title: Tiered approach to metabolite quantification: regional practices reviewed by Japan Bioanalysis Forum discussion group.
authors.affiliation: Pharmacokinetics Team, Pharmaceutical Research Laboratories, Nippon Kayaku Co., Ltd, 3-31-12 Shimo, Kita-ku, Tokyo 115-8588 Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Niwa
authors.forename: Takahide
authors.initials: T
authors.lastname: Uchimura
authors.forename: Nozomu
authors.initials: N
authors.lastname: Koseki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Satsukawa
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Mayumi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Yasuda
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yokoi
mesh_terms: D002986:Clinical Trials as Topic; D055808:Drug Discovery; D006801:Humans; D007564:Japan; D055432:Metabolomics; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000378:metabolism*
chemical_list: D004364:Pharmaceutical Preparations
keywords: drug development; drug discovery; drug metabolism; metabolite; tiered approach; toxicokinetics