title: ALDB: a domestic-animal long noncoding RNA database.
abstract: BACKGROUND
  Long noncoding RNAs (lncRNAs) have attracted significant attention in recent years due to their important roles in many biological processes. Domestic animals constitute a unique resource for understanding the genetic basis of phenotypic variation and are ideal models relevant to diverse areas of biomedical research. With improving sequencing technologies, numerous domestic-animal lncRNAs are now available. Thus, there is an immediate need for a database resource that can assist researchers to store, organize, analyze and visualize domestic-animal lncRNAs.
  
  
  RESULTS
  The domestic-animal lncRNA database, named ALDB, is the first comprehensive database with a focus on the domestic-animal lncRNAs. It currently archives 12,103 pig intergenic lncRNAs (lincRNAs), 8,923 chicken lincRNAs and 8,250 cow lincRNAs. In addition to the annotations of lincRNAs, it offers related data that is not available yet in existing lncRNA databases (lncRNAdb and NONCODE), such as genome-wide expression profiles and animal quantitative trait loci (QTLs) of domestic animals. Moreover, a collection of interfaces and applications, such as the Basic Local Alignment Search Tool (BLAST), the Generic Genome Browser (GBrowse) and flexible search functionalities, are available to help users effectively explore, analyze and download data related to domestic-animal lncRNAs.
  
  
  CONCLUSIONS
  ALDB enables the exploration and comparative analysis of lncRNAs in domestic animals. A user-friendly web interface, integrated information and tools make it valuable to researchers in their studies. ALDB is freely available from http://res.xaut.edu.cn/aldb/index.jsp.
authors: School of Computer Science and Technology, Xidian University, Xi'an, Shaanxi, PR China; School of Computer Science and Engineering, Xi'an University of Technology, Xi'an, Shaanxi, PR China.
authors: Aimin
authors: A
authors: Li
authors: School of Computer Science and Technology, Xidian University, Xi'an, Shaanxi, PR China.
authors: Junying
authors: J
authors: Zhang
authors: Department of Molecular and Cell Biology, School of Life Sciences, University of Science and Technology of China, Hefei, PR China; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, PR China.
authors: Zhongyin
authors: Z
authors: Zhou
authors: School of Computer Science and Engineering, Xi'an University of Technology, Xi'an, Shaanxi, PR China.
authors: Lei
authors: L
authors: Wang
authors: Xi'an DongXing Branch, CMST Development Co. Ltd., Xi'an, Shaanxi, PR China.
authors: Yujuan
authors: Y
authors: Liu
authors: School of Computer Science and Technology, Xidian University, Xi'an, Shaanxi, PR China; Higher Technology College, Xi'an University of Technology, Xi'an, Shaanxi, PR China.
authors: Yajun
authors: Y
authors: Liu
mesh_terms: D000818:Animals; D000829:Animals, Domestic; D002417:Cattle; D002645:Chickens / Q000235:genetics*; D030561:Databases, Nucleic Acid; D005260:Female; D058977:Molecular Sequence Annotation; D040641:Quantitative Trait Loci; D062085:RNA, Long Noncoding / Q000145:classification / Q000235:genetics*; D012984:Software; D013552:Swine / Q000235:genetics*
chemical_list: D062085:RNA, Long Noncoding