title: Nephrotic syndrome and renal failure as an unusual presentation of solid tumour.
abstract: Glomerular diseases may occur as primary manifestation of cancer, especially in patients older than 60 years. Among glomerulopathies, membranous nephropathy is preferentially associated with respiratory and gastrointestinal tract adenocarcinomas, whereas minimal change disease is most often seen in haematological malignancies. Though breast cancer is one of the most frequent malignancies in women, paraneoplastic glomerular disease is rarely observed. We describe the case of a 79-year-old female patient who presented with nephrotic syndrome and renal failure. Breast cancer was found. Pathological studies of kidney and breast biopsy revealed a minimal change disease and an infiltrating ductal carcinoma, respectively.
authors.affiliation: Departments of Nephrology.
authors.forename: Florence
authors.initials: F
authors.lastname: Bonkain
authors.affiliation: Gynaecology.
authors.forename: Graziella
authors.initials: G
authors.lastname: Ena
authors.affiliation: Pathology, Erasme Hospital , Université Libre de Bruxelles , Brussels.
authors.forename: Michel
authors.initials: M
authors.lastname: Depierreux
authors.affiliation: Department of Nephrology and Dialysis , RHMS Baudour Hospital, Baudour , Belgium.
authors.forename: Frédéric D
authors.initials: FD
authors.lastname: Debelle
authors.affiliation: Departments of Nephrology.
authors.forename: Joëlle L
authors.initials: JL
authors.lastname: Nortier
keywords: acute kidney injury; minimal change disease; nephrotic syndrome; paraneoplastic glomerulopathy; solid tumour