title: Quantitative analysis of marker compounds in Angelica gigas, Angelica sinensis, and Angelica acutiloba by HPLC/DAD.
abstract: Although Danggui is the root of Angelica gigas NAKAI in the Korean Pharmacopoeia, it is determined that Danggui is also the root of Angelica sinensis (OLIV.) DIELS in China and Hong Kong, as well as the root of Angelica acutiloba KITAGAWA in Japan. Accordingly, we tried to develop an identification method using the main compounds in A. gigas, A. sinensis, and A. acutiloba through HPLC/diode-array detector (DAD). This method was fully validated for linearity, accuracy, precision, recovery, and robustness. Multivariate analysis was also implemented after pattern analysis and monitoring. As a result, each compound pattern of A. gigas, A. sinensis, and A. acutiloba was identified, making it possible to distinguish them from each other.
authors.affiliation: Herbal Medicine Research Division, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety.
authors.forename: Su Yang
authors.initials: SY
authors.lastname: Jeong
authors.forename: Hye Mi
authors.initials: HM
authors.lastname: Kim
authors.forename: Kyu Ha
authors.initials: KH
authors.lastname: Lee
authors.forename: Kyu Yeob
authors.initials: KY
authors.lastname: Kim
authors.forename: Dae Sun
authors.initials: DS
authors.lastname: Huang
authors.forename: Jong Hwan
authors.initials: JH
authors.lastname: Kim
authors.forename: Rack Seon
authors.initials: RS
authors.lastname: Seong
mesh_terms: D029969:Angelica / Q000737:chemistry* / Q000378:metabolism; D029971:Angelica sinensis / Q000737:chemistry* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D010936:Plant Extracts / Q000032:analysis* / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry / Q000378:metabolism; D025341:Principal Component Analysis
chemical_list: D010936:Plant Extracts