title: Laparoscopic Sentinel Node Biopsy Using Real-time 3-dimensional Single-photon Emission Computed Tomographic Guidance in Endometrial Cancer.
abstract: In endometrial cancer, the histopathological analysis of the lymphatic nodes is essential to establish a correct prognosis and tailored adjuvant treatment. It is well-known that patients with early-stage endometrial cancer have a low incidence of nodal disease. In this group, systematic lymphadenectomy is not recommended. To improve the detection rate of sentinel nodes in clinical practice, new techniques are emerging like real-time 3-dimensional single-photon emission computed tomographic (SPECT) imaging. We report our experience using this innovative technique for intraoperative detection of sentinel nodes in endometrial cancer. The real-time 3-dimensional SPECT sentinel node biopsy seems to be feasible and accurate in endometrial cancer although further studies are needed to set the precision and predictive values compared with the current differed SPECT techniques and blue dye techniques.
authors.affiliation: Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain.
authors.forename: Sara
authors.initials: S
authors.lastname: Fernandez-Prada
authors.affiliation: Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain.
authors.forename: Elsa
authors.initials: E
authors.lastname: Delgado-Sanchez
authors.affiliation: Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: De Santiago
authors.affiliation: Gynecologic Oncology Unit, La Paz University Hospital, Madrid, Spain. Electronic address: ignaciozapardiel@hotmail.com.
authors.forename: Ignacio
authors.initials: I
authors.lastname: Zapardiel
mesh_terms: D000368:Aged; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008197:Lymph Node Excision / Q000379:methods*; D008198:Lymph Nodes / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D021701:Sentinel Lymph Node Biopsy / Q000379:methods*; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed / Q000379:methods
keywords: 3-dimensional single-photon emission computed tomography; Endometrial cancer; Sentinel node biopsy