title: Synthesis of Biofunctional Janus Particles.
abstract: Janus particles with anisotropic biofunctionalities are perfect models to mimic anisotropic architectures and directional interactions that occur in nature. It is therefore highly desirable to develop reliable and efficient methods to synthesize biofunctional Janus particles. Herein, a facile method combining seeded-emulsion polymerization and thiol-click chemistry has been developed to synthesize Janus particles with glucose moieties on one side. These biofunctional Janus particles show region-selective binding of protein, which represents a big step toward biomimicry, and demonstrates the potential of the bioJanus particles for targeted drug delivery and binding.
authors: Center for Soft Condensed Matter Physics and Interdisciplinary Research & Collaborative Innovation Center of Suzhou Nano Science and Technologyand College of Physics, Optoelectronics and Energy, Soochow University, Suzhou, 215006, China.
authors: Binghui
authors: B
authors: Li
authors: Center for Soft Condensed Matter Physics and Interdisciplinary Research & Collaborative Innovation Center of Suzhou Nano Science and Technologyand College of Physics, Optoelectronics and Energy, Soochow University, Suzhou, 215006, China.
authors: Man
authors: M
authors: Wang
authors: Center for Soft Condensed Matter Physics and Interdisciplinary Research & Collaborative Innovation Center of Suzhou Nano Science and Technologyand College of Physics, Optoelectronics and Energy, Soochow University, Suzhou, 215006, China.
authors: Kui
authors: K
authors: Chen
authors: Center for Soft Condensed Matter Physics and Interdisciplinary Research & Collaborative Innovation Center of Suzhou Nano Science and Technologyand College of Physics, Optoelectronics and Energy, Soochow University, Suzhou, 215006, China.
authors: Zhifeng
authors: Z
authors: Cheng
authors: Center for Soft Condensed Matter Physics and Interdisciplinary Research & Collaborative Innovation Center of Suzhou Nano Science and Technologyand College of Physics, Optoelectronics and Energy, Soochow University, Suzhou, 215006, China.
authors: Gaojian
authors: G
authors: Chen
authors: Center for Soft Condensed Matter Physics and Interdisciplinary Research & Collaborative Innovation Center of Suzhou Nano Science and Technologyand College of Physics, Optoelectronics and Energy, Soochow University, Suzhou, 215006, China.
authors: Zexin
authors: Z
authors: Zhang
mesh_terms: D001391:Azo Compounds / Q000737:chemistry*; D057930:Click Chemistry; D011137:Polystyrenes / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D001391:Azo Compounds; D011137:Polystyrenes
keywords: Janus particles; biobinding; colloids; emulsion polymerization; glucose; thoil-click chemistry