title: Persistence of Ebola Virus in Ocular Fluid during Convalescence.
abstract: Among the survivors of Ebola virus disease (EVD), complications that include uveitis can develop during convalescence, although the incidence and pathogenesis of EVD-associated uveitis are unknown. We describe a patient who recovered from EVD and was subsequently found to have severe unilateral uveitis during convalescence. Viable Zaire ebolavirus (EBOV) was detected in aqueous humor 14 weeks after the onset of EVD and 9 weeks after the clearance of viremia.
authors.affiliation: From the Department of Medicine, Division of Infectious Diseases (J.B.V., C.S.K., G.M.L., A.K.M., B.S.R.), the Department of Ophthalmology (J.G.S., G.K., S.Y.), and the Department of Pathology and Laboratory Medicine (C.S.K.), Emory University School of Medicine, and the Centers for Disease Control and Prevention (M.H.K., S.W., U.S., T.M.U.) - both in Atlanta; the Infectious Diseases Institute, Mulago Hospital Complex, Kampala, Uganda (I.C.); and Flinders University, Adelaide, SA, Australia (J.R.S.).
authors.forename: Jay B
authors.initials: JB
authors.lastname: Varkey
authors.forename: Jessica G
authors.initials: JG
authors.lastname: Shantha
authors.forename: Ian
authors.initials: I
authors.lastname: Crozier
authors.forename: Colleen S
authors.initials: CS
authors.lastname: Kraft
authors.forename: G Marshall
authors.initials: GM
authors.lastname: Lyon
authors.forename: Aneesh K
authors.initials: AK
authors.lastname: Mehta
authors.forename: Gokul
authors.initials: G
authors.lastname: Kumar
authors.forename: Justine R
authors.initials: JR
authors.lastname: Smith
authors.forename: Markus H
authors.initials: MH
authors.lastname: Kainulainen
authors.forename: Shannon
authors.initials: S
authors.lastname: Whitmer
authors.forename: Ute
authors.initials: U
authors.lastname: Ströher
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Uyeki
authors.forename: Bruce S
authors.initials: BS
authors.lastname: Ribner
authors.forename: Steven
authors.initials: S
authors.lastname: Yeh
mesh_terms: D000328:Adult; D001082:Aqueous Humor / Q000821:virology*; D003289:Convalescence; D029043:Ebolavirus / Q000302:isolation & purification*; D005654:Fundus Oculi; D019142:Hemorrhagic Fever, Ebola / Q000150:complications*; D006801:Humans; D008297:Male; D015864:Panuveitis / Q000821:virology*; D014786:Vision Disorders / Q000821:virology*