title: Challenges of malnutrition care among HIV-infected children on antiretroviral treatment in Africa.
abstract: More than 90% of the estimated 3.2 million children with HIV worldwide, at the end of 2013, were living in sub-Saharan Africa. The management of these children was still difficult in 2014 despite the progress in access to antiretroviral drugs. A great number of HIV-infected children are not diagnosed at 6 weeks and start antiretroviral treatment late, at an advanced stage of HIV disease complicated by other comorbidities such as malnutrition. Malnutrition is a major problem in the sub-Saharan Africa global population; it is an additional burden for HIV-infected children because they do not respond as well as non-infected children to the usual nutritional care. HIV infection and malnutrition interact, creating a vicious circle. It is important to understand the relationship between these 2 conditions and the effect of antiretroviral treatment on this circle to taking them into account for an optimal management of pediatric HIV. An improved monitoring of growth during follow-up and the introduction of a nutritional support among HIV-infected children, especially at antiretroviral treatment initiation, are important factors that could improve response to antiretroviral treatment and optimize the management of pediatric HIV in resource-limited countries.
authors: Inserm, centre de recherche U897, épidémiologie et biostatistiques, institut de santé publique, d'épidémiologie et de développement (ISPED), université de Bordeaux - CS61292, 146, rue Léo-Saignat, 33076 Bordeaux cedex, France. Electronic address: Julie.Jesson@isped.u-bordeaux2.fr.
authors: J
authors: J
authors: Jesson
authors: Inserm, centre de recherche U897, épidémiologie et biostatistiques, institut de santé publique, d'épidémiologie et de développement (ISPED), université de Bordeaux - CS61292, 146, rue Léo-Saignat, 33076 Bordeaux cedex, France.
authors: V
authors: V
authors: Leroy
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control; D000293:Adolescent; D017954:Africa South of the Sahara / Q000453:epidemiology; D000740:Anemia / Q000209:etiology; D000886:Anthropometry; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D002648:Child; D015362:Child Nutrition Disorders / Q000453:epidemiology* / Q000276:immunology / Q000628:therapy; D002675:Child, Preschool; D015897:Comorbidity; D003906:Developing Countries; D019587:Dietary Supplements; D018450:Disease Progression; D005260:Female; D006130:Growth Disorders / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D015658:HIV Infections / Q000151:congenital / Q000188:drug therapy* / Q000453:epidemiology; D019247:HIV Wasting Syndrome / Q000453:epidemiology / Q000276:immunology; D006301:Health Services Needs and Demand; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D007228:Infant Nutrition Disorders / Q000453:epidemiology* / Q000276:immunology / Q000628:therapy; D007231:Infant, Newborn; D008297:Male; D009752:Nutritional Status; D018529:Nutritional Support; D015995:Prevalence; D012306:Risk
chemical_list: D019380:Anti-HIV Agents
keywords: Africa; Afrique; Child; Enfant; HIV; Malnutrition; Retard de croissance; Stunting; VIH