Efficient intracellular delivery and improved biocompatibility of colloidal silver nanoparticles towards intracellular SERS immuno-sensing.
High throughput intracellular delivery strategies, electroporation, passive and TATHA2 facilitated diffusion of colloidal silver nanoparticles (AgNPs) are investigated for cellular toxicity and uptake using state-of-art analytical techniques. The TATHA2 facilitated approach efficiently delivered high payload with no toxicity, pre-requisites for intracellular applications of plasmonic metal nanoparticles (PMNPs) in sensing and therapeutics.
10555 West Flagler Street, Department of Biomedical Engineering, Florida International University, Miami, FL, USA. mcgorona@fiu.edu.
Vinay
V
Bhardwaj
Supriya
S
Srinivasan
Anthony J
AJ
McGoron
D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism; D001692:Biological Transport; D015374:Biosensing Techniques; D018274:Electroporation; D007118:Immunoassay; D042541:Intracellular Space / Q000378:metabolism*; D053758:Nanoparticles; D010455:Peptides / Q000737:chemistry*; D012834:Silver / Q000737:chemistry* / Q000378:metabolism*
D001672:Biocompatible Materials; D010455:Peptides; C586932:colloidal silver; D012834:Silver