title: Effects of 92% oxygen administration on cognitive performance and physiological changes of intellectually and developmentally disabled people.
abstract: BACKGROUND
  The present study addressed how 92% oxygen administration affects cognitive performance, blood oxygen saturation (SpO2), and heart rate (HR) of intellectually and developmentally disabled people.
  
  
  METHODS
  Seven males (28.9 ± 1.8 years) and seven females (34.4 ± 8.3 years) with intellectual and developmental disabilities (disabled level 2.1 ± 0.5) completed an experiment consisting a 0-back task with normal air (21% oxygen) administered in one run and hyperoxic air (92% oxygen) administered in the other run. The experimental sequence in each run consisted of a 1-min adaptation phase, 2-min control phase, and 2-min 0-back task phase, where SpO2 and HR were gauged for each phase.
  
  
  RESULTS
  The administration of 92% oxygen increased 0-back task performance of intellectually and developmentally disabled people, in association with increased SpO2 and decreased HR. Our results demonstrate that sufficient oxygen supply subserving cognitive functions, even as a short-term effect, could increase cognitive ability for the intellectually and developmentally disabled people.
  
  
  CONCLUSIONS
  It is concluded that enriched oxygen can positively affect, at least in the short-term, the working memory of those with intellectual and developmental disability.
authors: Hyung-Sik
authors: HS
authors: Kim
authors: Mi-Hyun
authors: MH
authors: Choi
authors: Ji-Hye
authors: JH
authors: Baek
authors: Sung-Jun
authors: SJ
authors: Park
authors: Jung-Chul
authors: JC
authors: Lee
authors: Ul-Ho
authors: UH
authors: Jeong
authors: Sung-Phil
authors: SP
authors: Kim
authors: Hyun-Jun
authors: HJ
authors: Kim
authors: Young
authors: Y
authors: Choi
authors: Dae-Woon
authors: DW
authors: Lim
authors: Soon-Cheol
authors: SC
authors: Chung
mesh_terms: D000328:Adult; D001288:Attention / Q000187:drug effects; D003071:Cognition / Q000187:drug effects*; D002658:Developmental Disabilities / Q000503:physiopathology*; D005260:Female; D006339:Heart Rate; D006801:Humans; D008607:Intellectual Disability / Q000503:physiopathology*; D008297:Male; D010100:Oxygen / Q000008:administration & dosage* / Q000097:blood / Q000494:pharmacology*
chemical_list: D010100:Oxygen