title: Effects of gentiana scabra bage on expression of hepatic type I, III collagen proteins in Paragonimus skrjabini rats with liver fibrosis.
abstract: OBJECTIVE
  To explore the effects of gentiana scabra bage on the expression of hepatic collagen proteins in Paragonimus skrjabini rats with liver fibrosis.
  
  
  METHODS
  Immunohistochemical technique was used to observe the changes of content of hepatic type I, III collagen proteins in Paragonimus skrjabini rats with liver fibrosis before and after the gentiana scabra bage treatmeat.
  
  
  RESULTS
  Comparing with the model group, changes of hepatic type I and type III collagen proteins in gentiana scabra bage treated group were significantly weakened.
  
  
  CONCLUSIONS
  Gentiana scabra bage treatment can reduce the content of hepatic type III and type I collagen protein significantly in Paragonimus skrjabini rats with liver fibrosis, thereby, playing the role against hepatic fibrosis.
authors.affiliation: Zhenjiang Medical School, Zhenjiang 212004, China.
authors.forename: Zhao-Xia
authors.initials: ZX
authors.lastname: Qu
authors.affiliation: Yuncheng Nursing Vocational College, Yuncheng 043100, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Li
authors.affiliation: First People's Hospital in Zhenjiang, Zhenjiang 212002, China.
authors.forename: Chao-Dong
authors.initials: CD
authors.lastname: Ma
authors.affiliation: Department of Parasitology, Faculty of Basic Medicine, Kunming Medical University, Kunming 650500, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Biochemistry and Molecular Biology, Faculty of Basic Medicine, Kunming Medical University, Kunming 650500, China.
authors.forename: Shu-De
authors.initials: SD
authors.lastname: Li
authors.affiliation: Department of Parasitology, Faculty of Basic Medicine, Kunming Medical University, Kunming 650500, China. Electronic address: wenlinwang331@163.com.
authors.forename: Wen-Lin
authors.initials: WL
authors.lastname: Wang
keywords: Collagen protein I; Collagen protein III; Gentiana scabra bage; Liver fibrosis; Paragonimus skrjabini