title: Use of a New Hybrid Heparin-Bonded Nitinol Ring Stent in the Popliteal Artery: Procedural and Mid-term Clinical and Anatomical Outcomes.
abstract: OBJECTIVE
  To report the immediate and mid-term clinical and anatomical outcomes of a novel, hybrid, heparin-bonded, nitinol ring stent (TIGRIS; Gore Medical) when used for the treatment of lesions located in the popliteal artery.
  
  
  METHODS
  This was a prospective single-centre registry. Patients eligible for inclusion were individuals suffering from symptomatic popliteal arterial occlusive disease (Rutherford-Becker stage 3-6; P1-P3 segments) and treated with placement of the TIGRIS stent(s). Patients were prospectively scheduled for clinical review and duplex ultrasound follow-up after 6 and 12 months. Outcome measures included immediate technical success, primary vessel patency, in-stent binary restenosis (evaluable by Duplex at 50 % threshold; PSVR > 2.0), freedom from target lesion revascularization (TLR) and amputation-free survival (AFS) estimated by Kaplan-Meier (K-M) survival analysis. Cox proportional-hazards regression analysis was also performed to adjust for confounders and search for independent predictors of outcomes.
  
  
  RESULTS
  From August 2012 to March 2014, a total of 54 popliteal TIGRIS stents were implanted in 50 limbs of 48 patients (27 men and 21 women; mean age 76.0 ± 1.7 years). Median Rutherford-Becker stage was five at baseline and 37/50 (74.0%) were chronic total occlusions. Technical success was achieved in all cases (100%). Stented lesion length was 114.2 ± 36.9 mm (range 6-20 cm). Median follow-up was 11.8 ± 0.8 months. After 12 months, primary patency of the TIGRIS stent was 69.5 ± 10.2% with an 86.1 ± 5.9% freedom from TLR and 87 ± 5.0% AFS (K-M estimates).
  
  
  CONCLUSIONS
  The TIGRIS hybrid heparin-bonded nitinol ring stent is a safe and effective endovascular option for complex occlusive disease of the popliteal artery.
authors.affiliation: Department of Interventional Radiology, Guy's and St. Thomas' Hospitals, NHS Foundation Trust, King's Health Partners, London, SE1 7EH, UK.
authors.forename: Aneeta
authors.initials: A
authors.lastname: Parthipun
authors.forename: Athanasios
authors.initials: A
authors.lastname: Diamantopoulos
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Kitrou
authors.forename: Soundrie
authors.initials: S
authors.lastname: Padayachee
authors.forename: Narayan
authors.initials: N
authors.lastname: Karunanithy
authors.forename: Irfan
authors.initials: I
authors.lastname: Ahmed
authors.forename: Hany
authors.initials: H
authors.lastname: Zayed
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Katsanos
mesh_terms: D000368:Aged; D000497:Alloys; D000925:Anticoagulants / Q000008:administration & dosage; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D011150:Popliteal Artery / Q000033:anatomy & histology* / Q000000981:diagnostic imaging / Q000601:surgery*; D016016:Proportional Hazards Models; D011446:Prospective Studies; D011474:Prosthesis Design; D015641:Radiography, Interventional; D015607:Stents; D016896:Treatment Outcome; D014654:Vascular Patency
chemical_list: D000497:Alloys; D000925:Anticoagulants; C013616:nitinol; D006493:Heparin