title: Non-targeted metabolomics and lipidomics LC-MS data from maternal plasma of 180 healthy pregnant women.
abstract: BACKGROUND
  Metabolomics has the potential to be a powerful and sensitive approach for investigating the low molecular weight metabolite profiles present in maternal fluids and their role in pregnancy.
  
  
  RESULTS
  In this Data Note, LC-MS metabolome, lipidome and carnitine profiling data were collected from 180 healthy pregnant women, representing six time points spanning all three trimesters, and providing sufficient coverage to model the progression of normal pregnancy.
  
  
  CONCLUSIONS
  As a relatively large scale, real-world dataset with robust numbers of quality control samples, the data are expected to prove useful for algorithm optimization and development, with the potential to augment studies into abnormal pregnancy. All data and ISA-TAB format enriched metadata are available for download in the MetaboLights and GigaScience databases.
authors: Department of Chemistry, Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong China ; BGI-Shenzhen, Building No.11, Beishan Industrial Zone, Yantian District, Shenzhen 518083 China.
authors: Hemi
authors: H
authors: Luan
authors: BGI-Shenzhen, Building No.11, Beishan Industrial Zone, Yantian District, Shenzhen 518083 China.
authors: Nan
authors: N
authors: Meng
authors: BGI-Shenzhen, Building No.11, Beishan Industrial Zone, Yantian District, Shenzhen 518083 China.
authors: Ping
authors: P
authors: Liu
authors: BGI-Shenzhen, Building No.11, Beishan Industrial Zone, Yantian District, Shenzhen 518083 China.
authors: Jin
authors: J
authors: Fu
authors: BGI-Shenzhen, Building No.11, Beishan Industrial Zone, Yantian District, Shenzhen 518083 China.
authors: Xiaomin
authors: X
authors: Chen
authors: BGI-Shenzhen, Building No.11, Beishan Industrial Zone, Yantian District, Shenzhen 518083 China.
authors: Weiqiao
authors: W
authors: Rao
authors: BGI-Shenzhen, Building No.11, Beishan Industrial Zone, Yantian District, Shenzhen 518083 China.
authors: Hui
authors: H
authors: Jiang
authors: BGI-Shenzhen, Building No.11, Beishan Industrial Zone, Yantian District, Shenzhen 518083 China.
authors: Xun
authors: X
authors: Xu
authors: Department of Chemistry, Hong Kong Baptist University, 224 Waterloo Road, Kowloon Tong, Hong Kong China.
authors: Zongwei
authors: Z
authors: Cai
authors: BGI-Shenzhen, Building No.11, Beishan Industrial Zone, Yantian District, Shenzhen 518083 China ; Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen, Denmark.
authors: Jun
authors: J
authors: Wang
mesh_terms: D002331:Carnitine / Q000097:blood; D002853:Chromatography, Liquid; D005260:Female; D006801:Humans; D050356:Lipid Metabolism; D013058:Mass Spectrometry; D055432:Metabolomics; D010949:Plasma / Q000378:metabolism*; D011247:Pregnancy / Q000097:blood / Q000378:metabolism*; D011261:Pregnancy Trimester, First / Q000097:blood / Q000378:metabolism; D011262:Pregnancy Trimester, Second / Q000097:blood / Q000378:metabolism; D011263:Pregnancy Trimester, Third / Q000097:blood / Q000378:metabolism
chemical_list: D002331:Carnitine
keywords: Lipidomics; Maternal plasma; Metabolic phenotype; Metabolomics; Pregnancy