title: [Results of using Solanum tuberosum sprouts extract for the treatment of ophthalmoherpes].
abstract: The efficacy, tolerability and safety of the extract of Solanum tuberosum sprouts (Panavir eyedrops) have been studied on the model of ophthalmic disorder in rabbits caused by herpes simplex virus (HSV) type 1. It is established that Panavir applied via 6 instillations per day for a period of days has potent therapeutic efficacy and prevents the development of gross corneal opacity in rabbits. Instillation of Panavir eyedrops does not cause irritation, toxic and allergic effects and are well tolerated by rabbits. The fastest and most pronounced effect of Panavir eyedrops was observed in the treatment of epithelial keratitis, as well as for not prolonged persistence of HSV. The effectiveness of Panavir eyedrops is comparable with that of the reference preparation OphthalmoferonR.
authors.forename: L M
authors.initials: LM
authors.lastname: Alimbarova
authors.forename: A A
authors.initials: AA
authors.lastname: Lazarenko
authors.forename: A V
authors.initials: AV
authors.lastname: Kiselev
authors.forename: T B
authors.initials: TB
authors.lastname: Tanirbergenov
authors.forename: E V
authors.initials: EV
authors.lastname: Stovbun
mesh_terms: D000818:Animals; D003228:Conjunctiva / Q000187:drug effects / Q000473:pathology / Q000821:virology; D003315:Cornea / Q000187:drug effects / Q000473:pathology / Q000821:virology; D006027:Glycosides / Q000494:pharmacology*; D006561:Herpes Simplex / Q000188:drug therapy* / Q000473:pathology / Q000821:virology; D018259:Herpesvirus 1, Human / Q000187:drug effects / Q000472:pathogenicity / Q000502:physiology; D007634:Keratitis / Q000188:drug therapy* / Q000473:pathology / Q000821:virology; D008297:Male; D009883:Ophthalmic Solutions; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry; D018520:Plant Shoots / Q000737:chemistry*; D011817:Rabbits; D011198:Solanum tuberosum / Q000737:chemistry*
chemical_list: D006027:Glycosides; D009883:Ophthalmic Solutions; C520796:Panavir (Solanum tuberosum); D010936:Plant Extracts