title: Arrangement of a nanostructure array to control equilibrium and nonequilibrium transports of macromolecules.
abstract: Exploiting the nonequilibrium transport of macromolecules makes it possible to increase the separation speed without any loss of separation resolution. Here we report the arrangement of a nanostructure array in microchannels to control equilibrium and nonequilibrium transports of macromolecules. The direct observation and separation of macromolecules in the nanopillar array reported here are the first to reveal the nonequilibrium transport, which has a potential to overcome the intrinsic trade-off between the separation speed and resolution.
authors: Takao
authors: T
authors: Yasui
authors: △ERATO Higashiyama Live-Holonics Project, Graduate School of Science, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8602, Japan.
authors: Noritada
authors: N
authors: Kaji
authors: §National Institute for Materials Science, Tsukuba 305-0044, Japan.
authors: Ryo
authors: R
authors: Ogawa
authors: §National Institute for Materials Science, Tsukuba 305-0044, Japan.
authors: Shingi
authors: S
authors: Hashioka
authors: ∥Division of Biotechnology and Macromolecular Chemistry, Faculty of Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, Sapporo 060-8628, Japan.
authors: Manabu
authors: M
authors: Tokeshi
authors: §National Institute for Materials Science, Tsukuba 305-0044, Japan.
authors: Yasuhiro
authors: Y
authors: Horiike
authors: ⊥Institute of Innovation for Future Society, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.|#Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu 761-0395, Japan.
authors: Yoshinobu
authors: Y
authors: Baba
keywords: Nonequilibrium transport; macromolecules; nanopillar; nanostructure array