title: [Pneumomediastinum and cutaneous necrosis in dermatomyositis: Report of one case].
abstract: We report a 37 years old male with a dermatomyositis treated with oral cyclophosphamide. He was admitted to the hospital due to a zone of skin necrosis with purulent exudate, located in the second left toe. A complete blood count showed a leukocyte count of 2,600 cells/mm³. A Chest CAT scan showed a pneumomediastinum with emphysema of adjacent soft tissue. Cyclophosphamide was discontinued and leukocyte count improved. The affected toe was amputated and a chest CAT scan showed a partial resolution of the pneumomediastinum. We discuss and review the pathogenesis, clinical presentation and management of pneumomediastinum and cutaneous necrosis in association with dermatomyositis.
authors: Natalia
authors: N
authors: Gallardo C
authors: Omar
authors: O
authors: Valenzuela L
authors: Sebastián
authors: S
authors: Ibáñez V
mesh_terms: D000328:Adult; D000671:Amputation, Surgical; D003882:Dermatomyositis / Q000150:complications* / Q000628:therapy; D006801:Humans; D008297:Male; D008478:Mediastinal Emphysema / Q000209:etiology* / Q000628:therapy; D009336:Necrosis / Q000473:pathology; D012867:Skin / Q000473:pathology*