title: Evaluation of blood pressure control in an obstructive sleep apnea population followed in cardiology.
abstract: OBJECTIVE
  Obstructive sleep apnea (OSA) is the most common factor involved in uncontrolled blood pressure (BP). Management of OSA is part of cardiologist work. We have few data on BP control in a population of OSA followed by cardiologists.
  
  
  OBJECTIVE
  We evaluated the prevalence of effective BP control using ambulatory measurement in a population of patients followed in cardiology.
  
  
  METHODS
  Data from 69 OSA patients treated for more than 6 months by continuous positive airway pressure (CPAP) were collected prospectively from March 2012 until December 2012. These patients were divided into 2 groups according to the results of 24-h ambulatory BP monitoring (ABPM). Controlled BP was defined as a 24 h BP <130/80 mmHg.
  
  
  RESULTS
  All patients were hypertensive. 44 patients (63 %) had uncontrolled hypertension (HTN). The onset of OSA (p = 0.01) and persistent daytime sleepiness appeared as predictors of uncontrolled BP. Systolic BP (SBP) during consultation and all the ABPM variables were higher in uncontrolled BP patients. Uncontrolled BP was associated with greater left ventricular mass (p = 0.02) and greater diameter of the ascending aorta (p = 0.04).
  
  
  CONCLUSIONS
  Control of HTN should be evaluated in all OSA patients, using ABPM. The onset of OSA and high SBP during consultation are both factors associated with uncontrolled BP in this population. Repeating ABPM should be of interest for the follow up of these patients.
authors.affiliation: Service de médecine vasculaire et Hypertension artérielle, Hôpital Cardiologique, CHRU Lille, Boulevard Pr Leclercq, 59037, Lille Cedex, France, Pascal.DELSART@chru-lille.fr.
authors.forename: Pascal
authors.initials: P
authors.lastname: Delsart
authors.forename: Marc
authors.initials: M
authors.lastname: Takla
authors.forename: Philippe
authors.initials: P
authors.lastname: Marboeuf
authors.forename: Gonzague
authors.initials: G
authors.lastname: Claisse
authors.forename: Natalia
authors.initials: N
authors.lastname: Kpogbemabou
authors.forename: Remy
authors.initials: R
authors.lastname: Lubret
authors.forename: Medhi
authors.initials: M
authors.lastname: Hattabi
authors.forename: Claire
authors.initials: C
authors.lastname: Mounier-Vehier
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects*; D018660:Blood Pressure Monitoring, Ambulatory; D002309:Cardiology / Q000379:methods*; D045422:Continuous Positive Airway Pressure; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012890:Sleep; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents