title: Chorangioendothelioma of the Placenta: A Myth or Reality?
abstract: Chorangiomas of the placenta are often discovered incidentally and, although they are not common (1 in 9000 to 1 in 50 000 placentas), these tumors may be found in 0.5% to 1% of carefully examined placentas. The vast majority are of no clinical importance and complications are seen only in association with tumors measuring more than 4 cm in diameter. In contrast, hemangioendotheliomas are vascular tumors with varying grades of malignant potential and hardly ever involve the placenta. Here we describe a large placental chorangioma causing fetal hydrops and demonstrating distinctive intravascular luminal endothelial proliferation and tufting. To the best of our knowledge, this is probably only the second case of a placental hemangioendothelioma reported in the literature.
authors.affiliation: 1 Department of Anatomic and Perinatal Pathology and Cytology, Fernandez Hospital Unit 3, Plot 769, Road No. 44, Jubilee Hills, Hyderabad - 500033, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Jaiman
authors.affiliation: 2 Department of Obstetrics, Fernandez Hospital Unit 3, Plot 769, Road No. 44, Jubilee Hills, Hyderabad - 500033, India.
authors.forename: Evita
authors.initials: E
authors.lastname: Fernandez
authors.affiliation: 3 Department of Gynaecology, Fernandez Hospital Unit 3, Plot 769, Road No. 44, Jubilee Hills, Hyderabad - 500033, India.
authors.forename: Sirisha Rao
authors.initials: SR
authors.lastname: Gundabattula
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D016640:Diabetes, Gestational; D005260:Female; D006390:Hemangioendothelioma / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D010922:Placenta Diseases / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: chorangioendothelioma; chorangioma; hemangioendothelioma; hydrops fetalis; placental tumor; vascular lesion