title: Rhomboid proteases in invasion and replication of Apicomplexa.
abstract: In this issue of Molecular Microbiology, Rugarabamu and colleagues investigate the role of rhomboid proteases responsible for adhesin shedding during invasion of the apicomplexan parasite Toxoplasma gondii. This study, together with several other recent publications, raises new questions about the function of these rhomboids in Toxoplasma, while also strongly arguing against other recently proposed roles for these proteases.
authors.affiliation: Division of Infection and Immunity, The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.|The Department of Medical Biology, The University of Melbourne, Melbourne, Vic., Australia.
authors.forename: Rebecca J
authors.initials: RJ
authors.lastname: Stewart
authors.affiliation: Division of Infection and Immunity, The Walter and Eliza Hall Institute of Medical Research, Parkville, Vic., Australia.|The Department of Medical Biology, The University of Melbourne, Melbourne, Vic., Australia.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Tonkin
mesh_terms: D015815:Cell Adhesion Molecules / Q000378:metabolism*; D006801:Humans; D010447:Peptide Hydrolases / Q000378:metabolism*; D015800:Protozoan Proteins / Q000378:metabolism*; D014122:Toxoplasma / Q000201:enzymology* / Q000472:pathogenicity*
chemical_list: D015815:Cell Adhesion Molecules; D015800:Protozoan Proteins; D010447:Peptide Hydrolases