title: Emerging Alternative Functions for the Auxiliary Subunits of the Voltage-Gated Calcium Channels.
abstract: Voltage gated calcium channels (Cav) are composed of up to five proteins: The ion conducting pore subunit α1 and the auxiliary subunits α2, δ, β, and γ. Recent reports show that Cavα1 and Cavβ comprise the calcium channel core complex and that β, α2 δ and γ may serve additional roles that are independent of the Cavα1 subunit. This short review will summarize these emerging functions.
authors.affiliation: Institut für Pharmakologie und Toxikologie, TU München, Biedersteiner Str. 29, 80802 München, Germany. Franz.Hofmann@mytum.de.
authors.forename: Franz
authors.initials: F
authors.lastname: Hofmann
authors.forename: Anouar
authors.initials: A
authors.lastname: Belkacemi
authors.forename: Veit
authors.initials: V
authors.lastname: Flockerzi
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D015640:Ion Channel Gating / Q000502:physiology*; D008954:Models, Biological; D018482:Muscle, Skeletal / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism; D011485:Protein Binding; D021122:Protein Subunits / Q000378:metabolism / Q000502:physiology
chemical_list: D015220:Calcium Channels; D021122:Protein Subunits; D002118:Calcium