title: What is the point of pseudokinases?
abstract: The interaction between an active kinase and an 'inactive' pseudokinase provides clues about how these enzymes were regulated in the past, and how this regulation has evolved.
authors.affiliation: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, United States.
authors.forename: Saravanan
authors.initials: S
authors.lastname: Raju
authors.affiliation: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, United States shaw@pathology.wustl.edu.
authors.forename: Andrey S
authors.initials: AS
authors.lastname: Shaw
mesh_terms: D000565:Ameloblasts / Q000378:metabolism*; D000818:Animals; D047389:Casein Kinase I / Q000235:genetics*; D003746:Dental Enamel Proteins / Q000235:genetics*; D016326:Extracellular Matrix Proteins / Q000235:genetics*; D005260:Female; D006801:Humans
chemical_list: D003746:Dental Enamel Proteins; D016326:Extracellular Matrix Proteins; D047389:Casein Kinase I
keywords: biochemistry; extracellular protein phosphorylation; human; kinase complex; mouse; pseudokinase; secretory pathway phosphorylation; tooth enamel formation