title: Recent progress in the field of neoglycoconjugate chemistry.
abstract: Glycosylation is probably the most complex secondary gene event that affects the vast majority of proteins in nature resulting in the occurrence of a heterogeneous mixture of glycoforms for a single protein. Many functions are exerted by single monosaccharides, well-defined oligosaccharides, or larger glycans present in these glycoproteins. To unravel these functions it is of the utmost importance to prepare well-defined single glycans conjugated to the underlying aglycon. In this review, the most recent developments are described to address the preparation of carbohydrate-amino acid (glyco-conjugates). Naturally occurring N- and O-linked glycosylation are described and the preparation of non-natural sugar-amino acid linkages are also included.
authors.forename: Carmen
authors.initials: C
authors.lastname: Jiménez-Castells
authors.forename: Sira
authors.initials: S
authors.lastname: Defaus
authors.forename: David
authors.initials: D
authors.lastname: Andreu
authors.forename: Ricardo
authors.initials: R
authors.lastname: Gutiérrez-Gallego