title: [Modification of radiosensitivity in maignant and normal tissues during radiotherapy of malignant neoplasms].
abstract: The results of treatment of cancer patients have not undergone any significant changes in recent years. This is due to the fact that opportunities to improve the outcomes by developing radiation therapy equipment and op- timizing the dose delivery are largely exhausted. However, there is a proven, but practically not utilized way--the use of radiomodifiers. This paper presents the experience of more than 25 years of clinical use of radiomodification in the Russian Scientific Center of Radiology and Modern Surgery Technologies. Simplicity, avai- lability, and stability of the results allow considering the use of radiomodification as one of the possible ways to improve the effectiveness of radiotherapy.
authors.forename: N Y
authors.initials: NY
authors.lastname: Neklasova
authors.forename: G M
authors.initials: GM
authors.lastname: Zharinov
authors.forename: A N
authors.initials: AN
authors.lastname: Grebenyuk
mesh_terms: D004121:Dimethyl Sulfoxide / Q000627:therapeutic use; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D009369:Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D011836:Radiation Tolerance / Q000187:drug effects*; D011838:Radiation-Sensitizing Agents / Q000627:therapeutic use
chemical_list: D011838:Radiation-Sensitizing Agents; D008795:Metronidazole; D004121:Dimethyl Sulfoxide