title: Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media.
abstract: A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH˙) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH˙/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.
authors: Radio-Redox-Response Research Team, Advanced Particle Radiation Biology Research Program, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), Inage-ku, Chiba 263-8555, Japan. nakanis@nirs.go.jp.
authors: Ikuo
authors: I
authors: Nakanishi
authors: Kei
authors: K
authors: Ohkubo
authors: Kohei
authors: K
authors: Imai
authors: Masato
authors: M
authors: Kamibayashi
authors: Yasuo
authors: Y
authors: Yoshihashi
authors: Ken-ichiro
authors: K
authors: Matsumoto
authors: Kiyoshi
authors: K
authors: Fukuhara
authors: Katsuhide
authors: K
authors: Terada
authors: Shinobu
authors: S
authors: Itoh
authors: Toshihiko
authors: T
authors: Ozawa
authors: Shunichi
authors: S
authors: Fukuzumi
mesh_terms: D001205:Ascorbic Acid / Q000737:chemistry; D001713:Biphenyl Compounds / Q000737:chemistry*; D002839:Chromans / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry*; D005609:Free Radicals / Q000737:chemistry*; D010851:Picrates / Q000737:chemistry*; D012995:Solubility; D014867:Water / Q000737:chemistry; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D001713:Biphenyl Compounds; D002839:Chromans; D016166:Free Radical Scavengers; D005609:Free Radicals; D010851:Picrates; D047392:beta-Cyclodextrins; D014867:Water; C004931:1,1-diphenyl-2-picrylhydrazyl; C031215:betadex; D001205:Ascorbic Acid; C010643:6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid