title: CSF Concentration of Crizotinib in Two ALK-Positive Non-Small-Cell Lung Cancer Patients with CNS Metastases Deriving Clinical Benefit from Treatment.
authors.affiliation: Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy. Electronic address: giulio.metro@yahoo.com.
authors.forename: Giulio
authors.initials: G
authors.lastname: Metro
authors.affiliation: Medical Oncology, Sacro Cuore-Don Calabria Hospital, Negrar, VR, Italy.
authors.forename: Gianluigi
authors.initials: G
authors.lastname: Lunardi
authors.affiliation: Neuroradiology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.
authors.forename: Piero
authors.initials: P
authors.lastname: Floridi
authors.affiliation: dto-LABS, Agilent Partner Lab, Resana, TV, Italy.
authors.forename: Jennifer P
authors.initials: JP
authors.lastname: Pascali
authors.affiliation: Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Marcomigni
authors.affiliation: Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.
authors.forename: Rita
authors.initials: R
authors.lastname: Chiari
authors.affiliation: Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.
authors.forename: Vienna
authors.initials: V
authors.lastname: Ludovini
authors.affiliation: Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.
authors.forename: Lucio
authors.initials: L
authors.lastname: Crinò
authors.affiliation: Medical Oncology, Sacro Cuore-Don Calabria Hospital, Negrar, VR, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Gori
mesh_terms: D000328:Adult; D000077548:Anaplastic Lymphoma Kinase; D000970:Antineoplastic Agents / Q000134:cerebrospinal fluid* / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000134:cerebrospinal fluid / Q000188:drug therapy* / Q000556:secondary; D002289:Carcinoma, Non-Small-Cell Lung / Q000097:blood / Q000134:cerebrospinal fluid* / Q000556:secondary; D000077547:Crizotinib; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000134:cerebrospinal fluid* / Q000188:drug therapy; D008297:Male; D055756:Meningeal Carcinomatosis / Q000188:drug therapy* / Q000556:secondary; D008875:Middle Aged; D011720:Pyrazoles / Q000097:blood / Q000134:cerebrospinal fluid* / Q000627:therapeutic use; D011725:Pyridines / Q000097:blood / Q000134:cerebrospinal fluid* / Q000627:therapeutic use; D020794:Receptor Protein-Tyrosine Kinases / Q000032:analysis
chemical_list: D000970:Antineoplastic Agents; D011720:Pyrazoles; D011725:Pyridines; D000077547:Crizotinib; C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases