title: Prevalence of post-stroke cognitive impairment in china: a community-based, cross-sectional study.
abstract: International hospital-based studies have indicated a high risk of cognitive impairment after stroke, evidence from community-based studies in China is scarce. To determine the prevalence of post-stroke cognitive impairment (PSCI) and its subtypes in stroke survivors residing in selected rural and urban Chinese communities, we conducted a community-based, cross-sectional study in 599 patients accounting for 48% of all stroke survivors registered in the 4 communities, who had suffered confirmed strokes and had undergone cognitive assessments via the Montreal Cognitive Assessment (MoCA), Mini-Mental State Examination (MMSE), and Hachinski Ischemia Scale (HIS). Detection of PSCI was based on scores in these neuropsychological scales. Factors potentially impacting on occurrence of PSCI were explored by comparing demographic characteristics, stroke features, and cardiovascular risk factors between patients with and without PSCI. The overall prevalence of PSCI was 80.97% (95%CI: 77.82%-84.11%), while that of non-dementia PSCI (PSCI-ND) and post-stroke vascular dementia (PSD) was 48.91% (95%CI: 44.91%-52.92%) and 32.05% (95%CI: 28.32%-35.79%), respectively. Prior stroke and complications during the acute phase were independent risk factors for PSCI. The risk of recurrent stroke survivors having PSCI was 2.7 times higher than for first-episode survivors, and it was 3 times higher for those with complications during the acute phase than for those without. The higher prevalence of PSCI in this study compared with previous Chinese studies was possibly due to the combined effects of including rural stroke survivors, a longer period from stroke onset, and different assessment methods. There is an urgent need to recognize and prevent PSCI in stroke patients, especially those with recurrent stroke and complications during the acute phase.
authors: Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China; Department of Epidemiology and Bio-Statistics, Peking University Health Science Center, Beijing, China.
authors: Yanji
authors: Y
authors: Qu
authors: Department of Epidemiology and Bio-Statistics, Peking University Health Science Center, Beijing, China.
authors: Lin
authors: L
authors: Zhuo
authors: Fangshan District Center for Disease Control and Prevention, Beijing, China.
authors: Na
authors: N
authors: Li
authors: Bansongyuan Center of Community Health Services, Huangpu District, Shanghai, China.
authors: Yiqing
authors: Y
authors: Hu
authors: East Nanjing Road Center of Community Health Services, Huangpu District, Shanghai, China.
authors: Weihua
authors: W
authors: Chen
authors: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
authors: Yun
authors: Y
authors: Zhou
authors: Department of Epidemiology and Bio-Statistics, Peking University Health Science Center, Beijing, China.
authors: Jinwei
authors: J
authors: Wang
authors: Department of Epidemiology and Bio-Statistics, Peking University Health Science Center, Beijing, China.
authors: Qingmei
authors: Q
authors: Tao
authors: Department of Epidemiology and Bio-Statistics, Peking University Health Science Center, Beijing, China.
authors: Jing
authors: J
authors: Hu
authors: Department of Epidemiology and Bio-Statistics, Peking University Health Science Center, Beijing, China.
authors: Xiaolu
authors: X
authors: Nie
authors: Department of Epidemiology and Bio-Statistics, Peking University Health Science Center, Beijing, China.
authors: Siyan
authors: S
authors: Zhan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000150:complications / Q000503:physiopathology; D002681:China; D003072:Cognition Disorders / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D020521:Stroke / Q000150:complications / Q000503:physiopathology*