title: The association of neutrophil to lymphocyte ratio and TIMI frame count in primary percutaneous coronary intervention.
abstract: BACKGROUND
  This study was sought to evaluate the relationship between admission neutrophil lymphocyte ratio (NLR) and estimated coronary flow by the TIMI frame count (TFC) method in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI).
  
  
  METHODS
  TFC of 262 consecutive STEMI patients were evaluated after PPCI. Admission NLR were calculated and TFC was determined after PPCI. According to admission NLR value, patients were divided in to two groups. NLR levels higher than 3.5 were defined "higher NLR" whereas lower than 3.5 were accepted as "lower NLR".
  
  
  RESULTS
  TFC was significantly higher in patients with higher NLR (56.6±41.1 vs. 37.9±36.1, P<0.001). No-reflow phenomenon was more frequent in higher NLR group compared to lower NLR group (10.1% vs. 5.2%, P=0.001). In multivariate linear regression analysis admission NLR was an independent predictor of high TIMI frame count (B=2.24 95 % CI (1.17-3.31), P<0.001).
  
  
  CONCLUSIONS
  Our findings suggest that admission NLR predicts coronary blood flow in means of TFC.
authors.affiliation: Department of Cardiology, Istanbul University Institute of Cardiology, Instanbul, Turkey - cuneytkocas@hotmail.com.
authors.forename: Cuneyt
authors.initials: C
authors.lastname: Kocas
authors.affiliation: Department of Cardiology, Istanbul University Institute of Cardiology, Instanbul, Turkey.
authors.forename: Okay
authors.initials: O
authors.lastname: Abaci
authors.affiliation: Department of Cardiology, Istanbul University Institute of Cardiology, Instanbul, Turkey.
authors.forename: Sukru
authors.initials: S
authors.lastname: Arslan
authors.affiliation: Department of Cardiology, Istanbul University Institute of Cardiology, Instanbul, Turkey.
authors.forename: Cem
authors.initials: C
authors.lastname: Bostan
authors.affiliation: Department of Cardiology, Istanbul University Institute of Cardiology, Instanbul, Turkey.
authors.forename: Ugur
authors.initials: U
authors.lastname: Coskun
authors.affiliation: Department of Cardiology, Mehmet Akif Ersoy State Hospital, Instanbul, Turkey.
authors.forename: Faruk
authors.initials: F
authors.lastname: Akturk
authors.affiliation: Department of Cardiology, Istanbul University Institute of Cardiology, Instanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Yildiz
authors.affiliation: Department of Cardiology, Istanbul University Institute of Cardiology, Instanbul, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Ersanli
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism*; D054318:No-Reflow Phenomenon / Q000453:epidemiology; D062645:Percutaneous Coronary Intervention / Q000379:methods*; D012189:Retrospective Studies; D000072657:ST Elevation Myocardial Infarction / Q000503:physiopathology / Q000628:therapy*