title: Suspected nosocomial infections with multi-drug resistant E. coli, including extended-spectrum beta-lactamase (ESBL)-producing strains, in an equine clinic.
abstract: Enterobacteriaceae such as Escherichia coli are common commensals as well as opportunistic and obligate pathogens. They cause a broad spectrum of infectious diseases in various hosts, including hospital-associated infections. In recent years, the rise of extended spectrum beta-lactamase (ESBL)-producing E. coli in companion animals (dogs, cats and horses) has been striking. However, reports on nosocomial infections are mostly anecdotic. Here we report on the suspected nosocomial spread of both ESBL-producing and non-ESBL-producing multi-drug resistant E. coli isolates in three equine patients within an equine clinic. Unlike easy-to-clean hospitalization opportunities available for small animal settings like boxes and cages made of ceramic floor tiles or stainless steel, clinical settings for horses are challenging environments for infection control programs due to unavoidable extraneous material including at least hay and materials used for horse bedding. The development of practice-orientated recommendations is needed to improve the possibilities for infection control to prevent nosocomial infections with multi-drug resistant and other transmissible pathogens in equine clinical settings.
authors: Birgit
authors: B
authors: Walther
authors: Antina
authors: A
authors: Lübke-Becker
authors: Ivonne
authors: I
authors: Stamm
authors: Heidrun
authors: H
authors: Gehlen
authors: Ann Kristin
authors: AK
authors: Barton
authors: Traute
authors: T
authors: Janssen
authors: Lothar H
authors: LH
authors: Wieler
authors: Sebastian
authors: S
authors: Guenther
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003428:Cross Infection / Q000382:microbiology / Q000662:veterinary*; D024901:Drug Resistance, Multiple, Bacterial; D004783:Environmental Microbiology; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000382:microbiology / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000382:microbiology*; D006736:Horses; D006762:Hospitals, Animal; D008297:Male; D008826:Microbial Sensitivity Tests; D012189:Retrospective Studies; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases