title: Progressive renal insufficiency, hypercalcaemia, bicytopaenia and a history of breast cancer.
abstract: Sarcoidosis can affect all organs and may mimic a variety of other diseases. In the absence of typical pulmonary features, extrapulmonary manifestations may be difficult to diagnose. We describe here the very uncommon case of a patient with mild pulmonal involvement but distinct renal, bone marrow and lymph node sarcoidosis. Treatment with glucocorticoids significantly improved kidney function and normalized serum calcium levels as well as the blood count. This case underscores the importance of sarcoidosis to be considered as a differential diagnosis of renal failure associated with hypercalcaemia and nephrocalcinosis. Bone marrow involvement should always be suspected if mono-, bi- or pancytopaenia coexist.
authors.affiliation: Department of Medicine I and Nuclear Medicine , University of Luebeck , Luebeck , Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Letterer
authors.affiliation: Department of Medicine I and Nuclear Medicine , University of Luebeck , Luebeck , Germany.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Lindner
authors.affiliation: Department of Pathology and Nuclear Medicine , University of Luebeck , Luebeck , Germany.
authors.forename: Heinz-Wolfram
authors.initials: HW
authors.lastname: Bernd
authors.affiliation: Clinic for Radiology and Nuclear Medicine , University of Luebeck , Luebeck , Germany.
authors.forename: Florian M
authors.initials: FM
authors.lastname: Vogt
authors.affiliation: Kidney Registry, Institute of Pathology , University Hospital Hamburg-Eppendorf , Germany.
authors.forename: Udo
authors.initials: U
authors.lastname: Helmchen
authors.affiliation: Department of Medicine I and Nuclear Medicine , University of Luebeck , Luebeck , Germany.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Lehnert
authors.affiliation: Department of Medicine I and Nuclear Medicine , University of Luebeck , Luebeck , Germany.
authors.forename: Christian S
authors.initials: CS
authors.lastname: Haas
keywords: bone marrow; interstitial nephritis; renal insufficiency; sarcoidosis