title: Renal dysfunction in adults during measles.
abstract: BACKGROUND
  Many cases of measles in adults were notified during the epidemic in France in 2008. Studying these cases can lead to a better understanding of their potential complications, little data having been reported on renal dysfunction during measles.
  
  
  METHODS
  A retrospective study of biologically confirmed measles cases in patients hospitalized for more than 24 hours was carried out in the Nantes Teaching Hospital, between January and December 2011. The renal function was assessed using the modification of diet in renal disease (MDRD) equation.
  
  
  RESULTS
  Thirty-eight patients were included, 17 (45%) presented with a clearance below 90 mL/min. One patient presented with acute renal failure, with a clearance at 37 mL/min, and proteinuria at 2.8 g/L. His renal function was restored on day 2.
  
  
  CONCLUSIONS
  Acute renal failure can occur during measles in adults. Serum creatinine should be systematically assessed during the initial medical evaluation.
authors.affiliation: Service de maladies infectieuses et tropicales, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France. Electronic address: arianechassort@hotmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Chassort
authors.affiliation: Centre de vaccinations polyvalentes, CHU de Nantes, 5, rue du Pr-Yves-Boquien, 44093 Nantes cedex 1, France. Electronic address: julie.coutherut@chu-nantes.fr.
authors.forename: J
authors.initials: J
authors.lastname: Coutherut
authors.affiliation: Laboratoire de virologie, CHU de Nantes, quai Moncousu, 44093 Nantes cedex 1, France. Electronic address: anne.moreauklein@chu-nantes.fr.
authors.forename: A
authors.initials: A
authors.lastname: Moreau-Klein
authors.affiliation: Service de pédiatrie, CHU de Nantes, 7, quai Moncousu, 44093 Nantes cedex 1, France. Electronic address: christele.grasleguen@chu-nantes.fr.
authors.forename: C
authors.initials: C
authors.lastname: Gras-Le Guen
authors.affiliation: Pôle des urgences, CHU de Nantes, 9, quai Moncousu, 44093 Nantes cedex 1, France. Electronic address: david.trewick@chu-nantes.fr.
authors.forename: D
authors.initials: D
authors.lastname: Trewick
authors.affiliation: Service de maladies infectieuses et tropicales, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France. Electronic address: francois.raffi@chu-nantes.fr.
authors.forename: F
authors.initials: F
authors.lastname: Raffi
authors.affiliation: Service de maladies infectieuses et tropicales, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France; Centre de vaccinations polyvalentes, CHU de Nantes, 5, rue du Pr-Yves-Boquien, 44093 Nantes cedex 1, France. Electronic address: charlotte.biron@chu-nantes.fr.
authors.forename: C
authors.initials: C
authors.lastname: Biron
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D000293:Adolescent; D000328:Adult; D003404:Creatinine / Q000097:blood; D004196:Disease Outbreaks; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D007297:Inpatients; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D008457:Measles / Q000097:blood / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology*; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D051437:Renal Insufficiency / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D003404:Creatinine
keywords: Atteinte rénale; Measles; Renal dysfunction; Rougeole