title: IL-33 impacts on the skin barrier by downregulating the expression of filaggrin.
authors: Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
authors: Jenny
authors: J
authors: Seltmann
authors: Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany. Electronic address: roesner.lennart@mh-hannover.de.
authors: Lennart M
authors: LM
authors: Roesner
authors: Plastic Surgery Kröpcke, Hannover, Germany.
authors: Friedrich-Wilhelm
authors: FW
authors: von Hesler
authors: Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, United Kingdom; Centre for Skin Sciences, University of Bradford, Bradford, United Kingdom.
authors: Miriam
authors: M
authors: Wittmann
authors: Division of Immunodermatology and Allergy Research, Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.
authors: Thomas
authors: T
authors: Werfel
mesh_terms: D055516:2S Albumins, Plant / Q000276:immunology / Q000494:pharmacology; D052179:Antigens, Plant / Q000276:immunology / Q000494:pharmacology; D001706:Biopsy; D002118:Calcium / Q000378:metabolism; D016022:Case-Control Studies; D002454:Cell Differentiation / Q000187:drug effects; D003876:Dermatitis, Atopic / Q000235:genetics* / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D000091344:Filaggrin Proteins; D005786:Gene Expression Regulation; D006023:Glycoproteins / Q000276:immunology / Q000494:pharmacology; D006801:Humans; D000067596:Interleukin-33; D015847:Interleukin-4 / Q000276:immunology / Q000378:metabolism / Q000494:pharmacology*; D007378:Interleukins / Q000276:immunology / Q000378:metabolism / Q000494:pharmacology*; D007381:Intermediate Filament Proteins / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000276:immunology; D015603:Keratinocytes / Q000187:drug effects* / Q000276:immunology / Q000473:pathology; D010539:Permeability / Q000187:drug effects; D061251:Primary Cell Culture; D012867:Skin / Q000187:drug effects* / Q000276:immunology / Q000473:pathology
chemical_list: D055516:2S Albumins, Plant; D052179:Antigens, Plant; C500890:Ara h 2 allergen, Arachis hypogaea; C000717249:FLG protein, human; D000091344:Filaggrin Proteins; D006023:Glycoproteins; C506536:IL33 protein, human; C508598:IL4 protein, human; D000067596:Interleukin-33; D007378:Interleukins; D007381:Intermediate Filament Proteins; D015847:Interleukin-4; D002118:Calcium