title: Synthesis of naked amino-pyrroloindoline via direct aminocyclization of tryptamine.
abstract: The first direct access to unprotected amino-pyrroloindoline via aminocyclization of tryptamine and tryptophan has been described. A variety of structurally diverse amino-pyrroloindolines are furnished by the use of O-(2,4-dinitrophenyl)hydroxylamine (DPH) as the nitrogen source in the presence of catalytic Rh2(esp)2.
authors.affiliation: State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, Center of Drug Discovery, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China. yslai@cpu.edu.cn.
authors.forename: Zhigao
authors.initials: Z
authors.lastname: Shen
authors.forename: Zilei
authors.initials: Z
authors.lastname: Xia
authors.forename: Huijun
authors.initials: H
authors.lastname: Zhao
authors.forename: Jiadong
authors.initials: J
authors.lastname: Hu
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Wan
authors.forename: Yisheng
authors.initials: Y
authors.lastname: Lai
authors.forename: Chen
authors.initials: C
authors.lastname: Zhu
authors.forename: Weiqing
authors.initials: W
authors.lastname: Xie
mesh_terms: D000470:Alkaloids / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D014363:Tryptamines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000470:Alkaloids; D000588:Amines; D007211:Indoles; D011758:Pyrroles; D014363:Tryptamines; C030820:tryptamine