title: Cardiac fibroblasts form and function.
abstract: The formation and structure of the extracellular matrix (ECM) that makes up the cardiac interstitum is well known yet the underlying mechanisms that regulate the interstitum are poorly known. This review focuses on the role of the cardiac fibroblast in the formation and regulation of the ECM components during cardiac development and in response to physiological and pathological stimulation. The role of ECM receptors (integrins), cellular phenotype, and chemical and mechanical signaling by cardiac fibroblasts are discussed.
authors: Department of Developmental Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina USA.
authors: S
authors: S
authors: Kanekar
authors: Department of Developmental Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina USA.
authors: T
authors: T
authors: Hirozanne
authors: Department of Developmental Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina USA.
authors: L
authors: L
authors: Terracio
authors: Department of Developmental Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina USA.
authors: T K
authors: TK
authors: Borg