Primary osteosarcoma of the clavicle and the perils of bone biopsy.
We present a rare case of delayed diagnosis of osteosarcoma of the medial clavicle in a young man. He presented following a pathological fracture with a falsely reassuring core and fine-needle aspiration biopsy. The initial biopsy was suggestive of an aneurysmal bone cyst and was therefore treated conservatively without further follow-up. The rapid increase in size over the next 8 months triggered a repeat presentation and subsequent repeat biopsy. The open biopsy confirmed high-grade osteosarcoma and the patient underwent claviculectomy with neoadjuvant chemotherapy.
Department of Orthopaedics and Trauma, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
William J
WJ
Cundy
Department of Cytopathology, SA Pathology, Adelaide, South Australia, Australia.
Christopher
C
Carter
Department of Cytopathology, SA Pathology, Adelaide, South Australia, Australia.
Deepak
D
Dhatrak
Department of Orthopaedics and Trauma, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Mark
M
Clayer
D000328:Adult; D044963:Biopsy, Fine-Needle; D001859:Bone Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D002968:Clavicle / Q000293:injuries* / Q000473:pathology*; D057210:Delayed Diagnosis; D005188:False Negative Reactions; D005598:Fractures, Spontaneous / Q000209:etiology*; D006801:Humans; D008297:Male; D012516:Osteosarcoma / Q000150:complications / Q000473:pathology* / Q000628:therapy