title: Biomarkers in the ontology for general medical science.
abstract: A great deal of recent work has been devoted to the topic of biomarkers as aids to diagnosis, prognosis and treatment evaluation. Basing our work on the Ontology for General Medical Science (OGMS) and on the specifications provided by the Institute of Medicine (IOM), we propose definitions for biomarkers of various types. These definitions provide a formal representation of what biomarkers are in a way that allows us to remove certain ambiguities and inconsistencies in the documentation provided by the IOM.
authors.affiliation: Department of Biomedical Informatics, University at Buffalo, NY, USA.
authors.forename: Werner
authors.initials: W
authors.lastname: Ceusters
authors.affiliation: Department of Philosophy, University at Buffalo, NY, USA.
authors.forename: Barry
authors.initials: B
authors.lastname: Smith
mesh_terms: D064229:Biological Ontologies; D015415:Biomarkers; D020000:Decision Support Systems, Clinical / Q000145:classification; D057286:Electronic Health Records / Q000145:classification*; D016247:Information Storage and Retrieval / Q000379:methods*; D009323:Natural Language Processing; D009626:Terminology as Topic; D014481:United States
chemical_list: D015415:Biomarkers