Successful treatment of immediate allogeneic myeloablative hematopoietic stem cell transplantation from a HLA-mismatched sibling donor for active systemic epstein-barr virus-positive T-cell lymphoproliferative disease of childhood following primary acute epstein-barr virus infection.
A 22-year-old female was admitted for sustained high fever and diagnosed with systemic Epstein-Barr virus-positive T-cell lymphoproliferative disease. As her clinical course was so aggressive, she immediately underwent allogeneic myeloablative bone marrow transplantation from an HLA-mismatched sibling donor on hospital day 46. The patient has remained in complete remission for 3 years.
Department of Hematology, Asahikawa City Hospital Asahikawa, Japan.
Yasutaka
Y
Kakinoki
Department of Hematology, Hokkaido University Graduate School of Medicine Sapporo, Japan.
Satomi
S
Matsuoka
Department of Hematology, Asahikawa City Hospital Asahikawa, Japan.
Junichi
J
Hashiguchi
Department of Hematology, Asahikawa City Hospital Asahikawa, Japan.
Koji
K
Chiba
Department of Hematology, Asahikawa City Hospital Asahikawa, Japan.
Takayoshi
T
Miyake
EBV-positive T-cell LPD; HPS; HSCT; MAC