title: Current status and clinical development of transcatheter approaches for severe mitral regurgitation.
abstract: Transcatheter mitral valve intervention has emerged as an effective treatment option for symptomatic severe mitral regurgitation in patients considered to be inoperable or at high operative risk for surgical mitral valve surgery. Most transcatheter approaches are modifications of existing surgical approaches. Transcatheter edge-to-edge mitral valve repair with the MitraClip system has the largest clinical experience to date, as it offers a sustained clinical benefit in selected patients. This review aims to provide an up-to-date overview of transcatheter mitral valve interventions, including leaflet repair, annuloplasty, and mitral valve implantation.
authors.affiliation: Department of Cardiology, Ferrarotto Hospital, University of Catania.
authors.forename: Carmelo
authors.initials: C
authors.lastname: Grasso
authors.forename: Davide
authors.initials: D
authors.lastname: Capodanno
authors.forename: Corrado
authors.initials: C
authors.lastname: Tamburino
authors.forename: Yohei
authors.initials: Y
authors.lastname: Ohno
mesh_terms: D000368:Aged; D006328:Cardiac Catheterization / Q000379:methods*; D002815:Chordae Tendineae; D057510:Endovascular Procedures / Q000295:instrumentation / Q000379:methods*; D005544:Forecasting; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D058386:Mitral Valve Annuloplasty / Q000295:instrumentation / Q000379:methods*; D008944:Mitral Valve Insufficiency / Q000601:surgery*; D019736:Prostheses and Implants; D011474:Prosthesis Design; D012307:Risk Factors; D013318:Stroke Volume; D013525:Surgical Instruments; D020257:Ventricular Remodeling