Coronary periarteritis in a patient with multi-organ IgG4-related disease.
Immunoglobulin G4-related disease is a recently described systemic clinicopathological entity characterized by immunoglobulin G4-producing plasmacytic infiltration of tissue and frequently by elevated serum immunoglobulin G4 concentration. Manifestations of this disease have been documented in nearly all organs and locations, but coronary artery involvement is not widely recognized. We report the coronary findings of a patient with multi-organ immunoglobulin G4-related disease. Non-electrocardiogram-gated computed tomography of the chest demonstrated nodular and rind-like periarterial soft tissue thickening along the proximal coronary artery segments with improvement following steroid therapy.
School of Medicine, UC San Diego, San Diego, CA, USA.
Yueyang
Y
Guo
Department of Radiology, UC San Diego Health System, San Diego, CA, USA.
David
D
Ansdell
Department of Radiology, UC San Diego Health System, San Diego, CA, USA.
Sharon
S
Brouha
Department of Radiology, UC San Diego Health System, San Diego, CA, USA.
Andrew
A
Yen
D000369:Aged, 80 and over; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000627:therapeutic use; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D006942:Hypergammaglobulinemia / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000276:immunology*; D007074:Immunoglobulin G / Q000276:immunology*; D008297:Male; D010493:Pericarditis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000276:immunology*; D011241:Prednisone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D007074:Immunoglobulin G; D011241:Prednisone
PET; cardiac; computed tomography; coronary periarteritis; immunoglobulin G4-related disease