title: Men's Health Is Not Affected by Their Mothers' Intrahepatic Cholestasis of Pregnancy.
abstract: Little is known about the effects of mother's intrahepatic cholestasis of pregnancy (ICP) on the health of sons born to these mothers. The purpose of the present study was to explore the health of sons born to mothers with ICP. The study design was a retrospective study of ICP mothers' sons. In the region of Tampere University Hospital in Finland, 365 sons of mothers with ICP during 1969 to 1988 and 617 sons of mothers without ICP were sent a questionnaire in 2010. The response rates were 37.8% (n = 138) and 36.6% (n = 226), respectively. Only minor differences were reported between the two groups. Self-evaluated health was similar. There were no significant differences between the groups regarding symptoms and complaints, diagnosed diseases, mental health, and use of medicines. Cough was 10.8 percentage points less common among ICP mothers' sons than among controls (p = .034). Urticaria was more common among ICP mothers' sons, the difference in percentage points being 2.2 (p = .026). In general, a mother's ICP does not affect her son's health.
authors.affiliation: University of Tampere, Tampere, Finland Ikaalinen Health Center, Ikaalinen, Finland suvi.hamalainen@uta.fi.
authors.forename: Suvi-Tuulia
authors.initials: ST
authors.lastname: Hämäläinen
authors.affiliation: University of Tampere, Tampere, Finland.
authors.forename: Kaisa
authors.initials: K
authors.lastname: Turunen
authors.affiliation: University of Tampere, Tampere, Finland Pirkanmaa Hospital District, Tampere, Finland.
authors.forename: Elise
authors.initials: E
authors.lastname: Kosunen
authors.affiliation: University of Tampere, Tampere, Finland.
authors.forename: Kari J
authors.initials: KJ
authors.lastname: Mattila
authors.affiliation: University of Tampere, Tampere, Finland.
authors.forename: Markku
authors.initials: M
authors.lastname: Sumanen
mesh_terms: D000328:Adult; D001660:Biliary Tract Diseases / Q000453:epidemiology; D002780:Cholestasis, Intrahepatic / Q000150:complications*; D005260:Female; D005387:Finland; D006304:Health Status; D006801:Humans; D008297:Male; D054526:Men's Health; D011247:Pregnancy; D011248:Pregnancy Complications; D012189:Retrospective Studies; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013997:Time Factors; D055815:Young Adult
keywords: cough; intrahepatic cholestasis of pregnancy; men’s health; smoking; urticaria