title: [MicroRNA and cancer].
abstract: Review is devoted to analysis of the role of microRNA in progression of human tumors. The following aspects of this problem are discussed: general characteristics of microRNA, expression pattern of these RNAs in human tumors and specificity of this expression, putative role of microRNAs as oncogenes and tumor suppressors for tumor growth, participation of microRNAs in induction of transformed phenotypes of tumor cells, possible role of microRNAs for early diagnosis of the disease and prognosis.
authors: F L
authors: FL
authors: Kiselev
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000235:genetics* / Q000378:metabolism; D002471:Cell Transformation, Neoplastic / Q000235:genetics* / Q000473:pathology; D042241:Early Diagnosis; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism; D009369:Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D009928:Organ Specificity; D011379:Prognosis; D015398:Signal Transduction
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D035683:MicroRNAs