title: Direct access to functionalized benzotropones, azepanes, and piperidines by reductive cross-coupling of α-bromo enones with α-bromo enamides.
abstract: The synthesis of functionalized azepenes and piperidines bearing an α-cycloheptenone or benzotropone derivative has been accomplished through direct reductive cross-coupling of α-bromo eneformamides or enecarbamates with highly versatile α-bromo benzotropone derivatives, under cobalt catalysis. The coupling products have been further elaborated to other synthetically useful aza-heterocyclic frameworks.
authors: Department of Chemistry, Susquehanna University, 514 University Avenue, Selinsgrove, PA 17870, USA. beng@susqu.edu.
authors: Timothy K
authors: TK
authors: Beng
authors: Kayla
authors: K
authors: Sincavage
authors: Ann Wens V
authors: AW
authors: Silaire
authors: Amir
authors: A
authors: Alwali
authors: Daniel P
authors: DP
authors: Bassler
authors: Laura E
authors: LE
authors: Spence
authors: Oliver
authors: O
authors: Beale
mesh_terms: D000577:Amides / Q000737:chemistry*; D001381:Azepines / Q000737:chemistry*; D001965:Bromides / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry; D010880:Piperidines / Q000737:chemistry*; D014334:Tropolone / Q000737:chemistry*
chemical_list: D000577:Amides; D001381:Azepines; D001965:Bromides; D006571:Heterocyclic Compounds; D010880:Piperidines; D014334:Tropolone