title: Inhibitory control in otherwise healthy overweight 10-year-old children.
abstract: BACKGROUND
  Preventing obesity is a worldwide public health priority. In vulnerable children living in obesogenic environments, with easy access to high-caloric food, alterations in inhibitory control functions might favor excessive food intake and affect energy regulation. We hypothesized that overweight/obese children would present lower inhibitory control in comparison to normal weight children.
  
  
  METHODS
  We measured inhibitory control functions in 93 otherwise healthy overweight/obese and 92 normal weight 10-year-old children using the Stroop test and the Go/No-Go task. Event-related potentials were recorded during the Go/No-Go task.
  
  
  RESULTS
  Overweight/obese children showed slower reaction times (1248.6 ms (95% confidence interval (CI): 1182.9-1314.3) vs 1149.0 ms (95% CI: 1083.0-1215.1)) on the Stroop test, higher reaction time variability (0.25 (95% CI: 0.22-0.27) vs 0.21 (95% CI: 0.19-0.24)) on the Go/No-Go task and decreased P300 amplitude (4.1 μV (95% CI: 3.0-5.2) vs 6.4 μV (95% CI: 5.2-7.6)) on event-related potentials compared with normal weight children.
  
  
  CONCLUSIONS
  Our results indicate altered inhibitory control functions in otherwise healthy overweight/obese children, which might contribute to their excessive food consumption.
authors: Sleep and Functional Neurobiology Laboratory, Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.
authors: S
authors: S
authors: Reyes
authors: Sleep and Functional Neurobiology Laboratory, Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.
authors: P
authors: P
authors: Peirano
authors: UR2NF-Neuropsychology and Functional Neuroimaging Research Unit at CRCN-Centre de Recherches en Cognition et Neurosciences and UNI, Neurosciences Institute, Université Libre de Bruxelles (ULB), Belgium.
authors: P
authors: P
authors: Peigneux
authors: Center for Human Growth and Development and Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA.
authors: B
authors: B
authors: Lozoff
authors: Sleep and Functional Neurobiology Laboratory, Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.
authors: C
authors: C
authors: Algarin
mesh_terms: D015992:Body Mass Index; D002648:Child; D002677:Chile / Q000453:epidemiology; D003072:Cognition Disorders / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D004569:Electroencephalography; D005071:Evoked Potentials; D056344:Executive Function; D005260:Female; D006801:Humans; D007266:Inhibition, Psychological; D008137:Longitudinal Studies; D008297:Male; D009483:Neuropsychological Tests; D050177:Overweight / Q000453:epidemiology / Q000503:physiopathology* / Q000523:psychology; D011930:Reaction Time