title: A colorimetric sensor for the sequential detection of Cu(2+) and CN(-) in fully aqueous media: practical performance of Cu(2+).
abstract: A new highly selective colorimetric chemosensor 1 (E)-9-(((5-mercapto-1,3,4-thiadiazol-2-yl)imino)methyl)-2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-8-ol was designed and synthesized for the sequential detection of Cu(2+) and CN(-). This sensor 1 exhibited an obvious color change from yellow to orange in the presence of Cu(2+) in a fully aqueous solution. The detection limit (0.9 μM) of 1 for Cu(2+) is far lower than the WHO limit (31.5 μM) for drinking water. In addition, the resulting Cu(2+)-2· 1 complex can be further used to detect toxic cyanide through a color change from orange to yellow, indicating the recovery of 1 from Cu(2+)-2·1. Importantly, chemosensor 1 could be used to detect and quantify Cu(2+) in water samples, and a colorimetric test strip of 1 for the detection of Cu(2+) could be useful for all practical purposes.
authors.affiliation: Department of Fine Chemistry and Department of Interdisciplinary Bio IT Materials, Seoul National University of Science and Technology, Seoul 139-743, Korea. chealkim@seoultech.ac.kr.
authors.forename: Ga Rim
authors.initials: GR
authors.lastname: You
authors.forename: Gyeong Jin
authors.initials: GJ
authors.lastname: Park
authors.forename: Jae Jun
authors.initials: JJ
authors.lastname: Lee
authors.forename: Cheal
authors.initials: C
authors.lastname: Kim
mesh_terms: D003124:Colorimetry / Q000295:instrumentation; D004396:Coloring Agents / Q000138:chemical synthesis / Q000737:chemistry*; D003300:Copper / Q000032:analysis*; D003486:Cyanides / Q000032:analysis*; D015394:Molecular Structure; D015125:Oxyquinoline / Q000138:chemical synthesis / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: C000604610:9-(((5-mercapto-1,3,4-thiadiazol-2-yl)imino)-methyl)-2,3,6,7-tetrahydro-1H,5H-pyrido(3,2,1-ij)quinolin-8-ol; D004396:Coloring Agents; D003486:Cyanides; D011725:Pyridines; D014867:Water; D015125:Oxyquinoline; D003300:Copper