title: The role of parotidectomy in the treatment of auricular squamous cell carcinoma.
abstract: OBJECTIVE
  We analyze parotid specimens in patients treated with prophylactic parotidectomy for squamous cell carcinoma of the auricle greater than or equal to 2 cm to determine rates of metastasis and the efficacy of elective resection.
  
  
  METHODS
  Case series with chart review.
  
  
  METHODS
  Cancer treatment center in Fort Worth, Texas, from 1998 to 2013.
  
  
  METHODS
  The study included 104 patients between ages 36 and 97 years with primary auricular squamous cell carcinoma greater than or equal to 2 cm, with no evidence of adenopathy or parotid involvement on imaging. Patients underwent local excision and ipsilateral parotidectomy. The primary cancer was analyzed for vascular involvement, perineural invasion, and cartilage involvement, while the parotid specimen was analyzed for cancer positivity.
  
  
  RESULTS
  Thirty-nine parotid (37.5%) samples were positive for carcinoma. Of these, 16 patients had primary auricular carcinomas with vascular involvement, 17 had perineural invasion, and 4 had cartilage involvement. Thirty-two of 77 affected men and 7 of 27 affected women had positive parotid specimen. Vascular involvement (P = .0006) and perineural invasion (P = .0027) of the primary lesion were significantly higher in patients with a positive parotid specimen. Cartilage involvement and sex were not statistically significant.
  
  
  CONCLUSIONS
  Elective parotidectomy is beneficial in patients with squamous cell carcinoma of the auricle at least 2 cm in size, especially in lesions having perineural invasion and vascular involvement. For patients with positive parotid specimens, we recommend postoperative external beam radiation therapy and close surveillance.
authors: Department of Otolaryngology-Head and Neck Surgery, The New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA.
authors: Sameep
authors: S
authors: Kadakia
authors: Department of Facial Plastic and Reconstructive Surgery, Otolaryngology and Facial Plastic Surgery Associates, Fort Worth, Texas, USA.
authors: Masoud
authors: M
authors: Saman
authors: Department of Otolaryngology-Head and Neck Surgery, SUNY Downstate Medical Center, Brooklyn, New York, USA.
authors: Eli
authors: E
authors: Gordin
authors: Mohs Surgery Private Practice, Fort Worth, Texas, USA.
authors: Diego
authors: D
authors: Marra
authors: Department of Facial Plastic and Reconstructive Surgery, Otolaryngology and Facial Plastic Surgery Associates, Fort Worth, Texas, USA yducic@sbcglobal.net.
authors: Yadranko
authors: Y
authors: Ducic
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000556:secondary / Q000601:surgery*; D015331:Cohort Studies; D018572:Disease-Free Survival; D054644:Ear Auricle / Q000473:pathology / Q000601:surgery*; D004428:Ear Neoplasms / Q000473:pathology / Q000601:surgery*; D017558:Elective Surgical Procedures / Q000379:methods; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D010307:Parotid Neoplasms / Q000556:secondary* / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D016019:Survival Analysis
keywords: auricle; parotidectomy; squamous cell carcinoma