title: Effectiveness of body-mind-spirit intervention on well-being, functional impairment and quality of life among depressive patients - a randomized controlled trial.
abstract: OBJECTIVE
  The aim of the study was to examine the efficacy of body-mind-spirit Intervention in improving the outcomes (well-being, quality of life and functional impairment) among depressive patients.
  
  
  BACKGROUND
  Depressive disorders lead to significant dysfunction, disability and poor quality of life among sufferers. Body-mind-spirit intervention has been associated with improvements in the outcomes; however, few studies have examined this among depressive patients.
  
  
  METHODS
  True experimental pre-post equivalent groups design was adopted with longitudinal measurement of outcomes.
  
  
  METHODS
  Participants were 120 adult depressive patients visiting the psychiatric outpatient department in a District Hospital in India. The participants were randomly assigned to either the body-mind-spirit group or the treatment-as-usual group between July 2011-January 2013. The treatment-as-usual group (n = 64) received only routine treatment (antidepressants and structured psycho-education) in the hospital. The body-mind-spirit group (n = 56) received four weekly body-mind-spirit group sessions in addition to the routine treatment. Outcome measures on depression, well-being, functional impairment and quality of life were evaluated for both groups at baseline and at four follow-up assessments in the 1st, 2nd, 3rd and 6th month. Treatment effects of the body-mind-spirit intervention were analysed by repeated-measures analysis of covariance.
  
  
  RESULTS
  Compared with the treatment-as-usual group, the body-mind-spirit group showed significant reduction in depression and functional impairment, and significant improvement in the well-being and quality of life scores over the 6-month study period.
  
  
  CONCLUSIONS
  The present findings provided evidence for the effectiveness of integrating a complementary therapy such as the body-mind-spirit intervention with conventional treatment in improving prospective outcomes among the depressive patients.
authors.affiliation: Department of Psychiatric Nursing, Dharwad Institute of Mental Health and Neurosciences, India.
authors.forename: Sreevani
authors.initials: S
authors.lastname: Rentala
authors.affiliation: Centre on Behavioral Health, The University of Hong Kong, Hong Kong.
authors.forename: Ted C T
authors.initials: TC
authors.lastname: Fong
authors.affiliation: Department of Nursing, National Institute of Mental Health and Neurosciences, Bangalore, India.
authors.forename: Prasanthi
authors.initials: P
authors.lastname: Nattala
authors.affiliation: Department of Social Work and Social Administration, The University of Hong Kong, Hong Kong.
authors.forename: Cecilia L W
authors.initials: CL
authors.lastname: Chan
authors.affiliation: Department of Nursing, National Institute of Mental Health and Neurosciences, Bangalore, India.
authors.forename: Reddemma
authors.initials: R
authors.lastname: Konduru
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use; D003863:Depression / Q000188:drug therapy / Q000503:physiopathology* / Q000523:psychology*; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D011788:Quality of Life
chemical_list: D000928:Antidepressive Agents
keywords: body-mind connection; body-mind-spirit intervention; complementary therapies; depression; functional impairment; holistic care; nurse; psychiatric nursing; quality of life; well-being