title: Personalized and precision orthodontic therapy.
abstract: OBJECTIVE
  To bring together orthodontic stakeholders from academics, industry, and private practice for a series of thematically focused workshops to explore and develop the transfer of novel approaches into clinical orthodontic practice.
  
  
  METHODS
  Twenty-seven invited speakers, eight poster presenters, and participants of the Consortium for Orthodontic Advances in Science and Technology (COAST) 2014 Innovators' Workshop at the Eaglewood Resort and Spa, Itasca, Illinois, September 11-14, 2014.
  
  
  METHODS
  Five themed sessions involving between 4-7 presentations followed by panel discussions were organized. The aims of the discussion sessions were to highlight important findings and consider the strength of evidence for these, indicate next steps and needed research or technological developments to move forward, and to weigh the expected benefits from these findings and steps to implement in clinical practice.
  
  
  RESULTS
  Among important areas for attention identified were need for multiscale and multispecies modeling and experimentation for interspecies translation of results; large-scale collaborative efforts within the profession to address the need for adequate sample sizes for future genetic studies of complex traits such as malocclusion; a consortium approach to improve new technologies such as intra-oral scanning and 3D imaging by establishing standards; and harnessing the growing body of knowledge about bone biology for application in orthodontics.
  
  
  CONCLUSIONS
  With increased awareness of the potential of current and emerging technologies, translation of personalized and precision approaches in the field of orthodontics holds ever-increasing promise.
authors: School of Dentistry, Departments of Orthodontics & Dentofacial Orthopedics and Oral & Craniofacial Sciences, University of Missouri-Kansas City, Kansas City, MO, USA.
authors: L R
authors: LR
authors: Iwasaki
authors: D A
authors: DA
authors: Covell
authors: S A
authors: SA
authors: Frazier-Bowers
authors: S
authors: S
authors: Kapila
authors: S S
authors: SS
authors: Huja
authors: J C
authors: JC
authors: Nickel
mesh_terms: D001696:Biomechanical Phenomena; D003198:Computer Simulation; D003226:Congresses as Topic; D018865:Dental Research; D003952:Diagnostic Imaging; D004059:Diffusion of Innovation; D015894:Genome, Human; D006801:Humans; D009971:Orthodontics, Corrective; D057285:Precision Medicine; D018581:Technology Transfer; D013674:Technology, Dental; D023822:Tissue Engineering
keywords: 3D imaging; CBCT imaging; TMJ function; biology of tooth movement; bone bioengineering; bone modeling; computer technologies; personalized and precision orthodontic treatment