Isolated diastolic hypertension associated risk factors among Chinese in Anhui Province, China.
OBJECTIVE
To explore potential risk factors of isolated diastolic hypertension (IDH) among young and middle-aged Chinese.


METHODS
A community-based cross-sectional study was conducted among 338 subjects, aged 25 years and above, using random sampling technique. There were 68 cases of IDH, 46 cases of isolated systolic hypertension (ISH), 89 cases of systolic and diastolic hypertension (SDH), and 135 of subjects with normal blood pressure. Cases and controls were matched on sex by frequency matching. Demographic characteristics, blood pressure and other relevant information were collected.


RESULTS
Compared with controls, patients with IDH and ISH had significant higher level of triglyceride, high density lipoprotein, blood glucose and body mass index (BMI) (p < 0.05); while patients with SDH had significantly higher level of total cholesterol, triglyceride, glucose and BMI (p < 0.05). Linear mixed effects model showed that drinking tea, family history of hypertension (FHH), higher blood glucose, triglyceride and low density lipoprotein were related with elevated diastolic blood pressure (DBP) (p < 0.01); HFH, blood glucose, creatinine and BMI have positive effect on systolic blood pressure (SBP) (p < 0.05).


CONCLUSIONS
Drinking tea, FHH, high levels of triglyceride, high density lipoprotein, blood glucose and BMI are associated with IDH among young and middle-aged Chinese.
School of Public Health, Wannan Medical College, Wuhu 241002, China. wangyanchun2006@163.com.|The Department of Pathology, School of Medicine, The Fourth Affiliated Hospital, Zhejiang University, Yiwu 322000, China. wangyanchun2006@163.com.
Yanchun
Y
Wang
School of Public Health, Wannan Medical College, Wuhu 241002, China. xfj_8@live.com.
Fengjun
F
Xing
School of Public Health, Wannan Medical College, Wuhu 241002, China. 18575582924@163.com.
Rongjuan
R
Liu
School of Public Health, Wannan Medical College, Wuhu 241002, China. 18255310119@wnmc.edu.
Li
L
Liu
School of Public Health, Wannan Medical College, Wuhu 241002, China. kutuomonk@foxmail.com.
Yu
Y
Zhu
School of Public Health, Wannan Medical College, Wuhu 241002, China. wyf@wnmc.edu.cn.
Yufeng
Y
Wen
School of Food Science, Guangdong Pharmaceutical University, Zhongshan 528458, China. wsun3@tulane.edu.|School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA. wsun3@tulane.edu.
Wenjie
W
Sun
School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA. zsong1@tulane.edu.
Ziwei
Z
Song
D000328:Adult; D044466:Asian People; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D002784:Cholesterol / Q000097:blood; D003430:Cross-Sectional Studies; D003971:Diastole; D004326:Drinking; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000453:epidemiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013662:Tea; D014280:Triglycerides / Q000097:blood
D001786:Blood Glucose; D013662:Tea; D014280:Triglycerides; D002784:Cholesterol