title: The relationship between hepatitis B virus (HBV) load and levels of transforming growth factor beta 1 (TGF-β1) and soluble Fas (sFas) in human immunodeficiency virus patients with occult HBV infection.
abstract: The aim of this study was to evaluate the correlation between hepatitis B virus (HBV) load and serum levels of transforming growth factor beta 1 (TGF-β1) and soluble Fas (sFas) cytokines in human immunodeficiency virus (HIV) patients who have never been treated with antiretroviral therapy. HBV and hepatitis C virus (HCV) serological markers, sFas and TGF-β1 levels, and HBV load were evaluated in 116 patients. While there was no correlation between TGF-β1 levels and HBV load, a positive correlation between sFas levels and HBV load was observed in patients with occult HBV infection.
authors.affiliation: Virology Division, Keizo Asami Immunopathology Laboratory (LIKA), Federal University of Pernambuco (UFPE), Recife, Brazil.
authors.forename: Jéfferson Luis de Almeida
authors.initials: JL
authors.lastname: Silva
authors.forename: Dayse Maria Vasconcelos
authors.initials: DM
authors.lastname: De Deus
authors.forename: Regina Célia
authors.initials: RC
authors.lastname: Moreira
authors.forename: Clarice Neuenschwander Lins
authors.initials: CN
authors.lastname: de Morais
authors.forename: Maria Rosângela Cunha Duarte
authors.initials: MR
authors.lastname: Coêlho
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D060085:Coinfection / Q000097:blood* / Q000821:virology; D053222:Fas Ligand Protein / Q000097:blood*; D005260:Female; D015658:HIV Infections / Q000097:blood* / Q000821:virology; D015497:HIV-1 / Q000502:physiology; D006509:Hepatitis B / Q000097:blood* / Q000821:virology; D006515:Hepatitis B virus / Q000235:genetics / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D053773:Transforming Growth Factor beta1 / Q000097:blood*; D019562:Viral Load; D055815:Young Adult
chemical_list: D053222:Fas Ligand Protein; D053773:Transforming Growth Factor beta1