title: Unilateral adnexal agenesis and dermoid cyst: fertility implications.
abstract: We report the loss of potential fertility in a 23-year-old nulliparous woman who attended the outpatient gynaecological endocrinology clinic for amenorrhea and hot flushes started after a laparoscopic surgery for dermoid cyst. During surgery an unilateral ovarian and fallopian tube agenesis were found. The hormonal evaluation was performed. The results evidenced high plasma levels of LH and FSH. Their values were 56.6 and 121.3 mUI/ml, respectively. The concentrations of plasma E2 were < 20 pg/ml and of AMH were <0.08 ng/ml. Genetic analysis showed normal karyotype (46, XX). We think that if an embryological defect is suspected, an appropriate counselling about fertility preservation along with the assessment of hormonal levels before ovarian surgery should be recommended to all women in the reproductive age in order to offer future reproductive chances.
authors.affiliation: Department of Clinical and Experimental Medicine, Division of Gynecology and Obstetrics, University of Pisa , Pisa , Italy.
authors.forename: Franca
authors.initials: F
authors.lastname: Fruzzetti
authors.forename: Fiorella
authors.initials: F
authors.lastname: Bucci
authors.forename: Daria
authors.initials: D
authors.lastname: Perini
authors.forename: Angiolo
authors.initials: A
authors.lastname: Gadducci
mesh_terms: D000328:Adult; D005187:Fallopian Tubes / Q000002:abnormalities* / Q000000981:diagnostic imaging; D005260:Female; D059247:Fertility Preservation / Q000592:standards*; D006801:Humans; D010048:Ovarian Cysts / Q000097:blood / Q000000981:diagnostic imaging / Q000601:surgery*; D010053:Ovary / Q000002:abnormalities* / Q000000981:diagnostic imaging; D014463:Ultrasonography; D055815:Young Adult
keywords: Adnexal agenesis; dermoid cyst; fertility preservation; genital ridge defects