title: Exercise training modifies gut microbiota in normal and diabetic mice.
abstract: Cecal microbiota from type 2 diabetic (db/db) and control (db/(+)) mice was obtained following 6 weeks of sedentary or exercise activity. qPCR analysis revealed a main effect of exercise, with greater abundance of select Firmicutes species and lower Bacteroides/Prevotella spp. in both normal and diabetic exercised mice compared with sedentary counterparts. Conversely, Bifidobacterium spp. was greater in exercised normal but not diabetic mice (exercise × diabetes interaction). How exercise influences gut microbiota requires further investigation.
authors.affiliation: a Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 1N4, Canada.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Lambert
authors.affiliation: a Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 1N4, Canada.
authors.forename: Jason P
authors.initials: JP
authors.lastname: Myslicki
authors.affiliation: a Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 1N4, Canada.
authors.forename: Marc R
authors.initials: MR
authors.lastname: Bomhof
authors.affiliation: a Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 1N4, Canada.
authors.forename: Darrell D
authors.initials: DD
authors.lastname: Belke
authors.affiliation: a Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 1N4, Canada.|b Department of Biochemistry and Molecular Biology, Cumming School of Medicine; University of Calgary, Calgary, AB T2N 4N1, Canada.
authors.forename: Jane
authors.initials: J
authors.lastname: Shearer
authors.affiliation: a Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 1N4, Canada.|b Department of Biochemistry and Molecular Biology, Cumming School of Medicine; University of Calgary, Calgary, AB T2N 4N1, Canada.
authors.forename: Raylene A
authors.initials: RA
authors.lastname: Reimer
mesh_terms: D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000382:microbiology*; D004195:Disease Models, Animal; D000069196:Gastrointestinal Microbiome; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D010805:Physical Conditioning, Animal / Q000706:statistics & numerical data*
keywords: diabetes; diabète; exercice physique; exercise; flore; microbiota