[New predictive parameters of nasal polyposis: neutrophil to lymphocyte ratio and platelet to lymphocyte ratio].
OBJECTIVE
This study aims to investigate the correlations between nasal polyposis (NP) and NP density with neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR).


METHODS
The study included 105 patients (72 males, 33 females; mean age 41.33±12.85 years; range 16 to 63 years) diagnosed as NP (NP group) and 83 healthy individuals (54 males, 29 females; mean age 44.01±8.50 years; range 18 to 62 years) (control group). Nasal polyposis density score was calculated with preoperative Lund-Mackay computed tomography grading system. Neutrophil to lymphocyte and PLR ratio values of NP and control groups were calculated and statistically compared. Neutrophil to lymphocyte and PLR values were statistically compared in terms of NP density in the NP group.


RESULTS
Mean NLR value was 2.26 in the NP group and 1.75 in the control group with a statistically significant difference (p=0.001). Mean PLR value was 120.79 in the NP group and 109.84 in the control group with a statistically insignificant difference (p=0.073).


CONCLUSIONS
Neutrophil to lymphocyte ratio value may be used as a novel marker that is easily administered in patients with nasal polyps and obtained with low-cost tests. New studies with larger patient series are needed for the value of PLR.
Department of Otolaryngology, Ankara Numune Training and Research Hospital, 06830 Altındağ, Ankara, Turkey. doganatan@gmail.com.
Doğan
D
Atan
Kürşat Murat
KM
Özcan
Sabri
S
Köseoğlu
Aykut
A
İkincioğulları
Mehmet Ali
MA
Çetin
Serdar
S
Ensari
Hüseyin
H
Dere
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001792:Blood Platelets / Q000473:pathology*; D005260:Female; D006801:Humans; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000473:pathology*; D009504:Neutrophils / Q000473:pathology*; D010976:Platelet Count; D011237:Predictive Value of Tests; D011379:Prognosis; D012720:Severity of Illness Index; D055815:Young Adult