Continuous Positive Airway Pressure treatment of premature infants; application of a computerized decision support system.
The predictions of a computerized decision-support system (CDSS) are compared to clinical data obtained from a group of premature infants. The infants were suffering from respiratory distress syndrome (RDS) and were treated by the Continuous Positive Airway Pressure (CPAP) therapy. The predictions of the CDSS are found to be in general agreement with clinical measurements. The CDSS is also used to determine the effect of low level oxygen treatment on arterial oxygen pressure if the infant׳s oxygenation is low despite CPAP therapy. Based on the computational results, application of low levels of supplemental inspired fraction of oxygen ( [Formula: see text] ) would result in significant improvement in oxygenation of premature infants provided such treatment is carefully controlled to avoid hyperoxemia.
Department of Electrical Engineering, California State University, Fullerton, 800N. State College Boulevard, Fullerton, CA 92831, USA. Electronic address: ftehrani@fullerton.edu.
Fleur T
FT
Tehrani
University of Pennsylvania School of Medicine, Philadelphia, PA 19107, USA. Electronic address: Soraya.abbasi@uphs.upenn.edu.
Soraya
S
Abbasi
D045422:Continuous Positive Airway Pressure / Q000295:instrumentation* / Q000379:methods*; D003658:Decision Making, Computer-Assisted; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*
Computerized decision-support systems; Continuous Positive Airway Pressure; Oxygen; Premature infants; Respiratory distress syndrome