Synthesis, reactivity, and biological activity of 5-aminouracil and its derivatives.
The synthesis and reactions of 5-aminouracil and its derivatives are comprehensively reviewed. A brief survey of biological activities, especially chemotherapeutic and pharmacological properties, is also reported.
Chemistry Department, Faculty of science, Minia University, El-Minia, 61519, Egypt. rmshaker@yahoo.com.
Raafat Mohamed
RM
Shaker
Chemistry Department, Faculty of science, Minia University, El-Minia, 61519, Egypt.
Mohamed
M
Abd Elrady
Chemistry Department, Faculty of science, Minia University, El-Minia, 61519, Egypt. kusadek@yahoo.com.
Kamal Usef
http://orcid.org/0000-0003-4342-5394
KU
Sadek
D003500:Cyclization; D006801:Humans; D008958:Models, Molecular; D015394:Molecular Structure; D014498:Uracil / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D014498:Uracil; C011166:5-aminouracil
5-Aminouracil; Chemotherapeutic interest; Pharmacological interest; Reactivity; Synthesis