title: [Eczema herpeticum in a patient with atopic dermatitis, carrying r501x and 2282del4 filaggrin null mutations].
abstract: Eczema herpeticum is an acute dermatoses caused by herpes simplex virus type 1 in atopic dermatitis patients, and is considered a dermatology emergency. Eczema herpeticum occurs in less than 3% of atopic patients. We report a patient with a history of atopic dermatitis who presented to an emergency department with eczema herpeticum. He was admitted and treated with antiviral medications with good outcome. We investigated filaggrin null mutations in the patient and his family and correlate them with the severity of the disease. We present the first Mexican patient with eczema herpeticum, atopic dermatitis and the presence of R501 X and 2282del4 filaggrin null mutations.
authors.affiliation: Departamento de Dermatología, Temple University, School of Medicine, Filadelfia, USA.
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Valdés-Rodríguez
authors.affiliation: Departamento de Bioquímica, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, S.L.P, Mexico.
authors.forename: Víctor M
authors.initials: VM
authors.lastname: Saavedra-Alanís
authors.affiliation: Departamento de Bioquímica, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí, S.L.P, Mexico.
authors.forename: Mario A
authors.initials: MA
authors.lastname: Islas-Aguilar
authors.affiliation: Departamento de Dermatología, Hospital Central «Dr. Ignacio Morones Prieto», Universidad Autónoma de San Luis Potosí, San Luis Potosí, S.L.P., Mexico.
authors.forename: Bertha
authors.initials: B
authors.lastname: Torres-Álvarez
mesh_terms: D000293:Adolescent; D003876:Dermatitis, Atopic / Q000150:complications* / Q000235:genetics*; D000091344:Filaggrin Proteins; D006801:Humans; D007381:Intermediate Filament Proteins / Q000235:genetics*; D007617:Kaposi Varicelliform Eruption / Q000150:complications*; D008297:Male; D009154:Mutation; D010375:Pedigree
chemical_list: C000717249:FLG protein, human; D000091344:Filaggrin Proteins; D007381:Intermediate Filament Proteins