title: Sugammadex: A revolutionary drug in neuromuscular pharmacology.
abstract: Sugammadex (ORG 25969) is a unique neuromuscular reversal drug; a novel cyclodextrin, the first in a new class of selective relaxant binding agents, which reverse neuromuscular blockade (NMB) with the aminosteroid non-depolarizing muscle relaxants rocuronium and vecuronium. Sugammadex can reverse moderate or deep NMB. The clinical use of sugammadex promises to eliminate many of the shortcomings in current anesthetic practice with regard to antagonism of rocuronium and other aminosteroid muscle relaxants.
authors.affiliation: Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College, Pillaiyarkuppam, Puducherry, India.
authors.forename: Kusha
authors.initials: K
authors.lastname: Nag
authors.affiliation: Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College, Pillaiyarkuppam, Puducherry, India.
authors.forename: Dewan Roshan
authors.initials: DR
authors.lastname: Singh
authors.affiliation: Department of Anaesthesiology, Krishna Institute of Medical Sciences, Karad, Maharashtra, India.
authors.forename: Akshaya N
authors.initials: AN
authors.lastname: Shetti
authors.affiliation: Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College, Pillaiyarkuppam, Puducherry, India.
authors.forename: Hemanth
authors.initials: H
authors.lastname: Kumar
authors.affiliation: Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College, Pillaiyarkuppam, Puducherry, India.
authors.forename: T
authors.initials: T
authors.lastname: Sivashanmugam
authors.affiliation: Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College, Pillaiyarkuppam, Puducherry, India.
authors.forename: S
authors.initials: S
authors.lastname: Parthasarathy
keywords: Encapsulation; residual paralysis; rocuronium; selective relaxant binding agent; sugammadex