title: Gastric cancer patients with end-stage renal disease who underwent radical gastrectomy.
abstract: BACKGROUND
  Radical gastrectomy (RG) with lymph node (LN) dissection is a standard procedure for gastric cancer (GC). Patients with end-stage renal disease (ESRD) usually have high risk for any operative procedure. However, information for ESRD on RG for GC is limited.
  
  
  METHODS
  A total of 2,021 GC patients who underwent RG with LN dissection were retrospectively reviewed. Among them, 26 patients had ESRD. The clinicopathological features and surgical outcomes were compared between GC with ESRD (ESRD-GC group) and GC without ESRD (GC group).
  
  
  RESULTS
  ESRD-GC patients could be independently differentiated from GC patients by lower hemoglobin, negative lymph node (LN) involvement and higher postoperative complications. The overall survival rate of ESRD-GC group seemed better than that of GC group patients. Lesser depth of tumor invasion, LN metastasis and lymphatic invasion and early-staged tumor contributed to favorable prognosis of ESRD-GC group of patients.
  
  
  CONCLUSIONS
  RG might be beneficial for GC-ESRD patients especially for early-stage disease; however, RG for GC patients with ESRD should be more cautiously performed, otherwise the benefit might be compromised by higher postoperative complications and even mortality.
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C.
authors: Yu-Yin
authors: YY
authors: Liu
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C.
authors: Chun-Yi
authors: CY
authors: Tsai
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C. yehchunan@gmail.com.
authors: Chun-Nan
authors: CN
authors: Yeh
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C.
authors: Kun-Chun
authors: KC
authors: Chiang
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C.
authors: Shang-Yu
authors: SY
authors: Wang
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C.
authors: Chi-Tung
authors: CT
authors: Cheng
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C.
authors: Chien-Hung
authors: CH
authors: Liao
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C.
authors: Ju-Te
authors: JT
authors: Hsu
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C.
authors: Ta-Sen
authors: TS
authors: Yeh
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C.
authors: Yi-Yin
authors: YY
authors: Jan
authors: Gastric Cancer Team, Department of General Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei, Taiwan, R.O.C.
authors: Miin-Fu
authors: MF
authors: Chen
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005743:Gastrectomy; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000473:pathology / Q000601:surgery*; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*
keywords: ESRD; gastrectomy; gastric cancer