title: Malignant fibrous histiocytoma of the skull base: A neurosurgical nuance.
abstract: A 69-year-old male, treated for colonic carcinoma 15 years back, presented to our services with status epilepticus. He had complaints of headache and vomiting for 7 days prior to presentation. Computed tomography and magnetic resonance imaging of the brain revealed heterogeneous, lobulated and osteolytic tumor involving middle and posterior cranial fossa. Excision of the tumor was planned in two stages. Middle fossa component was removed through right temporobasal approach. Histopathology was suggestive of malignant fibrous histiocytoma. Patient succumbed to pneumonia and septicemia in the postoperative period. Pathology, clinical features and therapeutic challenges of this clinical entity have been briefly reviewed.
authors.affiliation: Department of Neurosurgery, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Parel, Mumbai, Maharashtra, India.
authors.forename: Amit
authors.initials: A
authors.lastname: Mahore
authors.affiliation: Department of Neurosurgery, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Parel, Mumbai, Maharashtra, India.
authors.forename: Raghvendra
authors.initials: R
authors.lastname: Ramdasi
authors.affiliation: Department of Neurosurgery, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Parel, Mumbai, Maharashtra, India.
authors.forename: Nitin
authors.initials: N
authors.lastname: Dange
authors.affiliation: Department of Neuropathology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
authors.forename: Sridhar
authors.initials: S
authors.lastname: Epari
keywords: Skull base; calvarial sarcoma; malignant fibrous histiocytoma; metastasis; undifferentiated pleomorphic soft tissue sarcoma