title: Modelling catheter-vein biomechanical interactions during an intravenous procedure.
abstract: A reliable intravenous (IV) access into the upper extremity veins requires the insertion of a temporary short peripheral catheter (SPC). This so common procedure is, however, associated with a risk of developing short peripheral catheter thrombophlebitis (SPCT) which causes distress and potentially prolongs patient hospitalization. We have developed and studied a biomechanical SPC-vein computational model during an IV procedure, and explored the biomechanical effects of repeated IV episodes on onset and reoccurrences of SPCT. The model was used to determine the effects of different insertion techniques as well as inter-patient biological variability on the catheter-vein wall contact pressures and wall deformations. We found that the maximal pressure exerted upon the vein wall was inhomogeneously distributed, and that the bending region was exposed to significantly greater pressures and deformations. The maximal exerted contact pressure on the inner vein's wall was 2938 Pa. The maximal extent of the SPC penetration into the vein wall reached 3.6 μm, which corresponds to approximately 100% of the average height of the inner layer, suggesting local squashing of endothelial cells at the contact site. The modelling describes a potential biomechanical damage pathway that can explain the reoccurrence of SPCT.
authors: a Department of Biomedical Engineering , Faculty of Engineering, Tel Aviv University , Tel Aviv 69978 , Israel.
authors: Dar
authors: D
authors: Weiss
authors: a Department of Biomedical Engineering , Faculty of Engineering, Tel Aviv University , Tel Aviv 69978 , Israel.
authors: Amit
authors: A
authors: Gefen
authors: a Department of Biomedical Engineering , Faculty of Engineering, Tel Aviv University , Tel Aviv 69978 , Israel.|b Stony Brook University , Stony Brook , NY , USA.
authors: Shmuel
authors: S
authors: Einav
mesh_terms: D000328:Adult; D001132:Arm / Q000098:blood supply*; D001696:Biomechanical Phenomena; D002406:Catheterization, Peripheral; D003198:Computer Simulation; D020342:Finite Element Analysis; D006801:Humans; D008954:Models, Biological; D011187:Posture; D012680:Sensitivity and Specificity; D014680:Veins / Q000502:physiology*
keywords: finite element modelling; pressure; short peripheral catheter; thrombophlebitis