title: Young-onset dementia epidemiology applied to neuropsychiatry practice.
abstract: A substantial number of adults suffer young-onset dementia (YOD). The diversity of types and syndromes makes recognition and diagnosis difficult. An algorithmic approach to interpreting clinical data, informed by clinical epidemiology, integrates data pertaining to defining syndromes and their chronology and tempo, family history, and other neuropsychiatric features and neurologic signs, is used to reach a preliminary diagnosis and direct diagnostic tests and their interpretation. Screening for YOD in the psychiatric context is a rational process in which vigilance is combined with careful searches for red flags that signal a neurodegenerative etiology.
authors.affiliation: Geriatric Psychiatry Division, Department of Psychiatry, Zucker Hillside Hospital, 75-59 263rd Street, Glen Oaks, NY 11004, USA.
authors.forename: Bhargavi
authors.initials: B
authors.lastname: Devineni
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 279, Baltimore, MD 21287, USA. Electronic address: conyike1@jhmi.edu.
authors.forename: Chiadi U
authors.initials: CU
authors.lastname: Onyike
mesh_terms: D017668:Age of Onset; D003704:Dementia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000523:psychology; D003937:Diagnosis, Differential; D003951:Diagnostic Errors / Q000517:prevention & control; D018450:Disease Progression; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D019636:Neurodegenerative Diseases / Q000150:complications*; D012307:Risk Factors
keywords: Differential diagnosis; Epidemiology; Risk factors; Screening; Young-onset dementia