Teflubenzuron as a tool for control of trichodinids in freshwater fish: Acute toxicity and in vivo efficacy.
In this study we describe the anti-Trichodina effects of teflubenzuron (TFB) for Oreochromis niloticus and for Piaractus mesopotamicus. We also evaluated the acute toxicity, for both species, by using TFB in the concentrations of 700.0, 800.0, 900.0 and 1000.0 mg L(-1) and a control, without the drug. To assess the efficacy of TFB against Trichodina spp., we used the concentrations of 30.0 or 50.0 mg L(-1) for one hour exposure in tilapia, and the concentration of 30.0, 50.0 and 80.0 mg L(-1) for one hour and 50 mg L(-1) for two hours exposures in pacu. Teflubenzuron did not present significant toxicity in either species, with LC50;48h > 1000.0 mg L(-1). The drug effectiveness was observed against four identified Trichodina species: T. magna, T. heterodentata, T. compacta and T. centrostrigeata, with 87.9% parasite reduction with one hour exposure to 50.0 mg L(-1) TFB on O. niloticus and 96.1% with two hours exposure to 50.0 mg L(-1) TFB on P. mesopotamicus. Teflubenzuron is a drug with potential to be used in Brazilian aquaculture; it attends to important requirements, such as low toxicity and high efficacy in controlling Trichodina spp. infection in O. niloticus and P. mesopotamicus.
Aquaculture Center, São Paulo State University (CAUNESP), Jaboticabal, SP, Brazil; Weed Science Environmental Research Studies, College of Agricultural and Veterinary Science at Unesp, Plant Health Department, São Paulo State University, Prof. Dr. Paulo Donato Castellani Access route, no number, rural area, CEP: 14884-900, Jaboticabal, SP, Brazil. Electronic address: cynthia.ikefuti@gmail.com.
Cynthia Venâncio
CV
Ikefuti
Weed Science Environmental Research Studies, College of Agricultural and Veterinary Science at Unesp, Plant Health Department, São Paulo State University, Prof. Dr. Paulo Donato Castellani Access route, no number, rural area, CEP: 14884-900, Jaboticabal, SP, Brazil.
Silvia Patrícia
SP
Carraschi
Weed Science Environmental Research Studies, College of Agricultural and Veterinary Science at Unesp, Plant Health Department, Graduate Program in Veterinary Pathology, São Paulo State University, Prof. Dr. Paulo Donato Castellani Access route, no number, rural area, CEP: 14884-900, Jaboticabal, SP, Brazil.
Roberto
R
Barbuio
University Center of Educational Foundation of Barretos (Unifeb), Professor Roberto Frade Monte Avenue, n° 389, CEP: 14783-226, Barretos, SP, Brazil.
Claudinei
C
da Cruz
AquiVet Aquatic Health, Cristóvão Colombo Street, 1519, Jardim Nazareth, CEP: 15054000, São José do Rio Preto, SP, Brazil.
Santiago Benites
SB
de Pádua
Fisheries Institute, Washington Luis Highway Km 445, Caixa Postal 1052, CEP: 15025-970, São José do Rio Preto, SP, Brazil.
Eduardo Makoto
EM
Onaka
Laboratory of Aquatic Organisms Pathology (CPDPO) Fisheries Institute, Francisco Matarazzo Avenue, n°455, Barra Funda, CEP: 05001-900, São Paulo, SP, Brazil.
Maria José Tavares
MJ
Ranzani-Paiva
D000818:Animals; D017756:Aquaculture; D001549:Benzamides / Q000494:pharmacology / Q000627:therapeutic use* / Q000633:toxicity; D060125:Characiformes / Q000469:parasitology*; D023681:Cichlids / Q000469:parasitology*; D016770:Ciliophora Infections / Q000517:prevention & control / Q000662:veterinary*; D005393:Fish Diseases / Q000469:parasitology / Q000517:prevention & control*; D016802:Oligohymenophorea / Q000187:drug effects*; D011897:Random Allocation
D001549:Benzamides; C052595:teflubenzuron
Drugs; Ecotoxicity; Fish disease; Treatment