Gold Nanocluster Embedded Albumin Nanoparticles for Two-Photon Imaging of Cancer Cells Accompanying Drug Delivery.
Gold nanoclusters in albumin nanoparticles (nanovehicles) are used for single-photon and two-photon imaging of cancer cells following the delivery of doxorubicin through the nanovehicle. NIR excitation and emission wavelengths in the biological window (650-900 nm) make the nanovehicle an ideal potential platform for imaging guided drug delivery.
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, 781039, India.
Rumi
R
Khandelia
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, 781039, India.
Satyapriya
S
Bhandari
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, 781039, India.
Uday Narayan
UN
Pan
Department of Biosciences and Bioengineering, Centre for Nanotechnology, Indian Institute of Technology Guwahati, Guwahati, 781039, India.
Siddhartha Sankar
SS
Ghosh
Department of Chemistry, Centre for Nanotechnology, Indian Institute of Technology Guwahati, Guwahati, 781039, India.
Arun
A
Chattopadhyay
D000418:Albumins / Q000008:administration & dosage / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000008:administration & dosage; D003952:Diagnostic Imaging / Q000379:methods; D004317:Doxorubicin / Q000008:administration & dosage*; D016503:Drug Delivery Systems / Q000379:methods; D006046:Gold / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D061848:Optical Imaging / Q000379:methods; D017785:Photons; D019265:Spectroscopy, Near-Infrared
D000418:Albumins; D000970:Antineoplastic Agents; D006046:Gold; D004317:Doxorubicin
albumin nanoparticles; cancer cells; drug delivery; gold nanoclusters; imaging; two-photon imaging