title: High-resolution genomic analysis: the tumor-immune interface comes into focus.
abstract: A genomic analysis of heterogeneous colorectal tumor samples has uncovered interactions between immunophenotype and various aspects of tumor biology, with implications for informing the choice of immunotherapies for specific patients and guiding the design of personalized neoantigen-based vaccines.
authors: Jonathan J
authors: JJ
authors: Havel
authors: Timothy A
authors: TA
authors: Chan
mesh_terms: D000951:Antigens, Neoplasm / Q000235:genetics* / Q000276:immunology; D015179:Colorectal Neoplasms / Q000235:genetics / Q000276:immunology* / Q000628:therapy; D006801:Humans; D016130:Immunophenotyping; D007167:Immunotherapy; D016246:Lymphocytes, Tumor-Infiltrating / Q000276:immunology* / Q000473:pathology; D019139:Tumor Escape / Q000235:genetics / Q000276:immunology
chemical_list: D000951:Antigens, Neoplasm