title: Cardiovascular effects of volatile induction and maintenance of anesthesia (VIMA) and total intravenous anesthesia (TIVA) for laryngeal mask airway (LMA) anesthesia: a comparison study.
abstract: OBJECTIVE
  To compare changes of heart rate and blood pressure in patients that underwent LMA anesthesia with VIMA or TIVA technique.
  
  
  METHODS
  A hundred healthy patients, age 16 to 60 years were enrolled. They were randomized into two groups. Patients in group V (VIMA) were induced with 8% sevoflurane until loss of eyelash reflexes then controlled ventilation for five minutes before LMA insertion. Group T (TIVA) patients were given propofol to reach the affected site concentration of eight mcg/mlfor the LMA insertion. Bloodpressure and heart rate were recorded before induction, immediately before and after LMA insertion then every two minutes until surgical incision.
  
  
  RESULTS
  Decreased SBP from baseline in group T was significantly more than group V in each period of time (D1-D7). DBP in group T decreased more than group V significantly only at eight and ten minutes after LMA insertion. The incidence of decreasing SBP > 20% from baseline was more significant in group T than group V. No significant difference of changed HR was found. Coughing during LMA insertion occurred in eight patients (16%) in group T and in three patients (6%) in group V (p = 0.11).
  
  
  CONCLUSIONS
  Induction with propofol by effective site concentration of eight mcg/ml significantly decreased SBP more than with 8% sevoflurane. Both techniques provided smooth LMA insertion without serious complication.
authors.forename: Wariya
authors.initials: W
authors.lastname: Sukhupragarn
authors.forename: Prangmalee
authors.initials: P
authors.lastname: Leurcharusmee
authors.forename: Thitipan
authors.initials: T
authors.lastname: Sotthisopha
mesh_terms: D000293:Adolescent; D000328:Adult; D000758:Anesthesia / Q000379:methods; D000771:Anesthesia, Intravenous / Q000009:adverse effects / Q000379:methods*; D001794:Blood Pressure / Q000187:drug effects; D003371:Cough / Q000139:chemically induced / Q000453:epidemiology; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D015994:Incidence; D017214:Laryngeal Masks; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage* / Q000009:adverse effects; D008875:Middle Aged; D015742:Propofol / Q000008:administration & dosage* / Q000009:adverse effects; D000077149:Sevoflurane; D055815:Young Adult
chemical_list: D008738:Methyl Ethers; D000077149:Sevoflurane; D015742:Propofol