title: [Risky factors in ovarian cancer (our and foreign experience)].
abstract: OBJECTIVE
  Our aim was to summarize our and foreign experience and evaluate and research the most common risky factors for development of ovarian cancer. In this way we wanted to summarize also the prevanantive factors for ovarian cancer.
  
  
  METHODS
  We researched for 10 years period patients with ovarian cancer (2000 patients). The most common risky factors were examined and researched.
  
  
  RESULTS
  All patients with ovarian, tube and peritoneall cancer--must be tested for BRCA 1 and BRCA2 gene mutations. The patients who want to preserve their reproductive functions orto postpone the preventive surgery, have to go through 6 months screening by TVS. The patients with Lynch Syndrome are advised for prophylactic salpingoophorectomy or hysterectomy. When there was a high risk the patients are advised to take oral contraceptives before family planning.
  
  
  CONCLUSIONS
  Nevertheless these results future research and clinical trials will give additional light in this field.
authors.forename: S
authors.initials: S
authors.lastname: Ivanov
mesh_terms: D019313:BRCA1 Protein / Q000235:genetics; D024682:BRCA2 Protein / Q000235:genetics; D002031:Bulgaria / Q000453:epidemiology; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology / Q000517:prevention & control; D010053:Ovary / Q000378:metabolism / Q000473:pathology; D012307:Risk Factors
chemical_list: D019313:BRCA1 Protein; D024682:BRCA2 Protein