A meta-analysis of the long-term hearing outcomes and complications associated with atresiaplasty.
OBJECTIVE
To summarize peer-reviewed literature to evaluate the stability of long-term hearing outcomes with prolonged follow-up, and describe the incidence of complications related to atresiaplasty.


METHODS
A literature search of EMBASE, MEDLINE, PubMed, Google Scholar, and Web of Science was performed to identify studies of congenital aural atresia (CAA).


METHODS
Selected studies were published between 1997 and 2014. The 19 studies covered 964 CAA ears.


RESULTS
Stenosis and bony regrowth occurred in 14.2% (range from 0% to 30.3%). Lateralization of tympanic membrane (TM) occurred in 7.5% (range from 0% to 18.2%). Facial nerve palsy occurred in 0.5% (range from 0% to 5.0%). Six studies used Air-bone Gap (ABG) to evaluate the short-term and long-term hearing outcomes. The hearing outcomes were performed using meta-analysis, there was no significantly heterogeneity (I(2) = 0%, p = 0.997), and there was a degradation of hearing outcomes with prolonged follow-up (RR = 1.13, 95%CI: 0.98-1.30).


CONCLUSIONS
Nearly all studies focus on postoperative stenosis and bony regrowth, but some studies neglect lateralization of TM. Based on available data, which shows a lack of major complications, such as facial nerve palsy, atresiaplasty is a safe procedure. Our meta-analysis indicated that there was a degradation of hearing outcomes with prolonged follow-up.
Department of Otolaryngology - Head and Neck Surgery, Eye & ENT Hospital, Fudan University, Shanghai, China.
Chen-Long
CL
Li
Research Center, Eye & ENT Hospital, Fudan University, Shanghai, China; Hearing Medicine Key Laboratory, National Ministry of Public Health, Shanghai, China.
Pei-Dong
PD
Dai
Research Center, Eye & ENT Hospital, Fudan University, Shanghai, China; Hearing Medicine Key Laboratory, National Ministry of Public Health, Shanghai, China.
Lin
L
Yang
Department of Otolaryngology - Head and Neck Surgery, Eye & ENT Hospital, Fudan University, Shanghai, China; Hearing Medicine Key Laboratory, National Ministry of Public Health, Shanghai, China. Electronic address: ty.zhang2006@aliyun.com.
Tian-Yu
TY
Zhang
D001844:Bone Conduction; D000013:Congenital Abnormalities / Q000601:surgery*; D003251:Constriction, Pathologic; D004423:Ear / Q000002:abnormalities* / Q000601:surgery; D004424:Ear Canal / Q000473:pathology; D005158:Facial Paralysis / Q000209:etiology; D006801:Humans; D013506:Otologic Surgical Procedures / Q000009:adverse effects* / Q000379:methods
Atresiaplasty; Congenital aural atresia; Follow-up; Meta