title: Lower-limb performance disparities: implications for exercise prescription in multiple sclerosis.
abstract: The purpose of this study was to examine unilateral lower-limb exercise tolerance during fixed-load cycling to quantify performance disparities of the legs. Eight individuals with relapsing-remitting multiple sclerosis (MS) and seven controls performed submaximal single-leg cycling. Individuals with MS performed significantly more work with the stronger leg than the weaker leg (stronger leg: 6.4 +/- 1.7 kJ, weaker leg: 4.7 +/- 2.5 kJ, p = 0.02). The control group displayed no statistical differences between limbs (p = 0.36). These results highlight a need for individualized exercise testing when prescribing training programs for those with MS.
authors: Rebecca D
authors: RD
authors: Larson
authors: Kevin K
authors: KK
authors: McCully
authors: Daniel J
authors: DJ
authors: Larson
authors: William M
authors: WM
authors: Pryor
authors: Lesley J
authors: LJ
authors: White
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005080:Exercise Test; D005081:Exercise Therapy / Q000379:methods*; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D007866:Leg / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000503:physiopathology* / Q000534:rehabilitation*; D018482:Muscle, Skeletal / Q000503:physiopathology; D054792:Muscle, Striated; D010101:Oxygen Consumption
keywords: MS; bilateral; exercise prescription; leg performance; leg performance disparities; lower limb; lower-limb exercise; multiple sclerosis; muscle; work