title: Successful thrombolysis for acute ischaemic stroke in haemodialysis.
abstract: Stroke is a leading cause of death worldwide and is associated with significant morbidity in survivors. Early thrombolytic therapy in acute ischaemic stroke has been shown to dramatically improve patient outcomes. Although the age-adjusted incidence of stroke is 5-10 times greater in haemodialysis patients, the use of thrombolysis for this indication in this group of patients has not been described to date. We present a case where alteplase was used successfully for acute ischaemic stroke in a patient established on maintenance haemodialysis in the setting of an international randomized controlled trial and advocate caution with the use of systemic thrombolytics despite the favourable outcome seen with this case.
authors.affiliation: Haemodialysis Research Group, Imperial College Kidney and Transplant Institute, West London Renal and Transplant Centre , Hammersmith Hospital , London , UK.
authors.forename: Albert
authors.initials: A
authors.lastname: Power
authors.affiliation: Haemodialysis Research Group, Imperial College Kidney and Transplant Institute, West London Renal and Transplant Centre , Hammersmith Hospital , London , UK.
authors.forename: Steven
authors.initials: S
authors.lastname: Moser
authors.affiliation: Haemodialysis Research Group, Imperial College Kidney and Transplant Institute, West London Renal and Transplant Centre , Hammersmith Hospital , London , UK.
authors.forename: Neill
authors.initials: N
authors.lastname: Duncan
keywords: alteplase; haemodialysis; stroke