title: Changes in Markers of Ovarian Reserve After Laparoscopic Ovarian Cystectomy.
abstract: OBJECTIVE
  This study was conducted to determine the changes in ovarian reserve markers after laparoscopic ovarian cystectomy (LOC).
  
  
  METHODS
  Prospective cohort study (Canadian Task Force classification II-2).
  
  
  METHODS
  University teaching hospital.
  
  
  METHODS
  Fifty 50 patients who underwent LOC were prospectively examined to determine the changes in serum markers of ovarian reserve, starting from 1 month before and 3 months after consecutive operations.
  
  
  METHODS
  Changes in serum markers were compared between the following groups: endometrioma cysts (n = 26) versus nonendometrioma cysts (n = 24), unilateral cystectomy (n = 38) versus bilateral cystectomy (n = 12), and bilateral endometrioma extirpation (n = 10) versus other cystectomy operations (n = 40).
  
  
  RESULTS
  A significant change was noticed between the preoperative and postoperative antimüllerian hormone (AMH) levels (2.67 ± 2.67 ng/mL vs 1.84 ± 1.72 ng/mL, p < .0001). Serum AMH levels were found to be significantly decreased in endometrioma (p = .002), nonendometrioma (p = .019), unilateral cystectomy (p = .001), bilateral cystectomy (p = .005), bilateral endometrioma (p = .011), and cysts other than bilateral endometrioma (p = .000) groups.
  
  
  CONCLUSIONS
  The ovarian reserve was found to be diminished after LOC regardless of the presence of endometrioma that could be distinguishable by serum AMH levels.
authors.affiliation: Department of Obstetrics and Gynecology, Istanbul University Istanbul School of Medicine, Istanbul, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Ergun
authors.affiliation: Department of Obstetrics and Gynecology, Istanbul University Istanbul School of Medicine, Istanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ozsurmeli
authors.affiliation: Department of Obstetrics and Gynecology, GATA Haydarpasa Military Education Hospital, Istanbul, Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Dundar
authors.affiliation: Department of Obstetrics and Gynecology, Istanbul University Istanbul School of Medicine, Istanbul, Turkey.
authors.forename: Cihan
authors.initials: C
authors.lastname: Comba
authors.affiliation: Department of Obstetrics and Gynecology, Istanbul University Istanbul School of Medicine, Istanbul, Turkey.
authors.forename: Oguzhan
authors.initials: O
authors.lastname: Kuru
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, Gulhane Military Medical Academy, Ankara, Turkey. Electronic address: serkan_bodur@yahoo.com.
authors.forename: Serkan
authors.initials: S
authors.lastname: Bodur
mesh_terms: D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D003560:Cysts / Q000601:surgery*; D004715:Endometriosis / Q000097:blood / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects*; D008875:Middle Aged; D010048:Ovarian Cysts / Q000097:blood / Q000601:surgery*; D065851:Ovarian Reserve; D010052:Ovariectomy / Q000009:adverse effects*; D011184:Postoperative Period; D011446:Prospective Studies
chemical_list: D015415:Biomarkers; D054304:Anti-Mullerian Hormone
keywords: Antimüllerian hormone; Estradiol; Follicle-stimulating hormone; Laparoscopic ovarian cystectomy; Ovarian reserve