title: Eccrine Angiomatous Hamartoma: A Clinicopathological Study of 26 Cases.
abstract: BACKGROUND
  Eccrine angiomatous hamartoma (EAH) is a rare benign cutaneous tumor characterized by the proliferation of eccrine glands and capillaries.
  
  
  OBJECTIVE
  The aim of this study was to summarize the clinicopathological characteristics of EAH.
  
  
  METHODS
  A retrospective chart review was performed on all patients diagnosed with EAH from 1977 to 2012 in the Union Hospital, Wuhan, P.R. China, and the clinicopathological features were compared with the cases reported in the literature.
  
  
  RESULTS
  A total of 26 patients with EAH were identified. The male:female ratio was 1.2:1. EAH most commonly presents as a solitary (80.8%) plaque (50.0%) on the lower extremities (61.5%). Most patients presented with hyperhidrosis localizing to the lesion. Although most patients did not have major pain or anatomic deformity, one patient had severe pain as well as difficulty walking and moving, necessitating leg amputation. The histopathological findings showed typical features of EAH.
  
  
  CONCLUSIONS
  EAH is a rare but characteristically benign skin hamartomatous condition. In rare occasions it can be associated with severe structural and functional impairment.
authors.affiliation: Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China.
authors.forename: Tutyana
authors.initials: T
authors.lastname: Sanusi
authors.forename: Yanqiu
authors.initials: Y
authors.lastname: Li
authors.forename: Lan
authors.initials: L
authors.lastname: Sun
authors.forename: Chunsen
authors.initials: C
authors.lastname: Wang
authors.forename: Youwen
authors.initials: Y
authors.lastname: Zhou
authors.forename: Changzheng
authors.initials: C
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D002196:Capillaries / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D004439:Eccrine Glands / Q000473:pathology*; D005260:Female; D006222:Hamartoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D006945:Hyperhidrosis / Q000209:etiology; D007223:Infant; D007231:Infant, Newborn; D035002:Lower Extremity; D008297:Male; D010146:Pain / Q000209:etiology; D012189:Retrospective Studies; D013544:Sweat Gland Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery