title: Cardiopulmonary response to exercise in COPD and overweight patients: relationship between unloaded cycling and maximal oxygen uptake profiles.
abstract: Cardiopulmonary response to unloaded cycling may be related to higher workloads. This was assessed in male subjects: 18 healthy sedentary subjects (controls), 14 hypoxemic patients with chronic obstructive pulmonary disease (COPD), and 31 overweight individuals (twelve were hypoxemic). They underwent an incremental exercise up to the maximal oxygen uptake (VO2max), preceded by a 2 min unloaded cycling period. Oxygen uptake (VO2), heart rate (HR), minute ventilation (VE), and respiratory frequency (fR) were averaged every 10 s. At the end of unloaded cycling period, HR increase was significantly accentuated in COPD and hypoxemic overweight subjects (resp., +14 ± 2 and +13 ± 1.5 min(-1), compared to +7.5 ± 1.5 min(-1) in normoxemic overweight subjects and +8 ± 1.8 min(-1) in controls). The fR increase was accentuated in all overweight subjects (hypoxemic: +4.5 ± 0.8; normoxemic: +3.9 ± 0.7 min(-1)) compared to controls (+2.5 ± 0.8 min(-1)) and COPDs (+2.0 ± 0.7 min(-1)). The plateau VE increase during unloaded cycling was positively correlated with VE values measured at the ventilatory threshold and VO2max. Measurement of ventilation during unloaded cycling may serve to predict the ventilatory performance of COPD patients and overweight subjects during an exercise rehabilitation program.
authors: Service des Explorations Fonctionnelles Respiratoires, Hopital Nord (Assistance Publique-Hôpitaux de Marseille) and UMR MD2, Faculté de Médecine Secteur Nord, Boulevard Pierre Dramard, 13916 Cedex 20 Marseille, France ; Laboratory of Physiology, Faculty of Medicine, University of Cheikh Anta Diop, Dakar, P.O. Box 45698, Dakar Fann, Dakar, Senegal ; Unité Mixte Internationale Environnement, Santé, Sociétés (UMI3189 ESS), Université Cheikh Anta Diop (UCAD), P.O. Box 5005, Dakar Fann, Senegal.
authors: Abdoulaye
authors: A
authors: Ba
authors: Service des Explorations Fonctionnelles Respiratoires, Hopital Nord (Assistance Publique-Hôpitaux de Marseille) and UMR MD2, Faculté de Médecine Secteur Nord, Boulevard Pierre Dramard, 13916 Cedex 20 Marseille, France.
authors: Fabienne
authors: F
authors: Brégeon
authors: Service des Explorations Fonctionnelles Respiratoires, Hopital Nord (Assistance Publique-Hôpitaux de Marseille) and UMR MD2, Faculté de Médecine Secteur Nord, Boulevard Pierre Dramard, 13916 Cedex 20 Marseille, France.
authors: Stéphane
authors: S
authors: Delliaux
authors: Laboratory of Physiology, Faculty of Medicine, University of Cheikh Anta Diop, Dakar, P.O. Box 45698, Dakar Fann, Dakar, Senegal.
authors: Fallou
authors: F
authors: Cissé
authors: Laboratory of Physiology, Faculty of Medicine, University of Cheikh Anta Diop, Dakar, P.O. Box 45698, Dakar Fann, Dakar, Senegal ; Unité Mixte Internationale Environnement, Santé, Sociétés (UMI3189 ESS), Université Cheikh Anta Diop (UCAD), P.O. Box 5005, Dakar Fann, Senegal.
authors: Abdoulaye
authors: A
authors: Samb
authors: Service des Explorations Fonctionnelles Respiratoires, Hopital Nord (Assistance Publique-Hôpitaux de Marseille) and UMR MD2, Faculté de Médecine Secteur Nord, Boulevard Pierre Dramard, 13916 Cedex 20 Marseille, France.
authors: Yves
authors: Y
authors: Jammes
mesh_terms: D000328:Adult; D001642:Bicycling; D005081:Exercise Therapy; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D050177:Overweight / Q000378:metabolism / Q000503:physiopathology* / Q000534:rehabilitation; D010101:Oxygen Consumption; D029424:Pulmonary Disease, Chronic Obstructive / Q000378:metabolism / Q000503:physiopathology* / Q000534:rehabilitation