title: Genetic tests to identify risk for breast cancer.
abstract: OBJECTIVE
  To describe the currently available genetic tests that identify hereditary risk for breast cancer.
  
  
  METHODS
  Systematic review of scientific literature, clinical practice guidelines, and data published by test manufacturers.
  
  
  CONCLUSIONS
  Changes in gene patent laws and advances in sequencing technologies have resulted in rapid expansion of genetic testing. While BRCA1/2 are the most recognized genes linked to breast cancer, several laboratories now offer multi-gene panels to detect many risk-related mutations.
  
  
  CONCLUSIONS
  Genetic testing will be increasingly important in the prevention, diagnosis, and treatment of breast cancer. Oncology and advanced practice nurses must understand risk factors, significance of various genetic tests, and patient counseling.
authors.forename: Julie A
authors.initials: JA
authors.lastname: Lynch
authors.forename: Vickie
authors.initials: V
authors.lastname: Venne
authors.forename: Brygida
authors.initials: B
authors.lastname: Berse
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000235:genetics* / Q000451:nursing; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006801:Humans; D009859:Oncology Nursing / Q000379:methods*; D018570:Risk Assessment; D012307:Risk Factors
keywords: BRCA; Breast genetic testing; genetic risk; hereditary risk; multigene panels