title: Atypical postcesarean epithelioid trophoblastic lesion with cyst formation: a case report and literature review.
abstract: We report an extremely rare case of atypical postcesarean epithelioid trophoblastic lesion with cyst formation. A 41-year-old Chinese woman presented with lower abdominal pain and menstrual disorder. Her serum human chorionic gonadotropin (hCG) was low (0.373 IU/L), and her urine hCG was negative. Ultrasound images showed a 3.7×2.8×2.5 cm(3) mass on the surface of the lower uterine segment, and a laparoscopy indicated a cystic mass in the serosal surface of the lower uterine segment. Histology indicated a cystic lesion consisting of epithelioid trophoblastic cells with an intermediate pattern between a classical placental site nodule and an epithelioid trophoblastic tumor; thus, the term atypical postcesarean epithelioid trophoblastic lesion with cyst formation was appropriate. As in atypical placental site nodule, serum hCG monitoring after treatment is necessary.
authors.affiliation: Department of Pathology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310006, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Zhou
authors.affiliation: Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310006, China.
authors.forename: Kaiqing
authors.initials: K
authors.lastname: Lin
authors.affiliation: Department of Pathology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310006, China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Shi
authors.affiliation: Department of Ultrasound, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310006, China.
authors.forename: Jiale
authors.initials: J
authors.lastname: Qin
authors.affiliation: Department of Pathology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310006, China.
authors.forename: Bingjian
authors.initials: B
authors.lastname: Lu
authors.affiliation: Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310006, China. Electronic address: 29402335@qq.com.
authors.forename: Lili
authors.initials: L
authors.lastname: Huang
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D002585:Cesarean Section / Q000009:adverse effects*; D006063:Chorionic Gonadotropin / Q000097:blood / Q000652:urine; D015622:Epithelioid Cells / Q000737:chemistry / Q000473:pathology*; D005260:Female; D031901:Gestational Trophoblastic Disease / Q000737:chemistry / Q000145:classification / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D018297:Neoplasms, Cystic, Mucinous, and Serous / Q000737:chemistry / Q000145:classification / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D011237:Predictive Value of Tests; D011247:Pregnancy; D009626:Terminology as Topic; D014594:Uterine Neoplasms / Q000737:chemistry / Q000145:classification / Q000209:etiology* / Q000473:pathology / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin
keywords: Cyst formation; Epithelioid; Intermediate trophoblastic cells; Postcesarean delivery; Uterus