title: Hairy math: addition of Wnt-3a to multiply bulge cells.
abstract: Canonical Wnt signals are important for activation of epithelial skin stem cells, but the role of individual Wnt ligands remains uncertain. Ouji et al. demonstrate a key role for Wnt-3a in partial maintenance and long-term expansion of epithelial skin stem cells in vitro. They also report a method for expanding these cells in vitro without feeder cells.
authors.affiliation: Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors.forename: M
authors.initials: M
authors.lastname: Zulfiquer Hossain
authors.affiliation: Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address: LAG@jhmi.edu.
authors.forename: Luis A
authors.initials: LA
authors.lastname: Garza
mesh_terms: D000818:Animals; D004847:Epithelial Cells / Q000166:cytology*; D005260:Female; D013234:Stem Cells / Q000166:cytology*; D060509:Wnt3A Protein / Q000494:pharmacology*
chemical_list: D060509:Wnt3A Protein