title: Perforated appendicitis after intravenous immunoglobulin therapy in a term neonate with haemolytic jaundice.
abstract: Neonatal appendicitis is a rare clinical condition that may cause high morbidity and mortality if diagnosis is delayed. There is usually an underlying disease; it can also be a localized form of necrotizing enterocolitis. Here, we present a term neonate who was treated with intravenous immunoglobulin because of severe isoimmune hemolytic jaundice. The patient developed abdominal symptoms within 10 hours of therapy, was diagnosed with acute perforated appendicitis and completely recovered after surgery.
authors.affiliation: Department of Pediatrics, Ege University, Faculty of Medicine, Izmir, Turkey.
authors.forename: Basak Yildiz
authors.initials: BY
authors.lastname: Atikan
authors.affiliation: Department of Pediatrics, Division of Neonatology, Ege University, Faculty of Medicine, Izmir, Turkey.
authors.forename: Ozge Altun
authors.initials: OA
authors.lastname: Koroglu
authors.affiliation: Department of Pediatrics, Division of Neonatology, Ege University, Faculty of Medicine, Izmir, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yalaz
authors.affiliation: Department of Pediatric Surgery, Ege University, Faculty of Medicine, Izmir, Turkey.
authors.forename: Orkan
authors.initials: O
authors.lastname: Ergun
authors.affiliation: Department of Pediatric Surgery, Ege University, Faculty of Medicine, Izmir, Turkey.
authors.forename: Zafer
authors.initials: Z
authors.lastname: Dokumcu
authors.affiliation: Department of Pathology, Ege University, Faculty of Medicine, Izmir, Turkey.
authors.forename: Basak
authors.initials: B
authors.lastname: Doganavsargil
authors.affiliation: Department of Pediatrics, Division of Neonatology, Ege University, Faculty of Medicine, Izmir, Turkey.
authors.forename: Mete
authors.initials: M
authors.lastname: Akisu
authors.affiliation: Department of Pediatrics, Division of Neonatology, Ege University, Faculty of Medicine, Izmir, Turkey.
authors.forename: Nilgun
authors.initials: N
authors.lastname: Kultursay
mesh_terms: D000208:Acute Disease; D001062:Appendectomy; D001064:Appendicitis / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects* / Q000627:therapeutic use; D007155:Immunologic Factors / Q000009:adverse effects / Q000627:therapeutic use; D007231:Infant, Newborn; D007416:Intestinal Perforation / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D007567:Jaundice, Neonatal / Q000188:drug therapy*; D007813:Laparotomy; D047929:Term Birth
chemical_list: D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors