title: Small bowel diverticulitis with severe anemia and abdominal pain.
abstract: The current case report is related to a male patient with diabetes, obesity [body mass index (BMI) 33], hypertension and recurrence of anemia associated to melena and deep asthenia. M.P., a 60-year-old obese individual, was referred to our department by the primary care unit (PCU) of our hospital for severe anemia (Hemoglobin 6.5 g/dL) associated to episodes of melena and abdominal pain. In the past 5 mo the patient referred to the local hospital 3 times for episodes of melena (hemoglobin levels showed anemia 9.8 g/dL) but the main gastroenterological exams were completely negative (colonoscopy and gastroscopy). The PCU of our Hospital, after stabilization of the main parameters and blood transfusion for the low levels of hemoglobin, referred the patient to gastroenterologists: the patient was subjected to both colonoscopy and gastroscopy that were negative. Due to the condition of acute severe hemorrhage the patient, during the first 3 h from the access to the PCU, was subjected to arteriography that did not reveal any hemorrhagic foci or vascular alterations. The video capsule for the study of the small bowel showed the presence of blood beginning from the third portion of duodenum but deep gastroscopy did not reveal it. The patient was then subjected to double balloon endoscopy that revealed a severe diverticulosis of the small bowel with blood from the diverticula. The entero-tomografia computerizzata confirmed the diagnosis and revealed an extension of the diverticula for almost the entire small bowel (no diverticula in the colon). The patient was subjected to wide spectrum antibiotic therapy with resolution of the symptoms and stabilization of hemoglobin levels. The surgeon suggests no indication to surgery for the wide area involved from the disease and potential high risk of complication due to the high BMI. At home, the patient started a monthly therapy with rifaximin and probiotics associated to mesalazine. At present, after 12 mo from the last episode of hemorrhage, the patient is in good clinical condition, reduced his body weight of about 7 kg and the hemoglobin levels appear in slow progressive increase (last measurement 13.2 g/dL).
authors.affiliation: Samuele De Minicis, Filippo Antonini, Valerio Belfiori, Massimiliano Lo Cascio, Barbara Marraccini, Simona Piergallini, Giampiero Macarri, Department of Gastroenterology, Augusto Murri Hospital, Polytechnic University of Marche, 63900 Fermo, Italy.
authors.forename: Samuele
authors.initials: S
authors.lastname: De Minicis
authors.affiliation: Samuele De Minicis, Filippo Antonini, Valerio Belfiori, Massimiliano Lo Cascio, Barbara Marraccini, Simona Piergallini, Giampiero Macarri, Department of Gastroenterology, Augusto Murri Hospital, Polytechnic University of Marche, 63900 Fermo, Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Antonini
authors.affiliation: Samuele De Minicis, Filippo Antonini, Valerio Belfiori, Massimiliano Lo Cascio, Barbara Marraccini, Simona Piergallini, Giampiero Macarri, Department of Gastroenterology, Augusto Murri Hospital, Polytechnic University of Marche, 63900 Fermo, Italy.
authors.forename: Valerio
authors.initials: V
authors.lastname: Belfiori
authors.affiliation: Samuele De Minicis, Filippo Antonini, Valerio Belfiori, Massimiliano Lo Cascio, Barbara Marraccini, Simona Piergallini, Giampiero Macarri, Department of Gastroenterology, Augusto Murri Hospital, Polytechnic University of Marche, 63900 Fermo, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Lo Cascio
authors.affiliation: Samuele De Minicis, Filippo Antonini, Valerio Belfiori, Massimiliano Lo Cascio, Barbara Marraccini, Simona Piergallini, Giampiero Macarri, Department of Gastroenterology, Augusto Murri Hospital, Polytechnic University of Marche, 63900 Fermo, Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Marraccini
authors.affiliation: Samuele De Minicis, Filippo Antonini, Valerio Belfiori, Massimiliano Lo Cascio, Barbara Marraccini, Simona Piergallini, Giampiero Macarri, Department of Gastroenterology, Augusto Murri Hospital, Polytechnic University of Marche, 63900 Fermo, Italy.
authors.forename: Simona
authors.initials: S
authors.lastname: Piergallini
authors.affiliation: Samuele De Minicis, Filippo Antonini, Valerio Belfiori, Massimiliano Lo Cascio, Barbara Marraccini, Simona Piergallini, Giampiero Macarri, Department of Gastroenterology, Augusto Murri Hospital, Polytechnic University of Marche, 63900 Fermo, Italy.
authors.forename: Piergiorgio
authors.initials: P
authors.lastname: Mosca
authors.affiliation: Samuele De Minicis, Filippo Antonini, Valerio Belfiori, Massimiliano Lo Cascio, Barbara Marraccini, Simona Piergallini, Giampiero Macarri, Department of Gastroenterology, Augusto Murri Hospital, Polytechnic University of Marche, 63900 Fermo, Italy.
authors.forename: Giampiero
authors.initials: G
authors.lastname: Macarri
keywords: Abdominal pain; Anemia; Diverticulitis; Intestinal bleeding; Small bowel