title: Chemical compositions and antibacterial activity of extracts obtained from the inflorescences of Cirsium canum (L.) all.
abstract: The aim of this study was to investigate phenolic acids and flavonoids in methanolic, dichloromethane, acetone and ethyl acetate extracts and fractions from inflorescences of Cirsium canum (L.). RP-HPLC analysis enabled identification of the following: chlorogenic acid, caffeic acid, p-coumaric acid, protocatechuic acid, p-hydroxybenzoic acid, vanillic acid, syringic acid, trans-cinnamic acid, luteolin-7-glucoside, apigenin-7-glucoside, kaempferol-3-glucoside, linarin, apigenin, rutoside, luteolin and kaempferol. The antimicrobial activity of tested extracts was determined in vitro against reference microorganisms, including bacteria or fungi, belonging to yeasts. Our data showed that the tested extracts had no influence on the growth of the reference strains of Gram-negative bacteria and yeasts belonging to Candida spp. Among them, the fractions possessed the highest activity against Gram-positive bacteria, especially Streptococcus aureus and Streptococcus pneumoniae belonging to pathogens and Streptococcus epidermidis, Bacilluscereus and Bacillus subtilis belonging to opportunistic microorganisms.
authors: a Chair and Department of Pharmacognosy with Medicinal Plant Laboratory , Medical University , 1 Chodźki Street, 20-093, Lublin , Poland.
authors: Małgorzata
authors: M
authors: Kozyra
authors: Anna
authors: A
authors: Biernasiuk
authors: Anna
authors: A
authors: Malm
authors: Marcin
authors: M
authors: Chowaniec
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification; D001407:Bacillus / Q000187:drug effects; D031180:Cirsium / Q000737:chemistry*; D056626:Inflorescence / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D064209:Phytochemicals / Q000737:chemistry / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry*; D013291:Streptococcus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D064209:Phytochemicals; D010936:Plant Extracts
keywords: Cirsium canum (L.) All; antibacterial activity; flavonoids; phenolic acids