Roles of Natural Compounds from Medicinal Plants in Cancer Treatment: Structure and Mode of Action at Molecular Level.
Every year, cancer takes the life of millions of people. Conventional treatments have produced unsatisfactory results for some types of cancer, and the side effects are extensive, leading to a shift in the focus of treatment towards alternative medicines. Indeed, medicinal plants have long been investigated by scientists for their anti-cancer properties. Some phytochemicals that are important active constituents of plants, including catechins, ursolic acid, silymarin, glycyrrhizin, ellagic acid, gallic acid and various types of flavonoids, have shown promise in future cancer management. The current review covers various aspects of cancer treatment based on medicinal plants at molecular level and sheds light on their structures and modes of action.
Mahmood
M
Rasool
Arif
A
Malik
Abdul
A
Manan
Mahwish
M
Arooj
Mahmood Husain
MH
Qazi
Mohammad Amjad
MA
Kamal
Ishfaq Ahmed
IA
Sheikh
Siew Hua
SH
Gan
Muhammad
M
Asif
Center of Excellence in Genomic Medicine Research (CEGMR), Post Box No. 80216, King Abdulaziz University, Jeddah, 21589 Saudi Arabia. mimrannaseer@yahoo.com.
Muhammad Imran
MI
Naseer
D000818:Animals; D001688:Biological Products / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D063646:Carcinogenesis / Q000187:drug effects; D018432:Drug Resistance, Multiple / Q000187:drug effects; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology; D064209:Phytochemicals / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D010946:Plants, Medicinal / Q000737:chemistry*
D001688:Biological Products; D064209:Phytochemicals