title: An innovative arrangement for in-vial membrane-assisted liquid-liquid microextraction: application to the determination of esters of phthalic acid in alcoholic beverages by gas chromatography-mass spectrometry.
abstract: A new arrangement for membrane-assisted liquid-liquid microextraction is presented. The extracting organic solvent was placed into a chromatographic microvial, compatible with the chromatograph autosampler, whose septum was replaced by a disc of porous hydrophobic membrane. This extraction device was completely immersed into the analytical sample contained in a cylindrical container subjected to rotary and basculant movement. Then, the extraction of analytes took place from the sample to the organic solvent contained in the vial through the membrane. Esters of the phthalic acid have been selected as model analytes to determine the performance characteristics of the extraction system. The limits of detection, limits of quantification and relative standard deviations (%) were in the range 0.1-0.4, 0.3-1 and 4-7, respectively. Esters of phthalic acid have been successfully analysed in alcoholic beverages. The main operational advantages of this arrangement consisted of minimal required handling, minimal risk of cross contamination and its simplicity.
authors: Department of Chemistry, University of Balearic Islands, Carretera de Valldemossa, Km 7,5, 07122, Palma de Mallorca, Spain, joan.march@uib.es.
authors: Juan Gabriel
authors: JG
authors: March
authors: Victor
authors: V
authors: Cerdà