title: Studying brain functions with mesoscopic measurements: Advances in electrocorticography for non-human primates.
abstract: Our brain is organized in a modular structure. Information in different modalities is processed within distinct cortical areas. However, individual cortical areas cannot enable complex cognitive functions without interacting with other cortical areas. Electrocorticography (ECoG) has recently become an important tool for studying global network activity across cortical areas in animal models. With stable recordings of electrical field potentials from multiple cortical areas, ECoG provides an opportunity to systematically study large-scale cortical activity at a mesoscopic spatiotemporal resolution under various experimental conditions. Recent developments in thin, flexible ECoG electrodes permit recording field potentials from not only gyral but intrasulcal cortical surfaces. Our review here focuses on the recent advances of ECoG applications to non-human primates.
authors.affiliation: Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, 49 Convent Drive, Bethesda, MD 20892, USA.
authors.forename: Makoto
authors.initials: M
authors.lastname: Fukushima
authors.affiliation: Laboratory for Adaptive Intelligence Brain Science Institute, RIKEN, 2-1 Hirosawa, Wako 351-0198, Saitama, Japan.
authors.forename: Zenas C
authors.initials: ZC
authors.lastname: Chao
authors.affiliation: Laboratory for Adaptive Intelligence Brain Science Institute, RIKEN, 2-1 Hirosawa, Wako 351-0198, Saitama, Japan. Electronic address: na@brain.riken.jp.
authors.forename: Naotaka
authors.initials: N
authors.lastname: Fujii
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D000069280:Electrocorticography / Q000379:methods*; D009415:Nerve Net / Q000502:physiology*; D011323:Primates