Secondary metabolites for antiulcer activity.
Peptic ulcers are open sores or erosions in the lining of either the duodenum (duodenal ulcers) or the stomach (gastric ulcers). Peptic ulcer, which is mainly caused by bacterial attack or excess of acid secretion, can be cured effectively by these isolated plant compounds. In this present scenario, demand for herbal medicines are increasing due to easy availability in surrounding place at low cost. This review article is all about such isolated plant compounds such as alkaloids, flavonoids and terpenoids. Various plants have been used as folk medicine by the people of rural area, which shows significant effect against peptic ulcer. Further study should be conducted upon these herbal plants because there is possibility for minimising the adverse effect caused by the present antiulcer drugs.
a Department of Pharmacology, Institute of Pharmaceutical Sciences , Guru Ghasidas Vishwavidyalaya , Koni, Bilaspur , Chhattisgarh 495009 , India.
Parag
P
Jain
D000470:Alkaloids / Q000302:isolation & purification / Q000494:pharmacology; D000897:Anti-Ulcer Agents / Q000302:isolation & purification* / Q000494:pharmacology; D004381:Duodenal Ulcer / Q000188:drug therapy; D004386:Duodenum / Q000187:drug effects; D005419:Flavonoids / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D008519:Medicine, Traditional; D015394:Molecular Structure; D010437:Peptic Ulcer / Q000188:drug therapy*; D028321:Plant Preparations / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D064210:Secondary Metabolism; D013276:Stomach Ulcer / Q000188:drug therapy; D013729:Terpenes / Q000302:isolation & purification / Q000494:pharmacology
D000470:Alkaloids; D000897:Anti-Ulcer Agents; D005419:Flavonoids; D028321:Plant Preparations; D013729:Terpenes
alkaloids; flavonoids; peptic ulcer; secondary metabolites; terpenoids