title: The treatment of haematemesis and upper gastrointestinal bleeding in United Kingdom Armed Forces and other deployed units.
abstract: BACKGROUND
  Upper Gastro-intestinal (UGI) bleeding is a significant cause of morbidity worldwide. United Kingdom Armed Forces (UKAFs) are not immune to this condition. There is a substantial body of conflicting evidence regarding initial management and risk stratification.
  
  
  OBJECTIVE
  To provide the background knowledge and treatment pathways required to assess and manage a patient adequately during the first 24 hours of an episode of UGI bleeding.
  
  
  RESULTS
  Clinical grading of hypovolaemic shock is inaccurate, but is a broad indicator of severity; the Rockall Score must not be used to assess requirement for intervention. Where laboratory assets are available, the Blatchford score is adequate to assess requirements for intervention.
  
  
  RESULTS
  The principles of hypotensive resuscitation (target systolic blood pressure 90 mmHg for the first hour) hold true for UGI bleeds. In areas where endoscopy is available within four hours, a restrictive pattern of packed Red Blood Cell (pRBC) transfusion may be beneficial. Despite limited evidence of benefit, Proton Pump Inhibitors (PPIs) should be given routinely in UKAFs. Where available, in cases of variceal and non-variceal UGI Haemorrhage without locally available endoscopy, administration of tranexamic acid and somatostatin or octreotide should be considered.
authors.forename: R
authors.initials: R
authors.lastname: Arr Woodward
authors.forename: M
authors.initials: M
authors.lastname: Khan
mesh_terms: D016099:Endoscopy, Gastrointestinal; D006471:Gastrointestinal Hemorrhage / Q000209:etiology* / Q000628:therapy*; D006396:Hematemesis / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D008889:Military Personnel; D012307:Risk Factors; D012769:Shock / Q000209:etiology / Q000628:therapy; D006113:United Kingdom; D055986:Vital Signs