title: The endometrium as a source of mesenchymal stem cells for regenerative medicine.
abstract: Stem cell therapies have opened new frontiers in medicine with the possibility of regenerating lost or damaged cells. Embryonic stem cells, induced pluripotent stem cells, hematopoietic stem cells, and mesenchymal stem cells have been used to derive mature cell types for tissue regeneration and repair. However, the endometrium has emerged as an attractive, novel source of adult stem cells that are easily accessed and demonstrate remarkable differentiation capacity. In this review, we summarize our current understanding of endometrial stem cells and their therapeutic potential in regenerative medicine.
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut.
authors.forename: Levent
authors.initials: L
authors.lastname: Mutlu
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut.
authors.forename: Demetra
authors.initials: D
authors.lastname: Hufnagel
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut hugh.taylor@yale.edu.
authors.forename: Hugh S
authors.initials: HS
authors.lastname: Taylor
mesh_terms: D004717:Endometrium / Q000166:cytology*; D005260:Female; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods*; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D044968:Regenerative Medicine; D014945:Wound Healing
keywords: cell transplantation; endometrium; mesenchymal stem cells; regenerative medicine; stem cells