title: Adhesion of Lactobacilli and their anti-infectivity potential.
abstract: The probiotic potential of lactic acid bacteria primarily point toward colonizing ability of Lactobacilli as the most important attribute for endowing all the known beneficial effects in a host. Lactobacillus species exert health-promoting function in the gastrointestinal tract through various mechanisms such as pathogen exclusion, maintenance of microbial balance, immunomodulation, and other crucial functions. It has been seen that many surface layer proteins are involved in host adhesion, and play significant role in the modification of some signaling pathways within the host cells. Interaction between different bacterial cell surface proteins and host receptor has been imperative for a better understanding of the mechanism through which Lactobacilli exert their health-promoting functions.
authors: a Department of Microbiology , National Institute of Nutrition , Hyderabad , India.|b Centre for Molecular Biology, Central University of Jammu , Samba , Jammu & Kashmir , India.
authors: Ashok Kumar
authors: AK
authors: Yadav
authors: c Molecular Biology Unit, Dairy Microbiology Division, National Dairy Research Institute , Karnal , Haryana , India.
authors: Ashish
authors: A
authors: Tyagi
authors: d Department of Biotechnology , Seth Jai Parkash Mukand Lal Institute of Engineering and Technology , Radaur , Yamuna Nagar , Haryana , India.|e Department of Nutrition Biology , Central University of Haryana , Mahendergarh , Haryana , India.
authors: Ashwani
authors: A
authors: Kumar
authors: d Department of Biotechnology , Seth Jai Parkash Mukand Lal Institute of Engineering and Technology , Radaur , Yamuna Nagar , Haryana , India.
authors: Surbhi
authors: S
authors: Panwar
authors: c Molecular Biology Unit, Dairy Microbiology Division, National Dairy Research Institute , Karnal , Haryana , India.
authors: Sunita
authors: S
authors: Grover
authors: f School of Life Sciences, Appejay Satya University , Gurgaon , Haryana , India.
authors: Asha Chandola
authors: AC
authors: Saklani
authors: a Department of Microbiology , National Institute of Nutrition , Hyderabad , India.
authors: Rajkumar
authors: R
authors: Hemalatha
authors: c Molecular Biology Unit, Dairy Microbiology Division, National Dairy Research Institute , Karnal , Haryana , India.
authors: Virender Kumar
authors: VK
authors: Batish
mesh_terms: D000818:Animals; D001422:Bacterial Adhesion; D019317:Evidence-Based Medicine; D005109:Extracellular Matrix / Q000382:microbiology; D000069196:Gastrointestinal Microbiome / Q000276:immunology*; D006790:Host-Parasite Interactions; D006801:Humans; D056747:Immunomodulation; D017053:Infection Control; D007413:Intestinal Mucosa / Q000276:immunology / Q000378:metabolism / Q000382:microbiology; D007778:Lactobacillus / Q000276:immunology / Q000502:physiology*; D056265:Microbial Interactions; D009093:Mucus / Q000382:microbiology; D019936:Probiotics / Q000627:therapeutic use*
keywords: Lactobacilli; colonization; health benefits; surface layer proteins