title: Assessment of acid-base balance at birth in newborns from diabetic mothers.
abstract: Newborns from diabetic mothers are more frequently born prematurely, large for the gestational age, with difficult respiratory adaptation and risk of RDS (respiratory distress syndrome) and, subsequently, exposed to a higher risk of perinatal distress, hypoxia, metabolic stress and hematologic alterations. Comparing the status at birth of 120 newborns from mothers with diabetes, with 120 controls from uncomplicated pregnancies, over a period of 4 years, in a specialized tertiary center, no significant differences in the immediate outcome of such newborns and similar incidence of hypoxia at birth were shown, as illustrated by the parameters of the acid-base balance (cord pH, BE and HCO3). However, there are significant differences in the route of delivery, with a predominance of C-section deliveries in the diabetic group (4 out of every 5 cases), which might be an important contribution to the relative good status of these newborns at birth. Although balanced at birth, the newborns from diabetic mothers need intensive monitoring and care in the subsequent hours after birth, for important risks such as hypoglycemic episodes.
authors: "Dr. I. Cantacuzino" Clinical Hospital, Bucharest, Romania.
authors: A
authors: A
authors: Stanescu
authors: "Carol Davila" University of Medicine and Pharmacy, Bucharest; Neonatology Department, "Polizu" Clinical Hospital, Bucharest; "Alfred Rusescu" Institute for Mother and Child Care, Bucharest, Romania.
authors: S M
authors: SM
authors: Stoicescu
mesh_terms: D000136:Acid-Base Equilibrium; D016640:Diabetes, Gestational; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000517:prevention & control*; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011446:Prospective Studies
keywords: IDM (infant from diabetic mother); cord blood sampling; diabetes mellitus; pregnancy