title: Management of Cancer-related Cognitive Dysfunction-Conceptualization Challenges and Implications for Clinical Research and Practice.
abstract: Cancer-related cognitive dysfunction (CRCD)-especially impairments in attention and memory-constitutes a significant problem for cancer patients and survivors. Incidence rates of CRCD range from 17 to 75%. Cognitive impairment experienced by cancer patients can be severe and long-lasting. Strategies to ameliorate this condition have been hindered by difficulties in understanding the precise etiology of CRCD and a lack of consensus on appropriate and reliable assessment approaches. This article provides an overview of the magnitude of the problem and discusses pathophysiology, current theories, clinical presentation, assessment concerns, and management of CRCD.
authors.affiliation: Assistant Professor of Pediatrics, and Member, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine.
authors.forename: Pascal
authors.initials: P
authors.lastname: Jean-Pierre
keywords: Cancer; attention; cancer-related cognitive dysfunction; chemobrain; cognitive training; memory; neuropsychological rehabilitation; neuropsychology testing