title: Mast cell and autoimmune diseases.
abstract: Mast cells are important in innate immune system. They have been appreciated as potent contributors to allergic reaction. However, increasing evidence implicates the important role of mast cells in autoimmune disease like rheumatoid arthritis and multiple sclerosis. Here we review the current stage of knowledge about mast cells in autoimmune diseases.
authors.affiliation: Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Immunology, Shanghai 200025, China.
authors.forename: Yunzhi
authors.initials: Y
authors.lastname: Xu
authors.affiliation: Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Immunology, Shanghai 200025, China.
authors.forename: Guangjie
authors.initials: G
authors.lastname: Chen
mesh_terms: D000818:Animals; D001172:Arthritis, Rheumatoid / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology*; D002465:Cell Movement; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology; D004791:Enzyme Inhibitors / Q000737:chemistry; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology; D007113:Immunity, Innate; D007249:Inflammation / Q000276:immunology; D008407:Mast Cells / Q000276:immunology*; D051379:Mice; D008822:Mice, Transgenic; D009103:Multiple Sclerosis / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000166:cytology; D058504:Th17 Cells / Q000166:cytology; D014581:Urticaria / Q000276:immunology
chemical_list: D004791:Enzyme Inhibitors