Performance of three multipurpose disinfecting solutions with a silicone hydrogel contact lens.
OBJECTIVE
To evaluate the clinical performance of a silicone hydrogel (Si-Hy) soft contact lens (CL) in combination with three different multipurpose disinfecting solutions (MPDSs).


METHODS
This was a prospective, randomized, single-masked, crossover, and comparative study in which 31 habitual soft CL wearers were randomly assigned to one of the three MPDSs (Synergi, COMPLETE RevitaLens, and OPTI-FREE PureMoist) for 1 month with a 1-week wash-out period between each exposure. All subjects were successfully refitted with a Si-Hy CL (Biofinity). Subjects were then scheduled for follow-up visits after 1 month of lens wear, being evaluated at 2 and 8 hours after lens insertion. Visual Analogue Scales (VAS) were used to gauge comfort rating.


RESULTS
The tarsal conjunctiva showed a significantly different degree of lid redness between the MPDSs at the 2-hour visit (P < 0.05, Kruskal-Wallis test), being lower for COMPLETE RevitaLens compared to the other two MPDSs (Mann-Whitney U test). Furthermore, a significantly different degree of lid roughness at the 8-hour visit was seen (P < 0.05, Kruskal-Wallis test), being higher for Synergi (Mann-Whitney U test). The subjective comfort was similar with the three MPDSs.


CONCLUSIONS
Tarsal conjunctival response should be also considered in the context of the clinical performance of MPDs at the ocular surface.
Clinical & Experimental Optometry Research Lab, Center of Physics (Optometry), University of Minho, 4710-057 Braga, Portugal ; Ocular Surface and Contact Lenses Research Group, University of Santiago de Compostela, 15782 A Coruña, Spain.
Nery
N
García-Porta
Clinical & Experimental Optometry Research Lab, Center of Physics (Optometry), University of Minho, 4710-057 Braga, Portugal.
Laura
L
Rico-del-Viejo
Clinical & Experimental Optometry Research Lab, Center of Physics (Optometry), University of Minho, 4710-057 Braga, Portugal.
Helena
H
Ferreira-Neves
Clinical & Experimental Optometry Research Lab, Center of Physics (Optometry), University of Minho, 4710-057 Braga, Portugal.
Sofia C
SC
Peixoto-de-Matos
Clinical & Experimental Optometry Research Lab, Center of Physics (Optometry), University of Minho, 4710-057 Braga, Portugal.
Antonio
A
Queirós
Clinical & Experimental Optometry Research Lab, Center of Physics (Optometry), University of Minho, 4710-057 Braga, Portugal.
José M
JM
González-Méijome
D000328:Adult; D018639:Contact Lens Solutions / Q000737:chemistry*; D003263:Contact Lenses, Hydrophilic; D003315:Cornea / Q000473:pathology*; D018592:Cross-Over Studies; D004202:Disinfectants / Q000737:chemistry*; D004203:Disinfection; D005260:Female; D006801:Humans; D020100:Hydrogels / Q000737:chemistry*; D008297:Male; D011446:Prospective Studies; D012828:Silicones / Q000737:chemistry*; D011795:Surveys and Questionnaires; D064232:Visual Analog Scale; D055815:Young Adult
D018639:Contact Lens Solutions; D004202:Disinfectants; D020100:Hydrogels; D012828:Silicones