title: Association between self-perception period of lower urinary tract symptoms and International Prostate Symptom Score: a propensity score matching study.
abstract: BACKGROUND
  Most studies focusing on progression of BPH have been limited to the relationship between age and BPH progression, and only few studies have focused on the time duration to start treatment. This study aimed to investigate the association between self-perception period (S-PP) of lower urinary tract symptoms (LUTS) and International Prostate Symptom Score (IPSS).
  
  
  METHODS
  This study used data from two large-population surveys: a community-based survey and a university hospital outpatient-based interview survey. Both surveys were conducted in male subjects aged 40 years or older who gave consent to the survey questionnaire and voluntarily expressed their intention to participate. Propensity score matching (PSM) was used to organize the population in both surveys into randomized groups to reduce selection bias. After excluding those who had missing values, 483 subjects were assigned to each group by PSM.
  
  
  RESULTS
  The S-PP of LUTS became significantly longer as the severity of LUTS increased. The S-PP was 4.15 years in the mild group, 4.36 years in the moderate group, and 6.23 years in the severe group. These differences were statistically significant. The correlation between S-PP of LUTS and IPSS was measured by partial correlation while controlling for age (correlation coefficient = 0.20, p <0.001). Multiple regression analysis after controlling for age revealed that one-year increase in the S-PP of LUTS significantly (p <0.001) increased IPSS by 0.322 points.
  
  
  CONCLUSIONS
  This study clarified the association between S-PP of LUTS and IPSS in a large-scale population. These findings suggest that, from the perspective of public health, S-PP is an important risk factor for LUTS progression.
authors.affiliation: Department of Epidemiology and Medical Informatics, Korea University, Seoul, South Korea. sungryul.shim@gmail.com.
authors.forename: Sung Ryul
authors.initials: SR
authors.lastname: Shim
authors.affiliation: Department of Urology, Soonchunhyang University College of Medicine, Seoul Hospital, Seoul, South Korea. piacekjh@hanmail.net.
authors.forename: Jae Heon
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Urology, Korea University College of Medicine, Ansan Hospital, Ansan, South Korea. doc71377@naver.com.
authors.forename: Hoon
authors.initials: H
authors.lastname: Choi
authors.affiliation: Department of Urology, Korea University College of Medicine, Ansan Hospital, Ansan, South Korea. uronae@genetheraqpy.or.kr.
authors.forename: Jae Hyun
authors.initials: JH
authors.lastname: Bae
authors.affiliation: Department of Preventive Medicine, College of Medicine, Korea University, Seoul, South Korea. kimhj@korea.ac.kr.
authors.forename: Hae Joon
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Biomedical Research Center, Seoul National University Bundang Hospital, Seongnam, South Korea. qrio1010@gmail.com.
authors.forename: Soon-Sun
authors.initials: SS
authors.lastname: Kwon
authors.affiliation: Department of Preventive Medicine, College of Medicine, Korea University, Seoul, South Korea. chun@korea.ac.kr.
authors.forename: Byung Chul
authors.initials: BC
authors.lastname: Chun
authors.affiliation: Department of Preventive Medicine, College of Medicine, Korea University, Seoul, South Korea. leewj@korea.ac.kr.
authors.forename: Won Jin
authors.initials: WJ
authors.lastname: Lee
mesh_terms: D000328:Adult; D018450:Disease Progression; D005260:Female; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000175:diagnosis*; D008297:Male; D015995:Prevalence; D057216:Propensity Score; D011470:Prostatic Hyperplasia / Q000453:epidemiology; D012307:Risk Factors; D012649:Self Concept; D011795:Surveys and Questionnaires