title: [Age-related changes in swallowing. Physiology and pathophysiology].
abstract: The term presbyphagia refers to all changes of swallowing physiology that are manifested with increasing age. Alterations in the pattern of deglutition that are part of healthy aging are called primary presbyphagia. Primary presbyphagia is not an illness in itself but contributes to a more pervasive naturally diminished functional reserve, making older adults more susceptible to dysphagia. If disorders in swallowing occur in the elderly as a comorbidity of a specific disease, for example stroke or neurodegenerative disorders, this is called secondary presbyphagia. Increasing age has an impact on each stage of deglutition. In the oral preparatory phase a diminished input for smell and taste as well as a usually multifactorial cause of dry mouth are the most important influencing factors. Sarcopenia, the degenerative loss of skeletal muscle mass, strength and quality associated with aging, interferes in particular with the oropharyngeal phase. A decreased sensory feedback from the oropharyngeal mucosa leads to a delayed triggering of the swallowing reflex. Finally, a reduction in connective tissue elasticity and changes of the axial skeleton lead to various modifications of the swallowing pattern with advanced age.
authors.affiliation: Klinik für Allgemeine Neurologie, Universitätsklinikum Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Deutschland, Paul.Muhle@ukmuenster.de.
authors.forename: P
authors.initials: P
authors.lastname: Muhle
authors.forename: R
authors.initials: R
authors.lastname: Wirth
authors.forename: J
authors.initials: J
authors.lastname: Glahn
authors.forename: R
authors.initials: R
authors.lastname: Dziewas
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D003679:Deglutition; D003680:Deglutition Disorders / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology*; D003937:Diagnosis, Differential; D005260:Female; D015577:Geriatric Assessment / Q000379:methods; D006801:Humans; D008297:Male; D019636:Neurodegenerative Diseases / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*; D055948:Sarcopenia / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology
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