title: Postoperative cystoid macular oedema in a patient on fingolimod.
abstract: We describe the first case of fingolimod-associated bilateral cystoid macular oedema (CMO) following uncomplicated cataract surgery. A 57-year-old woman has been on fingolimod for the past 2 years for the treatment of relapsing-remitting multiple sclerosis. She underwent uneventful consecutive cataract surgery 2 weeks apart. Three weeks following the second cataract operation, she reported gradual-onset blurred vision bilaterally. Examination revealed mildly reduced visual acuity and bilateral CMO. Treatment with topical corticosteroids and non-steroidal anti-inflammatory eye drops, as well as cessation of fingolimod in collaboration with the neurologist, resulted in complete resolution of the CMO. Patients on fingolimod are likely to be at increased risk of developing postoperative CMO.
authors.affiliation: Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.
authors.forename: Jennifer Chen-Chia Fan
authors.initials: JC
authors.lastname: Gaskin
authors.affiliation: Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.
authors.forename: Michael
authors.initials: M
authors.lastname: Coote
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002387:Cataract Extraction / Q000009:adverse effects*; D004008:Diclofenac / Q000627:therapeutic use; D005260:Female; D000068876:Fingolimod Hydrochloride / Q000009:adverse effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008269:Macular Edema / Q000188:drug therapy / Q000209:etiology*; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000188:drug therapy; D009883:Ophthalmic Solutions; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D009883:Ophthalmic Solutions; D004008:Diclofenac; C009935:prednisolone acetate; D011239:Prednisolone; D000068876:Fingolimod Hydrochloride