title: Modelling the emergence of polarity  patterns for the intercellular transport  of auxin in plants.
abstract: The hormone auxin is actively transported throughout plants via protein machineries including the dedicated transporter known as PIN. The associated transport is ordered with nearby cells driving auxin flux in similar directions. Here, we provide a model of both the auxin transport and of the dynamics of cellular polarization based on flux sensing. Our main findings are: (i) spontaneous intracellular PIN polarization arises if PIN recycling dynamics are sufficiently nonlinear, (ii) there is no need for an auxin concentration gradient and (iii) ordered multi-cellular patterns of PIN polarization are favoured by molecular noise.
authors.forename: Silvia
authors.initials: S
authors.lastname: Grigolon
authors.forename: Peter
authors.initials: P
authors.lastname: Sollich
authors.forename: Olivier C
authors.initials: OC
authors.lastname: Martin
mesh_terms: D017360:Arabidopsis / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D002450:Cell Communication / Q000502:physiology*; D003198:Computer Simulation; D007210:Indoleacetic Acids / Q000378:metabolism*; D026901:Membrane Transport Proteins / Q000378:metabolism*; D008954:Models, Biological; D010937:Plant Growth Regulators / Q000378:metabolism; D021381:Protein Transport / Q000502:physiology
chemical_list: D029681:Arabidopsis Proteins; D007210:Indoleacetic Acids; D026901:Membrane Transport Proteins; D010937:Plant Growth Regulators