title: International Society for Cell Therapy Facility Sanitization Survey Laboratory Practices Committee Report.
abstract: OBJECTIVE
  Quality cell manufacturing processes require a clean laboratory environment.
  
  
  METHODS
  This report was aimed at describing current cleaning and sanitization practices reported by facilities that manufacture many types of cellular therapy products for clinical use. It is our hope that this report may provide the groundwork for guidance recommendations directed at developing consensus standards for cleaning and sanitization practices across the globe. Facility sanitization is a central issue to regulatory and accreditation bodies. Facilities are required to develop plans to assess sanitization practices and test cleaning effectiveness.
  
  
  RESULTS
  This document provides information on how this is performed in different facilities and may allow newer, smaller or less developed facilities to build, enhance or revise their current quality program by using experience and expertise in facility sanitization reported herein.
  
  
  CONCLUSIONS
  This report summarizes the results of the latest survey and compares results with those previously reported. New and relevant trends in the field provide important information and will provide important information for establishing guidelines.
authors.affiliation: Tel Aviv Sourasky Medical Center, The Hematology and Bone Marrow Transplant Laboratory, Tel Aviv, Israel.
authors.forename: Varda
authors.initials: V
authors.lastname: Deutsch
authors.affiliation: The Evelyn H. Griffin and the Judith R. Hoffberger cGMP Facilities, Program of Regenerative Medicine/University of Texas, Houston, Texas, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Havens
authors.affiliation: Massachusetts General Hospital, Boston, Massachusetts, USA. Electronic address: ksnow1@mgh.harvard.edu.
authors.forename: Karen
authors.initials: K
authors.lastname: Snow
mesh_terms: D064987:Cell- and Tissue-Based Therapy; D046508:Culture Techniques / Q000592:standards*; D004203:Disinfection / Q000379:methods*; D004780:Environment, Controlled; D006801:Humans; D007325:Institutional Practice; D007390:International Agencies; D007753:Laboratories / Q000592:standards*; D011795:Surveys and Questionnaires
keywords: classification; processing facilities; regulation; sanitization