title: Evaluation of cognitive functions in gestational diabetes mellitus.
abstract: OBJECTIVE
  To evaluate the association between cognitive functions and metabolic status in cases with gestational diabetes mellitus (GDM).
  
  
  METHODS
  In this study 44 patients with GDM and 45 normal pregnant were included. Depression was evaluated with Beck's depression inventory (BDI). Cognitive functions were evaluated with Montreal cognitive assessment (MOCA), paced auditory serial addition test (PASAT), spatial recall test (SRT), symbol digit modalities (SDMT), and word list generation (WLG).
  
  
  RESULTS
  The mean gestational age, educational level and account of previous birth of the subjects in the study were not statistically different between the groups. The mean scores of BDI of the 2 groups were not statistically different. MOCA score and SDMT was significantly decreased in GDM in comparison to NP (p=0.005, p=0.04 respectively). Also, SDMT score was inversely correlated with number of pregnancies, postprandial blood glucose and HbA1c.The scores of PASAT, SRT, SPART and WLG were statistically similar between the groups.
  
  
  CONCLUSIONS
  Our findings may be a clue for early onset of impairment in cognitive functions in cases with new onset diabetes during pregnancy.
authors: Division of Endocrinology-Metabolism and Diabetes, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors: F E
authors: FE
authors: Keskin
authors: Division of Endocrinology-Metabolism and Diabetes, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors: M
authors: M
authors: Ozyazar
authors: Division of Endocrinology-Metabolism and Diabetes, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors: A S
authors: AS
authors: Pala
authors: Department of Neurology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors: A D
authors: AD
authors: Elmali
authors: Department of Neurology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors: B
authors: B
authors: Yilmaz
authors: Department of Neurology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors: U
authors: U
authors: Uygunoglu
authors: Department of Neurology, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors: M
authors: M
authors: Bozluolcay
authors: Department of Gynecology and Obstetrics, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors: A
authors: A
authors: Tuten
authors: Mayis Psychology Center, Istanbul, Turkey.
authors: A
authors: A
authors: Bingöl
authors: Division of Endocrinology-Metabolism and Diabetes, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey.
authors: E
authors: E
authors: Hatipoglu
mesh_terms: D000328:Adult; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology / Q000523:psychology; D003863:Depression / Q000175:diagnosis / Q000523:psychology; D016640:Diabetes, Gestational / Q000523:psychology*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D009483:Neuropsychological Tests; D011247:Pregnancy; D011569:Psychiatric Status Rating Scales