title: Guanosine radical reactivity explored by pulse radiolysis coupled with transient electrochemistry.
abstract: We follow the reactivity of a guanosine radical created by a radiolytic electron pulse both by spectroscopic and electrochemical methods. This original approach allows us to demonstrate that there is a competition between oxidation and reduction of these intermediates, an important result to further analyse the degradation or repair pathways of DNA bases.
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, UMR 8235, Laboratoire Interfaces et Systèmes Electrochimiques, F-75005 Paris, France. emmanuel.maisonhaute@upmc.fr.
authors.forename: A
authors.initials: A
authors.lastname: Latus
authors.forename: M S
authors.initials: MS
authors.lastname: Alam
authors.forename: M
authors.initials: M
authors.lastname: Mostafavi
authors.forename: J-L
authors.initials: JL
authors.lastname: Marignier
authors.forename: E
authors.initials: E
authors.lastname: Maisonhaute
mesh_terms: D001966:Bromine / Q000737:chemistry; D004563:Electrochemistry; D005609:Free Radicals / Q000737:chemistry*; D006151:Guanosine / Q000737:chemistry*; D010084:Oxidation-Reduction; D011675:Pulse Radiolysis; D012834:Silver / Q000737:chemistry
chemical_list: D005609:Free Radicals; D006151:Guanosine; D012834:Silver; D001966:Bromine