title: First description of food-borne Salmonella enterica resistance regions R1 and R3 associated with IS26 elements.
abstract: In this study, we assessed the presence of IS26 in food-borne ASSuT-type Salmonella enterica isolates. A new genetic region (R3) was described, that included a C14 caspase gene between IS26 elements. R3 was present in two Salmonella Rissen isolates from a swine carcass and a meat handler, collected at the same abattoir. Furthermore, a new rearrangement of resistance region R1, harboring the blaTEM-1 gene flanked by IS26 elements, was identified in Salmonella Typhimurium and Salmonella 4,[5],12:i:-, from different samples. This study highlights the zoonotic potential of Salmonella spp. isolates and the possible role of IS26 in the mobilization of resistance genes.
authors.affiliation: ICBAS, Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Porto, Portugal; CECA-ICETA, Centro de Estudos de Ciência Animal, Universidade do Porto, Porto, Portugal. Electronic address: egomesneves@mail.icav.up.pt.
authors.forename: Eduarda
authors.initials: E
authors.lastname: Gomes-Neves
authors.affiliation: CECA-ICETA, Centro de Estudos de Ciência Animal, Universidade do Porto, Porto, Portugal; Departamento de Doenças Infeciosas, Instituto Nacional de Dr. Ricardo Jorge, Lisboa and Porto, Portugal. Electronic address: vera.manageiro@insa.min-saude.pt.
authors.forename: Vera
authors.initials: V
authors.lastname: Manageiro
authors.affiliation: Departamento de Doenças Infeciosas, Instituto Nacional de Dr. Ricardo Jorge, Lisboa and Porto, Portugal. Electronic address: eugenia.ferreira@insa.min-saude.pt.
authors.forename: Eugénia
authors.initials: E
authors.lastname: Ferreira
authors.affiliation: CECA-ICETA, Centro de Estudos de Ciência Animal, Universidade do Porto, Porto, Portugal; Departamento de Doenças Infeciosas, Instituto Nacional de Dr. Ricardo Jorge, Lisboa and Porto, Portugal. Electronic address: jose.costa@insa.min-saude.pt.
authors.forename: José M
authors.initials: JM
authors.lastname: Correia da Costa
authors.affiliation: Departamento de Doenças Infeciosas, Instituto Nacional de Dr. Ricardo Jorge, Lisboa and Porto, Portugal. Electronic address: manuela.canica@insa.min-saude.pt.
authors.forename: Manuela
authors.initials: M
authors.lastname: Caniça
mesh_terms: D000003:Abattoirs; D000818:Animals; D004251:DNA Transposable Elements; D024881:Drug Resistance, Bacterial; D005516:Food Microbiology; D006801:Humans; D012480:Salmonella Infections / Q000382:microbiology*; D019779:Salmonella enterica / Q000145:classification / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification*; D065288:Serogroup; D013552:Swine; D015047:Zoonoses / Q000382:microbiology
chemical_list: D004251:DNA Transposable Elements
keywords: IS26; Portugal; Salmonella spp.; Swine