title: [Modern molecular approaches to diagnosis and treatment of high-grade brain gliomas].
abstract: The review analyzes the current state of the problem of diagnosis and therapy of high-grade gliomas on the basis of the most promising present-day approaches. The diagnostic and treatment perspectives of the molecular genetic analysis of glioblastoma markers located on the tumor cell surface are considered. Gene therapy and the use of dendritic cells and oncolytic viruses are considered as the most interesting approaches to therapy of high-grade gliomas.
authors: FGBU "Institut biologii gena" RAN.
authors: G V
authors: GV
authors: Pavlova
authors: Natsional'nyĭ issledovatel'skiĭ meditsinskiĭ universitet im. N.I. Pirogova Minzdrava Rossii; Gosudarstvennyĭ nauchnyĭ tsentr sotsial'noĭ i sudebnoĭ psikhiatrii im. V.P. Serbskogo Minzdrava Rossii.
authors: V P
authors: VP
authors: Baklaushev
authors: Khimicheskiĭ fakul'tet Moskovskogo gosudarstvennogo universiteta im. M.V. Lomonosova.
authors: M A
authors: MA
authors: Ivanova
authors: FGBNU "Nauchno-issledovatel'skiĭ institut neĭrokhirurgii im. akad. N.N. Burdenko".
authors: S A
authors: SA
authors: Goriaĭnov
authors: FGBNU "Rossiĭskiĭ onkologicheskiĭ nauchnyĭ tsentr im. N.N. Blokhina", Moskva.
authors: E Iu
authors: EI
authors: Rybalkina
authors: Khimicheskiĭ fakul'tet Moskovskogo gosudarstvennogo universiteta im. M.V. Lomonosova.
authors: A M
authors: AM
authors: Kopylov
authors: Natsional'nyĭ issledovatel'skiĭ meditsinskiĭ universitet im. N.I. Pirogova Minzdrava Rossii; Gosudarstvennyĭ nauchnyĭ tsentr sotsial'noĭ i sudebnoĭ psikhiatrii im. V.P. Serbskogo Minzdrava Rossii.
authors: V P
authors: VP
authors: Chekhonin
authors: FGBNU "Nauchno-issledovatel'skiĭ institut neĭrokhirurgii im. akad. N.N. Burdenko".
authors: A A
authors: AA
authors: Potapov
authors: FGBNU "Nauchno-issledovatel'skiĭ institut neĭrokhirurgii im. akad. N.N. Burdenko".
authors: A N
authors: AN
authors: Konovalov
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology / Q000628:therapy*; D005910:Glioma / Q000473:pathology / Q000628:therapy*; D006801:Humans