title: Synthesis, characterization, and application of microbe-triggered controlled-release kasugamycin-pectin conjugate.
abstract: The controlled and targeted release of pesticides with high water solubility has been a challenge for integrated pest management. In this paper, kasugamycin, an antibiotic broadly used in plant disease control, was covalently conjugated to pectin to form a kasugamycin-pectin conjugate by an amide bond. The conjugate was structurally characterized by Fourier transform infrared spectroscopy, ultraviolet spectrophotometry, and thermal gravimetric analysis. The results showed that the conjugate was stable over a wide range of pH and temperatures, as well as under UV irradiation. When incubated with Pseudomonas syringae pv. lachrymans, the conjugate could be activated, releasing the kasugamycin, which made it a promising controlled-release formulation of pesticide.
authors: College of Agriculture and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Beijing, China.
authors: Yao
authors: Y
authors: Liu
authors: College of Agriculture and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Beijing, China.
authors: Yan
authors: Y
authors: Sun
authors: College of Agriculture and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Beijing, China.
authors: Guanglong
authors: G
authors: Ding
authors: College of Agriculture and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Beijing, China.
authors: Qianqian
authors: Q
authors: Geng
authors: College of Agriculture and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Beijing, China.
authors: Juanli
authors: J
authors: Zhu
authors: College of Agriculture and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Beijing, China.
authors: Mingcheng
authors: M
authors: Guo
authors: College of Agriculture and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Beijing, China.
authors: Yongheng
authors: Y
authors: Duan
authors: College of Agriculture and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Beijing, China.
authors: Baitao
authors: B
authors: Wang
authors: College of Agriculture and Biotechnology, China Agricultural University, 2 Yuanmingyuan West Road, Beijing, China.
authors: Yongsong
authors: Y
authors: Cao
mesh_terms: D000617:Aminoglycosides / Q000737:chemistry / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D003692:Delayed-Action Preparations / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D004337:Drug Carriers / Q000737:chemistry; D016503:Drug Delivery Systems; D010368:Pectins / Q000737:chemistry; D010575:Pesticides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D010935:Plant Diseases / Q000382:microbiology / Q000517:prevention & control; D044224:Pseudomonas syringae / Q000187:drug effects* / Q000502:physiology
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D010575:Pesticides; D010368:Pectins; C100305:kasugamycin
keywords: controlled release; kasugamycin; microbe-triggered; pectin