Spread of extended-spectrum beta-lactamase-producing Escherichia coli from a swine farm to the receiving river.
The dissemination of drug-resistant bacteria into different environments has posed a grave threat to public health, but data on the spread of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (E. coli) from animal farms to the receiving river are limited. Here, 57 ESBL-producing E. coli isolated from a pig farm and the receiving river were analyzed in terms of drug resistance, ESBL genes, and enterobacterial repetitive intergenic consensus (ERIC). The results showed that ESBL-producing E. coli from swine feces and downstream water of the pig farm outfall overlapped substantially in drug resistance and ESBL genes. Additionally, six ESBL-producing E. coli from the downstream water exhibited 100 % genetic similarity with strains from the swine feces. In conclusion, effluents of animal farms are a likely contributor to the presence of ESBL-producing E. coli in aquatic environments.
College of Basic Medicine, Taishan Medical University, Taian, 271000, China.
Song
S
Li
Wengang
W
Song
Yufa
Y
Zhou
Yujing
Y
Tang
Yanxia
Y
Gao
Zengmin
Z
Miao
D000383:Agriculture; D000818:Animals; D002681:China; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D029968:Escherichia coli Proteins / Q000096:biosynthesis / Q000235:genetics*; D005243:Feces / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D010802:Phylogeny; D045483:Rivers / Q000382:microbiology*; D013552:Swine; D014871:Water Microbiology; D018440:beta-Lactam Resistance / Q000235:genetics; D001618:beta-Lactamases / Q000096:biosynthesis / Q000235:genetics*
D029968:Escherichia coli Proteins; D001618:beta-Lactamases