title: Estimation of minimally important differences in the EQ-5D and SF-6D indices and their utility in stroke.
abstract: BACKGROUND
  The aim of the present study was to estimate minimally important differences (MIDs) in EQ-5D and SF-6D indices and to explore the responsiveness of EQ-5D and SF-6D indices in stroke.
  
  
  METHODS
  We used observational longitudinal survey data of EQ-5D and SF-36 that were administered to stroke patients at baseline and at 10 months. A range of MIDs for both indexes was estimated using anchor-based approaches. The modified Rankin scale and the Barthel index were used as an anchor.
  
  
  RESULTS
  The MID estimates for EQ-5D ranged from 0.08 to 0.12 and those for SF-6D ranged from 0.04 to 0.14 in stroke patients. The MID values for these two utility measures differed in absolute magnitude, as the SF-6D index has wider range that that of the EQ-5D index.
  
  
  CONCLUSIONS
  The MID values for these two utility measures differed in absolute magnitude, as the SF-6D index has wider range that that of the EQ-5D index. These MID estimates may assist the interpretation of health related quality of life assessments related to health care intervention in stroke patients.
authors.affiliation: Department of Preventive Medicine, Dongguk University College of Medicine, 123, Dongdae-ro, Gyeongju-si, Gyeongbuk, South Korea. dunggly@dongguk.ac.kr.
authors.forename: Sang-Kyu
authors.initials: SK
authors.lastname: Kim
authors.affiliation: Department of Nursing, Dankook University, 119 Dandae-ro, Dongnam-gu, Cheonan-si, Chungnam, South Korea. kshgive@gmail.com.
authors.forename: Seon-Ha
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Preventive Medicine, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, South Korea. mdjominwoo@gmail.com.
authors.forename: Min-Woo
authors.initials: MW
authors.lastname: Jo
authors.affiliation: Department of Preventive Medicine, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, South Korea. sleemd@amc.seoul.kr.
authors.forename: Sang-il
authors.initials: SI
authors.lastname: Lee
mesh_terms: D000368:Aged; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011594:Psychometrics; D011788:Quality of Life / Q000523:psychology*; D057566:Self Report; D020521:Stroke / Q000523:psychology*; D000071939:Stroke Rehabilitation; D011795:Surveys and Questionnaires