title: Complication of chronic eosinophilic pneumonia in an elderly patient with Sjögren syndrome.
abstract: An 81-year-old Japanese male with primary Sjögren syndrome (pSS) developed a low-grade fever and productive cough which were refractory to antibiotic therapy. Based on the high level of eosinophils observed in his bronchial alveolar lavage, he was diagnosed with chronic eosinophilic pneumonia (CEP) and successfully treated by oral prednisolone. Interstitial lung diseases associated with pSS (pSS-ILDs) usually present as nonspecific interstitial pneumonia or usual interstitial pneumonia; therefore, the present case is extremely unique in that the patient's condition was complicated with CEP. A diagnosis of advanced gallbladder cancer was made in the patient's clinical course, suggesting the advisability of a whole-body workup in cases of pSS, especially in elderly patients.
authors.affiliation: Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.kazukazun2006@yahoo.co.jp.
authors.forename: Koichi
authors.initials: K
authors.lastname: Waseda
authors.forename: Hideharu
authors.initials: H
authors.lastname: Hagiya
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Hanayama
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Terasaka
authors.forename: Kosuke
authors.initials: K
authors.lastname: Kimura
authors.forename: Takao
authors.initials: T
authors.lastname: Tsuzuki
authors.forename: Kou
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nada
authors.forename: Eri
authors.initials: E
authors.lastname: Nakamura
authors.forename: Kazutoshi
authors.initials: K
authors.lastname: Murakami
authors.forename: Eisei
authors.initials: E
authors.lastname: Kondo
authors.forename: Fumio
authors.initials: F
authors.lastname: Otsuka
mesh_terms: D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000369:Aged, 80 and over; D002908:Chronic Disease; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D011657:Pulmonary Eosinophilia / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D012859:Sjogren's Syndrome / Q000150:complications*; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D011239:Prednisolone