title: Chronic whiplash pain.
abstract: Although most patients recover from acute whiplash injuries, those with chronic whiplash syndrome develop signs of central nervous system (CNS) amplification of pain and have a poor prognosis. In this context, specific pain generators from acute whiplash have been identified through clinical, biomechanical, and animal studies. This article gives a clinical perspective on current understanding of these pain generators, including the phenomenon of CNS sensitization.
authors.affiliation: Department of Rehabilitation Medicine, University of Washington, 1959 Northeast Pacific Street, Box 356490, Seattle, WA 98195, USA; Seattle Spine & Sports Medicine, 3213 Eastlake Avenue East, Suite A, Seattle, WA 98102, USA. Electronic address: res@seattlespine.com.
authors.forename: Richard
authors.initials: R
authors.lastname: Seroussi
authors.affiliation: Department of Rehabilitation Medicine, University of Washington, 1959 Northeast Pacific Street, Box 356490, Seattle, WA 98195, USA; Seattle Spine & Sports Medicine, 3213 Eastlake Avenue East, Suite A, Seattle, WA 98102, USA.
authors.forename: Virtaj
authors.initials: V
authors.lastname: Singh
authors.affiliation: Department of Rehabilitation Medicine, University of Washington, 1959 Northeast Pacific Street, Box 356490, Seattle, WA 98195, USA.
authors.forename: Adrielle
authors.initials: A
authors.lastname: Fry
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000503:physiopathology*; D059350:Chronic Pain / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D010147:Pain Measurement; D011379:Prognosis; D014911:Whiplash Injuries / Q000503:physiopathology* / Q000628:therapy
keywords: Chronic pain; Musculoskeletal; Neurologic; Physiatry; Review; Whiplash