Primary cutaneous γ/δ T-cell lymphoma. An atypical case with bone marrow granulomas.
BACKGROUND
Primary cutaneous γ/δ T-cell lymphoma is a rare variant of peripheral T-cell lymphoma which has been only recently set apart from subcutaneous panniculitis-like T-cell lymphoma and is known for its aggressive nature.


METHODS
We hereby report a case of primary cutaneous γ/δ T-cell lymphoma in a 35-year-old man with bone marrow granulomas, an unexpected feature in this lymphoma. The patient was treated with combination chemotherapy. Partial response was obtained, followed by relapse. Allogeneic stem cell transplantation was then carried out, and full remission was achieved.


CONCLUSIONS
Bone marrow granulomas can be an accompanying feature in primary cutaneous γ/δ T-cell lymphoma.
Department of Dermatology and Venereology, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;
Guy
G
Shalom
Institute of Hematology, Davidoff Center, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel.
Ronit
R
Gurion
Department of Pathology, SorokaMedical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;
Daniel
D
Benharroch
bone; cutaneous gamma/delta T-cell lymphoma; lymphoma; peripheral T-cell lymphoma; subcutaneous panniculitis-like T-cell lymphoma; ulcer