[Effect of Chemical Prevention Drugs-based MicroRNAs and Their Target Genes on Tumor Inhibition].
Chemopreventive drugs including natural chemopreventive drugs and synthetic chemopreventive drugs, it not only can prevent cancer, can also play a role in tumor treatment. MicroRNAs (miRNAs) is a kind of short chains of non-coding RNA, regulating the expression of many genes through the way of degradation of mRNA or inhibitting mRNA translation. In recent years, more and more studies have shown that chemopreventive drugs through influence the expression of miRNAs and their target genes play a role in the prevention and treatment in a variety of tumors, and chemopreventive drugs on the experimental study of miRNAs and their target genes in tumor have demonstrated a good safety and efficacy. Effect on chemopreventive drugs-based microRNAs and their target genes into cancer cells will be expected as a new starting point for cancer research. The thesis expounds and analyzes between the natural chemopreventive drugs and synthetic chemopreventive drugs and miRNAs and their target genes in tumor research progress.
Department of Cancer Biotherapy Center, the Third Affiliated Hospital of Kunming Medical University, Kunming 650118, China.
Yanhui
Y
Jiang
Department of Cancer Biotherapy Center, the Third Affiliated Hospital of Kunming Medical University, Kunming 650118, China.
Xin
X
Song
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D018890:Chemoprevention; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000378:metabolism / Q000517:prevention & control*; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism
D000970:Antineoplastic Agents; D035683:MicroRNAs