title: [Comparative study of clinical features between unilateral and bilateral orbital IgG4-related disease].
abstract: OBJECTIVE
  Descriptive and comparative study of patients with orbital IgG4-related disease.
  
  
  METHODS
  A review and analysis of the cases diagnosed with inflammatory orbital lesion related to IgG4 by the Ophthalmic Pathology Service in the Dr. Luis Sánchez Bulnes Hospital.
  
  
  RESULTS
  A total of 9 cases were found, in which 66% were women, and with a mean age of 48 years and time to diagnosis of 2 years. Unilateral involvement was observed in 56% of cases. All the females experienced pain, and there was an optimal response to corticosteroid treatment in 100% of patients who required medical treatment (one case showed spontaneous resolution). In bilateral cases (44%), only 25% were female, and none had pain as a presenting symptom. Furthermore, 25% of these patients required a combination with immunosuppressants to control inflammation.
  
  
  CONCLUSIONS
  Clinical presentation of patients with unilateral orbital IgG4-related disease differs from those with bilateral involvement.
authors: Servicio de Órbita, Párpados y Vía Lagrimal, Hospital Dr. Luis Sánchez Bulnes, Asociación para Evitar la Ceguera IAP, México D.F. México. Electronic address: icg_ct@yahoo.es.
authors: I
authors: I
authors: Coloma-González
authors: Servicio de Órbita, Párpados y Vía Lagrimal, Hospital Dr. Luis Sánchez Bulnes, Asociación para Evitar la Ceguera IAP, México D.F. México.
authors: A
authors: A
authors: Ceriotto
authors: Servicio de Órbita, Párpados y Vía Lagrimal, Hospital Dr. Luis Sánchez Bulnes, Asociación para Evitar la Ceguera IAP, México D.F. México.
authors: J
authors: J
authors: Flores-Preciado
authors: Servicio de Órbita, Párpados y Vía Lagrimal, Hospital Dr. Luis Sánchez Bulnes, Asociación para Evitar la Ceguera IAP, México D.F. México.
authors: S
authors: S
authors: Corredor-Casas
authors: Servicio de Órbita, Párpados y Vía Lagrimal, Hospital Dr. Luis Sánchez Bulnes, Asociación para Evitar la Ceguera IAP, México D.F. México.
authors: G
authors: G
authors: Salcedo-Casillas
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003430:Cross-Sectional Studies; D003607:Dacryocystitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D057210:Delayed Diagnosis; D058447:Eye Pain / Q000209:etiology; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007074:Immunoglobulin G / Q000032:analysis; D008297:Male; D008875:Middle Aged; D008882:Mikulicz' Disease / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D009916:Orbital Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology
chemical_list: D000305:Adrenal Cortex Hormones; D007074:Immunoglobulin G
keywords: Dacrioadenitis; Dacryoadenitis; Enfermedad asociada a IgG4; Enfermedad de Mikulicz; Enfermedad inflamatoria de la órbita; IgG4-related disease; Inflammatory orbital disease; Mikulicz's disease; Orbital tumor; Tumor orbitario