title: Synergistic inhibition of Clostridium difficile with nisin-lysozyme combination treatment.
abstract: Clostridium difficile vegetative cells were not inhibited completely after a 120-min treatment with 40 nM nisin or 0.8 mM lysozyme. However, these cells were completely inhibited after only a 30-min incubation with both 20 nM nisin and 0.2 mM lysozyme.
authors: Department of Food and Nutrition, Kookmin University, Seoul, Republic of Korea.
authors: Changhoon
authors: C
authors: Chai
authors: Department of Food and Nutrition, Kookmin University, Seoul, Republic of Korea.
authors: Kyung-Soo
authors: KS
authors: Lee
authors: Department of Food and Nutrition, Kookmin University, Seoul, Republic of Korea. Electronic address: swoh@kookmin.ac.kr.
authors: Se-Wook
authors: SW
authors: Oh
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016360:Clostridioides difficile / Q000187:drug effects* / Q000502:physiology; D015169:Colony Count, Microbial; D004357:Drug Synergism; D006801:Humans; D050296:Microbial Viability / Q000187:drug effects; D009113:Muramidase / Q000494:pharmacology*; D009561:Nisin / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D009561:Nisin; D009113:Muramidase
keywords: C. difficile-associated disease; Clostridium difficile; Lysozyme; Nisin; Synergistic inhibition