title: Frequency of the toxic shock syndrome toxin-1 gene in methicillin-susceptible and -resistant Staphylococcus aureus isolates from teaching hospitals in Shiraz, Iran.
abstract: BACKGROUND
  Staphylococcus aureus produces a range of virulence factors such as toxic shock syndrome toxin-1.
  
  
  METHODS
  In this cross-sectional study of 345 clinical S. aureus isolates, the presence of the tst gene was assessed by polymerase chain reaction (PCR).
  
  
  RESULTS
  The study revealed 53/345 (15.4%) isolates were positive for the tst gene. The tst gene was present in 18.1% of methicillin-susceptible S. aureus (MSSA) isolates and 11.6% of methicillin-resistant S. aureus (MRSA) isolates (p = 0.136).
  
  
  CONCLUSIONS
  These results reveal the remarkable risk of S. aureus infections in hospitals, regardless of methicillin-resistance status.
authors: Department of Bacteriology & Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Mohammad
authors: M
authors: Motamedifar
authors: Department of Bacteriology & Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Hadi Sedigh
authors: HS
authors: Ebrahim-Saraie
authors: Department of Bacteriology & Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Seyedeh Mahsan Hoseini
authors: SM
authors: Alfatemi
authors: Department of Bacteriology & Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Mehrdad
authors: M
authors: Zalipour
authors: Department of Bacteriology & Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Mohammad
authors: M
authors: Kaveh
authors: Department of Bacteriology & Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Hossein
authors: H
authors: Khoshkharam-Roodmajani
mesh_terms: D001427:Bacterial Toxins / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics; D004768:Enterotoxins / Q000235:genetics*; D005798:Genes, Bacterial / Q000235:genetics; D005838:Genotype; D006784:Hospitals, Teaching; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000235:genetics / Q000302:isolation & purification; D016133:Polymerase Chain Reaction; D013211:Staphylococcus aureus / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D018089:Superantigens / Q000235:genetics*; D037521:Virulence Factors / Q000235:genetics*
chemical_list: D001427:Bacterial Toxins; D004269:DNA, Bacterial; D004768:Enterotoxins; D018089:Superantigens; D037521:Virulence Factors; C030107:enterotoxin F, Staphylococcal