title: Indium-catalyzed oxidative cross-dehydrogenative coupling of chromenes with 1,3-dicarbonyls and aryl rings.
abstract: An effective indium-catalyzed oxidative cross-dehydrogenative coupling of electronically varied chromenes with 1,3-dicarbonyl compounds and aryl rings has been established. Both the C-H alkylation and arylation proceed smoothly at room temperature to afford diverse α-substituted chromene compounds in up to 91% yields. Besides these two types of C-H components, simple ketones like cyclohexanones also prove to be well tolerated.
authors.affiliation: Key Lab of Chemical Biology of Ministry of Education, School of Pharmaceutical Sciences, Jinan 250012, P. R. China. leiliu@sdu.edu.cn.
authors.forename: Fanmei
authors.initials: F
authors.lastname: Li
authors.forename: Zhilin
authors.initials: Z
authors.lastname: Meng
authors.forename: Jing
authors.initials: J
authors.lastname: Hua
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Hongxiang
authors.initials: H
authors.lastname: Lou
authors.forename: Lei
authors.initials: L
authors.lastname: Liu
mesh_terms: D000478:Alkylation; D001578:Benzopyrans / Q000737:chemistry*; D002384:Catalysis; D003512:Cyclohexanones / Q000737:chemistry*; D007204:Indium / Q000494:pharmacology*; D015394:Molecular Structure; D058451:Oxidative Coupling; D010165:Palladium / Q000737:chemistry
chemical_list: D001578:Benzopyrans; D003512:Cyclohexanones; D007204:Indium; D010165:Palladium