title: One-Pot Synthesis of 2,5-Diaryl 1,3,4-Oxadiazoles via Di-tert-butyl Peroxide Promoted N-Acylation of Aryl Tetrazoles with Aldehydes.
abstract: A metal- and base-free protocol for one-pot synthesis of 2,5-diaryl 1,3,4-oxadiazoles via a radical-promoted cross-dehydrogenative coupling strategy was developed. This reaction involved the N-acylation of aryl tetrazoles with aryl aldehydes, followed by thermal rearrangement. A wide range of aryl tetrazoles and aryl aldehydes survived the reaction conditions to deliver the corresponding products in moderate to good yields.
authors: Liang
authors: L
authors: Wang
authors: Jing
authors: J
authors: Cao
authors: Qun
authors: Q
authors: Chen
authors: Mingyang
authors: M
authors: He
mesh_terms: D000215:Acylation; D000447:Aldehydes / Q000737:chemistry*; D015394:Molecular Structure; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000737:chemistry; D010545:Peroxides / Q000737:chemistry*; D013777:Tetrazoles / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D010069:Oxadiazoles; D010545:Peroxides; D013777:Tetrazoles; C111570:di-tert-butyl peroxide; C583463:1,3,4-oxadiazole