title: Dental management of a patient with Wilson's disease.
abstract: Wilson's disease (WD) is an autosomal recessive genetic disease, characterized by the accumulation of copper in the body--primarily in the brain and liver--due to defective biliary copper excretion by hepatocytes. WD may manifest clinically as liver disease, neurologic symptoms, and Kayser-Fleischer corneal rings. This article presents a case involving a 43-year-old man who had WD prior to liver transplantation. Oral examination revealed petechiae in the oral mucosa, poor oral hygiene, periodontal disease, missing teeth, and several carious teeth. Patients with WD may present systemic changes that affect dental care. Dental treatment prior to liver transplantation is recommended to eliminate the oral foci of infection and control oral disease.
authors.forename: Paulo Sergio
authors.initials: PS
authors.lastname: da Silva Santos
authors.forename: Karin Sa
authors.initials: KS
authors.lastname: Fernandes
authors.forename: Alexandre
authors.initials: A
authors.lastname: Fraige
authors.forename: Marina
authors.initials: M
authors.lastname: Gallottini
mesh_terms: D000328:Adult; D003729:Dental Care / Q000379:methods*; D003731:Dental Caries / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy; D003793:Dental Restoration, Permanent / Q000379:methods; D012534:Dental Scaling / Q000379:methods; D006527:Hepatolenticular Degeneration / Q000150:complications*; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D010510:Periodontal Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy; D011862:Radiography, Panoramic
keywords: Wilson's disease; coagulation abnormalities; liver transplantation