title: Fully automated production of sodium [(18)F]fluoride on AllInOne and miniAllInOne synthesizers.
abstract: A fully automated production of the imaging agent sodium [(18)F]fluoride ([(18)F]NaF) on two different modules commercialized by Trasis®, the AllInOne and the miniAllInOne, is reported. Both modules allow to prepare [(18)F]NaF in good radiochemical yield (around 97%) in less than 4min with the same specifications. Quality control of [(18)F]NaF produced by this way was performed according to the US and European Pharmacopeia monograph requirements.
authors.affiliation: NancycloTEP, Plateforme d'imagerie expérimentale, F-54500 Vandoeuvre les Nancy, France; Université de Lorraine, F-54500 Vandoeuvre les Nancy, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Collet
authors.affiliation: TRASIS SA, rue Gilles Magnée 90, 4430 Ans, Belgium.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Otabashi
authors.affiliation: Cyclotron Research Centre, University of Liège, 4000 Liège, Belgium.
authors.forename: Fabrice
authors.initials: F
authors.lastname: Giacomelli
authors.affiliation: NancycloTEP, Plateforme d'imagerie expérimentale, F-54500 Vandoeuvre les Nancy, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Veran
authors.affiliation: NancycloTEP, Plateforme d'imagerie expérimentale, F-54500 Vandoeuvre les Nancy, France; Université de Lorraine, F-54500 Vandoeuvre les Nancy, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Karcher
authors.affiliation: NancycloTEP, Plateforme d'imagerie expérimentale, F-54500 Vandoeuvre les Nancy, France; Université de Lorraine, F-54500 Vandoeuvre les Nancy, France; CNRS, UMR 7565, F-54506 Vandoeuvre les Nancy, France.
authors.forename: Yves
authors.initials: Y
authors.lastname: Chapleur
authors.affiliation: Université de Lorraine, F-54500 Vandoeuvre les Nancy, France; CNRS, UMR 7565, F-54506 Vandoeuvre les Nancy, France. Electronic address: sandrine.langle@univ-lorraine.fr.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Lamandé-Langle
mesh_terms: D005462:Fluorine Radioisotopes / Q000737:chemistry*; D012969:Sodium Fluoride / Q000138:chemical synthesis*
chemical_list: D005462:Fluorine Radioisotopes; D012969:Sodium Fluoride
keywords: Positron emission tomography; Radiopharmaceutical; Sodium [18F]fluoride; [18F]NaF