title: Simulation of Low-Intensity Ultrasound Propagating in a Beagle Dog Dentoalveolar Structure to Investigate the Relations between Ultrasonic Parameters and Cementum Regeneration.
abstract: The therapeutic effect of low-intensity pulsed ultrasound on orthodontically induced inflammatory root resorption is believed to be brought about through mechanical signals induced by the low-intensity pulsed ultrasound. However, the stimulatory mechanism triggering dental cell response has not been clearly identified yet. The aim of this study was to evaluate possible relations between the amounts of new cementum regeneration and ultrasonic parameters such as pressure amplitude and time-averaged energy density. We used the finite-element method to simulate the previously published experiment on ultrasonic wave propagation in the dentoalveolar structure of beagle dogs. Qualitative relations between the thickness of the regenerated cementum in the experiment and the ultrasonic parameters were observed. Our results indicated that the areas of the root surface with greater ultrasonic pressure were associated with larger amounts of cementum regeneration. However, the establishment of reliable quantitative correlations between ultrasound parameters and cementum regeneration requires more experimental data and simulations.
authors.affiliation: Department of Civil & Environmental Engineering, Faculty of Engineering, University of Alberta, Edmonton, Alberta, Canada. Electronic address: vafaeian@ualberta.ca.
authors.forename: Behzad
authors.initials: B
authors.lastname: Vafaeian
authors.affiliation: Department of Orthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia.
authors.forename: Saleh
authors.initials: S
authors.lastname: Al-Daghreer
authors.affiliation: Department of Civil & Environmental Engineering, Faculty of Engineering, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Marwan
authors.initials: M
authors.lastname: El-Rich
authors.affiliation: Department of Civil & Environmental Engineering, Faculty of Engineering, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Samer
authors.initials: S
authors.lastname: Adeeb
authors.affiliation: Department of Dentistry, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Tarek
authors.initials: T
authors.lastname: El-Bialy
mesh_terms: D000818:Animals; D025021:Cementogenesis / Q000502:physiology* / Q000528:radiation effects; D003198:Computer Simulation; D004285:Dogs; D008954:Models, Biological; D011829:Radiation Dosage; D012038:Regeneration / Q000502:physiology* / Q000528:radiation effects; D012542:Scattering, Radiation; D014464:Ultrasonic Therapy / Q000379:methods*; D000069453:Ultrasonic Waves
keywords: Cementum; Dentoalveolar structure; Finite-element method; Root resorption; Ultrasound