title: Enhanced sensitive love wave surface acoustic wave sensor designed for immunoassay formats.
abstract: We report a Love wave surface acoustic wave (LW-SAW) immunosensor designed for the detection of high molecular weight targets in liquid samples, amenable also for low molecular targets in surface competition assays. We implemented a label-free interaction protocol similar to other surface plasmon resonance bioassays having the advantage of requiring reduced time analysis. The fabricated LW-SAW sensor supports the detection of the target in the nanomolar range, and can be ultimately incorporated in portable devices, suitable for point-of-care testing (POCT) applications.
authors.affiliation: LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania. elenamihaela.puiu@g.unibuc.ro.
authors.forename: Mihaela
authors.initials: M
authors.lastname: Puiu
authors.affiliation: LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania. amgurban@yahoo.com.
authors.forename: Ana-Maria
authors.initials: AM
authors.lastname: Gurban
authors.affiliation: LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania. lucian.rotariu@g.unibuc.ro.|Department of Analytical Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania. lucian.rotariu@g.unibuc.ro.
authors.forename: Lucian
authors.initials: L
authors.lastname: Rotariu
authors.affiliation: National Institute for Laser, Plasma and Radiation Physics, 409 Atomistilor Blvd., RO-077125 Magurele, Romania. simonabrajnicov@yahoo.com.
authors.forename: Simona
authors.initials: S
authors.lastname: Brajnicov
authors.affiliation: National Institute for Laser, Plasma and Radiation Physics, 409 Atomistilor Blvd., RO-077125 Magurele, Romania. cristian.viespe@inflpr.ro.
authors.forename: Cristian
authors.initials: C
authors.lastname: Viespe
authors.affiliation: LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania. camelia.bala@g.unibuc.ro.|Department of Analytical Chemistry, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania. camelia.bala@g.unibuc.ro.
authors.forename: Camelia
authors.initials: C
authors.lastname: Bala
mesh_terms: D007118:Immunoassay / Q000379:methods*; D013016:Sound