title: [Role of viruses with oncogenic potential and their associations in oncogenesis in maxillofacial area].
abstract: The potential role of viruses with oncogenic potential such as human papilloma virus, cytomegalovirus, Epstein-Barr virus, herpes simplex virus type 1 and 2, herpes virus type 6, in the development of benign and pre-cancerous tumors of maxillofacial region was assessed in the study. We examined 26 patients with tumors in maxillofacial region (skin and mucosa) using molecular-genetic and histological studies of surgically removed neoplasms removed. In 53.8% of the examined samples DNA of Epstein-Barr virus, herpes virus type 6, herpes simplex virus type 1, or cytomegalovirus and in 35.7% of them the association of the above mentioned viruses were detected. It may confirm their relation with the development of benign, precancerous and malignant neoplasms in maxillofacial region.
authors.affiliation: Tverskaia gosudarstvennaia meditsinskaia akademiia Minzdrava Rossii, 170000, Tver', Rossiia.
authors.forename: V V
authors.initials: VV
authors.lastname: Bogatov
authors.affiliation: Tverskaia gosudarstvennaia meditsinskaia akademiia Minzdrava Rossii, 170000, Tver', Rossiia.
authors.forename: V M
authors.initials: VM
authors.lastname: Chervinets
authors.affiliation: Tverskaia gosudarstvennaia meditsinskaia akademiia Minzdrava Rossii, 170000, Tver', Rossiia.
authors.forename: A M
authors.initials: AM
authors.lastname: Samoukina
authors.affiliation: Tverskaia gosudarstvennaia meditsinskaia akademiia Minzdrava Rossii, 170000, Tver', Rossiia.
authors.forename: S N
authors.initials: SN
authors.lastname: Lebedev
authors.affiliation: Tverskaia gosudarstvennaia meditsinskaia akademiia Minzdrava Rossii, 170000, Tver', Rossiia.
authors.forename: M V
authors.initials: MV
authors.lastname: Nasonova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002472:Cell Transformation, Viral; D004279:DNA, Viral / Q000302:isolation & purification; D005153:Facial Neoplasms / Q000821:virology*; D005260:Female; D006801:Humans; D008297:Male; D008441:Maxillary Neoplasms / Q000821:virology*; D008875:Middle Aged; D009858:Oncogenic Viruses / Q000302:isolation & purification / Q000502:physiology*; D011230:Precancerous Conditions / Q000821:virology*; D012878:Skin Neoplasms / Q000821:virology*; D055815:Young Adult
chemical_list: D004279:DNA, Viral