Association between vasoactive-inotropic score and mortality in pediatric septic shock.
OBJECTIVE
To assess the association between Vasoactive Inotrope Score (vis) and mortality in children with fluid-refractory septic shock.


METHODS
A retrospective chart review of 71 children (age 1 mo-16y) admitted with fluid-refractory septic shock in pediatric intensive care unit during a two year period was done. We divided our cohort into two groups viz High vasoactive inotrope score (Group-H) and Low-vasoactive inotrope score (Group-L) based on a cut-off value of 20.


RESULTS
73% of the children were in Group-L. The mortality rate was 44% and 100% in Group L and Group H, respectively.


CONCLUSIONS
High inotropic score in children with septic shock is associated with high mortality rate.
Departments of Pediatrics and Child Health, and *Emergency Medicine, Aga Khan University Hospital, Karachi, Pakistan. Correspondence to: Dr Anwarul Haque, Associate Professor, Department of Pediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan. anwar.haq@aku.edu.
A
A
Haque
N R
NR
Siddiqui
O
O
Munir
S
S
Saleem
A
A
Mian
D002648:Child; D002675:Child, Preschool; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007223:Infant; D015278:Intensive Care Units, Pediatric; D007902:Length of Stay; D008297:Male; D010154:Pakistan / Q000453:epidemiology; D012189:Retrospective Studies; D012720:Severity of Illness Index; D012772:Shock, Septic / Q000453:epidemiology / Q000401:mortality* / Q000503:physiopathology* / Q000628:therapy; D016896:Treatment Outcome