title: Revision of biological methods for determination of EDC presence and their endocrine potential.
abstract: Endocrine-disrupting compounds (EDC) are chemicals responsible for disturbances in the hormonal balance of organisms. This group of chemicals includes both egzogenic and endogenic substances or their mixtures that impact functioning of natural hormones in organisms. In the available literature one can find information on the application of chromatographic and related techniques in the analysis of environmental samples for detection, identification, and quantitation of a wide spectrum of chemicals posing endocrine properties. On the other hand, more and more biotests are being developed to determine endocrine potency of environmental samples due to development of genetic engineering methods and specific detection methods of cells' response to the action of particular chemicals of interest. This article presents revisions of the most novel methods for this potency determination with application to biological elements.
authors: a Department of Analytical Chemistry, Faculty of Chemistry , Gdańsk University of Technology , Gdańsk , Poland.
authors: Błażej
authors: B
authors: Kudłak
authors: Natalia
authors: N
authors: Szczepańska
authors: Katarzyna
authors: K
authors: Owczarek
authors: Zofia
authors: Z
authors: Mazerska
authors: Jacek
authors: J
authors: Namieśnik
mesh_terms: D000818:Animals; D052244:Endocrine Disruptors / Q000032:analysis* / Q000494:pharmacology*; D004784:Environmental Monitoring / Q000379:methods; D004785:Environmental Pollutants / Q000032:analysis* / Q000494:pharmacology*; D006801:Humans
chemical_list: D052244:Endocrine Disruptors; D004785:Environmental Pollutants
keywords: bioindicators; biotests; endocrine-disrupting chemicals; hormones; pharmaceuticals; trace organic pollutants