title: Impact of umbilical cord blood-derived mesenchymal stem cells on cardiovascular research.
abstract: Over the years, cell therapy has become an exciting opportunity to treat human diseases. Early enthusiasm using adult stem cell sources has been tempered in light of preliminary benefits in patients. Considerable efforts have been dedicated, therefore, to explore alternative cells such as those extracted from umbilical cord blood (UCB). In line, UCB banking has become a popular possibility to preserve potentially life-saving cells that are usually discarded after birth, and the number of UCB banks has grown worldwide. Thus, a brief overview on the categories of UCB banks as well as the properties, challenges, and impact of UCB-derived mesenchymal stem cells (MSCs) on the area of cardiovascular research is presented. Taken together, the experience recounted here shows that UCBMSCs are envisioned as attractive therapeutic candidates against human disorders arising and/or progressing with vascular deficit.
authors: ICREC Research Program, Germans Trias i Pujol Health Science Research Institute, Can Ruti Campus, 08916 Badalona, Spain.
authors: Santiago
authors: S
authors: Roura
authors: Cell Processing Laboratory, Parc Científic i Tecnològic Universitat de Girona, 17003 Girona, Spain.
authors: Josep Maria
authors: JM
authors: Pujal
authors: ICREC Research Program, Germans Trias i Pujol Health Science Research Institute, Can Ruti Campus, 08916 Badalona, Spain.
authors: Carolina
authors: C
authors: Gálvez-Montón
authors: ICREC Research Program, Germans Trias i Pujol Health Science Research Institute, Can Ruti Campus, 08916 Badalona, Spain ; Cardiology Service, Germans Trias i Pujol University Hospital, 08916 Badalona, Spain ; Department of Medicine, UAB, Barcelona, Spain.
authors: Antoni
authors: A
authors: Bayes-Genis
mesh_terms: D002318:Cardiovascular Diseases / Q000473:pathology / Q000628:therapy*; D036101:Cord Blood Stem Cell Transplantation; D005312:Fetal Blood / Q000166:cytology* / Q000637:transplantation; D006801:Humans; D059630:Mesenchymal Stem Cells; D057905:Stem Cell Research