title: Effect of sub-lethal concentration of endosulfan on lipid and fatty acid metabolism of spotted murrel, Channa punctatus.
abstract: The spotted murrel, Channa punctatuswere exposed to sub-lethal concentration of endosulfan (8.1 microg l(-1)) for 12, 24, 48, 72 and 96 hrto elucidate the impact of pesticide on fatty acid composition of liver and muscle. After endosulfan exposure, fish from each control and experimental tanks were randomly sampled anesthetized, sacrificed and then the liver and muscle were dissected out for lipid and fatty acid (FA) profile. Results showed that total lipid, cholesterol, and triglyceride and FA in liver and muscle, and phospholipid in liver were significantly affected due to pesticide exposure. In liver and muscle tissues, 28.09 and 32.57% reduction of the total lipid, and 42.82 and 49.75% reduction in triglyceride and FAwere observed at the end of 96 hrs of exposure. Reduction of total lipid, triglyceride and FA may be due to their mobilization for energy production to combat stress. In FA, oleic (25.46 to 22.48% in liver and 25.75 to 21.87% in muscle) and linoleic acids (8.04 to 6.83% in liver and 9.88 to 8.09%) were reduced in both the tissues at the end of 96 hr of exposure. It may be concluded that exposure of fish to sub-lethal concentration of endosulfan had influenced the lipid and fatty acid metabolism of Channa punctatus.
authors.forename: Kamal
authors.initials: K
authors.lastname: Sarma
authors.forename: A K
authors.initials: AK
authors.lastname: Pal
authors.lastname: Grinson-George
authors.forename: Kartik
authors.initials: K
authors.lastname: Baruah
mesh_terms: D000818:Animals; D004726:Endosulfan / Q000008:administration & dosage / Q000633:toxicity*; D005227:Fatty Acids / Q000378:metabolism*; D005399:Fishes / Q000378:metabolism*; D050356:Lipid Metabolism / Q000187:drug effects*; D008099:Liver / Q000378:metabolism; D018482:Muscle, Skeletal / Q000378:metabolism; D014874:Water Pollutants, Chemical / Q000008:administration & dosage / Q000633:toxicity*
chemical_list: D005227:Fatty Acids; D014874:Water Pollutants, Chemical; D004726:Endosulfan