[Insufficient evidence of the effect of the low FODMAP diet on irritable bowel syndrome].
The low FODMAP (Fermentable Oligo-, Di- and Monosaccharides and Polyoles) diet (LFD) allegedly reduces symptoms of irritable bowel syndrome (IBS). Eleven studies have examined the effects of LFD on IBS. Most studies reported a symptomatic effect, but methodological weaknesses such as lack of relevant control group and of proper blinding means that a placebo response cannot be excluded. No studies have examined the effect of the important reintroduction phase nor the effects of LFD on IBS patients in primary care. Evidence suggests that intake of high dose FODMAP can induce gastrointestinal symptoms, but the clinical relevance of this is doubtful.
Medicinsk Afdeling, Køge Sygehus, Lykkebækvej 1, 4600 Køge. lkrr@regionsjaelland.dk.
Laura Rindom
LR
Krogsgaard
Malene
M
Lyngesen
Peter
P
Bytzer
D050528:Diet, Carbohydrate-Restricted; D004187:Disaccharides / Q000009:adverse effects; D019317:Evidence-Based Medicine; D005285:Fermentation; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000178:diet therapy*; D009005:Monosaccharides / Q000009:adverse effects; D009844:Oligosaccharides / Q000009:adverse effects; D011108:Polymers / Q000009:adverse effects; D013402:Sugar Alcohols / Q000009:adverse effects; D016896:Treatment Outcome
D004187:Disaccharides; D009005:Monosaccharides; D009844:Oligosaccharides; D011108:Polymers; D013402:Sugar Alcohols; C024617:polyol