title: Anaesthesia and orphan disease: marked attenuation of motor evoked potentials by high-dose dexmedetomidine in a child with Angelman syndrome undergoing scoliosis surgery: A case report with pharmacokinetic analysis.
authors.affiliation: From the Division of Anaesthesiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ishii
authors.forename: Andrey B
authors.initials: AB
authors.lastname: Petrenko
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Tobita
authors.forename: Kenta
authors.initials: K
authors.lastname: Furutani
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Baba
mesh_terms: D000293:Adolescent; D000758:Anesthesia / Q000379:methods*; D017204:Angelman Syndrome / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D020927:Dexmedetomidine / Q000008:administration & dosage*; D019054:Evoked Potentials, Motor / Q000187:drug effects* / Q000502:physiology; D005260:Female; D006801:Humans; D016343:Monitoring, Intraoperative / Q000379:methods; D035583:Rare Diseases / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D012600:Scoliosis / Q000150:complications / Q000175:diagnosis / Q000601:surgery*
chemical_list: D020927:Dexmedetomidine