title: Sarcoidosis presenting as severe renin-dependent hypertension due to kidney vascular injury.
abstract: Renal sarcoidosis embraces a wide variety of clinical patterns. Renal vascular involvement has seldom been reported and usually in the setting of systemic vasculitis. We report the case of a 22-year-old patient in whom inaugural manifestation of renal sarcoidosis consisted of severe hypertension associated with bilateral perfusion defects and tumour-like nodules. In the setting of renal sarcoidosis, our case suggests that renin-dependant hypertension may arise from renal ischaemia as a result of extrinsic compression of kidney blood vessels due to severe granulomatous inflammation.
authors: Hypertension Unit , Université Paris Descartes, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou , Paris Cedex 15 , France.
authors: Cedric
authors: C
authors: Rafat
authors: Hypertension Unit , Université Paris Descartes, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou , Paris Cedex 15 , France.
authors: Guillaume
authors: G
authors: Bobrie
authors: Hypertension Unit , Université Paris Descartes, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou , Paris Cedex 15 , France.
authors: Antoine
authors: A
authors: Chedid
authors: Department of Pathology , Université Paris Descartes, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou , Paris Cedex 15 , France.
authors: Dominique
authors: D
authors: Nochy
authors: Department of Radiology , Université Paris Descartes, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou , Paris Cedex 15 , France.
authors: Anne
authors: A
authors: Hernigou
authors: Hypertension Unit , Université Paris Descartes, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou , Paris Cedex 15 , France.
authors: Pierre-François
authors: PF
authors: Plouin
keywords: granulomatous vasculitis; hypertension; sarcoidosis; secondary hyperaldosteronism; tubulointerstitial nephritis