[The role of the Consultative and Diagnostic Centre "Healthy Nutrition" in the diagnosis and nutritional prevention of non-communicable diseases].
In a consultative and diagnostic center "Healthy Nutrition" of Institute of Nutrition the nutritional status of 3500 patients (mean age 48.4 ± 0.3 years) liv- ing in the Moscow region, using a system Nutritest IP-3, including genomic analysis has been examined. In the analysis of dietary intake by an average review, increased energy intake due to excess intake of the total (44.2% energy) and saturated fat (13.6%) has been shown. 30.0% of patients were overweight and 34.1% were obese. Osteopenia was detected in 31.0% of men and 25.0% women, osteoporosis--20.9% and 30.3%, respectively. Analysis of the results of biochemical studies revealed increased cholesterol in 68.7% of patients, LDL cholesterol--at 63.9%, triglycerides-- at 22.5%, glucose--at 29.4%. The frequency of the occurrence of risk alleles of genes associated with the development of obesity and type 2 diabetes mellitus was: 47.8%--for the polymorphism rs9939609 (FTO gene), 8.3%--for polymorphism rs4994 (gene ADRB3), 60.2%--for the polymorphism rs659366 (gene UCP2), 36.6%--for the rs5219 polymorphism in the gene of ATP-dependent potassium channel.
A V
AV
Pogozheva
E Yu
EY
Sorokina
A K
AK
Baturin
E V
EV
Peskova
O N
ON
Makurina
L G
LG
Levin
S Kh
SKh
Soto
T A
TA
Aristarkhova
M M
MM
Korosteleva
N N
NN
Denisova
T N
TN
Solntseva
I V
IV
Aleshina
M A
MA
Toboleva
L A
LA
Redzyuk
A V
AV
Polyakova
D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000175:diagnosis* / Q000235:genetics / Q000517:prevention & control*; D002149:Energy Intake; D005260:Female; D006801:Humans; D008297:Male; D009752:Nutritional Status; D009765:Obesity / Q000097:blood / Q000175:diagnosis* / Q000235:genetics / Q000517:prevention & control*; D011110:Polymorphism, Genetic