title: Daptomycin for a complicated urinary tract infection with vancomycin-resistant Enterococcus faecium in a renal transplant recipient.
abstract: There is an increasing prevalence of urinary tract infection (UTI) caused by multiresistant gram-negative enteric bacilli such as extended-spectrum beta-lactamase as well as Gram-positive enterococci whose vancomycin-resistance can be as high as 25%. We report on a 68-year-old Caucasian female with a UTI caused by a vancomycin-resistant Enterococcus faecium, only tested to be susceptible to gentamycin, linezolid and daptomycin. Within a day after administration of the bactericidal daptomycin clinical and laboratory signs of infection regressed and graft function recovered. Our case suggests that daptomycin might be an effective alternative for UTI caused by vancomycin-resistant enterococci.
authors: Department of Nephrology and Hypertension , Medical School Hannover , Hannover , Germany.
authors: Gabriele
authors: G
authors: Eden
authors: Department of Pulmonary Medicine , Medical School Hannover , Hannover , Germany.
authors: Olaf
authors: O
authors: Burkhardt
authors: Department of Nephrology and Hypertension , Medical School Hannover , Hannover , Germany.
authors: Christian
authors: C
authors: Clajus
authors: Department of Nephrology and Hypertension , Medical School Hannover , Hannover , Germany.
authors: Jan T
authors: JT
authors: Kielstein
keywords: renal transplant recipient; urinary tract infection; vancomycin-resistant entorococci