title: Pathologic Changes in Wild Birds Infected with Highly Pathogenic Avian Influenza A(H5N8) Viruses, South Korea, 2014.
abstract: In January 2014, an outbreak of infection with highly pathogenic avian influenza (HPAI) A(H5N8) virus began on a duck farm in South Korea and spread to other poultry farms nearby. During this outbreak, many sick or dead wild birds were found around habitats frequented by migratory birds. To determine the causes of death, we examined 771 wild bird carcasses and identified HPAI A(H5N8) virus in 167. Gross and histologic lesions were observed in pancreas, lung, brain, and kidney of Baikal teals, bean geese, and whooper swans but not mallard ducks. Such lesions are consistent with lethal HPAI A(H5N8) virus infection. However, some HPAI-positive birds had died of gunshot wounds, peritonitis, or agrochemical poisoning rather than virus infection. These findings suggest that susceptibility to HPAI A(H5N8) virus varies among species of migratory birds and that asymptomatic migratory birds could be carriers of this virus.
authors.forename: Hye-Ryoung
authors.initials: HR
authors.lastname: Kim
authors.forename: Yong-Kuk
authors.initials: YK
authors.lastname: Kwon
authors.forename: Il
authors.initials: I
authors.lastname: Jang
authors.forename: Youn-Jeong
authors.initials: YJ
authors.lastname: Lee
authors.forename: Hyun-Mi
authors.initials: HM
authors.lastname: Kang
authors.forename: Eun-Kyoung
authors.initials: EK
authors.lastname: Lee
authors.forename: Byung-Min
authors.initials: BM
authors.lastname: Song
authors.forename: Hee-Soo
authors.initials: HS
authors.lastname: Lee
authors.forename: Yi-Seok
authors.initials: YS
authors.lastname: Joo
authors.forename: Kyung-Hyun
authors.initials: KH
authors.lastname: Lee
authors.forename: Hyun-Kyoung
authors.initials: HK
authors.lastname: Lee
authors.forename: Kang-Hyun
authors.initials: KH
authors.lastname: Baek
authors.forename: You-Chan
authors.initials: YC
authors.lastname: Bae
mesh_terms: D000818:Animals; D000835:Animals, Wild; D001717:Birds; D004196:Disease Outbreaks; D005838:Genotype; D049674:History, 21st Century; D009980:Influenza A virus / Q000145:classification* / Q000235:genetics* / Q000472:pathogenicity; D005585:Influenza in Birds / Q000175:diagnosis / Q000453:epidemiology* / Q000266:history / Q000821:virology*; D056910:Republic of Korea / Q000453:epidemiology
keywords: H5N8 subtype; South Korea; highly pathogenic avian influenza; immunohistochemistry; influenza; migratory bird; pathological diagnosis; respiratory infections; viruses