title: Evaluation of bone formation after sagittal split ramus osteotomy using different fixation materials.
abstract: OBJECTIVE
  The purpose of this study was to evaluate bony change between the proximal and distal segments after sagittal split ramus osteotomy (SSRO) using different fixation materials.
  
  
  METHODS
  The subjects consisted of 74 patients (21 male and 53 female; 148 sides) who underwent SSRO with and without Le Fort I osteotomy. They were divided into five groups: (1) an MT group, mono-cortical titanium plate fixation (26 sides); (2) an MA group, mono-cortical absorbable plate fixation (48 sides); (3) a BA group, bi-cortical absorbable plate fixation (22 sides); (4) an MAα group, mono-cortical plate absorbable fixation with α-tricalcium phosphate (36 sides); and (5) a BAα group, bi-cortical plate absorbable fixation with α-tricalcium phosphate (16 sides). Ramus square (RmS), ramus width (RmM-RmL) and ramus length (RmA-RmP) at the horizontal plane under the mandibular foramen were assessed pre-operatively, immediately after surgery, and at 1 year after surgery by computed tomography (CT).
  
  
  RESULTS
  There were significant differences among the groups regarding change over time in RmS (p = 0.0126) and RmM-RmL (p = 0.0001). However, there was no significant difference among the groups regarding change over time in RmA-RmP.
  
  
  CONCLUSIONS
  These results suggest that the use of different fixation materials leads to significant differences in the bone healing process after SSRO.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, 1110, Shimokato, Chuoshi 409-3821, Japan. Electronic address: kueki@yamanashi.ac.jp.
authors.forename: Koichiro
authors.initials: K
authors.lastname: Ueki
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, 1110, Shimokato, Chuoshi 409-3821, Japan.
authors.forename: Yuri
authors.initials: Y
authors.lastname: Ishihara
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, 1110, Shimokato, Chuoshi 409-3821, Japan.
authors.forename: Kunio
authors.initials: K
authors.lastname: Yoshizawa
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, 1110, Shimokato, Chuoshi 409-3821, Japan.
authors.forename: Akinori
authors.initials: A
authors.lastname: Moroi
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, 1110, Shimokato, Chuoshi 409-3821, Japan.
authors.forename: Hiroumi
authors.initials: H
authors.lastname: Ikawa
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, 1110, Shimokato, Chuoshi 409-3821, Japan.
authors.forename: Ran
authors.initials: R
authors.lastname: Iguchi
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, 1110, Shimokato, Chuoshi 409-3821, Japan.
authors.forename: Akihiko
authors.initials: A
authors.lastname: Kosaka
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, 1110, Shimokato, Chuoshi 409-3821, Japan.
authors.forename: Asami
authors.initials: A
authors.lastname: Hotta
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, 1110, Shimokato, Chuoshi 409-3821, Japan.
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Tsutsui
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Clinical Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, 1110, Shimokato, Chuoshi 409-3821, Japan.
authors.forename: Yuriko
authors.initials: Y
authors.lastname: Saida
mesh_terms: D020341:Absorbable Implants; D000293:Adolescent; D000328:Adult; D001672:Biocompatible Materials / Q000737:chemistry; D001860:Bone Plates; D002130:Calcium Phosphates / Q000737:chemistry; D002508:Cephalometry / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000502:physiology* / Q000601:surgery; D008875:Middle Aged; D010012:Osteogenesis / Q000502:physiology*; D019340:Osteotomy, Le Fort / Q000379:methods; D059229:Osteotomy, Sagittal Split Ramus / Q000295:instrumentation*; D011378:Prognathism / Q000601:surgery; D012189:Retrospective Studies; D014025:Titanium / Q000737:chemistry; D014057:Tomography, X-Ray Computed / Q000379:methods; D055815:Young Adult
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; D014025:Titanium
keywords: Bone formation; Computed tomography; Fixation material; Sagittal split ramus osteotomy