Functional MRI of the placenta--From rodents to humans.
The placenta performs a wide range of physiological functions; insufficiencies in these functions may result in a variety of severe prenatal and postnatal syndromes with long-term negative impacts on human adult health. Recent advances in magnetic resonance imaging (MRI) studies of placental function, in both animal models and humans, have contributed significantly to our understanding of placental structure, blood flow, oxygenation status, and metabolic profile, and have provided important insights into pregnancy complications.
Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
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Avni
Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address: michal.neeman@weizmann.ac.il.
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Neeman
Biomedical MR Laboratory, Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, United States. Electronic address: garbow@wustl.edu.
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Garbow
D000818:Animals; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010920:Placenta / Q000098:blood supply / Q000502:physiology* / Q000503:physiopathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000503:physiopathology
Functional imaging; MRI; Placenta; Preclinical models