title: Uveitis secondary to leishmaniasis immune reconstitution syndrome in a HIV-positive patient.
abstract: We describe the case of a HIV-positive patient treated for visceral leishmaniasis who developed uveitis as part of a leishmaniasis immune reconstitution syndrome. Visceral leishmaniasis is increasingly found in HIV-positive adults. Its ophthalmic manifestations can range from relatively minor to complicated anterior uveitis, leading to secondary glaucoma and loss of vision. Clinicians caring for people living with HIV should be alert to the complications of leishmaniasis that can occur before and during treatment.
authors.affiliation: Department of Genitourinary Medicine, Guy's & St Thomas' NHS Foundation Trust, Westminster Bridge Road, London, UK odavies@doctors.net.uk.
authors.forename: Olubanke
authors.initials: O
authors.lastname: Davies
authors.affiliation: Medical Eye Unit, Guy's & St Thomas' NHS Foundation Trust, Westminster Bridge Road, London, UK.
authors.forename: Felicity
authors.initials: F
authors.lastname: Allen
authors.affiliation: Medical Eye Unit, Guy's & St Thomas' NHS Foundation Trust, Westminster Bridge Road, London, UK.
authors.forename: Anna M
authors.initials: AM
authors.lastname: Gruener
authors.affiliation: Department of Genitourinary Medicine, Guy's & St Thomas' NHS Foundation Trust, Westminster Bridge Road, London, UK.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Simons
authors.affiliation: Medical Eye Unit, Guy's & St Thomas' NHS Foundation Trust, Westminster Bridge Road, London, UK.
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Graham
authors.affiliation: Department of Genitourinary Medicine, Guy's & St Thomas' NHS Foundation Trust, Westminster Bridge Road, London, UK.
authors.forename: Nick
authors.initials: N
authors.lastname: Larbalestier
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications*; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D005334:Fever / Q000209:etiology; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D018451:Homosexuality, Male; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000150:complications*; D007893:Leishmania donovani / Q000302:isolation & purification; D007898:Leishmaniasis, Visceral / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D013163:Splenomegaly / Q000209:etiology; D016896:Treatment Outcome; D014605:Uveitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
chemical_list: D019380:Anti-HIV Agents
keywords: AIDS; Europe; HAART; HIV; antifungal; opportunistic infection; treatment; visceral leishmaniasis