title: Exercise and Estrogen Make Fat Cells "Fit".
abstract: Adipose tissue inflammation links obesity and metabolic disease. Both exercise and estrogen improve metabolic health, enhance mitochondrial function, and have antiinflammatory effects. We hypothesize that there is an inverse relationship between mitochondrial function and inflammation in adipose tissue and that exercise acts as an estrogen "mimetic." Explicitly, exercise may improve adipose tissue "immunometabolism" by improving mitochondrial function and reducing inflammation.
authors.affiliation: 1Departments of Nutrition and Exercise Physiology, and 2Child Health, and 3Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO.
authors.forename: Victoria J
authors.initials: VJ
authors.lastname: Vieira-Potter
authors.forename: Terese M
authors.initials: TM
authors.lastname: Zidon
authors.forename: Jaume
authors.initials: J
authors.lastname: Padilla
mesh_terms: D052436:Adipose Tissue, White / Q000502:physiology*; D004734:Energy Metabolism; D004967:Estrogens / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D008297:Male; D008928:Mitochondria / Q000502:physiology; D012737:Sex Factors
chemical_list: D004967:Estrogens