title: "Lytic" lesions in autologous bone grafts: demonstration of medullary air pockets on post mortem computed tomography.
abstract: Donor bone grafts are an important aspect of orthopaedic surgery. The use of plain film as a pathological screening tool before donor bone dispatch has revealed "lytic" lesions in proximal humeri. Donor demographics did not support the diagnosis of myeloma and subsequent computed tomography (CT) scans of these bones identified the lesions as air, not pathology. In total, 27 long bones were scanned and 100% (27/27 cases) exhibited air within the trabecular bone. Three distinct patterns were found: ovoid, linear/branching, and broad channel. A longitudinal course of CT scans was performed to identify at which stage air appeared within the bone. Pre-retrieval, preprocessing, and postprocessing scans revealed that air originated between the retrieval and preprocessing stages of donor bone preparation. There may be multiple aetiology of this phenomenon, including bone retrieval and natural decomposition.
authors: University of Melbourne, Melbourne, Australia, a.rotman@ugrad.unimelb.edu.au.
authors: A
authors: A
authors: Rotman
authors: K
authors: K
authors: Hamilton
authors: C
authors: C
authors: O'Donnell
mesh_terms: D000388:Air; D064591:Allografts / Q000000981:diagnostic imaging* / Q000637:transplantation; D001344:Autopsy; D001853:Bone Marrow / Q000000981:diagnostic imaging; D016025:Bone Transplantation / Q000379:methods*; D005269:Femur / Q000000981:diagnostic imaging* / Q000637:transplantation; D006801:Humans; D006811:Humerus / Q000000981:diagnostic imaging* / Q000637:transplantation; D061330:Multidetector Computed Tomography; D011180:Postmortem Changes; D011237:Predictive Value of Tests; D013048:Specimen Handling; D013977:Tibia / Q000000981:diagnostic imaging* / Q000637:transplantation; D014015:Tissue Banks; D014019:Tissue Donors; D020858:Tissue and Organ Harvesting