Nickel N-heterocyclic carbene catalyzed C-C bond formation: a new route to aryl ketones.
A novel nickel N-heterocyclic carbene catalyzed cross-coupling reaction of aryl aldehydes with boronic esters for the synthesis of aryl ketones was developed. This reaction provides a mild, practical method toward aryl ketones, which are versatile intermediates and building blocks in organic synthesis.
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, Yunnan, 650500 (P. R. China). gulijun2005@126.com.|Key Laboratory of Comprehensive Utilization of Mineral Resources in Ethnic Regions, Yunnan Minzu University, Yunnan Minzu University, Kunming, Yunnan, 650500 (P. R. China). gulijun2005@126.com.
Li-Jun
LJ
Gu
New United Group Company Limited, Changzhou, Jiangsu, 213166 (P. R. China).
Cheng
C
Jin
Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming, Yunnan, 650500 (P. R. China).
Hong-Tao
HT
Zhang
D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*
D007659:Ketones; C030011:carbene; D009532:Nickel; D008697:Methane
CC bond formation; N-heterocyclic carbenes; aryl ketones; nickel