title: Histological assessment of pulpal responses to resin modified glass ionomer cements in human teeth.
abstract: BACKGROUND
  The biocompatibility of resin-modified glass ionomers (RMGIs) as a lining material is still under question. The present study evaluated the response of the pulp-dentin complex following application of resin-modified glass-ionomer cement, calcium hydroxide and conventional glass-ionomer in deep cavities prepared in human teeth.
  
  
  METHODS
  In this controlled clinical trial, 30 deep class V buccal cavities (3 mm × 2 mm × 2 mm) were prepared in human premolars treatment planned to be extracted for orthodontic reasons and divided into 3 groups. Groups were lined by a RMGI (Vivaglass), conventional glass Ionomer (Ionocid) and calcium hydroxide respectively. The cavities were subsequently filled with amalgam. Each group was then divided into two sub-groups according to time intervals 5 and 30 days. The patients were referred to Kerman Dental School and in accordance with orthodontic treatment plan; premolars were extracted and then prepared for histological assessment. The sections were stained with hematoxylin and eosin and periodic acid Schiff techniques. All of the samples were examined using a number of criteria including odontoblastic changes, inflammatory cells response, reactionary dentin formation and presence of microorganisms. The data were analyzed by Kruskal-Wallis and Mann-Whitney tests. P < 0.05 was considered as significant.
  
  
  RESULTS
  There was no significant difference among odontoblastic changes, reactionary dentin, presence of bacteria and inflammatory cells response of the groups (P > 0.05).
  
  
  CONCLUSIONS
  Ionocid and Vivaglass resin-modified glass ionomers can be used as lining materials in human teeth.
authors: Department of Restorative Dentistry and Oral and Dental Disease Research Center, Kerman, Iran.
authors: Ali
authors: A
authors: Eskandarizadeh
authors: Department of Oral and Maxillofacial Pathology and Oral and Dental Disease Research Center, Kerman, Iran.
authors: Molook Torabi
authors: MT
authors: Parizi
authors: Post-graduate Student of Endodontics, Yazd, Iran.
authors: Hossein
authors: H
authors: Goroohi
authors: Post-graduate Student of Restorative Dentistry, Yazd Shahid Sadooghi University of Medical Sciences, Yazd, Iran.
authors: Hamid
authors: H
authors: Badrian
authors: Dentist, Iran.
authors: Abbas
authors: A
authors: Asadi
authors: Dentist, Iran.
authors: Navid
authors: N
authors: Khalighinejad
keywords: Biocompatibility; calcium hydroxide; glass ionomer; pulp response; tertiary dentin