title: High prevalence of metabolic syndrome in a mestizo group of adult patients with primary hyperparathyroidism (PHPT).
abstract: BACKGROUND
  Primary hyperparathyroidism (PHPT) and metabolic syndrome (MS) have been independently related to cardiovascular morbidities, however this association is still controversial. Mexican population has a high prevalence of metabolic syndrome, however its frequency seems to be even higher than expected in patients with PHPT.
  
  
  METHODS
  We retrospectively reviewed the charts of patients that underwent parathyroidectomy for PHPT in a referral center and used the criteria from the National Cholesterol Educational Program (NCEP)/Adult Treatment Panel III (ATP III) to define MS before surgery. We compared the characteristics between the patients with and without MS.
  
  
  RESULTS
  60 patients were analyzed, 77% were female and 72% had a single parathyroid adenoma. MS was present in 59% of the patients, this group was significantly older (57 vs. 48 years, p = 0.01) and they had lower iPTH (115 vs. 161 ng/ml, p = 0.017). Other parameters did not show differences.
  
  
  CONCLUSIONS
  MS is frequent in our population diagnosed with primary hyperparathyroidism, adverse cardiovascular parameters are common and significant differences in calcium metabolism compared to the non-MS group are present.
authors.affiliation: Endocrinology Departament Hospital de Especialidades Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Cuauhtemoc N° 330, Colonia Doctores, México City, DF, Mexico. vmendozazu@yahoo.com.
authors.forename: Victoria
authors.initials: V
authors.lastname: Mendoza-Zubieta
authors.affiliation: Endocrinology Departament Hospital de Especialidades Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Cuauhtemoc N° 330, Colonia Doctores, México City, DF, Mexico. gloriaendo@hotmail.com.
authors.forename: Gloria A
authors.initials: GA
authors.lastname: Gonzalez-Villaseñor
authors.affiliation: Endocrinology Departament Hospital de Especialidades Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Cuauhtemoc N° 330, Colonia Doctores, México City, DF, Mexico. gvargas_ortega@hotmail.com.
authors.forename: Guadalupe
authors.initials: G
authors.lastname: Vargas-Ortega
authors.affiliation: Endocrinology Departament Hospital de Especialidades Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Cuauhtemoc N° 330, Colonia Doctores, México City, DF, Mexico. baldogonzal@hotmail.com.
authors.forename: Baldomero
authors.initials: B
authors.lastname: Gonzalez
authors.affiliation: Endocrinology Experimental Investigation Unit Hospital de Especialidades Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Cuauhtemoc N° 330, Colonia Doctores, México City, DF, Mexico. clau.r2000@gmail.com.
authors.forename: Claudia
authors.initials: C
authors.lastname: Ramirez-Renteria
authors.affiliation: Endocrinology Experimental Investigation Unit Hospital de Especialidades Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Cuauhtemoc N° 330, Colonia Doctores, México City, DF, Mexico. mmercadoa@yahoo.com.
authors.forename: Moises
authors.initials: M
authors.lastname: Mercado
authors.affiliation: Endocrinology Departament Hospital de Especialidades Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Cuauhtemoc N° 330, Colonia Doctores, México City, DF, Mexico. mmol_17@yahoo.com.mx.
authors.forename: Mario A
authors.initials: MA
authors.lastname: Molina-Ayala
authors.affiliation: Endocrinology Departament Hospital de Especialidades Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Cuauhtemoc N° 330, Colonia Doctores, México City, DF, Mexico. aldo.nagisa@gmail.com.
authors.forename: Aldo
authors.initials: A
authors.lastname: Ferreira-Hermosillo
mesh_terms: D000236:Adenoma / Q000150:complications / Q000453:epidemiology; D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005006:Ethnicity / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000150:complications / Q000453:epidemiology*; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology*; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000150:complications / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies