A case-control study of stomach cancer in relation to Camellia sinensis in China.
OBJECTIVE
The purpose of our study was to investigate the association between green tea (Camellia sinensis) drinking habits and risk of stomach cancer in China.


METHODS
A 1:2 matched hospital-based case-control study including 160 cases and 320 controls was conducted. A self-designed questionnaire was used to collect information on possible risk factors of stomach cancer, and to assess the green tea drinking habit. Conditional logistic regression was used to calculate odds ratios (ORs) and corresponding 95% confidence intervals (CIs).


RESULTS
Our study proposed that green tea was associated with risk of stomach cancer. Regular drinking (OR = 0.72), larger amount of consumption (≥35 g/week) (OR = 0.53) were protective factors. Among regular tea drinkers, lower temperature and longer interval between tea being poured and drunk also reduced the risk. Moreover, a strong agreement was found between temperature at which tea was drunk and tea interval (Correlation coefficient p value = 0.73).


CONCLUSIONS
Habits of green tea drinking, including regular drinking, larger amount of consumption, lower temperature and longer interval were strongly associated with a lower risk of stomach cancer.
Department of Surgery, Liaoning Cancer Hospital and Institute, Shenyang, 110042, China. Electronic address: 13514212975@163.com.
Yue
Y
Wang
Department of Epidemiology, Zhengzhou University, Zhengzhou, China.
Hong
H
Duan
Institute of Public Health, University of California, San Francisco, USA.
Helen
H
Yang
D000328:Adult; D000368:Aged; D028241:Camellia sinensis; D016022:Case-Control Studies; D004327:Drinking Behavior; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy / Q000379:methods; D013274:Stomach Neoplasms / Q000517:prevention & control*; D013662:Tea; D013696:Temperature; D016896:Treatment Outcome
D013662:Tea
Camellia sinensis; Case-control study; China; Green tea