title: COMPARISON OF SURGICAL OUTCOME OF 23-GAUGE AND 25-GAUGE MICROINCISION VITRECTOMY SURGERY FOR MANAGEMENT OF IDIOPATHIC EPIRETINAL MEMBRANE IN PSEUDOPHAKIC EYES.
abstract: OBJECTIVE
  To compare the visual outcomes and occurrences of postoperative complications after 23-gauge (G) and 25-G microincision vitrectomy surgery (MIVS) for idiopathic epiretinal membrane in pseudophakic eyes.
  
  
  METHODS
  A total of 239 pseudophakic eyes of 239 patients who underwent 23-G (n = 159) or 25-G MIVS (n = 80) for removal of idiopathic epiretinal membrane between March 2010 and March 2013 were included in this retrospective study. Patients were followed up on postoperative 1 day, 1 week, 1, 3, and 6 months. Postoperative visual acuity, intraocular pressure, and intraoperative or postoperative complications were compared between the 23-G and 25-G MIVS groups.
  
  
  RESULTS
  Both groups showed a statistically significant improvement in best-corrected visual acuity at postoperative 1, 3, and 6 months (All P < 0.05). Furthermore, the mean change of best-corrected visual acuity was not significantly different between the 2 groups at postoperative 1, 3, and 6 months (P = 0.208, P = 0.547, and P = 0.519, respectively), but 25-G MIVS group showed faster visual recovery than 23-G MIVS group at postoperative 1 day and at 1 week (P = 0.015, and P < 0.001, respectively). Severe hypotony of intraocular pressure less than 6 mmHg (3 eyes, 1.9%) or intraocular pressure elevation over 30 mmHg at postoperative 1 day (3 eyes, 1.9%) was found in the 23-G group, but not in the 25-G group, and was not statistically different between the groups (P = 0.553). More eyes required intraoperative suturing of sclerotomy sites in the 23-G group (18 eyes, 11.3%), whereas none of the eyes in the 25-G group needed suturing of sclerotomy (P < 0.002).
  
  
  CONCLUSIONS
  Both 23-G and 25-G MIVS yielded comparable visual outcomes for surgical treatment of idiopathic epiretinal membrane in pseudophakic eyes. The 25-G MIVS was associated with faster visual recovery and less postoperative hypotony than 23-G surgery.
authors.affiliation: *Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea; and †Institute of Vision Research, Department of Ophthalmology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Min
authors.initials: M
authors.lastname: Kim
authors.forename: Yong Sik
authors.initials: YS
authors.lastname: Park
authors.forename: Dong Hyun
authors.initials: DH
authors.lastname: Lee
authors.forename: Hyoung Jun
authors.initials: HJ
authors.lastname: Koh
authors.forename: Sung Chul
authors.initials: SC
authors.lastname: Lee
authors.forename: Sung Soo
authors.initials: SS
authors.lastname: Kim
mesh_terms: D000368:Aged; D019773:Epiretinal Membrane / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007431:Intraoperative Complications; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D011183:Postoperative Complications; D019591:Pseudophakia / Q000150:complications*; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy / Q000379:methods*