title: Evaluation of high sensitive troponin in erectile dysfunction.
abstract: BACKGROUND
  Evidence is accumulating in favour of a link between erectile dysfunction (ED) and coronary artery diseases. We investigated the presence of cardiac injury in patients who have had arteriogenic and nonarteriogenic ED using the hs-Tn levels.
  
  
  METHODS
  The diagnosis of ED was based on the International Index of Erectile Function 5-questionnaire (IIF-5) and patients were classified as arteriogenic (A-ED, n = 40), nonarteriogenic (NA-ED, n = 48), and borderline (BL-ED, n = 32) patients in relation to the results of echo-color-Doppler examination of cavernous arteries. The level of hs-TnT and hs-TnI was measured in 120 men with a history of ED of less than one year with no clinical evidence of cardiac ischemic disease.
  
  
  RESULTS
  The levels of both hs-TnT and hs-TnI were within the reference range and there was no significant (P > 0.05) difference between patients of the three groups. The hs-CRP values were higher in A-ED men compared with NA-ED (P = 0.048) but not compared with BL-ED (P = 0.136) and negatively correlated with IIF-5 (r = -0.480; P = 0.031).
  
  
  CONCLUSIONS
  In ED patients of the three groups the measurement of hs-Tn allows us to exclude the presence of cardiac involvement at least when the history of ED is less than one year and the men are without atherosclerotic risk factors.
authors.affiliation: Laboratorio di Analisi, Ospedale San Paolo, Dipartimento di Scienze della Salute, Università degli Studi di Milano, 20142 Milano, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Barassi
authors.affiliation: Dipartimento di Malattie dell'Apparato Digerente e Medicina Interna, Ospedale Sant'Orsola-Malpighi, Alma Mater Studiorum, Università degli Studi di Bologna, 40138 Bologna, Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Pezzilli
authors.affiliation: Dipartimento di Malattie dell'Apparato Digerente e Medicina Interna, Ospedale Sant'Orsola-Malpighi, Alma Mater Studiorum, Università degli Studi di Bologna, 40138 Bologna, Italy.
authors.forename: Antonio Maria
authors.initials: AM
authors.lastname: Morselli-Labate
authors.affiliation: Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, 20133 Milano, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Dozio
authors.affiliation: Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche, Università di Milano, 20133 Milano, Italy.
authors.forename: Luca
authors.identifier: 0000-0002-2690-7095
authors.initials: L
authors.lastname: Massaccesi
authors.affiliation: Laboratorio di Analisi, Ospedale San Paolo, Dipartimento di Scienze della Salute, Università degli Studi di Milano, 20142 Milano, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Ghilardi
authors.affiliation: Laboratorio di Analisi, Ospedale San Paolo, Dipartimento di Scienze della Salute, Università degli Studi di Milano, 20142 Milano, Italy.
authors.forename: Clara Anna Linda
authors.initials: CA
authors.lastname: Damele
authors.affiliation: Istituto per la Sterilità e la Sessualità (ISES), 20123 Milano, Italy.
authors.forename: Giovanni Maria
authors.initials: GM
authors.lastname: Colpi
authors.affiliation: Laboratorio di Analisi, Ospedale San Paolo, Dipartimento di Scienze della Salute, Università degli Studi di Milano, 20142 Milano, Italy.
authors.forename: Gian Vico Melzi
authors.initials: GV
authors.lastname: d'Eril
authors.affiliation: Dipartimento di Scienze Biomediche per la Salute, Università degli Studi di Milano, 20133 Milano, Italy ; Unità Operativa Medicina di Laboratorio-1 Patologia Clinica, IRCCS Policlinico San Donato, San Donato Milanese, 20097 Milano, Italy.
authors.forename: Massimiliano Marco
authors.initials: MM
authors.lastname: Corsi Romanelli
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D003324:Coronary Artery Disease / Q000097:blood / Q000150:complications*; D007172:Erectile Dysfunction / Q000097:blood* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019210:Troponin I / Q000097:blood*; D020107:Troponin T / Q000097:blood*
chemical_list: D015415:Biomarkers; D019210:Troponin I; D020107:Troponin T