title: Risk factors for infection with Escherichia coli in nursing home residents colonized with fluoroquinolone-resistant E. coli.
abstract: A case-control study to determine risk factors for clinical infection with Escherichia coli was conducted among nursing home residents colonized with fluoroquinolone-resistant E. coli. Among 94 subjects, 11 (12%) developed infections with E. coli. Risk factors included the presence of a urinary catheter or tracheostomy, diabetes mellitus, and trimethoprim-sulfamethoxazole exposure.
authors.affiliation: 1Perelman School of Medicine,University of Pennsylvania,Philadelphia,Pennsylvania.
authors.forename: Sara
authors.initials: S
authors.lastname: Manning
authors.affiliation: 2Division of Infectious Diseases,Department of Medicine,University of Pennsylvania,Philadelphia,Pennsylvania.
authors.forename: Ebbing
authors.initials: E
authors.lastname: Lautenbach
authors.affiliation: 3Center for Clinical Epidemiology and Biostatistics,University of Pennsylvania,Philadelphia,Pennsylvania.
authors.forename: Pam
authors.initials: P
authors.lastname: Tolomeo
authors.affiliation: 2Division of Infectious Diseases,Department of Medicine,University of Pennsylvania,Philadelphia,Pennsylvania.
authors.forename: Jennifer H
authors.initials: JH
authors.lastname: Han
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016022:Case-Control Studies; D003428:Cross Infection / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D048909:Diabetes Complications / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects*; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D024841:Fluoroquinolones / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009735:Nursing Homes / Q000706:statistics & numerical data*; D012307:Risk Factors; D014139:Tracheostomy / Q000009:adverse effects; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects / Q000627:therapeutic use; D062885:Urinary Catheters / Q000009:adverse effects
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D015662:Trimethoprim, Sulfamethoxazole Drug Combination