title: Amino acid uptake in erythropoiesis.
abstract: Erythroblasts produce huge amounts of hemoglobin, for which they must incorporate vast stores of iron and amino acids. In the 14 April issue of Science Signaling, Chung et al. describe the complex mechanism linking neutral amino acid uptake to hemoglobin production in these hungry cells.
authors: Dana-Farber Cancer Institute, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. david_nathan@dfci.harvard.edu.
authors: David G
authors: DG
authors: Nathan
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D039642:Eukaryotic Initiation Factors / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D007930:Leucine / Q000378:metabolism*; D046912:Multiprotein Complexes / Q000378:metabolism*; D010750:Phosphoproteins / Q000378:metabolism*; D058570:TOR Serine-Threonine Kinases / Q000378:metabolism*
chemical_list: D002352:Carrier Proteins; D039642:Eukaryotic Initiation Factors; D006454:Hemoglobins; D046912:Multiprotein Complexes; D010750:Phosphoproteins; D058570:TOR Serine-Threonine Kinases; D007930:Leucine