Evolution of septated cavitary subretinal fluid after treatment of choroidal metastasis.
An 83-year-old man presented with a 10-day history of decreased vision in the left eye. He was found to have choroidal metastases from lung adenocarcinoma that exhibited unilateral septated cavitary subretinal fluid on spectral-domain optical coherence tomography (OCT). This fluid evolved into atypical lamellar sheets after treatment with systemic chemotherapy and orbital radiation prior to resolution. This is the first description demonstrating cavitary subretinal fluid pockets on spectral-domain OCT from lung cancer; attention is given to its unusual course and proposed pathogenesis.
Austin L
AL
Strohbehn
Elliott H
EH
Sohn
D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary / Q000628:therapy*; D000369:Aged, 80 and over; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016190:Carboplatin / Q000627:therapeutic use; D002830:Choroid Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000628:therapy*; D003131:Combined Modality Therapy; D005110:Extracellular Space; D005451:Fluorescein Angiography; D005971:Glutamates / Q000627:therapeutic use; D006147:Guanine / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D008297:Male; D000068437:Pemetrexed; D011183:Postoperative Complications; D061766:Proton Therapy; D058471:Subretinal Fluid; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology
D000970:Antineoplastic Agents; D005971:Glutamates; D000068437:Pemetrexed; D006147:Guanine; D016190:Carboplatin