title: Synthesis of silver nanoparticle and its application.
abstract: In this work, silver nanoparticles have been synthesized by wet chemical technique, green synthesis and microbial methods. Silver nitrate (10(-3)M) was used with aqueous extract to produce silver nanoparticles. From the results it was observed that the yield of nanoparticles was high in green synthesis. The size of the silver nanoparticles was determined from Scanning Electron Microscope analysis (SEM). Fourier Transform Infrared spectroscopy (FTIR) was carried out to determine the presence of biomolecules in them. Its cytotoxic effect was studied in cancerous cell line and normal cell line. MTT assay was done to test its optimal concentration and efficacy which gives valuable information for the use of silver nanoparticles for future cancer therapy.
authors: Environmental Engineering Laboratory, Department of Chemical Engineering, Annamalai University, Annamalai Nagar, Tamil Nadu, India. Electronic address: mkp.asokan@gmail.com.
authors: A Muthu Kumara
authors: AM
authors: Pandian
authors: Environmental Engineering Laboratory, Department of Chemical Engineering, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
authors: C
authors: C
authors: Karthikeyan
authors: Environmental Engineering Laboratory, Department of Chemical Engineering, Annamalai University, Annamalai Nagar, Tamil Nadu, India.
authors: M
authors: M
authors: Rajasimman
authors: Department of Ayurvedic and Siddha medicine, Sriramachandra Medical College, Chennai, Tamil Nadu, India.
authors: M G
authors: MG
authors: Dinesh
mesh_terms: D017209:Apoptosis / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005737:Garlic / Q000737:chemistry; D056945:Hep G2 Cells; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D036103:Nanotechnology / Q000379:methods*; D010316:Particle Size; D010936:Plant Extracts / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D012834:Silver / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D012835:Silver Nitrate / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties
chemical_list: D010936:Plant Extracts; D012834:Silver; D012835:Silver Nitrate
keywords: Aillum sativum; Cytotoxicity; Green synthesis; Nanotechnology