Spontaneous intracranial haemorrhage in children with chronic immune thrombocytopenic purpura.
Spontaneous intracranial haemorrhage (ICH) is a rare complication of chronic immune thrombocytopenic purpura (ITP) in children. We report four patients with cITP who developed ICH. The latency between onset of ITP and ICH varied from 1-8 years. All our patients were profoundly thrombocytopenic (platelet count of <10 x 109/l) at the time of their intracranial bleed. The presenting features and management are discussed. All patients survived, three had complete neurological recovery while one had a minimal residual neurological deficit.
Hospital Kuala Lumpur, Paediatric Institute, Department of Paediatrics, Haematology-Oncology Unit,Jalan Pahang, 50586 Kuala Lumpur, Malaysia. zuedr@yahoo.com.
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Muda
Hospital Kuala Lumpur, Paediatric Institute, Department of Paediatrics, Haematology-Oncology Unit,Jalan Pahang, 50586 Kuala Lumpur, Malaysia.
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Ibrahim
Hospital Kuala Lumpur, Paediatric Institute, Department of Paediatrics, Haematology-Oncology Unit,Jalan Pahang, 50586 Kuala Lumpur, Malaysia.
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Abdulrahman
Hospital Kuala Lumpur, Paediatric Institute, Department of Paediatrics, Haematology-Oncology Unit,Jalan Pahang, 50586 Kuala Lumpur, Malaysia.
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Mahfuzah
Hospital Kuala Lumpur, Paediatric Institute, Department of Paediatrics, Haematology-Oncology Unit,Jalan Pahang, 50586 Kuala Lumpur, Malaysia.
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Othman
Hospital Kuala Lumpur, Paediatric Institute, Department of Paediatrics, Haematology-Oncology Unit,Jalan Pahang, 50586 Kuala Lumpur, Malaysia.
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Asohan
Hospital Kuala Lumpur, Paediatric Institute, Department of Paediatrics, Haematology-Oncology Unit,Jalan Pahang, 50586 Kuala Lumpur, Malaysia.
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Menon