title: [Heterogeneity and possible structure of mesenchymal stromal cell population].
abstract: Mesenchymal stromal cells (MSC) represent a heterogeneous population of cells that differ in morphology, phenotype, ability to grow and differentiate, and other properties. Differences between MSC are related in part to the influence of their microenvironment. However, the heterogeneity of these cells also is due to their parent-progeny relationship. Hierarchical organization of the MSC population that comprises different categories of oligopotent and multipotent cells, is complicated and poorly understood. This review includes data on morphological, phenotypic and functional heterogeneity of MSC and its possible connection with the population structure.
authors: O V
authors: OV
authors: Paiushina
authors: E I
authors: EI
authors: Domaratskaia
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D002454:Cell Differentiation; D019070:Cell Lineage / Q000235:genetics*; D049109:Cell Proliferation; D060833:Cellular Microenvironment; D002999:Clone Cells; D018740:Genetic Heterogeneity; D005838:Genotype; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000378:metabolism; D039902:Multipotent Stem Cells / Q000166:cytology* / Q000378:metabolism; D010641:Phenotype
chemical_list: D015415:Biomarkers