title: Granulomatosis with polyangiitis presenting as a choroidal tumor.
abstract: Granulomatosis with polyangiitis (GPA) sometimes involves the eye orbit; however, choroidal involvements in GPA had been rarely reported. We report a rare case presenting with a choroidal mass in an 83-year-old Japanese woman who presented with left eye pain. Diagnostic biopsy revealed necrotizing vasculitis with infiltrates of inflammatory cells. Diagnosis was localized granulomatosis with polyangiitis. Combined treatments with corticosteroid plus azathioprine resolved the choroidal mass region. Although treatment with corticosteroid and immunosuppressive agents improves the prognosis of the disease, ocular morbidity is still well recognized. Clinicians should consider a differential diagnosis of GPA in patients with inflammatory choroidal tumors.
authors.affiliation: Departments of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Taro
authors.initials: T
authors.lastname: Masuda
authors.affiliation: Departments of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Yasumori
authors.initials: Y
authors.lastname: Izumi
authors.affiliation: Departments of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Hayato
authors.initials: H
authors.lastname: Takeshita
authors.affiliation: Departments of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Chieko
authors.initials: C
authors.lastname: Kawahara
authors.affiliation: Departments of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Yoshika
authors.initials: Y
authors.lastname: Tsuji
authors.affiliation: Department of Pathology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Kurohama
authors.affiliation: Departments of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Nozomi
authors.initials: N
authors.lastname: Iwanaga
authors.affiliation: Department of Ophthalmology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Miwako
authors.initials: M
authors.lastname: Inamoto
authors.affiliation: Department of Otolaryngology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Kase
authors.affiliation: Department of Pathology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ito
authors.affiliation: Department of Rheumatology, Nagasaki University Hospital, Sakamoto 1-7-1, Nagasaki 852-8501, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kawakami
authors.affiliation: Departments of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan.
authors.forename: Kiyosi
authors.initials: K
authors.lastname: Migita