Rational design of new ligands for nicotinic receptors on the basis of α-conotoxin PnIA.
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia, shak_ever@yahoo.com.
I E
IE
Kasheverov
D S
DS
Kudryavtsev
I A
IA
Ivanov
M N
MN
Zhmak
A O
AO
Chugunov
V M
VM
Tabakmakher
E A
EA
Zelepuga
R G
RG
Efremov
V I
VI
Tsetlin
D000109:Acetylcholine / Q000494:pharmacology; D000465:Algorithms; D000595:Amino Acid Sequence; D000818:Animals; D001048:Aplysia; D020916:Conotoxins / Q000737:chemistry* / Q000235:genetics; D004305:Dose-Response Relationship, Drug; D015195:Drug Design; D006801:Humans; D008024:Ligands; D008195:Lymnaea; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D008958:Models, Molecular; D008969:Molecular Sequence Data; D018722:Nicotinic Agonists / Q000494:pharmacology; D018733:Nicotinic Antagonists / Q000737:chemistry* / Q000494:pharmacology; D009865:Oocytes; D014982:Xenopus laevis; D064569:alpha7 Nicotinic Acetylcholine Receptor / Q000819:agonists / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism
D020916:Conotoxins; D008024:Ligands; D018722:Nicotinic Agonists; D018733:Nicotinic Antagonists; C089038:alpha-conotoxin PnIA; D064569:alpha7 Nicotinic Acetylcholine Receptor; D000109:Acetylcholine