title: [Anaphylactic reaction to intravenous glucocorticoid in a patient with chronic obstructive pulmonary disease].
abstract: Serious anaphylactic reactions to systemic glucocorticoids are rare and have previously mainly been reported in patients with asthma or aspirin allergy. We report a case of severe anaphylactic reaction to an intravenous (IV) glucocorticoid in a patient with chronic obstructive pulmonary disease. A 61-year-old male developed severe bronchospasm within seconds after IV injection of methylprednisolone sodium succinate. The condition was immediately treated with adrenaline and the patient recovered quickly. Clinicians should be aware of the possibility of anaphylactic reactions to glucocorticoids.
authors: Fælles Akut Modtagelsen, Sygehus Sønderjylland, Kresten Philipsens Vej 15, 6200 Aabenraa. pernilleudesen@hotmail.com.
authors: Pernille Bækgaard
authors: PB
authors: Udesen
authors: Mats Jacob Hermansson
authors: MJ
authors: Lindberg
mesh_terms: D061605:Administration, Intravenous; D000707:Anaphylaxis / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy; D001986:Bronchial Spasm / Q000139:chemically induced / Q000150:complications / Q000188:drug therapy; D004837:Epinephrine / Q000627:therapeutic use; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008776:Methylprednisolone Hemisuccinate / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications
chemical_list: D005938:Glucocorticoids; D008776:Methylprednisolone Hemisuccinate; D004837:Epinephrine