title: Superior parietal lobule approach for choroid plexus papillomas without preoperative embolization in very young children.
abstract: OBJECT Choroid plexus papillomas (CPPs) are rare neoplasms, often found in the atrium of the lateral ventricle of infants, and cause overproduction hydrocephalus. The extensive vascularity and medially located blood supply of these tumors, coupled with the young age of the patients, can make prevention of blood loss challenging. Preoperative embolization has been advocated to reduce blood loss and prevent the need for transfusion, but this mandates radiation exposure and the additional risks of vessel injury and stroke. For these reasons, the authors present their experience using the superior parietal lobule approach to CPPs of the atrium without adjunct therapy. METHODS A retrospective review was conducted of all children who presented to Columbia University/Morgan Stanley Children's Hospital of New York with a CPP in the atrium of the lateral ventricle and who underwent surgery using a superior parietal lobule approach without preoperative embolization. RESULTS Nine children were included, with a median age of 7 months. There were no perioperative complications or new neurological deficits. All patients had intraoperative blood loss of less than 100 ml, with a mean minimum hematocrit of 26.9% (range 19.6%-36.2%). No patients required a blood transfusion. The median follow-up was 39 months, during which time no patient demonstrated residual or recurrent tumor on MRI, nor did any have an increase in ventricular size or require CSF diversion. CONCLUSIONS The superior parietal lobule approach is safe and effective for very young children with CPPs in the atrium of the lateral ventricle. The results suggest that preoperative embolization is not essential to avoid transfusion or achieve overall good outcomes in these patients. This management strategy avoids radiation exposure and the additional risks associated with embolization.
authors: Department of Neurological Surgery and.
authors: Benjamin C
authors: BC
authors: Kennedy
authors: Department of Neurological Surgery and.
authors: Michael B
authors: MB
authors: Cloney
authors: Department of Neurological Surgery and.|Children's Hospital of New York, Columbia University, New York, New York.
authors: Richard C E
authors: RC
authors: Anderson
authors: Department of Neurological Surgery and.|Children's Hospital of New York, Columbia University, New York, New York.
authors: Neil A
authors: NA
authors: Feldstein
mesh_terms: D016063:Blood Loss, Surgical / Q000706:statistics & numerical data; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006785:Hospitals, University; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007223:Infant; D020547:Lateral Ventricles / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures / Q000009:adverse effects / Q000379:methods*; D009519:New York City; D010212:Papilloma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D020288:Papilloma, Choroid Plexus / Q000150:complications / Q000473:pathology / Q000601:surgery*; D010296:Parietal Lobe / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D018401:Sample Size; D016896:Treatment Outcome
keywords: CPP = choroid plexus papilloma; children; choroid plexus papilloma; embolization; pediatrics; superior parietal lobule approach; technique