title: The value of myocardial torsion and aneurysm volume for evaluating cardiac function in rabbit with left ventricular aneurysm.
abstract: OBJECTIVE
  This study aimed to investigate the effect of left ventricular aneurysm (LVA) volume and left ventricular global torsion on cardiac function by real time three-dimensional echocardiography (RT-3DE) and two-dimensional speckle tracking imaging(2D-STI), to determine the accuracy of RT-3DE and 2D-STI in assessing LV function.
  
  
  METHODS
  Thirty New Zealand rabbit models of with LVA were prepared by ligation of the middle segment of the left anterior descending and left circumflex arteries. Four weeks post-procedure, RT-3DE was conducted to obtain data on LVEF, left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), and LVA volume (LVAV), Peak rotation angles at the mitral valve annulus level (MV-ROT), peak rotation angles at the apical level (AP-ROT), and left ventricular global torsion angles (LV-TOR) were measured by 2D-STI.
  
  
  RESULTS
  Compared with controls, LVEDV and LVESV were significantly increased in the LVA group, while LVEF, MV-ROT, AP-ROT, and LV-TOR were consistently reduced (p<0.01). Moreover, LVEF correlated with LVA volume and LV torsion angle (r= -0.778 and 0.821, p<0.01). LVA volume/LVEDV had the strongest inverse relationship with LVEF (r= -0.911, p<0.01).
  
  
  CONCLUSIONS
  LVA volume, LVA volume/LVEDV, and LV torsion may be used as an indicator for evaluation of cardiac function after LVA. Moreover, LVA volume/LVEDV may be a more sensitive and reliable marker of cardiac function after LVA formation.
authors: Department of Ultrasonography, Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China.
authors: Zhai
authors: Z
authors: Hong
authors: Department of Echocardiography, First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China.
authors: Mu
authors: M
authors: Yuming
authors: Department of Echocardiography, First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China.
authors: Wang
authors: W
authors: Chunmei
authors: Department of Echocardiography, First Affiliated Hospital, Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, China.
authors: Yan
authors: Y
authors: Xue
mesh_terms: D000818:Animals; D004452:Echocardiography / Q000379:methods; D019560:Echocardiography, Three-Dimensional / Q000379:methods; D006321:Heart / Q000502:physiology*; D006322:Heart Aneurysm / Q000473:pathology*; D006334:Heart Function Tests; D006352:Heart Ventricles / Q000473:pathology*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D016014:Linear Models; D064847:Multimodal Imaging / Q000379:methods*; D011817:Rabbits; D014102:Torsion Abnormality / Q000473:pathology*