title: [Non-celiac gluten sensitivity].
abstract: Non-celiac gluten sensitivity has recently been recognized by the scientific community as a part of gluten-related disorders, and is defined as a condition with gastrointestinal and/or extra-intestinal symptoms triggered by gluten ingestion in the absence of celiac disease and wheat allergy. Currently, there is no specific serological marker and non-celiac gluten sensitivity remains a diagnosis of exclusion: testing for celiac disease and wheat allergy must be negative, symptoms must improve with a gluten-free diet, and diagnosis must be confirmed by the gluten challenge. In this article, we discuss current knowledge of pathophysiology, clinical and epidemilogical spectrum, diagnosis, and treatment of NCGS.
authors: Iva
authors: I
authors: Hoffmanová
authors: Daniel
authors: D
authors: Sánchez
mesh_terms: D002446:Celiac Disease / Q000175:diagnosis* / Q000628:therapy*; D055050:Diet, Gluten-Free; D005983:Glutens; D006801:Humans; D021182:Wheat Hypersensitivity / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D005983:Glutens
keywords: celiac disease - FODMAPs - gluten-free diet - gluten-related disorders - irritable bowel syndrome - non-celiac gluten sensitivity - wheat allergy.