Benign chondroblastoma on fine-needle aspiration smears: A seven-case experience and review of the literature.
We report seven cases of chondroblastoma (CB) of bone, diagnosed by Fine-Needle Aspiration Cytology (FNAC), and confirmed by histomorphological examination. The concurrence of some cytomorphologic findings - mononucleated cells, multinucleated cells, and intercellular chondroid substance - unequivocally suggested the cytological diagnosis of CB. We also reviewed the literature on this topic in order to discuss morphological criteria and the importance of needle size. The differential diagnosis between CB, Giant Cell Tumor of Bone, and Eosinophilic Granuloma is further discussed.
Cytopathology Service, Department of Public Health, Azienda Ospedaliera Universitaria "Federico II", 80131, Napoli, Italy.
Immacolata
I
Cozzolino
Department of Medicine and Surgery, University of Salerno, Baronissi, Italy.
Pio
P
Zeppa
Cytopathology Service, Department of Public Health, Azienda Ospedaliera Universitaria "Federico II", 80131, Napoli, Italy.
Assunta
A
Zabatta
Departments of Advanced Biomedical Sciences, Azienda Ospedaliera Universitaria "Federico II", 80131, Napoli, Italy.
Francesco
F
Merolla
Cytopathology Service, Department of Public Health, Azienda Ospedaliera Universitaria "Federico II", 80131, Napoli, Italy.
Antonio
A
Vetrani
Orthopedic Service, Department of Public Health, Azienda Ospedaliera Universitaria "Federico II", 80131, Napoli, Italy.
Francesco
F
Sadile
D000293:Adolescent; D000328:Adult; D044963:Biopsy, Fine-Needle; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology; D001842:Bone and Bones / Q000473:pathology; D002648:Child; D002804:Chondroblastoma / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D005870:Giant Cell Tumors / Q000175:diagnosis / Q000473:pathology; D015726:Giant Cells / Q000166:cytology*; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D055815:Young Adult
bone cytology; bone tumors; chondroblastoma; fine-needle aspiration cytology