title: Protein interactions with corroding metal surfaces: comparison of Mg and Fe.
abstract: The influence of bovine serum albumin (BSA) on the electrochemical behaviour of pure Mg and Fe was studied in simulated body fluid (SBF), in view of the possible application of these materials as biodegradable metals. Results indicate a different trend for the BSA-effect on corrosion for the two metals: for Mg, a strong corrosion-inhibiting effect is observed in the presence of BSA in solution, especially for short-term exposure, whereas for Fe only a slight acceleration of corrosion is caused by the addition of BSA to the solution. For both metals, the protein-effect on the electrochemical behaviour shows a complex time-dependence. Surface analysis indicates that stronger BSA adsorption takes place on Mg than on Fe. Moreover, adsorption experiments with BSA and a second protein (lysozyme) were conducted. The results are discussed in view of electrostatic interactions between differently charged metal oxide/hydroxide surfaces and proteins.
authors.affiliation: Institute for Surface Science and Corrosion, University of Erlangen-Nuremberg, Martensstrasse 7 (WW4, LKO), 91058 Erlangen, Germany. virtanen@ww.uni-erlangen.de.
authors.forename: Victoria
authors.initials: V
authors.lastname: Wagener
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Faltz
authors.forename: Manuela S
authors.initials: MS
authors.lastname: Killian
authors.forename: Patrik
authors.initials: P
authors.lastname: Schmuki
authors.forename: Sannakaisa
authors.initials: S
authors.lastname: Virtanen
mesh_terms: D000818:Animals; D002417:Cattle; D003343:Corrosion; D004563:Electrochemistry; D007501:Iron / Q000737:chemistry*; D008274:Magnesium / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D055672:Static Electricity
chemical_list: D012710:Serum Albumin, Bovine; D007501:Iron; D008274:Magnesium