Paternal phylogeography and genetic diversity of East Asian goats.
This study was a first analysis of paternal genetic diversity for extensive Asian domestic goats using SRY gene sequences. Sequencing comparison of the SRY 3'-untranslated region among 210 Asian goats revealed four haplotypes (Y1A, Y1B, Y2A and Y2B) derived from four variable sites including a novel substitution detected in this study. In Asian goats, the predominant haplotype was Y1A (62%) and second most common was Y2B (30%). Interestingly, the Y2B was a unique East Asian Y chromosomal variant, which differentiates eastern and western Eurasian goats. The SRY geographic distribution in Myanmar and Cambodia indicated predominant the haplotype Y1A in plains areas and a high frequency of Y2B in mountain areas. The results suggest recent genetic infiltration of modern breeds into South-East Asian goats and an ancestral SRY Y2B haplotype in Asian native goats.
Laboratory of Animal Breeding and Genetics, Graduate School of Agricultural Science, Kobe University, Kobe, 657-8501, Japan.
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A
Waki
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S
Sasazaki
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E
Kobayashi
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H
Mannen
D000818:Animals; D002160:Cambodia; D004272:DNA, Mitochondrial / Q000235:genetics; D019143:Evolution, Molecular; D005202:Asia, Eastern; D024282:Genes, sry; D014644:Genetic Variation; D006041:Goats / Q000235:genetics*; D006239:Haplotypes; D008297:Male; D002052:Myanmar; D058974:Phylogeography; D017422:Sequence Analysis, DNA; D014998:Y Chromosome
D004272:DNA, Mitochondrial
Capra hircus; SRY; Y chromosome; genetic structure; haplotype; untranslated region