title: Lipid trafficking at endoplasmic reticulum-chloroplast membrane contact sites.
abstract: Glycerolipid synthesis in plant cells is characterized by an intense trafficking of lipids between the endoplasmic reticulum (ER) and chloroplasts. Initially, fatty acids are synthesized within chloroplasts and are exported to the ER where they are used to build up phospholipids and triacylglycerol. Ultimately, derivatives of these phospholipids return to chloroplasts to form galactolipids, monogalactosyldiacylglycerol and digalactosyldiacylglycerol, the main and essential lipids of photosynthetic membranes. Lipid trafficking was proposed to transit through membrane contact sites (MCSs) connecting both organelles. Here, we review recent insights into ER-chloroplast MCSs and lipid trafficking between chloroplasts and the ER.
authors: Laboratoire de Physiologie Cellulaire et Végétale, Unité Mixte Recherche 5168, Centre National Recherche Scientifique, Université de Grenoble-Alpes, Institut National de la Recherche Agronomique, Commissariat à l'Energie Atomique et Energies Alternatives, Institut de Recherches en Technologies et Sciences pour le Vivant, 17 Avenue des Martyrs, F-38054 Grenoble, France. Electronic address: Maryse.block@cea.fr.
authors: Maryse A
authors: MA
authors: Block
authors: Laboratoire de Physiologie Cellulaire et Végétale, Unité Mixte Recherche 5168, Centre National Recherche Scientifique, Université de Grenoble-Alpes, Institut National de la Recherche Agronomique, Commissariat à l'Energie Atomique et Energies Alternatives, Institut de Recherches en Technologies et Sciences pour le Vivant, 17 Avenue des Martyrs, F-38054 Grenoble, France.
authors: Juliette
authors: J
authors: Jouhet
mesh_terms: D000818:Animals; D001692:Biological Transport; D002736:Chloroplasts / Q000378:metabolism*; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D050356:Lipid Metabolism; D008055:Lipids
chemical_list: D008055:Lipids