title: The need for improved uptake of the KDIGO glomerulonephritis guidelines into clinical practice in Canada: a survey of nephrologists.
abstract: BACKGROUND
  The lack of glomerulonephritis (GN) guidelines has historically contributed to substantial variability in the treatment of GN. We hypothesize that there are barriers to GN guideline implementation leading to incomplete translation of the 2012 KDIGO GN guidelines into patient care, and that current practice patterns deviate from guideline recommendations.
  
  
  METHODS
  Adult nephrologists in Canada (N = 390) were surveyed using a web-based tool. The survey of 40 questions captured physician demographics, self-reported GN case load, treatment approaches and barriers to guideline implementation.
  
  
  RESULTS
  The response rate was 44%. Physicians report seeing six (IQR 4,10) new cases of idiopathic GN every 6 months. The majority treat ANCA GN according to guidelines, but 9-37% treat nephrotic focal segmental glomerulosclerosis or membranous nephropathy with non-recommended immunosuppression and 6-9% do not treat with any immunotherapy, whereas 26% treat subnephrotic disease with immunosuppression. The majority indicated that standardized care tools would improve patient care, but they were only available to 25-44%. Patient education tools and nursing support are unavailable to 87 and 67%, respectively; insurance coverage for immune therapies is poorly accessible to 84%, yet 86% feel this would improve care and 96% of physicians support comparing their practice with benchmarks from provincial GN registries.
  
  
  CONCLUSIONS
  We show that 2 years after the publication of the KDIGO GN guidelines, 15-46% of Canadian nephrologists report treatment strategies not in keeping with guideline recommendations. We identify barriers to guideline implementation and widespread physician support for initiatives that address these barriers to improve patient care.
authors: Division of Nephrology , University of British Columbia , Vancouver , BC , Canada ; BC Provincial Renal Agency , Vancouver , BC , Canada ; Centre for Health Evaluation and Outcomes Research , St. Paul's Hospital , Vancouver , BC , Canada.
authors: Sean
authors: S
authors: Barbour
authors: Division of Nephrology , University of British Columbia , Vancouver , BC , Canada ; BC Provincial Renal Agency , Vancouver , BC , Canada ; Centre for Health Evaluation and Outcomes Research , St. Paul's Hospital , Vancouver , BC , Canada.
authors: Monica
authors: M
authors: Beaulieu
authors: Division of Nephrology , University of British Columbia , Vancouver , BC , Canada ; BC Provincial Renal Agency , Vancouver , BC , Canada ; Centre for Health Evaluation and Outcomes Research , St. Paul's Hospital , Vancouver , BC , Canada.
authors: Jagbir
authors: J
authors: Gill
authors: BC Provincial Renal Agency , Vancouver , BC , Canada.
authors: Gabriela
authors: G
authors: Espino-Hernandez
authors: Division of Nephrology , University of Toronto , Toronto , ON , Canada.
authors: Heather N
authors: HN
authors: Reich
authors: Division of Nephrology , University of British Columbia , Vancouver , BC , Canada ; BC Provincial Renal Agency , Vancouver , BC , Canada ; Centre for Health Evaluation and Outcomes Research , St. Paul's Hospital , Vancouver , BC , Canada.
authors: Adeera
authors: A
authors: Levin
keywords: KDIGO; care gap; glomerulonephritis; guideline implementation; knowledge translation