title: Pediatric foreign body aspiration: A nidus for Aspergillus colonization.
abstract: We describe an immunocompetent child with bronchial fungus following foreign body aspiration. A two-year-old male presented with cough. Workup revealed air trapping and bronchoscopy showed aspirated foreign material in the right mainstem bronchus. Histopathology revealed fungal organisms suggestive of Aspergillus within an ulcer of the adjacent bronchial mucosa. Foreign body aspiration has been posited as a nidus for aspergilloma formation but is not yet described in the available English-language pediatric literature. Here, the foreign body provided a site for fungal growth in the bronchus of an otherwise healthy child. This case suggests that bronchial foreign body may pose risk of fungal colonization even in immunocompetent children.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, 925 Chestnut St., 6th Floor, Philadelphia, PA 19107, USA. Electronic address: Candace.mitchell@jefferson.edu.
authors.forename: Candace A
authors.initials: CA
authors.lastname: Mitchell
authors.affiliation: Department of Pathology, Nemours/Alfred I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE 19803, USA. Electronic address: Portia.kreiger@nemours.org.
authors.forename: Portia
authors.initials: P
authors.lastname: Kreiger
authors.affiliation: Division of Pediatric Otolaryngology, Alfred I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE 19803, USA. Electronic address: Christopher.goff@nemours.org.
authors.forename: Christopher
authors.initials: C
authors.lastname: Goff
authors.affiliation: Division of Pediatric Otolaryngology, Alfred I. duPont Hospital for Children, 1600 Rockland Rd., Wilmington, DE 19803, USA; Department of Pediatrics, Thomas Jefferson University, 1020 Walnut St., Philadelphia, PA 19107, USA. Electronic address: Udayan.shah@nemours.org.
authors.forename: Udayan K
authors.initials: UK
authors.lastname: Shah
mesh_terms: D001228:Aspergillosis / Q000175:diagnosis / Q000209:etiology*; D001980:Bronchi; D001982:Bronchial Diseases / Q000382:microbiology*; D001999:Bronchoscopy; D002675:Child, Preschool; D005547:Foreign Bodies / Q000150:complications*; D006801:Humans; D008297:Male
keywords: Aspergillus; Foreign body aspiration; Fungus; Pediatric