Essential oil composition and antimicrobial activity of Vismia macrophylla leaves and fruits collected in Táchira-Venezuela.
Hydrodistillation of Vismia macrophylla Kunth (Hypericaceae) leaves (L) and fruits (F) yielded 1.3%, v/w, and 5.6%, v/w, of essential oil, respectively. GC and GC-MS analyses showed the presence of twenty-four (96.4%, L) and thirty-one (96.6%, F) components, respectively. Major compounds identified in the leaf oil were γ-bisabolene (44.4%) and β-bisabolol (14.9%), while those in the fruit oil were germacrene-D (12.1%), 6-cadinene (10.7%) and γ-bisabolene (22.3 %). Oil obtained from the fruits of V. macrophylla showed antibacterial activity against Gram-positive (S. aureus ATCC 25923 and E. faecalis ATCC 29212) as well as Gram-negative bacteria (E. coli ATCC 25922), with MIC values ranging from 150 μL/mL to 740 μL/mL. Oil obtained from leaves were active only on the Gram-positive bacteria S. aureus (100 μL/mL) and E. faecalis (500 μL/mL), but also showed antiyeast activity against Candida albicans CDC-B385 and C. krusei ATCC 6258 (600 μL/mL, each).
Alexis
A
Buitrago
Janne
J
Rojas
Luis
L
Rojas
Judith
J
Velasco
Antonio
A
Morales
Yonel
Y
Peñaloza
Clara
C
Díaz
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D028084:Clusiaceae / Q000737:chemistry*; D005638:Fruit / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology*; D014687:Venezuela
D000900:Anti-Bacterial Agents; D009822:Oils, Volatile; D010938:Plant Oils