title: Comparison of vital capacity induction with sevoflurane to intravenous induction with propofol in adult patients.
abstract: BACKGROUND
  Various techniques exist for gaseous induction in adults. Vital capacity induction (VCI) is a special technique for gaseous induction of anesthesia.
  
  
  OBJECTIVE
  We compared the two methods for time of induction, vital parameters at induction, and suitability for laryngeal mask insertion and its effects, if any on the emergence and postoperative cognitive function tests.
  
  
  METHODS
  A total of 60 adult American Society of Anesthesiologists grades I and II gynecological patients were randomly allocated into two groups of 30 each.
  
  
  METHODS
  Group "S" received VCI with 8% sevoflurane in 8 l/min oxygen and group "P" received intravenous induction with propofol after premedication. Laryngeal mask airway (LMA) was inserted and anesthesia maintained with oxygen, nitrous oxide, and sevoflurane in both groups. Induction time, corresponding entropy, vital parameters, and emergence time were noted. Postoperative cognitive and psychomotor functions were noted with P-deletion test, digit symbol substitution test, and finger nose test.
  
  
  METHODS
  Unpaired t-test and Fisher exact test.
  
  
  RESULTS
  Time for induction was 61 ± 32 s and 31 ± 10.8 s for VCI (group S) and propofol (group P), respectively. The difference was statistically significant (P = 0.001). About 70% patients in VCI had excellent conditions for LMA insertion when compared with 76% in propofol group (P = 0.3855). The incidence of airway complications, emergence times, and recovery of postoperative cognitive functions was not significantly different in both groups.
  
  
  CONCLUSIONS
  VCI provides an induction and recovery comparable to propofol induction.
authors.affiliation: Department of Anesthesia, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India.
authors.forename: Dhanashree H
authors.initials: DH
authors.lastname: Dongare
authors.affiliation: Department of Anesthesia, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India.
authors.forename: Jyothi V
authors.initials: JV
authors.lastname: Kale
authors.affiliation: Department of Anesthesia, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India.
authors.forename: Ramesh W
authors.initials: RW
authors.lastname: Naphade
keywords: Propofol; sevoflurane; vital capacity induction