title: Prospects of stem cell treatment in benign urological diseases.
abstract: Stem cells (SCs) are undifferentiated cells that are capable of self-renewal and differentiation and that therefore contribute to the renewal and repair of tissues. Their capacity for division, differentiation, and tissue regeneration is highly dependent on the surrounding environment. Several preclinical and clinical studies have utilized SCs in urological disorders. In this article, we review the current status of SC use in benign urological diseases (erectile dysfunction, Peyronie disease, infertility, and urinary incontinence), and we summarize the results of the preclinical and clinical trials that have been conducted.
authors: Department of Urology, University of California, San Francisco, CA, USA. ; Department of Urology, King Abdul Aziz University, Jeddah, Saudi Arabia.
authors: Amjad
authors: A
authors: Alwaal
authors: Department of Urology, University of California, San Francisco, CA, USA. ; Department of Urology, Cairo University, Cairo, Egypt.
authors: Ahmed A
authors: AA
authors: Hussein
authors: Department of Urology, University of California, San Francisco, CA, USA.
authors: Ching-Shwun
authors: CS
authors: Lin
authors: Department of Urology, University of California, San Francisco, CA, USA.
authors: Tom F
authors: TF
authors: Lue
mesh_terms: D007172:Erectile Dysfunction / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D033581:Stem Cell Transplantation / Q000379:methods*; D014549:Urinary Incontinence / Q000503:physiopathology / Q000628:therapy*
keywords: Erectile dysfunction; Infertility; Stem cells; Urinary incontinence