title: Demyelinating hypertrophic inferior alveolar nerve mimicking a nerve tumor.
abstract: We herein report a patient with demyelinating inferior alveolar nerve hypertrophy, which was initially suspected to have a nerve tumor. A 39-year-old woman with childhood-onset polyneuropathy presented with tooth pain and visited a dental clinic. An X-ray examination of the mandible revealed enlargement of the mandibular canal, and a nerve tumor was suspected. CT scan and MRI showed hypertrophy of the inferior alveolar nerve along its entire length. We diagnosed the patient with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), which was supported by the spontaneous recovery reported in her childhood, the results from a nerve conduction study and MRI data. CIDP should be considered in the differential diagnosis of mandibular canal enlargement.
authors.affiliation: Department of Neurology, Dokkyo Medical University, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Fujita
authors.forename: Norito
authors.initials: N
authors.lastname: Kokubun
authors.forename: Tsubasa
authors.initials: T
authors.lastname: Sada
authors.forename: Takahide
authors.initials: T
authors.lastname: Nagashima
authors.forename: Tomoko
authors.initials: T
authors.lastname: Komagamine
authors.forename: Kiyokazu
authors.initials: K
authors.lastname: Kawabe
authors.forename: Koichi
authors.initials: K
authors.lastname: Hirata
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008334:Mandible / Q000473:pathology*; D008340:Mandibular Nerve / Q000473:pathology / Q000503:physiopathology*; D009431:Neural Conduction; D011115:Polyneuropathies / Q000175:diagnosis* / Q000209:etiology; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000175:diagnosis* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed