title: Pertussis Resurgence Associated with Pertactin-Deficient and Genetically Divergent Bordetella Pertussis Isolates in Israel.
abstract: The Bordetella pertussis polymerase chain reaction positivity rate changed after additional diphtheria-tetanus-acellular pertussis boosters in 2005 and 2008, 9.8%, 13.4%, 22% and 15.2% in 2010, 2011, 2012 and 2013, P < 0.001, respectively. New pulsed-field gel electrophoresis profiles were detected between 2009 and 2012. The proportion of pertactin-deficient isolates increased over time, 6.6% versus 7.1% versus 33.3% during 2005-2006, 2011-2012 and 2013-2014, P < 0.03, respectively.
authors.affiliation: From the *Clinical Microbiology Laboratory, Bnai Zion Medical Center, Haifa, Israel, †The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel; ‡Department of Pediatrics, Bnai Zion Medical Center, Haifa, Israel; and §Laboratory of Clinical Bacteriology, Rambam Medical Center, Haifa, Israel.
authors.forename: Ellen
authors.initials: E
authors.lastname: Bamberger
authors.forename: Bahaa
authors.initials: B
authors.lastname: Abu Raya
authors.forename: Lyora
authors.initials: L
authors.lastname: Cohen
authors.forename: Orit
authors.initials: O
authors.lastname: Golan-Shany
authors.forename: Sima
authors.initials: S
authors.lastname: Davidson
authors.forename: Yuval
authors.initials: Y
authors.lastname: Geffen
authors.forename: Isaac
authors.initials: I
authors.lastname: Srugo
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001886:Bordetella pertussis / Q000235:genetics*; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006801:Humans; D007557:Israel; D010566:Virulence Factors, Bordetella / Q000235:genetics*; D014917:Whooping Cough / Q000382:microbiology*
chemical_list: D001425:Bacterial Outer Membrane Proteins; D010566:Virulence Factors, Bordetella; C068929:pertactin