title: Treatment of failed back surgery syndrome in a forty-three-year-old man with high-dose oxycodone/naloxone.
abstract: BACKGROUND
  Failed back surgery syndrome (FBSS) is an increasing cause of chronic pain in most countries. This poses high costs to both patients and National Health Organizations.
  
  
  METHODS
  In this report, multimodal pain management based on daily high-dose oxycodone/naloxone (OXN 180/90 mg) led to reduced patient's pain score and improved quality of life.
  
  
  CONCLUSIONS
  Oxycodone/naloxone can be a good alternative for the management of FBSS when other interventional or pharmacologic strategies have failed. In this case report, higher doses than those recommended as a maximum daily ceiling (80/40 mg) were safely used in one selected patient with noncancer severe pain.
authors.affiliation: Department of Anesthesiology, Critical Care and Pain Medicine, Donostia University Hospital, San Sebastian, Spain ; Pain Relief Unit, Chronic Pain Management, Donostia University Hospital, San Sebastian, Spain.
authors.forename: Borja Mugabure
authors.initials: BM
authors.lastname: Bujedo
keywords: Cancer; Chronic Pain; Failed Back Surgery Syndrome; Opioids