title: Assessment of In-Stent Restenosis Using High-Definition Computed Tomography With a New Gemstone Detector.
abstract: BACKGROUND
  Until now, there have been few reports on the accuracy of in-stent restenosis (ISR) detection using high-definition computed tomography (HDCT). The purpose of this study was to assess ISR using HDCT with a new gemstone detector and to examine the diagnostic accuracy compared with invasive coronary angiography.
  
  
  RESULTS
  We evaluated 162 consecutive patients with 316 stents and the image quality (IQ) scores used to assess ISR, and analyzed whether stent strut thickness and diameter affected IQ score and assessability. In the 316 stents, 278 were diagnosed as assessable with HDCT (88.0%). IQ score for stent diameter ≥3 mm was significantly higher than that for stent diameter <3 mm, for stents with both thick struts ≥140 μm in thickness (mean IQ: 2.04±0.97 vs. 2.83±1.06, P<0.001) and thin struts <140 μm (mean IQ: 1.92±0.87 vs. 2.64±0.96, P=0.01). Assessability for stent diameter ≥3 mm was significantly higher than that for stent diameter <3 mm only for stents with thick struts (92.8% vs. 76.1%, P<0.001). Stent strut thickness, however, was not statistically significantly associated with either IQ score or assessability.
  
  
  CONCLUSIONS
  In-stent lumens have high HDCT assessability, and HDCT is useful to evaluate thick-strut stents with diameter <3 mm.
authors.affiliation: Department of Cardiology, Nagoya University Graduate School of Medicine.
authors.forename: Takuma
authors.initials: T
authors.lastname: Tsuda
authors.forename: Hideki
authors.initials: H
authors.lastname: Ishii
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ichimiya
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kanashiro
authors.forename: Jyunji
authors.initials: J
authors.lastname: Watanabe
authors.forename: Mikito
authors.initials: M
authors.lastname: Takefuji
authors.forename: Toru
authors.initials: T
authors.lastname: Aoyama
authors.forename: Susumu
authors.initials: S
authors.lastname: Suzuki
authors.forename: Akihito
authors.initials: A
authors.lastname: Tanaka
authors.forename: Tatsuaki
authors.initials: T
authors.lastname: Matsubara
authors.forename: Toyoaki
authors.initials: T
authors.lastname: Murohara
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography / Q000295:instrumentation / Q000379:methods; D005260:Female; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods