title: Hypertensive urgency after administration of a single low dose of mirtazapine-a case report.
abstract: Mirtazapine is a new antidepressant that can increase noradrenergic and serotonergic neurotransmission. It is also a postsynaptic antagonist of 5-HT2 and 5-HT3. In addition, it has only a weak affinity for 5-HT1 receptors and has very weak muscarinic anticholinergic and histamine (H1) antagonist properties. We report a case of hypertensive urgency that ensued after a patient took a single low dose of mirtazapine.
authors.affiliation: Dept. of Pharmacy, Tongde Hospital of Zhejiang Province, Hangzhou, China ; Dept. of Pharmacology, Toxicology and Biochemical Pharmaceutics, Zhejiang University, Hangzhou, China.
authors.forename: Jiana
authors.initials: J
authors.lastname: Shi
authors.affiliation: Dept. of Pharmacy, Tongde Hospital of Zhejiang Province, Hangzhou, China.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Wang
authors.affiliation: Dept. of Pharmacy, Tongde Hospital of Zhejiang Province, Hangzhou, China.
authors.forename: Yin
authors.initials: Y
authors.lastname: Ying
authors.affiliation: Dept. of Cardiovascular Medicine, Tongde Hospital of Zhejiang Province, Hangzhou, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Xu
authors.affiliation: Dept. of Pharmacology, Toxicology and Biochemical Pharmaceutics, Zhejiang University, Hangzhou, China.
authors.forename: Danyan
authors.initials: D
authors.lastname: Zhu
keywords: Antidepressant; Hypertensive urgency; Mirtazapine