title: Primary synovial cell sarcoma of the kidney: case report and review of the literature.
abstract: Synovial cell sarcoma (SCS) of the kidney is a rare tumor entity with a poor prognosis. Morphologic and immunohistochemical characteristics may overlap with other more common neoplasms of the kidney. Therefore, the diagnosis of primary renal SCS not only requires the exclusion of similar tumor types, but also a confirmation of SYT-SSX gene fusion using molecular techniques. The treatment comprises radical surgery, and, depending on age and health status, adjuvant chemotherapy in selected patients. Here, we present an elderly SCS patient in whom straightforward radical surgical treatment resulted in a sustained complete remission; it allowed us to perform a literature survey focusing on current diagnostic tools for SCS.
authors: Department of Urology, St. Claraspital, Basel, Switzerland.
authors: Marc
authors: M
authors: Vedana
authors: Institute of Pathology, University Hospital, Basel, Switzerland.
authors: Maya
authors: M
authors: Fuenfschilling
authors: Institute of Pathology, University Hospital, Basel, Switzerland.
authors: Alexandar
authors: A
authors: Tzankov
authors: Department of Urology, St. Claraspital, Basel, Switzerland.
authors: Tobias
authors: T
authors: Zellweger
keywords: Renal spindle cell tumor; Renal synovial cell sarcoma; SYT gene rearrangement; SYT-SSX gene fusion; Transducin-like enhancer of split 1