title: On resin synthesis and cross-linking of collagen peptides containing the advanced glycation end-product pyrraline via Maillard condensation.
abstract: Glycation and its products cause a host of pathological conditions but their exact roles are yet to be determined. Pyrraline, a key product of glycation, and a novel pyrraline-derived cross-link have been incorporated into collagenous peptides via Maillard condensations performed on resin-bound peptide sequences.
authors.affiliation: School of Chemical Sciences, The University of Auckland, 23 Symonds St, Auckland, New Zealand. m.brimble@auckland.ac.nz.
authors.forename: Meder
authors.initials: M
authors.lastname: Kamalov
authors.forename: Paul W R
authors.initials: PW
authors.lastname: Harris
authors.forename: James M
authors.initials: JM
authors.lastname: Wood
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Brimble
mesh_terms: D003094:Collagen / Q000737:chemistry*; D017127:Glycation End Products, Advanced / Q000737:chemistry*; D009646:Norleucine / Q000031:analogs & derivatives* / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D011137:Polystyrenes / Q000737:chemistry; D011758:Pyrroles / Q000737:chemistry*
chemical_list: D017127:Glycation End Products, Advanced; D010455:Peptides; D011137:Polystyrenes; D011758:Pyrroles; C101297:Tentagel resin; C059571:2-formyl-5-(hydroxymethyl)pyrrole-1-norleucine; D009646:Norleucine; D003094:Collagen