title: Fish Malodour syndrome in a child.
abstract: Body odour can be a manifestation of several metabolic diseases. Diagnosis may be difficult because the disease is often unknown to the doctor. We present a child observed in a general paediatric clinic for bad body odour after eating fish. Given the suspicion of trimethylaminuria, molecular study of flavin mono-oxygenase 3 gene was requested. A pathogenic mutation and polymorphism were identified, which could explain the complaint. Dietary and hygienic measures were imposed with symptom improvement.
authors: Hospital Pediátrico de Coimbra-Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.
authors: Alexandra
authors: A
authors: Oliveira
authors: Hospital Pediátrico de Coimbra-Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.
authors: Ana
authors: A
authors: Faria
authors: Hospital Pediátrico de Coimbra-Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.
authors: Mónica
authors: M
authors: Oliva
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D004035:Diet Therapy / Q000379:methods; D005260:Female; D006801:Humans; D006920:Hygiene; D008661:Metabolism, Inborn Errors / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D008744:Methylamines / Q000378:metabolism / Q000652:urine*; D009154:Mutation; D010105:Oxygenases / Q000235:genetics / Q000378:metabolism; D011110:Polymorphism, Genetic
chemical_list: D008744:Methylamines; D010105:Oxygenases; C020066:dimethylaniline monooxygenase (N-oxide forming); C005855:trimethyloxamine; C023336:trimethylamine