title: Determination by GC-IT/MS of phytosterols in herbal medicinal products for the treatment of lower urinary tract symptoms and food products marketed in Europe.
abstract: A method for the determination of phytosterols in herbal medicinal products for the treatment of lower urinary tract symptoms and food products is described here. Using a convenient sample preparation protocol and sensitive gas chromatography ion trap mass spectrometry analysis, ten different sterols, among them five Δ(7)-phytosterols as typical constituents of pumpkin seed preparations, could be identified and quantified. This protocol was applied to the analysis of 31 marketed products, from which seven were raw materials.
authors.affiliation: Department für Pharmazie, Zentrum für Pharmaforschung, Ludwig-Maximilians-Universität, München, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Müller
authors.affiliation: Department für Pharmazie, Zentrum für Pharmaforschung, Ludwig-Maximilians-Universität, München, Germany.
authors.forename: Franz
authors.initials: F
authors.lastname: Bracher
mesh_terms: D028464:Cucurbita / Q000737:chemistry*; D005060:Europe; D005504:Food Analysis; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000188:drug therapy; D010840:Phytosterols / Q000032:analysis* / Q000627:therapeutic use; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry* / Q000627:therapeutic use; D015203:Reproducibility of Results; D012639:Seeds / Q000737:chemistry*; D014570:Urologic Diseases / Q000150:complications
chemical_list: D010840:Phytosterols; D010936:Plant Extracts