title: Prognostic value of copeptin in patients with acute stroke.
abstract: BACKGROUND
  There is a need to improve stroke care through the prompt identification of stroke patients at increased risk of an adverse outcome.
  
  
  OBJECTIVE
  To evaluate the prognostic value of copeptin in patients with stroke.
  
  
  METHODS
  We systematically searched PubMed and Embase for relevant studies. Poor outcome and mortality were analyzed.
  
  
  RESULTS
  Twelve studies, containing 2682 patients, were included. Pooled analysis showed that copeptin is an independent prognostic marker of poor outcome after acute stroke and there is a borderline effect of copeptin in predicting mortality after acute stroke.
  
  
  CONCLUSIONS
  Copeptin is an independent predictor of poor outcome and mortality for patients with acute stroke.
authors: Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
authors: Lidong
authors: L
authors: Jiao
authors: Changbiao
authors: C
authors: Chu
authors: Shijie
authors: S
authors: Zhou
mesh_terms: D015415:Biomarkers / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006020:Glycopeptides / Q000097:blood*; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D011379:Prognosis; D020521:Stroke / Q000175:diagnosis* / Q000188:drug therapy / Q000401:mortality*; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D006020:Glycopeptides; C048197:copeptins
keywords: acute stroke; copeptin; prognosis; systematic review