title: Emergence of azole-resistant Candida albicans in small ruminants.
abstract: Small ruminant production is a common agricultural activity worldwide. However, studies on the fungal microbiota of these animals are scarce. Therefore, this study aimed at isolating yeasts from goats and sheep and evaluating the antifungal susceptibility of the recovered Candida albicans. A total of 120 animals from farms in Ceará State, Brazil, were assessed in this study. The samples were collected from nasal, oral and rectal cavities with sterile swabs. Candida spp., Trichosporon spp. and Rhodotorula spp. were isolated from small ruminants. Resistance to three azole drugs was observed in C. albicans. In summary, Candida spp. were predominantly observed as part of the microbiota of the nasal, oral and rectal cavities of small ruminants, including azole-resistant strains of C. albicans.
authors.affiliation: Postgraduate Program in Medical Microbiology, Department of Pathology and Legal Medicine, Specialized Medical Mycology Center, School of Medicine, Federal University of Ceará, Rua Coronel Nunes de Melo, Fortaleza, CE, 1315, Brazil, brilhante@ufc.br.
authors.forename: R S N
authors.initials: RS
authors.lastname: Brilhante
authors.forename: S T C
authors.initials: ST
authors.lastname: Silva
authors.forename: D S C M
authors.initials: DS
authors.lastname: Castelo-Branco
authors.forename: C E C
authors.initials: CE
authors.lastname: Teixeira
authors.forename: L C
authors.initials: LC
authors.lastname: Borges
authors.forename: P V
authors.initials: PV
authors.lastname: Bittencourt
authors.forename: J S
authors.initials: JS
authors.lastname: de Oliveira
authors.forename: A J
authors.initials: AJ
authors.lastname: Monteiro
authors.forename: T J P G
authors.initials: TJ
authors.lastname: Bandeira
authors.forename: R A
authors.initials: RA
authors.lastname: Cordeiro
authors.forename: J L B
authors.initials: JL
authors.lastname: Moreira
authors.forename: J J C
authors.initials: JJ
authors.lastname: Sidrim
authors.forename: M F G
authors.initials: MF
authors.lastname: Rocha
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D001393:Azoles / Q000494:pharmacology*; D001938:Brazil; D002176:Candida albicans / Q000302:isolation & purification*; D025141:Drug Resistance, Fungal; D006041:Goats / Q000382:microbiology*; D009055:Mouth / Q000382:microbiology; D009296:Nasal Cavity / Q000382:microbiology; D012007:Rectum / Q000382:microbiology; D012248:Rhodotorula / Q000302:isolation & purification; D012756:Sheep / Q000382:microbiology*; D014250:Trichosporon / Q000302:isolation & purification
chemical_list: D000935:Antifungal Agents; D001393:Azoles