title: Thymic selection: to thine own self be true.
abstract: It has been shown that self-reactive T cells can be detected in the periphery. In this issue of Immunity, Yu et al. (2015) show that clonal deletion prunes the T cell repertoire but does not eliminate self-reactive T cell clones.
authors.affiliation: Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Kitz
authors.affiliation: Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA. Electronic address: david.hafler@yale.edu.
authors.forename: David A
authors.initials: DA
authors.lastname: Hafler
mesh_terms: D000818:Animals; D018414:CD8-Positive T-Lymphocytes / Q000166:cytology* / Q000276:immunology*; D017637:Clonal Deletion; D005260:Female; D006801:Humans; D008297:Male