title: Evaluation of safety and efficacy of 980-nm diode laser-assisted lipolysis versus traditional liposuction for submental rejuvenation: A randomized clinical trial.
abstract: BACKGROUND
  Submental fat accumulation and skin laxity is a frequent concern of cosmetic patients.
  
  
  OBJECTIVE
  The aim of this randomized prospective controlled clinical trial was to compare the efficacy and safety of laser-assisted lipolysis and liposuction in the submental rejuvenation.
  
  
  METHODS
  Thirty-six female adults were enrolled in this clinical trial and were categorized into two groups: group 1 underwent 980-nm diode laser with the power of 6-8 W and group 2 underwent traditional liposuction. Patients were evaluated with ultrasonography 2 weeks and 2 months after the procedures.
  
  
  RESULTS
  Ultrasonographic evaluation reported the significant reduction of fat thickness in each group compared with the baseline (p value < 0.001). At the 2 weeks and 2 months follow-up visit, fat thickness reduction was significantly higher in the lipolysis group (p value < 0.05). Overall patients' satisfaction in lipolysis group was higher than liposuction with 11 (61%) of lipolysis patients being very satisfied in contrast to 10 (55.5%) of liposuction patients reporting "dissatisfied or neutral" results.
  
  
  CONCLUSIONS
  Laser-assisted lipolysis using 980-nm diode is approved to be safe and effective for skin tightening and rejuvenation of the submental area and seems to be a better option than traditional techniques for treatment of this cosmetic problem.
authors.affiliation: a Laser Application in Medical Science Research Center, Shahid Beheshti University of Medical Sciences , Tehran , Iran.
authors.forename: Neda
authors.initials: N
authors.lastname: Valizadeh
authors.affiliation: a Laser Application in Medical Science Research Center, Shahid Beheshti University of Medical Sciences , Tehran , Iran.
authors.forename: Niloofar Y
authors.initials: NY
authors.lastname: Jalaly
authors.affiliation: b Department of Dermatology , Azad Tehran University of Medical Sciences , Tehran , Iran.
authors.forename: Manijeh
authors.initials: M
authors.lastname: Zarghampour
authors.affiliation: a Laser Application in Medical Science Research Center, Shahid Beheshti University of Medical Sciences , Tehran , Iran.
authors.forename: Behrooz
authors.initials: B
authors.lastname: Barikbin
authors.affiliation: c Department of Imaging , Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences , Tehran , Iran.
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Haghighatkhah
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging / Q000601:surgery; D000328:Adult; D002404:Catheterization / Q000009:adverse effects; D002680:Chin / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D054023:Lasers, Semiconductor / Q000009:adverse effects / Q000627:therapeutic use*; D015187:Lipectomy / Q000379:methods*; D008875:Middle Aged; D017060:Patient Satisfaction; D011446:Prospective Studies; D012060:Rejuvenation; D014463:Ultrasonography
keywords: lipolysis; liposuction; rejuvenation; submental