title: [Two cases of cerebral infarction due to focal irradiation for glioma in adults].
abstract: Radiation-induced vasculopathy is a complication of radiation therapy. Most reports regarding post-irradiation ischemic stroke with intracranial tumors are restricted to pediatric cases. Here we report two adult cases of delayed brain infarction due to anterior and middle cerebral artery stenosis or occlusion seemingly caused by focal radiation therapy for malignant glioma. Although radiation-induced ischemic stroke in adults is relatively uncommon, it is possible that the morbidity rate of radiation-induced stroke in malignant glioma patients will increase with prolonged survival due to advances in therapy. Therefore, regular evaluation of intracranial vasculature following radiation therapy is necessary.
authors.affiliation: Department of Neurosurgery, Kobe University Graduate School of Medicine.
authors.forename: Noriaki
authors.initials: N
authors.lastname: Minami
authors.forename: Katsu
authors.initials: K
authors.lastname: Mizukawa
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Iwahashi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nagashima
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tanaka
authors.forename: Takashi
authors.initials: T
authors.lastname: Sasayama
authors.forename: Kohkichi
authors.initials: K
authors.lastname: Hosoda
authors.forename: Naritoshi
authors.initials: N
authors.lastname: Mukumoto
authors.forename: Ryohei
authors.initials: R
authors.lastname: Sasaki
authors.forename: Eiji
authors.initials: E
authors.lastname: Kohmura
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000532:radiotherapy*; D002533:Cerebral Angiography; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D005260:Female; D005910:Glioma / Q000532:radiotherapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D011832:Radiation Injuries / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011878:Radiotherapy / Q000009:adverse effects; D015899:Tomography, Emission-Computed, Single-Photon