title: Treatment of severe mucogingival defects with a combination of strip gingival grafts and a xenogeneic collagen matrix: a prospective case series study.
abstract: Large areas of mucogingival alterations may result from advanced regenerative procedures. This prospective case series study was performed to introduce and evaluate a surgical approach that combines the strip gingival graft technique with the use of a xenogeneic collagen matrix. The primary outcome measurement was the increase in keratinized tissue width from baseline to 12 months postprocedure. Twenty patients were enrolled, and they all completed the 12-month evaluation. All treated sites exhibited a significant gain in keratinized tissue at 12 months, with a mean width of 6.33 mm (SD: 2.16), while there was a 43% contraction of the grafted area at 6 months. Tissue dimensions remained stable between 6 and 12 months. The use of the combination graft was well accepted by the patients, with minimal morbidity according to the patients' low self-reported pain and the low utilization of pain medication.
authors.forename: Istvan A
authors.initials: IA
authors.lastname: Urban
authors.forename: Jaime L
authors.initials: JL
authors.lastname: Lozada
authors.forename: Katalin
authors.initials: K
authors.lastname: Nagy
authors.forename: Mariano
authors.initials: M
authors.lastname: Sanz
mesh_terms: D000540:Alveolar Ridge Augmentation / Q000009:adverse effects*; D003094:Collagen / Q000627:therapeutic use*; D005260:Female; D005881:Gingiva / Q000637:transplantation*; D005893:Gingivoplasty / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011446:Prospective Studies; D016896:Treatment Outcome; D014716:Vertical Dimension
chemical_list: D003094:Collagen