title: Copper-Mediated Aryloxylation and Vinyloxylation of β-C(sp(3))-H Bond of Propionamides with Organosilanes.
abstract: A novel copper-mediated method for the aryloxylation and vinyloxylation of β-C(sp(3))-H bonds of propioamides with organosilanes is described. The reaction proceeds with the assistance of an 8-aminoquinolyl auxiliary in a tandem way by the first oxidation of β-C(sp(3))-H bonds and subsequent arylation/vinylation to give the aryloxylation/vinyloxylation products. This unusual aryloxy/vinyloxy forming reaction offers a new avenue for the functionalization of unactivated sp(3) C-H bonds in organic synthesis.
authors.forename: Jitan
authors.initials: J
authors.lastname: Zhang
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.forename: Binjie
authors.initials: B
authors.lastname: Wang
authors.forename: Zhanxiang
authors.initials: Z
authors.lastname: Liu
authors.affiliation: ‡State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Zhang