title: [Assessment of risk factors for patients with anatomical left ventricular aneurysm post acute ST-elevation myocardial infarction by use of multiple-risk-factor assessment models].
abstract: OBJECTIVE
  To set up the multiple risk factors model of patients with anatomical left ventricular aneurysm (LVA) post acute ST-elevation myocardial infarction (STEMI) and quantitatively assess the pathopoiesis of all the factors.
  
  
  METHODS
  A total of 518 consecutive inpatients with acute STEMI hospitalized from June 2010 to December 2013 in our hospital were enrolled in this study, patients were divided into two groups: LVA group (n = 106, 20.5%) and non-LVA group (n = 412, 79.5%). All demographic and clinical data were collected by cardiologists. Finally, all of the risk factors for anatomical LVA in the acute STEMI patients were quantitatively analyzed by a binary logistic regression model.
  
  
  RESULTS
  The multiple risk factors logistic regression model was set up for the anatomical LVA in patients with acute STEMI. Anterior wall myocardial infarction, occlusion of the left anterior descending branch, two or three vessels stenosis, high systolic blood pressure, sinus tachycardia and white blood cell count over 10 000 per microliter were all independent risk factors of the LVA in acute STEMI, with the odds ratio (OR) 18.21, 21.56, 4.22, 7.16, 1.98 and 1.57, respectively (all P < 0.05) . However, first medical contact less than 12 hours (OR = 0.60), collateral circulation of the coronary arteries(OR = 0.53), primary percutanous coronary intervention(OR = 0.23) and venous thrombolysis(OR = 0.12) were all protecting factors of the LVA in acute STEMI patients (all P < 0.05).
  
  
  CONCLUSIONS
  Anterior wall STEMI, occlusion of the left anterior descending branch, two or three vessels stenosis, high systolic blood pressure, sinus tachycardia and white blood cell count over 10 000 per microlitre are independent risk factors of the LVA in acute STEMI patients. However, first medical contact less than twelve hours, collateral circulation of the coronary arteries, together with the primary percutanous coronary intervention and venous thrombolysis are protective factors of the LVA in patients with acute STEMI. It is important for cardiologists to assess the risks of LVA and make emergent and suitable efforts to reduce the risk of developing LVA in STEMI patients.
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.
authors: Wanglexian
authors: W
authors: Sun
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.
authors: Huiling
authors: H
authors: Liu
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.
authors: Na
authors: N
authors: Zhang
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.
authors: Aiwen
authors: A
authors: Zhang
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.
authors: Mingfei
authors: M
authors: Ju
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.
authors: Wenfeng
authors: W
authors: Wang
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.
authors: Fei
authors: F
authors: Shi
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.
authors: Na
authors: N
authors: Hu
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.
authors: Jing
authors: J
authors: Sun
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.
authors: Haiwei
authors: H
authors: Bu
authors: Division of Cardiovascular Medicine, Institute of Cardiovascular Medicine, Affiliated Hospital of Chengde Medical College, Chengde Medical College, Chengde 067000, China.Email: lichunhua9522@163.com.
authors: Chunhua
authors: C
authors: Li
mesh_terms: D000208:Acute Disease; D056988:Anterior Wall Myocardial Infarction; D003097:Collateral Circulation; D006322:Heart Aneurysm / Q000453:epidemiology*; D006801:Humans; D016015:Logistic Models; D009203:Myocardial Infarction; D012307:Risk Factors