Subjective sleep quality in sarcoidosis.
BACKGROUND
Poor sleep is common among patients with medical disorders. Sleep disturbances can be a cause of fatigue and poor quality of life for patients suffering from sarcoidosis. Studies on subjective sleep quality or prevalence of insomnia have not been reported so far.


OBJECTIVE
The aim of this study was to investigate the subjectively reported sleep quality and its relation to psychological and physical factors in sarcoidosis patients.


METHODS
1197 patients from Germany diagnosed with sarcoidosis were examined using the Pittsburgh Sleep Quality Index (PSQI), the Medical Research Council (MRC) dyspnea scale, the Hospital Anxiety and Depression Scale (HADS) and the Multidimensional Fatigue Inventory (MFI).


RESULTS
802 patients (67%) had PSQI global scores >5, indicating subjectively poor quality of sleep. The mean PSQI score was 7.79 ± 4.00. Women reported a significantly inferior individual quality of sleep than men. The subjective quality of sleep was lowered significantly with increasing dyspnea for men and women. 294 patients (25%) had PSQI global scores >10 usually found in patients with clinically relevant insomnia. In this group 86% had high values for fatigue, 69% for anxiety, and 59% for depression. The prevalence of known sleep apnea was 8.7% and 15.7% for restless legs.


CONCLUSIONS
Poor subjective sleep quality in sarcoidosis patients is about twice as common as in the general population and is associated with fatigue, anxiety, depression and dyspnea. Questions about sleep complaints should therefore be included in the management of sarcoidosis.
Department of Respiratory Medicine, University of Leipzig, Leipzig 04103, Germany. Electronic address: andrea.bosse-henck@medizin.uni-leipzig.de.
Andrea
A
Bosse-Henck
Department of Respiratory Medicine, University of Leipzig, Leipzig 04103, Germany.
Hubert
H
Wirtz
Department of Medical Psychology and Medical Sociology, University of Leipzig, Leipzig 04103, Germany.
Andreas
A
Hinz
D000328:Adult; D000368:Aged; D001007:Anxiety / Q000150:complications; D003863:Depression / Q000150:complications; D004417:Dyspnea / Q000150:complications; D005221:Fatigue / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012507:Sarcoidosis / Q000150:complications*; D012890:Sleep; D007319:Sleep Initiation and Maintenance Disorders / Q000209:etiology; D012893:Sleep Wake Disorders / Q000209:etiology*; D011795:Surveys and Questionnaires
Dyspnea; Fatigue; Insomnia; Sarcoidosis; Subjective sleep quality