title: Mutations in complement C3 from aHUS patients.
abstract: In this issue of Blood, Schramm et al demonstrate that the majority of mutations in complement C3 identified in atypical hemolytic uremic syndrome (aHUS) patients cause dysregulation in the alternative pathway of complement.
authors: AARHUS UNIVERSITY.
authors: Gregers R
authors: http://orcid.org/0000-0001-6292-3319
authors: GR
authors: Andersen
mesh_terms: D065766:Atypical Hemolytic Uremic Syndrome / Q000235:genetics* / Q000378:metabolism*; D003176:Complement C3 / Q000235:genetics* / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D060066:Protein Interaction Maps
chemical_list: D003176:Complement C3