title: Apicomplexan cell cycle flexibility: centrosome controls the clutch.
abstract: The centrosome serves as a central hub coordinating multiple cellular events in eukaryotes. A recent study in Toxoplasma gondii revealed a unique bipartite structure of the centrosome, which coordinates the nuclear cycle (S-phase and mitosis) and budding cycle (cytokinesis) of the parasite, and deciphers the principle behind flexible apicomplexan cell division modes.
authors.affiliation: Department of Biology, Boston College, Chestnut Hill, MA 02467, USA.
authors.forename: Chun-Ti
authors.initials: CT
authors.lastname: Chen
authors.affiliation: Department of Biology, Boston College, Chestnut Hill, MA 02467, USA. Electronic address: gubbelsj@bc.edu.
authors.forename: Marc-Jan
authors.initials: MJ
authors.lastname: Gubbels
mesh_terms: D018797:Cell Cycle Proteins / Q000235:genetics*; D048750:Cell Nucleus Division; D018385:Centrosome / Q000378:metabolism*; D048749:Cytokinesis; D006801:Humans; D015800:Protozoan Proteins / Q000235:genetics*; D014122:Toxoplasma / Q000235:genetics*
chemical_list: D018797:Cell Cycle Proteins; D015800:Protozoan Proteins
keywords: Toxoplasma gondii; apicomplexa; centrosome; endodyogeny; schizogony