Pneumonia and bacteremia in a golden-headed lion tamarin (Leontopithecus chrysomelas) caused by Klebsiella pneumoniae subsp. pneumoniae during a translocation program of free-ranging animals in Brazil.
Klebsiella pneumoniae is an important emerging pathogen in humans, particularly the invasive hypermucoviscosity (HMV) phenotype. In addition, the organism is an important public health concern because of nosocomial infections and antimicrobial resistance. Nonhuman primates in captivity are susceptible to Klebsiella, particularly when a stress factor is involved. Infections vary depending on the species but can cause significant morbidity and mortality in these animals. The objective of this study was to describe a case of bronchopneumonia and bacteremia caused by Klebsiella pneumoniae in a free-ranging golden-headed lion tamarin (Leontopithecus chrysomelas) caught and maintained in quarantine during a translocation program for conservation purposes. An adult male, that had showed emaciation and apathy, was clinically examined and, despite being provided supportive therapy, died 2 days after onset of clinical signs. At postmortem examination, generalized bilateral pneumonia and pericarditis were observed. Tissue samples were fixed in 10% formalin for histology, and pulmonary tissues and cardiac blood were collected for microbiologic diagnostic procedures. Bacteria that were shown to be HMV K. pneumoniae subsp. pneumoniae strains were isolated from the pulmonary fluids and cardiac blood in pure cultures. Severe bronchopneumonia was the main pathological finding. The consequences of the confirmed presence of the HMV phenotype of K. pneumoniae subsp. pneumoniae in this wildlife species for human, animal, and ecosystem health should be determined. These results demonstrate the importance of quarantine and potential pathogen screening during wildlife translocation procedures.
Pri-Matas for Biodiversity Conservation Institute, Belo Horizonte, Brazil (Bueno, Kierulff)Molecular and Cell Biology Laboratory, Institute of Health Sciences, Paulista University, São Paulo, Brazil (Iovine)Laboratory of Wildlife Comparative Pathology, LAPCOM, School of Veterinary Medicine and Animal Sciences, Pathology Department, São Paulo University, São Paulo, Brazil (Torres, Catão-Dias, Carvalho)Rio de Janeiro Primatology Center-CPRJ/INEA and Serra dos Órgãos University-UNIFESO, Rio de Janeiro, Brazil (Pissinatti)Post-Graduation Program for Tropical Biodiversity, Federal University of Espírito Santo, São Mateus, Espírito Santo, Brazil (Kierulff) buenomg@gmail.com.
Marina G
MG
Bueno
Pri-Matas for Biodiversity Conservation Institute, Belo Horizonte, Brazil (Bueno, Kierulff)Molecular and Cell Biology Laboratory, Institute of Health Sciences, Paulista University, São Paulo, Brazil (Iovine)Laboratory of Wildlife Comparative Pathology, LAPCOM, School of Veterinary Medicine and Animal Sciences, Pathology Department, São Paulo University, São Paulo, Brazil (Torres, Catão-Dias, Carvalho)Rio de Janeiro Primatology Center-CPRJ/INEA and Serra dos Órgãos University-UNIFESO, Rio de Janeiro, Brazil (Pissinatti)Post-Graduation Program for Tropical Biodiversity, Federal University of Espírito Santo, São Mateus, Espírito Santo, Brazil (Kierulff).
Renata O
RO
Iovine
Pri-Matas for Biodiversity Conservation Institute, Belo Horizonte, Brazil (Bueno, Kierulff)Molecular and Cell Biology Laboratory, Institute of Health Sciences, Paulista University, São Paulo, Brazil (Iovine)Laboratory of Wildlife Comparative Pathology, LAPCOM, School of Veterinary Medicine and Animal Sciences, Pathology Department, São Paulo University, São Paulo, Brazil (Torres, Catão-Dias, Carvalho)Rio de Janeiro Primatology Center-CPRJ/INEA and Serra dos Órgãos University-UNIFESO, Rio de Janeiro, Brazil (Pissinatti)Post-Graduation Program for Tropical Biodiversity, Federal University of Espírito Santo, São Mateus, Espírito Santo, Brazil (Kierulff).
