title: Prevalence of glucose intolerance at 6 weeks postpartum in Indian women with gestational diabetes mellitus.
abstract: OBJECTIVE
  Women with a history of gestational diabetes mellitus (GDM) have an increased risk for future glucose intolerance, and should be followed up with subsequent screening for the development of diabetes or pre-diabetes at 6-12 weeks postpartum. We studied the prevalence of glucose intolerance at 6 weeks postpartum in Indian women with GDM diagnosed according to ADA criteria.
  
  
  METHODS
  This longitudinal study, conducted at a tertiary care centre, included 75 Asian-Indian women aged ≥18 years, with a diagnosis of GDM (as per ADA criteria), who were referred to the Endocrine Department at Indraprastha Apollo Hospital, Delhi. A 2-h 75 g oral glucose tolerance test (OGTT) was performed at 6 weeks postpartum.
  
  
  RESULTS
  Out of the 75 women who had GDM and were recommended an OGTT at 6 weeks postpartum, 17.3% did not return for the test. Out of 62 women, one-third (33.8%) developed an abnormal OGTT at 6 weeks postpartum, while 66.1% had reverted to normal glucose tolerance. Impaired fasting glucose (IFG) was seen in 14.5%, 4.8% had impaired glucose tolerance (IGT), 8% had both IFG and IGT, and 6.4% had overt type 2 diabetes.
  
  
  CONCLUSIONS
  Our study emphasizes the need for compulsory follow up OGTT for women with GDM in our part of the world in view of ethnicity and prevailing socio-cultural factors.
authors.affiliation: Apollo Centre for Obesity, Diabetes and Endocrinology (ACODE), Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India. Electronic address: radhikajindal@gmail.com.
authors.forename: Radhika
authors.initials: R
authors.lastname: Jindal
authors.affiliation: Apollo Centre for Obesity, Diabetes and Endocrinology (ACODE), Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India.
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Siddiqui
authors.affiliation: Apollo Centre for Obesity, Diabetes and Endocrinology (ACODE), Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India.
authors.forename: Nitin
authors.initials: N
authors.lastname: Gupta
authors.affiliation: Apollo Centre for Obesity, Diabetes and Endocrinology (ACODE), Indraprastha Apollo Hospital, Sarita Vihar, New Delhi, India.
authors.forename: Subhash K
authors.initials: SK
authors.lastname: Wangnoo
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D016640:Diabetes, Gestational; D005260:Female; D018149:Glucose Intolerance / Q000453:epidemiology*; D005951:Glucose Tolerance Test; D006801:Humans; D007194:India; D008137:Longitudinal Studies; D049590:Postpartum Period; D011247:Pregnancy; D012307:Risk Factors; D012959:Socioeconomic Factors
keywords: Gestational diabetes; Postpartum; Type 2 diabetes