Cost-Effectiveness Analysis Comparing Pre-diagnosis Autism Spectrum Disorder (ASD)-Targeted Intervention with Ontario's Autism Intervention Program.
Novel management strategies for autism spectrum disorder (ASD) propose providing interventions before diagnosis. We performed a cost-effectiveness analysis comparing the costs and dependency-free life years (DFLYs) generated by pre-diagnosis intensive Early Start Denver Model (ESDM-I); pre-diagnosis parent-delivered ESDM (ESDM-PD); and the Ontario Status Quo (SQ). The analyses took government and societal perspectives to age 65. We assigned probabilities of Independent, Semi-dependent or Dependent living based on projected IQ. Costs per person (in Canadian dollars) were ascribed to each living setting. From a government perspective, the ESDM-PD produced an additional 0.17 DFLYs for $8600 less than SQ. From a societal perspective, the ESDM-I produced an additional 0.53 DFLYs for $45,000 less than SQ. Pre-diagnosis interventions targeting ASD symptoms warrant further investigation.
Autism Research Centre, Bloorview Research Institute, Holland Bloorview Kids Rehabilitation Hospital, 150 Kilgour Rd., Toronto, ON, M4G 1R8, Canada, mpenner@hollandbloorview.ca.
Melanie
M
Penner
Meera
M
Rayar
Naazish
N
Bashir
S Wendy
SW
Roberts
Rebecca L
RL
Hancock-Howard
Peter C
PC
Coyte
D000293:Adolescent; D000328:Adult; D001321:Autistic Disorder / Q000191:economics* / Q000534:rehabilitation; D001521:Behavior Therapy / Q000191:economics*; D003362:Cost-Benefit Analysis; D018479:Early Intervention, Educational / Q000191:economics*; D006801:Humans