title: Improvement of inflammatory dermatoses severity and quality of life in patients treated with a betamethasone valerate plaster (LIBERE study).
abstract: BACKGROUND
  A ready to use betamethasone valerate 0.1% (BMV) dressing was effective and well-tolerated by patients receiving chronic plaque psoriasis treatment.
  
  
  OBJECTIVE
  Collect data related to BMV dressing used in the context of market authorization.
  
  
  METHODS
  An observational, prospective study, including 258 patients with a maximum 4-weeks-treatment of inflammatory dermatosis with BMV 2.25 mg plaster was performed. The prescription pattern was described and the disease severity assessed using a Physician Global Assessment (PGA). Patient satisfaction as well as their quality of life (DLQI) were evaluated. Clinical evaluation was performed before and after the treatment.
  
  
  RESULTS
  The DLQI scores improved from 10.0 ± 5.4 to 3.5 ± 3.5 points (p < 0.0001) and PGA decreased from 12.5 ± 3.1 to 4.2 ± 3.0 points (p < 0.0001). The highest DLQI and PGA improvement was reported for the eczema group. Subjects reported the test dressing was better than prior therapies with 93.5% very satisfied and 90.4% satisfied.
  
  
  CONCLUSIONS
  The BMV dressing is well-tolerated and effective in the treatment of inflammatory dermatoses, improving both the objective signs of the disease as well as patients' quality of life.
authors.affiliation: a Département Dermatologie , Hôpital d'Instruction des Armées Begin , Saint-Mande , France.
authors.forename: Francois
authors.initials: F
authors.lastname: Maccari
mesh_terms: D000328:Adult; D000368:Aged; D001458:Bandages; D001624:Betamethasone Valerate / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011446:Prospective Studies; D011565:Psoriasis / Q000188:drug therapy*; D011788:Quality of Life
chemical_list: D005938:Glucocorticoids; D001624:Betamethasone Valerate
keywords: Betamethasone valerate 0.1%; DLQI; PGA; dermatoses; non-interventional study; plaster