title: [Serum 25-Hydroxyvitamin D3 Level in Peripheral Blood of Patients with Non-Hodgkin's Lymphoma and Its Clinical Significance].
abstract: OBJECTIVE
  To explore the correlation between the level of serum 25-hydroxyvi-tamin D3 and the development and prognosis of NHL in order to provide the theoretical basic for the diagnosis, treatment and prognosis of NHL.
  
  
  METHODS
  The serum 25-hydroxyvitamin D's level of 84 NHL patients and 60 healthy persons was detected by using enzyme-linked immunsorbent assay.
  
  
  RESULTS
  The level of serum 25-hydroxyvitamin D3 in NHL group was significantly lower than that in normal control group and the difference between NHL patients and normal controls was statistically significant. The stage and cell source of NHL patients showed little effect on the level of 25-hydroxyvitamin D3. There were significant differences of the level of 25-hydroxyvitamin D3 in different group and sites of origin as well as in presence or absence of bone marrow infiltration.
  
  
  CONCLUSIONS
  The level of 25-hydroxyvitamin D3 can be considered as tumor burden index of NHL and can be used to evaluate the prognosis of NHL.
authors.affiliation: Department of Hematology, General Hospital of Chinese PLA Shenyang Military Command, Shenyang 110016, Liaoning Province, China.
authors.forename: Cong-Cong
authors.initials: CC
authors.lastname: Ma
authors.affiliation: Department of Hematology, General Hospital of Chinese PLA Shenyang Military Command, Shenyang 110016, Liaoning Province, China. E-mail: Liuyq12341234@163.com.
authors.forename: Yan-Qin
authors.initials: YQ
authors.lastname: Liu
mesh_terms: D002112:Calcifediol; D006801:Humans; D008228:Lymphoma, Non-Hodgkin; D011379:Prognosis
chemical_list: D002112:Calcifediol