title: Elongator and its epigenetic role in plant development and responses to abiotic and biotic stresses.
abstract: Elongator, a six-subunit protein complex, was initially isolated as an interactor of hyperphosphorylated RNA polymerase II in yeast, and was subsequently identified in animals and plants. Elongator has been implicated in multiple cellular activities or biological processes including tRNA modification, histone modification, DNA demethylation or methylation, tubulin acetylation, and exocytosis. Studies in the model plant Arabidopsis thaliana suggest that the structure of Elongator and its functions are highly conserved between plants and yeast. Disruption of the Elongator complex in plants leads to aberrant growth and development, resistance to abiotic stresses, and susceptibility to plant pathogens. The morphological and physiological phenotypes of Arabidopsis Elongator mutants are associated with decreased histone acetylation and/or altered DNA methylation. This review summarizes recent findings related to the epigenetic function of Elongator in plant development and responses to abiotic and biotic stresses.
authors.affiliation: Department of Microbiology and Cell Science, University of Florida Gainesville, FL, USA.
authors.forename: Yezhang
authors.initials: Y
authors.lastname: Ding
authors.affiliation: Department of Microbiology and Cell Science, University of Florida Gainesville, FL, USA.
authors.forename: Zhonglin
authors.initials: Z
authors.lastname: Mou
keywords: DNA methylation; Elongator; abiotic stress; histone acetylation; plant development; plant immunity; tRNA modification