title: Survival of patients with gastric lymphoma in Germany and in the United States.
abstract: OBJECTIVE
  This study aims to examine survival for gastric lymphomas and its main subtypes, mucosa-associated lymphoid tissue lymphoma (MALT), and diffuse large B-cell lymphoma (DLBCL), in Germany and in the United States.
  
  
  METHODS
  Data for patients diagnosed in 1997-2010 were used from 10 population-based German cancer registries and compared to the data from the US Surveillance, Epidemiology and End Results (SEER) 13 registries database. Patients age 15-74 diagnosed with gastric lymphomas were included in the analysis. Period analysis and modeled period analysis were used to estimate 5-year and 10-year relative survival (RS) in 2002-2010 and survival trends from 2002-2004 to 2008-2010.
  
  
  RESULTS
  Overall, the database included 1534 and 2688 patients diagnosed with gastric lymphoma in 1997-2010 in Germany and in the United States, respectively. Survival was substantially higher for MALT (5-year and 10-year RS: 89.0% and 80.9% in Germany, 93.8% and 86.8% in the United States) than for DLBCL (67.5% and 59.2% in Germany, and 65.3% and 54.7% in the United States) in 2002-2010. Survival was slightly higher among female patients and decreased by age for gastric lymphomas combined and its main subtypes. A slight, nonsignificant, increase in the 5-year RS for gastric lymphomas combined was observed in Germany and the United States, with increases in 5-year RS between 2002-2004 and 2008-2010 from 77.1% to 81.0% and from 77.3% to 82.0%, respectively. Five-year RS of MALT exceeded 90% in 2008-2010 in both countries.
  
  
  CONCLUSIONS
  Five-year RS of MALT meanwhile exceeds 90% in both Germany and the United States, but DLBCL has remained below 70% in both countries.
authors.affiliation: Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
authors.forename: Felipe A
authors.initials: FA
authors.lastname: Castro
authors.affiliation: Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
authors.forename: Lina
authors.initials: L
authors.lastname: Jansen
authors.affiliation: Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.
authors.forename: Agne
authors.initials: A
authors.lastname: Krilaviciute
authors.affiliation: Institute of Cancer Epidemiology, University of Lübeck, Lübeck, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Katalinic
authors.affiliation: Cardeza Foundation and Division of Hematology, Department of Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.
authors.forename: Dianne
authors.initials: D
authors.lastname: Pulte
authors.affiliation: Lower Saxony Cancer Registry, Oldenburg, Germany.
authors.forename: Eunice
authors.initials: E
authors.lastname: Sirri
authors.affiliation: Cancer Registry of Rhineland-Palatinate, Institute of Medical Biostatistics Epidemiology and Informatics, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany.
authors.forename: Meike
authors.initials: M
authors.lastname: Ressing
authors.affiliation: Saarland Cancer Registry, Saarbrücken, Germany.
authors.forename: Bernd
authors.initials: B
authors.lastname: Holleczek
authors.affiliation: Cancer Registry of Bremen, Leibniz-Institute for Epidemiology and Prevention Research and Epidemiology - BIPS, Bremen, Germany.
authors.forename: Sabine
authors.initials: S
authors.lastname: Luttmann
authors.affiliation: Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.|German Cancer Consortium (DKTK), Heidelberg, Germany.
authors.forename: Hermann
authors.initials: H
authors.lastname: Brenner
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000453:epidemiology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D012042:Registries; D013274:Stomach Neoplasms / Q000401:mortality*; D015996:Survival Rate; D013997:Time Factors; D014481:United States / Q000453:epidemiology; D055815:Young Adult
keywords: cancer registry; diffuse large B-cell lymphoma; mucosa-associated lymphoid tissue; period analysis