title: Divergent construction of pyrazoles via Michael addition of N-arylhydrazones to 1,2-diaza-1,3-dienes.
abstract: The base (NaH)-promoted Michael addition of N-arylhydrazones (AHs) with 1,2-diaza-1,3-dienes (DDs) produces unprecedented β-azohydrazone adducts. Strategically, the use of AHs as acyl anion equivalents (d(1) synthon) and DDs as α-electrophiles (a(2) synthon) of carbonyl compounds open the way to two important classes of pyrazole compounds.
authors: Department of Biomolecular Sciences, Section of Organic Chemistry and Organic Natural Compounds, University of Urbino "Carlo Bo", Via I Maggetti 24, 61029 Urbino PU, Italy.
authors: Serena
authors: S
authors: Mantenuto
authors: Department of Biomolecular Sciences, Section of Organic Chemistry and Organic Natural Compounds, University of Urbino "Carlo Bo", Via I Maggetti 24, 61029 Urbino PU, Italy.
authors: Fabio
authors: F
authors: Mantellini
authors: Department of Biomolecular Sciences, Section of Organic Chemistry and Organic Natural Compounds, University of Urbino "Carlo Bo", Via I Maggetti 24, 61029 Urbino PU, Italy.
authors: Gianfranco
authors: G
authors: Favi
authors: Department of Biomolecular Sciences, Section of Organic Chemistry and Organic Natural Compounds, University of Urbino "Carlo Bo", Via I Maggetti 24, 61029 Urbino PU, Italy.
authors: Orazio A
authors: OA
authors: Attanasi
mesh_terms: D000466:Alkadienes / Q000737:chemistry*; D001372:Aza Compounds / Q000737:chemistry*; D006835:Hydrazones / Q000737:chemistry*; D015394:Molecular Structure; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000466:Alkadienes; D001372:Aza Compounds; D006835:Hydrazones; D011720:Pyrazoles