title: Primary leiomyosarcoma of the maxilla: An investigative loom-report of a challenging case and review of literature.
abstract: Leiomyosarcoma (LMS) is a malignant neoplasm composed of cells showing distinct smooth muscle features. Majority of the tumors are located in the retroperitoneum, including the pelvis and the uterus but are rare in the oral and pharyngeal region. Intraorally, they are present as painless, lobulated, fixed masses of the submucosal tissues in middle-aged or older individuals. Lesions are usually slow growing and are less than 2 cm in diameter at the time of diagnosis. Here we report the clinico-pathological findings of a case of primary LMS of the maxilla in 63-year-old male patient with an emphasis on the judicious use of ancillary diagnostic modalities to arrive at a definitive diagnosis.
authors.affiliation: Department of Oral and Maxillofacial Pathology, Genesis Institute of Dental Sciences and Research, Ferozepur, India.
authors.forename: Simarpreet Virk
authors.initials: SV
authors.lastname: Sandhu
authors.affiliation: Department of Oral and Maxillofacial Surgery, Dashmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India.
authors.forename: S P S
authors.initials: SP
authors.lastname: Sodhi
authors.affiliation: Department of Oral and Maxillofacial Surgery, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Sachin
authors.initials: S
authors.lastname: Rai
authors.affiliation: Department of Oral and Maxillofacial Pathology, Genesis Institute of Dental Sciences and Research, Ferozepur, India.
authors.forename: Himanta
authors.initials: H
authors.lastname: Bansal
keywords: Leiomyosarcoma; malignant spindle cell tumor; nuclear palisading; pleomorphic undifferentiated sarcoma; rhabdomyosarcoma; soft tissue sarcoma