title: Factors associated with the quality of life of Korean COPD patients as measured by the EQ-5D.
abstract: OBJECTIVE
  This study evaluated the health-related quality of life measured using the EuroQol five-dimension questionnaire (EQ-5D) and the degree of airway obstruction in a Korean population using Korea National Health and Nutritional Examination Survey (KNHANES IV-V, 2007-2010) data.
  
  
  METHODS
  A cross-sectional analysis examined 2356 subjects (1178 COPD patients, 1178 control subjects) aged ≥40 years and performed reliable spirometry as part of KNHANES IV-V. Baseline EQ-5D visual analog scale (VAS) and EQ-5D utility scores were obtained. A Tobit censored regression model was used to evaluate factors affecting EQ-5D in COPD patients.
  
  
  RESULTS
  The EQ-5D VAS and EQ-5D utility scores were significantly different among the COPD severity groups (P < 0.05). The mean EQ-5D VAS scores for patients with mild, moderate, and severe COPD were 73.0 (SD 18.6), 70.8 (19.1), and 60.9 (23.4), respectively. The mean utility scores were 0.90 (0.14) for patients with mild COPD, 0.89 (0.14) for patients with moderate COPD, and 0.84 (0.15) for patients with severe COPD. Factors influencing the EQ-5D utility score in patients with COPD were age, gender, household income, education level, severe airflow obstruction, and comorbidities.
  
  
  CONCLUSIONS
  The EQ-5D score could be a useful instrument for evaluating the quality of life of COPD patients in Korea. In Korean COPD patients, the main determinants of EQ-5D scores include older age, female gender, lower household income, lower education level, severe airflow obstruction, and many comorbid diseases.
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Hong
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
authors.forename: Song Yee
authors.initials: SY
authors.lastname: Kim
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
authors.forename: Kyung Soo
authors.initials: KS
authors.lastname: Chung
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Kim
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
authors.forename: Ji Ye
authors.initials: JY
authors.lastname: Jung
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
authors.forename: Moo Suk
authors.initials: MS
authors.lastname: Park
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
authors.forename: Young Ae
authors.initials: YA
authors.lastname: Kang
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
authors.forename: Se Kyu
authors.initials: SK
authors.lastname: Kim
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
authors.forename: Joon
authors.initials: J
authors.lastname: Chang
authors.affiliation: Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul, 120-752, Republic of Korea. ysamkim@yuhs.ac.
authors.forename: Young Sam
authors.initials: YS
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000453:epidemiology*; D011788:Quality of Life; D056910:Republic of Korea; D011795:Surveys and Questionnaires
keywords: Chronic obstructive lung disease; Health surveys; Korea; Quality of life; Spirometry
references.citation: Ann Med. 2001 Jul;33(5):337-43
references.pmid: 11491192
references.citation: Ann Intern Med. 1993 Apr 15;118(8):622-9
references.pmid: 8452328
references.citation: Respir Res. 2009 Jun 30;10:59
references.pmid: 19566934
references.citation: Health Policy. 1996 Jul;37(1):53-72
references.pmid: 10158943
references.citation: Health Qual Life Outcomes. 2007 Apr 27;5:21
references.pmid: 17462100
references.citation: Respir Med. 2007 Mar;101(3):661-9
references.pmid: 17197164
references.citation: COPD. 2009 Feb;6(1):59-63
references.pmid: 19229709
references.citation: Lancet. 2009 Oct 3;374(9696):1171-8
references.pmid: 19716598
references.citation: Respir Med. 2012 Mar;106(3):367-73
references.pmid: 22018505
references.citation: Eur Respir J. 2011 Apr;37(4):738-42
references.pmid: 21454890
references.citation: COPD. 2012 Feb;9(1):46-57
references.pmid: 22292597
references.citation: Thorax. 1996 Jan;51(1):39-43
references.pmid: 8658367
references.citation: Health Qual Life Outcomes. 2006 May 23;4:31
references.pmid: 16719899
references.citation: Respir Med. 2013 Feb;107(2):233-41
references.pmid: 23098687
references.citation: Eur Respir J. 2010 Sep;36(3):480-7
references.pmid: 20150201
references.citation: Health Policy. 1990 Dec;16(3):199-208
references.pmid: 10109801
references.citation: Health Qual Life Outcomes. 2013 Nov 05;11:190
references.pmid: 24192270
references.citation: Chest. 2006 Oct;130(4):1117-28
references.pmid: 17035446
references.citation: J Rural Health. 2013 Aug;29 Suppl 1:s62-9
references.pmid: 23944281
references.citation: Health Qual Life Outcomes. 2005 Sep 09;3:56
references.pmid: 16153294
references.citation: Am J Respir Crit Care Med. 2013 Feb 15;187(4):347-65
references.pmid: 22878278
references.citation: Age Ageing. 2006 Jan;35(1):33-7
references.pmid: 16364931
references.citation: BMC Pulm Med. 2009 Jan 02;9:2
references.pmid: 19121205
references.citation: Health Qual Life Outcomes. 2011 Apr 18;9:26
references.pmid: 21501522
references.citation: Eur Respir J. 2003 Sep;22(3):444-9
references.pmid: 14516133
references.citation: Respirology. 2011 May;16(4):659-65
references.pmid: 21342331
references.citation: Am J Respir Crit Care Med. 2007 Sep 15;176(6):532-55
references.pmid: 17507545
references.citation: Respiration. 2011;82(5):402-8
references.pmid: 21778694
references.citation: Health Qual Life Outcomes. 2012 Aug 21;10:98
references.pmid: 22909154
references.citation: J Med Life. 2014 Mar 15;7(1):100-3
references.pmid: 24653767
references.citation: Chest. 1996 Oct;110(4):896-903
references.pmid: 8874242
references.citation: Value Health. 2009 Nov-Dec;12(8):1187-93
references.pmid: 19659703
references.citation: Health Qual Life Outcomes. 2014 Apr 24;12:57
references.pmid: 24758364
references.citation: Respir Med. 1991 Sep;85 Suppl B:25-31; discussion 33-7
references.pmid: 1759018
references.citation: Ann Intern Med. 1997 Dec 15;127(12):1072-9
references.pmid: 9412309