A rapid, fully automated and highly sensitive ADAMTS13 gold particle immunoassay using a routine biochemistry analyser.
Division of Diagnostic R&D, Alfresa Pharma Corporation, Osaka, Japan. seiji-katoh@alfresa-pharma.co.jp.
Seiji
S
Kato
Division of Diagnostic R&D, Alfresa Pharma Corporation, Osaka, Japan.
Mutsumi
M
Tanaka
Department of Blood Transfusion Medicine, Nara Medical University, Nara, Japan.
Ayami
A
Isonishi
Department of Blood Transfusion Medicine, Nara Medical University, Nara, Japan.
Masanori
M
Matsumoto
Research Division, Japan Clinical Laboratories, Inc., Kyoto, Japan.
Tomohiro
T
Samori
Department of Blood Transfusion Medicine, Nara Medical University, Nara, Japan.
Yoshihiro
Y
Fujimura
D051722:ADAM Proteins / Q000097:blood*; D000071120:ADAMTS13 Protein; D000372:Agglutination Tests / Q000295:instrumentation / Q000379:methods*; D000911:Antibodies, Monoclonal / Q000276:immunology; D057134:Antibodies, Neutralizing / Q000276:immunology; D000937:Antigen-Antibody Reactions; D001331:Automation; D002384:Catalysis; D002863:Chromogenic Compounds / Q000032:analysis; D004796:Clinical Enzyme Tests / Q000295:instrumentation / Q000379:methods*; D004797:Enzyme-Linked Immunosorbent Assay; D005982:Glutathione Transferase / Q000032:analysis / Q000235:genetics / Q000276:immunology; D017979:Gold Colloid; D006801:Humans; D009391:Nephelometry and Turbidimetry; D011993:Recombinant Fusion Proteins / Q000032:analysis / Q000276:immunology; D012680:Sensitivity and Specificity; D057049:Thrombotic Microangiopathies / Q000201:enzymology*; D014841:von Willebrand Factor / Q000032:analysis / Q000235:genetics
D000911:Antibodies, Monoclonal; D057134:Antibodies, Neutralizing; D002863:Chromogenic Compounds; D017979:Gold Colloid; D011993:Recombinant Fusion Proteins; D014841:von Willebrand Factor; D005982:Glutathione Transferase; D051722:ADAM Proteins; D000071120:ADAMTS13 Protein; C099604:ADAMTS13 protein, human
ADAMTS13; assay; thrombotic microangiopathy; thrombotic thrombocytopenic purpura