title: Draft Genome Sequence of Mycobacterium tuberculosis Strain E186hv of Beijing B0/W Lineage with Reduced Virulence.
abstract: We report a draft genome sequence of Mycobacterium tuberculosis strain E186hv, belonging to the Beijing B0/W lineage and isolated from a patient from Kurgan, Russia. This clinical isolate showed a reduced virulence phenotype unusual for this lineage and resistance to isoniazid, rifampin, ethambutol, pyrazinamide, and ofloxacin. We analyzed single nucleotide polymorphisms (SNPs) associated with virulence.
authors.affiliation: Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Moscow, Russia.
authors.forename: K V
authors.initials: KV
authors.lastname: Shur
authors.affiliation: Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Moscow, Russia.
authors.forename: K M
authors.initials: KM
authors.lastname: Klimina
authors.affiliation: Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Moscow, Russia.
authors.forename: N V
authors.initials: NV
authors.lastname: Zakharevich
authors.affiliation: Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Moscow, Russia.
authors.forename: D A
authors.identifier: http://orcid.org/0000-0003-4296-5815
authors.initials: DA
authors.lastname: Maslov
authors.affiliation: Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Moscow, Russia.
authors.forename: O B
authors.identifier: http://orcid.org/0000-0003-2015-0025
authors.initials: OB
authors.lastname: Bekker
authors.affiliation: Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Moscow, Russia.
authors.forename: M V
authors.initials: MV
authors.lastname: Zaychikova
authors.affiliation: Ural Research Institute for Phthisiopulmonology, Ekaterinburg, Russia.
authors.forename: E Y
authors.initials: EY
authors.lastname: Kamaev
authors.affiliation: Ural Research Institute for Phthisiopulmonology, Ekaterinburg, Russia.
authors.forename: M A
authors.initials: MA
authors.lastname: Kravchenko
authors.affiliation: Ural Research Institute for Phthisiopulmonology, Ekaterinburg, Russia.
authors.forename: S N
authors.initials: SN
authors.lastname: Skornyakov
authors.affiliation: Department of Molecular Microbiology & Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Laboratory of Bacterial Genetics, Vavilov Institute of General Genetics, Moscow, Russia valerid@vigg.ru.
authors.forename: V N
authors.initials: VN
authors.lastname: Danilenko