title: Current challenges and pitfalls in the pharmacological treatment of depression.
abstract: The multifactorial etiology of depression obliges needs an individual assessment, the psychopharmacological approach involving a biopsychosocial analysis for each individual case. The rebalancing of the depressive patient, seen as a return to a normal level of psychosocial functioning and reduced risk of relapse is achieved with a prompt and constant support of specialized teams. Treatment should include psychopharmacological and psychosocial approaches, the results being interrelated and contributing to the prognosis of the disorder. Progress in clinical and pharmacological research, vivid dynamics of socio-economic environment, the complexity of diagnostic evaluation and the need for an interdisciplinary approach may cause difficulties in addressing the depressive patient and the ethical controversies. The aim of this paper is to present a brief analysis of challenges encountered in the present psychiatric practice, starting from the heterogeneity of depressive manifestations and finishing with the prioritization of interventional forms.
authors: Department of Medical Psychology, "Carol Davila" University of Medicine and Pharmacy, Bucharest.
authors: O
authors: O
authors: Popa-Velea
authors: "Carol Davila" University of Medicine and Pharmacy, Bucharest.
authors: I R
authors: IR
authors: Gheorghe
authors: Department of Medical Psychology, "Carol Davila" University of Medicine and Pharmacy, Bucharest.
authors: C I
authors: CI
authors: Truţescu
authors: Department of Marketing, "Carol Davila" University of Medicine and Pharmacy, Bucharest.
authors: V L
authors: VL
authors: Purcărea
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use*; D015897:Comorbidity; D003863:Depression / Q000145:classification / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents
keywords: depression; medication; therapy