title: Autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination in Colombians: a call for personalised medicine.
abstract: This was a case study in which 3 patients with autoimmune/auto-inflammatory syndrome induced by adjuvants (ASIA) after quadrivalent human papillomavirus vaccination (HPV) were evaluated and described. All the patients were women. Diagnosis consisted of HLA-B27 enthesitis related arthritis, rheumatoid arthritis and systemic lupus erythematous, respectively. Our results highlight the risk of developing ASIA after HPV vaccination and may serve to increase the awareness of such a complication. Factors that are predictive of developing autoimmune diseases should be examined at the population level in order to establish preventive measures in at-risk individuals for whom healthcare should be personalized and participatory.
authors.affiliation: Centre for Autoimmune Diseases Research (CREA), Universidad del Rosario; and Mederi Hospital Universitario Mayor, Bogota, Colombia.
authors.forename: Juan-Manuel
authors.initials: JM
authors.lastname: Anaya
authors.affiliation: Centre for Autoimmune Diseases Research (CREA), Universidad del Rosario; and Mederi Hospital Universitario Mayor, Bogota, Colombia.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Reyes
authors.affiliation: Banco de Sangre, Tejidos y Células, Hemocentro Distrital, Secretaría de Salud de Bogota, Bogota, Colombia.
authors.forename: Ana M
authors.initials: AM
authors.lastname: Perdomo-Arciniegas
authors.affiliation: Banco de Sangre, Tejidos y Células, Hemocentro Distrital, Secretaría de Salud de Bogota, Bogota, Colombia.
authors.forename: Bernardo
authors.initials: B
authors.lastname: Camacho-Rodríguez
authors.affiliation: Centre for Autoimmune Diseases Research (CREA), Universidad del Rosario; and Mederi Hospital Universitario Mayor, Bogota, Colombia.
authors.forename: Adriana
authors.initials: A
authors.lastname: Rojas-Villarraga
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000009:adverse effects*; D000293:Adolescent; D018501:Antirheumatic Agents / Q000008:administration & dosage; D001171:Arthritis, Juvenile / Q000209:etiology / Q000276:immunology / Q000503:physiopathology / Q000628:therapy; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000209:etiology / Q000276:immunology / Q000503:physiopathology; D001323:Autoantibodies / Q000097:blood; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D015796:HLA-B27 Antigen / Q000097:blood; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy / Q000209:etiology / Q000276:immunology / Q000503:physiopathology; D030361:Papillomavirus Infections / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control*; D055815:Young Adult
chemical_list: D000276:Adjuvants, Immunologic; D018501:Antirheumatic Agents; D001323:Autoantibodies; D005938:Glucocorticoids; D015796:HLA-B27 Antigen; D053918:Papillomavirus Vaccines