title: [Recommendation for genetic testing in patients suffering from gynecological malignancy].
abstract: OBJECTIVE
  To present an overview of indications and recommendations for genetic testing in patients with hereditary susceptibility to develop malignant gynecological tumors.
  
  
  METHODS
  Review.
  
  
  METHODS
  Gynecological Oncology Center, Department of Obstetrics and Gynecology, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague.
  
  
  METHODS
  Literature review and recommendations for practice based on evidence and clinical experience.
  
  
  CONCLUSIONS
  Women with hereditary susceptibility to malignant gynecological tumors represent only a relatively small part of the population. However, it is a well-defined risk factor and set of preventive and prophylactic measures can minimize the risk of cancer development (or risk of death from tumor). Knowledge of the indications for genetic testing is one of the basic knowledge of every gynecologist.
authors.forename: Michal
authors.initials: M
authors.lastname: Zikán
mesh_terms: D019317:Evidence-Based Medicine; D005260:Female; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006801:Humans; D010051:Ovarian Neoplasms / Q000235:genetics*; D017410:Practice Guidelines as Topic; D011247:Pregnancy
keywords: BRCA1; BRCA2; Lynch syndrome; Peutz-Jeghers syndrome.; hereditary susceptibility