title: Early vascular complications after percutaneous cannulation for extracorporeal membrane oxygenation for cardiac assist.
abstract: BACKGROUND
  Extracorporeal membrane oxygenation (VA ECMO) demonstrated an advantage in survival and neurological outcome in patients with cardiogenic shock and, in selected population, in victims of refractory cardiac arrest. The incidence of vascular complications ranges in recent series from 10 to 70% including both early and late complications. The aim of the present study was to determine the incidence of early vascular complications and the effectiveness of the prevention of limb ischemia by the insertion of a catheter for distal perfusion.
  
  
  METHODS
  Data from our registry of 100 patients treated with VA ECMO implanted via percutaneous femoral approach for cardiogenic shock or refractory cardiac arrest were analyzed. If the leg perfusion was inadequate, an additional 7-9 Fr percutaneous catheter distal to the ECMO arterial cannula was placed into the femoral artery to prevent limb ischemia.
  
  
  RESULTS
  Thirty-five patients had early vascular complications. Thirty patients with early ischemia were cannulated with a small reperfusion cannula to obtain antegrade perfusion of the limb. Twenty-six had an effective reperfusion. Seven patients developed a compartment syndrome of the leg requiring urgent fasciotomy that led to clinical improvement and recovery in five, while the other two patients progressed to irreversible ischemia requiring amputation of the limb.
  
  
  CONCLUSIONS
  The majority of ischemic episodes were resolved with the insertion of a distal perfusion catheter. We did not observe any mortal vascular complication, nor any of the observed complications was related to increased mortality.
authors.affiliation: Department of Emergency and Urgency, San Gerardo Hospital, Monza, Italy - l.avalli@hsgerardo.org.
authors.forename: Leonello
authors.initials: L
authors.lastname: Avalli
authors.forename: Fabio
authors.initials: F
authors.lastname: Sangalli
authors.forename: Maurizio
authors.initials: M
authors.lastname: Migliari
authors.forename: Elena
authors.initials: E
authors.lastname: Maggioni
authors.forename: Simona
authors.initials: S
authors.lastname: Gallieri
authors.forename: Vittorio
authors.initials: V
authors.lastname: Segramora
authors.forename: Valter
authors.initials: V
authors.lastname: Camesasca
authors.forename: Francesco
authors.initials: F
authors.lastname: Formica
authors.forename: Giovanni
authors.initials: G
authors.lastname: Paolini
authors.forename: Antonio
authors.initials: A
authors.lastname: Pesenti
mesh_terms: D000368:Aged; D002404:Catheterization / Q000009:adverse effects*; D015199:Extracorporeal Membrane Oxygenation / Q000009:adverse effects*; D005260:Female; D005263:Femoral Artery; D006323:Heart Arrest / Q000628:therapy; D006801:Humans; D007511:Ischemia / Q000517:prevention & control; D035002:Lower Extremity / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012770:Shock, Cardiogenic / Q000628:therapy; D016896:Treatment Outcome; D014652:Vascular Diseases / Q000209:etiology*