title: Brief Report: Recent Infection, Sexually Transmitted Infections, and Transmission Clusters Frequently Observed Among Persons Newly Diagnosed With HIV in San Francisco.
abstract: There were 1311 newly diagnosed HIV cases in San Francisco between 2005 and 2011 that were linked to care at publicly funded facilities and had viral sequences available for analysis. Of the 214 cases characterized as recently infected with HIV at the time of diagnosis, 25% had a recent sexually transmitted infection diagnosis (vs. 10% among longer-standing HIV infections, P < 0.001) and 57% were part of a phylogenetic transmission cluster (vs. 42% among longer-standing HIV infection, P < 0.001). The association observed between recent HIV infection and having a sexually transmitted infection diagnosis during the interval overlapping likely HIV acquisition points to potential opportunities to interrupt HIV transmission.
authors.affiliation: *Department of Medicine, University of California, San Francisco, San Francisco, CA; †Gladstone Institute of Virology and Immunology, San Francisco, CA; ‡Department of Public Health, San Francisco, CA; and §San Francisco AIDS Foundation, San Francisco, CA.
authors.forename: Hong-Ha M
authors.initials: HM
authors.lastname: Truong
authors.forename: Sharon
authors.initials: S
authors.lastname: Pipkin
authors.forename: Kara J
authors.initials: KJ
authors.lastname: OʼKeefe
authors.forename: Brian
authors.initials: B
authors.lastname: Louie
authors.forename: Teri
authors.initials: T
authors.lastname: Liegler
authors.forename: Willi
authors.initials: W
authors.lastname: McFarland
authors.forename: Robert M
authors.initials: RM
authors.lastname: Grant
authors.forename: Kyle
authors.initials: K
authors.lastname: Bernstein
authors.forename: Susan
authors.initials: S
authors.lastname: Scheer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016000:Cluster Analysis; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000635:transmission*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012495:San Francisco / Q000453:epidemiology; D012749:Sexually Transmitted Diseases / Q000150:complications* / Q000175:diagnosis* / Q000453:epidemiology; D019562:Viral Load; D055815:Young Adult