title: Whole genome sequencing in pharmacogenomics.
abstract: Pharmacogenomics aims to shed light on the role of genes and genomic variants in clinical treatment response. Although, several drug-gene relationships are characterized to date, many challenges still remain toward the application of pharmacogenomics in the clinic; clinical guidelines for pharmacogenomic testing are still in their infancy, whereas the emerging high throughput genotyping technologies produce a tsunami of new findings. Herein, the potential of whole genome sequencing on pharmacogenomics research and clinical application are highlighted.
authors: Department of Pharmacy, School of Health Sciences, University of Patras Patras, Greec.
authors: Theodora
authors: T
authors: Katsila
authors: Department of Pharmacy, School of Health Sciences, University of Patras Patras, Greec.
authors: George P
authors: GP
authors: Patrinos
keywords: genome-wide association studies; genotype; pesonalized medicine; pharmacogenomics; pharmacogenomics biomarkers; whole genome sequencing