title: Two new illudin type sesquiterpenoids from cultures of Phellinus tuberculosus and Laetiporus sulphureus.
abstract: Chemical investigation on the cultures of Phellinus tuberculosus and Laetiporus sulphureus lead to the isolation of two new illudin-type sesquiterpenoids (phellinuin J and sulphureuine A). Their structures were elucidated by 1D, 2D NMR and MS spectroscopic data. These compounds were purposely evaluated for their cytotoxicity against HL-60, SMMC-7721, A549, MCF-7, and SW480 cell lines.
authors.affiliation: a School of Medicine, Kunming University , Kunming 650214 , China.|b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
authors.forename: Jiang-Bo
authors.initials: JB
authors.lastname: He
authors.affiliation: a School of Medicine, Kunming University , Kunming 650214 , China.
authors.forename: Jian
authors.initials: J
authors.lastname: Tao
authors.affiliation: a School of Medicine, Kunming University , Kunming 650214 , China.
authors.forename: Xi-Song
authors.initials: XS
authors.lastname: Miao
authors.affiliation: a School of Medicine, Kunming University , Kunming 650214 , China.
authors.forename: Yun-Ping
authors.initials: YP
authors.lastname: Feng
authors.affiliation: c Department of Pharmacy , Xijing Hospital, Fourth Military Medical University , Xi'an 710032 , China.
authors.forename: Wei
authors.initials: W
authors.lastname: Bu
authors.affiliation: b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
authors.forename: Ze-Jun
authors.initials: ZJ
authors.lastname: Dong
authors.affiliation: b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
authors.forename: Zheng-Hui
authors.initials: ZH
authors.lastname: Li
authors.affiliation: b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
authors.forename: Tao
authors.initials: T
authors.lastname: Feng
authors.affiliation: b State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
authors.forename: Ji-Kai
authors.initials: JK
authors.lastname: Liu
mesh_terms: D000363:Agaricales / Q000737:chemistry*; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D055453:Coriolaceae; D004354:Drug Screening Assays, Antitumor; D018922:HL-60 Cells; D006801:Humans; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D012717:Sesquiterpenes; C000605301:phellinuin J; C000605302:sulphureuine A
keywords: Hymenochaetaceae; Laetiporus sulphureus; Phellinus tuberculosus; phellinuin J; sesquiterpenoids; sulphureuine A