title: Worsening heart failure: challenges as a therapeutic target.
authors.affiliation: Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio. Electronic address: tangw@ccf.org.
authors.forename: W H Wilson
authors.initials: WHW
authors.lastname: Tang
authors.affiliation: Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.
authors.forename: Justin L
authors.initials: JL
authors.lastname: Grodin
mesh_terms: D005260:Female; D006333:Heart Failure / Q000175:diagnosis*; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D012065:Relaxin / Q000627:therapeutic use*; D014970:Xanthines / Q000627:therapeutic use*
chemical_list: D014970:Xanthines; D012065:Relaxin
keywords: acute heart failure; clinical endpoint; outcomes; worsening heart failure