title: A non-cross-coupling approach to arene-bridged macrocycles: synthesis, structure, and direct, regioselective functionalization of a cycloparaphenylene fragment.
abstract: A new synthetic strategy that employs a relatively unstrained, 1,4-diketo-bridged macrocycle as a precursor to a strained, 1,4-arene-bridged (bent para-phenylene) macrocycle has been developed. The distorted p-terphenyl nucleus (CPP fragment) of the macrocycle has been characterized by X-ray crystallography, and a direct, regioselective bromination protocol of the macrocyclic system is reported.
authors.affiliation: Department of Chemistry and Biochemistry, Auburn University, Auburn, Alabama 36849, United States.
authors.forename: Nirmal K
authors.initials: NK
authors.lastname: Mitra
authors.affiliation: Department of Chemistry and Biochemistry, Auburn University, Auburn, Alabama 36849, United States.
authors.forename: Rolande
authors.initials: R
authors.lastname: Meudom
authors.affiliation: Department of Chemistry and Biochemistry, Auburn University, Auburn, Alabama 36849, United States.
authors.forename: John D
authors.initials: JD
authors.lastname: Gorden
authors.affiliation: Department of Chemistry and Biochemistry, Auburn University, Auburn, Alabama 36849, United States.
authors.forename: Bradley L
authors.initials: BL
authors.lastname: Merner