title: Responsive Double Network Hydrogels of Interpenetrating DNA and CB[8] Host-Guest Supramolecular Systems.
abstract: A supramolecular double network hydrogel is presented by physical interpenetration of DNA and cucurbit[8]uril networks. In addition to exhibiting an increase in strength and thermal stability, the double network hydrogel possesses excellent properties such as stretchability, ductility, shear-thinning, and thixotropy. Moreover, it is enzymatically responsive to both nuclease and cellulase, as well as small molecules, showing great potential as a new soft material scaffold.
authors.affiliation: Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
authors.forename: Chuang
authors.initials: C
authors.lastname: Li
authors.affiliation: Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK.
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Rowland
authors.affiliation: Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Shao
authors.affiliation: Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
authors.forename: Tianyang
authors.initials: T
authors.lastname: Cao
authors.affiliation: Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Chen
authors.affiliation: Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
authors.forename: Haoyang
authors.initials: H
authors.lastname: Jia
authors.affiliation: Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
authors.forename: Zhongqiang
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK.
authors.forename: Oren A
authors.initials: OA
authors.lastname: Scherman
authors.affiliation: Key Laboratory of Organic Optoelectronics and Molecular Engineering of the Ministry of Education, Department of Chemistry, Tsinghua University, Beijing, 100084, China.
authors.forename: Dongsheng
authors.initials: D
authors.lastname: Liu
mesh_terms: D001952:Bridged-Ring Compounds / Q000737:chemistry*; D002480:Cellulase / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D003851:Deoxyribonucleases / Q000737:chemistry; D020100:Hydrogels / Q000737:chemistry*; D021621:Imaging, Three-Dimensional; D007093:Imidazoles / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D010649:Phenylalanine / Q000737:chemistry; D012212:Rheology; D013696:Temperature; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
chemical_list: D001952:Bridged-Ring Compounds; D002480:Cellulase; D004247:DNA; D003851:Deoxyribonucleases; D020100:Hydrogels; D007093:Imidazoles; D010649:Phenylalanine; C507198:cucurbit(8)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
keywords: CB[8]; DNA; hydrogels; stimuli responsive; supramolecular double networks