title: Iron- or silver-catalyzed oxidative fluorination of cyclopropanols for the synthesis of β-fluoroketones.
abstract: The Fe(III)- or Ag(I)-catalyzed oxidative fluorination of cyclopropanols via radical rearrangement is disclosed. This process features a straightforward and highly effective protocol for the site-specific synthesis of β-fluoroketones and represents an expedient method for the synthesis of γ-, δ- and ε-fluoroketones. Notably, this reaction proceeds at room temperature and tolerates a diverse array of cyclopropanols.
authors: Department of Chemistry, University of Science and Technology of China, Hefei, Anhui, P. R. China 230026.
authors: Shichao
authors: S
authors: Ren
authors: Chao
authors: C
authors: Feng
authors: Teck-Peng
authors: TP
authors: Loh
mesh_terms: D002384:Catalysis; D004988:Ethers, Cyclic / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry*; D007501:Iron / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis*; D010084:Oxidation-Reduction; D012834:Silver / Q000737:chemistry*
chemical_list: D004988:Ethers, Cyclic; D007659:Ketones; C043657:cyclopropanol; D005461:Fluorine; D012834:Silver; D007501:Iron