title: Laparoscopic sleeve gastrectomy effects on overactive bladder symptoms.
abstract: BACKGROUND
  Morbidly obese patients may experience lower urinary tract symptoms. However, most studies focus only on urinary incontinence, with little regard to other symptoms as those suggestive for overactive bladder (OAB) syndrome. Laparoscopic sleeve gastrectomy (LSG) is commonly used to treat obesity; this procedure is effective, safe, and capable of reducing the impact of comorbidities associated with severe increase in body weight. Therefore, we investigated if LSG improves OAB symptoms in morbidly obese patients.
  
  
  METHODS
  We prospectively recruited 120 morbidly obese patients (60 men and 60 women), evaluated by history taking, comorbidity assessment, physical examination, urinalysis and urine culture, renal and pelvic ultrasound, a 3-d voiding diary, and the OAB questionnaire short form. Outcomes of these investigations were assessed 7 d before and 180 d after LSG was performed. Controls were obese individuals (60 men and 60 women) from an LSG waiting list.
  
  
  RESULTS
  Symptoms of OAB were common in the morbidly obese cohort, affecting more women than men. Compared with untreated patients, patients treated with LSG had significantly reduced body mass index 180 d postoperatively; this outcome was associated with improvement in OAB symptoms, whereas no change occurred in untreated controls.
  
  
  CONCLUSIONS
  OAB symptoms improve in morbidly obese patients successfully treated by LSG.
authors: Department of Sciences and Medico-Surgical Biotechnologies, Urology Unit, ICOT, Sapienza University of Rome, Latina, Italy; Uroresearch Association, Non Profit Association for Basic, Clinical and Surgical Research in Urology, Latina, Italy.
authors: Giovanni
authors: G
authors: Palleschi
authors: Department of Sciences and Medico-Surgical Biotechnologies, Urology Unit, ICOT, Sapienza University of Rome, Latina, Italy; Uroresearch Association, Non Profit Association for Basic, Clinical and Surgical Research in Urology, Latina, Italy. Electronic address: antopast@hotmail.com.
authors: Antonio Luigi
authors: AL
authors: Pastore
authors: Centre of Excellence for Bariatric and Metabolic Surgery, Department of Sciences and Medico-Surgical Biotechnologies, ICOT, Sapienza University of Rome, Latina, Italy.
authors: Mario
authors: M
authors: Rizzello
authors: Centre of Excellence for Bariatric and Metabolic Surgery, Department of Sciences and Medico-Surgical Biotechnologies, ICOT, Sapienza University of Rome, Latina, Italy.
authors: Giuseppe
authors: G
authors: Cavallaro
authors: Centre of Excellence for Bariatric and Metabolic Surgery, Department of Sciences and Medico-Surgical Biotechnologies, ICOT, Sapienza University of Rome, Latina, Italy.
authors: Gianfranco
authors: G
authors: Silecchia
authors: Department of Sciences and Medico-Surgical Biotechnologies, Urology Unit, ICOT, Sapienza University of Rome, Latina, Italy; Uroresearch Association, Non Profit Association for Basic, Clinical and Surgical Research in Urology, Latina, Italy.
authors: Antonio
authors: A
authors: Carbone
mesh_terms: D000328:Adult; D050110:Bariatric Surgery; D005260:Female; D005743:Gastrectomy; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications* / Q000601:surgery; D015995:Prevalence; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D053201:Urinary Bladder, Overactive / Q000453:epidemiology* / Q000209:etiology
keywords: Body mass index; Obesity; Overactive bladder; Sleeve gastrectomy