title: Intelligence measures and stage 2 sleep in typically-developing and autistic children.
abstract: The relationship between intelligence measures and 2 EEG measures of non-rapid eye movement sleep, sleep spindles and Sigma activity, was examined in 13 typically-developing (TD) and 13 autistic children with normal IQ and no complaints of poor sleep. Sleep spindles and Sigma EEG activity were computed for frontal (Fp1, Fp2) and central (C3, C4) recording sites. Time in stage 2 sleep and IQ was similar in both groups. Autistic children presented less spindles at Fp2 compared to the TD children. TD children showed negative correlation between verbal IQ and sleep spindle density at Fp2. In the autistic group, verbal and full-scale IQ scores correlated negatively with C3 sleep spindle density. The duration of sleep spindles at Fp1 was shorter in the autistic group than in the TD children. The duration of sleep spindles at C4 was positively correlated with verbal IQ only in the TD group. Fast Sigma EEG activity (13.25-15.75 Hz) was lower at C3 and C4 in autistic children compared to the TD children, particularly in the latter part of the night. Only the TD group showed positive correlation between performance IQ and latter part of the night fast Sigma activity at C4. These results are consistent with a relationship between EEG activity during sleep and cognitive processing in children. The difference between TD and autistic children could derive from dissimilar cortical organization and information processing in these 2 groups.
authors.affiliation: Sleep Laboratory & Clinic, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Centre de Recherche, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Centre de Recherche, Institut Universitaire en Santé Mentale de Montréal, Montréal, Québec, Canada.
authors.forename: Sophie
authors.initials: S
authors.lastname: Tessier
authors.affiliation: Sleep Laboratory & Clinic, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Centre de Recherche, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Centre de Recherche, Institut Universitaire en Santé Mentale de Montréal, Montréal, Québec, Canada.
authors.forename: Andréane
authors.initials: A
authors.lastname: Lambert
authors.affiliation: Sleep Laboratory & Clinic, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Centre de Recherche, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Centre de Recherche, Institut Universitaire en Santé Mentale de Montréal, Montréal, Québec, Canada.
authors.forename: Marjolaine
authors.initials: M
authors.lastname: Chicoine
authors.affiliation: Department of Psychology, Université du Québec à Montréal, Montréal, Québec, Canada.
authors.forename: Peter
authors.initials: P
authors.lastname: Scherzer
authors.affiliation: Department of Psychology, Université du Québec à Montréal, Montréal, Québec, Canada; Autism Clinic, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Centre de Recherche, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Centre de Recherche, Institut Universitaire en Santé Mentale de Montréal, Montréal, Québec, Canada.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Soulières
authors.affiliation: Sleep Laboratory & Clinic, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Department of Psychiatry, Université de Montréal, Montréal, Québec, Canada; Autism Clinic, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Centre de Recherche, Hôpital Rivière-des-Prairies, Montréal, Québec, Canada; Centre de Recherche, Institut Universitaire en Santé Mentale de Montréal, Montréal, Québec, Canada. Electronic address: roger.godbout@umontreal.ca.
authors.forename: Roger
authors.initials: R
authors.lastname: Godbout
mesh_terms: D000293:Adolescent; D001321:Autistic Disorder / Q000503:physiopathology*; D058256:Brain Waves / Q000502:physiology*; D002540:Cerebral Cortex / Q000503:physiopathology*; D002648:Child; D002657:Child Development / Q000502:physiology; D004569:Electroencephalography; D006801:Humans; D007360:Intelligence / Q000502:physiology*; D008297:Male; D017397:Prefrontal Cortex / Q000503:physiopathology; D012894:Sleep Stages / Q000502:physiology*
keywords: Autism; Children; EEG; IQ; Non-REM sleep