title: Erroneous epimerization at C-22 in sapogenins.
abstract: A recent report [1] about the epimerization of steroidal sapogenins at C-22 by treatment with BF3 · OEt2 is incorrect. We proved that the epimerization of sapogenins with BF3 · OEt2 occurs at C-25 as in the case of other acid-catalyzed reactions previously studied.
authors.affiliation: Institute of Chemistry, University of Białystok, Ciołkowskiego 1K, 15-245 Białystok, Poland.
authors.forename: Izabella
authors.initials: I
authors.lastname: Jastrzębska
authors.affiliation: Institute of Chemistry, University of Białystok, Ciołkowskiego 1K, 15-245 Białystok, Poland. Electronic address: morzycki@uwb.edu.pl.
authors.forename: Jacek W
authors.initials: JW
authors.lastname: Morzycki
mesh_terms: D001880:Boranes / Q000737:chemistry; D002384:Catalysis; D004144:Diosgenin / Q000737:chemistry; D012502:Sapogenins / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001880:Boranes; D012502:Sapogenins; C021274:boron trifluoride; D004144:Diosgenin; C514916:yamogenin
keywords: 22-epi-Sapogenins; Sapogenin isomerization; Sapogenins