title: [Molecular mechanisms of combined extremely radiofrequency and infrared therapy in various age patients with chronic parodontitis].
abstract: The influence of extreme radiofrequency millimeter microwave (EHF) and infrared (IR) electromagnetic emanation on the molecular markers of cell renovation (Ki67, p53) and proinflammatory cytokine TNF-α expression in the buccal cells of various age patients with chronic parodontitis was investigated. The results show that EHF- and IR-electromagnetic emanation increased Ki67 proliferative marker expression and decreased expression of proapoptosis protein p53 and proinflammatory cytokine TNF-α in the buccal epithelium of young, middle-aged and elderly people with chronic parodontitis. The data obtained open the new ability for patogenetic treatment of various age patients with chronic parodontitis using the EHF- and IR-electromagnetic emanation method.
authors.forename: O A
authors.initials: OA
authors.lastname: Ianova
authors.forename: D S
authors.initials: DS
authors.lastname: Medvedev
authors.forename: N S
authors.initials: NS
authors.lastname: Lin'kova
authors.forename: N I
authors.initials: NI
authors.lastname: Trifonov
authors.forename: M M
authors.initials: MM
authors.lastname: D'iakonov
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism* / Q000473:pathology; D002908:Chronic Disease; D055113:Chronic Periodontitis / Q000378:metabolism / Q000473:pathology / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D006801:Humans; D007150:Immunohistochemistry; D007259:Infrared Rays / Q000627:therapeutic use*; D019394:Ki-67 Antigen / Q000378:metabolism; D008872:Microwaves / Q000627:therapeutic use*; D008875:Middle Aged; D009061:Mouth Mucosa / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism
chemical_list: D019394:Ki-67 Antigen; D014409:Tumor Necrosis Factor-alpha; D016159:Tumor Suppressor Protein p53