title: [Therapeutic effect of 138 imported falciparum malaria patients].
abstract: OBJECTIVE
  To summarize the clinical characteristics of imported falciparum malaria patients and the treatment, so as to provide the evidences for improving the diagnosis and treatment of the disease.
  
  
  METHODS
  A total of 138 imported falciparum malaria patients who received the treatment in Shandong Institute of Parasitic Diseases from January 2007 to February 2013 were adopted as the observation subjects, and their clinical data were collected and analyzed.
  
  
  RESULTS
  All the 138 patients were back from African countries. The main manifestations were fever, headache, asthenia, and hepatosplenomegaly, and most of them were with decreased RBC, PLT levels and increased LDH levels, and 36.96% of them were misdiagnosed as respiratory diseases, nephritis, hepatitis and so on. Through antimalarial treatment of artemether or artesunate or dihydroartemisinin and primaquine, or dihydroartemisinin and piperaquine, and symptomatic treatment, the short-term and long-term cure rates were 98.55% and 94.93% respectively, with 1 case unrecovered and 1 died.
  
  
  CONCLUSIONS
  Artemisinins are still the most effective antimalarial drugs for falciparum malaria. However, some patients recrudesce as the Plasmodium in their body is resistant or insensitive to these drugs. We should pay more attention to the antimalarial and symptomatic treatments in the early stage of severe malaria so as to improve the cure rate.
authors: Zhen-Hua
authors: ZH
authors: Yu
authors: Fu-Yong
authors: FY
authors: Wang
authors: Dong-Dong
authors: DD
authors: Wei
authors: Bin
authors: B
authors: Yin
authors: Yan-Bin
authors: YB
authors: Wei
authors: Gui-Hua
authors: GH
authors: Zhao
authors: Ben-Gang
authors: BG
authors: Zhang
authors: Yong-Bin
authors: YB
authors: Wang
mesh_terms: D000328:Adult; D000349:Africa; D000962:Antimalarials / Q000627:therapeutic use*; D000077549:Artemether; D037621:Artemisinins / Q000627:therapeutic use; D000077332:Artesunate; D002681:China; D003951:Diagnostic Errors; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis / Q000188:drug therapy* / Q000469:parasitology / Q000635:transmission; D008297:Male; D008875:Middle Aged; D010963:Plasmodium falciparum / Q000187:drug effects*; D012189:Retrospective Studies; D014195:Travel; D055815:Young Adult
chemical_list: D000962:Antimalarials; D037621:Artemisinins; D000077332:Artesunate; C039060:artenimol; D000077549:Artemether