title: Pd-catalyzed carbonylative access to aroyl phosphonates from (hetero)aryl bromides.
abstract: The first transition-metal catalysed carbonylation with a phosphorus nucleophile is presented. This transformation provides efficient and mild access to aroylphosphonates under mild conditions, thus ensuring a broad substrate scope. The utility of aroylphosphonates as useful reagents, capable of participating in a number of transformations, is subsequently demonstrated. Furthermore, access to [(13)C]-carbonyl labelled aroylphosphonates is easily realised for the first time, as only a near stoichiometric amount of CO is required applying this carbonylation.
authors: Carbon Dioxide Activation Centre (CADIAC), Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus C, Denmark. ts@chem.au.dk.
authors: Zhong
authors: Z
authors: Lian
authors: Hongfei
authors: H
authors: Yin
authors: Stig D
authors: SD
authors: Friis
authors: Troels
authors: T
authors: Skrydstrup