title: Yields and Utility of Endoscopic Ultrasonography-Guided 19-Gauge Trucut Biopsy versus 22-Gauge Fine Needle Aspiration for Diagnosing Gastric Subepithelial Tumors.
abstract: OBJECTIVE
  To evaluate the yields and utility of 19-gauge (G) Trucut biopsy (TCB) versus 22 G fine needle aspiration (FNA) for diagnosing gastric subepithelial tumors (SETs).
  
  
  METHODS
  We retrieved data for 152 patients with a gastric SET larger than 2 cm who had undergone endoscopic ultrasonography (EUS)-guided 19 G TCB (n=90) or 22 G FNA (n=62). Relevant clinical, tumor-specific, and EUS procedural information was reviewed retrospectively.
  
  
  RESULTS
  A specific diagnosis was made for 76 gastrointestinal stromal tumors (GISTs) and 51 non-GIST SETs. The diagnostic yield of TCB was greater than that of FNA (77.8% vs. 38.7%, p<0.001). The percentage of non-diagnostic specimens (suspicious and insufficient) was significantly lower in the TCB group (6.7% and 15.5%, respectively) than in the FNA group (22.6% and 38.7%, respectively; both p<0.001). TCB accurately diagnosed 90.9% of GISTs and 81.1% of non-GIST SETs, whereas FNA accurately diagnosed 68.8% of GISTs and 14.3% of non-GIST SETs. There were nine technical failures with TCB, and the rate of adverse events did not differ between the groups (TCB vs. FNA, 3.3% vs. 8.1%; p=0.27).
  
  
  CONCLUSIONS
  Nineteen-gauge TCB is safe and highly valuable for diagnosing gastric SETs larger than 2 cm if technical failure can be avoided.
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Hee Kyong
authors.initials: HK
authors.lastname: Na
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Jeong Hoon
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Young Soo
authors.initials: YS
authors.lastname: Park
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Ji Yong
authors.initials: JY
authors.lastname: Ahn
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Kwi-Sook
authors.initials: KS
authors.lastname: Choi
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Do Hoon
authors.initials: DH
authors.lastname: Kim
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Kee Don
authors.initials: KD
authors.lastname: Choi
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Ho June
authors.initials: HJ
authors.lastname: Song
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Gin Hyug
authors.initials: GH
authors.lastname: Lee
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Hwoon-Yong
authors.initials: HY
authors.lastname: Jung
authors.affiliation: Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Jin-Ho
authors.initials: JH
authors.lastname: Kim
keywords: Biopsy, large-core needle; Endoscopic ultrasound-guided fine needle aspiration; Endosonography; Stomach; Subepithelial tumors
references.citation: Clin Endosc. 2013 Sep;46(5):503-5
references.pmid: 24143312
references.citation: Am J Gastroenterol. 2009 Mar;104(3):584-91
references.pmid: 19262518
references.citation: World J Gastrointest Endosc. 2011 May 16;3(5):86-94
references.pmid: 21772939
references.citation: Clin Endosc. 2012 Jun;45(2):132-7
references.pmid: 22866253
references.citation: Gastrointest Endosc. 2011 Nov;74(5):1010-8
references.pmid: 21889136
references.citation: Curr Gastroenterol Rep. 2004 Apr;6(2):104-10
references.pmid: 15191687
references.citation: Endoscopy. 2005 Jul;37(7):630-4
references.pmid: 16010607
references.citation: Gastrointest Endosc. 2002 Aug;56(2):275-8
references.pmid: 12145612
references.citation: Hum Pathol. 2002 May;33(5):459-65
references.pmid: 12094370
references.citation: Gastrointest Endosc. 2009 Jun;69(7):1218-23
references.pmid: 19394006
references.citation: Gastrointest Endosc. 2002 Jan;55(1):37-43
references.pmid: 11756912
references.citation: Gastrointest Endosc. 2000 Feb;51(2):184-90
references.pmid: 10650262
references.citation: World J Gastroenterol. 2014 Mar 7;20(9):2176-85
references.pmid: 24605016
references.citation: Gastrointest Endosc. 2011 Jun;73(6):1189-96
references.pmid: 21420083
references.citation: Gastrointest Endosc. 2010 Jun;71(7):1307-13
references.pmid: 20417504
references.citation: Endoscopy. 2004 May;36(5):397-401
references.pmid: 15100946
references.citation: Endoscopy. 2014 Dec;46(12):1056-62
references.pmid: 25098611
references.citation: Scand J Gastroenterol. 2014 Mar;49(3):347-54
references.pmid: 24325591
references.citation: Gastrointest Endosc. 2004 Aug;60(2):267-79
references.pmid: 15278063
references.citation: Am J Clin Pathol. 2003 Sep;120(3):351-67
references.pmid: 14502798
references.citation: Gastrointest Endosc. 1994 Nov-Dec;40(6):694-9
references.pmid: 7859967
references.citation: Endoscopy. 2011 Oct;43(10 ):897-912
references.pmid: 21842456
references.citation: Gastrointest Endosc. 2006 Oct;64(4):505-11
references.pmid: 16996340
references.citation: Endoscopy. 2009 Apr;41(4):329-34
references.pmid: 19340737
references.citation: Cancer. 2001 Aug 25;93(4):269-75
references.pmid: 11507701
references.citation: Endoscopy. 2001 Jun;33(6):478-83
references.pmid: 11437039
references.citation: Endoscopy. 2005 Jul;37(7):635-45
references.pmid: 16010608
references.citation: Endoscopy. 2012 Feb;44(2):190-206
references.pmid: 22180307
references.citation: Gastrointest Endosc. 2010 May;71(6):913-9
references.pmid: 20226456
references.citation: Clin Endosc. 2012 Jun;45(2):117-23
references.pmid: 22866250
references.citation: World J Gastroenterol. 2012 May 21;18(19):2357-63
references.pmid: 22654426
references.citation: Gastrointest Endosc. 2009 Aug;70(2):254-61
references.pmid: 19482280
references.citation: Endoscopy. 2010 Apr;42(4):292-9
references.pmid: 20354939