title: Integrating host gene expression and the microbiome to explore disease pathogenesis.
abstract: In a recent study, rich clinical assessment and longitudinal study design are combined with host gene expression and microbial sequencing analyses to develop a framework for exploring disease etiology and outcomes in the context of human inflammatory disease.See related article: http://dx.doi.org/10.1186/s13059-015-0637-x.
authors.affiliation: Microbial Genomics Section, Translational and Functional Genomics Branch, National Human Genome Research Institute, Bethesda, MD, 20892, USA. allyson.byrd@nih.gov.
authors.forename: Allyson L
authors.initials: AL
authors.lastname: Byrd
authors.affiliation: Microbial Genomics Section, Translational and Functional Genomics Branch, National Human Genome Research Institute, Bethesda, MD, 20892, USA. jsegre@nhgri.nih.gov.
authors.forename: Julia A
authors.initials: JA
authors.lastname: Segre
mesh_terms: D015964:Gene Expression Regulation, Bacterial; D006790:Host-Parasite Interactions / Q000235:genetics*; D006801:Humans; D007249:Inflammation / Q000235:genetics* / Q000382:microbiology / Q000473:pathology; D064307:Microbiota / Q000235:genetics*