title: Author's view: radiation and immunotherapy as systemic therapy for solid tumors.
abstract: The ability of tumors to evade detection by the immune system via inducing immunosuppression prompted the therapeutic development of immune checkpoint inhibitors. In our recent review, we discussed findings from preclinical and clinical investigations of these agents utilized in combination with radiation inducing abscopal (systemic) antitumor effects.
authors.affiliation: Department of Radiation Oncology; The University of Texas MD Anderson Cancer Center; Houston, TX USA.
authors.forename: Steven N
authors.initials: SN
authors.lastname: Seyedin
authors.affiliation: Department of Radiation Oncology; The University of Texas MD Anderson Cancer Center; Houston, TX USA.
authors.forename: Chad
authors.initials: C
authors.lastname: Tang
authors.affiliation: Department of Radiation Oncology; The University of Texas MD Anderson Cancer Center; Houston, TX USA.
authors.forename: James W
authors.initials: JW
authors.lastname: Welsh
keywords: CTLA4; PD1; PDL1; abscopal effect; antibodies; immune checkpoint inhibitors; radiation therapy