title: Sustained improvements in fitness and exercise tolerance in obese adolescents after a 12 week exercise intervention.
abstract: A 12 week exercise program was evaluated for its effect on aerobic fitness, anaerobic threshold, physical activity and sedentary behavior levels in obese insulin resistant adolescents post intervention and at follow up. 111 obese insulin resistant 10-17 year olds were recruited to a 12 month lifestyle intervention, known as RESIST. From months 4 to 6, adolescents participated in supervised exercise sessions twice per week (45-60min/session). Aerobic fitness and anaerobic threshold were measured by gas analysis at baseline, 6 months (post intervention) and 12 months (follow up). Self-reported physical activity and sedentary behavior was measured using the CLASS questionnaire. At 6 months aerobic fitness and time to reach the anaerobic threshold had improved by 5.8% [95% CI: 0.8-11.3] and 19.7% [95% CI: 10.4-29.0], respectively compared with baseline. These improvements were maintained at 12 months. Compared to baseline, 6 month physical activity levels increased by 19min/day [95% CI: 5-33] and screen time decreased by 49min/day [95% CI: 23-74] but returned to baseline levels by 12 months. Improved fitness and anaerobic threshold can be sustained up to 6 months following completion of an exercise program possibly enhancing capacity to perform daily functional tasks.
authors.affiliation: The Children's Hospital at Westmead Clinical School, University of Sydney, Westmead, NSW 2145, Australia; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia. Electronic address: megan.gow@health.nsw.gov.au.
authors.forename: Megan L
authors.initials: ML
authors.lastname: Gow
authors.affiliation: School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia; The Children's Hospital Institute of Sports Medicine, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
authors.forename: Nancy
authors.initials: N
authors.lastname: van Doorn
authors.affiliation: School of Medical Sciences, University of New South Wales, Sydney, NSW, Australia; The Children's Hospital Institute of Sports Medicine, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
authors.forename: Carolyn R
authors.initials: CR
authors.lastname: Broderick
authors.affiliation: NSW Physical Activity, Nutrition and Obesity Research Group (PANORG), School of Public Health, University of Sydney, NSW 2006, Australia.
authors.forename: Louise L
authors.initials: LL
authors.lastname: Hardy
authors.affiliation: The Children's Hospital at Westmead Clinical School, University of Sydney, Westmead, NSW 2145, Australia; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
authors.forename: Mandy
authors.initials: M
authors.lastname: Ho
authors.affiliation: The Children's Hospital at Westmead Clinical School, University of Sydney, Westmead, NSW 2145, Australia; Kids Research Institute, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
authors.forename: Louise A
authors.initials: LA
authors.lastname: Baur
authors.affiliation: The Children's Hospital at Westmead Clinical School, University of Sydney, Westmead, NSW 2145, Australia; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia; Kids Research Institute, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
authors.forename: Chris T
authors.initials: CT
authors.lastname: Cowell
authors.affiliation: The Children's Hospital at Westmead Clinical School, University of Sydney, Westmead, NSW 2145, Australia; Institute of Endocrinology and Diabetes, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia; Kids Research Institute, The Children's Hospital at Westmead, Westmead, NSW 2145, Australia.
authors.forename: Sarah P
authors.initials: SP
authors.lastname: Garnett
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D002648:Child; D015444:Exercise / Q000502:physiology*; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D008297:Male; D063766:Pediatric Obesity / Q000503:physiopathology* / Q000628:therapy; D010809:Physical Fitness; D057185:Sedentary Behavior; D057566:Self Report
keywords: Adolescents; Aerobic fitness; Anaerobic threshold; Exercise tolerance; RESIST