Is ciliary muscle affected in migraine patients with aura and without aura?
BACKGROUND
The aim of this study was to compare spherical equivalents (SE) and spherical equivalents with cycloplegic (CSE) values of migraine patients with and without visual aura, with those patients without migraine complaints.


METHODS
We included patients over the age of 18 years, who had 20/20 uncorrected vision, and who did not have ocular pathology in their examination. The patients were divided into 3 groups: Group 1: 86 eyes of 43 migraine patients without aura, Group 2: 38 eyes of 19 migraine patients with aura, and Group 3: 60 eyes of 30 patients without migraine. Spherical equivalents and spherical equivalents with cycloplegic from the auto-refractometrical values of the patients were compared.


RESULTS
The mean age of the migraine and control patients was 34.2±8.3 and 33.6±10.8 years, respectively. Forty-three (69%) of 62 migraine patients had migraine without aura and 19 (31%) had migraine with aura. The right and left eyes of the patients were evaluated together and a significant correlation was found between the groups. To evaluate the impact of cycloplegia in patients, SE and CSE values were obtained and differences between these values were evaluated. It was found that the change in Group 2 patients was significantly lower than the change in Group 3 patients (p=0.024).


CONCLUSIONS
We found that the cycloplegic spherical equivalents values of our patients with aura were lower than control patients. We need further studies to reveal whether migraine with aura is the trigger or the result of those attacks.
Department of Ophthalmology, Uludag University, School of Medicine, Bursa, Turkey.
Sertaç Argun
SA
Kıvanç
Department of Ophthalmology, Kastamonu Münif İslamoğlu State Hospital, Kastamonu, Turkey.
Mahmut Oğuz
MO
Ulusoy
Department of Ophthalmology, Uludag University, School of Medicine, Bursa, Turkey.
Berna
B
Akova-Budak
Department of Ophthalmology, Erzurum Region Training and Research Hospital, Erzurum, Turkey.
Osman Okan
OO
Olcaysu
Department of Neurology, Bezmialem Vakıf University, Medical Faculty, İstanbul, Turkey.
Muhammed Emin
ME
Özcan
D000065:Accommodation, Ocular / Q000187:drug effects / Q000502:physiology*; D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000503:physiopathology*; D020325:Migraine with Aura / Q000503:physiopathology*; D009184:Mydriatics / Q000494:pharmacology; D011446:Prospective Studies; D012031:Refractometry
D009184:Mydriatics