Corneal Viscoelastic Properties in Patients with Angioid Streaks.
OBJECTIVE
The aim of this study is to investigate the possible corneal biomechanical changes in patients with angioid streaks and to understand if the calcified and thickened Bruch's membrane associated with angioid streaks influences elasticity of the eye and intraocular pressure.


METHODS
Twelve eyes of 12 patients with angioid streaks (six males and six females) and 12 eyes of 12 age- and sex-matched healthy volunteers were enrolled in the study. Corneal hysteresis (CH), corneal resistance factor (CRF), corneal compensated intraocular pressure (IOPcc) and Goldmann-correlated intraocular pressure (IOPg) were measured with an Ocular Response Analyzer (ORA). Central corneal thickness (CCT) was measured with an ultrasound pachymeter.


RESULTS
Mean CRF and IOPg values in eyes with angioid streaks (12.10 ± 1.27 and 17.76 ± 2.73, respectively) were significantly higher than those in matched control eyes (10.70 ± 1.28 and 14.67 ± 2.72, respectively; p = 0.01 for CRF, p = 0.007 for IOPg). There was no statistically significant difference between eyes with angioid streaks and matched control eyes in measured CH, IOPcc and CCT values (p = 0.29, p = 0.09 and p = 0.86, respectively).


CONCLUSIONS
This study revealed that angioid streaks can affect corneal biomechanical properties by increasing CRF, as compared to the healthy eyes. Increased CRF means increased resistance for effect of IOP on eye so it can be speculated that these patients tend to be more protected for glaucoma.
a Department of Ophthalmology, Cerrahpasa Medical Faculty , Istanbul University , Istanbul , Turkey and.
Rengin
R
Yildirim
b Department of Ophthalmology , Derik State Hospital , Mardin , Turkey.
Funda
F
Dikkaya
a Department of Ophthalmology, Cerrahpasa Medical Faculty , Istanbul University , Istanbul , Turkey and.
Ceyhun
C
Arici
a Department of Ophthalmology, Cerrahpasa Medical Faculty , Istanbul University , Istanbul , Turkey and.
Didar Ucar
DU
Comlekoglu
D000328:Adult; D000793:Angioid Streaks / Q000175:diagnosis / Q000503:physiopathology*; D001696:Biomechanical Phenomena / Q000502:physiology; D016570:Bruch Membrane / Q000503:physiopathology; D003315:Cornea / Q000502:physiology*; D063171:Corneal Pachymetry; D004548:Elasticity / Q000502:physiology*; D005260:Female; D005451:Fluorescein Angiography; D064368:Healthy Volunteers; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014065:Tonometry, Ocular
Angioid streaks; corneal hysteresis; corneal resistance factor; corneal viscoelastic properties; intraocular pressure