title: The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso.
abstract: OBJECTIVE
  To evaluate the epidemiological evolution of patients with HIV (PtHIV), between 2002 and 2012, in a day-hospital that became an HIV reference centre for south-west Burkina Faso.
  
  
  METHODS
  This was a retrospective study of PtHIV followed in the Bobo Dioulasso university hospital since 2002. The study was based on clinical data recorded using ESOPE software and analysed using Excel and SAS.
  
  
  RESULTS
  A total of 7320 patients have been treated at the centre since 2002; the active file of patients increased from 147 in 2002 to 3684 patients in 2012. Mean age was stable at 38.4 years and the majority were female (71%). The delay to initiation of antiretroviral (ARV) treatment after HIV diagnosis decreased from 12.9 months in 2002 to 7.2 months in 2012. The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005. Voluntary anonymous screening and/or an evocative clinical picture were the main reasons for HIV diagnosis, usually at a late stage (41.1% at WHO stage 3). Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1st line drugs). However, there was also a slight increase in the rate of therapeutic failures and the percentage of patients who progressed to 2nd or 3rd line-ARVs.
  
  
  CONCLUSIONS
  Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso).
authors.affiliation: Service des Maladies Infectieuses et Tropicales, Hôpital Tenon, Paris, France.
authors.forename: Julie
authors.initials: J
authors.lastname: Chas
authors.affiliation: Hôpital de Jour, CHU Sourô Sanou, Bobo Dioulasso, Burkina Faso.
authors.forename: Arsène
authors.initials: A
authors.lastname: Hema
authors.affiliation: Service des Maladies Infectieuses et Tropicales, Hôpital Tenon, Paris, France.
authors.forename: Laurence
authors.initials: L
authors.lastname: Slama
authors.affiliation: Hôpital de Jour, CHU Sourô Sanou, Bobo Dioulasso, Burkina Faso.
authors.forename: Nongondo Firmin
authors.initials: NF
authors.lastname: Kabore
authors.affiliation: AP-HP, Service de Maladies Infectieuses et Tropicales et IAME, Hôpital Bichat-Claude Bernard, UMR 1137, INSERM, Univ Paris Diderot, Sorbonne Paris Cité, F-75018 Paris, France.
authors.forename: François-Xavier
authors.initials: FX
authors.lastname: Lescure
authors.affiliation: Centre 190, Paris, France.
authors.forename: Camille
authors.initials: C
authors.lastname: Fontaine
authors.affiliation: Service des Maladies Infectieuses et Tropicales, Hôpital Tenon, Paris, France; UPMC, Paris, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Pialoux
authors.affiliation: Hôpital de Jour, CHU Sourô Sanou, Bobo Dioulasso, Burkina Faso.
authors.forename: Adrien
authors.initials: A
authors.lastname: Sawadogo
mesh_terms: D000293:Adolescent; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D002050:Burkina Faso / Q000453:epidemiology; D003631:Day Care, Medical; D019468:Disease Management; D004359:Drug Therapy, Combination; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000401:mortality; D006297:Health Services Accessibility; D006785:Hospitals, University; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents