title: Diffuse alveolar hemorrhage in a patient with acute poststreptococcal glomerulonephritis caused by impetigo.
abstract: We herein report a case of pulmonary renal syndrome with nephritis in a 17-year-old boy with diffuse alveolar hemorrhage (DAH) associated with acute poststreptococcal glomerulonephritis (APSGN). The patient exhibited hemoptysis two weeks after developing impetigo, and DAH was diagnosed on bronchoscopy. Respiratory failure progressed, and high-dose methylprednisolone therapy was administered; the respiratory failure regressed immediately after the onset of therapy. Streptococcus pyogenes was detected in an impetigo culture, and, together with the results of the renal biopsy, a diagnosis of APSGN was made. This case demonstrates the effects of high-dose methylprednisolone therapy in improving respiratory failure.
authors: Department of Internal Medicine, Division of Respiratory Medicine, Jikei University School of Medicine, Kashiwa Hospital, Japan.
authors: Masahiro
authors: M
authors: Yoshida
authors: Hideaki
authors: H
authors: Yamakawa
authors: Masami
authors: M
authors: Yabe
authors: Takeo
authors: T
authors: Ishikawa
authors: Masamichi
authors: M
authors: Takagi
authors: Kei
authors: K
authors: Matsumoto
authors: Akihiko
authors: A
authors: Hamaguchi
authors: Makoto
authors: M
authors: Ogura
authors: Kazuyoshi
authors: K
authors: Kuwano
mesh_terms: D000293:Adolescent; D005921:Glomerulonephritis / Q000209:etiology / Q000382:microbiology* / Q000473:pathology; D006469:Hemoptysis / Q000150:complications / Q000382:microbiology* / Q000473:pathology; D006470:Hemorrhage / Q000209:etiology / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D007169:Impetigo / Q000150:complications / Q000382:microbiology* / Q000473:pathology; D008171:Lung Diseases / Q000209:etiology / Q000382:microbiology* / Q000473:pathology; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D012131:Respiratory Insufficiency / Q000188:drug therapy* / Q000209:etiology; D013297:Streptococcus pyogenes / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D008775:Methylprednisolone