title: Photo-organocatalytic Enantioselective Perfluoroalkylation of β-Ketoesters.
abstract: The visible-light-driven, phase-transfer-catalyzed, enantioselective perfluoroalkylation and trifluoromethylation of cyclic β-ketoesters is described. The photo-organocatalytic process, which occurs at ambient temperature and under visible light illumination, is triggered by the photochemical activity of in situ-generated electron donor-acceptor complexes, arising from the association of chiral enolates and perfluoroalkyl iodides. Preliminary mechanistic studies are reported.
authors.affiliation: †ICIQ-Institute of Chemical Research of Catalonia, Av. Països Catalans 16, 43007 Tarragona, Spain.
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Woźniak
authors.affiliation: †ICIQ-Institute of Chemical Research of Catalonia, Av. Països Catalans 16, 43007 Tarragona, Spain.
authors.forename: John J
authors.initials: JJ
authors.lastname: Murphy
authors.affiliation: †ICIQ-Institute of Chemical Research of Catalonia, Av. Països Catalans 16, 43007 Tarragona, Spain.|‡ICREA-Catalan Institution for Research and Advanced Studies, Pg. Lluís Companys 23, 08010 Barcelona, Spain.
authors.forename: Paolo
authors.initials: P
authors.lastname: Melchiorre