Selective disappearance of medial back muscles in a case of myotonic dystrophy type 1.
Here, we report a unique case of late-onset myotonic dystrophy type 1 in a 64-year-old woman, with selective disappearance of the medial lower back muscles. We compared the clinical features of this patient with those of a cohort of 29 patients with myotonic dystrophy type 1 to clarify the correlation between clinical features and lower back muscle atrophy. After classification into three subgroups according to muscle atrophy pattern, medial muscle atrophy was present in 17.2% of the patients. Affected patients were older at onset than non-affected patients, and limb muscle power and respiratory function decreased with atrophy progression.
Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.
Ryuta
R
Morihara
Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.
Nozomi
N
Hishikawa
Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.
Toru
T
Yamashita
Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.
Kentaro
K
Deguchi
Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, 2-5-1 Shikata-cho, Okayama 700-8558, Japan.
Tomoko
T
Kurata
Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, 2-5-1 Shikata-cho, Okayama 700-8558, Japan. Electronic address: p2k07ll9@cc.okayama-u.ac.jp.
Koji
K
Abe
D064131:Back Muscles / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009133:Muscular Atrophy / Q000209:etiology*; D009223:Myotonic Dystrophy / Q000150:complications* / Q000473:pathology*
Late onset; Myotonic dystrophy type 1; Paraspinal muscles