title: Ocular wavefront analysis of aspheric compared with spherical monofocal intraocular lenses in cataract surgery: Systematic review with metaanalysis.
abstract: This review was conducted to compare the physical effect of aspheric IOL implantation on wavefront properties with that of spherical IOL implantation. The peer-reviewed literature was systematically searched in Medline, Embase, Web of Science, Biosis, and the Cochrane Library according to the Cochrane Collaboration method. Inclusion criteria were randomized controlled trials comparing the use of aspheric versus spherical monofocal IOL implantation that assessed visual acuity, contrast sensitivity, or quality of vision. A secondary outcome was ocular wavefront analysis; spherical aberration, higher-order aberrations (HOAs), coma, and trefoil were evaluated. Effects were calculated as standardized mean differences (Hedges g) and were pooled using random-effect models. Thirty-four of 43 studies provided data for wavefront analysis. Aspheric monofocal IOL implantation resulted in less ocular spherical aberration and fewer ocular HOAs than spherical IOLs. This might explain the better contrast sensitivity in patients with aspheric IOLs.
authors.affiliation: From the Mannheim Institute of Public Health (Schuster, Vossmerbaeumer), Social and Preventive Medicine, Medical Faculty Mannheim, University of Heidelberg, and the Department of General Internal Medicine and Psychosomatics (Tesarz), Medical Hospital, University of Heidelberg, Heidelberg, and the Department of Ophthalmology (Schuster, Vossmerbaeumer), Mainz Medical Center, University of Mainz, Mainz, Germany. Electronic address: alexander.k.schuster@gmx.de.
authors.forename: Alexander K
authors.initials: AK
authors.lastname: Schuster
authors.affiliation: From the Mannheim Institute of Public Health (Schuster, Vossmerbaeumer), Social and Preventive Medicine, Medical Faculty Mannheim, University of Heidelberg, and the Department of General Internal Medicine and Psychosomatics (Tesarz), Medical Hospital, University of Heidelberg, Heidelberg, and the Department of Ophthalmology (Schuster, Vossmerbaeumer), Mainz Medical Center, University of Mainz, Mainz, Germany.
authors.forename: Jonas
authors.initials: J
authors.lastname: Tesarz
authors.affiliation: From the Mannheim Institute of Public Health (Schuster, Vossmerbaeumer), Social and Preventive Medicine, Medical Faculty Mannheim, University of Heidelberg, and the Department of General Internal Medicine and Psychosomatics (Tesarz), Medical Hospital, University of Heidelberg, Heidelberg, and the Department of Ophthalmology (Schuster, Vossmerbaeumer), Mainz Medical Center, University of Mainz, Mainz, Germany.
authors.forename: Urs
authors.initials: U
authors.lastname: Vossmerbaeumer
mesh_terms: D015350:Contrast Sensitivity / Q000502:physiology; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D018918:Phacoemulsification; D011474:Prosthesis Design; D019591:Pseudophakia / Q000503:physiopathology; D014792:Visual Acuity