title: Infantile Hemangioma: Clinical Characteristics and Efficacy of Treatment with the Long-Pulsed 1,064-nm Neodymium-Doped Yttrium Aluminum Garnet Laser in 794 Chinese Patients.
abstract: OBJECTIVE
  This study aimed to evaluate the clinical characteristics of infantile hemangiomas (IHs) and the safety and efficacy of the long-pulse 1,064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser for definitive treatment of IHs in 794 Chinese patients.
  
  
  METHODS
  Infants with hemangiomas who had received long-pulse 1,064-nm Nd:YAG laser treatment in our department in the last 5 years were recruited. Demographic and clinical characteristics were recorded and outcomes of long-pulse 1,064-nm Nd:YAG laser treatment were assessed. Statistical analyses were performed to identify factors that affected the efficacy of treatment.
  
  
  RESULTS
  The efficacy of long-pulse 1,064-nm Nd:YAG laser for the treatment of IHs in all patients in our study was 87.57%. Efficacy did not depend on sex or the location of the lesion. Older age and superficial hemangioma were the primary factors contributing to greater efficacy of long-pulse 1,064-nm Nd:YAG laser treatment for IHs. The most common side effects were pigment changes, skin atrophy, and wrinkled redundant skin, which usually resolved spontaneously within 1 to 3 years.
  
  
  CONCLUSIONS
  Long-pulse 1,064-nm Nd:YAG laser is a safe and efficacious treatment for IHs.
authors.affiliation: Department of Dermatology and Venereology, First Hospital of Jilin University, Changchun, China.
authors.forename: Shu-xia
authors.initials: SX
authors.lastname: Zhong
authors.affiliation: Department of Epidemiology and Health Statistics, Public Health College, Jilin University, Changchun, China.
authors.forename: Yu-chun
authors.initials: YC
authors.lastname: Tao
authors.affiliation: Department of Dermatology and Venereology, First Hospital of Jilin University, Changchun, China.
authors.forename: Jun-feng
authors.initials: JF
authors.lastname: Zhou
authors.affiliation: Department of Dermatology and Venereology, First Hospital of Jilin University, Changchun, China.
authors.forename: Yuan-yuan
authors.initials: YY
authors.lastname: Liu
authors.affiliation: Department of Dermatology and Venereology, First Hospital of Jilin University, Changchun, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Yao
authors.affiliation: Department of Dermatology and Venereology, First Hospital of Jilin University, Changchun, China.
authors.forename: Shan-shan
authors.initials: SS
authors.lastname: Li
mesh_terms: D005260:Female; D018324:Hemangioma, Capillary / Q000532:radiotherapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D053685:Laser Therapy / Q000379:methods*; D053844:Lasers, Solid-State; D008297:Male; D012878:Skin Neoplasms / Q000532:radiotherapy*; D016896:Treatment Outcome