title: Comparative factor analysis of the effect of postoperative peripheral parenteral nutrition on recovery of right lobe liver donors.
abstract: OBJECTIVE
  Intensive nutritional support can reduce the catabolic response, improve protein synthesis, and promote liver regeneration. This study examined whether postoperative peripheral parenteral nutrition may improve recovery and reduce the length of hospital stay in right lobe liver donors.
  
  
  METHODS
  In this retrospective study, we enrolled liver donors with residual liver volume < 50%. Donors were classified into 2 groups: donors who received (n = 44) or did not receive (n = 40) postoperative peripheral parenteral nutrition. Liver function tests included alanine aminotransferase and total bilirubin levels, and postoperative complications included pleural effusion, atelectasis, and wound complications. Hospital length of stay was included as a potential risk factor for the evaluation of the effect of postoperative peripheral parenteral nutrition on recovery of right lobe liver donors.
  
  
  RESULTS
  Male sex (β, 22.04; 95% confidence interval: 6.22 - 37.86) was a significant predictor of changes in postoperative alanine aminotransferase level. Male sex (β, 0.045; 95% confidence interval: 0.16 - 37.86) and receipt of peripheral parenteral nutrition (β, -0.045; 95% confidence interval: -0.72 - 0.17) were significant predictors of changes in total bilirubin level. Postoperative atelectasis (P < .001), pleural effusion (P < .011), and total complications (P = .015) had significantly lower incidence in the peripheral parenteral nutrition than control group. Multivariate logistic regression showed that recipients of peripheral parenteral nutrition (odds ratio, 0.161; 95% confidence interval: 0.043 - 0.598) and age (odds ratio, 0.870; 95% confidence interval: 0.782 - 0.968) were significant preoperative risk factors for postoperative complications.
  
  
  CONCLUSIONS
  Postoperative peripheral parenteral nutrition is associated with a lower incidence of pleural effusion and atelectasis, a more rapid recovery of hyperbilirubinemia, and shorter length of stay in right lobe liver donors.
authors: From the Department of Nursing, Changhua Christian Hospital, Changhua; and the Department of Nursing, Central Taiwan University of Science and Technology, Taichung, Taiwan.
authors: Chia-En
authors: CE
authors: Hsieh
authors: Kuo-Hua
authors: KH
authors: Lin
authors: Chia-Cheng
authors: CC
authors: Lin
authors: Yueh-Juen
authors: YJ
authors: Hwu
authors: Ping-Yi
authors: PY
authors: Lin
authors: Hui-Chuan
authors: HC
authors: Lin
authors: Chih-Jan
authors: CJ
authors: Ko
authors: Su-Han
authors: SH
authors: Wang
authors: Yao-Li
authors: YL
authors: Chen
mesh_terms: D000328:Adult; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D007902:Length of Stay; D008099:Liver / Q000378:metabolism*; D016031:Liver Transplantation; D008297:Male; D010288:Parenteral Nutrition; D010996:Pleural Effusion / Q000517:prevention & control; D011182:Postoperative Care; D011183:Postoperative Complications; D011184:Postoperative Period; D001261:Pulmonary Atelectasis / Q000517:prevention & control; D012189:Retrospective Studies; D014019:Tissue Donors