title: Functional cortical and cerebellar reorganization in a case of moyamoya disease.
abstract: BACKGROUND
  Functional studies have been previous reported in stroke patients, but no studies of functional magnetic resonance imaging have been performed in Moyamoya disease.
  
  
  OBJECTIVE
  To assess the cortical and cerebellar reorganization in a moyamoya patient.
  
  
  METHODS
  We reported a case of a patient suffering from moyamoya disease, undergoing a neuropsychological assessment, a neurocognitive rehabilitative treatment, an electroencephalogram evaluation, and a functional magnetic resonance imaging examination.
  
  
  RESULTS
  The subject showed a cognitive impairment, a slow electroencephalogram activity, and the ipsi- and controlateral motor cortex and cerebellar functional magnetic resonance imaging activation.
  
  
  CONCLUSIONS
  This is the first functional magnetic resonance imaging case study reported in moyamoya disease. We showed a cortical reorganization, which could play an important role in clinical evaluation and motor recovery. The cerebellar activation, showed after cognitive and motor rehabilitation, could support the idea that the cerebellum contains several cognitive-related subregions involved in different functional networks in moyamoya disease.
authors: All from IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
authors: Rocco S
authors: RS
authors: Calabrò
authors: All from IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
authors: Placido
authors: P
authors: Bramanti
authors: All from IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
authors: Annalisa
authors: A
authors: Baglieri
authors: All from IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
authors: Francesco
authors: F
authors: Corallo
authors: All from IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
authors: Rosaria
authors: R
authors: De Luca
authors: All from IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
authors: Simona
authors: S
authors: De Salvo
authors: All from IRCCS Centro Neurolesi Bonino-Pulejo, Messina, Italy.
authors: Silvia
authors: S
authors: Marino
keywords: Cerebellar reorganization; cortical reorganization; fMRI; functional magnetic resonance imaging; moyamoya disease; rehabilitation