title: Hybrid encapsulation structures based on β-carotene-loaded nanoliposomes within electrospun fibers.
abstract: Hybrid encapsulation structures based on β-carotene-loaded nanoliposomes incorporated within the polymeric ultrathin fibers produced through electrospinning were developed to improve the photostability of the antioxidant. These novel materials were intended to incorporate β-carotene into water-based food formulations, overcoming the existing limitations associated with its hydrophobic character. Initially, both empty and antioxidant-loaded nanoliposomes were developed and incorporated into polyvinyl alcohol (PVOH) and polyethylene oxide (PEO) solutions. The changes in the solution properties were evaluated to determine their effects on the electrospinning processing. The mixed polymer solutions were subsequently electrospun to produce hybrid nanoliposome-loaded ultrathin fibers. FTIR analysis confirmed the presence of phospholipid molecules inside the electrospun fibers. These ultrathin fibers were evaluated regarding their morphology, diameter, internal β-carotene distribution and stability against UV irradiation. Liposomal release studies from the electrospun fibers were also undertaken, confirming the presence of the liposomal structures after dissolving the electrospun fibers in water.
authors.affiliation: School of Chemical Engineering, University of Campinas, UNICAMP P.O. Box 6066, 13083-970, Campinas-SP, Brazil.
authors.forename: Rafael Henrique
authors.initials: RH
authors.lastname: de Freitas Zômpero
authors.affiliation: Novel Materials and Nanotechnology Group, Institute of Agrochemistry and Food Technology, IATA, 46980 Paterna, Valencia, Spain.
authors.forename: Amparo
authors.initials: A
authors.lastname: López-Rubio
authors.affiliation: Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo (USP), Pirassununga, SP, Brazil.
authors.forename: Samantha Cristina
authors.initials: SC
authors.lastname: de Pinho
authors.affiliation: School of Chemical Engineering, University of Campinas, UNICAMP P.O. Box 6066, 13083-970, Campinas-SP, Brazil; Novel Materials and Nanotechnology Group, Institute of Agrochemistry and Food Technology, IATA, 46980 Paterna, Valencia, Spain; Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo (USP), Pirassununga, SP, Brazil.
authors.forename: José María
authors.initials: JM
authors.lastname: Lagaron
authors.affiliation: School of Chemical Engineering, University of Campinas, UNICAMP P.O. Box 6066, 13083-970, Campinas-SP, Brazil. Electronic address: latorre@feq.unicamp.br.
authors.forename: Lucimara Gaziola
authors.initials: LG
authors.lastname: de la Torre
mesh_terms: D008081:Liposomes; D008855:Microscopy, Electron, Scanning; D049329:Nanostructures; D017550:Spectroscopy, Fourier Transform Infrared; D019207:beta Carotene / Q000737:chemistry*
chemical_list: D008081:Liposomes; D019207:beta Carotene
keywords: Nanofiber; Nanoliposomes; Polyethylene oxide; Polyvinyl alcohol