title: New telemetry device for the measurement of gastrointestinal motility in rats and comparison with standard equipment.
abstract: To perform stress-free recording of gastrointestinal motility in rats with strain gauge transducers, telemetry equipment had to be developed. We developed, programmed, and tested a new telemetry device that records gastrointestinal motility in freely moving rats using strain gauge transducers. The device can collect and transmit data in freely moving rats. Data are received and stored for later analysis with a regular PC. Linear calibration curves were obtained for the strain gauge transducers used. We compared data obtained with the new telemetry device with data gathered with standard equipment and could not find any statistically significant difference. Wired gastric and colonic contraction frequencies were 4.6 ± 0.3 per minute and 1.5 ± 0.3 per minute, whereas telemetric contraction frequencies were 4.4 ± 0.1 per minute and 1.25 ± 0.1 per minute. The new telemetry device is a very useful tool for the measurement of gastrointestinal motility in rats.
authors: University Hospital Tübingen, Tübingen, Germany.
authors: Tobias
authors: T
authors: Meile
authors: Derek
authors: D
authors: Zieker
authors: Alfred
authors: A
authors: Königsrainer
authors: Jörg
authors: J
authors: Glatzle
mesh_terms: D000818:Animals; D004867:Equipment Design; D005769:Gastrointestinal Motility / Q000502:physiology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013686:Telemetry / Q000295:instrumentation*; D014159:Transducers
keywords: Intestine; Motility; Rat; Strain gauge transducer; Telemetry