title: Scorpion sting nephropathy.
abstract: Scorpion envenomations are ubiquitous, but nephropathy is a rare manifestation, reported mainly from the Middle East and North Africa. Rapid venom redistribution from blood, delayed excretion from the kidneys, direct toxicity of venom enzymes, cytokine release and afferent arteriolar constriction have been seen in experimental animals. Haemoglobinuria, acute tubular necrosis, interstitial nephritis and haemolytic-uraemic syndrome have been documented in human victims of scorpion envenomation. Epidemiology, venom components and toxins, effects on the laboratory mammals especially the kidneys and reports of renal failure in humans are reviewed in this article.
authors.affiliation: Department of Internal Medicine, Pondicherry Institute of Medical Sciences, Kalapet, Pondicherry, India.
authors.forename: Stalin
authors.initials: S
authors.lastname: Viswanathan
authors.affiliation: Department of Nephrology, Pondicherry Institute of Medical Sciences, Kalapet, Pondicherry, India.
authors.forename: Chaitanya
authors.initials: C
authors.lastname: Prabhu
keywords: kidney; renal failure; scorpion envenomation; scorpion sting; venom