title: Cognitive rehabilitation in multiple sclerosis: a randomized controlled trial.
abstract: BACKGROUND
  The evidence base in cognitive rehabilitation in multiple sclerosis (MS) is still sparse.
  
  
  OBJECTIVE
  The aim of the study was to investigate the effects of cognitive rehabilitation on cognitive and executive coping, psychological well-being and psychological aspects of health-related quality of life (HRQoL) in patients with MS.
  
  
  METHODS
  One hundred and twenty patients with cognitive complaints, taking part in a 4-week multidisciplinary rehabilitation, were randomized to an intervention group (n = 60) and a control group (n = 60). Both groups underwent neuropsychological assessment with subsequent feedback and took part in general multidisciplinary MS rehabilitation. Additionally, the intervention group participated in cognitive group sessions as well as individual sessions. The main focus was to formulate Goal Attainment Scaling goals for coping with cognitive challenges. For 3 months past rehabilitation, the intervention group received biweekly telephone follow-up, focusing on goal attainment.
  
  
  RESULTS
  Executive functioning improved significantly from baseline to four and 7 months in both groups. Improvements in psychological well-being and psychological aspects of HRQoL occurred only in the intervention group.
  
  
  CONCLUSIONS
  Multicomponent cognitive rehabilitation administered within the context of multidisciplinary rehabilitation can improve psychological well-being and psychological aspects of HRQoL.
authors.affiliation: Multiple Sclerosis Centre Hakadal, Oslo, Norway.|Department of Neurology, Akershus University Hospital, Oslo, Norway.
authors.forename: K T
authors.initials: KT
authors.lastname: Hanssen
authors.affiliation: Multiple Sclerosis Centre Hakadal, Oslo, Norway.
authors.forename: A G
authors.initials: AG
authors.lastname: Beiske
authors.affiliation: Clinical Neuroscience Research Group, Department of Psychology, University of Oslo, Oslo, Norway.
authors.forename: N I
authors.initials: NI
authors.lastname: Landrø
authors.affiliation: Institute of Health and Society, University of Oslo, Oslo, Norway.
authors.forename: D
authors.initials: D
authors.lastname: Hofoss
authors.affiliation: Department of Neurology, Akershus University Hospital, Oslo, Norway.|Clinical Neuroscience Research Group, Department of Psychology, University of Oslo, Oslo, Norway.|Department for Complex Epilepsy, Oslo University Hospital, Oslo, Norway.
authors.forename: E
authors.initials: E
authors.lastname: Hessen
mesh_terms: D000223:Adaptation, Psychological / Q000502:physiology; D000328:Adult; D000368:Aged; D003071:Cognition / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis / Q000523:psychology* / Q000534:rehabilitation*; D056344:Executive Function / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000523:psychology* / Q000534:rehabilitation*; D009483:Neuropsychological Tests; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology*
keywords: multiple sclerosis; neuropsychology; quality of life; rehabilitation