title: Unusual histological variant of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation.
abstract: Malignant peripheral nerve sheath tumor (MPNST) with rhabdomyoblastic differentiation is called as malignant triton tumor (MTT). It is highly aggressive soft tissue tumor with higher local recurrence rate. MTT has poor prognosis than MPNST. MTT seems to be more aggressive in patients with neurofibromatosis (NF-1). We herein, reporting an interesting case of 55 years male with multiple neurofibromas all over the body since 30 years and multiple café-au-lait spots, diagnosed as NF-1. Since 6 years, he had an enlarged mass in left thigh. Wide excision of mass was done. On histopathological examination revealed the diagnosis of MTT and diagnosis of which was confirmed on immunohistochemistry.
authors: Smita Shete, Saroj Bolde, Gopal Pandit, Pushkar Matkari, Department of Pathology, Dr. Vaishampayan Memorial Government Medical College, Solapur, Maharashtra 4132512, India.
authors: Smita
authors: S
authors: Shete
authors: Smita Shete, Saroj Bolde, Gopal Pandit, Pushkar Matkari, Department of Pathology, Dr. Vaishampayan Memorial Government Medical College, Solapur, Maharashtra 4132512, India.
authors: Saroj
authors: S
authors: Bolde
authors: Smita Shete, Saroj Bolde, Gopal Pandit, Pushkar Matkari, Department of Pathology, Dr. Vaishampayan Memorial Government Medical College, Solapur, Maharashtra 4132512, India.
authors: Gopal
authors: G
authors: Pandit
authors: Smita Shete, Saroj Bolde, Gopal Pandit, Pushkar Matkari, Department of Pathology, Dr. Vaishampayan Memorial Government Medical College, Solapur, Maharashtra 4132512, India.
authors: Pushkar
authors: P
authors: Matkari
authors: Smita Shete, Saroj Bolde, Gopal Pandit, Pushkar Matkari, Department of Pathology, Dr. Vaishampayan Memorial Government Medical College, Solapur, Maharashtra 4132512, India.
authors: Sachin B
authors: SB
authors: Ingle
keywords: Desmin; Malignant triton tumor; Neurofibromatosis-1; S-100 protein