title: Surgical treatment of lumbosacral tuberculosis by one-stage debridement and anterior instrumentation with allograft through an extraperitoneal anterior approach.
abstract: BACKGROUND
  This study was aimed to investigate the clinical outcome of lumbosacral tuberculosis treatment by one-stage radical debridement with bone allograft reconstruction and anterior instrumentation via a retroperitoneal approach.
  
  
  METHODS
  We retrospectively analyzed a series of 43 patients with lumbosacral tuberculosis in whom the lumbosacral junction was exposed via an anterior midline retroperitoneal approach. After radical debridement, two parallel tricortical iliac crest bone allografts were placed to reconstruct the anterior column, and then anterior fixation was performed.
  
  
  RESULTS
  The mean follow-up period was 34 months (range, 24-91 months), during which no obvious loss of correction was observed. No case experienced recurrence, tuberculous peritonitis, erectile dysfunction, or retrograde ejaculation.
  
  
  CONCLUSIONS
  The midline retroperitoneal approach provides direct and safe access to lesions of lumbosacral tuberculosis. Two parallel structural iliac crest allografts and anterior instrumentation effectively stabilize the lumbosacral junction.
authors.affiliation: Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Gaotanyan Street 29, Shapingba District, Chongqing, 400038, China. 421311493@qq.com.
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Li
authors.affiliation: Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Gaotanyan Street 29, Shapingba District, Chongqing, 400038, China. zhangzehuatmmu@qq.com.
authors.forename: Ze-Hua
authors.initials: ZH
authors.lastname: Zhang
authors.affiliation: Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Gaotanyan Street 29, Shapingba District, Chongqing, 400038, China. shitaostone@hotmail.com.
authors.forename: Tao
authors.initials: T
authors.lastname: Shi
authors.affiliation: Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Gaotanyan Street 29, Shapingba District, Chongqing, 400038, China. david-feifei@163.com.
authors.forename: Fei
authors.initials: F
authors.lastname: Dai
authors.affiliation: Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Gaotanyan Street 29, Shapingba District, Chongqing, 400038, China. zq_tlh@163.com.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhou
authors.affiliation: Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Gaotanyan Street 29, Shapingba District, Chongqing, 400038, China. luofly1009@21cn.com.
authors.forename: Fei
authors.initials: F
authors.lastname: Luo
authors.affiliation: Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Gaotanyan Street 29, Shapingba District, Chongqing, 400038, China. tianyonghou@126.com.
authors.forename: Tian-Yong
authors.initials: TY
authors.lastname: Hou
authors.affiliation: Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Gaotanyan Street 29, Shapingba District, Chongqing, 400038, China. 1349831917@qq.com.
authors.forename: Qing-Yi
authors.initials: QY
authors.lastname: He
authors.affiliation: National & Regional United Engineering Laboratory of Tissue Engineering, Southwest Hospital, Third Military Medical University, Chongqing, China. 273559011@qq.com.
authors.forename: Mo-Yuan
authors.initials: MY
authors.lastname: Deng
authors.affiliation: Department of Orthopaedics, Southwest Hospital, Third Military Medical University, Gaotanyan Street 29, Shapingba District, Chongqing, 400038, China. xujianzhong2014@163.com.
authors.forename: Jian-Zhong
authors.initials: JZ
authors.lastname: Xu
mesh_terms: D000328:Adult; D000368:Aged; D016025:Bone Transplantation / Q000379:methods*; D003646:Debridement / Q000379:methods*; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013123:Spinal Fusion / Q000295:instrumentation*; D014184:Transplantation, Homologous; D014399:Tuberculosis, Spinal / Q000601:surgery*; D055815:Young Adult