title: [The correlation analysis of coagulation detection and blood routine parameters of sudden hearing loss].
abstract: OBJECTIVE
  Through the analysis of coagulation convention and blood routine parameters of sudden hearing loss (SHL) patients, further prove the correlation of sudden deafness and the the inner ear microcirculation, to guide clinical diagnosis and treatment.
  
  
  METHODS
  Select 424 patients (448 ears) with sudden deafness in our department to SHL group. According to hearing curve is classified into low intermediate frequency descent group, high frequency drop and full frequency group, and drawing 244 cases in the same period of hospitalization deviated septum, vocal cord polyp patients as control group. All patients' coagulation detection, D-dimer, blood leukocytes, neutrophils and platelet count percentages were analyzed. Then a meaningful factor multivariate Logistic regression analysis was made.
  
  
  RESULTS
  There was a statistically significant difference between the two groups' prothrombin time, international normalized ratio, activated partial thromboplastin time, thrombin time measurement, fibrinogen, D-dimer, platelet count, white blood cell, neutrophil ratio(P<0.05); Logistic regression analysis showed that the prothrombin, thrombin time measurement, fibrinogen, D-dimer, neutrophil incidence of sudden hearing loss associated risk factors.
  
  
  CONCLUSIONS
  SHL in patients with coagulation dysfunction may be involved in the occurrence of SHL development mechanism, and there is a correlation of the SHL and the dysfunction of inner ear microcirculation.
authors.forename: Fengxiang
authors.initials: F
authors.lastname: Bao
authors.forename: Shujia
authors.initials: S
authors.lastname: Zhang
authors.forename: Yanping
authors.initials: Y
authors.lastname: Zhang
authors.forename: Xuetao
authors.initials: X
authors.lastname: Zhu
authors.forename: Weiwei
authors.initials: W
authors.lastname: Liu
mesh_terms: D001778:Blood Coagulation Disorders / Q000150:complications*; D007758:Ear, Inner / Q000098:blood supply*; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D005340:Fibrinogen; D003639:Hearing Loss, Sudden / Q000097:blood* / Q000150:complications; D006801:Humans; D015994:Incidence; D012307:Risk Factors
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D005340:Fibrinogen