title: Organoselenium-catalyzed, hydroxy-controlled regio- and stereoselective amination of terminal alkenes: efficient synthesis of 3-amino allylic alcohols.
abstract: An efficient route to prepare 3-amino allylic alcohols in excellent regio- and stereoselectivity in the presence of bases by orangoselenium catalysis has been developed. In the absence of bases α,β-unsaturated aldehydes were formed in up to 97% yield. Control experiments reveal that the hydroxy group is crucial for the direct amination.
authors: Zhimin
authors: Z
authors: Deng
authors: Jialiang
authors: J
authors: Wei
authors: Lihao
authors: L
authors: Liao
authors: Haiyan
authors: H
authors: Huang
authors: Xiaodan
authors: X
authors: Zhao
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000498:Allyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D000586:Amination; D002384:Catalysis; D015394:Molecular Structure; D016566:Organoselenium Compounds / Q000737:chemistry*; D011412:Propanolamines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D000498:Allyl Compounds; D016566:Organoselenium Compounds; D011412:Propanolamines