title: Dramatic response to selective internal radiation therapy for unresectable hepatocellular carcinoma.
abstract: A 54-year-old woman with a known history of multifocal hepatocellular carcinoma was treated with selective internal radiation therapy (SIRT) using yttrium-90 ((90)Y) microspheres, despite disease relapses after surgical resection and transarterial chemoembolization. She developed a dramatic clinical, radiological and metabolic response after 9 weeks. This case provides visual illustration of the potential roles of SIRT in the treatment of hepatocellular carcinoma.
authors.affiliation: Department of Medical Oncology , Royal North Shore Hospital, St Leonards , Sydney, NSW , Australia.
authors.forename: Woo Daniel
authors.initials: WD
authors.lastname: Park
authors.affiliation: Department of Medicine, Division of Solid Tumor Oncology , Memorial Sloan Kettering Cancer Center , New York, NY , USA ; Sydney Medical School , University of Sydney , Sydney, NSW , Australia.
authors.forename: Bob T
authors.initials: BT
authors.lastname: Li
authors.affiliation: Department of Radiology , Royal North Shore Hospital , Sydney, NSW , Australia.
authors.forename: Richard
authors.initials: R
authors.lastname: Maher
authors.affiliation: Sydney Medical School , University of Sydney , Sydney, NSW , Australia ; Department of Gastrointestinal Surgery , Royal North Shore Hospital, St Leonards , Sydney, NSW , Australia ; Australian School of Advanced Medicine , Macquarie University, North Ryde , Sydney, NSW , Australia.
authors.forename: Jaswinder S
authors.initials: JS
authors.lastname: Samra
authors.affiliation: Department of Medical Oncology , Royal North Shore Hospital, St Leonards , Sydney, NSW , Australia ; Sydney Medical School , University of Sydney , Sydney, NSW , Australia.
authors.forename: Stephen
authors.initials: S
authors.lastname: Clarke
authors.affiliation: Sydney Medical School , University of Sydney , Sydney, NSW , Australia ; Department of Nuclear Medicine , Royal North Shore Hospital , Sydney, NSW , Australia.
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Bernard
authors.affiliation: Department of Nuclear Medicine , Royal North Shore Hospital , Sydney, NSW , Australia ; Faculty of Health Sciences , University of Sydney , Sydney, NSW , Australia.
authors.forename: Dale L
authors.initials: DL
authors.lastname: Bailey
authors.affiliation: Department of Medical Oncology , Royal North Shore Hospital, St Leonards , Sydney, NSW , Australia ; Sydney Medical School , University of Sydney , Sydney, NSW , Australia.
authors.forename: Nick
authors.initials: N
authors.lastname: Pavlakis