Exposure to dust-bound PAHs and associated carcinogenic risk in primitive and traditional cooking practices in Pakistan.
The aim of this study was to determine the abundance and distribution of polycyclic aromatic hydrocarbons (PAHs) in dust samples collected from the selected professional cooking workplaces (WCs) and residential household cooking areas (WRs), where traditional and primitive cooking practices are still prevelent. Another aim of this study was to investigate the carcinogenic risk for Pakistani human exposure to dust-bound PAHs via the routes of inhalation, ingestion, and dermal contact. Generally, the concentration of individual congeners of PAHs in surface dust samples of WC sites was higher than those measured in WR sites (p < 0.05). The benzo(a)pyrene (B(a)P), a very high carcinogenic compound, was present in the dust samples from WC sites in the highest mean concentration (630 ng g(-1) dry weight (d.w.)). The BaP mean concentration in WC workplaces was almost eight times higher than the mean value found in WR exposure sites. Moreover, the average concentration of ∑PAHs, combustion origin PAHs (∑COMB) and sum total of 7-carcinogenic PAHs (∑7-carcinogens) were also significantly higher in WC dusts samples than that in WR workplaces. Principal component analysis (PCA) and diagnostic ratios suggested coal/wood combustion as major PAH emission sources in both exposure sites. The average incremental lifetime cancer risk (ILCR) suggested a moderate to potential high cancer risk for adults and children exposed to dust-bound PAHs in both exposure sites, in particular via both dermal and ingestion contact pathways.
Environmental Biology and Ecotoxicology Laboratory, Department of Environmental Sciences, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad, 45320, Pakistan, dr.atifkamal@yahoo.com.
Atif
A
Kamal
Riffat Naseem
RN
Malik
Tania
T
Martellini
Alessandra
A
Cincinelli
D000328:Adult; D001564:Benzo(a)pyrene / Q000032:analysis / Q000633:toxicity; D002273:Carcinogens / Q000032:analysis* / Q000633:toxicity; D002648:Child; D003031:Coal / Q000032:analysis / Q000633:toxicity; D003296:Cooking; D004391:Dust / Q000032:analysis*; D004781:Environmental Exposure / Q000032:analysis*; D006801:Humans; D008962:Models, Theoretical; D010154:Pakistan; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis* / Q000633:toxicity; D018570:Risk Assessment
D002273:Carcinogens; D003031:Coal; D004391:Dust; D011084:Polycyclic Aromatic Hydrocarbons; D001564:Benzo(a)pyrene