title: Fast, sensitive, and selective ion-triggered disassembly and release based on tris(bipyridine)ruthenium(II)-functionalized metal-organic frameworks.
abstract: Metal-organic frameworks (MOFs) are microporous materials assembled from metal ions and organic linkers. Recently, many studies have been focused on the syntheses of MOFs with permanent porosity for various applications. However, no attention has been paid to controllable disassembly of MOFs and related applications. In this work, for the first time we synthesized novel tris(bipyridine)ruthenium(II)-functionalized MOFs (i.e., RuMOFs) that could be ion-responsively disassembled and release massive guest materials loaded in the frameworks. The synthesized RuMOFs exhibited much stability in aqueous solutions containing H(+), and many metal ions, but could be selectively and sensitively disassembled by Hg(2+) ions, resulting in the release of large quantities of Ru(bpy)3(2+). The target-responsive release mechanism was investigated and discussed in detail. On the basis of the ion-responsive disassembly and release, an ultrasensitive electrochemiluminescence sensing method for Hg(2+) has been developed with a very low limit of detection (5.3 × 10(-13) M). It was envisioned that the RuMOFs and similar target-responsive functional MOF materials would have promising applications in ultrasensitive and highly selective chemical sensing and even in accurately controllable drug delivering and releasing.
authors.affiliation: †MOE Key Laboratory of Analysis and Detection Technology for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, and College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.
authors.forename: Xiaomei
authors.initials: X
authors.lastname: Lin
authors.affiliation: †MOE Key Laboratory of Analysis and Detection Technology for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, and College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.
authors.forename: Fenqiang
authors.initials: F
authors.lastname: Luo
authors.affiliation: ‡Key Laboratory of Medicinal Chemistry for Natural Resource (Yunnan University), Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kun-ming, Yunnan 650091, China.
authors.forename: Liyan
authors.initials: L
authors.lastname: Zheng
authors.affiliation: †MOE Key Laboratory of Analysis and Detection Technology for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, and College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.
authors.forename: Gongmin
authors.initials: G
authors.lastname: Gao
authors.affiliation: †MOE Key Laboratory of Analysis and Detection Technology for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, and College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China.
authors.forename: Yuwu
authors.initials: Y
authors.lastname: Chi
mesh_terms: D007477:Ions / Q000032:analysis; D008628:Mercury / Q000032:analysis* / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D013997:Time Factors
chemical_list: D007477:Ions; D009942:Organometallic Compounds; C415768:tris(2,2'-bipyridyl)ruthenium(II); D008628:Mercury