title: A Sporadic Case of Advanced Metastatic Cholangiocarcinoma in a Child: A Case Report and Review of Literature.
abstract: Cholangiocarcinoma (CC) is a malignancy of the biliary tract that commonly presents in the seventh decade of life, but is extremely rare in children. We report on a sporadic case of malignant CC in an 11-year-old female. Originally presenting with dyspnea, chest x-ray identified multiple pulmonary metastases, and various imaging modalities revealed diffuse disease spread throughout the liver and lungs. Following pathologic diagnosis of CC, aggressive treatment was initiated with a dramatic initial response to chemotherapy, however, as often occurs with advanced disease in adults, this patient ultimately succumbed to the disease.
authors: *Cancer Center Departments of †Pharmacology and Neuroscience ‡Pathology §Pediatrics, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX.
authors: Connor
authors: C
authors: Hall
authors: Viviane
authors: V
authors: Mamlok
authors: Ihsan
authors: I
authors: Al-Khalil
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001650:Bile Duct Neoplasms / Q000188:drug therapy / Q000473:pathology*; D001653:Bile Ducts, Intrahepatic / Q000473:pathology*; D002648:Child; D018281:Cholangiocarcinoma / Q000188:drug therapy / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans