title: Bed rest for preventing complications after transfemoral cardiac catheterisation: a protocol of systematic review and network meta-analysis.
abstract: BACKGROUND
  Transfemoral cardiac catheterisation is an invasive medical procedure used for therapeutic or diagnostic purposes. Postoperative bed rest can prevent a number of complications such as bleeding and haematoma formation and can result in side effects such as back pain and urinary discomfort. Currently, there is no consensus regarding the optimal length of bed rest. Our objective is to assess the effects of post-catheterisation length of bed rest on bleeding and haematoma, other vascular complications, patient symptoms and patient discomfort, among patients who underwent transfemoral cardiac catheterisation.
  
  
  METHODS
  We wrote this protocol in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols statement. We defined the search query by using the PICO framework (Population: Patients undergoing cardiac catheterisation;
  
  
  METHODS
  early mobilisation; Comparison: late mobilisation;
  
  
  RESULTS
  early and late complications). We will search six biomedical databases and five online registries to obtain both published and unpublished studies. We will include randomised controlled trials and quasi-randomised controlled trials, and their quality will be independently appraised with the Cochrane Effective Practice and Organisation of Care criteria for quality assessment. We will carry out a pairwise meta-analysis and network meta-analysis to estimate the overall intervention effects from both direct and indirect comparisons.
  
  
  CONCLUSIONS
  This review may have considerable implications for practice and help to achieve an effective and efficient management of patients who underwent cardiac catheterisation. This review will be grounded in an expanded search of 11 resources and will employ innovative statistical methods such as network meta-analysis.
  
  
  BACKGROUND
  PROSPERO registration number: CRD42014014222 .
authors.affiliation: School of Nursing, Biella Hospital, Corso Pella 10, 13900, Biella, Italy. alberto.dalmolin@gmail.com.|Department of Translational Medicine, Università del Piemonte Orientale, Via Salaroli 17, 28100, Novara, Italy. alberto.dalmolin@gmail.com.
authors.forename: Alberto
authors.initials: A
authors.lastname: Dal Molin
authors.affiliation: Department of Translational Medicine, Università del Piemonte Orientale, Via Salaroli 17, 28100, Novara, Italy. fabrizio.faggiano@med.unipmn.it.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Faggiano
authors.affiliation: Internal Medicine, Ospedale degli Infermi, Via Dei Ponderanesi 2, 13875, Ponderano - Biella, Italy. fabio.bertoncini@hotmail.it.
authors.forename: Fabio
authors.initials: F
authors.lastname: Bertoncini
authors.affiliation: Nursing Home 'Villa Poma', Viale della Rimembranza 7, 13816, Miagliano, Biella, Italy. giulia.buratti@libero.it.
authors.forename: Giulia
authors.initials: G
authors.lastname: Buratti
authors.affiliation: Inpatient Neonatology/Neonatal Intensive Care Unit, Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino, Ospedale Ostetrico Ginecologico S.Anna, Corso Spezia 60, 10126, Torino, Italy. ebusca89@gmail.com.
authors.forename: Erica
authors.initials: E
authors.lastname: Busca
authors.affiliation: Semi Intensive Medicine and Nephrology, Ospedale degli Infermi, Via Dei Ponderanesi 2, 13875, Ponderano - Biella, Italy. casarotto.roberta@libero.it.
authors.forename: Roberta
authors.initials: R
authors.lastname: Casarotto
authors.affiliation: Emergency Room, Ospedale degli Infermi, Via Dei Ponderanesi 2, 13875, Ponderano - Biella, Italy. samanta.gaboardi@fastwebnet.it.
authors.forename: Samanta
authors.initials: S
authors.lastname: Gaboardi
authors.affiliation: Department of Translational Medicine, Università del Piemonte Orientale, Via Salaroli 17, 28100, Novara, Italy. elias.allara@unito.it.|School of Public Health, University of Torino, Via Santena 5 bis, 10126, Torino, Italy. elias.allara@unito.it.
authors.forename: Elias
authors.initials: E
authors.lastname: Allara
mesh_terms: D001510:Bed Rest; D006328:Cardiac Catheterization / Q000009:adverse effects*; D002318:Cardiovascular Diseases; D002985:Clinical Protocols; D005269:Femur; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control*; D012107:Research Design; D000078202:Systematic Reviews as Topic; D015201:Meta-Analysis as Topic