title: Anti-neutrophil cytoplasmic antibody-associated vasculitis associated with infectious mononucleosis due to primary Epstein-Barr virus infection: report of three cases.
abstract: Although the aetiology of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis remains unclear, it is generally believed that environmental factors such as infections contribute to its development of ANCA-associated vasculitis. Prior Epstein-Barr virus (EBV) infection is reported to be a trigger of systemic vasculitis. We herein report three cases of ANCA-associated vasculitis presenting with infectious mononucleosis due to primary EBV infection. The causal link between the two pathologies could not be proved, but primary EBV infection may play a role in the initiation or exacerbation of ANCA-associated vasculitis. Future studies are necessary to determine the interaction between these diseases conditions.
authors: Department of Nephrology , Toyohashi Municipal Hospital , Toyohashi , Japan.
authors: Makoto
authors: M
authors: Yamaguchi
authors: Department of Nephrology , Toyohashi Municipal Hospital , Toyohashi , Japan.
authors: Tomoki
authors: T
authors: Yoshioka
authors: Department of Nephrology , Toyohashi Municipal Hospital , Toyohashi , Japan.
authors: Taishi
authors: T
authors: Yamakawa
authors: Department of Pathology , Toyohashi Municipal Hospital , Toyohashi , Japan.
authors: Matsuyoshi
authors: M
authors: Maeda
authors: Department of Nephrology , Chubu Rosai Hospital , Nagoya , Japan.
authors: Hideaki
authors: H
authors: Shimizu
authors: Department of Nephrology , Chubu Rosai Hospital , Nagoya , Japan.
authors: Yoshiro
authors: Y
authors: Fujita
authors: Department of Nephrology and Renal Replacement Therapy , Nagoya University Graduate School of Medicine , Nagoya , Japan.
authors: Shoichi
authors: S
authors: Maruyama
authors: Department of Nephrology and Renal Replacement Therapy , Nagoya University Graduate School of Medicine , Nagoya , Japan.
authors: Yasuhiko
authors: Y
authors: Ito
authors: Department of Nephrology and Renal Replacement Therapy , Nagoya University Graduate School of Medicine , Nagoya , Japan.
authors: Seiichi
authors: S
authors: Matsuo
keywords: Epstein–Barr virus; anti-neutrophil cytoplasmic antibody; infectious mononucleosis; vasculitis