title: Somatosensory evoked potentials and blood lactate levels.
abstract: We compared, in 20 subjects, the effects of high blood lactate levels on amplitude and latency of P1, N1, P2 and N2 components of lower limb somatosensory evoked potential (SEP), an useful, noninvasive tool for assessing the transmission of the afferent volley from periphery up to the cortex. SEPs were recorded from CPz located over the somatosensory vertex and referenced to FPz with a clavicle ground. Measurements were carried out before, at the end as well as 10 and 20 min after the conclusion of a maximal exercise carried out on a mechanically braked cycloergometer. After the exercise, P2-N2 amplitudes as well as latency of P1 and N1 components showed small but significant reductions. On the contrary, latency of N2 component exhibited a significant increase after the exercise's conclusion. These results suggest that blood lactate appears to have a protective effect against fatigue, at least at level of primary somatosensory cortex, although at the expense of efficiency of adjacent areas.
authors: Department of Sciences of Formation, University of Catania, Catania, Italy.
authors: Valentina
authors: V
authors: Perciavalle
authors: Giovanna
authors: G
authors: Alagona
authors: Giulia
authors: G
authors: De Maria
authors: Giuseppe
authors: G
authors: Rapisarda
authors: Erminio
authors: E
authors: Costanzo
authors: Vincenzo
authors: V
authors: Perciavalle
authors: Marinella
authors: M
authors: Coco
mesh_terms: D000328:Adult; D001642:Bicycling / Q000502:physiology; D001774:Blood Chemical Analysis; D005073:Evoked Potentials, Somatosensory; D015444:Exercise; D005260:Female; D006801:Humans; D019344:Lactic Acid / Q000097:blood*; D035002:Lower Extremity / Q000502:physiology*; D008297:Male; D018763:Muscle Fatigue; D013003:Somatosensory Cortex / Q000502:physiology*; D013979:Tibial Nerve / Q000502:physiology; D055815:Young Adult
chemical_list: D019344:Lactic Acid