title: RGD-decorated conjugated polymer particles as fluorescent biomedical probes prepared by Sonogashira dispersion polymerization.
abstract: Here, we present a facile one-step Sonogashira dispersion polymerization affording monodisperse conjugated polymer particles bearing accessible acetylene moieties on the surface. These acetylene groups are easily functionalized with biological recognition motifs using thiol-yne click chemistry. The resulting functional particles are applied as fluorescent probes for imaging of activated endothelial cells, which take up the particles via receptor mediated endocytosis.
authors.affiliation: DWI - Leibniz Institute for Interactive Materials, RWTH Aachen University, Forckenbeckstraße 50, 52074 Aachen, Germany. kuehne@dwi.rwth-aachen.de.
authors.forename: Naveed
authors.initials: N
authors.lastname: Anwar
authors.forename: Anne
authors.initials: A
authors.lastname: Rix
authors.forename: Wiltrud
authors.initials: W
authors.lastname: Lederle
authors.forename: Alexander J C
authors.initials: AJ
authors.lastname: Kuehne