title: Enhancement of cancer specific delivery using ultrasound active bio-originated particles.
abstract: A hybrid multifunctional particle comprising of a microbbule (MB), liposome (Lipo), and an Fe ion chelated melanin nanoparticle (MNP(Fe)) was applied for ultrasound mediated cancer targeting as a theranostic agent.
authors.affiliation: Department of Radiology, Seoul National University College of Medicine and Seoul National University Bundang Hospital, Seungnam 463-707, South Korea.
authors.forename: Young Il
authors.initials: YI
authors.lastname: Yoon
authors.forename: Kook Yun
authors.initials: KY
authors.lastname: Ju
authors.forename: Hee-Sang
authors.initials: HS
authors.lastname: Cho
authors.forename: Kyeong Nam
authors.initials: KN
authors.lastname: Yu
authors.forename: Jae Jun
authors.initials: JJ
authors.lastname: Lee
authors.forename: Gook Jun
authors.initials: GJ
authors.lastname: Ahn
authors.forename: Soo-Hong
authors.initials: SH
authors.lastname: Lee
authors.forename: Myung Haing
authors.initials: MH
authors.lastname: Cho
authors.forename: Hak Jong
authors.initials: HJ
authors.lastname: Lee
authors.forename: Jin-Kyu
authors.initials: JK
authors.lastname: Lee
authors.forename: Tae-Jong
authors.initials: TJ
authors.lastname: Yoon
mesh_terms: D045744:Cell Line, Tumor; D016503:Drug Delivery Systems; D006801:Humans; D051034:Inhibitor of Apoptosis Proteins / Q000235:genetics; D007501:Iron / Q000008:administration & dosage*; D008081:Liposomes; D008543:Melanins / Q000008:administration & dosage*; D045423:Microbubbles; D053758:Nanoparticles / Q000008:administration & dosage*; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism; D034741:RNA, Small Interfering / Q000008:administration & dosage; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism; D000077022:Survivin; D014465:Ultrasonics
chemical_list: D051034:Inhibitor of Apoptosis Proteins; D007501:Iron; D008081:Liposomes; D008543:Melanins; D034741:RNA, Small Interfering; D018719:Erb-b2 Receptor Tyrosine Kinases; D000077022:Survivin; C107489:BIRC5 protein, human; C508053:ERBB2 protein, human