title: Retinal angiomatous proliferation in an eye with cuticular drusen.
abstract: OBJECTIVE
  To report the presence of retinal angiomatous proliferation (RAP) in an eye with cuticular drusen detected by fluorescein and indocyanine green angiography by confocal scanning laser ophthalmoscopy and by spectral-domain optical coherence tomography (SD-OCT).
  
  
  METHODS
  Case report of a 65-year-old Japanese woman with cuticular drusen.
  
  
  RESULTS
  At her first ophthalmic examination, her visual acuity was 20/20 in both eyes. An ophthalmoscopy showed many small subretinal pigment epithelial deposits in both eyes. These deposits had a 'saw-tooth pattern' in the SD-OCT images. During the follow-up examination, retinal hemorrhages were observed, and fluorescein angiography showed a 'stars-in-the-sky' appearance and intraretinal neovascularization. The patient was diagnosed with cuticular drusen associated with RAP.
  
  
  CONCLUSIONS
  We suggest that the cuticular drusen were associated with RAP, so periodic follow-up examinations are needed for patients with cuticular drusen for the early detection and treatment of RAP.
authors.affiliation: Department of Ophthalmology, Matsumoto Dental University, Shiojiri, Japan.
authors.forename: Atsuko
authors.initials: A
authors.lastname: Sato
authors.affiliation: Department of Ophthalmology, Matsumoto Dental University, Shiojiri, Japan.
authors.forename: Nami
authors.initials: N
authors.lastname: Senda
authors.affiliation: Department of Ophthalmology, Matsumoto Dental University, Shiojiri, Japan.
authors.forename: Emi
authors.initials: E
authors.lastname: Fukui
authors.affiliation: Department of Ophthalmology, Matsumoto Dental University, Shiojiri, Japan.
authors.forename: Kouichi
authors.initials: K
authors.lastname: Ohta
keywords: Basal laminar drusen; Cuticular drusen; Retinal angiomatous proliferation; Spectral domain optical coherence tomography