title: Targeted resequencing analysis of 31 genes commonly mutated in myeloid disorders in serial samples from myelodysplastic syndrome patients showing disease progression.
authors.affiliation: LLR Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
authors.forename: A
authors.initials: A
authors.lastname: Pellagatti
authors.affiliation: LLR Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
authors.forename: S
authors.initials: S
authors.lastname: Roy
authors.affiliation: LLR Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
authors.forename: C
authors.initials: C
authors.lastname: Di Genua
authors.affiliation: NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
authors.forename: A
authors.initials: A
authors.lastname: Burns
authors.affiliation: H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
authors.forename: K
authors.initials: K
authors.lastname: McGraw
authors.affiliation: LLR Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
authors.forename: S
authors.initials: S
authors.lastname: Valletta
authors.affiliation: Department of Genetics, University of Navarra, Pamplona, Spain.
authors.forename: M J
authors.initials: MJ
authors.lastname: Larrayoz
authors.affiliation: LLR Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
authors.forename: M
authors.identifier: http://orcid.org/0000-0003-3458-9231
authors.initials: M
authors.lastname: Fernandez-Mercado
authors.affiliation: NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
authors.forename: J
authors.initials: J
authors.lastname: Mason
authors.affiliation: Department of Haematology, Royal Bournemouth Hospital, Bournemouth, UK.
authors.forename: S
authors.initials: S
authors.lastname: Killick
authors.affiliation: Hematology and Bone Marrow Transplantation Unit, University of Perugia, Perugia, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Mecucci
authors.affiliation: Department of Genetics, University of Navarra, Pamplona, Spain.
authors.forename: M J
authors.initials: MJ
authors.lastname: Calasanz
authors.affiliation: H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
authors.forename: A
authors.initials: A
authors.lastname: List
authors.affiliation: NIHR Biomedical Research Centre, University of Oxford, Oxford, UK.
authors.forename: A
authors.initials: A
authors.lastname: Schuh
authors.affiliation: LLR Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
authors.forename: J
authors.initials: J
authors.lastname: Boultwood
mesh_terms: D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics; D018450:Disease Progression; D020558:GTP Phosphohydrolases / Q000235:genetics; D016158:Genes, p53; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics; D009154:Mutation; D009190:Myelodysplastic Syndromes / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics; D012097:Repressor Proteins / Q000235:genetics; D012261:Ribonucleoproteins / Q000235:genetics
chemical_list: C473949:ASXL1 protein, human; D050676:Core Binding Factor Alpha 2 Subunit; D008565:Membrane Proteins; D009687:Nuclear Proteins; C493728:RUNX1 protein, human; D012097:Repressor Proteins; D012261:Ribonucleoproteins; C484334:ZRSR2 protein, human; D020558:GTP Phosphohydrolases; C579846:NRAS protein, human