title: Mucosal pigmentation of the hard palate in a patient taking imatinib.
abstract: Imatinib mesylate is used in the treatment of chronic myeloid leukaemia, among other conditions. Oral mucosal pigmentation as a side effect is rare. We present a summary of the current literature and a case report of a 58-year-old Caucasian woman who presented with a diffuse blue-grey pigmentation of the palatal mucosa, thought to be related to long-term use of imatinib mesylate.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Ashford and St Peter's Hospitals, Surrey, UK.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Lyne
authors.affiliation: Department of Oral and Maxillofacial Surgery, Ashford and St Peter's Hospitals, Surrey, UK.
authors.forename: Alex
authors.initials: A
authors.lastname: Creedon
authors.affiliation: Department of Oral and Maxillofacial Surgery, Ashford and St Peter's Hospitals, Surrey, UK.
authors.forename: Basil Malcolm West
authors.initials: BM
authors.lastname: Bailey
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced*; D000068877:Imatinib Mesylate / Q000009:adverse effects* / Q000627:therapeutic use; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy; D008875:Middle Aged; D009059:Mouth Diseases / Q000139:chemically induced* / Q000473:pathology; D009061:Mouth Mucosa / Q000187:drug effects* / Q000473:pathology; D021362:Palate, Hard
chemical_list: D000970:Antineoplastic Agents; D000068877:Imatinib Mesylate