title: Langerhans cell histiocytosis in monozygotic twins with central diabetes insipidus and hypophyseal masses.
abstract: Langerhans cell histiocytosis (LCH) is a systemic disease mainly affecting children and young adults. It can manifest as single system disorder or multi-system involvement. When the central nervous system is involved, the hypothalamic-pituitary axis is the most common location affected. Herein we report a rare case of Langerhans cell histiocytosis in monozygotic twins both with central diabetes and hypophyseal masses. This is the first report about LCH in monozygotic twins with hypophyseal lesions.
authors.affiliation: Department of Neurosurgery, China Medical University and Hospital, Taichung, Taiwan, R.O.C.
authors.forename: Sung-Tai
authors.initials: ST
authors.lastname: Wei
authors.affiliation: Department of Neurosurgery, China Medical University and Hospital, Taichung, Taiwan, R.O.C.
authors.forename: Der-Cherng
authors.initials: DC
authors.lastname: Chen
authors.affiliation: Department of Neurosurgery, China Medical University and Hospital, Taichung, Taiwan, R.O.C ; Graduate Institute of Immunology, China Medical University, Taichung, Taiwan, R.O.C.
authors.forename: Der-Yang
authors.initials: DY
authors.lastname: Cho
authors.affiliation: Department of Neurosurgery, China Medical University and Hospital, Taichung, Taiwan, R.O.C.
authors.forename: Hung-Lin
authors.initials: HL
authors.lastname: Lin
keywords: Diabetes insipidus; infundibulum; langerhans cell histiocytosis; twins