title: [Clinical and laboratory diagnosis of an acute biliary pancreatitis].
abstract: In 126 patients, suffering an acute biliary pancreatitis (ABP), clinical examination was conducted. In 65 patients (1-st group) the isolated cholecystolithiasis was noted; in 35 (2-nd group)--cholelithiasis, which did not cause obturation of common biliary duct; in 26 (3-rd group)--cholelithiasis, which caused the biliary ways obturation (including calculi, which were incorporated into the duodenal papilla magna ostium). Clinical course of an ABP have differed depending on localization of calculi of extrahepatic biliary ducts. In patients, suffering ABP, a biochemical signs of hepatocytes functional disorders were observed, impacting the need for hepatoprotector preparations inclusion into complex of perioperative conservative therapy. Determination of activity of pancreatic α-amylase in the blood serum and conduction of the ACTIM Pancreatitis test con- stitute the most sensitive and specific methods of the ABP biochemical diagnosis.
authors.forename: S M
authors.initials: SM
authors.lastname: Vasylyuk
authors.forename: V V
authors.initials: VV
authors.lastname: Ivanyna
mesh_terms: D000208:Acute Disease; D000328:Adult; D000410:Alanine Transaminase / Q000378:metabolism; D001219:Aspartate Aminotransferases / Q000378:metabolism; D017734:Bile Ducts, Extrahepatic / Q000201:enzymology / Q000473:pathology; D041761:Cholecystolithiasis / Q000175:diagnosis* / Q000201:enzymology / Q000473:pathology; D005260:Female; D005704:Gallbladder / Q000378:metabolism / Q000473:pathology; D005982:Glutathione Transferase / Q000378:metabolism; D022781:Hepatocytes / Q000201:enzymology / Q000473:pathology; D006801:Humans; D008099:Liver / Q000201:enzymology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000201:enzymology / Q000473:pathology; D055292:Pancreatic alpha-Amylases / Q000097:blood; D010195:Pancreatitis / Q000175:diagnosis* / Q000201:enzymology / Q000473:pathology; D014357:Trypsin / Q000652:urine; D014362:Trypsinogen / Q000652:urine
chemical_list: C064831:PRSS2 protein, human; D014362:Trypsinogen; D005982:Glutathione Transferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D055292:Pancreatic alpha-Amylases; D014357:Trypsin