title: Are we entering a new age for human vaccine adjuvants?
abstract: Major advances in adjuvant development for human vaccines have been reported recently for a range of indications, including malaria, influenza and varicella zoster virus. Furthermore, there is an increased understanding of adjuvant mechanisms of action and a greater emphasis on the importance of formulation and characterization. This progress may signify a new golden age of vaccine adjuvant discovery and development.
authors.affiliation: Novartis Vaccines, Cambridge, MA, USA.
authors.forename: Derek T
authors.initials: DT
authors.lastname: O'Hagan
authors.forename: Christopher B
authors.initials: CB
authors.lastname: Fox
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage* / Q000302:isolation & purification* / Q000494:pharmacology; D055808:Drug Discovery / Q000639:trends; D006801:Humans; D014611:Vaccination / Q000379:methods*; D014612:Vaccines / Q000008:administration & dosage / Q000276:immunology*
chemical_list: D000276:Adjuvants, Immunologic; D014612:Vaccines
keywords: MF59; MPL; QS21; formulation; vaccine adjuvant