title: [Experience of Vasonat usage in treatment of patients with chronic toxic hepatitis].
abstract: The authors performed the clinical study of efficiency of Vasonat usage in complex treatment of chronic toxic hepatitis. Under observation there were 122 patients with chronic toxic hepatitis (37--with chronic medicament hepatitis and 85--with chronic alcohol hepatitis). During treatment with Vasonat the severity of clinical signs decreased to 0-1 points, GGTP level decreased in 2,2 times that showed the better efficiency of Vasonat usage compare with basis treatment. Thus Vasonat in dosage 500 mg per day may be recommend to inclusion on complex treatment of patients with chronic toxic hepatitis.
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Stepanov
authors.forename: L M
authors.initials: LM
authors.lastname: Shendrik
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D002317:Cardiovascular Agents / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D058492:Drug Repositioning; D005260:Female; D006521:Hepatitis, Chronic / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008297:Male; D008763:Methylhydrazines / Q000627:therapeutic use*; D008875:Middle Aged; D020011:Protective Agents / Q000627:therapeutic use*; D012720:Severity of Illness Index; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D002317:Cardiovascular Agents; D008763:Methylhydrazines; D020011:Protective Agents; C050147:3-(2,2,2-trimethylhydrazine)propionate; D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D001663:Bilirubin