title: Fabrication of bone cement that fully transforms to carbonate apatite.
abstract: The objective of this study was to fabricate a type of bone cement that could fully transform to carbonate apatite (CO3Ap) in physiological conditions. A combination of calcium carbonate (CaCO3) and dicalcium phosphate anhydrous was chosen as the powder phase and mixed with one of three kinds of sodium phosphate solutions: NaH2PO4, Na2HPO4, or Na3PO4. The cement that fully transformed to CO3Ap was fabricated using vaterite, instead of calcite, as a CaCO3 source. Their stability in aqueous solutions was different, regardless of the type of sodium phosphate solution. Rate of transformation to CO3Ap in descending order was Na3PO4>Na2HPO4>NaH2PO4. Transformation rate could be affected by the pH of solution. Results of this study showed that it was advantageous to use vaterite to fabricate CO3Ap-forming cement.
authors.affiliation: Department of Biomaterials, Faculty of Dental Science, Kyushu University.
authors.forename: Arief
authors.initials: A
authors.lastname: Cahyanto
authors.forename: Michito
authors.initials: M
authors.lastname: Maruta
authors.forename: Kanji
authors.initials: K
authors.lastname: Tsuru
authors.forename: Shigeki
authors.initials: S
authors.lastname: Matsuya
authors.forename: Kunio
authors.initials: K
authors.lastname: Ishikawa
mesh_terms: D001031:Apatites / Q000737:chemistry*; D001843:Bone Cements / Q000138:chemical synthesis*; D002119:Calcium Carbonate / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D010710:Phosphates / Q000737:chemistry; D016062:Porosity; D012996:Solutions
chemical_list: D001031:Apatites; D001843:Bone Cements; D002130:Calcium Phosphates; D010710:Phosphates; D012996:Solutions; D002119:Calcium Carbonate; C485829:calcium phosphate, dibasic, anhydrous; C018279:sodium phosphate