title: Successful management of chronic high-output ileostomy with high dose loperamide.
abstract: High-stoma output is a common problem that can lead to dehydration and electrolyte disturbance. The following report describes three patients with end ileostomy who had high-stoma outputs where conventional medical management was unsuccessful in controlling stoma output. All three patients responded to high-dose loperamide, resulting in significant clinical improvement. High-dose loperamide therapy should be considered in patients with high-stoma output who have failed conventional medical management.
authors.affiliation: St John of God Subiaco Hospital, Subiaco, Western Australia, Australia.
authors.forename: Alicia
authors.initials: A
authors.lastname: Mackowski
authors.affiliation: St John of God Subiaco Hospital, Subiaco, Western Australia, Australia.
authors.forename: Han-Kuang
authors.initials: HK
authors.lastname: Chen
authors.affiliation: St John of God Subiaco Hospital, Subiaco, Western Australia, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Levitt
mesh_terms: D000328:Adult; D000368:Aged; D000930:Antidiarrheals / Q000008:administration & dosage*; D002908:Chronic Disease; D003681:Dehydration; D003967:Diarrhea / Q000188:drug therapy* / Q000209:etiology; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005243:Feces; D005260:Female; D006801:Humans; D007081:Ileostomy / Q000009:adverse effects; D007410:Intestinal Diseases / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D008139:Loperamide / Q000008:administration & dosage*; D008297:Male; D016896:Treatment Outcome; D014883:Water-Electrolyte Imbalance / Q000209:etiology*
chemical_list: D000930:Antidiarrheals; D008139:Loperamide