Comparison of field-of-view (FOV) optimized and constrained undistorted single shot (FOCUS) with conventional DWI for the evaluation of prostate cancer.
OBJECTIVE
Qualitative and quantitative comparison of the application value of diffusion-weighted imaging (DWI) magnetic resonance imaging based on field-of-view (FOV) optimized and constrained undistorted single shot (FOCUS) with the standard single-shot echo-planar imaging (ss-EPI) in patients with prostate cancer.


METHODS
A total of 28 patients with 33 prostate cancers underwent ss-EPI and FOCUS DWI. Two independent readers assessed image studies.


RESULTS
Image qualities of FOCUS were rated superior to ss-EPI (P<.001). The mean apparent diffusion coefficient value of 33 cancers was 974.030×10(-6)mm(2)/s and 941.727×10(-6)mm(2)/s, respectively, and the difference was statistically significant (t=2.579, P=.015).


CONCLUSIONS
FOCUS as a high-resolution DWI technique has potential clinical utility.
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Zhaoyan
Z
Feng
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Xiangde
X
Min
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Vivek Kumar
VK
Sah
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Liang
L
Li
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Jie
J
Cai
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.
Ming
M
Deng
Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China. Electronic address: wang6@tjh.tjmu.edu.cn.
Liang
L
Wang
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D017352:Echo-Planar Imaging / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000175:diagnosis*
Apparent diffusion coefficient; Diffusion-weighted magnetic resonance imaging; Echo-planar imaging; Prostate cancer