title: Fatal Acute Myeloid Leukemia With 11q23 MLL Gene Rearrangement Following Mitoxantrone Treatment in a Case of Childhood-onset Multiple Sclerosis.
authors: Departments of *Physiology †Neurology ‡Hematology, Oncology and Palliative Medicine, University of Rostock Rostock, Germany.
authors: Robert
authors: R
authors: Patejdl
authors: Saskia
authors: S
authors: Krohn
authors: Hugo
authors: H
authors: Murua Escobar
authors: Uwe K
authors: UK
authors: Zettl
mesh_terms: D000293:Adolescent; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics; D017809:Fatal Outcome; D005260:Female; D015321:Gene Rearrangement; D011495:Histone-Lysine N-Methyltransferase / Q000235:genetics*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000139:chemically induced* / Q000235:genetics; D008942:Mitoxantrone / Q000009:adverse effects*; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000188:drug therapy*; D051788:Myeloid-Lymphoid Leukemia Protein / Q000235:genetics*; D059005:Topoisomerase II Inhibitors / Q000009:adverse effects*
chemical_list: C497422:KMT2A protein, human; D059005:Topoisomerase II Inhibitors; D051788:Myeloid-Lymphoid Leukemia Protein; D008942:Mitoxantrone; D011495:Histone-Lysine N-Methyltransferase