title: Silver nanopartical over AuFON substrate for enhanced raman readout and their application in pesticide monitoring.
abstract: Surface-enhanced Raman detection of thiram is demonstrated by using Ag-nanoparticles (Ag NPs) on Au film over nanosphere (AuFON) substrate as the hybrid substrate. The SERS signal of the Ag NPs attached to solid supports is studied. The close coupling together of thousands of Ag NPs on AuFON leads to the generation of hot spots for SERS. The Ag NPs on AuFON can be applied to detect rhodamine-6G (R6G) with the detection limitation of 10-11 M and the pesticide thiram in acetone with a detection limit of as low as 0.24 ppm, which is much lower than the maximal residue limit (MRL) of 7 ppm in fruit prescribed by the U.S. Environmental Protection Agency (EPA). The hybrid substrates are shown to be highly sensitive for the detection of thriam, which produce highly enhanced Raman signals with good uniformity and reproducibility due to having plenty of hot spots on its surface.
authors: Beijing Key Laboratory of New Molecular Diagnosis Technologies for Infectious Diseases, Beijing Institute of Radiation Medicine, Beijing 100850, China. momokunlun@foxmail.com.|Department of Occupational and Environmental Health, School of Public Health, Jilin University, Changchun 130021, China. momokunlun@foxmail.com.
authors: Kun
authors: K
authors: Guo
authors: Beijing Key Laboratory of New Molecular Diagnosis Technologies for Infectious Diseases, Beijing Institute of Radiation Medicine, Beijing 100850, China. ruix203@sina.com.
authors: Rui
authors: R
authors: Xiao
authors: School of Pharmaceutical Sciences, Jilin University, Changchun 130021, China. zxyxiaoye@163.com.
authors: Xiaoye
authors: X
authors: Zhang
authors: College of Mechatronics Engineering and Automation, National University of Defense Technology, Changsha 410073, China. cg.king@163.com.
authors: Chaoguang
authors: C
authors: Wang
authors: Beijing Key Laboratory of New Molecular Diagnosis Technologies for Infectious Diseases, Beijing Institute of Radiation Medicine, Beijing 100850, China. liuqiqi@bmi.ac.cn.
authors: Qiqi
authors: Q
authors: Liu
authors: Beijing Key Laboratory of New Molecular Diagnosis Technologies for Infectious Diseases, Beijing Institute of Radiation Medicine, Beijing 100850, China. rongzhen0525@sina.com.
authors: Zhen
authors: Z
authors: Rong
authors: Department of Occupational and Environmental Health, School of Public Health, Jilin University, Changchun 130021, China. jlyelin@163.com.
authors: Lin
authors: L
authors: Ye
authors: Beijing Key Laboratory of New Molecular Diagnosis Technologies for Infectious Diseases, Beijing Institute of Radiation Medicine, Beijing 100850, China. doudoucsh@sina.com.
authors: Suhong
authors: S
authors: Chen
mesh_terms: D003247:Conservation of Natural Resources; D006046:Gold / Q000737:chemistry; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D054118:Nanospheres / Q000737:chemistry; D010575:Pesticides / Q000737:chemistry / Q000302:isolation & purification*; D012235:Rhodamines / Q000302:isolation & purification* / Q000633:toxicity; D012834:Silver / Q000737:chemistry*; D013059:Spectrum Analysis, Raman; D014481:United States
chemical_list: D010575:Pesticides; D012235:Rhodamines; C026188:rhodamine 6G; D012834:Silver; D006046:Gold