title: [The detection of thrombocyte-bound IgG in patients with throbocytopenia].
abstract: The article presents the mode of detection of anti-thrombocyte auto-antibodies using flow cytometry technique. The values of IgG conjugated with thrombocytes are established in healthy persons. The rate of frequency of auto-antibodies to thrombocytes is analyzed in patients with primarily diagnosed immune thrombocytopenia, with relapse of disease and after therapy of immune thrombocytopenia. The carried out studies demonstrate that flow cytometry technique has a high sensitivity to detect thrombocyte-related antibodies and can be applied under examination of patients with thrombocytopenia.
authors.forename: E V
authors.initials: EV
authors.lastname: Butina
authors.forename: G A
authors.initials: GA
authors.lastname: Zaĭtseva
authors.forename: N V
authors.initials: NV
authors.lastname: Isaeva
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies / Q000097:blood*; D001792:Blood Platelets / Q000378:metabolism* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood* / Q000473:pathology; D013921:Thrombocytopenia / Q000097:blood* / Q000473:pathology
chemical_list: D001323:Autoantibodies; D007074:Immunoglobulin G