title: Updates on management of anoxic brain injury after cardiac arrest.
abstract: Brain injury is a leading cause of mortality and morbidity among cardiac arrest survivors. Management of these patients in the acute phase is challenging as is predicting their outcomes especially with the application of hypothermia. Therapeutic hypothermia has been proven beneficial but target temperature, timing, and duration that produce the best outcome are unclear and the subject of ongoing research. We review the recent advances in therapy and update the guidelines for management of these patients.
authors.forename: Joanna Isabelle
authors.initials: JI
authors.lastname: Ramiro
authors.forename: Abhay
authors.initials: A
authors.lastname: Kumar
mesh_terms: D016887:Cardiopulmonary Resuscitation / Q000009:adverse effects / Q000379:methods; D003422:Critical Care; D006323:Heart Arrest / Q000150:complications* / Q000628:therapy; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods; D002534:Hypoxia, Brain / Q000150:complications / Q000209:etiology / Q000628:therapy*; D020925:Hypoxia-Ischemia, Brain / Q000628:therapy; D009207:Myoclonus / Q000209:etiology; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic; D011379:Prognosis; D020127:Recovery of Function; D012640:Seizures / Q000209:etiology; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D018696:Neuroprotective Agents