title: [The pathogenetic substantiation of new therapeutic approach to the treatment of secondary osteoarthritis in patients with rheumatoid arthritis with basis therapy].
abstract: The article concerns the efficacy of the use of new therapeutic approach in the therapy of secondary osteoarthritis in patients with rheumatoid arthritis. The dynamic of Cartilage Oligomeric Matrix Protein, activity of the disease on DAS28, cytokine profile was estimated. The analysis of the results showed the advantages of the use of inhibitor of IL-1 combined with laser therapy in the treatment of secondary osteoarthritis in patients with rheumatoid arthritis.
authors.forename: I A
authors.initials: IA
authors.lastname: Starodubtseva
authors.forename: L N
authors.initials: LN
authors.lastname: Tsvetikova
mesh_terms: D000368:Aged; D000880:Anthraquinones / Q000008:administration & dosage / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000188:drug therapy* / Q000276:immunology / Q000532:radiotherapy; D064236:Cartilage Oligomeric Matrix Protein / Q000097:blood*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007375:Interleukin-1 / Q000037:antagonists & inhibitors*; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology / Q000532:radiotherapy; D016896:Treatment Outcome
chemical_list: D000880:Anthraquinones; D064236:Cartilage Oligomeric Matrix Protein; D007375:Interleukin-1; C025292:diacerein; C577553:TSP5 protein, human