title: CT imaging spectrum and the histopathological features of adult metanephric adenoma.
abstract: OBJECTIVE
  To retrospectively evaluate the radiopathological features of adult metanephric adenoma (MA) and explore whether MA can be differentiated on CT images, including the basis of their morphological features and enhancement patterns.
  
  
  METHODS
  18 consecutive MA cases (age range, 18-66 years; 9 males and 9 females) were pathologically proven and recruited in our study between January 2004 and June 2014. Unenhanced and contrast-enhanced CT were performed and correlated with corresponding pathological findings to differentiate between MA and other renal tumours. The enhancement pattern, lesion contour and presence of calcifications were evaluated.
  
  
  RESULTS
  On unenhanced CT scan, the most common (n = 15, 83.3%) CT imaging characteristics were the presence of homogeneity and well-defined solid renal masses; the minority (n = 3, 16.7%) were heterogeneous or centrally located low-attenuation masses. Contrast-enhanced CT image revealed hypoattenuating heterogeneous masses with varying degrees of contrast enhancement in 16 (88.9%) cases, in contrast to those without increased attenuation in 2 (11.1%) cases. Scattered calcification was found only in one case (5.6%). Pathological results revealed that a total of 6 (33.3%) cases had concomitant malignant carcinoma components; 2 (11.1%) patients had malignant MA; and pure MA was found in 10 cases, with a surprisingly high proportion of malignant tumours.
  
  
  CONCLUSIONS
  The positive-predictive values of "high" enhancement seemed relatively characteristic for the diagnosis of malignant and composite MA.
  
  
  CONCLUSIONS
  Radiopathological features of adult MA and exploring whether MA can be differentiated on CT images, including the basis of their morphological features and enhancement patterns.
authors.affiliation: 1 Department of Urology, The second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin, China.
authors.forename: G
authors.initials: G
authors.lastname: Li
authors.affiliation: 2 Department of Radiology, The People's Hospital of Bin Zhou, Bin Zhou, China.
authors.forename: F
authors.initials: F
authors.lastname: Fu
authors.affiliation: 1 Department of Urology, The second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin, China.
authors.forename: H
authors.initials: H
authors.lastname: Song
authors.affiliation: 1 Department of Urology, The second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Niu
authors.affiliation: 3 Department of Urology, Tianjin Union Medicine Center, Tianjin, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Su
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002114:Calcinosis / Q000000981:diagnostic imaging; D003287:Contrast Media; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods; D055815:Young Adult
chemical_list: D003287:Contrast Media