title: Release of cardiac troponin using a high sensitivity assay after exercise: Type 2 acute myocardial infarction?
abstract: BACKGROUND
  Cardiac troponin is used as a marker for all types of myocardial infarction.
  
  
  METHODS
  Assays for high-sensitivity troponin T and I were performed before, immediately and 24h after a 40 km bicycle ride in two middle aged individuals.
  
  
  RESULTS
  There was a significant increase in cardiac troponin immediately after exercise in both individuals. This was accompanied by a return to baseline levels within 24h. A CT angiogram was normal in one while the other had a significant occlusion in the mid-right coronary artery. After a stent placement, in this latter individual, there was no major increase in troponin after a second bicycle ride.
  
  
  CONCLUSIONS
  Using high sensitivity assays, at least one of these two subjects may have suffered a type 2 myocardial infarction had the increases in hs-cTnI were accompanied by other acceptable evidence of myocardial ischemia (symptoms, ECG, etc.).
authors: Changi General Hospital, Singapore.
authors: Tar Choon
authors: TC
authors: Aw
authors: University of California, San Diego, United States.
authors: Xander M R
authors: XM
authors: van Wijk
authors: University of California, San Francisco, United States. Electronic address: wualan@labmed2.ucsf.edu.
authors: Alan H B
authors: AH
authors: Wu
authors: The Mayo Clinic, Rochester, MN, United States.
authors: Allan S
authors: AS
authors: Jaffe
mesh_terms: D015415:Biomarkers / Q000097:blood; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000000981:diagnostic imaging*; D011859:Radiography; D019210:Troponin I / Q000097:blood*; D020107:Troponin T / Q000097:blood*
chemical_list: D015415:Biomarkers; D019210:Troponin I; D020107:Troponin T
keywords: CT angiogram; Cardiac troponin; High sensitivity; Type 2 myocardial infarction