title: Comparison of T2 Values in the Lateral and Medial Portions of the Weight-Bearing Cartilage of the Hip for Patients With Symptomatic Femoroacetabular Impingement and Asymptomatic Volunteers.
abstract: OBJECTIVE
  To develop a simplified method to define a clinically relevant subregion in the course of arthroscopic treatment of femoroacetabular impingement (FAI) using T2 mapping in patients and asymptomatic volunteers. Additionally, we sought to compare the lateral and medial subregion values in asymptomatic volunteers and in patients presenting with FAI. Finally, we wanted to investigate possible associations between patients' T2 mapping values and demographic variables-i.e., alpha angle, age, sex, and body mass index (BMI).
  
  
  METHODS
  Twenty-five asymptomatic volunteers and 23 consecutive symptomatic patients with FAI (cam or mixed type) were prospectively enrolled and evaluated with a sagittal T2 mapping sequence. The weight-bearing region of the acetabular and femoral cartilage was manually segmented and divided into medial and lateral subregions. Median T2 values were determined, and patient characteristics were assessed as potential predictors of T2 values.
  
  
  RESULTS
  T2 values in the lateral portion of the acetabulum were lower than in the medial portion for both asymptomatic volunteers (43 v 53 ms; P < .001) and patients with FAI (42 v 49 ms; P = .016). The medial acetabulum (MA) of asymptomatic volunteers had higher T2 values than those of the FAI group (53 v 49 ms; P = .040). The lateral-minus-medial difference was significantly larger among asymptomatic volunteers than in patients with FAI (P = .047). Patients with FAI had higher alpha angles than those of the asymptomatic volunteers, but no other associations with patient characteristics were observed.
  
  
  CONCLUSIONS
  This study's findings suggest that there are differences in cartilage T2 mapping values between medial and lateral weight-bearing aspects of the hip and may expand the application and usefulness of biochemical magnetic resonance imaging (MRI) techniques, specifically T2 mapping, in the diagnosis of hip cartilage damage with the evaluation of clinically relevant subregions. When comparing asymptomatic volunteers and patients with FAI presenting with cam or mixed type deformity, we observed a significant contrast between the T2 mapping values of the lateral and medial portions of the weight-bearing zone of the acetabular cartilage, whereas such contrast was not observed when zone 3 was analyzed as a whole.
  
  
  METHODS
  Level III, development of diagnostic criteria on the basis of consecutive patients with a universally applied reference gold standard.
authors.affiliation: Steadman Philippon Research Institute, Vail, Colorado, U.S.A.
authors.forename: Fernando P
authors.initials: FP
authors.lastname: Ferro
authors.affiliation: Steadman Philippon Research Institute, Vail, Colorado, U.S.A.
authors.forename: Charles P
authors.initials: CP
authors.lastname: Ho
authors.affiliation: Steadman Philippon Research Institute, Vail, Colorado, U.S.A.
authors.forename: Grant J
authors.initials: GJ
authors.lastname: Dornan
authors.affiliation: Steadman Philippon Research Institute, Vail, Colorado, U.S.A.
authors.forename: Rachel K
authors.initials: RK
authors.lastname: Surowiec
authors.affiliation: The Steadman Clinic, Vail, Colorado, U.S.A.. Electronic address: MJP@sprivail.org.
authors.forename: Marc J
authors.initials: MJ
authors.lastname: Philippon
mesh_terms: D000077:Acetabulum / Q000473:pathology; D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D002358:Cartilage, Articular / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D016022:Case-Control Studies; D005260:Female; D057925:Femoracetabular Impingement / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016474:Weight-Bearing / Q000502:physiology; D055815:Young Adult