title: Biodegradable and Titanium Osteosynthesis Provide Similar Stability for Orthognathic Surgery.
abstract: OBJECTIVE
  The purpose of this study was to test the hypothesis that there is no difference in skeletal stability and material-related complications for titanium or biodegradable fixation when used for various orthognathic surgeries.
  
  
  METHODS
  A systematic and electronic search of several databases with specific keywords, a reference search, and a manual search through September 2014 was performed. The inclusion criteria were clinical human studies, including randomized controlled trials, controlled clinical trials, and retrospective studies, with the aim of comparing titanium and biodegradable osteosynthesis after various orthognathic surgeries. The outcome variables of horizontal and vertical relapse using cephalometrics and material usability were statistically analyzed.
  
  
  RESULTS
  The initial PubMed search identified 557 studies, 22 of which met the inclusion criteria (8 randomized controlled trials, 10 controlled clinical trials, and 4 retrospective studies). No statistical difference was found between the 2 groups regarding skeletal stability after various orthognathic surgeries. There was no statistical difference with regard to wound problems, plate and screw removal, and palpability between biodegradable and titanium osteosynthesis, but there was a statistical difference with regard to intraoperative fracture of plates and screws in the biodegradable group.
  
  
  CONCLUSIONS
  The results of this meta-analysis support the hypothesis that biodegradable fixation devices offer similar skeletal stability as titanium fixation for orthognathic surgery. The results of this study also show that titanium fixation produced fewer broken screws during surgery compared with biodegradable screws.
authors: Assistant Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Thamar University, Thamar, Yemen. Electronic address: dressamalmoraissi@gmail.com.
authors: Essam Ahmed
authors: EA
authors: Al-Moraissi
authors: Professor and Chair, Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center, San Antonio, TX.
authors: Edward
authors: E
authors: Ellis
mesh_terms: D001672:Biocompatible Materials; D001860:Bone Plates; D001863:Bone Screws; D005593:Fracture Fixation, Internal / Q000295:instrumentation*; D006801:Humans; D056948:Orthognathic Surgical Procedures; D016032:Randomized Controlled Trials as Topic; D014025:Titanium
chemical_list: D001672:Biocompatible Materials; D014025:Titanium