title: VALIDATION OF AN ALGORITHM FOR NONMETALLIC INTRAOCULAR FOREIGN BODIES' COMPOSITION IDENTIFICATION BASED ON COMPUTED TOMOGRAPHY AND MAGNETIC RESONANCE IMAGING.
abstract: OBJECTIVE
  To validate and evaluate the accuracy of an algorithm for the identification of nonmetallic intraocular foreign body composition based on computed tomography and magnetic resonance imaging.
  
  
  METHODS
  An algorithm for the identification of 10 nonmetallic materials based on computed tomography and magnetic resonance imaging has been previously determined in an ex vivo porcine model. Materials were classified into 4 groups (plastic, glass, stone, and wood). The algorithm was tested by 40 ophthalmologists, which completed a questionnaire including 10 sets of computed tomography and magnetic resonance images of eyes with intraocular foreign bodies and were asked to use the algorithm to identify their compositions. Rates of exact material identification and group identification were measured.
  
  
  RESULTS
  Exact material identification was achieved in 42.75% of the cases, and correct group identification in 65%. Using the algorithm, 6 of the materials were exactly identified by over 50% of the participants, and 7 were correctly classified according to their groups by over 75% of the materials.
  
  
  CONCLUSIONS
  The algorithm was validated and was found to enable correct identification of nonmetallic intraocular foreign body composition in the majority of cases. This is the first study to report and validate a clinical tool allowing intraocular foreign body composition based on their appearance in computed tomography and magnetic resonance imaging, which was previously impossible.
authors.affiliation: *Department of Ophthalmology, Tel Aviv Medical Center, Tel Aviv, Israel; †Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel; ‡The Galilee Faculty of Medicine, The Bar-Ilan University, Ramat Gan, Israel; §The Advanced Technology Center, Sheba Medical Center, Tel-Hashomer, Israel; and ¶Department of Ophthalmology, West Galilee Hospital, Nahariya, Israel.
authors.forename: Elad
authors.initials: E
authors.lastname: Moisseiev
authors.forename: Dana
authors.initials: D
authors.lastname: Barequet
authors.forename: Eran
authors.initials: E
authors.lastname: Zunz
authors.forename: Adiel
authors.initials: A
authors.lastname: Barak
authors.forename: Yael
authors.initials: Y
authors.lastname: Mardor
authors.forename: David
authors.initials: D
authors.lastname: Last
authors.forename: David
authors.initials: D
authors.lastname: Goez
authors.forename: Zvi
authors.initials: Z
authors.lastname: Segal
authors.forename: Anat
authors.initials: A
authors.lastname: Loewenstein
mesh_terms: D000465:Algorithms; D000818:Animals; D004195:Disease Models, Animal; D015353:Eye Enucleation; D005129:Eye Foreign Bodies / Q000175:diagnosis* / Q000000981:diagnostic imaging; D015807:Eye Injuries, Penetrating / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005260:Female; D019015:Geologic Sediments; D005898:Glass; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010969:Plastics; D011795:Surveys and Questionnaires; D034421:Sus scrofa; D014057:Tomography, X-Ray Computed; D014934:Wood
chemical_list: D010969:Plastics