title: Metastases to oro-maxillo-facial region from distant sites: are they so rare? A single centre 8-years experience.
abstract: OBJECTIVE
  The goal of our study is investigate the frequency of metastasis to oro-maxillo-facial region to understand if they are really so rare.
  
  
  METHODS
  In this eight year's retrospective study (2004-2012) we collected 15 cases of metastasis localized in the maxilla-facial region from distant primary tumor.
  
  
  RESULTS
  Our results show breast and kidney as the most frequent primary site (40% and 20% respectively), adenocarcinoma as most common histological type (60%). Bone involvement has found to be much frequent than the soft tissue one (53.3%). The mandible (5/15 cases) is more affected than the maxilla, and most common interested subsites are molar and retromolar region. In our study we found only one case of unknown primary tumor, it was a mandibular bone metastasis from a renal clear cell carcinoma.
  
  
  CONCLUSIONS
  Finally, according to our results and considering the increase of survival in cancer disease, even if metastases to oro- maxilla- facial region from distant sites are not frequent, it is important to suspect secondary lesions both in patients that was referred a tumor in their medical history and in those that present a head and neck lesion.
authors.forename: Valentina
authors.initials: V
authors.lastname: Terenzi
authors.forename: Andrea
authors.initials: A
authors.lastname: Cassoni
authors.forename: Oriana Rajabtork
authors.initials: OR
authors.lastname: Zadeh
authors.forename: Ingrid
authors.initials: I
authors.lastname: Raponi
authors.forename: Marco
authors.initials: M
authors.lastname: Della Monaca
authors.forename: Davina
authors.initials: D
authors.lastname: Bartoli
authors.forename: Andrea
authors.initials: A
authors.lastname: Battisti
authors.forename: Valentino
authors.initials: V
authors.lastname: Valentini
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology / Q000556:secondary*; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology; D002292:Carcinoma, Renal Cell / Q000453:epidemiology / Q000556:secondary; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000473:pathology; D006258:Head and Neck Neoplasms / Q000453:epidemiology / Q000556:secondary*; D006801:Humans; D007573:Jaw Neoplasms / Q000453:epidemiology / Q000556:secondary; D007680:Kidney Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000453:epidemiology / Q000556:secondary; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000453:epidemiology / Q000556:secondary