title: Microarray analysis of differentially expressed genes in the liver between Bai'er layers and broilers.
abstract: In this study, we profiled gene expression in chicken liver and screened differentially expressed genes in the Bai'er layers and fat line broilers. Birds were derived from the 14th generation of Northeast Agricultural University fat broiler lines and Bai'er layers. Chicken genome arrays were used to screen differentially expressed genes in liver tissue from the Bai'er layers and fat line broilers. We screened 671 differentially expressed genes between broilers and layers at the ages of 2 and 4 weeks. We observed enrichment of a series of significant pathways, including the mitogen-activated protein kinase signaling pathway, cell cycle, mammalian target of rapamycin signaling pathway, and p53 signaling pathway. At 2 and 4 weeks, 94 shared differentially expressed genes were observed. We speculated that these genes regulate chicken lipid metabolism.
authors: Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin, China.
authors: Q-G
authors: QG
authors: Wang
authors: Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin, China.
authors: H-F
authors: HF
authors: Zhang
authors: Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin, China.
authors: S-Z
authors: SZ
authors: Wang
authors: Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin, China.
authors: G L
authors: GL
authors: Gao
authors: Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin, China.
authors: L
authors: L
authors: Leng
authors: Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin, China.
authors: W
authors: W
authors: Na
authors: Key Laboratory of Chicken Genetics and Breeding, Ministry of Agriculture, Harbin, China lihui@neau.edu.cn.
authors: H
authors: H
authors: Li
mesh_terms: D000367:Age Factors; D000818:Animals; D002645:Chickens / Q000145:classification / Q000235:genetics*; D020869:Gene Expression Profiling / Q000379:methods*; D050356:Lipid Metabolism / Q000235:genetics; D008099:Liver / Q000378:metabolism*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods*; D015398:Signal Transduction / Q000235:genetics; D013045:Species Specificity