title: Osteomalacia, severe thoracic deformities and respiratory failure in a young woman with anorexia nervosa.
abstract: The recent trends in avoiding sunbathing and eating fewer fish products have resulted in a high prevalence of vitamin D deficiency in the general Japanese population. We herein report the case of a young woman with enduring anorexia nervosa (AN) who suffered from osteomalacia, thoracic deformities and respiratory failure. Her vitamin D deficiency had been overlooked for years. Although the serum 25-hyroxyvitamin D [25(OH)D] level is a marker of vitamin D stores, it is not routinely examined because the cost is not covered by the national health insurance program. However, measuring the serum 25(OH)D levels in AN patients with hypocalcemia is recommended to prevent osteomalacia and osteoporosis.
authors: Department of Endocrinology and Hypertension, Tokyo Women's Medical University, Japan.
authors: Daisuke
authors: D
authors: Watanabe
authors: Mari
authors: M
authors: Hotta
authors: Atsuhiro
authors: A
authors: Ichihara
mesh_terms: D000328:Adult; D000856:Anorexia Nervosa / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D017610:Calcium Compounds / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D007773:Lactates / Q000627:therapeutic use*; D010018:Osteomalacia / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology; D015995:Prevalence; D012131:Respiratory Insufficiency / Q000209:etiology* / Q000503:physiopathology; D016896:Treatment Outcome; D014807:Vitamin D / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications*
chemical_list: D050071:Bone Density Conservation Agents; D017610:Calcium Compounds; D006887:Hydroxycholecalciferols; D007773:Lactates; D014807:Vitamin D; C110051:calcium lactate; C008088:alfacalcidol