title: Laparoscopic vaginoplasty using a single peritoneal flap: 10 years of experience in the creation of a neovagina in patients with Mayer-Rokitansky-Küster-Hauser syndrome.
abstract: OBJECTIVE
  To assess anatomical and functional outcomes of a novel laparoscopic vaginoplasty technique using a single peritoneal flap (SPF) in patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome.
  
  
  METHODS
  Prospective follow-up study.
  
  
  METHODS
  University-based tertiary-care hospital.
  
  
  METHODS
  Patients with MRKH syndrome (n = 83) and randomly selected frequency-matched age-comparable healthy women serving as controls (n = 85).
  
  
  METHODS
  From March 2004 to March 2014, a total of 83 patients with MRKH syndrome underwent laparoscopic vaginoplasty using an SPF.
  
  
  METHODS
  Intraoperative parameters, postoperative parameters, and anatomical outcomes were recorded. The functional results of patients who became sexually active were assessed using the Female Sexual Function Index (FSFI) questionnaire and were compared with those of the controls.
  
  
  RESULTS
  Laparoscopic vaginoplasty using an SPF was successfully performed in all 83 patients, with no intraoperative complications. The mean operative time and intraoperative blood loss were, respectively, 71.2 ± 18.9 minutes and 88.5 ± 57.2 ml. The mean length and width of the neovagina at the 6-month follow-up examination were, respectively, 8.2 ± 0.8 cm and 3.0 ± 0.6 cm. Anatomical success was achieved in all patients. At 12 months after surgery, functional success, as assessed by the FSFI questionnaire, was achieved in 95.3% of patients. The FSFI scores did not differ significantly between patients with MRKH and healthy women in a control group.
  
  
  CONCLUSIONS
  Laparoscopic vaginoplasty using an SPF may be a feasible and effective approach that has satisfactory anatomical and functional outcomes for patients with MRKH syndrome.
authors.affiliation: Department of Obstetrics and Gynecology, Fourth Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China.
authors.forename: Xi-Wa
authors.initials: XW
authors.lastname: Zhao
authors.affiliation: Department of Obstetrics and Gynecology, Fourth Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China.
authors.forename: Jun-Ying
authors.initials: JY
authors.lastname: Ma
authors.affiliation: Department of Obstetrics and Gynecology, Fourth Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China.
authors.forename: Yan-Xiu
authors.initials: YX
authors.lastname: Wang
authors.affiliation: Department of Obstetrics and Gynecology, Fourth Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Obstetrics and Gynecology, Fourth Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Obstetrics and Gynecology, Fourth Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China. Electronic address: ssyfk2008@163.com.
authors.forename: Shan
authors.initials: S
authors.lastname: Kang
mesh_terms: D058489:46, XX Disorders of Sex Development / Q000175:diagnosis / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000013:Congenital Abnormalities / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000379:methods; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D009095:Mullerian Ducts / Q000002:abnormalities* / Q000601:surgery; D010502:Perineum / Q000601:surgery*; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods*; D013524:Surgical Flaps; D013997:Time Factors; D016896:Treatment Outcome; D014621:Vagina / Q000002:abnormalities / Q000601:surgery*; D055815:Young Adult
keywords: MRKH syndrome; laparoscopic vaginoplasty; neovagina; sexual function; single peritoneal flap