title: Gut microbes, immunity, and spondyloarthritis.
abstract: The last decade has witnessed an explosion of studies evaluating the impact of the human microbiota on a variety of disease states. The microbiota can impact diseases in multiple ways, including through abnormalities in the diversity and contents of the microbiota, as well as by acting as targets of immunologic dysregulation. Herein, evidence that the microbiota in spondyloarthritis is both altered and abnormally targeted by the immune system will be presented.
authors.affiliation: University of Alabama at Birmingham, CPP N 210 M, 1600 7th Avenue South, Birmingham, AL 35233-1711, USA. Electronic address: mstoll@peds.uab.edu.
authors.forename: Matthew L
authors.initials: ML
authors.lastname: Stoll
mesh_terms: D000818:Animals; D001171:Arthritis, Juvenile / Q000276:immunology / Q000382:microbiology; D015535:Arthritis, Psoriatic / Q000276:immunology / Q000382:microbiology; D016918:Arthritis, Reactive / Q000276:immunology / Q000382:microbiology; D000069196:Gastrointestinal Microbiome / Q000276:immunology*; D006801:Humans; D007107:Immune System / Q000276:immunology; D007249:Inflammation; D015212:Inflammatory Bowel Diseases / Q000276:immunology* / Q000382:microbiology; D007422:Intestines / Q000276:immunology* / Q000382:microbiology; D051379:Mice; D025242:Spondylarthropathies / Q000276:immunology* / Q000382:microbiology; D013167:Spondylitis, Ankylosing / Q000276:immunology / Q000382:microbiology
keywords: Inflammatory bowel disease; Microbiome; Microbiota; Spondyloarthritis