title: Administration of a maple syrup extract to mitigate their hepatic inflammation induced by a high-fat diet: a transcriptome analysis.
abstract: Effects of the administration of maple syrup extract (MSX) on hepatic gene expression were investigated in mice fed a high-fat diet. Gene annotation enrichment analysis based on gene ontology revealed some changes in the expression of genes related to lipid metabolism and the immune response in MSX-fed mice. Detailed analysis of these data indicated that MSX ingestion mitigates hepatic inflammation.
authors.affiliation: a Project on Health and Anti-aging , Kanagawa Academy of Science and Technology , Kawasaki , Japan.
authors.forename: Asuka
authors.initials: A
authors.lastname: Kamei
authors.affiliation: a Project on Health and Anti-aging , Kanagawa Academy of Science and Technology , Kawasaki , Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Watanabe
authors.affiliation: a Project on Health and Anti-aging , Kanagawa Academy of Science and Technology , Kawasaki , Japan.
authors.forename: Fumika
authors.initials: F
authors.lastname: Shinozaki
authors.affiliation: a Project on Health and Anti-aging , Kanagawa Academy of Science and Technology , Kawasaki , Japan.
authors.forename: Akihito
authors.initials: A
authors.lastname: Yasuoka
authors.affiliation: a Project on Health and Anti-aging , Kanagawa Academy of Science and Technology , Kawasaki , Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kondo
authors.affiliation: b Graduate School of Agricultural and Life Science , The University of Tokyo , Tokyo , Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Ishijima
authors.affiliation: b Graduate School of Agricultural and Life Science , The University of Tokyo , Tokyo , Japan.
authors.forename: Tsudoi
authors.initials: T
authors.lastname: Toyoda
authors.affiliation: a Project on Health and Anti-aging , Kanagawa Academy of Science and Technology , Kawasaki , Japan.|c General Research Institute , Tokyo University of Agriculture , Tokyo , Japan.
authors.forename: Soichi
authors.initials: S
authors.lastname: Arai
authors.affiliation: a Project on Health and Anti-aging , Kanagawa Academy of Science and Technology , Kawasaki , Japan.|b Graduate School of Agricultural and Life Science , The University of Tokyo , Tokyo , Japan.
authors.forename: Keiko
authors.initials: K
authors.lastname: Abe
mesh_terms: D031002:Acer / Q000737:chemistry; D000818:Animals; D059305:Diet, High-Fat / Q000009:adverse effects; D015870:Gene Expression / Q000187:drug effects; D007249:Inflammation / Q000188:drug therapy* / Q000473:pathology; D050356:Lipid Metabolism / Q000187:drug effects / Q000235:genetics; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D051379:Mice; D010936:Plant Extracts / Q000008:administration & dosage* / Q000737:chemistry; D059467:Transcriptome / Q000187:drug effects / Q000235:genetics*
chemical_list: D010936:Plant Extracts
keywords: immune response; inflammation; lipid metabolism; liver; maple syrup