title: A hybrid named entity tagger for tagging human proteins/genes.
abstract: The predominant step and pre-requisite in the analysis of scientific literature is the extraction of gene/protein names in biomedical texts. Though many taggers are available for this Named Entity Recognition (NER) task, we found none of them achieve a good state-of-art tagging for human genes/proteins. As most of the current text mining research is related to human literature, a good tagger to precisely tag human genes and proteins is highly desirable. In this paper, we propose a new hybrid approach based on (a) machine learning algorithm (conditional random fields), (b) set of (manually constructed) rules, and (c) a novel abbreviation identification algorithm to surmount the common errors observed in available taggers to tag human genes/proteins. Experiment results on JNLPBA2004 corpus show that our domain specific approach achieves a high precision of 80.47, F-score of 75.77 and outperforms most of the state-of-the-art systems. However, the recall of 71.60 still remains low and leaves much room for future improvement.
authors.forename: Kalpana
authors.initials: K
authors.lastname: Raja
authors.forename: Suresh
authors.initials: S
authors.lastname: Subramani
authors.forename: Jeyakumar
authors.initials: J
authors.lastname: Natarajan
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D019295:Computational Biology / Q000379:methods*; D057225:Data Mining; D016208:Databases, Factual; D005796:Genes; D006801:Humans; D015233:Models, Statistical; D011506:Proteins / Q000737:chemistry*; D015203:Reproducibility of Results; D018875:Vocabulary, Controlled
chemical_list: D011506:Proteins