title: A simple fluorescent off-on probe for the discrimination of cysteine from glutathione.
abstract: A simple and stable fluorescent off-on probe for discrimination of cysteine (Cys) from glutathione (GSH) has been developed by combining resorufin with 7-nitrobenzofurazan. The probe, displaying distinct emission patterns for Cys and GSH at just one excitation wavelength, can be used for simultaneous determination of Cys and GSH in human plasma.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. mahm@iccas.ac.cn lixh@iccas.ac.cn.
authors.forename: Xinghui
authors.initials: X
authors.lastname: Gao
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Li
authors.forename: Lihong
authors.initials: L
authors.lastname: Li
authors.forename: Jin
authors.initials: J
authors.lastname: Zhou
authors.forename: Huimin
authors.initials: H
authors.lastname: Ma
mesh_terms: D003545:Cysteine / Q000097:blood / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D005978:Glutathione / Q000097:blood / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure
chemical_list: D005456:Fluorescent Dyes; D005978:Glutathione; D003545:Cysteine