title: Organocatalyzed CO2 Trapping Using Alkynyl Indoles.
abstract: The first organocatalyzed trapping of CO2 through C-C and C-O bond formation is reported. Alkynyl indoles together with catalytic amounts of an organic base and five equivalents of CO2 resulted in the formation new heterocyclic structures. These tricyclic indole-containing products were successfully prepared under mild reaction conditions from aromatic, heteroaromatic, and aliphatic alkynyl indoles with complete regioselectivity. Further investigations suggest that C-C bond formation is the initial intermolecular step, followed by lactone-forming C-O bond formation.
authors.affiliation: Carbon Dioxide Activation Center (CADIAC), Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus (Denmark) http://www.skrydstrup-group.com.
authors.forename: Zhuo
authors.initials: Z
authors.lastname: Xin
authors.affiliation: Carbon Dioxide Activation Center (CADIAC), Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus (Denmark) http://www.skrydstrup-group.com.
authors.forename: Camille
authors.initials: C
authors.lastname: Lescot
authors.affiliation: Carbon Dioxide Activation Center (CADIAC), Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus (Denmark) http://www.skrydstrup-group.com.
authors.forename: Stig D
authors.initials: SD
authors.lastname: Friis
authors.affiliation: Carbon Dioxide Activation Center (CADIAC), Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus (Denmark) http://www.skrydstrup-group.com.
authors.forename: Kim
authors.initials: K
authors.lastname: Daasbjerg
authors.affiliation: Carbon Dioxide Activation Center (CADIAC), Interdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Gustav Wieds Vej 14, 8000 Aarhus (Denmark) http://www.skrydstrup-group.com. ts@chem.au.dk.
authors.forename: Troels
authors.initials: T
authors.lastname: Skrydstrup
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D053961:Azabicyclo Compounds / Q000737:chemistry*; D002245:Carbon Dioxide / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000480:Alkynes; D053961:Azabicyclo Compounds; D006571:Heterocyclic Compounds; D007211:Indoles; C526482:triazabicyclodecene; D002245:Carbon Dioxide
keywords: carbon dioxide; heterocycles; lactones; organocatalysis; synthetic methods