title: Structural Characterization of Methylenedianiline Regioisomers by Ion Mobility-Mass Spectrometry, Tandem Mass Spectrometry, and Computational Strategies. 2. Electrospray Spectra of 3-Ring and 4-Ring Isomers.
abstract: Building on results from our previous study of 2-ring methylenedianiline (MDA), a combined mass spectrometry approach utilizing ion mobility-mass spectrometry (IM-MS) and tandem mass spectrometry (MS/MS) coupled with computational methods enables the structural characterization of purified 3-ring and 4-ring MDA regioisomers in this current study. The preferred site of protonation for the 3-ring and 4-ring MDA was determined to be on the amino groups. Additionally, the location of the protonated amine along the MDA multimer was found to influence the gas phase stability of these molecules. Fragmentation mechanisms similar to the 2-ring MDA species were observed for both the 3-ring and 4-ring MDA. The structural characterization of 3-ring and 4-ring MDA isomers using modern MS techniques may aid polyurethane synthesis by the characterization of industrial grade MDA, multimeric MDA species, and methylene diphenyl diisocyanate (MDI) mixtures.
authors.affiliation: ∥Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
authors.forename: Sarah M
authors.initials: SM
authors.lastname: Stow
authors.affiliation: ∥Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
authors.forename: Tiffany M
authors.initials: TM
authors.lastname: Onifer
authors.affiliation: ∥Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
authors.forename: Jay G
authors.initials: JG
authors.lastname: Forsythe
authors.affiliation: #Bayer MaterialScience AG, 51368 Leverkusen, North Rhine-Westphalia, Germany.
authors.forename: Hartmut
authors.initials: H
authors.lastname: Nefzger
authors.affiliation: ∥Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
authors.forename: Nicholas W
authors.initials: NW
authors.lastname: Kwiecien
authors.affiliation: ∥Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
authors.forename: Jody C
authors.initials: JC
authors.lastname: May
authors.affiliation: ∥Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
authors.forename: John A
authors.initials: JA
authors.lastname: McLean
authors.affiliation: ∥Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
authors.forename: David M
authors.initials: DM
authors.lastname: Hercules
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D003198:Computer Simulation; D015394:Molecular Structure; D021241:Spectrometry, Mass, Electrospray Ionization; D013237:Stereoisomerism; D053719:Tandem Mass Spectrometry; D001559:Benzhydryl Compounds
chemical_list: D000814:Aniline Compounds; C009505:4,4'-diaminodiphenylmethane; D001559:Benzhydryl Compounds