title: Cardiovascular disease in human immunodeficiency virus-infection as a cause of hospitalization: a case-series in a General Hospital in Peru.
abstract: BACKGROUND
  Cardiovascular disease in the context of human immunodeficiency virus infection has become a major clinical concern in recent years. In the current report we assess hospitalizations due to cardiovascular disease in human immunodeficiency virus patients in a Social Security reference hospital in Peru.
  
  
  METHODS
  A retrospective study was carried out between January 1996 and December 2012 in a General Hospital in Lima, Peru.
  
  
  RESULTS
  We included 26 patients hospitalized due to cardiovascular disease. Mean age was 46.3 years (SD 12.5), predominantly male (57.7%). Ten patients (38.4%) were in Acquired Immunodeficiency Syndrome stages. Seventeen (65.4%) received high-active-antiretroviral therapy. Eleven (42.3%) had cardiac involvement and 15 (57.7%) had non-cardiac vascular involvement. The most frequent causes of cardiac involvement were pericardial effusion and myocardial infarction. On the other hand, deep vein thrombosis and stroke were the most frequent for non-cardiac vascular involvement.
  
  
  CONCLUSIONS
  Cardiovascular disease is an important cause of hospitalization in Peruvian human immunodeficiency virus patients, with differences between immunosuppression stages. Further studies analyzing associated factors are warranted.
authors.affiliation: Clínica Médica Cayetano Heredia, Lima, Peru. Electronic address: germanvrodriguez@yahoo.com.
authors.forename: Germán
authors.initials: G
authors.lastname: Valenzuela-Rodríguez
authors.affiliation: Unidad de Generación y Análisis de Evidencias en Salud Pública (UNAGESP), Instituto Nacional de Salud, Lima, Peru; School of Medicine, Universidad Peruana de Ciencias Aplicadas, Lima, Peru. Electronic address: emezones@gmail.com.
authors.forename: Edward
authors.initials: E
authors.lastname: Mezones-Holguín
authors.affiliation: Infectious Diseases Service, Hospital Nacional Edgardo Rebagliati Martins, EsSalud, Lima, Peru.
authors.forename: Fernando
authors.initials: F
authors.lastname: Mendo-Urbina
authors.affiliation: Research Group Public Health and Infection, Faculty of Health Sciences, Universidad Tecnológica de Pereira (UTP), Pereira, Risaralda, Colombia.
authors.forename: Alfonso J
authors.initials: AJ
authors.lastname: Rodríguez-Morales
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000209:etiology*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006760:Hospitalization; D006769:Hospitals, General; D006801:Humans; D008297:Male; D008875:Middle Aged; D010568:Peru; D012307:Risk Factors
keywords: Acquired Immunodeficiency Syndrome; Cardiovascular diseases; HIV; Peru