title: Parathyroid gland autotransplantation after total thyroidectomy in surgical management of hypopharyngeal and laryngeal carcinomas: A case series.
abstract: OBJECTIVE
  Total thyroidectomy is indicated in most cases with postcricoid carcinoma, circumferential hypopharyngeal carcinoma and in advanced laryngeal carcinoma. Persistent hypoparathyroidism is a frequent complication after total thyroidectomy which is difficult to manage unlike hypothyroidism. This study was to assess the feasibility of parathyroid gland autotranplantation after total thyroidectomy in advanced carcinomas and their effectiveness in preventing persistent hypoparathyroidism.
  
  
  METHODS
  This study included 26 patients with hypopharyngeal and laryngeal carcinoma presented to National Cancer Institute, Cairo University. Total thyroidectomy and total parathyroid gland excision were performed as a part of adequate oncologic surgical procedure. The parathyroid glands were identified, resected and stored in iced saline. Histological confirmation was necessary before implantation into separated muscle pockets in the anterior forearm muscles. Regular samples were drawn to assess serum parathormone and calcium levels.
  
  
  RESULTS
  All patients experienced hypocalcaemia within 1-5 days after operation. Only one patient experienced parathyroid graft failure while the remaining patients were normocalcemic during follow up after surgery, indicating functioning parathyroid grafts.
  
  
  CONCLUSIONS
  Parathyroid gland autotranplantation is a simple safe technique with high success rate in preventing persistent hypoparathyroidism after total thyroidectomy in surgical management of advanced hypopharyngeal and laryngeal carcinomas.
authors: Department of Surgery, National Cancer Institute, Cairo University, Cairo, Egypt.
authors: Abd Elmaksoud M
authors: AE
authors: Abd Elmaksoud
authors: Department of Surgical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt.
authors: Iman G
authors: IG
authors: Farahat
authors: Department of Clinical Pathology, National Cancer Institute, Cairo University, Cairo, Egypt.
authors: Mahmoud M
authors: MM
authors: Kamel
keywords: Autotransplantation; Carcinoma; Hypopharyngeal; Laryngeal; Parathyroid