title: Superior vena cava syndrome as an initial presentation of low-grade follicular lymphoma.
abstract: Superior vena cava (SVC) syndrome refers to a constellation of symptoms produced by the obstruction of blood flow through the SVC, resulting in symptoms of dyspnea, facial and upper-extremity edema, cough, chest pain, and dysphagia.1 Malignancies represent 60%-85% of the etiologies of SVC syndrome. Cumulatively, lymphoma and lung cancer represent 95% of malignancy-related SVC syndrome etiologies, with non-small-cell lung cancer (NSCLC) reported in about 50% of cases, small-cell lung cancer (SCLC) in about 25%, and non-Hodgkin lymphoma (NHL) in 10 % of all cases.
authors: Department of Internal Medicine, Pennsylvania Hospital, Philadelphia, Pennsylvania, USA. shakirajgrant@gmail.com.
authors: Shakira
authors: S
authors: Grant
authors: Department of Pathology, Pennsylvania Hospital, Philadelphia, Pennsylvania, USA.
authors: Simon
authors: S
authors: Meykler
authors: Abramson Cancer Center, Pennsylvania Hospital, Philadelphia, Pennsylvania, USA.
authors: Doublas
authors: D
authors: Beach
keywords: Non Hodgkin's Lymphoma; SVC syndrome; follicular; indolent lymphoma