title: Survival trends in metastatic bladder cancer in the United States: a population based study.
abstract: BACKGROUND
  To evaluate the relative survival rates for patients with metastatic bladder cancer (MBC) over the last two decades in the United States: 1991-2000 and 2001-2010.
  
  
  METHODS
  We used the Surveillance, Epidemiology, and End Results (SEER*Stat) Program to analyze 6-month and 12-month relative survival rates of American Joint Committee on Cancer (AJCC) Stage IV bladder cancer patients included in the SEER database. We used Z-test in the SEER*Stat Program to compare relative survival rates among cohorts of patients categorized by race, gender, and age groups (<60 and ≥ 60 years).
  
  
  RESULTS
  The dataset comprised 4195 and 7629 patients with AJCC Stage IV bladder cancer in the periods 1991-2000 and 2001-2010, respectively. There were statistically significant decreases in relative survival rates for pooled data across all races (67.8 ± 0.7% in 1991-2000 vs. 64.7 ± 0.5% in 2001-2010, P < 0.01), among Caucasian (CC) and other races (Oth) men + women, among CC and Oth men, and several cohorts among men and 60 + Oth-women when categorized by age. African American patients did not show significant changes in survival.
  
  
  CONCLUSIONS
  This population-based study shows that decreases in 6-month and 12-month relative survival rates among patients with MBC in 2001-2010 compared to 1991-2000, specifically, more pronounced among CC men and Oth men.
authors: Cancer Center and Blood Institute, St. Joseph Regional Medical Center, Lewiston, ID, USA.
authors: Binay Kumar
authors: BK
authors: Shah
authors: Rakesh
authors: R
authors: Mandal
mesh_terms: D000328:Adult; D000368:Aged; D005006:Ethnicity; D005260:Female; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011159:Population Surveillance; D018426:SEER Program; D015996:Survival Rate; D014481:United States / Q000453:epidemiology / Q000208:ethnology; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology / Q000266:history / Q000401:mortality* / Q000473:pathology*