title: Psychotic experiences and risk of death in the general population: 24-27 year follow-up of the Epidemiologic Catchment Area study.
abstract: BACKGROUND
  Psychotic experiences are common in the general population and are associated with adverse psychiatric and social outcomes, even in the absence of a psychotic disorder.
  
  
  OBJECTIVE
  To examine the association between psychotic experiences and mortality over a 24-27 year period.
  
  
  METHODS
  We used data on 15 049 adult participants from four sites of the Epidemiologic Catchment Area baseline survey in the USA in the early 1980s, linked to the National Death Index and other sources of vital status up until 2007. Psychotic experiences were assessed by the Diagnostic Interview Schedule.
  
  
  RESULTS
  Lifetime psychotic experiences at baseline (n = 855; weighted prevalence, 5.5%) were significantly associated with all-cause mortality at follow-up after adjustment for sociodemographic characteristics and psychiatric diagnoses, including schizophrenia spectrum disorders (P<0.05). Baseline psychotic experiences were associated with over 5 years' shorter median survival time. Among the underlying causes of death, suicide had a particularly high hazard ratio (9.16, 95% CI 3.19-26.29).
  
  
  CONCLUSIONS
  Future research needs to explore the association of psychotic experiences with physical health and lifestyle factors that may mediate the relationship of psychotic experiences with mortality.
authors.affiliation: Vandad Sharifi, MD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA and Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran; William W. Eaton, PhD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Li Tzy Wu, ScD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina, USA; Kimberly B. Roth, MHS, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Bruce M. Burchett, PhD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina; Ramin Mojtabai, MD, PhD, MPH, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA vsharifi@jhsph.edu.
authors.forename: Vandad
authors.initials: V
authors.lastname: Sharifi
authors.affiliation: Vandad Sharifi, MD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA and Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran; William W. Eaton, PhD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Li Tzy Wu, ScD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina, USA; Kimberly B. Roth, MHS, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Bruce M. Burchett, PhD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina; Ramin Mojtabai, MD, PhD, MPH, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
authors.forename: William W
authors.initials: WW
authors.lastname: Eaton
authors.affiliation: Vandad Sharifi, MD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA and Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran; William W. Eaton, PhD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Li Tzy Wu, ScD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina, USA; Kimberly B. Roth, MHS, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Bruce M. Burchett, PhD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina; Ramin Mojtabai, MD, PhD, MPH, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
authors.forename: Li Tzy
authors.initials: LT
authors.lastname: Wu
authors.affiliation: Vandad Sharifi, MD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA and Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran; William W. Eaton, PhD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Li Tzy Wu, ScD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina, USA; Kimberly B. Roth, MHS, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Bruce M. Burchett, PhD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina; Ramin Mojtabai, MD, PhD, MPH, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
authors.forename: Kimberly B
authors.initials: KB
authors.lastname: Roth
authors.affiliation: Vandad Sharifi, MD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA and Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran; William W. Eaton, PhD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Li Tzy Wu, ScD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina, USA; Kimberly B. Roth, MHS, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Bruce M. Burchett, PhD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina; Ramin Mojtabai, MD, PhD, MPH, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
authors.forename: Bruce M
authors.initials: BM
authors.lastname: Burchett
authors.affiliation: Vandad Sharifi, MD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA and Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran; William W. Eaton, PhD, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Li Tzy Wu, ScD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina, USA; Kimberly B. Roth, MHS, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Bruce M. Burchett, PhD, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Duke University Medical Center, Durham, North Carolina; Ramin Mojtabai, MD, PhD, MPH, Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
authors.forename: Ramin
authors.initials: R
authors.lastname: Mojtabai
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002391:Catchment Area, Health / Q000706:statistics & numerical data*; D016021:Epidemiologic Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000401:mortality*; D012307:Risk Factors; D012559:Schizophrenia / Q000401:mortality*; D013406:Suicide, Attempted / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D014481:United States