title: Clinical and therapeutic correlations in patients with slight acute pancreatitis.
abstract: BACKGROUND
  Acute pancreatitis is an inflammatory disease of the pancreas due to enzymatic autodigestion which can cause necrosis or multiple organ failure; its pathophysiology is not fully known yet.
  
  
  OBJECTIVE
  To evaluate the correlation between clinical and therapeutic data in patients with mild acute pancreatitis.
  
  
  METHODS
  A retrospective study in 55 medical records of patients admitted with acute mild pancreatitis was realized to analyze the association between age, leukocytosis, serum glutamic-oxaloacetic transaminase and lactate dehydrogenase, glucose, antibiotics, time admission and Ranson's scores.
  
  
  RESULTS
  There was a positive association between less intensive care (strict hydration, analgesia and monitoring of vital signs), early antibiotic therapy (monotherapy), early return to diet after 48 hours and laboratory control of the serum amylase and lipase (high in the first week and decreasing after 10 days, without any prognostic value).
  
  
  CONCLUSIONS
  Changes in the management of patients with mild acute pancreatitis, such as enteral nutrition, rational use of lower spectrum antibiotics and intensive care, have contributed significantly to the reduction of hospitalization time and mortality.
authors: Department of Anatomy, São José do Rio Preto Medical School, São José do Rio Preto, São Paulo, Brazil.
authors: Clewis Henri
authors: CH
authors: Munhoz-Filho
authors: Department of Anatomy, São José do Rio Preto Medical School, São José do Rio Preto, São Paulo, Brazil.
authors: Fernando
authors: F
authors: Batigália
authors: Department of Anatomy, São José do Rio Preto Medical School, São José do Rio Preto, São Paulo, Brazil.
authors: Hamilton Luiz Xavier
authors: HL
authors: Funes
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis* / Q000188:drug therapy*; D012189:Retrospective Studies; D012720:Severity of Illness Index
chemical_list: D000900:Anti-Bacterial Agents