title: Long-term impact of full-thickness rectal prolapse treatment on fecal incontinence.
abstract: BACKGROUND
  Fecal incontinence is frequently associated with rectal prolapse, but little is known about recovery after treatment of the prolapse.
  
  
  OBJECTIVE
  We therefore aimed to investigate the long-term outcome of fecal incontinence in a cohort of patients suffering from full-thickness rectal prolapse.
  
  
  METHODS
  A database of 145 patients diagnosed with full-thickness rectal prolapse was compiled prospectively over a 7-year period (2003-2010).
  
  
  METHODS
  Patients were referred to a single institution and assessed by standardized questionnaires, anorectal manometry, endosonography, and evacuation proctography. Fecal incontinence was evaluated according to the Cleveland Clinic Score; continence improvement was defined by ≥50% improvement of the Cleveland Clinic Score.
  
  
  RESULTS
  Among the population studied (134 women, 11 men; median follow-up, 38.9 months [range, 21.2-67.2]), 103 patients (71%) underwent operation for their prolapse and 42 (29%) did not. According to the Cleveland Clinic Score, 139 patients (96%) suffered from fecal incontinence before treatment and 64 (46%) reported improvement at the end of the follow-up. Pretreatment history of incontinence symptoms for >2 years (hazard ratio [HR], 1.99; 95% CI, 1.14-3.46; P = .015) and ventral rectopexy (HR, 1.86; 95% CI, 1.026-3.326; P = .04) were associated with continence improvement. Patients who underwent an operative procedure other than ventral rectopexy had similar outcome as compared with nonoperated patients. Conversely, chronic pelvic pain precluded fecal incontinence improvement (HR, 0.32; 95% CI, 0.135-0.668; P = .0017).
  
  
  CONCLUSIONS
  Follow-up, returned questionnaires, and the heterogeneous reasons put forth for declining surgery may introduce some methodologic bias.
  
  
  CONCLUSIONS
  Fecal incontinence in patients suffering from rectal prolapse is improved when ventral rectopexy is performed compared with other operative or medical therapies.
authors: Department of Hepato-Gastroenterology, University Hospital of Rennes, Pontchaillou, France.
authors: Timothée
authors: T
authors: Wallenhorst
authors: Department of Hepato-Gastroenterology, University Hospital of Rennes, Pontchaillou, France; INSERM U991, University of Rennes 1, Rennes, France.
authors: Guillaume
authors: G
authors: Bouguen
authors: Department of Hepato-Gastroenterology, University Hospital of Rennes, Pontchaillou, France.
authors: Charlène
authors: C
authors: Brochard
authors: Department of Hepatobiliary and Digestive Surgery, University Hospital of Rennes, Pontchaillou, France.
authors: Diane
authors: D
authors: Cunin
authors: Department of Hepatobiliary and Digestive Surgery, University Hospital of Rennes, Pontchaillou, France.
authors: Véronique
authors: V
authors: Desfourneaux
authors: Department of Hepato-Gastroenterology, University Hospital of Rennes, Pontchaillou, France.
authors: Alain
authors: A
authors: Ropert
authors: Department of Hepato-Gastroenterology, University Hospital of Rennes, Pontchaillou, France.
authors: Jean-François
authors: JF
authors: Bretagne
authors: Department of Hepato-Gastroenterology, University Hospital of Rennes, Pontchaillou, France; INSERM U991, University of Rennes 1, Rennes, France. Electronic address: laurent.siproudhis@chu-rennes.fr.
authors: Laurent
authors: L
authors: Siproudhis
mesh_terms: D000368:Aged; D019841:Defecography; D019160:Endosonography; D005242:Fecal Incontinence / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D012005:Rectal Prolapse / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome