title: Colovesical fistula: should it be considered a single disease?
abstract: OBJECTIVE
  This research was conducted to compare the management and the outcome of patients with colovesical fistulae of different aetiologies.
  
  
  METHODS
  Retrospective data were collected from 2002 to 2012 and analyzed with SPSS ver. 17. Age, gender, aetiology, management, hospital stay, postoperative complications, and mortality were studied and compared among colovesical fistulae of different aetiologies.
  
  
  RESULTS
  A total of 55 patients, 46 males (84%) and 9 females (16%), with a median age of 65 years (interquartile range [IQR], 48-75 years) were studied. Diverticular disease was the most common benign cause and recto-sigmoid cancer the most common malignancy. Anterior resection and bladder repair were the most frequent operations in benign cases, as was total pelvic exenteration in the malignant group. Multiple intestinal loop involvement and subsequent resection were significantly higher in those with Crohn disease than it was in patients of colovesical fistula due to all other causes collectively (60% vs. 6%, P = 0.006). Patients with malignancy had a higher postoperative complication rate than patients who did not (12 [80%] vs. 7 [32%], P = 0.0005). Pelvic collection (11, 22%) was the most frequent early complication (predominantly in the malignant group) whereas incisional hernia (8, 22%) was the most common late complication, with a predominance in the benign group. The median hospital stay was significantly prolonged in the malignant group (32 days; IQR, 17-70 days vs. 16 days; IQR, 11-25 days; P < 0.001).
  
  
  CONCLUSIONS
  Despite their having similar clinical presentation, colovesical fistulae of various aetiologies differ significantly in management and outcome.
authors.affiliation: Department of Colorectal Surgery, Guy's and St. Thomas' NHS Trust, London, UK.
authors.forename: Qamar Hafeez
authors.initials: QH
authors.lastname: Kiani
authors.affiliation: Department of Colorectal Surgery, Guy's and St. Thomas' NHS Trust, London, UK.
authors.forename: Mark L
authors.initials: ML
authors.lastname: George
authors.affiliation: Department of Colorectal Surgery, Guy's and St. Thomas' NHS Trust, London, UK.
authors.forename: Emin A
authors.initials: EA
authors.lastname: Carapeti
authors.affiliation: Department of Colorectal Surgery, Guy's and St. Thomas' NHS Trust, London, UK.
authors.forename: Alexis M P
authors.initials: AM
authors.lastname: Schizas
authors.affiliation: Department of Colorectal Surgery, Guy's and St. Thomas' NHS Trust, London, UK.
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Williams
keywords: Adenocarcinoma; Colovesical fistula; Diverticulitis; Fistula; Pelvic exenteration