Michael Addition of Soft Carbon Nucleophiles to Alkylidene Isoxazol-5-ones: A Divergent Entry to β-Branched Carbonyl Compounds.
A novel, divergent strategy toward the synthesis of β-branched (and linear) carbonyl compounds is developed by taking advantage of alkylidene isoxazol-5-ones as key building blocks. The yields obtained range from good to excellent, therefore making the described methods attractive options for building such molecules.
Institute of Chemistry, State University of Campinas, 13083-970, C.P. 6154, Campinas, SP, Brazil.
Naylil M R
NM
Capreti
Institute of Chemistry, State University of Campinas, 13083-970, C.P. 6154, Campinas, SP, Brazil.
Igor D
ID
Jurberg