title: Early and late optical coherence tomography findings following everolimus-eluting bioresorbable vascular scaffold implantation in myocardial infarction: a preliminary report.
abstract: BACKGROUND
  Although bioresorbable vascular scaffolds (BVS) have been used with promising results in patients with stable and unstable angina, little is known about the acute vascular response following BVS implantation in myocardial infarction. We present angiographic and OCT findings from the first patients undergoing bioresorbable vascular scaffold (BVS) implantation for non-ST-elevation myocardial infarction (NSTEMI) or ST-elevation myocardial infarction (STEMI) in our institution.
  
  
  METHODS
  The first 5 patients with NSTEMI and the first 5 patients with STEMI who underwent BVS implantation in our institution, followed by optical coherence tomography (OCT) imaging of the treated culprit vessel, were included in this series. All patients underwent angiographic analysis pre- and post- BVS implantation, as well as OCT analysis, including qualitative and quantitative assessment.
  
  
  RESULTS
  Implantation was successful in all cases, as assessed by angiography and OCT. There were no cases with coronary spasm, distal embolization or no-reflow. No adverse clinical events were recorded in any patient at the 6-month follow up. Specific illustrative cases demonstrating the challenges of BVS implantation in myocardial infarction are presented.
  
  
  CONCLUSIONS
  BVS implantation can potentially be used in the setting of thrombotic lesions encountered in myocardial infarction; however, the role of this treatment approach warrants systematic evaluation in prospective studies.
authors: Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands.
authors: Antonios
authors: A
authors: Karanasos
authors: Takashi
authors: T
authors: Muramatsu
authors: Roberto
authors: R
authors: Diletti
authors: Sjoerd
authors: S
authors: Nauta
authors: Yoshinobu
authors: Y
authors: Onuma
authors: Mattie
authors: M
authors: Lenzen
authors: Shimpei
authors: S
authors: Nakatani
authors: Nicolas M
authors: NM
authors: Van Mieghem
authors: Carl
authors: C
authors: Schultz
authors: Peter P
authors: PP
authors: De Jaegere
authors: Patrick W
authors: PW
authors: Serruys
authors: Felix
authors: F
authors: Zijlstra
authors: Evelyn
authors: E
authors: Regar
authors: Robert-Jan
authors: RJ
authors: van Geuns
mesh_terms: D020341:Absorbable Implants; D000368:Aged; D001807:Blood Vessel Prosthesis; D017023:Coronary Angiography / Q000379:methods; D054855:Drug-Eluting Stents; D000068338:Everolimus / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000601:surgery*; D062645:Percutaneous Coronary Intervention / Q000295:instrumentation / Q000379:methods; D011182:Postoperative Care / Q000379:methods; D015203:Reproducibility of Results; D054457:Tissue Scaffolds; D041623:Tomography, Optical Coherence / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000068338:Everolimus