title: Direct patterning of gold nanoparticles using flexographic printing for biosensing applications.
abstract: In this paper, we have presented the use of flexographic printing techniques in the selective patterning of gold nanoparticles (AuNPs) onto a substrate. Highly uniform coverage of AuNPs was selectively patterned on the substrate surface, which was subsequently used in the development of a glucose sensor. These AuNPs provide a biocompatible site for the attachment of enzymes and offer high sensitivity in the detection of glucose due to their large surface to volume ratio. The average size of the printed AuNPs is less than 60 nm. Glucose sensing tests were performed using printed carbon-AuNP electrodes functionalized with glucose oxidase (GOx). The results showed a high sensitivity of 5.52 μA mM(-1) cm(-2) with a detection limit of 26 μM. We have demonstrated the fabrication of AuNP-based biosensors using flexographic printing, which is ideal for low-cost, high-volume production of the devices.
authors: Multidisciplinary Nanotechnology Centre, College of Engineering, Swansea University, Singleton Park, Swansea, SA2 8PP UK.
authors: Jamie
authors: J
authors: Benson
authors: Multidisciplinary Nanotechnology Centre, College of Engineering, Swansea University, Singleton Park, Swansea, SA2 8PP UK.
authors: Chung Man
authors: CM
authors: Fung
authors: Multidisciplinary Nanotechnology Centre, College of Engineering, Swansea University, Singleton Park, Swansea, SA2 8PP UK.
authors: Jonathan Stephen
authors: JS
authors: Lloyd
authors: Welsh Centre for Printing and Coating, College of Engineering, Swansea University, Singleton Park, Swansea, SA2 8PP UK.
authors: Davide
authors: D
authors: Deganello
authors: College of Science, Department of Physics, Swansea University, Singleton Park, Swansea, SA2 8PP UK.
authors: Nathan Andrew
authors: NA
authors: Smith
authors: Multidisciplinary Nanotechnology Centre, College of Engineering, Swansea University, Singleton Park, Swansea, SA2 8PP UK.
authors: Kar Seng
authors: KS
authors: Teng
keywords: Biosensors 87.85.fk; Nanostructured materials in electrochemistry 82.45.Yz; Surface patterning 81.65.Cf