title: Primary cervical choriocarcinoma during viable intrauterine pregnancy.
abstract: A 31-year-old multigravida woman at 27 weeks' gestation was admitted with vaginal bleeding and a hypervascular mass near the cervix on ultrasonography. After discharge with improvement, she was readmitted the next day for uncontrolled, heavy vaginal bleeding and underwent emergency cesarean section at 29 weeks' gestation. A 3-cm friable mass found near the cervix was removed surgically; this lesion was shown to be primary cervical choriocarcinoma. On the 17th postoperative day the patient underwent total abdominal hysterectomy with preservation of both ovaries and biopsy was performed on the right ovary. The International Federation of Gynecology and Obstetrics (FIGO) stage was I and her World Health Organization prognostic score was 9, representing high risk. The patient received three rounds of chemotherapy until achieving three consecutive normal human chorionic gonadotropin levels with two additional courses to address risk of relapse. DNA genotyping on short tandem repeat polymorphism confirmed the gestational choriocarcinoma.
authors.affiliation: Departments of Obstetrics and Gynecology.
authors.forename: Minyoung
authors.initials: M
authors.lastname: Park
authors.affiliation: Departments of Obstetrics and Gynecology.
authors.forename: Seung-Su
authors.initials: SS
authors.lastname: Han
authors.affiliation: Departments of Obstetrics and Gynecology.
authors.forename: Eun-Ju
authors.initials: EJ
authors.lastname: Lee
authors.affiliation: Departments of Obstetrics and Gynecology.
authors.forename: Mina
authors.initials: M
authors.lastname: Byon
authors.affiliation: Departments of Obstetrics and Gynecology.
authors.forename: Mi-Young
authors.initials: MY
authors.lastname: Kim
authors.affiliation: Pathology, Chung-Ang University College of Medicine, Seoul, Korea.
authors.forename: Mi-Kyung
authors.initials: MK
authors.lastname: Kim
authors.affiliation: Departments of Obstetrics and Gynecology.
authors.forename: Gwang Jun
authors.initials: GJ
authors.lastname: Kim
mesh_terms: D000328:Adult; D002822:Choriocarcinoma / Q000628:therapy*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000628:therapy*; D002583:Uterine Cervical Neoplasms / Q000628:therapy*
keywords: cervical choriocarcinoma; gestational origin; pregnancy