title: Usefulness of intraoperative observation using a fluorescence imaging instrument for patients with nonocclusive mesenteric ischemia.
abstract: The authors evaluated the usefulness of intraoperative photodynamic eye (PDE) observation in patients with nonocclusive mesenteric ischemia (NOMI). Between February 2012 and July 2013, 6 patients who had undergone emergency surgery for NOMI were enrolled. Intraoperative PDE observation was performed to decide the adequate length of bowel resection including all skipped dark spots, which could not be detected as ongoing mucosal ischemic changes under visible light observation. All ongoing mucosal ischemic changes were easily detected as dark spots using PDE observation in all 6 patients. The mean length of adequate ileal resection (92 ± 48 cm) was significantly longer than that of ischemic ileum (85 ± 50 cm) (mean ± SD) (P = 0.043). After resection of an adequate length of bowel, all the patients had a good course until discharge without incidents due to residual bowel ischemia, except for 1patient who died. PDE observation is useful for deciding the adequate length of bowel to resect, including ongoing mucosal ischemic changes that cannot be detected under visible light observation. In patients with NOMI, resection of an adequate length of bowel is necessary to prevent postoperative incidents due to residual bowel ischemia.
authors: 1 Department of Gastroenterological Surgery and.
authors: Mitsuru
authors: M
authors: Ishizuka
authors: Hitoshi
authors: H
authors: Nagata
authors: Kazutoshi
authors: K
authors: Takagi
authors: Yoshimi
authors: Y
authors: Iwasaki
authors: Hidetsugu
authors: H
authors: Yamagishi
authors: Genki
authors: G
authors: Tanaka
authors: Keiichi
authors: K
authors: Kubota
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003952:Diagnostic Imaging / Q000295:instrumentation*; D004630:Emergencies; D005260:Female; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000008:administration & dosage; D006801:Humans; D007208:Indocyanine Green / Q000008:administration & dosage; D007430:Intraoperative Care; D008297:Male; D065666:Mesenteric Ischemia / Q000601:surgery*; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D005456:Fluorescent Dyes; D007208:Indocyanine Green
keywords: Dark spot; Fluorescence; Indocyanine green; Nonocclusive mesenteric ischemia; Photodynamic eye