title: Reperfusion Rates of Pulmonary Arteriovenous Malformations after Coil Embolization: Evaluation with Time-Resolved MR Angiography or Pulmonary Angiography.
abstract: OBJECTIVE
  To assess reperfusion rates after coil embolization for pulmonary arteriovenous malformations (PAVMs) using time-resolved magnetic resonance (MR) angiography or pulmonary angiography.
  
  
  METHODS
  Patients with PAVMs who underwent embolization and met the following inclusion criteria were included: (a) embolization was performed using bare or fibered platinum microcoils or both, (b) the complete cessation of flow was confirmed by digital subtraction angiography, and (c) follow-up examinations were conducted with time-resolved MR angiography or pulmonary angiography. Coil embolization was performed in 16 patients with 24 untreated or reperfused PAVMs. Sac embolization was performed for 12 untreated PAVMs. Feeding artery embolization was performed as primary embolization in each of the 12 reperfused PAVMs. Five PAVMs were treated 2 to 4 times because of reperfusion. The study included 32 coil embolizations. Follow-up images were reviewed, and reperfusion rates were assessed. The relationships between reperfusion and the location of PAVM, size of PAVM (feeding artery and venous sac), coils (number and total length), timing of embolization (primary or repeat embolization), and types of coils used (with or without fibered coils) were examined.
  
  
  RESULTS
  Reperfusion rates at 3, 6, 12, and 24 months were 8%, 27%, 36%, and 49%, respectively, for the 12 untreated PAVMs (primary embolization) and 50%, 50%, 92%, and 100%, respectively, for the 12 reperfused PAVMs (repeat embolization) (P = .0062). No significant differences were observed in the other parameters measured.
  
  
  CONCLUSIONS
  When evaluated with time-resolved MR angiography or pulmonary angiography, reperfusion rates after coil embolization for PAVM were considerably high, particularly with repeat embolization.
authors: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi467-8601, Japan. Electronic address: mshimohira@gmail.com.
authors: Masashi
authors: M
authors: Shimohira
authors: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi467-8601, Japan.
authors: Tatsuya
authors: T
authors: Kawai
authors: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi467-8601, Japan.
authors: Takuya
authors: T
authors: Hashizume
authors: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi467-8601, Japan.
authors: Kengo
authors: K
authors: Ohta
authors: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi467-8601, Japan.
authors: Motoo
authors: M
authors: Nakagawa
authors: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi467-8601, Japan.
authors: Yoshiyuki
authors: Y
authors: Ozawa
authors: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi467-8601, Japan.
authors: Keita
authors: K
authors: Sakurai
authors: Department of Radiology, Nagoya City University Graduate School of Medical Sciences, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi467-8601, Japan.
authors: Yuta
authors: Y
authors: Shibamoto
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction; D001165:Arteriovenous Malformations / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D005260:Female; D006801:Humans; D007564:Japan; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D055420:Perfusion Imaging / Q000379:methods*; D010690:Phlebography / Q000379:methods*; D011237:Predictive Value of Tests; D011651:Pulmonary Artery / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000503:physiopathology; D011652:Pulmonary Circulation; D011667:Pulmonary Veins / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000503:physiopathology; D012189:Retrospective Studies; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult