title: Childhood sleep disturbance and risk of psychotic experiences at 18: UK birth cohort.
abstract: BACKGROUND
  Sleep disturbances are commonly reported in the psychosis prodrome, but rarely explored in relation to psychotic experiences.
  
  
  OBJECTIVE
  To investigate the relationship between specific parasomnias (nightmares, night terrors and sleepwalking) in childhood and later adolescent psychotic experiences.
  
  
  METHODS
  The sample comprised 4720 individuals from a UK birth cohort. Mothers reported on children's experience of regular nightmares at several time points between 2 and 9 years. Experience of nightmares, night terrors and sleepwalking was assessed using a semi-structured interview at age 12. Psychotic experiences were assessed at ages 12 and 18 using a semi-structured clinical interview.
  
  
  RESULTS
  There was a significant association between the presence of nightmares at 12 and psychotic experiences at 18 when adjusted for possible confounders and psychotic experiences at 12 (OR = 1.62, 95% CI 1.19-2.20). The odds ratios were larger for those who reported persistent psychotic experiences.
  
  
  CONCLUSIONS
  The presence of nightmares might be an early risk indicator for psychosis.
authors.affiliation: A. Thompson, MD, FRCPsych, Division of Mental Health and Wellbeing, University of Warwick, Coventry; S. T. Lereya, PhD, Department of Psychology, University of Warwick, Coventry; G. Lewis, PhD, MRCPsych, Division of Psychiatry, University College London, London; S. Zammit, PhD, MRCPsych, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff and Centre for Academic Mental Health, School of Social and Community Medicine, University of Bristol, Bristol; H. L. Fisher, PhD, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London; D. Wolke, PhD, Division of Mental Health and Wellbeing and Department of Psychology, University of Warwick, Coventry, UK Andrew.d.thompson@warwick.ac.uk.
authors.forename: A
authors.initials: A
authors.lastname: Thompson
authors.affiliation: A. Thompson, MD, FRCPsych, Division of Mental Health and Wellbeing, University of Warwick, Coventry; S. T. Lereya, PhD, Department of Psychology, University of Warwick, Coventry; G. Lewis, PhD, MRCPsych, Division of Psychiatry, University College London, London; S. Zammit, PhD, MRCPsych, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff and Centre for Academic Mental Health, School of Social and Community Medicine, University of Bristol, Bristol; H. L. Fisher, PhD, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London; D. Wolke, PhD, Division of Mental Health and Wellbeing and Department of Psychology, University of Warwick, Coventry, UK.
authors.forename: S T
authors.initials: ST
authors.lastname: Lereya
authors.affiliation: A. Thompson, MD, FRCPsych, Division of Mental Health and Wellbeing, University of Warwick, Coventry; S. T. Lereya, PhD, Department of Psychology, University of Warwick, Coventry; G. Lewis, PhD, MRCPsych, Division of Psychiatry, University College London, London; S. Zammit, PhD, MRCPsych, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff and Centre for Academic Mental Health, School of Social and Community Medicine, University of Bristol, Bristol; H. L. Fisher, PhD, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London; D. Wolke, PhD, Division of Mental Health and Wellbeing and Department of Psychology, University of Warwick, Coventry, UK.
authors.forename: G
authors.initials: G
authors.lastname: Lewis
authors.affiliation: A. Thompson, MD, FRCPsych, Division of Mental Health and Wellbeing, University of Warwick, Coventry; S. T. Lereya, PhD, Department of Psychology, University of Warwick, Coventry; G. Lewis, PhD, MRCPsych, Division of Psychiatry, University College London, London; S. Zammit, PhD, MRCPsych, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff and Centre for Academic Mental Health, School of Social and Community Medicine, University of Bristol, Bristol; H. L. Fisher, PhD, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London; D. Wolke, PhD, Division of Mental Health and Wellbeing and Department of Psychology, University of Warwick, Coventry, UK.
authors.forename: S
authors.initials: S
authors.lastname: Zammit
authors.affiliation: A. Thompson, MD, FRCPsych, Division of Mental Health and Wellbeing, University of Warwick, Coventry; S. T. Lereya, PhD, Department of Psychology, University of Warwick, Coventry; G. Lewis, PhD, MRCPsych, Division of Psychiatry, University College London, London; S. Zammit, PhD, MRCPsych, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff and Centre for Academic Mental Health, School of Social and Community Medicine, University of Bristol, Bristol; H. L. Fisher, PhD, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London; D. Wolke, PhD, Division of Mental Health and Wellbeing and Department of Psychology, University of Warwick, Coventry, UK.
authors.forename: H L
authors.initials: HL
authors.lastname: Fisher
authors.affiliation: A. Thompson, MD, FRCPsych, Division of Mental Health and Wellbeing, University of Warwick, Coventry; S. T. Lereya, PhD, Department of Psychology, University of Warwick, Coventry; G. Lewis, PhD, MRCPsych, Division of Psychiatry, University College London, London; S. Zammit, PhD, MRCPsych, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff and Centre for Academic Mental Health, School of Social and Community Medicine, University of Bristol, Bristol; H. L. Fisher, PhD, MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London; D. Wolke, PhD, Division of Mental Health and Wellbeing and Department of Psychology, University of Warwick, Coventry, UK.
authors.forename: D
authors.initials: D
authors.lastname: Wolke
mesh_terms: D000293:Adolescent; D002648:Child; D015331:Cohort Studies; D004325:Dreams / Q000523:psychology*; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D009035:Mothers; D020447:Parasomnias / Q000523:psychology*; D011618:Psychotic Disorders; D012307:Risk Factors; D006113:United Kingdom