title: Mirabegron.
abstract: Mirabegron is used for the treatment of symptoms associated with overactive bladder syndrome. It selectively stimulates the β3 -adrenoreceptor, which relaxes the detrusor muscle. This improves urine storage by distension of the bladder body.
authors.affiliation: Centre for Human Drug Research, Leiden, The Netherlands.
authors.forename: Sebastiaan C
authors.identifier: http://orcid.org/0000-0003-3369-6107
authors.initials: SC
authors.lastname: Goulooze
authors.affiliation: Centre for Human Drug Research, Leiden, The Netherlands.|Leiden University, Medical Center, Leiden, The Netherlands.
authors.forename: Adam F
authors.identifier: http://orcid.org/0000-0001-7452-6222
authors.initials: AF
authors.lastname: Cohen
authors.affiliation: Centre for Human Drug Research, Leiden, The Netherlands.|Leiden University, Medical Center, Leiden, The Netherlands.
authors.forename: Robert
authors.initials: R
authors.lastname: Rissmann
mesh_terms: D000083:Acetanilides / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D058667:Adrenergic beta-3 Receptor Agonists / Q000494:pharmacology*; D006801:Humans; D009465:Neuromuscular Agents / Q000494:pharmacology*; D013844:Thiazoles / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D001743:Urinary Bladder / Q000187:drug effects*; D053201:Urinary Bladder, Overactive / Q000188:drug therapy*
chemical_list: D000083:Acetanilides; D058667:Adrenergic beta-3 Receptor Agonists; D009465:Neuromuscular Agents; D013844:Thiazoles; C520025:mirabegron
references.citation: Neurourol Urodyn. 2014 Jan;33(1):17-30
references.pmid: 24127366
references.citation: Urology. 2004 Dec;64(6 Suppl 1):2-6
references.pmid: 15621220
references.citation: Neurourol Urodyn. 2002;21(2):167-78
references.pmid: 11857671
references.citation: Eur Urol. 2015 Jan;67(1):11-4
references.pmid: 25092537
references.citation: Naunyn Schmiedebergs Arch Pharmacol. 2013 Mar;386(3):177-83
references.pmid: 23263450
references.citation: Naunyn Schmiedebergs Arch Pharmacol. 2008 Jun;377(4-6):449-62
references.pmid: 18060543
references.citation: Qual Life Res. 2015 Jul;24(7):1719-27
references.pmid: 25688038
references.citation: Rev Urol. 2003;5 Suppl 8:S3-S10
references.pmid: 16985987