Effects of captopril, spironolactone, and simvastatin on the cardiovascular system of non-diseased Wistar rats.
Department of Pathophysiology, School of Medicine, Comenius University, Bratislava, Slovak Republic; 3rd Clinic of Internal Medicine, School of Medicine, Comenius University, Bratislava, Slovak Republic; Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovak Republic; Center of Excellence NOREG, Slovak Republic. Electronic address: fedor.simko@fmed.uniba.sk.
Fedor
F
Simko
Center of Excellence NOREG, Slovak Republic; Institute of Normal and Pathological Physiology, Slovak Academy of Sciences, Bratislava, Slovak Republic.
Olga
O
Pechanova
Department of Pathophysiology, School of Medicine, Comenius University, Bratislava, Slovak Republic.
Kristina
K
Krajcirovicova
Department of Pathophysiology, School of Medicine, Comenius University, Bratislava, Slovak Republic.
Jana
J
Matuskova
Department of Medical Biochemistry, 2nd School of Medicine, Charles University, Prague, Czech Republic.
Vaclav
V
Pelouch
Department of Physiology, School of Medicine, Charles University, Hradec Kralove, Czech Republic.
Michaela
M
Adamcova
Department of Pathophysiology, School of Medicine, Comenius University, Bratislava, Slovak Republic; Center of Excellence NOREG, Slovak Republic.
Ludovit
L
Paulis
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000494:pharmacology*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D002216:Captopril / Q000494:pharmacology*; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology*; D008297:Male; D000451:Mineralocorticoid Receptor Antagonists / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D019821:Simvastatin / Q000494:pharmacology*; D013148:Spironolactone / Q000494:pharmacology*; D020257:Ventricular Remodeling / Q000187:drug effects / Q000502:physiology
D000806:Angiotensin-Converting Enzyme Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000451:Mineralocorticoid Receptor Antagonists; D013148:Spironolactone; D002216:Captopril; D019821:Simvastatin
Captopril; Endothelial function; Fibrosis; Non-diseased heart; Protection; Protein remodeling; Simvastatin; Spironolactone