Peptides at the blood brain barrier: Knowing me knowing you.
When the Davis Lab was first asked to contribute to this special edition of Peptides to celebrate the career and influence of Abba Kastin on peptide research, it felt like a daunting task. It is difficult to really understand and appreciate the influence that Abba has had, not only on a generation of peptide researchers, but also on the field of blood brain barrier (BBB) research, unless you lived it as we did. When we look back at our careers and those of our former students, one can truly see that several of Abba's papers played an influential role in the development of our personal research programs.
The Davis Lab, Department of Medical Pharmacology, University of Arizona, Tucson, AZ 85724-5050. Electronic address: davistp@email.arizona.edu.
Thomas P
TP
Davis
Texas Tech University Health Sciences Center, School of Pharmacy, Amarillo, TX 79106.
Thomas J
TJ
Abbruscato
Joan C. Edwards School of Medicine at Marshall University, Huntington, WV 25755.
Richard D
RD
Egleton
D000818:Animals; D035843:Biomedical Research / Q000266:history; D001812:Blood-Brain Barrier / Q000378:metabolism*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D010455:Peptides / Q000266:history / Q000378:metabolism*; D021381:Protein Transport / Q000502:physiology
D010455:Peptides
Blood brain barrier; Drug delivery; Neuropeptides; P-glycoprotein; Tight junction proteins; Transporter proteins