title: A New Approach to Nitrones through Cascade Reaction of Nitro Compounds Enabled by Visible Light Photoredox Catalysis.
abstract: A series of nitroalkanes were efficiently transformed to alkylnitrones using a visible light irradiation photocatalytic process. The mild, efficient, and environmentally benign reaction method, involving dynamic reciprocations of cascade pathways, comprises a mixture of a Ru(bpy)3Cl2 photoredox catalyst and DIPIBA or Hünig's base in CH3CN. Notably, DIPIBA was found to be the best additive for the cross condensation reaction of nitroalkanes with aldehydes. The structures of appropriate products were confirmed by X-ray analysis.
authors.affiliation: †Department of Chemistry and Biochemistry, National Chung Cheng University, Chia-Yi, 621, Taiwan, R.O.C.
authors.forename: Cheng-Wei
authors.initials: CW
authors.lastname: Lin
authors.affiliation: †Department of Chemistry and Biochemistry, National Chung Cheng University, Chia-Yi, 621, Taiwan, R.O.C.
authors.forename: Bor-Cherng
authors.initials: BC
authors.lastname: Hong
authors.affiliation: †Department of Chemistry and Biochemistry, National Chung Cheng University, Chia-Yi, 621, Taiwan, R.O.C.
authors.forename: Wan-Chen
authors.initials: WC
authors.lastname: Chang
authors.affiliation: ‡Instrumentation Center, National Taiwan University, Taipei, 106, Taiwan, R.O.C.
authors.forename: Gene-Hsiang
authors.initials: GH
authors.lastname: Lee
mesh_terms: D000473:Alkanes / Q000737:chemistry*; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry; D008027:Light; D015394:Molecular Structure; D009574:Nitro Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D009589:Nitrogen Oxides / Q000138:chemical synthesis* / Q000737:chemistry*; D010084:Oxidation-Reduction; D055668:Photochemical Processes; D012428:Ruthenium / Q000737:chemistry
chemical_list: D000473:Alkanes; D056831:Coordination Complexes; D009574:Nitro Compounds; D009589:Nitrogen Oxides; C015388:nitrones; D012428:Ruthenium