title: Cyclic hypervalent iodine reagents and iron catalysts: the winning team for late-stage C-H azidation.
abstract: 1+1=3: By combining the exceptional reactivities of cyclic hypervalent iodine reagents and iron catalysts, Sharma and Hartwig achieved the azidation of CH bonds with unprecedented efficiency and selectivity. The late-stage introduction of azides into complex bioactive molecules will greatly facilitate the synthesis of analogues and accelerate the discovery of new chemical entities.
authors.affiliation: Laboratory of Catalysis and Organic Synthesis, Ecole Polytechnique Fédérale de Lausanne, EPFL SB ISIC LCSO, BCH 4306, 1015 Lausanne (Switzerland) http://lcso.epfl.ch/
authors.forename: Maria Victoria
authors.initials: MV
authors.lastname: Vita
authors.forename: Jerome
authors.initials: J
authors.lastname: Waser
keywords: CH functionalization; azides; hypervalent iodine; iron catalysis; radicals