title: A modular, air-stable nickel precatalyst.
abstract: The synthesis and catalytic activity of [(TMEDA)Ni(o-tolyl)Cl], an air-stable, crystalline solid, is described. This complex is an effective precatalyst in a variety of nickel-catalyzed transformations. The lability of TMEDA allows a wide variety of ligands to be used, including mono- and bidentate phosphines, diimines, and N-heterocyclic carbenes. Preliminary mechanistic studies are also reported, which suggest that [(TMEDA)Ni(o-tolyl)Cl] can activate by either a Ni-B or Ni-Ni transmetalation event, depending on the reaction conditions.
authors.affiliation: Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
authors.forename: Jason D
authors.initials: JD
authors.lastname: Shields
authors.affiliation: Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
authors.forename: Erin E
authors.initials: EE
authors.lastname: Gray
authors.affiliation: Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.
authors.forename: Abigail G
authors.initials: AG
authors.lastname: Doyle
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D018360:Crystallography, X-Ray; D008024:Ligands; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D008968:Molecular Conformation; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry
chemical_list: D008024:Ligands; D009942:Organometallic Compounds; D010720:Phosphines; C030011:carbene; D009532:Nickel; D008697:Methane