title: Stereotactic body radiotherapy for oligometastases confined to the para-aortic region: clinical outcomes and the significance of radiotherapy field and dose.
abstract: We retrospectively reviewed 88 patients with oligometases in the para-aortic region from any controlled primary tumor site who were treated with stereotactic body radiotherapy (SBRT). The 5-year local control, disease-free survival, and overall survival rates were 83%, 31%, and 41%, respectively. A 90% tumor-control probability was predicted at a biological effective dose of 90 Gy. Severe gastrointestinal toxicities (grade ≥3) were observed in 2 of 88 patients (1%). The results of this study are limited by the retrospective nature of the study but could serve as the background and rationale for future prospective trials on SBRT-based treatment for oligometastses.
authors.affiliation: 1Department of Radiation Oncology, Korea Institute of Radiological & Medical Sciences , Seoul , Korea.
authors.forename: Young-Seok
authors.initials: YS
authors.lastname: Seo
authors.forename: Mi-Sook
authors.initials: MS
authors.lastname: Kim
authors.forename: Chul-Koo
authors.initials: CK
authors.lastname: Cho
authors.forename: Hyung-Jun
authors.initials: HJ
authors.lastname: Yoo
authors.forename: Won-Il
authors.initials: WI
authors.lastname: Jang
authors.forename: Kum-Bae
authors.initials: KB
authors.lastname: Kim
authors.forename: Dong-Han
authors.initials: DH
authors.lastname: Lee
authors.forename: Sun-Mi
authors.initials: SM
authors.lastname: Moon
authors.forename: Hoy-Rak
authors.initials: HR
authors.lastname: Lee
mesh_terms: D000368:Aged; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D011379:Prognosis; D016634:Radiosurgery; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome
keywords: Outcomes research; Prognosis and response predictions; Radiation oncology