title: Synchronous primary lung cancer presenting with small cell carcinoma and adenocarcinoma.
abstract: Multiple synchronous primary lung cancers presenting with different histologic types are uncommon. Among reported cases with different histologic findings, only a few had small cell lung cancer (SCLC) and adenocarcinoma. This unusual combination of lung cancers has not been well reported. In this report, we describe two cases of synchronous primary lung cancer presenting with lymph node metastasis of SCLC and early-stage adenocarcinoma. Epidermal growth factor receptor (EGFR) mutation was not detected in either SCLC or adenocarcinoma in the two cases.
authors.affiliation: Department of Thoracic Surgery, Yao Municipal Hospital, Yao, Osaka, Japan.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Ken
authors.initials: K
authors.lastname: Kodama
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yamato
authors.forename: Masashi
authors.initials: M
authors.lastname: Takeda
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Takamori
authors.forename: Takahiro
authors.initials: T
authors.lastname: Karasuno
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D000077192:Adenocarcinoma of Lung; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D008207:Lymphatic Metastasis; D008297:Male; D064847:Multimodal Imaging; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000473:pathology* / Q000628:therapy; D011013:Pneumonectomy; D049268:Positron-Emission Tomography; D055752:Small Cell Lung Carcinoma / Q000737:chemistry / Q000556:secondary* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor
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