title: Chronic inflammatory demyelinating polyneuropathy-like neuropathy as an initial presentation of Crohn's disease.
abstract: BACKGROUND
  Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare complication of Crohn's disease (CD), and it is uncertain whether it is associated with CD itself or with its treatment. We describe a case of CIDP-like neuropathy as an initial symptom of CD. The neurologic symptoms of the patient which responded partially to intravenous immunoglobulin (IVIG) recovered after resection of the appendiceal CD.
  
  
  METHODS
  A 17-year-old male had experienced three separate attacks of motor weakness and paresthesia of all four extremities over a period of 7 months. The electrophysiologic findings revealed a demyelinating sensory-motor polyneuropathy which was compatible with CIDP. However, repeated intravenous IVIG (2 g/kg) treatment gave only a partial response. Four days after the last discharge, he was diagnosed as appendiceal CD after surgical resection of a periappendiceal abscess. His neurologic symptoms and electrophysiologic findings recovered without any maintenance therapy.
  
  
  CONCLUSIONS
  CIDP-like neuropathy can be an initial presentation of CD, and recovery of the CIDP symptoms may result from resection of the CD. Clinicians should be aware of the possibility of CD in patients with intractable CIDP symptoms.
authors.affiliation: Department of Radiology, Kangbuk Samsung Medical Center, Seoul, Republic of Korea. sjkitty7592@naver.com.
authors.forename: Suji
authors.initials: S
authors.lastname: Kim
authors.affiliation: Department of Neurology, College of Medicine, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul, 133-792, Republic of Korea. go2dream@hanmail.net.
authors.forename: Seok-Jae
authors.initials: SJ
authors.lastname: Kang
authors.affiliation: Department of Neurology, College of Medicine, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul, 133-792, Republic of Korea. kiwook.oh@gmail.com.
authors.forename: Ki-Wook
authors.initials: KW
authors.lastname: Oh
authors.affiliation: Department of General Surgery, College of Medicine, Hanyang University, Seoul, Republic of Korea. bkahn@hanyang.ac.kr.
authors.forename: Byung Kyu
authors.initials: BK
authors.lastname: Ahn
authors.affiliation: Department of Gastroenterology, College of Medicine, Hanyang University, Seoul, Republic of Korea. alwayshang@hanyang.ac.kr.
authors.forename: Hang Lak
authors.initials: HL
authors.lastname: Lee
authors.affiliation: Department of Gastroenterology, College of Medicine, Hanyang University, Seoul, Republic of Korea. hands@hanyang.ac.kr.
authors.forename: Dong Soo
authors.initials: DS
authors.lastname: Han
authors.affiliation: Department of Pathology, College of Medicine, Hanyang University, Seoul, Republic of Korea. medartisan@hanyang.ac.kr.
authors.forename: Kiseok
authors.initials: K
authors.lastname: Jang
authors.affiliation: Department of Neurology, College of Medicine, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul, 133-792, Republic of Korea. aescula@hanmail.net.
authors.forename: Young Seo
authors.initials: YS
authors.lastname: Kim
mesh_terms: D018784:Abdominal Abscess / Q000209:etiology / Q000601:surgery; D000293:Adolescent; D001062:Appendectomy; D003424:Crohn Disease / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D008297:Male; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology
chemical_list: D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors