title: Pilot-scale subcritical solvent extraction of curcuminoids from Curcuma long L.
abstract: Curcuminoids consisted curcumin, demethoxycurcumin and bisdemethoxycurcumin, were extracted from turmeric using subcritical solvent by varying conditions of temperature (110-150 °C), time (1-10 min), pressure (5-100 atm), solid-to-solvent ratio, and mixing ratio of solvent. Preliminary lab-scale experiments were conducted to determine the optimum extraction temperature and mixing ratio of water and ethanol for the pilot-scale extraction. The maximum yield of curcuminoids in the pilot-scale system was 13.58% (curcumin 4.94%, demethoxycurcumin 4.73%, and bisdemethoxycurcumin 3.91% in dried extracts) at 135 °C/5 min with water/ethanol mixture (50:50, v/v) as a solvent. On the other hand, the extraction yields of curcuminoids were obtained as 10.49%, 13.71% and 13.96% using the 50%, 95% and 100% ethanol, respectively, at the atmospheric condition (60 °C/120 min). Overall results showed that the subcritical solvent extraction is much faster and efficient extraction method considering extracted curcuminoids contents and has a potential to develop a commercial process for the extraction of curcuminoids.
authors.affiliation: Department of Food Science and Engineering, Ewha Womans University, Seoul 120-750, South Korea.
authors.forename: Hye-Lim
authors.initials: HL
authors.lastname: Kwon
authors.affiliation: Department of Food Science and Engineering, Ewha Womans University, Seoul 120-750, South Korea. Electronic address: mschung@ewha.ac.kr.
authors.forename: Myong-Soo
authors.initials: MS
authors.lastname: Chung
mesh_terms: D002851:Chromatography, High Pressure Liquid; D003362:Cost-Benefit Analysis; D030024:Curcuma / Q000737:chemistry*; D003474:Curcumin / Q000031:analogs & derivatives* / Q000032:analysis; D036381:Diarylheptanoids; D000431:Ethanol / Q000737:chemistry; D006358:Hot Temperature; D010865:Pilot Projects; D010936:Plant Extracts / Q000032:analysis*; D012997:Solvents / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D036381:Diarylheptanoids; D010936:Plant Extracts; D012997:Solvents; D014867:Water; C034786:bisdemethoxycurcumin; D000431:Ethanol; D003474:Curcumin; C050229:demethoxycurcumin
keywords: Curcuminoids; Lab-scale system; Pilot-scale system; Subcritical solvent extraction; Turmeric