title: Silver-Catalyzed Tandem Hydroazidation/Alkyne-Azide Cycloaddition of Diynes with TMS-N3: An Easy Access to 1,5-Fused 1,2,3-Triazole Frameworks.
abstract: A general cascade hydroazidation and alkyne-azide 1,3-dipolar cycloaddition of diynes using silver catalysis is reported. A wide variety of diynes participated in the reaction with trimethylsilyl azide (TMS-N3) in the presence of H2O, affording the corresponding 1,5-fused-1,2,3-triazoles in good-to-excellent yields. This unprecedented protocol is operationally simple with a broad substrate scope, good functional group tolerance, and high reaction efficiency, thus providing easy access to various fused 1,2,3-triazoles.
authors.affiliation: †Department of Chemistry, Northeast Normal University, Changchun 130024, China.
authors.forename: Yongquan
authors.initials: Y
authors.lastname: Ning
authors.affiliation: †Department of Chemistry, Northeast Normal University, Changchun 130024, China.
authors.forename: Nannan
authors.initials: N
authors.lastname: Wu
authors.affiliation: §School of Chemistry and Life Science, Anshan Normal University, Anshan 114007, China.
authors.forename: Haifeng
authors.initials: H
authors.lastname: Yu
authors.affiliation: †Department of Chemistry, Northeast Normal University, Changchun 130024, China.
authors.forename: Peiqiu
authors.initials: P
authors.lastname: Liao
authors.affiliation: †Department of Chemistry, Northeast Normal University, Changchun 130024, China.
authors.forename: Xingqi
authors.initials: X
authors.lastname: Li
authors.affiliation: †Department of Chemistry, Northeast Normal University, Changchun 130024, China.|‡State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China.
authors.forename: Xihe
authors.initials: X
authors.lastname: Bi