title: [Relationship between endometriosis stage, characteristics of enodmetriotic lesions and severity of dysmenorrhoea].
abstract: OBJECTIVE
  To explore the association between endometriosis stage, characteristics of endometriotic lesions and severity of dysmenorrhoea.
  
  
  METHODS
  The clinical data were collected from 140 patients with laparoscopically diagnosed endometriosis between May 2013 and December 2013. They were scored by visual analogue scale (VAS) according to their preoperative dysmenorrhoea. Endometriotic lesions were recorded by their anatomical distributions. And endometriosis was staged and scored according to the score of Revised American Fertility Society (r-AFS). The relationship between dysmenorrhoea and endometriosis stage as well as endometriotic foci was analyzed. Chi-square test and Logistic regression were used for statistical analyses.
  
  
  RESULTS
  Among them, there were 95 (67.86%) patients with dysmenorrhoea and 45(32.14%) without dysmenorrhoea. No significant inter-group difference existed in age (P > 0.05). The interval from menarche to the onset of dysmenorrhoea was (8 ± 9) years and duration of dysmenorrhoea (2.3 ± 1.5) days each month. A correlation existed between endometriosis stage and severity of dysmenorrhoea (χ² = 20.677, P < 0.05). A strong association was found between posterior cul-de-sac obliteration and severity of dysmenorrhoea (χ² = 8.471, P < 0.05). No significant difference was found for ovarian endometriomas, ovarian adhesion, superficial peritoneal lesions and deep infiltrating endometriosis in non- and minimal dysmenorrhoea groups with moderate and severe dysmenorrhoea (P > 0.05). Posterior cul-de-sac obliteration was an independent influencing factor for dysmenorrhoea. The odds ratio (OR) was 3.291 and 95% confidence interval (CI) 1.453-7.454. However, no relevance existed between ovarian endometriomas and dysmenorrhoea by Logistic analysis.
  
  
  CONCLUSIONS
  The severity of dysmenorrhoea has close correlation with posterior cul-de-sac obliteration. However, there is a weak relevance with ovarian endometreaiomas.
authors.affiliation: Department of Obstetrics and Gynecology, the Zhongshan Hospital of Xiamen University, Xiamen 361004, China.
authors.forename: Mingzhu
authors.initials: M
authors.lastname: Ye
authors.affiliation: Email: Bysy19681229@163.com.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Guo
authors.forename: Jinsong
authors.initials: J
authors.lastname: Han
authors.forename: Haojie
authors.initials: H
authors.lastname: He
authors.forename: Kun
authors.initials: K
authors.lastname: Zhang
authors.forename: Guangwu
authors.initials: G
authors.lastname: Xiong
authors.forename: Yan
authors.initials: Y
authors.lastname: Yang
mesh_terms: D004412:Dysmenorrhea; D004715:Endometriosis; D005260:Female; D006801:Humans; D010535:Laparoscopy; D016015:Logistic Models; D010147:Pain Measurement; D012720:Severity of Illness Index; D000267:Tissue Adhesions