title: A meta-analysis of surgical success rates in congenital stapes fixation and juvenile otosclerosis.
abstract: OBJECTIVE
  To assess published reports in the literature on surgical success rates in patients with congenital stapes fixation (CSF) and juvenile otosclerosis (JO).
  
  
  METHODS
  Systematic review of the literature and meta-analysis of published data.
  
  
  METHODS
  PubMed, SAGE, MEDLINE, and Cochrane.
  
  
  METHODS
  A literature search was performed and evaluated based on established criteria. Two independent reviewers (b.a., m.b.) inspected titles and abstracts of the studies. The full texts of the studies were examined to assess their relevance to the meta-analysis. An air-bone gap (ABG) of 0 to 10 dB hearing level was described as success of surgery.
  
  
  RESULTS
  A random effects model was used to analyze the data. A total of 27 studies were included in the meta-analysis, whereas 934 were excluded. The total number of operated ears was 445 (256 ears with JO and 189 ears with CSF). At the time of surgery, the age of the patients ranged from 3 to 18 years. The success rate was 80.2% for JO and 54% for CSF. The overall success rate was 69.9%. The rate of postoperative sensorineural hearing loss was 3.4% for JO and 2.1% for CSF.
  
  
  CONCLUSIONS
  Overall, stapes surgery in children with JO or CSF has a moderate success rate (69.9%) to provide ABG closure of 10 dB. The success rate for CSF in the setting of ossicular abnormalities is 54%. This meta-analysis suggests that if JO can be determined before surgery, a higher success rate is possible (80.2%).
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Asik
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Binar
authors.affiliation: Department of Medical Biochemistery, Acibadem University School of Medicine, Istanbul, Turkey.
authors.forename: Muhittin
authors.initials: M
authors.lastname: Serdar
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Satar
mesh_terms: D002648:Child; D006801:Humans; D010040:Otosclerosis / Q000601:surgery*; D010043:Outcome and Process Assessment, Health Care; D013201:Stapes Surgery
keywords: Congenital stapes fixation; juvenile otosclerosis; stapedectomy; stapedotomy; success rate