title: [In vivo "editing'' of cellular genome: one more step toward animals models mimicking tumorigenesis].
authors: Christian-Jacques
authors: CJ
authors: Larsen
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D000077548:Anaplastic Lymphoma Kinase; D000818:Animals; D064113:CRISPR-Cas Systems; D002289:Carcinoma, Non-Small-Cell Lung / Q000235:genetics* / Q000473:pathology; D007446:Chromosome Inversion / Q000235:genetics*; D000077547:Crizotinib; D004195:Disease Models, Animal; D018014:Gene Transfer Techniques; D011905:Genes, ras; D056914:Genomic Structural Variation; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D051379:Mice; D041681:NIH 3T3 Cells; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D010766:Phosphorylation; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use; D011720:Pyrazoles / Q000627:therapeutic use; D011725:Pyridines / Q000627:therapeutic use; D017393:RNA Editing; D020794:Receptor Protein-Tyrosine Kinases / Q000187:drug effects / Q000235:genetics; D014178:Translocation, Genetic
chemical_list: C501947:EML1-ABL1 fusion protein, human; C522504:EML4-ALK fusion protein, human; D015514:Oncogene Proteins, Fusion; D047428:Protein Kinase Inhibitors; D011720:Pyrazoles; D011725:Pyridines; D000077547:Crizotinib; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases