title: High production of fumaric acid from xylose by newly selected strain Rhizopus arrhizus RH 7-13-9#.
abstract: Fumaric acid, as an important material for polymerization, is highly expected to be produced by fermentation of lignocellulosic biomass which is composed of cellulose, hemicellulose and lignin. Xylose as the main component of hemicellulose cannot be efficiently utilized by most of the common fermentation. In this study, a new strain Rhizopus arrhizus RH 7-13-9# was selected from the R. arrhizus RH 7-13 through a novel convenient and efficient selection method. Efficient production of fumaric acid (45.31 g/L) from xylose was achieved by the new strain, and the volumetric productivity was still 0.472 g/L h. Moreover, the conversion of xylose reached 73% which is close to the theoretic yield (77%). The production of fumaric acid was increased approximate by 172%, compared with the initial strain counterpart. These results indicated that xylose, as the main component of hemicellulose, has a promising application for the production of fumaric acid on an industrial-scale.
authors: Beijing Bioprocess Key Laboratory, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, PR China.
authors: Huan
authors: H
authors: Liu
authors: Beijing Bioprocess Key Laboratory, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, PR China.
authors: Weinan
authors: W
authors: Wang
authors: Beijing Bioprocess Key Laboratory, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, PR China; Amoy - BUCT Industrial Bio-technovation Institute, Amoy 361022, PR China. Electronic address: dengli@mail.buct.edu.cn.
authors: Li
authors: L
authors: Deng
authors: Beijing Bioprocess Key Laboratory, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, PR China; State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, PR China.
authors: Fang
authors: F
authors: Wang
authors: Beijing Bioprocess Key Laboratory, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, PR China.
authors: Tianwei
authors: T
authors: Tan
mesh_terms: D018914:Cells, Immobilized / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D005285:Fermentation; D005650:Fumarates / Q000302:isolation & purification*; D012233:Rhizopus / Q000378:metabolism*; D014994:Xylose / Q000378:metabolism*
chemical_list: D005650:Fumarates; C032005:fumaric acid; D014994:Xylose
keywords: Fumaric acid; Rhizopus arrhizus; Xylose