title: Intestinal microsporidiosis.
abstract: Infection by the ingested pathogens of microsporidia occur primarily in immunosuppressed patients (including untreated HIV/AIDS) and are diagnosed by stool examination, small bowel biopsy with special stains, or electron microscopy (for definitive speciation), or by various molecular techniques. Although electron microscopy has been the definitive diagnostic tool for speciation, genetic sequencing increasingly provides the definitive diagnosis for new species, such as Anncaliia algerae. Further genetic sequencing of the common pathogens may allow for the development of advanced molecular diagnostics providing high diagnostic sensitivity and throughput.
authors.affiliation: Department of Anatomical Pathology, St Vincent's Hospital, Notre Dame University Medical School, Victoria Street, Darlinghurst 2010, Sydney, New South Wales, Australia.
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Field
authors.affiliation: Brigham and Women's Hospital/Harvard Medical School, 75 Francis Street, Amory 3, Boston, MA 02115, USA. Electronic address: dmilner@partners.org.
authors.forename: Danny A
authors.initials: DA
authors.lastname: Milner
mesh_terms: D003937:Diagnosis, Differential; D005243:Feces / Q000469:parasitology*; D006801:Humans; D016867:Immunocompromised Host; D016814:Microsporidia / Q000145:classification / Q000302:isolation & purification / Q000472:pathogenicity / Q000648:ultrastructure; D016881:Microsporidiosis / Q000175:diagnosis* / Q000469:parasitology
keywords: AIDS; Diarrhea; Enteritis; HIV; Immunosuppression; Microsporidium; Warthin-Starry