Outbreak of NDM-1-producing Klebsiella pneumoniae causing neonatal infection in a teaching hospital in mainland China.
The emergence and spread of bacteria carrying the bla(NDM-1) gene has become a worldwide concern. Here, we report eight cases of Klebsiella pneumoniae with bla(NDM-1) in the neonatal ward of a teaching hospital in mainland China. Multilocus sequence typing showed that seven isolates were clonally related and confirmed them as sequence type 17 (ST17). One isolate belonged to ST433. These findings suggest continuous spread of bla(NDM-1) in mainland China and emphasize the need for intensive surveillance and precautions.
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
XiaoYu
X
Zhang
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
XianPing
X
Li
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China wangmin0000@aliyun.com.
Min
M
Wang
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
HeJia
H
Yue
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
PengLing
P
Li
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
YaPing
Y
Liu
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
Wei
W
Cao
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
DongMei
D
Yao
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
Li
L
Liu
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
XiaoLan
X
Zhou
Clinical Laboratory Department, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
Rong
R
Zheng
Department of Pediatrics, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People's Republic of China.
Tao
T
Bo
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002681:China; D004269:DNA, Bacterial / Q000235:genetics; D004760:Enterocolitis / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007710:Klebsiella Infections / Q000188:drug therapy / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000235:genetics*; D008297:Male; D018805:Sepsis / Q000382:microbiology; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1