title: Caprine herpesvirus 1 (CpHV-1) vaginal infection of goats: clinical efficacy of fig latex.
abstract: The latex of Ficus carica Linn. (Moraceae) has been shown to interfere with the replication of caprine herpesvirus (CpHV)-1 in vitro. The present study was undertaken to determine the efficacy of vaginal administration of fig latex in goats experimentally infected with CpHV-1. The fig latex reduced the clinical signs of the herpetic disease although it slightly influenced the titres of CpHV-1 shed. Thus, the fig latex maintained a partial efficacy in vivo.
authors.affiliation: a Department of Veterinary Medicine , University of Bari , Sp. Casamassima km 3, 70010 Valenzano , BA , Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Camero
authors.affiliation: b Department of infectious , Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità , Via Regina Elena 299, 00161 Rome , Italy.
authors.forename: Mariarosaria
authors.initials: M
authors.lastname: Marinaro
authors.affiliation: a Department of Veterinary Medicine , University of Bari , Sp. Casamassima km 3, 70010 Valenzano , BA , Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Losurdo
authors.affiliation: a Department of Veterinary Medicine , University of Bari , Sp. Casamassima km 3, 70010 Valenzano , BA , Italy.
authors.forename: Vittorio
authors.initials: V
authors.lastname: Larocca
authors.affiliation: a Department of Veterinary Medicine , University of Bari , Sp. Casamassima km 3, 70010 Valenzano , BA , Italy.
authors.forename: Livia
authors.initials: L
authors.lastname: Bodnar
authors.affiliation: a Department of Veterinary Medicine , University of Bari , Sp. Casamassima km 3, 70010 Valenzano , BA , Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Patruno
authors.affiliation: a Department of Veterinary Medicine , University of Bari , Sp. Casamassima km 3, 70010 Valenzano , BA , Italy.
authors.forename: Canio
authors.initials: C
authors.lastname: Buonavoglia
authors.affiliation: a Department of Veterinary Medicine , University of Bari , Sp. Casamassima km 3, 70010 Valenzano , BA , Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Tempesta
mesh_terms: D000818:Animals; D005260:Female; D030681:Ficus / Q000737:chemistry*; D015511:Goat Diseases / Q000188:drug therapy* / Q000821:virology; D006041:Goats; D006566:Herpesviridae Infections / Q000188:drug therapy* / Q000821:virology; D007840:Latex / Q000627:therapeutic use*; D016896:Treatment Outcome; D014623:Vaginal Diseases / Q000188:drug therapy* / Q000662:veterinary* / Q000821:virology; D018140:Varicellovirus
chemical_list: D007840:Latex
keywords: CpHV-1; Ficus carica latex; antiviral activity; goat; herpesvirus