Preoperative and intraoperative prognostic factors of epiretinal membranes using chromovitrectomy and internal limiting membrane peeling.
OBJECTIVE
To evaluate the preoperative and intraoperative findings as prognostic indicators of functional and anatomic results of idiopathic epiretinal membrane (ERM) surgery.


METHODS
Vitrectomies included ERM and internal limiting membrane (ILM) removal with vital dyes. Best corrected visual acuity (BCVA), optical coherence tomography (OCT), fluorescein angiography, and autofluorescence were performed at baseline and postoperatively. Intraoperative ILM status after ERM removal was also evaluated.


RESULTS
Thirty-one eyes were monitored for a mean of 16.78 months. BCVA and central foveal thickness (CFT) improved significantly (P < .001) from baseline at 3 and 12 months. Preoperative hyperautofluorescence was associated with greater CFT reduction (P < .005). ILM status after ERM peeling did not influence visual recovery but was associated with anatomical results as measured by OCT.


CONCLUSIONS
Preoperative poor initial BCVA and RPE defects by FAF may not be bad prognostic factors. Preoperative hyperautofluorescence was associated with greater CFT reduction. Intraoperative classification of ILM status after ERM and ILM staining/peeling was reported and may be useful for future studies, though it was not associated neither with preoperative nor postoperative BCVA.
Leonardo M
LM
Machado
Bruno A
BA
Furlani
Rodrigo M
RM
Navarro
Michel E
ME
Farah
Andre
A
Maia
Octaviano
O
Magalhães
Eduardo B
EB
Rodrigues
Nilva
N
Moraes
Mauricio
M
Maia
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001485:Basement Membrane / Q000473:pathology / Q000601:surgery*; D002863:Chromogenic Compounds; D019773:Epiretinal Membrane / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D061848:Optical Imaging; D011183:Postoperative Complications; D011184:Postoperative Period; D057234:Preoperative Period; D011379:Prognosis; D012189:Retrospective Studies; D012394:Rosaniline Dyes; D041623:Tomography, Optical Coherence; D014222:Triamcinolone Acetonide; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy / Q000379:methods*; D014822:Vitreous Body / Q000473:pathology
D002863:Chromogenic Compounds; D012394:Rosaniline Dyes; D014222:Triamcinolone Acetonide; C004692:coomassie Brilliant Blue