title: Successful treatment of Cryptococcus laurentii peritonitis in a patient on peritoneal dialysis.
abstract: A 32-year-old man on peritoneal dialysis (PD) was hospitalized for seven days due to fever. A diagnosis of yeast-like fungal peritonitis was made by Gram staining. The patient was started on intravenous micafungin and oral fluconazole therapy following removal of the PD catheter. A fungal pathogen was isolated from the peritoneal fluid and identified as Cryptococcus species. Based on antifungal susceptibility testing, the treatment was changed to voriconazole and continued for 3 months. A genetic analysis identified the isolate as Cryptococcus laurentii (C. laurentii). This patient was diagnosed with C. laurentii PD-related peritonitis and was successfully treated with voriconazole and removal of the PD catheter.
authors: Department of Nephrology, Handa Municipal Hospital, Japan.
authors: Marina
authors: M
authors: Asano
authors: Makoto
authors: M
authors: Mizutani
authors: Yasuko
authors: Y
authors: Nagahara
authors: Koji
authors: K
authors: Inagaki
authors: Tetsuyoshi
authors: T
authors: Kariya
authors: Daijiro
authors: D
authors: Masamoto
authors: Makoto
authors: M
authors: Urai
authors: Yukihiro
authors: Y
authors: Kaneko
authors: Hideaki
authors: H
authors: Ohno
authors: Yoshitsugu
authors: Y
authors: Miyazaki
authors: Masashi
authors: M
authors: Mizuno
authors: Yasuhiko
authors: Y
authors: Ito
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage*; D002404:Catheterization; D002408:Catheters, Indwelling / Q000009:adverse effects / Q000382:microbiology; D003454:Cryptococcus / Q000302:isolation & purification*; D020878:Device Removal; D054714:Echinocandins / Q000008:administration & dosage*; D015725:Fluconazole / Q000008:administration & dosage*; D006801:Humans; D055666:Lipopeptides / Q000008:administration & dosage*; D008297:Male; D000077551:Micafungin; D009181:Mycoses / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010538:Peritonitis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D015725:Fluconazole; D000077551:Micafungin