title: DNA-Grafted Supramolecular Polymers: Helical Ribbon Structures Formed by Self-Assembly of Pyrene-DNA Chimeric Oligomers.
abstract: The controlled arraying of DNA strands on adaptive polymeric platforms remains a challenge. Here, the noncovalent synthesis of DNA-grafted supramolecular polymers from short chimeric oligomers is presented. The oligomers are composed of an oligopyrenotide strand attached to the 5'-end of an oligodeoxynucleotide. The supramolecular polymerization of these oligomers in an aqueous medium leads to the formation of one-dimensional (1D) helical ribbon structures. Atomic force and transmission electron microscopy show rod-like polymers of several hundred nanometers in length. DNA-grafted polymers of the type described herein will serve as models for the development of structurally and functionally diverse supramolecular platforms with applications in materials science and diagnostics.
authors.affiliation: Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, 3012 Bern (Switzerland).
authors.forename: Yuliia
authors.initials: Y
authors.lastname: Vyborna
authors.affiliation: Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, 3012 Bern (Switzerland).
authors.forename: Mykhailo
authors.initials: M
authors.lastname: Vybornyi
authors.affiliation: Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, 3012 Bern (Switzerland).
authors.forename: Alexander V
authors.initials: AV
authors.lastname: Rudnev
authors.affiliation: Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, 3012 Bern (Switzerland). robert.haener@dcb.unibe.ch.
authors.forename: Robert
authors.initials: R
authors.lastname: Häner
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D008958:Models, Molecular; D036103:Nanotechnology; D009690:Nucleic Acid Conformation; D058105:Polymerization; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry*
chemical_list: D011108:Polymers; D011721:Pyrenes; D004247:DNA; C030984:pyrene
keywords: DNA; nanotechnology; pyrene; self-assembly; supramolecular polymers