title: Prognostic value of galectin-3 in patients with heart failure.
abstract: Galectins are a family of soluble β-galactoside-binding lectins that have important role in inflammation, immunity, and cancer. Galectin-3 as a part of this lectin family plays a very important role in development of heart failure. According to recent papers, galectin-3 plasma level correlates with heart failure outcome, primarily with rehospitalisation and death from heart failure. This paper summarizes the most recent advances in galectin-3 research, with the accent on the role of galectin-3 in pathophysiology of myocardial remodelling and heart failure development--with preserved and reduced ejection fraction, and some implication on development of new disease modifying drugs.
authors.affiliation: Department for Cardiovascular Disease, Clinic for Internal Medicine, University Hospital Centre Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
authors.forename: Ivica
authors.initials: I
authors.lastname: Bošnjak
authors.affiliation: Department for Cardiovascular Disease, Clinic for Internal Medicine, University Hospital Centre Osijek, J. Huttlera 4, 31000 Osijek, Croatia ; Faculty of Medicine Osijek, University Josipi Juraj Strossmayer Osijek, J. Huttlera 4, 31000 Osijek, Croatia.
authors.forename: Kristina
authors.initials: K
authors.lastname: Selthofer-Relatić
authors.affiliation: Faculty of Medicine Osijek, University Josipi Juraj Strossmayer Osijek, J. Huttlera 4, 31000 Osijek, Croatia ; Department for Gastroenterology, Clinic for Internal Medicine, University Hospital Centre Osijek, Osijek, Croatia.
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Včev
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood / Q000378:metabolism; D037502:Galectin 3 / Q000097:blood* / Q000378:metabolism; D006333:Heart Failure / Q000097:blood* / Q000378:metabolism; D006801:Humans
chemical_list: D015415:Biomarkers; D037502:Galectin 3