Endocytosis and its regulation in plants.
Endocytosis provides a major route of entry for membrane proteins, lipids, and extracellular molecules into the cell. Recent evidence indicates that multiple cellular processes require endocytosis, including nutrient uptake, signaling transduction, and plant-microbe interactions. Also, advanced microscopy, combined with biochemical and genetic approaches, has provided more insights into the molecular machinery and functions of endocytosis in plants. Here we review mechanisms of the clathrin-dependent and membrane microdomain-associated endocytic routes in plant cells. In addition, degradation of endocytosed proteins and endosomal sorting complex required for transport (ESCRT)-mediated vesicle formation at the endosome are discussed. Finally, we summarize the essential roles of various regulators during plant endocytosis.
College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, China; Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China.
Lusheng
L
Fan
College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, China.
Ruili
R
Li
College of Chemistry and Life Sciences, Zhejiang Normal University, Zhejiang 321004, China.
Jianwei
J
Pan
The Key Laboratory of Plant Cell Engineering and Germplasm Innovation, Ministry of Education, School of Life Sciences, Shandong University, Jinan 250100, China.
Zhaojun
Z
Ding
College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, China. Electronic address: Linjinxing@bjfu.edu.cn.
Jinxing
J
Lin
D002966:Clathrin / Q000378:metabolism; D004705:Endocytosis; D021962:Membrane Microdomains / Q000378:metabolism; D059828:Plant Cells / Q000378:metabolism; D010940:Plant Proteins / Q000378:metabolism; D010944:Plants / Q000378:metabolism*
D002966:Clathrin; D010940:Plant Proteins
ESCRT; clathrin; endocytosis; membrane microdomain; regulators