title: [Prevalence, associated factors and phenomenology of psychosis in patients with Parkinson's disease].
abstract: BACKGROUND
  Psychosis associated with Parkinson's disease is a major neuropsychiatric complication; it has been reported that 60% of patients will develop psychosis during the disease evolution. Its pathophysiology is multifactorial and clinically psychotic phenomena include minor hallucinations and confusional states.
  
  
  METHODS
  We performed a cross-sectional study in patients with Parkinson's disease from a tertiary hospital using a thoughtful neurological and neuropsychiatric evaluation along with specific scales for non-motor symptoms, depression, cognition, and presence and severity of psychotic symptoms and hallucinations.
  
  
  RESULTS
  We included a total of 236 patients with Parkinson's disease, of which 33 (13.9%) patients met the criteria for psychosis at the time of the evaluation. Visual hallucinations were the most common symptom. Age (p = 0.004), age at onset of the disease (p = 0.007) and its duration (p = 0.004), use of levodopa (p = 0.02), and use of amantadine (p = 0.004) were the main factors associated with the presence of psychosis.
  
  
  CONCLUSIONS
  Psychosis in Parkinson's disease is a relatively common manifestation and is mainly associated with clinical and demographic factors. Early recognition will optimize management and improve the quality of life of patients and their caregivers.
authors.affiliation: Laboratorio Clínico de Enfermedades Neurodegenerativas, Instituto Nacional de Neurología y Neurocirugía, México, D.F., Mexico.|Clínica de Movimientos Anormales, Instituto Nacional de Neurología y Neurocirugía, México, D.F., Mexico.
authors.forename: Mayela
authors.initials: M
authors.lastname: Rodríguez-Violante
authors.affiliation: Laboratorio Clínico de Enfermedades Neurodegenerativas, Instituto Nacional de Neurología y Neurocirugía, México, D.F., Mexico.|Clínica de Movimientos Anormales, Instituto Nacional de Neurología y Neurocirugía, México, D.F., Mexico.
authors.forename: Salvador
authors.initials: S
authors.lastname: Velázquez-Osuna
authors.affiliation: Laboratorio Clínico de Enfermedades Neurodegenerativas, Instituto Nacional de Neurología y Neurocirugía, México, D.F., Mexico.
authors.forename: Amin
authors.initials: A
authors.lastname: Cervantes-Arriaga
authors.affiliation: Laboratorio Clínico de Enfermedades Neurodegenerativas, Instituto Nacional de Neurología y Neurocirugía, México, D.F., Mexico.
authors.forename: Teresa
authors.initials: T
authors.lastname: Corona-Vázquez
authors.affiliation: Laboratorio de Psiquiatría Experimental, Instituto Nacional de Neurología y Neurocirugía, México, D.F., Mexico.
authors.forename: Camilo
authors.initials: C
authors.lastname: de la Fuente-Sandoval
mesh_terms: D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology; D015995:Prevalence; D011618:Psychotic Disorders / Q000209:etiology*