title: A comparative study of contrast enhanced ultrasound and contrast enhanced magnetic resonance imaging for the detection and characterization of hepatic hemangiomas.
abstract: This study aims to compare contrast enhanced ultrasound (CEUS) and contrast enhanced magnetic resonance imaging (CEMRI) for the detection and characterization of hepatic hemangiomas. Included in this retrospective study were 83 histopathologically confirmed lesions of hemangioma in 66 hospitalized patients who underwent both CEUS and CEMRI and received surgery. The enhancement patterns on CEUS and CEMRI in each lesion were compared and analyzed. In addition, data obtained by the two modalities were then compared with the pathological findings to determine their value in differential diagnosis of hepatic hemangiomas. CEUS diagnosed 78 lesions of hemangioma against 80 by CEMRI. There were no statistical significant differences in the diagnostic value between CEUS and CEMRI in terms of sensitivity (88.0% vs. 92.8%), specificity (99.0% vs. 99.4%), accuracy (97.3% vs. 98.4%), positive predictive value (93.6% vs. 96.3%), and negative predictive value (98.0% vs. 98.8%) (p > 0.05, all). In the arterial phase, the main enhancement pattern on both CEUS and CEMRI was peripheral nodular enhancement (73 vs. 76), but lesions with diffuse enhancement on CEUS outnumbered those on CEMRI (3 vs. 1) and lesions with circular enhancement on CEMRI outnumbered those on CEUS (3 vs. 2). In the portal venous phase and delayed phase, the main enhancement pattern was hyperechoic change on CEUS and hyperintense on CEMRI (66 vs. 65), some lesions presented isoechoic change (12 vs. 15). These results suggested CEUS, an equivalent to CEMRI, may have an added diagnostic value in hemangiomas.
authors.affiliation: Department of Ultrasound, Zhongshan Hospital, Fudan University.
authors.forename: Liang
authors.initials: L
authors.lastname: Fang
authors.forename: Zheng
authors.initials: Z
authors.lastname: Zhu
authors.forename: Beijian
authors.initials: B
authors.lastname: Huang
authors.forename: Hong
authors.initials: H
authors.lastname: Ding
authors.forename: Feng
authors.initials: F
authors.lastname: Mao
authors.forename: Chaolun
authors.initials: C
authors.lastname: Li
authors.forename: Mengsu
authors.initials: M
authors.lastname: Zeng
authors.forename: Jianjun
authors.initials: J
authors.lastname: Zhou
authors.forename: Ling
authors.initials: L
authors.lastname: Wang
authors.forename: Wenping
authors.initials: W
authors.lastname: Wang
authors.forename: Yue
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D006391:Hemangioma / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014465:Ultrasonics; D014463:Ultrasonography
chemical_list: D003287:Contrast Media