title: Science to practice: myeloperoxidase immunoradiology improves detection of acute and chronic experimental multiple sclerosis.
abstract: The report by Pulli et al ( 1 ) provides good preclinical evidence that MPO-Gd, a gadolinium-based magnetic resonance (MR) imaging probe for the enzyme myeloperoxidase (MPO), might be a more sensitive contrast agent for the detection of multiple sclerosis (MS) and may mark a pathologically specific proinflammatory component of the disease that might also provide the basis for novel therapies.
authors.affiliation: Department of Radiology University of Pennsylvania Health System 3600 Market St, Suite 370 Philadelphia, PA 19104.
authors.forename: R Nick
authors.initials: RN
authors.lastname: Bryan
mesh_terms: D000818:Animals; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D009103:Multiple Sclerosis / Q000000981:diagnostic imaging* / Q000276:immunology*; D009195:Peroxidase / Q000032:analysis*; D011877:Radionuclide Imaging
chemical_list: D003287:Contrast Media; D009195:Peroxidase; D019786:Gadolinium DTPA