title: Renal assessment in teenage patients with cystic fibrosis - preliminary report.
abstract: BACKGROUND
  Together with increasing life expectancy of patients with cystic fibrosis *CF*, there is a growing need to deal with unforeseen problems and complications. Among others renal dysfunction has become of great concern.
  
  
  OBJECTIVE
  Evaluation of renal function in CF children.
  
  
  METHODS
  We performed cross-sectional study on a group of 11 teenage inpatients with CF. Physical examination, past medical history analysis, renal function measurements and analysis were conducted in all of them. Renal assessment included: serum cystatin C and creatinine levels, measured and estimated creatinine clearance, estimated cystatin C clearance, urine indicators of crystallization risk and renal ultrasonography.
  
  
  RESULTS
  One patient had elevated serum cystatin C level and diminished McIsaac equation. Renal ultrasound revealed non-congenital anomaly in 1 case - it was nephrolithiasis. All the individuals had elevated at least 1 urine indicator of crystallization risk.
  
  
  CONCLUSIONS
  There is a great need of good, standardized test of renal function in cystic fibrosis patients. The focus of research should turn towards finding a tool similar to faecal elastase, which is cheap, easy to perform, sensitive and specific, and can be used to confirm the diagnosis.
authors.affiliation: Cystic Fibrosis Centre, Institute of Mother and Child, Kasprzaka Street 17a, 01-211 Warsaw, Poland, e-mail: dorota.sands@imid.med.pl.
authors.forename: Dorota
authors.initials: D
authors.lastname: Sands
authors.forename: Joanna
authors.initials: J
authors.lastname: Jaworska
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Urzykowska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Ozimek
mesh_terms: D000293:Adolescent; D003430:Cross-Sectional Studies; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D053565:Hypercalciuria / Q000175:diagnosis / Q000209:etiology*; D007668:Kidney / Q000000981:diagnostic imaging*; D007674:Kidney Diseases / Q000175:diagnosis* / Q000209:etiology*; D007677:Kidney Function Tests; D008297:Male; D053040:Nephrolithiasis / Q000175:diagnosis / Q000209:etiology; D012372:ROC Curve; D014463:Ultrasonography