title: Role of noroviruses as aetiological agents of diarrhoea in developing countries.
abstract: Diarrhoea is considered to be the second leading cause of death due to infections among children  < 5 years of age worldwide that may be caused by bacteria, parasites, viruses and non-infectious agents. The major causative agents of diarrhoea in developing countries may vary from those in developed countries. Noroviruses are considered to be the most common cause of acute diarrhoea in both children and adults in industrialized countries. On the other hand, there is a lack of comprehensive epidemiological evidence from developing countries that norovirus is a major cause of diarrhoea. In these regions, asymptomatic norovirus infections are very common, and similar detection rates have been observed in patients with diarrhoea and asymptomatic persons. This review summarizes the current knowledge of norovirus infection in developing countries and seeks to position infections with noroviruses among those of other enteropathogens in terms of disease burden in these regions.
authors.affiliation: Section for Clinical Research, Redeem Biomedical System, Buea, Cameroon.|Department of Infectious Diseases/Section of Clinical Virology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
authors.forename: James Ayukepi
authors.initials: JA
authors.lastname: Ayukekbong
authors.affiliation: Section for Clinical Research, Redeem Biomedical System, Buea, Cameroon.
authors.forename: Henry Nzike
authors.initials: HN
authors.lastname: Mesumbe
authors.affiliation: Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Nigeria.
authors.forename: Olufunmilayo G
authors.initials: OG
authors.lastname: Oyero
authors.affiliation: Department of Infectious Diseases/Section of Clinical Virology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Magnus
authors.initials: M
authors.lastname: Lindh
authors.affiliation: Department of Infectious Diseases/Section of Clinical Virology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Tomas
authors.initials: T
authors.lastname: Bergström
mesh_terms: D017250:Caliciviridae Infections / Q000453:epidemiology / Q000821:virology*; D003906:Developing Countries; D003967:Diarrhea / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D029322:Norovirus / Q000145:classification / Q000235:genetics / Q000502:physiology*; D010802:Phylogeny