title: Moderately High Dose Zinc Gluconate or Zinc Glycinate: Effects on Plasma Zinc and Erythrocyte Superoxide Dismutase Activities in Young Adult Women.
abstract: Some zinc (Zn) research studies have used either Zn gluconate or Zn glycinate, but the two forms have not been compared much. Therefore, a moderately high dose of the two forms (60 mg Zn/day) were compared in a 6-week intervention in young adult women. Plasma Zn, the traditional assessment of Zn status, was increased in all subjects given Zn glycinate (N = 10), while no significant change was seen overall for Zn gluconate or placebo (N = 10 each). Erythrocyte superoxide dismutase activity, a marker for Zn-induced copper deficiency, was unchanged in all three groups. Thus, for the conditions of this study, Zn glycinate effectively changed Zn status better than Zn gluconate, but neither impacted copper status.
authors: Human Nutrition, Ohio State University, 345 Campbell Hall, 1787 Neil Ave, Columbus, OH, 43210, USA. disilvestro.1@osu.edu.
authors: Robert A
authors: RA
authors: DiSilvestro
authors: Human Nutrition, Ohio State University, 345 Campbell Hall, 1787 Neil Ave, Columbus, OH, 43210, USA.
authors: Erin
authors: E
authors: Koch
authors: Human Nutrition, Ohio State University, 345 Campbell Hall, 1787 Neil Ave, Columbus, OH, 43210, USA.
authors: Linda
authors: L
authors: Rakes
mesh_terms: D000293:Adolescent; D003300:Copper / Q000172:deficiency; D019587:Dietary Supplements; D004912:Erythrocytes / Q000187:drug effects* / Q000201:enzymology*; D005260:Female; D005942:Gluconates / Q000494:pharmacology*; D005998:Glycine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006801:Humans; D010865:Pilot Projects; D013482:Superoxide Dismutase / Q000097:blood*; D055815:Young Adult; D015032:Zinc / Q000097:blood*
chemical_list: D005942:Gluconates; C016838:zinc glycinate; D003300:Copper; D013482:Superoxide Dismutase; D015032:Zinc; C030691:gluconic acid; D005998:Glycine
keywords: Chelates; Gluconate; Glycinate; Superoxide dismutase; Supplementation; Zinc