title: Repair of Tetralogy of Fallot in Children Less Than 4 kg Body Weight.
abstract: We reviewed our experience of surgical repair of Tetralogy of Fallot (TOF) in children weighing less than or equal to 4 kg to compare outcome of early palliation versus complete repair as the initial surgical approach. Seventy-six patients, weighing ≤ 4 kg, with TOF surgery between January 2005 and September 2013 were included in this single-center retrospective study. Twenty-five patients who underwent initial shunt procedure followed by later full repair were compared to 51 patients who had primary full repair for differences in baseline characteristics and outcomes. Shunt group patients had lower body weight, 2.76 ± 0.69 versus 3.11 ± 0.65 (kg), p = 0.03, and lower preoperative oxygen saturations, 82 ± 7 versus 90 ± 6 (%), p = 0.0001, than full repair group. A higher number of surgical procedures per patient was recorded in shunt patients, 2.29 ± 0.59 versus 1.27 ± 0.49, p = 0.00002. Thirteen of 51 patients in the full repair group required a repeat surgery. Catheterization procedures were performed in 12 patients in shunt and in 15 patients in full repair group, with interventional angioplasty in three and 11, respectively, p ≥ 0.05. Two patients, both in the shunt group, died after the surgery. Early full repair had longer hospital stay but significantly less hospitalizations 1.95 ± 1.3 versus 2.5 ± 1.4, p = 0.03. Initial complete repair of TOF in small children yielded favorable outcome with significantly less surgical procedures and subsequent hospitalizations. Cath laboratory re-interventions for residual defects were similar after both surgical approaches, and type of initial surgery does not predict freedom from re-intervention.
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, Columbia University College of Physicians and Surgeons, Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY, USA.
authors.forename: Rabin
authors.initials: R
authors.lastname: Gerrah
authors.affiliation: Division of Pediatric Cardiology, Department of Pediatrics, Columbia University College of Physicians and Surgeons, Morgan Stanley Children's Hospital of New York-Presbyterian, 3959 Broadway, 2 North, New York, NY, 10032, USA. met2148@cumc.columbia.edu.
authors.forename: Mariel E
authors.initials: ME
authors.lastname: Turner
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, Columbia University College of Physicians and Surgeons, Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY, USA.
authors.forename: Danielle
authors.initials: D
authors.lastname: Gottlieb
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, Columbia University College of Physicians and Surgeons, Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY, USA.
authors.forename: Jan M
authors.initials: JM
authors.lastname: Quaegebeur
authors.affiliation: Division of Cardiothoracic Surgery, Department of Surgery, Columbia University College of Physicians and Surgeons, Morgan Stanley Children's Hospital of New York-Presbyterian, New York, NY, USA.
authors.forename: Emile
authors.initials: E
authors.lastname: Bacha
mesh_terms: D058366:Blalock-Taussig Procedure / Q000379:methods*; D001835:Body Weight / Q000502:physiology; D003490:Cyanosis / Q000209:etiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010166:Palliative Care; D012086:Reoperation / Q000379:methods*; D012189:Retrospective Studies; D013771:Tetralogy of Fallot / Q000601:surgery*; D014945:Wound Healing
keywords: Congenital; Cyanosis; Palliation; Shunt; Tetralogy of Fallot
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