title: Combined magnetic resonance imaging approach for the assessment of in vivo knee joint kinematics under full weight-bearing conditions.
abstract: The development of detailed and specific knowledge on the biomechanical behavior of loaded knee structures has received increased attention in recent years. Stress magnetic resonance imaging techniques have been introduced in previous work to study knee kinematics under load conditions. Previous studies captured the knee movement either in atypical loading supine positions, or in upright positions with help of inclined supporting backrests being insufficient for movement capture under full-body weight-bearing conditions. In this work, we used a combined magnetic resonance imaging approach for measurement and assessment in knee kinematics under full-body weight-bearing in single legged stance. The proposed method is based on registration of high-resolution static magnetic resonance imaging data acquired in supine position with low-resolution data, quasi-static upright-magnetic resonance imaging data acquired in loaded positions for different degrees of knee flexion. The proposed method was applied for the measurement of tibiofemoral kinematics in 10 healthy volunteers. The combined magnetic resonance imaging approach allows the non-invasive measurement of knee kinematics in single legged stance and under physiological loading conditions. We believe that this method can provide enhanced understanding of the loaded knee kinematics.
authors.affiliation: Helmholtz-Institute for Biomedical Engineering of the RWTH Aachen University, Aachen, Germany alhares@hia.rwth-aachen.de.
authors.forename: Ghaith
authors.initials: G
authors.lastname: Al Hares
authors.affiliation: Helmholtz-Institute for Biomedical Engineering of the RWTH Aachen University, Aachen, Germany Department for Orthopedic Surgery, University Hospital Aachen, Aachen, Germany.
authors.forename: Jörg
authors.initials: J
authors.lastname: Eschweiler
authors.affiliation: Helmholtz-Institute for Biomedical Engineering of the RWTH Aachen University, Aachen, Germany.
authors.forename: Klaus
authors.initials: K
authors.lastname: Radermacher
mesh_terms: D000328:Adult; D019645:Arthroplasty, Replacement, Knee; D001696:Biomechanical Phenomena / Q000502:physiology*; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D007719:Knee Joint / Q000502:physiology*; D035002:Lower Extremity / Q000502:physiology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D016059:Range of Motion, Articular; D016474:Weight-Bearing / Q000502:physiology*
keywords: Kinematics; magnetic resonance imaging; total knee arthroplasty; total knee replacement; weight-bearing