title: Effect of lit-moxa stimulation of Guanyuan (CV 4) acupoint on levels of lactic acid and superoxide dismutase in skeletal muscle of rats.
abstract: OBJECTIVE
  To observe the effect of lit-moxa stimu- lating acupoint Guanyuan (CV 4) on lactic acid and super-oxide dismutase (SOD) in skeletal muscle after exercise exhaustion.
  
  
  METHODS
  Twenty-eight adult male Sprague-Dawley rats were randomly divided into normal control group, exhausted control group, exercise group and moxibustion group using exercise training and mild heating with lit-moxa stick as treatment methods. The exhausted control group, moxibustion group and exercise group received an exhaustive swimming after 20 days of intervention. Swimming exhausted times were recorded. Lactic acid and SOD concentration in soleus muscle were detected and compared between every two groups.
  
  
  RESULTS
  The swimming exhausted times of the moxibustion group and the exercise group were significantly increased compare to the exhausted control group (P < 0.05). The lactic acid of the exhausted control group was significantly increased comparing with the normal control group (P < 0.05), and the lactic acid of the moxibustion group and the exercise group were significantly lower than that of the exhausted control group (P < 0.05). The SOD level of the exhausted control group was significantly decreased comparing with the normal control group (P < 0.05), and the SOD level of the moxibustion group and the exercise group were significantly higher than that of the exhausted control group (both, P < 0.05). There was no statistical difference between the moxibustion group and the exercise group.
  
  
  CONCLUSIONS
  With lit moxa stick, heat stimulating acupoint of Guanyuan (CV 4) decreased the levels of lactic acid and SOD in rat's skeletal muscle.
authors.forename: Mo
authors.initials: M
authors.lastname: Jie
authors.forename: Wu
authors.initials: W
authors.lastname: Lili
authors.forename: Sun
authors.initials: S
authors.lastname: Zhifang
authors.forename: Wang
authors.initials: W
authors.lastname: Hongbin
authors.forename: Ding
authors.initials: D
authors.lastname: Na
authors.forename: He
authors.initials: H
authors.lastname: Long
authors.forename: Zhang
authors.initials: Z
authors.lastname: Lufen
authors.forename: Liu
authors.initials: L
authors.lastname: Tonghua
authors.forename: Li
authors.initials: L
authors.lastname: Xiaohong
mesh_terms: D015669:Acupuncture Points; D000818:Animals; D017079:Exercise Tolerance; D006801:Humans; D019344:Lactic Acid / Q000378:metabolism*; D008297:Male; D009071:Moxibustion; D018482:Muscle, Skeletal / Q000201:enzymology / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013482:Superoxide Dismutase / Q000378:metabolism*
chemical_list: D019344:Lactic Acid; D013482:Superoxide Dismutase