title: Recent trends in rapid environmental monitoring of pathogens and toxicants: potential of nanoparticle-based biosensor and applications.
abstract: Of global concern, environmental pollution adversely affects human health and socioeconomic development. The presence of environmental contaminants, especially bacterial, viral, and parasitic pathogens and their toxins as well as chemical substances, poses serious public health concerns. Nanoparticle-based biosensors are considered as potential tools for rapid, specific, and highly sensitive detection of the analyte of interest (both biotic and abiotic contaminants). In particular, there are several limitations of conventional detection methods for water-borne pathogens due to low concentrations and interference with various enzymatic inhibitors in the environmental samples. The increase of cells to detection levels requires long incubation time. This review describes current state of biosensor nanotechnology, the advantage over conventional detection methods, and the challenges due to testing of environmental samples. The major approach is to use nanoparticles as signal reporter to increase output rather than spending time to increase cell concentrations. Trends in future development of novel detection devices and their advantages over other environmental monitoring methodologies are also discussed.
authors.affiliation: Faculty of Environment and Resource Studies, Mahidol University, Phutthamonthon District, Nakhon Pathom 73170, Thailand.
authors.forename: Preeyaporn
authors.initials: P
authors.lastname: Koedrith
authors.affiliation: Faculty of Environment and Resource Studies, Mahidol University, Phutthamonthon District, Nakhon Pathom 73170, Thailand.
authors.forename: Thalisa
authors.initials: T
authors.lastname: Thasiphu
authors.affiliation: Department of Safety Engineering, Institute of Environmental Medicine for Green Chemistry, Dongguk University, Gyeongju, Gyeongbuk 780-714, Republic of Korea.
authors.forename: Jong-Il
authors.initials: JI
authors.lastname: Weon
authors.affiliation: Faculty of Environment and Resource Studies, Mahidol University, Phutthamonthon District, Nakhon Pathom 73170, Thailand.
authors.forename: Rattana
authors.initials: R
authors.lastname: Boonprasert
authors.affiliation: Department of Microbiology, Kasetsart University, Bangkok 10900, Thailand.
authors.forename: Kooranee
authors.initials: K
authors.lastname: Tuitemwong
authors.affiliation: Food Safety Center, Institute for Scientific and Technological Research and Services (ISTRS), King Mongkut's University of Technology Thonburi (KMUTT), Bangkok 10140, Thailand.
authors.forename: Pravate
authors.initials: P
authors.lastname: Tuitemwong
mesh_terms: D001419:Bacteria / Q000166:cytology*; D015374:Biosensing Techniques / Q000379:methods*; D004784:Environmental Monitoring / Q000379:methods*; D004785:Environmental Pollutants / Q000633:toxicity*; D004787:Environmental Pollution / Q000032:analysis*; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*
chemical_list: D004785:Environmental Pollutants