title: Toxic anterior segment syndrome after uncomplicated cataract surgery possibly associated with intracamaral use of cefuroxime.
abstract: OBJECTIVE
  To report toxic anterior segment syndrome (TASS) after cataract surgery possibly associated with intracameral use of cefuroxime.
  
  
  METHODS
  We conducted a retrospective chart review and analysis on the pre- and postoperative conditions of the subjects who had developed TASS.
  
  
  RESULTS
  The patient group consisted of 17 patients. Tyndallization and fibrin fibers were positive in all eyes. In four eyes, hypopyon formation developed. These reactions diminished on the third day and fully resolved 1 week after the operations with the use of intensive topical steroid and mydriatic therapy. To determine the etiology of TASS, infusion fluid, viscoelastics, and intracameral antibiotic agent were changed respectively. After changing intracameral antibiotic agent from cefuroxime axetile to moxifloxacin no new cases of TASS were diagnosed.
  
  
  CONCLUSIONS
  All agents injected into the anterior chamber can cause TASS. Ophthalmologists and operating room staff need to pay careful attention to all drugs and irrigating solutions.
authors.affiliation: Sakarya University Education and Research Hospital, Sakarya, Turkey.
authors.forename: Burçin
authors.initials: B
authors.lastname: Çakır
authors.affiliation: Sakarya University Education and Research Hospital, Sakarya, Turkey.
authors.forename: Erkan
authors.initials: E
authors.lastname: Celik
authors.affiliation: Sakarya University Education and Research Hospital, Sakarya, Turkey.
authors.forename: Nilgün Özkan
authors.initials: NÖ
authors.lastname: Aksoy
authors.affiliation: Sakarya University Education and Research Hospital, Sakarya, Turkey.
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Bursalı
authors.affiliation: Sakarya University Education and Research Hospital, Sakarya, Turkey.
authors.forename: Turgay
authors.initials: T
authors.lastname: Uçak
authors.affiliation: Sakarya University Education and Research Hospital, Sakarya, Turkey.
authors.forename: Erdinç
authors.initials: E
authors.lastname: Bozkurt
authors.affiliation: Sakarya University Education and Research Hospital, Sakarya, Turkey.
authors.forename: Gursoy
authors.initials: G
authors.lastname: Alagoz
keywords: drug toxicity; fibrin reaction; phacoemulsification
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