title: Gastritis cystica profunda in a previously unoperated stomach: a case report.
abstract: Gastritis cystica profunda is a relatively rare disease, usually observed at anastomotic sites in stomachs of patients that have undergone gastric procedures. We present the rare case of an elevated lesion in the anterior wall of the gastric antrum of a 43-year-old Chinese woman who had never undergone gastric surgery and had no gastrointestinal tract symptoms. Although the physical examination and laboratory data showed no abnormalities, endoscopic ultrasonography revealed an anechoic cystic structure. Abdominal computed tomography and magnetic resonance imaging showed the gastric wall of the greater curvature of the antrum was markedly and irregularly thickened, and mild to moderate enhancement was observed around the lesion with no enhancement in the central portion, suggestive of a gastrointestinal stromal tumor. The patient underwent a distal gastric resection of the 2.5 cm × 1.5 cm lesion. A postoperative pathologic examination showed dilated cystic glands in the muscularis mucosa and submucosal layers and erosion of the mucosal surface of the tumor, confirming the diagnosis of gastritis cystica profunda without malignancy.
authors.affiliation: Xiong-Fei Yu, Li-Wen Guo, Shi-Tu Chen, Li-Song Teng, Department of Surgical Oncology, The 1 Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
authors.forename: Xiong-Fei
authors.initials: XF
authors.lastname: Yu
authors.affiliation: Xiong-Fei Yu, Li-Wen Guo, Shi-Tu Chen, Li-Song Teng, Department of Surgical Oncology, The 1 Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
authors.forename: Li-Wen
authors.initials: LW
authors.lastname: Guo
authors.affiliation: Xiong-Fei Yu, Li-Wen Guo, Shi-Tu Chen, Li-Song Teng, Department of Surgical Oncology, The 1 Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
authors.forename: Shi-Tu
authors.initials: ST
authors.lastname: Chen
authors.affiliation: Xiong-Fei Yu, Li-Wen Guo, Shi-Tu Chen, Li-Song Teng, Department of Surgical Oncology, The 1 Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China.
authors.forename: Li-Song
authors.initials: LS
authors.lastname: Teng
mesh_terms: D000328:Adult; D001706:Biopsy; D003560:Cysts / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D019160:Endosonography; D005260:Female; D005743:Gastrectomy; D005753:Gastric Mucosa / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005773:Gastroscopy; D006801:Humans; D011706:Pyloric Antrum / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D013272:Stomach Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed
keywords: Gastritis cystica profunda; Hyperplastic polyp; Stomach
references.citation: Cancer. 2012 Nov 1;118(21):5227-33
references.pmid: 22511405
references.citation: World J Gastroenterol. 2013 Feb 28;19(8):1314-7
references.pmid: 23483772
references.citation: Ir J Med Sci. 2011 Dec;180(4):929-30
references.pmid: 20972841
references.citation: Dig Dis Sci. 2003 Nov;48(11):2153-8
references.pmid: 14705821
references.citation: Cancer. 1972 Jan;29(1):205-9
references.pmid: 5007382
references.citation: Clin Endosc. 2013 Sep;46(5):568-71
references.pmid: 24143322
references.citation: Gastric Cancer. 2000 Dec 27;3(3):165-170
references.pmid: 11984732
references.citation: Cancer. 1975 Aug;36(2):606-14
references.pmid: 1157023
references.citation: Carcinogenesis. 1995 Aug;16(8):1747-51
references.pmid: 7634399
references.citation: Gastrointest Endosc. 2013 May;77(5):821-2; discussion 822
references.pmid: 23433598
references.citation: PLoS One. 2010;5(7):e11451
references.pmid: 20625512
references.citation: Endoscopy. 2012;44 Suppl 2 UCTN:E138-9
references.pmid: 22619037
references.citation: World J Surg Oncol. 2014;12:133
references.pmid: 24885818
references.citation: Kurume Med J. 2000;47(3):243-8
references.pmid: 11059228
references.citation: Gastrointest Endosc. 2006 Apr;63(4):716-7
references.pmid: 16564886
references.citation: Histopathology. 1981 Sep;5(5):535-47
references.pmid: 7286916
references.citation: Cases J. 2008 Aug 12;1(1):85
references.pmid: 18699997
references.citation: Arch Surg. 1988 Mar;123(3):372-3
references.pmid: 3341916
references.citation: Pathol Int. 2012 May;62(5):351-5
references.pmid: 22524666