title: Comparison of primary radiation versus robotic surgery plus adjuvant radiation in high-risk prostate cancer: a single center experience.
abstract: OBJECTIVE
  The objective of this study was to compare robotic-prostatectomy plus adjuvant radiation therapy (RPRAT) versus primary RT for high-risk prostate cancer (HRPCa).
  
  
  METHODS
  A retrospective chart review was performed for the HRPCa patients treated in our institution between 2000 and 2010. One hundred and twenty-three patients with high-risk disease were identified. The Chi-square test and Fisher's exact test were used to compare local control and distant failure rates between the two treatment modalities. For prostate-specific antigen comparisons between groups, Wilcoxon rank-sum test was used.
  
  
  RESULTS
  The median follow-up was 49 months (range: 3-138 months). Local control, biochemical recurrence rate, distant metastasis, toxicity, and disease-free survival were similar in the two groups.
  
  
  CONCLUSIONS
  Primary RT is an excellent treatment option in patients with HRPCa, is equally effective and less expensive treatment compared with RPRAT. A prospective randomized study is required to guide treatment for patients with HRPCa.
authors: Prabhsimranjot
authors: P
authors: Singh
authors: Prashant
authors: P
authors: Desai
authors: Shruthi
authors: S
authors: Arora
authors: Anthony H
authors: AH
authors: Pham
authors: A Gabriella
authors: AG
authors: Wernicke
authors: Michael
authors: M
authors: Smith
authors: Dattatreyudu
authors: D
authors: Nori
authors: K S
authors: KS
authors: Clifford Chao
authors: Department of Radiation Oncology, Weill Cornell Medical Center, New York, NY 10065, USA.
authors: Bhupesh
authors: B
authors: Parashar
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D012189:Retrospective Studies; D065287:Robotic Surgical Procedures; D016896:Treatment Outcome