title: Convenient access to polyfunctional pyrazoles via a highly efficient and regioselective multicomponent reaction.
abstract: A multicomponent reaction has been developed for the synthesis of polyfunctional pyrazole derivatives from readily available arylglyoxal monohydrates, tosylhydrazine, and aldehydes or ketones. This synthetic method has significant advantages in broad substrate scope, excellent regioselectivity, and simple operation.
authors.forename: Wen-Ming
authors.initials: WM
authors.lastname: Shu
authors.forename: Kai-Lu
authors.initials: KL
authors.lastname: Zheng
authors.forename: Jun-Rui
authors.initials: JR
authors.lastname: Ma
authors.forename: Hui-Ying
authors.initials: HY
authors.lastname: Sun
authors.forename: Mei
authors.initials: M
authors.lastname: Wang
authors.affiliation: ‡State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China.
authors.forename: An-Xin
authors.initials: AX
authors.lastname: Wu
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D006037:Glyoxal / Q000031:analogs & derivatives / Q000737:chemistry; D006834:Hydrazines / Q000737:chemistry; D007659:Ketones / Q000737:chemistry; D015394:Molecular Structure; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D006834:Hydrazines; D007659:Ketones; D011720:Pyrazoles; D006037:Glyoxal