title: Germinal center quality control: death by Fas.
abstract: Fas is a cell surface death receptor critical for immune regulation. In this issue of Immunity, Butt et al. (2015) show that Fas eliminates B cells that have become uncoupled from positive and negative selection in the germinal center.
authors.affiliation: Department of Anatomy, Cardiovascular Research Institute, and Sandler Asthma Basic Research Center, University of California, San Francisco, San Francisco, CA, USA. Electronic address: chris.allen@ucsf.edu.
authors.forename: Christopher D C
authors.initials: CD
authors.lastname: Allen
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000276:immunology*; D001402:B-Lymphocytes / Q000166:cytology*; D018858:Germinal Center / Q000166:cytology* / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D019014:fas Receptor / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D019014:fas Receptor; D007073:Immunoglobulin E