title: Impact of dietary plane of energy during the dry period on lipoprotein parameters in the transition period in dairy cattle.
abstract: The high energy demands of dairy cows during the transition period from late gestation into early lactation can place them at an increased risk for the development of metabolic and infectious diseases. Modification of the dry period diet has been investigated as a preventive means to minimize the detrimental aspects of metabolic shifts during the transition period. Studies investigating the impact of dry period diet on lipid parameters during the transition period have largely focused on markers of lipolysis and ketogenesis. Total cholesterol declines during the periparturient period and increases in early lactation. The impact total energy in the dry period diet has on the ability of the cow to maintain total serum cholesterol, as well as its natural high-density lipoprotein-rich status, during this metabolically challenging window is not clear. The impact of lipoproteins on inflammation and immune function may have a clinical impact on the cow's ability to ward off production-related diseases. In this study, we hypothesized that the provision of adequate, but not excessive, total metabolizable energy, would better allow the cow to maintain total cholesterol and a higher relative proportion of HDL throughout the transition period. Cows were allocated to one of three dry period dietary treatment groups following a randomized block design. Total serum triglycerides, cholesterol and lipoprotein fractions were measured on a weekly basis from approximately 7 weeks pre-calving to 6 weeks post-calving. The cows on the high energy diet maintained total serum cholesterol as compared to the cows provided a lower energy diet, but there was no significant increase in the LDL fraction of lipoproteins between diet treatment groups.
authors.affiliation: Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
authors.forename: A
authors.initials: A
authors.lastname: Newman
authors.affiliation: Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
authors.forename: S
authors.initials: S
authors.lastname: Mann
authors.affiliation: Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
authors.forename: D V
authors.initials: DV
authors.lastname: Nydam
authors.affiliation: Department of Animal Science, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY, USA.
authors.forename: T R
authors.initials: TR
authors.lastname: Overton
authors.affiliation: Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
authors.forename: E
authors.initials: E
authors.lastname: Behling-Kelly
mesh_terms: D000821:Animal Feed / Q000032:analysis*; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002417:Cattle / Q000502:physiology*; D004032:Diet / Q000662:veterinary*; D004586:Electrophoresis; D002149:Energy Intake / Q000502:physiology*; D005260:Female; D007774:Lactation / Q000502:physiology*; D008074:Lipoproteins / Q000378:metabolism
chemical_list: D008074:Lipoproteins
keywords: cholesterol; high-density lipoproteins; low-density lipoproteins; negative energy balance; triglycerides