Report of a successful ongoing pregnancy as a result of IMSI with assisted oocyte activation.
We report a successful ongoing pregnancy obtained in a case of total globozoospermia after intracytoplasmic morphologically selected sperm injection (IMSI) with oocyte activation. The first semen analysis on investigation showed partial globozoospermia. However, under high magnification assessment at oocyte retrieval only round headed sperm were observed. Considering the high risk of a complete failure to fertilize from IMSI the couple gave written informed consent to the use of oocyte activation media post IMSI. One embryo fertilized, developed to a hatching blastocyst and was transferred resulting in an ongoing pregnancy. This successful outcome shows the use of IMSI is useful in the evaluation of total globozooozpermia and therefore aids in the justification of the use of oocyte activation media.
Obstetrics and Gynecology Department, University of Medicine and Pharmacy, Iasi, Romania. bogdandoroftei@gmail.com.|Teaching Hospital Obgyn "Cuza Voda", Iasi, Romania. bogdandoroftei@gmail.com.|Origyn Fertility Center, Iasi, Romania. bogdandoroftei@gmail.com.
Bogdan
B
Doroftei
Origyn Fertility Center, Iasi, Romania. mihaelazlei@gmail.com.|Regional Institute of Oncology, Iasi, Romania. mihaelazlei@gmail.com.|Laboratory of Molecular Biology, Regional Institute of Oncology, Romania, 2-4 Berthelot Street, postal code 700483, Iasi, Romania. mihaelazlei@gmail.com.
Mihaela
M
Zlei
Teaching Hospital Obgyn "Cuza Voda", Iasi, Romania. gabi.ginecologie@gmail.com.|Origyn Fertility Center, Iasi, Romania. gabi.ginecologie@gmail.com.
Gabriela
G
Simionescu
Teaching Hospital Obgyn "Cuza Voda", Iasi, Romania. dr.radu.maftei@gmail.com.|Origyn Fertility Center, Iasi, Romania. dr.radu.maftei@gmail.com.
Radu
R
Maftei
Origyn Fertility Center, Iasi, Romania. simona.cumpata@gmail.com.
Simona
S
Cumpata
Origyn Fertility Center, Iasi, Romania. emersongerri@gmail.com.
Geraldine
G
Emerson
D000328:Adult; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000473:pathology / Q000628:therapy*; D008297:Male; D009865:Oocytes / Q000166:cytology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D027724:Reproductive Techniques, Assisted; D055101:Semen Analysis; D013077:Sperm Head; D020554:Sperm Injections, Intracytoplasmic; D013094:Spermatozoa / Q000002:abnormalities*