A bioresponsive controlled-release bioassay based on aptamer-gated Au nanocages and its application in living cells.
A novel controlled-release bioassay for highly sensitive and selective detection of intracellular ATP was developed based on positive charge-modified Au nanocages capped with an aptamer molecular gate, and it was used successfully for fluorescence microscopy imaging of ATP in living cells.
Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China. wangwei9612@126.com xiliangluo@hotmail.com.
Wei
W
Wang
Chen
C
Chen
Xiaoxiao
X
Li
Shiying
S
Wang
Xiliang
X
Luo
D000255:Adenosine Triphosphate / Q000032:analysis* / Q000737:chemistry; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D001681:Biological Assay; D045744:Cell Line, Tumor; D006046:Gold / Q000737:chemistry*; D006801:Humans; D008856:Microscopy, Fluorescence; D049329:Nanostructures / Q000737:chemistry*
D052157:Aptamers, Nucleotide; D006046:Gold; D000255:Adenosine Triphosphate