title: Non-coding RNAs' partitioning in the evolution of photosynthetic organisms via energy transduction and redox signaling.
abstract: Ars longa, vita brevis -Hippocrates Chloroplasts and mitochondria are genetically semi-autonomous organelles inside the plant cell. These constructions formed after endosymbiosis and keep evolving throughout the history of life. Experimental evidence is provided for active non-coding RNAs (ncRNAs) in these prokaryote-like structures, and a possible functional imprinting on cellular electrophysiology by those RNA entities is described. Furthermore, updated knowledge on RNA metabolism of organellar genomes uncovers novel inter-communication bridges with the nucleus. This class of RNA molecules is considered as a unique ontogeny which transforms their biological role as a genetic rheostat into a synchronous biochemical one that can affect the energetic charge and redox homeostasis inside cells. A hypothesis is proposed where such modulation by non-coding RNAs is integrated with genetic signals regulating gene transfer. The implications of this working hypothesis are discussed, with particular reference to ncRNAs involvement in the organellar and nuclear genomes evolution since their integrity is functionally coupled with redox signals in photosynthetic organisms.
authors.affiliation: a Agro-environmental cooperative BioNet West Hellas ; Gastouni Ileias, Hellas , Greece.
authors.forename: Christos
authors.initials: C
authors.lastname: Kotakis
mesh_terms: D004734:Energy Metabolism; D019143:Evolution, Molecular; D010084:Oxidation-Reduction; D010788:Photosynthesis; D059828:Plant Cells / Q000145:classification* / Q000378:metabolism*; D022661:RNA, Untranslated / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D022661:RNA, Untranslated
keywords: RNA autonomy; cell bioenergetics; eco-evolution; endosymbiosis; organellar genome; plant physiology
references.citation: Genome Biol. 2011;12(1):215
references.pmid: 21235831
references.citation: Methods Mol Biol. 2004;257:223-44
references.pmid: 14770009
references.citation: Cold Spring Harb Symp Quant Biol. 2004;69:403-8
references.pmid: 16117674
references.citation: Mol Syst Biol. 2009;5:305
references.pmid: 19756044
references.citation: Biochim Biophys Acta. 2012 Aug;1817(8):1314-21
references.pmid: 22421105
references.citation: Adv Genet. 2002;46:235-75
references.pmid: 11931226
references.citation: Antioxid Redox Signal. 2013 Jun 1;18(16):2087-90
references.pmid: 23442120
references.citation: Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):409-14
references.pmid: 21173264
references.citation: Cell. 1991 Aug 9;66(3):473-81
references.pmid: 1714355
references.citation: Philos Trans R Soc Lond B Biol Sci. 2003 Jan 29;358(1429):19-37; discussion 37-8
references.pmid: 12594916
references.citation: EMBO J. 1992 Nov;11(11):3815-20
references.pmid: 1382979
references.citation: FEBS Lett. 2013 Sep 17;587(18):3096-101
references.pmid: 23954624
references.citation: BMC Plant Biol. 2010;10:220
references.pmid: 20939918
references.citation: Mol Syst Biol. 2007;3:138
references.pmid: 17893699
references.citation: Curr Biol. 2013 Jan 7;23(1):R30-2
references.pmid: 23305669
references.citation: Plant Signal Behav. 2012 Jul;7(7):882-4
references.pmid: 22751312
references.citation: Biochemistry (Mosc). 2012 Feb;77(2):143-51
references.pmid: 22348473
references.citation: Silence. 2011 Oct 26;2:8
references.pmid: 22029761
references.citation: J Theor Biol. 1993 Dec 21;165(4):609-31
references.pmid: 8114509
references.citation: Curr Biol. 2012 May 8;22(9):R296-8
references.pmid: 22575464
references.citation: Cell Biochem Funct. 2010 Oct;28(7):529-38
references.pmid: 20941743
references.citation: J Theor Biol. 2012 Oct 21;311:54-65
references.pmid: 22820491
references.citation: J Cell Biochem. 2013 Feb;114(2):418-27
references.pmid: 22961661
references.citation: Proc Natl Acad Sci U S A. 2012 Feb 14;109(7):2444-8
references.pmid: 22308419
references.citation: RNA Biol. 2013 Mar;10(3):453-5
references.pmid: 23324611
references.citation: Photosynth Res. 2011 Feb;107(2):169-75
references.pmid: 21302030
references.citation: Trends Plant Sci. 2012 Dec;17(12):737-44
references.pmid: 22981395
references.citation: Nat Rev Genet. 2004 Feb;5(2):123-35
references.pmid: 14735123
references.citation: J Theor Biol. 1967 Mar;14(3):255-74
references.pmid: 11541392
references.citation: Theory Biosci. 2005 Apr;123(4):301-69
references.pmid: 18202870
references.citation: Curr Biol. 2012 May 8;22(9):763-71
references.pmid: 22503505
references.citation: J Theor Biol. 2012 Mar 7;296:84-94
references.pmid: 22142622
references.citation: Environ Microbiol. 2007 Jan;9(1):39-45
references.pmid: 17227410
references.citation: PLoS Genet. 2010 Feb;6(2):e1000834
references.pmid: 20168995
references.citation: Nature. 2010 Oct 21;467(7318):929-34
references.pmid: 20962839
references.citation: PLoS One. 2010;5(8):e12269
references.pmid: 20808865
references.citation: Plant Physiol. 2005 Jul;138(3):1723-33
references.pmid: 15951485
references.citation: Nucleic Acids Res. 2006;34(14):3842-52
references.pmid: 16899451
references.citation: FEBS Lett. 1995 Oct 30;374(2):152-6
references.pmid: 7589523