title: [Value of mean platelet volume and Gensini score on predicting short-term outcome in acute ST segment elevation myocardial infarction patient post emergency percutaneous coronary intervention].
abstract: OBJECTIVE
  To explore the value of mean platelet volume (MPV) and Gensini score on predicting short-term prognosis of patients with acute ST segment elevation myocardial infarction (STEMI) post emergency percutaneous coronary intervention (PCI).
  
  
  METHODS
  From September 2011 to June 2013, 102 consecutive hospitalized STEMI patients undergoing emergency PCI were included. All patients routine blood test was made immediately after admission, and Gensini score was calculated according to the results of coronary angiography. Incidence of major adverse cardiac events (MACE) during hospitalization and 6 months after PCI was observed.
  
  
  RESULTS
  MPV, Gensini score and percent of coronary artery three vessel lesions were significantly higher in MACE patients than in patients without MACE(P < 0.05 or 0.01). Area under the curve (AUC) of MPV plus Gensini score for predicting in hospital MACE and at 6 months post PCI was 0.836 (95%CI:0.706-0.966, P = 0.003) and 0.718 (95%CI:0.571-0.866, P = 0.006) , respectively. Kaplan-Meier survival analysis showed that incidence of without MACE at 6 months post PCI was significantly lower in patients with high MPV (>10.65 fl) than in patients with low MPV ( ≤ 10.65 fl) at admission (log-rank = 4.272, P = 0.039), and in patients with high Gensini score (>89) than in low Gensini score ( ≤ 89) (log-rank = 7.355, P = 0.007) at admission.
  
  
  CONCLUSIONS
  High MPV and Gensini score are associated with lower MACE during hospitalization and at 6 months after PCI in acute STEMI patient. These two parameters could thus be used to predict short-term MACE in STEMI patients post PCI.
authors: Department of Coronary Heart Disease, Cardiac Center, First Affiliated Hospital, Xinjiang Medical University, Urumqi 830054, China.
authors: Wenpei
authors: W
authors: Qin
authors: Email: yangyn5126@163.com.
authors: Yining
authors: Y
authors: Yang
authors: Xiaomei
authors: X
authors: Li
authors: Li
authors: L
authors: Men
authors: Junlin
authors: J
authors: Guo
authors: Fen
authors: F
authors: Liu
authors: Huiping
authors: H
authors: Sun
authors: Rui
authors: R
authors: Xu
authors: Dongze
authors: D
authors: Li
authors: Yitong
authors: Y
authors: Ma
mesh_terms: D056988:Anterior Wall Myocardial Infarction / Q000628:therapy*; D017023:Coronary Angiography; D006760:Hospitalization; D006801:Humans; D063847:Mean Platelet Volume; D062645:Percutaneous Coronary Intervention; D011379:Prognosis; D016896:Treatment Outcome