title: Intraindividual comparative analysis of capsule opacification after implantation of 2 single-piece hydrophobic acrylic intraocular lenses models: Three-year follow-up.
abstract: OBJECTIVE
  To compare the 3-year postoperative anterior (ACO) and posterior (PCO) capsule opacification and the level of anterior capsule retraction after implantation of 2 single-piece hydrophobic acrylic intraocular lens (IOL) models.
  
  
  METHODS
  Hospital of St. John of God, Vienna, Austria.
  
  
  METHODS
  Comparative randomized controlled double-blind clinical trial.
  
  
  METHODS
  Eyes with bilateral cataract were evaluated. Each patient had an Acrysof SA60AT (interrupted optic edge) IOL implanted in 1 eye (Group A) and a Tecnis ZCB00 (continuous optic edge) IOL implanted in the fellow eye (Group B). One and 3 years postoperatively, PCO was evaluated using Evaluation of Posterior Capsule Opacification software and the ACO level and capsule-retraction level were evaluated and graded subjectively.
  
  
  RESULTS
  The study evaluated 100 eyes of 50 patients ranging from 61 to 80 years. Postoperatively, there were no statistically significant differences in PCO between Group A and Group B at 1 year (0.06 ± 0.12 [SD] and 0.07 ± 0.13, respectively; P = 4.35) or 3 years (0.23 ± 0.36 and 0.22 ± 0.32, respectively; P = .66). In Group A and Group B, ACO was present in 18.0% of eyes and 2.7% of eyes, respectively, at 1 year (P = .03) and in 92.0% and 24.0%, respectively, at 3 years (P < .01). Capsule phimosis (18.0% at 1 year; 30.0% at 3 years) and glistenings (66.0% at 1 year; 86.0% at 3 years) were observed in Group A only.
  
  
  CONCLUSIONS
  Both IOLs had similarly low PCO rates 3 years postoperatively, although more ACO and capsule retraction were observed in eyes with the interrupted optic edge IOL.
authors.affiliation: From the Academic Teaching Hospital of St. John, Vienna, Austria. Electronic address: kahraman@gmx.at.
authors.forename: Guenal
authors.initials: G
authors.lastname: Kahraman
authors.affiliation: From the Academic Teaching Hospital of St. John, Vienna, Austria.
authors.forename: Michael
authors.initials: M
authors.lastname: Amon
authors.affiliation: From the Academic Teaching Hospital of St. John, Vienna, Austria.
authors.forename: Clara
authors.initials: C
authors.lastname: Ferdinaro
authors.affiliation: From the Academic Teaching Hospital of St. John, Vienna, Austria.
authors.forename: Karl
authors.initials: K
authors.lastname: Nigl
authors.affiliation: From the Academic Teaching Hospital of St. John, Vienna, Austria.
authors.forename: Michael
authors.initials: M
authors.lastname: Walch
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D000369:Aged, 80 and over; D057866:Anterior Capsule of the Lens / Q000473:pathology*; D058442:Capsule Opacification / Q000175:diagnosis / Q000453:epidemiology*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D057852:Posterior Capsule of the Lens / Q000473:pathology*; D011183:Postoperative Complications; D011446:Prospective Studies; D011474:Prosthesis Design
chemical_list: D000180:Acrylic Resins