Therapeutic outcome after resection of pulmonary metastases from oral and/or head and neck cancers: complete republication of the article published in Jpn J Chest Surg.
OBJECTIVE
Thus far, very few studies have assessed the efficacy and outcome of resection of pulmonary metastases originating from primary oral cancer and/or head and neck cancer.


METHODS
We retrospectively reviewed 13 cases that had metastases from primary oral cancers and/or head and neck cancers, and had undergone metastasectomy in our hospital from January 2000 through March 2011.


RESULTS
Twelve patients were male and one was female. The median disease-free interval from the time of treatment of their primary cancer was 12 (range 1-73) months. Eleven cases underwent partial resection, one underwent segmentectomy, and one underwent lobectomy. The overall 5-year survival rate after last pulmonary metastasectomy was 45.7 %, and the median survival time was 23 months. Factors predicting a poor prognosis according to univariate analysis were a disease-free interval of <12 months and a diagnosis of stage IV primary cancer, but multivariate analysis revealed no significant prognostic factors.


CONCLUSIONS
Pulmonary metastasectomy would give a chance for long-term survival in patients with oral and/or head and neck cancers.
Department of Surgery, Yokohama City University, Yokohama, Japan, adachi-fam@m2.gyao.ne.jp.
Hiroyuki
H
Adachi
Taketsugu
T
Yamamoto
Shizu
S
Saito
Hiroko
H
Nemoto
Yasushi
Y
Rino
Munetaka
M
Masuda
D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000601:surgery*; D005260:Female; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D008297:Male; D059146:Metastasectomy / Q000379:methods / Q000401:mortality; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000601:surgery; D015999:Multivariate Analysis; D011013:Pneumonectomy / Q000379:methods / Q000401:mortality; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome