Precision medicine: Clarity for the clinical and biological complexity of Alzheimer's and Parkinson's diseases.
The goal of precision medicine is to deliver optimally targeted and timed interventions tailored to an individual's molecular drivers of disease. This concept has wide currency in cancer care and in some diseases caused by monogenetic mutations, such as cystic fibrosis, and recently has been endorsed by the White House Office of Science and Technology for more widespread application in medicine. Here we describe our vision of how precision medicine can bring greater clarity to the clinical and biological complexity of the two most common neurodegenerative diseases, Alzheimer's disease and Parkinson's disease.
T.J. Montine and K.S. Montine are at the Department of Pathology, University of Washington, Seattle, WA 98104 tmontine@uw.edu.
Thomas J
TJ
Montine
T.J. Montine and K.S. Montine are at the Department of Pathology, University of Washington, Seattle, WA 98104 tmontine@uw.edu.
Kathleen S
KS
Montine
D000544:Alzheimer Disease / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D006801:Humans; D009154:Mutation; D010300:Parkinson Disease / Q000235:genetics / Q000473:pathology / Q000628:therapy*