title: Prevention of congenital Chagas through treatment of girls and women of childbearing age.
abstract: It is currently unknown whether treatment of Chagas disease decreases the risk of congenital transmission from previously treated mothers to their infants. In a cohort of women with Chagas disease previously treated with benznidazole, no congenital transmission of the disease was observed in their newborns. This finding provides support for the treatment of Chagas disease as early as possible.
authors.affiliation: Department of Parasitology and Chagas, Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Moscatelli
authors.affiliation: Department of Parasitology and Chagas, Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
authors.forename: Samanta
authors.initials: S
authors.lastname: Moroni
authors.affiliation: Department of Parasitology and Chagas, Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
authors.forename: Facundo
authors.initials: F
authors.lastname: García-Bournissen
authors.affiliation: Department of Parasitology and Chagas, Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
authors.forename: Griselda
authors.initials: G
authors.lastname: Ballering
authors.affiliation: Department of Parasitology and Chagas, Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
authors.forename: Margarita
authors.initials: M
authors.lastname: Bisio
authors.affiliation: Department of Parasitology and Chagas, Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
authors.forename: Héctor
authors.initials: H
authors.lastname: Freilij
authors.affiliation: Department of Parasitology and Chagas, Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina.
authors.forename: Jaime
authors.initials: J
authors.lastname: Altcheh
mesh_terms: D000293:Adolescent; D000328:Adult; D014355:Chagas Disease / Q000188:drug therapy / Q000469:parasitology / Q000635:transmission*; D002648:Child; D015331:Cohort Studies; D005260:Female; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D009593:Nitroimidazoles / Q000627:therapeutic use*; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000188:drug therapy; D011322:Primary Prevention; D014344:Trypanocidal Agents / Q000627:therapeutic use*; D014349:Trypanosoma cruzi; D055815:Young Adult
chemical_list: D009593:Nitroimidazoles; D014344:Trypanocidal Agents; C009999:benzonidazole