[Metastatic screening before adjuvant chemotherapy in breast cancer].
BACKGROUND
Systematic metastasis staging in early breast cancer is no longer recommended. However, it is still performed before adjuvant chemotherapy.


METHODS
We assessed metastasis screening of asymptomatic women with a local breast cancer without lymph node involvement when adjuvant chemotherapy was indicated. The screening result was classified in 3 groups: "non-metastatic", "metastatic" and "suspect". For suspect screening, we analyzed the checking period and the consequences on cares.


RESULTS
Out of 1545 patients with possible indication of chemotherapy, 690 indications of chemotherapy were validated by multidisciplinary meeting. Six hundred and thirty-nine metastasis screening were done. Five hundred and fifty-five screenings (86.9 %) were "non-metastatic", 3 screenings (0.5 %) were "metastatic" and 81 screenings (12.7 %) were "suspect". Out of this 81 suspect screening, only 47 screening have been checked, using 61 further investigations. No breast cancer metastasis was finally identified.


CONCLUSIONS
Low rate of metastasis suggest reassessing metastasis screening before adjuvant chemotherapy for patients without lymph node involvement.
Centre Léon-Bérard, département de chirurgie cancérologique-sein, 28, rue Laennec, 69373 Lyon cedex 08, France. Electronic address: thonnoncyrielle@yahoo.fr.
Cyrielle
C
Thonnon
Centre Léon-Bérard, département de chirurgie cancérologique-sein, 28, rue Laennec, 69373 Lyon cedex 08, France.
Christelle
C
Faure
Centre Léon-Bérard, département de chirurgie cancérologique-sein, 28, rue Laennec, 69373 Lyon cedex 08, France.
Nicolas
N
Chopin
Centre Léon-Bérard, département de chirurgie cancérologique-sein, 28, rue Laennec, 69373 Lyon cedex 08, France.
Frédéric
F
Beurrier
Centre Léon-Bérard, département de chirurgie cancérologique-sein, 28, rue Laennec, 69373 Lyon cedex 08, France.
Christophe
C
Ho Quoc
Centre Léon-Bérard, département d'oncologie médicale, 28, rue Laennec, 69373 Lyon cedex 08, France.
Olivier
O
Tredan
Centre Léon-Bérard, département de chirurgie cancérologique-sein, 28, rue Laennec, 69373 Lyon cedex 08, France.
Nicolas
N
Carrabin
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D008198:Lymph Nodes; D008207:Lymphatic Metastasis; D008875:Middle Aged; D012189:Retrospective Studies
Bibliographic database; Bibliometrics; Bilan d’extension; Breast cancer; Cancer du sein; Chimiothérapie; Faux positif; France; Medical research; Métastase; Non-envahissement ganglionnaire