title: Ascher's syndrome: A rare case report.
abstract: An 18-year-old Indian girl with upper lip deformity presented with on and off painless swelling of her both upper eyelids for 3 years. Clinical evaluation revealed bilateral blepharochalasis, narrowing of horizontal palpebral fissure, decreased outer intercanthal distance, iris coloboma, cleft soft palate, bifid uvula, sensorineural deafness and double upper lip. Clinical examination of the thyroid, thyroid hormone assay and ultrasonography revealed normal thyroid gland structure and function. Ascher's syndrome was diagnosed. To our knowledge, this is the first reported case of Ascher's syndrome associated with iris coloboma, heterochromia iridum, and narrowing of horizontal palpebral fissure and decreased outer intercanthal distance secondary to lengthening of lateral canthal ligament.
authors.affiliation: Department of Ophthalmology, Shyam Shah Medical College, Rewa, Madhya Pradesh, India.
authors.forename: Shivcharan Lal
authors.initials: SL
authors.lastname: Chandravanshi
authors.forename: Vinay
authors.initials: V
authors.lastname: Mishra
mesh_terms: D000293:Adolescent; D019465:Craniofacial Abnormalities / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005143:Eyelids / Q000002:abnormalities*; D005260:Female; D006042:Goiter / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D008046:Lip / Q000002:abnormalities*; D035583:Rare Diseases