title: Frequency of adenoviruses, rotaviruses and noroviruses among diarrhea samples collected from infants of zabol, southeastern iran.
abstract: BACKGROUND
  Viruses are one of the major reasons of gastrointestinal disease worldwide, and commonly infect children less than five years of age in developing countries.
  
  
  OBJECTIVE
  The current study aimed to determine the frequency of adenoviruses, rotaviruses and noroviruses among diarrhea samples collected from infants of Zabol, south-east of Iran. This study is the first investigation of adenoviruses, rotaviruses and noroviruses among diarrhea samples in Zabol.
  
  
  METHODS
  In this study, eighty-two diarrhea stool samples were collected from infants aged < 1 to 12 months admitted to the hospital, internal laboratory and central laboratory of Zabol, Iran. All samples were subjected to the rapid immunochromatography assay.
  
  
  RESULTS
  The results showed that the frequency of rotaviruses, adenoviruses and noroviruses among infants with diarrhea were 70.20%, 20.30% and 9.50%, respectively. There were 50 subjects aged one to five months and 2 subjects aged nine to twelve months. The results of geographical distribution showed that the number of infants living in rural and urban areas with these viruses were 50 and 32, respectively. Rotaviruses were most common in rural and urban infants with 42 and 10 cases, respectively. Regarding the feeding patterns of infants with diarrhea, mixed feeding and breast feeding were found in 51 and 31 cases, respectively.
  
  
  CONCLUSIONS
  In conclusion, the results of our study showed that the major viral pathogens that caused infantile diarrhea in Zabol city were rotaviruses followed by adenoviruses and noroviruses. The results of our study can useful for prosperous control of infantile diarrhea.
authors.affiliation: Zabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol, IR Iran ; Department of Pharmacognosy, Faculty of Pharmacy, Zabol University of Medical Sciences, Zabol, IR Iran.
authors.forename: Javad
authors.initials: J
authors.lastname: Sharifi-Rad
authors.affiliation: Pediatric Infections Research Center, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
authors.forename: Seyedeh Mahsan
authors.initials: SM
authors.lastname: Hoseini Alfatemi
authors.affiliation: Zabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol, IR Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Sharifi-Rad
authors.affiliation: Zabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol, IR Iran ; Department of Pharmacognosy, Faculty of Pharmacy, Zabol University of Medical Sciences, Zabol, IR Iran.
authors.forename: Abdolhossein
authors.initials: A
authors.lastname: Miri
keywords: Adenoviruses; Infantile Diarrhea; Noroviruses; Rotavirus
references.citation: Acta Med Iran. 2010 Jul-Aug;48(4):263-5
references.pmid: 21279942
references.citation: Pediatrics. 2004 Jan;113(1 Pt 1):e51-6
references.pmid: 14702495
references.citation: BMC Public Health. 2007 Dec 27;7:359
references.pmid: 18162127
references.citation: J Clin Microbiol. 2002 Dec;40(12):4797-9
references.pmid: 12454200
references.citation: Emerg Infect Dis. 1998 Oct-Dec;4(4):561-70
references.pmid: 9866732
references.citation: Curr Opin Gastroenterol. 2007 Jan;23(1):39-43
references.pmid: 17133083
references.citation: Korean J Lab Med. 2007 Dec;27(6):437-41
references.pmid: 18160834
references.citation: Virol J. 2005 Feb 10;2:6
references.pmid: 15705203
references.citation: J Med Virol. 2010 Apr;82(4):632-7
references.pmid: 20166189
references.citation: Curr Opin Gastroenterol. 2005 Jan;21(1):26-31
references.pmid: 15687881
references.citation: Iran Red Crescent Med J. 2013 Aug;15(8):729-33
references.pmid: 24578843
references.citation: J Infect Dis. 2005 Sep 1;192(5):913-9
references.pmid: 16088842
references.citation: Pediatr Infect Dis J. 2009 Mar;28(3 Suppl):S50-3
references.pmid: 19252423
references.citation: J Clin Microbiol. 2010 May;48(5):1943-6
references.pmid: 20305010
references.citation: Lancet. 2006 Jul 22;368(9532):323-32
references.pmid: 16860702
references.citation: Virol J. 2012 Feb 23;9:54
references.pmid: 22361160
references.citation: BMC Infect Dis. 2013 May 08;13:209
references.pmid: 23657114
references.citation: Emerg Infect Dis. 2006 Feb;12(2):304-6
references.pmid: 16494759
references.citation: Bull World Health Organ. 2003;81(3):197-204
references.pmid: 12764516
references.citation: J Med Virol. 2013 Aug;85(8):1485-90
references.pmid: 23765785
references.citation: J Infect Dis. 2001 Jun 15;183(12):1707-12
references.pmid: 11372022
references.citation: J Clin Microbiol. 2007 Aug;45(8):2695-7
references.pmid: 17596373
references.citation: Virol J. 2013 Oct 08;10:302
references.pmid: 24099150
references.citation: Nat Clin Pract Gastroenterol Hepatol. 2008 Nov;5(11):637-47
references.pmid: 18813221