title: Pulmonary veno-occlusive disease associated with hypertrophic cardiomyopathy.
abstract: An autopsy analysis of the lung findings in 14 cases of hypertrophic cardiomyopathy (HCM) was undertaken, with particular attention paid to the pulmonary vessels. Six of the 14 cases of HCM showed histological features of pulmonary veno-occlusive disease (PVOD). The coexistence of these two rare conditions appears to be more than a chance association. In view of recent advances in the understanding of the genetic basis for HCM, genetic analysis of patients with PVOD should be performed in order to determine whether there may be a common genetic context for the coexistence of these disorders.
authors.affiliation: Department of Anatomical Pathology, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
authors.forename: R
authors.initials: R
authors.lastname: Chetty
authors.affiliation: Department of Anatomical Pathology, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
authors.forename: A G
authors.initials: AG
authors.lastname: Rose
authors.affiliation: Department of Medicine (Cardiac Clinic), University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa; Department of Anatomical Pathology, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
authors.forename: P J
authors.initials: PJ
authors.lastname: Commerford
authors.affiliation: Department of Anatomical Pathology, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
authors.forename: D A
authors.initials: DA
authors.lastname: Taylor