title: [A newly-defined entity: combined pulmonary fibrosis and emphysema syndrome].
abstract: Combined pulmonary fibrosis and emphysema (CPFE) syndrome is a rare disease characterized with shortness of breath, upper lobe emphysema, lower lobe fibrosis and impairment of gas exchange. This syndrome is a disease usually seen in male smokers. Pulmonary hypertension is associated with mortality. Another important feature, spirometric volumes relatively protected and a reduction in carbon monoxide diffusion test. CPFE syndrome in the literature so far have been identified in only 70 patients. In this review CPFE syndrome is presented with literature.
authors: Department of Chest Diseases, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey. ozcelik.nesli@gmail.com.
authors: Neslihan
authors: N
authors: Özçelik
authors: Savaş
authors: S
authors: Özsu
mesh_terms: D000369:Aged, 80 and over; D002248:Carbon Monoxide; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000401:mortality; D008168:Lung / Q000503:physiopathology; D008297:Male; D011656:Pulmonary Emphysema / Q000150:complications* / Q000209:etiology / Q000628:therapy; D011658:Pulmonary Fibrosis / Q000150:complications* / Q000209:etiology / Q000628:therapy; D012907:Smoking / Q000009:adverse effects; D013147:Spirometry; D013577:Syndrome
chemical_list: D002248:Carbon Monoxide