title: Danish national sedation strategy. Targeted therapy of discomfort associated with critical illness. Danish Society of Intensive Care Medicine (DSIT) and the Danish Society of Anesthesiology and Intensive Care Medicine (DASAIM).
abstract: Sedation of critically ill patients undergoing mechanical ventilation should be minimized or completely avoided. Only in selected situations is sedation indicated as first line therapy (increased intracranial pressure or therapeutic hypothermia). The critical care physicians primary objective should be to focus on the reversible causes of agitation, such as: pain, anxiety, delirium, dyspnea, withdrawal symptoms, sleep or gastrointestinal symptoms. If sedation is used a validated sedation scale is recommended. On a daily basis sedation should be interrupted and only restarted after a thorough search for reversible causes of discomfort and stress.
authors: Department of Intensive Care, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark. lise.fonsmark@rh.regionh.dk.
authors: Lise
authors: L
authors: Fonsmark
authors: Lars
authors: L
authors: Hein
authors: Helle
authors: H
authors: Nibroe
authors: Helle
authors: H
authors: Bundgaard
authors: Inge
authors: I
authors: de Haas
authors: Susanne
authors: S
authors: Iversen
authors: Thomas
authors: T
authors: Strøm
mesh_terms: D000776:Anesthesiology / Q000379:methods / Q000592:standards*; D016292:Procedural Sedation / Q000379:methods / Q000592:standards*; D003422:Critical Care / Q000592:standards; D016638:Critical Illness; D003718:Denmark; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage* / Q000009:adverse effects; D007362:Intensive Care Units / Q000592:standards; D008297:Male; D017063:Outcome Assessment, Health Care; D010146:Pain / Q000188:drug therapy* / Q000503:physiopathology; D017410:Practice Guidelines as Topic / Q000592:standards*; D012121:Respiration, Artificial / Q000379:methods; D018570:Risk Assessment; D012955:Societies, Medical / Q000592:standards
chemical_list: D006993:Hypnotics and Sedatives