title: Polymer-surfactant complexes for microencapsulation of vitamin E and its release.
abstract: Microencapsulation of vitamin E directly from oil-in-water (o/w) emulsions was carried out by means of a novel practically relevant approach. For the first time, a preformed polyelectrolyte-surfactant complex (sodium polystyrene sulfonate/dodecyl trimethyl ammonium bromide) was simultaneously used as an electrosteric emulsion stabilizer and as a charged precursor for the following build up of microcapsules. Subsequently, a layer-by-layer technique was applied to emulsions leading to the formation of core-shell microcapsules with oily cores and polyelectrolyte shells. The effect of the complexes on the process of emulsion formation and on the stability and characteristics of the resulting emulsions was investigated by measurements of dynamic and equilibrium interfacial tension, size distribution (DLS) and interfacial charge (zeta-potential). The resulting microcapsules were characterized by confocal laser scanning microscopy (CLSM), Cryo-SEM, size distribution and zeta-potential measurements on each stage of the shell assembly. The release kinetics of vitamin E was monitored during the consecutive steps of the encapsulation procedure using UV-vis spectroscopy and showed the progressive enhancement of sustainability. The developed approach may be promising for the practical use in the cosmetic and food industry.
authors.affiliation: International Postgraduate Institute "Excellence PolyTech" of Kazakh National Technical University, Almaty, Kazakhstan; Max-Planck Institute of Colloids and Interfaces, Potsdam, Germany. Electronic address: Altynay.sharipova@mpikg.mpg.de.
authors.forename: A A
authors.initials: AA
authors.lastname: Sharipova
authors.affiliation: International Postgraduate Institute "Excellence PolyTech" of Kazakh National Technical University, Almaty, Kazakhstan.
authors.forename: S B
authors.initials: SB
authors.lastname: Aidarova
authors.affiliation: Max-Planck Institute of Colloids and Interfaces, Potsdam, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Grigoriev
authors.affiliation: Auezov South Kazakhstan State University, Shymkent, Kazakhstan.
authors.forename: B
authors.initials: B
authors.lastname: Mutalieva
authors.affiliation: South Kazakhstan State Pedagogical Institute, Shymkent, Kazakhstan.
authors.forename: G
authors.initials: G
authors.lastname: Madibekova
authors.affiliation: International Postgraduate Institute "Excellence PolyTech" of Kazakh National Technical University, Almaty, Kazakhstan.
authors.forename: A
authors.initials: A
authors.lastname: Tleuova
authors.affiliation: Max-Planck Institute of Colloids and Interfaces, Potsdam, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Miller
mesh_terms: D004339:Drug Compounding; D018613:Microscopy, Confocal; D008855:Microscopy, Electron, Scanning; D011108:Polymers / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry*; D014810:Vitamin E / Q000008:administration & dosage* / Q000737:chemistry
chemical_list: D011108:Polymers; D013501:Surface-Active Agents; D014810:Vitamin E
keywords: Drop profile analysis tensiometry; Microencapsulation; Polymer/surfactant complex; Release profile; Vitamin E; W/o emulsions