title: A small part of myosin IIB takes on a big role in cell polarity.
abstract: A migrating cell must establish front-to-back polarity in order to move. In this issue, Juanes-Garcia et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201407059) report that a short serine-rich motif in nonmuscle myosin IIB is required to establish the cell's rear. This motif represents a new paradigm for what determines directional cell migration.
authors: Vanderbilt University School of Medicine, Nashville, TN 37232.
authors: Aidan M
authors: AM
authors: Fenix
authors: Vanderbilt University School of Medicine, Nashville, TN 37232 dylan.burnette@vanderbilt.edu.
authors: Dylan T
authors: DT
authors: Burnette
mesh_terms: D000818:Animals; D016764:Cell Polarity; D006801:Humans; D018995:Myosin Heavy Chains / Q000502:physiology*; D024501:Nonmuscle Myosin Type IIB / Q000502:physiology*
chemical_list: D024501:Nonmuscle Myosin Type IIB; D018995:Myosin Heavy Chains