[Successful treatment of cutaneous leishmaniasis with amphotericin B; a case of unresponsive to pentavalent antimony therapy].
Cutaneous Leishmaniasis (CL) is a skin infection caused by various species of Leishmania parasites, which is transmitted by infected Phlebotomus sandfly bites. Pentavalent antimonials (meglumine antimoniate and sodium stibogluconate) are used for the treatment of adult CL patients as an effective and safe method. Liposomal amphotericin B is an alternative for the treatment of choice in cutaneous leishmaniasis cases which pentavalan antimony contraindicated or unresponsive to pentavalent antimony therapy. In this study, successful treatment with systemic liposomal amphotericin B of a cutaneous leishmaniasis case developing local side effects related both systemic and intralesional meglumine antimonate treatment was presented.
Harran Üniversitesi Tıp Fakültesi, Dermatoloji Anabilim Dalı, Şanlıurfa, Türkiye. yavuzyesilova@gmail.com.
Yavuz
Y
Yeşilova
Enver
E
Turan
Hacer Altın
HA
Sürücü
Mustafa
M
Aksoy
Ahmet
A
Özbilgin
D061605:Administration, Intravenous; D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D000981:Antiprotozoal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D007273:Injections, Intramuscular; D007299:Insect Bites and Stings / Q000150:complications; D007303:Insect Vectors / Q000469:parasitology; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy* / Q000635:transmission; D008536:Meglumine / Q000627:therapeutic use; D000077485:Meglumine Antimoniate; D009942:Organometallic Compounds / Q000627:therapeutic use; D010691:Phlebotomus / Q000469:parasitology
D000981:Antiprotozoal Agents; D009942:Organometallic Compounds; C068538:liposomal amphotericin B; D008536:Meglumine; D000077485:Meglumine Antimoniate; D000666:Amphotericin B