title: A supramolecular approach to improve the gene transfection efficacy of dendrimers.
abstract: Cyanuric acid is able to form complementary hydrogen bonds with melamine. Here, the specific recognition between cyanuric acid and melamine is used to significantly improve the gene transfection efficacy of low generation dendrimers via a supramolecular approach.
authors.affiliation: Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences, East China Normal University, Shanghai, 200241, P. R. China. yycheng@mail.ustc.edu.cn.
authors.forename: Naimin
authors.initials: N
authors.lastname: Shao
authors.forename: Tianjiao
authors.initials: T
authors.lastname: Dai
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Yiyun
authors.initials: Y
authors.lastname: Cheng
mesh_terms: D002470:Cell Survival / Q000187:drug effects; D050091:Dendrimers / Q000737:chemistry* / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D018014:Gene Transfer Techniques; D057809:HEK293 Cells; D006801:Humans; D006860:Hydrogen Bonding; D015394:Molecular Structure; D014227:Triazines / Q000737:chemistry*
chemical_list: D050091:Dendrimers; D014227:Triazines; C004632:cyanuric acid; C011907:melamine