title: The corpus callosum in the diagnosis of multiple sclerosis and other CNS demyelinating and inflammatory diseases.
abstract: Lesions in the corpus callosum (CC) are important radiological clues to the diagnosis of multiple sclerosis (MS), but may also occur in other neuroinflammatory and non-neuroinflammatory conditions. In this article, we discuss the radiological features of lesions within the CC in MS and other central nervous system inflammatory and acquired demyelinating diseases. An understanding of the appearance and location of lesions in the CC is important not only for accurate diagnosis and treatment of these various conditions, but as it also provides insights into pathogenesis.
authors: Neuroimmunology Clinic, Concord Hospital and University of Sydney, Sydney, New South Wales, Australia.
authors: Nidhi
authors: N
authors: Garg
authors: Neuroimmunology Clinic, Concord Hospital and University of Sydney, Sydney, New South Wales, Australia.
authors: Stephen W
authors: SW
authors: Reddel
authors: Department of Neuroinflammation, UCL Institute of Neurology, Queen Square MS Centre, London, UK.
authors: David H
authors: DH
authors: Miller
authors: Department of Neuroinflammation, UCL Institute of Neurology, Queen Square MS Centre, London, UK.
authors: Jeremy
authors: J
authors: Chataway
authors: Neuroimmunology Clinic, Concord Hospital and University of Sydney, Sydney, New South Wales, Australia.
authors: D Sean
authors: DS
authors: Riminton
authors: Department of Radiology, St Vincent's Hospital, Sydney, New South Wales, Australia Sydney Neuroimaging Analysis Centre, Sydney, New South Wales, Australia.
authors: Yael
authors: Y
authors: Barnett
authors: Department of Neuroradiology, Southern Radiology, Miranda, Australia.
authors: Lynette
authors: L
authors: Masters
authors: Sydney Neuroimaging Analysis Centre, Sydney, New South Wales, Australia Brain & Mind Research Institute, University of Sydney, New South Wales, Australia.
authors: Michael H
authors: MH
authors: Barnett
authors: Neuroimmunology Clinic, Concord Hospital and University of Sydney, Sydney, New South Wales, Australia Brain & Mind Research Institute, University of Sydney, New South Wales, Australia.
authors: Todd A
authors: TA
authors: Hardy
mesh_terms: D003337:Corpus Callosum / Q000473:pathology*; D003711:Demyelinating Diseases / Q000175:diagnosis / Q000473:pathology*; D004660:Encephalitis / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000473:pathology*
keywords: MRI; MULTIPLE SCLEROSIS; NEUROIMMUNOLOGY; VASCULITIS