Disseminated cat-scratch disease: case report and review of the literature.
Cat scratch disease (CSD) can present as a systemic disease in 5-10% of cases and lead to various disease entities. A previously healthy 16-month-old boy presented with fever for 7 days without other obvious symptoms. Abdominal computed tomography scan demonstrated enlarged right inguinal lymph nodes and multiple small round hypodensities in the spleen. Despite antibiotic treatment for 1 week, the fever persisted and the intrasplenic lesions progressed. Inguinal lymph node biopsy confirmed CSD by immunohistochemistry staining. The diagnosis of CSD was also supported by a history of contact, imaging and serological findings. The patient recovered after treatment with azithromycin for a total of 5 weeks and, in serial follow-up, the hepatosplenic micro-abscesses resolved after 4th months.
a Department of Medical Imaging and Intervention , Chang Gung Memorial Hospital , Linkou , Taiwan.
Chih-Chen
CC
Chang
b Department of Pediatrics , Chang Gung Memorial Hospital , Linkou , Taiwan.
Chia-Jie
CJ
Lee
c Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics , Chang Gung Memorial Hospital , Linkou , Taiwan.
Liang-Shiou
LS
Ou
a Department of Medical Imaging and Intervention , Chang Gung Memorial Hospital , Linkou , Taiwan.
Chao-Jan
CJ
Wang
b Department of Pediatrics , Chang Gung Memorial Hospital , Linkou , Taiwan.|d Chang Gung University College of Medicine , Kweishan, Taoyuan , Taiwan.
Yhu-Chering
YC
Huang
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use*; D018416:Bartonella henselae / Q000302:isolation & purification*; D001706:Biopsy; D002372:Cat-Scratch Disease / Q000175:diagnosis* / Q000188:drug therapy; D002415:Cats; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents; D017963:Azithromycin
Bartonella henselae; Cat scratch disease; Immunohistochemistry stain; Splenic abscess