title: Quantifying the Burden of Revision Total Joint Arthroplasty for Periprosthetic Infection.
abstract: Periprosthetic joint infection (PJI) represents substantial clinical and economic burdens. This study evaluated patient and procedure characteristics and resource utilization associated with revision arthroplasty for PJI. The Nationwide Inpatient Sample (Q4 2005-2010) was analyzed for 235,857 revision THA (RTHA) and 301,718 revision TKA (RTKA) procedures. PJI was the most common indication for RTKA, and the third most common reason for RTHA. PJI was most commonly associated with major severity of illness (SOI) in RTHA, and with moderate SOI in RTKA. RTHA and RTKA for PJI had the longest length of stay. Costs were higher for RTHA/RTKA for PJI than for any other diagnosis except periprosthetic fracture. Epidemiologic differences exist in the rank, severity and populations for RTHA and RTKA for PJI.
authors: Department of Orthopaedic Surgery, Pennsylvania Hospital, Philadelphia, Pennsylvania.
authors: Atul F
authors: AF
authors: Kamath
authors: Exponent, Inc., Philadelphia, Pennsylvania.
authors: Kevin L
authors: KL
authors: Ong
authors: Exponent, Inc., Menlo Park, California.
authors: Edmund
authors: E
authors: Lau
authors: Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California; Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, California.
authors: Vanessa
authors: V
authors: Chan
authors: Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California.
authors: Thomas P
authors: TP
authors: Vail
authors: Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts.
authors: Harry E
authors: HE
authors: Rubash
authors: Department of Orthopaedic Surgery, Mayo Clinic, SW, Rochester, Minnesota.
authors: Daniel J
authors: DJ
authors: Berry
authors: Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California; Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, California.
authors: Kevin J
authors: KJ
authors: Bozic
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects* / Q000191:economics*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects* / Q000191:economics*; D005260:Female; D017048:Health Care Costs; D006801:Humans; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge; D057068:Periprosthetic Fractures; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000191:economics*; D012086:Reoperation / Q000191:economics*; D014481:United States
keywords: epidemiology; infection; revision arthroplasty; total hip arthroplasty (replacement); total knee arthroplasty