title: Low-grade serous primary peritoneal carcinoma incidentally found in a hernia sac.
abstract: Very rarely, a primary peritoneal serous carcinoma can be observed in a hernia sac. We herein describe a low-grade serous primary peritoneal carcinoma incidentally found in a postmenopausal woman following examination of the femoral hernia repair sac. Our case is significant for its unusual presentation. The lesion initially appeared as a 0.3-cm tumor that disseminated in the peritoneum, persisted, and progressed for 75 months. The absence of ovarian disease indicated a primary peritoneal origin. Tumor cells were immunohistochemically positive for PAX8, claudin-4, and VE1, excluding the possibility of being of mesothelial origin. Recognition that a low-grade serous primary peritoneal carcinoma can be incidentally found in a hernia sac should simplify future diagnoses. Immunohistochemistry is helpful in making the correct diagnosis.
authors.affiliation: Anatomical Pathology Department, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria and IDIVAL, Santander, Spain. Electronic address: apavbj@humv.es.
authors.forename: José-Fernando
authors.initials: JF
authors.lastname: Val-Bernal
authors.affiliation: Anatomical Pathology Department, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria and IDIVAL, Santander, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Mayorga
authors.affiliation: Laboratoire National de Santé, Division d́Anatomie Pathologique, Dudelange, Luxembourg.
authors.forename: Daniel
authors.initials: D
authors.lastname: Val
authors.affiliation: Anatomical Pathology Department, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria and IDIVAL, Santander, Spain.
authors.forename: María-Francisca
authors.initials: MF
authors.lastname: Garijo
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D018284:Cystadenocarcinoma, Serous / Q000150:complications / Q000473:pathology*; D005260:Female; D006550:Hernia, Femoral / Q000150:complications*; D006801:Humans; D007150:Immunohistochemistry; D033162:Incidental Findings; D008875:Middle Aged; D060787:Neoplasm Grading; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D010534:Peritoneal Neoplasms / Q000150:complications / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: Hernia sac; Immunohistochemistry; Peritoneum; Primary peritoneal low-grade serous carcinoma