title: Simultaneous suppression of tone burst-evoked otoacoustic emissions: Two and three-tone burst combinations.
abstract: Previous investigations have shown that components of a tone burst-evoked otoacoustic emission (TBOAE) evoked by a 1 kHz tone burst (TB1) can be suppressed by the simultaneous presence of a 2 kHz tone burst (TB2) or a pair of tone bursts at 2 and 3 kHz (TB2 and TB3 respectively). No previous study has measured this "simultaneous suppression of TBOAEs" for both TB2 alone and TB2 and TB3 from the same ears, so that the effect of the additional presence of TB3 on suppression caused by TB2 is not known. In simple terms, three outcomes are possible; suppression increases, suppression is reduced or suppression is not affected. Comparison of previously reported simultaneous suppression data suggests TB3 causes a reduction in suppression, though it is not clear if this is a genuine effect or simply reflects methodological and ear differences between studies. This issue has implications for previously proposed mechanisms of simultaneous suppression of TBOAEs and the interpretation of clinical data, and is clarified by the present study. Simultaneous suppression of TBOAEs was measured for TB1 and TB2 as well as TB1, TB2 and TB3 at 50, 60 and 70 dB p.e. SPL from nine normal human ears. Results showed no significant difference between mean suppression obtained for the two and three-tone burst combinations, indicating the reduction of suppression inferred from comparison of previous data is likely a result of methodological and ear differences rather than a genuine effect.
authors.affiliation: Faculty of Medicine and Health, University of Leeds, UK. Electronic address: e.killan@leeds.ac.uk.
authors.forename: Edward C
authors.initials: EC
authors.lastname: Killan
authors.affiliation: Institute of Sound and Vibration Research, University of Southampton, UK.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Lutman
authors.affiliation: Faculty of Medicine and Health, University of Leeds, UK.
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Thyer
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods*; D000293:Adolescent; D000328:Adult; D001299:Audiometry; D001306:Auditory Pathways / Q000502:physiology*; D003051:Cochlea / Q000294:innervation*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D009433:Neural Inhibition; D009622:Noise / Q000009:adverse effects*; D017084:Otoacoustic Emissions, Spontaneous; D010470:Perceptual Masking; D013018:Sound Spectrography; D055815:Young Adult