title: Solitary fibrous tumor of the pleura: morphogenesis and progression. A report of 36 cases.
abstract: OBJECTIVE
  We attempted to identify the exact point of tumor eruption of a solitary fibrous tumor of the pleura (SFTP).
  
  
  METHODS
  We morphologically classified 36 SFTPs into 5 categories. Type A showed a connection that included a bloodstream with the pleura on both sides. Type B only showed a connection that included a bloodstream with the visceral pleura, and had a non-bloodstream connection with the parietal pleura. Type C only showed a connection that included a bloodstream with the visceral pleura, and had no connection with the parietal pleura. Type D showed a non-bloodstream connection with the visceral pleura, and only showed a connection that included a bloodstream with the parietal pleura. Finally, type E had no connection with the visceral pleura, and only showed a connection that included a bloodstream with the parietal pleura. The clinicopathological profiles of the tumors were investigated according to their type.
  
  
  RESULTS
  The distribution of the 36 SFTPs was as follows: A (19 %), B (6 %), C (67 %), D (0 %) and E (8 %). The tumors categorized as type A tended to be large in size.
  
  
  CONCLUSIONS
  SFTPs commonly arise from the visceral pleura and in accordance with tumor progression they will form a non-bloodstream connection with the parietal pleura. Finally, a vascular pedicle will arise with the parietal pleura.
authors.affiliation: Division of Thoracic Surgery, National Cancer Center Hospital, 1-1 Tsukiji 5-chome, Chuo-Ku, Tokyo, 104-0045, Japan.|Division of Pathology and Clinical Laboratories, National Cancer Center Hospital, Chuo-Ku, Tokyo, Japan.
authors.forename: Tsugumasa
authors.initials: T
authors.lastname: Kamata
authors.affiliation: Division of Thoracic Surgery, National Cancer Center Hospital, 1-1 Tsukiji 5-chome, Chuo-Ku, Tokyo, 104-0045, Japan. hsakurai@ncc.go.jp.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sakurai
authors.affiliation: Division of Thoracic Surgery, National Cancer Center Hospital, 1-1 Tsukiji 5-chome, Chuo-Ku, Tokyo, 104-0045, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Nakagawa
authors.affiliation: Division of Thoracic Surgery, National Cancer Center Hospital, 1-1 Tsukiji 5-chome, Chuo-Ku, Tokyo, 104-0045, Japan.
authors.forename: Shun-ichi
authors.initials: S
authors.lastname: Watanabe
authors.affiliation: Division of Pathology and Clinical Laboratories, National Cancer Center Hospital, Chuo-Ku, Tokyo, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Tsuta
authors.affiliation: Department of Surgery, Division of General Thoracic Surgery, School of Medicine, Keio University, Shinjuku-Ku, Tokyo, Japan.
authors.forename: Hisao
authors.initials: H
authors.lastname: Asamura
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D054363:Solitary Fibrous Tumor, Pleural / Q000098:blood supply / Q000145:classification / Q000473:pathology* / Q000601:surgery; D020775:Thoracic Surgery, Video-Assisted; D013908:Thoracotomy; D016896:Treatment Outcome; D055815:Young Adult
keywords: Morphogenesis; Pleura; Solitary fibrous tumor