title: Insecticidal properties of essential oils against Tribolium castaneum (Herbst) and their inhibitory effects on acetylcholinesterase and adenosine triphosphatases.
abstract: Essential oils from 20 Egyptian plants were obtained by using hydrodistillation. The chemical composition of the isolated oils was identified by gas chromatograph/mass spectrometer. Fumigant and contact toxicities of the essential oils were evaluated against the adults of Tribolium castaneum. In fumigation assays, the oil of Origanum vulgare (LC50 = 9.97 mg/L air) displayed the highest toxicity towards the adults of T. castaneum. In contact assays, the oils of Artemisia monosperma (LC50 = 0.07 mg/cm(2)) and O. vulgare (LC50 = 0.07 mg/cm(2)) were the most potent toxicants against the adults of T. castaneum. Biochemical studies showed that the tested oils caused pronounced inhibition of acetylcholinesterase (AChE) and adenosine triphosphatases (ATPases) isolated from the larvae of T. castaneum. The oil Cupressus macrocarpa (IC50 = 12.3 mg/L) was the most potent inhibitor of AChE, while the oil of Calistemon viminals (IC50 = 4.4 mg/L) was the most potent inhibitor of ATPases.
authors.affiliation: a Plant Protection Research Institute, Agricultural Research Center, Sabahia , Alexandria , Egypt.
authors.forename: Hamdy K
authors.initials: HK
authors.lastname: Abou-Taleb
authors.affiliation: a Plant Protection Research Institute, Agricultural Research Center, Sabahia , Alexandria , Egypt.
authors.forename: Magdy I E
authors.initials: MI
authors.lastname: Mohamed
authors.affiliation: b Department of Pesticide Chemistry , Faculty of Agriculture, Alexandria University , 21545 El-Shatby, Alexandria , Egypt.
authors.forename: Mohamed S
authors.initials: MS
authors.lastname: Shawir
authors.affiliation: b Department of Pesticide Chemistry , Faculty of Agriculture, Alexandria University , 21545 El-Shatby, Alexandria , Egypt.
authors.forename: Samir A M
authors.initials: SA
authors.lastname: Abdelgaleil
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors*; D000818:Animals; D019306:Artemisia / Q000737:chemistry; D002800:Cholinesterase Inhibitors / Q000737:chemistry* / Q000302:isolation & purification; D005651:Fumigation; D008401:Gas Chromatography-Mass Spectrometry; D007306:Insecticides / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry*; D031341:Origanum / Q000737:chemistry; D014231:Tribolium
chemical_list: D002800:Cholinesterase Inhibitors; D007306:Insecticides; D009822:Oils, Volatile; D000110:Acetylcholinesterase; D000251:Adenosine Triphosphatases
keywords: acetylcholinesterase; adenosine triphosphatases; contact toxicity; Tribolium castaneum; essential oils; fumigant toxicity