title: A concise review on extracorporeal photochemotherapy: Where we began and where we are now and where are we going!
abstract: Currently, more than 1080 peer-reviewed papers are displayed on PubMed when initiating a search for therapeutic indications and mechanisms of action of extracorporeal photochemotherapy (ECP). This concise review focuses mainly on some prevalent and traditional treatment-resistant disorders with an emphasis on immunologic complications emerging from stem cell and solid organ transplantation.
authors.affiliation: Therapeutic Apheresis and Stem Cell Manipulation, Immunohematology Service, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. Electronic address: c.perotti@smatteo.pv.it.
authors.forename: Cesare
authors.initials: C
authors.lastname: Perotti
authors.affiliation: Department of Transfusion Medicine and Member-Physician, Division of Hematology and BMT, City of Hope National Research Institute, Duarte, CA, USA.
authors.forename: Irena
authors.initials: I
authors.lastname: Sniecinski
mesh_terms: D000208:Acute Disease; D000818:Animals; D001781:Blood Component Removal / Q000379:methods; D006086:Graft vs Host Disease / Q000517:prevention & control / Q000628:therapy; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000628:therapy; D016377:Organ Transplantation / Q000009:adverse effects; D017893:Photopheresis / Q000266:history / Q000379:methods* / Q000639:trends*; D014184:Transplantation, Homologous
keywords: Allogeneic hematopoietic cell transplantation; Apheresis techniques and systems; Existing guidelines; Extracorporeal photopheresis; Graft versus host disease; Immunomodulation; Organ transplantation