title: Parinaud's syndrome - A rare presentation of clinically isolated syndrome.
abstract: We present a 26 year old Pakistani lady with first presentation of a demyelinating event, presenting as Parinaud's syndrome. The video demonstrates a convergence-retraction nystagmus on upgaze and failure of accommodation, and her brain imaging confirms a corresponding pre-tectal contrast enhancing T2 hyperintense lesion suggestive of demyelination. A review of the literature is presented.
authors: Department of Neuroimmunology, UCL Institute of Neurology, and National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG, UK. Electronic address: s.gnanapavan@ucl.ac.uk.
authors: S
authors: S
authors: Gnanapavan
authors: Department of Neuroimmunology, UCL Institute of Neurology, and National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG, UK.
authors: E
authors: E
authors: Sillery
authors: Department of Neuro-ophthalmology, National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG, UK.
authors: J F
authors: JF
authors: Acheson
authors: Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, University College London, WC1N 3BG, UK.
authors: A T
authors: AT
authors: Toosy
keywords: Clinically isolated syndrome; Convergence–retraction nystagmus; Demyelination; Parinaud's syndrome; Pre-tectal lesion; Vertical diplopia