title: Mycotic aneurysm caused by Graphium species in a dog.
abstract: A 10-year-old castrated male mixed-breed dog exhibited vomiting, lethargy and anorexia. An abdominal ultrasound examination revealed a focal dilation of the abdominal aorta. The dog died 2 days after examination, and necropsy revealed a ruptured aneurysm at the abdominal aorta between the kidneys. Histological examination revealed severe granulomatous and necrotizing pan-arteritis with fungal organisms. Graphium species was identified through DNA sequence analysis of the PCR product from formalin-fixed paraffin-embedded samples. To our knowledge, this is the first report of aortic aneurysm caused by Graphium species in a dog. Sequence was submitted to the DNA Data Bank of Japan with the accession number LC007972.
authors.affiliation: Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
authors.forename: Yousuke
authors.initials: Y
authors.lastname: Murata
authors.forename: James Kenn
authors.initials: JK
authors.lastname: Chambers
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Uchida
authors.forename: Ko
authors.initials: K
authors.lastname: Nakashima
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Hanafusa
authors.forename: Mitsutaka
authors.initials: M
authors.lastname: Ikezawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Sugita
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakayama
mesh_terms: D000785:Aneurysm, Infected / Q000382:microbiology / Q000662:veterinary*; D000818:Animals; D001014:Aortic Aneurysm / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D001203:Ascomycota / Q000145:classification / Q000302:isolation & purification*; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D017809:Fatal Outcome; D008297:Male