title: Unilateral testicular metastasis of low PSA level prostatic adenocarcinoma.
abstract: A 71-year-old man presented with a firm left testicle 15 years after being diagnosed with prostatic adenocarcinoma. After the initial diagnosis, the patient underwent a radical prostatectomy. He received radiation therapy 5 years after surgery for a slightly elevated prostate-specific antigen (PSA) level and a negative metastatic workup. Eight years later, the patient's PSA rose to 3.38 ng/mL and he was started on intermittent Lupron therapy. It was then 3 years later when the patient discovered the testicular mass. At that time, his PSA level was 2.98 ng/mL. He underwent a left orchiectomy which demonstrated metastatic prostatic adenocarcinoma. Currently, the patient is doing well 3 months postorchiectomy and is now receiving continuous testosterone suppression therapy. This case report discusses the unique modes of spread from the prostate to the testicle as well as the importance of follow-up care in patients with prostate cancer, especially in the setting of low PSA levels.
authors.affiliation: The Commonwealth Medical College, Scranton, Pennsylvania, USA.
authors.forename: Brianna Jeanette
authors.initials: BJ
authors.lastname: Shinn
authors.affiliation: Medical Oncology Associates, Kingston, Pennsylvania, USA.
authors.forename: David W
authors.initials: DW
authors.lastname: Greenwald
authors.affiliation: Department of Pathology, Wilkes Barre General Hospital, Wilkes Barre, Pennsylvania, USA.
authors.forename: Navid
authors.initials: N
authors.lastname: Ahmad
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D006801:Humans; D008297:Male; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D013736:Testicular Neoplasms / Q000556:secondary* / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen