title: Palladium-Catalyzed Ligand-Directed Oxidative Functionalization of Cyclopropanes.
abstract: This report describes the Pd-catalyzed functionalization of cyclopropanes containing oxazoline, oxime ether, and pyridine directing groups. Three different oxidants were examined in these studies: IOAc, PhI(OAc)2, and benzoquinone. The reactions yielded products derived from 2° sp3C-H functionalization and/or C-C activation of the cyclopropane ring. The outcome and the product distributions were highly dependent on the structure of the substrate and the nature of the oxidant.
authors: University of Michigan, Department of Chemistry, 930 N. University Ave, Ann Arbor, MI 48109, USA.
authors: Asako
authors: A
authors: Kubota
authors: University of Michigan, Department of Chemistry, 930 N. University Ave, Ann Arbor, MI 48109, USA.
authors: Melanie S
authors: MS
authors: Sanford
keywords: C-H functionalization; cleavage; cyclopropane; homogeneous catalysis; palladium