title: [Detection of gingipain K in the gingival crevicular fluid of orthodontic patients].
abstract: OBJECTIVE
  To explore the correlation between gingipain K (Kgp) and inflammatory reaction of gum in the process of orthodontic treatment, and analyse the role of Kgp in the development of gingivitis during orthodontic treatment.
  
  
  METHODS
  Totally 45 orthodontic healthy teenagers were randomly chosen for the study. The subgingival plaques were collected simultaneously before orthodontic treatment and 3 months after treatment. 16S rDNA PCR technique was used to detect Porphyromonas gingivalis (P.g) and Kgp. SPSS17.0 software package was used for statistical analysis.
  
  
  RESULTS
  The detection rate of Kgp was 35.71% before orthodontic treatment and 67.86% after treatment. Positive correlation (P<0.05) was observed between Kgp and gingival inflammation.
  
  
  CONCLUSIONS
  Fixed orthodontic appliances cause plaque accumulation, accordingly slight gingiva inflammation and the increament of P.gingivalis in the early stage.
authors: Department of Stomatology, Binzhou People's Hospital. Binzhou 256603,China.E-mail:826964972@qq.com.
authors: Gang-Ling
authors: GL
authors: Yang
authors: Wei-Zhe
authors: WZ
authors: Li
authors: Zhi-Qiang
authors: ZQ
authors: Han
authors: Shui-Qing
authors: SQ
authors: Xiao
mesh_terms: D018829:Adhesins, Bacterial; D000293:Adolescent; D003546:Cysteine Endopeptidases; D003773:Dental Plaque; D000080867:Gingipain Cysteine Endopeptidases; D005881:Gingiva; D005883:Gingival Crevicular Fluid; D005891:Gingivitis; D006801:Humans; D009967:Orthodontic Appliances; D016966:Porphyromonas gingivalis
chemical_list: D018829:Adhesins, Bacterial; D000080867:Gingipain Cysteine Endopeptidases; D003546:Cysteine Endopeptidases