Retinal vessel diameters and their correlation with retinal nerve fiber layer thickness in patients with pseudoexfoliation syndrome.
OBJECTIVE
To compare retinal artery-vein diameters (RAVDs) of patients with pseudoexfoliation (PSX) syndrome with healthy controls and investigate the correlations between retinal nerve fiber layer (RNFL) thickness parameters and RAVDs.


METHODS
Seventeen eyes with PSX and 17 eyes of age-matched controls were included in the study. All participants underwent routine ophthalmological examination, Humphrey visual field and RNFL examination by using Stratus OCT. Retinal images were obtained by using a retinal camera (Topcon 501X). RAVDs were measured from inferior nasal, inferior temporal, superior nasal and superior temporal arcuates by using IMAGEnet software. Superior, inferior, nasal, temporal and average RNFL thicknesses were recorded. RAVDs and RNFL parameters in groups and correlations were analyzed by Mann-Whitney U and Spearmann correlation tests.


RESULTS
Only inferior quadrant and average RNFL thickness were detected thinner in the PSX group compared with control group (P=0.009, P=0.038, respectively). No statistically significant difference regarding RAVDs was found between two groups.


CONCLUSIONS
RAVDs seems to be comparable in the PSX and control group. RNFL is thinner in the inferior quadrant in the PSX group. RNFL thickness and RAVDs show significant correlations in both groups. This correlation doesn't seem to be specific to PSX.
Department of Ophthalmology, Gazi University Medical School, Ankara 06500, Turkey.
Mehmet Cuneyt
MC
Ozmen
Department of Ophthalmology, Gazi University Medical School, Ankara 06500, Turkey.
Zeynep
Z
Aktas
Department of Ophthalmology, Gazi University Medical School, Ankara 06500, Turkey.
Burcin Kepez
BK
Yildiz
Department of Ophthalmology, Gazi University Medical School, Ankara 06500, Turkey.
Murat
M
Hasanreisoglu
Department of Ophthalmology, Gazi University Medical School, Ankara 06500, Turkey.
Berati
B
Hasanreisoglu
pseudoexfoliation; retinal artery-vein diameters; retinal nerve fiber layer thickness