title: Carcinoma of the lungs causing enlarged kidneys.
abstract: Bilateral enlarged kidneys can be caused by a number of conditions. Renal metastasis is included in the differential diagnosis. We report a case of a 67-year-old woman with a 6-month history of productive cough and unintentional weight loss. Cavitary pulmonary lesions and bilateral enlarged kidneys were noted on imaging studies. Hematuria, azotemia, and proteinuria were present. Renal biopsy showed squamous carcinoma cells invading normal-appearing glomeruli and atrophic tubules. The invasive squamous cells stained negative for CK7 and CK 20. Lung biopsy confirmed squamous cell carcinoma. Our case shows that in patients with renal enlargement, even with the absence of a focal mass, renal metastasis should be considered, especially in those with suspected or diagnosed malignancy elsewhere.
authors.affiliation: Departments of Internal Medicine (Srisung, Mankongpaisarnrung, Sotello, Yarbrough, Laski) and Pathology (Warraich), Texas Tech University Health Sciences Center, Lubbock, Texas.
authors.forename: Weeraporn
authors.initials: W
authors.lastname: Srisung
authors.affiliation: Departments of Internal Medicine (Srisung, Mankongpaisarnrung, Sotello, Yarbrough, Laski) and Pathology (Warraich), Texas Tech University Health Sciences Center, Lubbock, Texas.
authors.forename: Charoen
authors.initials: C
authors.lastname: Mankongpaisarnrung
authors.affiliation: Departments of Internal Medicine (Srisung, Mankongpaisarnrung, Sotello, Yarbrough, Laski) and Pathology (Warraich), Texas Tech University Health Sciences Center, Lubbock, Texas.
authors.forename: Irfan
authors.initials: I
authors.lastname: Warraich
authors.affiliation: Departments of Internal Medicine (Srisung, Mankongpaisarnrung, Sotello, Yarbrough, Laski) and Pathology (Warraich), Texas Tech University Health Sciences Center, Lubbock, Texas.
authors.forename: David
authors.initials: D
authors.lastname: Sotello
authors.affiliation: Departments of Internal Medicine (Srisung, Mankongpaisarnrung, Sotello, Yarbrough, Laski) and Pathology (Warraich), Texas Tech University Health Sciences Center, Lubbock, Texas.
authors.forename: Shannon
authors.initials: S
authors.lastname: Yarbrough
authors.affiliation: Departments of Internal Medicine (Srisung, Mankongpaisarnrung, Sotello, Yarbrough, Laski) and Pathology (Warraich), Texas Tech University Health Sciences Center, Lubbock, Texas.
authors.forename: Melvin
authors.initials: M
authors.lastname: Laski
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