title: [Breast cancer developing during pregnancy--clinical cases and review of the literature].
abstract: The goal of the present paper is to discuss diagnosis, treatment approaches and histopathologic characteristics of breast cancer developing during pregnancy, based on our results and published literature data. We retrospectively evaluated clinical and pathologic features of tumors, treatment methods, decisions related to pregnancy and final outcome by eight pregnant patients with breast cancer. The patients' age varied from 26 to 36 years. At the last medical examination in October 2013, three among all eight patients were alive, two of them were without local and distant recurrence, and one patient has distant metastases and is carrying out a treatment. The aim of this paper was to discuss the characteristics of breast cancer developing during pregnancy. Retrospectively have been analyzed clinical-pathological characteristics of the tumors in eight pregnant women with breast cancer, the treatment, the management of the pregnancy, and the final outcome. The results are analyzed by comparing with data published in the literature.
authors.forename: E
authors.initials: E
authors.lastname: Alexandrova
authors.forename: S
authors.initials: S
authors.lastname: Sergieva
authors.forename: P
authors.initials: P
authors.lastname: Kostova
authors.forename: I
authors.initials: I
authors.lastname: Michailova
authors.forename: K
authors.initials: K
authors.lastname: Timcheva
authors.forename: M
authors.initials: M
authors.lastname: Taushanova
authors.forename: A
authors.initials: A
authors.lastname: Milev
mesh_terms: D000328:Adult; D001940:Breast / Q000187:drug effects / Q000473:pathology* / Q000528:radiation effects / Q000601:surgery; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D011379:Prognosis; D011878:Radiotherapy; D012189:Retrospective Studies; D016896:Treatment Outcome