title: Improving biocompatibility of zirconia surface by incorporating Ca ions.
abstract: Though zirconia has been used in dental implant fixtures, the biocompatibility of the zirconia surface is not optimal for the surrounding tissue, and many surface modifications have been attempted. We have developed a novel method for improving the biocompatibility of zirconia by incorporating Ca ions. Elemental analysis showed that calcium ions become thoroughly incorporated into the zirconia surface after firing with calcium acetate. Mechanical tests indicated that the Ca ions had little effect on the flexural strength and hardness. Moreover, incorporating Ca ions also dramatically improved the water wettability of specimens that had been soaked in a simulated body fluid. The surface of the Ca-modified zirconia demonstrated good initial cell attachment.
authors.affiliation: Department of Dental Materials Science, School of Dentistry, Aichi Gakuin University.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Sasaki
authors.forename: Tatsuhide
authors.initials: T
authors.lastname: Hayashi
authors.forename: Masaki
authors.initials: M
authors.lastname: Asakura
authors.forename: Masahiko
authors.initials: M
authors.lastname: Ando
authors.forename: Tatsushi
authors.initials: T
authors.lastname: Kawai
authors.forename: Seiji
authors.initials: S
authors.lastname: Ban
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D002118:Calcium / Q000737:chemistry*; D049109:Cell Proliferation; D004548:Elasticity; D004577:Electron Probe Microanalysis; D006244:Hardness; D007477:Ions; D051379:Mice; D008855:Microscopy, Electron, Scanning; D010006:Osteoblasts / Q000187:drug effects; D013499:Surface Properties; D017155:Wettability; D014961:X-Ray Diffraction; D015040:Zirconium / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D007477:Ions; D015040:Zirconium; C028541:zirconium oxide; D002118:Calcium