title: Thrombocytopenia associated with Mycoplasma pneumonia during pregnancy: case presentation and approach for differential diagnosis.
abstract: Thrombocytopenia during pregnancy has many different causes, but Mycoplasma pneumoniae is not usually considered one of the several pathogens that induce thrombocytopenia. Herein, we present a case of severe thrombocytopenia that was associated with M. pneumoniae during pregnancy. The patient experienced fever, cough, and cytopenia with M. pneumoniae-specific IgM antibody increasing from 40-fold to 160-fold during the 2 weeks of illness. A diagnosis was made after excluding other diseases that cause thrombocytopenia. The patient was successfully treated with azithromycin hydrate, and she delivered a healthy newborn without any complications. Pregnant women who are infected with M. pneumoniae during pregnancy may develop severe and fatal thrombocytopenia. Prompt diagnosis and initiation of treatment lead to early recovery.
authors: Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors: Aiko
authors: A
authors: Nishikawa
authors: Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors: Kazuya
authors: K
authors: Mimura
authors: Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors: Takeshi
authors: T
authors: Kanagawa
authors: Hematology and Oncology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors: Tetsuo
authors: T
authors: Maeda
authors: Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors: Takuji
authors: T
authors: Tomimatsu
authors: Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors: Tadashi
authors: T
authors: Kimura
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D011019:Pneumonia, Mycoplasma / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013921:Thrombocytopenia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
keywords: Mycoplasma pneumoniae; hemophagocytic lymphohistiocytosis; immune; pregnancy; thrombocytopenia