Diabetes mellitus prevalence in tuberculosis patients and the background population in Guinea-Bissau: a disease burden study from the capital Bissau.
BACKGROUND
Data regarding the association between diabetes mellitus (DM) and tuberculosis (TB) in Africa are scare. We did a DM screening survey among TB patients and non-TB controls in Guinea-Bissau.


METHODS
The study was conducted at the Bandim Health Project (BHP) in the capital Bissau. From July 2010 to July 2011, newly diagnosed TB cases were identified through a TB notification system. Concurrently, non-TB controls were selected randomly from the BHP's demographic surveillance database and visited at home. Participants were tested using fasting blood glucose (FBG) measurements. DM was diagnosed as FBG ≥ 7 mmol/l. Our survey was linked to the patient database at the only existing Diabetes Clinic in Bissau.


RESULTS
TB patients (n=110) were older than the controls (n=572) (35 vs 31 years; p=0.02), more often male (55% vs 37%; p<0.001) and had a lower body mass index (18.7 vs 24.2 kg/m(2); p<0.001). The prevalence of DM was 2.8% (3/107) for TB patients and 2.1% (11/531) for controls (p=0.64). Excluding two controls already receiving anti-diabetic treatment, the prevalence of DM was 2.8% (3/107) vs 1.7% (9/529) (p=0.44).


CONCLUSIONS
The prevalence of DM was low, also among TB patients. No association between DM and TB was found.
Bandim Health Project, Apartado 861, 1004 Bissau Codex, Guinea-Bissau Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark thornylinda@gmail.com.
Thorny L
TL
Haraldsdottir
Bandim Health Project, Apartado 861, 1004 Bissau Codex, Guinea-Bissau Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
Frauke
F
Rudolf
Bandim Health Project, Apartado 861, 1004 Bissau Codex, Guinea-Bissau Research Center for Vitamins and Vaccines (CVIVA), Statens Serum Institute, Copenhagen, Denmark Department of Endocrinology, Odense University Hospital, Odense, Denmark.
Morten
M
Bjerregaard-Andersen
Bandim Health Project, Apartado 861, 1004 Bissau Codex, Guinea-Bissau The National Diabetes Association (ANDD), Bissau, Guinea-Bissau.
Luis Carlos
LC
Joaquím
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Kirstine
K
Stochholm
Bandim Health Project, Apartado 861, 1004 Bissau Codex, Guinea-Bissau.
Victor F
VF
Gomes
Department of Endocrinology, Odense University Hospital, Odense, Denmark.
Henning
H
Beck-Nielsen
Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
Lars
L
Ostergaard
Bandim Health Project, Apartado 861, 1004 Bissau Codex, Guinea-Bissau Research Center for Vitamins and Vaccines (CVIVA), Statens Serum Institute, Copenhagen, Denmark.
Peter
P
Aaby
Bandim Health Project, Apartado 861, 1004 Bissau Codex, Guinea-Bissau Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark GloHAU, Center for Global Health, Department of Public Health, Aarhus University, Denmark.
Christian
C
Wejse
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D003920:Diabetes Mellitus / Q000097:blood / Q000453:epidemiology*; D005215:Fasting; D005260:Female; D006169:Guinea-Bissau / Q000453:epidemiology; D006801:Humans; D008297:Male; D008403:Mass Screening; D015995:Prevalence; D014376:Tuberculosis / Q000097:blood / Q000453:epidemiology*; D014505:Urban Population / Q000706:statistics & numerical data*
D001786:Blood Glucose
Association; Diabetes mellitus; Disease burden study; Sub-Saharan Africa; Tuberculosis