title: Evaluation of palatal donor site haemostasis and wound healing after free gingival graft surgery.
abstract: OBJECTIVE
  Evaluating effectiveness of a medicinal plant extract (MPE) in achieving haemostasis and early wound healing at free gingival graft (FGG) donor site in a randomized controlled fashion.
  
  
  METHODS
  Forty patients requiring FGG at lower anterior area were randomly assigned into two groups. FGG was performed to all patients and following graft procurement; wet gauze (WG) was applied alone (control: WG group) or with MPE (test: MPE + WG group) for haemostasis. Donor site working time, bleeding (BLE), colour match (CM), pain, epithelization (EP) and sensation loss (SL) were evaluated.
  
  
  RESULTS
  Thirty-three participants completed a 6-month period study. In the test group, primary BLE was shorter (p < 0.001) and fewer individuals showed secondary BLE during 3 days (p < 0.001). During the 6 days, pain scores were higher in WG patients (p < 0.05). Later on, no inter-group difference was observed. EP was relatively faster (p < 0.001) and CM was slightly better (p < 0.05) in MPE + WG group.
  
  
  CONCLUSIONS
  MPE provided faster and continuous haemostasis that made a positive contribution to the early soft tissue healing to some extent but due to limitations; further trials are needed to demonstrate the efficiency of this material.
authors.affiliation: Periodontology Department, Faculty of Dentistry, Hacettepe University, Ankara, Turkey.
authors.forename: Huseyin Gencay
authors.initials: HG
authors.lastname: Keceli
authors.affiliation: Periodontology Department, Faculty of Dentistry, Kirikkale University, Kirikkale, Turkey.
authors.forename: Bahadir Ugur
authors.initials: BU
authors.lastname: Aylikci
authors.affiliation: Periodontology Department, Faculty of Dentistry, Katip Celebi University, Izmir, Turkey.
authors.forename: Serhat
authors.initials: S
authors.lastname: Koseoglu
authors.affiliation: Biostatistics Department, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: Anil
authors.initials: A
authors.lastname: Dolgun
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical; D003116:Color; D005260:Female; D005500:Follow-Up Studies; D058752:Free Tissue Flaps / Q000637:transplantation*; D005881:Gingiva / Q000637:transplantation*; D005893:Gingivoplasty / Q000379:methods; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D061646:Operative Time; D006472:Oral Hemorrhage / Q000209:etiology; D010147:Pain Measurement / Q000379:methods; D010149:Postoperative Pain / Q000209:etiology; D010159:Palate / Q000601:surgery*; D008517:Phytotherapy / Q000379:methods*; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal; D011446:Prospective Studies; D062326:Re-Epithelialization / Q000502:physiology; D012677:Sensation / Q000502:physiology; D060053:Transplant Donor Site / Q000601:surgery*; D014945:Wound Healing / Q000502:physiology; D055815:Young Adult
chemical_list: D006490:Hemostatics; D010936:Plant Extracts; C539751:ankaferd blood stopper
keywords: donor site; free gingival graft; haemostasis; palatal healing; wound healing