title: Renal-limited thrombotic microangiopathy and acute interstitial nephritis with a single dose of quinine.
abstract: Quinine has been reported to cause acute kidney injury by various mechanisms. The response to quinine can result in a spectrum of problems ranging from isolated thrombocytopenia to thrombotic microangiopathy (TMA) to disseminated intravascular coagulation. Quinine has also been reported to cause acute interstitial nephritis (AIN). We report an unusual presentation where both of these entities of renal-limited TMA and AIN were precipitated by a single dose of quinine.
authors: Central Northern Adelaide Renal Transplantation Services , Royal Adelaide Hospital , Adelaide , Australia ; Division of Nephrology , Royal Adelaide Hospital , Adelaide, SA , Australia.
authors: Jobert
authors: J
authors: Anjelo
authors: Central Northern Adelaide Renal Transplantation Services , Royal Adelaide Hospital , Adelaide , Australia.
authors: Nitesh
authors: N
authors: Rao
authors: Central Northern Adelaide Renal Transplantation Services , Royal Adelaide Hospital , Adelaide , Australia.
authors: Vinoi G
authors: VG
authors: David
authors: Department of surgical pathology , Royal Adelaide Hospital, SA Pathology , Adelaide, SA , Australia.
authors: Sophia
authors: S
authors: Otto
authors: Central Northern Adelaide Renal Transplantation Services , Royal Adelaide Hospital , Adelaide , Australia.
authors: Graeme
authors: G
authors: Russ
keywords: acute renal failure; interstitial nephritis; quinine; thrombotic microangiopathy