Evaluation of nasopharyngeal microbial flora and antibiogram and its relation to otitis media with effusion.
Acute otitis media and otitis media with effusion (OME) are the main causes of hearing impairment in children which require proper treatment, mainly antibiotic therapy. Patients whom were appropriate candidates for adenoidectomy were divided into two groups regarding the presence of middle ear effusion. Adenoid tissue specimens were cultured in both groups and the bacterial flora and anti-microbial resistance pattern were determined. 72 patients were studied, 42 % had OME while 58 % did not. The following bacteria were isolated and cultured from both groups with no meaningful difference in prevalence: Streptococcus viridans (p = 0.265), Staphylococcus aureus (p = 0.72), H. influenza (p = 0.806), Entrococcus. spp (0.391), Streptococcus pneumonia (p = 0.391), nonhemolytic Streptococcus (p = 0.230). Bacterial sensitivity was similar for Amoxicillin-clavulanate (p = 0.935), Amoxicillin (p = 0.935), Cephalexin (p = 0.806), Cefixime (p = 0.391) and Azithromycin in both groups. The two groups showed no meaningful difference considering the bacterial flora of nasopharynx and their sensitivity. Bacteria in both groups were sensitive to Amoxicillin and Amoxicillin-clavulanate and resistant to Azithromycin, Cefixime and Cephalexin.
Faculty of Medicine, Sinus and Surgical Endoscopic Research Center, Imam Reza Educational Hospital, School of Medicine, Mashhad University of Medical Sciences, Taghiabad Sq., Mashhad, Iran.
Navid
N
Nourizadeh
Faculty of Medicine, Microbiology and Virology Research Center, Qaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Kiarash
K
Ghazvini
Mashhad University of Medical Sciences, Mashhad, Iran.
Vahideh
V
Gharavi
Mashhad University of Medical Sciences, Mashhad, Iran.
Niloufar
N
Nourizadeh
Faculty of Medicine, Sinus and Surgical Endoscopic Research Center, Imam Reza Educational Hospital, School of Medicine, Mashhad University of Medical Sciences, Taghiabad Sq., Mashhad, Iran. Movahedr891@mums.ac.ir.
Rahman
R
Movahed
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D009305:Nasopharynx / Q000382:microbiology*; D010034:Otitis Media with Effusion / Q000188:drug therapy / Q000382:microbiology*
D000900:Anti-Bacterial Agents
Antibiogram; Microbial flora; Otitis media with effusion