title: Thymus vulgaris essential oil: chemical composition and antimicrobial activity.
abstract: The study was designed to determine the chemical composition and antimicrobial properties of the essential oil of Thymus vulgaris cultivated in Romania. The essential oil was isolated in a yield of 1.25% by steam distillation from the aerial part of the plant and subsequently analyzed by GC-MS. The major components were p-cymene (8.41%), γ-terpinene (30.90%) and thymol (47.59%). Its antimicrobial activity was evaluated on 7 common food-related bacteria and fungus by using the disk diffusion method. The results demonstrate that the Thymus vulgaris essential oil tested possesses strong antimicrobial properties, and may in the future represent a new source of natural antiseptics with applications in the pharmaceutical and food industry.
authors: Department of Ophthalmology, Victor Babeș University of Medicine and Pharmacy, Timișoara, Romania.
authors: O
authors: O
authors: Borugă
authors: Department of Food Science, Faculty of Food Processing Technology, Banat's University of Agricultural Sciences and Veterinary Medicine, Timișoara, Romania.
authors: C
authors: C
authors: Jianu
authors: Department of Food Science, Faculty of Food Processing Technology, Banat's University of Agricultural Sciences and Veterinary Medicine, Timișoara, Romania.
authors: C
authors: C
authors: Mişcă
authors: Department of Management, Faculty of Economics and Business Administration, West University of Timișoara, Timișoara, Romania.
authors: I
authors: I
authors: Goleţ
authors: Center for Transplant Immunology, Timișoara County Hospital, Timișoara, Romania.
authors: A T
authors: AT
authors: Gruia
authors: Department of Microbiology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania.
authors: F G
authors: FG
authors: Horhat
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D000081005:Cyclohexane Monoterpenes; D000081007:Cymenes; D008401:Gas Chromatography-Mass Spectrometry; D039821:Monoterpenes / Q000032:analysis; D009822:Oils, Volatile / Q000032:analysis* / Q000494:pharmacology; D013943:Thymol / Q000032:analysis; D046930:Thymus Plant / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D000081005:Cyclohexane Monoterpenes; D000081007:Cymenes; D039821:Monoterpenes; D009822:Oils, Volatile; C007210:4-cymene; D013943:Thymol; C018669:gamma-terpinene
keywords: GC-MS analysis; antimicrobial activity; essential oil; thyme