title: Palladium-catalyzed domino C-H/N-H functionalization: an efficient approach to nitrogen-bridged heteroacenes.
abstract: Palladium-catalyzed domino C-H/N-H functionalization for the synthesis of novel nitrogen-bridged thienoacenes and 10H-benzo[4,5]thieno[3,2-b]indole derivatives from dihaloarene is reported. This domino sequence consists of initial C-H functionalization of the benzo[b]thiophene moiety, followed by Buchwald-Hartwig coupling. This transformation is also useful for the synthesis of highly π-extended compounds.
authors.affiliation: Institut für Organische Chemie, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, 55128 Mainz (Germany), Fax: (+49) 6131 3926777 http://www.chemie.uni-mainz.de/OC/AK-Waldvogel/|Division of Chemistry and Biotechnology, Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsuhsima-naka, Kita-ku, Okayama 700-8530 (Japan) http://achem.okayama-u.ac.jp/reacteng/lang/en.
authors.forename: Natsuyo
authors.initials: N
authors.lastname: Kamimoto
authors.affiliation: Institut für Organische Chemie, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, 55128 Mainz (Germany), Fax: (+49) 6131 3926777 http://www.chemie.uni-mainz.de/OC/AK-Waldvogel/
authors.forename: Dieter
authors.initials: D
authors.lastname: Schollmeyer
authors.affiliation: Division of Chemistry and Biotechnology, Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsuhsima-naka, Kita-ku, Okayama 700-8530 (Japan) http://achem.okayama-u.ac.jp/reacteng/lang/en.
authors.forename: Koichi
authors.initials: K
authors.lastname: Mitsudo
authors.affiliation: Division of Chemistry and Biotechnology, Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsuhsima-naka, Kita-ku, Okayama 700-8530 (Japan) http://achem.okayama-u.ac.jp/reacteng/lang/en.
authors.forename: Seiji
authors.initials: S
authors.lastname: Suga
authors.affiliation: Institut für Organische Chemie, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, 55128 Mainz (Germany), Fax: (+49) 6131 3926777 http://www.chemie.uni-mainz.de/OC/AK-Waldvogel/. waldvogel@uni-mainz.de.
authors.forename: Siegfried R
authors.initials: SR
authors.lastname: Waldvogel
keywords: CH activation; amination; domino reactions; heterocycles; palladium