title: Breast cancer in male-to-female (MtF) transgender patients: is hormone receptor negativity a feature?
abstract: A 41-year-old male-to-female (MtF) transgender patient presented with a symptomatic tender lump in the left breast. There was no family history of breast cancer. She had been receiving estrogen therapy for 14 years to maintain her secondary sexual characteristics. Triple assessment revealed a 13 mm triple-negative grade 3 invasive ductal carcinoma. The tumour was completely excised following a left wide local excision and sentinel lymph node biopsy. There was no regional lymph node involvement. She was referred to the oncologist for adjuvant chemotherapy and radiotherapy.
authors.affiliation: Breast Surgery Unit, Wrexham Maelor Hospital, Wrexham, UK.
authors.forename: Zhi Hao
authors.identifier: http://orcid.org/0000-0002-5801-5884
authors.initials: ZH
authors.lastname: Teoh
authors.affiliation: Wrexham Maelor Hospital, Wrexham, UK.
authors.forename: David
authors.initials: D
authors.lastname: Archampong
authors.affiliation: Wrexham Maelor Hospital, Wrexham, UK.
authors.forename: Tim
authors.initials: T
authors.lastname: Gate
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis* / Q000601:surgery; D004967:Estrogens / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D011960:Receptors, Estrogen / Q000032:analysis*; D021701:Sentinel Lymph Node Biopsy; D063106:Transgender Persons
chemical_list: D004967:Estrogens; D011960:Receptors, Estrogen