title: Yolk sac tumor of vagina: a case report.
abstract: Malignant germ-cell tumors (MGCT) are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Yolk sac (endodermal sinus) tumor is one of the malignant germ cell tumor that usually involves the gonads (ovaries and testes). Its occurrence in the vagina is extremely rare. We report a 6-months old girl presented with a vaginal mass diagnosed as a yolk sac tumor. This diagnosis is confirmed by histopathologic examination, immunehistochemical studies as well as elevated serum alpha fetoprotein (AFP).
authors.affiliation: Department of Pathology, King Khalid University Hospital, King Saud University Riyadh, Saudi Arabia.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Alhumidi
authors.affiliation: Department of Pathology, King Khalid University Hospital, King Saud University Riyadh, Saudi Arabia.
authors.forename: Safa
authors.initials: S
authors.lastname: Al Shaikh
authors.affiliation: Department of Pathology, King Khalid University Hospital, King Saud University Riyadh, Saudi Arabia.
authors.forename: Abdullah
authors.initials: A
authors.lastname: Alhammadi
mesh_terms: D003131:Combined Modality Therapy; D018240:Endodermal Sinus Tumor / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D016896:Treatment Outcome; D014625:Vaginal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
keywords: Yolk sac tumor; alpha fetoprotein; endodermal sinus tumor; vagina