title: Validity of Vascular Calcification as a Screening Tool and as a Surrogate End Point in Clinical Research.
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.). carmine.zoccali@tin.it.
authors.forename: Carmine
authors.initials: C
authors.lastname: Zoccali
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Davide
authors.initials: D
authors.lastname: Bolignano
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Graziella
authors.initials: G
authors.lastname: D'Arrigo
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Friedo W
authors.initials: FW
authors.lastname: Dekker
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Danilo
authors.initials: D
authors.lastname: Fliser
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Gunnar H
authors.initials: GH
authors.lastname: Heine
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Kitty J
authors.initials: KJ
authors.lastname: Jager
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Mehmet
authors.initials: M
authors.lastname: Kanbay
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Francesca
authors.initials: F
authors.lastname: Mallamaci
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Ziad
authors.initials: Z
authors.lastname: Massy
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Alberto
authors.initials: A
authors.lastname: Ortiz
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Gianfranco
authors.initials: G
authors.lastname: Parati
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Patrick
authors.initials: P
authors.lastname: Rossignol
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Giovanni
authors.initials: G
authors.lastname: Tripepi
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Raymond
authors.initials: R
authors.lastname: Vanholder
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Andrzej
authors.initials: A
authors.lastname: Wiecek
authors.affiliation: From the CNR-IFC Pathophysiology of Renal Diseases and Hypertension Unit, Reggio Calabria, Italy (C.Z., D.B., G.D'A., F.M., G.T.); Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands (F.W.D.); Department of Internal Medicine IV, Saarland University Medical Centre, Homburg/Saar, Germany (D.F., G.H.H.); Department of Medical Informatics, Academic Medical Center, European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, University of Amsterdam, Amsterdam, The Netherlands (K.J.J.); Division of Nephrology, Department of Medicine, Koc University School of Medicine, Istanbul, Turkey (M.K.); Nephrology, Dialysis, and Transplantation Unit and CNR-IFC Clinical Epidemiology, Reggio Calabria, Italy (F.M.); Paris Ile de France Ouest (UVSQ) University, Paris, France (Z.M.); Fundación Jiménez Díaz, Universidad Autónoma de Madrid, Fundación Renal Iñigo Alvarez de Toledo, Madrid, Spain (A.O.); Department of Cardiovascular, Neural, and Metabolic Sciences, S. Luca Hospital, Istituto Auxologico Italiano & University of Milan-Bicocca, Milan, Italy (G.P.); INSERM, Centre d'Investigations Cliniques-Plurithématique 1433, INSERM U1116, Nancy, France (P.R.); Département de Cardiologie, CHU Nancy, Institut Lorrain du Cœur et des Vaisseaux, Vandoeuvre lès Nancy, France (P.R.); Université de Lorraine, Nancy, France (P.R.); INI-CRCT (Cardiovascular and Renal Clinical Trialists), French-Clinical Research Infrastructure Network (F-CRIN), Nancy, France (P.R.); Division of Nephrology, Department of Internal Medicine, Ghent University Hospital, University Hospital Gent, Ghent, Belgium (R.V.); Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Poland (A.W.); and INSERM U970, Hopital Européen Georges Pompidou, Paris, France (G.L.).
authors.forename: Gerard
authors.initials: G
authors.lastname: London
mesh_terms: D015415:Biomarkers; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000453:epidemiology; D002118:Calcium / Q000032:analysis*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000453:epidemiology; D003331:Coronary Vessels / Q000737:chemistry*; D050171:Dyslipidemias / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D015201:Meta-Analysis as Topic; D009042:Motivation; D064887:Observational Studies as Topic; D017410:Practice Guidelines as Topic; D011237:Predictive Value of Tests; D016032:Randomized Controlled Trials as Topic / Q000379:methods; D015203:Reproducibility of Results; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D015415:Biomarkers; D002118:Calcium