title: [Predictive value of serum iron level for in-hospital acute heart failure after acute ST-elevated myocardial infarction].
abstract: OBJECTIVE
  To evaluate the predictive value of serum iron level for in-hospital acute heart failure (AHF) after acute ST-elevated myocardial infarction (STEMI).
  
  
  METHODS
  This retrospective study involved 287 patients with STEMI stratified by quartiles of admission serum iron concentration. The incidence of AHF was assessed by serum iron quartiles. We evaluated the association of serum iron levels with B-type natriuretic peptide (BNP), cardiac troponin I (cTnI), and high-sensitivity C-reactive protein (hs-CRP) levels on admission, and analyzed the correlation of serum iron levels with in-hospital AHF, death, and duration of hospital stay.
  
  
  RESULTS
  The average serum iron level on admission of the 287 STEMI patients was 10.20 µmol/L (6.90-14.40 µmol/L), and the quartiles (Q) of serum iron levels were ≤6.90 µmol/L (Q(1)), 6.91-10.19 µmol/L (Q(2)), 10.20-14.39 µmol/L (Q(3)), and ≥14.40 µmol/L (Q(4)). The incidences of in-hospital AHF from Q(1) to Q(4) were 79.5%, 64.3%, 50.0% and 45.9%, respectively (P<0.001). Univariate logistic regression analysis showed that low admission serum iron level (Q(1)) was an independent predictor for in-hospital AHF (OR=3.358, 95%CI 1.791- 6.294, P<0.001), and multivariate logistic regression analysis showed a similar result (OR=2.316, 95%CI 1.205-4.453, P=0.012).
  
  
  CONCLUSIONS
  A lower admission serum iron level is an independent predictor of AHF in STEMI patients during hospitalization.
authors.affiliation: Department of Internal Medicine, Guangzhou 510632, China;. E-mail: dr.yegang@qq.com.
authors.forename: Gang
authors.initials: G
authors.lastname: Ye
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.forename: Jian
authors.initials: J
authors.lastname: Yu
authors.forename: Feng
authors.initials: F
authors.lastname: Gan
authors.forename: Hong-Cheng
authors.initials: HC
authors.lastname: Wei
mesh_terms: D000208:Acute Disease; D002097:C-Reactive Protein / Q000032:analysis; D006333:Heart Failure / Q000097:blood* / Q000175:diagnosis; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007501:Iron / Q000097:blood*; D009203:Myocardial Infarction / Q000097:blood*; D020097:Natriuretic Peptide, Brain / Q000032:analysis; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D019210:Troponin I / Q000032:analysis
chemical_list: D019210:Troponin I; D020097:Natriuretic Peptide, Brain; D002097:C-Reactive Protein; D007501:Iron