title: [Inappropriate ICD therapies: All problems solved with MADIT-RIT?].
abstract: The MADIT-RIT study represents a major trial in implantable cardioverter-defibrillator (ICD) therapy that was recently published. It highlights that different programming strategies (high rate cut-off or delayed therapy versus conventional) reduce inappropriate ICD therapies, leave syncope rates unaltered and can improve patient's survival. The study should motivate cardiologist and electrophysiologists to reconsider their individual programming strategies. However, as the study represents largely patients with ischemic or dilated cardiomyopathy for primary prevention of sudden cardiac death supplied with a dual chamber or cardiac resynchronisation therapy ICD, the results may not easily be transferable to other entities or other device types. Despite the success of the MADIT-RIT study efforts still need to be taken to further optimise device algorithms to avert inappropriate therapies. Optimised ICD therapy also includes the avoidance of unnecessary ICD shocks as well as the treatment of all aspects of the underlying cardiac disease.
authors.affiliation: Abteilung für Elektrophysiologie, Klinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München, Fakultät für Medizin, Technische Universität München, Lazarettstr. 36, 80636, München, Deutschland, Kolb@dhm.mhn.de.
authors.forename: Christof
authors.initials: C
authors.lastname: Kolb
mesh_terms: D001145:Arrhythmias, Cardiac / Q000175:diagnosis* / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D017147:Defibrillators, Implantable / Q000009:adverse effects*; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D004554:Electric Countershock / Q000009:adverse effects / Q000379:methods; D004556:Electric Injuries / Q000209:etiology* / Q000517:prevention & control*; D019317:Evidence-Based Medicine; D006801:Humans; D013813:Therapy, Computer-Assisted / Q000379:methods*; D017211:Treatment Failure; D019564:Unnecessary Procedures / Q000295:instrumentation