title: Preeclampsia and associated factors among pregnant women attending antenatal care in Dessie referral hospital, Northeast Ethiopia: a hospital-based study.
abstract: BACKGROUND
  Preeclampsia is one of the leading causes of maternal mortality in Ethiopia. It has been increasing and linked to multiple factors, making prevention of the disease a continuous challenge. Yet few studies have been conducted in Ethiopia. This study aimed to assess the prevalence and factors associated with preeclampsia among pregnant women attending antenatal care in Dessie referral hospital, Northeast Ethiopia.
  
  
  METHODS
  A hospital-based cross-sectional study was conducted in Dessie referral hospital between August and September 2013. All pregnant women who had antenatal visit at Dessie referral hospital were included for the study. A total of 490 pregnant women were enrolled in the study. Pretested and structured questionnaire via face-to-face interview technique was used for data collection. The data were entered in to EPI info version 3.5.3 statistical software and exported to SPSS version 20 statistical package for further analysis. Descriptive statistics were used to explore the data in relation to relevant variables. Binary logistic regression analysis was employed. Odds ratio with 95% confidence intervals (CI) was computed to identify factors associated with Preeclampsia.
  
  
  RESULTS
  The prevalence of preeclampsia among pregnant women in Dessie referral hospital was found to be 8.4%. Women having family history of hypertension [Adjusted Odds Ratio (AOR) = 7.19 (95% CI 3.24-15.2)], chronic hypertension [AOR = 4.3 (95% CI 1.33-13.9)], age ≥35 years [AOR = 4.5 (95% CI 1.56-12.8)], family history of diabetes mellitus [AOR = 2.4 (95% CI 1.09-5.6)] and being unmarried [AOR = 3.03 (95% CI 1.12 - 8.2)] were found to be associated with preeclampsia.
  
  
  CONCLUSIONS
  The prevalence of preeclampsia in this hospital was lower that other studies. Having personal or family history of hypertension, older age, and family history of diabetic mellitus were factors associated with preeclampsia. Encouraging pregnant women to have health seeking behavior during pregnancy would provide a chance to diagnose preeclampsia as early as possible.
authors.affiliation: Department of Reproductive Health, Institute of Public Health, University of Gondar, Gondar, Ethiopia. agizachew@gmail.com.
authors.forename: Gizachew Assefa
authors.initials: GA
authors.lastname: Tessema
authors.affiliation: Meseret Desta Specialized Higher Clinic, Dessie, Ethiopia. abegaabebe@gmail.com.
authors.forename: Abebe
authors.initials: A
authors.lastname: Tekeste
authors.affiliation: Department of Epidemiology and Biostatistics, Institute of Public Health, University of Gondar, Gondar, Ethiopia. T_awoke@yahoo.com.
authors.forename: Tadesse Awoke
authors.initials: TA
authors.lastname: Ayele
mesh_terms: D000328:Adult; D000367:Age Factors; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D006761:Hospitals; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D016015:Logistic Models; D017533:Marital Status / Q000706:statistics & numerical data*; D016017:Odds Ratio; D010044:Outpatient Clinics, Hospital; D011225:Pre-Eclampsia / Q000453:epidemiology*; D011247:Pregnancy; D011295:Prenatal Care; D015995:Prevalence; D011446:Prospective Studies; D011507:Proteinuria / Q000453:epidemiology*; D012307:Risk Factors; D055815:Young Adult