title: Relationship between bone density and bone metabolism in adolescent idiopathic scoliosis.
abstract: Several authors have confirmed that 27 to 38% of AIS patients had osteopenia. But few studies have assessed bone metabolism in AIS. This study assessed bone mineral density and bone metabolism in AIS patients using the bone metabolism markers, BAP and TRAP5b. The subjects were 49 consecutive adolescent AIS patients seen at our institutes between March 2012 and September 2013. Sixty-five percent of AIS patients had osteopenia or osteoporosis and 59% of AIS patients had high values for TRAP5b. The AIS patients with high values of TRAP5b had lower Z scores than those with normal values of TRAP5b. Higher rates of bone resorption are associated with low bone density in AIS patients.
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University Medical Center, 4-57 Urafune Minami-ku, Yokohama, Kanagawa 232-0024 Japan.
authors.forename: Ko
authors.initials: K
authors.lastname: Ishida
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City Brain and Stroke Center, 1-2-1 Takigashira Isogo-ku, Yokohama, Kanagawa 235-0012 Japan.
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Aota
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University Medical Center, 4-57 Urafune Minami-ku, Yokohama, Kanagawa 232-0024 Japan.
authors.forename: Naoto
authors.initials: N
authors.lastname: Mitsugi
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City Brain and Stroke Center, 1-2-1 Takigashira Isogo-ku, Yokohama, Kanagawa 235-0012 Japan.
authors.forename: Motonori
authors.initials: M
authors.lastname: Kono
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University, 3-9 Fukuura Kanazawa-ku, Yokohama, Kanagawa 236-0004 Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Higashi
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City Brain and Stroke Center, 1-2-1 Takigashira Isogo-ku, Yokohama, Kanagawa 235-0012 Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Kawai
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University, 3-9 Fukuura Kanazawa-ku, Yokohama, Kanagawa 236-0004 Japan.
authors.forename: Katsutaka
authors.initials: K
authors.lastname: Yamada
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City Brain and Stroke Center, 1-2-1 Takigashira Isogo-ku, Yokohama, Kanagawa 235-0012 Japan.
authors.forename: Takanori
authors.initials: T
authors.lastname: Niimura
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University, 3-9 Fukuura Kanazawa-ku, Yokohama, Kanagawa 236-0004 Japan.
authors.forename: Kanichiro
authors.initials: K
authors.lastname: Kaneko
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University, 3-9 Fukuura Kanazawa-ku, Yokohama, Kanagawa 236-0004 Japan.
authors.forename: Hironori
authors.initials: H
authors.lastname: Tanabe
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University Medical Center, 4-57 Urafune Minami-ku, Yokohama, Kanagawa 232-0024 Japan.
authors.forename: Yohei
authors.initials: Y
authors.lastname: Ito
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University Medical Center, 4-57 Urafune Minami-ku, Yokohama, Kanagawa 232-0024 Japan.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Katsuhata
authors.affiliation: Department of Orthopaedic Surgery, Yokohama City University, 3-9 Fukuura Kanazawa-ku, Yokohama, Kanagawa 236-0004 Japan.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Saito