title: [Chemical constituents from Artemisia annua].
abstract: OBJECTIVE
  To investigate the chemical constituents of dried whole plants of Artemisia annua.
  
  
  METHODS
  The chemical constituents were isolated by repeated silica gel chromatography, medium pressure column chromatography, and semi-preparative HPLC, and their structures were elucidated by spectroscopic analyses and comparison of NMR data with those reported in literature.
  
  
  RESULTS
  15 compounds were isolated and identified to be 5-O-[(E)-Caffeoyl] quinic acid(l), 1,3-di-O-caffeoylquinic acid(2), 4 5-di-O-caffeoylquinic acid(3), 3, 5-di-O-caffeoylquinic acid (4), 3, 4-di-O-caffeoylquinic acid (5), methyl-3,4-di-O-caffeoylquinic acid(6), methyl-3,5-di-O-caffeoylquinic acid(7), 3,6'-O-diferuloylsucrose(8), 5'-β-D-glucopyranosyloxyjasmonic acid(9), Scopoletin(10), scoparone (11), 4-O-β-D-glucopyranosyl-2-hydroxyl-6-methoxyacetophenone (12), chrysosplenol D (13), casticin (14), chrysosplenetin(15).
  
  
  CONCLUSIONS
  Compounds 2, 6, 8 and 9 are obtained from the Artemisia genus for the first time. Compounds 7 and 15 are obtained from this plant for the first time.
authors.forename: Yi-wu
authors.initials: YW
authors.lastname: Zhao
authors.forename: Fu-yong
authors.initials: FY
authors.lastname: Ni
authors.forename: Ya-ling
authors.initials: YL
authors.lastname: Song
authors.forename: Sheng-yang
authors.initials: SY
authors.lastname: Wang
authors.forename: Wen-zhe
authors.initials: WZ
authors.lastname: Huang
authors.forename: Zhen-zhong
authors.initials: ZZ
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Xiao
mesh_terms: D031172:Artemisia annua / Q000737:chemistry*; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification; D008516:Medicine, Chinese Traditional; D010946:Plants, Medicinal; D011801:Quinic Acid / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D058428:Silica Gel
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids; C472707:caffeoylquinic acid; D011801:Quinic Acid; D058428:Silica Gel; C054133:casticin; C570121:chrysosplenetin