title: Frustrated Lewis pair chemistry: development and perspectives.
abstract: Frustrated Lewis pairs (FLPs) are combinations of Lewis acids and Lewis bases in solution that are deterred from strong adduct formation by steric and/or electronic factors. This opens pathways to novel cooperative reactions with added substrates. Small-molecule binding and activation by FLPs has led to the discovery of a variety of new reactions through unprecedented pathways. Hydrogen activation and subsequent manipulation in metal-free catalytic hydrogenations is a frequently observed feature of many FLPs. The current state of this young but rapidly expanding field is outlined in this Review and the future directions for its broadening sphere of impact are considered.
authors.affiliation: Department of Chemistry, University of Toronto, 80 St. George St, Toronto, Ontario M5S3H6 (Canada). dstephan@chem.utoronto.ca.
authors.forename: Douglas W
authors.initials: DW
authors.lastname: Stephan
authors.affiliation: Organisch Chemisches Institut, Westfälische Wilhelms-Universität, Corrensstr. 40, 48149 Münster (Germany). erker@uni-muenster.de.
authors.forename: Gerhard
authors.initials: G
authors.lastname: Erker
keywords: cooperative reactions; frustrated Lewis pairs; metal-free  hydrogenation; small-molecule  activation