title: Effects of Maternal Linseed Oil Supplementation on Metabolic Parameters in Cafeteria Diet-induced Obese Rats.
abstract: Because linseed oil may influence maternal and fetal metabolisms, we investigated its role in the modulation of lipid metabolism in cafeteria diet-induced obese rats and their offspring. Female Wistar rats were fed control or cafeteria food, which were either supplemented or not supplemented with linseed oil (5%) for 1 month before and during gestation. At parturition, serum and tissue lipids and enzyme activities were analyzed. Cafeteria diet induced adverse metabolic alterations in both mothers and offspring. Linseed oil improved metabolic status. In conclusion, linseed oil displayed health benefits by modulating tissue enzyme activities in both obese mothers and their newborns.
authors.affiliation: Laboratory of Physiology and Biochemistry of Nutrition, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, University Abou-Bekr Belkaïd, Tlemcen 13000, Algeria.
authors.forename: Nawel
authors.initials: N
authors.lastname: Benaissa
authors.affiliation: Laboratory of Physiology and Biochemistry of Nutrition, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, University Abou-Bekr Belkaïd, Tlemcen 13000, Algeria.
authors.forename: Hafida
authors.initials: H
authors.lastname: Merzouk
authors.affiliation: Department of technical Sciences, Faculty of Engineering, University Abou-Bekr Belkaïd, Tlemcen 13000, Algeria.
authors.forename: Sid Ahmed
authors.initials: SA
authors.lastname: Merzouk
authors.affiliation: INSERM UMR 866, 'Lipids Nutrition Cancer', University of Burgundy, Faculty of Sciences, 6 Boulevard Gabriel, Dijon 21000, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Narce
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000818:Animals; D004032:Diet / Q000009:adverse effects*; D019587:Dietary Supplements / Q000032:analysis; D005260:Female; D008043:Linseed Oil / Q000008:administration & dosage / Q000378:metabolism*; D050356:Lipid Metabolism / Q000187:drug effects*; D039382:Maternal Nutritional Physiological Phenomena / Q000187:drug effects; D009765:Obesity / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D011897:Random Allocation; D051381:Rats; D017208:Rats, Wistar
chemical_list: D008043:Linseed Oil