title: [Influence of sulfur-fumigated Paeoniae Radix Alba on contents of ten indicative components in Guizhi Decoction].
abstract: OBJECTIVE
  To investigate the influence of sulfur-fumigated Paeoniae Radix Alba on the contents of main constituents in Guizhi Decoction.
  
  
  METHODS
  HPLC was applied to the simultaneous determination and comparative analysis of ten main indicative components in Guizhi Decoction contained sun-dried and sulfur-fumigated Paeoniae Radix Alba. The analysis was performed on a Kromasil C18 column (250 mm x 4.6 mm, 5 μm) with the mobile phase consisting of acetonitrile-0.1% aqueous formic acid. The flow rate was 1.0 mL/min and the column temperature was 30 °C. The detection wavelengths were set at 254 nm and 280 nm, respectively. 20 μL was injected for analysis with gradient elution.
  
  
  RESULTS
  There were obvious differences existed between the concentrations of ten main indicative components in Guizhi Decoction contained sun-dried and sulfur-fumigated Paeoniae Radix Alba.
  
  
  CONCLUSIONS
  Sulfur-fumigated Paeoniae Radix Alba can influence the main effective constituents contained in Guizhi Decoction in quantity. The absence in the study of prescriptions affected by sulfur-fumigation is filled up through the investigation of the chemical basis of Guizhi Decoction influenced by sulfur-fumigated Paeoniae Radix Alba, and also strong evidences are offered to the further regulation and supervision of sulfur-fumigation in herbal medicines.
authors.forename: Xiao-qing
authors.initials: XQ
authors.lastname: Song
authors.forename: Hao
authors.initials: H
authors.lastname: Cai
authors.forename: Xiao
authors.initials: X
authors.lastname: Liu
authors.forename: Ke
authors.initials: K
authors.lastname: Pei
authors.forename: Ying-ying
authors.initials: YY
authors.lastname: Zhao
authors.forename: Ya-jing
authors.initials: YJ
authors.lastname: Lou
authors.forename: Feng-xian
authors.initials: FX
authors.lastname: Qiao
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005651:Fumigation; D029596:Paeonia / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry; D013455:Sulfur
chemical_list: D004365:Drugs, Chinese Herbal; C528663:guizhi decoction; D013455:Sulfur