title: Collapsing glomerulopathy after hepatitis C pegylated interferon treatment. Recovery of renal function with high-dose steroid treatment.
abstract: A patient who developed oliguric acute renal failure and nephrotic syndrome within 2 weeks after finishing interferon and ribavirin treatment is reported. At presentation, HCV PCR was negative, and no immunological laboratory test was found altered. A renal biopsy showed collapsing glomerulopathy, and the patient received supportive haemodialysis and high-dose steroids. Twelve days after steroid treatment, renal function started to recover. After 18 weeks, normal renal function and protein/creatinine urinary ratio were achieved and remained normal up to 1-year post-treatment.
authors.affiliation: Division of Nephrology , Hospital Mãe de Deus , Porto Alegre, RS , Brazil.
authors.forename: Roberto H
authors.initials: RH
authors.lastname: Berdichevski
authors.affiliation: Division of Nephrology , Hospital Mãe de Deus , Porto Alegre, RS , Brazil.
authors.forename: Eduardo M
authors.initials: EM
authors.lastname: De Carvalho
authors.affiliation: Division of Pathology , Hospital de Clínicas de Porto Alegre , RS , Brazil.
authors.forename: Maria Isabel
authors.initials: MI
authors.lastname: Edelweiss
authors.affiliation: Division of Nephrology , Hospital Mãe de Deus , Porto Alegre, RS , Brazil.
authors.forename: Luiz Felipe
authors.initials: LF
authors.lastname: Gonçalves
authors.affiliation: Division of Nephrology , Hospital Mãe de Deus , Porto Alegre, RS , Brazil.
authors.forename: Roberto C
authors.initials: RC
authors.lastname: Manfro
keywords: acute renal failure; collapsing glomerulopathy; interferon; nephrotic syndrome