title: Iris metastasis from prostate carcinoma: a case report and review of the literature.
abstract: Despite the high incidence of prostate carcinoma, metastases of the uvea are very rare and the iris localization is even more. Only a few cases worldwide have been described so far. We report here the case of a 66-year-old man diagnosed with a metastatic prostate carcinoma. Nine months later, he developed brain and skin metastases. A couple of weeks later, the metastatic lesion appeared on his left iris. He has received whole brain radiation therapy including the iris lesion in the radiation fields. Through this case report and a literature review, we discuss the incidence, the different clinical presentations and the impact on the survival prognosis of this uncommon metastatic site.
authors: Radiation Oncology, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.
authors: V
authors: V
authors: Martin
authors: Radiation Oncology, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France. Electronic address: xavier.cuenca@psl.aphp.fr.
authors: X
authors: X
authors: Cuenca
authors: Radiation Oncology, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.
authors: S
authors: S
authors: Lopez
authors: Pathology Department, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.
authors: A-F
authors: AF
authors: Albertini
authors: Radiation Oncology, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.
authors: P
authors: P
authors: Lang
authors: Radiation Oncology, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.
authors: J-M
authors: JM
authors: Simon
authors: Radiation Oncology, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.
authors: C-G
authors: CG
authors: Hémery
authors: Radiation Oncology, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.
authors: L
authors: L
authors: Feuvret
authors: Radiation Oncology, groupe hospitalier Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651 Paris cedex 13, France.
authors: J-J
authors: JJ
authors: Mazeron
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000532:radiotherapy / Q000556:secondary*; D000368:Aged; D001932:Brain Neoplasms / Q000532:radiotherapy / Q000556:secondary; D016371:Cranial Irradiation; D017809:Fatal Outcome; D006801:Humans; D015811:Iris Neoplasms / Q000532:radiotherapy / Q000556:secondary*; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology*
keywords: Cancer de prostate; Iris; Metastasis; Métastase; Prostate carcinoma; Radiation therapy; Radiothérapie; Tumeur uvéal; Uveal tumor