title: Transhiatal Esophagectomy without Mediastinal Manipulation for Lower Third Esophageal and Cardial Cancers: The First Experience of a New Technique.
abstract: BACKGROUND
  Considering the poor survival rate of patients with esophageal cancers, mainly due to the disease effects and surgical co morbidities, we have aimed to introduce a new method of Transhiatal Esophagectomy (THE) without mediastinal manipulation for lower third esophageal and cardial cancers. It has suggested that using this technique would decrease mentioned complications.
  
  
  METHODS
  In this prospective study, patients with esophageal cancer who referred for surgical treatment have enrolled and undergone to new method of THE, without mediastinal manipulation. Pre and post-operative morbidities as well as the duration of procedure, duration of hospital and ICU stay have recorded. All patients have followed up or 4-40 months.
  
  
  RESULTS
  In this study 53 patients with mean age of 55.2+/-10.3 years have undergone esophagectomy, and then in 50 of them the new method has performed. Median operative time and volume of blood loss was 120 minutes and 130 ml, respectively. Median duration of hospital and ICU stay was 7 and 1 day, respectively. There were no Pre-operative mortalities, arrhythmia, hemodynamic instability and mediastinal vessels injury. The most common co morbidities have related to our new method were mediastinal pleura injury, anastomotic leaks and anastomotic narrowing with 20%, 16% and 10% reported rate, respectively.
  
  
  CONCLUSIONS
  The findings of current study have indicated that transhiatal esophagectomy without mediastinal manipulation, has represented a safe and effective method for treatment of lower third esophageal and cardial cancers due to its potential advantages of decreased blood loss, being a less traumatic procedure, minimal cardiopulmonary complications and low rate of hospital mortality.
authors.affiliation: Department of surgery, Isfahan University of Medical Science (IUMS), Isfahan, Iran.
authors.forename: Seyed Abbas
authors.initials: SA
authors.lastname: Tabatabaei
authors.affiliation: Department of surgery, Isfahan University of Medical Science (IUMS), Isfahan, Iran.
authors.forename: Seyed Mozafar
authors.initials: SM
authors.lastname: Hashemi
authors.affiliation: Department of surgery, Isfahan University of Medical Science (IUMS), Isfahan, Iran.
authors.forename: Behrooz
authors.initials: B
authors.lastname: Kelidari
keywords: Transhiatal Esophagectomy; arrhythmia; hypotension; morbidity