title: Conservation of Helicity in a Chiral Pyrrol-2-yl Schiff-Base Ligand and Its Transition Metal Complexes.
abstract: Tetradentate enantiopure Schiff-base ligand (R,R) and (S,S)-bis(pyrrol-2-ylmethyleneamine)-cyclohexane (H2L) and its five transition metal complexes with Ni(II), Cu(II), Zn(II), Pd(II), and Pt(II) were synthesized. Their structural properties, in particular, the ligand chirality, coordination topology, and the resulting helicity in solution, were investigated by using IR, vibrational circular dichroism (VCD), UV-vis, and electronic circular dichroism (ECD) spectroscopies, complemented with density functional theory calculations. Conformational searches and the associated spectral simulations for the ligands and the complexes were performed at the B3LYP/Gen level. Comparison of the experimental and theoretical IR and VCD spectral signatures of these complexes reveal that the Zn complex takes on a dinuclear, distorted tetrahedral coordination topology around the metal centers, whereas the other four metal complexes adopt the mononuclear, distorted square-planar coordination arrangement in solution. The helicity of all systems studied was identified to be M with the (R,R) ligand and P with the (S,S) ligand, dictated by the ligand chirality and the strong preference for the chair configuration by the cyclohexane moiety. Furthermore, the resulting helicity was found to dominate the ECD spectral features, even though the helicity-determining angles are close to zero for the nearly square-planar metal complexes. The related VCD spectral features are sensitive to both helicity of the complex and the chirality of the ligands, as well as the coordination topology. The simulated ECD spectra for the P and M helicity of the [Zn-(R,R)-L]2 complex shows almost mirror-imaged ECD spectral features, whereas very similar ECD spectra were recently reported for the P- and M-dinuclear Mn complexes with a di-μ-oxo dimetal core as a linker. We highlight the advantages of utilizing multiple chiroptical techniques and theoretical spectral simulations to correlate chiroptical spectral features with multiple chirality and helicity elements in the systems.
authors: Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.
authors: Zahra
authors: Z
authors: Dezhahang
authors: Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.
authors: Mohammad Reza
authors: MR
authors: Poopari
authors: Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.
authors: Joseph
authors: J
authors: Cheramy
authors: Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada.
authors: Yunjie
authors: Y
authors: Xu