title: Poor housing construction associated with increased malaria incidence in a cohort of young Ugandan children.
abstract: Despite the use of accepted interventions to combat malaria, such as insecticide-treated bed nets and artemisinin-based combination therapy, malaria remains a leading cause of morbidity and mortality in Uganda. We investigated associations between household factors and malaria incidence in a cohort of children living in a highly endemic region of Uganda. Living in a modern house, defined as the use of non-earth floors, non-thatched roofs, and non-mud walls, was associated with approximately half malaria incidence compared with living in a traditional home (incidence rate ratio [IRR] = 0.54, P = 0.001). Other factors found to be associated with a lower incidence of malaria included living in town versus rural setting; sleeping in a room with openings to the outside (windows, eaves, and airbricks); and having an older and more educated primary caregiver. This study adds to the growing body of evidence that improved house construction may be associated with a lower risk of malaria.
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California katherine.snyman@ucsf.edu.
authors: Katherine
authors: K
authors: Snyman
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California.
authors: Florence
authors: F
authors: Mwangwa
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California.
authors: Victor
authors: V
authors: Bigira
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California.
authors: James
authors: J
authors: Kapisi
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California.
authors: Tamara D
authors: TD
authors: Clark
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California.
authors: Beth
authors: B
authors: Osterbauer
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California.
authors: Bryan
authors: B
authors: Greenhouse
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California.
authors: Hugh
authors: H
authors: Sturrock
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California.
authors: Roly
authors: R
authors: Gosling
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California.
authors: Jenny
authors: J
authors: Liu
authors: Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California; Infectious Diseases Research Collaboration, Kampala, Uganda; Department of Epidemiology and Biostatistics, University of California, San Francisco, California.
authors: Grant
authors: G
authors: Dorsey
mesh_terms: D002675:Child, Preschool; D003252:Construction Materials; D005191:Family Characteristics; D005260:Female; D006798:Housing / Q000592:standards / Q000706:statistics & numerical data*; D006801:Humans; D015994:Incidence; D007223:Infant; D008288:Malaria / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014454:Uganda / Q000453:epidemiology