[Does nodal irradiation (clavicular and internal mammary chains) increase the toxicity of adjuvant breast radiotherapy?].
Treatment volume is a major risk factor of radiation-induced toxicity. As nodal irradiation increases treatment volume, radiation toxicity should be greater. Nevertheless, scientific randomised data do not support this fact. However, a radiation-induced toxicity is possible outside tangential fields in the nodal volumes not related to breast-only treatment. Treatment should not be adapted only to the disease but personalized to the individual risk of toxicity for each patient.
Pôle d'oncologie radiothérapie, ICM-Val d'Aurelle, rue de la Croix-Verte, 34298 Montpellier cedex 5, France. Electronic address: Olivier.riou@icm.unicancer.fr.
O
O
Riou
Pôle d'oncologie radiothérapie, ICM-Val d'Aurelle, rue de la Croix-Verte, 34298 Montpellier cedex 5, France.
C
C
Bourgier
Pôle d'oncologie radiothérapie, ICM-Val d'Aurelle, rue de la Croix-Verte, 34298 Montpellier cedex 5, France.
P
P
Fenoglietto
Pôle d'oncologie radiothérapie, ICM-Val d'Aurelle, rue de la Croix-Verte, 34298 Montpellier cedex 5, France.
D
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Azria
D001940:Breast; D001943:Breast Neoplasms / Q000532:radiotherapy*; D002968:Clavicle; D005260:Female; D006801:Humans; D015182:Lymphatic Irradiation; D011832:Radiation Injuries / Q000209:etiology*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects*
Breast cancer; Cancer du sein; Chaîne claviculaire; Chaîne mammaire interne; Clavicular chain; Internal mammary chain; Irradiation ganglionnaire; Nodal irradiation; Radio-induced toxicity; Radiotherapy; Radiothérapie; Toxicité radio-induite