title: para-Sulphonato-calix[n]arenes as selective activators for the passage of molecules across the Caco-2 model intestinal membrane.
abstract: The passage of Lucifer Yellow across the Caco-2 intestinal model membrane has been studied for the para-sulphonato-calix[n]arenes, the results show that para-sulphonato-calix[4]arene and para-sulphonato-calix[8]arene activate membrane passage when used simultaneously with a transport probe, Lucifer Yellow, whereas para-sulphonato-calix[6]arene has no effect.
authors.affiliation: University of Debrecen, Department of Pharmaceutical Technology, Debrecen, Hungary. vecsernyes.miklos@pharm.unideb.hu bacskay.ildiko@pharm.unideb.hu.
authors.forename: Eszter
authors.initials: E
authors.lastname: Roka
authors.forename: Miklos
authors.initials: M
authors.lastname: Vecsernyes
authors.forename: Ildiko
authors.initials: I
authors.lastname: Bacskay
authors.forename: Caroline
authors.initials: C
authors.lastname: Félix
authors.forename: Moez
authors.initials: M
authors.lastname: Rhimi
authors.forename: Anthony W
authors.initials: AW
authors.lastname: Coleman
authors.forename: Florent
authors.initials: F
authors.lastname: Perret
mesh_terms: D001692:Biological Transport; D018938:Caco-2 Cells; D047250:Calixarenes / Q000737:chemistry* / Q000493:pharmacokinetics / Q000494:pharmacology*; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects*; D008954:Models, Biological; D015394:Molecular Structure; D013451:Sulfonic Acids / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D013451:Sulfonic Acids; D047250:Calixarenes