title: Egg consumption and risk of type 2 diabetes among African Americans: The Jackson Heart Study.
abstract: Type 2 diabetes (DM) disproportionally affects African Americans. Data on the association between egg consumption and risk of DM are sparse. We sought to examine whether egg consumption is associated with the prevalence and incidence of DM among African Americans.
  
  
  
  We analyzed baseline data from 4568 participants of the Jackson Heart Study. Egg consumption was obtained using a food frequency questionnaire designed for this population. We used generalized estimating equations to calculate adjusted prevalence ratios of DM and Cox regression to estimate hazard ratios of DM with corresponding 95% confidence intervals (CI).
  
  
  
  The average age was 55 ± 13 years and 64% of subjects were women. The median frequency of egg consumption was 2/week for men and 1/week for women. The prevalence of DM was 22% overall (21% of men and 23% of women). Multivariable adjusted prevalence ratio [PR (95% CI)] for DM were: 1.00 (ref), 1.14 (0.90-1.44), 1.33 (1.04-1.70), 1.33 (1.06-1.68), 1.26 (0.99-1.61), and 1.52 (1.17-1.97) for egg consumption of <1/month, 1-3/month, 1/week, 2/week, 3-4/week, and 5+/week, respectively, p for linear trend 0.0024. Corresponding multivariable adjusted hazard ratios were 1.00 (ref), 0.88 (0.65-1.19), 0.94 (0.68-1.30), 0.91 (0.66-1.25), 1.11 (0.81-1.52), and 1.17 (0.81-1.70), respectively, during a mean follow up of 7.3 years (p for linear trend 0.22).
  
  
  
  While egg consumption was positively associated with prevalent DM, prospective analysis did not show an association of egg intake with incidence of DM among African Americans.
authors.affiliation: Brigham and Women's Hospital, Boston, MA, USA; Boston Veterans Affairs Healthcare System, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: Ldjousse@rics.bwh.harvard.edu.
authors.forename: Luc
authors.initials: L
authors.lastname: Djoussé
authors.affiliation: Brigham and Women's Hospital, Boston, MA, USA.
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Petrone
authors.affiliation: University of Mississippi Medical Center, Jackson, MS, USA; My Brother's Keeper, Inc, Ridgeland, MS, USA.
authors.forename: DeMarc A
authors.initials: DA
authors.lastname: Hickson
authors.affiliation: Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
authors.forename: Sameera A
authors.initials: SA
authors.lastname: Talegawkar
authors.affiliation: South Central VA MIRECC and Little Rock GRECC, Little Rock, AR, USA.
authors.forename: Patricia M
authors.initials: PM
authors.lastname: Dubbert
authors.affiliation: Morehouse School of Medicine, Atlanta, GA, USA.
authors.forename: Herman
authors.initials: H
authors.lastname: Taylor
authors.affiliation: University of Massachusetts Lowell, Lowell, MA, USA.
authors.forename: Katherine L
authors.initials: KL
authors.lastname: Tucker
mesh_terms: D000328:Adult; D001741:Black or African American; D000368:Aged; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology / Q000208:ethnology / Q000209:etiology* / Q000517:prevention & control; D000072001:Diet, Healthy / Q000208:ethnology; D004531:Eggs / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D008922:Mississippi / Q000453:epidemiology; D010349:Patient Compliance / Q000208:ethnology; D015995:Prevalence; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012307:Risk Factors; D057566:Self Report; D012737:Sex Factors
keywords: Eggs; Epidemiology; Nutrition; Risk factors; Type 2 diabetes