title: Ethnic variation in rhegmatogenous retinal detachments.
abstract: OBJECTIVE
  We aimed to investigate the clinical variation of rhegmatogenous retinal detachments (RD) in patients of different ethnicities.
  
  
  METHODS
  Patients presenting with a primary RD from two ethnic groups were recruited from our tertiary referral hospital between August 2010 and December 2012. Patients who self-reported their ethnic origin either as European Caucasian (EC) or South Asian (SA) were included. Exclusion criteria included trauma, previous vitreoretinal procedures, age under 18 years, complicated cataract surgery and the presence of syndromes known to be associated with a high prevalence of RD. Detailed phenotypic data were collected. Descriptive and comparative statistical analyses were undertaken.
  
  
  RESULTS
  1269 Patients were recruited. 1173 (92.4%) were EC. Mean age of onset was 58.3 years (EC) and 54.5 years (SA) (P=0.006). 75.3% EC and 58.4% SA were phakic (P<0.001). 12.8% of EC and 19.4% of SA patients had a lattice retinal degeneration in the affected eye (P=0.003). Refractive myopia was greater in SA patients (mean: -6.1DS) than EC (-4.2DS) (P=0.032). Additionally, SA patients had a greater mean axial length (25.65 mm) than EC (25.06 mm) (P=0.014). No differences were demonstrated in laterality, family history, type of retinal break or macular status.
  
  
  CONCLUSIONS
  SA patients present with RD at an earlier age and have a more severe phenotype than ECs. Future management strategies for RD may need to reflect these differences.
authors: Vitreoretinal Department, Moorfields Eye Hospital, London, UK.
authors: A
authors: A
authors: Chandra
authors: Vitreoretinal Department, Moorfields Eye Hospital, London, UK.
authors: P
authors: P
authors: Banerjee
authors: Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
authors: D
authors: D
authors: Davis
authors: Vitreoretinal Department, Moorfields Eye Hospital, London, UK.
authors: D
authors: D
authors: Charteris
mesh_terms: D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D000368:Aged; D044466:Asian People / Q000208:ethnology*; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000208:ethnology; D011446:Prospective Studies; D012163:Retinal Detachment / Q000208:ethnology*; D017678:Sex Distribution; D014792:Visual Acuity; D044465:White People / Q000208:ethnology*