title: [The expression and significance of adaptin-2 in mice cochlea].
abstract: OBJECTIVE
  To investigate the expression of adaptin-2(AP-2) in mice cochlea and to discuss the probable role in the endocytosis of hair cells.
  
  
  METHODS
  Laser scanning confocal microscopy and immune-fluroscence histochemistry were performed in this study.
  
  
  RESULTS
  In mature mice cochlea, the immunoreactivity for AP-2 was found in the inner hair cells cytoplasm. This protein mainly expressed in the hair cells basal part and nearby the ribbon synapse.
  
  
  CONCLUSIONS
  AP-2 protein mainly expressed in the hair cells synaptic activity zone , which suggested that AP-2 could play an important role in the synaptic vesicle endocytosis. This finding built the foundation for the further research involved in the physiological and pathological role of AP-2.
authors.forename: Xiang
authors.initials: X
authors.lastname: Gu
authors.forename: Rui
authors.initials: R
authors.lastname: Song
authors.forename: Zhiji
authors.initials: Z
authors.lastname: Chen
authors.forename: Wei
authors.initials: W
authors.lastname: Yuan
mesh_terms: D033965:Adaptor Protein Complex alpha Subunits / Q000378:metabolism*; D000818:Animals; D003051:Cochlea; D006198:Hair Cells, Auditory; D006199:Hair Cells, Auditory, Inner / Q000378:metabolism*; D051379:Mice; D018613:Microscopy, Confocal; D013569:Synapses
chemical_list: D033965:Adaptor Protein Complex alpha Subunits