Squamous cell carcinoma arising in a mature cystic teratoma invading the sigmoid colon: a rare presentation.
We discuss a rare presentation of malignant teratoma in a 63-year-old woman who was admitted to accident and emergency with abdominal distension, bloody diarrhoea and peritonitis. CT of the abdomen and pelvis showed free air in the abdomen and a gas-fluid filled cavity measuring 12×6 cm in the mid-pelvis with possible fistulation that was suspicious for malignancy. A 10×12 cm ruptured dermoid cyst was found intraoperatively, which was adherent to the bowel wall. Bulky lymph nodes were also appreciated. The surgeon suspected a metastatic malignant teratoma, and a Hartmann's procedure, total abdominal hysterectomy and bilateral salpingoopherectomy were performed with clearance of the para-aortic lymph nodes. Subsequent histological analysis revealed a squamous cell carcinoma arising from an ovarian malignant teratoma. The patient went on to have carboplatin and paclitaxel chemotherapy and is alive at 6 months follow-up.
Maidstone and Tunbridge Wells NHS Trust, Maidstone, UK.
Alena Talia
AT
Gooneratne
Maidstone and Tunbridge Wells NHS Trust, Maidstone, UK.
Alexander Owen
AO
James
Maidstone and Tunbridge Wells NHS Trust, Maidstone, UK.
Jyoti
J
Gupta
Tunbridge Wells Hospital, Tunbridge Wells, UK.
Yasser
Y
Abdulaal
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000209:etiology*; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000628:therapy; D017239:Paclitaxel / Q000008:administration & dosage; D010538:Peritonitis / Q000209:etiology; D012811:Sigmoid Neoplasms / Q000150:complications*; D013724:Teratoma / Q000150:complications*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D016190:Carboplatin; D017239:Paclitaxel