Radiation dose for normal organs by helical tomotherapy for lung cancer.
This study derived a simple equation of effective dose (E) versus normal organ of patients with varying body weights undergoing lung cancer treatment of helical tomotherapy (TOMO). Five tissue-equivalent and Rando phantoms were used to simulate lung cancer patients. This study then measured E and equivalent dose of organ or tissues (DT) using thermoluminescent dosimetry (TLD-100H). The TLD-100H was calibrated using TOMO 6MV photons, then inserted into phantom positions that closely corresponded with the position of the represented organs and tissues. Both E and DT were evaluated by ICRP 103. Peripheral doses varied markedly at positions close to the tumor center. The maximum statistical and total errors were 16.7-22.3%. This analytical result indicates that E of Rando and tissue-equivalent phantoms was in the ranged of 9.44±1.70 (10kg) to 4.58±0.83 (90kg)mSv/Gy. Notably, E decreased exponentially as phantom weight increased. Peripheral doses were also evaluated by TLD as a function of distance from the tumor center. Finally, experimental results are compared with those in literature. These findings will prove useful to patients, physicians, radiologists, and the public.
Department of Radiation Oncology, Chung Shan Medical University Hospital, Chung Shan Medical University, Taichung 40201,Taiwan, Republic of China; School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan, Republic of China; School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan, Republic of China.
Hsien-Chun
HC
Tseng
Department of Radiation Oncology, Chung Shan Medical University Hospital, Chung Shan Medical University, Taichung 40201,Taiwan, Republic of China; School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan, Republic of China; School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan, Republic of China; Department of Radiation Oncology, Kaohsiung Veterans General Hospital, Kaohsiung 81362, Taiwan, Republic of China.
Wen-Shan
WS
Liu
School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan, Republic of China; Department of Radiology,Taipei Medical University- Shuang Ho Hospital, New Taipei City 23561, Taiwan, Republic of China.
Hsiao-Han
HH
Tsai
Department of Radiation Oncology, Chung Shan Medical University Hospital, Chung Shan Medical University, Taichung 40201,Taiwan, Republic of China.
Hsin-Yi
HY
Chu
Department of Medical Image,Chung Shan Medical University Hospital, Chung Shan Medical University, Taichung 40201, Taiwan, Republic of China; School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan, Republic of China.
Jye-Bin
JB
Lin
School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan, Republic of China. Electronic address: ccy@csmu.edu.tw.
Chien-Yi
CY
Chen
D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy*; D011829:Radiation Dosage; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D014018:Tissue Distribution; D014057:Tomography, X-Ray Computed / Q000379:methods*; D035501:Uncertainty
D019275:Radiopharmaceuticals
Effective dose (E); Equivalent dose of organ or tissues (D(T)); Helical tomotherapy (TOMO); ICRP 103; Lung cancer; Peripheral dose; TLD; Tissue-equivalent phantom