title: Controlled Synthesis of 1,3,5-Oxadiazin-2-ones and Oxazolones through Regioselective Iodocyclization of Ynamides.
abstract: Two efficient processes based on the iodocyclization of ynamides have been developed: (i) N-alkynyl tert-butyloxycarbamates were found to undergo a rare 6-exo-dig ring closure reaction affording 1,3,5-oxadiazin-2-ones by using acetonitrile as solvent; (ii) In the absence of acetonitrile, N-alkynyl tert-butyloxycarbamates could undergo 5-endo-dig cyclization providing oxazolones.
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, P. R. China.
authors.forename: Hai
authors.initials: H
authors.lastname: Huang
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, P. R. China.
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Zhu
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, P. R. China.
authors.forename: Guangke
authors.initials: G
authors.lastname: He
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, P. R. China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, P. R. China.
authors.forename: Junzhen
authors.initials: J
authors.lastname: Fan
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, P. R. China.
authors.forename: Hongjun
authors.initials: H
authors.lastname: Zhu