title: Synthesis of benzoxazole derivatives of honokiol as insecticidal agents against Mythimna separata Walker.
abstract: A series of novel benzoxazole compounds derived from a naturally occurring neolignan honokiol were prepared. Their insecticidal activity was tested against the pre-third-instar larvae of oriental armyworm (Mythimna separata Walker) in vivo. Most of the tested derivatives exhibited more potential insecticidal activity than their precursor honokiol at the concentration of 1mg/mL. Especially compound 6e, containing 4-acetyloxyphenyl groups at the C8 and C8' positions, displayed the most potent insecticidal activity with the final mortality rate of 62.1%.
authors: Research Institute of Pesticidal Design & Synthesis, College of Science, Northwest A&F University, Yangling 712100, Shaanxi Province, China.
authors: Chun
authors: C
authors: Yang
authors: Research Institute of Pesticidal Design & Synthesis, College of Science, Northwest A&F University, Yangling 712100, Shaanxi Province, China.
authors: Xiaoyan
authors: X
authors: Zhi
authors: Research Institute of Pesticidal Design & Synthesis, College of Science, Northwest A&F University, Yangling 712100, Shaanxi Province, China. Electronic address: orgxuhui@nwsuaf.edu.cn.
authors: Hui
authors: H
authors: Xu
mesh_terms: D000818:Animals; D001583:Benzoxazoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000737:chemistry*; D007306:Insecticides / Q000138:chemical synthesis / Q000494:pharmacology; D007814:Larva / Q000187:drug effects; D017705:Lignans / Q000737:chemistry*; D015394:Molecular Structure; D009036:Moths / Q000187:drug effects*; D000498:Allyl Compounds; D010636:Phenols
chemical_list: D001583:Benzoxazoles; D001713:Biphenyl Compounds; D007306:Insecticides; D017705:Lignans; C005499:honokiol; D000498:Allyl Compounds; D010636:Phenols
keywords: Benzoxazole; Honokiol; Insecticidal activity; Mythimna separata Walker