title: Anesthetic Considerations and Management of Transposition of the Great Arteries.
abstract: Transposition of the great arteries was once an almost uniformly fatal disease in infancy. Six decades of advances in surgical techniques, intraoperative care, and perioperative management have led to at least 90% of patients reaching adulthood, most with a good quality of life. This review summarizes medical and surgical decision making during the neonatal perioperative period, with a special emphasis on factors pertinent to the anesthetic evaluation and care during primary surgical repair of transposition of the great arteries. A review is also provided of anesthetic considerations for noncardiac surgery later in childhood or adulthood, for those survivors of the arterial switch operation, Rastelli procedure, Nikaidoh procedure, and the réparation á l'étage ventriculaire procedure.
authors.affiliation: University of Washington School of Medicine, Seattle, WA, USA Seattle Children's Hospital, Seattle, WA, USA gregory.latham@seattlechildrens.org.
authors.forename: Gregory J
authors.initials: GJ
authors.lastname: Latham
authors.affiliation: University of Washington School of Medicine, Seattle, WA, USA Seattle Children's Hospital, Seattle, WA, USA.
authors.forename: Denise C
authors.initials: DC
authors.lastname: Joffe
authors.affiliation: University of Washington School of Medicine, Seattle, WA, USA Seattle Children's Hospital, Seattle, WA, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Eisses
authors.affiliation: University of Washington School of Medicine, Seattle, WA, USA Seattle Children's Hospital, Seattle, WA, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Richards
authors.affiliation: University of Washington School of Medicine, Seattle, WA, USA Seattle Children's Hospital, Seattle, WA, USA.
authors.forename: Jeremy M
authors.initials: JM
authors.lastname: Geiduschek
mesh_terms: D000328:Adult; D000758:Anesthesia / Q000379:methods*; D000777:Anesthetics / Q000008:administration & dosage*; D002648:Child; D006801:Humans; D007231:Infant, Newborn; D019990:Perioperative Care / Q000379:methods; D011788:Quality of Life; D017741:Survivors; D014188:Transposition of Great Vessels / Q000503:physiopathology / Q000601:surgery*
chemical_list: D000777:Anesthetics
keywords: cardiac anesthesia; children; congenital heart disease; deep hypothermic circulatory arrest; neonatal intensive care; neonate