title: [Post-hematopietic stem cell transplant complications].
abstract: Under the long-term monitoring of patients treated in childhood or adolescence for cancer, we present in this article the long-term monitoring and therefore possible effects of patients who underwent allergenic hematopoietic stem cell transplantation. This article is based on a collaborative effort organized by the French Society of Bone Marrow Transplantation and Cell Therapy (SFGM-TC), which took place during the 4th day of allograft harmonization practices. Patients affected are children and young adults (0-25 years). We defined the monitoring effects beyond 1 year post-transplant. Our recommendations are based on a literature review, in line with the Leucémie Enfant Adulte (LEA) study cohort of long-term monitoring of patients treated for hematological malignancies in childhood, grafted or not. It became important to determine the nature of problems, their risk factors, frequency and monitoring necessary to implement for their detection. We will not address the therapeutic management of sequelae.
authors.affiliation: Hôpital Jeanne-de-Flandre, unité d'hématologie pédiatrique, avenue Eugène-Avinée, 59037 Lille cedex, France. Electronic address: eva.deberranger@chru-lille.fr.
authors.forename: Eva
authors.initials: E
authors.lastname: de Berranger
authors.affiliation: Groupe hospitalier Pellegrin, hôpital des enfants, unité d'oncohématologie pédiatrique, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Jubert
authors.affiliation: AP-HM, hôpital d'enfant de la Timone, service d'hématologie et oncologie pédiatrique, boulevard Jean-Moulin, 13385 Marseille cedex 05, France; AP-HM, Aix-Marseille université, département d'épidémiologie et économie de la santé publique et des maladies chroniques et de la qualité de l'unité de recherche sur la vie (EA3279), SPMC EA3279, 13385 Marseille cedex 05, France.
authors.forename: Gérard
authors.initials: G
authors.lastname: Michel
mesh_terms: D000293:Adolescent; D000328:Adult; D064591:Allografts; D001847:Bone Diseases / Q000209:etiology; D001851:Bone Diseases, Metabolic / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D004700:Endocrine System Diseases / Q000209:etiology; D005500:Follow-Up Studies; D006331:Heart Diseases / Q000209:etiology; D019337:Hematologic Neoplasms / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007674:Kidney Diseases / Q000209:etiology; D008171:Lung Diseases / Q000209:etiology; D024821:Metabolic Syndrome / Q000209:etiology; D010020:Osteonecrosis / Q000209:etiology; D010024:Osteoporosis / Q000209:etiology; D012871:Skin Diseases / Q000209:etiology; D055815:Young Adult
keywords: Greffe de cellules souches hématopoïétiques; Hematopoietic stem cells transplantation; Long term; Long terme; Pediatrics; Pédiatrie; Sequelae; Survivants; Survivors; Séquelles