title: Pd(II) catalyzed ortho C-H iodination of phenylcarbamates at room temperature using cyclic hypervalent iodine reagents.
abstract: A novel approach to access ortho iodinated phenols using cyclic hypervalent iodine reagents through palladium(II) catalyzed C-H activation has been developed through weak coordination. The reaction showed excellent regioselectivity, reactivity and good functional group tolerance. A unique mechanism was proposed.
authors.affiliation: MOE Key Laboratory of Protein Sciences, Department of Pharmacology and Pharmaceutical Sciences, School of Medicine and School of Life Sciences, Tsinghua University, Beijing 100084, China. yrao@mail.tsinghua.edu.cn.
authors.forename: Xiuyun
authors.initials: X
authors.lastname: Sun
authors.forename: Xia
authors.initials: X
authors.lastname: Yao
authors.forename: Chao
authors.initials: C
authors.lastname: Zhang
authors.forename: Yu
authors.initials: Y
authors.lastname: Rao
mesh_terms: D054879:Halogenation; D007202:Indicators and Reagents / Q000737:chemistry; D007455:Iodine / Q000737:chemistry*; D007536:Isomerism; D010165:Palladium / Q000737:chemistry*; D048448:Phenylcarbamates / Q000737:chemistry*; D013696:Temperature
chemical_list: D007202:Indicators and Reagents; D048448:Phenylcarbamates; D010165:Palladium; D007455:Iodine