In vitro functional properties of crude extracts and isolated compounds from banana pseudostem and rhizome.
BACKGROUND
Pseudostem and rhizome are the significant bio-waste generated (43.48%) from the banana plant post fruit harvest, which are usually left in the plantation or incinerated and wasted. Amounts used in production for consumption are negligible. However, the material has an important part to play in indigenous systems of medicine. Based on the huge volume of bio-waste generated and its traditional medicinal use, it is worth exploiting it as a source of natural bioactive compounds. In the current study, sequential extracts from banana pseudostem (BPS) and rhizome (BR), and isolated compounds including chlorogenic acid, 4-epicyclomusalenone and cycloeucalenol acetate, were tested for their antimicrobial activity, antiplatelet aggregation and cytotoxicity.


RESULTS
Isolated compounds and crude extracts exhibited strong antimicrobial activity against a wide range of bacterial and fungal strains, platelet aggregation induced by collagen and cytotoxicity towards human liver cancer (HepG2) cells.


CONCLUSIONS
Banana plant bio-waste, pseudostem and rhizome may serve as a potential source of multifunctional bioactive compounds and functional ingredient in food and other allied industries.
Amity International Centre for Post Harvest Technology and Cold Chain Management, Amity University, Noida 201303, Uttar Pradesh, India.
Saravanan
S
Kandasamy
Department of Biotechnology, School of Bioengineering, SRM University, Kattankulathur, Chennai -603203, Tamilnadu, India.
Sasikala
S
Ramu
Department of Fruit and Vegetable Technology, CSIR - Central Food Technological Research Institute, Mysore 570020, Karnataka, India.
Somaradhya Mallikarjuna
SM
Aradhya
D000383:Agriculture / Q000379:methods; D000890:Anti-Infective Agents; D000972:Antineoplastic Agents, Phytogenic; D002726:Chlorogenic Acid / Q000302:isolation & purification / Q000494:pharmacology; D056945:Hep G2 Cells; D006801:Humans; D007220:Industrial Waste; D008113:Liver Neoplasms / Q000188:drug therapy; D028521:Musa / Q000737:chemistry*; D010840:Phytosterols / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology; D018547:Plant Stems / Q000737:chemistry*; D010975:Platelet Aggregation Inhibitors; D027343:Rhizome / Q000737:chemistry*
D000890:Anti-Infective Agents; D000972:Antineoplastic Agents, Phytogenic; D007220:Industrial Waste; D010840:Phytosterols; D010936:Plant Extracts; D010975:Platelet Aggregation Inhibitors; D002726:Chlorogenic Acid; C007198:cycloleucalenol
4-epicyclomusalenone; antimicrobial activity; banana pseudostem and banana rhizome; chlorogenic acid; cycloeucalenol acetate; cytotoxicity; platelet aggregation inhibitory activity