title: Golgi post-translational modifications and associated diseases.
abstract: For non specialists, Golgi is a very well known subcellular compartment involved in secretion and correct targeting of soluble and transmembrane proteins. Nevertheless, Golgi is also specifically involved in many different and diverse post-translational modifications. Through its diverse functions, Golgi is not only able to modify secreted and transmembrane proteins but also cytoplasmic proteins. The Golgi apparatus research field is so broad that an exhaustive review of this organelle is not doable here. The goal of this review is to cover the main post-translational modifications occurring at the Golgi level and present the identified associated diseases.
authors.affiliation: CNRS-UMR 8576, Structural and Functional Glycobiology unit, FRABIO, University of Lille, 59655, Villeneuve d'Ascq, France.
authors.forename: Sven
authors.initials: S
authors.lastname: Potelle
authors.forename: André
authors.initials: A
authors.lastname: Klein
authors.forename: François
authors.initials: F
authors.lastname: Foulquier
mesh_terms: D000818:Animals; D006056:Golgi Apparatus / Q000235:genetics* / Q000378:metabolism*; D006801:Humans; D008659:Metabolic Diseases / Q000235:genetics* / Q000378:metabolism*; D011499:Protein Processing, Post-Translational / Q000235:genetics*