title: Epidemiology and clinical management of tuberculosis in children in Canada.
abstract: Although often regarded as a foreign disease, latent tuberculosis or tuberculosis disease will be encountered in many clinical situations by the Canadian child health practitioner. There are key differences between tuberculosis in children and adults. In the present article, the changing epidemiology of tuberculosis in children in Canada and around the world, the pathogenesis of infection, diagnostic tests, and clinical management of childhood latent tuberculosis and tuberculosis disease are reviewed.
authors.affiliation: Division of Infectious Diseases, Toronto, Ontario; ; Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario; ; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario;
authors.forename: Shaun K
authors.initials: SK
authors.lastname: Morris
authors.affiliation: Department of Microbiology and Immunology and Department of Pediatrics, CHU Sainte-Justine, University of Montreal, Montreal, Quebec;
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Demers
authors.affiliation: Division of Infectious Diseases, Toronto, Ontario;
authors.forename: Ray
authors.initials: R
authors.lastname: Lam
authors.affiliation: Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario;
authors.forename: Lisa G
authors.initials: LG
authors.lastname: Pell
authors.affiliation: Faculty of Medicine, University of Toronto, Toronto, Ontario.
authors.forename: Ryan Jp
authors.initials: RJ
authors.lastname: Giroux
authors.affiliation: Division of Infectious Diseases, Toronto, Ontario; ; Department of Pediatrics, Faculty of Medicine, University of Toronto, Toronto, Ontario;
authors.forename: Ian
authors.initials: I
authors.lastname: Kitai
keywords: Children; Diagnosis; Mycobacterium tuberculosis; Pathogenesis; Treatment; Tuberculosis
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