title: Malignant glomus tumor with oncocytic features: an unusual presentation of dysphagia.
abstract: Glomus tumors in the gastrointestinal tract are unusual, as the previous series in the literature have been mainly limited to the stomach. Less than 10 cases of esophageal glomus tumors have been described in the literature. Oncocytic glomus tumors are a recently identified, rare variant of the glomus tumor. We report a 47-year-old female who presented with an approximately 3-month history of dysphagia and weight loss. Upper gastrointestinal endoscopy showed a black-purple, hypervascular, protruding lesion measuring approximately 65 mm at the 37th cm of the esophagus. The patient underwent an Ivor Lewis operation via open thoracotomy. The resected specimen had a protuberant, ulcerated mass measuring 80 × 35 mm in the posterior wall of the esophagus. Based on the histopathological, immunohistochemical and electron microscope findings, the final diagnosis was a malignant glomus tumor with oncocytic features. To our knowledge, this is the first report of a malignant glomus tumor with oncocytic features in an esophageal location.
authors.affiliation: Department of Surgical Pathology, Medical Faculty, Uludag University, Bursa, Turkey.
authors.forename: Nesrin
authors.initials: N
authors.lastname: Ugras
authors.affiliation: Department of Surgical Pathology, Medical Faculty, Uludag University, Bursa, Turkey.
authors.forename: Ömer
authors.initials: Ö
authors.lastname: Yercİ
authors.affiliation: Department of Surgical Pathology, Medical Faculty, Uludag University, Bursa, Turkey.
authors.forename: Ulviye
authors.initials: U
authors.lastname: Yalçınkaya
authors.affiliation: Department of General Surgery, Medical Faculty, Uludag University, Bursa, Turkey.
authors.forename: Barış
authors.initials: B
authors.lastname: Gülcü
authors.affiliation: Department of General Surgery, Medical Faculty, Uludag University, Bursa, Turkey.
authors.forename: Ersin
authors.initials: E
authors.lastname: Öztürk
authors.affiliation: Department of Gastroenterology, Medical Faculty, Uludag University, Bursa, Turkey.
authors.forename: Çınar
authors.initials: Ç
authors.lastname: Yıldırım
authors.affiliation: Department of Histology and Embryology, Medical Faculty, Uludag University, Bursa, Turkey.
authors.forename: İlkin
authors.initials: İ
authors.lastname: Çavuşoğlu
mesh_terms: D003680:Deglutition Disorders / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D041981:Gastrointestinal Tract / Q000473:pathology; D005918:Glomus Tumor / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D013908:Thoracotomy; D015431:Weight Loss
keywords: Glomus tumor; esophagus; oncocytic