title: [Surgical treatment of differentiated thyroid carcinoma with laryngeal or tracheal invasion].
abstract: OBJECTIVE
  To analyze the clinical characters, surgical treatments and prognosis of differentiated thyroid carcinoma (DTC) with laryngeal or tracheal invasion.
  
  
  METHODS
  Forty-six cases including 33 papillary and 13 follicular were retrospectively reviewed. Thirty-four cases with tracheal invasion received conservative resection (17), window resection (11) and sleeve resection (6). One case with subglottic invasion was performed subglottic partial laryngectomy. Eleven cases with trachea-laryngeal invasion received total laryngectomy(4), 3 shave technique and 4 preservative laryngectomy.
  
  
  RESULTS
  Complications included infections and hypocalcaemia, 15 patients got permanent fistula. 5-year survival rate in cases of tracheal shave resection was 88.2%, while 63.6% in those of window resection and 83.3% in those of sleeve resection. Survival rate within 5 years of patients received preservative laryngectomy was 62. 5%. Conclusion: With meticulous preoperative examination and positive surgical treatment, both survival rate and quality of life could be improved in patients of DTC with laryngeal or tracheal invasion.
authors.forename: Xinbo
authors.initials: X
authors.lastname: Xu
authors.forename: Wenming
authors.initials: W
authors.lastname: Li
authors.forename: Tong
authors.initials: T
authors.lastname: Jin
authors.forename: Ye
authors.initials: Y
authors.lastname: Qian
authors.forename: Dongmin
authors.initials: D
authors.lastname: Wei
authors.forename: Ruijie
authors.initials: R
authors.lastname: Sun
authors.forename: Dayu
authors.initials: D
authors.lastname: Liu
authors.forename: Dapeng
authors.initials: D
authors.lastname: Lei
authors.forename: Xinliang
authors.initials: X
authors.lastname: Pan
mesh_terms: D000230:Adenocarcinoma; D006801:Humans; D007825:Laryngectomy; D007830:Larynx / Q000473:pathology*; D007831:Larynx, Artificial; D009361:Neoplasm Invasiveness; D011379:Prognosis; D011788:Quality of Life; D012189:Retrospective Studies; D015996:Survival Rate; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000601:surgery; D014132:Trachea / Q000473:pathology*