title: [18F-FDG positron emission tomography in the diagnosis and staging of marginal zone non-Hodgkin lymphomas].
abstract: OBJECTIVE
  To investigate the diagnostic value of 18F-FDG positron emission tomography (PET) in the diagnosis and staging of marginal zone non-Hodgkin lymphomas (NHLs).
  
  
  METHODS
  Twenty-four patients with new-onset NHLs were examined. Extranodal MALT lymphoma, splenic marginal zone lymphoma (MZL), and nodal MZL lymphoma were diagnosed in 18, 3, and 3 patients, respectively. 18F-FDG PET was carried out by the standard protocol via whole-body examination, by estimating the standardized tracer uptake value (SUV(max)) in the abnormal foci.
  
  
  RESULTS
  Most (83.3%) of the examinees were found to have abnormal tracer hyperfixation foci. The mean SUV(max) was 5.05 ± 0.9. There was no correlation between SUV(max) in the tumor foci and their metabolic sizes (r = 0.1; p = 0.7). No significant differences between the mean SUV(max) were found in patients with different histological types of MZL (p > 0.05). Disease staging by PET and other diagnostic methods yielded contradictory results in three patients. The final analysis suggested that the stage had been correctly determined in all the 3 patients from PET findings.
  
  
  CONCLUSIONS
  The results of 18F-FDG PET suggest that it is of high iagnostic value in imag-ng marginal zone NHLs. The major advantage of PET is that it can accu-ately stage the disease, which can provide a ra-ionale for optimal treat-ent policy.
authors: M M
authors: MM
authors: Khodzhibekova
authors: L A
authors: LA
authors: Tiutin
authors: N A
authors: NA
authors: Kostenikov
authors: N V
authors: NV
authors: Il'in
authors: Iu N
authors: IuN
authors: Vinogradova
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18