title: Adult-onset Still's disease associated with collapsing glomerulopathy.
abstract: A young woman of African descent presented with fevers, arthralgia, lymphadenopathy and a skin rash. Modest proteinuria was also noted. The clinical picture suggested an acute HIV sero-conversion illness, and a renal biopsy showed a collapsing glomerulopathy compatible with that diagnosis. However, HIV serology proved persistently negative and a diagnosis of Adult Still's disease was subsequently made (by Yamaguchi criteria). Following steroid treatment, the patient's fever abated and her inflammatory markers returned to normal. Collapsing glomerulopathy is a rare but important complication of Adult Still's disease. Immunosuppressive treatment may be effective in improving renal outcome.
authors.affiliation: Department of Renal Medicine , North Middlesex University Hospital , London N18 1QX.
authors.forename: Nishkantha
authors.initials: N
authors.lastname: Arulkumaran
authors.affiliation: Department of Cellular Pathology , Royal Free Hospital , London NW3 2QG , UK.
authors.forename: Pablo
authors.initials: P
authors.lastname: Reitbock
authors.affiliation: Department of Renal Medicine , North Middlesex University Hospital , London N18 1QX.
authors.forename: Kirsty
authors.initials: K
authors.lastname: Halliday
authors.affiliation: Department of Renal Medicine , North Middlesex University Hospital , London N18 1QX.
authors.forename: James
authors.initials: J
authors.lastname: Onwubalili
authors.affiliation: Department of Renal Medicine , North Middlesex University Hospital , London N18 1QX.
authors.forename: Dakshina
authors.initials: D
authors.lastname: Jayasena
authors.affiliation: Department of Renal Medicine , North Middlesex University Hospital , London N18 1QX.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Dupont
keywords: Adult Still’s disease; collapsing glomerulopathy