title: Diagnostic evaluation for nontraumatic intracerebral hemorrhage.
abstract: Intracerebral hemorrhage (ICH) is a devastating condition with multiple possible underlying causes. Early diagnosis of ICH associated with a precise diagnostic work-up is mandatory. Clinical signs may give clues to diagnosis but are not reliable enough and imaging remains the cornerstone of management. Noncontrast computed tomography and magnetic resonance imaging (MRI) are highly sensitive for ICH identification. Additionally, MRI may disclose brain parenchymal biomarkers that can contribute to the etiologic diagnosis. Vessel examination should be carried out whenever there is a clinical suspicion of underlying structural lesions, such as vascular malformations or tumors. To date, conventional angiography remains the gold standard to detect intracranial vascular malformations in patients with ICH.
authors.affiliation: Department of Neurology, University of Lille, UDSL, CHU Lille, Inserm U 1171, Lille 59000, France; CAPES Foundation, Ministry of Education, Quadra 2, Bloco L, Lote 06, Edifício Capes - CEP: 70.040-020 - Brasilia-DF, Brazil.
authors.forename: Renan
authors.initials: R
authors.lastname: Domingues
authors.affiliation: Department of Neurology, University of Lille, UDSL, CHU Lille, Inserm U 1171, Lille 59000, France.
authors.forename: Costanza
authors.initials: C
authors.lastname: Rossi
authors.affiliation: Department of Neurology, University of Lille, UDSL, CHU Lille, Inserm U 1171, Lille 59000, France. Electronic address: charlotte.cordonnier@chru-lille.fr.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Cordonnier
mesh_terms: D002543:Cerebral Hemorrhage / Q000175:diagnosis*; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D006801:Humans; D059906:Neuroimaging / Q000379:methods
keywords: Cerebral amyloid angiopathy; Deep perforating vasculopathy; Diagnostic evaluation; Digital subtraction angiography; Intracerebral hemorrhage; MRI