title: Performance of manual ventilation: how to define its efficiency in bench studies? A review of the literature.
abstract: Bench studies have become the preferred way to evaluate the performance of airway equipment, since clinical trials are not specifically required before marketing these devices. However, it is difficult to assess the efficiency of ventilation without recording physiological data. This review analyses how efficiency of manual ventilation has been defined in recent studies, and how their results may be affected. We searched electronic databases from 2000 to April 2014. The main inclusion criterion was the analysis of performance of ventilation. Nine relevant articles were selected from 53 eligible publications. Most studies used the same parameters; tidal volume and ventilation rate. However, there were significant differences between the definitions of performance of ventilation, both in terms of criteria of judgement and methods of analysis. None of these approaches is able to provide a clear understanding of variability of ventilation during a given period. A new definition may increase the relevance of bench studies to clinical medicine, by more appropriately assessing the performance of ventilation.
authors.affiliation: Department of Emergency Medicine & Critical Care, University of Franche Comté - Medical Centre, Besançon, France.
authors.forename: A
authors.initials: A
authors.lastname: Khoury
authors.affiliation: Clinical Investigation Centre Inserm CIC-1431, University of Franche Comté - Medical Centre, Besançon, France.
authors.forename: A
authors.initials: A
authors.lastname: De Luca
authors.affiliation: Clinical Investigation Centre Inserm CIC-1431, University of Franche Comté - Medical Centre, Besançon, France.
authors.forename: F S
authors.initials: FS
authors.lastname: Sall
authors.affiliation: Clinical Investigation Centre Inserm CIC-1431, University of Franche Comté - Medical Centre, Besançon, France.
authors.forename: L
authors.initials: L
authors.lastname: Pazart
authors.affiliation: Department of Emergency Medicine & Critical Care, University of Franche Comté - Medical Centre, Besançon, France.
authors.forename: G
authors.initials: G
authors.lastname: Capellier
mesh_terms: D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D006801:Humans; D008348:Manikins; D012121:Respiration, Artificial / Q000379:methods*; D016896:Treatment Outcome