title: Babelomics 5.0: functional interpretation for new generations of genomic data.
abstract: Babelomics has been running for more than one decade offering a user-friendly interface for the functional analysis of gene expression and genomic data. Here we present its fifth release, which includes support for Next Generation Sequencing data including gene expression (RNA-seq), exome or genome resequencing. Babelomics has simplified its interface, being now more intuitive. Improved visualization options, such as a genome viewer as well as an interactive network viewer, have been implemented. New technical enhancements at both, client and server sides, makes the user experience faster and more dynamic. Babelomics offers user-friendly access to a full range of methods that cover: (i) primary data analysis, (ii) a variety of tests for different experimental designs and (iii) different enrichment and network analysis algorithms for the interpretation of the results of such tests in the proper functional context. In addition to the public server, local copies of Babelomics can be downloaded and installed. Babelomics is freely available at: http://www.babelomics.org.
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain Computational Genomics Chair, Bull-CIPF, Valencia, 46012, Spain.
authors.forename: Roberto
authors.initials: R
authors.lastname: Alonso
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain Bioinformatics of Rare Diseases (BIER), CIBER de Enfermedades Raras (CIBERER), Valencia, 46012, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Salavert
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Garcia-Garcia
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain.
authors.forename: Jose
authors.initials: J
authors.lastname: Carbonell-Caballero
authors.affiliation: Department of Medicine, University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK.
authors.forename: Marta
authors.initials: M
authors.lastname: Bleda
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain.
authors.forename: Luz
authors.initials: L
authors.lastname: Garcia-Alonso
authors.affiliation: Fundación Investigación Clínico de Valencia-INCLIVA, Valencia, 46010, Spain.
authors.forename: Alba
authors.initials: A
authors.lastname: Sanchis-Juan
authors.affiliation: Fundación Investigación Clínico de Valencia-INCLIVA, Valencia, 46010, Spain.
authors.forename: Daniel
authors.initials: D
authors.lastname: Perez-Gil
authors.affiliation: Fundación Investigación Clínico de Valencia-INCLIVA, Valencia, 46010, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Marin-Garcia
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain Functional Genomics Node, (INB) at CIPF, Valencia, 46012, Spain.
authors.forename: Ruben
authors.initials: R
authors.lastname: Sanchez
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain.
authors.forename: Cankut
authors.initials: C
authors.lastname: Cubuk
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain.
authors.forename: Marta R
authors.initials: MR
authors.lastname: Hidalgo
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain.
authors.forename: Alicia
authors.initials: A
authors.lastname: Amadoz
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain.
authors.forename: Rosa D
authors.initials: RD
authors.lastname: Hernansaiz-Ballesteros
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain Bioinformatics of Rare Diseases (BIER), CIBER de Enfermedades Raras (CIBERER), Valencia, 46012, Spain.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Alemán
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain.
authors.forename: Joaquin
authors.initials: J
authors.lastname: Tarraga
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain.
authors.forename: David
authors.identifier: http://orcid.org/0000-0002-2484-3278
authors.initials: D
authors.lastname: Montaner
authors.affiliation: HPC Services, University of Cambridge, Cambridge, CB3 0RB UK.
authors.forename: Ignacio
authors.initials: I
authors.lastname: Medina
authors.affiliation: Computational Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46012, Spain Computational Genomics Chair, Bull-CIPF, Valencia, 46012, Spain Bioinformatics of Rare Diseases (BIER), CIBER de Enfermedades Raras (CIBERER), Valencia, 46012, Spain Functional Genomics Node, (INB) at CIPF, Valencia, 46012, Spain jdopazo@cipf.es.
authors.forename: Joaquin
authors.initials: J
authors.lastname: Dopazo
mesh_terms: D020869:Gene Expression Profiling; D023281:Genomics / Q000379:methods*; D059014:High-Throughput Nucleotide Sequencing; D020407:Internet; D009369:Neoplasms / Q000235:genetics; D017423:Sequence Analysis, RNA; D012984:Software