title: Nephrotic syndrome associated with immune thrombocytopenia revealing Kimura's disease in a non-Asian male.
abstract: We report the case of a young Caucasian man presenting with diffuse oedema and nephrotic syndrome. Clinical examination revealed multiple lymphadenopathies. Histological examination was consistent with the diagnosis of Kimura's disease. A renal biopsy showed focal segmental glomerulosclerosis. Immune thrombocytopenia and signs of humoral autoimmunity were discovered. Corticosteroid treatment induced remission of nephrotic syndrome but relapses occurred 12 and 18 months after onset of treatment while the patient was receiving 20 mg prednisone once a day. To our knowledge, this is the first case of Kimura's disease and nephrotic syndrome associated with B-cell autoreactivity.
authors.affiliation: Department of Nephrology, AP-HP , Hôpital Tenon , F-75020.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Noel
authors.affiliation: Department of Pathology, AP-HP , Hôpital Saint-Louis , Paris.
authors.forename: Véronique
authors.initials: V
authors.lastname: Meignin
authors.affiliation: Department of Internal Medicine , Hôpital de Coulommiers , Coulommiers , France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Rosenstingl
authors.affiliation: Department of Nephrology, AP-HP , Hôpital Tenon , F-75020.
authors.forename: Pierre
authors.initials: P
authors.lastname: Ronco
authors.affiliation: Department of Nephrology, AP-HP , Hôpital Tenon , F-75020.
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Boffa
keywords: Kimura’s disease; immune thrombocytopenia; nephrotic syndrome