title: Proposal of success criteria for strabismus surgery in patients with Graves' orbitopathy based on a systematic literature review.
abstract: Proposal of success criteria for strabismus surgery for patients with Graves' orbitopathy (GO) based on a systematic review of the literature. We performed a systematic search of OVID MEDLINE, OVID Embase, the Cochrane Central Register of Controlled Trials (CENTRAL) and the publisher subset of PubMed, to identify studies reporting on success criteria of strabismus surgery in GO. In addition, we handsearched several orthoptic journals and proceedings of strabismological congresses. Of the 789 articles retrieved, 42 articles described success criteria for strabismus surgery in GO. Most studies defined success in terms of a subjective diplopia-free field in primary and down gaze. Almost half of the studies used a graded scale (excellent, good, acceptable and failure) to describe the outcome of surgery. Three of the eligible studies described a tool to quantify the field of single vision in detail. Quality of life was not reported as an outcome measure in any of the published studies. In conclusion, success criteria for strabismus surgery in patients with GO are poorly defined and no consensus is available. The lack of standardization hampers comparative studies and thus the search for the best surgical treatment for diplopia in patients with GO. Therefore, we propose strict success criteria including a tool for quantification of remaining diplopia plus a disease-specific quality of life questionnaire (the GO-QoL).
authors: Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands.
authors: Hinke Marijke
authors: HM
authors: Jellema
authors: Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands.
authors: Yvette
authors: Y
authors: Braaksma-Besselink
authors: Medical Library, Academic Medical Center, Amsterdam, The Netherlands.
authors: Jacqueline
authors: J
authors: Limpens
authors: ADMEDICO Augenzentrum, Interdisziplinäres Zentrum für Endokrine Orbitopathie, Olten, Switzerland.
authors: Georg
authors: G
authors: von Arx
authors: Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands.
authors: Wilmar M
authors: WM
authors: Wiersinga
authors: Department of Ophthalmology, Academic Medical Center, Amsterdam, The Netherlands.
authors: Maarten P
authors: MP
authors: Mourits
mesh_terms: D049970:Graves Ophthalmopathy / Q000150:complications*; D006801:Humans; D009801:Oculomotor Muscles / Q000601:surgery*; D013508:Ophthalmologic Surgical Procedures / Q000592:standards*; D011785:Quality Assurance, Health Care / Q000592:standards; D011788:Quality of Life; D018434:Sickness Impact Profile; D013285:Strabismus / Q000601:surgery*; D011795:Surveys and Questionnaires
keywords: Graves' orbitopathy; quality of life; strabismus surgery; success criteria