title: Management of acne vulgaris with hormonal therapies in adult female patients.
abstract: Acne vulgaris is a very common condition affecting up of 93% of adolescents. Although rare, this disease may persist in adulthood. In adult women with acne (those older than 25 years old), this condition is particularly relevant because of the refractory to conventional therapies, which makes acne a challenge for dermatologists in this group of patients. In order to its potential risk for chronicity and the involvement of visible anatomical sites such as face and upper torso, acne has been associated with a wide spectrum of psychological and social dysfunction such as depression, anxiety, suicidal ideation, somatization, and social inhibition. In particular, adult women with acne have been shown to be adversely impacted by the effect of acne on their quality of life. For the last four decades, dermatologists have used hormonal therapies for the management of acne vulgaris in adult women, which are considered a rational choice given the severity and chronicity of this condition in this group of patients. The aim of this work is to review the hormonal drugs for management of acne.
authors.affiliation: Department of Dermatology, Infanta Margarita Hospital, Córdoba, Spain.
authors.forename: Husein
authors.initials: H
authors.lastname: Husein-ElAhmed
mesh_terms: D000152:Acne Vulgaris / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D000328:Adult; D003278:Contraceptives, Oral, Hormonal / Q000627:therapeutic use; D017281:Cost of Illness; D017373:Cyproterone Acetate / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005485:Flutamide / Q000627:therapeutic use; D006728:Hormones / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D011788:Quality of Life; D012074:Remission Induction; D013148:Spironolactone / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D003278:Contraceptives, Oral, Hormonal; D003879:Dermatologic Agents; D006728:Hormones; D013148:Spironolactone; D017373:Cyproterone Acetate; D005485:Flutamide
keywords: acne; adult women; hormonal therapy