Endoscopic laryngo-pharyngeal surgery for superficial laryngo-pharyngeal cancer.
OBJECTIVE
Narrow band imaging (NBI) combined with magnifying endoscopy enables us to detect superficial laryngo-pharyngeal cancers, which are difficult to detect by standard endoscopy. Endoscopic laryngo-pharyngeal surgery (ELPS) is a technique developed to treat such lesions and the purpose of this study is to evaluate the usefulness of ELPS for superficial laryngo-pharyngeal cancer.


METHODS
Seventy five consecutive patients with 104 fresh superficial laryngo-pharyngeal cancers are included in this study. Under general anesthesia, a specially-designed curved laryngoscope was inserted to create a working space in the pharyngeal lumen. A magnifying endoscope was inserted transorally to visualize the field and a head & neck surgeon dissected the lesion using the combination of the orally-inserted curved grasping forceps and electrosurgical needle knife in both hands. The safely, functional outcomes, and oncologic outcomes of ELPS were evaluated retrospectively.


RESULTS
Median operation time per lesion was 35 min. Post-operative bleeding occurred in 3 cases and temporal subcutaneous emphysema occurred in 10 cases. No vocal fold impairment occurred after surgery. The median fasting period was 2 days and all patients except one have a normal diet with no limitations. Local recurrence occurred in 1 case, and the 3-year overall survival rate and the 3-year disease specific survival rate was 90% and 100%, respectively.


CONCLUSIONS
ELPS is a hybrid of head and neck surgery and gastrointestinal endoscopic treatment, and enjoys the merit of both procedures. ELPS makes it possible to perform minimally-invasive surgery, preserving both the swallowing and phonation functions.
Department of Otolaryngology-Head and Neck Surgery, Graduate of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan. tateya@ent.kuhp.kyoto-u.ac.jp.
Ichiro
I
Tateya
Department of Clinical Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Manabu
M
Muto
Department of Gastroenterology and Hepatology, Graduate of Medicine, Kyoto University, Kyoto, Japan.
Shuko
S
Morita
Department of Gastroenterology and Hepatology, Graduate of Medicine, Kyoto University, Kyoto, Japan.
Shin'ichi
S
Miyamoto
Department of Clinical Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tomomasa
T
Hayashi
Department of Clinical Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Makiko
M
Funakoshi
Department of Clinical Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ikuo
I
Aoyama
Department of Medical Supply, Kyoto University Hospital, Kyoto, Japan.
Hirokazu
H
Higuchi
Department of Otolaryngology-Head and Neck Surgery, Graduate of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
Shigeru
S
Hirano
Department of Otolaryngology-Head and Neck Surgery, Graduate of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
Morimasa
M
Kitamura
Department of Otolaryngology-Head and Neck Surgery, Graduate of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
Seiji
S
Ishikawa
Department of Otolaryngology-Head and Neck Surgery, Graduate of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
Yo
Y
Kishimoto
Department of Otolaryngology-Head and Neck Surgery, Graduate of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
Mami
M
Morita
Department of Otolaryngology-Head and Neck Surgery, Graduate of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
Juichi
J
Ito
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002278:Carcinoma in Situ / Q000401:mortality / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000601:surgery; D004598:Electrosurgery; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000601:surgery*; D020704:Laryngoscopes; D008297:Male; D008875:Middle Aged; D062048:Narrow Band Imaging; D010610:Pharyngeal Neoplasms / Q000401:mortality / Q000601:surgery*; D012189:Retrospective Studies
ELPS; ESD; NBI; Narrow band imaging; Pharyngeal cancer; Transoral