Early detection of sporadic pancreatic cancer: strategic map for innovation--a white paper.
Innovation leading to significant advances in research and subsequent translation to clinical practice is urgently necessary in early detection of sporadic pancreatic cancer. Addressing this need, the Early Detection of Sporadic Pancreatic Cancer Summit Conference was conducted by Kenner Family Research Fund in conjunction with the 2014 American Pancreatic Association and Japan Pancreas Society Meeting. International interdisciplinary scientific representatives engaged in strategic facilitated conversations based on distinct areas of inquiry: Case for Early Detection: Definitions, Detection, Survival, and Challenges; Biomarkers for Early Detection; Imaging; and Collaborative Studies. Ideas generated from the summit have led to the development of a Strategic Map for Innovation built upon 3 components: formation of an international collaborative effort, design of an actionable strategic plan, and implementation of operational standards, research priorities, and first-phase initiatives. Through invested and committed efforts of leading researchers and institutions, philanthropic partners, government agencies, and supportive business entities, this endeavor will change the future of the field and consequently the survival rate of those diagnosed with pancreatic cancer.
From the *Kenner Family Research Fund, New York, NY; †Department of Medicine, Mayo Clinic, Rochester, MN; ‡Sawgrass Leadership Institute, Ponte Vedra Beach, FL; and §Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.
Barbara J
BJ
Kenner
Suresh T
ST
Chari
Deborah F
DF
Cleeter
Vay Liang W
VL
Go
D014408:Biomarkers, Tumor / Q000235:genetics / Q000378:metabolism; D035843:Biomedical Research / Q000458:organization & administration*; D001706:Biopsy; D021441:Carcinoma, Pancreatic Ductal / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism / Q000401:mortality / Q000473:pathology / Q000628:therapy; D003299:Cooperative Behavior; D003952:Diagnostic Imaging; D004059:Diffusion of Innovation; D055088:Early Detection of Cancer / Q000379:methods; D006801:Humans; D033183:Interdisciplinary Communication; D007391:International Cooperation; D025202:Molecular Diagnostic Techniques; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism / Q000401:mortality / Q000473:pathology / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis
D014408:Biomarkers, Tumor