title: Introduction of 2-octyl cyanoacrylate (Dermabond®) for incisional hernia mesh repair.
abstract: OBJECTIVE
  We developed a new technique, sutureless mesh fixation, using 2-octyl cyanoacrylate (Dermabond®, a surgical tissue adhesive) for incisional hernia repair. The objective of this article is to introduce the new technique and to examine whether the technique provides sufficient resistance to abdominal pressure.
  
  
  METHODS
  We conducted two tests using a porcine model, a traction experiment and artificial pneumoperitoneum test. In the traction experiment, the adherence properties of Dermabond®with mesh and peritoneum were examined using a tissue fragment from a pig. In the artificial pneumoperitoneum test, which used an incisional hernia porcine model, mesh was implanted on the peritoneum in the abdominal cavity with Dermabond®. It was then determined whether sutureless mesh fixation could bear artificial abdominal air pressure.
  
  
  RESULTS
  In the traction experiment, Dermabond®, which bonded the mesh to the peritoneum, tolerated pressure up to 2.45 × 103mmHg. In the artificial pneumoperitoneum test, the mesh was strongly fastened to the peritoneum by means of only Dermabond®, and there was little air circulation even without closing the wound over the mesh.
  
  
  CONCLUSIONS
  Sutureless mesh fixation with Dermabond®is technically feasible and promises to provide sufficient resistance to abdominal pressure.
authors: Department of Surgery Gastroenterology Center, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-ku, Tokyo, 108-8329, Japan. yoshiyuksaito@gmail.com.
authors: Yoshiyuki
authors: Y
authors: Saito
authors: Department of Surgery, St. Luke's International Hospital, 9-1, Akashi-cho, Chuo City, Tokyo, 104-8560, Japan.
authors: Keisuke
authors: K
authors: Kubota
authors: Department of Surgery Gastroenterology Center, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-ku, Tokyo, 108-8329, Japan.
authors: Akihiro
authors: A
authors: Okada
authors: Department of Surgery Gastroenterology Center, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-ku, Tokyo, 108-8329, Japan.
authors: Tomoaki
authors: T
authors: Deguchi
authors: Department of Surgery Gastroenterology Center, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-ku, Tokyo, 108-8329, Japan.
authors: Junko
authors: J
authors: Kuroda
authors: Department of Surgery Gastroenterology Center, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-ku, Tokyo, 108-8329, Japan.
authors: Nobuhiro
authors: N
authors: Nitori
authors: Department of Surgery Gastroenterology Center, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-ku, Tokyo, 108-8329, Japan.
authors: Tomohisa
authors: T
authors: Kadomura
authors: Department of Surgery Gastroenterology Center, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-ku, Tokyo, 108-8329, Japan.
authors: Masashi
authors: M
authors: Yoshida
authors: Department of Surgery Gastroenterology Center, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-ku, Tokyo, 108-8329, Japan.
authors: Masaki
authors: M
authors: Kitajima
keywords: 2-Octyl cyanoacrylate; Postoperative pain; Sutureless mesh fixation; Ventral hernia