title: [Current concepts in pathogenesis of age-related macular degeneration].
abstract: Age-related macular degeneration is the leading cause of central blindness in elderly population of the western world. The pathogenesis of this disease, likely multifactorial, is not well known, although a number of theories have been put forward, including oxidative stress, genetic interactions, hemodynamic imbalance, immune and inflammatory processes. The understanding of age-related macular degeneration pathogenesis will give rise to new approaches in prevention and treatment of the early and late stages of both atrophic and neovascular age-related macular degeneration.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Kubicka-Trząska
authors.forename: Izabella
authors.initials: I
authors.lastname: Karska-Basta
authors.forename: Bożena
authors.initials: B
authors.lastname: Romanowska-Dixon
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001766:Blindness / Q000209:etiology / Q000517:prevention & control*; D003941:Diagnostic Techniques, Ophthalmological; D019468:Disease Management; D018450:Disease Progression; D006801:Humans; D008268:Macular Degeneration / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology*; D018384:Oxidative Stress