification, diagnosis, treatment, and recommendations for surveillance. Data for this manuscript was acquired via searching the literature from inception to December 2014 on PubMed and Ovid MEDLINE.
authors.affiliation: Department of Internal Medicine, University of Texas Medical School at Houston, Houston, TX, USA.
authors.forename: Tanima
authors.initials: T
authors.lastname: Jana
authors.affiliation: Department of Internal Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Texas Medical School at Houston, Houston, TX, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Shroff
authors.affiliation: Department of Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
authors.forename: Manoop S
authors.initials: MS
authors.lastname: Bhutani
keywords: Cystic pancreatic endocrine neoplasm; endoscopic ultrasound; endosonography; intraductal papillary mucinous neoplasm; mucinous cystic neoplasm; pancreatic cystic neoplasms; serous cystic neoplasm; solid pseudopapillary neoplasm
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