title: Association of copeptin and cortisol in newly diagnosed multiple sclerosis patients.
abstract: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system. Obesity may increase the risk of developing MS. The aim of this study was to evaluate copeptin and cortisol plasma levels in newly diagnosed untreated MS patients and to determine whether copeptin and cortisol are related to the patients' clinical statuses. We report that copeptin and cortisol were higher in overweight/obese MS patients. Positive correlations were observed between the two parameters. We conclude that alterations of copeptin and cortisol levels in multiple sclerosis patients may be related to adiposity. An increase in cortisol may also be associated with copeptin secretion.
authors.affiliation: Department of Endocrinology, Centre of Postgraduate Medical Education, Bielanski Hospital, Ceglowska 80, 01-809 Warsaw, Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Baranowska-Bik
authors.affiliation: Department of Neurology, Medical University of Warsaw, Bielanski Hospital, Ceglowska 80, 01-809 Warsaw, Poland.
authors.forename: Jan
authors.initials: J
authors.lastname: Kochanowski
authors.affiliation: Department of Neurology, Medical University of Warsaw, Bielanski Hospital, Ceglowska 80, 01-809 Warsaw, Poland.
authors.forename: Dorota
authors.initials: D
authors.lastname: Uchman
authors.affiliation: Department of Neuroendocrinology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Litwiniuk
authors.affiliation: Department of Neuroendocrinology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland.
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Kalisz
authors.affiliation: Department of Neuroendocrinology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland.
authors.forename: Lidia
authors.initials: L
authors.lastname: Martynska
authors.affiliation: Department of Neuroendocrinology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland.
authors.forename: Ewa
authors.initials: E
authors.lastname: Wolinska-Witort
authors.affiliation: Department of Neurology, Medical University of Warsaw, Bielanski Hospital, Ceglowska 80, 01-809 Warsaw, Poland.
authors.forename: Boguslawa
authors.initials: B
authors.lastname: Baranowska
authors.affiliation: Department of Neuroendocrinology, Centre of Postgraduate Medical Education, Marymoncka 99/103, 01-813 Warsaw, Poland. Electronic address: wojtmed@wp.pl.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Bik
mesh_terms: D050154:Adiposity / Q000502:physiology; D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D004185:Disability Evaluation; D005260:Female; D006020:Glycopeptides / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D013223:Statistics as Topic; D018709:Statistics, Nonparametric; D062685:Steatocystoma Multiplex / Q000097:blood*; D055815:Young Adult
chemical_list: D006020:Glycopeptides; C048197:copeptins; D006854:Hydrocortisone
keywords: Adiposity; Copeptin; Cortisol; Multiple sclerosis