Hepatocellular carcinoma in children.
Liver tumors are relatively rare in childhood, but may be associated with a range of diagnostic, genetic, therapeutic, and surgical challenges sufficient to tax even the most experienced clinician. This article outlines the epidemiology, etiology, pathologic condition, initial workup, and management of hepatocellular carcinoma in children and adolescents.
The Liver Unit, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK. Electronic address: deirdre.kelly@bch.nhs.uk.
Deirdre
D
Kelly
The Liver Unit, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK.
Khalid
K
Sharif
Department of Cellular Pathology, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Edgbaston, Birmingham B15 2WB, UK.
Rachel M
RM
Brown
Oncology Department, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK.
Bruce
B
Morland
D000293:Adolescent; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D002648:Child; D003937:Diagnosis, Differential; D006498:Hepatectomy; D018197:Hepatoblastoma / Q000175:diagnosis*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D016031:Liver Transplantation; D009367:Neoplasm Staging; D016896:Treatment Outcome
D000970:Antineoplastic Agents
Carcinoma; Epidemiology; Hepatocellular; Histopathology; Outcome; Pediatrics; Transplant