title: Clostridium perfringens infection after transarterial chemoembolization for large hepatocellular carcinoma.
abstract: We report an unusual case of Clostridium perfringens liver abscess formation after transcatheter arterial chemoembolization (TACE) for large hepatocellular carcinoma. Severe deterioration in liver and renal function accompanied with hemocytolysis was found on the 2(nd) day after TACE. Blood culture found Clostridium perfringens and abdominal computed tomography revealed a gas-containing abscess in the liver. Following antibiotics administration and support care, the infection was controlled and the liver and renal function turned normal. The 2(nd) TACE procedure was performed 1.5 mo later and no recurrent Clostridium perfringens infection was found.
authors.affiliation: Jing-Huan Li, Rong-Rong Yao, Hu-Jia Shen, Lan Zhang, Xiao-Ying Xie, Rong-Xin Chen, Yan-Hong Wang, Zheng-Gang Ren, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Jing-Huan
authors.initials: JH
authors.lastname: Li
authors.affiliation: Jing-Huan Li, Rong-Rong Yao, Hu-Jia Shen, Lan Zhang, Xiao-Ying Xie, Rong-Xin Chen, Yan-Hong Wang, Zheng-Gang Ren, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Rong-Rong
authors.initials: RR
authors.lastname: Yao
authors.affiliation: Jing-Huan Li, Rong-Rong Yao, Hu-Jia Shen, Lan Zhang, Xiao-Ying Xie, Rong-Xin Chen, Yan-Hong Wang, Zheng-Gang Ren, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Hu-Jia
authors.initials: HJ
authors.lastname: Shen
authors.affiliation: Jing-Huan Li, Rong-Rong Yao, Hu-Jia Shen, Lan Zhang, Xiao-Ying Xie, Rong-Xin Chen, Yan-Hong Wang, Zheng-Gang Ren, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Jing-Huan Li, Rong-Rong Yao, Hu-Jia Shen, Lan Zhang, Xiao-Ying Xie, Rong-Xin Chen, Yan-Hong Wang, Zheng-Gang Ren, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Xiao-Ying
authors.initials: XY
authors.lastname: Xie
authors.affiliation: Jing-Huan Li, Rong-Rong Yao, Hu-Jia Shen, Lan Zhang, Xiao-Ying Xie, Rong-Xin Chen, Yan-Hong Wang, Zheng-Gang Ren, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Rong-Xin
authors.initials: RX
authors.lastname: Chen
authors.affiliation: Jing-Huan Li, Rong-Rong Yao, Hu-Jia Shen, Lan Zhang, Xiao-Ying Xie, Rong-Xin Chen, Yan-Hong Wang, Zheng-Gang Ren, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Yan-Hong
authors.initials: YH
authors.lastname: Wang
authors.affiliation: Jing-Huan Li, Rong-Rong Yao, Hu-Jia Shen, Lan Zhang, Xiao-Ying Xie, Rong-Xin Chen, Yan-Hong Wang, Zheng-Gang Ren, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
authors.forename: Zheng-Gang
authors.initials: ZG
authors.lastname: Ren
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000628:therapy*; D016461:Chemoembolization, Therapeutic / Q000009:adverse effects*; D003015:Clostridium Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D003016:Clostridium perfringens / Q000302:isolation & purification*; D006801:Humans; D008100:Liver Abscess / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008113:Liver Neoplasms / Q000473:pathology / Q000628:therapy*; D008297:Male; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D047368:Tumor Burden
chemical_list: D000900:Anti-Bacterial Agents
keywords: Clostridium perfringens; Hepatocellular carcinoma; Liver abscess; Major complication; Transcatheter arterial chemoembolization