title: Bisphenol A contamination in soft drinks as a risk for children's health in Italy.
abstract: Bisphenol A (BPA) was determined in sugary carbonated, non-carbonated and milk-based beverages, through HLPC-fluorescence detection and confirmed by LC-MS/MS, in a selection of brands that are mostly consumed by Italian children. The daily intake was determined through the WHO budget method (BM). BPA was found at detectable levels in 57% of carbonated beverages, in 50% of non-carbonated and in 100% of milk-based beverages. The median concentrations were 1.24 µg l(-1) (range = < LOD-4.98 µg l(-1)) in canned carbonated beverages and 0.18 µg l(-1) (< LOD-1.78 µg l(-1)) in non-canned carbonated beverages. In non-carbonated beverages, median concentrations were 0.80 µg l(-1) (< LOD-2.79 µg l(-1)) and 0.18 µg l(-1) (< LOD-3.58 µg l(-1)), respectively, for canned and non-canned beverages; in milk-based products the BPA median concentration was 3.60 µg l(-1) (1.00-17.65 µg l(-1)). BPA daily intake from sugary drink consumption in children ranged from 0.008 to 1.765 µg kg(-1) bw day(-1). The median exposure values for the 'best' and 'worst' cases were 0.16% and 0.47% respectively of the EFSA t-TDI for BPA (4 µg kg(-1) bw day(-1)), and 10.59% and 35.30% of the t-TDI when the maximum levels were considered.
authors.affiliation: a Department of Agriculture , 'Federico II' University of Naples, Via Università , Portici, Naples , Italy.
authors.forename: Evelina
authors.initials: E
authors.lastname: Fasano
authors.forename: Francesco
authors.initials: F
authors.lastname: Esposito
authors.forename: Gelsomina
authors.initials: G
authors.lastname: Scognamiglio
authors.forename: Fabio
authors.initials: F
authors.lastname: Di Francesco
authors.forename: Paolo
authors.initials: P
authors.lastname: Montuori
authors.forename: Renata
authors.initials: R
authors.lastname: Amodio Cocchieri
authors.forename: Teresa
authors.initials: T
authors.lastname: Cirillo
mesh_terms: D001559:Benzhydryl Compounds / Q000737:chemistry* / Q000633:toxicity*; D002253:Carbonated Beverages / Q000032:analysis*; D002648:Child; D005506:Food Contamination / Q000032:analysis; D018857:Food Packaging; D006801:Humans; D007558:Italy; D010636:Phenols / Q000737:chemistry* / Q000633:toxicity*; D018570:Risk Assessment; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: BPA; chemical contamination; children’s intake; sugary beverages