Domain repeats related to innate immunity in the South African abalone, Haliotis midae.
Molluscs predominately use the cellular defence system as the primary mechanism of defence against pathogenic infection, in which haemocytes play a pivotal role. Haliotis midae is a commercially important South African species that it is susceptible to bacterial pathogens, fungal and yeast infections in the farming environment. The current study aims to enrich the current knowledge regarding H. midae innate immunity by investigating the presence and evolution of domain repeats. The bioinformatics approach used in this study, detected five repeat families in the H. midae transcriptome. These repeats families include mixed alpha and beta (leucine-rich and ankyrin), spectrin repeats, beta-propellers (WD40) and alfa-structure repeat (TPR-like). The expansion of key gene families related to host defence may be important to abalone adaptation to life in a pathogen-rich environment.
Department of Genetics, Stellenbosch University, van der Bijl Street, JC Smuts Building, Private Bag X1, Matieland 7602, South Africa. Electronic address: barbara.picone@gmail.com.
Barbara
B
Picone
Department of Genetics, Stellenbosch University, van der Bijl Street, JC Smuts Building, Private Bag X1, Matieland 7602, South Africa.
Clint
C
Rhode
Department of Genetics, Stellenbosch University, van der Bijl Street, JC Smuts Building, Private Bag X1, Matieland 7602, South Africa.
Rouvay
R
Roodt-Wilding
D000818:Animals; D007113:Immunity, Innate / Q000235:genetics*; D008974:Mollusca / Q000235:genetics* / Q000276:immunology / Q000382:microbiology; D010802:Phylogeny; D011506:Proteins / Q000235:genetics / Q000378:metabolism; D013019:South Africa
D011506:Proteins
Expansion; Gastropods; Haliotidae; Immunity; Repeat domains