title: Cephazolin-induced toxic epidermal necrolysis treated with intravenous immunoglobulin and N-acetylcysteine.
abstract: Toxic epidermal necrolysis is the most severe form of drug-induced skin reaction and includes denudation of >30% of total body surface area. The mechanism of disease is not completely understood, but immunologic mechanisms, cytotoxic reactions, and delayed hypersensitivity seem to be involved. We report a case of cephazolin-induced toxic epidermal necrolysis treated with intravenous immunoglobulin and N-acetylcysteine with excellent response.
authors.affiliation: Units of Infectology and Dermatology, Department of Internal Medicine, National University of Colombia, 111321 Bogotá, Colombia.
authors.forename: Carlos
authors.initials: C
authors.lastname: Saavedra
authors.affiliation: Units of Infectology and Dermatology, Department of Internal Medicine, National University of Colombia, 111321 Bogotá, Colombia.
authors.forename: Paola
authors.initials: P
authors.lastname: Cárdenas
authors.affiliation: Units of Infectology and Dermatology, Department of Internal Medicine, National University of Colombia, 111321 Bogotá, Colombia.
authors.forename: Héctor
authors.initials: H
authors.lastname: Castellanos
authors.affiliation: Units of Infectology and Dermatology, Department of Internal Medicine, National University of Colombia, 111321 Bogotá, Colombia.
authors.forename: Kateir
authors.initials: K
authors.lastname: Contreras
authors.affiliation: Units of Infectology and Dermatology, Department of Internal Medicine, National University of Colombia, 111321 Bogotá, Colombia.
authors.forename: J R
authors.initials: JR
authors.lastname: Castro