title: Relationship between severity of pulmonary hypertension and coronary sinus diameter.
abstract: OBJECTIVE
  We investigated the relationship between coronary sinus (CS) diameter and pulmonary artery systolic pressure (PASP) in patients with pulmonary hypertension (PH) and normal left ventricular systolic function.
  
  
  METHODS
  A total of 155 participants referred for transthoracic echocardiography were included in the study. The study population consisted of 100 patients with chronic PH and 55 control subjects. Patients with PH were divided into two groups according to PASP: those with PASP 36-45 mmHg, the mild PH group (n=53); and those with PASP >45 mmHg, the moderate to severe PH group (n=47). CS diameter was measured from the posterior atrioventricular groove in apical 4-chamber view during ventricular systole according to the formula: mean CS=(proximal CS+mid CS+distal CS)/3.
  
  
  RESULTS
  Mean CS diameter was significantly higher in the moderate to severe PH group than in the controls and in the mild PH group (1.12±0.2 cm vs. 0.82±0.1 cm and 0.87±0.1 cm, respectively; p<0.001). It was significantly correlated with right atrial (RA) area (r=0.674, p<0.001), RA pressure (r=0.458, p<0.001), PASP (r=0.562, p<0.001), inferior vena cava diameter (r=0.416, p<0.001), right ventricular E/A ratio (r=-0.290, p<0.001), and E/Em ratio (r=0.235, p=0.004). RA area (β=0.475, p<0.001) and PASP (β=0.360, p=0.002) were found to be independent predictors of CS diameter.
  
  
  CONCLUSIONS
  A dilated CS was associated with moderate to severe pulmonary hypertension, and RA area and PASP were independent predictors of CS diameter.
authors.affiliation: Adiyaman University, School of Medicine, Department of Cardiology, Adiyaman, Turkey. Electronic address: drmcetin@gmail.com.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cetin
authors.affiliation: Adiyaman University, School of Medicine, Department of Cardiology, Adiyaman, Turkey.
authors.forename: Musa
authors.initials: M
authors.lastname: Cakici
authors.affiliation: Kahramanmaras State Hospital, Department of Cardiology, Kahramanmaras, Turkey.
authors.forename: Cemil
authors.initials: C
authors.lastname: Zencir
authors.affiliation: Adiyaman University, School of Medicine, Department of Cardiology, Adiyaman, Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Tasolar
authors.affiliation: Adiyaman University, School of Medicine, Department of Pulmonary Medicine, Adiyaman, Turkey.
authors.forename: Ercan
authors.initials: E
authors.lastname: Cil
authors.affiliation: Kahramanmaras State Hospital, Department of Cardiology, Kahramanmaras, Turkey.
authors.forename: Emrah
authors.initials: E
authors.lastname: Yıldız
authors.affiliation: Adiyaman University, School of Medicine, Department of Cardiology, Adiyaman, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Balli
authors.affiliation: Adiyaman University, School of Medicine, Department of Cardiology, Adiyaman, Turkey.
authors.forename: Sabri
authors.initials: S
authors.lastname: Abus
authors.affiliation: Adiyaman University, School of Medicine, Department of Cardiology, Adiyaman, Turkey.
authors.forename: Erdal
authors.initials: E
authors.lastname: Akturk
mesh_terms: D000368:Aged; D054326:Coronary Sinus / Q000000981:diagnostic imaging / Q000473:pathology*; D003430:Cross-Sectional Studies; D004452:Echocardiography; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D012720:Severity of Illness Index
keywords: Coronary sinus; Doppler tecidular onda de pulso; Hipertensão pulmonar; Pulmonary hypertension; Pulsed-wave tissue Doppler; Right atrial area; Seio coronário; Área auricular direita