title: Reversal of jaundice in two patients with inoperable cholangiocarcinoma treated with Cisplatin and gemcitabine combination.
abstract: Two patients are presented with severe jaundice, due to inoperable cholangiocarcinoma. The chemotherapeutic approach in patients with severe jaundice is discussed. Many schedules of chemotherapy were developed in this tumor type with normal serum bilirubin. We report here the first successful use of cisplatin and gemcitabine combination chemotherapy in these patients. Tolerability was good and liver function tests gradually improved.
authors.affiliation: Department of Medical Oncology, Regionaal Ziekenhuis SINT MARIA, Ziekenhuislaan 100, 1500 Halle, Belgium ; Department of Gastroenterology, Regionaal Ziekenhuis SINT MARIA, Ziekenhuislaan 100, 1500 Halle, Belgium.
authors.forename: Maarten
authors.initials: M
authors.lastname: Criel
authors.affiliation: Department of Medical Oncology, Regionaal Ziekenhuis SINT MARIA, Ziekenhuislaan 100, 1500 Halle, Belgium ; Department of Gastroenterology, Regionaal Ziekenhuis SINT MARIA, Ziekenhuislaan 100, 1500 Halle, Belgium.
authors.forename: Filip
authors.initials: F
authors.lastname: Geurs
authors.affiliation: Department of Medical Oncology, Regionaal Ziekenhuis SINT MARIA, Ziekenhuislaan 100, 1500 Halle, Belgium ; Department of Gastroenterology, Regionaal Ziekenhuis SINT MARIA, Ziekenhuislaan 100, 1500 Halle, Belgium.
authors.forename: Siegfried
authors.initials: S
authors.lastname: Ponette
authors.affiliation: Department of Medical Oncology, Regionaal Ziekenhuis SINT MARIA, Ziekenhuislaan 100, 1500 Halle, Belgium ; Department of Gastroenterology, Regionaal Ziekenhuis SINT MARIA, Ziekenhuislaan 100, 1500 Halle, Belgium.
authors.forename: Katrien
authors.initials: K
authors.lastname: Bulte
authors.affiliation: Department of Medical Oncology, Regionaal Ziekenhuis SINT MARIA, Ziekenhuislaan 100, 1500 Halle, Belgium ; Department of Gastroenterology, Regionaal Ziekenhuis SINT MARIA, Ziekenhuislaan 100, 1500 Halle, Belgium.
authors.forename: Johan
authors.initials: J
authors.lastname: Ponette