title: A case of primary immune deficiency presenting with nephrotic syndrome.
abstract: Common variable immunodeficiency (CVID) is the most common form of severe antibody deficiency. The disorder is associated with a broad spectrum of clinical manifestations, including infections and chronic lung, gastrointestinal and autoimmune diseases. A 29-year-old female patient has had frequent sinopulmonary infections and gastroenteritis for the last 20 years and had been given broad-spectrum antibiotics for treatment. Immunoglobulin (Ig) levels were at undetectable levels. Renal biopsy was consistent with AA amyloidosis. She is now under follow-up with periodic intravenous Ig treatment without any infection during the last 10 months. CVID must be kept in mind in patients with recurrent sinopulmonary infections.
authors.affiliation: Department of Nephrology , Haseki Training and Research Hospital , Istanbul , Turkey.
authors.forename: Zeki
authors.initials: Z
authors.lastname: Aydin
authors.affiliation: Department of Nephrology , Haseki Training and Research Hospital , Istanbul , Turkey.
authors.forename: Meltem
authors.initials: M
authors.lastname: Gursu
authors.affiliation: Department of Nephrology , Haseki Training and Research Hospital , Istanbul , Turkey.
authors.forename: Savas
authors.initials: S
authors.lastname: Ozturk
authors.affiliation: Department of Pathology, Istanbul Medical Faculty , Istanbul University , Istanbul , Turkey.
authors.forename: Isın
authors.initials: I
authors.lastname: Kilicaslan
authors.affiliation: Department of Nephrology , Haseki Training and Research Hospital , Istanbul , Turkey.
authors.forename: Rumeyza
authors.initials: R
authors.lastname: Kazancioglu
keywords: amyloidosis; common variable immunodeficiency; nephrotic syndrome