title: Remission of splenic marginal zone lymphoma in a patient treated for hepatitis B: a case of HBV-associated lymphoma.
abstract: Splenomegaly is a common finding in chronic hepatitis B infection. We present the case of a man with an acute flare of chronic hepatitis B infection, where splenomegaly in absence of portal hypertension led to the diagnosis of splenic marginal zone lymphoma (SMZL) with bone marrow involvement. Adequate suppression of the hepatitis B virus (HBV) viral load with tenofovir resulted in complete remission of the lymphoma.
authors.forename: A W A
authors.initials: AW
authors.lastname: Koot
authors.forename: A P
authors.initials: AP
authors.lastname: Visscher
authors.forename: R M H G
authors.initials: RM
authors.lastname: Huits
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives / Q000494:pharmacology / Q000627:therapeutic use; D001853:Bone Marrow / Q000378:metabolism / Q000473:pathology; D006515:Hepatitis B virus; D019694:Hepatitis B, Chronic / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007150:Immunohistochemistry; D018442:Lymphoma, B-Cell, Marginal Zone / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D063065:Organophosphonates / Q000494:pharmacology / Q000627:therapeutic use; D012074:Remission Induction / Q000379:methods; D013160:Splenic Neoplasms / Q000209:etiology*; D000068698:Tenofovir; D019562:Viral Load / Q000187:drug effects
chemical_list: D063065:Organophosphonates; D000068698:Tenofovir; D000225:Adenine
keywords: Antiviral therapy,; B-cell non-Hodgkin lymphoma; Chronic hepatitis B,; SMZL,; Splenic marginal zone lymphoma,