title: A combination of alfaxalone and medetomidine followed by an alfaxalone continuous rate infusion in cynomolgus monkeys (Macaca fascicularis) undergoing pharmacoMRS.
authors.affiliation: Anaesthesia and Pain Therapy Division, Department of Clinical Veterinary Sciences, School of Veterinary Medicine, University of Berne, Berne, Switzerland. daniela.casoni@vetsuisse.unibe.ch.
authors.forename: Daniela
authors.initials: D
authors.lastname: Casoni
authors.affiliation: Department of Comparative Medicine, F. Hoffmann-La Roche AG, Basel, Switzerland.
authors.forename: Eva M
authors.initials: EM
authors.lastname: Amen
authors.affiliation: Department of Comparative Medicine, F. Hoffmann-La Roche AG, Basel, Switzerland.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Brecheisen
authors.affiliation: pRED, Pharma Research & Early Development, DTA Neuroscience, F. Hoffmann-La Roche AG, Basel, Switzerland.
authors.forename: Basil
authors.initials: B
authors.lastname: Kuennecke
authors.affiliation: pRED, Pharma Research & Early Development, DTA Neuroscience, F. Hoffmann-La Roche AG, Basel, Switzerland.
authors.forename: Thomas
authors.initials: T
authors.lastname: Müggler
authors.affiliation: Department of Comparative Medicine, F. Hoffmann-La Roche AG, Basel, Switzerland.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Bergadano
mesh_terms: D000758:Anesthesia / Q000662:veterinary; D000777:Anesthetics / Q000008:administration & dosage*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D006339:Heart Rate / Q000187:drug effects; D007260:Infusion Pumps / Q000662:veterinary; D007262:Infusions, Intravenous / Q000662:veterinary; D007273:Injections, Intramuscular / Q000662:veterinary; D008252:Macaca fascicularis / Q000502:physiology*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D020926:Medetomidine / Q000008:administration & dosage*; D011277:Pregnanediones / Q000008:administration & dosage*; D012119:Respiration / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D000777:Anesthetics; D018686:Anesthetics, Intravenous; D011277:Pregnanediones; C006477:alphaxalone; D020926:Medetomidine