title: Current neurological observations and complications of dengue virus infection.
abstract: Dengue, a mosquito-borne flavivirus and fastest growing tropical disease in the world, has experienced an explosion of neurologic case reports and series in recent years. Now dengue is a frequent or leading cause of encephalitis in some endemic regions, is estimated to infect one in six tourists returning from the tropics, and has been proven to have local transmission within the continental USA. High documentation of neurologic disease in recent years reflects increases in overall cases, enhanced clinical awareness and advances in diagnostics. Neurological aspects of dengue virus, along with epidemiology, treatment, and vaccine progress, are presented.
authors: Department of Pharmacology and Toxicology, School of Pharmacy, University of Kansas, 1251 Wescoe Hall Drive, Malott Hall Rm 5040, Lawrence, KS, 66045, USA, msolbrig3@ku.edu.
authors: Marylou V
authors: MV
authors: Solbrig
authors: Guey-Chuen
authors: GC
authors: Perng
mesh_terms: D003715:Dengue / Q000150:complications*; D003716:Dengue Virus; D006801:Humans; D064789:Immunity, Heterologous; D009422:Nervous System Diseases / Q000209:etiology* / Q000517:prevention & control / Q000628:therapy; D016896:Treatment Outcome