title: THYRPAN-TM Prototype: New System for Online Telemonitoring of Patients with Thyroid Carcinoma During the Treatment with a High Dose of Radioiodine.
abstract: BACKGROUND
  Our team devised a real-time telemonitoring system (THYRPAN-TM) for measurement of the radiation exposure rate during the hospitalization of patients treated with high doses of radioiodine in the special premises with restricted access ("restricted area" [RA]).
  
  
  METHODS
  The THYRPAN-TM prototype was tested for stability, efficacy, and linearity in a 32-day measurement of a 110 MBq (131)I source. Furthermore, it was tested on 15 patients with differentiated thyroid carcinoma who stayed in the RA for 3 days, following their radioiodine treatment.
  
  
  RESULTS
  Minor deviation from the theoretical values was detected when the (131)I source was measured by the THYRPAN-TM, but only at the beginning of the measurement (7.20%).
  
  
  CONCLUSIONS
  THYRPAN-TM is a stable, user-friendly detection system for the measurement of the exposure rate following radioiodine administration. It enables the telemonitoring of patients, as well as real-time and online measurement of the whole-body burden of (131)I.
authors.affiliation: 1 Centre of Nuclear Medicine, Clinical Center Kragujevac and Faculty of Medical Sciences Kragujevac , University of Kragujevac, Kragujevac, Serbia .
authors.forename: Milovan D
authors.initials: MD
authors.lastname: Matovic
authors.affiliation: 1 Centre of Nuclear Medicine, Clinical Center Kragujevac and Faculty of Medical Sciences Kragujevac , University of Kragujevac, Kragujevac, Serbia .
authors.forename: Marija
authors.initials: M
authors.lastname: Jeremic
authors.affiliation: 2 Centre of Clinical Pharmacology, Clinical Center Kragujevac and Faculty of Medical Sciences Kragujevac , University of Kragujevac, Kragujevac, Serbia .
authors.forename: Slobodan
authors.initials: S
authors.lastname: Jankovic
authors.affiliation: 3 Faculty of Technical Sciences, University of Kragujevac , Cacak, Serbia .
authors.forename: Vlade
authors.initials: V
authors.lastname: Urosevic
authors.affiliation: 4 Prizma Company , Kragujevac, Serbia .
authors.forename: Miroslav
authors.initials: M
authors.lastname: Ravlic
authors.affiliation: 5 Center of Nuclear Medicine, Clinical Center Nis and Medical Faculty Nis , University of Nis, Nis, Serbia .
authors.forename: Marina
authors.initials: M
authors.lastname: Vlajkovic
mesh_terms: D004867:Equipment Design; D005260:Female; D006760:Hospitalization; D006801:Humans; D007457:Iodine Radioisotopes; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods*; D011874:Radiometry / Q000379:methods*; D011879:Radiotherapy Dosage; D013964:Thyroid Neoplasms / Q000532:radiotherapy*
chemical_list: D007457:Iodine Radioisotopes
keywords: radioiodine therapy; telemedicine; telemonitoring; thyroid cancer