title: [Metabolic adaptation resources of organism to studying at medical university students in European North].
abstract: BACKGROUND
  A student studying is accompanied with psychoemotional stress that requires functional changes in metabolic systems. A blood leucocytes enzyme activity indexes that provides an adaptation are the indicators of energy metabolism.
  
  
  OBJECTIVE
  The aim of investigation is to determine the features and role of metabolic adaptive changes in the white blood cells of the students in European North during educational process.
  
  
  METHODS
  In the course of year, third course general practitioner faculty students of medical university were investigated seven times (before and after autumn semester, after winter examination period, after summer examination time and during a summer vacation). In blood leucocytes of all the examined patients indicators of enzymes activity of dehydrogenases were detected - succinate dehydrogenase (SDG) and glutamate dehydrogenase (GDG), as well as hydrolytic enzymes - acid phosphatase and alkaline phosphatase.
  
  
  RESULTS
  During the year different changes of blood leucocytes enzyme activity were detected depending on the intensity of training load; a most higher SDG and GDG activity were detected in winter time, after examination period as well as after spring semester; an acid phosphatase occurred in the autumn semester but alkaline phosphatase increased in all examination times.
  
  
  CONCLUSIONS
  An enzyme activity changes have a phase character and are accompanied by a coherent, mutual interaction that depends on educational process specifics and examinations. This changes lead to adequacy of adaptation response.
authors.forename: S N
authors.initials: SN
authors.lastname: Ignatyeva
authors.forename: R V
authors.initials: RV
authors.lastname: Koubassov
mesh_terms: D000222:Adaptation, Physiological; D004734:Energy Metabolism; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008297:Male; D010088:Oxidoreductases / Q000097:blood; D010744:Phosphoric Monoester Hydrolases / Q000097:blood; D012426:Russia; D012577:Schools, Medical; D012621:Seasons; D013315:Stress, Psychological / Q000201:enzymology*; D013334:Students; D055815:Young Adult
chemical_list: D010088:Oxidoreductases; D010744:Phosphoric Monoester Hydrolases