title: The mortality of neonatal herpes simplex virus infection.
abstract: This retrospective study characterized the clinical course of 13 neonates who died with herpes simplex virus infection from 2001 to 2011, representing a 26% case-fatality rate. Fatal disease developed at ≤ 48 hours of age in one-third of infants, was mostly disseminated disease, and occurred despite early administration of high-dose acyclovir therapy.
authors: Department of Pediatrics, Universidad del Valle, Cali, Colombia; Centro de Estudios en Infectología Pediátrica, Cali, Colombia. Electronic address: Eduardo.lopez@ceiponline.org.
authors: Eduardo
authors: E
authors: Lopez-Medina
authors: Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX.
authors: Joseph B
authors: JB
authors: Cantey
authors: Department of Pediatrics, Nationwide Children's Hospital, The Ohio State University, Columbus, OH.
authors: Pablo J
authors: PJ
authors: Sánchez
mesh_terms: D005260:Female; D006561:Herpes Simplex / Q000175:diagnosis / Q000401:mortality*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000401:mortality*; D012189:Retrospective Studies