Rapid and noncontact photoacoustic tomography imaging system using an interferometer with high-speed phase modulation technique.
We designed, fabricated, and tested a rapid and noncontact photoacoustic tomography (PAT) imaging system using a low-coherence interferometer with high-speed phase modulation technique. Such a rapid and noncontact probing system can greatly decrease the time of imaging. The proposed PAT imaging system is experimentally verified by capturing images of a simulated tissue sample and the blood vessels within the ear flap of a mouse (pinna) in vivo. The axial and lateral resolutions of the system are evaluated at 45 and ∼15 μm, respectively. The imaging depth of the system is 1 mm in a special phantom. Our results show that the proposed system opens a promising way to realize noncontact, real-time PAT.
School of Physics and Telecom Engineering, South China Normal University, Guangzhou 510006, China.
Jun
J
Liu
School of Physics and Telecom Engineering, South China Normal University, Guangzhou 510006, China.
Zhilie
Z
Tang
School of Physics and Telecom Engineering, South China Normal University, Guangzhou 510006, China.
Yongbo
Y
Wu
School of Control Engineering, Northeastern University at Qinhuangdao, Qinhuangdao 066004, China.
Yi
Y
Wang
D000818:Animals; D004423:Ear; D007368:Interferometry / Q000295:instrumentation*; D051379:Mice; D061088:Photoacoustic Techniques / Q000295:instrumentation*; D013997:Time Factors; D014054:Tomography / Q000295:instrumentation*