title: (111)In-octreotide SPECT-CT in head and neck paragangliomas.
abstract: Head and neck paragangliomas are rare neuroendocrine tumors expressing somatostatin receptors on their cell surface, particularly subtype 2. Due to this distinctive feature, images can be obtained in Nuclear Medicine using synthetic analogues of somatostatin, mainly octreotide, which allow selective display by planar scintigraphy, SPECT-CT or PET-CT imaging after radiolabeling with (111)In or (68)Ga. Three cases have been selected and presented from a series of patients that illustrate the utility of SPECT-CT studies with (111)In-octreotide in the diagnosis and monitoring of this type of tumor. These are characterization at initial diagnosis, staging, and detection of local recurrence or metastasis, with added value with respect to anatomical images (nuclear magnetic resonance, computed axial tomography, angiography), for example in the differentiation between functional tissue or scar in patients who had previously undergone surgery.
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España. Electronic address: caritocas541@hotmail.com.
authors: C
authors: C
authors: Castillo-Berrio
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.
authors: M
authors: M
authors: Castrillón
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.
authors: F
authors: F
authors: Zelaya
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.
authors: D
authors: D
authors: Ruíz
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.
authors: F
authors: F
authors: Loira
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.
authors: J M
authors: JM
authors: Nogueiras
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.
authors: A
authors: A
authors: López
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.
authors: R
authors: R
authors: Guitián
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.
authors: J
authors: J
authors: Outomuro
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.
authors: A
authors: A
authors: Serena
authors: Servicio de Medicina Nuclear, Hospital Meixoeiro, Vigo, Pontevedra, España.
authors: L M
authors: LM
authors: Campos
mesh_terms: D002345:Carotid Body Tumor / Q000000981:diagnostic imaging / Q000601:surgery; D002921:Cicatrix / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D043604:Glomus Tympanicum Tumor / Q000737:chemistry / Q000000981:diagnostic imaging / Q000601:surgery; D006258:Head and Neck Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D007205:Indium Radioisotopes; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D018365:Neoplasm, Residual; D015282:Octreotide / Q000031:analogs & derivatives; D010236:Paraganglioma, Extra-Adrenal / Q000737:chemistry / Q000000981:diagnostic imaging* / Q000556:secondary / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin / Q000032:analysis; D000072098:Single Photon Emission Computed Tomography Computed Tomography
chemical_list: D007205:Indium Radioisotopes; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin; C094279:indium-111-octreotide; D015282:Octreotide
keywords: (111)In-octreotide; Gammagrafía; Paraganglioma; SPECT-CT; SPECT-TC; Scintigraphy; Somatostatin; Somatostatina