title: Dual Intragastric Balloon: Single Ambulatory Center Spanish Experience with 60 Patients in Endoscopic Weight Loss Management.
abstract: BACKGROUND
  Many obese patients fail conventional medical management and decline bariatric surgery. Less invasive weight loss options such as intragastric balloons may provide an opportunity to reach this large number of untreated patients. The aim of this study was to investigate the safety and effectiveness of the Dual Intragastric Balloon (DIGB) in the treatment of obese patients, as well as the impact of degree of obesity, age, and gender.
  
  
  METHODS
  The study was conducted at the Bariatric Endoscopy Unit of the Madrid Sanchinarro University Hospital. Sixty patients (11 men, 49 women) underwent endoscopic placement of a DIGB filled with a total of 900 cc of saline (450 cc in each balloon) for at least 6 months, along with regular counseling from a multidisciplinary team. Study outcomes included: change in body weight (TBWL), % of loss of initial body weight (%TBWL), % of excess body weight loss (%EWL), and adverse events.
  
  
  RESULTS
  Initial BMI 38.8 kg/m(2) decreased 6.1 units, with mean TBWL, %TBWL, and %EWL of 16.6 kg, 15.4 %, and 47.1 %, respectively. We found no difference in %TBWL between grade of obesity, age or sex, but morbidly obese patients demonstrated greater TBWL, and women and less obese subjects obtained higher %EWL. The DIGB was generally well tolerated, with one early removal for patient intolerance, one early deflation without migration, and one gastric perforation. Fourteen patients had small, clinically insignificant ulcers or erosions noted at the time of removal.
  
  
  CONCLUSIONS
  The present study shows that the DIGB was easy to use, resulted in significant weight loss, safe, and well tolerated.
authors.affiliation: Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, C/Oña n° 10, 28050, Madrid, Spain. gontrandlopeznava@gmail.com.
authors.forename: G
authors.initials: G
authors.lastname: Lopez-Nava
authors.affiliation: Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, C/Oña n° 10, 28050, Madrid, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Bautista-Castaño
authors.affiliation: Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, C/Oña n° 10, 28050, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Jimenez-Baños
authors.affiliation: Bariatric Endoscopy Unit, Madrid Sanchinarro University Hospital, C/Oña n° 10, 28050, Madrid, Spain.
authors.forename: J P
authors.initials: JP
authors.lastname: Fernandez-Corbelle
mesh_terms: D000328:Adult; D000554:Ambulatory Care Facilities; D050110:Bariatric Surgery / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D015992:Body Mass Index; D016099:Endoscopy, Gastrointestinal / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D005260:Female; D015905:Gastric Balloon / Q000009:adverse effects / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000453:epidemiology / Q000601:surgery*; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D016896:Treatment Outcome; D015431:Weight Loss; D061217:Weight Reduction Programs / Q000379:methods / Q000706:statistics & numerical data; D055815:Young Adult
keywords: Bariatric endoscopy; Dual intragastric balloon; Obesity treatment