Dipterostilbenosides A and B, oligostilbene glycosides from Dipterocarpus tuberculatus.
From the chemical investigation of the methanolic extract of the roots of the Thai dipterocarp, Dipterocarpus tuberculatus, two new oligostilbene glycosides, dipterostilbenes A (1) and B (2), were isolated together with four known stilbenes. Their structures and relative configurations were determined on the basis of spectroscopic data. From an evaluation of cytotoxic activity against KB and HeLa cell lines, α-viniferin (5) and (-)-hopeaphenol (6) showed potent activity, but less than that of doxorubicin.
Serm
S
Surapinit
Jonkolnee
J
Jong-aramruang
Pongpun
P
Siripong
Suttira
S
Khumkratok
Santi
S
Tip-pyang
D002460:Cell Line; D049109:Cell Proliferation / Q000187:drug effects; D006027:Glycosides / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D013267:Stilbenes / Q000737:chemistry* / Q000494:pharmacology
D006027:Glycosides; D010936:Plant Extracts; D013267:Stilbenes