title: Surgical resection of solid gallbladder adenocarcinoma presenting as a large mass: report of a case.
abstract: This report describes a case of a patient with a large solid gallbladder adenocarcinoma that was completely resected through aggressive surgery. The patient was a 57-year-old woman who had been diagnosed with advanced gallbladder cancer, had no indications for surgical resection and was scheduled to undergo systemic chemotherapy. She presented to our hospital for a second opinion. At the time of assessment, her tumor was large but was well-localized and had not invaded into the surrounding tissues, indicating that surgical resection was a reasonable option. Subsequently, the tumor was completely extracted via right hepatectomy with en bloc resection of the caudate lobe and extrahepatic bile duct. Histopathologically, the tumor was a solid adenocarcinoma. Although there are relatively few reports in the literature regarding solid gallbladder adenocarcinoma, well-localized growth appears to be a characteristic feature. On the basis of a tumor's progression behavior, aggressive surgical treatment might be indicated even when the tumor has grown to a considerable size.
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. s-hayama@par.odn.ne.jp.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hayama
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. satto@msa.biglobe.ne.jp.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hirano
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. 310nonto@gmail.com.
authors.forename: Nagato
authors.initials: N
authors.lastname: Sato
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. yuma-ebi@wc4.so-net.ne.jp.
authors.forename: Yuma
authors.initials: Y
authors.lastname: Ebihara
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. yo.kurashima@gmail.com.
authors.forename: Yo
authors.initials: Y
authors.lastname: Kurashima
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. so-ichi@umin.ac.jp.
authors.forename: Soichi
authors.initials: S
authors.lastname: Murakami
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. etamoto1970@yahoo.co.jp.
authors.forename: Eiji
authors.initials: E
authors.lastname: Tamoto
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. torunakamura@med.hokudai.ac.jp.
authors.forename: Toru
authors.initials: T
authors.lastname: Nakamura
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. joematsumoto@med.hokudai.ac.jp.
authors.forename: Joe
authors.initials: J
authors.lastname: Matsumoto
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. tsuchi0108@gmail.com.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsuchikawa
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. etanaka36@gmail.com.
authors.forename: Eiichi
authors.initials: E
authors.lastname: Tanaka
authors.affiliation: Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15, W-7, Kita-ku, Sapporo, Hokkaido, 085-8512, Japan. shichino@med.hokudai.ac.jp.
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Shichinohe
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery*; D005260:Female; D005706:Gallbladder Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D011379:Prognosis