IgG4-Related Systemic Disease Can Be Easily Mistaken as a Uroepithelial Tumor.
Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic syndrome characterized by elevated serum IgG4 concentrations and tumefaction or tissue infiltration by IgG4-positive plasma cells. We experienced a case of IgG4-RD involving multiple organs in a 64-year-old female who was referred for a suspected uroepithelial tumor. A mass biopsy confirmed dense lymphoplasmacytic infiltration with an increased number of IgG4-positive plasma cells. We discuss this case and review the literature to bring IgG4-RD to the attention to clinicians because it responds dramatically well to steroid therapy and should be kept in mind as a differential diagnosis to avoid unnecessary surgery.
Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Song Yi
SY
Han
Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Seung Ik
SI
Lee
Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Yeon Hee
YH
Lee
Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Ae Jin
AJ
Kim
Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Hye Jin
HJ
Lim
Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea. ; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Han
H
Ro
Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea. ; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Jae Hyun
JH
Chang
Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea. ; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Hyun Hee
HH
Lee
Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea. ; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Wookyung
W
Chung
Division of Nephrology, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea. ; Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.
Ji Yong
JY
Jung
Immunoglobulin G; Kidney; Sclerosis