title: Metal-free one-pot synthesis of 2-substituted and 2,3-disubstituted morpholines from aziridines.
abstract: The metal-free synthesis of 2-substituted and 2,3-disubstituted morpholines through a one-pot strategy is described. A simple and inexpensive ammonium persulfate salt enables the reaction of aziridines with halogenated alcohols to proceed via an SN2-type ring opening followed by cyclization of the resulting haloalkoxy amine.
authors.affiliation: State Key Laboratory of Urban Water Resource and Environment, the Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, P. R. China.
authors.forename: Hongnan
authors.initials: H
authors.lastname: Sun
authors.affiliation: State Key Laboratory of Urban Water Resource and Environment, the Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, P. R. China.
authors.forename: Binbin
authors.initials: B
authors.lastname: Huang
authors.affiliation: State Key Laboratory of Urban Water Resource and Environment, the Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, P. R. China.
authors.forename: Run
authors.initials: R
authors.lastname: Lin
authors.affiliation: State Key Laboratory of Urban Water Resource and Environment, the Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, P. R. China.
authors.forename: Chao
authors.initials: C
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Urban Water Resource and Environment, the Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, P. R. China.
authors.forename: Wujiong
authors.initials: W
authors.lastname: Xia
keywords: ammonium persulfate; aziridine; metal free; morpholine