title: NUT Midline Carcinoma in Elderly Patients: Usefulness of 18F-FDG PET/CT for Treatment Assessment.
abstract: Nuclear protein in testis (NUT) midline carcinoma is a rare disease that generally arises in adolescents and young adults. However, we encountered a rare NUT midline carcinoma case in an elderly patient. F-2-fluoro-2-deoxyglucose positron emission tomography/computed tomography (PET/CT) studies were performed before and during the treatment course. In this case, the initial PET/CT study revealed locoregional hypermetabolism in the mediastinal lesion. After then, the interim PET/CT study indicated a clear diminishing response to the initial treatment, whereas the residual masses were morphologically observable. Nuclear imaging may allow visualization of the therapeutic effect of antineoplastic therapies in both young and elderly patients.
authors.affiliation: From the *Department of Radiation Oncology; †Department of Respiratory Medicine; and ‡Division of Nuclear Medicine, Department of Radiology, National Center for Global Health and Medicine, Toyama, Shinjuku-ku, Tokyo, Japan.
authors.forename: Takatsugu
authors.initials: T
authors.lastname: Kawase
authors.forename: Go
authors.initials: G
authors.lastname: Naka
authors.forename: Kazuo
authors.initials: K
authors.lastname: Kubota
authors.forename: Baku
authors.initials: B
authors.lastname: Sakashita
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Takeda
mesh_terms: D002277:Carcinoma / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18