title: Genomic variation across landscapes: insights and applications.
abstract: The distribution of genomic variation across landscapes can provide insights into the complex interactions between the environment and the genome that influence the distribution of species, and mediate phenotypic adaptation to local conditions. High throughput sequencing technologies now offer unprecedented power to explore these interactions, allowing powerful inferences about historical processes of colonization, gene flow and divergence, as well as the identification of loci that mediate local adaptation. These 'landscape genomic' approaches have been validated in model species and are now being applied to nonmodel organisms, including foundation species that have substantial effects on ecosystem processes. Here we review the growing field of landscape genomics from a very broad perspective. In particular, we describe the inferential power that is gained by taking a genome-wide view of genetic variation, strategies for study design to best capture adaptive variation, and how to apply this information to practical challenges, such as restoration.
authors.affiliation: Research School of Biology and Centre for Biodiversity Analysis, Australian National University, Canberra, ACT, 0200, Australia.
authors.forename: Jason G
authors.initials: JG
authors.lastname: Bragg
authors.affiliation: Research School of Biology and Centre for Biodiversity Analysis, Australian National University, Canberra, ACT, 0200, Australia.
authors.forename: Megan A
authors.initials: MA
authors.lastname: Supple
authors.affiliation: Research School of Biology and Centre for Biodiversity Analysis, Australian National University, Canberra, ACT, 0200, Australia.|School of Environmental and Rural Science, University of New England, Armidale, NSW, 2350, Australia.
authors.forename: Rose L
authors.initials: RL
authors.lastname: Andrew
authors.affiliation: Research School of Biology and Centre for Biodiversity Analysis, Australian National University, Canberra, ACT, 0200, Australia.|ARC Centre of Excellence in Plant Energy Biology, Australian National University, Canberra, ACT, 0200, Australia.
authors.forename: Justin O
authors.initials: JO
authors.lastname: Borevitz
mesh_terms: D014644:Genetic Variation; D023281:Genomics / Q000379:methods*; D008954:Models, Biological; D013045:Species Specificity
keywords: foundation species; genome-wide association studies (GWAS); landscape genomics; local adaptation; non-model organism; selection scan