title: Known knowns, known unknowns, and unknown unknowns: can systems medicine provide a new approach to sepsis?
authors.affiliation: Department of Cardiovascular Sciences Diagnostic Development Unit, University of Leicester and UHL NHS Trust, Leicester Royal Infirmary, Leicester, UK jt23@le.ac.uk.
authors.forename: J P
authors.initials: JP
authors.lastname: Thompson
authors.affiliation: Department of Cardiovascular Sciences Diagnostic Development Unit, University of Leicester and UHL NHS Trust, Leicester Royal Infirmary, Leicester, UK.
authors.forename: T J
authors.initials: TJ
authors.lastname: Coats
authors.affiliation: Department of Physics and Astronomy, University of Leicester, UK Diagnostic Development Unit, University of Leicester and UHL NHS Trust, Leicester Royal Infirmary, Leicester, UK.
authors.forename: M R
authors.initials: MR
authors.lastname: Sims
mesh_terms: D000776:Anesthesiology; D015415:Biomarkers; D006801:Humans; D008991:Monitoring, Physiologic; D018805:Sepsis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*
chemical_list: D015415:Biomarkers