Cluster of serogroup W-135 meningococcal disease in 3 military recruits.
We describe a group of 3 cases of invasive meningococcal disease that occurred in a military training camp in April 2011. All three patients were hospitalized. Ultimately, two patients recovered and one died. One patient had meningitis, one patient had septicemia and meningitis, and the other had no definite septicemia or meningitis. Neisseria meningitidis serogroup W-135 was detected in the serum and cerebrospinal fluid (CSF) of all patients by real-time polymerase chain reaction. In the one case of mortality, two strains were isolated from the patient's blood and CSF. Using multilocus sequence typing analysis, these strains were identified as a novel sequence type, ST-8912. Special attention is required for the meningococcal disease in military camp because the military personnels are in high risk of contact transmission.
Division of Infectious Diseases, Konyang University College of Medicine, Daejeon, Korea.
Yu Mi
0000-0002-7983-5152
YM
Jo
Division of Bacterial Respiratory Infections, Centers for Infectious Diseases, National Institute of Health, Korea Centers for Disease Control and Prevention, Cheongwon, Korea.
Song-Mee
0000-0001-9045-1275
SM
Bae
Division of Bacterial Respiratory Infections, Centers for Infectious Diseases, National Institute of Health, Korea Centers for Disease Control and Prevention, Cheongwon, Korea.
Yeon-Ho
0000-0002-8772-8461
YH
Kang
D004269:DNA, Bacterial / Q000097:blood / Q000134:cerebrospinal fluid; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D008297:Male; D008581:Meningitis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D008889:Military Personnel; D058885:Multilocus Sequence Typing; D038582:Neisseria meningitidis, Serogroup W-135 / Q000235:genetics / Q000302:isolation & purification*; D060888:Real-Time Polymerase Chain Reaction; D018805:Sepsis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D055815:Young Adult
D004269:DNA, Bacterial
Meningococcal Infections; Military Personnel; Neisseria meningitides, Serogroup W-135