title: Para testicular rhabdomyosarcoma in adults: three case reports and review of literature.
abstract: Paratesticular embryonal rhabdomyosarcoma (RMS) is a rare tumor arising from the mesenchymal tissues of the spermatic cord, epididymis, testis and testicular tunics. We report three cases of adult paratesticular RMS, two embryonic and one pleomorphic rhabdomyosarcoma. All the patients underwent diagnostic orchidectomy. The work up investigations revealed lung metastases. Chemotherapy with Ifosfamide and Doxorubicin was used in two cases, whereas Vincristin-Actinomycin D and Cyclophosphamide was received in one case. An objective partial response was reported in 2 cases, with complete response in one case. Paratesticular RMS is a rare and aggressive tumor. Because of the absence of protocols designed specifically for adult patients, it is necessary to follow therapeutic guidelines in pediatric protocols.
authors: Medical Oncology Department, Hassan II University Hospital, Fez, Morocco.
authors: Lamiae
authors: L
authors: Boudahna
authors: Medical Oncology Department, Hassan II University Hospital, Fez, Morocco.
authors: Zineb
authors: Z
authors: Benbrahim
authors: Medical Oncology Department, Hassan II University Hospital, Fez, Morocco.
authors: Lamiae
authors: L
authors: Amaadour
authors: Medical Oncology Department, Hassan II University Hospital, Fez, Morocco.
authors: Aicha
authors: A
authors: Mazouz
authors: Laboratory of Pathology, Hassan II University Hospital, Fez, Morocco.
authors: Khadija
authors: K
authors: Benhayoune
authors: Urology department, Hassan II University Hospital, Fez, Morocco.
authors: Yassir
authors: Y
authors: Tahiri
authors: Urology department, Hassan II University Hospital, Fez, Morocco.
authors: Moulay Hassan
authors: MH
authors: Farih
authors: Laboratory of Pathology, Hassan II University Hospital, Fez, Morocco.
authors: Afaf
authors: A
authors: Amarti
authors: Medical Oncology Department, Hassan II University Hospital, Fez, Morocco.
authors: Samia
authors: S
authors: Arifi
authors: Medical Oncology Department, Hassan II University Hospital, Fez, Morocco.
authors: Nawfel
authors: N
authors: Mellas
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009919:Orchiectomy / Q000379:methods; D017410:Practice Guidelines as Topic; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome; D055815:Young Adult
keywords: Para testicular rhabdomyosarcoma; adults; tumor