title: Laryngeal tuberculosis diagnosed by stool sample cultures: a case report.
abstract: BACKGROUND
  Laryngeal tuberculosis is a rare and often misdiagnosed disease. Its diagnosis is based on the association of a laryngeal lesion and the microbiological detection of Mycobacterium tuberculosis. Stool cultures have recently been described as a useful tool in the diagnosis of atypical forms of tuberculosis. In this report, we describe the first case in the literature of laryngeal tuberculosis diagnosed by culture of stool samples.
  
  
  METHODS
  A 41-year-old French Caucasian man was admitted to our hospital for dysphonia of 3 months' evolution. A laryngeal biopsy was performed because of suspicion of carcinoma. He had no clinical signs of tuberculosis. The biopsy showed a caseating granuloma suggestive of laryngeal tuberculosis. The diagnosis was finally confirmed by stool cultures, whereas sputum cultures remained sterile for M. tuberculosis.
  
  
  CONCLUSIONS
  This case confirms the importance of stool cultures in the diagnosis of tuberculosis, especially for patients with uncommon presentations.
authors.affiliation: Assistance Publique-Hôpitaux de Marseille, CHU Nord, Pôle Infectieux, Institut Hospitalo-Universitaire Méditerranée Infection, 13015, Marseille, France. nicolas.yin@yahoo.fr.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Yin
authors.affiliation: Assistance Publique-Hôpitaux de Marseille, CHU Nord, Pôle Infectieux, Institut Hospitalo-Universitaire Méditerranée Infection, 13015, Marseille, France. marion.delord@ap-hm.fr.
authors.forename: Marion
authors.initials: M
authors.lastname: Delord
authors.affiliation: Service d'ORL et de chirurgie cervico-faciale, CHRU La Timone, 264, rue Saint-Pierre, 13385, Marseille, cedex 05, France. antoine.giovanni@ap-hm.fr.
authors.forename: Antoine
authors.initials: A
authors.lastname: Giovanni
authors.affiliation: Service d'Anatomo-pathologie, Assistance Publique-Hôpitaux de Marseille, Hôpital de la Timone, Marseille, France. jean.del-grande@ap-hm.fr.
authors.forename: Jean
authors.initials: J
authors.lastname: del Grande
authors.affiliation: Aix Marseille Université, URMITE, UMR63, CNRS 7278, IRD 198, Inserm 1095, Marseille, France. michel.drancourt@ap-hm.fr.
authors.forename: Michel
authors.initials: M
authors.lastname: Drancourt
authors.affiliation: Assistance Publique-Hôpitaux de Marseille, CHU Nord, Pôle Infectieux, Institut Hospitalo-Universitaire Méditerranée Infection, 13015, Marseille, France. philippe.brouqui@ap-hm.fr.|Aix Marseille Université, URMITE, UMR63, CNRS 7278, IRD 198, Inserm 1095, Marseille, France. philippe.brouqui@ap-hm.fr.
authors.forename: Philippe
authors.initials: P
authors.lastname: Brouqui
authors.affiliation: Assistance Publique-Hôpitaux de Marseille, CHU Nord, Pôle Infectieux, Institut Hospitalo-Universitaire Méditerranée Infection, 13015, Marseille, France. jean-christophe.lagier@ap-hm.fr.|Aix Marseille Université, URMITE, UMR63, CNRS 7278, IRD 198, Inserm 1095, Marseille, France. jean-christophe.lagier@ap-hm.fr.
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Lagier
mesh_terms: D000328:Adult; D001706:Biopsy / Q000379:methods; D003937:Diagnosis, Differential; D055154:Dysphonia / Q000209:etiology*; D005243:Feces / Q000382:microbiology*; D006099:Granuloma / Q000150:complications / Q000473:pathology; D006801:Humans; D007830:Larynx / Q000473:pathology; D008297:Male; D014387:Tuberculosis, Laryngeal / Q000150:complications / Q000175:diagnosis*