title: Platinum(0)-Catalyzed Indolyne Insertion into Bis(pinacolato)diboron Followed by Site-Selective Suzuki-Miyaura Cross-Coupling.
abstract: Indolynes are converted into previously unprecedented indole building blocks by platinum(0)-catalyzed insertion into a symmetrically substituted boron-boron bond. The two boron sites in these indoles must be differentiated in a subsequent step, and the 6,7-bis[(pinacolato)boryl]indole was shown to undergo site-selective Suzuki-Miyaura cross-coupling with perfect C7 selectivity. The net reaction is the regioselective installation of two different substituents in the C6 and C7 positions of a 6,7-indolyne precursor.
authors.affiliation: Institut für Chemie, Technische Universität Berlin, Strasse des 17. Juni 115, 10623 Berlin, Germany.
authors.forename: Manish
authors.initials: M
authors.lastname: Pareek
authors.affiliation: Institut für Chemie, Technische Universität Berlin, Strasse des 17. Juni 115, 10623 Berlin, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Fallon
authors.affiliation: Institut für Chemie, Technische Universität Berlin, Strasse des 17. Juni 115, 10623 Berlin, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Oestreich