The comparison of the influence between two different bowel preparation methods on sepsis after prostate biopsies.
BACKGROUND
Transrectal ultrasonography (TRUS) guided prostate needle biopsy has been performed to diagnose and stage prostate cancer for many years. There are many different bowel preparation protocols to diminish the infectious complications, but there is no standardized consensus among urologists. Therefore, we aimed to assess two different bowel preparation methods on the rate of infectious complications in patients who underwent TRUS-guided prostate biopsy.


METHODS
A total of 387 cases of TRUS-guided prostate biopsy were included in this retrospective study. All patients received antibiotic prophylaxis with ciprofloxacin (500 mg) twice a day orally for 7 days starting on the day before the biopsy. The patients were divided into two groups according to the bowel preparation method used. Patients (Group 1, n = 164) only received self-administrated phosphate enema) on the morning of the prostate biopsy. Other patients (Group 2, n = 223) received sennasoid a-b laxatives the night before the prostate biopsy. Infectious complications were classified as sepsis, fever (greater than 38°C) without sepsis, and other clinical infections.


RESULTS
Major complications developed in 14 cases (3.8%), including 3 cases (0.8%) of urinary retention, and 11 (3%) infectious complications, all of which were sepsis. There were 3 and 8 cases of urosepsis in Group 1 and Group 2, respectively. There were no statistically significant differences between both Groups regarding to the rates of urosepsis (p = 0.358).


CONCLUSIONS
Despite both methods of bowel preparation, sodium phosphate enema or sennasoid a-b calcium laxatives, before TRUS-guided prostate biopsy have similar effect on the rate of urosepsis, so both methods of bowel preparation can be safely used.
Turgut Ozal University School of Medicine Department of Urology, Ankara, Turkey.
Mehmet Erol
ME
Yildirim
Yüksek İhtisas Training and Research Hospital Department of Urology, Ankara, Turkey.
Huseyin
H
Badem
Turgut Ozal University School of Medicine Department of Urology, Ankara, Turkey.
Mucahit
M
Cavis
Turgut Ozal University School of Medicine Department of Urology, Ankara, Turkey.
Omer Faruk
OF
Karatas
Turgut Ozal University School of Medicine Department of Urology, Ankara, Turkey.
Ersin
E
Cimentepe
Hacettepe University School of Medicine Department of Urology, Ankara, Turkey.
Dogan
D
Unal
Turgut Ozal University School of Medicine Department of Urology, Ankara, Turkey.
Ilkay Bekir
IB
Incebay
bowel preparation; prostate biopsy; prostate cancer