title: [The role of surrogate alcoholic beverages in the development of hemorrhage in the patients presenting with Mallory-Weiss syndrome].
abstract: The objective of the present work was to study the pathological changes in various organs and tanatogenesis associated with Mallory-Weiss syndrome making use of the forensic medical and clinical materials. It was shown that the main cause of unrestrained vomiting resulting from alcoholic intoxication and leading to perfusive bleeding is not only the direct action of ethanol and surrogate alcohol on gastroesophageal mucosa and induced thrombocytopenia. Another cause may be brain oedema with subsequent cerebral herniation and irritation of the pseudobulbar centres responsible for the initiation of the vomiting reflex. The authors propose recommendations for forensic medical diagnostics of the cases of such hemorrhage.
authors: Kafedra nervnyh boleznej lechebnogo fakul'teta Moskovskogo gosudarstvennogo mediko-stomatologicheskogo universiteta im. A.I. Evdokimova, Moskva, Rossija, 125289.
authors: A L
authors: AL
authors: Pavlov
authors: FGBU 'Rossijskij tsentr sudebno-meditsinskoj ekspertizy' Minzdrava Rossii, Moskva, Rossija, 125284.
authors: D V
authors: DV
authors: Bogomolov
authors: Kafedra nervnyh boleznej lechebnogo fakul'teta Moskovskogo gosudarstvennogo mediko-stomatologicheskogo universiteta im. A.I. Evdokimova, Moskva, Rossija, 125289.
authors: A A
authors: AA
authors: Savin
mesh_terms: D000328:Adult; D000368:Aged; D000434:Alcoholic Beverages / Q000009:adverse effects* / Q000145:classification; D000437:Alcoholism / Q000150:complications* / Q000175:diagnosis / Q000401:mortality; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced* / Q000188:drug therapy / Q000209:etiology / Q000401:mortality; D006801:Humans; D008309:Mallory-Weiss Syndrome / Q000150:complications* / Q000175:diagnosis / Q000401:mortality; D008875:Middle Aged; D011205:Povidone / Q000008:administration & dosage / Q000627:therapeutic use; D016896:Treatment Outcome; D014839:Vomiting / Q000150:complications / Q000175:diagnosis / Q000401:mortality
chemical_list: D011205:Povidone