title: Immunohistochemical and lectin histochemical studies on the developing olfactory organs of fetal camel.
abstract: Little is known about the development of the olfactory organs of camel. In this study, prenatal development and neuronal differentiation of the vomeronasal organ (VNO) and the olfactory epithelium (OE) of the one-humped camel were studied by immunohistochemistry and lectin histochemistry. A neuronal marker, protein gene product (PGP) 9.5, but not a marker of fully differentiated olfactory receptor cells, olfactory marker protein, intensely labeled the olfactory receptor cells of the VNO and OE at 395 mm, 510 mm, and 530 mm fetal ages, indicating that the olfactory receptor cells are differentiated, but not fully matured both in the VNO and the OE. In 187 mm and 190 mm fetuses, PGP 9.5 yielded faint immunoreactive signals in the VNO, but not in the OE, although the presence of olfactory receptor cells were demonstrated in both tissues by intense WGA and LEL stainings. We conclude that the camel VNO and OE bear differentiated, but still immature receptor cells; in addition, the onset of neuronal differentiation seems to be somewhat earlier in the VNO than in the OE till half of the prenatal life.
authors.affiliation: United Graduate School of Veterinary Sciences, Gifu University, Gifu, 501-1193, Japan.|Department of Histology, Faculty of Veterinary Medicine, South Valley University, Qena, 83523, Egypt.
authors.forename: Dalia
authors.initials: D
authors.lastname: Ibrahim
authors.affiliation: Laboratory of Veterinary Anatomy, School of Veterinary Medicine, Kitasato University, Towada, Aomori, 034-8628, Japan.
authors.forename: Kazumi
authors.initials: K
authors.lastname: Taniguchi
authors.affiliation: United Graduate School of Veterinary Sciences, Gifu University, Gifu, 501-1193, Japan.|Laboratory of Veterinary Anatomy, Faculty of Agriculture, Iwate University, Morioka, Iwate, 020-8550, Japan.
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Yamamoto
authors.affiliation: Emeritus Professor, Faculty of Agriculture, Iwate University, Morioka, Iwate, 020-8550, Japan.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Taniguchi
authors.affiliation: United Graduate School of Veterinary Sciences, Gifu University, Gifu, 501-1193, Japan.|Laboratory of Veterinary Anatomy, Faculty of Agriculture, Iwate University, Morioka, Iwate, 020-8550, Japan.
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Nakamuta
mesh_terms: D000818:Animals; D002162:Camelus / Q000196:embryology* / Q000378:metabolism; D002454:Cell Differentiation; D005260:Female; D007150:Immunohistochemistry; D037102:Lectins / Q000032:analysis / Q000378:metabolism*; D008297:Male; D009831:Olfactory Mucosa / Q000737:chemistry / Q000196:embryology / Q000378:metabolism; D018034:Olfactory Receptor Neurons / Q000737:chemistry / Q000166:cytology / Q000378:metabolism; D038081:Organogenesis; D019147:Vomeronasal Organ / Q000737:chemistry* / Q000196:embryology* / Q000378:metabolism
chemical_list: D037102:Lectins
keywords: OMP; PGP 9.5; fetus; olfactory epithelium; vomeronasal organ