title: Effect of Anti-Sticking Nanostructured Surface Coating on Minimally Invasive Electrosurgical Device in Brain.
abstract: The purpose of the present study was to examine the extent of thermal injury in the brain after the use of a minimally invasive electrosurgical device with a nanostructured copper-doped diamond-like carbon (DLC-Cu) surface coating. To effectively utilize an electrosurgical device in clinical surgery, it is important to decrease the thermal injury to the adjacent tissues. The surface characteristics and morphology of DLC-Cu thin film was evaluated using a contact angle goniometer, scanning electron microscopy, and atomic force microscopy. Three-dimensional biomedical brain models were reconstructed using magnetic resonance images to simulate the electrosurgical procedure. Results indicated that the temperature was reduced significantly when a minimally invasive electrosurgical device with a DLC-Cu thin film coating (DLC-Cu-SS) was used. Temperatures decreased with the use of devices with increasing film thickness. Thermographic data revealed that surgical temperatures in an animal model were significantly lower with the DLC-Cu-SS electrosurgical device compared to an untreated device. Furthermore, the DLC-Cu-SS device created a relatively small region of injury and lateral thermal range. As described above, the biomedical nanostructured film reduced excessive thermal injury with the use of a minimally invasive electrosurgical device in the brain.
authors: Graduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical University, Taipei, 110, Taiwan. chytmu@gmail.com.|Research Center for Biomedical Devices and Prototyping Production, Taipei Medical University, Taipei, Taiwan. chytmu@gmail.com.|Research Center for Biomedical Implants and Microsurgery Devices, Taipei Medical University, Taipei, 110, Taiwan. chytmu@gmail.com.
authors: Han-Yi
authors: HY
authors: Cheng
authors: Graduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical University, Taipei, 110, Taiwan.|Research Center for Biomedical Devices and Prototyping Production, Taipei Medical University, Taipei, Taiwan.|Research Center for Biomedical Implants and Microsurgery Devices, Taipei Medical University, Taipei, 110, Taiwan.|Department of Dentistry, Taipei Medical University-Shuang Ho Hospital, Taipei, 235, Taiwan.
authors: Keng-Liang
authors: KL
authors: Ou
authors: Graduate Institute of Biomedical Materials and Tissue Engineering, Taipei Medical University, Taipei, 110, Taiwan.|Research Center for Biomedical Devices and Prototyping Production, Taipei Medical University, Taipei, Taiwan.|Department of Dentistry, Taipei Medical University-Shuang Ho Hospital, Taipei, 235, Taiwan.|School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan.
authors: Hsi-Jen
authors: HJ
authors: Chiang
authors: Research Center for Biomedical Devices and Prototyping Production, Taipei Medical University, Taipei, Taiwan. lisa@tmu.edu.tw.|School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan. lisa@tmu.edu.tw.
authors: Li-Hsiang
authors: LH
authors: Lin
mesh_terms: D000818:Animals; D001921:Brain / Q000601:surgery*; D004598:Electrosurgery / Q000295:instrumentation* / Q000379:methods; D008855:Microscopy, Electron, Scanning; D008954:Models, Biological; D049329:Nanostructures; D019635:Neurosurgical Procedures / Q000295:instrumentation* / Q000379:methods; D051381:Rats; D017207:Rats, Sprague-Dawley; D013499:Surface Properties
keywords: Electrosurgical device; Nanostructured film; Thermal injury