title: Chordoma and chondrosarcoma.
abstract: Chordoma and chondrosarcoma represent 2 fundamentally different and challenging central skull base pathologies. Both are largely surgical diseases with varying outcomes based on completeness of resection. Adjuvant therapy is controversial, although radiation therapy is commonly employed postoperatively, and stereotactic radiosurgery is used either in primary management or treatment of local progression.
authors: Departments of Neurosurgery and Otolaryngology, Mayo Clinic, 200 First Street, Southwest, Rochester, MN 55905, USA. Electronic address: vangompel.jamie@mayo.edu.
authors: Jamie J
authors: JJ
authors: Van Gompel
authors: Division of Otolaryngology Head and Neck Surgery, Department of Otolaryngology, Mayo Clinic, Rochester, MN 55905, USA.
authors: Jeffrey R
authors: JR
authors: Janus
mesh_terms: D002813:Chondrosarcoma / Q000601:surgery*; D002817:Chordoma / Q000601:surgery*; D003131:Combined Modality Therapy; D018450:Disease Progression; D004358:Drug Therapy / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging; D016634:Radiosurgery / Q000379:methods*; D019292:Skull Base Neoplasms / Q000601:surgery*
keywords: Chondrosarcoma; Chordoma; Outcome; Proton beam; Surgery