title: Can infectious endocarditis during pregnancy be cured with only drug treatment?
abstract: During pregnancy, infective endocarditis (IE) is quite rare but has a high mortality rate in terms of the mother and the fetus. In this article, a 24-year-old patient with a history of mitral valve prolapse (MVP) who was hospitalized due to IE and treated successfully is presented. On echocardiography, severe mitral valve prolapse, severe mitral regurgitation, and vegetation on the posterior leaflet of mitral valve were observed. Streptococcus mitis was subsequently isolated from four sets of blood cultures. The patient was diagnosed with IE. After 6 weeks of antibiotic therapy, the patient was cured completely without surgical treatment. At 40-weeks of pregnancy, the patient gave birth via a normal vaginal delivery. There were no problems with the 3,800-gram baby born. In current guidelines, there is very limited advice on treatment options for patients who develop IE during pregnancy. Therefore, evaluation of patient-based treatment options would be appropriate. In addition, IE prophylaxis for MVP is not recommended in current guidelines. However, in MVP patients with mitral regurgitation, prior to procedures associated with a high risk of infective endocarditis, IE prophylaxis may be rational.
authors.affiliation: Department of Cardiology, Uludag University Faculty of Medicine Hospital, Bursa, Turkey. Email:feyzullabesli@gmail.com.
authors.forename: Serhat
authors.initials: S
authors.lastname: Caliskan
authors.affiliation: Department of Cardiology, Düzce Atatürk State Hospital, Düzce, Turkey.
authors.forename: Feyzullah
authors.initials: F
authors.lastname: Besli
authors.affiliation: Department of Cardiology, Uludag University Faculty of Medicine Hospital, Bursa, Turkey. Email:feyzullabesli@gmail.com.
authors.forename: Saim
authors.initials: S
authors.lastname: Sag
authors.affiliation: Department of Cardiology, Uludag University Faculty of Medicine Hospital, Bursa, Turkey. Email:feyzullabesli@gmail.com.
authors.forename: Fatih
authors.initials: F
authors.lastname: Gungoren
authors.affiliation: Department of Cardiology, Uludag University Faculty of Medicine Hospital, Bursa, Turkey. Email:feyzullabesli@gmail.com.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Baran
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D010400:Penicillin G / Q000008:administration & dosage*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000382:microbiology; D013290:Streptococcal Infections / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D010400:Penicillin G