title: Crohn's Disease With Ovarian Granuloma: A Case Report and Review of the Literature.
abstract: We present an interesting case of a 35-year-old nulligravida with Crohn's disease with ovarian involvement. This is a rare manifestation of Crohn's disease, felt to arise from fistulization between the ovary and the intestine, most commonly the ileum. Our review of the literature revealed 11 additional case reports published in English with a total of 15 cases. The mean age at time of presentation was 33.7 years, with a predominance of right-sided involvement. This series included 10 patients with affected right ovaries, 3 with affected left ovaries, and 2 with bilateral involvement. We conclude that ovarian involvement in Crohn's disease, although rare, can exist, and that the gynecologic surgeon should be aware of this relevant disease manifestation.
authors.affiliation: Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
authors.forename: Noah
authors.initials: N
authors.lastname: Rindos
authors.affiliation: Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
authors.forename: Amanda
authors.initials: A
authors.lastname: Ecker
authors.affiliation: Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
authors.forename: Gloria
authors.initials: G
authors.lastname: Carter
authors.affiliation: Department of Obstetrics and Gynecology, Magee-Womens Hospital, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania. Electronic address: manssm@upmc.edu.
authors.forename: Suketu
authors.initials: S
authors.lastname: Mansuria
mesh_terms: D000328:Adult; D003424:Crohn Disease / Q000150:complications / Q000473:pathology* / Q000601:surgery; D004967:Estrogens / Q000008:administration & dosage; D004966:Estrogens, Conjugated (USP) / Q000008:administration & dosage; D005260:Female; D006099:Granuloma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007044:Hysterectomy; D010053:Ovary / Q000473:pathology*; D017699:Pelvic Pain / Q000209:etiology / Q000601:surgery*; D058994:Salpingectomy; D016896:Treatment Outcome
chemical_list: D004967:Estrogens; D004966:Estrogens, Conjugated (USP)
keywords: Crohn's disease; Ileo-ovarian fistula; Ovarian granuloma; Ovarian vegetable foreign matter; Pelvic pain