title: Facile synthesis of nucleic acid-polymer amphiphiles and their self-assembly.
abstract: A solid-phase synthesis for nucleic acid-polymer amphiphiles is developed. Using this strategy, several DNA-b-polymer amphiphiles are synthesized, and their self-assembly in aqueous solution is investigated. This general method can in principle be extended to nearly all polymers synthesized by atom transfer radical polymerization to produce a variety of nucleic acid-polymer conjugates.
authors: Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, USA. k.zhang@neu.edu.
authors: Fei
authors: F
authors: Jia
authors: Xueguang
authors: X
authors: Lu
authors: Xuyu
authors: X
authors: Tan
authors: Ke
authors: K
authors: Zhang
mesh_terms: D007700:Kinetics; D015394:Molecular Structure; D009696:Nucleic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D010316:Particle Size; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D013499:Surface Properties; D013501:Surface-Active Agents / Q000138:chemical synthesis* / Q000737:chemistry; D013816:Thermodynamics
chemical_list: D009696:Nucleic Acids; D011108:Polymers; D013501:Surface-Active Agents