title: [Meta-analysis of the relationship between particulate matter (PM(10) and PM(2.5)) and asthma hospital admissions in children].
abstract: OBJECTIVE
  To systematically review and assess the relationship between particulate matter (PM(10) and PM(2.5)) and children's hospital admissions for asthma, using both time-series and case-crossover analyses.
  
  
  METHODS
  The PubMed, Ebsco, Ovid and four Chinese periodical databases were screened for studies related to short-term effects of particulate matter on pediatric asthma hospital admissions published from 1 January 1990 to 31 December 2013.Sixteen studies on PM(10) and 10 studies on PM(2.5) were selected finally for meta-analysis. Relative risk (RR) or odds ratio (OR) and 95% confidence intervals (CI) of asthma hospital admissions per 10 µg/m³ increase of daily particulate matter were obtained from each study. RevMan 5.2.11 was used to test the heterogeneity of the results among the different studies and amalgamat the effect size by fixed or random effect model.
  
  
  RESULTS
  As the concentration of PM(10) increased per 10 µg/m³, the children's hospital admissions for asthma increased by 1.75%; for PM(2.5), a 3.45% increase for asthma hospital admissions as the concentration increased per 10 µg/m³. By subgroup analysis based on study design, the effect size on both PM(10) and PM(2.5) of case-crossover study's results were higher than time-series analysis.
  
  
  CONCLUSIONS
  The short-term increase of the concentration of PM(10) and PM(2.5) may led to the increase of Children's hospital admissions for asthma, and PM(2.5) will present a higher risk contribution.
authors: Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
authors: Ling
authors: L
authors: Ding
authors: Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
authors: Daojuan
authors: D
authors: Zhu
authors: Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. Email: pdhdxy@163.com.
authors: Donghong
authors: D
authors: Peng
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects*; D001249:Asthma / Q000453:epidemiology*; D002648:Child; D002681:China / Q000453:epidemiology; D018592:Cross-Over Studies; D006760:Hospitalization / Q000706:statistics & numerical data*; D006776:Hospitals, Pediatric; D006801:Humans; D016017:Odds Ratio; D052638:Particulate Matter
chemical_list: D000393:Air Pollutants; D052638:Particulate Matter