Imaging of cerebrovascular disorders: precision medicine and the collaterome.
Imaging of stroke and neurovascular disorders has profoundly enhanced clinical practice and related research during the last 40 years since the introduction of computed tomography (CT) and magnetic resonance imaging (MRI) enabled mapping of the brain. We highlight recent advances in neurovascular imaging. We describe how the convergence of readily available data and new clinical trial paradigms will recast our methods for studying the neurovascular patient. The application of a precision medicine approach to the collaterome, a comprehensive synthesis of neurovascular pathophysiology, will entail novel methods for clinical trial randomization, collection of routine and clinical trial imaging results, data archiving, and analysis.
Neurovascular Imaging Research Core and the University of California, Los Angeles Stroke Center, Los Angeles, California.
David S
DS
Liebeskind
Baystate Medical Center, Springfield, Massachusetts.
Edward
E
Feldmann
D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002986:Clinical Trials as Topic / Q000379:methods; D003097:Collateral Circulation / Q000502:physiology*; D003952:Diagnostic Imaging / Q000379:methods / Q000639:trends; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000639:trends; D057285:Precision Medicine / Q000379:methods* / Q000639:trends; D014057:Tomography, X-Ray Computed / Q000379:methods* / Q000639:trends
collaterals; data science; imaging; stroke