title: Tackling oxidative stress by a direct route: a new job for HDAC inhibitors?
abstract: Olson et al. (2015) propose that some hydroxamic acid-based small molecules, already in clinical use as histone deacetylase inhibitors, may protect against oxidative stress through a direct chemical reaction of dismutation of hydrogen peroxide into water.
authors.affiliation: Department of Experimental Oncology, Academic Drug Discovery Program, and Drug Development Program, European Institute of Oncology, Via Adamello, Milan 20139, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Sartori
authors.affiliation: Department of Experimental Oncology, Academic Drug Discovery Program, and Drug Development Program, European Institute of Oncology, Via Adamello, Milan 20139, Italy; Department of Biosciences, University of Milan, Via Celoria 26, Milan 20100, Italy. Electronic address: saverio.minucci@ieo.eu.
authors.forename: Saverio
authors.initials: S
authors.lastname: Minucci
mesh_terms: D000818:Animals; D056572:Histone Deacetylase Inhibitors / Q000737:chemistry*; D006655:Histone Deacetylases / Q000737:chemistry*; D006877:Hydroxamic Acids / Q000737:chemistry*; D009474:Neurons / Q000378:metabolism*
chemical_list: D056572:Histone Deacetylase Inhibitors; D006877:Hydroxamic Acids; D006655:Histone Deacetylases