title: Synthesis of amphiphilic polysuccinimide star copolymers for responsive delivery in plants.
abstract: While polymeric nanocarriers are widely used in medicine for controlled release and site-specific delivery, few reports have applied such delivery methods within agriculture, despite the urgent need for specific delivery of pesticides and nutrients. We report the synthesis of stimuli-responsive and biodegradable polymeric nanocarriers designed for delivery to the phloem of plants and describe methods employed to evaluate their toxicity in plant cells.
authors.affiliation: George & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry, University of Florida, Gainesville, Florida, USA. sumerlin@chem.ufl.edu.
authors.forename: Mingsheng
authors.initials: M
authors.lastname: Chen
authors.forename: Shaun P
authors.initials: SP
authors.lastname: Jensen
authors.forename: Megan R
authors.initials: MR
authors.lastname: Hill
authors.forename: Gloria
authors.initials: G
authors.lastname: Moore
authors.forename: Zhenli
authors.initials: Z
authors.lastname: He
authors.forename: Brent S
authors.initials: BS
authors.lastname: Sumerlin
mesh_terms: D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D002957:Citrus / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects; D004337:Drug Carriers; D016503:Drug Delivery Systems; D006863:Hydrogen-Ion Concentration; D008027:Light; D008823:Micelles; D053758:Nanoparticles / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry* / Q000494:pharmacology; D052585:Phloem / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects; D011108:Polymers / Q000138:chemical synthesis* / Q000494:pharmacology; D012639:Seeds / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects
chemical_list: D004337:Drug Carriers; D008823:Micelles; D010455:Peptides; D011108:Polymers; C025252:poly-DL-succinimide; D001224:Aspartic Acid