Soybean β-conglycinin improves carbohydrate and lipid metabolism in Wistar rats.
The effects of dietary soybean β-conglycinin on lipid metabolism and energy consumption were studied in Wistar adult rats. Rats were fed, a diet containing casein (control group) or β-conglycinin (β-conglycinin group), for 4 weeks. Carbohydrate consumption was higher and fat consumption was lower in the β-conglycinin group than in the control group, whereas the total energy consumption was the same between the two groups. Serum adiponectin was higher in the β-conglycinin group than in the control group. Serum triacylglycerol levels in the β-conglycinin group were significantly lower than those in the control group. The secretion rate of triacylglycerols from the liver after the administration of tyloxapol, an inhibitor of lipolysis, was significantly lower in the β-conglycinin group than in the control group. These results suggest the possibility that β-conglycinin exerts hypolipidemic effects through an acceleration in carbohydrate consumption associated with an increase in adiponectin in rats.
a Laboratory of Food and Biomolecular Science , Graduate School of Agricultural Science, Tohoku University , Sendai , Japan.
Nao
N
Inoue
Yuka
Y
Fujiwara
Masaki
M
Kato
Asuwa
A
Funayama
Nozomi
N
Ogawa
Nobuhiko
N
Tachibana
Mitsutaka
M
Kohno
Ikuo
I
Ikeda
D052242:Adiponectin / Q000378:metabolism; D000818:Animals; D052179:Antigens, Plant / Q000008:administration & dosage* / Q000737:chemistry; D050260:Carbohydrate Metabolism / Q000187:drug effects*; D004734:Energy Metabolism; D005916:Globulins / Q000008:administration & dosage* / Q000737:chemistry; D050356:Lipid Metabolism / Q000187:drug effects*; D051381:Rats; D055314:Seed Storage Proteins / Q000008:administration & dosage* / Q000737:chemistry; D030262:Soybean Proteins / Q000008:administration & dosage* / Q000737:chemistry; D013025:Glycine max / Q000737:chemistry; D014280:Triglycerides / Q000097:blood
D052242:Adiponectin; D052179:Antigens, Plant; D005916:Globulins; D055314:Seed Storage Proteins; D030262:Soybean Proteins; D014280:Triglycerides; C013894:beta-conglycinin protein, Glycine max
adiponectin; energy consumption; soy protein; β-conglycinin