Stress Relief Downstream of TOR.
Reduced activity of the growth-regulating TOR complex 1 induces transcription of many genes. In this issue of Developmental Cell, Tiebe et al. (2015) identify a transcriptional regulator complex repressed by TORC1 and responsible for a vast majority of the observed transcriptional changes in Drosophila.
Institute of Molecular Systems Biology, ETH Zürich, 8093 Zürich, Switzerland. Electronic address: stocker@imsb.biol.ethz.ch.
Hugo
H
Stocker
D000818:Animals; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000378:metabolism*; D006706:Homeostasis / Q000502:physiology*; D046912:Multiprotein Complexes / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*; D058570:TOR Serine-Threonine Kinases / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism*
D029721:Drosophila Proteins; D046912:Multiprotein Complexes; D014157:Transcription Factors; D058570:TOR Serine-Threonine Kinases