title: A comparitive study to evaluate the role of serum lipid levels in aetiology of carcinoma breast.
abstract: BACKGROUND
  Breast cancer is the most common occurring cancer in women worldwide. Various factors that have lead to change in lifestyle are thought to be associated with increase in breast cancer incidence in Asian countries. Several clinical studies suggest the prognostic significance of serum lipid levels in breast cancer. Present study was planned to confirm the association of lipids levels with breast cancer.
  
  
  METHODS
  Lipid analyses was carried out on serum samples from 100 breast cancer patients and 100 control women, with a age group of 25 y and above. The case & control group included 50 premenopausal women and 50 postmenopausal women.
  
  
  RESULTS
  Patients of study group had high Low density lipoproteins (LDL) (p-value - 0.00), Triglycerides (TG) (p-value -0.001) and Total cholesterol (TC) (p-value -0.00) as compared to control group. There was no association of VLDL (p-value -0.436) and HDL (p-value -0.797) among study group and control group. There was no association of lipid levels in different grades of carcinoma.
  
  
  CONCLUSIONS
  High levels of LDL, TG and TC were associated with breast cancer. However, no association was there in different grades of carcinoma. So it may be concluded that, LDL, TG and TC may be having some role in aetiology of breast cancer. Therefore, early detection and control of these factors may help in reducing the incidence of breast cancer and ultimately social and economic burden on society.
authors: Senior Resident, Department of Surgery, Guru Gobind Singh Medical College & Hospital , Faridkot, Punjab, India .
authors: Vipan
authors: V
authors: Kumar
authors: Assistant Professor, Department of Surgery, Guru Gobind Singh Medical College & Hospital , Faridkot, Punjab, India .
authors: Amandeep
authors: A
authors: Singh
authors: Professor & Head, Department of Surgery, Guru Gobind Singh Medical College & Hospital , Faridkot, Punjab, India .
authors: D S
authors: DS
authors: Sidhu
authors: Professor & Head, Department of Biochemistry, Guru Gobind Singh Medical College & Hospital , Faridkot, Punjab, India .
authors: K M D S
authors: KM
authors: Panag
keywords: Breast cancer; Lipid level; Post menopausal; Premenopausal