title: Current role of dexmedetomidine in clinical anesthesia and intensive care.
abstract: Dexmedetomidine is a new generation highly selective α2-adrenergic receptor (α2-AR) agonist that is associated with sedative and analgesic sparing effects, reduced delirium and agitation, perioperative sympatholysis, cardiovascular stabilizing effects, and preservation of respiratory function. The aim of this review is to present the most recent topics regarding the advantages in using dexmedetomidine in clinical anesthesia and intensive care, while discussing the controversial issues of its harmful effects.
authors.affiliation: Department of Anaesthesia and Critical Care, All India Institute of Medical Sciences, J.P.N.A Trauma Centre, New Delhi, India.
authors.forename: Manpreet
authors.initials: M
authors.lastname: Kaur
authors.affiliation: Department of Anaesthesia and Critical Care, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: P M
authors.initials: PM
authors.lastname: Singh
keywords: Dexmedetomidine; intensive care unit sedation; α2-adrenergic receptor agonist