title: A 26-year-old female with metastatic primary gastrointestinal malignancy presenting as menorrhagia.
abstract: Krukenberg tumor is a metastatic malignant tumor of the ovary arising from a wide variety of primary sources, with the stomach being the most common. The presenting symptoms are non-specific and the primary source is often un-identified. Here, we describe a case of a 26-year-old Hispanic gravida 4, para 3 female who presented to our hospital with dysuria, pelvic pain and irregular, heavy menstrual cycles for three months duration. An endometrial biopsy was suggestive of carcinosarcoma. The patient underwent debulking surgery with partial cystectomy and bladder repair. A week later, she presented with hematemesis and an endoscopic biopsy revealed a diagnosis of poorly differentiated gastric adenocarcinoma. The tissue specimen obtained during the initial surgery was identified as Krukenberg tumor. The patient underwent adjuvant chemotherapy with FOLFOX along with gastrectomy with intraperitoneal chemotherapy.
authors.affiliation: Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL 60657, USA.
authors.forename: Maliha
authors.initials: M
authors.lastname: Khan
authors.affiliation: Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL 60657, USA.
authors.forename: Ravinder Pal
authors.initials: RP
authors.lastname: Bhatti
authors.affiliation: Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL 60657, USA.
authors.forename: Sarbajit
authors.initials: S
authors.lastname: Mukherjee
authors.affiliation: Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL 60657, USA.
authors.forename: Alaa M
authors.initials: AM
authors.lastname: Ali
authors.affiliation: Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL 60657, USA.
authors.forename: Alan D
authors.initials: AD
authors.lastname: Gilman
authors.affiliation: Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL 60657, USA.
authors.forename: Aibek E
authors.initials: AE
authors.lastname: Mirrakhimov
authors.affiliation: Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, IL 60657, USA.
authors.forename: Nkemakolam
authors.initials: N
authors.lastname: Iroegbu
keywords: Krukenberg tumor; menorrhagia
references.citation: Am J Obstet Gynecol. 1968 Apr 15;100(8):1062-70
references.pmid: 5643184
references.citation: Cancer Treat Res. 2007;134:357-73
references.pmid: 17633066
references.citation: Oncology. 2003;64(2):176-82
references.pmid: 12566916
references.citation: Am J Obstet Gynecol. 1965 Dec 15;93(8):1094-101
references.pmid: 4284929
references.citation: Gynecol Obstet Invest. 2002;54(4):221-7
references.pmid: 12592066
references.citation: Semin Surg Oncol. 1991 Nov-Dec;7(6):365-72
references.pmid: 1759085
references.citation: Am J Clin Pathol. 2004 Jun;121(6):884-92
references.pmid: 15198362
references.citation: Arch Pathol Lab Med. 2006 Nov;130(11):1725-30
references.pmid: 17076540
references.citation: Radiology. 1985 Jul;156(1):161-4
references.pmid: 4001405
references.citation: Adv Anat Pathol. 2006 Sep;13(5):205-27
references.pmid: 16998315
references.citation: Nebr Med J. 1972 Oct;57(10):409-15
references.pmid: 4342364
references.citation: Am J Surg Pathol. 2006 Mar;30(3):277-99
references.pmid: 16538048
references.citation: Oncology. 2000 Apr;58(3):191-7
references.pmid: 10765119
references.citation: Gynecol Oncol. 2004 Aug;94(2):477-82
references.pmid: 15297191
references.citation: Br J Surg. 2005 Mar;92(3):370-5
references.pmid: 15739249
references.citation: Oncol Rep. 2000 Jul-Aug;7(4):809-14
references.pmid: 10854549
references.citation: Ann Surg. 1998 Sep;228(3):347-54
references.pmid: 9742917