title: Risk factors for superficial incisional surgical site infection after gastrectomy: analysis of patients enrolled in a prospective randomized trial comparing skin closure methods.
abstract: BACKGROUND
  Surgical site infection is one of the commonest complications of gastrointestinal surgery. The nature of surgical procedures and wound closure methods may influence the incidence of superficial incisional surgical site infection. Patients enrolled in a prospective randomized controlled trial comparing skin closure methods are the best subjects for analyzing surgical site infection risk.
  
  
  METHODS
  From a cohort of 1080 patients who had been enrolled in our previous randomized controlled trial, data for 685 patients who had undergone elective open total gastrectomy or distal gastrectomy for gastric cancer were extracted. The incidences of superficial incisional surgical site infection after total gastrectomy and distal gastrectomy were compared and risk factors for superficial incisional surgical site infection were investigated by univariate analyses using logistic regression models.
  
  
  RESULTS
  In all, 42 patients (6.1 %) developed superficial incisional surgical site infections after gastrectomy; 15 of 288 patients (5.2 %) developed these infections after total gastrectomy, and 27 of 397 patients (6.8 %) developed these infections after distal gastrectomy-these differences are not significant. According to univariate analysis, age (75 years or older or younger than 75 years) was the only risk factor for superficial incisional surgical site infections (P = 0.049). There was a tendency for the incidence of superficial incisional surgical site infection to increase in parallel with age.
  
  
  CONCLUSIONS
  The incidence of superficial incisional surgical site infection did not differ between total gastrectomy and distal gastrectomy. Advanced age was the only identified risk factor for superficial incisional surgical site infections after gastrectomy.
authors: Department of Gastroenterological Surgery, Higashiosaka City General Hospital, Osaka, Japan. endo-s@higashiosaka-hosp.jp.
authors: Shunji
authors: S
authors: Endo
authors: Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.|Department of Surgery, Kaizuka City Hospital, Osaka, Japan.
authors: Toshimasa
authors: T
authors: Tsujinaka
authors: Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.|Department of Surgery, Osaka General Medical Center, Osaka, Japan.
authors: Kazumasa
authors: K
authors: Fujitani
authors: Department of Gastroenterological Surgery, Toyonaka Municipal Hospital, Osaka, Japan.|Department of Surgery, NTT WEST Osaka Hospital, Osaka, Japan.
authors: Junya
authors: J
authors: Fujita
authors: Department of Surgery, Kansai Rosai Hospital, Hyogo, Japan.
authors: Shigeyuki
authors: S
authors: Tamura
authors: Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors: Makoto
authors: M
authors: Yamasaki
authors: Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.|Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
authors: Shogo
authors: S
authors: Kobayashi
authors: Department of Surgery, Japan Community Health Care Organization Osaka Hospital, Osaka, Japan.
authors: Yusuke
authors: Y
authors: Akamaru
authors: Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors: Tsunekazu
authors: T
authors: Mizushima
authors: Department of Surgery, Osaka Rosai Hospital, Osaka, Japan.
authors: Junzo
authors: J
authors: Shimizu
authors: Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors: Koji
authors: K
authors: Umeshita
authors: Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors: Toshinori
authors: T
authors: Ito
authors: Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors: Masaki
authors: M
authors: Mori
authors: Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors: Yuichiro
authors: Y
authors: Doki
mesh_terms: D000367:Age Factors; D000368:Aged; D015992:Body Mass Index; D005260:Female; D005743:Gastrectomy / Q000009:adverse effects* / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000601:surgery*; D013530:Surgical Wound Infection / Q000453:epidemiology / Q000209:etiology*; D058106:Wound Closure Techniques
keywords: Gastrectomy; Stomach neoplasms; Surgical wound infection