Accuracy of endoscopic ultrasonography for determination of tumor invasion depth in gastric cancer.
BACKGROUND
Gastric cancer (GC) is one the common lethal cancers in Iran. Detection of GC in the early stages would assesses to improve the survival of patients. In this study, we attempt to evaluate the accuracy of EUS in detection depth of invasion of GC among Iranian Patients.


METHODS
This study is a retrospective study of patients with pathologically confirmed GC. They underwent EUS before initiating the treatment. The accuracy of EUS and agreement between the two methods was evaluated by comparing pre treatment EUS finding with post operative histopathological results.


RESULTS
The overall accuracy of EUS for T and N staging was 67.9% and 75.47, respectively. Underestimation and overestimation was seen in 22 (14.2%) and 40 (25.6%) respectively. The EUS was more accurate in large tumors and the tumors located in the middle and lower parts of the stomach. The EUS was more sensitive in T3 staging. The values of weighted Kappa from the T and N staging were 0.53 and 0.66, respectively.


CONCLUSIONS
EUS is a useful modality for evaluating the depth of invasion of GC. The accuracy of EUS was higher if the tumor was located in the lower parts of the stomach and the size of the tumor was more than 3 cm. Therefore, judgments made upon other criteria evaluated in this study need to be reconsidered.
Hematology and Oncology Department, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran E-mail : sohrab_r@yahoo.com.
Seyed Mohsen
SM
Razavi
Mahmoud
M
Khodadost
Masoudreza
M
Sohrabi
Azam
A
Keshavarzi
Farhad
F
Zamani
Naser
N
Rakhshani
Mitra
M
Ameli
Reza
R
Sadeghi
Khadijeh
K
Hatami
Hossein
H
Ajdarkosh
Zeynab
Z
Golmahi
Mehdi
M
Ranjbaran
D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D019160:Endosonography / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*