title: Modulation of immune response by organophosphorus pesticides: fishes as a potential model in immunotoxicology.
abstract: Immune response is modulated by different substances that are present in the environment. Nevertheless, some of these may cause an immunotoxic effect. In this paper, the effect of organophosphorus pesticides (frequent substances spilled in aquatic ecosystems) on the immune system of fishes and in immunotoxicology is reviewed. Furthermore, some cellular and molecular mechanisms that might be involved in immunoregulation mechanisms of organophosphorus pesticides are discussed.
authors.affiliation: Universidad Autónoma de Nayarit, Secretaría de Investigación y Posgrado, Laboratorio de Inmunotoxicología, Ciudad de la Cultura s/n, 63000 Tepic, NAY, Mexico.
authors.forename: K J G
authors.initials: KJ
authors.lastname: Díaz-Resendiz
authors.affiliation: Universidad Autónoma de Nayarit, Secretaría de Investigación y Posgrado, Laboratorio de Inmunotoxicología, Ciudad de la Cultura s/n, 63000 Tepic, NAY, Mexico.
authors.forename: G A
authors.initials: GA
authors.lastname: Toledo-Ibarra
authors.affiliation: Universidad Autónoma de Nayarit, Secretaría de Investigación y Posgrado, Laboratorio de Inmunotoxicología, Ciudad de la Cultura s/n, 63000 Tepic, NAY, Mexico.
authors.forename: M I
authors.initials: MI
authors.lastname: Girón-Pérez
mesh_terms: D056704:Adaptive Immunity / Q000187:drug effects* / Q000276:immunology; D000383:Agriculture / Q000379:methods; D000818:Animals; D016207:Cytokines / Q000096:biosynthesis / Q000235:genetics; D004195:Disease Models, Animal; D004781:Environmental Exposure / Q000009:adverse effects; D005399:Fishes / Q000276:immunology*; D007113:Immunity, Innate / Q000187:drug effects* / Q000276:immunology; D009943:Organophosphorus Compounds / Q000633:toxicity*; D010575:Pesticides / Q000633:toxicity*; D015398:Signal Transduction / Q000187:drug effects / Q000276:immunology
chemical_list: D016207:Cytokines; D009943:Organophosphorus Compounds; D010575:Pesticides