CT features of lung scar cancer.
OBJECTIVE
To explore the CT features of lung scar cancer (LSC).


METHODS
CT images of 41 LSCs and 66 non-LSCs were retrospectively compared in terms of location, size, shape, border, speculation, lobulation, pleural indentation, surrounding ground-glass opacification (sGGO), vessel convergence, vacuolation, calcification and satellite opacification.


RESULTS
Thirty-eight LSCs were histopathologically identified as adenocarcinoma. The LSCs and non-LSCs were located 8.73±8.65 and 12.55±10.67 mm from the pleura, respectively. The mean lesion sizes (3-D ratios) in the initial LSC, pre-surgical LSC and non-LSC images were 24.28±6.29 (0.33±0.65), 32.23±8.14 (0.60±0.18) and 23.24±3.73 (0.35±0.61) mm, respectively. The initial and pre-surgical LSC images showed significant differences in speculation and sGGO (P<0.05). Significant differences were also noted in vacuolation, vessel convergence and sGGO between the pre-surgical LSC and the non-LSC images (P<0.05) and in vacuolation between the initial LSC and the non-LSC images (P<0.05).


CONCLUSIONS
Despite similar CT features of LSCs and non-LSCs, the early detection and diagnosis of LSCs is possible by studying scar-tissue changes such as enlargement and sGGO associated with well-defined lesion borders in follow-up CT images.
1 Department of Radiology, 2 Diagnostic and Treatment Center of Small Lung Nodules, 3 Department of Pathology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.
Feng
F
Gao
1 Department of Radiology, 2 Diagnostic and Treatment Center of Small Lung Nodules, 3 Department of Pathology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.
Xiaojun
X
Ge
1 Department of Radiology, 2 Diagnostic and Treatment Center of Small Lung Nodules, 3 Department of Pathology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.
Ming
M
Li
1 Department of Radiology, 2 Diagnostic and Treatment Center of Small Lung Nodules, 3 Department of Pathology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.
Xiangpeng
X
Zheng
1 Department of Radiology, 2 Diagnostic and Treatment Center of Small Lung Nodules, 3 Department of Pathology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.
Li
L
Xiao
1 Department of Radiology, 2 Diagnostic and Treatment Center of Small Lung Nodules, 3 Department of Pathology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.
Guozhen
G
Zhang
1 Department of Radiology, 2 Diagnostic and Treatment Center of Small Lung Nodules, 3 Department of Pathology, Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China.
Yanqing
Y
Hua
Lung neoplasms; X-ray computed; adenocarcinoma; cicatrix; tomography