title: Overcoming entrenched disagreements: the case of misoprostol for post-partum haemorrhage.
abstract: The debate about whether misoprostol should be distributed to low resource communities to prevent post-partum haemorrhage (PPH), recognized as a major cause of maternal mortality, is deeply polarised. This is in spite of stakeholders having access to the same evidence about the risks and benefits of misoprostol. To understand the disagreement, we conducted a qualitative analysis of the values underpinning debates surrounding community distribution of misoprostol. We found that different moral priorities, epistemic values, and attitudes towards uncertainty were the main factors sustaining the debate. With this understanding, we present a model for ethical discourse that might overcome the current impasse.
authors.forename: Narcyz
authors.initials: N
authors.lastname: Ghinea
authors.forename: Wendy
authors.initials: W
authors.lastname: Lipworth
authors.forename: Miles
authors.initials: M
authors.lastname: Little
authors.forename: Ian
authors.initials: I
authors.lastname: Kerridge
authors.forename: Richard
authors.initials: R
authors.lastname: Day
mesh_terms: D003906:Developing Countries / Q000191:economics / Q000706:statistics & numerical data; D034462:Dissent and Disputes; D019317:Evidence-Based Medicine; D005260:Female; D006297:Health Services Accessibility / Q000941:ethics*; D006801:Humans; D008428:Maternal Mortality; D016595:Misoprostol / Q000008:administration & dosage*; D010120:Oxytocics / Q000008:administration & dosage*; D006473:Postpartum Hemorrhage / Q000401:mortality / Q000517:prevention & control*; D011203:Poverty; D011247:Pregnancy; D036301:Qualitative Research; D012935:Social Justice; D035501:Uncertainty; D014944:World Health Organization
chemical_list: D010120:Oxytocics; D016595:Misoprostol