title: An intramolecular crossed-benzoin reaction based KCN fluorescent probe in aqueous and biological environments.
abstract: A turn-on fluorescent probe was designed for selective cyanide anion sensing in aqueous and biological environments. The probe underwent an intramolecular crossed-benzoin reaction in the presence of KCN to expel the fluorophore resorufin. This probe was sensitive to KCN concentrations as low as 4 nM in aqueous media.
authors: Department of Chemistry, Korea University, Seoul 136-701, Korea. jongskim@korea.ac.kr.
authors: Jae Hong
authors: JH
authors: Lee
authors: Joo Hee
authors: JH
authors: Jang
authors: Nithya
authors: N
authors: Velusamy
authors: Hyo Sung
authors: HS
authors: Jung
authors: Sankarprasad
authors: S
authors: Bhuniya
authors: Jong Seung
authors: JS
authors: Kim
mesh_terms: D000838:Anions / Q000032:analysis; D001573:Benzoin / Q000737:chemistry*; D003486:Cyanides / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D018613:Microscopy, Confocal; D015394:Molecular Structure; D010078:Oxazines / Q000737:chemistry; D011190:Potassium Cyanide / Q000032:analysis*; D013050:Spectrometry, Fluorescence; D014867:Water / Q000737:chemistry
chemical_list: D000838:Anions; D003486:Cyanides; D005456:Fluorescent Dyes; D010078:Oxazines; D014867:Water; C014180:resorufin; D001573:Benzoin; D011190:Potassium Cyanide