title: Anterior Chamber Angle and Intraocular Pressure Changes After Phacoemulsification: A Comparison Between Eyes With Closed-angle and Open-angle Glaucoma.
abstract: OBJECTIVE
  To compare the angle and intraocular pressure (IOP) changes after phacoemulsification between eyes with closed-angle or open-angle glaucoma.
  
  
  METHODS
  Angle measurements using Visante AS-OCT imaging was performed for a prospective cohort of 24 subjects with closed-angle and 30 subjects with open-angle glaucoma before and 3 months after phacoemulsification. IOP measurement was measured at 6 and 12 months after surgery using Goldmann applanation tonometry as secondary outcome measures.
  
  
  RESULTS
  Eyes with closed angles were smaller than those with open angles (mean axial length 22.88 vs. 24.11 mm, P<0.001). Mean anterior chamber depth, area, volume, AOD500, AOD750, ARA, TISA500, and TISA750 increased after phacoemulsification in all eyes regardless of preexisting angle status (all P<0.001). Increase in AOD500, AOD750, TISA500, and TISA750 were greater in eyes with open angles compared with closed angles (P=0.03, 0.04. 0.04, 0.04, respectively). Mean IOP decreased by 1.8 and 2.1 mm Hg at 6 and 12 months, respectively, after phacoemulsification for all eyes (P<0.001 for both timepoints compared with preoperative baseline). However, postoperative reduction in the mean IOP was not significantly different between eyes with closed and open angles (Mann-Whitney test P=0.32 at 6 mo and P=0.75 at 12 mo postsurgery compared with preoperative).
  
  
  CONCLUSIONS
  Angle opening postphacoemulsification was considerable in all eyes. A similar IOP reduction after phacoemulsification was observed in all eyes regardless of angle status.
authors.affiliation: Singapore National Eye Centre, Singapore Eye Research Institute, Singapore, Singapore.
authors.forename: Jay
authors.initials: J
authors.lastname: Siak
authors.forename: Desmond
authors.initials: D
authors.lastname: Quek
authors.forename: Monisha E
authors.initials: ME
authors.lastname: Nongpiur
authors.forename: Sue-Wei
authors.initials: SW
authors.lastname: Ho
authors.forename: Hla M
authors.initials: HM
authors.lastname: Htoon
authors.forename: Shamira
authors.initials: S
authors.lastname: Perera
authors.forename: Tin
authors.initials: T
authors.lastname: Aung
authors.forename: Tina
authors.initials: T
authors.lastname: Wong
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000473:pathology; D044466:Asian People / Q000208:ethnology; D003315:Cornea / Q000473:pathology*; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000208:ethnology / Q000503:physiopathology*; D005902:Glaucoma, Open-Angle / Q000208:ethnology / Q000503:physiopathology*; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D007498:Iris / Q000473:pathology*; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011184:Postoperative Period; D011446:Prospective Studies; D012846:Singapore / Q000453:epidemiology; D041623:Tomography, Optical Coherence; D014065:Tonometry, Ocular; D058609:Visual Field Tests