Long Term Treatment Results for Deep Infections of Total Knee Arthroplasty.
This study aims to identify the long-term outcomes of total knee arthroplasty (TKA) treated for deep infection. 3270 consecutive primary and 175 revision TKAs were followed prospectively. There were 39 deep infections (1.16%): 29 primary (0.9%) and 10 revision (5.7%) cases. Two-stage resection and re-implantation procedure was performed in 13 primary cases with 10/13 (77%) successfully resolved. Early (<1 month) Irrigation and Debridement (I&D) was performed in 16 primary cases with 100% success. Late (>4 months) I&D was performed in 6 cases with 5/6 (83.3%) successful. Infection following revision TKA resulted in poor outcomes with both two-stage (2/4 successful) and I&D (2/6 successful). Deep infection after primary TKA can be successfully resolved with I&D and appropriate antibiotic treatment in the early postoperative course.
Holy Cross Hospital Orthopaedic Institue, Fort Lauderdale, Florida.
Kevin H
KH
Wang
New York University Langone Medical Center/Hospital for Joint Diseases, New York, New York.
Stephen W
SW
Yu
New York University Langone Medical Center/Hospital for Joint Diseases, New York, New York.
Richard
R
Iorio
Department of Orthopaedic Surgery, Lahey Clinic Medical Center, Burlington, Massachusetts.
Andrew J
AJ
Marcantonio
Department of Orthopaedic Surgery, Lahey Clinic Medical Center, Burlington, Massachusetts.
Michael S
MS
Kain
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects* / Q000379:methods*; D001424:Bacterial Infections / Q000188:drug therapy / Q000601:surgery; D003646:Debridement / Q000379:methods; D048909:Diabetes Complications / Q000175:diagnosis; D006801:Humans; D007720:Knee Prosthesis; D011446:Prospective Studies; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000601:surgery*; D012086:Reoperation; D012092:Replantation / Q000379:methods*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents
irrigation and debridement; long term outcomes; peri-prosthetic joint infection; revision knee arthroplasty; timing; two stage revision