Efficacy of indacaterol as a single therapy versus salmeterol/fluticasone therapy in patients with milder chronic obstructive pulmonary disease.
BACKGROUND
In non-exacerbation chronic obstructive pulmonary disease (COPD) with mild lung function impairment, single bronchodilator therapy might be as effective as combined inhaled corticosteroid/bronchodilator therapy, whereas the risk of pneumonia associated with the latter would be practically absent.


METHODS
We performed an analysis of a recent study evaluating the efficacy and safety of inhaled indacaterol versus inhaled salmeterol/fluticasone in COPD patients.


CONCLUSIONS
Both therapies were found to exert comparable effects on lung function, symptom severity and health status.
University of Oradea , Oradea , Romania.
Ulmeanu
U
Ruxandra
Sabina Antonela
SA
Antoniu
Florin
F
Mihaltan
Daniela
D
Boisteanu
D000420:Albuterol / Q000031:analogs & derivatives*; D000730:Androstadienes / Q000627:therapeutic use*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007189:Indans / Q000627:therapeutic use*; D008297:Male; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy*; D015363:Quinolones / Q000627:therapeutic use*
D000730:Androstadienes; D001993:Bronchodilator Agents; D005938:Glucocorticoids; D007189:Indans; D015363:Quinolones; D000420:Albuterol
chronic obstructive pulmonary disease; indacaterol; phenotype; salmeterol/fluticasone