title: Sensitization to workplace respiratory allergens among bakery workers in Douala, Cameroon: a cross-sectional study.
abstract: BACKGROUND
  Sensitization to flour or fungal alpha-amylase is a prerequisite for the development of respiratory allergy in bakers. The knowledge of occupational allergen sensitization among bakery workers will facilitate the implementation of preventive measures for respiratory allergies in bakeries. The objective of this study was to determine the prevalence and factors associated with sensitization to wheat flour and α-amylase in bakers in Douala.
  
  
  METHODS
  A cross-sectional study was conducted in 42 of the 151 bakeries that are present in the city of Douala. Demographics, clinical data, as well as results of skin prick tests to wheat flour, α-amylase and common aeroallergens were collected from all participants. A logistic regression model of the SPSS.20 software was used to identify factors associated with sensitization to wheat flour and α-amylase.
  
  
  RESULTS
  Of the 229 participants included in the study, 222 (96.9%) were male. The mean age was 36.3 ± 8.9 years. The prevalence of sensitization to flour and α-amylase were 16.6% and 8.3% respectively. After multivariate analysis, factors associated with sensitization to flour were work seniority and sensitization to storage mites while an age of 30 years and above was the only factor associated with sensitization to α-amylase.
  
  
  CONCLUSIONS
  Bakers in Douala are at risk of sensitization to occupational allergens. The environmental hygiene in bakeries, health surveillance and the use of personal protective equipment could reduce the risk of respiratory allergies among bakers.
authors: Internal Medicine, Douala General Hospital, PO Box 4856, Douala, Cameroon ; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon ; Douala Research Network, Douala, Cameroon.
authors: Bertrand Hugo
authors: BH
authors: Mbatchou Ngahane
authors: Ecole de Santé Publique, Université Libre de Bruxelles, Bruxelles, Belgium.
authors: Francis
authors: F
authors: Nde
authors: Université des Montagnes, Bangangte, Cameroon.
authors: Eliane
authors: E
authors: Ngomo
authors: Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon.
authors: Emmanuel
authors: E
authors: Afane Ze
keywords: Allergen sensitization; Asthma; Bakeries; Wheat allergen; α-amylase