A new ent-kaurane diterpenoid from Ixora amplexicaulis.
A new ent-kaurane diterpenoid, 6α,16α-dihyroxy-ent-kaurane (1), was isolated from the stems of Ixora amplexicaulis, together with (24R)-6β-hydroxy-24-ethyl-cholest-4-en-3-one (2), 7β-hydroxysitosterol (3), maslinic acid (4), 3,3'-bis(3,4-dihydro-4-hydroxy-6-methoxy-2H-1-benzopyran) (5) and protocatechuric acid (6). Their structures were established by extensive spectroscopic analysis, including 2D NMR techniques. Compounds 2-5 were isolated from the genus Ixora for the first time and 6 obtained originally from I. amplexicaulis.
a School of Chemistry and Chemical Engineering, Yunnan Normal University , Kunming 650500 , P.R. China.|b School of Pharmacy, Kunming Medical University , Kunming 650500 , P.R. China.
Lijun
L
Chen
a School of Chemistry and Chemical Engineering, Yunnan Normal University , Kunming 650500 , P.R. China.
Rui
R
Zhan
a School of Chemistry and Chemical Engineering, Yunnan Normal University , Kunming 650500 , P.R. China.
Jinhe
J
Jiang
b School of Pharmacy, Kunming Medical University , Kunming 650500 , P.R. China.
Yan
Y
Zhang
c Dehong Teachers College , Mangshi 678400 , P.R. China.
Yi
Y
Dong
a School of Chemistry and Chemical Engineering, Yunnan Normal University , Kunming 650500 , P.R. China.
Yegao
Y
Chen
D002783:Cholestenones; D045786:Diterpenes, Kaurane / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D018547:Plant Stems / Q000737:chemistry; D019666:Rubiaceae / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared
D002783:Cholestenones; D045786:Diterpenes, Kaurane; C000475:cholest-4-en-3-one
Ixora amplexicaulis; Rubiaceae; ent-kaurane diterpenoid