Computer Tomograph (CT) imaging of mandibular anatomical substrate in animal model restored with nanostructured hydroxyapatite compounds.
BACKGROUND
This study was meant to test a new type of bone graft on an animal model. This material was a nanostructured hydroxyapatite.


METHODS
the study was conducted according to Ethic Committee Regulation on animal model (Oryctolagus cuniculus - rabbit) between August and November 2014, at "Carol Davila" University of Medicine and Pharmacy, Bucharest. The animals were tested by using a CT at the level of the mandible before and after using the nanostructured hydroxyapatite.


RESULTS
The animals were CT scanned at 1, 2 and respectively 3 months, noticing a growth of the mandibular bone density. After 3 months, a bone density equal with the density of the healthy bone was noticed.


CONCLUSIONS
The use of the bone graft could be a viable alternative to available materials. The advantage was that bone recovery had a density similar to the density of the healthy bone and the cost of production was low because it was made out of Calcium azotate and monobasic ammonium phosphate.
Anatomy Department, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
R
R
Ciuluvică
Ophthalmology Department, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
S
S
Grădinaru
Institute for Nonferous and Rare Materials, Bucharest, Romania.
M
M
Popescu
Institute for Nonferous and Rare Materials, Bucharest, Romania.
R M
RM
Piticescu
Institute for Nonferous and Rare Materials, Bucharest, Romania.
R
R
Cergan
D000818:Animals; D015519:Bone Density / Q000187:drug effects; D017886:Durapatite / Q000494:pharmacology*; D021621:Imaging, Three-Dimensional; D008297:Male; D008334:Mandible / Q000033:anatomy & histology* / Q000000981:diagnostic imaging* / Q000601:surgery; D023421:Models, Animal; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D011817:Rabbits; D014057:Tomography, X-Ray Computed / Q000379:methods*
D017886:Durapatite
bone reconstruction; dental implant; hydroxyapatite; nanostructured polymers