title: The potential roles of actin in the nucleus.
abstract: Over the past few decades, actin's presence in the nucleus has been demonstrated. Actin is a key protein necessary for different nuclear processes. Although actin is well known for its functional role in dynamic behavior of the cytoskeleton, emerging studies are now highlighting new roles for actin. At the present time there is no doubt about the presence of actin in the nucleus. A number of studies have uncovered the functional involvement of actin in nuclear processes. Actin as one of the nuclear components has its own structured and functional rules, such as nuclear matrix association, chromatin remodeling, transcription by RNA polymerases I, II, III and mRNA processing. In this historical review, we attempt to provide an overview of our current understanding of the functions of actin in the nucleus.
authors: Department of Genetics at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran ; Department of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University (TMU), Tehran, Iran.
authors: Khadijeh
authors: K
authors: Falahzadeh
authors: Department of Biotechnology, College of Science, University of Tehran, Tehran, Iran.
authors: Amir
authors: A
authors: Banaei-Esfahani
authors: Department of Genetics at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran.
authors: Maryam
authors: M
authors: Shahhoseini
keywords: Actin; Chromatin Remodeling; Nuclear Matrix; Transcription