title: [History of cancer and chemotherapy before chemotherapy].
abstract: Chemotherapy stands today for cancer. In 1909, Paul Ehrlich (1854-1915) advocates the use of arsphenamine by infusion. So, he is considered as the father of chemotherapy. In fact, the first to have thought through chemotherapy was Sir Christopher Wren (1632-1723). In 1676, ideas and experiments on animals had sufficiently progressed to allow Michel Ettmuller (1644-1683) to publish the first edition of his book and several others were printed until 1753. In this book, he describes the first intravenous treatment, it sets the first indications, dosages and different products which can be used. However this method has been forgotten until the late 19th century.
authors.forename: Philippe
authors.initials: P
authors.lastname: Bonnichon
authors.forename: J P
authors.initials: JP
authors.lastname: Berger
authors.forename: N
authors.initials: N
authors.lastname: Bonni
authors.forename: M
authors.initials: M
authors.lastname: Fontaine
authors.forename: J
authors.initials: J
authors.lastname: Pion-Graff
mesh_terms: D061605:Administration, Intravenous; D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000266:history*; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000266:history*
chemical_list: D000970:Antineoplastic Agents