title: Coproduct Promoted Povarov Reaction: Synthesis of Substituted Quinolines from Methyl Ketones, Arylamines, and α-Ketoesters.
abstract: A highly efficient I2-catalyzed Povarov-type reaction of methyl ketones, arylamines, and α-ketoesters is developed. This reaction utilizes a catalytic amount of HI coproduct as a promoter for the synthesis of substituted quinolones. This simple procedure represents an interesting new form of reactivity for the Povarov reaction with good functional group compatibility.
authors.forename: Qinghe
authors.initials: Q
authors.lastname: Gao
authors.forename: Shan
authors.initials: S
authors.lastname: Liu
authors.forename: Xia
authors.initials: X
authors.lastname: Wu
authors.forename: Jingjing
authors.initials: J
authors.lastname: Zhang
authors.forename: Anxin
authors.initials: A
authors.lastname: Wu
mesh_terms: D000096:Acetone / Q000737:chemistry; D004952:Esters; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009930:Organic Chemicals; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004952:Esters; D007659:Ketones; D009930:Organic Chemicals; D011804:Quinolines; D000096:Acetone