title: Clinical significance of HPV-DNA testing for precancerous cervical lesions.
abstract: Cervical screening by using cytology was proven efficient in reducing the mortality secondary to cervical cancer, but this method has limitations. High risk HPV infection is essential for cervical cancer development so HPV testing is a new tool used for screening patients for cervical neoplasia. HPV testing was proven most useful for women over 30 years old, in cases in which cytology identified ASC-US and after treatment for CIN. This article outlines the clinical significance of HPV-DNA testing for precancerous cervical lesions and the evidence that stands behind these recommendations.
authors: Obstetrics and Gynaecology Department, University Emergency Hospital, Bucharest.
authors: M
authors: M
authors: Moarcăs
authors: Obstetrics and Gynaecology Department, University Emergency Hospital, Bucharest.
authors: I C
authors: IC
authors: Georgescu
authors: Obstetrics and Gynaecology Department, "Sf. Pantelimon" Emergency Hospital.
authors: E
authors: E
authors: Brătilă
authors: Micomi Clinic, Bucharest.
authors: M
authors: M
authors: Badea
authors: Obstetrics and Gynaecology Department, University Emergency Hospital, Bucharest.
authors: M
authors: M
authors: Cîrstoiu
mesh_terms: D000328:Adult; D065309:Atypical Squamous Cells of the Cervix / Q000473:pathology / Q000821:virology; D004279:DNA, Viral / Q000032:analysis* / Q000235:genetics; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000821:virology; D011230:Precancerous Conditions / Q000175:diagnosis* / Q000473:pathology / Q000821:virology*; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000821:virology*; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis / Q000473:pathology / Q000821:virology
chemical_list: D004279:DNA, Viral
keywords: HPV; precancerous cervical lesions; screening