Characterization of the Punta Toro species complex (genus Phlebovirus, family Bunyaviridae).
Punta Toro virus (PTV), a member of the PTV complex, is a relatively common causative agent of febrile illness in Panama that is often misdiagnosed as 'dengue' or 'influenza'. Currently, only two named members make up this species complex, PTV and Buenaventura virus (BUEV). Genomic and antigenic characterization of 17 members of the PTV complex, nine of which were isolated from human acute febrile illness cases, reveals that this species complex is composed of six distant viruses. We propose to add four additional new viruses, designated Leticia virus, Cocle virus, Campana virus and Capira virus.
Center for Genome Sciences, United States Army Medical Research Institute for Infectious Diseases, Frederick, MD, USA.
Gustavo
G
Palacios
Center for Genome Sciences, United States Army Medical Research Institute for Infectious Diseases, Frederick, MD, USA.
Michael R
MR
Wiley
Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
Amelia P A
APA
Travassos da Rosa
Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
Hilda
H
Guzman
Department of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama.|Department of Microbiology, University of Panama, Panama City, Panama.
Evelia
E
Quiroz
School of Medicine, New York University, New York, NY, USA.
Nazir
N
Savji
Department of Virology and Biotechnology Research, Gorgas Memorial Institute of Health Studies, Panama City, Panama.|School of Medicine, Columbus University, Panama City, Panama.
Jean-Paul
JP
Carrera
Center for Infection and Immunity, Columbia University, New York, NY, USA.
Ana Valeria
AV
Bussetti
Center for Genome Sciences, United States Army Medical Research Institute for Infectious Diseases, Frederick, MD, USA.
Jason T
JT
Ladner
Center for Infection and Immunity, Columbia University, New York, NY, USA.
W
W
Ian Lipkin
Center for Biodefense and Emerging Infectious Diseases, Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
Robert B
RB
Tesh
D000818:Animals; D000914:Antibodies, Viral; D002044:Bunyaviridae Infections / Q000276:immunology / Q000821:virology*; D003429:Cross Reactions; D005334:Fever / Q000276:immunology / Q000821:virology*; D006801:Humans; D007303:Insect Vectors / Q000821:virology; D008969:Molecular Sequence Data; D010176:Panama; D016856:Phlebovirus / Q000145:classification / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D010802:Phylogeny; D011576:Psychodidae / Q000821:virology
D000914:Antibodies, Viral