title: Nocardia asteroides sinusitis in a pediatric patient: Case report with 20 year follow-up and review of the literature.
abstract: Nocardia Asteroides infection in a non-immunocompromised pediatric patient is extremely rare. We present a case of ethmoid sinusitis and orbital subperiosteal abscess caused by N. asteroides with a 20 year follow up and a review of the literature. N. asteroides was grown from intraoperative cultures for mycobacteria following surgical incision and drainage of the abscess. Postoperatively, the patient received a seven month course of trimethoprim-sulfamethozaxole and had no subsequent sequelae. Nocardia infections are common in immunocompromised patients. We present what we believe to be the first case of pediatric Nocardia sinusitis with 20-year follow up.
authors.affiliation: Division of Pediatric Otolaryngology, Head & Neck Surgery, BC Children's Hospital, University of British Columbia, K2-184, ACB, 4480 Oak Street, Vancouver, BC, Canada V6H 3V4.
authors.forename: Brendan
authors.initials: B
authors.lastname: Sorichetti
authors.affiliation: Division of Otolaryngology, Head & Neck Surgery, University of British Columbia, Vancouver, BC, Canada; B.C. Rotary Hearing and Balance Centre, Vancouver, BC, Canada.
authors.forename: Brian D
authors.initials: BD
authors.lastname: Westerberg
authors.affiliation: Sidra Medical and Research Center, Doha, Qatar.
authors.forename: Rusung
authors.initials: R
authors.lastname: Tan
authors.affiliation: Division of Pediatric Otolaryngology, Head & Neck Surgery, BC Children's Hospital, University of British Columbia, K2-184, ACB, 4480 Oak Street, Vancouver, BC, Canada V6H 3V4. Electronic address: fkozak@cw.bc.ca.
authors.forename: Frederick K
authors.initials: FK
authors.lastname: Kozak
mesh_terms: D000038:Abscess / Q000382:microbiology / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D004322:Drainage; D015521:Ethmoid Sinusitis / Q000188:drug therapy / Q000382:microbiology*; D005500:Follow-Up Studies; D006801:Humans; D007121:Immunocompetence; D008297:Male; D009617:Nocardia Infections / Q000175:diagnosis*; D009616:Nocardia asteroides; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
keywords: Nocardia asteroides; Nocardiosis; Non-immunocompromised; Pediatric; Sinusitis