title: Synthesis of 4(3H)quinazolinimines by reaction of (E)-N-(aryl)-acetimidoyl or -benzimidoyl chloride with amines.
abstract: An efficient one-step method to access 4(3H)quinazolinimines by reaction of phenylchloroimines with 2-aminobenzonitrile is described. The reaction of (E)-N-(2-cyanophenyl)benzimidoyl chloride with substituted anilines that yields a number of their corresponding C2, N3-substituted quinazoliniminium chlorides or neutral products is also reported. These methods provide direct and flexible access to diverse substituted iminoquinazolines substituted at the C2, N3-positions. All the new compounds were fully characterized and six examples are given with their single-crystal X-ray structure.
authors.affiliation: Departamento de Química Inorgánica, Facultad de Química, Pontificia Universidad Católica de Chile, Casilla 306, Santiago-22, Chile. rrojasg@uc.cl.
authors.forename: Celso
authors.initials: C
authors.lastname: Quintero
authors.forename: Mauricio
authors.initials: M
authors.lastname: Valderrama
authors.forename: Alexandra
authors.initials: A
authors.lastname: Becerra
authors.forename: Constantin G
authors.initials: CG
authors.lastname: Daniliuc
authors.forename: Rene S
authors.initials: RS
authors.lastname: Rojas
mesh_terms: D000588:Amines / Q000737:chemistry*; D001562:Benzimidazoles / Q000737:chemistry*; D007097:Imines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000588:Amines; D001562:Benzimidazoles; D007097:Imines; D009570:Nitriles; D011799:Quinazolines