title: The impact of epidemics of vaccine-preventable disease on vaccine uptake: lessons from the 2011-2012 US pertussis epidemic.
abstract: Conventional wisdom suggests that if there is a vaccine that is effective in preventing a disease, vaccine uptake will increase when the disease risk is high. Recent evidence, however, suggests that this may not always be the case. In a study we conducted in Washington State, we found no population-level increase in pertussis vaccination of infants during a pertussis epidemic. In this paper, we aim to review what is known about the history of vaccine uptake during epidemics of vaccine-preventable disease, the challenges facing public health campaigns responding to these epidemics, and how the effect of a vaccine-preventable disease epidemic on vaccine uptake can be studied.
authors: Seattle Children's Research Institute, Seattle, WA, USA.
authors: Elizabeth R
authors: ER
authors: Wolf
authors: Ali
authors: A
authors: Rowhani-Rahbar
authors: Douglas J
authors: DJ
authors: Opel
mesh_terms: D058872:Epidemics; D006801:Humans; D010567:Pertussis Vaccine / Q000008:administration & dosage* / Q000276:immunology*; D014611:Vaccination / Q000706:statistics & numerical data*; D014861:Washington / Q000453:epidemiology; D014917:Whooping Cough / Q000453:epidemiology* / Q000517:prevention & control*
chemical_list: D010567:Pertussis Vaccine
keywords: epidemics; epidemiological study characteristics; health communication; public health; vaccination