title: Application of Thio-Ugi Adducts for the Preparation of Benzo[b]thiophene and S-Heterocycle Library via Copper Catalyzed Intramolecular C-S Bond Formation.
abstract: Fused heterocycles, such as benzo[b]thiophene, thiochroman, benzo[b][1,4]thiazine, and 1,4-benzothiazepine were generated from thio-Ugi adducts containing a thioamide group through copper-catalyzed intramolecular C-S bond formation under microwave irradiation.
authors.affiliation: Innovative Drug Library Research Center, Department of Chemistry, College of Science, Dongguk University, 26, 3-ga, Pil-dong Jung-gu, Seoul 100-715, Korea.
authors.forename: Yong-Sang
authors.initials: YS
authors.lastname: Kim
authors.affiliation: Innovative Drug Library Research Center, Department of Chemistry, College of Science, Dongguk University, 26, 3-ga, Pil-dong Jung-gu, Seoul 100-715, Korea.
authors.forename: Se Hun
authors.initials: SH
authors.lastname: Kwak
authors.affiliation: Innovative Drug Library Research Center, Department of Chemistry, College of Science, Dongguk University, 26, 3-ga, Pil-dong Jung-gu, Seoul 100-715, Korea.
authors.forename: Young-Dae
authors.initials: YD
authors.lastname: Gong
mesh_terms: D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques / Q000379:methods*; D003300:Copper / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008872:Microwaves; D013455:Sulfur / Q000737:chemistry*; D013841:Thiazepines / Q000138:chemical synthesis; D013876:Thiophenes / Q000737:chemistry*
chemical_list: D006571:Heterocyclic Compounds; D007202:Indicators and Reagents; D013841:Thiazepines; D013876:Thiophenes; C088015:benzothiophene; D013455:Sulfur; D002244:Carbon; D003300:Copper
keywords: benzothiazepine; benzothiazine; benzothiophene; copper; thio-Ugi; thiochroman