Regiospecific Benzoylation of Electron-Deficient N-Heterocycles with Methylbenzenes via a Minisci-Type Reaction.
A regioselective cross-dehydrogenative coupling between electron-deficient N-heterocycles (isoquinoline, quinolines, and quinoxalines) and methylbenzenes leading to regiospecific C-aroylation has been accomplished using AlCl3 as the catalyst in the presence of oxidant TBHP. This protocol is a practical alternative to the classical Minisci reaction.
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
Wajid
W
Ali
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
Ahalya
A
Behera
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
Srimanta
S
Guin
Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, India.
Bhisma K
BK
Patel