title: Comparison of amine fluoride and chlorhexidine mouth rinses in the control of plaque and gingivitis--a randomized controlled clinical trial.
abstract: OBJECTIVE
  The objective of this triple blind randomized controlled clinical trial was to compare the efficacy of a mouth rinse containing amine fluoride (AmF) and chlorhexidine in controlling the supragingival plaque accumulation and gingival inflammation during a 4-week period in patients with chronic gingivitis.
  
  
  METHODS
  A total of 30 patients were participated in this study. Fifteen patients were prescribed an AmF-containing mouth rinse and 15 were prescribed a chlorhexidine mouth rinse. Plaque index, gingival index, bleeding index, tooth stain, and tongue stain (TS) were recorded at baseline, 15 days and 1-month. Patients' perception of odor, taste and any discomfort were recorded.
  
  
  RESULTS
  The comparisons between the groups were done using Mann-Whitney U-test. The comparison within the group at different time visits were done using Wilcoxon signed rank test. Both the mouth rinses resulted in a significant decrease in plaque index, gingival index, bleeding index. However, AmF mouth rinse resulted in a statistically significant decrease in bleeding index and gingival index compared to chlorhexidine group. There was no significant difference in tooth stain and TS in both the groups.
  
  
  CONCLUSIONS
  The 4 weeks use of AmF containing mouth rinse is effective in reducing the gingival inflammation and plaque.
authors.affiliation: Department of Periodontics, Chettinad Dental College and Research Institute, Kelambakkam, Kanchipuram District, Karnataka, India.
authors.forename: B Meena
authors.initials: BM
authors.lastname: Priya
authors.forename: Sushama R
authors.initials: SR
authors.lastname: Galgali
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000627:therapeutic use*; D003773:Dental Plaque / Q000188:drug therapy*; D003774:Dental Plaque Index; D005260:Female; D005460:Fluorides, Topical / Q000627:therapeutic use*; D005891:Gingivitis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009067:Mouthwashes / Q000627:therapeutic use*; D010512:Periodontal Index; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000891:Anti-Infective Agents, Local; D005460:Fluorides, Topical; D009067:Mouthwashes; C094808:amine fluoride solution; D002710:Chlorhexidine