title: [Complete genome characterization of the Kyzylagach virus (KYZV) (Togaviridae, Alphavirus, Sindbis serogroup) isolated from mosquitoes Culex modestus Ficalbi, 1889 (Culicinae) collected in a colony of herons (Ardeidae Leach, 1820) in Azerbaijan].
abstract: Complete genome sequencing of the Kyzylagach virus (KYZV) LEIV-65A strain isolated from the Culex modestus Ficalbi, 1889 (Culicinae), which was collected in the colony of the Ardeidae Leach, 1820 birds on the coast of Caspian sea, Kyzyl-Agach bay, in the southern part of Azerbaijan, was carried out. KYZV has high homology (about 99%) with the Chinese XJ-160 strain of the Sindbis virus (SINV) isolated from Anopheles sp. in Xinjiang Uyghur autonomic region (north-eastern China). Homologies of KYZV and XJ-160 with European SINV strains are 82% and 93% for the nucleotide and amino acid sequences, respectively (GenBank ID: KF981618). The difference between the nucleotide sequences of KYZV and Australian SINV/SW6562 strain is 19%; amino acid sequences, 12%. Since XJ-160 strain is extremely similar to KYZV, the first could be considered as the KYZV strain. The geography of the KYZV and XJ-160 isolation points and their genetic distance from the European viruses allow the KYZV to be suggested as a SINV (genotype IV) topotypic variant typical of Transcaucasia and Central Asia.
authors.forename: S V
authors.initials: SV
authors.lastname: Al'khovskiĭ
authors.forename: D K
authors.initials: DK
authors.lastname: L'vov
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Shchelkanov
authors.forename: A M
authors.initials: AM
authors.lastname: Shchetinin
authors.forename: P G
authors.initials: PG
authors.lastname: Deriabin
authors.forename: A K
authors.initials: AK
authors.lastname: Gitel'man
authors.forename: A G
authors.initials: AG
authors.lastname: Botikov
authors.forename: E I
authors.initials: EI
authors.lastname: Samokhvalov
mesh_terms: D018354:Alphavirus Infections / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary* / Q000821:virology; D000595:Amino Acid Sequence; D000818:Animals; D001382:Azerbaijan / Q000453:epidemiology; D001483:Base Sequence; D001717:Birds / Q000821:virology*; D003465:Culex / Q000821:virology*; D004199:Disease Vectors; D016679:Genome, Viral; D059014:High-Throughput Nucleotide Sequencing; D008969:Molecular Sequence Data; D010802:Phylogeny; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D012845:Sindbis Virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D014764:Viral Proteins / Q000235:genetics*
chemical_list: D014764:Viral Proteins