title: PET/CT imaging for target volume delineation in curative intent radiotherapy of non-small cell lung cancer: IAEA consensus report 2014.
abstract: This document describes best practice and evidence based recommendations for the use of FDG-PET/CT for the purposes of radiotherapy target volume delineation (TVD) for curative intent treatment of non-small cell lung cancer (NSCLC). These recommendations have been written by an expert advisory group, convened by the International Atomic Energy Agency (IAEA) to facilitate a Coordinated Research Project (CRP) aiming to improve the applications of PET based radiation treatment planning (RTP) in low and middle income countries. These guidelines can be applied in routine clinical practice of radiotherapy TVD, for NSCLC patients treated with concurrent chemoradiation or radiotherapy alone, where FDG is used, and where a calibrated PET camera system equipped for RTP patient positioning is available. Recommendations are provided for PET and CT image visualization and interpretation, and for tumor delineation using planning CT with and without breathing motion compensation.
authors: Department of Nuclear Medicine, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address: t.konert@nki.nl.
authors: Tom
authors: T
authors: Konert
authors: Department of Nuclear Medicine, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
authors: Wouter
authors: W
authors: Vogel
authors: Department of Radiation Oncology, Peter MacCallum Cancer Centre, East Melbourne, Australia.
authors: Michael P
authors: MP
authors: MacManus
authors: Department of Radiation Oncology, University Medical Center Freiburg, Freiburg i. Br., Germany.
authors: Ursula
authors: U
authors: Nestle
authors: Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
authors: José
authors: J
authors: Belderbos
authors: Department of Radiation Oncology, St-Luc University Hospital, Brussels, Belgium.
authors: Vincent
authors: V
authors: Grégoire
authors: Section for Biomedical Physics, Department of Radiation Oncology, University Hospital Tübingen, Tübingen, Germany.
authors: Daniela
authors: D
authors: Thorwarth
authors: Department of Nuclear Sciences and Application, Division of Human Health, International Atomic Energy Agency, Vienna, Austria.
authors: Elena
authors: E
authors: Fidarova
authors: Department of Nuclear Sciences and Application, Division of Human Health, International Atomic Energy Agency, Vienna, Austria.
authors: Diana
authors: D
authors: Paez
authors: Nuclear Medicine Department, Humanitas Research Hospital, Rozzano, Italy.
authors: Arturo
authors: A
authors: Chiti
authors: Centre for Cancer Research and Cell Biology, Queen's University of Belfast, Belfast, United kingdom.
authors: Gerard G
authors: GG
authors: Hanna
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000532:radiotherapy*; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy*; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods
keywords: International; Non-small cell lung cancer; PET/CT; Radiation treatment planning; Radiotherapy; Tumor volume delineation