title: Clinical performance of topical sodium fluoride when supplementing carbamide peroxide at-home bleaching gel.
abstract: This clinical study evaluated the use of 0.11% topical sodium fluoride (SF) desensitizing agent to treat tooth sensitivity during a nightguard tooth whitening procedure. Thirty-two subjects bleached their teeth with 10% carbamide peroxide (CP) gel using an at-home bleaching technique with custom trays. During bleaching treatment, subjects were divided into 2 groups (n = 16). The subjects in Group 1 received a topical gel containing 0.11% SF; the subjects in Group 2 received a placebo gel (PG). Each subject was instructed to place the gel in his/her bleaching tray for 30 min every day following bleaching treatment. Results showed the use of SF did not affect the whitening efficacy of the 10% CP gel. Subjects who received the PG had significantly higher tooth sensitivity when compared with subjects who received SF (P < 0.00). The use of daily 0.11% SF after 10% CP bleaching gel reduced tooth sensitivity during the bleaching treatment.
authors.forename: Daphne Camara
authors.initials: DC
authors.lastname: Barcellos
authors.forename: Graziela Ribeiro
authors.initials: GR
authors.lastname: Batista
authors.forename: Melissa Aline
authors.initials: MA
authors.lastname: da Silva
authors.forename: Patricia Rondon
authors.initials: PR
authors.lastname: Pleffken
authors.forename: Marcia Carneiro
authors.initials: MC
authors.lastname: Valera
mesh_terms: D000287:Administration, Topical; D000077463:Carbamide Peroxide; D057133:Dentin Desensitizing Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000517:prevention & control*; D005260:Female; D005782:Gels; D006801:Humans; D008297:Male; D010545:Peroxides / Q000627:therapeutic use*; D012648:Self Care / Q000379:methods; D012969:Sodium Fluoride / Q000008:administration & dosage / Q000627:therapeutic use*; D014073:Tooth Bleaching / Q000379:methods*; D058205:Tooth Bleaching Agents / Q000627:therapeutic use*; D014508:Urea / Q000031:analogs & derivatives* / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D057133:Dentin Desensitizing Agents; D005782:Gels; D010545:Peroxides; D058205:Tooth Bleaching Agents; D000077463:Carbamide Peroxide; D014508:Urea; D012969:Sodium Fluoride
keywords: carbamide peroxide; dental bleaching; fluoride; tooth sensitivity