title: Postprocessing algorithms to minimize fixed-pattern artifact and reduce trigger jitter in swept source optical coherence tomography.
abstract: We propose methods to align interferograms affected by trigger jitter to a reference interferogram based on the information (amplitude/phase) at a fixed-pattern noise location to reduce residual fixed-pattern noise and improve the phase stability of swept source optical coherence tomography (SS-OCT) systems. One proposed method achieved this by introducing a wavenumber shift (k-shift) in the interferograms of interest and searching for the k-shift that minimized the fixed-pattern noise amplitude. The other method calculated the relative k-shift using the phase information at the residual fixed-pattern noise location. Repeating this wavenumber alignment procedure for all A-lines of interest produced fixed-pattern noise free and phase stable OCT images. A system incorporating these correction routines was used for human retina OCT and Doppler OCT imaging. The results from the two methods were compared, and it was found that the intensity-based method provided better results.
authors.forename: Gangjun
authors.initials: G
authors.lastname: Liu
authors.forename: Ou
authors.initials: O
authors.lastname: Tan
authors.forename: Simon S
authors.initials: SS
authors.lastname: Gao
authors.forename: Alex D
authors.initials: AD
authors.lastname: Pechauer
authors.forename: ByungKun
authors.initials: B
authors.lastname: Lee
authors.forename: Chen D
authors.initials: CD
authors.lastname: Lu
authors.forename: James G
authors.initials: JG
authors.lastname: Fujimoto
authors.forename: David
authors.initials: D
authors.lastname: Huang
mesh_terms: D000465:Algorithms; D016477:Artifacts; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008029:Lighting / Q000379:methods*; D015203:Reproducibility of Results; D012160:Retina / Q000033:anatomy & histology*; D012680:Sensitivity and Specificity; D041623:Tomography, Optical Coherence / Q000379:methods*