title: Severe Hypothyroidism From Iodine Deficiency Associated With Parenteral Nutrition.
abstract: Parenteral nutrition is crucial for supply of nutrients in children who cannot tolerate a full enteral diet. In the United States, it is not standard of care to give iodine to children dependent on parenteral nutrition, hence iodine is not routinely included in the micronutrient package. Herein, we present a case of a boy with hypothyroidism secondary to iodine deficiency after prolonged exclusive use of parenteral nutrition. Our case highlights the importance of screening for iodine deficiency and administering timely iodine supplementation in these at-risk children to prevent iatrogenic hypothyroidism.
authors.affiliation: Division of Pediatric Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio marjorie.golekoh@cchmc.org.
authors.forename: Marjorie C
authors.initials: MC
authors.lastname: Golekoh
authors.affiliation: Division of Gastroenterology, Hepatology, & Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Conrad R
authors.initials: CR
authors.lastname: Cole
authors.affiliation: Division of Pediatric Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
authors.forename: Nana-Hawa Yayah
authors.initials: NY
authors.lastname: Jones
mesh_terms: D002675:Child, Preschool; D019587:Dietary Supplements; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D007455:Iodine / Q000008:administration & dosage / Q000097:blood / Q000172:deficiency*; D008297:Male; D009752:Nutritional Status; D010288:Parenteral Nutrition / Q000009:adverse effects*; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D007455:Iodine
keywords: hypothyroidism; iodine deficiency; parenteral nutrition; urinary iodine concentration