title: Clinical research of persimmon leaf extract and ginkgo biloba extract in the treatment of vertebrobasilar insufficiency.
abstract: This paper aims to compare the curative effects of persimmon leaf extract and ginkgo biloba extract in the treatment of headache and dizziness caused by vertebrobasilar insufficiency. Sixty patients were observed, who underwent therapy with persimmon leaf extract and ginkgo biloba extract based on the treatment of nimodipine and aspirin. After 30 days, 30 patients treated with persimmon leaf extract and 30 patients with ginkgo biloba extract were examined for changes in hemodynamic indexes and symptoms, such as headache and dizziness. The results showed statistically significant differences of 88.3% for the persimmon leaf extract and 73.1% for the ginkgo biloba extract, P < 0.05. Compared to the group of ginkgo biloba extract, the group of persimmon leaf extract had more apparent improvement in the whole blood viscosity, plasma viscosity, fibrinogen, hematokrit, and platelet adhesion rate, and the difference was statistically significant (P < 0.05 or P < 0.01). Based on these analyses, it can be concluded that persimmon leaf extract is better than ginkgo biloba extract in many aspects, such as cerebral circulation improvement, cerebral vascular expansion, hypercoagulable state lowering and vertebrobasilar insufficiency-induced headache and dizziness relief.
authors: Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
authors: S G
authors: SG
authors: Guo
authors: Department of Anesthesiology, Taian Central Hospital, Taian, China.
authors: S H
authors: SH
authors: Guan
authors: Department of Anesthesiology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
authors: G M
authors: GM
authors: Wang
authors: Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
authors: G Y
authors: GY
authors: Liu
authors: Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
authors: H
authors: H
authors: Sun
authors: Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.
authors: B J
authors: BJ
authors: Wang
authors: Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
authors: F
authors: F
authors: Xu
mesh_terms: D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity / Q000187:drug effects; D029788:Diospyros / Q000737:chemistry*; D004244:Dizziness / Q000188:drug therapy; D005260:Female; D020441:Ginkgo biloba / Q000737:chemistry*; D006261:Headache / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D018515:Plant Leaves / Q000737:chemistry; D016896:Treatment Outcome; D014715:Vertebrobasilar Insufficiency / Q000097:blood / Q000188:drug therapy*
chemical_list: D010936:Plant Extracts