Relationship between pre-sarcopenia, sarcopenia and bone mineral density in elderly men.
OBJECTIVE
Analyze the influence of sarcopenia in bone health of elderly men.


METHODS
This cross-sectional study evaluated 198 men aged over 60 years. Body composition was measured by dual energy X-ray absorptiometry. The BMD was measured at the femoral neck, total hip, lumbar spine and 33% radius. The diagnosis of abnormal BMD was defined for men who presented densitometric diagnosis of osteopenia or osteoporosis defined by T-score of femoral neck, total hip and lumbar spine. The pre-sarcopenia and sarcopenia were defined according to the European Working Group on Sarcopenia in Older People.


RESULTS
The group diagnosed with normal BMD, compared to the group of abnormal BMD, have significantly higher body weight, body mass index, grip strength, lean mass, fat mass, and relative appendicular skeletal muscle mass (RASM). However, after multiple linear regression analysis, we found that only the RASM, lean mass, and handgrip strength in the dominant hand influenced the variability of the BMD after adjustment for age and weight. Regression analyzes showed a positive association between greater appendicular lean mass and a smaller number of elderly patients with abnormal BMD diagnostic. The regression analyzes showed that elderly men diagnosed with pre-sarcopenia and sarcopenia had more abnormal BMD than non-sarcopenic elderly men.


CONCLUSIONS
We concluded that pre-sarcopenia and sarcopenia were associated with abnormal BMD. The lean mass, compared to fat mass, has a greater positive influence on the BMD of elderly men. This result suggests the importance of the increase in lean mass for the bone health of elderly men.
Faculdade de Ciências da Saúde, Universidade de Brasília, Brasília, DF, Brazil.
Fernando Borges
FB
Pereira
Faculdade de Ciências da Saúde, UnB, Brasília, DF, Brazil.
André Ferreira
AF
Leite
Hospital de Base de Brasília, Brasília, DF, Brazil.
Ana Patrícia
AP
de Paula
D015502:Absorptiometry, Photon; D000367:Age Factors; D000368:Aged; D015992:Body Mass Index; D001835:Body Weight / Q000502:physiology; D015519:Bone Density / Q000502:physiology*; D003430:Cross-Sectional Studies; D003720:Densitometry; D005272:Femur Neck / Q000502:physiology; D018737:Hand Strength; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis*; D012044:Regression Analysis; D055948:Sarcopenia / Q000175:diagnosis*