title: Incidence and phenotype at diagnosis of inflammatory bowel disease. Results in Spain of the EpiCom study.
abstract: BACKGROUND
  Incidence of inflammatory bowel disease (IBD) is increasing progressively. Few recent epidemiological prospective studies are available in Spain. The Epicom study, a population-based inception cohort of unselected IBD patients developed within the European Crohn's and Colitis Organization, was started in 2010. Vigo is the only Spanish area participating.
  
  
  OBJECTIVE
  To describe the incidence of IBD in the Vigo area and the phenotypical characteristics at diagnosis and to compare them with previous data available in Spain.
  
  
  METHODS
  Epidemiological, descriptive, prospective, and population-based study. All incident cases of IBD during 2010 and living in the Vigo area at diagnosis were included. The Copenhagen Diagnostic criteria were used to define cases. Background population at the start of the study was 579,632 inhabitants. Data were prospectively entered in the EpiCom database.
  
  
  RESULTS
  A total of 106 patients were included (57.5% men, median age 39.5 years). Of them 53 were diagnosed of as Crohn's disease (CD), 47 ulcerative colitis (UC) and six IBD unclassified (IBDU). The incidence rate per 100,000 per year for patients aged 15 years or older was 21.4 (10.8 for CD, 9.4 for UC, 1.2 IBDU). Including pediatric population incidence rates were 18.3 (10.3 CD, 8.7 UC, 1.2 IBDU). Median time since onset of symptoms until diagnosis was 2 months.
  
  
  CONCLUSIONS
  The incidence rate of IBD in Vigo is the highest compared to former Spanish cohorts, especially in CD patients. Median time since onset of symptoms until diagnosis is relatively short.
authors.affiliation: Servicio de Aparato Digestivo, Hospital POVISA, Vigo, Spain. Electronic address: afvillaverde@gmail.com.
authors.forename: Alberto
authors.initials: A
authors.lastname: Fernández
authors.affiliation: Servicio de Aparato Digestivo, Complexo Hospitalario Universitario de Vigo, Spain; 'IBIV' Institute of Biomedical Research of Vigo, Vigo, Spain.
authors.forename: Vicent
authors.initials: V
authors.lastname: Hernández
authors.affiliation: Servicio de Aparato Digestivo, Complexo Hospitalario Universitario de Vigo, Spain; 'IBIV' Institute of Biomedical Research of Vigo, Vigo, Spain; Hospital Perpetuo Socorro, Vigo, Spain.
authors.forename: David
authors.initials: D
authors.lastname: Martínez-Ares
authors.affiliation: Servicio de Aparato Digestivo, Complexo Hospitalario Universitario de Vigo, Spain; 'IBIV' Institute of Biomedical Research of Vigo, Vigo, Spain.
authors.forename: Luciano
authors.initials: L
authors.lastname: Sanromán
authors.affiliation: Servicio de Aparato Digestivo, Complexo Hospitalario Universitario de Vigo, Spain; 'IBIV' Institute of Biomedical Research of Vigo, Vigo, Spain.
authors.forename: María Luisa
authors.initials: ML
authors.lastname: de Castro
authors.affiliation: Servicio de Aparato Digestivo, Complexo Hospitalario Universitario de Vigo, Spain; 'IBIV' Institute of Biomedical Research of Vigo, Vigo, Spain; Hospital Fátima, Vigo, Spain.
authors.forename: Juan Ramón
authors.initials: JR
authors.lastname: Pineda
authors.affiliation: Servicio de Aparato Digestivo, Hospital POVISA, Vigo, Spain.
authors.forename: Amalia
authors.initials: A
authors.lastname: Carmona
authors.affiliation: Servicio de Aparato Digestivo, Hospital POVISA, Vigo, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: González-Portela
authors.affiliation: Servicio de Aparato Digestivo, Complexo Hospitalario Universitario de Vigo, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Salgado
authors.affiliation: Servicio de Aparato Digestivo, Complexo Hospitalario Universitario de Vigo, Spain; 'IBIV' Institute of Biomedical Research of Vigo, Vigo, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Martínez-Cadilla
authors.affiliation: Servicio de Aparato Digestivo, Complexo Hospitalario Universitario de Vigo, Spain; 'IBIV' Institute of Biomedical Research of Vigo, Vigo, Spain.
authors.forename: Santos
authors.initials: S
authors.lastname: Pereira
authors.affiliation: Servicio de Pediatria, Complexo Hospitalario Universitario de Vigo, Spain.
authors.forename: Jose Ignacio
authors.initials: JI
authors.lastname: García-Burriel
authors.affiliation: Servicio de Aparato Digestivo, Hospital POVISA, Vigo, Spain.
authors.forename: Santiago
authors.initials: S
authors.lastname: Vázquez
authors.affiliation: Servicio de Aparato Digestivo, Complexo Hospitalario Universitario de Vigo, Spain; 'IBIV' Institute of Biomedical Research of Vigo, Vigo, Spain.
authors.forename: Ignacio
authors.initials: I
authors.lastname: Rodríguez-Prada
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003093:Colitis, Ulcerative / Q000453:epidemiology; D003424:Crohn Disease / Q000453:epidemiology; D016208:Databases, Factual; D005260:Female; D006801:Humans; D015994:Incidence; D015212:Inflammatory Bowel Diseases / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009928:Organ Specificity; D010641:Phenotype; D011446:Prospective Studies; D013030:Spain / Q000453:epidemiology; D055815:Young Adult
keywords: Colitis ulcerosa; Crohn disease; Enfermedad de Crohn; Enfermedad inflamatoria intestinal; Epidemiology; Epidemiología; Incidence; Incidencia; Inflammatory bowel diseases; Ulcerative colitis