title: Gabapentin and pregabalin: hepatic and haematological toxicity.
abstract: A review of pharmacovigilance data collected in France has shown that gabapentin and pregabalin are associated with serious and sometimes fatal hepatic and haematological disorders.
mesh_terms: D000588:Amines / Q000009:adverse effects*; D000700:Analgesics / Q000009:adverse effects; D056486:Chemical and Drug Induced Liver Injury / Q000453:epidemiology / Q000209:etiology*; D003509:Cyclohexanecarboxylic Acids / Q000009:adverse effects*; D005602:France / Q000453:epidemiology; D000077206:Gabapentin; D006402:Hematologic Diseases / Q000139:chemically induced* / Q000453:epidemiology; D006801:Humans; D060735:Pharmacovigilance; D000069583:Pregabalin; D012720:Severity of Illness Index; D005680:gamma-Aminobutyric Acid / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D000588:Amines; D000700:Analgesics; D003509:Cyclohexanecarboxylic Acids; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid; D000077206:Gabapentin