Injectable and mechanically robust 4-arm PPO-PEO/graphene oxide composite hydrogels for biomedical applications.
Graphene-based nanomaterials with different oxidation degrees were incorporated into Tetronic-tyramine (Tet-TA) hydrogels via enzymatic cross-linking. The molecular oxidation of graphene in combination with amphiphilic Tet-TA significantly improved the water dispersibility of graphene oxide (GO), resulting in a significant reinforcement of Tet-TA/GO composite hydrogels that can be used as an injectable biomaterial platform.
Department of Molecular Science and Technology, Ajou University, San 5, Woncheon, Yeongtong, Suwon 443-749, Republic of Korea. kdp@ajou.ac.kr.
Yunki
Y
Lee
Jin Woo
JW
Bae
Thai Thanh
TT
Hoang Thi
Kyung Min
KM
Park
Ki Dong
KD
Park
D016475:3T3 Cells; D000818:Animals; D001672:Biocompatible Materials / Q000008:administration & dosage / Q000138:chemical synthesis / Q000737:chemistry*; D035843:Biomedical Research; D006108:Graphite / Q000737:chemistry*; D020100:Hydrogels / Q000008:administration & dosage* / Q000138:chemical synthesis / Q000737:chemistry*; D007267:Injections; D051379:Mice; D010087:Oxides / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D011409:Propylene Glycols / Q000737:chemistry*; D014439:Tyramine / Q000737:chemistry
D001672:Biocompatible Materials; D020100:Hydrogels; D010087:Oxides; D011108:Polymers; D011409:Propylene Glycols; C012504:polypropylene glycol; D011092:Polyethylene Glycols; D006108:Graphite; D014439:Tyramine