title: 6-year-old boy with recurrent sinopulmonary infections and lymphadenopathy.
authors.affiliation: Department of Medicine, Division of Allergy, Asthma and Immunology, University of Virginia, Charlottesville, Va.
authors.forename: Monica G
authors.initials: MG
authors.lastname: Lawrence
authors.affiliation: Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Md. Electronic address: guzel@niaid.nih.gov.
authors.forename: Gulbu
authors.initials: G
authors.lastname: Uzel
mesh_terms: D015415:Biomarkers / Q000097:blood; D002648:Child; D002908:Chronic Disease; D058534:Class I Phosphatidylinositol 3-Kinases / Q000235:genetics*; D003586:Cytomegalovirus Infections / Q000097:blood / Q000175:diagnosis / Q000201:enzymology / Q000235:genetics* / Q000276:immunology; D004252:DNA Mutational Analysis; D020031:Epstein-Barr Virus Infections / Q000097:blood / Q000175:diagnosis / Q000201:enzymology / Q000235:genetics* / Q000276:immunology; D020022:Genetic Predisposition to Disease; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D008206:Lymphatic Diseases / Q000097:blood / Q000175:diagnosis / Q000201:enzymology / Q000235:genetics* / Q000276:immunology; D008297:Male; D009154:Mutation; D010641:Phenotype; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000097:blood / Q000175:diagnosis / Q000201:enzymology / Q000235:genetics* / Q000276:immunology; D013577:Syndrome
chemical_list: D015415:Biomarkers; D007136:Immunoglobulins; D058534:Class I Phosphatidylinositol 3-Kinases; C486018:PIK3CD protein, human
keywords: Activated p110δ; Cytomegalovirus (CMV); Epstein-Barr virus (EBV); Hyper-IgM syndrome; Nodular lymphoid hyperplasia