Valuation of Child Health-Related Quality of Life in the United States.
Many economic analyses fail to incorporate evidence on child health-related quality of life because of a paucity of quality-adjusted life year (QALY) estimates. This health valuation study is the first to summarize the EQ-5D-Y on a QALY scale. Drawn from a nationally representative panel, 5207 adult respondents were asked to choose between two losses in child health-related quality of life. Based on their choices, a 1-year increase in child pain/discomfort from 'some' to 'a lot' equals a loss of 4 QALYs (95% CI, 3.8-4.4). Likewise, a 1-year increase in child anxiety/depression from 'a bit' to 'very worried, sad, or unhappy' equals a loss of 2 QALYs (95% CI, 1.9-2.2). These findings enable the integration of child-reported outcomes with adult preferences to inform economic analysis. Results inform both clinical practice and resource allocation decisions by enhancing understanding of difficult tradeoffs in child-reported outcomes. Copyright © 2015 John Wiley & Sons, Ltd.
Moffitt Cancer Center and University of South Florida, Tampa, FL, USA.
Benjamin M
BM
Craig
School of Public Health, University of Bielefeld, Bielefeld, Germany.
Wolfgang
W
Greiner
Brown School and Institute for Public Health, Washington University in St. Louis, St. Louis, MO, USA.
Derek S
DS
Brown
University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Bryce B
BB
Reeve
D000328:Adult; D002648:Child; D000067576:Child Health; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D017059:Models, Econometric; D011788:Quality of Life; D019057:Quality-Adjusted Life Years; D011795:Surveys and Questionnaires; D014481:United States
child HRQoL; discrete choice experiments; health-related quality of life; patient-reported outcomes; quality-adjusted life years