title: ﻿﻿﻿﻿﻿﻿Treatment of Fournier's Gangrene With a Novel Negative Pressure Wound Therapy System ﻿.
abstract: ﻿﻿﻿﻿﻿﻿﻿﻿﻿﻿Fournier's gangrene (FG) is a complex condition that requires surgical debridement, hemodynamic support, antibiotics, and appro- priate wound management. This study is the first to assess the use of a low-vacuum negative pressure wound therapy (LV-NPWT) system with low-adherent contact surface in two cases of FG.
  
  
  METHODS
  The protocol-of-care included twice weekly dressing changes and irrigation with a povidone-iodine-water mixture. Assessments included wound progression (% granulation tissue), ratings of dressing ingrowth, pain during treatment and at dressing changes, patient comfort, and ease- of-use.
  
  
  RESULTS
  A 51-year-old man (Patient A) developed FG after sur- gical removal of a perianal abscess. He received 16 days of LV-NPWT with five dressing changes. A 64-year-old man (Patient B) with multiple comorbidities, developed FG after traumatic injury. He received 20 days of LV-NPWT with six dressing changes. In both patients, LV-NPWT promoted rapid granulation tissue formation. Pain scores averaged low-to-moderate during treatment and dressing changes, and tissue ingrowth was minimal.
  
  
  CONCLUSIONS
  Overall, ratings were favorable for LV-NPWT ease-of-use and patient comfort. Despite the complexity of these wounds, with the use of LV-NPWT, both wounds progressed to a point where they were able to successfully receive surgical closure with skin grafts and/or flaps. These cases may suggest that LV-NPWT may have a potential role in complex wound management.
authors.affiliation: ﻿﻿Department of Plastic and Reconstructive Surgery, Wound Healing and Tissue Engineering Unit, Gent University Hospital, Gent, Belgium.
authors.forename: Jozef
authors.initials: J
authors.lastname: Verbelen
authors.affiliation: Department of Plastic and Reconstructive Surgery, Wound Healing and Tissue Engineering Unit, Gent University Hospital, Gent, Belgium.
authors.forename: Henk
authors.initials: H
authors.lastname: Hoeksema
authors.affiliation: Department of Plastic and Reconstructive Surgery, Wound Healing and Tissue Engineering Unit, Gent University Hospital, Gent, Belgium.
authors.forename: Alexander
authors.initials: A
authors.lastname: Heyneman
authors.affiliation: Department of Plastic and Reconstructive Surgery, Wound Healing and Tissue Engineering Unit, Gent University Hospital, Gent, Belgium.
authors.forename: Ali
authors.initials: A
authors.lastname: Pirayesh
authors.affiliation: Department of Plastic and Reconstructive Surgery, Wound Healing and Tissue Engineering Unit, Gent University Hospital, Gent, Belgium; E-mail: Stan.monstrey@ugent.be.
authors.forename: Stan
authors.initials: S
authors.lastname: Monstrey