title: Design, materials, and mechanobiology of biodegradable scaffolds for bone tissue engineering.
abstract: A review about design, manufacture, and mechanobiology of biodegradable scaffolds for bone tissue engineering is given. First, fundamental aspects about bone tissue engineering and considerations related to scaffold design are established. Second, issues related to scaffold biomaterials and manufacturing processes are discussed. Finally, mechanobiology of bone tissue and computational models developed for simulating how bone healing occurs inside a scaffold are described.
authors.affiliation: Studies and Applications in Mechanical Engineering Research Group (GEAMEC), Universidad Santo Tomás, Bogotá, Colombia.
authors.forename: Marco A
authors.initials: MA
authors.lastname: Velasco
authors.affiliation: Studies and Applications in Mechanical Engineering Research Group (GEAMEC), Universidad Santo Tomás, Bogotá, Colombia ; Biomimetics Laboratory and Numerical Methods and Modeling Research Group (GNUM), Instituto de Biotecnología (IBUN), Universidad Nacional de Colombia, Bogotá, Colombia.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Narváez-Tovar
authors.affiliation: Biomimetics Laboratory and Numerical Methods and Modeling Research Group (GNUM), Instituto de Biotecnología (IBUN), Universidad Nacional de Colombia, Bogotá, Colombia.
authors.forename: Diego A
authors.initials: DA
authors.lastname: Garzón-Alvarado
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D018786:Bone Substitutes; D006801:Humans; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds
chemical_list: D018786:Bone Substitutes