title: Kidney retransplantation for BK virus nephropathy with active viremia without allograft nephrectomy.
abstract: BK virus nephropathy is an important cause of kidney allograft failure. Retransplantation has been successfully performed for patients with previous allograft loss due to BK virus nephropathy; however, whether allograft nephrectomy and viral clearance are required prior to retransplantation is controversial. Some recent studies have suggested that retransplantion can be successfully achieved without allograft nephrectomy if viremia is cleared prior to retransplant. The only published experience of successful retransplantation in the presence of active viremia occurred in the presence of concomitant allograft nephrectomy of the failing kidney. In this report, we describe a case of successful repeat kidney transplant in a patient with high-grade BK viremia and fulminant hepatic failure without concomitant allograft nephrectomy performed under the setting of a simultaneous liver-kidney transplant.
authors.affiliation: UCLA Division of Nephrology, UCLA David Geffen School of Medicine, 1015 Gayley Avenue, Suite #220, Los Angeles, CA, 90024, USA.
authors.forename: Jingbo
authors.initials: J
authors.lastname: Huang
authors.affiliation: UCLA Division of Nephrology, UCLA David Geffen School of Medicine, 1015 Gayley Avenue, Suite #220, Los Angeles, CA, 90024, USA.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Danovitch
authors.affiliation: UCLA Division of Nephrology, UCLA David Geffen School of Medicine, 1015 Gayley Avenue, Suite #220, Los Angeles, CA, 90024, USA.
authors.forename: Phuong-Thu
authors.initials: PT
authors.lastname: Pham
authors.affiliation: UCLA Division of Nephrology, UCLA David Geffen School of Medicine, 1015 Gayley Avenue, Suite #220, Los Angeles, CA, 90024, USA.
authors.forename: Suphamai
authors.initials: S
authors.lastname: Bunnapradist
authors.affiliation: UCLA Division of Nephrology, UCLA David Geffen School of Medicine, 1015 Gayley Avenue, Suite #220, Los Angeles, CA, 90024, USA. edmundhuang@mednet.ucla.edu.
authors.forename: Edmund
authors.initials: E
authors.lastname: Huang
mesh_terms: D000368:Aged; D064591:Allografts; D001739:BK Virus; D005260:Female; D006084:Graft Rejection / Q000821:virology; D006801:Humans; D007674:Kidney Diseases / Q000601:surgery* / Q000821:virology; D016030:Kidney Transplantation; D016031:Liver Transplantation; D009392:Nephrectomy; D027601:Polyomavirus Infections / Q000150:complications*; D012086:Reoperation; D014412:Tumor Virus Infections / Q000150:complications*; D014766:Viremia / Q000821:virology*
keywords: Active BK viremia; Allograft nephrectomy; BK virus nephropathy; Retransplantation