title: The effect of upper gastrointestinal system endoscopy process on serum oxidative stress levels.
abstract: Some authors have investigated the effects of oxidative stress in some process such as undergoing laparoscopic. However, the effect of upper gastrointestinal system endoscopy process on oxidative stress is unclear. We evaluated the short-term effect of upper gastrointestinal system endoscopy process on oxidative stress. Thirty patients who underwent endoscopy process and 20 healthy controls were enrolled in the prospective study. Serum total antioxidant capacity and total oxidant status measurements were measured before and after endoscopy process. The ratio percentage of total oxidant status to total antioxidant capacity was regarded as oxidative stress index. Before endoscopy process, serum total antioxidant capacity levels were higher, while serum total oxidant status levels and oxidative stress index values were lower in patients than controls, but this difference was not statistically significant (all, p > 0.05). After endoscopy process, serum total antioxidant capacity and total oxidant status levels were significantly higher in patients than before endoscopy process (both, p < 0.05). However, oxidative stress index values were slight higher in patients but this difference was not statistically significant (p > 0.05). We observed that serum TAC and TOS levels were increased in patients who underwent endoscopy process after endoscopy process. However, short-time upper gastrointestinal system endoscopy process did not cause an important change in the oxidative stress index. Further studies enrolling a larger number of patients are required to clarify the results obtained here.
authors: Department of Internal Medicine, Harran University, School of Medicine, 63000, Sanliurfa, Turkey. mnturan@mail.com.
authors: Mehmet Nuri
authors: MN
authors: Turan
authors: Department of Internal Medicine, Harran University, School of Medicine, 63000, Sanliurfa, Turkey.
authors: Mehmet
authors: M
authors: Aslan
authors: Department of Gastroenterology, Harran University, School of Medicine, Sanliurfa, Turkey.
authors: Filiz Fusun
authors: FF
authors: Bolukbas
authors: Department of Gastroenterology, Harran University, School of Medicine, Sanliurfa, Turkey.
authors: Cengiz
authors: C
authors: Bolukbas
authors: Department of Clinical Biochemistry, Harran University, School of Medicine, Sanliurfa, Turkey.
authors: Sahbettin
authors: S
authors: Selek
authors: Department of Endocrinology, Harran University, School of Medicine, Sanliurfa, Turkey.
authors: Tevfik
authors: T
authors: Sabuncu
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D008297:Male; D016877:Oxidants / Q000378:metabolism*; D018384:Oxidative Stress / Q000502:physiology*; D017382:Reactive Oxygen Species / Q000097:blood*
chemical_list: D000975:Antioxidants; D016877:Oxidants; D017382:Reactive Oxygen Species
keywords: Oxidative stress; Upper gastrointestinal system endoscopy