Primary CNS T-cell lymphoma of the spinal cord: case report and literature review.
Primary central nervous system lymphoma (PCNSL) accounts for 1% of all lymphoma diagnoses and as many as 6% of all central nervous system (CNS) tumors. Most cases of PCNSL are of B-cell type; few are of T-cell lineage. PCNSL mainly occurs intracranially; primary spinal-cord lymphoma only occurs rarely. Moreover, intramedullary presentation without intracranial lesions is virtually unknown. Herein, we present a case of primary T-cell CNS lymphoma limited to the intramedullary spinal cord in an 82-year-old white man, along with a review of the literature on this condition and similar conditions.
Department of Pathology, Hoftstra North Shore-LIJ Health System, Hempstead, NY.
Melissa
M
Guzzetta
Department of Pathology, Winthrop-University Hospital, Mineola, NY sdrexler@winthrop.org.
Steven
S
Drexler
Department of Radiology, Winthrop-University Hospital, Mineola, NY.
Brian
B
Buonocore
Department of Pathology, Winthrop-University Hospital, Mineola, NY.
Virginia
V
Donovan
D000369:Aged, 80 and over; D015703:Antigens, CD / Q000378:metabolism; D006801:Humans; D016399:Lymphoma, T-Cell / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D013120:Spinal Cord Neoplasms / Q000473:pathology*
D015703:Antigens, CD
CNS T-cell lymphoma; Primary CNS lymphoma; primary intramedullary spinal cord lymphoma