title: Detection of microRNA SNPs with ultrahigh specificity by using reduced graphene oxide-assisted rolling circle amplification.
abstract: Here we report a reduced graphene oxide-assisted rolling circle amplification for the detection of miRNA SNPs. The difference of the signal of a miRNA SNP reaches 100 fold, a value over 10 times larger than some current methodologies, which allows the discrimination of a SNP even with the naked eye.
authors.affiliation: Laboratory of Biosensing Technology, School of Life Sciences, Shanghai University, Shanghai 200444, P. R. China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Zhu
authors.forename: Yalan
authors.initials: Y
authors.lastname: Shen
authors.forename: Jiepei
authors.initials: J
authors.lastname: Cao
authors.forename: Li
authors.initials: L
authors.lastname: Yin
authors.forename: Fangfang
authors.initials: F
authors.lastname: Ban
authors.forename: Yongqian
authors.initials: Y
authors.lastname: Shu
authors.forename: Genxi
authors.initials: G
authors.lastname: Li
mesh_terms: D006108:Graphite / Q000737:chemistry*; D006801:Humans; D035683:MicroRNAs / Q000235:genetics*; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry*; D020641:Polymorphism, Single Nucleotide; D013050:Spectrometry, Fluorescence
chemical_list: D035683:MicroRNAs; D010087:Oxides; D006108:Graphite