title: Protein-quantum dot nanohybrids for bioanalytical applications.
abstract: Quantum dots (QDs) coupled with biomolecules play an important role as optically and chemically stable bioimaging agents for various applications. These inorganic-biological hybrid conjugates have been demonstrated as powerful fluorescence tools for sensing, diagnostics, and labeling. This review focuses on protein-QD nanohybrids for different types of bioanalytical applications. There are various strategies to modify the surface properties of QDs to produce protein-QD nanohybrids that are stable in biological fluids. We expect that multifunctional protein-QD nanohybrids can be used as a powerful optical probe for various biological applications. WIREs Nanomed Nanobiotechnol 2016, 8:178-190. doi: 10.1002/wnan.1345 For further resources related to this article, please visit the WIREs website.
authors: Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
authors: Jeong Yu
authors: JY
authors: Lee
authors: Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
authors: Jee Seon
authors: JS
authors: Kim
authors: Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
authors: Jae Chul
authors: JC
authors: Park
authors: Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.|KAIST Institute for NanoCentury (KINC CNiT), Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
authors: Yoon Sung
authors: YS
authors: Nam
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D015374:Biosensing Techniques / Q000379:methods*; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D055620:Optical Phenomena; D011506:Proteins / Q000378:metabolism*; D045663:Quantum Dots / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D011506:Proteins