title: A Randomized Double Blind Clinical Trial on a Sabgh Formulation for Patients With Vitiligo.
abstract: BACKGROUND
  The cosmetic problem that vitiligo produces affects patients psychologically. Many patients with vitiligo are suggested to cover their white skin patches with cosmetic products. There are formulations in traditional Iranian pharmacy to color these white skin patches. In this study, one of these formulations was compared with a cosmetic formulation.
  
  
  METHODS
  Two groups of patients were selected. One group used a marketed formulation and other group used a traditional Iranian Pharmacy formulation. The quality of life of the patients was compared based on the Dermatology Life Quality Index Questionnaire.
  
  
  RESULTS
  Both interventions were associated with statistically improved Dermatology Life Quality Index scores over the 8-week intervention (P < .05), although the difference between the 2 was not statistically significant (P = .436).
  
  
  CONCLUSIONS
  Traditional Iranian Pharmacy formulation is effective in increasing the quality of life in vitiligo patients.
authors: Research centre for traditional medicine and history of medicine, Shiraz University of medical sciences, Shiraz, Iran Department of traditional pharmacy, School of pharmacy, Shiraz University of medical sciences, Shiraz, Iran.
authors: Ayda
authors: A
authors: Hosseinkhani
authors: Department of Quality Control, School of pharmacy, Shiraz University of medical sciences, Shiraz, Iran Department of Pharmaceutics, School of pharmacy, Shiraz University of medical sciences, Shiraz, Iran.
authors: Hashem
authors: H
authors: Montaseri
authors: Department of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Manouchehr
authors: M
authors: Sodaifi
authors: Department of traditional pharmacy, School of pharmacy, Shiraz University of medical sciences, Shiraz, Iran Department of Pharmacognosy, School of pharmacy, Shiraz University of medical sciences, Shiraz, Iran mohaghegh@sums.ac.ir.
authors: Abdolali
authors: A
authors: Mohagheghzadeh
authors: Department of Pharmacognosy, School of pharmacy, Shiraz University of medical sciences, Shiraz, Iran.
authors: Hassan
authors: H
authors: Seradj
authors: Institute of mechanics, Iranian space research center, Shiraz, Iran.
authors: Hassan
authors: H
authors: Afshari-Jouybari
mesh_terms: D000293:Adolescent; D000328:Adult; D002626:Chemistry, Pharmaceutical; D003358:Cosmetics / Q000008:administration & dosage* / Q000737:chemistry; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000008:administration & dosage* / Q000737:chemistry; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014820:Vitiligo / Q000188:drug therapy* / Q000523:psychology; D055815:Young Adult
chemical_list: D003358:Cosmetics; D010936:Plant Extracts
keywords: cosmetics; traditional medicine; vitiligo