title: [Yhe pre-analytic stage in studies of surveillance of HIV strains resistant to anti-retrovirus preparations in the Privolzhskiy Federal Okrug].
abstract: The article presents analysis of activities concerning organization of pre-analytic stage of monitoring of HIV resistance to anti- retrovirus preparations on territories of the Privolzhskiy Federal Okrug. The medical records of patients receiving anti-retrovirus therapy and appointment cards to detect drug resistance of HIV from territorial centers of prevention and control of AIDS and infectious diseases are analyzed. The results of testing of specialists of service of prevention of AIDS/HIV with questionnaire "Characteristics of pre-analytical stage under implementation of molecular genetic and immunologic analyses" developed in the Privolzhskiy okrug center of prevention and control ofAIDS and samples of bio-tests obtained during coming-outs in regions of okrug were included into analysis too. The failures in implementation of pre-analytical stage were established. Hence, the subsequent decreasing of informativeness of analyses or inexpediency or even impossibility of application of testing of AIDS drug resistance. The recommendations are proposed concerning main directions of work to enhance pre-analytical stage of analysis of AIDS resistance to anti-retrovirus preparations.
authors: N N
authors: NN
authors: Zaĭtseva
authors: N I
authors: NI
authors: Ivanova
authors: O V
authors: OV
authors: Parfenova
authors: N N
authors: NN
authors: Nosov
authors: O Iu
authors: OIu
authors: Peksheva
authors: E E
authors: EE
authors: Al'tova
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy / Q000453:epidemiology* / Q000821:virology; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D024882:Drug Resistance, Viral / Q000235:genetics*; D006678:HIV / Q000187:drug effects* / Q000235:genetics; D006801:Humans; D012426:Russia
chemical_list: D018501:Antirheumatic Agents