Comparison of Pathological Radicality between Open and Laparoscopic Pancreaticoduodenectomy in a Tertiary Centre.
Laparoscopic pancreaticoduodenectomy (LPD) remained a formidable challenge owing to retroperitoneal location, difficult dissection near great vessels and critical intracorporeal anastomoses. Recent reviews of literature have established the feasibility and comparable short term outcomes of laparoscopic pancreaticoduodenectomy (LPD) with that of open pancreaticoduodenectomy (OPD). This study was undertaken to compare the pathological radicality of LPD with OPD. A prospective database of all patients who underwent standard pancreaticoduodenectomy from Mar 2006 to Feb 2011 was taken up for this study. 45 patients who underwent LPD and 118 patients who underwent OPD for periampullary and pancreatic head malignancy were taken up for analysis. The study groups were comparable in terms of age of presentation, ASA grades, comorbidity, type of surgery and BMI. There was no statistically significant difference with regard to tumor size, lymph node yield, node positivity rates, R1 rates and margin lengths. The pathological radicality of laparoscopic pancreaticoduodenectomy is comparable with that of open approach when performed by experienced minimal-access surgeons. Standardized protocols for evaluation of the resection margins should be mandatory in studies reporting outcomes of pancreaticoduodectomy.
Gem Hospital and Research Centre, Minimal Access and HPB Surgery Coimbatore, Tamil Nadu, 641045 India.
Palanisamy
P
Senthilnathan
Gem Hospital and Research Centre, Minimal Access and HPB Surgery Coimbatore, Tamil Nadu, 641045 India.
Palanivelu
P
Chinnusamy
Gem Hospital and Research Centre, Minimal Access and HPB Surgery Coimbatore, Tamil Nadu, 641045 India.
Alwar
A
Ramanujam
Gem Hospital and Research Centre, Minimal Access and HPB Surgery Coimbatore, Tamil Nadu, 641045 India.
Srivatsan Gurumurthy
SG
Sivakumar
Gem Hospital and Research Centre, Minimal Access and HPB Surgery Coimbatore, Tamil Nadu, 641045 India.
Anand Vijai
AV
Natesan
Gem Hospital and Research Centre, Minimal Access and HPB Surgery Coimbatore, Tamil Nadu, 641045 India.
C
C
Chandramaliteeswaran
Gem Hospital and Research Centre, Minimal Access and HPB Surgery Coimbatore, Tamil Nadu, 641045 India.
Praveen Raj
PR
Palanivelu
Gem Hospital and Research Centre, Minimal Access and HPB Surgery Coimbatore, Tamil Nadu, 641045 India.
Parthasarathi
P
Ramakrishnan
Gem Hospital and Research Centre, Minimal Access and HPB Surgery Coimbatore, Tamil Nadu, 641045 India.
Rajapandian
R
Subbiah
Adenocarcinoma; Outcomes; Pancreatic neoplasia; Peri-ampullary tumours; Resection