title: Self-propelled carbon nanotube based microrockets for rapid capture and isolation of circulating tumor cells.
abstract: Here, we report a non-invasive strategy for isolating cancer cells by autonomously propelled carbon nanotube (CNT) microrockets. H2O2-driven oxygen (O2) bubble-propelled microrockets were synthesized using CNT and Fe3O4 nanoparticles in the inner surface and covalently conjugating transferrin on the outer surface. Results show that self-propellant microrockets can specifically capture cancer cells.
authors.affiliation: Actorius Innovations and Research (AIR), 100 NCL Innovation Park, Pune-411008, India. jayant.khandare@mippune.edu.in.
authors.forename: Shashwat S
authors.initials: SS
authors.lastname: Banerjee
authors.forename: Archana
authors.initials: A
authors.lastname: Jalota-Badhwar
authors.forename: Khushbu R
authors.initials: KR
authors.lastname: Zope
authors.forename: Kiran J
authors.initials: KJ
authors.lastname: Todkar
authors.forename: Russel R
authors.initials: RR
authors.lastname: Mascarenhas
authors.forename: Govind P
authors.initials: GP
authors.lastname: Chate
authors.forename: Ganesh V
authors.initials: GV
authors.lastname: Khutale
authors.forename: Atul
authors.initials: A
authors.lastname: Bharde
authors.forename: Marcelo
authors.initials: M
authors.lastname: Calderon
authors.forename: Jayant J
authors.initials: JJ
authors.lastname: Khandare
mesh_terms: D052203:Ferrosoferric Oxide / Q000737:chemistry; D045325:HCT116 Cells; D006801:Humans; D006861:Hydrogen Peroxide / Q000737:chemistry; D008024:Ligands; D058185:Magnetite Nanoparticles / Q000737:chemistry; D046529:Microscopy, Electron, Transmission; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009360:Neoplastic Cells, Circulating / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry; D013499:Surface Properties; D059008:Time-Lapse Imaging
chemical_list: D008024:Ligands; D058185:Magnetite Nanoparticles; D037742:Nanotubes, Carbon; D006861:Hydrogen Peroxide; D010100:Oxygen; D052203:Ferrosoferric Oxide