title: Poor infant inhibitory control predicts food fussiness in childhood - A possible protective role of n-3 PUFAs for vulnerable children.
abstract: Intrauterine growth restriction (IUGR) children are more impulsive towards a sweet reward and have altered feeding behavior in adulthood. We hypothesized that early life inhibitory control predicts feeding behaviors later on in childhood, and the consumption of n-3 PUFAs during infancy may protect IUGR children from developing problematic feeding behaviors. 156 children had information on the Early Childhood Behavior Questionnaire (ECBQ) at 18 months, Food Frequency Questionnaire at 48 months and Children׳s Eating Behavior Questionnaire (CEBQ) at 72 months. There was a significant negative correlation between inhibitory control at 18 months and food fussiness at 72 months. A GLM model predicting food fussiness at 72 months showed significant interaction between n-3 PUFAs, inhibitory control and IUGR, with higher intakes associated with decreased risk for fussiness in IUGR children with poor inhibitory control. Deficits in early inhibitory control predict later food fussiness, and higher intakes of n-3 PUFAs in infancy may protect IUGR children from developing such behavior later.
authors.affiliation: Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Departamento de Pediatria, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul 90035-903, Brazil.
authors.forename: Roberta Sena
authors.initials: RS
authors.lastname: Reis
authors.affiliation: Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Departamento de Pediatria, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul 90035-903, Brazil.
authors.forename: Juliana Rombaldi
authors.initials: JR
authors.lastname: Bernardi
authors.affiliation: Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Canada.
authors.forename: Meir
authors.initials: M
authors.lastname: Steiner
authors.affiliation: Department of Psychiatry and Neurology, McGill University, Douglas Mental Health University Institute, Montreal, Quèbec, Canada H4H 1R3; Singapore Institute for Clinical Sciences, 117609 Singapore.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Meaney
authors.affiliation: Department of Psychiatry, University of Toronto and Centre for Addiction and Mental Health, Toronto, Ontario, Canada M5T 1R8.
authors.forename: Robert D
authors.initials: RD
authors.lastname: Levitan
authors.affiliation: Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Departamento de Pediatria, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul 90035-903, Brazil. Electronic address: 00032386@ufrgs.br.
authors.forename: Patrícia Pelufo
authors.initials: PP
authors.lastname: Silveira
mesh_terms: D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage / Q000494:pharmacology*; D005247:Feeding Behavior / Q000187:drug effects*; D005260:Female; D005317:Fetal Growth Retardation / Q000503:physiopathology / Q000517:prevention & control; D005518:Food Preferences / Q000187:drug effects; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D013997:Time Factors
chemical_list: D015525:Fatty Acids, Omega-3
keywords: Child; Fussiness; Inhibitory control; Intrauterine Growth Restriction; n-3 PUFAs