title: Ventilatory function in young adults and dietary antioxidant intake.
abstract: Dietary antioxidants may protect against poor ventilatory function. We assessed the relation between ventilatory function and antioxidant components of diet in young Chileans. Forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), and the ratio FEV1/FVC were measured in 1232 adults aged 22-28 years, using a Vitalograph device. Dietary intake was ascertained with a food frequency questionnaire (FFQ) designed for this study, from which nutrient and flavonoid intakes were estimated. Dietary patterns were derived with Principal Component Analysis (PCA). After controlling for potential confounders, dietary intake of total catechins was positively associated with FVC (Regression coefficient (RC) of highest vs. lowest quintile of intake 0.07; 95% CI 0.01 to 0.15; p per trend 0.006). Total fruit intake was related to FVC (RC of highest vs. lowest quintile 0.08; 95% CI 0.003 to 0.15; p per trend 0.02). Intake of omega 3 fatty acids was associated with a higher FEV1 (RC for highest vs. lowest quintile 0.08; 95% CI 0.01 to 0.15 L; p per trend 0.02) and with FVC 0.08 (RC in highest vs. lowest quintile of intake 0.08, 95% CI 0.001 to 0.16; p per trend 0.04). Our results show that fresh fruits, flavonoids, and omega 3 fatty acids may contribute to maintain ventilatory function.
authors.affiliation: Respiratory Epidemiology, Occupational Medicine, and Public Health Group, National Heart & Lung Institute, Imperial College London, London, SW3 6LR, UK. v.garcialarsen@imperial.ac.uk.|Royal Brompton Hospital and Harefield NHS Foundation Trust, Sydney Street, London SW3 6NP, UK. v.garcialarsen@imperial.ac.uk.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Garcia-Larsen
authors.affiliation: Department of Nutrition, Faculty of Medicine, University of Chile, Independencia 1027, Santiago, Chile. hamigo@med.uchile.cl.
authors.forename: Hugo
authors.initials: H
authors.lastname: Amigo
authors.affiliation: Department of Nutrition, Faculty of Medicine, University of Chile, Independencia 1027, Santiago, Chile. pbustos@med.uchile.cl.
authors.forename: Patricia
authors.initials: P
authors.lastname: Bustos
authors.affiliation: MRC-HPA Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1NY, UK. i.bakolis@imperial.ac.uk.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Bakolis
authors.affiliation: Department of Psychological Medicine, Weston Education Centre, King's College, London, SE5 9RJ, UK. roberto.rona@kcl.ac.uk.
authors.forename: Roberto J
authors.initials: RJ
authors.lastname: Rona
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000008:administration & dosage*; D015992:Body Mass Index; D001835:Body Weight; D002392:Catechin / Q000008:administration & dosage; D002677:Chile; D003430:Cross-Sectional Studies; D002149:Energy Intake; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage; D005247:Feeding Behavior; D005260:Female; D005419:Flavonoids / Q000008:administration & dosage; D005541:Forced Expiratory Volume; D005638:Fruit; D006801:Humans; D008168:Lung / Q000502:physiology*; D008297:Male; D025341:Principal Component Analysis; D013147:Spirometry; D011795:Surveys and Questionnaires; D014797:Vital Capacity; D055815:Young Adult
chemical_list: D000975:Antioxidants; D015525:Fatty Acids, Omega-3; D005419:Flavonoids; D002392:Catechin