title: [DRESS syndrome or reaction to drugs with eosinophilia and systemic symptoms associated to anti-tuberculosis drugs].
abstract: Tuberculosis has increased all over the world. This paper reports the case of a male patient with tuberculous meningitis, spinal tuberculosis (Pott's disease) and severe adverse reactions to antituberculosis drugs. He had skin rash, hepatitis, eosinophilia and fever; all these signs make the diagnosis of DRESS syndrome. This syndrome is caused by a severe hypersensitivity reaction to different drugs. It is usually caused by anticonvulsants, sulfonamides and some antiviral drugs, among other drugs. Anti-tuberculosis drugs can also cause this potentially fatal syndrome. The importance of surveillance for early detection and treatment of adverse drug reactions is emphasized.
authors.affiliation: Servicio de Neumología, Hospital Regional Vicente Corral Moscoso, Cuenca, Ecuador. luisrenecordova@hotmail.com.
authors.forename: Luis René
authors.initials: LR
authors.lastname: Fernández de Córdova-Rodríguez1
authors.forename: Karol Andrea
authors.initials: KA
authors.lastname: Guzmán-Guillén
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Fernández de Córdova-Aguirre
keywords: Adverse drug reactions; DRESS; Eosinophilia; Tuberculosis