title: Improving coronary artery bypass graft durability: use of the external saphenous vein graft support.
abstract: Coronary bypass grafting remains the best option for patients suffering from multivessel coronary artery disease, and the saphenous vein is used as an additional conduit for multiple complete revascularizations. However, the long-term vein graft durability is poor, with almost 75% of occluded grafts after 10 years. To improve the durability, the concept of an external supportive structure was successfully developed during the last years: the eSVS Mesh device (Kips Bay Medical) is an external support for vein graft made of weft-knitted nitinol wire into a tubular form with an approximate length of 24 cm and available in three diameters (3.5, 4.0 and 4.5 mm). The device is placed over the outer wall of the vein and carefully deployed to cover the full length of the graft. The mesh is flexible for full adaptability to the heart anatomy and is intended to prevent kinking and dilatation of the vein in addition to suppressing the intima hyperplasia induced by the systemic blood pressure. The device is designed to reduce the vein diameter of about 15-20% at most to prevent the vein radial expansion induced by the arterial blood pressure, and the intima hyperplasia leading to the graft failure. We describe the surgical technique for preparing the vein graft with the external saphenous vein graft support (eSVS Mesh) and we share our preliminary clinical results.
authors.affiliation: Cardiac Surgery Unit, University Hospital of Lausanne, Lausanne, Switzerland Cardiovascular Research Unit, University Hospital of Lausanne, Lausanne, Switzerland enricoferrari@bluewin.ch.
authors.forename: Enrico
authors.initials: E
authors.lastname: Ferrari
authors.affiliation: Cardiovascular Research Unit, University Hospital of Lausanne, Lausanne, Switzerland.
authors.forename: Ludwig
authors.initials: L
authors.lastname: von Segesser
authors.affiliation: Cardiovascular Research Unit, University Hospital of Lausanne, Lausanne, Switzerland.
authors.forename: Denis
authors.initials: D
authors.lastname: Berdajs
mesh_terms: D000368:Aged; D000497:Alloys; D000714:Anastomosis, Surgical; D001026:Coronary Artery Bypass / Q000295:instrumentation*; D003324:Coronary Artery Disease / Q000601:surgery*; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012501:Saphenous Vein / Q000637:transplantation*; D015607:Stents; D013526:Surgical Mesh; D016896:Treatment Outcome; D014654:Vascular Patency
chemical_list: D000497:Alloys; C013616:nitinol
keywords: Coronary artery bypass grafting; Great saphenous vein; Myocardial revascularization