title: Pharmacologic management of chronic stable angina.
abstract: Chronic stable angina is a significant problem in older adults. The goal of therapy is to provide symptomatic relief, improve patient quality of life, and prevent subsequent angina or myocardial infarction that could lead to sudden death. The efficacy and safety of drugs such as beta-blockers and calcium channel blockers for managing chronic stable angina in older adults has not been rigorously investigated. Drug selection should be based on physiologic alterations, patient comorbidities, adverse reaction profile, and cost.
authors.affiliation: Deepali Dixit is a clinical assistant professor in the Department of Pharmacy Practice and Administration at Rutgers, The State University of New Jersey, in Piscataway, N.J. Katarzyna Kimborowicz is a critical care specialist at Morristown (N.J.) Medical Center. The authors have disclosed no potential conflicts of interest, financial or otherwise.
authors.forename: Deepali
authors.initials: D
authors.lastname: Dixit
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Kimborowicz
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D060050:Angina, Stable / Q000188:drug therapy*; D001552:Benzazepines / Q000627:therapeutic use; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D006801:Humans; D007548:Isosorbide Dinitrate / Q000031:analogs & derivatives / Q000627:therapeutic use; D000077550:Ivabradine; D020108:Nicorandil / Q000627:therapeutic use; D005996:Nitroglycerin / Q000627:therapeutic use; D000069458:Ranolazine / Q000627:therapeutic use; D026941:Sodium Channel Blockers / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D000319:Adrenergic beta-Antagonists; D001552:Benzazepines; D002121:Calcium Channel Blockers; D002317:Cardiovascular Agents; D026941:Sodium Channel Blockers; D014665:Vasodilator Agents; D020108:Nicorandil; D000077550:Ivabradine; D000069458:Ranolazine; D005996:Nitroglycerin; D007548:Isosorbide Dinitrate; C030397:isosorbide-5-mononitrate