Effective treatment with Dabrafenib and Trametinib for a BRAF-mutated metastatic dedifferentiated malignant spindle cell neoplasm.
Department of Dermatology, Hospital Clinico Universitario de Valencia, Valencia, Spain.
I
I
Escandell
Department of Pathology, Hospital Clinico Universitario de Valencia, Valencia, Spain.
M
M
Cabezas
Department of Dermatology, Hospital Clinico Universitario de Valencia, Valencia, Spain.
J M
JM
Martín
Department of Pathology, Hospital Clinico Universitario de Valencia, Valencia, Spain.
L
L
Terradez
Department of Dermatology, Hospital Clinico Universitario de Valencia, Valencia, Spain.
M I
MI
Pinazo
D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D008545:Melanoma / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D009154:Mutation; D009362:Neoplasm Metastasis; D010091:Oximes / Q000627:therapeutic use*; D011728:Pyridones / Q000627:therapeutic use*; D011744:Pyrimidinones / Q000627:therapeutic use*
D000970:Antineoplastic Agents; D007093:Imidazoles; D010091:Oximes; D011728:Pyridones; D011744:Pyrimidinones; C560077:trametinib; C561627:dabrafenib