title: Locking plate placement with unicortical screw fixation adjunctive to intramedullary rodding in long bones of patients with osteogenesis imperfecta.
abstract: BACKGROUND
  Intramedullary rodding has been the mainstay of long-bone stabilization in osteogenesis imperfecta. However, in some cases, intramedullary rodding cannot provide adequate fixation because of a lack of rotational control and thin diameter of long bones. We have applied adjunctive unicortical locking plate fixation in selected cases of osteogenesis imperfecta to address these biomechanical issues.
  
  
  METHODS
  Thirty-seven bone segments of twenty-four patients with osteogenesis imperfecta (ten type III, nine type IV, three type I, and two type V), in which unicortical locking plate fixation was applied adjunctive to intramedullary rodding and was later removed after union had been achieved, were the study subjects. The mean patient age at the time of surgery was 15.5 years (range, 6.2 to 39.8 years). Medical records and follow-up radiographs were reviewed to evaluate healing, complications, and the fates of screw holes after plate removal.
  
  
  RESULTS
  All fractures or osteotomies healed completely. Locking plates were removed postoperatively at a mean time (and standard deviation) of 1.8 ± 0.9 years (range, 0.3 to 3.8 years). In seven of the thirty-seven cases, fractures through the screw hole occurred; all of these were treated conservatively. In eighteen of nineteen cases that were followed for more than a year after plate removal without screw hole-related complication, screw holes healed and were no longer visualized by radiography.
  
  
  CONCLUSIONS
  Unicortical locking plate fixation effectively supplements intramedullary rod fixation in selected cases of osteogenesis imperfecta.
  
  
  METHODS
  Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
authors.affiliation: Division of Pediatric Orthopaedics, Seoul National University Children's Hospital, 101 Daehak-ro Jongno-gu, Seoul 110-744, Republic of Korea. E-mail address for T.-J. Cho: tjcho@snu.ac.kr.
authors.forename: Tae-Joon
authors.initials: TJ
authors.lastname: Cho
authors.affiliation: Department of Orthopaedic Surgery, Kangwon National University Hospital, 156 Baengnyeong-ro, Chuncheon, Gangwon-Do 200-722, Republic of Korea.
authors.forename: Kang
authors.initials: K
authors.lastname: Lee
authors.affiliation: Department of Orthopaedic Surgery, Kyungpook National University Hospital, 130 Dongdeok-ro, Jung-gu, Daegu 700-721, Republic of Korea.
authors.forename: Chang-Wug
authors.initials: CW
authors.lastname: Oh
authors.affiliation: Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, 82 Gumi-ro 173 Beon-gil, Seongnam, Kyunggi 463-707, Republic of Korea.
authors.forename: Moon Seok
authors.initials: MS
authors.lastname: Park
authors.affiliation: Division of Pediatric Orthopaedics, Seoul National University Children's Hospital, 101 Daehak-ro Jongno-gu, Seoul 110-744, Republic of Korea. E-mail address for T.-J. Cho: tjcho@snu.ac.kr.
authors.forename: Won Joon
authors.initials: WJ
authors.lastname: Yoo
authors.affiliation: Division of Pediatric Orthopaedics, Seoul National University Children's Hospital, 101 Daehak-ro Jongno-gu, Seoul 110-744, Republic of Korea. E-mail address for T.-J. Cho: tjcho@snu.ac.kr.
authors.forename: In Ho
authors.initials: IH
authors.lastname: Choi
mesh_terms: D000293:Adolescent; D000328:Adult; D001863:Bone Screws; D002648:Child; D005500:Follow-Up Studies; D005592:Fracture Fixation / Q000379:methods; D050723:Fractures, Bone / Q000601:surgery; D006801:Humans; D010013:Osteogenesis Imperfecta / Q000601:surgery*; D011183:Postoperative Complications; D014945:Wound Healing