title: Lung function and respiratory diseases in people with psychosis: population-based study.
abstract: BACKGROUND
  There is little information on lung function and respiratory diseases in people with psychosis.
  
  
  OBJECTIVE
  To compare the respiratory health of people with psychosis with that of the general population.
  
  
  METHODS
  In a nationally representative sample of 8028 adult Finns, lung function was measured by spirometry. Information on respiratory diseases and symptoms was collected. Smoking was quantified with serum cotinine levels. Psychotic disorders were diagnosed utilising the Structured Clinical Interview for DSM-IV (SCID-I) and medical records.
  
  
  RESULTS
  Participants with schizophrenia and other non-affective psychoses had significantly lower lung function values compared with the general population, and the association remained significant for schizophrenia after adjustment for smoking and other potential confounders. Schizophrenia was associated with increased odds of pneumonia (odds ratio (OR) = 4.9), chronic obstructive pulmonary disease (COPD, OR = 4.2) and chronic bronchitis (OR = 3.8); and with high cotinine levels.
  
  
  CONCLUSIONS
  Schizophrenia is associated with impaired lung function and increased risk for pneumonia, COPD and chronic bronchitis.
authors: Krista Partti, MD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki, Finland; Tuula Vasankari, MD, PhD, Finnish Lung Health Association, Helsinki, Finland; Merja Kanervisto, PhD, School of Health Sciences, University of Tampere, Finland; Jonna Perälä, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, and Department of Psychiatry, Helsinki University Central Hospital, Finland; Samuli I. Saarni, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Hospital District of Southwest Finland, Turku, Finland; Pekka Jousilahti, MD, PhD, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Jouko Lönnqvist, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki and Helsinki University Central Hospital, Finland; Jaana Suvisaari, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Tampere School of Public Health, University of Tampere, Finland krista.partti@thl.fi.
authors: Krista
authors: K
authors: Partti
authors: Krista Partti, MD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki, Finland; Tuula Vasankari, MD, PhD, Finnish Lung Health Association, Helsinki, Finland; Merja Kanervisto, PhD, School of Health Sciences, University of Tampere, Finland; Jonna Perälä, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, and Department of Psychiatry, Helsinki University Central Hospital, Finland; Samuli I. Saarni, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Hospital District of Southwest Finland, Turku, Finland; Pekka Jousilahti, MD, PhD, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Jouko Lönnqvist, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki and Helsinki University Central Hospital, Finland; Jaana Suvisaari, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Tampere School of Public Health, University of Tampere, Finland.
authors: Tuula
authors: T
authors: Vasankari
authors: Krista Partti, MD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki, Finland; Tuula Vasankari, MD, PhD, Finnish Lung Health Association, Helsinki, Finland; Merja Kanervisto, PhD, School of Health Sciences, University of Tampere, Finland; Jonna Perälä, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, and Department of Psychiatry, Helsinki University Central Hospital, Finland; Samuli I. Saarni, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Hospital District of Southwest Finland, Turku, Finland; Pekka Jousilahti, MD, PhD, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Jouko Lönnqvist, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki and Helsinki University Central Hospital, Finland; Jaana Suvisaari, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Tampere School of Public Health, University of Tampere, Finland.
authors: Merja
authors: M
authors: Kanervisto
authors: Krista Partti, MD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki, Finland; Tuula Vasankari, MD, PhD, Finnish Lung Health Association, Helsinki, Finland; Merja Kanervisto, PhD, School of Health Sciences, University of Tampere, Finland; Jonna Perälä, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, and Department of Psychiatry, Helsinki University Central Hospital, Finland; Samuli I. Saarni, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Hospital District of Southwest Finland, Turku, Finland; Pekka Jousilahti, MD, PhD, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Jouko Lönnqvist, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki and Helsinki University Central Hospital, Finland; Jaana Suvisaari, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Tampere School of Public Health, University of Tampere, Finland.
authors: Jonna
authors: J
authors: Perälä
authors: Krista Partti, MD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki, Finland; Tuula Vasankari, MD, PhD, Finnish Lung Health Association, Helsinki, Finland; Merja Kanervisto, PhD, School of Health Sciences, University of Tampere, Finland; Jonna Perälä, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, and Department of Psychiatry, Helsinki University Central Hospital, Finland; Samuli I. Saarni, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Hospital District of Southwest Finland, Turku, Finland; Pekka Jousilahti, MD, PhD, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Jouko Lönnqvist, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki and Helsinki University Central Hospital, Finland; Jaana Suvisaari, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Tampere School of Public Health, University of Tampere, Finland.
authors: Samuli I
authors: SI
authors: Saarni
authors: Krista Partti, MD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki, Finland; Tuula Vasankari, MD, PhD, Finnish Lung Health Association, Helsinki, Finland; Merja Kanervisto, PhD, School of Health Sciences, University of Tampere, Finland; Jonna Perälä, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, and Department of Psychiatry, Helsinki University Central Hospital, Finland; Samuli I. Saarni, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Hospital District of Southwest Finland, Turku, Finland; Pekka Jousilahti, MD, PhD, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Jouko Lönnqvist, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki and Helsinki University Central Hospital, Finland; Jaana Suvisaari, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Tampere School of Public Health, University of Tampere, Finland.
authors: Pekka
authors: P
authors: Jousilahti
authors: Krista Partti, MD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki, Finland; Tuula Vasankari, MD, PhD, Finnish Lung Health Association, Helsinki, Finland; Merja Kanervisto, PhD, School of Health Sciences, University of Tampere, Finland; Jonna Perälä, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, and Department of Psychiatry, Helsinki University Central Hospital, Finland; Samuli I. Saarni, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Hospital District of Southwest Finland, Turku, Finland; Pekka Jousilahti, MD, PhD, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Jouko Lönnqvist, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki and Helsinki University Central Hospital, Finland; Jaana Suvisaari, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Tampere School of Public Health, University of Tampere, Finland.
authors: Jouko
authors: J
authors: Lönnqvist
authors: Krista Partti, MD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki, Finland; Tuula Vasankari, MD, PhD, Finnish Lung Health Association, Helsinki, Finland; Merja Kanervisto, PhD, School of Health Sciences, University of Tampere, Finland; Jonna Perälä, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki, and Department of Psychiatry, Helsinki University Central Hospital, Finland; Samuli I. Saarni, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Hospital District of Southwest Finland, Turku, Finland; Pekka Jousilahti, MD, PhD, Department of Chronic Disease Prevention, Chronic Disease Epidemiology and Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland; Jouko Lönnqvist, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Department of Psychiatry, University of Helsinki and Helsinki University Central Hospital, Finland; Jaana Suvisaari, MD, PhD, Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Helsinki and Tampere School of Public Health, University of Tampere, Finland.
authors: Jaana
authors: J
authors: Suvisaari
mesh_terms: D000328:Adult; D029481:Bronchitis, Chronic / Q000453:epidemiology*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D005387:Finland; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011014:Pneumonia / Q000453:epidemiology*; D012559:Schizophrenia / Q000150:complications*; D057566:Self Report; D012907:Smoking / Q000453:epidemiology*; D013147:Spirometry / Q000706:statistics & numerical data*