title: Assessment of Factors Affecting the Usefulness and Diagnostic Yield of Core Biopsy Needles with a Side Hole in Endoscopic Ultrasound-Guided Fine-Needle Aspiration.
abstract: OBJECTIVE
  A barbed puncture needle with a side hole was recently developed to improve sample quality and quantity in endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). In this study, we retrospectively assessed the usefulness of this puncture needle.
  
  
  METHODS
  Factors affecting diagnostic yield, safety, and diagnostic accuracy were investigated in 76 patients who consecutively underwent EUS-FNA for neoplastic lesions at our hospital between January and December 2013.
  
  
  RESULTS
  The procedure was successful in all cases; the rates of sample collection and determination of the correct diagnosis were 92.1% and 89.5%, respectively. The mean number of needle passes required for diagnosis was 1.1. Complications included mild intraluminal bleeding in two patients (2.6%). Multivariate analysis revealed that lesion size (≤20 mm) was significantly associated with a decreased chance of determining the correct diagnosis.
  
  
  CONCLUSIONS
  Core biopsy needles with a side hole are safe and provide a satisfactory diagnostic yield. However, the side hole may potentially reduce the rate of making the correct diagnosis in small lesions.
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Tadahisa
authors.initials: T
authors.lastname: Inoue
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Okumura
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Mizushima
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Hirotada
authors.initials: H
authors.lastname: Nishie
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Iwasaki
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Kaiki
authors.initials: K
authors.lastname: Anbe
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Takanori
authors.initials: T
authors.lastname: Ozeki
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Kenta
authors.initials: K
authors.lastname: Kachi
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Shigeki
authors.initials: S
authors.lastname: Fukusada
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Yuta
authors.initials: Y
authors.lastname: Suzuki
authors.affiliation: Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Gifu, Japan.
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Sano
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004067:Digestive System Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000295:instrumentation*; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D041981:Gastrointestinal Tract / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009339:Needles / Q000009:adverse effects / Q000706:statistics & numerical data*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric
keywords: Biopsy needles; Endoscopic ultrasound-guided fine needle aspiration; Side hole; Size of lesions