Drug delivery technologies and stem cells for tissue repair and regeneration.
In the last few years several technologies are being developed for eventually repairing or replacing damaged or injured tissues and even organs. Some of these emerging technologies include the design and development of new biomaterials, the optimization of nano- and micro-technologies for drug and cell delivery, the use of autologous proteins or the application of stem cells as therapeutics. Thus, several types of stem cells, e.g. ESCs, iPSCs, MSCs, CD133+ stem cells are being evaluated for tissue regeneration purposes. The present review describes some of these emerging technologies and discusses their potential benefits and challenges.
Laboratory of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of the Basque Country, Vitoria, Spain. gorka.orive@ehu.es.
Gorka
G
Orive
Raquel
R
Cobos
Janire
J
Gorriti
Jose L
JL
Pedraz
Mirella
M
Meregalli
Yvan
Y
Torrente
D000818:Animals; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D012038:Regeneration / Q000187:drug effects* / Q000502:physiology; D044968:Regenerative Medicine / Q000379:methods / Q000639:trends; D033581:Stem Cell Transplantation / Q000379:methods*; D013234:Stem Cells / Q000502:physiology; D014945:Wound Healing / Q000187:drug effects* / Q000502:physiology