title: Designing a new model for cosmetic adverse reaction monitoring in China.
abstract: BACKGROUND
  The monitoring of cosmetic adverse reactions (CARs) in China has progressed to a new stage of development because of government institutional reforms.
  
  
  OBJECTIVE
  To discuss and formulate an appropriate model for CAR monitoring in China.
  
  
  METHODS
  The formulation of a new CAR-monitoring model under the administration of the Food and Drug Supervision Department is discussed on the basis of China's current national conditions and with reference to the previous CAR-monitoring and drug-monitoring models of the organization formerly known as the Ministry of Health of the People's Republic of China.
  
  
  RESULTS
  The preliminary design of the CAR-monitoring model is considered to be a long-term development goal of CAR monitoring. The monitoring model at this stage was developed on the basis of China's national conditions; specifically, the development of a two-level (national and provincial agencies) monitoring system that relies on CAR-monitoring sentinels, and reports that cover CARs with definite causal associations.
  
  
  CONCLUSIONS
  This model is developed on both theoretical and practical foundations, and can function as a proper monitoring model at the initial stage of current CAR monitoring through an appropriate pilot programme, exploration, and improvement.
authors.affiliation: Shandong Provincial Centre for Adverse Drug Reaction Monitoring, Ji'nan, Shandong 250013, China.
authors.forename: Changfei
authors.initials: C
authors.lastname: Lu
authors.affiliation: National Centre for Adverse Drug Reaction Monitoring, Beijing 100045, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Cheng
authors.affiliation: National Centre for Adverse Drug Reaction Monitoring, Beijing 100045, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Shen
authors.affiliation: Shandong Provincial Centre for Adverse Drug Reaction Monitoring, Ji'nan, Shandong 250013, China.
authors.forename: Yuejie
authors.initials: Y
authors.lastname: Tian
authors.affiliation: Shandong Provincial Centre for Adverse Drug Reaction Monitoring, Ji'nan, Shandong 250013, China.
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Zhou
authors.affiliation: National Centre for Adverse Drug Reaction Monitoring, Beijing 100045, China.
authors.forename: Xinlin
authors.initials: X
authors.lastname: Li
authors.affiliation: National Centre for Adverse Drug Reaction Monitoring, Beijing 100045, China.
authors.forename: Xiaoxi
authors.initials: X
authors.lastname: Du
mesh_terms: D002681:China / Q000453:epidemiology; D003358:Cosmetics / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D011358:Product Surveillance, Postmarketing / Q000379:methods*
chemical_list: D003358:Cosmetics
keywords: cosmetic adverse reactions (CARs); design; model; monitoring