title: High risk of cerebrospinal fluid leakage in surgery of a rare primary intraosseous cavernous hemangioma of the clivus showing meningeal infiltration: A case report and review of the literature.
abstract: BACKGROUND
  Primary intraosseous cavernous hemangiomas (PICH) of the skull represent an infrequent bone tumor. Although some rare cases of PICHs located in the skull base have been published, to our concern only three cases have been reported in the English literature of PICHs arising within the clivus.
  
  
  METHODS
  We present the case of a patient presenting an isolated abducens paresis due to a rare PICH of the clivus showing also an unusual destruction of the inner table as well as infiltration of the dura mater. Due to this uncommon infiltrative pattern of an otherwise expected intraosseous tumor, a cerebrospinal fluid (CSF)-fistula occurred while performing a transnasal biopsy. The patient recovered successfully without need of lumbar drainage or re-surgery. Additionally, intratumoral decompression was sufficient to relief the abducens paresis.
  
  
  CONCLUSIONS
  Our case provides new and meaningful information about clinical features as well as growth pattern of these rare clival tumors. We also discuss the importance of knowing these peculiarities before surgery in order to plan the optimal operative management as well as to avoid complications while approaching PICHs localized in such a delicate cranial region.
authors.affiliation: Department of Neurosurgery, Sana Offenbach Hospital, University of Frankfurt am Main affiliated Hospitals, Starkenburgringstr. 66, 63069 Offenbach am Main, Germany.
authors.forename: Lucas
authors.initials: L
authors.lastname: Serrano
authors.affiliation: Department of Neurosurgery, Sana Offenbach Hospital, University of Frankfurt am Main affiliated Hospitals, Starkenburgringstr. 66, 63069 Offenbach am Main, Germany.
authors.forename: Eleftherios
authors.initials: E
authors.lastname: Archavlis
authors.affiliation: Department of Neurosurgery, Sana Offenbach Hospital, University of Frankfurt am Main affiliated Hospitals, Starkenburgringstr. 66, 63069 Offenbach am Main, Germany.
authors.forename: Elke
authors.initials: E
authors.lastname: Januschek
authors.affiliation: Department of Neurosurgery, Sana Offenbach Hospital, University of Frankfurt am Main affiliated Hospitals, Starkenburgringstr. 66, 63069 Offenbach am Main, Germany.
authors.forename: Peter T
authors.initials: PT
authors.lastname: Ulrich
keywords: Clivus; cavernous hemangioma; cerebrospinal fluid leakage