title: Larvicidal activity of the essential oil of Youngia japonica aerial parts and its constituents against Aedes albopictus.
abstract: The aim of this study was to evaluate the larvicidal activity of the essential oil of Youngia japonica aerial parts against the larvae of Aedes albopictus and to isolate any active compounds from the oil. Gas chromatography-mass spectrometry (GC-MS) analyses revealed the presence of 31 compounds, with menthol (23.53%), α-asarone (21.54%), 1,8-cineole (5.36%), and caryophyllene (4.45%) as the major constituents. Bioactivity-directed chromatographic separation of the oil led to the isolation of menthol and α-asarone as active compounds. The essential oil of Y. japonica exhibited larvicidal activity against the fourth instar larvae of A. albopictus with an LC₅₀ value of 32.45 μg/mL. α-Asarone and menthol possessed larvicidal activity against the fourth instar larvae of A. albopictus with LC₅₀ values of 24.56 μg/mL and 77.97 μg/mL, respectively. The results indicate that the essential oil of Y. japonica aerial parts and the two constituents can be potential sources of natural larvicides.
authors: Xin Chao
authors: XC
authors: Liu
authors: Qiyong
authors: Q
authors: Liu
authors: Xu Bo
authors: XB
authors: Chen
authors: Qi Zhi
authors: QZ
authors: Liu
authors: Zhi Long
authors: ZL
authors: Liu
mesh_terms: D000330:Aedes / Q000196:embryology*; D000081248:Allylbenzene Derivatives; D000818:Animals; D000840:Anisoles / Q000302:isolation & purification; D019659:Asteraceae / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D007306:Insecticides / Q000302:isolation & purification; D007814:Larva; D008610:Menthol / Q000302:isolation & purification; D009032:Mosquito Control / Q000379:methods*; D009822:Oils, Volatile / Q000302:isolation & purification; D035261:Plant Components, Aerial; D010938:Plant Oils / Q000302:isolation & purification
chemical_list: D000081248:Allylbenzene Derivatives; D000840:Anisoles; D007306:Insecticides; D009822:Oils, Volatile; D010938:Plant Oils; C012195:asarone; D008610:Menthol