title: Functional Gastrointestinal Disorders in Obese Patients. The Importance of the Enrollment Source.
abstract: BACKGROUND
  Obesity is frequently associated to many functional gastrointestinal disorders. The aim of the present study was to assess the prevalence of functional gastrointestinal disorders in obese patients, according to their body mass index and their recruitment source.
  
  
  METHODS
  Five hundred ninety-six obese patients (body mass index (BMI) > 30) filled out a standard questionnaire in order to evaluate the presence of functional gastrointestinal disorders. They were divided into four groups according to the Rome III criteria and their BMI: OF, obese patients from functional gastrointestinal disorder (FGID) enrollment; OO, obese patients from obesity management enrollment; MF, morbid obesity patients from FGID enrollment; and MO, morbid obesity patients from obesity management enrollment. Data analysis was performed using multivariate logistic regression.
  
  
  RESULTS
  Out of the 596 obese patients included in the present study, 183 (33 %) were complaining of FGIDs, while 413 (67 %) were consulting for obesity management. Compared to the OF group, the OO patients had a higher prevalence of females (P = 0.008) and a younger age (P < 0.001). Clinically, they reported a lower incidence of regurgitation (P = 0.044), of chest pain (P = 0.004), of irritable bowel syndrome (IBS; P = 0.035), and of functional diarrhea (P = 0.030). Compared to the MF group, the MO patients had an older age (P = 0.001), a higher BMI (P = 0.013), and clinically by a high frequency of functional dyspepsia (P = 0.006). There were symptoms that had similar prevalence in all groups (OF, OO, MF, MO) such as epigastric pain, postprandial distress, constipation, diarrhea, bloating, abdominal pain soiling, or nonspecific anorectal disorders.
  
  
  CONCLUSIONS
  This study has shown that the recruitment source accounted for marked and specific differences in the prevalence of functional gastrointestinal disorders in obesity and morbid obesity. Symptoms with similar prevalence in all groups should be systematically detected in all patients.
authors.affiliation: Physiology Department, Université René Descartes, Paris V, Paris, France. michel.bouchoucha@avc.aphp.fr.|Gastroenterology Department, Avicenne Hospital, Bobigny, France. michel.bouchoucha@avc.aphp.fr.
authors.forename: Michel
authors.initials: M
authors.lastname: Bouchoucha
authors.affiliation: Diabetes, Nutrition and Endocrinology Department, Avicenne Hospital, Bobigny, France.
authors.forename: Marinos
authors.initials: M
authors.lastname: Fysekidis
authors.affiliation: Equipe de Recherche en Epidémiologie Nutritionnelle (EREN), UFR SMBH 74 rue Marcel Cachin, 93017, Bobigny, France.
authors.forename: Chantal
authors.initials: C
authors.lastname: Julia
authors.affiliation: Gastroenterology Department, Avicenne Hospital, Bobigny, France.
authors.forename: Gheorghe
authors.initials: G
authors.lastname: Airinei
authors.affiliation: Surgical Department, Delafontaine Hospital, Saint Denis, France.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Catheline
authors.affiliation: Diabetes, Nutrition and Endocrinology Department, Avicenne Hospital, Bobigny, France.
authors.forename: Gérard
authors.initials: G
authors.lastname: Reach
authors.affiliation: Gastroenterology Department, Avicenne Hospital, Bobigny, France.
authors.forename: Robert
authors.initials: R
authors.lastname: Benamouzig
mesh_terms: D000328:Adult; D015992:Body Mass Index; D015897:Comorbidity; D005260:Female; D005767:Gastrointestinal Diseases / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology* / Q000601:surgery*; D018579:Patient Selection; D015995:Prevalence; D011795:Surveys and Questionnaires
keywords: Functional gastrointestinal disorders; Morbid obesity; Obesity; Rome criteria