Silver(I) NHC mediated C-C bond activation of alkyl nitriles and catalytic efficiency in oxazoline synthesis.
Preparation of silver triazolylidene (trz) species from triazolium salts and Ag2O in refluxing MeCN leads to a selective C-C bond cleavage and the formation of complexes of general formula [(trz)Ag(CN)] from Calkyl-CN bond activation. Moreover, these silver carbene complexes are precursors of highly active catalysts for oxazoline formation via aldol condensation.
School of Chemistry & Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland. martin.albrecht@ucd.ie.
Rachael
R
Heath
Helge
H
Müller-Bunz
Martin
M
Albrecht