title: Sparganosis presenting as pericardial effusion and lung lesions.
abstract: We herein report a rare form of sparganosis in a 29-year-old man presenting with pericardial effusion and lung lesions. The diagnosis was confirmed by the patient's history of eating inadequately cooked snake, significant elevated eosinophils in the peripheral blood and pericardial effusion, and marked positive reactions against Sparganum mansoni antigen in the serum. After two consecutive doses of praziquantel treatment, the patient's symptoms and laboratory and imaging findings were improved. Both specific antibody detection and follow-up of the patient's eosinophils, serum antibody, and imaging changes are important for sparganosis diagnosis, particularly in cases without a subcutaneous lump or mass.
authors.affiliation: Shanghai Institution of Cardiovascular Disease, Department of Cardiology, Zhongshan Hospital, Fudan University, China.
authors.forename: Xueying
authors.initials: X
authors.lastname: Chen
authors.forename: Jin
authors.initials: J
authors.lastname: Bai
authors.forename: Jingfeng
authors.initials: J
authors.lastname: Wang
authors.forename: Kuan
authors.initials: K
authors.lastname: Cheng
authors.forename: Chunmei
authors.initials: C
authors.lastname: Shen
authors.forename: Haohua
authors.initials: H
authors.lastname: Yao
authors.forename: Bin
authors.initials: B
authors.lastname: Tang
authors.forename: Juying
authors.initials: J
authors.lastname: Qian
mesh_terms: D000328:Adult; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents; D000909:Antibodies, Helminth; D003907:Dexamethasone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004562:Electrocardiography; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008460:Meat / Q000469:parasitology; D010490:Pericardial Effusion / Q000209:etiology* / Q000469:parasitology; D011223:Praziquantel / Q000627:therapeutic use*; D012911:Snakes / Q000469:parasitology; D013031:Sparganosis / Q000150:complications / Q000175:diagnosis*; D013032:Sparganum / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics; D000893:Anti-Inflammatory Agents; D000909:Antibodies, Helminth; D011223:Praziquantel; D003907:Dexamethasone