title: Morphofunctional adaptation of rat thymus structures to silicon consumption with drinking water.
abstract: Administration of standardized drinking water containing 10 mg/liter silicon for 2 months adlibitum induced structural reorganization of the cortical and medullary layers of the thymiclobules in laboratory rats accompanied by functional activation of monocyte/macrophage cells and antigen-presenting cells was changed in morphological structures of the thymus. A possible mechanism of development of autoimmune processes under the effect of silicon is discussed.
authors.affiliation: I. N. Ul'yanov Chuvash State University, Cheboksary, Russia, crataegi@rambler.ru.
authors.forename: V S
authors.initials: VS
authors.lastname: Gordova
authors.forename: I M
authors.initials: IM
authors.lastname: Dyachkova
authors.forename: V E
authors.initials: VE
authors.lastname: Sergeeva
authors.forename: S P
authors.initials: SP
authors.lastname: Sapozhnikov
authors.forename: A T
authors.initials: AT
authors.lastname: Smorodchenko
mesh_terms: D000222:Adaptation, Physiological / Q000187:drug effects; D000818:Animals; D060766:Drinking Water / Q000009:adverse effects*; D008297:Male; D051381:Rats; D012825:Silicon / Q000009:adverse effects*; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects*
chemical_list: D060766:Drinking Water; D012825:Silicon