title: Uveitis in spondyloarthritis including psoriatic arthritis, ankylosing spondylitis, and inflammatory bowel disease.
abstract: Uveitis is a common complication of spondyloarthritis. The "phenotype" of the uveitis characteristic of ankylosing spondylitis (sudden onset, anterior, unilateral, recurrent, more often male) may differ from the phenotype often seen with either psoriatic arthritis or inflammatory bowel disease (insidious onset, anterior and intermediate, bilateral, chronic, and/or more often female). The frequency of uveitis is also much greater in association with ankylosing spondylitis than with either inflammatory bowel disease or psoriasis. Uveitis may affect the choice of therapy and can rarely be a complication of therapy. Uveitis and arthritis also co-exist in several animal models.
authors.affiliation: Casey Eye Institute, Oregon Health & Science University, 3181 SW San Jackson PK Rd, Portland, OR, 97239, USA, rosenbaj@ohsu.edu.
authors.forename: James T
authors.initials: JT
authors.lastname: Rosenbaum
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D015535:Arthritis, Psoriatic / Q000453:epidemiology*; D015897:Comorbidity; D015796:HLA-B27 Antigen / Q000235:genetics; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D015212:Inflammatory Bowel Diseases / Q000453:epidemiology*; D008727:Methotrexate / Q000627:therapeutic use; D025242:Spondylarthropathies / Q000453:epidemiology; D013167:Spondylitis, Ankylosing / Q000453:epidemiology*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors; D014605:Uveitis / Q000188:drug therapy / Q000453:epidemiology* / Q000235:genetics
chemical_list: D000305:Adrenal Cortex Hormones; D015796:HLA-B27 Antigen; D007166:Immunosuppressive Agents; D014409:Tumor Necrosis Factor-alpha; D008727:Methotrexate