title: Can CT angiography reconstructed from CT perfusion source data on a 320-section volume CT scanner replace conventional CT angiography for the evaluation of intracranial arteries?
abstract: OBJECTIVE
  To compare conventional CT angiography (CTA) and CTA reconstructed from CT perfusion source data (perfusion CTA) acquired on a 320-section CT scanner for the evaluation of intracranial arteries.
  
  
  METHODS
  Our study included 7 patients who had undergone trapping of an intracranial aneurysm and placement of a bypass. All underwent conventional and perfusion CTA and digital subtraction angiography (DSA). Using DSA as the gold standard, 2 radiologists evaluated 10 arterial segments on conventional and perfusion CTA images. On a 4-point scale they independently scored the image quality and vascular visualization of the intracranial arteries on the conventional and perfusion CTA images. The effective radiation dose to each patient was also recorded.
  
  
  RESULTS
  A total of 65 arterial segments without apparent abnormalities were assessed. While the mean image quality score tended to be slightly higher for conventional than perfusion CTA, there was no significant difference. The effective dose for perfusion and conventional CTA with unenhanced CT was 4.2 mSv and 3.1 mSv, respectively, for all patients.
  
  
  CONCLUSIONS
  For the evaluation of intracranial arteries using DSA as the gold standard, perfusion CTA yields image quality and vascular visualization similar to conventional CTA at an acceptable radiation dose.
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan, masafkidoh@yahoo.co.jp.
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kidoh
authors.forename: Toshinori
authors.initials: T
authors.lastname: Hirai
authors.forename: Seitaro
authors.initials: S
authors.lastname: Oda
authors.forename: Daisuke
authors.initials: D
authors.lastname: Utsunomiya
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kawano
authors.forename: Shigetoshi
authors.initials: S
authors.lastname: Yano
authors.forename: Hideo
authors.initials: H
authors.lastname: Nakamura
authors.forename: Keishi
authors.initials: K
authors.lastname: Makino
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Iryo
authors.forename: Minako
authors.initials: M
authors.lastname: Azuma
authors.forename: Eri
authors.initials: E
authors.lastname: Hayashida
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakaura
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yamashita
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D002533:Cerebral Angiography / Q000379:methods*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*