title: Acute respiratory distress syndrome in a child with severe epileptic disorder treated successfully by extracorporeal membrane oxygenation: a case report.
abstract: BACKGROUND
  Extracorporeal membrane oxygenation (ECMO) is now a candidate therapy for children with acute respiratory failure.
  
  
  METHODS
  We report our experience of using central ECMO therapy for acute respiratory distress syndrome followed by seizure in a 15-month-old girl with a severe epileptic disorder. Her respiratory distress was refractory to standard medical treatment and mechanical ventilatory support. Her condition was complicated by development of a pneumothorax. The patient was successfully weaned off ECMO and discharged without deterioration of her neurological status.
  
  
  CONCLUSIONS
  The successful outcome in this case resulted from the central ECMO, which enabled "lung rest" and adequate cerebral blood flow. In skilled ECMO facilities, early implementation of ECMO would give some advantages to patients such as the one presented here. Given the invasiveness and the ease of the procedure, introduction of dual-lumen catheters adequately sized for pediatric patients in Japan is required.
authors.affiliation: Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, Okayama, Japan. pv702xz5@s.okayama-u.ac.jp.|Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. pv702xz5@s.okayama-u.ac.jp.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Nosaka
authors.affiliation: Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, Okayama, Japan. ecmoshingo@gmail.com.|Department of Community and Emergency Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. ecmoshingo@gmail.com.
authors.forename: Shingo
authors.initials: S
authors.lastname: Ichiba
authors.affiliation: Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, Okayama, Japan. hei.trp@gmail.com.
authors.forename: Kohei
authors.initials: K
authors.lastname: Tsukahara
authors.affiliation: Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, Okayama, Japan. emily@rb4.so-net.ne.jp.
authors.forename: Emily
authors.initials: E
authors.lastname: Knaup
authors.affiliation: Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, Okayama, Japan. kumirin911@gmail.com.
authors.forename: Kumiko
authors.initials: K
authors.lastname: Hayashi
authors.affiliation: Department of Cardiovascular Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. shingok@md.okayama-u.ac.jp.
authors.forename: Shingo
authors.initials: S
authors.lastname: Kasahara
authors.affiliation: Department of Child Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. ykoba0628@gmail.com.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kobayashi
authors.affiliation: Department of Child Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. okamakio@cc.okayama-u.ac.jp.
authors.forename: Makio
authors.initials: M
authors.lastname: Oka
authors.affiliation: Department of Child Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. k_koba@md.okayama-u.ac.jp.
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Kobayashi
authors.affiliation: Department of Child Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. magenta@md.okayama-u.ac.jp.
authors.forename: Harumi
authors.initials: H
authors.lastname: Yoshinaga
authors.affiliation: Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, Okayama, Japan. ujike@cc.okayama-u.ac.jp.
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Ujike
mesh_terms: D004827:Epilepsy / Q000150:complications*; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006612:High-Frequency Ventilation / Q000009:adverse effects; D006801:Humans; D007223:Infant; D011030:Pneumothorax / Q000209:etiology; D012131:Respiratory Insufficiency / Q000150:complications* / Q000628:therapy*