title: [Clinical application of carbon nanoparticles labeled lymph node in cervical lymph node dissection with papillary thyroid cancer staged preoperatively as N0].
abstract: OBJECTIVE
  To investigate the clinical application of carbon nanoparticles staining in cervical lymph node dissection on clinical neck lymph nodes the negative (cN0 period) thyroid papillary thyroid carcinoma (PTC).
  
  
  METHODS
  This retrospective analysis comprised 100 papillary thyroid cancer patients who met inclusion criteria,and they were randomly divided into the nano-carbon group (50 cases) and control group (50 cases). They underwent lobectomy, subtotal thyroidectomy or total thyroidectomies and were given elective central compartment neck dissection (CCND). The number of detected lymph nodes in each group was summed, and pathological examination was conducted. The number of lymph nodes (dyedor not dyed) and the location of metastatic nodes were recorded separately.
  
  
  RESULTS
  In the nano-carbon group the average number of eliminated lymph nodes is significantly more than that of the control group(P<0.05). The metastasis lymph nodes in the nano-carbon group was higher than that in the control group(P<0.01). Among 100 cases, 2% had temporary vocal cord palsy, and 8% had temporary hypoparat hyroidism. No case of permanent vocal cord palsy or permanent hypocalcemia was observed.
  
  
  CONCLUSIONS
  The dyed lymph nodes can be easily identified and can be used as a guide for lymphnodes dissection in papillary thyroid carcinoma operation.
authors.forename: Qingjun
authors.initials: Q
authors.lastname: Gao
authors.forename: Daiwei
authors.initials: D
authors.lastname: Zhao
mesh_terms: D002244:Carbon; D002277:Carcinoma / Q000473:pathology / Q000601:surgery*; D002291:Carcinoma, Papillary; D004396:Coloring Agents; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes; D008207:Lymphatic Metastasis / Q000175:diagnosis*; D053758:Nanoparticles; D009333:Neck; D037981:Neck Dissection; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy; D014826:Vocal Cord Paralysis
chemical_list: D004396:Coloring Agents; D019275:Radiopharmaceuticals; D002244:Carbon