title: Role of laccase from Coriolus versicolor MTCC-138 in selective oxidation of aromatic methyl group.
abstract: Now a day, laccases are the most promising enzymes in the area of biotechnology and synthesis. One of the best applications of laccases is the selective oxidation of aromatic methyl group to aldehyde group. Such transformations are valuable because it is difficult to stop the reaction at aldehyde stage. Chemical methods used for such biotransformations areexpensive and give poor yields. But, the laccase-catalyzed biotransformations of such type are non-expensive and yield is excellent. Authors have used crude laccase obtained from the liquid culture growth medium of fungal strain Coriolus versicolor MTCC-138 for the biotransformations of toluene, 3-nitrotoluene, and 4-chlorotoluene to benzaldehyde, 3-nitrobenzaldehyde, and 4-chlorobenzaldehyde, respectively, instead of purified laccase because purification process requires much time and cost. This communication reports that crude laccase can also be used in the place of purified laccase as effective biocatalyst.
authors.forename: Pankaj Kumar
authors.initials: PK
authors.lastname: Chaurasia
authors.forename: Sunil Kumar
authors.initials: SK
authors.lastname: Singh
authors.forename: Shashi Lata
authors.initials: SL
authors.lastname: Bharati
mesh_terms: D001547:Benzaldehydes / Q000737:chemistry; D001709:Biotechnology; D001711:Biotransformation; D055453:Coriolaceae / Q000201:enzymology*; D003470:Culture Media; D042845:Laccase / Q000737:chemistry* / Q000378:metabolism; D010084:Oxidation-Reduction; D014050:Toluene / Q000031:analogs & derivatives / Q000737:chemistry
chemical_list: D001547:Benzaldehydes; D003470:Culture Media; D014050:Toluene; C052044:4-chlorobenzaldehyde; D042845:Laccase; C050571:3-nitrobenzaldehyde; C029049:4-chlorotoluene