title: Focal choroidal excavation in patients with central serous chorioretinopathy.
abstract: OBJECTIVE
  To evaluate the prevalence and clinical features of focal choroidal excavation (FCE) in patients presenting with central serous chorioretinopathy (CSC).
  
  
  METHODS
  This is a retrospective consecutive case series of consecutive patients with CSC who were referred for spectral domain optical coherence tomography (SD-OCT) between January 2010 and December 2011. Medical records were reviewed and clinical features including presence of FCE in SD-OCT, fluorescence angiography (FA), and indocyanine green angiography (ICGA) were studied.
  
  
  RESULTS
  Among the 116 CSC patients assessed, FCE was found in 11 eyes of 7 (6.0%) patients. FCE was associated with subretinal fluid in six eyes of six patients and serous pigment epithelial detachment in three eyes of two patients. The mean central subfield retinal thickness of CSC eyes with FCE was 283.7 μm, compared with 377.5 μm for CSC eyes without FCE (Mann-Whitney U-test, P=0.020). Five FCE eyes of five patients had focal leakage on FA. Choroidal hyperpermeability on ICGA was found in seven CSC eyes with FCE, with four eyes showing hypofluorescent spot corresponding to the FCE. After a mean follow-up of 16 months, visual acuity of all 11 eyes with FCE remained stable or improved at the last follow-up.
  
  
  CONCLUSIONS
  FCE is not an uncommon feature in patients with CSC and might be associated with choroidal hemodynamic disturbances.
authors: 1] Hong Kong Eye Hospital, Hong Kong SAR, China [2] Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
authors: F O J
authors: FO
authors: Luk
authors: 1] Hong Kong Eye Hospital, Hong Kong SAR, China [2] Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
authors: A C T
authors: AC
authors: Fok
authors: 1] Hong Kong Eye Hospital, Hong Kong SAR, China [2] Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
authors: A
authors: A
authors: Lee
authors: 1] Hong Kong Eye Hospital, Hong Kong SAR, China [2] Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
authors: A T W
authors: AT
authors: Liu
authors: Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.
authors: T Y Y
authors: TY
authors: Lai
mesh_terms: D000328:Adult; D000368:Aged; D056833:Central Serous Chorioretinopathy / Q000150:complications / Q000473:pathology*; D002829:Choroid / Q000002:abnormalities*; D015862:Choroid Diseases / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000473:pathology; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity
chemical_list: D007208:Indocyanine Green