Luciana N
LN
Torres
Pri-Matas for Biodiversity Conservation Institute, Belo Horizonte, Brazil (Bueno, Kierulff)Molecular and Cell Biology Laboratory, Institute of Health Sciences, Paulista University, São Paulo, Brazil (Iovine)Laboratory of Wildlife Comparative Pathology, LAPCOM, School of Veterinary Medicine and Animal Sciences, Pathology Department, São Paulo University, São Paulo, Brazil (Torres, Catão-Dias, Carvalho)Rio de Janeiro Primatology Center-CPRJ/INEA and Serra dos Órgãos University-UNIFESO, Rio de Janeiro, Brazil (Pissinatti)Post-Graduation Program for Tropical Biodiversity, Federal University of Espírito Santo, São Mateus, Espírito Santo, Brazil (Kierulff).
José L
JL
Catão-Dias
Pri-Matas for Biodiversity Conservation Institute, Belo Horizonte, Brazil (Bueno, Kierulff)Molecular and Cell Biology Laboratory, Institute of Health Sciences, Paulista University, São Paulo, Brazil (Iovine)Laboratory of Wildlife Comparative Pathology, LAPCOM, School of Veterinary Medicine and Animal Sciences, Pathology Department, São Paulo University, São Paulo, Brazil (Torres, Catão-Dias, Carvalho)Rio de Janeiro Primatology Center-CPRJ/INEA and Serra dos Órgãos University-UNIFESO, Rio de Janeiro, Brazil (Pissinatti)Post-Graduation Program for Tropical Biodiversity, Federal University of Espírito Santo, São Mateus, Espírito Santo, Brazil (Kierulff).
Alcides
A
Pissinatti
Pri-Matas for Biodiversity Conservation Institute, Belo Horizonte, Brazil (Bueno, Kierulff)Molecular and Cell Biology Laboratory, Institute of Health Sciences, Paulista University, São Paulo, Brazil (Iovine)Laboratory of Wildlife Comparative Pathology, LAPCOM, School of Veterinary Medicine and Animal Sciences, Pathology Department, São Paulo University, São Paulo, Brazil (Torres, Catão-Dias, Carvalho)Rio de Janeiro Primatology Center-CPRJ/INEA and Serra dos Órgãos University-UNIFESO, Rio de Janeiro, Brazil (Pissinatti)Post-Graduation Program for Tropical Biodiversity, Federal University of Espírito Santo, São Mateus, Espírito Santo, Brazil (Kierulff).
Maria C M
MC
Kierulff
Pri-Matas for Biodiversity Conservation Institute, Belo Horizonte, Brazil (Bueno, Kierulff)Molecular and Cell Biology Laboratory, Institute of Health Sciences, Paulista University, São Paulo, Brazil (Iovine)Laboratory of Wildlife Comparative Pathology, LAPCOM, School of Veterinary Medicine and Animal Sciences, Pathology Department, São Paulo University, São Paulo, Brazil (Torres, Catão-Dias, Carvalho)Rio de Janeiro Primatology Center-CPRJ/INEA and Serra dos Órgãos University-UNIFESO, Rio de Janeiro, Brazil (Pissinatti)Post-Graduation Program for Tropical Biodiversity, Federal University of Espírito Santo, São Mateus, Espírito Santo, Brazil (Kierulff).
Vania M
VM
Carvalho
D000818:Animals; D000835:Animals, Wild; D016470:Bacteremia / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D001938:Brazil; D003428:Cross Infection; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D007711:Klebsiella pneumoniae / Q000302:isolation & purification*; D051039:Leontopithecus; D008297:Male; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*
Hypermucoviscosity phenotype; Klebsiella pneumoniae; Leontopithecus chrysomelas; translocation