Evaluation of Neurodevelopment Using Bayley-III in Children with Cyanotic or Hemodynamically Impaired Congenital Heart Disease.
OBJECTIVE
The purpose of this study was to compare neurological development of children with cyanotic or hemodynamically impaired congenital heart disease (CHD) and healthy controls by using "Bayley Scales of Infant and Toddler Development Screening Test, Third Edition" (Bayley-III).


METHODS
Children with CHD (n = 37) and healthy controls (n = 24) aged between 1 and 41 months who were admitted to the Department of Pediatric Cardiology at our university hospital were included. The participants were assessed using Bayley-III test. All patients had cyanotic or hemodynamically impaired CHD. Weight, height, body mass index (BMI), mid-arm circumference (MAC), triceps skinfold thickness (TSF), and head circumference (HC) were measured and standard deviation scores (SDSs) were determined.


RESULTS
SDS values of weight, height, BMI, MAC, and TSF of the patients as well as HC values were significantly lower than the control group (P < .001). Compared with controls, the patients had significantly lower mean scores in all Bayley-III subscales (P < .001). We observed similar results in Bayley-III scores including the mean values of cognitive, language, and global motor scores for the CHD patients with and without cardiac surgery (P > .05).


CONCLUSIONS
This study demonstrated that children with cyanotic or hemodynamically impaired CHD have delayed neurodevelopmental outcomes compared with healthy children as assessed using Bayley-III.
Department of Pediatrics, University of Mersin Faculty of Medicine, Mersin, Turkey.|Division of Pediatric Cardiology, University of Mersin Faculty of Medicine, Mersin, Turkey.
Olgu
O
Hallioglu
Department of Pediatrics, University of Mersin Faculty of Medicine, Mersin, Turkey.
Guliz
G
Gurer
Department of Pediatrics, University of Mersin Faculty of Medicine, Mersin, Turkey.
Gulcin
G
Bozlu
Department of Pediatrics, University of Mersin Faculty of Medicine, Mersin, Turkey.|Division of Pediatric Cardiology, University of Mersin Faculty of Medicine, Mersin, Turkey.
Derya
D
Karpuz
Department of Pediatrics, University of Mersin Faculty of Medicine, Mersin, Turkey.
Khatuna
K
Makharoblidze
Department of Pediatrics, University of Mersin Faculty of Medicine, Mersin, Turkey.|Division of Pediatric Neurology, University of Mersin Faculty of Medicine, Mersin, Turkey.
Cetin
C
Okuyaz
D002675:Child, Preschool; D003071:Cognition / Q000502:physiology*; D002658:Developmental Disabilities / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000150:complications* / Q000503:physiopathology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009483:Neuropsychological Tests; D011379:Prognosis
Bayley-III Test; Congenital Heart Disease; Neurodevelopment