title: The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract.
abstract: Vimentin is an intermediate filament protein normally expressed in cells of mesenchymal origin, e.g. myofibroblasts, chondrocytes, macrophages, and endothelial cells. The expression of vimentin, which has been thought of as the main mesenchymal marker, is also detected in tumour tissue. In tumours of the gastrointestinal tract vimentin expression is usually correlated with advanced stage of tumour, lymph node metastasis, and patient survival.
authors.affiliation: Chair and Department of Histology and Embryology, Faculty of Medicine and Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Marlena
authors.initials: M
authors.lastname: Brzozowa
authors.affiliation: Chair and Department of Histology and Embryology, Faculty of Medicine and Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Wyrobiec
authors.affiliation: Chair and Department of Histology and Embryology, Faculty of Medicine and Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Izabela
authors.initials: I
authors.lastname: Kołodziej
authors.affiliation: Chair and Department of Histology and Embryology, Faculty of Medicine and Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Mateusz
authors.initials: M
authors.lastname: Sitarski
authors.affiliation: Chair and Department of Histology and Embryology, Faculty of Medicine and Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Natalia
authors.initials: N
authors.lastname: Matysiak
authors.affiliation: Chair and Department of Histology and Embryology, Faculty of Medicine and Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Edyta
authors.initials: E
authors.lastname: Reichman-Warmusz
authors.affiliation: Chair and Department of Histology and Embryology, Faculty of Medicine and Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Żaba
authors.affiliation: Chair and Department of Histology and Embryology, Faculty of Medicine and Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.
authors.forename: Romuald
authors.initials: R
authors.lastname: Wojnicz
keywords: E-cadherin; gastrointestinal tumours; vimentin