title: [Efficacy of a fentanyl citrate buccal tablet for esophageal cancer pain management in a patient unable to take oral medication].
abstract: We report a case ofa 60-year old male esophageal cancer patient who was unable to take oral medication, but was successfully treated using a fentanyl citrate buccal tablet. The patient survived a suicide attempt as a youth in which he ingested poison, but was left with a stricture of the esophagus. It became difficult for him to take nutrition orally, and he underwent an esophageal bypass operation, although he still required frequent endoscopic esophageal dilation. He subsequently presented with an anastomotic stenosis due to anastomotic leakage, and oral intake became completely impossible. The onset of esophageal cancer presented as corrosive esophagitis. We used oxycodone hydrochloride to treat a sharp pain resulting from cataplectic cancer in the jejunal tube, but this provided only limited pain relief. We therefore used a fentanyl citrate oral mucosa absorption preparation with a rescue agent, which did provide effective pain relief. Thus a fentanyl citrate buccal tablet could effectively relief pain in cancer patients who are unable to receive oral medication.
authors.affiliation: Dept. of Surgery, Taragi Municipal Hospital.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Fujimura
authors.forename: Osamu
authors.initials: O
authors.lastname: Nakahara
authors.forename: Shigeki
authors.initials: S
authors.lastname: Ohshima
authors.forename: Hideo
authors.initials: H
authors.lastname: Baba
mesh_terms: D000701:Analgesics, Opioid / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D004938:Esophageal Neoplasms / Q000628:therapy*; D017809:Fatal Outcome; D005283:Fentanyl / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D059408:Pain Management; D010166:Palliative Care; D013607:Tablets
chemical_list: D000701:Analgesics, Opioid; D013607:Tablets; D005283:Fentanyl