title: SDS-MoS2 nanoparticles as highly-efficient peroxidase mimetics for colorimetric detection of H2O2 and glucose.
abstract: In this work, we find that the peroxidase-like activity of MoS2 nanoparticles (NPs) is dependent on the surface charge. Negatively charged sodium dodecyl sulfate modified MoS2 nanoparticles (SDS-MoS2 NPs) possess highly-efficient peroxidase-like activity. MoS2 NPs with intrinsic peroxidase-like activity were synthesized through a simple one-pot hydrothermal route. The peroxidase-like activities of different surfactants modified MoS2 NPs were discussed. Compared with bare MoS2 NPs and positively charged cetyltrimethyl ammonium bromide modified MoS2 NPs, SDS-MoS2 NPs have the best peroxidase-like activity. SDS-MoS2 NPs can efficiently catalyze the oxidation of 3,3,5,5-tetramethylbenzidine (TMB) in the presence of H2O2 to generate a blue product. On basis of this, we have successfully established a novel platform for colorimetric detection of H2O2, and the detection limit is 0.32μM. Furthermore, the SDS-MoS2 NPs based platform can also be used for high sensitivity and selectivity detection of glucose with a wide linear range of 5.0-500μM by controlling the generation of H2O2 in the presence of glucose oxidase.
authors.affiliation: Department of Chemistry, East China Normal University, Shanghai 200242, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Zhao
authors.affiliation: Department of Chemistry, East China Normal University, Shanghai 200242, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Gu
authors.affiliation: Department of Chemistry, East China Normal University, Shanghai 200242, China.
authors.forename: Sisi
authors.initials: S
authors.lastname: Zheng
authors.affiliation: Department of Chemistry, East China Normal University, Shanghai 200242, China. Electronic address: clzhang@chem.ecnu.edu.cn.
authors.forename: Cuiling
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Department of Chemistry, East China Normal University, Shanghai 200242, China. Electronic address: yzxian@chem.ecnu.edu.cn.
authors.forename: Yuezhong
authors.initials: Y
authors.lastname: Xian
mesh_terms: D001560:Benzidines / Q000737:chemistry; D040761:Biomimetic Materials / Q000737:chemistry*; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods; D001786:Blood Glucose / Q000032:analysis; D003124:Colorimetry / Q000379:methods*; D004220:Disulfides / Q000737:chemistry*; D005947:Glucose / Q000032:analysis*; D006801:Humans; D006861:Hydrogen Peroxide / Q000032:analysis*; D007700:Kinetics; D057230:Limit of Detection; D046529:Microscopy, Electron, Transmission; D008982:Molybdenum / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry* / Q000378:metabolism; D010084:Oxidation-Reduction; D009195:Peroxidase / Q000378:metabolism*; D012967:Sodium Dodecyl Sulfate / Q000737:chemistry
chemical_list: D001560:Benzidines; D001786:Blood Glucose; D004220:Disulfides; D012967:Sodium Dodecyl Sulfate; C021758:3,3',5,5'-tetramethylbenzidine; D008982:Molybdenum; D006861:Hydrogen Peroxide; D009195:Peroxidase; D005947:Glucose; C082964:molybdenum disulfide
keywords: Colorimetric detection; Glucose; Hydrogen peroxide; Molybdenum disulfide; Peroxidase mimetics; Surfactant