title: MRI-guided percutaneous transpedicular biopsy of thoracic and lumbar spine using a 0.23t scanner with optical instrument tracking.
abstract: OBJECTIVE
  To prospectively evaluate the safety and accuracy of magnetic resonance imaging (MRI)-guided percutaneous transpedicular biopsy of thoracic and lumbar spine using 0.23T magnetic resonance imaging with optical tracking.
  
  
  METHODS
  Sixty-seven thoracic and lumbar spine lesions in 67 patients underwent MRI-guided percutaneous transpedicular biopsy using 0.23T MRI with optical tracking. These lesions were divided into two groups according to the location: 16 lesions in the thoracic spine and 51 lesions in the lumbar spine. The diagnostic accuracy, sensitivity, and specificity were calculated, and comparison of the two groups was performed using Fisher's exact test. Each patient was monitored for complications.
  
  
  RESULTS
  All specimens obtained were sufficient for diagnosis. Histological examination of MRI-guided percutaneous biopsy revealed 38 malignant and 29 benign lesions. The final diagnoses from surgery or clinical follow-up were 42 malignant lesions and 25 benign lesions. The combined diagnostic performance of MRI-guided percutaneous transpedicular thoracic and lumbar biopsy in diagnosing malignant tumors was as follows: accuracy, 94%; sensitivity, 89%; and specificity, 100%. There was no significant difference between the two groups (P = 1, Fisher's exact test). No serious complications occurred.
  
  
  CONCLUSIONS
  MRI-guided percutaneous transpedicular biopsy is a safe and accurate diagnostic technique to evaluate thoracic and lumbar spine lesions.
authors.affiliation: Department of Interventional MRI, Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong, P.R. China.
authors.forename: Ming
authors.initials: M
authors.lastname: Liu
authors.affiliation: South Western Finland Imaging Centre, Turku University Hospital, Turku, Finland.
authors.forename: Roberto Blanco
authors.initials: RB
authors.lastname: Sequeiros
authors.affiliation: Department of Interventional MRI, Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong, P.R. China.
authors.forename: Yujun
authors.initials: Y
authors.lastname: Xu
authors.affiliation: Department of Interventional MRI, Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong, P.R. China.
authors.forename: Xiangmeng
authors.initials: X
authors.lastname: He
authors.affiliation: Department of hepatobiliary and pancreatic surgery, First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang, P.R. China.
authors.forename: Tongyin
authors.initials: T
authors.lastname: Zhu
authors.affiliation: Department of Interventional Radiology, Qingdao Central Hospital, Qingdao, Shandong, P.R. China.
authors.forename: Lei
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Interventional MRI, Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong, P.R. China.
authors.forename: Yubo
authors.initials: Y
authors.lastname: Lü
authors.affiliation: Department of Interventional MRI, Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong, P.R. China.
authors.forename: Jie
authors.initials: J
authors.lastname: Huang
authors.affiliation: Department of Interventional MRI, Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong, P.R. China.
authors.forename: Chengli
authors.initials: C
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation; D061705:Image-Guided Biopsy / Q000295:instrumentation*; D008159:Lumbar Vertebrae / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008875:Middle Aged; D009339:Needles; D055096:Optical Devices; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013122:Spinal Diseases / Q000473:pathology*; D013904:Thoracic Vertebrae / Q000473:pathology*; D055815:Young Adult
keywords: biopsy; guidance; interventional radiology; magnetic resonance; spine