title: Primary leptomeningeal glioblastoma with systemic metastases-case report and review of literature.
abstract: We present a case of a rare meningeal glioblastoma with extensive systemic metastases, along with a review of the existing literature. The patient presented with headache and visual and sensory symptoms and had a rapidly progressive clinical course despite therapy. The patient went on to develop spinal, orbital, muscular, and cutaneous metastases over a short period. Review of the literature reveals 13 similar previously reported cases, none with a similar presentation.
authors.affiliation: Department of Radiology, 200 Hawkins Drive, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA. Electronic address: girish-bathla@uiowa.edu.
authors.forename: Girish
authors.initials: G
authors.lastname: Bathla
authors.affiliation: Department of Pathology, 200 Hawkins Drive, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA.
authors.forename: Sarika
authors.initials: S
authors.lastname: Gupta
authors.affiliation: Department of Radiology, 200 Hawkins Drive, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA.
authors.forename: Toshio
authors.initials: T
authors.lastname: Moritani
mesh_terms: D018450:Disease Progression; D005909:Glioblastoma / Q000556:secondary*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology*; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000556:secondary*; D012878:Skin Neoplasms / Q000556:secondary*; D013125:Spinal Neoplasms / Q000556:secondary*
keywords: Glioblastoma; MRI; Metastases; Orbit; Spine