Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy.
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.). Elizabeth.mcnally@northwestern.edu kaltmanj@nhlbi.nih.gov larry.markham@Vanderbilt.Edu.
Elizabeth M
EM
McNally
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.). Elizabeth.mcnally@northwestern.edu kaltmanj@nhlbi.nih.gov larry.markham@Vanderbilt.Edu.
Jonathan R
JR
Kaltman
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
D Woodrow
DW
Benson
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Charles E
CE
Canter
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Linda H
LH
Cripe
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Dongsheng
D
Duan
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Jonathan D
JD
Finder
William J
WJ
Groh
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Eric P
EP
Hoffman
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Daniel P
DP
Judge
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Naomi
N
Kertesz
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Kathi
K
Kinnett
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Roxanne
R
Kirsch
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Joseph M
JM
Metzger
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Gail D
GD
Pearson
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Jill A
JA
Rafael-Fortney
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Subha V
SV
Raman
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Christopher F
CF
Spurney
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Shari L
SL
Targum
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.).
Kathryn R
KR
Wagner
From Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (E.M.M.); Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD (J.R.K., G.D.P.); Division of Cardiology, Children's Hospital of Wisconsin, Milwaukee (D.W.B.); Department of Pediatrics, Washington University, St. Louis, MO (C.E.C.); The Heart Center, Nationwide Children's Hospital, Columbus, OH (L.H.C., N.K.); Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia (D.D.); Division of Pulmonary Medicine, Children's Hospital of Pittsburgh, PA (J.D.F.); Center for Genetic Medicine Research (E.P.H.) and Division of Cardiology, Children's National Heart Institute, Center for Genetic Medicine Research (C.F.S.), Children's National Health System, Washington, DC; Division of Cardiology, Johns Hopkins School of Medicine, Baltimore, MD (D.P.J.); Parent Project Muscular Dystrophy, Middletown, OH (K.K.); Division of Cardiac Critical Care, Children's Hospital of Philadelphia, PA (R.K.); Department of Integrative Biology and Physiology, University of Minnesota Medical School, Minneapolis (J.M.M.); Department of Molecular and Cellular Biochemistry (J.A.R.-F.) and Division of Cardiovascular Medicine (S.V.R.), Ohio State University, Columbus; Division of Cardiovascular and Renal Products, US Food and Drug Administration, Silver Spring, MD (S.L.T.); Hugo W. Moser Research Institute, Kennedy Krieger Institute, Baltimore, MD (K.R.W.); and Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN (L.W.M.). Elizabeth.mcnally@northwestern.edu kaltmanj@nhlbi.nih.gov larry.markham@Vanderbilt.Edu.
Larry W
LW
Markham
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000209:etiology; D018070:Biological Specimen Banks / Q000458:organization & administration; D002311:Cardiomyopathy, Dilated / Q000188:drug therapy / Q000209:etiology* / Q000628:therapy; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D003935:Diagnostic Techniques, Cardiovascular; D004195:Disease Models, Animal; D005838:Genotype; D005938:Glucocorticoids / Q000627:therapeutic use; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D020388:Muscular Dystrophy, Duchenne / Q000150:complications* / Q000235:genetics; D010641:Phenotype; D012042:Registries; D012120:Respiration Disorders / Q000209:etiology / Q000628:therapy; D012121:Respiration, Artificial; D018487:Ventricular Dysfunction, Left / Q000188:drug therapy / Q000209:etiology / Q000628:therapy
D000806:Angiotensin-Converting Enzyme Inhibitors; D005938:Glucocorticoids
cardiomyopathy; dystrophin; heart failure; magnetic resonance imaging; muscular dystrophy