title: Separation of liquid domains in model membranes induced with high hydrostatic pressure.
abstract: We have imaged the formation of membrane microdomains immediately after their induction using a novel technology platform coupling high hydrostatic pressure to fluorescence microscopy. After formation, the ordered domains are small and highly dynamic. This will enhance links between model lipid assemblies and dynamic processes in cellular membranes.
authors.affiliation: Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, UK. nicholas.brooks@imperial.ac.uk.
authors.forename: Nicola L C
authors.initials: NL
authors.lastname: McCarthy
authors.forename: Oscar
authors.initials: O
authors.lastname: Ces
authors.forename: Robert V
authors.initials: RV
authors.lastname: Law
authors.forename: John M
authors.initials: JM
authors.lastname: Seddon
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Brooks
mesh_terms: D002462:Cell Membrane / Q000737:chemistry*; D006874:Hydrostatic Pressure; D008055:Lipids / Q000737:chemistry / Q000302:isolation & purification*; D008856:Microscopy, Fluorescence; D008954:Models, Biological; D053835:Unilamellar Liposomes / Q000737:chemistry
chemical_list: D008055:Lipids; D053835:Unilamellar Liposomes