title: Hematobiochemical evaluation of dermal subacute cypermethrin toxicity in buffalo calves.
abstract: Dermal exposure of cypermethrin, a type II synthetic pyrethroid insecticide, at dose rate of 0.25% for 14 consecutive days produced mild signs of toxicity in buffalo calves. It produced significant elevation in the levels of alanine aminotransferase (ALT; 39.5%), aspartate aminotransferase (AST; 32.0%), blood urea nitrogen (BUN; 57.7%), and plasma creatinine (30.0%). Cypermethrin also produced significant decrease in the hemoglobin (Hb) concentration (5.4%), packed cell volume (PCV; 3.4%), and total erythrocytic count (4.0%). Additionally, there was a significant increase in erythrocytic sedimentation rate (ESR; 3.1%). On the basis of the present study, it can be concluded that cypermethrin induces significant biochemical and hematological alterations in buffalo calves when exposed dermally.
authors.affiliation: Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India.
authors.forename: Shabir Ahmad
authors.initials: SA
authors.lastname: Dar
authors.affiliation: Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab, India.
authors.forename: Rajdeep
authors.initials: R
authors.lastname: Kaur
keywords: Biochemical; buffalo calves; cypermethrin; dermal; hematology; toxicity