title: Apple or pear: size and shape matter.
abstract: Obesity-related morbidity and mortality are related to fat accumulation and fat distribution in humans. Two large-scale meta-analyses recently published in Nature by Shungin et al. (2015) and Locke et al. (2015) report novel genetic associations for central and overall obesity; these greatly advance our understanding of the biology of obesity.
authors: Molecular Genetics Section, Department of Pediatrics, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands; Department of Genetics, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands. Electronic address: fjingyuan@gmail.com.
authors: Jingyuan
authors: J
authors: Fu
authors: Molecular Genetics Section, Department of Pediatrics, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands.
authors: Marten
authors: M
authors: Hofker
authors: Department of Genetics, University of Groningen, University Medical Center Groningen, 9712 CP Groningen, The Netherlands.
authors: Cisca
authors: C
authors: Wijmenga
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D050218:Body Fat Distribution; D015992:Body Mass Index; D005260:Female; D055106:Genome-Wide Association Study; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D008297:Male; D009765:Obesity / Q000235:genetics* / Q000378:metabolism*; D040641:Quantitative Trait Loci / Q000235:genetics*
chemical_list: D007328:Insulin