title: Balo's Concentric Sclerosis with Acute Presentation and Co-Existing Multiple Sclerosis-Typical Lesions on MRI.
abstract: Balo's disease also known as Balo's concentric sclerosis (BCS) is a rare demyelinating disorder which is characterized pathologically and radiologically by concentric rings of demyelinated and relatively myelin-preserved white matter. We describe the case of a 25-year-old female presenting with stroke-like symptoms who was diagnosed with BCS on MRI. At clinical onset, she also showed co-existing multiple sclerosis (MS)-typical lesions in the brain. This report extends the recent concept that BCS may share similar pathogenesis and radiological progression as MS lesions, that they may occur simultaneously in the same patient and that they may represent different manifestations of the same disease process. Also, BCS needs not be a fulminant disease and may often show a benign self-limiting course as in our case.
authors: Institute for Neuroradiology, University Hospital of Zurich, Switzerland.
authors: Bela
authors: B
authors: Purohit
authors: Institute for Neuroradiology, University Hospital of Zurich, Switzerland.
authors: Eranga
authors: E
authors: Ganewatte
authors: Department of Neurology, University Hospital of Zurich, Switzerland ; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
authors: Bettina
authors: B
authors: Schreiner
authors: Institute for Neuroradiology, University Hospital of Zurich, Switzerland.
authors: Spyros
authors: S
authors: Kollias
keywords: Atypical idiopathic inflammatory demyelinating lesions; Balo's concentric sclerosis; Multiple sclerosis