title: Amiodarone-induced multiorgan toxicity with ocular findings on confocal microscopy.
abstract: Amiodarone is an antiarrhythmic medication that can adversely effect various organs including lungs, thyroid gland, liver, eyes, skin, and nerves. The risk of adverse effects increases with high doses and prolonged use. We report a 54-year-old female who presented with multiorgan toxicity after 8 months of low dose (200 mg/day) amiodarone treatment. The findings of confocal microscopy due to amiodarone-induced keratopathy are described. Amiodarone may cause multiorgan toxicity even at lower doses and for shorter treatment periods.
authors.affiliation: Department of Cardiology, Central Hospital, Bayrakli, Izmir, Turkey.
authors.forename: Ugur
authors.initials: U
authors.lastname: Turk
authors.affiliation: Department of Dermatology, Ege University Medical Faculty, Bornova, Izmir, Turkey.
authors.forename: Bengu Gerceker
authors.initials: BG
authors.lastname: Turk
authors.affiliation: Department of Ophthalmology, Ege University Medical Faculty, Bornova, Izmir, Turkey.
authors.forename: Suzan Guven
authors.initials: SG
authors.lastname: Yılmaz
authors.affiliation: Department of Cardiology, Central Hospital, Bayrakli, Izmir, Turkey.
authors.forename: Esref
authors.initials: E
authors.lastname: Tuncer
authors.affiliation: Department of Cardiology, Central Hospital, Bayrakli, Izmir, Turkey.
authors.forename: Emin
authors.initials: E
authors.lastname: Alioğlu
authors.affiliation: Department of Dermatology, Ege University Medical Faculty, Bornova, Izmir, Turkey.
authors.forename: Tugrul
authors.initials: T
authors.lastname: Dereli
mesh_terms: D000638:Amiodarone / Q000633:toxicity*; D000889:Anti-Arrhythmia Agents / Q000633:toxicity*; D001281:Atrial Fibrillation / Q000188:drug therapy; D003316:Corneal Diseases / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D018613:Microscopy, Confocal; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D000889:Anti-Arrhythmia Agents; D000638:Amiodarone
keywords: Amiodarone; Confocal Microscopy; Multiorgan Toxicity