Structural study of endopelvic fascia in prostates of different weights. Anatomic study applied to radical prostatectomy.
OBJECTIVE
To evaluate the structure of the endopelvic fascia in prostates of different weights.


METHODS
We studied 10 patients with BPH (prostates> 90 g); 10 patients with prostate adenocarcinoma (PAC) (prostates< 60 g) and five young male cadavers (control group). During the surgery a small sample of endopelvic fascia was obtained. We analyzed elastic fibers, collagen and smooth muscle. The stereological analysis was done with the Image Pro and Image J programs. Means were statistically compared using the one-way ANOVA with the Bonferroni test and a p<0.05 was considered statistically significant.


RESULTS
The mean of the prostate weight was 122 g in BPH patients, 53.1g in PAC patients and 18.6g in control group. Quantitative analysis documented that there are no differences (p=0.19) in Vv of elastic fibers and in Vv of type III collagen (p=0.88) between the three groups. There was a significant difference (p=0<0.0001) in the quantification of SMC in patients with prostates > 90 g (mean=9.61%) when compared to patients with prostates < 60 g (mean=17.92%) and with the control group (mean=33.35%).


CONCLUSIONS
There are differences in endopelvic fascia structure in prostates> 90 g, which can be an additional factor for pre-operatory evaluation of radical prostatectomy.
UERJ, Brazil.
Helce Riberio
HR
Julio Junior
UERJ, Brazil.
Suelen Freitas
SF
Costa
UERJ, Rio de Janeiro, RJ, Brazil.
Waldemar Silva
WS
Costa
UERJ, Rio de Janeiro, RJ, Brazil.
Francisco Jose Barcellos
FJ
Sampaio
UERJ, Rio de Janeiro, RJ, Brazil.
Luciano Alves
LA
Favorito
D000230:Adenocarcinoma / Q000601:surgery; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D003094:Collagen / Q000032:analysis; D004547:Elastic Tissue / Q000033:anatomy & histology; D005205:Fascia / Q000033:anatomy & histology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000033:anatomy & histology; D009929:Organ Size; D010388:Pelvis / Q000033:anatomy & histology*; D011467:Prostate / Q000033:anatomy & histology* / Q000601:surgery; D011468:Prostatectomy / Q000379:methods*; D011470:Prostatic Hyperplasia / Q000601:surgery; D011471:Prostatic Neoplasms / Q000601:surgery
D003094:Collagen