A sensitive colorimetric strategy for monitoring cerebral β-amyloid peptides in AD based on dual-functionalized gold nanoplasmonic particles.
A sensitive and selective strategy for the colorimetric visualization of the total monomeric Aβ down to 40 pg mL(-1) based on dual-functionalized gold nanoplasmonic particles (GNPs) is developed and applied to evaluate Aβ levels in the AD cerebral system.
Department of Pharmaceutical Analysis, Xuzhou Medical College, 209 Tongshan Road, Xuzhou 221004, P. R. China.
Yan-yan
YY
Yu
Lin
L
Zhang
Xiao-yu
XY
Sun
Cheng-lin
CL
Li
Yu
Y
Qiu
Hao-peng
HP
Sun
Dao-quan
DQ
Tang
Yao-wu
YW
Liu
Xiao-xing
XX
Yin
D000544:Alzheimer Disease / Q000175:diagnosis* / Q000378:metabolism*; D016229:Amyloid beta-Peptides / Q000032:analysis* / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism*; D003124:Colorimetry; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000032:analysis / Q000737:chemistry*; D015394:Molecular Structure; D010316:Particle Size; D051381:Rats; D013499:Surface Properties
D016229:Amyloid beta-Peptides; D006046:Gold