Myopericytoma: A Series of 5 Cases Affecting the Nervous System.
BACKGROUND
Myopericytomas are benign vascular tumors composed of perivascular myoid cells that usually arise in superficial soft tissues of the extremities.


METHODS
We here report on 5 cases of myopericytoma, malignant myopericytoma, and glomangiopericytoma arising from subcutaneous, paraspinal, orbital, and sellar regions that secondarily involved the nervous system. Patients experienced orbital swelling, progressing neuropathic pain, dermatoma specific pain, and oculomotor paresis.


RESULTS
Mean age at diagnosis was 56.8 years (range, 38-74 years). After a mean follow-up of 38 months, no recurrence was detected. All tumors were unencapsulated but relatively well-circumscribed lesions, showing typical histologic and immunohistochemical features of soft-tissue myopericytoma, including one malignant case.


CONCLUSIONS
We conclude that myopericytoma may affect the nervous system and for prognostic and therapeutic reasons, needs to be differentiated from other vascular tumors.
Department of Neurosurgery, University Hospital Münster, Münster, Germany. Electronic address: hollingm@ukmuenster.de.
Markus
M
Holling
Department of Neurosurgery, Bergmannsheil Gelsenkirchen-Buer, Gelsenkirchen, Germany.
Uwe
U
Wildförster
Department of Neurosurgery, Bathildiskrankenhaus, Bad Pyrmont, Germany.
Raphaela
R
Verheggen
Institute of Neurology (Edinger Institute), Johann Wolfgang Goethe-University, Frankfurt/Main, Germany.
Klaus
K
Müller
Department of Neurosurgery, University Hospital Münster, Münster, Germany.
Walter
W
Stummer
Institute of Neuropathology, University Hospital Münster, Münster, Germany.
Astrid
A
Jeibmann
D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000601:surgery; D004172:Diplopia / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006393:Hemangiopericytoma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology; D009437:Neuralgia / Q000209:etiology; D009886:Ophthalmoplegia; D011379:Prognosis; D013120:Spinal Cord Neoplasms / Q000601:surgery; D019043:Vascular Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*
Glomangiopericytoma; Myopericytoma; Vascular tumors