title: Non-V delta 2 gamma delta T lymphocytes as effectors of cancer immunotherapy.
abstract: Gamma delta T cells (γδT) are potent mediators of antitumor cytotoxicity and have shown promising efficacy in early phase clinical trials. Most is known about the tumoricidal properties of cells bearing the Vδ2 T cell receptor chain, but recent studies have demonstrated that cells with the Vδ1 chain and those with neither Vδ1 nor Vδ2 chains have properties which may make them more attractive anticancer effectors in adoptive immunotherapy.
authors.affiliation: Section of Cancer; UCL Institute of Child Health ; London, UK.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Fisher
authors.affiliation: Section of Molecular and Cellular Immunology; UCL Institute of Child Health ; London, UK.
authors.forename: Anne-Marijn
authors.initials: AM
authors.lastname: Kramer
authors.affiliation: Section of Molecular and Cellular Immunology; UCL Institute of Child Health ; London, UK.
authors.forename: Kenth
authors.initials: K
authors.lastname: Gustafsson
authors.affiliation: Section of Cancer; UCL Institute of Child Health ; London, UK.
authors.forename: John
authors.initials: J
authors.lastname: Anderson
keywords: Vdelta-1; gamma-delta T cell; neuroblastoma; ovarian cancer; preclinical