title: [Evaluating the mitochondrial dna copy number in leukocytes and adipocytes from metabolic syndrome patients: pilot study].
abstract: The metabolic syndrome is a complex of metabolic, hormonal and clinical disorders. Defects in mitochondrial functions play an important role in the metabolic syndrome pathogenesis. Here, mitochondrial DNA (mtDNA) copy number variations were evaluated different fat tissue and peripheral blood leukocyte samples from metabolic syndrome patients ranked by, body mass indexes. It was elucidated a tendency in decreasing the mtDNA copy number with increasing a body mass index.
authors.forename: O I
authors.initials: OI
authors.lastname: Mozheĭ
authors.forename: P A
authors.initials: PA
authors.lastname: Zatolokin
authors.forename: M A
authors.initials: MA
authors.lastname: Vasilenko
authors.forename: L S
authors.initials: LS
authors.lastname: Litvinova
authors.forename: E V
authors.initials: EV
authors.lastname: Kirienkova
authors.forename: I O
authors.initials: IO
authors.lastname: Mazunin
mesh_terms: D017667:Adipocytes / Q000502:physiology*; D000273:Adipose Tissue / Q000502:physiology; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D016022:Case-Control Studies; D056915:DNA Copy Number Variations; D004272:DNA, Mitochondrial / Q000097:blood / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000235:genetics*; D008875:Middle Aged; D009765:Obesity / Q000235:genetics; D010865:Pilot Projects; D055815:Young Adult
chemical_list: D004272:DNA, Mitochondrial