title: Mitochondria-targeted fluorescent thermometer monitors intracellular temperature gradient.
abstract: Intracellular thermometry at the microscopic level is currently a hot topic. Herein we describe a small molecule fluorescent thermometer targeting mitochondria (Mito thermo yellow). Mito thermo yellow successfully demonstrates the ability to monitor the intracellular temperature gradient, generated by exogenous heating, in various cells.
authors: Department of Chemistry and MedChem Program of Life Sciences Institute, National University of Singapore, 117543, Singapore. chmcyt@nus.edu.sg.
authors: Satoshi
authors: S
authors: Arai
authors: Madoka
authors: M
authors: Suzuki
authors: Sung-Jin
authors: SJ
authors: Park
authors: Jung Sun
authors: JS
authors: Yoo
authors: Lu
authors: L
authors: Wang
authors: Nam-Young
authors: NY
authors: Kang
authors: Hyung-Ho
authors: HH
authors: Ha
authors: Young-Tae
authors: YT
authors: Chang
mesh_terms: D016475:3T3 Cells; D000818:Animals; D002460:Cell Line; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D051379:Mice; D008928:Mitochondria / Q000737:chemistry*; D015394:Molecular Structure; D013696:Temperature; D062125:Thermometry / Q000379:methods*; D014966:Xanthenes / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; C000604778:Mito thermo yellow; D014966:Xanthenes