title: Nano Clinoptilolite: Highly Efficient Catalyst for the Synthesis of Chromene Derivatives Under Solvent-Free Conditions.
abstract: An efficient and selective synthesis of substituted chromene derivatives via three-component reaction of 4-hydroxycoumarin or 1,3-dicarbonyl compounds, activated acetylenic compounds and N-nucleophiles is described. The reaction was conducted under solvent-free conditions at 70°C using potassium fluoride impregnated on natural zeolite as a cheap and available solid base. The procedure has several advantages involving selectivity, excellent yields and a convenient work-up method.
authors.forename: Sara
authors.initials: S
authors.lastname: Hallajian
authors.affiliation: Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran. m.khalilzadeh@hotmmail.com.
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Khalilzadeh
authors.forename: Mahgol
authors.initials: M
authors.lastname: Tajbakhsh
authors.forename: Eskandar
authors.initials: E
authors.lastname: Alipour
authors.forename: Zahra
authors.initials: Z
authors.lastname: Safaei
mesh_terms: D015110:4-Hydroxycoumarins / Q000737:chemistry; D000114:Acetylene / Q000737:chemistry; D001578:Benzopyrans / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D057166:High-Throughput Screening Assays; D015394:Molecular Structure; D049329:Nanostructures / Q000737:chemistry*; D011804:Quinolines / Q000737:chemistry; D017641:Zeolites / Q000737:chemistry*
chemical_list: D015110:4-Hydroxycoumarins; D001578:Benzopyrans; D011804:Quinolines; C083175:clinoptilolite; D017641:Zeolites; D000114:Acetylene; C068805:4-hydroxycoumarin