title: Electrochemical paper-based microfluidic devices.
abstract: Self-pumping porous microfluidic devices have attracted significant interest because of their low cost and broad applicability in point-of-care and low resource settings. One limitation of many of the devices is sensitivity and selectivity for detection. Electrochemistry can provide a sensitive, selective detection method while still using low cost, portable instrumentation as typified by handheld glucometers. Here, the development of electrochemical paper-based analytical devices (ePADs) is reviewed. Given the importance of electrode geometry and composition, fabrication methods are reviewed first. This is followed by a review of example applications demonstrated for ePADs. Finally, major accomplishments and future directions are summarized.
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, CO, USA.
authors.forename: Jaclyn
authors.initials: J
authors.lastname: Adkins
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, CO, USA.
authors.forename: Katherine
authors.initials: K
authors.lastname: Boehle
authors.affiliation: Department of Chemistry, Colorado State University, Fort Collins, CO, USA.|Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO, USA.|School of Biomedical Engineering, Colorado State University, Fort Collins, CO, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Henry
mesh_terms: D055664:Electrochemical Techniques / Q000295:instrumentation*; D004867:Equipment Design; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D036103:Nanotechnology; D010209:Paper
keywords: Electrochemical paper-based microfluidics; Electrochemistry; Microfluidics; Paper-based microfluidic devices