title: Synthesis of 2-(1,2,4-oxadiazol-3-yl)quinazolin-4(3H)-ones from diaminoglyoxime-based nitrones.
abstract: Various 2-[5-(aryl)-1,2,4-oxadiazol-3-yl]quinazolin-4(3H)-ones have been synthesized from the reaction of diaminoglyoxime-based nitrones with methyl 2-aminobenzoate or 2-aminobenzamide in the presence of acetic acid at 100 °C. The reaction was extended as a one-pot three-component approach starting from diaminoglyoxime, aldehyde and methyl 2-aminobenzoate.
authors.affiliation: Department of Chemistry, Faculty of Science, Imam Hossein University, Tehran, Iran.
authors.forename: Rahim
authors.initials: R
authors.lastname: Hosseinzadeh-Khanmiri
authors.forename: Abolghasem
authors.initials: A
authors.lastname: Moghimi
authors.forename: Ahmad
authors.initials: A
authors.lastname: Shaabani
authors.forename: Hassan
authors.initials: H
authors.lastname: Valizadeh
authors.forename: Seik Weng
authors.initials: SW
authors.lastname: Ng
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D062365:Aminobenzoates / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic; D008958:Models, Molecular; D008968:Molecular Conformation; D009589:Nitrogen Oxides / Q000737:chemistry*; D010091:Oximes / Q000737:chemistry*; D052999:Quinazolinones / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D062365:Aminobenzoates; D009589:Nitrogen Oxides; D010091:Oximes; D052999:Quinazolinones; C507900:diaminoglyoxime; C015388:nitrones