title: Does melissa officinalis cause withdrawal or dependence?
abstract: BACKGROUND
  Melissa officinalis is a medical and aromatic plant that is used for its hypnotic, sedative, and spasmolytic effects. This report presents a case study of30-year-old patient who was admitted to an emergency department with restlessness, tremor, distractibility, and sweating following a discontinuation of Melissa officinalis consumption.
  
  
  METHODS
  In this case, withdrawal symptoms may be related to the dependence effect caused by long-term use of Melissa officinalis. Although Melissa officinalis, a plant, is preferred by many patients as an alternative to pharmaceutical drugs, patients should be made aware that it may have a risk of dependency and can lead to withdrawal symptoms.
authors: Department of Psychiatry, School of Medicine, Süleyman Demirel University, Isparta, Turkey.
authors: Kadir
authors: K
authors: Demirci
authors: Department of Psychiatry, School of Medicine, Süleyman Demirel University, Isparta, Turkey.
authors: Mehmet
authors: M
authors: Akgönül
authors: Department of Psychiatry, School of Medicine, Süleyman Demirel University, Isparta, Turkey.
authors: Arif
authors: A
authors: Demirdaş
authors: Department of Psychiatry, School of Medicine, Süleyman Demirel University, Isparta, Turkey.
authors: Abdullah
authors: A
authors: Akpınar
mesh_terms: D000328:Adult; D002998:Clonazepam / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D031334:Melissa / Q000009:adverse effects*; D010946:Plants, Medicinal / Q000009:adverse effects*; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy* / Q000209:etiology*; D019966:Substance-Related Disorders / Q000150:complications*; D016896:Treatment Outcome
chemical_list: D002998:Clonazepam
keywords: Melissa officinalis; dependence; withdrawal