title: Treatment of pediatric spinal tuberculosis abscess with percutaneous drainage and low-dose local antituberculous therapy: a preliminary report.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the outcomes of computed tomography (CT) guidance using percutaneous catheter with low-dose drainage local chemotherapy (modified PCD) and antituberculous therapy (ATT) for the treatment of spinal tuberculosis in children.
  
  
  METHODS
  Twenty-seven children suffering from spinal tuberculosis were treated with modified PCD and ATT in our institute from 2002 to 2012. We describe our treatment, which involves CT-guided percutaneous puncture and local chemotherapy (continuous low-dose (20 mL) irrigation). The patients were evaluated based on the Frankel scoring system, the kyphotic Cobb angle, and the erythrocyte sedimentation rate (ESR).
  
  
  RESULTS
  All patients were followed up for an average of 31.00 ± 13.94 months. No sinus formation was detected. All patients responded well to this treatment. The ESR values were decreased to normal at last follow-up. The neurological functions show significant improvement after operation. Preoperatively, the kyphotic angle was 22.89 ± 7.06°, and it was measured as 21.19 ± 8.73° at the last visit.
  
  
  CONCLUSIONS
  Our results showed that percutaneous intubation and low-dose irrigation under CT guidance (modified percutaneous catheter drainage (MPCD)) and ATT are easy, safe, efficient, and less invasive methods for the treatment of spinal tuberculosis in children.
authors: Department of Spine Surgery, Xiangya Hospital of Central South University, Xiangya Road 87, Changsha, China.
authors: Xin Hua
authors: XH
authors: Yin
authors: Hong Qi
authors: HQ
authors: Zhang
authors: Xiong Ke
authors: XK
authors: Hu
authors: Jin Song
authors: JS
authors: Li
authors: Yong
authors: Y
authors: Chen
authors: Ke Feng
authors: KF
authors: Zeng
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000209:etiology / Q000601:surgery; D000995:Antitubercular Agents / Q000627:therapeutic use*; D002404:Catheterization / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D015898:Tomography Scanners, X-Ray Computed; D014399:Tuberculosis, Spinal / Q000150:complications / Q000188:drug therapy / Q000601:surgery
chemical_list: D000995:Antitubercular Agents