Enterobacteriaceae isolates from the oral cavity of workers in a Brazilian oncology hospital.
The evaluation of workers as potential reservoirs and disseminators of pathogenic bacteria has been described as a strategy for the prevention and control of healthcare-associated infections (HAIs). The aim of this study was to evaluate the presence of Enterobacteriaceae in the oral cavity of workers at an oncology hospital in the Midwest region of Brazil, as well as to characterize the phenotypic profile of the isolates. Saliva samples of 294 workers from the hospital's healthcare and support teams were collected. Microbiological procedures were performed according to standard techniques. Among the participants, 55 (18.7%) were colonized by Enterobacteriaceae in the oral cavity. A total of 64 bacteria were isolated, including potentially pathogenic species. The most prevalent species was Enterobacter gergoviae (17.2%). The highest rates of resistance were observed for β-lactams, and 48.4% of the isolates were considered multiresistant. Regarding the enterobacteria isolated, the production of ESBL and KPC was negative. Nevertheless, among the 43 isolates of the CESP group, 51.2% were considered AmpC β-lactamase producers by induction, and 48.8% were hyper-producing mutants. The significant prevalence of carriers of Enterobacteriaceae and the phenotypic profile of the isolates represents a concern, especially due to the multiresistance and production of AmpC β-lactamases.
Public Health and Tropical Pathology Institute, Federal University of Goiás, Goiânia, Goiás, Brazil.
Lara Stefânia Netto de Oliveira
LS
Leão-Vasconcelos
Central Public Health Laboratory, Dr. Giovanni Cysneiros/LACEN, State Department of Goiás, Goiânia, Goiás, Brazil.
Ana Beatriz Mori
AB
Lima
Nursing School, Federal University of Goiás, Goiânia, Goiás, Brazil.
Dayane de Melo
Dde M
Costa
Nursing School, Federal University of Goiás, Goiânia, Goiás, Brazil.
Larissa Oliveira
LO
Rocha-Vilefort
Biomedicine Department, Pontifical Catholic University of Goiás, Goiânia, Goiás, Brazil.
Ana Claúdia Alves de
AC
Oliveira
Emergency Hospital of Goiânia, State Department of Goiás, Goiânia, Goiás, Brazil.
Nádia Ferreira
NF
Gonçalves
Public Health and Tropical Pathology Institute, Federal University of Goiás, Goiânia, Goiás, Brazil.
José Daniel Gonçalves
JD
Vieira
Nursing School, Federal University of Goiás, Goiânia, Goiás, Brazil.
Marinésia Aparecida
MA
Prado-Palos
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001938:Brazil; D002173:Cancer Care Facilities; D003430:Cross-Sectional Studies; D004197:Disease Reservoirs / Q000382:microbiology; D004755:Enterobacteriaceae / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification* / Q000378:metabolism; D006801:Humans; D008826:Microbial Sensitivity Tests; D009055:Mouth / Q000382:microbiology*; D010564:Personnel, Hospital / Q000706:statistics & numerical data*; D010641:Phenotype
D000900:Anti-Bacterial Agents