Intraperitoneal oxidative stress as an oncolytic immunomodulator?
Intraperitoneal oxidative stress effectively converts the immune response against the papillomavirus-associated rabbit VX2 carcinoma from tumor permissive to tumoricidal and leads to a sustainable oncolytic immune response that can be adoptively transferred.
Department of Molecular Neuroscience, Institute of Anatomy and Cell Biology, Philipps University , Marburg, Germany.
Michael
M
Bette
Department of Otorhinolaryngology; Head and Neck Surgery, University Hospital Giessen and Marburg; Campus Marburg , Marburg, Germany.
Robert
R
Mandic
VX2; cancer therapy; head and neck cancer; oxidative stress; papillomavirus; tumor animal model