title: Fatal outcome after renal transplant in a pediatric patient with Noonan syndrome.
abstract: Noonan syndrome is a congenital, common, hereditary disorder. Facial dysmorphism, growth retardation, and various heart defects are typical clinical features. In patients with minor cardiac pathology, life expectancy is normal. We report a case of renal transplant in a pediatric patient with Noonan syndrome that ended with death of the patient. Our patient presented with unexpected and refractory postoperative neurological complications that were unresponsive to intensive therapy, and the patient died because of secondary complications.
authors.affiliation: From the Department of Anesthesiology, Baskent University Faculty of Medicine, Ankara, Turkey.
authors.forename: Coskun
authors.initials: C
authors.lastname: Araz
authors.forename: Ebru
authors.initials: E
authors.lastname: Kaval
authors.forename: Adnan
authors.initials: A
authors.lastname: Torgay
authors.forename: Gokhan
authors.initials: G
authors.lastname: Moray
authors.forename: Mehmet
authors.initials: M
authors.lastname: Haberal
mesh_terms: D002545:Brain Ischemia / Q000209:etiology; D002675:Child, Preschool; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D020299:Intracranial Hemorrhage, Hypertensive / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D009634:Noonan Syndrome / Q000150:complications* / Q000175:diagnosis; D012307:Risk Factors; D016896:Treatment Outcome