title: Anesthetic management of a patient with Holt-Oram syndrome undergoing right radial head excision.
abstract: Holt-Oram syndrome also known as heart and hand syndrome, first reported in 1960. It is a rare, inherited, an autosomal dominant disorder with mutation in TBX5. As the name suggests, the feature involves skeletal abnormality mainly involving upper limb, that is, upper-extremity malformations involving radial, thenar, or carpal bones; congenital heart diseases like, atrial-septal defect and ventricular septal defect and conduction problems. This syndrome may also involve other part of skeletal structure. We hereby report a case of a patient who was suffering from this syndrome scheduled for right radial head excision.
authors.affiliation: Department of Anaesthesiology, Krishna Institute of Medical Sciences, Karad, Maharashtra, India.
authors.forename: Akshaya N
authors.initials: AN
authors.lastname: Shetti
authors.affiliation: Department of Anaesthesiology, Krishna Institute of Medical Sciences, Karad, Maharashtra, India.
authors.forename: Vithal K
authors.initials: VK
authors.lastname: Dhulkhed
authors.affiliation: Department of Anaesthesiology, Krishna Institute of Medical Sciences, Karad, Maharashtra, India.
authors.forename: Vinayak
authors.initials: V
authors.lastname: Panchgar
authors.affiliation: Department of Anaesthesiology, Krishna Institute of Medical Sciences, Karad, Maharashtra, India.
authors.forename: Lokesh
authors.initials: L
authors.lastname: Prakash
keywords: Anesthesia; Holt-Oram syndrome; atrial-septal defect; heart and hand syndrome; polydactyly