Sex differences in the association between body mass index and hypertension - a cross-sectional study in 717 812 adolescents.
In order to examine sex-specific differences in the association of body mass index (BMI) and hypertension, we conducted a retrospective, cross-sectional study of 717 812 (402 914 men and 314 898 women) Israeli Jewish adolescents aged 16.0-19.99 years medically screened for military service. A diagnosis of hypertension was established per history or if a mean of 10 separate blood pressure measurements exceeded 140/90, following an initial measurement higher than 140/90. Weight and height were measured. Prevalence of hypertension was 0.42% in men and 0.05% in women. In men, BMI was significantly associated with hypertension from the third decile (odds ratio [OR] 1.67, 1.06-2.65) up to the 10th decile (OR 30.17, 20.83-43.69). In women, we observed a significantly increased risk for hypertension in the ninth decile (OR 3.82, 1.42-10.22) and in the 10th decile (OR 18.92, 7.7-46.51), with no visible trend in lower deciles. BMI effects on hypertension prevalence are different in male and female adolescents.
Israeli Defense Force Medical Corps, Tel Hashomer, Israel.|The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Gordon
The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.|The Chaim Sheba Medical Center, Ramat Gan, Israel.
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Shamiss
The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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E
Derazne
Israeli Defense Force Medical Corps, Tel Hashomer, Israel.
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Tzur
The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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Afek
D000293:Adolescent; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D001835:Body Weight; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D007557:Israel; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D055815:Young Adult
Adolescents; body mass index; hypertension; sex