title: Microalbuminuria and prediction of cardiovascular complications in patients with coronary artery disease and type 2 diabetes mellitus after CABG surgery.
abstract: BACKGROUND
  This investigation was aimed at assessing the clinical significance of microalbuminuria (MA) in predicting in-hospital adverse outcomes amongst the patients with coronary artery disease (CAD) and type 2 diabetes mellitus (DM) who have undergone coronary artery bypass graft (CABG) surgery.
  
  
  METHODS
  We recruited 720 consecutive Caucasian (Russian) patients who underwent CABG surgery during 2011-2012.
  
  
  RESULTS
  Patients with renal dysfunction (RD) and without type 2 DM had significantly higher median serum creatinine seven days after CABG surgery compared to patients without RD and type 2 DM. There were no statistically significant intergroup differences regarding glomerular filtration rate. However, the highest median of urine albumin excretion 24hours before and seven days after CABG surgery was detected in patients with RD and type 2 DM whilst the lowest median was noted in patients without RD and type 2 DM. Median of urine albumin excretion 24hours before and seven days after CABG surgery in patients with adverse outcome was significantly higher compared to patients with a favourable outcome.
  
  
  CONCLUSIONS
  We suggest that the determination of MA before and after CABG surgery may assist in predicting adverse outcomes after CABG surgery.
authors.affiliation: Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation.
authors.forename: Kristina S
authors.initials: KS
authors.lastname: Shafranskaya
authors.affiliation: Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation.
authors.forename: Vasiliy V
authors.initials: VV
authors.lastname: Kashtalap
authors.affiliation: Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation.
authors.forename: Anton G
authors.initials: AG
authors.lastname: Kutikhin
authors.affiliation: Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation. Electronic address: barbol@cardio.kem.ru.
authors.forename: Olga L
authors.initials: OL
authors.lastname: Barbarash
authors.affiliation: Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation.
authors.forename: Leonid S
authors.initials: LS
authors.lastname: Barbarash
mesh_terms: D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000453:epidemiology / Q000652:urine*; D015897:Comorbidity; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000401:mortality; D003324:Coronary Artery Disease / Q000453:epidemiology* / Q000601:surgery*; D003404:Creatinine / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000453:epidemiology*; D005260:Female; D005919:Glomerular Filtration Rate; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D051437:Renal Insufficiency / Q000097:blood / Q000453:epidemiology*; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology
chemical_list: D003404:Creatinine
keywords: Adverse outcomes; Complications; Coronary artery bypass graft surgery; Coronary artery disease; EuroSCORE; Microalbuminuria