title: Synthesis of alkynes from vinyl triflates using tetrabutylammonium fluoride.
abstract: A convenient method for the preparation of alkynes and alkynyl esters from ketones and β-keto esters is described which involves the formation of vinyl triflates, followed by elimination with tetrabutylammonium fluoride trihydrate, to give alkynes. Unlike established elimination methods, the method requires neither a strong base nor anhydrous conditions.
authors.affiliation: Faculty of Pharmacy, Meijo University.
authors.forename: Masaru
authors.initials: M
authors.lastname: Okutani
authors.forename: Yuji
authors.initials: Y
authors.lastname: Mori
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D000480:Alkynes; D008698:Mesylates; D000644:Quaternary Ammonium Compounds; D014753:Vinyl Compounds; C437735:vinyl triflate; C009405:tetrabutylammonium