title: Polyethylenimine mediated silver nanoparticle-decorated magnetic graphene as a promising photothermal antibacterial agent.
abstract: A novel bactericidal material, Ag@rGO-Fe3O4-PEI composite is prepared by in situ growth of silver nanoparticles onto the polyethylenimine (PEI)-mediated magnetic reduced graphene oxide (GO). The antibacterial performances of the composite are investigated by using the gram-negative bacteria Escherichia coli O157:H7 (E. coli O157:H7) as a model. The results indicate that the Ag@rGO-Fe3O4-PEI composite exhibits excellent antibacterial performance against E. coli O157:H7, with an antibacterial performance superior to those for the ever-reported photothermal materials. The bactericidal capability or the inhibition capability for bacteria growth is found to depend on the dosage of the Ag@rGO-Fe3O4-PEI and Ag/rGO-Fe3O4-PEI mass ratio within a certain range. By using a dosage of 0.1 μg mL(-1), a killing rate of 99.9% is achieved for the E. coli O157:H7 (1 × 10(7) cfu mL(-1)) under a 0.5 min NIR laser irradiation (785 nm/50 mW cm(-2)). In addition, a minimum bactericidal concentration (MBC) of 0.100 μg mL(-1) is achieved under near infrared (NIR) laser irradiation for 10 min, for which case there is absolutely no colony of E. coli O157:H7 found in the broth agar plate.
authors.affiliation: Research Center for Analytical Sciences, College of Sciences, Northeastern University, Box 332, Shenyang 110819, People's Republic of China.
authors.forename: Ning
authors.initials: N
authors.lastname: Wang
authors.forename: Bo
authors.initials: B
authors.lastname: Hu
authors.forename: Ming-Li
authors.initials: ML
authors.lastname: Chen
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Wang
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D006108:Graphite / Q000737:chemistry*; D008027:Light; D060328:Magnetic Phenomena; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008826:Microbial Sensitivity Tests; D050296:Microbial Viability / Q000187:drug effects; D011094:Polyethyleneimine / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature
chemical_list: D000900:Anti-Bacterial Agents; D012834:Silver; D006108:Graphite; D011094:Polyethyleneimine