title: Cycloserine induced psychosis with hepatic dysfunction.
abstract: With the increase in the cases of multidrug resistance tuberculosis, second line anti-tubercular drugs like the cycloserine are being prescribed frequently. Isoniazid and ethambutol are reported to cause psychosis like state; however, few reports of cycloserine induced psychosis are available. To the best of our knowledge, this is the first case of cycloserine induced psychosis with hepatic dysfunction.
authors: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors: Vishal R
authors: VR
authors: Tandon
authors: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors: Neelam
authors: N
authors: Rani
authors: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors: Roshi
authors: Department of Pulmonary Medicine, Government Medical College, Jammu, Jammu and Kashmir, India.
authors: Rahul
authors: R
authors: Gupta
authors: Department of Psychiatry, Government Medical College, Jammu, Jammu and Kashmir, India.
authors: Manu
authors: M
authors: Arora
authors: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors: Vijay
authors: V
authors: Khajuria
authors: Department of Pharmacology and Therapeutics, Government Medical College, Jammu, Jammu and Kashmir, India.
authors: Vivek
authors: V
authors: Mahajan
mesh_terms: D000904:Antibiotics, Antitubercular / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003523:Cycloserine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D011605:Psychoses, Substance-Induced / Q000209:etiology* / Q000378:metabolism / Q000523:psychology; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
chemical_list: D000904:Antibiotics, Antitubercular; D014150:Antipsychotic Agents; D003523:Cycloserine
keywords: Anti-tubercular treatment; cycloserine; multidrug resistant tuberculosis; psychosis