title: The association between LEPR Q223R polymorphisms and breast cancer risk.
abstract: Recently, we have read with great interest the article entitled "The association between polymorphisms in the leptin receptor (LEPR) gene and risk of breast cancer: a systematic review and pooled analysis" published online by Wang et al. (Breast Cancer Res Treat 136:231-239, 2012). This article suggests that the A allele of LEPR gene rs1137101 variant was low-penetrant risk factor for developing breast cancer. The result is encouraging. Nevertheless, several key issues are worth noticing.
authors: Department of Toxicology, Henan Center for Disease Control and Prevention, No.105 of South Nongye Road, Zhengzhou, 450016, China, wangyd76@163.com.
authors: Yadong
authors: Y
authors: Wang
authors: Haiyan
authors: H
authors: Yang
authors: Huiyan
authors: H
authors: Gao
authors: Haiyu
authors: H
authors: Wang
mesh_terms: D001943:Breast Neoplasms; D005260:Female; D056726:Genetic Association Studies; D006801:Humans; D054411:Receptors, Leptin / Q000235:genetics*
chemical_list: D054411:Receptors, Leptin