title: The metagenomic approach  and causality in virology.
abstract: Nowadays, the metagenomic approach has been a very important tool in the discovery of new viruses in environmental and biological samples. Here we discuss how these discoveries may help to elucidate the etiology of diseases and the criteria necessary to establish a causal association between a virus and a disease.
authors.forename: Silvana Beres
authors.initials: SB
authors.lastname: Castrignano
authors.forename: Teresa Keico
authors.initials: TK
authors.lastname: Nagasse-Sugahara
mesh_terms: D015984:Causality; D006801:Humans; D056186:Metagenomics; D014777:Virus Diseases / Q000209:etiology*; D014780:Viruses / Q000235:genetics* / Q000302:isolation & purification