title: Cutaneous lymphoma misdiagnosed as chronic lymphadenitis.
abstract: Cutaneous lymphomas (CLs) represent a group of lymphoproliferative disorders that can be difficult to diagnose in the early stage because they could mimic many benign inflammatory dermatoses (chronic eczema, bullous dermatosis, idiopathic erythroderma, psoriasis, lymphadenitis). Primary cutaneous B-cell lymphomas are a unique and controversial group of skin lymphomas characterised by the absence of extracutaneous manifestations at diagnosis. We present the case of a 60-year-old man with 7-month history of a growing inguinal mass/tumour, which was misdiagnosed as inguinal chronic lymphadenitis. Recognition of the correct entity, primary cutaneous diffuse large B-cell lymphoma leg type, led to an appropriate therapeutic strategy, knowing that these types of tumours behave more aggressively than other types of primary cutaneous B-cell lymphomas. The patient was discharged with rituximab + chemotherapy indication and favourable outcome. The aim of the presentation is to describe these common skin manifestations, however seen in a primary cutaneous B-cell lymphoma, which underlines the necessity of rigorous monitoring/long-term follow-up as well as exhaustive histopathological analysis for the diagnosis.
authors.affiliation: 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.
authors.forename: Mircea
authors.initials: M
authors.lastname: Munteanu
authors.affiliation: University Clinic of Dermatology and Venereology, Emergency City Hospital, Timisoara, Romania.
authors.forename: Georgiana S
authors.initials: GS
authors.lastname: Mohor
authors.affiliation: 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.|Pathology Department, Emergency City Hospital, Timisoara.
authors.forename: Flavia
authors.initials: F
authors.lastname: Baderca
authors.affiliation: 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.|University Clinic of Dermatology and Venereology, Emergency City Hospital, Timisoara, Romania.
authors.forename: Caius
authors.initials: C
authors.lastname: Solovan
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001707:Biopsy, Needle; D002908:Chronic Disease; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D005500:Follow-Up Studies; D006119:Groin; D006801:Humans; D007150:Immunohistochemistry; D008199:Lymphadenitis / Q000175:diagnosis / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*
keywords: B cell; Cutaneous lymphoma; Inflammatory dermatoses; Inguinal wound; Lymphadenitis