title: Copper-catalyzed cascade addition/cyclization: highly efficient access to phosphonylated quinoline-2,4(1H,3H)-diones.
abstract: A novel and facile Cu-catalyzed addition/cyclization cascade of o-cyanoarylacrylamide was developed. The process exhibits significant functional group tolerance, and provides an efficient and straightforward pathway for the synthesis of various phosphonylated quinoline-2,4(1H,3H)-diones.
authors.affiliation: Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, P. R. China. liym@kmust.edu.cn.
authors.forename: Ya-Min
authors.initials: YM
authors.lastname: Li
authors.forename: Shi-Sheng
authors.initials: SS
authors.lastname: Wang
authors.forename: Fuchao
authors.initials: F
authors.lastname: Yu
authors.forename: Yuehai
authors.initials: Y
authors.lastname: Shen
authors.forename: Kwen-Jen
authors.initials: KJ
authors.lastname: Chang
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D005609:Free Radicals / Q000737:chemistry; D010757:Phosphorous Acids / Q000737:chemistry*; D011804:Quinolines / Q000737:chemistry*
chemical_list: D005609:Free Radicals; D010757:Phosphorous Acids; D011804:Quinolines; C570063:phosphonic acid; D003300:Copper; C037219:quinoline