title: Radiation-associated Cardiac Injury.
abstract: Chest radiotherapy continues to play an important role in the treatment of breast cancer, Hodgkin's lymphoma, and other malignancies. Subsequent cardiac injury has been described involving essentially all structures of the heart, with most radiation-induced injury being progressive in nature. Our understanding over the multifactorial etiology and development of radiation-associated cardiac injury has advanced, leading to improved techniques aimed at decreasing cardiac radiation exposure and associated risks. Monitoring after radiotherapy clearly appears to be indicated; however, optimal recommendations regarding cardiac screening remain difficult to establish.
authors.affiliation: St. Mary's Medical Center, San Francisco, CA, U.S.A.
authors.forename: Robert
authors.initials: R
authors.lastname: Eldabaje
authors.affiliation: St. Mary's Medical Center, San Francisco, CA, U.S.A.
authors.forename: Duong L
authors.initials: DL
authors.lastname: Le
authors.affiliation: Warren Alpert Medical School, Brown University, Providence, RI, U.S.A.
authors.forename: Wendy
authors.initials: W
authors.lastname: Huang
authors.affiliation: St. Mary's Medical Center, San Francisco, CA, U.S.A. Radiobiology Laboratory, California Pacific Medical Center Research Institute, San Francisco, CA, U.S.A. yangl@cpmcri.org.
authors.forename: Li-Xi
authors.initials: LX
authors.lastname: Yang
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy; D002318:Cardiovascular Diseases / Q000473:pathology*; D005260:Female; D006335:Heart Injuries / Q000473:pathology*; D006689:Hodgkin Disease / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D011832:Radiation Injuries / Q000473:pathology*; D011878:Radiotherapy / Q000009:adverse effects*; D012307:Risk Factors
keywords: Chest radiotherapy; cardiac injury; radiation; review