title: Biological activity of natural sesquiterpenoids containing a gem-dimethylcyclopropane unit.
abstract: The biological activities of aristolane, aromadendrane, ent-1,10-secoaromadendrane, 2,3-secoaromadendrane, ent-5,10-cycloaromadendrane, bicyclogermacrene, lepidozane, and maaliane terpenoids which contain the gem-dimethylcyclopropyl unit are described. Particular attention is given to their anti-viral, anti-microbial and cytotoxic activities. In the main text there are 119 references covering the literature from 1963-2014. The ESI contains tables listing 332 of these terpenoids, their occurrence and biological activity together with the related references.
authors.affiliation: Department of Organic Chemistry, Faculty of Science, University of Cádiz, Polígono Río San Pedro s/n, 11510, Puerto Real, Cádiz, Spain. isidro.gonzalez@uca.es rosario.hernandez@uca.es.
authors.forename: María Jesús
authors.initials: MJ
authors.lastname: Durán-Peña
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Botubol Ares
authors.forename: James R
authors.initials: JR
authors.lastname: Hanson
authors.forename: Isidro G
authors.initials: IG
authors.lastname: Collado
authors.forename: Rosario
authors.initials: R
authors.lastname: Hernández-Galán
mesh_terms: D001688:Biological Products / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000494:pharmacology
chemical_list: D001688:Biological Products; D012717:Sesquiterpenes