title: [Comparison of diagnostic quality in hysterosalpingography between iodinated non-ionic contrast media with low and high osmolarity].
abstract: Comparison of diagnostic quality in hysterosalpingography between low and high-osmolality contrast media.
  
  
  
  We performed a retrospective evaluation of two cohorts of patients who underwent HSG using contrast media with different osmolarity: the first group ,47 patients, underwent hysterosalpingography in the period September 2011-December 2012 using Iopromide 370 mg/ml; the second group, 50 patients, underwent HSG from January 2013 to October 2013 using Iomeprol 400 mg/ml. Three radiologists, in consensus reading,, reviewed the radiographs by assessing the following four parameters: opacification of the uterine cavity, uterine profiles definition, Fallopian tubes visualization, contrast media spillage into peritoneum. A score-scale from 0 to 3 was assigned for each of the mentioned parameter (0 = minimum non-diagnostic exam, 1 = sufficient examination; 2 = good quality examination; maximum 3 = high quality images).
  
  
  
  We documented a statistically significant higher quality in displaying Fallopian tubes among patients studied through high osmolarity contrast medium (Iopromide 370 mg/ml) than what obtained through lower osmolarity contrast medium (Iomeprol 400 mg/ml).
  
  
  
  The use of high osmolarity contrast medium enabled better visualization of the tubes and a greater number of diagnoses of chronic aspecific salpigintis due to the increased osmolality and viscosity of Iomeprol 400 mg/ml. There were no significant differences between the two contrast agents in the evaluation of intra-uterine pathology and in the evaluation of the tubal patency.
authors.affiliation: Dipartimento di Diagnostica per Immagini, Ospedale Sant'Andrea. Facoltà di Medicina e Psicologia, Università degli Studi di Roma "Sapienza", Roma, Italia.
authors.forename: K
authors.initials: K
authors.lastname: Piccotti
authors.affiliation: Dipartimento di Diagnostica per Immagini, Ospedale Sant'Andrea. Facoltà di Medicina e Psicologia, Università degli Studi di Roma "Sapienza", Roma, Italia.
authors.forename: D
authors.initials: D
authors.lastname: Guida
authors.affiliation: Dipartimento di Diagnostica per Immagini, Ospedale Sant'Andrea. Facoltà di Medicina e Psicologia, Università degli Studi di Roma "Sapienza", Roma, Italia.
authors.forename: F
authors.initials: F
authors.lastname: Carbonetti
authors.affiliation: Dipartimento di Diagnostica per Immagini, Ospedale Sant'Andrea. Facoltà di Medicina e Psicologia, Università degli Studi di Roma "Sapienza", Roma, Italia.
authors.forename: L
authors.initials: L
authors.lastname: Stefanetti
authors.affiliation: Dipartimento di Diagnostica per Immagini, Ospedale Sant'Andrea. Facoltà di Medicina e Psicologia, Università degli Studi di Roma "Sapienza", Roma, Italia.
authors.forename: A
authors.initials: A
authors.lastname: Macioce
authors.affiliation: Dipartimento di Diagnostica per Immagini, Ospedale Sant'Andrea. Facoltà di Medicina e Psicologia, Università degli Studi di Roma "Sapienza", Roma, Italia.
authors.forename: A
authors.initials: A
authors.lastname: Cremona
authors.affiliation: Dipartimento di Diagnostica per Immagini, Ospedale Sant'Andrea. Facoltà di Medicina e Psicologia, Università degli Studi di Roma "Sapienza", Roma, Italia.
authors.forename: V
authors.initials: V
authors.lastname: David
mesh_terms: D003287:Contrast Media / Q000008:administration & dosage / Q000737:chemistry*; D005260:Female; D006801:Humans; D007047:Hysterosalpingography; D007472:Iohexol / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000737:chemistry; D007479:Iopamidol / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000737:chemistry; D009994:Osmolar Concentration; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media; C057937:iomeprol; D007472:Iohexol; C038192:iopromide; D007479:Iopamidol
keywords: Contrast media; Hysterosalpingography; Infertility; Tubal pathology