title: Comparison of clinical outcomes using "elevate anterior" versus "Perigee" system devices for the treatment of pelvic organ prolapse.
abstract: OBJECTIVE
  This study aims to compare clinical outcomes using the Perigee versus Elevate anterior devices for the treatment of pelvic organ prolapse (POP).
  
  
  METHODS
  One hundred and forty-one women with POP stages II to IV were scheduled for either Perigee (n = 91) or Elevate anterior device (n = 50). Preoperative and postoperative assessments included pelvic examination, urodynamic study, and a personal interview about quality of life and urinary symptoms.
  
  
  RESULTS
  Despite postoperative point C of Elevate group being significantly deeper than the Perigee group (median: -7.5 versus -6; P < 0.01), the 1-year success rates for two groups were comparable (P > 0.05). Apart from urgency incontinence, women with advanced POP experienced significant resolution of irritating and obstructive symptoms after both procedures (P < 0.05), generating the improvement in postoperative scores of Urogenital Distress Inventory (UDI-6) and Incontinence Impact Questionnaire (IIQ-7) (P < 0.01). On urodynamics, only the residual urine decreased significantly following these two procedures (P < 0.05). Women undergoing Perigee mesh experienced significantly higher visual analogue scale (VAS) scores and vaginal extrusion rates compared with the Elevate anterior procedure (P < 0.05).
  
  
  CONCLUSIONS
  With comparable success rates, the Elevate procedure has advantages over the Perigee surgery with lower extrusion rate and postoperative day 1 VAS scores.
authors.affiliation: Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Ziyou 1st Road, Kaohsiung City 80756, Taiwan ; Department of Obstetrics and Gynecology, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, 100 Ziyou 1st Road, Kaohsiung City 80756, Taiwan.
authors.forename: Cheng-Yu
authors.identifier: 0000-0002-1102-0512
authors.initials: CY
authors.lastname: Long
authors.affiliation: Department of Obstetrics and Gynecology, Kaohsiung Municipal Hsiao-Kang Hospital, Kaohsiung Medical University, 100 Ziyou 1st Road, Kaohsiung City 80756, Taiwan.
authors.forename: Chiu-Lin
authors.identifier: 0000-0002-0918-7612
authors.initials: CL
authors.lastname: Wang
authors.affiliation: Department of Obstetrics and Gynecology, Chi Mei Foundation Hospital, Tainan, Taiwan.
authors.forename: Ming-Ping
authors.initials: MP
authors.lastname: Wu
authors.affiliation: Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Ziyou 1st Road, Kaohsiung City 80756, Taiwan.
authors.forename: Chin-Hu
authors.initials: CH
authors.lastname: Wu
authors.affiliation: Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Ziyou 1st Road, Kaohsiung City 80756, Taiwan.
authors.forename: Kun-Ling
authors.initials: KL
authors.lastname: Lin
authors.affiliation: Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Ziyou 1st Road, Kaohsiung City 80756, Taiwan.
authors.forename: Cheng-Min
authors.identifier: 0000-0002-1599-7398
authors.initials: CM
authors.lastname: Liu
authors.affiliation: Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Ziyou 1st Road, Kaohsiung City 80756, Taiwan.
authors.forename: Eing-Mei
authors.initials: EM
authors.lastname: Tsai
authors.affiliation: Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, 100 Ziyou 1st Road, Kaohsiung City 80756, Taiwan.
authors.forename: Ching-Ju
authors.initials: CJ
authors.lastname: Shen
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000503:physiopathology* / Q000601:surgery*; D014563:Urodynamics; D013519:Urogenital Surgical Procedures / Q000295:instrumentation* / Q000379:methods*