title: Aerobic interval exercise with an eccentric contraction induces muscular hypertrophy and augmentation of muscular strength in rats.
abstract: [Purpose] The purpose of this study was to examine whether an aerobic interval exercise using an eccentric contraction would result in skeletal muscular hypertrophy and augmentation of muscular strength in rats. [Subjects and Methods] Twenty-one female Wistar rats were used in this study. The rats were randomly divided into three groups. The control group performed no exercise. The aerobic endurance exercise group ran for 90 min. The aerobic interval exercise group ran for a total of 90 minutes in 5 minute bouts separated by 2 minute rest periods. The exercise groups ran on a downhill treadmill incline, once every three days, for a total of twenty sessions. [Results] The muscle wet weights, the muscle fiber cross-section minor axes, and the tetanus tension results of the aerobic endurance and aerobic interval exercise groups were significantly larger than those of the control group. [Conclusion] These results indicate that aerobic interval exercise may be an effective method of inducing hypertrophy and augmenting muscular strength in skeletal muscle.
authors.affiliation: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan ; Program in Biological System Sciences, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Japan ; University Medical Center, Prefectural University of Hiroshima, Japan.
authors.forename: Wakako
authors.initials: W
authors.lastname: Tsumiyama
authors.affiliation: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan ; Program in Biological System Sciences, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Japan ; University Medical Center, Prefectural University of Hiroshima, Japan.
authors.forename: Sadaaki
authors.initials: S
authors.lastname: Oki
authors.affiliation: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan ; University Medical Center, Prefectural University of Hiroshima, Japan.
authors.forename: Naomi
authors.initials: N
authors.lastname: Takamiya
authors.affiliation: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan ; University Medical Center, Prefectural University of Hiroshima, Japan.
authors.forename: Namiko
authors.initials: N
authors.lastname: Umei
authors.affiliation: University Medical Center, Prefectural University of Hiroshima, Japan.
authors.forename: Michele Eisemann
authors.initials: ME
authors.lastname: Shimizu
authors.affiliation: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan ; Program in Biological System Sciences, Graduate School of Comprehensive Scientific Research, Prefectural University of Hiroshima, Japan ; University Medical Center, Prefectural University of Hiroshima, Japan.
authors.forename: Takeya
authors.initials: T
authors.lastname: Ono
authors.affiliation: Department of Physical Therapy, Faculty of Health and Welfare, Prefectural University of Hiroshima, Japan ; University Medical Center, Prefectural University of Hiroshima, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Otsuka
keywords: Aerobic interval exercise; Augmentation of muscular strength; Muscular hypertrophy