title: Synthesis, Spectroscopic Properties and Antioxidant Activity of Bis-Hydrazones and Schiff's bases Derived from Terephthalic Dihydrazide.
abstract: A series of novel Schiff base containing bis-1,2,4-triazole and bis-hydrazone derived from terephthalic dihydrazide was synthesized. All the newly synthesized compounds were characterized by (1)H, (13)C NMR, mass spectra, FTIR and elemental analysis. UV-vis spectra and fluorescent spectra of the compounds were recorded. The effect of substituent such as electron withdrawing and electron donating groups on the fluorescent spectra was studied. Also, the comparative discussion on fluorescent spectra of Schiff's base and hydrazones has been described. The antioxidant activity of the compounds revealed that compound 5c and 5f are the most potent compounds in this series.
authors.affiliation: Department of Studies in Chemistry, Mangalore University, Mangalagangothri, 574199, Karnataka, India.
authors.forename: H S Vidyashree
authors.initials: HS
authors.lastname: Jois
authors.forename: Balakrishna
authors.initials: B
authors.lastname: Kalluraya
authors.forename: T
authors.initials: T
authors.lastname: Vishwanath
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology; D006835:Hydrazones / Q000737:chemistry* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D010795:Phthalic Acids / Q000737:chemistry*; D012545:Schiff Bases / Q000737:chemistry* / Q000494:pharmacology; D017550:Spectroscopy, Fourier Transform Infrared; D014230:Triazoles / Q000737:chemistry* / Q000494:pharmacology
chemical_list: C000605979:5,5'-benzene-1,4-bis(4-((4-fluorophenylmethylidene)amino)-4H-1,2,4-triazole-3-thiol); C000605980:5,5'-benzene-1,4-bis(4-((4-nitrophenylmethylidene)amino)-4H-1,2,4-triazole-3-thiol); D000975:Antioxidants; D006835:Hydrazones; D010795:Phthalic Acids; D012545:Schiff Bases; D014230:Triazoles; C011363:terephthalic acid
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