title: Gastrointestinal cryptococcoma - Immune reconstitution inflammatory syndrome or cryptococcal relapse in a patient with AIDS?
abstract: The introduction of antiretroviral therapy (ART) may lead to unusual paradoxical and unmasking presentations of opportunistic infections. Intra-abdominal cryptococcosis is a rare manifestation of Cryptococcus. We present the case of an HIV-infected patient on ART, with a history of cryptococcal meningitis who presented with subacute, worsening abdominal pain during immune recovery. This evolved into chronic abdominal pain, with thickened bowel, and abdominal lymphadenopathy, while receiving empiric tuberculosis treatment. At 6-months, he developed intestinal perforation due to a histologically confirmed cryptococcoma.
authors: Infectious Disease Institute, College of health Sciences, Makerere University, Kampala, Uganda ; Department of Medicine, School of Medicine, College of Health Sciences, Makerere University and Mulago Hospital, Kampala, Uganda.
authors: Abdu K
authors: AK
authors: Musubire
authors: Infectious Disease Institute, College of health Sciences, Makerere University, Kampala, Uganda ; Division of Infectious Diseases & International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA ; Department of Medicine, School of Medicine, College of Health Sciences, Makerere University and Mulago Hospital, Kampala, Uganda.
authors: David B
authors: DB
authors: Meya
authors: Department of Pathology, College of Health Sciences, Makerere University, Kampala, Uganda.
authors: Robert
authors: R
authors: Lukande
authors: Infectious Disease Institute, College of health Sciences, Makerere University, Kampala, Uganda ; Division of Infectious Diseases & International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
authors: Andrew
authors: A
authors: Kambugu
authors: Division of Infectious Diseases & International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
authors: Paul R
authors: PR
authors: Bohjanen
authors: Division of Infectious Diseases & International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
authors: David R
authors: DR
authors: Boulware
keywords: AIDS; Antiretroviral therapy; Cryptococcal meningitis; Cryptococcoma; HIV; Immune reconstitution inflammatory syndrome