Successful treatment of treatment-resistant schizophrenia in a 10-year-catatonic patient by augmentation of selective serotonin reuptake inhibitors: a case report.
Although catatonia is a well defined syndrome, the treatment of chronic catatonia remains an unresolved issue. Here, we report a successful treatment of a 30-year-old patient with treatment-resistant catatonic schizophrenia in 10 years by augmentation of selective serotonin reuptake inhibitors (SSRIs).We present a 30-year-old man with treatment-resistant catatonic schizophrenia who failed to respond to the treatment of benzodiazepines and antipsychotics for 10 years. He markedly improved after taking SSRIs. Now, he does not hold odd postures and begins to talk and show more facial expressions.We postulate that the therapeutic effect is related to the enhancement of 5-HT neurotransmission. SSRIs can be a considerable choice to treat chronic catatonia.
From the Department of Psychiatry, Taichung Veterans General Hospital (M-JC, K-DJ, C-HC); Master of Psychology, Kaohsiung Medical University (M-JC); Department of Psychiatry, Chiayi Branch, Taichung Veterans General Hospital (S-SH); School of Medicine, Chung Shan Medical University (S-SH); Faculty of Medicine, National Yang Ming University (S-SH, K-DJ); Candidate of Master of Epidemics, National Taiwan University, Taiwan, ROC (S-SH); Master of Arts, University of Chicago, Illinois, USA (K-DJ); National Defense Medical Center, Taiwan, ROC (C-HC); Master of Administrative Medicine, University of Wisconsin, Wisconsin, USA (C-HC).
Mei-Jung
MJ
Chen
Shiau-Shian
SS
Huang
Kai-Dih
KD
Juang
Chin-Hong
CH
Chan
D000328:Adult; D002389:Catatonia / Q000188:drug therapy*; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000188:drug therapy*; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*
D017367:Selective Serotonin Reuptake Inhibitors