title: [Bone health in Geneva retirees].
abstract: GERICO (Geneva Retirees Cohort) is a cohort of 953 men and women recruited at the age of 65 in Canton of Geneva, Switzerland, providing a picture of bone health at retirement time. Despite few comorbidities and good nutritional intake and vitamin D status, 30% of subjects have a history of vertebral or clinical fracture after the age of 45, 20% of women and 11% of men have osteoporosis assessed by DXA. 22% have a 10-year probability of a major osteoporotic fracture assessed by FRAX greater than 15%, -i.e. the current intervention thresholds recommended in this age-class in Switzerland. Nevertheless, only 1.4% subject benefits of an anti-osteoporotic drug. These data underscore the importance of primary and secondary prevention of osteoporosis and fractures in healthy elderly at time of retirement.
authors.forename: E
authors.initials: E
authors.lastname: Biver
authors.forename: C
authors.initials: C
authors.lastname: Durosier
authors.forename: T
authors.initials: T
authors.lastname: Chevalley
authors.forename: R
authors.initials: R
authors.lastname: Rizzoli
authors.forename: S
authors.initials: S
authors.lastname: Ferrari
mesh_terms: D000368:Aged; D001842:Bone and Bones / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications / Q000453:epidemiology* / Q000628:therapy; D058866:Osteoporotic Fractures / Q000453:epidemiology* / Q000517:prevention & control; D011322:Primary Prevention / Q000379:methods; D055502:Secondary Prevention / Q000379:methods; D012737:Sex Factors; D013557:Switzerland / Q000453:epidemiology; D014807:Vitamin D / Q000097:blood
chemical_list: D014807:Vitamin D