title: Clustering, climate and dengue transmission.
abstract: Dengue is currently the most rapidly spreading vector-borne disease, with an increasing burden over recent decades. Currently, neither a licensed vaccine nor an effective anti-viral therapy is available, and treatment largely remains supportive. Current vector control strategies to prevent and reduce dengue transmission are neither efficient nor sustainable as long-term interventions. Increased globalization and climate change have been reported to influence dengue transmission. In this article, we reviewed the non-climatic and climatic risk factors which facilitate dengue transmission. Sustainable and effective interventions to reduce the increasing threat from dengue would require the integration of these risk factors into current and future prevention strategies, including dengue vaccination, as well as the continuous support and commitment from the political and environmental stakeholders.
authors: Communicable Disease Center, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, IIDE, 11 Jalan Tan Tock Seng, Singapore 308433, Singapore.
authors: Pang
authors: P
authors: Junxiong
authors: Leo
authors: L
authors: Yee-Sin
mesh_terms: D000330:Aedes / Q000469:parasitology*; D000818:Animals; D057231:Climate Change; D016000:Cluster Analysis; D003715:Dengue / Q000517:prevention & control / Q000635:transmission*; D004196:Disease Outbreaks; D006801:Humans; D032521:Immunity, Herd; D007303:Insect Vectors / Q000469:parasitology*; D038622:Internationality; D012307:Risk Factors; D065288:Serogroup; D013696:Temperature
keywords: climate; clustering; contacts; dengue; global warming; globalization; herd immunity; rainfall; risk factors; temperature