title: Diagnosis of Retrobulbar Round Cell Neoplasia in a Macaroni Penguin ( Eudyptes chrysolophus ) Through Use of Computed Tomography.
abstract: A 25-year-old female macaroni penguin (Eudyptes chrysolophus) was diagnosed with exophthalmos secondary to retrobulbar neoplasia through use of computed tomography (CT). Histopathologic examination of the mass supported a diagnosis of malignant round cell neoplasia. Immunohistochemical (IHC) labeling was applied to determine cell origin; the neoplastic cells did not label with T-cell marker CD3 or B-cell marker BLA.36 and could not be further characterized. The scleral ossicles precluded evaluation of the retrobulbar space by ultrasonography; therefore, CT scanning is recommended for examination of intraorbital structures in penguin and other avian species.
authors: Sarah J
authors: SJ
authors: Woodhouse
authors: Michelle
authors: M
authors: Rose
authors: Danielle R
authors: DR
authors: Desjardins
authors: Dalen W
authors: DW
authors: Agnew
mesh_terms: D000818:Animals; D000836:Animals, Zoo; D001715:Bird Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D046429:Spheniscidae; D014057:Tomography, X-Ray Computed / Q000662:veterinary*
keywords: Eudyptes chrysolophus; avian; computed tomography; exophthalmos; immunohistochemistry; macaroni penguin; retrobulbar mass; scleral ossicles