title: First Clinical Evaluation of High-Pitch Dual-Source Computed Tomographic Angiography Comparing Automated Tube Potential Selection With Automated Tube Current Modulation.
abstract: OBJECTIVE
  To investigate and compare the use of automated tube potential selection (ATPS) with automated tube current modulation (ATCM) in high-pitch dual-source computed tomographic angiography (CTA) for imaging the whole aorta without electrocardiogram synchronization.
  
  
  METHODS
  Two groups of 60 patients underwent CTA on a dual-source computed tomographic device in high-pitch mode: ATCM (with 100-kV fixed tube potential) was used in group 1 and ATPS (with the same image quality options) in group 2. For the evaluation of radiation exposure, CT dose index and dose-length product were analyzed. Contrast and image quality were assessed by 2 independent observers.
  
  
  RESULTS
  The ATPS group received a higher radiation dose than the ATCM group (P < 0.001) because in 80% of patients, the software switched to use of a 120-kV tube potential. In all cases, images of the aorta were of sufficient quality.
  
  
  CONCLUSIONS
  High-pitch dual-source CTA of the aorta using ATPS is feasible in clinical routine, but is associated with higher radiation exposure than the ATCM protocol. This finding contradicts previously evaluations of ATPS based on single-source techniques.
authors.affiliation: From the *Department of Diagnostic and Interventional Radiology, Clinic of the Goethe University, Frankfurt, Germany; and †Department of Diagnostic and Interventional Radiology, Cairo University Hospital, Cairo, Egypt.
authors.forename: Martin
authors.initials: M
authors.lastname: Beeres
authors.forename: Kimberly
authors.initials: K
authors.lastname: Williams
authors.forename: Ralf W
authors.initials: RW
authors.lastname: Bauer
authors.forename: Jan
authors.initials: J
authors.lastname: Scholtz
authors.forename: Moritz
authors.initials: M
authors.lastname: Kaup
authors.forename: Tatjana
authors.initials: T
authors.lastname: Gruber-Rouh
authors.forename: Clara
authors.initials: C
authors.lastname: Lee
authors.forename: Julian L
authors.initials: JL
authors.lastname: Wichmann
authors.forename: Claudia
authors.initials: C
authors.lastname: Frellesen
authors.forename: Nour-Eldin A
authors.initials: NE
authors.lastname: Nour-Eldin
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Vogl
authors.forename: Josef Matthias
authors.initials: JM
authors.lastname: Kerl
authors.forename: Boris
authors.initials: B
authors.lastname: Bodelle
mesh_terms: D001027:Aortography / Q000295:instrumentation / Q000379:methods; D003287:Contrast Media; D005260:Female; D006801:Humans; D007479:Iopamidol / Q000031:analogs & derivatives; D008297:Male; D015588:Observer Variation; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D059629:Signal-To-Noise Ratio; D014057:Tomography, X-Ray Computed / Q000295:instrumentation* / Q000379:methods*; D051598:Whole Body Imaging / Q000295:instrumentation / Q000379:methods
chemical_list: D003287:Contrast Media; C057937:iomeprol; D007479:Iopamidol