title: Anaphylactic-like reaction from trimethoprim-sulfamethoxazole in a patient with AIDS.
abstract: We report a patient with AIDS who had an anaphylactic-like reaction from trimethoprim-sulfamethoxazole. Clinical suspicion of anaphylaxis should be considered in patients presenting with fever, hypotension, eosinophilia, rash, flushing or pulmonary infiltrates after initial exposure and re-exposure to the medication. This case highlights the need for healthcare professionals to be reminded of the association between this unusual antibiotic reaction resembling sepsis and HIV disease.
authors.affiliation: Department of Internal Medicine, Riverside County Regional Medical Center, Moreno Valley, CA, USA jpersich@co.riverside.ca.us.
authors.forename: Jon
authors.initials: J
authors.lastname: Persichino
authors.affiliation: Infectious Disease Section, Riverside County Regional Medical Center, Moreno Valley, CA, USA.
authors.forename: Made
authors.initials: M
authors.lastname: Sutjita
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000517:prevention & control*; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D000707:Anaphylaxis; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D004342:Drug Hypersensitivity; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy / Q000517:prevention & control*; D063106:Transgender Persons; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000008:administration & dosage* / Q000627:therapeutic use; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
keywords: AIDS; HIV; Trimethoprim-sulfamethoxazole; adverse drug reaction; anaphylaxis; sepsis