title: Localized chrysiasis, aluminum salt deposition and dystrophic calcification a decade after gold injections.
abstract: Localized chrysiasis is rare and can occur in two settings: after localized or traumatic implantation of elemental gold or gold salts or after localized laser or light therapy in someone who has been previously exposed to systemic gold therapy. We report a unique case of localized chrysiasis with associated aluminum salt deposition and sclerosing lipogranulomas because of previous injections of aurothioglucose (Solganal®). The unique histopathologic findings seen in this case have not been previously reported.
authors.affiliation: Department of Dermatology, San Antonio Military Medical Center, San Antonio, TX, USA.
authors.forename: Lena E
authors.initials: LE
authors.lastname: Gowring
authors.affiliation: Department of Dermatology, San Antonio Military Medical Center, San Antonio, TX, USA.
authors.forename: Todd T
authors.initials: TT
authors.lastname: Kobayashi
authors.affiliation: Joint Pathology Center, US Army Forest Glen Annex, Silver Spring, MD, USA.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Lewin-Smith
mesh_terms: D000368:Aged; D000535:Aluminum / Q000378:metabolism*; D018501:Antirheumatic Agents / Q000008:administration & dosage / Q000009:adverse effects; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D006051:Aurothioglucose / Q000008:administration & dosage / Q000009:adverse effects*; D002114:Calcinosis / Q000139:chemically induced* / Q000378:metabolism / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000139:chemically induced* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D012859:Sjogren's Syndrome / Q000188:drug therapy
chemical_list: D018501:Antirheumatic Agents; D006051:Aurothioglucose; D000535:Aluminum
keywords: localized chrysiasis; sclerosing lipogranuloma