title: Oral Rehabilitation of Adult Edentulous Siblings Severely Lacking Alveolar Bone Due to Ectodermal Dysplasia: A Report of 2 Clinical Cases and a Literature Review.
abstract: The oral conditions of adult edentulous patients with ectodermal dysplasia (ED) often lead to decreased physical and psychological health, and the negative effects can become as extreme as social and psychological isolation. However, restoring oral function of adult edentulous patients with ED using zygomatic implants (ZIs) or conventional implants (CIs) remains challenging for dentists because of the severe atrophy of these patients' alveolar ridges. This report describes 2 cases of adult edentulous siblings with ED; they exhibited severe alveolar bone atrophy and were treated with ZIs and CIs as bases to augment the bone in their anterior jaws. For these patients, bone augmentation was completed with an autogenous fibular graft. Although there was mild evidence of bone graft resorption in the maxilla, the bone augmentation procedures were successful in the 2 patients. Effective osseointegration of the implants was obtained. After placement, the functional and esthetic results of the oral rehabilitation were acceptable. More importantly, restoration of the patients' oral function enhanced their self-confidence and self-esteem. Therefore, restoring oral function in adult patients with ED and edentulous jaws using ZIs and CIs as the bases for bone augmentation is an effective approach.
authors.affiliation: Professor, Department of Oral Implant, School of Medicine, Ninth People's Hospital Affiliated with Shanghai Jiao Tong University, Shanghai, China. Electronic address: yiqunwu@hotmail.com.
authors.forename: Yiqun
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, School of Medicine, Ninth People's Hospital Affiliated with Shanghai Jiao Tong University, Shanghai, China.
authors.forename: Chenping
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Assistant Professor, Laboratory of Epithelial Biology, Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI.
authors.forename: Cristiane H
authors.initials: CH
authors.lastname: Squarize
authors.affiliation: Associate Professor, Department of Dental Implant Center, Stomatological Hospital and College, Anhui Medical University, Key Laboratory of Oral Diseases Research of Anhui Province, Hefei, China. Electronic address: zouduohongyy@126.com.
authors.forename: Duohong
authors.initials: D
authors.lastname: Zou
mesh_terms: D000328:Adult; D000539:Alveolar Process / Q000473:pathology*; D003758:Dental Implantation, Endosseous; D004476:Ectodermal Dysplasia / Q000473:pathology*; D006801:Humans; D009066:Mouth, Edentulous / Q000534:rehabilitation*; D035781:Siblings; D055815:Young Adult