title: Technology to Reduce Hypoglycemia.
abstract: Hypoglycemia is a major barrier toward achieving glycemic targets and is associated with significant morbidity (both psychological and physical) and mortality. This article reviews technological strategies, from simple to more advanced technologies, which may help prevent or mitigate exposure to hypoglycemia. More efficient insulin delivery systems, bolus advisor calculators, data downloads providing information on glucose trends, continuous glucose monitoring with alarms warning of hypoglycemia, predictive algorithms, and finally closed loop insulin delivery systems are reviewed. The building blocks to correct use and interpretation of this range of available technology require patient education and appropriate patient selection.
authors.affiliation: King's College Hospital, London, UK.
authors.forename: Ester
authors.initials: E
authors.lastname: Yeoh
authors.affiliation: King's College London, London, UK pratik.choudhary@kcl.ac.uk.
authors.forename: Pratik
authors.initials: P
authors.lastname: Choudhary
mesh_terms: D000465:Algorithms; D001786:Blood Glucose / Q000032:analysis; D015190:Blood Glucose Self-Monitoring / Q000379:methods; D006801:Humans; D007003:Hypoglycemia / Q000628:therapy*; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D015918:Infusion Pumps, Implantable; D007328:Insulin / Q000008:administration & dosage*; D007332:Insulin Infusion Systems; D008991:Monitoring, Physiologic
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin
keywords: closed loop; continuous glucose monitoring; continuous subcutaneous insulin infusion; diabetes mellitus; hypoglycemia; sensor-augmented pump