title: Prevalence of diabetes mellitus and prediabetes in the adult Romanian population: PREDATORR study.
abstract: BACKGROUND
  The PREDATORR (PREvalence of DiAbeTes mellitus, prediabetes, overweight, Obesity, dyslipidemia, hyperuricemia and chronic kidney disease in Romania) study is the first national study analyzing the prevalence of diabetes mellitus (DM) and prediabetes, and their association with cardiometabolic, sociodemographic, and lifestyle risk factors in the Romanian population aged 20-79 years.
  
  
  METHODS
  This was an epidemiological study with a stratified, cross-sectional, cluster random sampling design. Sociodemographic, lifestyle, and anamnestic data were collected through self- and interviewer-administered questionnaires, and biochemical assays and oral glucose tolerance tests were performed.
  
  
  RESULTS
  In all, 2728 participants from 101 clinics of general practitioners were randomly selected, with a probability proportional to population size according to the 2002 Romanian Census. The participation rate was 99.6%. Impaired glucose regulation (prediabetes, known and unknown DM) was found in 28.1% of the study population. The overall age- and sex-adjusted prevalence of DM was 11.6% (95% CI 9.6%-13.6%), of which 2.4% (95% CI 1.7%-3.1%) had unknown DM. The prevalence of DM increased with age and was higher in men than in women. The age- and sex-adjusted prevalence of prediabetes was 16.5% (95%CI 14.8%-18.2%), with the highest percentage in the 60-79 year age group and in women. Obesity, abdominal obesity, dyslipidemia, low education level, and a family history of diabetes were associated with glucose metabolism disorders.
  
  
  CONCLUSIONS
  The PREDATORR study shows a high prevalence of impaired glucose regulation in the adult Romanian population, providing data on the prevalence of DM and prediabetes and their association with several risk factors.
authors: Department of Diabetes, Nutrition and Metabolic Diseases, University of Medicine and Pharmacy, Craiova, Romania.
authors: Maria
authors: M
authors: Mota
authors: Department of Diabetes, Nutrition and Metabolic Diseases, University of Medicine and Pharmacy, Craiova, Romania.
authors: Simona Georgiana
authors: SG
authors: Popa
authors: Department of Nephrology, University of Medicine and Pharmacy, Craiova, Romania.
authors: Eugen
authors: E
authors: Mota
authors: Department of Diabetes, Nutrition and Metabolic Diseases, Clinical Emergency Hospital, Craiova, Romania.
authors: Adina
authors: A
authors: Mitrea
authors: Faculty of Medicine, "Ovidius" University, Constanţa, Romania.
authors: Doina
authors: D
authors: Catrinoiu
authors: Nutrition and Metabolic Diseases, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
authors: Dan Mircea
authors: DM
authors: Cheta
authors: Nutrition and Metabolic Diseases, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
authors: Cristian
authors: C
authors: Guja
authors: Diabetes and Nutrition Diseases, University of Medicine and Pharmacy "Iuliu Hatieganu", Cluj-Napoca, Romania.
authors: Nicolae
authors: N
authors: Hancu
authors: Nutrition and Metabolic Diseases, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
authors: Constantin
authors: C
authors: Ionescu-Tirgoviste
authors: Nutrition and Metabolic Diseases, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
authors: Radu
authors: R
authors: Lichiardopol
authors: Diabetes, Nutrition and Metabolic Diseases, University of Medicine and Pharmacy "Gr. T. Popa", Iaşi, Romania.
authors: Bogdan Mircea
authors: BM
authors: Mihai
authors: Faculty of Medicine, University of Oradea, Oradea, Romania.
authors: Amorin Remus
authors: AR
authors: Popa
authors: Nutrition and Metabolic Diseases, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
authors: Cornelia
authors: C
authors: Zetu
authors: Diabetes and Nutrition Diseases, University of Medicine and Pharmacy "Iuliu Hatieganu", Cluj-Napoca, Romania.
authors: Cornelia Gabriela
authors: CG
authors: Bala
authors: Diabetes and Nutrition Diseases, University of Medicine and Pharmacy "Iuliu Hatieganu", Cluj-Napoca, Romania.
authors: Gabriela
authors: G
authors: Roman
authors: Nutrition and Metabolic Diseases, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
authors: Cristian
authors: C
authors: Serafinceanu
authors: Diabetes, Nutrition and Metabolic Diseases, University of Medicine and Pharmacy "Victor Babeş", Timişoara, Romania.
authors: Viorel
authors: V
authors: Serban
authors: Diabetes, Nutrition and Metabolic Diseases, University of Medicine and Pharmacy "Victor Babeş", Timişoara, Romania.
authors: Romulus
authors: R
authors: Timar
authors: Diabetes and Nutrition Diseases, University of Medicine and Pharmacy "Iuliu Hatieganu", Cluj-Napoca, Romania.
authors: Ioan Andrei
authors: IA
authors: Veresiu
authors: Diabetes, Nutrition and Metabolic Diseases, University of Medicine and Pharmacy "Victor Babeş", Timişoara, Romania.
authors: Adrian Radu
authors: AR
authors: Vlad
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005260:Female; D018149:Glucose Intolerance / Q000150:complications*; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology*; D011236:Prediabetic State / Q000453:epidemiology*; D015995:Prevalence; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D012307:Risk Factors; D012383:Romania; D055815:Young Adult
keywords: Romania; diabetes mellitus; epidemiology; prediabetes; 流行病学; 糖尿病; 糖尿病前期; 罗马尼亚