title: Synthesis, insecticidal, and fungicidal screening of some new synthetic quinoline derivatives.
abstract: This paper describes the synthesis of a series of quinolines graphted with hydrazones, pyrazoles, pyridazine, phthalazine, triazepinone, semicarbazide, and thiomorpholide moieties and four metal complexes. These derivatives were screened against Fusarium oxysporum and the red palm weevil (RPW) Rhynchophorus ferrugineus Oliver (coleopteran: Curculionidae) as palm pathogens. Only chlorinated quinolines were active against these organisms with hydrazones being good fungicides, while those modified with pyrazoles and pyrazines showed moderate insecticidal activity. A unique trihydroxylated hydrazone was active against both organisms, while another hydrazone, the most potent fungicide in this series, exhibited insecticidal activity only upon com- plexation with Zn2+ ions.
authors.forename: M R E
authors.initials: MR
authors.lastname: Aly
authors.forename: M M
authors.initials: MM
authors.lastname: Ibrahim
authors.forename: A M
authors.initials: AM
authors.lastname: Okael
authors.forename: Y A M H
authors.initials: YA
authors.lastname: Gherbawy
mesh_terms: D000818:Animals; D005659:Fungicides, Industrial / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D005670:Fusarium / Q000187:drug effects; D006835:Hydrazones / Q000737:chemistry; D007306:Insecticides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011720:Pyrazoles / Q000737:chemistry; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D048889:Weevils / Q000187:drug effects
chemical_list: D005659:Fungicides, Industrial; D006835:Hydrazones; D007306:Insecticides; D011720:Pyrazoles; D011804:Quinolines; C037219:quinoline