title: Comparison between PRP, PRGF and PRF: lights and shadows in three similar but different protocols.
abstract: OBJECTIVE
  The main goal of the modern surgery is to get a low invasiveness and a high rate of clinical healing: in the last years, it has been introduced the concept of a "regenerative surgery", and many techniques has been widely described in the literature. The most used are PRP, PRGF and PRF techniques. Aim of this research is to compare the three protocol of PRP, PRF and PRGF in their essential features, so to suggest to the practitioners the best blood product to use in the regenerative surgery.
  
  
  CONCLUSIONS
  Among the advantages that shows the PRF, compared to PRP and PRGF, we can cite a greater simplicity of production for the absence of manipulation that leads to a reduced possibility of alteration of the protocol due to an error of the operator. The special texture of the PRF and its biological features shows clearly an interesting surgical versatility and all the characteristics that can support a faster tissues regeneration and high-quality clinical outcomes.
authors: Private Practice, Rome, Italy. ricercadentale@libero.it.
authors: S
authors: S
authors: Giannini
authors: A
authors: A
authors: Cielo
authors: L
authors: L
authors: Bonanome
authors: C
authors: C
authors: Rastelli
authors: C
authors: C
authors: Derla
authors: F
authors: F
authors: Corpaci
authors: G
authors: G
authors: Falisi
mesh_terms: D005337:Fibrin / Q000008:administration & dosage*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage*; D053657:Platelet-Rich Plasma / Q000502:physiology*; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology*
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; D005337:Fibrin