title: Gallium(III)-Promoted Halocyclizations of 1,6-Diynes.
abstract: Cyclization of 1,6-diynes promoted by stoichiometric Ga(III) halides produces vinyl halides in good to excellent yields. Under acidic conditions, initially formed iodocyclization products undergo in situ Friedel-Crafts cyclizations, giving access to iodoindenopyridines. Application of the vinyl halides in cross-coupling reactions has been explored, and mechanistic aspects of the cyclization are discussed.
authors.affiliation: Department of Chemistry Boston University, Boston, Massachusetts 02215, United States.
authors.forename: Kyle R
authors.initials: KR
authors.lastname: Strom
authors.affiliation: Department of Chemistry Boston University, Boston, Massachusetts 02215, United States.
authors.forename: Anna C
authors.initials: AC
authors.lastname: Impastato
authors.affiliation: Department of Chemistry Boston University, Boston, Massachusetts 02215, United States.
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Moy
authors.affiliation: Department of Chemistry Boston University, Boston, Massachusetts 02215, United States.
authors.forename: Adrian J
authors.initials: AJ
authors.lastname: Landreth
authors.affiliation: Department of Chemistry Boston University, Boston, Massachusetts 02215, United States.
authors.forename: John K
authors.initials: JK
authors.lastname: Snyder