title: Osteoporosis prescribing in long-term care: impact of a provincial knowledge translation strategy.
abstract: This study described prescribing trends before and after implementing a provincial strategy aimed at improving osteoporosis and fracture prevention in Ontario long-term care (LTC) homes. Data were obtained from a pharmacy provider for 10 LTC homes in 2007 and 166 homes in 2012. We used weighted, multiple linear regression analyses to examine facility-level changes in vitamin D, calcium, and osteoporosis medication prescribing rates between 2007 and 2012. After five years, the estimated increase in vitamin D, calcium, and osteoporosis medication prescribing rates, respectively, was 38.2 per cent (95% confidence interval [CI]: 29.0, 47.3; p < .001), 4.0 per cent (95% CI: -3.9, 12.0; p = .318), and 0.2 per cent (95% CI: -3.3, 3.7; p = .91). Although the study could not assess causality, findings suggest that wide-scale knowledge translation activities successfully improved vitamin D prescribing rates, although ongoing efforts are needed to target homes with low uptake.
authors: Department of Medicine,McMaster University.
authors: Courtney C
authors: CC
authors: Kennedy
authors: Department of Medicine,McMaster University.
authors: George
authors: G
authors: Ioannidis
authors: Clinical Epidemiology and Biostatistics,McMaster University.
authors: Lehana
authors: L
authors: Thabane
authors: Department of Medicine,McMaster University.
authors: Jonathan D
authors: JD
authors: Adachi
authors: Medical Pharmacies Group Limited.
authors: Denis
authors: D
authors: O'Donnell
authors: Department of Kinesiology,University of Waterloo.
authors: Lora M
authors: LM
authors: Giangregorio
authors: Department of Medicine,McMaster University.
authors: Laura E
authors: LE
authors: Pickard
authors: Department of Medicine,McMaster University.
authors: Alexandra
authors: A
authors: Papaioannou
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D002118:Calcium / Q000627:therapeutic use; D015331:Cohort Studies; D005260:Female; D006291:Health Policy; D006801:Humans; D016014:Linear Models; D008134:Long-Term Care; D008297:Male; D015999:Multivariate Analysis; D009735:Nursing Homes; D009864:Ontario; D010024:Osteoporosis / Q000188:drug therapy*; D058866:Osteoporotic Fractures / Q000517:prevention & control*; D010818:Practice Patterns, Physicians'; D057170:Translational Research, Biomedical; D014807:Vitamin D / Q000627:therapeutic use
chemical_list: D050071:Bone Density Conservation Agents; D014807:Vitamin D; D002118:Calcium
keywords: l'ostéoporose