title: Non-coding regions of the Ebola virus genome contain indispensable phylogenetic and evolutionary information.
abstract: We compared the numbers of nucleotide substitutions occurring in the non-coding regions and coding regions of Ebola virus genomes and found that non-coding regions contain indispensable phylogenetic and evolutionary information. The omission of genetic data from non-coding regions can lead to unreliable phylogenies and inaccurate estimates of evolutionary parameters.
authors.affiliation: School of Public Health, Taishan Medical College, Tai'an, 271000, China.
authors.forename: XinQuan
authors.initials: X
authors.lastname: Jiang
authors.forename: ZhenJie
authors.initials: Z
authors.lastname: Zhang
authors.forename: DongMing
authors.initials: D
authors.lastname: Zhuang
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Carr
authors.forename: RuiLing
authors.initials: R
authors.lastname: Zhang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Lv
authors.forename: WeiFeng
authors.initials: W
authors.lastname: Shi
mesh_terms: D029043:Ebolavirus / Q000235:genetics*; D019143:Evolution, Molecular; D016679:Genome, Viral; D010802:Phylogeny