title: Antihyperglucolipidaemic and anticarbonyl stress properties in green, yellow and red sweet bell peppers (Capsicum annuum L.).
abstract: Effect of aqueous methanol extract of different colour sweet bell peppers (Capsicum annuum L.) on parameters of diabesity and carbonyl stress was analysed in vitro. Yellow pepper displayed significantly (p < 0.001) higher intestinal α-glucosidase inhibitory activity than green and red pepper. Porcine pancreatic lipase inhibitory activity was significantly (p < 0.01) high in yellow and red pepper than in green pepper. Green and red pepper inhibited vesperlysine-type advanced glycation end products (AGEs) more potently than yellow pepper; however, pentosidine-type AGEs were similarly inhibited by all three peppers. Yellow and red pepper inhibited lipid peroxidation more potently (p < 0.01) than green pepper. Total polyphenol content and free radicals scavenging activities in yellow and red bell peppers were higher than in green pepper. Total flavonoid content was high in green pepper than that present in yellow and red peppers. Green pepper displayed presence of proanthocyanins; however, oligomeric anthocyanins were detected in yellow and red peppers.
authors: a Metabolic Disorders & Oxidative Stress Research Laboratory, Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology , Hyderabad 500007 , India.
authors: Srishti
authors: S
authors: Shukla
authors: a Metabolic Disorders & Oxidative Stress Research Laboratory, Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology , Hyderabad 500007 , India.
authors: Dommati Anand
authors: DA
authors: Kumar
authors: a Metabolic Disorders & Oxidative Stress Research Laboratory, Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology , Hyderabad 500007 , India.
authors: Sanga Venkata
authors: SV
authors: Anusha
authors: a Metabolic Disorders & Oxidative Stress Research Laboratory, Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology , Hyderabad 500007 , India.|b Academy of Scientific and Innovative Research (AcSIR), CSIR-Indian Institute of Chemical Technology , Hyderabad 500007 , India.
authors: Ashok Kumar
authors: AK
authors: Tiwari
mesh_terms: D000818:Animals; D002212:Capsicum / Q000737:chemistry*; D003116:Color; D016166:Free Radical Scavengers / Q000494:pharmacology; D017127:Glycation End Products, Advanced / Q000037:antagonists & inhibitors; D006017:Glycolipids / Q000037:antagonists & inhibitors / Q000097:blood*; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D020799:Pancrelipase / Q000037:antagonists & inhibitors; D010936:Plant Extracts / Q000494:pharmacology*; D059808:Polyphenols / Q000032:analysis; D050050:Protein Carbonylation / Q000187:drug effects*; D013552:Swine
chemical_list: D016166:Free Radical Scavengers; D017127:Glycation End Products, Advanced; D006017:Glycolipids; D000960:Hypolipidemic Agents; D010936:Plant Extracts; D059808:Polyphenols; D020799:Pancrelipase
keywords: Capsicum annuum; advanced glycation end products; diabesity; lipid peroxidation; pancreatic lipase inhibition; sweet bell pepper; α-glucosidase inhibition