title: A facile and mild synthesis of trisubstituted allylic sulfones from Morita-Baylis-Hillman carbonates.
abstract: An efficient and catalyst-free synthesis of trisubstituted allylic sulfones through an allylic sulfonylation reaction of Morita-Baylis-Hillman (MBH) carbonates with sodium sulfinates has been developed. Under the optimized reaction conditions, a series of trisubstituted allylic sulfones were rapidly prepared in good to excellent yields (71%-99%) with good to high selectivity (Z/E from 79:21 to >99:1). Compared with known synthetic methods, the current protocol features mild reaction temperature, high efficiency and easily available reagents.
authors.affiliation: Engineering Research Center of Biopolymer Functional Materials of Yunnan, School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. jianglin_1981@163.com.|Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. jianglin_1981@163.com.
authors.forename: Lin
authors.initials: L
authors.lastname: Jiang
authors.affiliation: Engineering Research Center of Biopolymer Functional Materials of Yunnan, School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. lyg1990wsh@163.com.
authors.forename: Yong-Gen
authors.initials: YG
authors.lastname: Li
authors.affiliation: Engineering Research Center of Biopolymer Functional Materials of Yunnan, School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. zjf109lq@163.com.
authors.forename: Jiang-Feng
authors.initials: JF
authors.lastname: Zhou
authors.affiliation: Engineering Research Center of Biopolymer Functional Materials of Yunnan, School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. chuan5211017@126.com.|Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. chuan5211017@126.com.
authors.forename: Yong-Ming
authors.initials: YM
authors.lastname: Chuan
authors.affiliation: Engineering Research Center of Biopolymer Functional Materials of Yunnan, School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. honglili_1982@163.com.|Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. honglili_1982@163.com.
authors.forename: Hong-Li
authors.initials: HL
authors.lastname: Li
authors.affiliation: Engineering Research Center of Biopolymer Functional Materials of Yunnan, School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. yml@vip.163.com.|Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, School of Chemistry and Biotechnology, Yunnan Minzu University, Kunming 650500, China. yml@vip.163.com.
authors.forename: Ming-Long
authors.initials: ML
authors.lastname: Yuan
mesh_terms: D000498:Allyl Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D002254:Carbonates / Q000737:chemistry*; D002384:Catalysis; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry*; D013696:Temperature
chemical_list: D000498:Allyl Compounds; D002254:Carbonates; D013450:Sulfones