title: Extracorporeal life support for massive pulmonary embolism during pregnancy.
abstract: Massive pulmonary embolism is a leading cause of death during pregnancy. While the prevention of thromboembolic disease during the peripartum period is codified, there is no consensus regarding its treatment. We report two cases of pregnant women who had massive pulmonary embolisms (PE) and shock treated with veno-arterial extracorporeal life support (ECLS) and heparin therapy.Haemodynamic and oxygenation parameters were rapidly restored. The patients completely recovered and the pregnancies continued. The patients did not develop pulmonary hypertension. ECLS can be considered as a successful treatment option of massive pulmonary embolism during pregnancy.
authors.affiliation: Grenoble University Hospital and University of Grenoble, Grenoble, France abataillard@chu-grenoble.fr.
authors.forename: A
authors.initials: A
authors.lastname: Bataillard
authors.affiliation: Grenoble University Hospital and University of Grenoble, Grenoble, France.
authors.forename: A
authors.initials: A
authors.lastname: Hebrard
authors.affiliation: Grenoble University Hospital and University of Grenoble, Grenoble, France.
authors.forename: L
authors.initials: L
authors.lastname: Gaide-Chevronnay
authors.affiliation: Grenoble University Hospital and University of Grenoble, Grenoble, France.
authors.forename: M
authors.initials: M
authors.lastname: Casez
authors.affiliation: Grenoble University Hospital and University of Grenoble, Grenoble, France.
authors.forename: G
authors.initials: G
authors.lastname: Dessertaine
authors.affiliation: Grenoble University Hospital and University of Grenoble, Grenoble, France.
authors.forename: M
authors.initials: M
authors.lastname: Durand
authors.affiliation: Grenoble University Hospital and University of Grenoble, Grenoble, France.
authors.forename: O
authors.initials: O
authors.lastname: Chavanon
authors.affiliation: Grenoble University Hospital and University of Grenoble, Grenoble, France.
authors.forename: P
authors.initials: P
authors.lastname: Albaladejo
mesh_terms: D000328:Adult; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D008021:Life Support Systems; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000503:physiopathology / Q000628:therapy; D011655:Pulmonary Embolism / Q000097:blood / Q000503:physiopathology / Q000628:therapy
chemical_list: D006493:Heparin
keywords: extracorporeal life support; pregnancy; pulmonary embolism; thrombolysis; vital distress