title: Copper(II)-Catalyzed Direct Sulfonylation of C(sp(2))-H Bonds with Sodium Sulfinates.
abstract: A copper-catalyzed direct sulfonylation of C(sp(2))-H bonds with sodium sulfinates using a removable directing group is described. This reaction tolerates a wide range of functional groups, providing an efficient protocol for the synthesis of diverse aryl sulfones. Moreover, a series of 2,6-disubstituted benzamides could be synthesized via sequential C-H functionalization.
authors.affiliation: Department of Chemistry, Zhejiang University, Hangzhou 310027, China.
authors.forename: Wei-Hao
authors.initials: WH
authors.lastname: Rao
authors.affiliation: Department of Chemistry, Zhejiang University, Hangzhou 310027, China.
authors.forename: Bing-Feng
authors.initials: BF
authors.lastname: Shi
mesh_terms: D001549:Benzamides / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006860:Hydrogen Bonding; D007477:Ions / Q000737:chemistry*; D015394:Molecular Structure; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry; D013452:Sulfonium Compounds / Q000737:chemistry*
chemical_list: D001549:Benzamides; D007477:Ions; D013450:Sulfones; D013452:Sulfonium Compounds; D003300:Copper