title: Performance of a new carbon dioxide absorbent, Yabashi lime® as compared to conventional carbon dioxide absorbent during sevoflurane anesthesia in dogs.
abstract: In the present study, we compare a new carbon dioxide (CO2) absorbent, Yabashi lime(®) with a conventional CO2 absorbent, Sodasorb(®) as a control CO2 absorbent for Compound A (CA) and Carbon monoxide (CO) productions. Four dogs were anesthetized with sevoflurane. Each dog was anesthetized with four preparations, Yabashi lime(®) with high or low-flow rate of oxygen and control CO2 absorbent with high or low-flow rate. CA and CO concentrations in the anesthetic circuit, canister temperature and carbooxyhemoglobin (COHb) concentration in the blood were measured. Yabashi lime(®) did not produce CA. Control CO2 absorbent generated CA, and its concentration was significantly higher in low-flow rate than a high-flow rate. CO was generated only in low-flow rate groups, but there was no significance between Yabashi lime(®) groups and control CO2 absorbent groups. However, the CO concentration in the circuit could not be detected (≤5ppm), and no change was found in COHb level. Canister temperature was significantly higher in low-flow rate groups than high-flow rate groups. Furthermore, in low-flow rate groups, the lower layer of canister temperature in control CO2 absorbent group was significantly higher than Yabashi lime(®) group. CA and CO productions are thought to be related to the composition of CO2 absorbent, flow rate and canister temperature. Though CO concentration is equal, it might be safer to use Yabashi lime(®) with sevoflurane anesthesia in dogs than conventional CO2 absorbent at the point of CA production.
authors.affiliation: Laboratory of Veterinary Clinical Radiology, Faculty of Applied Biological Sciences, Gifu University, Gifu 501-1193, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Kondoh
authors.forename: Ayman
authors.initials: A
authors.lastname: Atiba
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Nagase
authors.forename: Shizuko
authors.initials: S
authors.lastname: Ogawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Miwa
authors.forename: Teruya
authors.initials: T
authors.lastname: Katsumata
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ueno
authors.forename: Yuji
authors.initials: Y
authors.lastname: Uzuka
mesh_terms: D000327:Adsorption; D000764:Anesthesia, Closed-Circuit / Q000295:instrumentation / Q000379:methods / Q000662:veterinary; D000769:Anesthesia, Inhalation / Q000379:methods / Q000662:veterinary*; D018685:Anesthetics, Inhalation; D000818:Animals; D002126:Calcium Hydroxide / Q000627:therapeutic use*; D002245:Carbon Dioxide / Q000097:blood; D002263:Carboxyhemoglobin / Q000032:analysis; D004285:Dogs / Q000601:surgery; D005260:Female; D008297:Male; D008738:Methyl Ethers; D010100:Oxygen / Q000097:blood; D000077149:Sevoflurane
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D002245:Carbon Dioxide; D000077149:Sevoflurane; D002263:Carboxyhemoglobin; D002126:Calcium Hydroxide; D010100:Oxygen
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