title: Chondrosarcoma of the larynx: report of two cases and review of the literature.
abstract: Primary chondroid tumors of the larynx represent less than 1% of all laryngeal tumors. Most of them are chondromas and they often involve to the cricoid cartilage. They are characterized by a low tendency to metastatic diffusion (low grade). The treatment of choice is surgery, which may be endoscopic or "open partial surgery", if extension of the cancer is limited. Prognosis is generally good. In this report, two cases of low grade chondrosarcoma of the larynx are presented, one was treated surgically with cricoidectomy and partial laryngectomy, and another was treated surgically with hemicricoidectomy. Laryngoscopy reveals tumefaction of the larynx, covered by intact mucosa. Computerized tomography imaging with contrast and magnetic resonance imaging defines not only coarse calcifications, pathognomonic of chondromatous neoformations but also the relationship of the neoformation with the surrounding tissues. Treatment is essentially surgical, given the importance of preserving the larynx to patients' quality of life, the only risk is recurrence, which is treated by a second surgery.
authors.affiliation: Department of Otolaryngology, First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou 310003, PR China.
authors.forename: Qinying
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Otolaryngology, First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou 310003, PR China.
authors.forename: Haihong
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of Otolaryngology, First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou 310003, PR China.
authors.forename: Shuihong
authors.initials: S
authors.lastname: Zhou
mesh_terms: D000328:Adult; D002813:Chondrosarcoma / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D016896:Treatment Outcome
keywords: Chondrosarcoma; laryngectomy; larynx