title: A dive into membrane dynamics with sponge peptides.
abstract: In this issue of Chemistry & Biology, Arita et al. (2015) report that theonellamides can specifically recognize cholesterol in liquid-disordered environment, modulate membrane order, and change cell morphology and thus may serve as probes to unveil the enigmatic nature of cell membranes.
authors.affiliation: Department of Medicinal Chemistry, University of Florida, Gainesville, FL 32610, USA; Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL 32610, USA.
authors.forename: Danmeng
authors.initials: D
authors.lastname: Luo
authors.affiliation: Department of Medicinal Chemistry, University of Florida, Gainesville, FL 32610, USA; Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL 32610, USA. Electronic address: luesch@cop.ufl.edu.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Luesch
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000378:metabolism*; D002784:Cholesterol / Q000737:chemistry*; D006801:Humans; D010456:Peptides, Cyclic / Q000737:chemistry*
chemical_list: D010456:Peptides, Cyclic; D002784:Cholesterol