title: Gradients are shaping up.
abstract: In animal embryos, morphogen gradients determine tissue patterning and morphogenesis. Shyer et al. provide evidence that, during vertebrate gut formation, tissue folding generates graded activity of signals required for subsequent steps of gut growth and differentiation, thereby revealing an intriguing link between tissue morphogenesis and morphogen gradient formation.
authors.affiliation: Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
authors.forename: Tobias
authors.initials: T
authors.lastname: Bollenbach
authors.affiliation: Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria. Electronic address: heisenberg@ist.ac.at.
authors.forename: Carl-Philipp
authors.initials: CP
authors.lastname: Heisenberg
mesh_terms: D053687:Adult Stem Cells / Q000166:cytology*; D000818:Animals; D007421:Intestine, Small / Q000166:cytology*; D040542:Mechanotransduction, Cellular