title: Membranous nephropathy associated with gastrointestinal stromal tumour: a case report.
abstract: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in older adults. The association of MN with neoplasia has been controversial, but several recent studies have shown increase incidence of cancer in patients with MN [1]. We report a case of a 49-year-old male with severe nephrotic syndrome and concomitant jejunal gastrointestinal stromal tumour (GIST). The combination of preoperative Imatinib mesylate chemotherapy and tumour excision was followed by complete resolution of proteinuria within 19 months, without specific treatment for MN. An association between MN and GIST has never previously been reported in the literature.
authors.affiliation: Department of Pathology , Emory University Hospital.
authors.forename: Adela
authors.initials: A
authors.lastname: Cimic
authors.affiliation: Department of Medicine, Renal Division , Emory University School of Medicine , Atlanta, GA , USA.
authors.forename: Stephen O
authors.initials: SO
authors.lastname: Pastan
authors.affiliation: Department of Pathology , Emory University Hospital.
authors.forename: Vanesa
authors.initials: V
authors.lastname: Bijol
keywords: GIST; membranous nephropathy; proteinuria