title: Mutagenic and carcinogenic actions of chromium and its compounds.
abstract: Numerous experimental observations have been made on microorganisms and culture of the cells of mammals as well as the accounting of the chromosomal aberrations in the bone marrow cells of the mammals and of human cells displayed that the chromium and its compounds possess a pronounced mutagenic effect. Translocation test, induction record of DNA damage and repair systems in the mammalian and human cells with greater precision proves the presence of the mutagenic effect of the chromium and its compounds, which in turn is dependent on dose and time of this metal intoxication. Chromium and its compounds have pronounced mutagenic effect, on increased admission to organism of mammals and protozoa.
authors: West-Kazakhstan State Medical University Named After Marat Ospanov, Maresyev street 68, 030019, Aktobe City, The Republic of Kazakhstan, asemaika@mail.ru.
authors: Arstan Abdramanovich
authors: AA
authors: Mamyrbaev
authors: Timur Agataevich
authors: TA
authors: Dzharkenov
authors: Zina Amangalievna
authors: ZA
authors: Imangazina
authors: Umit Abulkhairovna
authors: UA
authors: Satybaldieva
mesh_terms: D000818:Animals; D001419:Bacteria / Q000187:drug effects; D002273:Carcinogens / Q000633:toxicity*; D002470:Cell Survival / Q000187:drug effects; D002857:Chromium / Q000633:toxicity*; D017608:Chromium Compounds / Q000633:toxicity*; D004247:DNA / Q000187:drug effects; D006801:Humans; D007448:Invertebrates / Q000187:drug effects; D009153:Mutagens / Q000633:toxicity*; D014714:Vertebrates / Q000378:metabolism
chemical_list: D002273:Carcinogens; D017608:Chromium Compounds; D009153:Mutagens; D002857:Chromium; D004247:DNA