Independent factors affecting recovery time after sedation in patients with intellectual disabilities.
Purpose : The purpose of this study was to identify independent factors associated with prolonged recovery time after intravenous sedation for dental treatment in patients with intellectual disabilities. Methods : This study was designed as a prospective cohort study. Participants were patients with intellectual disabilities, for whom sedation for dental treatment was planned in Okayama University Hospital. The outcome variable was recovery time. The predictor variables were patient background, antiepileptic and psychotropic drugs, and anesthesia-related variables. Factors affecting the outcome were examined with multiple regression analysis. Results : We enrolled 260 cases in this study. Oral midazolam was a strong independent determinant in prolonged recovery time. Teeth extraction, short treatment time and lower body mass index were significant independent predictors of prolonged recovery time. Conclusion : Oral midazolam is a clear independent determinant of prolonged recovery time after sedation, while psychotropic drugs and antiepileptic drugs were not independent determinants in this study.
Department of Dental Anesthesiology, Okayama University Hospital. Okayama, Japan.
Shigeru
S
Maeda
Department of Dental Anesthesiology and Special Care Dentistry, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Yumiko
Y
Tomayasu
Department of Dental Anesthesiology, Okayama University Hospital. Okayama, Japan.
Hitoshi
H
Higuchi
Department of Dental Anesthesiology, Okayama University Hospital. Okayama, Japan.
Minako
M
Ishii-Maruhama
Department of Dental Anesthesiology, Okayama University Hospital. Okayama, Japan.
Ayaka
A
Yamane
Department of Dental Anesthesiology, Okayama University Hospital. Okayama, Japan.
Akiko
A
Yabuki
Department of Dental Anesthesiology and Special Care Dentistry, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Yuka
Y
Honda
Special Needs Dentistry, Okayama University Hospital, Okayama, Japan.
Masahiko
M
Egusa
Department of Dental Anesthesiology and Special Care Dentistry, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Takuya
T
Miyawaki
Anesthesia recovery period; intellectual disability; midazolam; propofol