title: Chemical and physical factors influencing the dynamics of differentiation in embryonic stem cells.
abstract: Differentiating embryonic stem cells into a specific lineage or cell type is one of the most investigated areas of stem cell research; however it is wrought with hurdles. The differentiation process during embryogenesis is greatly influenced by physiochemical factors. They direct key genes for lineage commitment, which in turn are responsible for patterning into highly organized tissues resulting in organ formation. In this review, we have focused on the influence of physiochemical factors on the differentiation process in embryonic stem cells, which mimics, embryogenesis in vivo.
authors.forename: Saras
authors.initials: S
authors.lastname: Jyoti
authors.affiliation: Amity Directorate of Science and Innovation, Amity University,Sector 125 Noida, UP , India -201313. standon1@amity.edu.
authors.forename: Simran
authors.initials: S
authors.lastname: Tandon
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D019069:Cell Respiration; D048430:Cell Shape; D002478:Cells, Cultured; D003470:Culture Media; D016207:Cytokines / Q000502:physiology; D053595:Embryonic Stem Cells / Q000502:physiology*; D005109:Extracellular Matrix / Q000502:physiology; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000502:physiology
chemical_list: D003470:Culture Media; D016207:Cytokines; D036341:Intercellular Signaling Peptides and Proteins