title: Study of the risk factors and complications of diabetes mellitus after live kidney donation.
abstract: OBJECTIVE
  Kidney donors, similar to the general population, are at risk for development of type 2 diabetes mellitus. The course of donors who develop type 2 diabetes mellitus has not been well studied. This work is aimed at estimating the incidence of diabetes after kidney donation, and study some risk factors and some complications of diabetes mellitus after donation.
  
  
  METHODS
  The material of this record based work comprised the records 2267 donors who donated 1 of their kidneys between 1976 and 2014 in the Urology and Nephrology Center, Mansoura University, Egypt, and regularly followed-up at its outpatient clinic. There were 388 donors included in the study and their medical records were revised.
  
  
  RESULTS
  Postdonation weight gain and family history of diabetes mellitus were statistically significant on both the development of diabetes mellitus, high, very high albuminuria, and/or decreased creatinine clearance. Metformin and insulin use seemed to significantly reduce the protein excretion, and creatinine clearance decline in the studied group.
  
  
  CONCLUSIONS
  There is a significant effect of the family history of diabetes mellitus on the development of high, very high albuminuria, and/or decreased creatinine clearance.
authors.affiliation: From the Mansoura Urology and Nephrology Center, Egypt.
authors.forename: Mohammed M
authors.initials: MM
authors.lastname: Abuelmagd
authors.forename: Ayman M
authors.initials: AM
authors.lastname: Nagib
authors.forename: Megahed M
authors.initials: MM
authors.lastname: Abuelmagd
authors.forename: Ayman F
authors.initials: AF
authors.lastname: Refaie
authors.forename: Yasser A
authors.initials: YA
authors.lastname: Elhindi
authors.forename: Mohammed F
authors.initials: MF
authors.lastname: Ahmed
authors.forename: Mohammed H
authors.initials: MH
authors.lastname: Ali
authors.forename: Hanzada M
authors.initials: HM
authors.lastname: Elmaghrabi
authors.forename: Mohammed A
authors.initials: MA
authors.lastname: Bakr
mesh_terms: D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000175:diagnosis / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D003928:Diabetic Nephropathies / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D004534:Egypt / Q000453:epidemiology; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D015994:Incidence; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000379:methods; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000009:adverse effects*; D011379:Prognosis; D012307:Risk Factors; D013997:Time Factors; D015430:Weight Gain
chemical_list: D007004:Hypoglycemic Agents