title: N-Heterocyclic carbene-catalyzed [2+3] cyclocondensation of α-chloroaldehydes with azomethine imines.
abstract: An N-heterocyclic carbene-catalyzed enantioselective [2+3] cyclocondensation of α-chloroaldehydes with azomethine imines was developed. The corresponding pyrazolidinones were obtained in good yields with moderate to good diastereoselectivities and excellent enantioselectivities.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. songye@iccas.ac.cn.
authors.forename: Zhong-Hua
authors.initials: ZH
authors.lastname: Gao
authors.forename: Xiang-Yu
authors.initials: XY
authors.lastname: Chen
authors.forename: Jin-Tang
authors.initials: JT
authors.lastname: Cheng
authors.forename: Wei-Lin
authors.initials: WL
authors.lastname: Liao
authors.forename: Song
authors.initials: S
authors.lastname: Ye