title: Unexplained early-onset lacunar stroke and inflammatory skin lesions: Consider ADA2 deficiency.
authors.affiliation: From Academic Medical Center (W.F.W., P.J.N., A.E.H.), Amsterdam, the Netherlands; National Institutes of Health (I.A.), National Human Genome Research Institute, Bethesda, MD; and University Medical Center Utrecht (K.D.L., K.P.J.B.), the Netherlands. w.f.westendorp@amc.nl.
authors.forename: Willeke F
authors.initials: WF
authors.lastname: Westendorp
authors.affiliation: From Academic Medical Center (W.F.W., P.J.N., A.E.H.), Amsterdam, the Netherlands; National Institutes of Health (I.A.), National Human Genome Research Institute, Bethesda, MD; and University Medical Center Utrecht (K.D.L., K.P.J.B.), the Netherlands.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Nederkoorn
authors.affiliation: From Academic Medical Center (W.F.W., P.J.N., A.E.H.), Amsterdam, the Netherlands; National Institutes of Health (I.A.), National Human Genome Research Institute, Bethesda, MD; and University Medical Center Utrecht (K.D.L., K.P.J.B.), the Netherlands.
authors.forename: Ivona
authors.initials: I
authors.lastname: Aksentijevich
authors.affiliation: From Academic Medical Center (W.F.W., P.J.N., A.E.H.), Amsterdam, the Netherlands; National Institutes of Health (I.A.), National Human Genome Research Institute, Bethesda, MD; and University Medical Center Utrecht (K.D.L., K.P.J.B.), the Netherlands.
authors.forename: A Elisabeth
authors.initials: AE
authors.lastname: Hak
authors.affiliation: From Academic Medical Center (W.F.W., P.J.N., A.E.H.), Amsterdam, the Netherlands; National Institutes of Health (I.A.), National Human Genome Research Institute, Bethesda, MD; and University Medical Center Utrecht (K.D.L., K.P.J.B.), the Netherlands.
authors.forename: Klaske D
authors.initials: KD
authors.lastname: Lichtenbelt
authors.affiliation: From Academic Medical Center (W.F.W., P.J.N., A.E.H.), Amsterdam, the Netherlands; National Institutes of Health (I.A.), National Human Genome Research Institute, Bethesda, MD; and University Medical Center Utrecht (K.D.L., K.P.J.B.), the Netherlands.
authors.forename: Kees P J
authors.initials: KP
authors.lastname: Braun
mesh_terms: D000243:Adenosine Deaminase / Q000172:deficiency* / Q000235:genetics*; D000367:Age Factors; D002648:Child; D003872:Dermatitis / Q000150:complications / Q000175:diagnosis* / Q000235:genetics*; D006720:Homozygote; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000172:deficiency* / Q000235:genetics*; D008297:Male; D009154:Mutation; D059409:Stroke, Lacunar / Q000150:complications / Q000175:diagnosis* / Q000235:genetics*
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; C408373:ADA2 protein, human; D000243:Adenosine Deaminase