Conservative management of a perianal rhabdomyosarcoma in a 2-year old child by Papillon's technique.
Rhabdomyosarcoma (RMS) is the most common sarcoma in paediatric patients. A perianal site is unusual and is associated with a low cure rate. The few cases of reported perianal RMS have been associated with sequelae. Here, we report the case of a 29-month-old male child who received sequential treatment by surgery, chemotherapy and radiotherapy inspired by Papillon's irradiation of adult anal/low-rectum cancers (including external beam radiotherapy in the gynecological exam position followed by brachytherapy) and who remains in complete remission 49 months post treatment with no sphincter or other anorectal disorders.
Department of Radiotherapy, Institut de Cancérologie de l'Ouest- René Gauducheau, Bd J Monod, 44800, Nantes, St-Herblain, France. charlotte.demoor@ico.unicancer.fr.|Faculty of Medicine, University of Nantes, Nantes, France. charlotte.demoor@ico.unicancer.fr.
Charlotte
C
Demoor-Goldschmidt
Department of Pediatric Oncology, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805, Villejuif, France. sophie.dumoucel@gustaveroussy.fr.
Sophie
S
Dumoucel
Department of Brachytherapy, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805, Villejuif, France. Christine.haiemeder@gustaveroussy.fr.
Christine
C
Haie-Meder
Department of Pediatric Oncology, Centre Hospitalier Universitaire, Place Ricordeau, Nantes, France. nadege.corradini@chu-nantes.fr.
Nadège
N
Corradini
Department of Radiotherapy, Institut de Cancérologie de l'Ouest- René Gauducheau, Bd J Monod, 44800, Nantes, St-Herblain, France. marc-andre.mahe@ico.unicancer.fr.|Faculty of Medicine, University of Nantes, Nantes, France. marc-andre.mahe@ico.unicancer.fr.
Marc-André
MA
Mahé
Department of Radiotherapy, Institut de Cancérologie de l'Ouest- René Gauducheau, Bd J Monod, 44800, Nantes, St-Herblain, France. stephane.supiot@ico.unicancer.fr.
Stéphane
S
Supiot
D000328:Adult; D001005:Anus Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000628:therapy; D001918:Brachytherapy; D002675:Child, Preschool; D003131:Combined Modality Therapy; D019468:Disease Management; D006801:Humans; D008297:Male; D011379:Prognosis; D012004:Rectal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000628:therapy; D012074:Remission Induction; D012208:Rhabdomyosarcoma / Q000473:pathology / Q000532:radiotherapy* / Q000628:therapy