title: Super High Dosing with a Novel Buttiauxella Phytase Continuously Improves Growth Performance, Nutrient Digestibility, and Mineral Status of Weaned Pigs.
abstract: This study was conducted to evaluate the efficacy of a novel Buttiauxella phytase to pigs fed P-deficient, corn-soybean meal diets. One hundred and twenty crossbred piglets (9.53 ± 0.84 kg) were allocated to one of five treatments which consisted of four low P diets (0.61 % Ca and 0.46 % total P) supplemented with 0, 500, 1,000, or 20,000 FTU/kg phytase as well as a positive control diet (0.77 % Ca and 0.62 % total P). Each treatment had six replicated pens with four pigs per pen. Pigs were fed the experimental diets for 28 days. Phytase supplementation linearly improved (P < 0.05) average daily gain (ADG), feed conversion ratio (FCR), and apparent total tract digestibility (ATTD) of dry matter, gross energy, crude protein, Ca, and P in weaned pigs. Super high dosing with phytase (20,000 FTU/kg) further increased (P < 0.05) ADG compared with 500 FTU/kg phytase inclusion group, as well as ATTD of Ca and P. Metacarpal bone characteristics and several trace mineral concentration in bone, plasma, or organ tissues were linearly (P < 0.05) improved at increasing dose of phytase. Super high dosing with phytase (20,000 FTU/kg) supplementation improved (P < 0.05) Mn and Zn concentration in bone compared to normal dose of phytase supplementation (500 or 1,000 FTU/kg). In conclusion, supplementation of 500 FTU of Buttiauxella phytase/kg and above effectively hydrolyzed phytate in a low-P corn-soybean diet for pigs. In addition, a super high dosing with phytase (20,000 FTU/kg) improved macro- or micro mineral availability and growth performance.
authors: State Key Laboratory of Animal Nutrition, Ministry of Agriculture Feed Industry Centre, China Agricultural University, No. 2. West Yuanmingyuan Road, Beijing, 100193, China.
authors: Zhikai
authors: Z
authors: Zeng
authors: State Key Laboratory of Animal Nutrition, Ministry of Agriculture Feed Industry Centre, China Agricultural University, No. 2. West Yuanmingyuan Road, Beijing, 100193, China.
authors: Qingyun
authors: Q
authors: Li
authors: State Key Laboratory of Animal Nutrition, Ministry of Agriculture Feed Industry Centre, China Agricultural University, No. 2. West Yuanmingyuan Road, Beijing, 100193, China.
authors: Qiyu
authors: Q
authors: Tian
authors: State Key Laboratory of Animal Nutrition, Ministry of Agriculture Feed Industry Centre, China Agricultural University, No. 2. West Yuanmingyuan Road, Beijing, 100193, China.
authors: Panfeng
authors: P
authors: Zhao
authors: State Key Laboratory of Animal Nutrition, Ministry of Agriculture Feed Industry Centre, China Agricultural University, No. 2. West Yuanmingyuan Road, Beijing, 100193, China.
authors: Xiao
authors: X
authors: Xu
authors: Department of Biotechnology, Lund University, Lund, Sweden.|Danisco DuPont, Aarhus, Denmark.
authors: Shukun
authors: S
authors: Yu
authors: State Key Laboratory of Animal Nutrition, Ministry of Agriculture Feed Industry Centre, China Agricultural University, No. 2. West Yuanmingyuan Road, Beijing, 100193, China. piaoxsh@mafic.ac.cn.
authors: Xiangshu
authors: X
authors: Piao
mesh_terms: D010832:6-Phytase / Q000494:pharmacology*; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D015519:Bone Density; D001846:Bone Development / Q000187:drug effects; D019587:Dietary Supplements; D004063:Digestion / Q000187:drug effects*; D004755:Enterobacteriaceae / Q000201:enzymology*; D006128:Growth / Q000187:drug effects*; D008903:Minerals / Q000378:metabolism*; D009752:Nutritional Status / Q000187:drug effects; D010758:Phosphorus / Q000172:deficiency; D013025:Glycine max; D034421:Sus scrofa; D013552:Swine; D003313:Zea mays
chemical_list: D008903:Minerals; D010758:Phosphorus; D010832:6-Phytase
keywords: Bone characteristics; Buttiauxella phytase; Digestibility; Growth performance; Minerals; Pigs