Prolonged adrenal insufficiency after unilateral adrenalectomy for Cushing's Syndrome.
The contralateral healthy adrenal in patients undergoing unilateral adrenalectomy for Cushing's is known to be suppressed temporarily and forms the basis of peri and postoperative steroids. We present four cases of Cushing's who had prolonged adrenal insufficiency with continued requirement for steroids for periods ranging 1-4 years after unilateral adrenalectomy for Cushing's. We further review literature regarding the recovery of the hypothalamo pituitary adrenal axis postsurgery in patients with Cushing's syndrome.
Department of Endocrinology, PGIMER, Dr. RML Hospital, New Delhi, India.
Bindu
B
Kulshreshtha
Department of Endocrinology, PGIMER, Dr. RML Hospital, New Delhi, India.
Arpita
A
Arora
Department of Endocrinology, PGIMER, Dr. RML Hospital, New Delhi, India.
Anshita
A
Aggarwal
Department of Pathology, PGIMER, Dr. RML Hospital, New Delhi, India.
Minakshi
M
Bhardwaj
Adrenal insufficiency; Cushing's syndrome; unilateral adrenalectomy