title: Electrical stimulation mapping of nouns and verbs in Broca's area.
abstract: Electric stimulation mapping (ESM) is frequently used during brain surgery to localise higher cognitive functions to avoid post-chirurgical disabilities. Experiments with brain imaging techniques and neuropsychological studies showed differences in the cortical representation and processing of nouns and verbs. The goal of the present study was to investigate whether electric stimulation in specific sites in the frontal cortex disrupted noun and verb production selectively. We found that most of the stimulated areas showed disruption of both verbs and nouns at the inferior frontal gyrus. However, when selective effects were obtained, verbs were more prone to disruption than nouns with important individual differences. The overall results indicate that selective impairments can be observed at inferior and middle frontal regions and the action naming task seems to be more suitable to avoid post-chirurgical language disabilities, as it shows a greater sensitivity to disruption with ESM than the classical object naming task.
authors.affiliation: Cognition and Brain Plasticity Group [Bellvitge Biomedical Research Institute-] IDIBELL, L'Hospitalet de Llobregat, Barcelona 08097, Spain; Dept. of Basic Psychology, Campus Bellvitge, University of Barcelona, L'Hospitalet de Llobregat, Barcelona 08097, Spain. Electronic address: viktoria.havas@gmail.com.
authors.forename: Viktória
authors.initials: V
authors.lastname: Havas
authors.affiliation: Hospital Universitari de Bellvitge (HUB), Neurosurgery Section, Campus Bellvitge, University of Barcelona - IDIBELL, 08097 L'Hospitalet (Barcelona), Spain.
authors.forename: Andreu
authors.initials: A
authors.lastname: Gabarrós
authors.affiliation: Hospital Universitari de Bellvitge (HUB), Neurology Section, Campus Bellvitge, University of Barcelona - IDIBELL, 08097 L'Hospitalet (Barcelona), Spain.
authors.forename: Montserrat
authors.initials: M
authors.lastname: Juncadella
authors.affiliation: Cognition and Brain Plasticity Group [Bellvitge Biomedical Research Institute-] IDIBELL, L'Hospitalet de Llobregat, Barcelona 08097, Spain.
authors.forename: Xavi
authors.initials: X
authors.lastname: Rifa-Ros
authors.affiliation: Hospital Universitari de Bellvitge (HUB), Neurosurgery Section, Campus Bellvitge, University of Barcelona - IDIBELL, 08097 L'Hospitalet (Barcelona), Spain.
authors.forename: Gerard
authors.initials: G
authors.lastname: Plans
authors.affiliation: Hospital Universitari de Bellvitge (HUB), Neurosurgery Section, Campus Bellvitge, University of Barcelona - IDIBELL, 08097 L'Hospitalet (Barcelona), Spain.
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Acebes
authors.affiliation: Cognition and Brain Plasticity Group [Bellvitge Biomedical Research Institute-] IDIBELL, L'Hospitalet de Llobregat, Barcelona 08097, Spain; Dept. of Basic Psychology, Campus Bellvitge, University of Barcelona, L'Hospitalet de Llobregat, Barcelona 08097, Spain; Catalan Institution for Research and Advanced Studies, ICREA, Barcelona, Spain.
authors.forename: Ruth
authors.initials: R
authors.lastname: de Diego Balaguer
authors.affiliation: Cognition and Brain Plasticity Group [Bellvitge Biomedical Research Institute-] IDIBELL, L'Hospitalet de Llobregat, Barcelona 08097, Spain; Dept. of Basic Psychology, Campus Bellvitge, University of Barcelona, L'Hospitalet de Llobregat, Barcelona 08097, Spain; Catalan Institution for Research and Advanced Studies, ICREA, Barcelona, Spain.
authors.forename: Antoni
authors.initials: A
authors.lastname: Rodríguez-Fornells
mesh_terms: D000328:Adult; D000368:Aged; D001931:Brain Mapping / Q000379:methods*; D065711:Broca Area / Q000502:physiology*; D004558:Electric Stimulation / Q000379:methods; D005260:Female; D005625:Frontal Lobe / Q000502:physiology; D006801:Humans; D007802:Language; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation / Q000379:methods; D012660:Semantics
keywords: Broca’s area; Electric stimulation mapping; Verbs and nouns