title: Antimicrobial Drug Resistance of Vibrio cholerae, Democratic Republic of the Congo.
abstract: We analyzed 1,093 Vibrio cholerae isolates from the Democratic Republic of the Congo during 1997-2012 and found increasing antimicrobial drug resistance over time. Our study also demonstrated that the 2011-2012 epidemic was caused by an El Tor variant clonal complex with a single antimicrobial drug susceptibility profile.
authors.forename: Berthe
authors.initials: B
authors.lastname: Miwanda
authors.forename: Sandra
authors.initials: S
authors.lastname: Moore
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Muyembe
authors.forename: Georges
authors.initials: G
authors.lastname: Nguefack-Tsague
authors.forename: Ickel Kakongo
authors.initials: IK
authors.lastname: Kabangwa
authors.forename: Daniel Yassa
authors.initials: DY
authors.lastname: Ndjakani
authors.forename: Ankur
authors.initials: A
authors.lastname: Mutreja
authors.forename: Nicholas
authors.initials: N
authors.lastname: Thomson
authors.forename: Helene
authors.initials: H
authors.lastname: Thefenne
authors.forename: Eric
authors.initials: E
authors.lastname: Garnotel
authors.forename: Gaston
authors.initials: G
authors.lastname: Tshapenda
authors.forename: Denis Kandolo
authors.initials: DK
authors.lastname: Kakongo
authors.forename: Guy
authors.initials: G
authors.lastname: Kalambayi
authors.forename: Renaud
authors.initials: R
authors.lastname: Piarroux
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002771:Cholera / Q000188:drug therapy / Q000453:epidemiology* / Q000266:history / Q000382:microbiology*; D015023:Democratic Republic of the Congo / Q000453:epidemiology; D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial; D005843:Geography; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008826:Microbial Sensitivity Tests; D058885:Multilocus Sequence Typing; D010802:Phylogeny; D014734:Vibrio cholerae / Q000145:classification / Q000187:drug effects* / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents
keywords: Democratic Republic of the Congo; El Tor variant; MLVA; Vibrio cholerae O1; antimicrobial resistance; bacteria; cholera; clone; whole-genome sequencing