title: Penile and generalised calciphylaxis in peritoneal dialysis.
abstract: This is a rare case of penile and generalised calciphylaxis. We describe the case of a patient admitted to our hospital for septic shock and necrotic skin findings, end-stage renal disease on peritoneal dialysis. Skin findings turned out to be calciphyactic lesions. The patient was taken to the operating room for penile debridement and started on antibiotics. He was treated with sodium thiosulfate and switched to haemodialysis. Calciphylaxis is a rare disease in which the treatment is basically supportive. Further studies are needed to identify the risk factors, mechanisms of disease and treatment modalities.
authors.affiliation: Department of Internal Medicine, Cooper Medical Center, Camden, New Jersey, USA.
authors.forename: Edmond
authors.initials: E
authors.lastname: Sarkis
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002115:Calciphylaxis / Q000150:complications / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control*; D003646:Debridement / Q000379:methods; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D010409:Penile Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D006435:Renal Dialysis / Q000379:methods; D012772:Shock, Septic / Q000209:etiology; D013885:Thiosulfates / Q000008:administration & dosage
chemical_list: D000900:Anti-Bacterial Agents; D013885:Thiosulfates; C017717:sodium thiosulfate