[HIV may be cured].
The symposium IAS Towards an HIV Cure was held in Melbourne, Australia, in July 2014. There are several challenges regarding an HIV cure, among these the reservoir of latently infected CD4+ T cells which are hidden from the immune system. A new promising approach towards an HIV cure is the "shock and kill" strategy. Here, the latently infected cells are shocked to express HIV on the surface, and afterwards the shocked cells can be eradicated by apoptosis or destruction by the immune system. In this paper the most important results from the symposium are presented.
Infektionsmedicinsk Afdeling Q, Aarhus Universitetshospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N. as.kjaer@outlook.com.
Anne Sofie Høgh Kølbæk
AS
Kjær
Helena Bleken
HB
Østergaard
D019380:Anti-HIV Agents / Q000627:therapeutic use*; D015496:CD4-Positive T-Lymphocytes / Q000187:drug effects / Q000821:virology; D003226:Congresses as Topic; D006678:HIV / Q000187:drug effects* / Q000276:immunology / Q000502:physiology; D015658:HIV Infections / Q000188:drug therapy* / Q000276:immunology; D056572:Histone Deacetylase Inhibitors / Q000627:therapeutic use*; D006801:Humans; D012955:Societies, Medical; D014775:Virus Activation / Q000187:drug effects; D017735:Virus Latency / Q000187:drug effects
D019380:Anti-HIV Agents; D056572:Histone Deacetylase Inhibitors