title: Mild cognitive impairment: vascular risk factors in community elderly in four cities of Hebei Province, China.
abstract: BACKGROUND
  Evidence has demonstrated that vascular risk factors (VRFs) contribute to mild cognitive impairment (MCI) in the elderly population. Because of the race and different diagnosis standard, there is still no definitive conclusions.
  
  
  OBJECTIVE
  To estimate the VRFs and potential protective factors for MCI in elderly population living in the community in North China.
  
  
  METHODS
  A total of 3136 participants entered the study. They were screened for hypertension, coronary heart disease (CHD), and cerebrovascular disease (CVD). Cognitive function was assessed with Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA). The diagnosis of MCI was made according to Petersen's criteria. We investigated the relationship between vascular risk factors, potential protective factors and MCI.
  
  
  RESULTS
  A total of 2511 (80%) participant belonged to normal group and 625 (20%) participants showed MCI. Multiple logistic regression analysis demonstrated that stroke and diabetes, but not hypertension or CHD was associated with MCI. Besides, exercise habit could lower the risk of MCI.
  
  
  CONCLUSIONS
  Vascular Risk Factors, including stroke and diabetes, rather than hypertension and CHD are independent risk factors of MCI. Involvement in physical activities seems to reduce the risk of MCI.
authors.affiliation: Department of Psychiatry, First Hospital of Hebei Medical University, Shijiazhuang, 050031, China; Mental Health Institute of Hebei Medical University, Shijiazhuang, 050031, China; Brain Aging and Cognitive Neuroscience Laboratory of Hebei Medical University, Shijiazhuang, 050031, China.
authors.forename: Yumei
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Psychiatry, First Hospital of Hebei Medical University, Shijiazhuang, 050031, China; Mental Health Institute of Hebei Medical University, Shijiazhuang, 050031, China; Brain Aging and Cognitive Neuroscience Laboratory of Hebei Medical University, Shijiazhuang, 050031, China.
authors.forename: Mei
authors.initials: M
authors.lastname: Song
authors.affiliation: Department of Psychiatry, First Hospital of Hebei Medical University, Shijiazhuang, 050031, China; Mental Health Institute of Hebei Medical University, Shijiazhuang, 050031, China.
authors.forename: Lulu
authors.initials: L
authors.lastname: Yu
authors.affiliation: Department of Psychiatry, First Hospital of Hebei Medical University, Shijiazhuang, 050031, China; Mental Health Institute of Hebei Medical University, Shijiazhuang, 050031, China; Brain Aging and Cognitive Neuroscience Laboratory of Hebei Medical University, Shijiazhuang, 050031, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Psychiatry, First Hospital of Hebei Medical University, Shijiazhuang, 050031, China; Mental Health Institute of Hebei Medical University, Shijiazhuang, 050031, China; Brain Aging and Cognitive Neuroscience Laboratory of Hebei Medical University, Shijiazhuang, 050031, China.
authors.forename: Cuixia
authors.initials: C
authors.lastname: An
authors.affiliation: Department of Psychiatry, First Hospital of Hebei Medical University, Shijiazhuang, 050031, China; Mental Health Institute of Hebei Medical University, Shijiazhuang, 050031, China; Brain Aging and Cognitive Neuroscience Laboratory of Hebei Medical University, Shijiazhuang, 050031, China.
authors.forename: Shunjiang
authors.initials: S
authors.lastname: Xun
authors.affiliation: Department of Psychiatry, First Hospital of Hebei Medical University, Shijiazhuang, 050031, China; Mental Health Institute of Hebei Medical University, Shijiazhuang, 050031, China; Brain Aging and Cognitive Neuroscience Laboratory of Hebei Medical University, Shijiazhuang, 050031, China.
authors.forename: Xiaochuan
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Department of Psychiatry, First Hospital of Hebei Medical University, Shijiazhuang, 050031, China; Mental Health Institute of Hebei Medical University, Shijiazhuang, 050031, China; Brain Aging and Cognitive Neuroscience Laboratory of Hebei Medical University, Shijiazhuang, 050031, China.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Department of Psychiatry, First Hospital of Hebei Medical University, Shijiazhuang, 050031, China; Mental Health Institute of Hebei Medical University, Shijiazhuang, 050031, China; Brain Aging and Cognitive Neuroscience Laboratory of Hebei Medical University, Shijiazhuang, 050031, China.
authors.forename: Xueyi
authors.initials: X
authors.lastname: Wang
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000453:epidemiology; D002681:China / Q000453:epidemiology; D002947:Cities; D060825:Cognitive Dysfunction / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D062486:Public Health Surveillance; D012307:Risk Factors; D011795:Surveys and Questionnaires