title: Zero tolerance: amphipathic helices in endocytosis.
abstract: Endocytosis is the physical battle to form a new vesicle in the face of counteracting forces, such as membrane tension. Skruzny et al. (2015) and Miller et al. (2015) now shed light on endocytic proteins that bear a "Helix 0" and on the proteins' role in the struggle to make clathrin-coated vesicles.
authors.affiliation: Mechanochemical Cell Biology Building, Division of Biomedical Cell Biology, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK.
authors.forename: Laura A
authors.initials: LA
authors.lastname: Wood
authors.affiliation: Mechanochemical Cell Biology Building, Division of Biomedical Cell Biology, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK. Electronic address: s.j.royle@warwick.ac.uk.
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Royle
mesh_terms: D033942:Adaptor Proteins, Vesicular Transport / Q000378:metabolism*; D048430:Cell Shape / Q000235:genetics*; D022163:Clathrin-Coated Vesicles / Q000502:physiology*; D003034:Coated Pits, Cell-Membrane / Q000502:physiology*; D004023:Dictyostelium / Q000378:metabolism*; D004705:Endocytosis / Q000502:physiology*; D033721:Equilibrative Nucleoside Transporter 1 / Q000378:metabolism*; D050556:Fatty Acid-Binding Proteins / Q000235:genetics*; D006801:Humans; D034041:Monomeric Clathrin Assembly Proteins / Q000235:genetics* / Q000502:physiology*; D015003:Yeasts / Q000378:metabolism*
chemical_list: D033942:Adaptor Proteins, Vesicular Transport; D033721:Equilibrative Nucleoside Transporter 1; D050556:Fatty Acid-Binding Proteins; D034041:Monomeric Clathrin Assembly Proteins