Introduction: Childhood implications of parental aging.
Men and women are increasingly delaying childbearing to the late 30s, the 40s and beyond. The implications of this societal change on childhood health and well-being have only recently been a focus of research. There are known increased perinatal risks associated with increasing maternal age, while paternal age seems to have a potentially greater negative impact on childhood health. Understanding the mechanisms underlying the aging of sperm and eggs, and how these changes impact offspring, is a critical next step as we work to help patients build healthy families.
Division of Reproductive Endocrinology and Infertility, University of California, San Francisco, California. Electronic address: cedarsm@obgyn.ucsf.edu.
Marcelle I
MI
Cedars
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003072:Cognition Disorders / Q000453:epidemiology* / Q000517:prevention & control; D002658:Developmental Disabilities / Q000453:epidemiology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007246:Infertility / Q000453:epidemiology* / Q000517:prevention & control; D008297:Male; D008423:Maternal Age; D008875:Middle Aged; D009422:Nervous System Diseases / Q000453:epidemiology* / Q000517:prevention & control; D010331:Paternal Age; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000517:prevention & control; D011256:Pregnancy Outcome; D018566:Pregnancy, High-Risk; D015995:Prevalence; D043762:Reproductive Behavior / Q000706:statistics & numerical data; D018570:Risk Assessment; D012307:Risk Factors
IVF; advanced maternal age; advanced paternal age