title: Optional Endoreplication and Selective Elimination of Parental Genomes during Oogenesis in Diploid and Triploid Hybrid European Water Frogs.
abstract: Incompatibilities between parental genomes decrease viability of interspecific hybrids; however, deviations from canonical gametogenesis such as genome endoreplication and elimination can rescue hybrid organisms. To evaluate frequency and regularity of genome elimination and endoreplication during gametogenesis in hybrid animals with different ploidy, we examined genome composition in oocytes of di- and triploid hybrid frogs of the Pelophylax esculentus complex. Obtained results allowed us to suggest that during oogenesis the endoreplication involves all genomes occurring before the selective genome elimination. We accepted the hypothesis that only elimination of one copied genome occurs premeiotically in most of triploid hybrid females. At the same time, we rejected the hypothesis stating that the genome of parental species hybrid frogs co-exist with is always eliminated during oogenesis in diploid hybrids. Diploid hybrid frogs demonstrate an enlarged frequency of deviations in oogenesis comparatively to triploid hybrids. Typical for hybrid frogs deviations in gametogenesis increase variability of produced gametes and provide a mechanism for appearance of different forms of hybrids.
authors.affiliation: Saint-Petersburg State University, Saint-Petersburg, Russia.
authors.forename: Dmitry
authors.initials: D
authors.lastname: Dedukh
authors.affiliation: Institute of Cytology, Russian Academy of Sciences, Saint-Petersburg, Russia.
authors.forename: Spartak
authors.initials: S
authors.lastname: Litvinchuk
authors.affiliation: Institute of Cytology, Russian Academy of Sciences, Saint-Petersburg, Russia.
authors.forename: Juriy
authors.initials: J
authors.lastname: Rosanov
authors.affiliation: Department of Ecology and Genetic, Evolutionary Biology Centre, Uppsala University, Uppsala, Sweden; V.N. Karazin Kharkiv National University, Kharkiv, Ukraine.
authors.forename: Glib
authors.initials: G
authors.lastname: Mazepa
authors.affiliation: Saint-Petersburg State University, Saint-Petersburg, Russia.
authors.forename: Alsu
authors.initials: A
authors.lastname: Saifitdinova
authors.affiliation: V.N. Karazin Kharkiv National University, Kharkiv, Ukraine.
authors.forename: Dmitry
authors.initials: D
authors.lastname: Shabanov
authors.affiliation: Saint-Petersburg State University, Saint-Petersburg, Russia.
authors.forename: Alla
authors.initials: A
authors.lastname: Krasikova
mesh_terms: D000818:Animals; D001483:Base Sequence; D002875:Chromosomes / Q000235:genetics; D004171:Diploidy; D062951:Endoreduplication / Q000235:genetics*; D005260:Female; D016678:Genome; D005838:Genotype; D006824:Hybridization, Genetic; D009865:Oocytes / Q000378:metabolism; D009866:Oogenesis / Q000235:genetics*; D011898:Ranidae / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics; D057885:Triploidy; D014867:Water
chemical_list: D014867:Water