title: Evaluation of three different agents for in-office treatment of dentinal hypersensitivity: a controlled clinical study.
abstract: BACKGROUND
  Dentin desensitizers are used for in-office treatment of dentinal hypersensitivity. They block the open tubules and bring about a reduction in hypersensitivity.
  
  
  OBJECTIVE
  The aim was to evaluate and compare the clinical effectiveness of a dentin desensitizer, a combination of a dentin desensitizer + adhesive and one-bottle self-etching adhesive for in-office treatment of dentin hypersensitivity.
  
  
  METHODS
  Institutional, prospective double-blind parallel clinical design.
  
  
  METHODS
  A total of 54 teeth in 20 patients were randomly allocated to one of the three study groups, with 18 teeth in each group as follows: Group A-Gluma Desensitizer (GD), Group B-Gluma Comfort Bond + Desensitizer (GCBD), Group C-Single Bond Universal (SBU). The patients' dentinal hypersensitivity scores for tactile (hand-held scratch device), thermal (cold), and evaporative (dental unit air syringe) stimuli were recorded on a visual analog scale. The parameters were recorded at baseline, immediately after application of the agent, 3- and 6-week posttreatment.
  
  
  METHODS
  The data were analyzed with Friedman's test, Wilcoxon signed ranks test, Kruskal-Wallis test, and Mann-Whitney-U-test (P < 0.05).
  
  
  RESULTS
  All three groups showed a significant reduction in dentinal hypersensitivity (P < 0.05) compared to baseline at all time intervals. Statistically, significant differences were noted between GD and SBU; between GCBD and SBU in all testing parameters. Between GD and GCBD no significant difference was noted.
  
  
  CONCLUSIONS
  GD and GCBD showed a greater reduction in dentin hypersensitivity than SBU.
authors.affiliation: Department of Operative Dentistry, SDM Dental College, Dharwad, Karnataka, India.
authors.forename: Shruti A
authors.initials: SA
authors.lastname: Patil
authors.forename: Balaram D
authors.initials: BD
authors.lastname: Naik
authors.forename: R
authors.initials: R
authors.lastname: Suma
mesh_terms: D000293:Adolescent; D000328:Adult; D017438:Bisphenol A-Glycidyl Methacrylate / Q000627:therapeutic use*; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000517:prevention & control*; D017220:Dentin-Bonding Agents / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005976:Glutaral / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008689:Methacrylates / Q000627:therapeutic use*; D011446:Prospective Studies
chemical_list: D057133:Dentin Desensitizing Agents; D017220:Dentin-Bonding Agents; C445022:Gluma Comfort Bond & Desensitizer; D008689:Methacrylates; C111486:gluma desensitizer; C115612:single bond; D017438:Bisphenol A-Glycidyl Methacrylate; D005976:Glutaral