title: Aspiration pneumonia and bronchopneumonia in progressive supranuclear palsy treated with qing fei tang: two case reports.
abstract: BACKGROUND
  Qing fei tang, which is used for various respiratory diseases, is useful for reducing relapse of aspiration pneumonia and bronchopneumonia in stroke, but the effect remains unknown in Parkinson's syndrome. We report two cases of Japanese patients with progressive supranuclear palsy and relapsing aspiration pneumonia and bronchopneumonia, which was successfully prevented by qing fei tang.
  
  
  METHODS
  Two Japanese men with progressive supranuclear palsy and receiving total enteral feeding (patient one (66-years-old) and patient two (76-years-old)) had experienced recurrent aspiration pneumonia and bronchopneumonia, which was unresponsive to conventional therapy. The respiratory infection developed twice at intervals of two months in patient one, and nine times at almost monthly intervals in patient two. Thereafter, they were given qing fei tang. After administration of qing fei tang, the respiratory infection reoccurred only once; after 5.5 months for patient one, and six months for patient two. Both of our patients clearly showed a reduced incidence of respiratory infection.
  
  
  CONCLUSIONS
  Both of our patients clearly showed a reduced incidence of respiratory infection after the administration of qing fei tang. Qing fei tang could be useful for the prevention of recurrent aspiration pneumonia and bronchopneumonia in progressive supranuclear palsy.
authors.affiliation: Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 13-1, Takara-machi, Kanazawa, 920-8640, Japan. ichi51@med.kanazawa-u.ac.jp.|Department of Neurology, National Hospital Organization Iou Hospital, Ni-73-1, Iwade-machi, Kanazawa, 920-0192, Japan. ichi51@med.kanazawa-u.ac.jp.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Nozaki
authors.affiliation: Department of Neurology, National Hospital Organization Iou Hospital, Ni-73-1, Iwade-machi, Kanazawa, 920-0192, Japan. ymotozaki@ioudom.hosp.go.jp.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Kato-Motozaki
authors.affiliation: Department of Neurology, National Hospital Organization Iou Hospital, Ni-73-1, Iwade-machi, Kanazawa, 920-0192, Japan. tokuhei@ioudom.hosp.go.jp.
authors.forename: Tokuhei
authors.initials: T
authors.lastname: Ikeda
authors.affiliation: Department of Neurology, National Hospital Organization Iou Hospital, Ni-73-1, Iwade-machi, Kanazawa, 920-0192, Japan. ktakaha@ioudom.hosp.go.jp.
authors.forename: Kazuya
authors.initials: K
authors.lastname: Takahashi
authors.affiliation: Department of Internal Medicine, National Hospital Organization Iou Hospital, Ni-73-1, Iwade-machi, Kanazawa, 920-0192, Japan. azro.tagami@gmail.com.
authors.forename: Atsuro
authors.initials: A
authors.lastname: Tagami
authors.affiliation: Department of Neurology, National Hospital Organization Iou Hospital, Ni-73-1, Iwade-machi, Kanazawa, 920-0192, Japan. cishida@ioudom.hosp.go.jp.
authors.forename: Chiho
authors.initials: C
authors.lastname: Ishida
authors.affiliation: Department of Neurology, National Hospital Organization Iou Hospital, Ni-73-1, Iwade-machi, Kanazawa, 920-0192, Japan. komai@ioudom.hosp.go.jp.
authors.forename: Kiyonobu
authors.initials: K
authors.lastname: Komai
mesh_terms: D000368:Aged; D001996:Bronchopneumonia / Q000188:drug therapy* / Q000209:etiology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011015:Pneumonia, Aspiration / Q000188:drug therapy* / Q000209:etiology; D013494:Supranuclear Palsy, Progressive / Q000150:complications*
chemical_list: D004365:Drugs, Chinese Herbal; C059183:qing-fei-tang