Synthesis and characterization of 4-aryl-4H-chromenes from H-cardanol.
We have synthesized and characterized a variety of fat-soluble, low-melting and medicinally useful 4-aryl-4H-chromenes from H-cardanol (side-chain perhydrogenated cardanol, 3-pentadecylphenol), a renewable and low-cost product from locally grown cashew nut trees (Anacardium occidentale L.). We incorporated H-cardanol into the aromatic rings of either 4H-chromene or phenol, or both. Substitution of C4SMe in N-methyl-4-(methylthio)-3-nitro-4H-chromene-2-amines with H-cardanol was regio-specific at the C6 position.
Hulluru Surya Prakash
HS
Rao
Mani
M
Kamalraj
D031021:Anacardium / Q000737:chemistry; D001578:Benzopyrans / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*
D001578:Benzopyrans; D010636:Phenols; C038590:cardanol