title: Antibacterial action of doped CoFe2O4 nanocrystals on multidrug resistant bacterial strains.
abstract: The bactericidal effect of pristine and doped cobalt ferrite nanoparticles has been evaluated against multiple drug resistant clinical strains by assessing the number of colony-forming units (CFU). Monophasic polycrystalline ferrites have been prepared by the malate-glycolate sol-gel autocombustion method as confirmed by the X-ray diffraction study. Various changes occurring during the preparative stages have been demonstrated using TG-DTA analysis which is well complemented by the FTIR spectroscopy. The antibacterial studies carried out demonstrate a bactericidal effect of the nanoparticles wherein the number of CFU has been found to decrease with doping. Cellular distortions have been revealed through SEM. Variation in the number of CFU with dopant type has also been reported herein.
authors.affiliation: Department of Biotechnology, St. Xavier's College, Goa, India.
authors.forename: S
authors.initials: S
authors.lastname: Velho-Pereira
authors.affiliation: Department of Biotechnology, St. Xavier's College, Goa, India.
authors.forename: A
authors.initials: A
authors.lastname: Noronha
authors.affiliation: Department of Biotechnology, St. Xavier's College, Goa, India.
authors.forename: A
authors.initials: A
authors.lastname: Mathias
authors.affiliation: Department of Biotechnology, St. Xavier's College, Goa, India.
authors.forename: R
authors.initials: R
authors.lastname: Zakane
authors.affiliation: Department of Biotechnology, St. Xavier's College, Goa, India.
authors.forename: V
authors.initials: V
authors.lastname: Naik
authors.affiliation: Department of Biotechnology, St. Xavier's College, Goa, India.
authors.forename: P
authors.initials: P
authors.lastname: Naik
authors.affiliation: Department of Chemistry, Goa University, Goa, India.
authors.forename: A V
authors.initials: AV
authors.lastname: Salker
authors.affiliation: Department of Chemistry, St. Xavier's College, Goa, India. Electronic address: srnaik19@gmail.com.
authors.forename: S R
authors.initials: SR
authors.lastname: Naik
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D003035:Cobalt / Q000737:chemistry*; D024901:Drug Resistance, Multiple, Bacterial; D005290:Ferric Compounds / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D005290:Ferric Compounds; D003035:Cobalt
keywords: Bactericidal; Cobalt ferrites; Multidrug resistant; Nanoparticles; TEM