title: Chronic candida endophthalmitis as a cause of intermediate uveitis.
abstract: Intermediate uveitis is a subset of intraocular inflammation where vitritis is the most consistent sign, with or without snowball opacities or snow banks over the pars plana. Some patients will have an associated underlying systemic disease such as sarcoidosis, multiple sclerosis, ocular tuberculosis, inflammatory bowel disease, possibly Behçet's disease and intraocular lymphoma, whereas some will be classified as pars planitis in case of the lack of an identifiable systemic disease association. Our patient, a 47-year-old woman, developed intermediate uveitis after cataract surgery in her right eye, was misdiagnosed as pars planitis, and received steroid monotherapy for 8 months. Her inflammation only fully resolved after vitrectomy with removal of the intraocular lens (IOL) and capsular bag. Oral fluconazole and intravitreal amphotericin B injection had failed to resolve her inflammation when Candida albicans was identified as the cause of her persistent intermediate uveitis.
authors: Department of Ophthalmology, Alexandria Faculty of Medicine, Alexandria, Egypt.
authors: Rowayda Mohamed
authors: RM
authors: Amin
authors: Department of Vitreoretinal Diseases, Alexandria Faculty of Medicine, Alexandria, Egypt.
authors: Islam
authors: I
authors: Hamdy
authors: Alexandria Faculty of Medicine, Alexandria, Egypt.
authors: Ihab Mohamed
authors: IM
authors: Osman
mesh_terms: D000284:Administration, Oral; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use; D002176:Candida albicans / Q000302:isolation & purification*; D002387:Cataract Extraction / Q000379:methods; D003951:Diagnostic Errors; D009877:Endophthalmitis / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology; D015821:Eye Infections, Fungal / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D015725:Fluconazole / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D058449:Intravitreal Injections; D008875:Middle Aged; D015868:Pars Planitis / Q000175:diagnosis; D011183:Postoperative Complications / Q000175:diagnosis; D013256:Steroids / Q000008:administration & dosage / Q000627:therapeutic use; D016896:Treatment Outcome; D015867:Uveitis, Intermediate / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D014821:Vitrectomy / Q000379:methods
chemical_list: D013256:Steroids; D000666:Amphotericin B; D015725:Fluconazole