title: Thermally Switched Release from a Nanogel-in-Microfiber Device.
abstract: A nanogel-in-microfiber device, whose release can be switched on and off in response to a temperature change, is successfully developed. The release behaviors are realized through the deswelling and swelling of the nanogels in shell layer of fiber by alternatively elevating and lowering the environmental temperature.
authors.affiliation: School of Materials Science and Engineering, Key Laboratory of Advanced Technologies of Material, Minister of Education, Southwest Jiaotong University, Chengdu, 610031, P. R. China.
authors.forename: Long
authors.initials: L
authors.lastname: Li
authors.affiliation: School of Materials Science and Engineering, Key Laboratory of Advanced Technologies of Material, Minister of Education, Southwest Jiaotong University, Chengdu, 610031, P. R. China.
authors.forename: Guang
authors.initials: G
authors.lastname: Yang
authors.affiliation: School of Mechanical Engineering, Southwest Jiaotong University, Chengdu, 610031, P. R. China.
authors.forename: Guangliang
authors.initials: G
authors.lastname: Zhou
authors.affiliation: School of Materials Science and Engineering, Key Laboratory of Advanced Technologies of Material, Minister of Education, Southwest Jiaotong University, Chengdu, 610031, P. R. China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: School of Materials Science and Engineering, Key Laboratory of Advanced Technologies of Material, Minister of Education, Southwest Jiaotong University, Chengdu, 610031, P. R. China.
authors.forename: Xiaotong
authors.initials: X
authors.lastname: Zheng
authors.affiliation: School of Materials Science and Engineering, Key Laboratory of Advanced Technologies of Material, Minister of Education, Southwest Jiaotong University, Chengdu, 610031, P. R. China.
authors.forename: Shaobing
authors.initials: S
authors.lastname: Zhou
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000633:toxicity; D001391:Azo Compounds / Q000737:chemistry; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004317:Doxorubicin / Q000737:chemistry / Q000633:toxicity; D004337:Drug Carriers / Q000737:chemistry; D051379:Mice; D000080385:Nanogels; D011092:Polyethylene Glycols / Q000737:chemistry*; D011094:Polyethyleneimine / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D013696:Temperature
chemical_list: D000903:Antibiotics, Antineoplastic; D001391:Azo Compounds; D004337:Drug Carriers; D000080385:Nanogels; D011108:Polymers; C413692:polyethylene glycol polyethyleneimine nanogel; D011092:Polyethylene Glycols; C100258:methyl orange; D004317:Doxorubicin; D011094:Polyethyleneimine
keywords: cancer therapy; core-shell; nanogels; on-demand release; temperature responsiveness