title: Catalyst-controlled reverse selectivity in C-C bond formation: NHC-Cu-catalyzed α-selective allylic alkylation with organolithium reagents.
abstract: An efficient and highly α-selective copper-catalyzed allylic alkylation of allylic halides with organolithium reagents is presented. The use of N-heterocyclic carbenes as ligands is key to reverse the common γ-selectivity of this transformation and gives rise to the corresponding linear products with high levels of regioselectivity.
authors: Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands. b.l.feringa@rug.nl.
authors: Stefano F
authors: SF
authors: Pizzolato
authors: Massimo
authors: M
authors: Giannerini
authors: Pieter H
authors: PH
authors: Bos
authors: Martín
authors: M
authors: Fañanás-Mastral
authors: Ben L
authors: BL
authors: Feringa