Clinical characteristics and treatment outcomes of primary and recurrent malignancy involving the salivary glands in children.
Malignant salivary gland neoplasms are rare in children. The purpose of this study was to present our experience in the treatment of primary and recurrent salivary gland neoplasm and contribute to the fractional available data.



All patients <18 years, treated between June 2005 and April 2014 were included in this study.



The parotid gland was the most common site for both primary (n = 18) and recurrent (n = 6) tumors and mucoepidermoid carcinoma, low or intermediate grade, main histological type. Surgical excision was performed in all patients, of which 13 patients received radiotherapy. Lymph node metastasis was present in 3 patients with primary tumor, which were assessed accurately on frozen section examination. Local recurrence occurred in 1 patient with primary tumor and all patients are alive.



Surgery is the prime modality of treatment for malignant salivary gland neoplasm and is associated with excellent outcomes. The role of lymph node sampling and frozen section examination needs further evaluation in identifying lymph node metastasis. © 2015 Wiley Periodicals, Inc. Head Neck 38: 852-856, 2016.
Department of Surgical Oncology, Division of Pediatric Surgical Oncology, Tata Memorial Centre, Bombay, India.
Sajid S
SS
Qureshi
Department of Surgical Oncology, Division of Pediatric Surgical Oncology, Tata Memorial Centre, Bombay, India.
Monica
M
Bhagat
Department of Surgical Oncology, Division of Pediatric Surgical Oncology, Tata Memorial Centre, Bombay, India.
Nitin
N
Singhal
Department of Surgical Oncology, Division of Pediatric Surgical Oncology, Tata Memorial Centre, Bombay, India.
Nitin
N
Tathe
Department of Radiology, Tata Memorial Centre, Bombay, India.
Seema
S
Kembhavi
Department of Radiation Oncology, Tata Memorial Centre, Bombay, India.
Siddharth
S
Laskar
Department of Pathology, Tata Memorial Centre, Bombay, India.
Mukta
M
Ramadwar
Department of Plastic and Reconstructive Surgery, Tata Memorial Centre, Bombay, India.
Prabha
P
Yadav
D000293:Adolescent; D001706:Biopsy; D018277:Carcinoma, Mucoepidermoid / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D012469:Salivary Glands / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome
children; malignant; mucoepidermoid carcinoma; salivary gland neoplasm; surgery