title: Modular Approach to Reductive C(sp2)-H and C(sp3)-H Silylation of Carboxylic Acid Derivatives through Single-Pot, Sequential Transition Metal Catalysis.
abstract: We report a modular approach to catalytic reductive Csp2-H and Csp3-H silylation of carboxylic acid derivatives encompassing esters, ketones, and aldehydes. Choice of either an Ir(I)/Rh(I) or Rh(I)/Rh(I) sequence leads to either exhaustive reductive ester or reductive ketone/aldehyde silylation, respectively. Notably, a catalyst-controlled direct formation of doubly reduced silyl ethers is presented, specifically via Ir-catalyzed exhaustive hydrosilylation. The resulting silyl ethers undergo Csp2-H and benzylic Csp3-H silylation in a single vessel.
authors: Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, Texas 76019, United States.
authors: Yuanda
authors: Y
authors: Hua
authors: Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, Texas 76019, United States.
authors: Seongjeong
authors: S
authors: Jung
authors: Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, Texas 76019, United States.
authors: James
authors: J
authors: Roh
authors: Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, Texas 76019, United States.
authors: Junha
authors: J
authors: Jeon