title: The role of cardiovascular magnetic resonance in sudden death risk stratification in hypertrophic cardiomyopathy.
abstract: Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden death in young patients, but current risk stratification strategies do not identify all patients at risk. Contrast-enhanced cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) can identify areas of abnormal myocardial substrate comprising fibrosis, the structural nidus for potentially life-threatening ventricular arrhythmias. More recently, follow-up studies have demonstrated a strong relationship between extent of LGE in patients with HCM and increased risk of adverse disease-related events, including sudden death.
authors.affiliation: Division of Cardiology, Hypertrophic Cardiomyopathy Center, Tufts Medical Center, #70, 800 Washington Street, Boston, MA 02111, USA. Electronic address: mmaron@tuftsmedicalcenter.org.
authors.forename: Martin S
authors.initials: MS
authors.lastname: Maron
mesh_terms: D002312:Cardiomyopathy, Hypertrophic; D016757:Death, Sudden, Cardiac; D004719:Endomyocardial Fibrosis; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine
keywords: Cardiovascular magnetic resonance; Hypertrophic cardiomyopathy; Late gadolinium enhancement; Myocardial fibrosis; Sudden death