Impact of a high-fat diet containing canola or soybean oil on body development and bone; parameters in adult male rats.
BACKGROUND
The role of the fatty acid in the prevention or progression of chronic diseases has generated significant interest on the part of researchers. Thus, our objective was to evaluate the long-term effects of high-fat diet containing soybean or canola oil on body development and bone parameters of male rats.


METHODS
After weaning, rats were grouped and fed either a control diet (7S) or a high-fat diet containing soybean (19S) or canola oil (19C). Femur and lumbar vertebra (LV4) structure were determined at 180 days by dual-energy X-ray absorptiometry and computed tomography.


RESULTS
The groups showed similar food intake, body mass and length development. The bone parameters of the 19C were similar to the control group, while the 19S showed lower bone parameters when compared to the other groups.


CONCLUSIONS
The high-fat diet containing soybean oil was unfavorable to bone structure, while the canola oil contributed bone health during the adult stage of life.
Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, 20551-030, 5th floor, Rio de Janeiro-RJ, Brazil; Experimental Nutrition Laboratory, Department of Nutrition and Dietetics, College of Nutrition, Fluminense Federal University, 24020-140, 5th floor, Niterói-RJ, Brazil.. carlosnut@ibest.com.br.
Carlos Alberto
CA
Soares da Costa
Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, 20551-030, 5th floor, Rio de Janeiro-RJ, Brazil;. santos-as@hotmail.com.
Aline
A
De Sousa dos Santos
Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, 20551-030, 5th floor, Rio de Janeiro-RJ, Brazil;. aluanasc@hotmail.com.
Aluana
A
Santana Carlos
Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, 20551-030, 5th floor, Rio de Janeiro-RJ, Brazil;. gabizinha_nut@hotmail.com.
Gabrielle de Paula
Gde P
Lopes Gonzalez
Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, 20551-030, 5th floor, Rio de Janeiro-RJ, Brazil;. rejanepontes@ig.com.br.
Rejane
R
Pontes Gaspar Reis
Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, 20551-030, 5th floor, Rio de Janeiro-RJ, Brazil;. cynthiaccs@hotmail.com.
Cynthia
C
Carneiro
Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, 20551-030, 5th floor, Rio de Janeiro-RJ, Brazil;. sandersonjpa@yahoo.com.br.
Sanderson
S
Soares Alves
Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, 20551-030, 5th floor, Rio de Janeiro-RJ, Brazil;. karinealbuquerque@yahoo.com.br.
Karine
K
Pereira Albuquerque
Experimental Nutrition Laboratory, Department of Nutrition and Dietetics, College of Nutrition, Fluminense Federal University, 24020-140, 5th floor, Niterói-RJ, Brazil.. paulacas11@gmail.com.
Paula Cristina
PC
Alves da Silva
Experimental Nutrition Laboratory, Department of Nutrition and Dietetics, College of Nutrition, Fluminense Federal University, 24020-140, 5th floor, Niterói-RJ, Brazil.. dcribeiro@id.uff.br.
Danielle
D
Cavalcante Ribeiro
Experimental Nutrition Laboratory, Department of Nutrition and Dietetics, College of Nutrition, Fluminense Federal University, 24020-140, 5th floor, Niterói-RJ, Brazil.. gilsontb@gmail.com.
Gilson
G
Teles Boaventura
Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, 20551-030, 5th floor, Rio de Janeiro-RJ, Brazil;. egbertomoura@globo.com.
Egberto Gaspar
EG
de Moura
Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, 20551-030, 5th floor, Rio de Janeiro-RJ, Brazil;. cellysaba@gmail.com.
Celly Cristina
CC
Alves do Nascimento-Saba
D015502:Absorptiometry, Photon; D000818:Animals; D001846:Bone Development / Q000187:drug effects*; D059305:Diet, High-Fat; D005229:Fatty Acids, Monounsaturated / Q000009:adverse effects*; D006128:Growth / Q000187:drug effects*; D008297:Male; D000074262:Rapeseed Oil; D051381:Rats; D017208:Rats, Wistar; D013024:Soybean Oil / Q000009:adverse effects*
D005229:Fatty Acids, Monounsaturated; D000074262:Rapeseed Oil; D013024:Soybean Oil