title: Managing skin and soft-tissue infection and nosocomial pneumonia caused by MRSA: a 2014 follow-up survey.
abstract: As a follow-up to our 2009 survey, in order to explore opinion and practice on the epidemiology and management of meticillin-resistant Staphylococcus aureus (MRSA) in Europe, we conducted a second survey to elicit current opinions on this topic, particularly around antibiotic choice, dose, duration and route of administration. We also aimed to further understand how the management of MRSA has evolved in Europe during the past 5 years. Members of an expert panel of infectious diseases specialists convened in London (UK) in January 2014 to identify and discuss key issues in the management of MRSA. Following this meeting, a survey was developed comprising 36 questions covering a wide range of topics on MRSA complicated skin and soft-tissue infection and nosocomial pneumonia management. The survey instrument, a web-based questionnaire, was sent to the International Society of Chemotherapy for distribution to registered European infection societies and their members. This article reports the survey results from the European respondents. At the time of the original survey, the epidemiology of MRSA varied significantly across Europe and there were differing views on best practice. The current findings suggest that the epidemiology of healthcare-associated MRSA in Europe is, if anything, even more polarised, whilst community-acquired MRSA has become much more common. However, there now appears to be a much greater knowledge of current treatment/management options, and antimicrobial stewardship has moved forward considerably in the 5 years since the last survey.
authors: Department of Microbiology and Communicable Diseases, Royal Hampshire County Hospital, Romsey Road, Winchester, Hampshire SO22 5DG, UK. Electronic address: matthew.dryden@hhft.nhs.uk.
authors: Matthew
authors: M
authors: Dryden
authors: Department of Clinical Microbiology, University Hospital for Infectious Diseases, Zagreb, Croatia.
authors: Arjana Tambic
authors: AT
authors: Andrasevic
authors: Santa Maria della Misericordia University Hospital, Udine, Italy.
authors: Matteo
authors: M
authors: Bassetti
authors: Division of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, University of Madrid, Madrid, Spain.
authors: Emilio
authors: E
authors: Bouza
authors: Service de Réanimation Médicale, Institut de Cardiologie, Groupe Hospitalier Pitié-Salpêtrière, Paris, France; Assistance Publique-Hôpitaux de Paris, University of Paris VI (Université Pierre et Marie Curie), Paris, France.
authors: Jean
authors: J
authors: Chastre
authors: University of Salford, University Hospital of South Manchester NHS Foundation Trust, Salford, Manchester, UK.
authors: Mo
authors: M
authors: Baguneid
authors: Department of Infectious Diseases, University of Salerno, Salerno, Italy.
authors: Silvano
authors: S
authors: Esposito
authors: 6th Department of Internal Medicine, Hygeia General Hospital, Athens, Greece.
authors: Helen
authors: H
authors: Giamarellou
authors: Department of Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands; Hasselt University, Hasselt, Belgium.
authors: Inge
authors: I
authors: Gyssens
authors: Infection Unit, Ninewells Hospital and Medical School, Dundee, UK.
authors: Dilip
authors: D
authors: Nathwani
authors: Department of Infectious Diseases, Medical Faculty, Hacettepe University, Ankara, Turkey.
authors: Serhat
authors: S
authors: Unal
authors: Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
authors: Andreas
authors: A
authors: Voss
authors: Department of Microbiology, Old Medical School, Leeds Teaching Hospitals, Leeds, UK.
authors: Mark
authors: M
authors: Wilcox
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D003428:Cross Infection / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D011307:Drug Prescriptions / Q000592:standards; D004363:Drug Utilization / Q000592:standards; D005060:Europe / Q000453:epidemiology; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D011023:Pneumonia, Staphylococcal / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D018461:Soft Tissue Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D013207:Staphylococcal Skin Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D011795:Surveys and Questionnaires
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotic management; Complicated skin and soft-tissue infection; Europe; Infection; Meticillin-resistant Staphylococcus aureus; Nosocomial pneumonia