Solid state structure of p-bromo phenyl 4,5,7-tri-O-benzyl-β-D-glycero-D-talo-septanoside and an analysis of non-covalent interactions.
The solid state structure of a new seven-membered sugar oxepane derivative, namely, p-bromo phenyl 4,5,7-tri-O-benzyl-β-D-glycero-D-talo-septanoside is discussed, as determined through single crystal X-ray structural determination and in relation to their conformational features. The molecule adopts twist-chair as the preferred conformation, with conformational descriptor (O,1)TC(2,3). The solid state packing of molecules is governed by a rich network of non-covalent bonding originating from O-H⋯O, C-H⋯π, C-H⋯Br and aromatic π⋯π interactions that stabilize the packing of molecules in the crystal.
Department of Organic Chemistry, Indian Institute of Science, Bangalore 560012, India.
Supriya
S
Dey
Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560012, India.
Krishnayan
K
Basuroy
Department of Organic Chemistry, Indian Institute of Science, Bangalore 560012, India. Electronic address: jayaraman@orgchem.iisc.ernet.in.
N
N
Jayaraman
D018360:Crystallography, X-Ray; D008689:Methacrylates / Q000737:chemistry*; D008968:Molecular Conformation; D009943:Organophosphorus Compounds / Q000737:chemistry*; D010082:Oxepins / Q000737:chemistry*; D060327:Solid-Phase Synthesis Techniques; D013402:Sugar Alcohols / Q000737:chemistry*
D008689:Methacrylates; D009943:Organophosphorus Compounds; D010082:Oxepins; C074232:Phenyl-P adhesion promoting monomer; D013402:Sugar Alcohols; C000604395:p-bromo phenyl 4,5,7-tri-O-benzyl-beta-D-glycero-D-talo-septanoside
Carbohydrates; Conformations; Crystallography; Non-covalent interactions; Oxepanes; Septanosides