The role of epigenomics in the neurodegeneration of ataxia-telangiectasia.
Key Laboratory of Animal Models & Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.
Jiali
J
Li
Dewei
D
Jiang
D000818:Animals; D001260:Ataxia Telangiectasia / Q000235:genetics* / Q000473:pathology; D044127:Epigenesis, Genetic; D006655:Histone Deacetylases / Q000378:metabolism; D006801:Humans; D051379:Mice; D009410:Nerve Degeneration / Q000201:enzymology / Q000235:genetics*; D009474:Neurons / Q000201:enzymology / Q000378:metabolism; D063151:Polycomb Repressive Complex 2 / Q000378:metabolism
D063151:Polycomb Repressive Complex 2; C498618:Hdac5 protein, mouse; D006655:Histone Deacetylases
EZH2; H3K27me3; HDAC4; ataxia-telangiectasia; cell cycle reentry; classic II HDACs; histone acetylation; histone methylation; neurodegenerative diseases; polycomb repressive complex 2