Attitudes and Knowledge of Maternal-Fetal Medicine Fellows Regarding Noninvasive Prenatal Testing.
Using cell-free DNA in maternal serum to detect fetal aneuploidy has been shown to have high sensitivity and specificity. The purpose of this study was to assess attitudes and knowledge of Maternal-Fetal Medicine (MFM) fellows regarding noninvasive prenatal testing (NIPT). A 13 question survey was sent via listserv to US-based MFM fellows. One hundred sixteen fellows responded, a 42.3% response rate, with >75% reporting they are comfortable ordering NIPT. Most (82%) preferred that a patient discuss options with a provider or genetic counselor. Three common methods used to learn about NIPT were: formal educational activities (n = 78, 69%), self-review of the literature (n = 76, 67%), and discussions with peers (n = 73, 65%). On questions related to trisomy 21, accuracy was >70%. However, accuracy was lower regarding use in twin pregnancies (42%) and monosomy X screening (50%).
New Hanover Regional Medical Center, Wilmington, NC, USA.|University of North Carolina - Chapel Hill, 3010 Old Clinic Building, CB 7516, Chapel Hill, NC, 27516, USA.
Paul
P
Swaney
University of North Carolina - Chapel Hill, 3010 Old Clinic Building, CB 7516, Chapel Hill, NC, 27516, USA.
Emily
E
Hardisty
Duke University, Durham, NC, 27708, USA.
Lauren
L
Sayres
University of North Carolina - Chapel Hill, 3010 Old Clinic Building, CB 7516, Chapel Hill, NC, 27516, USA.
Samantha
S
Wiegand
University of North Carolina - Chapel Hill, 3010 Old Clinic Building, CB 7516, Chapel Hill, NC, 27516, USA. neetavora@gmail.com.
Neeta
N
Vora
D000328:Adult; D000782:Aneuploidy; D001291:Attitude of Health Personnel; D005260:Female; D005820:Genetic Testing / Q000379:methods; D006801:Humans; D062145:Maternal Serum Screening Tests; D008875:Middle Aged; D011296:Prenatal Diagnosis / Q000379:methods*; D018570:Risk Assessment
Attitudes; Cell free fetal DNA; Education; Knowledge; Noninvasive prenatal testing