title: Osteoblast ablation burns out functional stem cells.
abstract: In this issue of Blood, Bowers et al report that osteoblasts maintain a subset of quiescent stem cells and that osteoblast ablation converts bone marrow into a proliferation-promoting environment for both normal and malignant stem cells.
authors.affiliation: STOWERS INSTITUTE FOR MEDICAL RESEARCH;
authors.forename: Meng
authors.initials: M
authors.lastname: Zhao
authors.affiliation: STOWERS INSTITUTE FOR MEDICAL RESEARCH; UNIVERSITY OF KANSAS MEDICAL CENTER.
authors.forename: Linheng
authors.initials: L
authors.lastname: Li
mesh_terms: D000818:Animals; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000473:pathology*; D014411:Neoplastic Stem Cells / Q000473:pathology*; D010006:Osteoblasts / Q000166:cytology*