title: Bilateral acute retinal necrosis due to varicella zóster virus in an elderly patient.
abstract: METHODS
  The case is reported of acute retinal necrosis with bilateral involvement due to Varicella Zoster virus in a 77 year-old man. Polymerase chain reaction (PCR) of aqueous humor was positive for Varicella Zoster virus (VZV). He developed a Kyrieleis' vasculitis a month after the starting treatment, when the PCR analysis was negative.
  
  
  CONCLUSIONS
  PCR is a quick and safe technique, with a high sensitivity and specificity of 97%, useful to diagnose and monitor the viral activity. The intervention must be urgent, due to the dramatically rapid evolution. Oral famciclovir oral is good alternative owing to its bioavailability.
authors.affiliation: Servicio de Oftalmología, Hospital de la Axarquía, Málaga, España. Electronic address: olgavillena@yahoo.es.
authors.forename: O
authors.initials: O
authors.lastname: Villena-Irigoyen
authors.affiliation: Servicio de Oftalmología, Hospital de la Axarquía, Málaga, España.
authors.forename: L
authors.initials: L
authors.lastname: Echevarría-Lucas
authors.affiliation: Servicio de Oftalmología, Hospital de Motril, Granada, España.
authors.forename: M
authors.initials: M
authors.lastname: Castro-Gómez
authors.affiliation: Servicio de Oftalmología, Hospital de Motril, Granada, España.
authors.forename: R M
authors.initials: RM
authors.lastname: Bellido-Muñoz
mesh_terms: D000368:Aged; D001082:Aqueous Humor / Q000821:virology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000276:immunology; D006563:Herpes Zoster Ophthalmicus / Q000150:complications*; D014645:Herpesvirus 3, Human / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D016133:Polymerase Chain Reaction; D011471:Prostatic Neoplasms / Q000150:complications / Q000276:immunology; D015882:Retinal Necrosis Syndrome, Acute / Q000209:etiology*; D031300:Retinal Vasculitis / Q000209:etiology; D066167:Slit Lamp
keywords: Acute retinal necrosis; Famciclovir; Kyrieleis’ vasculitis; Necrosis retiniana aguda; Necrotizing retinitis; Polymerase chain reaction; Reacción en cadena de la polimerasa; Retinal necrosis; Retinitis necrosantes; Vasculitis de Kyrieleis