title: A Systematic Review and Meta-analysis of Endovascular Popliteal Aneurysm Repair Using the Hemobahn/Viabahn Stent-Graft.
abstract: OBJECTIVE
  To perform an evidence synthesis study to assess outcomes of endovascular repair of popliteal artery aneurysms (PAAs) using the Hemobahn or Viabahn stent-graft.
  
  
  METHODS
  A systematic literature review was conducted conforming to established standards to identify articles published between 1996 (the date of introduction of the Hemobahn stent-graft) and 2013 reporting stent-graft repair of PAAs in at least 10 patients. The data were pooled for Kaplan-Meier analysis of primary and secondary patency rates [presented with 95% confidence intervals (CIs)] as the primary outcomes. Random effects meta-analysis was performed for secondary outcomes that included rates of reintervention, endoleak, stent-graft fracture, and limb salvage.
  
  
  RESULTS
  Fourteen studies reported outcomes for 514 PAAs. There was considerable heterogeneity in reporting standards among studies. Pooled primary and secondary patency rates were 69.4% (95% CI 63.3% to 76.2%) and 77.4% (95% CI 70.1% to 85.3%), respectively, at 5 years. Five studies (including only one randomized controlled trial) compared surgical to endovascular repair; no difference was found in primary patency on evidence synthesis (hazard ratio 1.30, 95% CI 0.79 to 12.14, p=0.189).
  
  
  CONCLUSIONS
  Stent-graft repair provides a feasible treatment option for anatomically suitable PAAs. Further studies are required to optimize both patient selection and follow-up protocols.
authors: Department of Outcomes Research, St George's Vascular Institute, London, UK.
authors: Shaneel R
authors: SR
authors: Patel
authors: Department of Outcomes Research, St George's Vascular Institute, London, UK.
authors: Cían O
authors: CO
authors: Hughes
authors: Department of Outcomes Research, St George's Vascular Institute, London, UK.
authors: Keith G
authors: KG
authors: Jones
authors: Department of Outcomes Research, St George's Vascular Institute, London, UK pholt@sgul.ac.uk.
authors: Peter J E
authors: PJ
authors: Holt
authors: Department of Outcomes Research, St George's Vascular Institute, London, UK.
authors: Matt M
authors: MM
authors: Thompson
authors: Department of Outcomes Research, St George's Vascular Institute, London, UK.
authors: Robert J
authors: RJ
authors: Hinchliffe
authors: Department of Outcomes Research, St George's Vascular Institute, London, UK.
authors: Alan
authors: A
authors: Karthikesalingam
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000783:Aneurysm / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation*; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D023821:Limb Salvage; D008297:Male; D011150:Popliteal Artery / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology; D011474:Prosthesis Design; D012307:Risk Factors; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome; D014654:Vascular Patency
keywords: aneurysm; covered stent; endoleak; endovascular repair; limb salvage; meta-analysis; patency; popliteal artery; reintervention; stent fracture; stent-graft