title: Validation of a novel microradiography device for characterization of bone mineralization.
abstract: In order to simplify bone mineralization measurements, a system using radiographic films has been updated with a digital detector. The objective of this paper was to validate this new device. Technologies and physical phenomena involved in both systems (radiographic films and digital detector) are different. The methodology used to compare the two systems was based on image quality and assessed on two main parameters: contrast to noise ratio and spatial resolution. Results showed that the contrast to noise ratio was similar between the two systems, provided that acquisition parameters were optimized. With regard to spatial resolution, a magnification factor of at least 4 or more was required to achieve the same resolution as films. A final validation was also shown on a real image of a bone sample. The results showed that both systems have similar image quality performances, and the system using digital detector has several advantages (easier to use than films, no consumables and faster acquisition time).
authors.affiliation: INSERM, Lyon, France Université de Lyon, Lyon, France.
authors.forename: Florian
authors.initials: F
authors.lastname: Montagner
authors.affiliation: Laboratoire Vibrations Acoustique LVA, INSA-Lyon, Villeurbanne Cedex, France.
authors.forename: Valérie
authors.initials: V
authors.lastname: Kaftandjian
authors.affiliation: INSERM, Lyon, France Université de Lyon, Lyon, France.
authors.forename: Delphine
authors.initials: D
authors.lastname: Farlay
authors.affiliation: Photonic Science, St Etienne de St Geoirs, France.
authors.forename: Daniel
authors.initials: D
authors.lastname: Brau
authors.affiliation: INSERM, Lyon, France Université de Lyon, Lyon, France.
authors.forename: Georges
authors.initials: G
authors.lastname: Boivin
authors.affiliation: INSERM, Lyon, France Université de Lyon, Lyon, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Follet
mesh_terms: D002113:Calcification, Physiologic / Q000502:physiology*; D006801:Humans; D007085:Ilium / Q000000981:diagnostic imaging; D008852:Microradiography / Q000295:instrumentation* / Q000379:methods*; D015203:Reproducibility of Results; D012815:Signal Processing, Computer-Assisted
keywords: Mineralization of bone; contrast to noise ratio; digital detector; quantitative microradiography; spatial resolution