title: Recurrent sebaceous carcinoma of the eyelid: Outcome after postoperative reirradiation.
abstract: BACKGROUND
  The purpose of this study was for us to describe a case of recurrent sebaceous carcinoma treated with postoperative reirradiation.
  
  
  METHODS
  A 38-year-old man was diagnosed with sebaceous carcinoma of the right lower eyelid. The patient developed local recurrence 4 times, with the first one at 30 months after the excision. The first local recurrence was treated with excision and postoperative radiotherapy with 60 Gy/30 fractions/6 weeks. He manifested preauricular nodal metastasis with the third local recurrence, which was confirmed with (18)F-fluorodeoxyglucose positron emission tomography-CT ((18)F-FDG PET-CT). He received 2 courses of adjuvant reirradiation to the right orbit with 45 Gy/25 fractions/5 weeks and 30 Gy/15 fractions/3 weeks, respectively.
  
  
  RESULTS
  The patient was successfully treated with no evidence of locoregional recurrence at 2 years after the cancer-directed therapy. The patient's follow-up from the date of diagnosis has been 9 years.
  
  
  CONCLUSIONS
  Adjuvant reirradiation with modest doses may be considered with a view to provide disease control and long-term survival.
authors.affiliation: Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Puja
authors.identifier: http://orcid.org/0000-0002-4714-7398
authors.initials: P
authors.lastname: Sahai
authors.affiliation: Department of Surgical Oncology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Nootan Kumar
authors.initials: NK
authors.lastname: Shukla
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Saurabh
authors.initials: S
authors.lastname: Arora
authors.affiliation: Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Bidhu Kalyan
authors.initials: BK
authors.lastname: Mohanti
mesh_terms: D018266:Adenocarcinoma, Sebaceous / Q000556:secondary* / Q000628:therapy*; D000328:Adult; D019882:Blepharoplasty / Q000379:methods; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000628:therapy*; D005153:Facial Neoplasms / Q000556:secondary / Q000628:therapy; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000628:therapy*; D049268:Positron-Emission Tomography / Q000379:methods; D011184:Postoperative Period; D019275:Radiopharmaceuticals / Q000494:pharmacology; D018714:Radiotherapy, Adjuvant / Q000379:methods; D000069475:Re-Irradiation; D012086:Reoperation; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals
keywords: adjuvant radiotherapy; eyelids; recurrence; reirradiation; sebaceous gland neoplasms