title: Rapidly developed squamous cell carcinoma after laser therapy used to treat chemical burn wound: a case report.
abstract: BACKGROUND
  In chronic wounds, especially burn scars, malignant tumors can arise. However, it is rare for a subacute burn injury to change to a malignant lesion within one month. Moreover, a case of squamous cell carcinoma arising from HeNe laser therapy after a chemical burn has never been reported.
  
  
  METHODS
  In this report, we examine a rare case of squamous cell carcinoma arising from HeNe laser therapy after a chemical burn. Because pathologic investigations were made from the first operation, both early detection of the squamous cell carcinoma and consideration of the HeNe laser therapy as a risk factor for the skin cancer were possible. The cancer was completely removed and reconstruction of the defect was successfully achieved in a timely manner.
  
  
  CONCLUSIONS
  Although there has as yet been no reported case of squamous cell carcinoma induced by laser therapy, it is important for clinicians to recognize both the possibility of laser-induced cancer and the rapid change of cancer, so they can provide appropriate and timely treatment.
authors.affiliation: Department of Plastic Surgery, National Health Insurance Service Ilsan Hospital, Gyeonggi, South Korea. rok0525@naver.com.
authors.forename: Hyung-Rok
authors.initials: HR
authors.lastname: Cho
authors.affiliation: Department of Plastic Surgery, National Health Insurance Service Ilsan Hospital, Gyeonggi, South Korea. frc22@daum.net.
authors.forename: Soon-Sung
authors.initials: SS
authors.lastname: Kwon
authors.affiliation: Department of Plastic Surgery, National Health Insurance Service Ilsan Hospital, Gyeonggi, South Korea. 112515@nhimc.or.kr.
authors.forename: Seum
authors.initials: S
authors.lastname: Chung
authors.affiliation: Department of Pathology, National Health Insurance Service Ilsan Hospital, Gyeonggi, Korea. jhkie88@naver.com.
authors.forename: Jeong-Hae
authors.initials: JH
authors.lastname: Kie
mesh_terms: D002057:Burns, Chemical / Q000150:complications* / Q000532:radiotherapy; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects*; D008875:Middle Aged; D011379:Prognosis; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D012973:Sodium Hypochlorite / Q000009:adverse effects; D014945:Wound Healing / Q000528:radiation effects*
chemical_list: D012973:Sodium Hypochlorite