title: One-pot synthesis of fluorescent DHLA-stabilized Cu nanoclusters for the determination of H2O2.
abstract: A facile one-pot approach has been developed to prepare orange-emitting Cu nanoclusters (NCs) using tetrakis(hydroxymethyl)phosphonium chloride as a reducing agent and lipoic acid as a capping agent under an alkaline medium at room temperature. The as-prepared Cu NCs exhibited excellent water solubility, large Stokes shift, long lifetime and good dispersion. After the addition of polyvinyl pyrrolidone, the fluorescence intensity of dihydrolipoic acid-stabilized Cu NCs (DHLA-Cu NCs) was greatly enhanced, and their fluorescence signal remained stable for 5 weeks storage in the dark at room temperature. Based on H2O2-induced fluorescence quenching, DHLA-Cu NCs showed high sensitivity and selectivity for the detection of H2O2 in aqueous solution with a detection limit of 0.3μM, and were applied successfully to the detection of H2O2 in human urine samples.
authors.affiliation: State Environmental Protection Key Laboratory of Drinking Water Source Management and Technology, Shenzhen Key Laboratory of Drinking Water Source Safety Control, Shenzhen Research Academy of Environmental Sciences, Shenzhen 518001, China.
authors.forename: Tingyao
authors.initials: T
authors.lastname: Zhou
authors.affiliation: Xiamen Huaxia College, Xiamen 361005, China.
authors.forename: Qiuhong
authors.initials: Q
authors.lastname: Yao
authors.affiliation: Xiamen Huaxia College, Xiamen 361005, China.
authors.forename: Tingting
authors.initials: T
authors.lastname: Zhao
authors.affiliation: State Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361005, China. Electronic address: xichen@xmu.edu.cn.
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
keywords: Cu nanoclusters; H(2)O(2) detection; One-pot synthesis; Polyvinyl pyrrolidone