title: Blood, sweat, and tears: developing clinically relevant protein biosensors for integrated body fluid analysis.
abstract: Biosensors are being developed to provide rapid, quantitative, diagnostic information to clinicians in order to help guide patient treatment, without the need for centralised laboratory assays. The success of glucose monitoring is a key example of where technology innovation has met a clinical need at multiple levels – from the pathology laboratory all the way to the patient's home. However, few other biosensor devices are currently in routine use. Here we review the challenges and opportunities regarding the integration of biosensor techniques into body fluid sampling approaches, with emphasis on the point-of-care setting.
authors.affiliation: The University of Queensland, Australian Institute for Bioengineering and Nanotechnology, Delivery of Drugs and Genes Group (D2G2), St Lucia, Queensland 4072, Australia. s.corrie1@uq.edu.au.
authors.forename: S R
authors.initials: SR
authors.lastname: Corrie
authors.forename: J W
authors.initials: JW
authors.lastname: Coffey
authors.forename: J
authors.initials: J
authors.lastname: Islam
authors.forename: K A
authors.initials: KA
authors.lastname: Markey
authors.forename: M A F
authors.initials: MA
authors.lastname: Kendall
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000379:methods* / Q000639:trends*; D001826:Body Fluids / Q000737:chemistry*; D006801:Humans; D011506:Proteins / Q000737:chemistry*; D013542:Sweat / Q000737:chemistry; D013666:Tears / Q000737:chemistry
chemical_list: D011506:Proteins