Two-Stage Revision Protocol in Multidrug Resistant Periprosthetic Infection Following Total Hip Arthroplasty Using a Long Interval Between Stages.
We retrospectively reviewed the medical records of 31 patients with periprosthetic hip infections attempting to evaluate the outcome of a two-stage revision protocol characterized by prolonged interim period (mean=9.2 months, range 8-12 months) prior to the final re-implantation. In 3 cases (9.6%) the 1st stage was repeated after a mean period of 12.3 weeks due to relapse of infection. Five spacer dislocations occurred, not affecting the final clinical outcome after reimplantation, as evaluated by the Harris Hip Score. No protrusions or additional acetabular bone loss was noticed. Our proposed protocol is a simple, safe, efficient and reproducible treatment approach that may be successfully utilized predominantly when dealing with multidrug resistant pathogens.
2nd Orthopaedic Department, University of Athens Medical School, Konstantopouleio General Hospital Nea Ionia, Athens, Greece.
George C
GC
Babis
1st Department of Orthopaedics, Athens University Medical School, General University Hospital 'Attikon', Haidari, Greece.
Vasileios I
VI
Sakellariou
Orthopaedic Department, Asklepios Klinik Seligenstadt, Seligenstadt, Germany.
Panayiotis G
PG
Pantos
2nd Orthopaedic Department, University of Athens Medical School, Konstantopouleio General Hospital Nea Ionia, Athens, Greece.
Gregory G
GG
Sasalos
2nd Orthopaedic Department, University of Athens Medical School, Konstantopouleio General Hospital Nea Ionia, Athens, Greece.
Nikolaos A
NA
Stavropoulos
D000077:Acetabulum / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects* / Q000379:methods; D002908:Chronic Disease; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D016459:Prosthesis-Related Infections / Q000601:surgery*; D012008:Recurrence; D012086:Reoperation / Q000379:methods*; D012189:Retrospective Studies; D017334:Teicoplanin / Q000627:therapeutic use; D013997:Time Factors
D000900:Anti-Bacterial Agents; D017334:Teicoplanin
cement; complications; hip; infection; long interval; periprosthetic