title: Detecting Spread of Avian Influenza A(H7N9) Virus Beyond China.
abstract: During February 2013-March 2015, a total of 602 human cases of low pathogenic avian influenza A(H7N9) were reported; no autochthonous cases were reported outside mainland China. In contrast, since highly pathogenic avian influenza A(H5N1) reemerged during 2003 in China, 784 human cases in 16 countries and poultry outbreaks in 53 countries have been reported. Whether the absence of reported A(H7N9) outside mainland China represents lack of spread or lack of detection remains unclear. We compared epidemiologic and virologic features of A(H5N1) and A(H7N9) and used human and animal influenza surveillance data collected during April 2013-May 2014 from 4 Southeast Asia countries to assess the likelihood that A(H7N9) would have gone undetected during 2014. Surveillance in Vietnam and Cambodia detected human A(H5N1) cases; no A(H7N9) cases were detected in humans or poultry in Southeast Asia. Although we cannot rule out the possible spread of A(H7N9), substantial spread causing severe disease in humans is unlikely.
authors.forename: Alexander J
authors.initials: AJ
authors.lastname: Millman
authors.forename: Fiona
authors.initials: F
authors.lastname: Havers
authors.forename: A Danielle
authors.initials: AD
authors.lastname: Iuliano
authors.forename: C Todd
authors.initials: CT
authors.lastname: Davis
authors.forename: Borann
authors.initials: B
authors.lastname: Sar
authors.forename: Ly
authors.initials: L
authors.lastname: Sovann
authors.forename: Savuth
authors.initials: S
authors.lastname: Chin
authors.forename: Andrew L
authors.initials: AL
authors.lastname: Corwin
authors.forename: Phengta
authors.initials: P
authors.lastname: Vongphrachanh
authors.forename: Bounlom
authors.initials: B
authors.lastname: Douangngeun
authors.forename: Kim A
authors.initials: KA
authors.lastname: Lindblade
authors.forename: Malinee
authors.initials: M
authors.lastname: Chittaganpitch
authors.forename: Viriya
authors.initials: V
authors.lastname: Kaewthong
authors.forename: James C
authors.initials: JC
authors.lastname: Kile
authors.forename: Hien T
authors.initials: HT
authors.lastname: Nguyen
authors.forename: Dong V
authors.initials: DV
authors.lastname: Pham
authors.forename: Ruben O
authors.initials: RO
authors.lastname: Donis
authors.forename: Marc-Alain
authors.initials: MA
authors.lastname: Widdowson
mesh_terms: D000818:Animals; D001210:Asia, Southeastern / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D005843:Geography; D006801:Humans; D053124:Influenza A Virus, H5N1 Subtype; D064766:Influenza A Virus, H7N9 Subtype; D005585:Influenza in Birds / Q000453:epidemiology* / Q000635:transmission* / Q000821:virology; D007251:Influenza, Human / Q000453:epidemiology* / Q000635:transmission* / Q000821:virology; D011159:Population Surveillance; D011200:Poultry
keywords: A(H5N1); A(H7N9); Cambodia; China; Influenza; Laos; Southeast Asia; Thailand; Vietnam; poultry; respiratory infections; surveillance; viruses