Photoreactivity of the linker region of two consecutive G-quadruplexes formed by human telomeric DNA.
We report the application of a photoreaction method for probing two consecutive G-quadruplexes formed by human telomeric DNA. This method can discriminate the loop structure located between two consecutive G-quadruplexes formed by eight TTAGGG repeats in K(+) and Na(+) solutions.
Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan. hs@kuchem.kyoto-u.ac.jp.
Yue
Y
Li
Hiroshi
H
Sugiyama
D004247:DNA / Q000737:chemistry* / Q000528:radiation effects*; D054856:G-Quadruplexes / Q000528:radiation effects*; D006801:Humans; D055668:Photochemical Processes; D011188:Potassium / Q000737:chemistry; D012091:Repetitive Sequences, Nucleic Acid; D012964:Sodium / Q000737:chemistry; D012996:Solutions; D016615:Telomere / Q000737:chemistry* / Q000528:radiation effects*
D012996:Solutions; D004247:DNA; D012964:Sodium; D011188:Potassium