title: Effects of six months of Yoga on inflammatory serum markers prognostic of recurrence risk in breast cancer survivors.
abstract: Yoga-based exercise has proven to be beneficial for practitioners, including cancer survivors. This study reports on the effect on inflammatory biological markers for 20 breast cancer survivors who participated in a six-month yoga-based (YE) exercise program. Results are compared to a comprehensive exercise (CE) program group and a comparison (C) exercise group who chose their own exercises. "Pre" and "post" assessments included measures of anthropometrics, cardiorespiratory capacity, and inflammatory markers interleukin 6 (IL-6), interleukin 8 (IL-8), tumor necrosis factor alpha (TNFα) and C-reactive protein (CRP). Descriptive statistics, effect size (d), and dependent sample 't' tests for all outcome measures were calculated for the YE group. Significant improvements were seen in decreased % body fat, (-3.00%, d = -0.44, p = <.001) but not in cardiorespiratory capacity or in inflammatory serum markers. To compare YE outcomes with the other two groups, a one-way analysis of co-variance (ANCOVA) was used, controlling for age, BMI, cardiorespiratory capacity and serum marker baseline values. We found no differences between groups. Moreover, we did not see significant changes in any inflammatory marker for any group. Our results support the effectiveness of yoga-based exercise modified for breast cancer survivors for improving body composition. Larger studies are needed to determine if there are significant changes in inflammatory serum markers as a result of specific exercise modalities.
authors: Department of Epidemiology and Biostatistics, Institute for Health Promotion Research, University of Texas Health Science Center at San Antonio, 7411 John Smith Drive Suite 1000, San Antonio, TX USA.
authors: Dorothy
authors: D
authors: Long Parma
authors: Department of Epidemiology and Biostatistics, Institute for Health Promotion Research, University of Texas Health Science Center at San Antonio, 7411 John Smith Drive Suite 1000, San Antonio, TX USA.
authors: Daniel C
authors: DC
authors: Hughes
authors: SRA International, Inc., Fairfax, VA USA.
authors: Sagar
authors: S
authors: Ghosh
authors: Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, TX USA.
authors: Rong
authors: R
authors: Li
authors: Department of Epidemiology and Biostatistics, Institute for Health Promotion Research, University of Texas Health Science Center at San Antonio, 7411 John Smith Drive Suite 1000, San Antonio, TX USA.
authors: Rose A
authors: RA
authors: Treviño-Whitaker
authors: Department of Epidemiology and Biostatistics, Institute for Health Promotion Research, University of Texas Health Science Center at San Antonio, 7411 John Smith Drive Suite 1000, San Antonio, TX USA.
authors: Susan M
authors: SM
authors: Ogden
authors: Department of Epidemiology and Biostatistics, Institute for Health Promotion Research, University of Texas Health Science Center at San Antonio, 7411 John Smith Drive Suite 1000, San Antonio, TX USA.
authors: Amelie G
authors: AG
authors: Ramirez
keywords: Biomarker; Breast cancer survivors; Exercise; Inflammation; Yoga