title: Direct effects of fatty meals and adiposity on oxidised low-density lipoprotein.
abstract: High-fat intake and high adiposity contribute to hyperlipaemia. In a hyperlipaemic state, lipoproteins infiltrate arterial wall where they are modified and cause an immune response characteristic of atherosclerosis. A small fraction of modified lipoproteins including oxidised low-density lipoprotein (ox-LDL) returns to circulation. The present study tracked high-fat meals during four weeks as to find effects of sustained frequency change on adiposity and ox-LDL. The findings indicated that changes in frequency of consumption of high-fat eating episodes correlated directly with changes in adiposity and ox-LDL. Hence the number of fatty meals consumed by people with overweight or obesity in few weeks could affect the atherogenic process.
authors: Medical Sciences Research Centre, Autonomous University of the State of Mexico, 205 Jesús Carranza, Toluca 50130, México. Electronic address: alagunaca@uaemex.mx.
authors: Antonio
authors: A
authors: Laguna-Camacho
authors: Medical Sciences Research Centre, Autonomous University of the State of Mexico, 205 Jesús Carranza, Toluca 50130, México.
authors: Arely S
authors: AS
authors: Alonso-Barreto
authors: Medical Sciences Research Centre, Autonomous University of the State of Mexico, 205 Jesús Carranza, Toluca 50130, México.
authors: Hugo
authors: H
authors: Mendieta-Zerón
mesh_terms: D050154:Adiposity; D000328:Adult; D050197:Atherosclerosis / Q000453:epidemiology / Q000208:ethnology / Q000209:etiology / Q000517:prevention & control; D018752:Diet, Fat-Restricted; D059305:Diet, High-Fat / Q000009:adverse effects* / Q000208:ethnology; D004038:Diet, Reducing; D005247:Feeding Behavior / Q000208:ethnology; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000208:ethnology / Q000209:etiology* / Q000503:physiopathology; D008077:Lipoproteins, LDL / Q000097:blood*; D008297:Male; D062407:Meals / Q000208:ethnology; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy / Q000208:ethnology / Q000209:etiology / Q000503:physiopathology; D050177:Overweight / Q000178:diet therapy / Q000208:ethnology / Q000209:etiology / Q000503:physiopathology; D010349:Patient Compliance / Q000208:ethnology; D012307:Risk Factors; D015854:Up-Regulation; D015431:Weight Loss / Q000208:ethnology
chemical_list: D008077:Lipoproteins, LDL; C099252:oxidized low density lipoprotein
keywords: Adiposity; Atherosclerosis; Behaviour frequency; Fatty meals; Oxidised low-density lipoprotein