title: Aggregation-induced fabrication of fluorescent organic nanorings: selective biosensing of cysteine and application to molecular logic gate.
abstract: Self-aggregation behavior in aqueous medium of four naphthalimide derivatives has exhibited substitution-dependent, unusual, aggregation induced emission enhancement (AIEE) phenomena. Absorption, emission, and time-resolved study initially indicated the formation of J-type fluorescent organic nanoaggregates (FONs). Simultaneous applications of infrared spectroscopy, theoretical studies, and dynamic light scattering (DLS) measurements explored the underlying mechanism of such substitution-selective aggregation of a chloro-naphthalimide organic molecule. Furthermore, transmission electron microscopy (TEM) visually confirmed the formation of ring like FONs with average size of 7.5-9.5 nm. Additionally, naphthalimide FONs also exhibited selective and specific cysteine amino acid sensing property. The specific behavior of NPCl aggregation toward amino acids was also employed as a molecular logic gate in information technology (IT).
authors.affiliation: Department of Chemistry, Jadavpur University, Kolkata-700032, India.
authors.forename: Soumya Sundar
authors.initials: SS
authors.lastname: Mati
authors.affiliation: Department of Chemistry, Jadavpur University, Kolkata-700032, India.
authors.forename: Sayantani
authors.initials: S
authors.lastname: Chall
authors.affiliation: Department of Chemistry, Jadavpur University, Kolkata-700032, India.
authors.forename: Subhash Chandra
authors.initials: SC
authors.lastname: Bhattacharya
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D003545:Cysteine / Q000737:chemistry*; D000067493:Dynamic Light Scattering; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D053644:Naphthalimides / Q000737:chemistry
chemical_list: D053644:Naphthalimides; D003545:Cysteine