title: [Diagnosis and therapy of particle disease in total hip arthroplasty].
abstract: Particle disease is caused by periarticular accumulation of attrition particles and the inflammatory reaction of the body's tissue. This process may result in osteolysis or soft tissue transformation which presents itself symptomless in the beginning and can proceed to aseptic implant loosening, fracture, implant breaking as a result of the inappropriate osseous support and to algetic and destructive soft tissue reactions as well. Attrition particles originate from tribological pairing, and the extent of the attrition or the particle concentration depend on different factors as there are the tribological pairing's material, the head size, the patient's level of activity, and the implant position. Attrition particles can also be found in the range of any modular connection. Particle disease and its resulting morphological alterations of the tribological pairing is one of the most frequent reasons for re-operation in hip endoprosthetics.
authors: Centrum für Muskuloskeletale Chirurgie, Klinik für Orthopädie/Klinik für Unfall- und Wiederherstellungschirurgie, Charité - Universitätsmedizin Berlin.
authors: M
authors: M
authors: Müller
authors: Centrum für Muskuloskeletale Chirurgie, Klinik für Orthopädie/Klinik für Unfall- und Wiederherstellungschirurgie, Charité - Universitätsmedizin Berlin.
authors: G
authors: G
authors: Wassilew
authors: Centrum für Muskuloskeletale Chirurgie, Klinik für Orthopädie/Klinik für Unfall- und Wiederherstellungschirurgie, Charité - Universitätsmedizin Berlin.
authors: C
authors: C
authors: Perka
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D002516:Ceramics; D005547:Foreign Bodies / Q000175:diagnosis* / Q000601:surgery*; D005549:Foreign-Body Reaction / Q000175:diagnosis* / Q000601:surgery*; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D061825:Metal-on-Metal Joint Prostheses; D010014:Osteolysis / Q000175:diagnosis / Q000601:surgery; D020959:Polyethylene; D011183:Postoperative Complications / Q000175:diagnosis* / Q000601:surgery*; D011474:Prosthesis Design; D011475:Prosthesis Failure; D017755:Prosthesis Fitting; D012086:Reoperation; D014057:Tomography, X-Ray Computed
chemical_list: D020959:Polyethylene