title: The effect of valeric on anxiety severity in women undergoing hysterosalpingography.
abstract: Hysterosalpingography (HSG) is the radiographic evaluation of the uterine cavity and fallopian tubes, which is generally assumed as a stressful and painful procedure. This study aims to determine effect of oral Valeric capsules on anxiety severity in women under Hysterosalpingography.
  This study, as a double-blind clinical trial, was conducted on 64 infertile women undergoing hysterosalpingography, who referred to radiology ward at Comprehensive Women's hospital. To measure anxiety, visual analog anxiety scale was used 90 minutes before starting procedure, individuals in intervention group (n=32) received a single dose (1,500 mg) of 3 Valeric capsules, together with routine prophylaxy, where routine prophylaxis contains Mefenamic acid 250mg capsules in 30 minutes before procedure, and the same capsules were prescribed to placebo group (n=32) with the same instruction. Anxiety severity before and once 90 minutes after intervention in both groups were measured and compared.
  
  
  RESULTS
  There was no difference on anxiety severity before intervention in both groups (p=0.26), and the groups were homogeneous; after intervention, a significant difference on anxiety severity was reported in both groups (p<0/0001), and anxiety score in intervention group compared to placebo reduced statistically.
  
  
  CONCLUSIONS
  Present study indicated that Valeric was effective on reducing anxiety in women undergoing hysterosalpingography.
authors.affiliation: . gjhs@ccsenet.org.
authors.forename: Maryam
authors.initials: M
authors.lastname: Gharib
authors.forename: Leila Neisani
authors.initials: LN
authors.lastname: Samani
authors.forename: Zahra Elahi
authors.initials: ZE
authors.lastname: Panah
authors.forename: Mohsen
authors.initials: M
authors.lastname: Naseri
authors.forename: Naser
authors.initials: N
authors.lastname: Bahrani
authors.forename: Kiandokht
authors.initials: K
authors.lastname: Kiani
mesh_terms: D000328:Adult; D000700:Analgesics / Q000627:therapeutic use*; D001007:Anxiety / Q000188:drug therapy* / Q000209:etiology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007047:Hysterosalpingography / Q000009:adverse effects*; D007247:Infertility, Female; D008528:Mefenamic Acid / Q000627:therapeutic use; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D012720:Severity of Illness Index; D014632:Valerian
chemical_list: D000700:Analgesics; D008528:Mefenamic Acid