title: Chest wall granuloma associated with BCG vaccination presenting as hot abscess in an immunocompetent infant.
abstract: Bacillus-Calmette-Gue´rin (BCG) vaccine is a live attenuated vaccine to prevent tuberculosis by cell mediated immune response and is routinely administered early after birth. Although it is considered to be a very safe vaccine, sometimes a variety of complications may develop. Herein we describe a clinically unusual case of chest wall granuloma considered to be induced by BCG, presenting as hot abscess, and developed 7 months after BCG vaccination in an immunocompetent infant. The diagnosis was made based on the history, histopathology and virological studies. We suggest, although very rare, a BCG disease should be considered as a differential diagnosis in case of chest wall abscess, even if this is presenting as a hot abscess and even in immunocompetent infants if their age is related to BCG vaccination complications.
authors.affiliation: Department of Pediatrics, Uijeongbu St. Mary's Hospital, The Catholic University of Korea College of Medicine, Uijeongbu, South Korea. iamlidia@catholic.ac.kr.
authors.forename: Hyun Seung
authors.initials: HS
authors.lastname: Lee
authors.affiliation: Pathology, Uijeongbu St. Mary's Hospital, The Catholic University of Korea College of Medicine, Uijeongbu, South Korea. ywacko@catholic.ac.kr.
authors.forename: Kyung Jin
authors.initials: KJ
authors.lastname: Seo
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Uijeongbu St. Mary's Hospital, The Catholic University of Korea College of Medicine, 271 Cheonbo Street, Uijeongbu City, Gyeonggi-do, 480-717, Korea. medkjj@hanmail.net.
authors.forename: Jae Jun
authors.initials: JJ
authors.lastname: Kim
mesh_terms: D000038:Abscess / Q000276:immunology / Q000382:microbiology*; D001500:BCG Vaccine / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D007121:Immunocompetence; D007223:Infant; D009163:Mycobacterium bovis; D035441:Thoracic Wall; D014376:Tuberculosis / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D014611:Vaccination / Q000009:adverse effects
chemical_list: D001500:BCG Vaccine