title: The assessment of anterior and posterior ocular structures in hyperopic anisometropic amblyopia.
abstract: BACKGROUND
  The aim of this study was to examine the relationship or differences in ocular structures of amblyopic eyes compared to fellow eyes in children and young adults with hyperopic anisometropic amblyopia.
  
  
  METHODS
  Hyperopic participants with anisometropic amblyopia, defined as the presence of best-corrected visual acuity differences of at least 2 Snellen lines and 1.5 diopters between amblyopic and fellow eyes, were studied. Using the IOL Master, Pentacam Scheimpflug imaging and Spectralis optical coherence tomography, the axial length, corneal curvature, and anterior chamber depth (ACD), as well as the thickness of the cornea, peripapillary retinal nerve fiber layer (RNFL), and macula, were compared between children and young adults and between their amblyopic and fellow eyes.
  
  
  RESULTS
  In 53 participants with hyperopic anisometropic amblyopia, there were significant differences in the anterior corneal curvature, ACD and axial length between the amblyopic and fellow eyes of all the patients. The mean central macular thickness in the amblyopic eyes was significantly thicker (P=.001) in the group aged 5 to 12 years; however, this was not the case in the group aged 13 to 42 years. There was no significant difference in average RNFL thickness in either group.
  
  
  CONCLUSIONS
  We found significantly greater mean central macular thickness in anisometropic amblyopic eyes among participants aged 5 to 12 years, but not among those who were older. Similarly, the interocular differences in axial length parameters seemed to be related to the central macular thickness differences between the amblyopic and fellow eyes in the younger group.
authors.affiliation: Department of Ophthalmology, Kayseri Training and Research Hospital Eye Clinic, Kayseri, Turkey.
authors.forename: Suleyman
authors.initials: S
authors.lastname: Demircan
authors.affiliation: Department of Ophthalmology, Kayseri Military Hospital, Kayseri, Turkey.
authors.forename: Gokcen
authors.initials: G
authors.lastname: Gokce
authors.affiliation: Department of Ophthalmology, Kayseri Training and Research Hospital Eye Clinic, Kayseri, Turkey.
authors.forename: Isa
authors.initials: I
authors.lastname: Yuvaci
authors.affiliation: Department of Ophthalmology, Kayseri Training and Research Hospital Eye Clinic, Kayseri, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Ataş
authors.affiliation: Department of Ophthalmology, Kayseri Training and Research Hospital Eye Clinic, Kayseri, Turkey.
authors.forename: Burhan
authors.initials: B
authors.lastname: Başkan
authors.affiliation: Department of Biostatistics, Erciyes University, Kayseri, Turkey.
authors.forename: Gökmen
authors.initials: G
authors.lastname: Zararsiz
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000550:Amblyopia / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D015858:Anisometropia / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000473:pathology; D005123:Eye / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D006956:Hyperopia / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D008266:Macula Lutea / Q000473:pathology; D008297:Male; D009412:Nerve Fibers / Q000473:pathology; D012160:Retina / Q000473:pathology; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D055815:Young Adult