title: Synoptic weather types and aeroallergens modify the effect of air pollution on hospitalisations for asthma hospitalisations in Canadian cities.
abstract: Pollution levels and the effect of air pollution on human health can be modified by synoptic weather type and aeroallergens. We investigated the effect modification of aeroallergens on the association between CO, O3, NO2, SO2, PM10, PM2.5 and asthma hospitalisation rates in seven synoptic weather types. We developed single air pollutant models, adjusted for the effect of aeroallergens and stratified by synoptic weather type, and pooled relative risk estimates for asthma hospitalisation in ten Canadian cities. Aeroallergens significantly modified the relative risk in 19 pollutant-weather type combinations, reducing the size and variance for each single pollutant model. However, aeroallergens did not significantly modify relative risk for any pollutant in the DT or MT weather types, or for PM10 in any weather type. Thus, there is a modifying effect of aeroallergens on the association between CO, O3, NO2, SO2, PM2.5 and asthma hospitalisations that differs under specific synoptic weather types.
authors.affiliation: Population Studies Division, Environmental Health Science & Research Bureau, Health Canada, 50 Columbine Driveway, Ottawa, ON K1A 0K9, Canada.
authors.forename: Christopher
authors.initials: C
authors.lastname: Hebbern
authors.affiliation: Population Studies Division, Environmental Health Science & Research Bureau, Health Canada, 50 Columbine Driveway, Ottawa, ON K1A 0K9, Canada. Electronic address: sabit_cakmak@hc-sc.gc.ca.
authors.forename: Sabit
authors.initials: S
authors.lastname: Cakmak
mesh_terms: D000393:Air Pollutants / Q000032:analysis*; D000397:Air Pollution / Q000032:analysis; D000485:Allergens / Q000032:analysis*; D001249:Asthma / Q000453:epidemiology*; D002170:Canada / Q000453:epidemiology; D002947:Cities / Q000453:epidemiology; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008962:Models, Theoretical; D014887:Weather
chemical_list: D000393:Air Pollutants; D000485:Allergens
keywords: Aeroallergens; Air pollution; Allergy; Asthma; Epidemiology; Hospitalisation; SSC