title: Review of outcomes of atypical squamous cells of undetermined significance papanicolaou smears for 1991 and 1992, with follow-up through 1995.
abstract: OBJECTIVE
  Our aim was to review 1,754 consecutive Papanicolaou (Pap) smears from 1991 to 1992 to evaluate initial findings and disease progression through December of 1995.
  
  
  METHODS
  The study used analysis of data in the Gundersen Lutheran Medical Center Colposcopy Clinic's computerized registry. A total of 1,754 patients were followed, and findings were analyzed for progression and age-related outcomes.
  
  
  RESULTS
  At initial evaluation by a trained ACOG member colposcopist, 11% of patients with atypical squamous cells of undetermined significance (ASCUS) Pap smears had histologically confirmed cervical intraepithelial neoplasia (CIN) I lesion and 7% a CIN II or III lesion. After a negative initial evaluation for an ASCUS Pap smear, an additional 8.4% smears went on to to demonstrate histologically confirmed CIN II or III, and an additional 4.7% revealed a CIN I.
  
  
  CONCLUSIONS
  An ASCUS Pap smear requires evaluation by a care provider trained in colposcopy and management of abnormal Pap smears.
authors.affiliation: Department of Obstetrics and Gynecology, Gundersen and Lutheran Medical Center, La Crosse, WI.
authors.forename: J H
authors.initials: JH
authors.lastname: Gundersen
authors.forename: B L
authors.initials: BL
authors.lastname: Rooney
authors.forename: R L
authors.initials: RL
authors.lastname: Virata
authors.forename: S
authors.initials: S
authors.lastname: Bobenmeyer