Atypical Spitz Tumor Arising on a Congenital Linear Plaque-Type Blue Nevus: A Case Report With a Review of the Literature on Plaque-Type Blue Nevus.
The plaque-type blue nevus (PTBN) is a rare variant of blue nevus, of which only a few reports are described. A nodular growth within a preexistent PTBN should always alert to the possibility of malignant transformation. The authors report the first case of an atypical Spitz tumor arising on a congenital linear PTBN in a 60-year-old woman. The diagnosis of "atypical Spitz tumor" is here used to describe a microscopic "gray zone" in which it is not possible to differentiate with adequate certainty between a Spitz nevus and a spitzoid melanoma. This report adds to and summarizes the small body of literature describing PTBN and discusses diagnostic and clinical implications.
*Department of Health Sciences (DISSAL), Section of Dermatology, IRCSS-AOU S. Martino-IST, University of Genoa, Genoa, Italy; †Department of Surgical and Morphological Sciences, Anatomic Pathology Division, IRCSS-AOU S. Martino-IST, University of Genoa, Genoa, Italy; and ‡Dermatopathologie Friedrichshafen, Friedrichshafen, Germany.
Franco
F
Rongioletti
Antonio
A
Guadagno
Caterina
C
Campisi
Francesco
F
Cabiddu
Heinz
H
Kutzner
Aurora
A
Parodi
Roberto
R
Fiocca
D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D018329:Nevus, Blue / Q000151:congenital / Q000473:pathology*; D018332:Nevus, Epithelioid and Spindle Cell / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*