title: Dummy molecularly imprinted mesoporous silica prepared by hybrid imprinting method for solid-phase extraction of bisphenol A.
abstract: A novel hybrid dummy imprinting strategy was developed to prepare a mesoporous silica for the solid-phase extraction (SPE) of bisphenol A (BPA). A new covalent template-monomer complex (BPAF-Si) was first synthesized with 2,2-bis(4-hydroxyphenyl)hexafluoropropane (BPAF) as the template. The imprinted silica was obtained through the gelation of BPAF-Si with tetraethoxysilane and the subsequent removal of template by thermal cleavage, and then it was characterized by FT-IR spectroscopy, scanning electron microscopy, transmission electron microscopy, and nitrogen adsorption-desorption isotherms. Results showed that the new silica had micron-level particle size and ordered mesoporous structure. The static binding test verified that the imprinted silica had much higher recognition ability for BPA than the non-imprinted silica. The imprinted silica also showed high extraction efficiencies and high enrichment factor for SPE of BPA. Using the imprinted silica, a SPE-HPLC-UV method was developed and successfully applied for detecting BPA in BPA-spiked tap water and lake water samples with a recovery of 99-105%, a RSD of 2.7-5.0% and a limit of detection (S/N=3) of 0.3ng/mL. The new imprinted silica avoided the interference of the residual template molecules and reduced the non-specific binding sites, and therefore it can be utilized as a good sorbent for SPE of BPA in environmental water samples.
authors.affiliation: School of Chemistry and Chemical Engineering, Wuhan Textile University, 1 Textile Road, Wuhan 430073, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Yu
authors.affiliation: School of Chemistry and Chemical Engineering, Wuhan Textile University, 1 Textile Road, Wuhan 430073, China.
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Hu
authors.affiliation: School of Chemistry and Chemical Engineering, Wuhan Textile University, 1 Textile Road, Wuhan 430073, China.
authors.forename: Shoutai
authors.initials: S
authors.lastname: Wei
authors.affiliation: School of Chemistry and Chemical Engineering, Wuhan Textile University, 1 Textile Road, Wuhan 430073, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
authors.affiliation: School of Chemistry and Chemical Engineering, Wuhan Textile University, 1 Textile Road, Wuhan 430073, China. Electronic address: chiyanghe@hotmail.com.
authors.forename: Chiyang
authors.initials: C
authors.lastname: He
authors.affiliation: Department of Chemistry and Biochemistry, University of Oklahoma, 101 Stephenson Parkway, Norman, OK 73019, USA.
authors.forename: Shaorong
authors.initials: S
authors.lastname: Liu
mesh_terms: D000327:Adsorption; D001559:Benzhydryl Compounds / Q000737:chemistry / Q000302:isolation & purification*; D002851:Chromatography, High Pressure Liquid; D005618:Fresh Water / Q000737:chemistry; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D054802:Molecular Imprinting; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation* / Q000379:methods; D017550:Spectroscopy, Fourier Transform Infrared; D014874:Water Pollutants, Chemical / Q000032:analysis*; D000098826:Bisphenol A Compounds; D005466:Fluorocarbons
chemical_list: D001559:Benzhydryl Compounds; D006845:Hydrocarbons, Fluorinated; D010636:Phenols; D012822:Silicon Dioxide; D014874:Water Pollutants, Chemical; C006780:bisphenol A; D000098826:Bisphenol A Compounds; C583074:bisphenol AF; D005466:Fluorocarbons
keywords: Bisphenol A; Dummy molecular imprinting; HPLC-UV; Hybrid imprinting; Ordered mesoporous silica; Solid-phase extraction