title: Target-aptamer binding triggered quadratic recycling amplification for highly specific and ultrasensitive detection of antibiotics at the attomole level.
abstract: A novel electrochemical aptasensor for ultrasensitive detection of antibiotics by combining polymerase-assisted target recycling amplification with strand displacement amplification with the help of polymerase and nicking endonuclease has been reported. This work is the first time that target-aptamer binding triggered quadratic recycling amplification has been utilized for electrochemical detection of antibiotics.
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, P. R. China. chm_huangjd@ujn.edu.cn.
authors.forename: Hongzhi
authors.initials: H
authors.lastname: Wang
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
authors.forename: Su
authors.initials: S
authors.lastname: Liu
authors.forename: Jinghua
authors.initials: J
authors.lastname: Yu
authors.forename: Wei
authors.initials: W
authors.lastname: Xu
authors.forename: Yuna
authors.initials: Y
authors.lastname: Guo
authors.forename: Jiadong
authors.initials: J
authors.lastname: Huang
mesh_terms: D000667:Ampicillin / Q000032:analysis* / Q000737:chemistry; D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000737:chemistry; D052157:Aptamers, Nucleotide / Q000737:chemistry; D015374:Biosensing Techniques; D055664:Electrochemical Techniques; D004797:Enzyme-Linked Immunosorbent Assay; D057230:Limit of Detection; D008892:Milk / Q000737:chemistry; D059027:Recycling
chemical_list: D000900:Anti-Bacterial Agents; D052157:Aptamers, Nucleotide; D000667:Ampicillin