title: Effect of EDTA conditioning on cervical restorations bonded with a self-etch adhesive: A randomized double-blind clinical trial.
abstract: OBJECTIVE
  To compare the 18-month retention rates of composite restorations in non-carious cervical lesions [NCCLs] bonded with a self-etch adhesive with and without preliminary conditioning with EDTA.
  
  
  METHODS
  Forty-eight patients with two similar-sized NCCL were selected and randomly allocated to one of two groups. Two calibrated operators placed 96 restorations with a one-step self-etch adhesive (Adper Easy One, 3M ESPE). Half of the restorations were placed according to the manufacturer's instructions while, for the other half, the surfaces of the lesions were conditioned with 17% EDTA for 2 min prior to adhesive application. Two blinded and independent examiners evaluated the restorations at baseline, 6, 12, and 18 months, according to the FDI criteria. The comparison between groups in each period was conducted with the Fisher's exact test, and the performance of each group at the different periods was evaluated by McNemar's test (α=0.05).
  
  
  RESULTS
  After 18 months, significantly higher retention rates (95% CI) were observed for the EDTA group (95.5 [84.9-98.7]) than the control group (79.6% [65.5-88.9]) (p=0.02). Significant deterioration of the marginal adaptation and marginal discoloration were observed for both groups over the 18-month evaluation.
  
  
  CONCLUSIONS
  The preliminary conditioning with EDTA before application of a one-step self-etch adhesive significantly improved the retention rates of composite restorations in cervical lesions.
  
  
  CONCLUSIONS
  Conditioning with EDTA is an alternative that improves the 18-month retention rate of cervical restorations bonded with a self-etch adhesive.
authors.affiliation: Faculty of Dentistry, University of Valparaiso, Calle Subida Carvallo, 211, Playa Ancha, Valparaiso CEP 2360004, Chile.
authors.forename: Issis
authors.initials: I
authors.lastname: Luque-Martinez
authors.affiliation: Faculty of Dentistry, University of Valparaiso, Calle Subida Carvallo, 211, Playa Ancha, Valparaiso CEP 2360004, Chile.
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Muñoz
authors.affiliation: School of Dentistry, Department of Restorative Dentistry, Universidad de las Americas, Av. de los Granados E12-41y Colimes esq., Quito EC170125, Ecuador.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Mena-Serrano
authors.affiliation: Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, 4748, Uvaranas, Ponta Grossa, Paraná CEP 84030-900, Brazil.
authors.forename: Viviane
authors.initials: V
authors.lastname: Hass
authors.affiliation: Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, 4748, Uvaranas, Ponta Grossa, Paraná CEP 84030-900, Brazil.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Reis
authors.affiliation: Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Rua Carlos Cavalcanti, 4748, Uvaranas, Ponta Grossa, Paraná CEP 84030-900, Brazil. Electronic address: aloguercio@hotmail.com.
authors.forename: Alessandro D
authors.initials: AD
authors.lastname: Loguercio
mesh_terms: D000180:Acrylic Resins / Q000627:therapeutic use*; D000328:Adult; D017438:Bisphenol A-Glycidyl Methacrylate / Q000627:therapeutic use*; D003188:Composite Resins / Q000627:therapeutic use*; D003738:Dental Cements / Q000627:therapeutic use*; D019232:Dental Restoration Failure; D003793:Dental Restoration, Permanent / Q000009:adverse effects / Q000379:methods*; D004311:Double-Blind Method; D004492:Edetic Acid / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011140:Polyurethanes / Q000627:therapeutic use*; D019279:Resin Cements / Q000627:therapeutic use*; D013997:Time Factors; D014076:Tooth Diseases / Q000628:therapy; D055815:Young Adult
chemical_list: D000180:Acrylic Resins; C000612360:Adper Easy One; C029012:Composite Dental Resin; D003188:Composite Resins; D003738:Dental Cements; D011140:Polyurethanes; D019279:Resin Cements; D017438:Bisphenol A-Glycidyl Methacrylate; D004492:Edetic Acid
keywords: Adhesive; Clinical trial; EDTA; Non-carious cervical lesion; Retention rate