title: Comparison of PET with PET/CT in detecting peritoneal carcinomatosis: a meta-analysis.
abstract: OBJECTIVE
  The study aims to perform a meta-analysis to compare the diagnostic value of FDG PET with PET/CT in detecting peritoneal carcinomatosis (PC) to identify the potentially most useful diagnostic modality.
  
  
  METHODS
  A computer-aided search was performed in the Cochrane Library, PubMed, EMBASE, Web of Science, the China Biological Medicine Database, VIP, China National Knowledge Infrastructure database, and Wanfang databases for articles concerning diagnosis of peritoneal metastases with PET or PET/CT. QUADAS was used to evaluate the included articles' quality.
  
  
  RESULTS
  On a per-patient basis, the pooled sensitivity of PET/CT (84%) was significantly higher than that of PET (60%), and the pooled specificity of PET (98%) was markedly higher than that for PET/CT (94%). On a per-lesion basis, the pooled sensitivity and specificity of PET/CT were 87 and 95%, respectively. Only 1 PET study on a per-lesion basis, its sensitivity is 65.8 and specificity is 94.1%.
  
  
  CONCLUSIONS
  PET and PET/CT are powerful imaging techniques for detection and characterization of PC. PET/CT can be used as a screening tool and it may be acceptable to use PET as a diagnosis tool.
authors.affiliation: The First Clinical Medical School of Lanzhou University, Lanzhou, Gansu, China.
authors.forename: Jinkui
authors.initials: J
authors.lastname: Li
authors.affiliation: The First Clinical Medical School of Lanzhou University, Lanzhou, Gansu, China.
authors.forename: Ruifeng
authors.initials: R
authors.lastname: Yan
authors.affiliation: The First Hospital of Lanzhou Univesity, Lanzhou, Gansu, China. leijq1990@163.com.
authors.forename: Junqiang
authors.initials: J
authors.lastname: Lei
authors.affiliation: The First Clinical Medical School of Lanzhou University, Lanzhou, Gansu, China.
authors.forename: Changqin
authors.initials: C
authors.lastname: Jiang
mesh_terms: D002277:Carcinoma / Q000175:diagnosis*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D064847:Multimodal Imaging; D010534:Peritoneal Neoplasms / Q000175:diagnosis*; D010537:Peritoneum / Q000000981:diagnostic imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Meta-analysis; PET; PET/CT; Peritoneal carcinomatosis; Positron emission tomography