Physicochemical properties and release characteristics of starches from seeds of Indian Shahi Litchi.
Many conventional sources of starches are from staple foods. Non-conventional and cheap sources of starch are being explored. Starch was isolated from Shahi Litchi seeds using two extraction media; acidic (citric acid 0.3%, w/w; LC) and alkaline (NaOH 0.5%, w/w; LN). Each starch was investigated for various properties such as structural, morphological and functional. The percentage yield of LN and LC was 11% and 12.6%, respectively. Morphological properties of both starches show same structural makeup, but compound granules were in LN starch. Moisture content, amylose content was found to be higher LC starch than in LN starch, which indicates that extraction media affects the properties of starch. FTIR confirmed the carbohydrate nature of the both isolated starches. TGA data of both starches reveal slight difference in stability with temperature. In vitro release of both starches shows the release up to 58.95±0.04% and 67.184±0.07% in 5h for LN and LC, respectively, that indicates that these starches can be used in delayed drug delivery and targeting drugs to the colon.
Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi 835215, Jharkhand, India.
P
P
Jaiswal
Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology, Mesra, Ranchi 835215, Jharkhand, India. Electronic address: jayarampharm@gmail.com.
K Jayaram
KJ
Kumar
D000082:Acetaminophen / Q000737:chemistry*; D000688:Amylose / Q000032:analysis; D019343:Citric Acid / Q000737:chemistry; D004339:Drug Compounding; D065546:Drug Liberation; D007700:Kinetics; D059625:Liquid-Liquid Extraction / Q000379:methods; D032125:Litchi / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry*; D012972:Sodium Hydroxide / Q000737:chemistry; D013213:Starch / Q000737:chemistry* / Q000302:isolation & purification; D013607:Tablets / Q000032:analysis
D013607:Tablets; D019343:Citric Acid; D000082:Acetaminophen; D012972:Sodium Hydroxide; D013213:Starch; D000688:Amylose
Acidic extraction; Alkaline extraction; Delayed release; Shahi Litchi seed; Starch