title: Validation of the Chinese version of the Neurological Disorders Depression Inventory for Epilepsy (C-NDDI-E) in West China.
abstract: OBJECTIVE
  We aimed to validate the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) for Chinese people with epilepsy (PWE).
  
  
  METHODS
  The NDDI-E was translated into a Chinese version. A consecutive cohort of PWE from West China Hospital was recruited to test the reliability and validity of the Chinese version of the NDDI-E (C-NDDI-E). Each patient underwent the Mini International Neuropsychiatric Interview (MINI) and C-NDDI-E.
  
  
  RESULTS
  A total of 202 PWE completed the psychiatric evaluation. The C-NDDI-E was easily comprehended and quickly completed by all participants. Fifty-four patients (26.7%) had current major depressive disorder (MDD) according to the MINI criteria. The Cronbach's α coefficient for the C-NDDI-E was 0.825. Receiver operating characteristic analyses showed an area under the curve of 0.936 (95% CI=0.904-0.968). At a cutoff score of >12, the C-NDDI-E had a sensitivity of 0.926, a specificity of 0.804, a positive predictive value of 0.633, and a negative predictive value of 0.967.
  
  
  CONCLUSIONS
  The C-NDDI-E is a valuable instrument for screening MDD in Chinese PWE.
authors.affiliation: Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: saratx@163.com.
authors.forename: Xin
authors.initials: X
authors.lastname: Tong
authors.affiliation: Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: andongmei2010@gmail.com.
authors.forename: Dongmei
authors.initials: D
authors.lastname: An
authors.affiliation: Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, PR China. Electronic address: lllxiya@126.com.
authors.forename: Lili
authors.initials: L
authors.lastname: Lan
authors.affiliation: Department of Psychiatry, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: zhouxiaobo19861986@163.com.
authors.forename: Xiaobo
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: qinqin198@163.com.
authors.forename: Qin
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: fenglaixiao@gmail.com.
authors.forename: Fenglai
authors.initials: F
authors.lastname: Xiao
authors.affiliation: Department of Neurology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea. Electronic address: sppark@knu.ac.kr.
authors.forename: Sung-Pa
authors.initials: SP
authors.lastname: Park
authors.affiliation: Department of Neuropsychiatry, School of Medicine, Aichi Medical University, Nagakute, Japan. Electronic address: fwkh2919@mb.infoweb.ne.jp.
authors.forename: Kousuke
authors.initials: K
authors.lastname: Kanemoto
authors.affiliation: Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA. Electronic address: a.kanner@med.miami.edu.
authors.forename: Andres M
authors.initials: AM
authors.lastname: Kanner
authors.affiliation: Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. Electronic address: zhoudong66@yahoo.de.
authors.forename: Dong
authors.initials: D
authors.lastname: Zhou
mesh_terms: D000328:Adult; D044466:Asian People / Q000208:ethnology / Q000523:psychology; D002681:China; D003863:Depression / Q000175:diagnosis* / Q000208:ethnology / Q000523:psychology; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000208:ethnology / Q000523:psychology; D004827:Epilepsy / Q000175:diagnosis* / Q000208:ethnology / Q000523:psychology; D005260:Female; D006761:Hospitals; D006801:Humans; D007802:Language; D008297:Male; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000208:ethnology / Q000523:psychology; D009483:Neuropsychological Tests; D010555:Personality Inventory / Q000592:standards; D011569:Psychiatric Status Rating Scales / Q000592:standards*; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014175:Translating
keywords: China; Depression; Epilepsy; NDDI-E; Validation