title: Simultaneous determination of four trace level endocrine disrupting compounds in environmental samples by solid-phase microextraction coupled with HPLC.
abstract: A simple, rapid, sensitive and effective method for the simultaneous determination of four endocrine disrupting compounds (EDCs) (bisphenol A (BPA), bisphenol F (BPF), bisphenol AF (BPAF) and bisphenol AP (BPAP)) in environment water samples based on solid-phase microextraction (SPME) coupled with high performance liquid chromatography (HPLC) was developed. Multi-wall carbon nanotubes (MWCNTs) adsorbents showed a good affinity to the target analytes. These compounds were rapidly extracted within 10 min. Various experimental parameters that could affect the extraction efficiencies had been investigated in detail. Under the optimum conditions, the enrichment factors of the method for the target EDCs were found to be 500. Satisfactory precision and accuracy of the method were obtained in a low concentration range of 2.0-500.0 ng mL(-1). The method detection limits were in the range of 0.10-0.30 ng mL(-1). The high pre-concentration rate and efficiency of the method ensure its successful application in extraction of trace EDCs from large volumes of environmental water samples. The extraction recoveries in real samples ranged from 85.3% to 102.5% with the relative standard deviations (n=5) less than 3.74%.
authors.affiliation: College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, Liaoning, People's Republic of China.
authors.forename: Lingling
authors.initials: L
authors.lastname: Wang
authors.affiliation: College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, Liaoning, People's Republic of China.
authors.forename: Zhenzhen
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, Liaoning, People's Republic of China.
authors.forename: Xu
authors.initials: X
authors.lastname: Xu
authors.affiliation: College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, Liaoning, People's Republic of China.
authors.forename: Danfeng
authors.initials: D
authors.lastname: Zhang
authors.affiliation: College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, Liaoning, People's Republic of China.
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.affiliation: College of Chemistry, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, Liaoning, People's Republic of China. Electronic address: zhanglei63@126.com.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000327:Adsorption; D001559:Benzhydryl Compounds / Q000032:analysis* / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D060766:Drinking Water / Q000032:analysis; D052244:Endocrine Disruptors / Q000032:analysis* / Q000737:chemistry; D037742:Nanotubes, Carbon / Q000737:chemistry; D010636:Phenols / Q000032:analysis* / Q000737:chemistry; D045483:Rivers / Q000737:chemistry; D052617:Solid Phase Microextraction; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000737:chemistry
chemical_list: D001559:Benzhydryl Compounds; D060766:Drinking Water; D052244:Endocrine Disruptors; D037742:Nanotubes, Carbon; D010636:Phenols; D014874:Water Pollutants, Chemical
keywords: Endocrine disrupting compounds; Environment water samples; High performance liquid chromatography.; Multi-walled carbon nanotubes; Solid-phase microextraction