Theories of aging: an ever-evolving field.
Senescence has been the focus of research for many centuries. Despite significant progress in extending average human life expectancy, the process of aging remains largely elusive and, unfortunately, inevitable. In this review, we attempted to summarize the current theories of aging and the approaches to understanding it.
Belozersky Institute of Physico-Chemical Biology, Moscow State University, Leninskie Gory 1, bld. 40, 119992, Moscow, Russia ; Chemistry Department, Moscow State University, Leninskie Gory, 1, bld. 3, 119992, Moscow, Russia.
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Sergiev
Belozersky Institute of Physico-Chemical Biology, Moscow State University, Leninskie Gory 1, bld. 40, 119992, Moscow, Russia ; Chemistry Department, Moscow State University, Leninskie Gory, 1, bld. 3, 119992, Moscow, Russia.
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Dontsova
Belozersky Institute of Physico-Chemical Biology, Moscow State University, Leninskie Gory 1, bld. 40, 119992, Moscow, Russia.
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Berezkin
accumulation of damage; advanced glycation end-product; aging; life expectancy; reactive oxygen species; telomerase