title: Renal failure after coronary bypass surgery and the associated risk factors.
abstract: OBJECTIVE
  We aimed to evaluate the risk factors associated with acute renal failure in patients who underwent coronary artery bypass surgery.
  
  
  METHODS
  One hundred and six patients who developed renal failure after coronary artery bypass grafting (CABG) constituted the study group (RF group), while 110 patients who did not develop renal failure served as a control group (C group). In addition, the RF group was divided into two subgroups: patients that were treated with conservative methods without the need for hemodialysis (NH group) and patients that required hemodialysis (HR group). Risk factors associated with renal failure were investigated.
  
  
  RESULTS
  Among the 106 patients that developed renal failure (RF), 80 patients were treated with conservative methods without any need for hemodialysis (NH group); while 26 patients required hemodialysis in the postoperative period (HR group). The multivariate analysis showed that diabetes mellitus and the postoperative use of positive inotropes and adrenaline were significant risk factors associated with development of renal failure. In addition, carotid stenosis and postoperative use of adrenaline were found to be significant risk factors associated with hemodialysis-dependent renal failure (P &lt; .05). The mortality in the RF group was determined as 13.2%, while the mortality rate in patients who did not require hemodialysis and those who required hemodialysis was 6.2% and 34%, respectively.
  
  
  CONCLUSIONS
  Renal failure requiring hemodialysis after CABG often results in high morbidity and mortality. Factors affecting microcirculation and atherosclerosis, like diabetes mellitus, carotid artery stenosis, and postoperative vasopressor use remain the major risk factors for the development of renal failure.
authors.affiliation: Department of Cardiovascular Surgery, Private Tınaztepe Hospital, İzmir. Email:hreyhanoglu@hotmail.com.
authors.forename: Hasan
authors.initials: H
authors.lastname: Reyhanoglu
authors.affiliation: Department of Cardiovascular Surgery, Private Tınaztepe Hospital, İzmir. Email:hreyhanoglu@hotmail.com.
authors.forename: Kaan
authors.initials: K
authors.lastname: Ozcan
authors.affiliation: Department of Cardiovascular Surgery, Private Tınaztepe Hospital, İzmir. Email:hreyhanoglu@hotmail.com.
authors.forename: Murat
authors.initials: M
authors.lastname: Erturk
authors.affiliation: Department of Cardiovascular Surgery, Ege University Medical Faculty, İzmir, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: İslamoglu
authors.affiliation: Department of Cardiovascular Surgery, Private Tınaztepe Hospital, İzmir. Email:hreyhanoglu@hotmail.com.
authors.forename: İsa
authors.initials: İ
authors.lastname: Durmaz
mesh_terms: D015984:Causality; D015897:Comorbidity; D001026:Coronary Artery Bypass / Q000401:mortality* / Q000706:statistics & numerical data*; D003324:Coronary Artery Disease / Q000401:mortality* / Q000601:surgery*; D048909:Diabetes Complications / Q000401:mortality*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D051437:Renal Insufficiency / Q000401:mortality*; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D014421:Turkey / Q000453:epidemiology