Incidence and risk factors of bacterial vaginosis among pregnant women: a prospective study in Maanshan city, Anhui Province, China.
OBJECTIVE
The aim of this study was to identify the incidence and risk factors of bacterial vaginosis among pregnant women.


METHODS
Prospective data from a cohort of 668 pregnant women were used to identify potential risk factors for bacterial vaginosis during pregnancy by Cox proportional hazards regression.


RESULTS
A total of 204 incident cases of bacterial vaginosis were diagnosed in 274.8 woman-years of follow-up. The bacterial vaginosis incidence rate was 0.74 per 1 woman-year and median prevalence during follow-up was 15.6%. In the adjusted model, changing underwear nearly everyday, miscarriage history, urinary tract infection during follow-up, husbands' education level, and concurrent trichomoniasis and candidiasis remained significantly associated with bacterial vaginosis (adjusted hazard ratio and 95% confidence interval were 1.87 [1.26-2.77]; 2.96 [1.96-4.47]; 2.41 [1.05-5.49]; 0.50 [0.32-0.77]; 1.82 [1.02-3.25]; 1.88 [1.30-2.70], respectively).


CONCLUSIONS
Bacterial vaginosis during pregnancy can be affected by many factors, and some are indirectly acting factors. Further prospective studies that include a larger sample size and more information on the development of bacterial vaginosis are needed.
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Xiu-De
XD
Li
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Fei
F
Tong
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Xiu-Jun
XJ
Zhang
Department of Obstetrics and Gynaecology, Maternal and Child Health Care Hospital of Maanshan, Maanshan, Anhui, People's Republic of China.
Wei-Jun
WJ
Pan
Department of Obstetrics and Gynaecology, Maternal and Child Health Care Hospital of Maanshan, Maanshan, Anhui, People's Republic of China.
Mao-Lin
ML
Chen
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Cheng-Cheng
CC
Wang
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Xiang
X
Li
Anhui No. 2 Province People's Hospital, Hefei, Anhui, People's Republic of China.
Guo-Peng
GP
Gao
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Liang
L
Sun
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Ye-Huan
YH
Sun
D000328:Adult; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012307:Risk Factors; D016585:Vaginosis, Bacterial / Q000453:epidemiology* / Q000209:etiology
China; bacterial vaginosis; incidence; pregnant women; risk factors