title: Potential of the chemical dinotefuran in the control of Rhipicephalus sanguineus (Latreille, 1806) (Acari: Ixodidae) semi-engorged female ticks.
abstract: Ticks are vectors of several pathogens to vertebrates, including the human being. They produce lesions on the hosts during the blood feeding and great economic losses. Several chemical acaricides have been used in an attempt to control tick infestations; however these substances are harmful to both the human being and non-target organisms, and to the environment. Therefore, there is a need to fight these ectoparasites through less harmful methods, less aggressive to the environment, non-target organisms and to the human health. The present study examined the efficacy of dinotefuran on the susceptibility of Rhipicephalus sanguineus semi-engorged females exposed to different concentrations of the product. Its lethal concentration of 50% (LC50) at 95% confidence interval was determined. The ticks were immersed in Petri dishes containing different concentrations of dinotefuran or distilled water for 5 minutes and then dried and maintained in an incubator for 7 days. The results showed the daily number of dead R. sanguineus semi-engorged females after being treated with different concentrations of dinotefuran. The mortality data in bioassay 2 were subjected to Probit analysis, where a LC50 of 10,182.253 ppm (8725.987-13,440.084) and 95% confidence interval were estimated. The susceptibility of R. sanguineus semi-engorged females to dinotefuran in higher concentrations of the acaricide was demonstrated, indicating that its effect is probably dose-dependent. In addition, the action of dinotefuran was slow and gradual, interfering in the development and growth of the individuals throughout the observation period (7 days).
authors.affiliation: Department of Biology, Institute of Biosciences, São Paulo State University-UNESP, Av. 24 A, n° 1515, 199, 13506-900, Rio Claro, SP, Brazil. Electronic address: patyrosaoliv@yahoo.com.br.
authors.forename: Patrícia Rosa
authors.initials: PR
authors.lastname: de Oliveira
authors.affiliation: Department of Ecology, Institute of Biosciences, São Paulo State University-UNESP, Av. 24 A, n° 1515, 199, 13506-900, Rio Claro, SP, Brazil.
authors.forename: Marcos Aparecido
authors.initials: MA
authors.lastname: Pizano
authors.affiliation: Department of Biology, Institute of Biosciences, São Paulo State University-UNESP, Av. 24 A, n° 1515, 199, 13506-900, Rio Claro, SP, Brazil.
authors.forename: Rafael Neodini
authors.initials: RN
authors.lastname: Remédio
authors.affiliation: Department of Animal Pathology, Faculty of Agronomic and Veterinary Sciences, São Paulo State University-UNESP, Via de Acesso Prof. Paulo Castellane, s/n, 14884-900, Jaboticabal, SP, Brazil.
authors.forename: Gervásio Henrique
authors.initials: GH
authors.lastname: Bechara
authors.affiliation: Center for Biological Sciences and Nature (CCBN), UFAC, Distrito Industrial, 69917-400, Rio Branco, AC, Brazil.
authors.forename: Rusleyd Maria Magalhães
authors.initials: RM
authors.lastname: de Abreu
authors.affiliation: Department of Biology, Institute of Biosciences, São Paulo State University-UNESP, Av. 24 A, n° 1515, 199, 13506-900, Rio Claro, SP, Brazil.
authors.forename: Maria Izabel
authors.initials: MI
authors.lastname: Camargo Mathias
mesh_terms: D056810:Acaricides; D000818:Animals; D001096:Arachnid Vectors; D001681:Biological Assay; D004305:Dose-Response Relationship, Drug; D005260:Female; D006146:Guanidines; D006801:Humans; D007928:Lethal Dose 50; D000073943:Neonicotinoids; D009574:Nitro Compounds; D011817:Rabbits; D048508:Rhipicephalus sanguineus; D013983:Tick Control
chemical_list: D056810:Acaricides; D006146:Guanidines; D000073943:Neonicotinoids; D009574:Nitro Compounds; C465368:dinotefuran
keywords: Acaricide; Dinotefuran; Neonicotinoids; Rhipicephalus sanguineus; Tick