title: Treatments for Hypertension in Type 2 Diabetes-Non-pharmacological and Pharmacological Measurements.
abstract: Obesity, hypertension, obesity-related hypertension such as hypertension with diabetes are growing health problems. Obesity, hypertension and diabetes are important, independent risk factors for the onset and development of cardiovascular diseases. Hypertension in obesity is characterized by stimulation of the renin-angiotensin-aldosterone system (RAAS), elevated sympathetic activity, insulin resistance and selective leptin resistance. It is known that these characteristics, even in isolation, constitute risk factors for cardiovascular disease onset and progression. Therefore, pharmacological treatments should be selected based on favourable effects on insulin resistance, stimulated RAAS and sympathetic nervous systems.
authors.affiliation: Nucleus Network Ltd. and Human Neurotransmitters Laboratory, Baker IDI Heart & Diabetes Institute, 89 Commercial Road, Melbourne, Victoria 3004, Australia. kazuko.masuo@bakeridi.edu.au.
authors.forename: Kazuko
authors.initials: K
authors.lastname: Masuo
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D047228:Angiotensin II Type 1 Receptor Blockers / Q000627:therapeutic use; D050110:Bariatric Surgery; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D031204:Caloric Restriction; D003714:Denervation; D003925:Diabetic Angiopathies / Q000188:drug therapy / Q000453:epidemiology / Q000628:therapy*; D015438:Health Behavior; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology / Q000628:therapy*; D007333:Insulin Resistance / Q000502:physiology; D007668:Kidney / Q000294:innervation; D009765:Obesity / Q000453:epidemiology; D012084:Renin-Angiotensin System / Q000187:drug effects / Q000502:physiology; D012307:Risk Factors; D040242:Risk Reduction Behavior; D015431:Weight Loss / Q000502:physiology
chemical_list: D000319:Adrenergic beta-Antagonists; D047228:Angiotensin II Type 1 Receptor Blockers; D002121:Calcium Channel Blockers