title: Aortic Valve Reconstruction Using Autologous Pericardium for Aortic Stenosis.
abstract: BACKGROUND
  To determine the feasibility of original aortic valve reconstruction (AVRec) for patients with aortic stenosis (AS), 416 consecutive cases were reviewed.
  
  
  RESULTS
  AVRecs for AS were performed for 416 patients from April 2007 through April 2013. All 416 patients were retrospectively reviewed. One hundred and fourteen patients had bicuspid valves and 16 had unicuspid valves. There were 182 men and 234 women. Mean age was 71.2±12.0 years old. On preoperative echocardiography, peak pressure gradient averaged 79.0±33.6 mmHg. Surgical annular diameter was 20.1±2.8 mm. The procedure is based on independent tricuspid replacement by autologous pericardium using original sizing apparatus and template. There was no conversion to prosthetic valve replacement. There were 8 in-hospital mortalities due to non-cardiac cause. On postoperative echocardiography, peak pressure gradient averaged 21.2±10.7 mmHg 1 week after surgery and 14.3±5.0 mmHg 5.5 years after surgery. Four reoperations were done for infective endocarditis. The other 412 patients had less than mild regurgitation. No thrombo-embolic events were recorded. The mean follow-up period was 25.2±17.5 months. Freedom from reoperation was 96.7% with 73-month follow-up.
  
  
  CONCLUSIONS
  Medium-term results were excellent. Original AVRec was feasible for the patients with AS. Long-term data will be presented in the future.
authors.affiliation: Department of Cardiovascular Surgery, Toho University Ohashi Medical Center.
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Ozaki
authors.forename: Isamu
authors.initials: I
authors.lastname: Kawase
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Yamashita
authors.forename: Shin
authors.initials: S
authors.lastname: Uchida
authors.forename: Mikio
authors.initials: M
authors.lastname: Takatoh
authors.forename: So
authors.initials: S
authors.lastname: Hagiwara
authors.forename: Nagaki
authors.initials: N
authors.lastname: Kiyohara
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000401:mortality* / Q000503:physiopathology / Q000601:surgery*; D006348:Cardiac Surgical Procedures; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D010496:Pericardium; D015996:Survival Rate