title: Hypothalamic type of hypopituitarism and central diabetes insipidus probably linked to Rathke's cleft cyst.
abstract: A 73-year-old woman was admitted due to weight loss and generalized malaise. The basal levels of all the anterior pituitary hormones, except for prolactin, were reduced. However, they were all elevated in response to exogenous hypothalamic hormones. After starting hydrocortisone replacement, the patient had polyuria of >5,000 mL/day. T1-weighted MRI depicted a low signal of an oval mass in the sella turcica and an iso-intense signal of another mass at the pituitary stalk. These findings indicate a hypothalamic type of hypopituitarism and masked central diabetes insipidus which possibly derived from the atypical occupation of Rathke's cleft cyst at the pituitary stalk.
authors: Department of Medicine, Jichi Medical University Saitama Medical Center, Japan.
authors: Tomoko
authors: T
authors: Asano
authors: Hodaka
authors: H
authors: Yamada
authors: Masashi
authors: M
authors: Yoshida
authors: Atsushi
authors: A
authors: Aoki
authors: Aki
authors: A
authors: Ikoma
authors: Ikuyo
authors: I
authors: Kusaka
authors: Hideo
authors: H
authors: Toyoshima
authors: Masafumi
authors: M
authors: Kakei
authors: San-E
authors: SE
authors: Ishikawa
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D020863:Central Nervous System Cysts / Q000150:complications / Q000473:pathology*; D020790:Diabetes Insipidus, Neurogenic / Q000209:etiology / Q000473:pathology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use*; D007018:Hypopituitarism / Q000209:etiology / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D010911:Pituitary Neoplasms / Q000150:complications / Q000473:pathology*
chemical_list: D000893:Anti-Inflammatory Agents; D006854:Hydrocortisone