title: Post-transplant lymphoproliferative disorder: case report and review of susceptibility to EBV in the Scottish adult renal transplant pool.
abstract: We report a case of high-grade non-Hodgkin's lymphoma following Epstein-Barr virus (EBV) infection in a 38-year-old renal transplant recipient who was successfully treated with rituximab and remains alive 6 years later with reasonable graft function. We subsequently undertook a survey showing that 1.8% of the Scottish adult transplant pool are susceptible to EBV infection. Though a vaccine for EBV is currently not yet available, routine screening of potential renal transplant recipients for EBV should help identify those at increased risk of post-transplant lymhoproliferative disorder (PTLD), while tailoring of immunosuppression and antiviral prophylaxis with Ganciclovir may help reduce the emergence of this potentially life-threatening disease.
authors.affiliation: Department of Renal Medicine, Dumfries and Galloway Royal Infirmary, Dumfries DG1 4AP.
authors.forename: Viknesh
authors.initials: V
authors.lastname: Selvarajah
authors.affiliation: Department of Renal Medicine, Dumfries and Galloway Royal Infirmary, Dumfries DG1 4AP.
authors.forename: Katie
authors.initials: K
authors.lastname: Lake
authors.affiliation: Department of Renal Medicine, Dumfries and Galloway Royal Infirmary, Dumfries DG1 4AP.
authors.forename: Sue
authors.initials: S
authors.lastname: Robertson
authors.affiliation: West of Scotland Specialist Virology Laboratory , Gartnavel General Hospital , Glasgow G12 0ZA , UK.
authors.forename: William
authors.initials: W
authors.lastname: Carman
authors.affiliation: Department of Renal Medicine, Dumfries and Galloway Royal Infirmary, Dumfries DG1 4AP.
authors.forename: Chris
authors.initials: C
authors.lastname: Isles
keywords: CMV; EBV; PTLD; renal; transplantation