title: Ethnobotanical study of Loloh: Traditional herbal drinks from Bali (Indonesia).
abstract: BACKGROUND
  Loloh are herbal drinks produced and consumed exclusively in Bali (Indonesia) to prevent and treat different ailments. This is the first study to document plants species used as Loloh, reporting the phytochemical components and pharmacological properties of the most cited plants. Documenting the plants used in herbal drinks in Bali by local communities to treat various ailments (providing some information on phytochemistry and pharmacology of the most interesting plants).
  
  
  METHODS
  Ethnobotanical data were obtained through semi-structured interviews (individual and group discussions) and questionnaires. Plant specimens were collected, identified and made into herbarium vouchers.
  
  
  RESULTS
  A total of 51 plants species (belonging to 32 families) have been documented for their use in the various preparation of Loloh. Different plants and plant parts are used to prepare Loloh to treat heartburn, fever, diarrhea, hypertension, aphthous stomatitis (canker sores), and other minor health problems. These plants are mainly prepared as decoctions, are juiced or simply added to the preparation. The most cited plants (>30 informants) are Alstonia scholaris (L.) R. Br., Blumea balsamifera (L.) DC., Cinnamomum burmanni Nees ex Bl., and Piper betle L. These plants are well studied with multiple demonstrated pharmacological activities (e.g., antimicrobial, anticancer, antidiabetic).
  
  
  CONCLUSIONS
  The Balinese communities still preserve a rich ethnobotanical knowledge. Several species are well known for their pharmacological properties, but some [such as Pneumatopteris callosa (Blume) Nakai and Dendrocnide stimulans (L. f.) Chew] are understudied and could be promising candidates for further research.
authors: Bali Botanical Gardens, Indonesian Institute of Sciences (LIPI), Candikuning Baturiti, Tabanan 82191, Bali, Indonesia; Department of Science, University Roma Tre, Viale G. Marconi 446, 00146 Rome, Italy. Electronic address: wawan.sujarwo@lipi.go.id.
authors: Wawan
authors: W
authors: Sujarwo
authors: Research Center for Biology, Indonesian Institute of Sciences (LIPI), Cibinong Science Center, Cibinong 16911, West Java, Indonesia. Electronic address: ary.prihardhyanto@lipi.go.id.
authors: Ary Prihardhyanto
authors: AP
authors: Keim
authors: Hakai Institute, Simon Fraser University, 8888 University Drive, Burnaby, BC V5A 1S6, Canada. Electronic address: vsavo@sfu.ca.
authors: Valentina
authors: V
authors: Savo
authors: Istituto Centrale per la Demoetnoantropologia, MiBACT, Piazza Marconi 8-10, I-00144 Rome, Italy. Electronic address: paolomaria.guarrera@beniculturali.it.
authors: Paolo Maria
authors: PM
authors: Guarrera
authors: Department of Science, University Roma Tre, Viale G. Marconi 446, 00146 Rome, Italy. Electronic address: giulia.caneva@uniroma3.it.
authors: Giulia
authors: G
authors: Caneva
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001628:Beverages; D019448:Ethnobotany / Q000379:methods* / Q000639:trends; D020834:Ethnopharmacology / Q000379:methods* / Q000639:trends; D005260:Female; D007722:Health Knowledge, Attitudes, Practice / Q000208:ethnology*; D006801:Humans; D007214:Indonesia / Q000208:ethnology; D008297:Male; D008519:Medicine, Traditional / Q000379:methods / Q000639:trends; D008875:Middle Aged; D028321:Plant Preparations / Q000008:administration & dosage / Q000737:chemistry / Q000302:isolation & purification*; D055815:Young Adult
chemical_list: D028321:Plant Preparations
keywords: Anticancer activity; Bali [6,7 seco angustilobine B, Allylpyrocatechol, Blumeatin, Chavibetol, Cryptomeridiol, Daucosterol, Ecdysterone, Eugenol, Luteolin]; Folk phytotherapy; Herbal drinks; Loloh