title: Seroprevalence of poliovirus antibodies among 7-month-old infants after 4 doses of oral polio vaccine in Sistan-va-Baluchestan, Islamic Republic of Iran.
abstract: Despite high coverage rates of polio vaccine in the Islamic Republic of Iran, the seroconversion rates of infants may be inadequate. This study measured seroprevalence of antibodies against poliovirus serotypes 1 to 3 (PV1, PV2 and PV3) in 7-month-old infants who had received at least 4 doses of trivalent oral polio vaccine. A serosurvey was conducted in 2010 in rural areas of Chabahar, Sistan-va-Baluchestan province. Using cluster sampling, 72 eligible infants were tested for antibody against the 3 poliovirus serotypes according to WHO guidelines. Antibody titres ≥ 1:10 were considered positive. The seropositive rates for antibody against PV1, PV2 and PV3 were 84.7%, 95.8% and 70.8% respectively. Only 63.9% of participants were seropositive for antibodies against all 3 poliovirus serotypes. Except for PV2, the seroprevalence of antibody against the other 2 poliovirus serotypes, especially PV3, was unsatisfactory.
authors: Health Promotion Research Centre, School of Public Health, Zahedan University of Medical Sciences, Zahedan, Islamic Republic of Iran.
authors: S
authors: S
authors: Izadi
authors: School of Public Health, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors: S
authors: S
authors: Shahmahmoodi
authors: Centre for Communicable Disease Control, Ministry of Health and Medical Education, Tehran, Islamic Republic of Iran.
authors: S M
authors: SM
authors: Zahraei
authors: School of Public Health, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors: F
authors: F
authors: Dorostkar
authors: School of Public Health, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
authors: S-R
authors: SR
authors: Majdzadeh
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D004196:Disease Outbreaks / Q000517:prevention & control; D005260:Female; D006801:Humans; D007223:Infant; D007492:Iran; D008297:Male; D017955:Poliovirus / Q000187:drug effects*; D011055:Poliovirus Vaccine, Oral / Q000008:administration & dosage*; D016036:Seroepidemiologic Studies; D011795:Surveys and Questionnaires
chemical_list: D000914:Antibodies, Viral; D011055:Poliovirus Vaccine, Oral