title: Progression of blood pressure and cardiovascular outcomes in hypertensive patients in a reference center.
abstract: BACKGROUND
  Hypertension is a public health problem, considering its high prevalence, low control rate and cardiovascular complications.
  
  
  OBJECTIVE
  Evaluate the control of blood pressure (BP) and cardiovascular outcomes in patients enrolled at the Reference Center for Hypertension and Diabetes, located in a medium-sized city in the Midwest Region of Brazil.
  
  
  METHODS
  Population-based study comparing patients enrolled in the service at the time of their admission and after an average follow-up of five years. Participants were aged ≥ 18 years and were regularly monitored at the Center up to 6 months before data collection. We assessed demographic variables, BP, body mass index, risk factors, and cardiovascular outcomes.
  
  
  RESULTS
  We studied 1,298 individuals, predominantly women (60.9%), and with mean age of 56.7 ± 13.1 years. Over time, there was a significant increase in physical inactivity, alcohol consumption, diabetes, dyslipidemia, and excessive weight. As for cardiovascular outcomes, we observed an increase in stroke and myocardial revascularization, and a lower frequency of chronic renal failure. During follow-up, there was significant improvement in the rate of BP control (from 29.6% to 39.6%; p = 0.001) and 72 deaths, 91.7% of which were due to cardiovascular diseases.
  
  
  CONCLUSIONS
  Despite considerable improvements in the rate of BP control during follow-up, risk factors worsened and cardiovascular outcomes increased.
authors.affiliation: Liga de Hipertensão, Faculdade de Medicina, Universidade Federal de Goiânia, Goiás, GO, Brazil.
authors.forename: Gilberto Campos
authors.initials: GC
authors.lastname: Guimarães Filho
authors.affiliation: Liga de Hipertensão, Faculdade de Medicina, Universidade Federal de Goiânia, Goiás, GO, Brazil.
authors.forename: Ana Luiza Lima
authors.initials: AL
authors.lastname: Sousa
authors.affiliation: Liga de Hipertensão, Faculdade de Medicina, Universidade Federal de Goiânia, Goiás, GO, Brazil.
authors.forename: Thiago de Souza Veiga
authors.initials: Tde S
authors.lastname: Jardim
authors.affiliation: Liga de Hipertensão, Faculdade de Medicina, Universidade Federal de Goiânia, Goiás, GO, Brazil.
authors.forename: Weimar Sebba Barroso
authors.initials: WS
authors.lastname: Souza
authors.affiliation: Liga de Hipertensão, Faculdade de Medicina, Universidade Federal de Goiânia, Goiás, GO, Brazil.
authors.forename: Paulo César Brandão Veiga
authors.initials: PC
authors.lastname: Jardim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology*; D015992:Body Mass Index; D001938:Brazil; D002318:Cardiovascular Diseases / Q000209:etiology / Q000401:mortality*; D018450:Disease Progression; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology; D050177:Overweight / Q000150:complications; D012307:Risk Factors; D057185:Sedentary Behavior; D020521:Stroke / Q000453:epidemiology; D055815:Young Adult