title: Database integration of protocol-specific neurological imaging datasets.
abstract: For many years now, Magnetic Resonance Innovations (MR Innovations), a magnetic resonance imaging (MRI) software development, technology, and research company, has been aggregating a multitude of MRI data from different scanning sites through its collaborations and research contracts. The majority of the data has adhered to neuroimaging protocols developed by our group which has helped ensure its quality and consistency. The protocols involved include the study of: traumatic brain injury, extracranial venous imaging for multiple sclerosis and Parkinson's disease, and stroke. The database has proven invaluable in helping to establish disease biomarkers, validate findings across multiple data sets, develop and refine signal processing algorithms, and establish both public and private research collaborations. Myriad Masters and PhD dissertations have been possible thanks to the availability of this database. As an example of a project that cuts across diseases, we have used the data and specialized software to develop new guidelines for detecting cerebral microbleeds. Ultimately, the database has been vital in our ability to provide tools and information for researchers and radiologists in diagnosing their patients, and we encourage collaborations and welcome sharing of similar data in this database.
authors.affiliation: Magnetic Resonance Innovations, Inc., Detroit, MI, USA; The MRI Institute for Biomedical Research, Detroit, MI, USA.
authors.forename: Emil E
authors.initials: EE
authors.lastname: Pacurar
authors.affiliation: Magnetic Resonance Innovations, Inc., Detroit, MI, USA; The MRI Institute for Biomedical Research, Detroit, MI, USA. Electronic address: sethisea@gmail.com.
authors.forename: Sean K
authors.initials: SK
authors.lastname: Sethi
authors.affiliation: Magnetic Resonance Innovations, Inc., Detroit, MI, USA; Department of Radiology, Wayne State University, Detroit, MI, USA.
authors.forename: Charbel
authors.initials: C
authors.lastname: Habib
authors.affiliation: Magnetic Resonance Innovations, Inc., Detroit, MI, USA.
authors.forename: Marius O
authors.initials: MO
authors.lastname: Laze
authors.affiliation: Magnetic Resonance Innovations, Inc., Detroit, MI, USA; The MRI Institute for Biomedical Research, Detroit, MI, USA; Department of Radiology, Wayne State University, Detroit, MI, USA.
authors.forename: Rachel
authors.initials: R
authors.lastname: Martis-Laze
authors.affiliation: Magnetic Resonance Innovations, Inc., Detroit, MI, USA; The MRI Institute for Biomedical Research, Detroit, MI, USA; Department of Radiology, Wayne State University, Detroit, MI, USA.
authors.forename: E Mark
authors.initials: EM
authors.lastname: Haacke
mesh_terms: D000465:Algorithms; D015415:Biomarkers; D003628:Database Management Systems; D016208:Databases, Factual; D006801:Humans; D033181:Information Dissemination; D008279:Magnetic Resonance Imaging; D009422:Nervous System Diseases / Q000175:diagnosis / Q000473:pathology; D059906:Neuroimaging; D012984:Software; D014584:User-Computer Interface
chemical_list: D015415:Biomarkers