Two new isoflavanones from the roots of Erythrina variegata.
Two new isoflavanones, eryvarins Y (1) and Z (2), together with three known compounds (3-5) were isolated from the roots of Erythrina variegata. The structures of 1 and.2 were established on the basis of spectroscopic data. The new compounds are peculiar isoflavanones, possessing both a 3-methylbut-2-en- 1-yl group and a 2-hydroxy-3-methylbut-3-en-1-yl group. Among the isolates, orientanol E (5) exhibited potent antibacterial activity against methicillin- resistant Staphylococcus aureus (MRSA) strains.
Hitoshi
H
Tanaka
Ikunori
I
Atsumi
Motori
M
Hasegawa
Miyuki
M
Hirata
Tatsuko
T
Sakai
Masaru
M
Sato
Ryozo
R
Yamaguchi
Yoichi
Y
Tateishi
Toshiyuki
T
Tanaka
Toshio
T
Fukai
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004895:Erythrina / Q000737:chemistry*; D007529:Isoflavones / Q000737:chemistry* / Q000494:pharmacology; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D007529:Isoflavones; C000598502:eryvarin Y; C000598503:eryvarin Z