title: Precursor T-lymphoblastic lymphoma presenting as primary renal lymphoma with acute renal failure.
abstract: We report a case of acute renal failure (ARF) and bilateral nephromegaly in a patient with a history of Crohn's disease and treatment with azathioprine. Kidney biopsy revealed diffuse renal infiltration by precursor T-cell lymphoblastic lymphoma (T-LBL). At the time of diagnosis, no extrarenal manifestations of the lymphoma were detectable and therefore the lymphoma was categorized as primary renal lymphoma (PRL). Thus far, precursor T-LBL presenting as PRL has not been described before. We emphasize that in patients with ARF and bilateral renal enlargement, renal lymphoma is an important differential diagnostic consideration.
authors.affiliation: Department of Medicine, Division of Nephrology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Arjan J
authors.initials: AJ
authors.lastname: Kwakernaak
authors.affiliation: Department of Medicine, Division of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Mette D
authors.initials: MD
authors.lastname: Hazenberg
authors.affiliation: Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Joris J T H
authors.initials: JJ
authors.lastname: Roelofs
authors.affiliation: Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Carel J M
authors.initials: CJ
authors.lastname: van Noesel
authors.affiliation: Department of Medicine, Division of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Marinus H J
authors.initials: MH
authors.lastname: van Oers
authors.affiliation: Department of Medicine, Division of Nephrology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Anne
authors.initials: A
authors.lastname: van Tellingen
keywords: (primary) renal lymphoma; acute renal failure; bilateral nephromegaly; precursor T-lymphoblastic lymphoma