title: AA amyloidosis in a patient with Langerhans cell histiocytosis.
abstract: We report the case of a 37-year-old woman who presented with progressive renal dysfunction and proteinuria, in whom renal biopsy confirmed a diagnosis of AA amyloidosis. No evidence of chronic suppurative infection, connective tissue disease or malignancy was found. A past history of Langerhans cell histiocytosis (LCH) diagnosed in childhood was noted for which the patient had been successfully treated with surgical excision, corticosteroids, radiotherapy and chemotherapy. Renal disease in LCH is not widely recognized and thus we describe a patient with LCH in whom AA amyloidosis developed in the absence of any other established cause.
authors.affiliation: Renal Unit, Glasgow Royal Infirmary, Glasgow, UK.
authors.forename: Peter C
authors.initials: PC
authors.lastname: Thomson
authors.affiliation: Renal Unit, Glasgow Royal Infirmary, Glasgow, UK.
authors.forename: Alison H M
authors.initials: AH
authors.lastname: Taylor
authors.affiliation: Renal Unit, Glasgow Royal Infirmary, Glasgow, UK.
authors.forename: Scott T W
authors.initials: ST
authors.lastname: Morris
authors.affiliation: Department of Pathology, Western Infirmary, Glasgow, UK.
authors.forename: David
authors.initials: D
authors.lastname: Kipgen
authors.affiliation: Renal Unit, Glasgow Royal Infirmary, Glasgow, UK.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Mactier
keywords: Langerhans; amyloid; histiocytosis; proteinuria