title: Is seven the minimum number of water molecules per ion pair for assured biological activity in ionic liquid-water mixtures?
abstract: Ionic liquids (ILs) containing small amounts of water are called hydrated ILs and they show diverse physico-chemical properties that are strongly dependent on their water content. Some properties of hydrated ILs, such as biological activity and phase transition behaviour, were found to change non-linearly, with an inflection at a water molecule to ion pair ratio of around 7:1. This critical hydration number of ILs has been discussed in this paper with respect to the state of solvated water molecules.
authors.affiliation: Department of Biotechnology, Tokyo University of Agriculture and Technology, 2-24-16 Nakacho, Koganei, Tokyo 184-8588, Japan. ohnoh@cc.tuat.ac.jp.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ohno
authors.forename: Kyoko
authors.initials: K
authors.lastname: Fujita
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kohno
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D045424:Complex Mixtures / Q000737:chemistry; D003198:Computer Simulation; D052578:Ionic Liquids / Q000737:chemistry*; D007477:Ions / Q000737:chemistry*; D008422:Materials Testing; D008954:Models, Biological; D008956:Models, Chemical; D062105:Molecular Docking Simulation; D013329:Structure-Activity Relationship; D014867:Water / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D045424:Complex Mixtures; D052578:Ionic Liquids; D007477:Ions; D014867:Water