title: [A multifactor epidemiological analysis of risk factors for pancreatic cancer in women].
abstract: OBJECTIVE
  A multifactor analysis of risk factors for pancreas cancer in women.
  
  
  METHODS
  A case-control study was conducted in three centres in the Czech Republic (Olomouc, Ostrava, and České Budějovice) in 2006-2009. In total, 226 women (129 pancreas cancer cases, 97 controls) were included in the study. Statistical analysis was performed, the crude odds ratio (OR) was calculated, and logistic regression analysis was used at a 5% level of statistical significance.
  
  
  RESULTS
  A statistically significant inverse association was found between pancreatic cancer and oral contraceptives (OR 0.21; 95% CI: 0.07-0.69). Pregnancy and number of pregnancies or gynecological surgical procedures did not show any association with pancreatic cancer. No significant difference in the first menstrual period was found between pancreatic cancer patients and controls.
  
  
  CONCLUSIONS
  The study results showed inverse association between pancreatic cancer and oral contraceptives (OR 0.21; 95% CI: 0.07-0.69), controlled alcohol consumption (OR 0.26; 95% CI: 0.12-0.55), and anti-inflamatory drug use (OR 0.10; 95% CI: 0.02-0.41).
authors: K
authors: K
authors: Azeem
authors: D
authors: D
authors: Horáková
authors: H
authors: H
authors: Tomášková
authors: J
authors: J
authors: Ševčíková
authors: J
authors: J
authors: Vlčková
authors: D
authors: D
authors: Pastucha
authors: V
authors: V
authors: Procházka
authors: O
authors: O
authors: Shonová
authors: A
authors: A
authors: Martínek
authors: V
authors: V
authors: Janout
authors: V
authors: V
authors: Žídková
authors: H
authors: H
authors: Kollárová
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003276:Contraceptives, Oral / Q000008:administration & dosage; D018153:Czech Republic / Q000453:epidemiology; D005260:Female; D006801:Humans; D008572:Menarche; D008875:Middle Aged; D016017:Odds Ratio; D010190:Pancreatic Neoplasms / Q000453:epidemiology / Q000209:etiology*; D011247:Pregnancy; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D003276:Contraceptives, Oral
keywords: pancreatic cancer - risk factor - multifactor analysis - odds ratio.