title: Cost analysis of tests for the detection of Schistosoma mansoni infection in children in western Kenya.
abstract: Financial resources tend to be limited in schistosomiasis endemic areas, forcing program managers to balance financial and scientific considerations when selecting detection assays. Therefore, we compared the costs of using single stool Kato-Katz, triplicate stool Kato-Katz, and point-of-contact circulating cathodic antigen (POC-CCA) assays for the detection of Schistosoma mansoni infection. Economic and financial costs were estimated from the viewpoint of a schistosomiasis control program using the ingredients approach. Costs related to specimen collection, sample processing and analysis, and treatment delivery were considered. Analysis inputs and assumptions were tested using one-way and two-way sensitivity analysis. The total per-person cost of performing the single Kato-Katz, triplicate Kato-Katz, and POC-CCA was US$6.89, US$17.54, and US$7.26, respectively. Major cost drivers included labor, transportation, and supplies. In addition, we provide a costing tool to guide program managers in evaluating detection costs in specific settings, as costs may vary temporally and spatially.
authors: Parasitic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; Data Management Activity, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
authors: Caitlin M
authors: CM
authors: Worrell
authors: Parasitic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; Data Management Activity, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
authors: Monina
authors: M
authors: Bartoces
authors: Parasitic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; Data Management Activity, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
authors: Diana M S
authors: DM
authors: Karanja
authors: Parasitic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; Data Management Activity, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
authors: Elizabeth A
authors: EA
authors: Ochola
authors: Parasitic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; Data Management Activity, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
authors: Daniel O
authors: DO
authors: Matete
authors: Parasitic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; Data Management Activity, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
authors: Pauline N M
authors: PN
authors: Mwinzi
authors: Parasitic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; Data Management Activity, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
authors: Susan P
authors: SP
authors: Montgomery
authors: Parasitic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; Data Management Activity, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia; Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya was4@cdc.gov.
authors: W Evan
authors: WE
authors: Secor
mesh_terms: D000953:Antigens, Protozoan / Q000652:urine; D002648:Child; D005243:Feces / Q000469:parasitology; D017048:Health Care Costs / Q000706:statistics & numerical data; D006801:Humans; D007630:Kenya / Q000453:epidemiology; D011933:Reagent Kits, Diagnostic / Q000191:economics* / Q000469:parasitology; D012555:Schistosomiasis mansoni / Q000175:diagnosis / Q000191:economics* / Q000453:epidemiology / Q000652:urine; D012574:Schools / Q000191:economics / Q000706:statistics & numerical data; D012680:Sensitivity and Specificity
chemical_list: D000953:Antigens, Protozoan; D011933:Reagent Kits, Diagnostic