title: Non-adherence to anti-tuberculosis treatment among internal migrants with pulmonary tuberculosis in Shenzhen, China: a cross-sectional study.
abstract: BACKGROUND
  Non-adherence to tuberculosis (TB) treatment threatens the success of treatment, increases the risk of TB spread, and leads to the development of drug resistance. The present study assessed non-adherence to anti-TB treatment among internal migrants with pulmonary TB living in Shenzhen, China, and examined risk factors for non-adherence in order to identify targets for intervention.
  
  
  METHODS
  A total of 794 internal migrants with TB treated at Bao'an Hospital for Chronic Disease Prevention and Cure, Shenzhen, were recruited. Structured questionnaires were used to collect data on these patients' history and experiences with TB treatment. Ordinal logistic regression model were used to identify risk factors for non-adherence.
  
  
  RESULTS
  The proportion of patients who had missed one dose of medication within two weeks was 93/794 (11.71%), and those who missed at least two doses of medication within two weeks was 167/794 (21.03%), with a total of 33.74% of patients not adhering to TB treatment. Lack of knowledge about TB treatment and longer travel time to the nearest community health centers are significant predictors for non-adherence.
  
  
  CONCLUSIONS
  The present study shows that non-adherence is common among internal migrants with TB. Patients who lack knowledge about TB treatment or have to travel far to get treated are prone to miss one or more doses of medication. Interventions to improve health education and healthcare access are essential to reduce non-adherence to TB treatment among internal migrants.
authors.affiliation: Department of Tuberculosis Prevention and Cure, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. 85804139@qq.com.|Bao'an District Key Medical Department of Tuberculosis prevention and control, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. 85804139@qq.com.
authors.forename: Ying
authors.initials: Y
authors.lastname: Tang
authors.affiliation: Department of Tuberculosis Prevention and Cure, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. bazmg@126.com.|Bao'an District Key Medical Department of Tuberculosis prevention and control, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. bazmg@126.com.
authors.forename: Meigui
authors.initials: M
authors.lastname: Zhao
authors.affiliation: Department of Tuberculosis Prevention and Cure, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. yunxia_wang@sina.com.|Bao'an District Key Medical Department of Tuberculosis prevention and control, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. yunxia_wang@sina.com.
authors.forename: Yunxia
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China. gonganhong@163.com.
authors.forename: Yanhong
authors.initials: Y
authors.lastname: Gong
authors.affiliation: Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China. hnyinxiaoxv@126.com.
authors.forename: Xiaoxv
authors.initials: X
authors.lastname: Yin
authors.affiliation: Department of Tuberculosis Prevention and Cure, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. 110637051@qq.com.|Bao'an District Key Medical Department of Tuberculosis prevention and control, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. 110637051@qq.com.
authors.forename: Angui
authors.initials: A
authors.lastname: Zhao
authors.affiliation: Department of Tuberculosis Prevention and Cure, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. 779486428@qq.com.|Bao'an District Key Medical Department of Tuberculosis prevention and control, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. 779486428@qq.com.
authors.forename: Juanjuan
authors.initials: J
authors.lastname: Zheng
authors.affiliation: Department of Tuberculosis Prevention and Cure, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. 1656411050@qq.com.|Bao'an District Key Medical Department of Tuberculosis prevention and control, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. 1656411050@qq.com.
authors.forename: Zhenyang
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Department of Tuberculosis Prevention and Cure, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. 82759120@qq.com.|Bao'an District Key Medical Department of Tuberculosis prevention and control, Bao'an District Hospital for Chronic Diseases Prevention and Cure, Shenzhen, Guangdong, 518101, People's Republic of China. 82759120@qq.com.
authors.forename: Xiaofang
authors.initials: X
authors.lastname: Jian
authors.affiliation: Department of Public Utilities Management, School of Management, Jiangsu University, Zhenjiang, Jiangsu, 212013, People's Republic of China. 272704841@qq.com.
authors.forename: Wenxin
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China. wuchunmei08@gmail.com.
authors.forename: Chunmei
authors.initials: C
authors.lastname: Wu
authors.affiliation: Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, 430030, People's Republic of China. zuxunlu@yahoo.com.
authors.forename: Zuxun
authors.initials: Z
authors.lastname: Lu
mesh_terms: D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001294:Attitude to Health; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006297:Health Services Accessibility / Q000706:statistics & numerical data; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000706:statistics & numerical data*; D017064:Process Assessment, Health Care / Q000379:methods; D036301:Qualitative Research; D012307:Risk Factors; D014171:Transients and Migrants / Q000706:statistics & numerical data*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents