title: Comparison of recovery profile for propofol and sevoflurane anesthesia in cases of open cholecystectomy.
abstract: OBJECTIVE
  Sevoflurane and propofol are considered to be the agents of choice in surgeries of short duration due to their better recovery profile and few post-operative complications. This study was designed to compare the early recovery profile of sevoflurane and propofol anesthesia in patients undergoing open cholecystectomy.
  
  
  METHODS
  A total of 60 patients of either sex with American Society of Anesthesiologists grade 1 and 2 scheduled for elective cholecystectomy were prospectively randomized into two groups. Group S (30 patients) were maintained with sevoflurane anesthesia (1-2%), while in Group P (30 patients) were maintained with propofol infusion (75-125 μg/kg/min) in both the groups the anesthetic concentration/dose was so adjusted to keep hemodynamic parameter (mean arterial pressure and heart rate) within 15% of their respective baselines values.
  
  
  RESULTS
  It was observed that there was no significant difference (P > 0.05) between there early recovery profile that includes spontaneous eye opening (7.5 ± 1.6 min for sevoflurane group and 6.9 ± 1.7 min for propofol group), following simple verbal command (9.2 ± 2.2 min for sevoflurane group and 8.9 ± 1.9 min for propofol group) and extubation time (10.7 ± 2.3 min for sevoflurane group and 10.3 ± 2.0 min for propofol group) but there was a significant difference (P < 0.05) in incidence of post-operative nausea and vomiting (PONV) in both groups.
  
  
  CONCLUSIONS
  Propofol is as good as sevoflurane for maintenance of anesthesia in surgeries like open cholecystectomy with an added advantage of lower incidence of PONV owing to its intrinsic antiemetic properties.
authors.affiliation: Department of Anaesthesiology, S.H.K.M., Government Medical College, Nalhar, District Mewat, Haryana, India.
authors.forename: Shiv Kumar
authors.initials: SK
authors.lastname: Singh
authors.affiliation: Department of Anaesthesiology, S.H.K.M., Government Medical College, Nalhar, District Mewat, Haryana, India.
authors.forename: Amit
authors.initials: A
authors.lastname: Kumar
authors.affiliation: Department of Anaesthesiology, S.H.K.M., Government Medical College, Nalhar, District Mewat, Haryana, India.
authors.forename: Reena
authors.initials: R
authors.lastname: Mahajan
authors.affiliation: Department of OBG, S.H.K.M., Government Medical College, Nalhar, District Mewat, Haryana, India.
authors.forename: Surabhi
authors.initials: S
authors.lastname: Katyal
authors.affiliation: Department of Medicine, S.H.K.M., Government Medical College, Nalhar, District Mewat, Haryana, India.
authors.forename: Sfurti
authors.initials: S
authors.lastname: Mann
keywords: Cholecystectomy; propofol; recovery profile; sevoflurane