title: Optical coherence tomography assisted retinal nerve fibre layer thickness profile in high myopia.
abstract: BACKGROUND
  To evaluate the association of high myopia with retinal nerve fibre layer (RNFL) thickness by Fourier domain optical coherence tomography (FD OCT).
  
  
  METHODS
  Fifty highly myopic eyes (25 patients) and forty emmetropic eyes (20 Normal subject) were randomly selected after excluding concomitant ophthalmic disorder and RNFL thickness measured using the Fourier domain optical coherence tomography (FD OCT).
  
  
  RESULTS
  The overall mean RNFL thickness in the myopic groups and control were 87.89 μm and 111.64 μm respectively. The mean retinal nerve fibre thickness was significantly less in myopic eyes as compared to control group (p =0.0001). Retinal nerve fibre layer thickness shows topographic double hump pattern in both the groups (myopes and emmetropes).
  
  
  CONCLUSIONS
  Retinal nerve fibre thickness was significantly less in myopic eyes as compared to emmetropic eyes. The retinal nerve fibre layer thinning in high myopes may be confused with open angle glaucoma, a disease also prevalent in high myopes. There is therefore a need to have retinal nerve fibre layer thickness normogram for high myopes of a given population group to avoid wrong interpretation.
authors: Junior Resident, Department of Ophthalmology, JN Medical College , Aligarh, U.P., India .
authors: Mousumi
authors: M
authors: Malakar
authors: Professor, Department of Ophthalmology, JN Medical College , Aligarh, U.P., India .
authors: Syed Nasir
authors: SN
authors: Askari
authors: Professor, Department of Ophthalmology, JN Medical College , Aligarh, U.P., India .
authors: Humayun
authors: H
authors: Ashraf
authors: Assistant Professor, Department of Ophthalmology, JN Medical College , Aligarh, U.P., India .
authors: Abdul
authors: A
authors: Waris
authors: Medical Director, Gandhi Eye Hospital , Aligarh, U.P., India .
authors: Anupam
authors: A
authors: Ahuja
authors: Assistant Professor, Department of Anatomy, HIMSR, Jamia Hamdard , New Delhi, India .
authors: Adil
authors: A
authors: Asghar
keywords: Emmetropic; Glaucoma; Visual disability