title: Late Presentation of Enlarging Lower Eyelid Mass and Muscle Degeneration Secondary to Hyaluronic Acid Filler.
abstract: A 66-year-old female presented for evaluation of progressively worsening edema and palpable masses in both lower eyelids. While she denied prior filler to the lower eyelid or tear trough, histopathology revealed degenerating striated muscle surrounding pools of hyaluronic acid. While cases of gradually enlarging masses associated with facial filler placement have been reported, there is no literature identifying muscle degeneration adjacent to hyaluronic acid filler.
authors.affiliation: *Department of Ophthalmology, †Department of Ophthalmology and Pathology, and ‡Department of Ophthalmology and Otolaryngology, University of Minnesota, Minneapolis, Minnesota, U.S.A.
authors.forename: Alison A
authors.initials: AA
authors.lastname: Teo
authors.forename: Ali
authors.initials: A
authors.lastname: Mokhtarzadeh
authors.forename: J Douglas
authors.initials: JD
authors.lastname: Cameron
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Harrison
mesh_terms: D000368:Aged; D001706:Biopsy; D003357:Cosmetic Techniques / Q000009:adverse effects*; D005141:Eyelid Diseases / Q000139:chemically induced* / Q000175:diagnosis; D005143:Eyelids / Q000187:drug effects / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000009:adverse effects*; D007279:Injections, Subcutaneous; D009801:Oculomotor Muscles / Q000187:drug effects / Q000473:pathology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D055675:Viscosupplements / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D055675:Viscosupplements; D006820:Hyaluronic Acid