title: Home-based tele-supervising rehabilitation for brain infarction patients (HTRBIP): study protocol for a randomized controlled trial.
abstract: BACKGROUND
  With high morbidity, mortality and disability rate, brain infarction brings a huge economic and health burden to the whole society in China. Although some previous studies suggested that telerehabilitation may facilitate rehabilitation for stroke survivors at home, the evidence is insufficient for clinical application; additionally, as yet no trial evaluates efficacy of telerehabilitation for brain infarction patients. Therefore, more high quality trials are needed to provide practice evidence for this novel rehabilitation strategy.
  
  
  METHODS
  Based on recruitment criteria, this assessor blinded, paralleled randomized controlled trial will recruit 210 brain infarction patients. After being randomly allocated into two groups, participants will receive home-based tele-supervising rehabilitation or conventional rehabilitation. Outcome measurement will be conducted at the end of intervention and 90-day follow-up. Among which, Barthel index assessment will be considered as primary outcome measurement, secondary outcome measurements include NIHSS score, mRS score, 3-oz water swallow test and surface electromyography. Adverse events will also be recorded during the whole process of the trial for safety assessment.
  
  
  CONCLUSIONS
  The HTRBIP trial will evaluate efficacy and safety of home-based tele-supervising rehabilitation for brain infarction patients. It is expected to provide new evidence for telerehabilitation application.
  
  
  BACKGROUND
  Registration date: 17 September 2014;
  
  
  BACKGROUND
  ChiCTR-TRC-14005233.
authors.affiliation: Department of Neurology, Shanghai Number 5 Hospital, Fudan University, 801 Heqing Road, Minhang District, Shanghai, 200240, China. jinweint@sina.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Jin
authors.affiliation: Department of Neurology, Shanghai Number 5 Hospital, Fudan University, 801 Heqing Road, Minhang District, Shanghai, 200240, China. 824044742@qq.com.
authors.forename: Jing
authors.initials: J
authors.lastname: Chen
authors.affiliation: Department of Neurology, Shanghai Number 5 Hospital, Fudan University, 801 Heqing Road, Minhang District, Shanghai, 200240, China. jwshmh@sina.com.
authors.forename: Fangfang
authors.initials: F
authors.lastname: Shi
authors.affiliation: Shanghai NCC Electronic Co. Ltd, 68 NanSha Road, Minhang District, Shanghai, 200245, China. jiejiafdu@163.com.
authors.forename: Wuqing
authors.initials: W
authors.lastname: Yang
authors.affiliation: Shanghai Shenteng Information Technology Co., Ltd, Jingan District, 546 Yuyuan Road, Shanghai, 200040, China. zhangyu19810106@sina.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: China Telecom Corporation Limited Shanghai Branch, 211 Century Avenue, Pudong District, Shanghai, 200120, China. 469931323@qq.com.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Neurology, Shanghai Number 5 Hospital, Fudan University, 801 Heqing Road, Minhang District, Shanghai, 200240, China. 708815480@qq.com.
authors.forename: Wenshuai
authors.initials: W
authors.lastname: Dong
authors.affiliation: Department of Neurology, Shanghai Number 5 Hospital, Fudan University, 801 Heqing Road, Minhang District, Shanghai, 200240, China. 542174161@qq.com.
authors.forename: Yan
authors.initials: Y
authors.lastname: Jin
authors.affiliation: Shanghai NCC Electronic Co. Ltd, 68 NanSha Road, Minhang District, Shanghai, 200245, China. 419924346@qq.com.
authors.forename: Wenfeng
authors.initials: W
authors.lastname: Ma
authors.affiliation: Shanghai NCC Electronic Co. Ltd, 68 NanSha Road, Minhang District, Shanghai, 200245, China. 2723439680@qq.com.
authors.forename: Zhongju
authors.initials: Z
authors.lastname: Ma
authors.affiliation: Shanghai Shenteng Information Technology Co., Ltd, Jingan District, 546 Yuyuan Road, Shanghai, 200040, China. 2227674928@qq.com.
authors.forename: Xinli
authors.initials: X
authors.lastname: Min
authors.affiliation: China Telecom Corporation Limited Shanghai Branch, 211 Century Avenue, Pudong District, Shanghai, 200120, China. 446940863@qq.com.
authors.forename: Yin
authors.initials: Y
authors.lastname: Jin
authors.affiliation: Department of Neurology, Shanghai Number 5 Hospital, Fudan University, 801 Heqing Road, Minhang District, Shanghai, 200240, China. yonggu5thhospital@126.com.
authors.forename: Yong
authors.initials: Y
authors.lastname: Gu
authors.affiliation: Department of Neurology, Shanghai Number 5 Hospital, Fudan University, 801 Heqing Road, Minhang District, Shanghai, 200240, China. renchuancheng@outlook.com.
authors.forename: Chuancheng
authors.initials: C
authors.lastname: Ren
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020520:Brain Infarction / Q000534:rehabilitation*; D002985:Clinical Protocols; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011786:Quality Control; D000069350:Telerehabilitation