title: Rapid Self-Integrating, Injectable Hydrogel for Tissue Complex Regeneration.
abstract: A novel rapid self-integrating, injectable, and bioerodible hydrogel is developed for bone-cartilage tissue complex regeneration. The hydrogels are able to self-integrate to form various structures, as can be seen after dying some hydrogel disks pink with rodamine. This hydrogel is demonstrated to engineer cartilage-bone complex.
authors.affiliation: Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, 710054, China.|Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI, 48109, USA.
authors.forename: Sen
authors.initials: S
authors.lastname: Hou
authors.affiliation: Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI, 48109, USA.
authors.forename: Xuefei
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI, 48109, USA.
authors.forename: Sean
authors.initials: S
authors.lastname: Park
authors.affiliation: Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI, 48109, USA.
authors.forename: Xiaobing
authors.initials: X
authors.lastname: Jin
authors.affiliation: Center for Biomedical Engineering and Regenerative Medicine, Frontier Institute of Science and Technology, Xi'an Jiaotong University, Xi'an, 710054, China.|Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI, 48109, USA.|Department of Biomedical Engineering, Macromolecular Science and Engineering Center, Department of Materials Science and Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
authors.forename: Peter X
authors.initials: PX
authors.lastname: Ma
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology; D055396:Bone Morphogenetic Protein 2 / Q000378:metabolism; D001861:Bone Regeneration; D002356:Cartilage / Q000502:physiology; D019902:Chondrocytes / Q000166:cytology / Q000378:metabolism / Q000637:transplantation; D003911:Dextrans / Q000737:chemistry; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry*; D051379:Mice; D012038:Regeneration; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism; D023822:Tissue Engineering; D054457:Tissue Scaffolds
chemical_list: C525719:Bmp2 protein, mouse; D055396:Bone Morphogenetic Protein 2; D003911:Dextrans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate
keywords: hydrogels; self-healing; supramolecular; tissue complex; tissue engineering