title: [Analysis of 2 patients with occupational hard mental lung disease].
abstract: OBJECTIVE
  We sought to master the clinical characteristics and prognosis of hard mental lung disease, improving this disease's diagnosis and treatment quality.
  
  
  METHODS
  We recruited two suspected patients with hard mental lung disease and collected their occupational history, examination results of occupational health, and past medical records. By virtue of laboratory tests, high Kv chest radiography, CT and HRCT of chest, fiberoptic bronchoscopy and ECG examination, diagnostic report was synthesized respectively by respiratory physicians and pathologist from three different agencies. Then the report was submitted to diagnosis organizations of occupational disease, and diagnostic conclusion of occupational disease was drawn after discussion by at least three diagnosticians of occupational disease.
  
  
  RESULTS
  We found that both of the two suspected patients were exposed to dusts of hard metal, and length of exposure service ranged from 8 to 9 years. Clinical manifestations were dominated by dry cough, wheezing after activities, and pathological manifestation was characteristic giant cell interstitial pneumonia. The prognosis and outcome of the disease were different.
  
  
  CONCLUSIONS
  According to exact occupational exposure history, clinical manifestations, combined with the results of high Kv chest radiography, CT of chest and pathological manifestation, it can be diagnosed with hard mental lung disease.
authors: Center for Diseas Control and Prerention of Jiangsu Province, Nanjing 210028 , China.
authors: Bangmei
authors: B
authors: Ding
authors: Lu
authors: L
authors: Ding
authors: Bin
authors: B
authors: Yu
authors: Cunhua
authors: C
authors: Fan
authors: Lei
authors: L
authors: Han
authors: Jinmei
authors: J
authors: Hu
authors: Baoli
authors: B
authors: Zhu
mesh_terms: D000497:Alloys / Q000009:adverse effects*; D001999:Bronchoscopy; D003035:Cobalt / Q000009:adverse effects*; D004391:Dust; D006801:Humans; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000175:diagnosis* / Q000209:etiology*; D009784:Occupational Diseases / Q000175:diagnosis* / Q000209:etiology*; D016273:Occupational Exposure / Q000009:adverse effects; D014414:Tungsten / Q000009:adverse effects*
chemical_list: D000497:Alloys; D004391:Dust; C080121:hard metal; D003035:Cobalt; D014414:Tungsten