title: Clinical features of infectious endophthalmitis in South Korea: a five-year multicenter study.
abstract: BACKGROUND
  To investigate clinical features of infectious endophthalmitis over five years in a South Korean population.
  
  
  METHODS
  Medical records of consecutive patients diagnosed with infectious endophthalmitis at eight institutions located in Gyeongsangnam-do and Pusan city between January 1, 2004 and July 31, 2010 were reviewed.
  
  
  RESULTS
  A total of 197 patients were diagnosed and treated. An average of 30.0 infectious endophthalmitis per year was developed. The annual incidence rate of postoperative endophthalmitis during 2006~2009 was 0.037%. The ratios of male to female and right to left were 50.2%: 49.8 % and 54.8%: 43.2%, respectively. Eighth decade and spring were the peak age (36.6%) and season (32.0%) to develop the infectious endophthalmitis. The most common past history in systemic disease was hypertension (40.4%), followed by diabetes (23.4%). Cataract operation (60.4%) was the most common cause, among which most of them was uneventful phacoemulsification (95.9%). Corneal laceration (51.6%) and liver abscess (42.9%) were the most common causes of traumatic and endogenous endophthalmitis, respectively. The percentages of patients with initial and final visual acuity less than counting fingers were 62.6% and 35.2%, respectively. Treatment with vitrectomy with or without intravitreal antibiotics injection was administered to 72.6% of patients, while 17.3% received intravitreal antibiotics only.
  
  
  CONCLUSIONS
  Our study revealed that the development of infectious endophthalmitis was related with seasonal variation and increased during our study period. Pars plana vitrectomy was preferred for the treatment of infectious endophthalmitis in South Korea.
authors.affiliation: Department of Ophthalmology, College of Medicine, Kosin University, 262 Gamchun-ro, Seo-gu, Busan, South Korea. oksnam1231@hanmail.net.
authors.forename: Ki Yup
authors.initials: KY
authors.lastname: Nam
authors.affiliation: Department of Ophthalmology, College of Medicine, Inje University, Pusan, South Korea. jooeun2@gmail.com.
authors.forename: Joo Eun
authors.initials: JE
authors.lastname: Lee
authors.affiliation: Department of Ophthalmology, College of Medicine, Pusan National University, Pusan, South Korea. jieun2lee@gmail.com.
authors.forename: Ji Eun
authors.initials: JE
authors.lastname: Lee
authors.affiliation: Department of Ophthalmology, College of Medicine, Dong-A University College of Medicine, Busan, South Korea. woo6775@yahoo.co.kr.
authors.forename: Woo Jin
authors.initials: WJ
authors.lastname: Jeung
authors.affiliation: Department of Ophthalmology, Maryknoll Hospital, Busan, South Korea. pjm1438@hanmail.net.
authors.forename: Jung Min
authors.initials: JM
authors.lastname: Park
authors.affiliation: Department of Ophthalmology, College of Medicine, Gyeongsang National University, Jinju, South Korea. jmpark@gsnu.ac.kr.
authors.forename: Jong Moon
authors.initials: JM
authors.lastname: Park
authors.affiliation: Department of Ophthalmology, College of Medicine, Gyeongsang National University, Jinju, South Korea. in0chung@hanmail.net.
authors.forename: In Young
authors.initials: IY
authors.lastname: Chung
authors.affiliation: Department of Ophthalmology, College of Medicine, Gyeongsang National University, Jinju, South Korea. medcabin@hanmail.net.
authors.forename: Yong Seop
authors.initials: YS
authors.lastname: Han
authors.affiliation: Department of Ophthalmology, College of Medicine, Inje University, Pusan, South Korea. ihyun@ijnc.inje.ac.kr.
authors.forename: Il Han
authors.initials: IH
authors.lastname: Yun
authors.affiliation: Department of Ophthalmology, College of Medicine, Inje University, Pusan, South Korea. maekbak@hanmail.net.
authors.forename: Hyun Wong
authors.initials: HW
authors.lastname: Kim
authors.affiliation: Department of Ophthalmology, College of Medicine, Pusan National University, Pusan, South Korea. isbyon@naver.com.
authors.forename: Ik Soo
authors.initials: IS
authors.lastname: Byon
authors.affiliation: Jung Geun Eye Hospital, Busan, South Korea. bsoum@pusan.ac.kr.
authors.forename: Boo Sup
authors.initials: BS
authors.lastname: Oum
authors.affiliation: Sungmo Eye Hospital, Busan, South Korea. heesyoon@dreamwiz.com.
authors.forename: Hee Sung
authors.initials: HS
authors.lastname: Yoon
authors.affiliation: Su Jeong Eye Clinic, Busan, South Korea. mology@hanmail.net.
authors.forename: Dong
authors.initials: D
authors.lastname: Park
authors.affiliation: Department of Preventive Medicine, College of Medicine, Kosin University, Pusan, South Korea. preventeer@hanmail.net.
authors.forename: Byeng Chul
authors.initials: BC
authors.lastname: Yu
authors.affiliation: Department of Medical Humanities and Social Medicine, Kosin University, Pusan, South Korea. ekpark@kosin.ac.kr.
authors.forename: Eun-Kee
authors.initials: EK
authors.lastname: Park
authors.affiliation: Research Institute of Life Sciences, College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea. hujang@gnu.ac.kr.
authors.forename: Hu-Jang
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: Department of Ophthalmology, College of Medicine, Kosin University, 262 Gamchun-ro, Seo-gu, Busan, South Korea. hhiatus@gmail.com.
authors.forename: Sang Joon
authors.initials: SJ
authors.lastname: Lee
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002387:Cataract Extraction; D015331:Cohort Studies; D015897:Comorbidity; D065306:Corneal Injuries / Q000453:epidemiology*; D003920:Diabetes Mellitus / Q000453:epidemiology; D009877:Endophthalmitis / Q000453:epidemiology* / Q000628:therapy; D015818:Eye Infections, Bacterial / Q000453:epidemiology* / Q000628:therapy; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D058449:Intravitreal Injections; D008100:Liver Abscess / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D012621:Seasons; D017678:Sex Distribution; D013530:Surgical Wound Infection / Q000453:epidemiology*; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods
chemical_list: D000900:Anti-Bacterial Agents