title: Secondary Metabolites Control the Associated Bacterial Communities of Saprophytic Basidiomycotina Fungi.
abstract: Fungi grow under humid conditions and are, therefore, prone to biofilm infections. A 16S rRNA fingerprint analysis was performed on 49 sporocarps of Basidiomycotina in order to determine whether they are able to control these biofilms. Ninety-five bacterial phylotypes, comprising 4 phyla and 10 families, were identified. While ectomycorrhizal fungi harbored the highest bacterial diversity, saprophytic fungi showed little or no association with bacteria. Seven fungal species were screened for antimicrobial and antibiofilm activities. Biofilm formation and bacterial growth was inhibited by extracts obtained from saprophytic fungi, which confirmed the hypothesis that many fungi modulate biofilm colonization on their sporocarps.
authors.affiliation: Helmholtz Centre for Infection Research, Chemical Microbiology.
authors.forename: Maira Peres
authors.initials: MP
authors.lastname: de Carvalho
authors.forename: Patrick
authors.initials: P
authors.lastname: Türck
authors.forename: Wolf-Rainer
authors.initials: WR
authors.lastname: Abraham
mesh_terms: D000900:Anti-Bacterial Agents / Q000378:metabolism*; D001419:Bacteria / Q000187:drug effects / Q000254:growth & development*; D001487:Basidiomycota / Q000378:metabolism*; D018441:Biofilms / Q000187:drug effects / Q000254:growth & development*; D058448:Biota; D016000:Cluster Analysis; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D056265:Microbial Interactions; D008969:Molecular Sequence Data; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D064210:Secondary Metabolism; D017422:Sequence Analysis, DNA
chemical_list: D000900:Anti-Bacterial Agents; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S