title: Bullous Eruption Associated With Dihydropyridines With Cross Reactivity.
abstract: The spectrum of cutaneous eruptions associated with dihydropyridines is extensive, varying from exanthemas to severe adverse events. We report a case of bullous eruption, one month after starting nicardipine and lercanidipine. The same symptoms recurred few days after taking nitrendipine.
authors.affiliation: National Center of Pharmacovigilance, Tunis, Tunisia.
authors.forename: Ons
authors.initials: O
authors.lastname: Charfi
authors.affiliation: National Center of Pharmacovigilance, Tunis, Tunisia - Tunis El Manar University, Faculty of Medicine, La Rabta, Tunis, Tunisia.
authors.forename: Ghozlane
authors.initials: G
authors.lastname: Lakhoua
authors.affiliation: National Center of Pharmacovigilance, Tunis, Tunisia - Tunis El Manar University, Faculty of Medicine, La Rabta, Tunis, Tunisia.
authors.forename: Rym
authors.initials: R
authors.lastname: Sahnoun
authors.affiliation: National Center of Pharmacovigilance, Tunis, Tunisia - Tunis El Manar University, Faculty of Medicine, La Rabta, Tunis, Tunisia.
authors.forename: Riadh
authors.initials: R
authors.lastname: Daghfous
authors.affiliation: National Center of Pharmacovigilance, Tunis, Tunisia - Tunis El Manar University, Faculty of Medicine, La Rabta, Tunis, Tunisia.
authors.forename: Sihem
authors.initials: S
authors.lastname: El Aidli
authors.affiliation: National Center of Pharmacovigilance, Tunis, Tunisia - Tunis El Manar University, Faculty of Medicine, La Rabta, Tunis, Tunisia.
authors.forename: Sarrah
authors.initials: S
authors.lastname: Kastalli
authors.affiliation: National Center of Pharmacovigilance, Tunis, Tunisia - Tunis El Manar University, Faculty of Medicine, La Rabta, Tunis, Tunisia.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Zaïem
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000276:immunology; D003429:Cross Reactions; D004095:Dihydropyridines / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology; D003875:Drug Eruptions / Q000175:diagnosis / Q000276:immunology; D004347:Drug Interactions; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000276:immunology; D009529:Nicardipine / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000175:diagnosis / Q000276:immunology
chemical_list: D000959:Antihypertensive Agents; D004095:Dihydropyridines; D009529:Nicardipine; C060343:lercanidipine