title: Fortified versus incurred residues: extraction of furazolidinone metabolite from prawn.
abstract: Most methods reported in the literature for determination of nitrofuran metabolites use the same extraction and derivatisation conditions to hydrolyse and extract the protein-bound residues from animal tissue. While undertaking certification of reference materials for nitrofuran metabolites in freeze-dried prawn, it was found that these conditions are satisfactory for recovery of spiked residues; however, extraction efficiencies of incurred furazolidinone could be substantially increased by further optimisation of the extraction conditions. The availability of a suitable certified reference material allows laboratories to ensure that their method is optimised for incurred residues.
authors: National Measurement Institute Australia, 105 Delhi Rd, North Ryde, NSW, 2113, Australia, lesley.johnston@measurement.gov.au.
authors: Lesley
authors: L
authors: Johnston
authors: Meg
authors: M
authors: Croft
authors: John
authors: J
authors: Murby
mesh_terms: D000818:Animals; D002853:Chromatography, Liquid; D003445:Crustacea / Q000737:chemistry*; D004350:Drug Residues / Q000032:analysis / Q000302:isolation & purification*; D009581:Nitrofurans / Q000032:analysis / Q000302:isolation & purification*; D053719:Tandem Mass Spectrometry
chemical_list: D009581:Nitrofurans