title: The use of equine surfactant and positive pressure ventilation to treat a premature alpaca cria with severe hypoventilation and hypercapnia.
abstract: A 5-hour-old, premature alpaca cria was presented with failure to nurse, weakness, hypoglycemia, hypercapnia, and respiratory distress. The cria was treated with 3 doses of fresh, crude equine surfactant, positive pressure ventilation, and supplemental intranasal oxygen. Recovery to discharge was uneventful, and the cria regained apparently normal respiratory function. Three years after hospital discharge, the alpaca was a healthy adult.
authors.affiliation: Department of Veterinary Population Medicine (Tinkler, Firshman), the Department of Clinical Sciences (Quandt, Mathews), College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 55108, USA.
authors.forename: Stacy H
authors.initials: SH
authors.lastname: Tinkler
authors.affiliation: Department of Veterinary Population Medicine (Tinkler, Firshman), the Department of Clinical Sciences (Quandt, Mathews), College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 55108, USA.
authors.forename: Lindsey A
authors.initials: LA
authors.lastname: Mathews
authors.affiliation: Department of Veterinary Population Medicine (Tinkler, Firshman), the Department of Clinical Sciences (Quandt, Mathews), College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 55108, USA.
authors.forename: Anna M
authors.initials: AM
authors.lastname: Firshman
authors.affiliation: Department of Veterinary Population Medicine (Tinkler, Firshman), the Department of Clinical Sciences (Quandt, Mathews), College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 55108, USA.
authors.forename: Jane E
authors.initials: JE
authors.lastname: Quandt
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002161:Camelids, New World; D006935:Hypercapnia / Q000628:therapy / Q000662:veterinary; D007040:Hypoventilation / Q000628:therapy / Q000662:veterinary*; D010100:Oxygen / Q000627:therapeutic use; D011175:Positive-Pressure Respiration / Q000662:veterinary*; D047928:Premature Birth; D011663:Pulmonary Surfactants / Q000627:therapeutic use*
chemical_list: D011663:Pulmonary Surfactants; D010100:Oxygen
references.citation: Theriogenology. 2007 Jun;67(9):1455-62
references.pmid: 17448529
references.citation: J Appl Physiol (1985). 2003 Feb;94(2):770-83
references.pmid: 12433851
references.citation: Paediatr Child Health. 2005 Feb;10(2):109-16
references.pmid: 19668609
references.citation: Pediatrics. 2011 Dec;128(6):e1588-95
references.pmid: 22123870
references.citation: Paediatr Drugs. 2006;8(3):179-88
references.pmid: 16774297
references.citation: J Vet Intern Med. 2008 Mar-Apr;22(2):462-6
references.pmid: 18371034
references.citation: J Vet Emerg Crit Care (San Antonio). 2010 Apr 1;20(2):258-63
references.pmid: 20487255
references.citation: Curr Pharm Des. 2012;18(21):3034-45
references.pmid: 22564297
references.citation: Pediatrics. 2005 Aug;116(2):392-9
references.pmid: 16061594
references.citation: Vet Clin North Am Food Anim Pract. 2009 Jul;25(2):407-21
references.pmid: 19460648
references.citation: J Am Vet Med Assoc. 2008 Jul 15;233(2):289-93
references.pmid: 18627236
references.citation: Can Vet J. 2011 Jul;52(7):784-7
references.pmid: 22210945
references.citation: J Vet Intern Med. 2009 Mar-Apr;23(2):227-42
references.pmid: 19192153
references.citation: Mol Med. 2011 Mar-Apr;17(3-4):293-307
references.pmid: 21046059
references.citation: Best Pract Res Clin Anaesthesiol. 2010 Sep;24(3):375-86
references.pmid: 21033014
references.citation: Vet Clin North Am Food Anim Pract. 2009 Jul;25(2):367-84
references.pmid: 19460646
references.citation: J Vet Intern Med. 2006 Nov-Dec;20(6):1402-7
references.pmid: 17186857
references.citation: Am J Vet Res. 1987 Oct;48(10):1472-6
references.pmid: 3674556