[Study impacto: Descriptive analyzis of pharmacist's clinical practice in onco-hematology].
Pharmaceutical analyses of chemotherapy prescriptions by hospital pharmacists are activities codified by regulation and rules (bon usage). The involvement of the pharmacists in clinical pharmacy activities in the oncology setting is not clearly identified, justifying the development of a mapping of these activities from a questionnaire addressed to the professionals. One hundred and seven centers have participated to this study at the national level (overall participation rate of 32.4%). More than 95% of them used a computerized ordering system and three quarter of them submit the introduction of new compounds to an analysis by the drug therapeutic committee. Prescription analysis allowed detecting around 2% of errors from the current prescription. Clinical pharmacist participates to tumor boards of onco-hematology (RCP) at a level of 46% for senior pharmacist and 42% for junior pharmacist. This involvement in the RCP allowed anticipating protocol's modification and temporary used authorization. Ninety-two percent of the senior pharmacists estimate that they highlight the risk of no reimbursement for prescription out of the guideline during RCP, resulting to a modification of the prescription for 40% of them. This level of intervention is lower with respectively 64% and 10% for the juniors. This study underlines the expert value of the clinical pharmacist dedicated to oncology setting in pre and post analysis prescriptions. It could be targeted by a prospective analysis of both clinical and pharmacoeconomics impact of these interventions.
Pharmacie Pitié-Salpêtrière, 47, boulevard de l'hôpital, 75013 Paris, France. Electronic address: leguenro@gmail.com.
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Le Guen
Pharmacie St-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.
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Madelaine
Pharmacie Bretonneau, 2, boulevard Tonnelle, 37044 Tours, France.
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JF
Tournamille
Pharmacie Pitié-Salpêtrière, 47, boulevard de l'hôpital, 75013 Paris, France.
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Bellanger
Pharmacie Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny 94100 Créteil, France.
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Astier
Université Aix-Marseille II, UMR 911-CRO2 faculté de médecine, 27, boulevard Jean-Moulin 13385 Marseille, France.
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Braguer
Pharmacie, CHU Caen, avenue de la Côte-de-Nacre, 14033 Caen, France.
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Ollivier
Pharmacie Cochin, 27, rue du Faubourg-St-Jacques, 75014 Paris, France.
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Bardin
Pharmacie IGR, 114, rue Édouard-Vaillant, 94805 Villejuif, France; Faculté de pharmacie, université Paris Descartes, 4, rue de l'Observatoire, 75006, Paris, France.
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Lemare
Pharmacie, CRLC Henri-Becquerel, rue d'Amiens, 76038 Rouen, France.
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Daouphars
Pharmacie, CRLC Val-d'Aurelle-Parc Euromédecine 208, rue des Apothicaires, 34298 Montpellier, France.
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Pinguet
Pharmacie, centre Léon-Bérard, 28, rue Laennec, 69373 Lyon, France.
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JF
Latour
Pharmacie, CHU Nancy, 29, avenue du Maréchal-de-Lattre-de-Tassigny, 54000 Nancy, France.
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Vigneron
Pharmacie Pitié-Salpêtrière, 47, boulevard de l'hôpital, 75013 Paris, France; Faculté de pharmacie, université Paris Descartes, 4, rue de l'Observatoire, 75006, Paris, France.
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Tilleul
D011307:Drug Prescriptions; D005602:France; D019538:Health Care Surveys; D006405:Hematology; D006801:Humans; D008495:Medical Oncology; D010595:Pharmacists; D010607:Pharmacy Service, Hospital / Q000458:organization & administration*; D024382:Professional Role; D011446:Prospective Studies
Analyse pharmaceutique; Cancérologie; Iatrogeny; Iatrogénie; Intervention pharmaceutique; Medical staff; Onco-hematology; Pharmaceutical analysis; Réunion de concertation pluridisciplinaire