title: Brainstem evoked potential in newly diagnosed patients of subclinical hypothyroidism.
abstract: BACKGROUND
  Hypothyroidism is known to be associated with impairment of hearing. The hearing impairment may be conductive, sensorineural, or mixed.
  
  
  OBJECTIVE
  The aim is to assess the auditory pathway by brainstem auditory evoked potentials (BAEPs) in newly diagnosed patients of subclinical hypothyroidism and healthy sex- and age-matched controls.
  
  
  METHODS
  The study included 25 healthy sex- and age-matched controls (Group I) and 25 patients of newly diagnosed subclinical hypothyroidism (Group II). The recording was taken by using RMS EMG EP MK2 equipment. The unpaired Student's t-test was used and a P value <0.05 was considered significant.
  
  
  RESULTS
  Wave V of right ear BAEP in group II was prolonged (6 ± 0.62 ms) compared to group I (5.49 ± 0.26 ms), and wave V of left ear BAEP in group II was prolonged (5.84 ± 0.57 ms) compared to group I (5.47 ± 0.35 ms). There was no significant coefficient of correlation between wave V and inter-peak latency (IPL) I-V compared to thyroid-stimulating hormone (TSH) levels of both the ears.
  
  
  CONCLUSIONS
  The prolongation of wave V in BAEPs of both ears suggests that the central auditory pathway is affected significantly in subclinical hypothyroid patients.
authors.affiliation: Department of Physiology, Shaheed Hasan Khan Mewati (SHKM) Government Medical College, Nalhar, Uttarkhand, India.
authors.forename: Kirti
authors.initials: K
authors.lastname: Sharma
authors.affiliation: Department of Physiology, Government Medical College (GMC), Srinagar, Pauri Garhwal, India.
authors.forename: Joshil Kumar
authors.initials: JK
authors.lastname: Behera
authors.affiliation: Department of Physiology, Shaheed Hasan Khan Mewati (SHKM) Government Medical College, Nalhar, Uttarkhand, India.
authors.forename: Naresh
authors.initials: N
authors.lastname: Kumar
authors.affiliation: Department of Physiology, Post Graduate Institute of Medical Sciences (PGIMS), Rohtak, Haryana, India.
authors.forename: Sushma
authors.initials: S
authors.lastname: Sood
authors.affiliation: Department of Orthopedics, Shaheed Hasan Khan Mewati (SHKM) Government Medical College, Nalhar, Uttarkhand, India.
authors.forename: Harnam Singh
authors.initials: HS
authors.lastname: Madan
authors.affiliation: Department of Physiology, Shaheed Hasan Khan Mewati (SHKM) Government Medical College, Nalhar, Uttarkhand, India.
authors.forename: Sibadatta
authors.initials: S
authors.lastname: Das
keywords: Brainstem auditory evoked potential (BAEP); hearing impairment; subclinical hypothyroidism