title: Histological Evaluation of Allium sativum Oil as a New Medicament for Pulp Treatment of Permanent Teeth.
abstract: The objective of this study was to evaluate the histo pathology effects of two medicaments Allium sativum oil and formocresol on the remaining pulp tissue of the permanent teething children.
  
  
  
  A total of 18 premolars were included in this study. Two sound premolars were extracted and subjected to histological examination to show the normal pulp tissue. Pulpo tomy procedure was performed in the rest of the remaining 16 premolars; half of them using Allium sativum oil and the rest of the tested premolars were medicated using formocresol and all were sealed with suitable restoration. Then, premolars extracted at variable intervals (48 hours, 2 weeks, 1 month, 2 months), stained using hemotoxylin and eosin etain (H&E) and prepared for histopathology examination.
  
  
  
  Histological evaluation seemed far more promising for Allium sativum oil than formocresol. Histological evaluation revealed that teeth treated with Allium sativa oil showed infammatory changes that had been resolved in the end of the study. On the contrary, the severe chronic infammation of pulp tissue accompanied with formocresol eventually produced pulp necrosis with or without fibrosis. In addition, pulp calcification was evidenced in certain cases.
  
  
  
  Allium sativum oil is a biocompatible material that is compatible with vital human pulp tissue. It offers a good healing potential, leaving the remaining pulp tissue healthy and functioning.
authors.affiliation: Department of Restorative Dental Sciences, Al-Farabi College, Riyadh, Saudi Arabia; Department of Pediatric Dentistry, School of Dentistry, Al-Azhar University, Egypt.
authors.forename: Shukry Gamal
authors.initials: SG
authors.lastname: Mohammad
authors.affiliation: Department of Oral and Maxillofacial Sciences, Al-Farabi College of Dentistry and Nursing, Riyadh, Saudi Arabia.
authors.forename: Syed Ahmed
authors.initials: SA
authors.lastname: Raheel
authors.affiliation: Assistant Professor, Department of Restorative Dental Sciences, Al-Farabi College of Dentistry and Nursing, Riyadh, Saudi Arabia, Riyadh-11691, PO Box: 85184, Fax: +96612324580, Phone 00966-12273151, e-mail: d_kusai@yahoo.co.uk.
authors.forename: Kusai
authors.initials: K
authors.lastname: Baroudi
mesh_terms: D000293:Adolescent; D000498:Allyl Compounds / Q000627:therapeutic use*; D001641:Bicuspid / Q000187:drug effects / Q000473:pathology; D003782:Dental Pulp / Q000187:drug effects* / Q000473:pathology; D003784:Dental Pulp Calcification / Q000473:pathology; D003790:Dental Pulp Necrosis / Q000473:pathology; D003804:Dentin / Q000187:drug effects / Q000473:pathology; D004487:Edema / Q000473:pathology; D005260:Female; D005355:Fibrosis; D005500:Follow-Up Studies; D005566:Formocresols / Q000627:therapeutic use; D005737:Garlic; D006801:Humans; D006940:Hyperemia / Q000473:pathology; D008297:Male; D009804:Odontoblasts / Q000473:pathology; D008517:Phytotherapy / Q000379:methods; D010938:Plant Oils / Q000627:therapeutic use*; D011671:Pulpitis / Q000473:pathology; D011672:Pulpotomy / Q000379:methods*; D013440:Sulfides / Q000627:therapeutic use*
chemical_list: D000498:Allyl Compounds; D005566:Formocresols; D010938:Plant Oils; D013440:Sulfides; C031025:formocresol; C038491:allyl sulfide
keywords: Allium sativum oil; Formocresol; Pulpotomy.