title: A double-enhanced strip biosensor for the rapid and ultrasensitive detection of protein biomarkers.
abstract: Combining the specific molecular recognition reaction between biotin and streptavidin with a dual-class signal amplification system, containing the unique optical properties of gold nanoparticles and the catalytic reaction of horseradish peroxidase, a double-enhanced strip biosensor was designed for the first time for a visual and rapid detection of protein biomarkers with good accuracy, especially for CEA with a detection limit of 2.9 fg mL(-1).
authors: Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, P. R. China. wangsf@hubu.edu.cn.
authors: Chunyan
authors: C
authors: Qin
authors: Wei
authors: W
authors: Wen
authors: Xiuhua
authors: X
authors: Zhang
authors: Haoshuang
authors: H
authors: Gu
authors: Shengfu
authors: S
authors: Wang
mesh_terms: D015415:Biomarkers / Q000032:analysis / Q000737:chemistry; D015374:Biosensing Techniques; D006046:Gold / Q000737:chemistry; D006735:Horseradish Peroxidase / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry; D018396:Mucin-1 / Q000032:analysis* / Q000737:chemistry; D013917:Thrombin / Q000032:analysis* / Q000737:chemistry
chemical_list: D015415:Biomarkers; D018396:Mucin-1; D006046:Gold; D006735:Horseradish Peroxidase; D013917:Thrombin