New method for the rapid extraction of natural products: efficient isolation of shikimic acid from star anise.
A new, practical, rapid, and high-yielding process for the pressurized hot water extraction (PHWE) of multigram quantities of shikimic acid from star anise (Illicium verum) using an unmodified household espresso machine has been developed. This operationally simple and inexpensive method enables the efficient and straightforward isolation of shikimic acid and the facile preparation of a range of its synthetic derivatives.
†School of Physical Sciences - Chemistry and ‡Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Hobart, Tasmania 7001, Australia.
Jeremy
J
Just
†School of Physical Sciences - Chemistry and ‡Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Hobart, Tasmania 7001, Australia.
Bianca J
BJ
Deans
†School of Physical Sciences - Chemistry and ‡Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Hobart, Tasmania 7001, Australia.
Wesley J
WJ
Olivier
†School of Physical Sciences - Chemistry and ‡Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Hobart, Tasmania 7001, Australia.
Brett
B
Paull
†School of Physical Sciences - Chemistry and ‡Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Hobart, Tasmania 7001, Australia.
Alex C
AC
Bissember
†School of Physical Sciences - Chemistry and ‡Australian Centre for Research on Separation Science (ACROSS), University of Tasmania, Hobart, Tasmania 7001, Australia.
Jason A
JA
Smith
D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification*; D029523:Illicium / Q000737:chemistry*; D008968:Molecular Conformation; D012765:Shikimic Acid / Q000737:chemistry / Q000302:isolation & purification*
D001688:Biological Products; D012765:Shikimic Acid