title: Pancreatic mucinous cystadenoma with serum CA 19-9 over 1,000,000 U/mL: a case report and review of the literature.
abstract: BACKGROUND
  The diagnosis of pancreatic cystic neoplasms has become more accurate recently. In some cases, however, doubt remains regarding the lesion's malignant potential. CA 19-9 has long been identified as a reliable biomarker in differentiating pancreatic benign and malignant lesions, especially in non-jaundiced patients.
  
  
  METHODS
  We report a case of a young female who presented with a mucinous lesion in the tail of the pancreas and a serum CA 19-9 over 1,000,000 U/mL. She was taken to surgery and had a distal pancreatectomy and splenectomy. Pathology reports showed only a mucinous cystadenoma. After 1 year of follow-up, her serum CA 19-9 was normal. Following that, the work-up in these lesions, the role of the biomarker in pancreatic adenocarcinoma and in the differentiation between benign and malignant lesions is discussed.
authors.affiliation: Department of Abdominal Surgery, A. C. Camargo Cancer Center, Rua Antonio Prudente 211, Liberdade, CEP 01501-900, São Paulo, Brazil. dr.wilsoncosta@gmail.com.
authors.forename: Wilson L
authors.initials: WL
authors.lastname: Costa
authors.affiliation: Department of Abdominal Surgery, A. C. Camargo Cancer Center, Rua Antonio Prudente 211, Liberdade, CEP 01501-900, São Paulo, Brazil. hemantoan@gmail.com.
authors.forename: Henrique
authors.initials: H
authors.lastname: Mantoan
authors.affiliation: Department of Abdominal Surgery, A. C. Camargo Cancer Center, Rua Antonio Prudente 211, Liberdade, CEP 01501-900, São Paulo, Brazil. rafaelhbrito@yahoo.com.br.
authors.forename: Rafael Horácio
authors.initials: RH
authors.lastname: Brito
authors.affiliation: Department of Abdominal Surgery, A. C. Camargo Cancer Center, Rua Antonio Prudente 211, Liberdade, CEP 01501-900, São Paulo, Brazil. hsalvadorcr@gmail.com.
authors.forename: Héber S C
authors.initials: HS
authors.lastname: Ribeiro
authors.affiliation: Department of Abdominal Surgery, A. C. Camargo Cancer Center, Rua Antonio Prudente 211, Liberdade, CEP 01501-900, São Paulo, Brazil. dr.aldiniz@gmail.com.
authors.forename: Alessandro L
authors.initials: AL
authors.lastname: Diniz
authors.affiliation: Department of Abdominal Surgery, A. C. Camargo Cancer Center, Rua Antonio Prudente 211, Liberdade, CEP 01501-900, São Paulo, Brazil. andreluisgodoy@yahoo.com.br.
authors.forename: André Luís
authors.initials: AL
authors.lastname: Godoy
authors.affiliation: Department of Abdominal Surgery, A. C. Camargo Cancer Center, Rua Antonio Prudente 211, Liberdade, CEP 01501-900, São Paulo, Brazil. dr.igorfarias@gmail.com.
authors.forename: Igor Correia
authors.initials: IC
authors.lastname: Farias
authors.affiliation: Department of Surgical Pathology, A. C. Camargo Cancer Center, São Paulo, Brazil. mariadirlei@gmail.com.
authors.forename: Maria Dirlei F S
authors.initials: MD
authors.lastname: Begnami
authors.affiliation: Department of Surgical Pathology, A. C. Camargo Cancer Center, São Paulo, Brazil. fasoares@me.com.
authors.forename: Fernando Augusto
authors.initials: FA
authors.lastname: Soares
authors.affiliation: Department of Abdominal Surgery, A. C. Camargo Cancer Center, Rua Antonio Prudente 211, Liberdade, CEP 01501-900, São Paulo, Brazil. drfelipecoimbra@gmail.com.
authors.forename: Felipe J F
authors.initials: FJ
authors.lastname: Coimbra
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood*; D018395:CA-19-9 Antigen / Q000097:blood*; D018291:Cystadenoma, Mucinous / Q000097:blood / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000097:blood / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D013156:Splenectomy
chemical_list: D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen