title: [Radiation-induced DNA fragmentation in cells of somatic and generative tissues of Drosophila melanogaster].
abstract: The levels of DNA fragmentation (using a neutral version of the "Comet assay" method) in the cells of somatic (brain ganglia) and generative (male gonad) tissues of the inbred individuals of the Drosophila wild-type developing in different conditions of a chronic irradiation were estimated. It was found that the radiobiological effect depends on the genotype and cytotype. Irradiation at low doses (0.42 mGy/h) induces the DNA damage in somatic cells of all the studied lines Drosophila in the same way. With the increase in the intensity of chronic irradiation (3.5mGy/h) a significant level of DNA breaks in neuroblasts was observed only for Harwich and Oregon-R stocks, in the cells of male gonad--for all the studied genotypes.
authors.forename: E
authors.initials: E
authors.lastname: Yushkova
authors.forename: V
authors.initials: V
authors.lastname: Zainullin
mesh_terms: D000818:Animals; D004249:DNA Damage / Q000528:radiation effects*; D053938:DNA Fragmentation / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D004331:Drosophila melanogaster / Q000235:genetics / Q000528:radiation effects*; D005720:Gamma Rays; D005724:Ganglia / Q000528:radiation effects; D006066:Gonads / Q000528:radiation effects; D011836:Radiation Tolerance / Q000235:genetics*