title: How Ebola has been evolving in West Africa.
abstract: The ongoing Ebola outbreak in West Africa has generated fears of a global epidemic. Particularly, estimates of higher substitution rates have raised concerns about increased transmissibility or virulence. A recent study using a more comprehensive datasets demonstrates lower variation, highlighting the importance of representative datasets and limitations of computational modelling.
authors.affiliation: Key Laboratory of Etiology and Biosafety for Emerging and Highly Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
authors.forename: Si-Qing
authors.initials: SQ
authors.lastname: Liu
authors.affiliation: Key Laboratory of Etiology and Biosafety for Emerging and Highly Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
authors.forename: Simon
authors.initials: S
authors.lastname: Rayner
authors.affiliation: Key Laboratory of Etiology and Biosafety for Emerging and Highly Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. Electronic address: zhangbo@wh.iov.cn.
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
mesh_terms: D029043:Ebolavirus / Q000235:genetics*; D019142:Hemorrhagic Fever, Ebola / Q000821:virology*; D006801:Humans; D059645:Mutation Rate
keywords: Ebola; West Africa; evolution; low variation; nucleotide substitutions rate