title: Neurovascular reconstruction with flow diverter stents for the treatment of 87 intracranial aneurysms: Clinical results.
abstract: BACKGROUND
  Flow diverter stents represent a new endovascular tool to treat complex aneurysms, such as giant, large, wide-necked and fusiform. The highly dense mash of these stents reduces inflow and outflow inside the aneurysm, resulting in intra aneurysmal thrombosis and stent endothelialization.
  
  
  OBJECTIVE
  To present the results of treatment of intracranial aneurysms with flow diverter stents in a single center.
  
  
  METHODS
  Retrospective review of 77 patients with 87 aneurysms treated using two different types of flow diverter stent, the Pipeline Embolization Device and SILK stent, between October 2010 and September 2013 in an interventional neuroradiology center.
  
  
  RESULTS
  Flow diverter stent placement was successful in 98% of the lesions and resulted in an immediate major stasis within most of the treated aneurysms. The overall aneurysm occlusion rate at six months and 18 months was 80% and 84% respectively. Symptomatic complications occurred in 11 patients (14.3%) with morbidity in eight (10.4%) and mortality in three patients (3.9%).
  
  
  CONCLUSIONS
  Flow diversion is a promising technique for treatment of challenging intracranial aneurysms with acceptable morbidity. A high rate of complete occlusion for small large necked aneurysms, a low morbidity and mortality rate and no recanalization encourage their use in these aneurysms. Further studies accessing long-term aneurysm occlusion and recanalization are required.
authors.affiliation: Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil leogiacomini@yahoo.com.br.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Giacomini
authors.affiliation: Centro de NeuroAngiografia (CNA), Hospital Beneficencia Portuguesa de São Paulo, São Paulo, Brazil.
authors.forename: Ronie L
authors.initials: RL
authors.lastname: Piske
authors.affiliation: Centro de NeuroAngiografia (CNA), Hospital Beneficencia Portuguesa de São Paulo, São Paulo, Brazil.
authors.forename: Carlos E
authors.initials: CE
authors.lastname: Baccin
authors.affiliation: Centro de NeuroAngiografia (CNA), Hospital Beneficencia Portuguesa de São Paulo, São Paulo, Brazil.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Barroso
authors.affiliation: Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil.
authors.forename: Andrei F
authors.initials: AF
authors.lastname: Joaquim
authors.affiliation: Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil.
authors.forename: Helder
authors.initials: H
authors.lastname: Tedeschi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome
keywords: Aneurysm; Pipeline; SILK; endovascular; flow diverter stent