title: Influenza Vaccination as a Novel Trigger of Wells Syndrome in a Child.
abstract: Wells syndrome is a rare disorder of unknown etiology. Precipitants include insect bites, infections, medications, malignancies, and vaccinations. Possible mechanisms include hypersensitivity reactions to antigens. There are four reports in the literature of Wells syndrome precipitated by vaccinations (hepatitis B vaccine, tetanus vaccine, tetanus-diptheria vaccine and triple antigen vaccine). We present a further case of Wells syndrome in a 22-month-old child after influenza vaccine as a novel trigger not previously reported.
authors.affiliation: Department of Dermatology, Chelsea and Westminster Hospital, London, UK.
authors.forename: Jacqueline K
authors.initials: JK
authors.lastname: Simpson
authors.affiliation: Department of Dermatology, Chelsea and Westminster Hospital, London, UK.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Patalay
authors.affiliation: Department of Histopathology, Charing Cross Hospital, London, UK.
authors.forename: Nicholas
authors.initials: N
authors.lastname: Francis
authors.affiliation: Department of Dermatology, Chelsea and Westminster Hospital, London, UK.
authors.forename: Nerys
authors.initials: N
authors.lastname: Roberts
mesh_terms: D000956:Antigens, Viral / Q000009:adverse effects; D002481:Cellulitis / Q000209:etiology*; D004802:Eosinophilia / Q000209:etiology*; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology; D007223:Infant; D007252:Influenza Vaccines / Q000009:adverse effects*; D008297:Male; D009975:Orthomyxoviridae / Q000276:immunology; D014611:Vaccination
chemical_list: D000956:Antigens, Viral; D007252:Influenza Vaccines