title: Breast cancer in young women in southern Tunisia: Anatomical study and clinical prognostic factors: About a series of 83 patients.
abstract: OBJECTIVE
  To define epidemiological, clinical, therapeutic and prognostic factors influencing survival of breast cancer in young women younger than 35 in southern Tunisia.
  
  
  METHODS
  This is a retrospective study of 83 patients younger than 35 years and treated within tumors mammary committee of Sfax.
  
  
  RESULTS
  The mean age was 31.7 years. T2 stage, high grade with positive node tumors were frequent. Breast surgery was performed for 73 patients. Chemotherapy was neo-adjuvant, adjuvant and palliative for respectively 10, 62 and 13 patients. Radiotherapy was delivered for 65 patients with curative intent and for 8 metastatic patients. Endocrine therapy was adjuvant in 38 patients and palliative in 6 cases. The overall survival (OS) at 5 years was 66.8%. Pejorative prognostic factors in uni-variate analysis were clinical T stage (T3, T4), and the number of involved lymph nodes.
  
  
  CONCLUSIONS
  Despite adequate treatment, the prognosis of breast cancer in young women remains worse. Early diagnosis is necessary to promote outcome.
authors.affiliation: Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia.
authors.forename: Mouna
authors.initials: M
authors.lastname: Kallel
authors.affiliation: Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia.
authors.forename: Fatma
authors.initials: F
authors.lastname: Elloumi
authors.affiliation: Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia ; Cytology and Pathology, Habib Bourguiba University Hospital, Sfax, Tunisia.
authors.forename: Abdelmajid
authors.initials: A
authors.lastname: Khabir
authors.affiliation: Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia.
authors.forename: Lilia
authors.initials: L
authors.lastname: Ghorbal
authors.affiliation: Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia.
authors.forename: Souhir
authors.initials: S
authors.lastname: Chaabouni
authors.affiliation: Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia ; Gynecology and Obstetric, Hedi Chaker University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia.
authors.forename: Habib
authors.initials: H
authors.lastname: Amouri
authors.affiliation: Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia ; Cytology and Pathology, Habib Bourguiba University Hospital, Sfax, Tunisia.
authors.forename: Mounir
authors.initials: M
authors.lastname: Frikha
authors.affiliation: Department of Oncology and Radiotherapy, Habib Bourguiba University Hospital, Ain Street km 0.5, Sfax 3000, Tunisia ; Medical Oncology, Habib Bourguiba University Hospital, Sfax, Tunisia.
authors.forename: Jamel
authors.initials: J
authors.lastname: Daoud
keywords: Breast; Cancer; Clinical; Prognosis; Young women