Spontaneous coronary artery dissection associated with fibromuscular dysplasia.
This case presentation concerns a woman known to have fibromuscular dysplasia (FMD) who presented with an acute coronary syndrome (ACS). The coronary angiogram was considered to be normal. However, as spontaneous coronary artery dissection (SCAD) has a close association with FMD, subsequent meticulous review of the angiogram revealed a dissection within the circumflex coronary artery. SCAD causes 10% of ACS seen in women under 55 years of age. Both FMD and SCAD are underdiagnosed and SCAD may be overlooked or misdiagnosed on coronary angiography. The recommended management of SCAD differs from that of the usual presentations of ACS. For this reason, one should be alert to the possibility of SCAD when confronted by ACS in a younger woman, especially when she is known to have FMD.
Milpark Hospital, Johannesburg, South Africa. ajd@hot.co.za.
Anthony J
AJ
Dalby
Sunninghill Hospital, Johannesburg.
Lewis J
LJ
Levien
D000208:Acute Disease; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D017023:Coronary Angiography; D003330:Coronary Vessel Anomalies / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D018572:Disease-Free Survival; D015914:Estrogen Replacement Therapy; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D014652:Vascular Diseases / Q000150:complications / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy; D028761:Withholding Treatment
D000319:Adrenergic beta-Antagonists; D010975:Platelet Aggregation Inhibitors