[Evaluating the effectiveness of dietary management of patients with varying degrees of obesity].
The purpose of the research is to study the efficiency of a low-calorie diet in treatment of patients with various degree of expressiveness of obesity. 605 patients (188 men and 417 women) with a body mass index > 25 kg/m2 at age 18-79 years have been examined. All patients underwent a complex clinical and instrumental and laboratory examination on the "Nutritest IP-2" system, including studying of clinical status dynamics, anthopometrical indicators, composite structure of a body, parameters of a power exchange and the laboratory indicators characterizing a condition of lipid, carbohydrate and protein metabolism. It has been revealed that low-calorie diet in combination with traditional curative measures ("Nutrikor IP-2") in obese patients significantly improved clinical status, central hemodynamics (blood pressure and heart rate), anthropometric parameters and body composition, lipid profile and parameters of metabolic status. In particular, systolic arterial pressure decreased authentically by 18- 19% (p < 0.00I), diastolic arterial pressure--was reliable for 16-17% (p < 0.001), heart rate authentically decreased by 7-12% (p < 0.001). Concentration of blood glucose authentically decreased at patients with obesity of I and II degrees--by 6% (p < 0.01), at patients with obesity of the III degrees--for 8% (p < 0.001). The reduction of fatty body weight in patients without obesity was 2.3%, in patients with I degree of obesity--3.1% (p < 0.001), in patients with II degree of obesity--3.4% (p < 0.001), and in patients with III degree of obesity--4% (p < 0.001). It has been shown that the effectiveness of therapeutic interventions reduced according to the severity of obesity, that requires changes in the approach to the treatment of these patients, the search for new methods of drug and dietary management of this pathology.
A R
AR
Bogdanov
S A
SA
Derbeneva
A V
AV
Pogozheva
T V
TV
Sentsova
D000293:Adolescent; D000328:Adult; D000368:Aged; D000886:Anthropometry; D001794:Blood Pressure / Q000502:physiology; D031204:Caloric Restriction / Q000379:methods*; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004041:Dietary Fats / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D005260:Female; D038321:Glycemic Index; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000150:complications / Q000178:diet therapy* / Q000503:physiopathology; D012720:Severity of Illness Index; D055815:Young Adult
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins