Development of double-layer coupled coil for improving S/N in 7 T small-animal MRI.
The purpose of this study was to develop a new double-layer coupled (DLC) surface radiofrequency (RF) coil using a combination of single-layer planar (SLP) and single-layer circular (SLC) coils, for enhancement of magnetic flux (B1 ) sensitivity and RF penetration in 7 T rat-body magnetic resonance imaging (MRI). The proposed DLC surface coil was fabricated according to an electromagnetic (EM) simulation and validated based on the B1 distribution and bench measurements. The DLC coil performance was quantitatively evaluated based on the signal-to-noise ratio (S/N) and coil-response signal intensity curves in phantom and in vivo rat-body images. In the computational EM calculation and 7 T in vivo experimental results, the DLC surface coil clearly showed an increased S/N and higher RF transmit (B1 (+) ) profiles, compared to those of the SLP and SLC coils. While all surface coils displayed a rapid decrease in the MR signal from the near-coil region to the subject, the results reveal that the DLC coil concept may be used to provide sufficient RF penetration and high S/N and degrees of freedom for use in partial body imaging for 7 T ultra-high-field small-animal MRI.
Center for Molecular and Cellular Imaging, Samsung Biomedical Research Institute, Seoul, Korea.
Kyoung-Nam
KN
Kim
Center for Molecular and Cellular Imaging, Samsung Biomedical Research Institute, Seoul, Korea.
Jeung-Hoon
JH
Seo
Center for Molecular and Cellular Imaging, Samsung Biomedical Research Institute, Seoul, Korea.
Sang-Doc
SD
Han
Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.|Department of Health Science and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Korea.
Phil
P
Heo
Center for Molecular and Cellular Imaging, Samsung Biomedical Research Institute, Seoul, Korea.
Geun Ho
GH
Im
Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.|Department of Health Science and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Korea.
Jung Hee
JH
Lee
7 T; MRI; double-layer coupled coil; single-layer circular coil; single-layer planar coil