title: Regulation of redox signalling and autophagy during cardiovascular diseases-role of resveratrol.
abstract: Cardiovascular diseases remain one of the major health problems worldwide. The worldwide research against cardio-vascular diseases as well as genome wide association studies were successful in indentifying the loci associated with these prominent life threatening diseases but still a substantial amount of casualty remains unexplained. Over the last decade, the thorough understanding of molecular and biochemical mechanisms of cardiac disorders lead to the knowledge of various mechanisms of action of polyphenols to target inflammation during cardiac disorders. The present review article is focused on role of phytochemical resveratrol in regulation of redox signalling, autophagy and inflammation during cardiovascular pathology.
authors.affiliation: Department of Cardiology, Xiangyang Hospital Affiliated to Hubei University of Medicine, Xiangyang, Hubei, P.R. China. contribution083@163.com.
authors.forename: D-G
authors.initials: DG
authors.lastname: Fu
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology / Q000627:therapeutic use*; D001343:Autophagy / Q000187:drug effects* / Q000502:physiology; D002318:Cardiovascular Diseases / Q000188:drug therapy* / Q000378:metabolism*; D006801:Humans; D010084:Oxidation-Reduction / Q000187:drug effects; D000077185:Resveratrol; D013267:Stilbenes / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000975:Antioxidants; D013267:Stilbenes; D000077185:Resveratrol