Sedating drugs and breastfeeding.
OBJECTIVE
If a mother takes a sedating drug during breastfeeding, will it cause central nervous system (CNS) depression in her breastfed baby?


CONCLUSIONS
In some cases (eg, with the use of codeine or oxycodone) sedating drugs will likely cause CNS depression in breastfed infants and in other cases (eg, with the use of benzodiazepines) they will likely not. Mothers using sedating drugs should monitor their breastfed infants for signs of CNS depression (eg, drowsiness; difficulty breathing, feeding, or latching; or cyanosis), paradoxical effects (eg, unusual excitement,irritability), or inadequate weight gain.
Cheuk Kiu
CK
Chow
Gideon
G
Koren
D001569:Benzodiazepines / Q000009:adverse effects*; D001942:Breast Feeding; D002493:Central Nervous System Diseases / Q000139:chemically induced*; D003061:Codeine / Q000009:adverse effects; D000075202:Contraindications; D005260:Female; D006633:Histamine Antagonists / Q000009:adverse effects; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D007223:Infant; D008895:Milk, Human / Q000378:metabolism; D009035:Mothers; D009294:Narcotics / Q000009:adverse effects
D006633:Histamine Antagonists; D006993:Hypnotics and Sedatives; D009294:Narcotics; D001569:Benzodiazepines; D003061:Codeine