title: Ultrastructural Analysis of the Prostate Gland under the Effect of Factors of Chemical Industry.
abstract: We analyzed ultrastruciture of the cell populations in the prostate gland in chronic nonbacterial prostatitis in a chemical industry worker. It was shown that ultrastructural reorganization of the epithelium consisted in reduction of the secretory compartment of the cytoplasm and dystrophic-degenerative changes in cell organelles. Endothelial cells of the capillaries showed signs of significant degeneration and low intensity of micropinocytosis. Most of the smooth muscle cells underwent dystrophic-degenerative modifications of ultrastructural elements. The dominance of degenerative cell changes in the epithelial and stromal cell populations along with intensification of collagen formation in the absence of inflammatory elements allows us to interpret this pathological condition of the prostate gland as prostate pathology of occupational or mixed genesis.
authors.affiliation: Siberian Division of the Russian Academy of Medical Sciences, Institute of Regional Pathology and Pathomorphology, Novosibirsk, Russia, pathol@inbox.ru.
authors.forename: L M
authors.initials: LM
authors.lastname: Nepomnyashchikh
authors.forename: G A
authors.initials: GA
authors.lastname: Lapiy
authors.forename: D B
authors.initials: DB
authors.lastname: Nikityuk
authors.forename: A I
authors.initials: AI
authors.lastname: Neimark
authors.forename: A V
authors.initials: AV
authors.lastname: Kiptilov
authors.forename: O P
authors.initials: OP
authors.lastname: Molodykh
mesh_terms: D000328:Adult; D002617:Chemical Industry / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000187:drug effects / Q000648:ultrastructure*; D011472:Prostatitis / Q000139:chemically induced / Q000473:pathology; D013464:Sulfuric Acids / Q000633:toxicity
chemical_list: D013464:Sulfuric Acids; C033158:sulfuric acid