title: High grade serous ovarian carcinoma with serous tubal intraepithelial carcinoma in a case presented with atypical glandular cell favor neoplasm cervical cytology and dermatomyositis.
abstract: OBJECTIVE
  This report describes a case of serous ovarian carcinoma with occult serous tubal intraepithelial carcinoma (STIC), which presented as atypical glandular cells favor neoplasia (AGC-FN) with Pap cytology and dermatomyositis.
  
  
  METHODS
  A 48-year-old woman presented with symptoms of dermatomyositis. An AGC-FN result from a Pap smear, with an absence of a cervical or endometrial lesion was noted. After cancer surveillance, ovarian high grade serous carcinoma associated with serous tubal intraepithelial carcinoma was diagnosed. Two weeks following surgical excision of the carcinoma, dramatic remission of the dermatomyositis symptoms was evident.
  
  
  CONCLUSIONS
  The patient had serous carcinoma of the ovary with tubal STIC, which presented as dermatomyositis. The AGC-FN identified from a Pap smear hinted at a diagnosis of ovarian carcinoma. These presentations point to an occult malignancy in the genital tract and demand careful diagnostic workup.
authors.affiliation: Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan; Graduate Institute of Medical Science, Tzu Chi University, Hualien, Taiwan.
authors.forename: Mun-Kun
authors.initials: MK
authors.lastname: Hong
authors.affiliation: Department of Pathology, Buddhist Tzu Chi General Hospital and University, Hualien, Taiwan.
authors.forename: Ming-Hsun
authors.initials: MH
authors.lastname: Lee
authors.affiliation: Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
authors.forename: Dah-Ching
authors.initials: DC
authors.lastname: Ding
authors.affiliation: Department of Hematology-Oncology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
authors.forename: Sung-Chao
authors.initials: SC
authors.lastname: Chu
authors.affiliation: Department of Obstetrics and Gynecology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan; Graduate Institute of Medical Science, Tzu Chi University, Hualien, Taiwan. Electronic address: hidrchu@gmail.com.
authors.forename: Tang-Yuan
authors.initials: TY
authors.lastname: Chu
mesh_terms: D002278:Carcinoma in Situ / Q000150:complications / Q000175:diagnosis*; D002584:Cervix Uteri / Q000473:pathology; D018284:Cystadenocarcinoma, Serous / Q000150:complications / Q000175:diagnosis*; D003882:Dermatomyositis / Q000175:diagnosis / Q000209:etiology*; D005185:Fallopian Tube Neoplasms / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D060787:Neoplasm Grading; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000175:diagnosis*; D010051:Ovarian Neoplasms / Q000150:complications / Q000175:diagnosis*; D065006:Papanicolaou Test; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000209:etiology*; D014626:Vaginal Smears
keywords: atypical glandular cell; dermatomyositis; p53 signature; serous tubal intraepithelial carcinoma