title: The primate amygdala in social perception - insights from electrophysiological recordings and stimulation.
abstract: The role of the amygdala in emotion and social perception has been intensively investigated primarily through studies using functional magnetic resonance imaging (fMRI). Recently, this topic has been examined using single-unit recordings in both humans and monkeys, with a focus on face processing. The findings provide novel insights, including several surprises: amygdala neurons have very long response latencies, show highly nonlinear responses to whole faces, and can be exquisitely selective for very specific parts of faces such as the eyes. In humans, the responses of amygdala neurons correlate with internal states evoked by faces, rather than with their objective features. Current and future studies extend the investigations to psychiatric illnesses such as autism, in which atypical face processing is a hallmark of social dysfunction.
authors.affiliation: Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA. Electronic address: ueli.rutishauser@cshs.org.
authors.forename: Ueli
authors.initials: U
authors.lastname: Rutishauser
authors.affiliation: Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
authors.forename: Adam N
authors.initials: AN
authors.lastname: Mamelak
authors.affiliation: Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
authors.forename: Ralph
authors.initials: R
authors.lastname: Adolphs
mesh_terms: D000679:Amygdala / Q000098:blood supply / Q000166:cytology* / Q000502:physiology*; D000818:Animals; D046690:Deep Brain Stimulation / Q000379:methods; D004594:Electrophysiology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D009474:Neurons / Q000502:physiology*; D010100:Oxygen / Q000097:blood; D010812:Physical Stimulation; D011323:Primates; D012938:Social Perception
chemical_list: D010100:Oxygen
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