title: Cell signaling in the interaction between pathogenic bacteria and immune cells.
abstract: Cell signaling is an essential part in the complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is essential for cell survival and basic biological function. In the defense from pathogenic bacteria, the immune cells exert their function through various signaling pathways. In this review, we will summarize recent findings on the role of cell signaling in the interaction between pathogenic bacteria and immune cells, focusing on neutrophils and macrophages, which are part of the innate immunity, and also T cells, which are components of the adaptive immune system.
authors.affiliation: School of Life Sciences, Northwestern Polytechnical University, 710072 Xi'an, China, 2Key Laboratory for Space Bioscience and Biotechnology, Northwestern Polytechnical University, 710072 Xi'an, China, kittyyh@sina.cn.
authors.forename: Hui
authors.initials: H
authors.lastname: Yang
authors.forename: Yaxiong
authors.initials: Y
authors.lastname: Liu
authors.forename: Ruihua
authors.initials: R
authors.lastname: Tang
authors.forename: Dongyan
authors.initials: D
authors.lastname: Shao
authors.affiliation: Department of Pharmacology, New York Medical College, Valhalla, New York 10595.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Ji
authors.initials: J
authors.lastname: Li
authors.forename: Linjie
authors.initials: L
authors.lastname: Ye
authors.forename: Mingliang
authors.initials: M
authors.lastname: Jin
authors.forename: Qingsheng
authors.initials: Q
authors.lastname: Huang
authors.forename: Junling
authors.initials: J
authors.lastname: Shi
mesh_terms: D001419:Bacteria / Q000276:immunology*; D060833:Cellular Microenvironment; D006801:Humans; D008264:Macrophages / Q000378:metabolism / Q000502:physiology*; D018448:Models, Immunological; D009504:Neutrophils / Q000378:metabolism / Q000502:physiology*; D016897:Respiratory Burst; D015398:Signal Transduction