title: Elastography in pancreatic solid tumours diagnoses.
abstract: BACKGROUND
  Pancreatic solid tumour diagnoses remain a challenge for modern medicine. However, using endosonography together with elastography helps to examine the elasticity of tissues and therefore may allow definition of the nature of pancreatic tumours.
  
  
  OBJECTIVE
  To evaluate the usefulness of elastography with the strain ratio method and quantitative evaluation of pancreatic solid tumours.
  
  
  METHODS
  A total of 54 patients with pancreatic solid tumours were treated with ultrasound endosonography with fine-needle aspiration biopsy. The control group contained 26 patients with normal pancreas. Pancreatic solid tumours and normal pancreas were analysed with elastography and elasticity evaluation of the interest area (A), reference (B), and the strain ratio factor (B/A). Postoperative histopathological or cytological examinations were the final diagnoses. Both postoperative and cytological diagnoses were compared with average elasticity parameters (A) and strain ratio factors (B/A).
  
  
  RESULTS
  Average elasticity parameters (A) and the strain ratio factors (B/A) were: 0.025% (0.01-0.05%) for malignant process, and (B/A) 33.93 (18.23-75.45); (A) - 0.26% (0.14-0.35%), and (B/A) 5.35 (3.47-7.8) for inflammatory process; (A) 0.54% (0.35-0.82%), and (B/A) 1.79 (1.02-2.05) for normal pancreatic tissue.
  
  
  CONCLUSIONS
  Malignant tumours have higher tightness factor compared to inflammatory tumours and normal pancreatic tissue. Elasticity parameters reach the highest levels in normal pancreatic tissue, lower in inflammatory tumours, and the lowest in malignant tumours.
authors.affiliation: Department of Gastroenterology, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Przemysław
authors.initials: P
authors.lastname: Dyrla
authors.affiliation: Department of Gastroenterology, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Gil
authors.affiliation: Department of Gastroenterology, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Michał
authors.initials: M
authors.lastname: Florek
authors.affiliation: Department of Internal Medicine, Nephrology and Dialysis, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Saracyn
authors.affiliation: Department of Pathology, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Bartłomiej
authors.initials: B
authors.lastname: Grala
authors.affiliation: Department of General Surgery, Oncology, Metabolic and Thoracic Surgery, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Emil
authors.initials: E
authors.lastname: Jędrzejewski
authors.affiliation: Department of Gastroenterology, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Stanisław
authors.initials: S
authors.lastname: Wojtuń
authors.affiliation: Department of Internal Medicine, Nephrology and Dialysis, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Arkadiusz
authors.initials: A
authors.lastname: Lubas
keywords: elasticity; elastography; endosonography; strain ratio