title: AVIA v2.0: annotation, visualization and impact analysis of genomic variants and genes.
abstract: As sequencing becomes cheaper and more widely available, there is a greater need to quickly and effectively analyze large-scale genomic data. While the functionality of AVIA v1.0, whose implementation was based on ANNOVAR, was comparable with other annotation web servers, AVIA v2.0 represents an enhanced web-based server that extends genomic annotations to cell-specific transcripts and protein-level functional annotations. With AVIA's improved interface, users can better visualize their data, perform comprehensive searches and categorize both coding and non-coding variants.
  
  
  METHODS
  AVIA is freely available through the web at http://avia.abcc.ncifcrf.gov.
  
  
  BACKGROUND
  Hue.Vuong@fnlcr.nih.gov
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors: Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
authors: Hue
authors: H
authors: Vuong
authors: Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
authors: Anney
authors: A
authors: Che
authors: Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
authors: Sarangan
authors: S
authors: Ravichandran
authors: Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
authors: Brian T
authors: BT
authors: Luke
authors: Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
authors: Jack R
authors: JR
authors: Collins
authors: Advanced Biomedical Computing Center, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
authors: Uma S
authors: US
authors: Mudunuri
mesh_terms: D030541:Databases, Genetic; D005796:Genes; D014644:Genetic Variation; D020407:Internet; D058977:Molecular Sequence Annotation; D012984:Software