title: Organ preservation review: history of organ preservation.
abstract: OBJECTIVE
  To summarize the history of organ preservation and place into this context the current trends in preservation.
  
  
  RESULTS
  Multiple large retrospective studies have analyzed cold preservation solutions in an attempt to determine superiority with largely negative results. Experimental and some clinical studies have examined machine perfusion of procured grafts, in both hypothermic and normothermic contexts with variable, but promising, results. Lastly, there are experimental efforts to evaluate mesenchymal stem cell therapy on rehabilitation of marginal donor organs.
  
  
  CONCLUSIONS
  New trends in organ preservation may soon translate into more efficient use of the limited donor pool.
authors: aTransplant Surgery Department bGeneral Surgery Department, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
authors: Andrew M
authors: AM
authors: Cameron
authors: Jose F
authors: JF
authors: Barandiaran Cornejo
mesh_terms: D000818:Animals; D003080:Cold Temperature; D015925:Cryopreservation; D006801:Humans; D009926:Organ Preservation / Q000379:methods; D019188:Organ Preservation Solutions; D010477:Perfusion / Q000379:methods; D014019:Tissue Donors
chemical_list: D019188:Organ Preservation Solutions