title: Dynamic article: composite antropyloric valve and gracilis muscle transposition for total anorectal reconstruction: a preliminary report.
abstract: BACKGROUND
  Technique and functional outcomes of anorectal reconstruction using an antropyloric graft have been reported previously. This technique had reasonable initial outcomes but lacked voluntary function.
  
  
  OBJECTIVE
  We hereby report the initial results of patients who underwent gracilis muscle wrapping around the perineally transposed antropyloric valve in an attempt to improve voluntary fecal control.
  
  
  METHODS
  This study was conducted at a single tertiary care institution.
  
  
  METHODS
  Eight adult patients (7 men and 1 woman) with a median age of 38 years (range, 19-51 years) underwent this procedure. Seven patients already had anorectal reconstruction with a transposed antropyloric valve, and 1 patient with severely damaged anal sphincter complex underwent single-stage composite antropylorus transposition with a gracilis muscle wrap.
  
  
  METHODS
  The primary outcome measures were anatomical integrity and functional status of the composite graft in the perineum.
  
  
  RESULTS
  No operative mortality or serious procedure-related morbidity occurred in any patient. The median postoperative resting pressure was 29 mmHg (range, 22-38 mmHg) and squeeze pressure was 72.5 mmHg (range, 45-267 mmHg). There was a significant improvement in the squeeze pressure following surgery (p = 0.039). Also, the St. Mark's incontinence scores significantly improved in all patients and varied between 7 and 9 (p = 0.003). The ability to defer defecation and the reduced frequency of leakage accidents were the prime reasons for improved postgraciloplasty outcomes in these patients. On personal interviews, all patients who underwent this procedure were satisfied with the results of their surgery.
  
  
  CONCLUSIONS
  A longer follow-up with a larger sample size is required. Quality-of-life data have not been evaluated in this study.
  
  
  CONCLUSIONS
  Gracilis muscle wrapping around a perineally transposed antropyloric valve is possible and improves the voluntary control and overall functional outcomes in a select group of patients with end-stage fecal incontinence requiring anal replacement (Supplemental Digital Content 1, http://links.lww.com/DCR/A173).
authors: 1 Department of Surgical Gastroenterology, King George's Medical University, Lucknow, India 2 Department of Plastic Surgery, King George's Medical University, Lucknow, India 3 Department of Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India 4 Department of Radiotherapy, King George's Medical University, Lucknow, India.
authors: Abhijit
authors: A
authors: Chandra
authors: Brijesh
authors: B
authors: Mishra
authors: Saket
authors: S
authors: Kumar
authors: Vishal
authors: V
authors: Gupta
authors: M
authors: M
authors: Noushif
authors: U C
authors: UC
authors: Ghoshal
authors: Asha
authors: A
authors: Misra
authors: P K
authors: PK
authors: Srivastava
mesh_terms: D000328:Adult; D001003:Anal Canal / Q000002:abnormalities* / Q000293:injuries / Q000601:surgery*; D000071056:Anorectal Malformations; D001006:Anus, Imperforate / Q000601:surgery*; D002277:Carcinoma / Q000601:surgery*; D004599:Electric Stimulation Therapy; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000637:transplantation*; D010502:Perineum / Q000293:injuries / Q000601:surgery*; D011708:Pylorus / Q000637:transplantation*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012004:Rectal Neoplasms / Q000601:surgery*; D012007:Rectum / Q000002:abnormalities* / Q000601:surgery*; D013848:Thigh; D016896:Treatment Outcome; D055815:Young Adult