title: Shed NKG2D ligand boosts NK cell immunity.
abstract: Ligands for natural killer (NK) cell activating receptors can be released from tumor cells and are believed to promote tumor growth by acting as decoys for effector lymphocytes. In a recent paper published in Science, Deng et al. report another scenario in which a shed form of the MULT1 mouse NKG2D ligand boosts NK cell functions.
authors: 1] Centre d'Immunologie de Marseille-Luminy, UM2 Aix-Marseille Université, Marseille, France [2] INSERM U1104, Marseille, France [3] CNRS UMR7280, Marseille, France.
authors: Emilie
authors: E
authors: Narni-Mancinelli
authors: 1] Centre d'Immunologie de Marseille-Luminy, UM2 Aix-Marseille Université, Marseille, France [2] INSERM U1104, Marseille, France [3] CNRS UMR7280, Marseille, France [4] Service d'Immunologie, Assistance Publique-Hôpitaux de Marseille, Hôpital de la Conception, Marseille, France.
authors: Eric
authors: E
authors: Vivier
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000276:immunology*; D015395:Histocompatibility Antigens Class I / Q000276:immunology*; D007694:Killer Cells, Natural / Q000276:immunology*; D055655:NK Cell Lectin-Like Receptor Subfamily K / Q000276:immunology*; D009369:Neoplasms / Q000276:immunology*
chemical_list: D002352:Carrier Proteins; D015395:Histocompatibility Antigens Class I; D055655:NK Cell Lectin-Like Receptor Subfamily K