title: Controlled in vivo swimming of a swarm of bacteria-like microrobotic flagella.
abstract: In vivo imaging and actuation of a swarm of magnetic helical microswimmers by external magnetic fields (less than 10 mT) in deep tissue is demonstrated for the first time. This constitutes a major milestone in the field, yielding a generation of micrometer-scale transporters with numerous applications in biomedicine including synthetic biology, assisted fertilization, and drug/gene delivery.
authors: Nanomedicine Lab, Faculty of Medical & Human Sciences and National Graphene Institute, University of Manchester, AV Hill Building, Manchester, M13 9PT, UK.|UCL Faculty of Life Sciences, University College London, Brunswick Square, London, WC1N 1AX, UK.
authors: Ania
authors: A
authors: Servant
authors: Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH-8092, Switzerland.
authors: Famin
authors: F
authors: Qiu
authors: Nanomedicine Lab, Faculty of Medical & Human Sciences and National Graphene Institute, University of Manchester, AV Hill Building, Manchester, M13 9PT, UK.|UCL Faculty of Life Sciences, University College London, Brunswick Square, London, WC1N 1AX, UK.
authors: Mariarosa
authors: M
authors: Mazza
authors: Nanomedicine Lab, Faculty of Medical & Human Sciences and National Graphene Institute, University of Manchester, AV Hill Building, Manchester, M13 9PT, UK.|UCL Faculty of Life Sciences, University College London, Brunswick Square, London, WC1N 1AX, UK.
authors: Kostas
authors: K
authors: Kostarelos
authors: Institute of Robotics and Intelligent Systems, ETH Zurich, Zurich, CH-8092, Switzerland.
authors: Bradley J
authors: BJ
authors: Nelson
mesh_terms: D000818:Animals; D001419:Bacteria; D018407:Bacterial Physiological Phenomena; D005407:Flagella / Q000502:physiology*; D005456:Fluorescent Dyes / Q000737:chemistry; D005947:Glucose; D006531:HEPES; D060526:Magnetic Fields; D051379:Mice; D008807:Mice, Inbred BALB C; D008954:Models, Biological; D009532:Nickel / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry; D010529:Peritoneal Cavity; D058105:Polymerization; D012399:Rotation; D044967:Serum; D013550:Swimming / Q000502:physiology*; D014025:Titanium / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; C009495:titanium dioxide; D009532:Nickel; D014025:Titanium; D005947:Glucose; D006531:HEPES; D010100:Oxygen
keywords: delivery; microrobots; nanomedicine; targeting; wireless navigation