title: HTT/Huntingtin in selective autophagy and Huntington disease: A foe or a friend within?
authors.affiliation: a Center for Metabolic and Degenerative Diseases; The Brown Foundation Institute of Molecular Medicine; The University of Texas Medical School at Houston ; Houston , TX , USA.
authors.forename: Yan-Ning
authors.initials: YN
authors.lastname: Rui
authors.forename: Zhen
authors.initials: Z
authors.lastname: Xu
authors.forename: Bindi
authors.initials: B
authors.lastname: Patel
authors.forename: Ana Maria
authors.initials: AM
authors.lastname: Cuervo
authors.forename: Sheng
authors.initials: S
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001343:Autophagy; D004331:Drosophila melanogaster / Q000378:metabolism; D006801:Humans; D006816:Huntington Disease / Q000378:metabolism* / Q000473:pathology*; D051379:Mice; D008954:Models, Biological; D009419:Nerve Tissue Proteins / Q000378:metabolism*
chemical_list: D009419:Nerve Tissue Proteins
keywords: ATG101, autophagy-related 101; ATG13, autophagy-related 13; Huntingtin; Huntington disease; KO, knockout; MAP1LC3A, microtubule-associated protein 1 light chain 3 alpha; MAPT/Tau, microtubule-associated protein tau; MTOR, mechanistic target of rapamycin (serine/threonine kinase); MTORC1; MTORC1, MTOR complex 1; PRKAA/AMPK, protein kinase, AMP-activated, α catalytic subunit; RB1CC1, RB1-inducible coiled-coil 1; SQSTM1, sequestosome 1; SQSTM1/p62; ULK1; ULK1, unc-51 like autophagy activating kinase 1.; aggrephagy; cargo recognition; lipophagy; mitophagy; nonselective autophagy; selective autophagy