title: [Detection of chromosomal aneuploidies in spontaneous abortion samples by fluorescence in situ hybridization].
abstract: OBJECTIVE
  To analyze 81 spontaneous abortion samples with fluorescence in situ hybridization (FISH).
  
  
  METHODS
  Chromosome 13, 21, 16, 22, 18, X and Y probes were used to detect the samples.
  
  
  RESULTS
  FISH was successful in 80 cases (98.77%). Among these, 35 (43.75%) had an abnormal karyotype, which included 19 autosomal aneuploidies, 6 sex chromosome aneuploidies, 9 triploidies and 1 tetraploidy.
  
  
  CONCLUSIONS
  FISH is a rapid and easy method for detecting chromosomal aneuploidies in spontaneous abortion samples, and has a higher detection rate in early spontaneous abortion samples.
authors: Sichuan Provincial Maternal and Child Health Hospital, Chengdu, Sichuan 610041, P.R. China. lyunxing2002@sina.cn.
authors: Ping
authors: P
authors: Wei
authors: Yunxing
authors: Y
authors: Li
authors: Chun
authors: C
authors: Chen
authors: Lan
authors: L
authors: Zeng
authors: Shengfang
authors: S
authors: Qin
authors: Xueyan
authors: X
authors: Wang
authors: Na
authors: N
authors: Xi
mesh_terms: D000022:Abortion, Spontaneous / Q000175:diagnosis / Q000235:genetics*; D000328:Adult; D000782:Aneuploidy; D002869:Chromosome Aberrations; D033481:Chromosomes, Mammalian / Q000235:genetics*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011296:Prenatal Diagnosis; D055815:Young Adult