title: Studying the interaction of stent-grafts and treated abdominal aortic aneurysms: time to move caudally!
abstract: Since the advent of endovascular repair of aortic aneurysms (EVAR), clinical focus has been on preventing loss of sealing at the level of the infrarenal neck, which leads to type I endoleak and repressurization of the aneurysm sac. Enhanced mechanisms for central fixation and seal have consequently lowered the incidence of migration and endoleaks. However, endograft limb thrombosis and its causal mechanisms have not been addressed adequately in the literature. This article reviews the pathophysiological mechanisms associated with limb thrombosis in order to facilitate better clinical judgment to prevent iliac adverse effects.
authors.affiliation: Department of Vascular Surgery, "Democritus" University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece efstratiosgeorg@gmail.com.
authors.forename: Efstratios
authors.initials: E
authors.lastname: Georgakarakos
authors.affiliation: Department of Surgery, Vascular Surgery Unit, Medical School, University of Ioannina, Ioannina, Greece.
authors.forename: Anastasios
authors.initials: A
authors.lastname: Raptis
authors.affiliation: Department of Vascular Surgery, "Democritus" University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Schoretsanitis
authors.affiliation: Department of Vascular Surgery, St. Franziskus Hospital and University Clinic Münster, Münster, Germany.
authors.forename: Theodosios
authors.initials: T
authors.lastname: Bisdas
authors.affiliation: Department of Vascular Surgery, "Democritus" University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece Department of Vascular Surgery, St. Franziskus Hospital and University Clinic Münster, Münster, Germany.
authors.forename: Efthymios
authors.initials: E
authors.lastname: Beropoulis
authors.affiliation: Department of Vascular Surgery, "Democritus" University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
authors.forename: George S
authors.initials: GS
authors.lastname: Georgiadis
authors.affiliation: Department of Surgery, Vascular Surgery Unit, Medical School, University of Ioannina, Ioannina, Greece.
authors.forename: Miltiadis
authors.initials: M
authors.lastname: Matsagkas
authors.affiliation: Department of Mathematics, University of Ioannina, Ioannina, Greece.
authors.forename: Michalis
authors.initials: M
authors.lastname: Xenos
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D001027:Aortography / Q000379:methods; D001696:Biomechanical Phenomena; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation*; D057867:Endoleak / Q000209:etiology / Q000503:physiopathology; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation*; D006083:Graft Occlusion, Vascular / Q000209:etiology / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D007083:Iliac Artery / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D011474:Prosthesis Design; D015607:Stents; D013927:Thrombosis / Q000209:etiology / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: abdominal aortic aneurysm; endovascular aneurysm repair; graft limb; hemodynamics; iliac artery; iliac artery occlusion; stent-graft; thrombosis; tortuosity