title: Aggressive Digital Papillary Adenocarcinoma: Case Report of a Positive Sentinel Lymph Node and Discussion of Utility of Sentinel Lymph Node Biopsy.
abstract: Aggressive digital papillary adenocarcinoma (ADPA) is an uncommon eccrine sweat gland tumor of the distal extremities that is associated with a high rate of local recurrence and distant metastasis. Current opinion suggests that sentinel lymph node evaluation should be done for high-risk tumors where lymph node spread is a concern. Despite documented spread to regional lymph nodes, information on sentinel lymph node status in ADPA is reported infrequently, with only 1 documented case of positive findings. We report on a case of ADPA of the right long finger where sentinel lymph node biopsy was done and positive for metastases in the axilla, resulting in a subsequent completion lymphadenectomy. To determine the benefit of sentinel lymph node biopsy in ADPA, there is a need for more cases of sentinel lymph node evaluation along with data on local recurrence and distant metastasis in those with positive and negative findings.
authors.affiliation: From the Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Wisconsin Hospital and Clinics, Madison, WI.
authors.forename: Steve J
authors.initials: SJ
authors.lastname: Kempton
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Navarrete
authors.forename: A Neil
authors.initials: AN
authors.lastname: Salyapongse
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000473:pathology*; D005385:Fingers; D006801:Humans; D008297:Male; D008875:Middle Aged; D021701:Sentinel Lymph Node Biopsy; D013544:Sweat Gland Neoplasms / Q000473:pathology*