title: [Technical scheme of real-time evaluation of traditional Chinese medicine orally disintegrating tablets].
abstract: Orally disintegrating tablets (ODT), a kind of new solid tablet that rapidly disintegrates to work in the mouth, has became the hot form of new drug research in recent years with many advantages, such as the convenient taking, a widely applicable people, fast acting, high bioavailability, good compliance, and so on. ODT has been widely used in chemical medicines, while the application of it in traditional Chinese medicines (TCMs) is still in the stage of development The development of TCMs ODT provides a new direction for the research of Chinese medicine new dosage, accelerates the pace of connecting to the world and modernization of Chinese medicine. This dosage has a broad market prospect, and its quality control and assessment standards, taste, the disintegration time in vitro and evaluation method are the key factors that affect the industrialization, standardization of Chinese medicine ODT. Therefore, this paper reviewed the characteristics, preparation, taste masking technology and quality evaluation with new technology of ODT. Meantime, numerous application examples of ODT used in traditional Chinese medicine were described. We expect to provide the reference and utilization for the development of traditional Chinese medicine orally disinteeratine tablets.
authors.forename: Dong
authors.initials: D
authors.lastname: Qin
authors.forename: Xu-dong
authors.initials: XD
authors.lastname: Chen
authors.forename: Liang
authors.initials: L
authors.lastname: Feng
authors.forename: Jun-fei
authors.initials: JF
authors.lastname: Gu
authors.forename: Jia-rui
authors.initials: JR
authors.lastname: Yuan
authors.forename: Xiao-bin
authors.initials: XB
authors.lastname: Jia
mesh_terms: D000284:Administration, Oral; D004339:Drug Compounding / Q000379:methods*; D006801:Humans; D008516:Medicine, Chinese Traditional; D012995:Solubility; D013607:Tablets / Q000008:administration & dosage* / Q000737:chemistry; D013649:Taste
chemical_list: D013607:Tablets