title: A new polyoxygenated farnesylcyclohexenone from Fungus Penicillium sp.
abstract: A new polyoxygenated farnesylcyclohexenone, peniginsengin A (1), was isolated from the fermentation of Penicillium sp. YIM PH30003, an endophytic fungus associated with Panax notoginseng (Burk.) F. H. Chen. The structure was assigned based on a combination of 1 D and 2 D NMR and mass spectral data. The cytotoxicity and antimicrobial activities of compound 1 were investigated.
authors.affiliation: a School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Yabin
authors.initials: Y
authors.lastname: Yang
authors.affiliation: a School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Fangfang
authors.initials: F
authors.lastname: Yang
authors.affiliation: b Yunnan Institute of Microbiology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Lixing
authors.initials: L
authors.lastname: Zhao
authors.affiliation: a School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Rongting
authors.initials: R
authors.lastname: Duang
authors.affiliation: a School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Guangyi
authors.initials: G
authors.lastname: Chen
authors.affiliation: a School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Xiaozhan
authors.initials: X
authors.lastname: Li
authors.affiliation: a School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Qiling
authors.initials: Q
authors.lastname: Li
authors.affiliation: a School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Shaohuan
authors.initials: S
authors.lastname: Qin
authors.affiliation: a School of Chemical Science and Technology, Yunnan University , Kunming 650091 , P.R. China.
authors.forename: Zhongtao
authors.initials: Z
authors.lastname: Ding
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000737:chemistry* / Q000633:toxicity; D045744:Cell Line, Tumor; D003512:Cyclohexanones / Q000737:chemistry* / Q000633:toxicity; D004354:Drug Screening Assays, Antitumor; D005285:Fermentation; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D053723:Panax notoginseng / Q000382:microbiology; D010407:Penicillium / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D003512:Cyclohexanones; C000609224:peniginsengin A
keywords: Penicillium sp.; peniginsengin A; polyoxygenated farnesylcyclohexenone