Tramadol in palliative care #290.
Tramadol has an important position as a Step II agent on the WHO pain ladder, where it is effective for a variety of syndromes in patients with mild to moderate pain intensity. Its recommended dosing adjustments, potential ceiling effect, cost, pertinent drug interactions, and risk for significant adverse drug reactions may limit its chronic use in patients with significant pain.
Jennifer
J
Pruskowski
Robert M
RM
Arnold
D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology; D004347:Drug Interactions; D006801:Humans; D010146:Pain / Q000188:drug therapy*; D010166:Palliative Care / Q000379:methods*; D014147:Tramadol / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology
D000701:Analgesics, Opioid; D014147:Tramadol