Using fibers for rapid extraction of proteins from urine.
The method for rapid extraction of proteins from urine published in this special issue (Manard, B. T. et al., Proteomics Clin. Appl. 2015, 9, 522-530) may have more profound implications than the authors have claimed, simply because urine is more important than most biomarker researchers realized. Unlike blood that is tightly controlled by homeostatic mechanisms of the body, urine tolerates, and accumulates a much larger degree of changes in its components, making it a more important biomarker source than blood.
Beijing Normal University, Beijing, P. R. China.
Youhe
Y
Gao
D006801:Humans; D011507:Proteinuria / Q000652:urine*; D020543:Proteome / Q000302:isolation & purification*; D016482:Urinalysis / Q000379:methods*
D020543:Proteome
Fiber; Solid phase extraction; Storage; Urinary proteins