title: Quantitative assessment of cervical vertebral maturation using cone beam computed tomography in Korean girls.
abstract: This study was aimed to examine the correlation between skeletal maturation status and parameters from the odontoid process/body of the second vertebra and the bodies of third and fourth cervical vertebrae and simultaneously build multiple regression models to be able to estimate skeletal maturation status in Korean girls. Hand-wrist radiographs and cone beam computed tomography (CBCT) images were obtained from 74 Korean girls (6-18 years of age). CBCT-generated cervical vertebral maturation (CVM) was used to demarcate the odontoid process and the body of the second cervical vertebra, based on the dentocentral synchondrosis. Correlation coefficient analysis and multiple linear regression analysis were used for each parameter of the cervical vertebrae (P < 0.05). Forty-seven of 64 parameters from CBCT-generated CVM (independent variables) exhibited statistically significant correlations (P < 0.05). The multiple regression model with the greatest R (2) had six parameters (PH2/W2, UW2/W2, (OH+AH2)/LW2, UW3/LW3, D3, and H4/W4) as independent variables with a variance inflation factor (VIF) of <2. CBCT-generated CVM was able to include parameters from the second cervical vertebral body and odontoid process, respectively, for the multiple regression models. This suggests that quantitative analysis might be used to estimate skeletal maturation status.
authors: Department of Orthodontics, Dental Research Institute, Pusan National University Dental Hospital, Geumoro 20, Yangsan 626787, Republic of Korea ; Department of Orthodontics, School of Dentistry, Pusan National University, Yangsan 626870, Republic of Korea.
authors: Bo-Ram
authors: BR
authors: Byun
authors: Department of Orthodontics, Dental Research Institute, Pusan National University Dental Hospital, Geumoro 20, Yangsan 626787, Republic of Korea ; Department of Orthodontics, School of Dentistry, Pusan National University, Yangsan 626870, Republic of Korea ; Department of Orthodontics, Biomedical Research Institute, Pusan National University Hospital, Gudeokro 179, Busan 602739, Republic of Korea.
authors: Yong-Il
authors: YI
authors: Kim
authors: Department of Orthodontics, School of Dentistry, Showa University, Tokyo 1428555, Japan.
authors: Tetsutaro
authors: 0000-0001-9806-7163
authors: T
authors: Yamaguchi
authors: Department of Orthodontics, School of Dentistry, Showa University, Tokyo 1428555, Japan.
authors: Koutaro
authors: K
authors: Maki
authors: Department of Orthodontics, Dental Research Institute, Pusan National University Dental Hospital, Geumoro 20, Yangsan 626787, Republic of Korea ; Department of Orthodontics, School of Dentistry, Pusan National University, Yangsan 626870, Republic of Korea.
authors: Woo-Sung
authors: WS
authors: Son
mesh_terms: D000293:Adolescent; D000465:Algorithms; D001846:Bone Development; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging*; D002648:Child; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D005260:Female; D006801:Humans; D011857:Radiographic Image Interpretation, Computer-Assisted; D012016:Reference Values; D012044:Regression Analysis; D056910:Republic of Korea