title: Impact of libido at 2 weeks after stroke on risk of stroke recurrence at 1-year in a chinese stroke cohort study.
abstract: BACKGROUND
  There were few studies on the relation between changes in libido and incidence of stroke recurrence. The aim of this study was to investigate the relationship between libido decrease at 2 weeks after stroke and recurrent stroke at 1-year.
  
  
  METHODS
  It is a multi-centered, prospective cohort study. The 14 th item of the Hamilton Depression Rating Scale-17 was used to evaluate changes of libido in poststroke patients at 2 weeks. Stroke recurrence was defined as an aggravation of former neurological functional deficit, new local or overall symptoms, or stroke diagnosed at re-admission.
  
  
  RESULTS
  Among 2341 enrolled patients, 1757 patients had completed follow-up data, 533 (30.34%) patients had decreased libido at 2 weeks, and 166 (9.45%) patients had recurrent stroke at 1-year. Multivariate logistic regression analysis showed that, compared with patients with normal libido, the odds ratio (OR) of recurrent stroke in patients with decreased libido was reduced by 41% (OR = 0.59, 95% confidence interval [CI]: 0.40-0.87). The correlation was more prominent among male patients (OR = 0.52, 95% CI: 0.31-0.85) and patients of ≥60 years of age (OR = 0.57, 95% CI: 0.35-0.93).
  
  
  CONCLUSIONS
  One out of three stroke patients in mainland China has decreased libido at 2 weeks after stroke. Decreased libido is a protective factor for stroke recurrence at 1-year, which is more prominent among older male patients.
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Li
authors.forename: Huai-Wu
authors.initials: HW
authors.lastname: Yuan
authors.affiliation: Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Institute for Brain Disorders, Beijing Key Laboratory of Translational Medicine for Cerebrovascular Disease; Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Chun-Xue
authors.initials: CX
authors.lastname: Wang
authors.forename: Ben-Yan
authors.initials: BY
authors.lastname: Luo
authors.forename: Jie
authors.initials: J
authors.lastname: Ruan
authors.forename: Ning
authors.initials: N
authors.lastname: Zhang
authors.forename: Yu-Zhi
authors.initials: YZ
authors.lastname: Shi
authors.forename: Yong
authors.initials: Y
authors.lastname: Zhou
authors.forename: Yi-Long
authors.initials: YL
authors.lastname: Wang
authors.forename: Tong
authors.initials: T
authors.lastname: Zhang
authors.forename: Juan
authors.initials: J
authors.lastname: Zhou
authors.forename: Xing-Quan
authors.initials: XQ
authors.lastname: Zhao
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Wang
mesh_terms: D000368:Aged; D044466:Asian People; D002681:China; D005260:Female; D006801:Humans; D015994:Incidence; D007989:Libido / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology*