title: The "peripheral washout sign" in focal hepatic lesions: not always an MRI sign of malignancy.
abstract: The "peripheral washout sign" is a magnetic resonance imaging finding defined as an enhancing liver lesion with a peripheral rim of de-enhancement relative to its center and surrounding parenchyma on delayed contrast-enhanced images. The "peripheral washout sign" has been described solely in malignant liver lesions. We present a histologically proven benign hepatic angiomyolipoma showing the "peripheral washout sign". To the best of our knowledge, this is the first report on a benign hepatic lesion exhibiting this extremely specific imaging feature.
authors.affiliation: Division of Body MRI, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA. Electronic address: falessan@bidmc.harvard.edu.
authors.forename: Francesco
authors.initials: F
authors.lastname: Alessandrino
authors.affiliation: Division of Body MRI, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.
authors.forename: Noam
authors.initials: N
authors.lastname: Millo
authors.affiliation: Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.
authors.forename: Eric U
authors.initials: EU
authors.lastname: Yee
authors.affiliation: Division of Body MRI, Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.
authors.forename: Koenraad J
authors.initials: KJ
authors.lastname: Mortelé
mesh_terms: D018207:Angiomyolipoma / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged
keywords: Benign hepatic tumor; Focal liver lesion; Hepatic epithelioid angiomyolipoma; MRI; Peripheral washout sign