title: Memory block: a consequence of conflict resolution.
abstract: Food deprivation for 1 day in the pond snail Lymnaea stagnalis before aversive classical conditioning results in optimal conditioned taste aversion (CTA) and long-term memory (LTM) formation, whereas 5-day food deprivation before training does not. We hypothesize that snails do in fact learn and form LTM when trained after prolonged food deprivation, but that severe food deprivation blocks their ability to express memory. We trained 5-day food-deprived snails under various conditions, and found that memory was indeed formed but is overpowered by severe food deprivation. Moreover, CTA-LTM was context dependent and was observed only when the snails were in a context similar to that in which the training occurred.
authors.affiliation: Laboratory of Functional Biology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Sanuki 769-2193, Japan eito@kph.bunri-u.ac.jp.
authors.forename: Etsuro
authors.initials: E
authors.lastname: Ito
authors.affiliation: Laboratory of Functional Biology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Sanuki 769-2193, Japan.
authors.forename: Miki
authors.initials: M
authors.lastname: Yamagishi
authors.affiliation: Laboratory of Functional Biology, Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University, Sanuki 769-2193, Japan.
authors.forename: Dai
authors.initials: D
authors.lastname: Hatakeyama
authors.affiliation: Laboratory of Neurocybernetics, Research Institute for Electronic Science, Hokkaido University, Sapporo 060-0812, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Watanabe
authors.affiliation: Department of Systems Neuroscience, School of Medicine, Sapporo Medical University, Sapporo 060-8556, Japan.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Fujito
authors.affiliation: Laboratory of Comparative Physiology, Institute for Developmental Biology, RAS, Moscow 119909, Russia.
authors.forename: Varvara
authors.initials: V
authors.lastname: Dyakonova
authors.affiliation: Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada, T2N 4N1.
authors.forename: Ken
authors.initials: K
authors.lastname: Lukowiak
mesh_terms: D000818:Animals; D001362:Avoidance Learning; D003214:Conditioning, Classical; D005508:Food Deprivation; D008195:Lymnaea / Q000502:physiology*; D057567:Memory, Long-Term; D013649:Taste / Q000502:physiology
keywords: Conditioned taste aversion; Context; Food deprivation; Long-term memory; Lymnaea