title: Catalytic C-H bond addition of pyridines to allenes by a rare-Earth catalyst.
abstract: The catalytic C-H addition of pyridines to allenes has been achieved for the first time by using a half-sandwich scandium catalyst, thus constituting a straightforward and atom-economical route for the synthesis of alkenylated pyridine derivatives. The reaction proceeded regio- and stereoselectively, affording a new family of alkenylated pyridine compounds which are otherwise difficult to synthesize. A cationic Sc-η(2) -pyridyl species was isolated and confirmed to be a key catalyst species in this transformation.
authors.affiliation: Organometallic Chemistry Laboratory and RIKEN Center for Sustainable Resource Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan).
authors.forename: Guoyong
authors.initials: G
authors.lastname: Song
authors.affiliation: Organometallic Chemistry Laboratory and RIKEN Center for Sustainable Resource Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan).
authors.forename: Baoli
authors.initials: B
authors.lastname: Wang
authors.affiliation: Organometallic Chemistry Laboratory and RIKEN Center for Sustainable Resource Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan).
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Nishiura
authors.affiliation: Organometallic Chemistry Laboratory and RIKEN Center for Sustainable Resource Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan). houz@riken.jp.
authors.forename: Zhaomin
authors.initials: Z
authors.lastname: Hou
keywords: CH addition; alkenylation; allenes; pyridines; scandium