title: Staged urethroplasty: comparison of early functional results and quality of life in mesh graft and buccal mucosa technique.
abstract: BACKGROUND
  To assess bothersome results of surgery and changes in quality of life (QoL) in patients with two-staged urethral reconstruction. In patients requiring two-staged urethroplasty a functional corpus spongiosum is usually absent, and complications such as urinary dribbling, ejaculation problems and penile deviation can be expected. Data on these complications, patient satisfaction and QoL is limited.
  
  
  METHODS
  Retrospective analysis by chart review and a standardized questionnaire of 19 consecutive patients with urethral strictures treated by two-staged urethroplasty with buccal-mucosa-graft or mesh-graft.
  
  
  RESULTS
  Overall success rate was 84%. Mean follow up 11.2 months, mean length of graft 10 cm (3 cm-18 cm). Urinary stress incontinence occurred in 3 patients (16%). No penile shortening occurred in 9 (47%), no deviation in 11 (58%). Two patients (11%) reported a disturbing alteration in glans sensitivity. Regarding bother by both surgeries and the interval in between, 21% judged the first surgery as hardly or not bothersome. The time in between surgeries was hardly or not bothersome in 52% and the second surgery not or hardly bothersome in 26%. Overall satisfaction with surgery was high (79%) and an improvement in QoL was reported by 63%. Differences between the two groups did not reach statistical significance.
  
  
  CONCLUSIONS
  Two-staged urethroplasty is a viable therapeutic option in patients with severe spongiofibrosis. However, specific counseling for possible complications is of utmost importance.
authors.affiliation: University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Pfalzgraf
authors.forename: Luis
authors.initials: L
authors.lastname: Kluth
authors.forename: Philip
authors.initials: P
authors.lastname: Reiss
authors.forename: Margit
authors.initials: M
authors.lastname: Fisch
authors.forename: Roland
authors.initials: R
authors.lastname: Dahlem
mesh_terms: D000293:Adolescent; D000328:Adult; D007172:Erectile Dysfunction / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000637:transplantation*; D017060:Patient Satisfaction; D061686:Premature Ejaculation / Q000453:epidemiology; D011788:Quality of Life; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D013526:Surgical Mesh; D011795:Surveys and Questionnaires; D016378:Tissue Transplantation / Q000379:methods*; D016896:Treatment Outcome; D014521:Urethra / Q000503:physiopathology / Q000601:surgery*; D014525:Urethral Stricture / Q000503:physiopathology / Q000601:surgery*; D014550:Urinary Incontinence, Stress / Q000453:epidemiology; D013521:Urologic Surgical Procedures, Male / Q000379:methods*; D055815:Young Adult