title: Imaging of Tumor Angiogenesis for Radiologists--Part 2: Clinical Utility.
abstract: Angiogenesis is a key cancer hallmark involved in tumor growth and metastasis development. Angiogenesis and tumor microenvironment significantly influence the response of tumors to therapies. Imaging techniques have changed our understanding of the process of angiogenesis, the resulting vascular performance, and the tumor microenvironment. This article reviews the status and potential clinical value of the imaging modalities used to assess the status of tumor vasculature in vivo, before, during, and after treatment.
authors: Department of Radiology, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain. Electronic address: roberto.garcia.figueiras@sergas.es.
authors: Roberto
authors: R
authors: García-Figueiras
authors: Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Northwood, Middlesex, England, UK.
authors: Anwar R
authors: AR
authors: Padhani
authors: Klinik für Nuklearmedizin, Universitätsklinikum Ulm; Ulm, Germany.
authors: Ambros J
authors: AJ
authors: Beer
authors: Department of Radiology, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
authors: Sandra
authors: S
authors: Baleato-González
authors: Department of Radiology, Clínica Girona, IDI, University of Girona, Girona, Spain.
authors: Joan C
authors: JC
authors: Vilanova
authors: Advanced Medical Imaging, Clinica Las Nieves, SERCOSA (Servicio Radiologia Computerizada), Grupo Health Time, Jaén, Spain; Department of Radiology, Case Western Reserve University, Cleveland, OH.
authors: Antonio
authors: A
authors: Luna
authors: Department of Radiology, Hospital Clínic Barcelona, Barcelona, Spain.
authors: Laura
authors: L
authors: Oleaga
authors: Department of Radiotherapy, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
authors: Antonio
authors: A
authors: Gómez-Caamaño
authors: Functional Imaging, Royal Marsden Hospital, Sutton, Surrey, England, UK.
authors: Dow-Mu
authors: DM
authors: Koh
mesh_terms: D015415:Biomarkers; D005544:Forecasting; D006801:Humans; D008991:Monitoring, Physiologic / Q000379:methods; D009362:Neoplasm Metastasis / Q000473:pathology; D009367:Neoplasm Staging / Q000379:methods; D009369:Neoplasms / Q000473:pathology*; D009389:Neovascularization, Pathologic / Q000473:pathology* / Q000628:therapy; D010347:Patient Care Planning; D011379:Prognosis
chemical_list: D015415:Biomarkers