title: [Allergic factors affect on severity of chronic rhinosinusitis and postoperative outcomes].
abstract: OBJECTIVE
  To investigate whether the allergic factors impact the severity of chronic rhinosinusitis or not, further more, to explore the relationship between allergic rhinitis and chronic rhinosinusitis.
  
  
  METHODS
  A retrospective review was done on 103 patients. All of these patients were under functional intranasal endoscopic sinus surgery after expectant treatment is ineffective. We devided the patients into different groups according to the result of skin prick and specific IgE and if there is difference in VAS score, Lund and Kennedy endoscopic score, Lund-Mackay CT score between the groups. We also analysed the symptoms in different chronic rhinosinusitis patients allerged to variant kinds of allergen. The SPSS 17.0 software was used to analyze the data. Statistical analysis was performed by t-test, rank order test or χ2 test.
  
  
  RESULTS
  The duration of the disease, VAS score of nasal blockage, score of Lund-Mackay CT and Lund and Kennedy endoscopic before the operation were in no statistical sense after when compared with the two groups of patients with chronic rhiriosinusitis who grouped according the result of skin prick and specific IgE. The VAS score of facial pressure and loss of smell was higher in patients with chronic rhinosinusitis which the skin prick and specific IgE were positive. The VAS score of nasal discharge was higher in patients with chronic rhinosinusitis who got negative skin prick and specific IgE result. The symptoms of chronic rhinosinusitis improved with operation no matter the group of skin prick and specific IgE positive or negative and VAS score of nasal blockage improved significantly in negative group. The symptoms of sneezing, rhinorrhoea and rhinocnesmus improved after operation among the chronic rhinosinusitis patients with skin prick and specific IgE. The number of cockroach allergy is larger among the patients with chronic rhinosinusitis without polyps than the one among the patients with chronic rhinosinusitis with polyps.
  
  
  CONCLUSIONS
  Allergic factor didn't impact much the severity of chronic rhinosinusitis patients who were failed in expectant treatment, besidesthe postoperative outcomes showed that only influence the severity of nasal discharge, facial pressure and loss of smell. Different kinds of allergen were found between the patients of chronic rhinosinusitis with or without polyps. No significantly functional endoscopic sinusitis sugrery outcome were related to the allergic factor. But the allergic factor may interfere the remission of nasal discharge after surgery.
authors.forename: Qian
authors.initials: Q
authors.lastname: Xiu
authors.forename: Cuida
authors.initials: C
authors.lastname: Meng
authors.forename: Lin
authors.initials: L
authors.lastname: Li
authors.forename: Dongdong
authors.initials: D
authors.lastname: Zhu
authors.forename: Zhen
authors.initials: Z
authors.lastname: Dong
mesh_terms: D000281:Administration, Intranasal; D000485:Allergens; D002908:Chronic Disease; D004724:Endoscopy; D006801:Humans; D015508:Nasal Obstruction; D009298:Nasal Polyps / Q000601:surgery; D011127:Polyps; D011184:Postoperative Period; D012189:Retrospective Studies; D012220:Rhinitis / Q000276:immunology / Q000601:surgery*; D065631:Rhinitis, Allergic / Q000601:surgery*; D012852:Sinusitis
chemical_list: D000485:Allergens