Open-Loop Neurofeedback Audiovisual Stimulation: A Pilot Study of Its Potential for Sleep Induction in Older Adults.
This pilot study tested the efficacy of a 30-min audio-visual stimulation (AVS) program for the treatment of chronic insomnia in older adults. Chronic insomnia has been conceptualized as entailing increased cortical high frequency EEG activity at sleep onset and during NREM sleep. We hypothesized that an AVS program gradually descending from 8 to 1 Hz would potentially reduce the excessive cortical activation that is thought to contribute to difficulties with initiating and maintaining sleep. Accordingly, we conducted an intervention study of AVS using a pre-post design. Eight older adults (88 ± 8.7 years) complaining of chronic insomnia self-administered a 30-min AVS program nightly at bedtime for one month. Sleep was assessed at baseline and throughout the 4-week intervention. After using AVS for 4 weeks, significant improvement was reported in insomnia symptoms (ISI, p = 0.002) and sleep quality (PSQI, p = 0.004); with moderate to large effect sizes (Partial Eta2: 0.20-0.55)(Cohen's d: 0.7-2.3). The training effect (self-reported sleep improvement) was observed at the end of week one and persisted through the 1-month intervention. The results from this pilot study suggest that further exploration of AVS as a treatment for insomnia is warranted.
Health Science Center, School of Nursing, University of Washington, 1959 NE Pacific St., Box 357263, Seattle, WA, 98195-7263, USA, jeantang@u.washington.edu.
Hsin-Yi Jean
HY
Tang
Michael V
MV
Vitiello
Michael
M
Perlis
Barbara
B
Riegel
D000161:Acoustic Stimulation / Q000379:methods*; D000368:Aged; D000369:Aged, 80 and over; D058256:Brain Waves / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D058765:Neurofeedback / Q000379:methods*; D010775:Photic Stimulation / Q000379:methods*; D010865:Pilot Projects; D007319:Sleep Initiation and Maintenance Disorders / Q000628:therapy*; D016896:Treatment Outcome