title: Endoscopic treatment of gastroesophageal reflux disease.
abstract: Multiple new endoluminal devices and therapies have been devised to create a more effective antireflux barrier in patients with gastroesophageal reflux disease (GERD). Most of these therapies have been abandoned, because they were ineffective and/or had significant adverse effects. However, there are currently two therapies (Stretta, EsophyX) that have US Food and Drug Administration approval and continue to be used in select patients with GERD. The clinical management of GERD, disease complications, endoluminal techniques, evidence for efficacy, and controversies concerning endoluminal therapy for GERD are reviewed and discussed.
authors.affiliation: Department of Surgery, University of South Alabama College of Medicine, Mastin Building, 2451 Fillingim Street, Mobile, AL 36617, USA.
authors.forename: Kristin
authors.initials: K
authors.lastname: Hummel
authors.affiliation: Department of Surgery, University of South Alabama College of Medicine, Mastin Building, 2451 Fillingim Street, Mobile, AL 36617, USA. Electronic address: brichards@health.southalabama.edu.
authors.forename: William
authors.initials: W
authors.lastname: Richards
mesh_terms: D017130:Angioplasty / Q000379:methods; D017115:Catheter Ablation / Q000379:methods*; D004945:Esophagoscopy / Q000379:methods*; D018662:Fundoplication / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans; D016896:Treatment Outcome
keywords: Endoluminal devices; EsophyX; Gastroesophageal reflux disease; Stretta