title: Determination of sulfonamides in pork, egg, and chicken using multiwalled carbon nanotubes as a solid-phase extraction sorbent followed by ultra-performance liquid chromatography/tandem mass spectrometry.
abstract: Twelve sulfonamide residues, namely, sulfadiazine, sulfamerazine, sulfamethazine, sulfamonomethoxine, sulfadoxine, sulfamethoxazole, sulfaquinoxaline, sulfadimethoxine, sulfanilamide, sulfathiazole, sulfapyridine, and sulfamethizole were determined in pork tissue, chicken, and eggs by ultra-performance LC/MS/MS after SPE cleanup using multiwalled carbon nanotubes, which permitted extracted samples from animal tissue and eggs to be cleaned up under either normal phase (NP) or reversed phase (RP) conditions or both. In this method, the NP cleanup provided recoveries for nine of the 12 sulfonamides ranging from 71 to 90% and <60% for the remaining three with RSDs lower than 10%. For the RP cleanup method, the recoveries for nine of the 12 sulfonamides ranged from 70 to 94% and <60% for the remaining three with RSDs <11.1%. The two cleanup methods can complement each other to complete the simultaneous analysis of the 12 sulfonamides.
authors.affiliation: Hebei North University, College of Science, Zhangjiakou 075000, People's Republic of China.
authors.forename: Haixiang
authors.initials: H
authors.lastname: Zhao
authors.forename: Mingyu
authors.initials: M
authors.lastname: Ding
authors.forename: Yunbao
authors.initials: Y
authors.lastname: Gao
authors.forename: Wei
authors.initials: W
authors.lastname: Deng
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004350:Drug Residues / Q000032:analysis*; D004531:Eggs / Q000032:analysis*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D011200:Poultry; D000069466:Red Meat / Q000032:analysis*; D052616:Solid Phase Extraction / Q000379:methods*; D013449:Sulfonamides / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods*
chemical_list: D037742:Nanotubes, Carbon; D013449:Sulfonamides