title: Prevalence, knowledge, and treatment of transient ischemic attacks in China.
abstract: OBJECTIVE
  To investigate the prevalence, knowledge, and treatment of TIA in a Chinese adult population.
  
  
  METHODS
  We conducted a complex, multistage, probability sampling-designed, cross-sectional, nationwide survey of 98,658 Chinese adults in 2010. Possible TIA cases were first identified by symptoms recall or self-reported history of TIA through face-to-face interviews, and the final diagnosis was then made by expert neurologists through phone interviews or record review.
  
  
  RESULTS
  The age-standardized prevalence of TIA was 2.27%. Clinically, only 16.0% of the participants were diagnosed before the study. The prevalence of TIA was higher in women and in patients who were older, had less education, were current smokers, lived in rural or undeveloped areas, and had a history of stroke, hypertension, myocardial infarction, dyslipidemia, or diabetes. Based on the survey responses, approximately 3.08% of Chinese adults had knowledge of TIA. Among patients with TIA, only 5.02% received treatment and 4.07% received guideline-recommended therapy.
  
  
  CONCLUSIONS
  TIA is prevalent and an estimated 23.9 million people in China may have experienced a TIA. Public knowledge on TIA is very limited. TIA appears to be largely undiagnosed and untreated in China. There is an urgent need to develop strategies to improve the identification and appropriate management of TIA.
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China. yongjunwang1962@gmail.com yilong528@gmail.com.
authors.forename: Yilong
authors.initials: Y
authors.lastname: Wang
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Xingquan
authors.initials: X
authors.lastname: Zhao
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Li
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Limin
authors.initials: L
authors.lastname: Wang
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: S Claiborne
authors.initials: SC
authors.lastname: Johnston
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Liu
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Ka Sing Lawrence
authors.initials: KS
authors.lastname: Wong
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Chunxue
authors.initials: C
authors.lastname: Wang
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Yuesong
authors.initials: Y
authors.lastname: Pan
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Jing
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Xu
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Meng
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Mei
authors.initials: M
authors.lastname: Zhang
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Yichong
authors.initials: Y
authors.lastname: Li
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.
authors.forename: Wenhua
authors.initials: W
authors.lastname: Zhao
authors.affiliation: From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China. yongjunwang1962@gmail.com yilong528@gmail.com.
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D002546:Ischemic Attack, Transient / Q000453:epidemiology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D055815:Young Adult