title: Graphene-based protein biomarker detection.
abstract: An ability to detect and quantify protein molecules, harbingers of specific pathologies, potentially underpins both early disease diagnosis and an assessment of treatment efficacy. However, the specific detection of a particular protein biomarker in a complex environment is by no means an easy task and requires a progressive improvement in sensor technology. The high surface area, volume, electrical conductance, atomic level thickness and apparent biocompatibility of graphene makes it potentially an exceedingly powerful transducer of biorecognition events; the demands of its application in biosensing, and progress to date are reviewed herein.
authors: Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK.
authors: Amol V
authors: AV
authors: Patil
authors: Flavio B
authors: FB
authors: Fernandes
authors: Paulo R
authors: PR
authors: Bueno
authors: Jason J
authors: JJ
authors: Davis
mesh_terms: D015415:Biomarkers / Q000032:analysis / Q000737:chemistry; D015374:Biosensing Techniques; D004563:Electrochemistry; D006108:Graphite / Q000737:chemistry; D011506:Proteins / Q000032:analysis* / Q000737:chemistry; D014173:Transistors, Electronic
chemical_list: D015415:Biomarkers; D011506:Proteins; D006108:Graphite