title: Sleep electroencephalography and heart rate variability interdependence amongst healthy subjects and insomnia/schizophrenia patients.
abstract: The quantification of interdependencies within autonomic nervous system has gained increasing importance to characterise healthy and psychiatric disordered subjects. The present work introduces a biosignal processing approach, suggesting a computational resource to estimate coherent or synchronised interactions as an eventual supportive aid in the diagnosis of primary insomnia and schizophrenia pathologies. By deploying linear, nonlinear and statistical methods upon 25 electroencephalographic and electrocardiographic overnight sleep recordings, the assessment of cross-correlation, wavelet coherence and [Formula: see text]:[Formula: see text] phase synchronisation is focused on tracking discerning features amongst the clinical cohorts. Our results indicate that certain neuronal oscillations interact with cardiac power bands in distinctive ways responding to standardised sleep stages and patient groups, which promotes the hypothesis of subtle functional dynamics between neuronal assembles and (para)sympathetic activity subject to pathophysiological conditions.
authors.affiliation: School of Electrical and Computing Engineering, RMIT University, Melbourne, VIC, 3121, Australia. s3361953@student.rmit.edu.au.
authors.forename: Ramiro
authors.initials: R
authors.lastname: Chaparro-Vargas
authors.affiliation: Sleep laboratory of the Central Institute of Mental Health, Mannheim, Germany. claudia.schilling@zi-mannheim.de.
authors.forename: Claudia
authors.initials: C
authors.lastname: Schilling
authors.affiliation: Sleep laboratory of the Central Institute of Mental Health, Mannheim, Germany. michael.schredl@zi-mannheim.de.
authors.forename: Michael
authors.initials: M
authors.lastname: Schredl
authors.affiliation: School of Electrical and Computing Engineering, RMIT University, Melbourne, VIC, 3121, Australia. dean.cvetkovic@rmit.edu.au.
authors.forename: Dean
authors.initials: D
authors.lastname: Cvetkovic
mesh_terms: D016022:Case-Control Studies; D004569:Electroencephalography; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000503:physiopathology*; D012890:Sleep / Q000502:physiology*; D007319:Sleep Initiation and Maintenance Disorders / Q000503:physiopathology*
keywords: EEG; HRV; Phase locking value; Phase synchronisation; Primary insomnia; Schizophrenia; Wavelet coherence