title: Comparative Evaluation of Two PCR-Based Methods for Detection of Methicillin-Resistant Staphylococcus aureus (MRSA): Xpert MRSA Gen 3 and BD-Max MRSA XT.
abstract: We compared two walk-away molecular diagnostic assays, the GeneXpert MRSA Gen 3 assay and the BD-Max MRSA XT assay. A total of 119 prospective swabs and 36 culture-positive samples were tested. Xpert MRSA Gen 3 had sensitivity of 95.7% and specificity of 100% versus 87.5% and 97.1% for BD-Max. The difference in agreement with the enriched culture results was significantly in favor of the Xpert assay (P < 0.02, McNemar nonparametric text).
authors: Infection Control Team, Hôpital Raymond Poincaré, AP-HP, Garches, France Microbiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France.
authors: Margaux
authors: M
authors: Lepainteur
authors: Microbiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France.
authors: Sandrine
authors: S
authors: Delattre
authors: Microbiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France.
authors: Sophie
authors: S
authors: Cozza
authors: Infection Control Team, Hôpital Raymond Poincaré, AP-HP, Garches, France Microbiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France.
authors: Christine
authors: C
authors: Lawrence
authors: Microbiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France INSERM U1173, UFR Simone Veil, Versailles-Saint-Quentin University, Saint-Quentin en Yvelines, France.
authors: Anne-Laure
authors: AL
authors: Roux
authors: Microbiology Laboratory, Hôpital Raymond Poincaré, AP-HP, Garches, France INSERM U1173, UFR Simone Veil, Versailles-Saint-Quentin University, Saint-Quentin en Yvelines, France martin.rottman@rpc.aphp.fr.
authors: Martin
authors: http://orcid.org/0000-0001-5953-3344
authors: M
authors: Rottman
mesh_terms: D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000235:genetics*; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009296:Nasal Cavity / Q000382:microbiology; D016133:Polymerase Chain Reaction / Q000379:methods*; D011446:Prospective Studies; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000382:microbiology