title: [Reinfection of Schistosoma japonicum and related risk factors in Chinese: Meta-analysis].
abstract: OBJECTIVE
  To study the dynamics of the reinfection of Schistosoma japonicum and related risk factors among the people in schistosomiasis endemic areas in China.
  
  
  METHODS
  Literature retrieval was conducted by using databases of PubMed, CNKI,VIP and Wanfang to collected all the data about the human re-infection of Schistosoma japonicum and related risk factors in the endemic areas in China. And a Mata-analysis was conducted on the literatures met the inclusion standards.
  
  
  RESULTS
  Eighteen studies involving 12 604 people for infection survey and 3 128 people for re-infection survey were included in the analysis. The overall infection rate was 20.8%, and the overall re-infection rate was 21.0% . The difference had no statistical significance (Z = 1.12, P = 0.26). The re-infection related factors included baseline infection intensity (OR = 3.58, 95% CI: 1.56-8.22); the index of contaminated water OR = 2.37, 95% CI: 1.08-5.22); distance from house to river-side (OR = 1.72, 95% CI: 0.41-7.30) and age (OR = 0.48, 95% CI: 0.19-1.23).
  
  
  CONCLUSIONS
  The baseline infection intensity, the index of contaminated water and distance from house to river-side were the risk factors related to the re-infection of Schistosoma japonicum and age was a protective factor.
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health of Wuhan University, Wuhan 430071, China.
authors.forename: Ao
authors.initials: A
authors.lastname: Yang
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health of Wuhan University, Wuhan 430071, China.
authors.forename: Zhenhong
authors.initials: Z
authors.lastname: Nie
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health of Wuhan University, Wuhan 430071, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Chen
authors.affiliation: Institute for Schistosomiasis Prevention, Hubei Provincial Center for Disease Control and Prevention.
authors.forename: Shunxiang
authors.initials: S
authors.lastname: Cai
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health of Wuhan University, Wuhan 430071, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health of Wuhan University, Wuhan 430071, China. Email: guoyi@whu.edu.cn.
authors.forename: Yi
authors.initials: Y
authors.lastname: Guo
mesh_terms: D000818:Animals; D044466:Asian People; D002681:China; D006801:Humans; D012307:Risk Factors; D012549:Schistosoma japonicum; D012554:Schistosomiasis japonica / Q000453:epidemiology* / Q000469:parasitology