title: [The mode of differential diagnostic of and acute alcoholic gastroenteritis].
abstract: The study was carried out to develop mode of differential diagnostic of salmonella and acute alcoholic gastroenteritis on the basis of phospholipid specter of blood serum. The indicators of phospholipid fractions of blood serum were analyzed in 50 healthy persons, 50 patients with acute alcoholic gastroenteritis and 50 patients with salmonella gastroenteritis were analyzed. The relative content of following fractions of whole phospholipids were analyzed--total lysophospholipids, sphyngomiyelin, phosphatidcholine, phosphatidyletanolamin. The phospholipid spectrum of blood serum can be applied in differential diagnostic of salmonella gastroenteritis and acute alcoholic gastroenteritis. The disorders of metabolism of lipids under given pathological conditions have a multidirectional character. The salmonella gastroenteritis is characterized by decreasing of relative content of total lysophospholipids and increasing of phosphatidcholine as compared with standard conditions. The acute alcoholic gastroenteritis is characterized by increasing of relative content of total lysophospholipids and phosphatidcholine and decreasing of level of phosphatidcholine. The content of total Iysophospholipids in blood serum is lower on 35% or 30.0 mg% permits diagnosing acute alcoholic gastroenteritis. The content of phosphaltidcholine in blood serum higher than 40% or 50 mg% permits diagnosing salmonella gastroenteritis.
authors: V K
authors: VK
authors: Makarov
authors: P V
authors: PV
authors: Makarov
mesh_terms: D000328:Adult; D000438:Alcohols / Q000633:toxicity; D001688:Biological Products / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D005759:Gastroenteritis / Q000097:blood* / Q000139:chemically induced / Q000382:microbiology; D006801:Humans; D008246:Lysophospholipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000097:blood; D012475:Salmonella / Q000235:genetics / Q000472:pathogenicity; D012480:Salmonella Infections / Q000097:blood* / Q000382:microbiology
chemical_list: D000438:Alcohols; D001688:Biological Products; D008246:Lysophospholipids; D010743:Phospholipids; C068291:poractant alfa; C032881:lysophosphatidic acid