title: CAR Signaling Domains Regulate T-Cell Exhaustion and Clinical Efficacy.
mesh_terms: D000818:Animals; D018106:CD28 Antigens / Q000737:chemistry; D017252:CD3 Complex / Q000737:chemistry; D006801:Humans; D016219:Immunotherapy, Adoptive; D051379:Mice; D009369:Neoplasms / Q000628:therapy*; D011948:Receptors, Antigen, T-Cell / Q000737:chemistry* / Q000235:genetics; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology / Q000637:transplantation*
chemical_list: C000605956:CD19-specific chimeric antigen receptor; D018106:CD28 Antigens; D017252:CD3 Complex; C121704:CD3 antigen, zeta chain; D011948:Receptors, Antigen, T-Cell