Nickel-catalyzed direct amination of arenes with alkylamines.
The efficient nickel-catalyzed direct amination of arenes with simple alkylamines has been achieved with the assistance of a bidentate directing group through sp(2) C-H bond functionalization. Preliminary mechanistic investigations indicate that the reaction probably proceeds through a Ni(I)/Ni(III) catalytic pathway.
Qiangqiang
Q
Yan
Zhengkai
Z
Chen
Wenlong
W
Yu
Hong
H
Yin
Zhanxiang
Z
Liu
‡State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Yuhong
Y
Zhang