title: Long survival with erlotinib as second line treatment in non-small cell lung cancer.
abstract: Male, of 69 years old, caucasian, farmer, non smoker, with hypertension, dyslipidemia and past pesticide exposition, without known familiar diseases. In October/2005, he initiated dyspnoea and asthenia for moderate efforts, cough and night sibling, with persisted although several antibiotic treatments were done. In December/2005, he went to the Emergency department, where it was seen a right pleural effusion. The pleural liquid study, the bronchofiberscope examination, the biopsy and the studies for cancer staging allowed the diagnosis: Lung Adenocarcinoma stage IIIB (positive pleural effusion) - December 2005. He was submitted to thoracocentesis, pleurodesis and local radiotherapy. He carried through citostatic treatment with Gemcitabine-Carboplatin from 16/02/2006 to 13/07/2006, with some haematological toxicity. The follow up showed progression disease, initiating second line of treatment with Erlotinib 150mg, at 21/08/2006. He maintains the same treatment with disease stability and a general good condition, only showing a grade II rash (face, forearms and hands) as secondary effect of treatment. Rev Port Pneumol 2008; XIV (Supl 3): S83-S86.
authors.affiliation: Interna Complementar, Serviço de Medicina Interna 1 - Unidade de Oncologia,Hospital Infante D. Pedro - Aveiro - Portugal.
authors.forename: Mariana
authors.initials: M
authors.lastname: Sousa
authors.affiliation: Assistente Hospitalar, Serviço de Medicina Interna 1 - Unidade de Oncologia,Hospital Infante D. Pedro - Aveiro - Portugal.
authors.forename: Susana
authors.initials: S
authors.lastname: Cavadas
authors.affiliation: Assistente Hospitalar, Serviço de Medicina Interna 1 - Unidade de Oncologia,Hospital Infante D. Pedro - Aveiro - Portugal.
authors.forename: Maria José
authors.initials: MJ
authors.lastname: Moreira
authors.affiliation: Assistente Hospitalar, Serviço de Medicina Interna 1 - Unidade de Oncologia,Hospital Infante D. Pedro - Aveiro - Portugal.
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Mellidez
keywords: Lung cancer; Neoplasia do pulmão; adenocarcinoma; carboplatin; erlotinib; gemcitabine; primeira linha de tratamento; tratamento com erlotinib