title: Buccal versus vaginal misoprostol administration for the induction of first and second trimester abortions.
abstract: OBJECTIVE
  To compare the effectiveness, side effects, and patient satisfaction of buccal versus vaginal misoprostol administration in first and second trimester induced abortions.
  
  
  METHODS
  In first trimester, women received oral mifepristone followed by misoprostol either by buccal or vaginal route. In second trimester, women received oral mifepristone followed by repeated doses of misoprostol either by buccal or vaginal route. A comparative analysis using SPSS was done.
  
  
  RESULTS
  In first trimester, success rate of medical abortion was 96 % in buccal group and 88 % in vaginal group. Nausea was the most common adverse effect which was similar in both groups. In second trimester, success rate was 96 % in buccal group and 80 % in vaginal group. A statistically higher incidence of nausea was noticed in buccal group. Patient satisfaction level was almost similar in both the groups in both trimesters.
  
  
  CONCLUSIONS
  Buccal and vaginal routes of misoprostol administration have similar efficacy and patient satisfaction level for first and second trimester induced abortions. Hence, buccal route may serve as an alternative to vaginal misoprostol.
authors.affiliation: Department of Obstetrics and Gynecology, Government Multispeciality Hospital Sector 16, Chandigarh, India.
authors.forename: Geetika
authors.initials: G
authors.lastname: Garg
authors.affiliation: Department of Obstetrics and Gynecology, Government Medical College and Hospital, Sector 32, Chandigarh, India.
authors.forename: Navneet
authors.initials: N
authors.lastname: Takkar
authors.affiliation: Department of Obstetrics and Gynecology, Government Medical College and Hospital, Sector 32, Chandigarh, India.
authors.forename: Alka
authors.initials: A
authors.lastname: Sehgal
keywords: Abortions; Buccal; Misoprostol; Vaginal