Microwave-assisted preparation of N-doped carbon dots as a biosensor for electrochemical dopamine detection.
A new N-doped carbon dots (NCDs) could be prepared by using the microwave-assisted technique within 10 min without the need for any solvent or catalyst. The NCDs exhibited a highly sensitive electrochemical response toward dopamine (DA) in Phosphate Buffered Saline (PBS) (pH=6.5). The detection limit of DA was calculated by differential pulse voltammetry (DPV) as low as 1.2×10(-9) mol/L with a linear dynamic range of 5.0×10(-8) to 8.0×10(-6) mol/L. These results suggested that this new NCDs could be effectively used for the direct and rapid detection of trace levels of DA in human serum and urine samples.
Key Lab of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China; School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China.
Yuliang
Y
Jiang
School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210097, China.
Bingxiang
B
Wang
Key Lab of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
Fandian
F
Meng
Key Lab of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China. Electronic address: yxcheng@nju.edu.cn.
Yixiang
Y
Cheng
Key Lab of Mesoscopic Chemistry of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China. Electronic address: cjzhu@nju.edu.cn.
Chengjian
C
Zhu
D015374:Biosensing Techniques / Q000379:methods*; D002021:Buffers; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D004298:Dopamine / Q000097:blood / Q000652:urine; D055664:Electrochemical Techniques; D004566:Electrodes; D006801:Humans; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D008872:Microwaves; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D012996:Solutions
D002021:Buffers; D012996:Solutions; D002244:Carbon; D004298:Dopamine
Differential pulse voltammetry; Electrochemical detection; Microwave-assisted technique; N-doped carbon dots