title: Stroma, Stroma Everywhere (Far More Than You Think).
abstract: Pancreatic ductal adenocarcinomas with high stromal content are shown to have greatly reduced overall survival, consistent with previous reports that stroma may limit drug delivery. In contrast to expectations, metastatic lesions were found to harbor as much stroma as primary tumors.
authors.affiliation: Division of Digestive and Liver Diseases, Department of Medicine and Department of Pathology, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York. kenolive@columbia.edu.
authors.forename: Kenneth P
authors.initials: KP
authors.lastname: Olive
mesh_terms: D000230:Adenocarcinoma / Q000378:metabolism*; D014408:Biomarkers, Tumor / Q000378:metabolism*; D021441:Carcinoma, Pancreatic Ductal / Q000378:metabolism*; D005109:Extracellular Matrix / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D014408:Biomarkers, Tumor