title: Prevalence of microorganisms and immunoglobulins in children with tonsillar hypertrophy and adenoiditis.
abstract: BACKGROUND
  Benign idiopathic tonsillar hypertrophy (HBI) may affect a child's quality of life and sleep. Several studies have sought to relate the clinical features of HBI with the infectious and/or immunologic changes that occur.
  
  
  OBJECTIVE
  To increase the knowledge of the etiology of HBI.
  
  
  RESULTS
  From 2012 to 2013 we conducted a retrospective observational study of 101 children with HBI who underwent tonsillectomies at Ambulatory ENT General Hospital of the East Zone of São Paulo City, a region with a poor socioeconomic population. Preoperative serologic results were available to confirm mononucleosis, cytomegalovirus, anti-streptolysin O (ASLO) and immunoglobulins. The mean patient age was 5.8 years (55% male, 45% female). Using the Mann-Whitney U test, we identified significant gender differences in the parameters of immunoglobulins (Ig) M (IgM), IgA, and IgE. Forty-seven percent of the patients had increased ASLO levels, and 37% had increased IgE levels.
  
  
  CONCLUSIONS
  An evaluation of a patient's serologic parameters and laboratory results may be relevant to the etiology and prevention of HBI. Based on the results obtained from the study sample, the identification of etiologic agents and causative factors remain a public health challenge that affects the quality of life of children.
authors.affiliation: MD; Extension Course Student, Universidade Anhembi Morumbi - UAM, São Paulo, SP, Brazil.
authors.forename: Henrique Prestes
authors.initials: HP
authors.lastname: Miramontes
authors.affiliation: PhD; Universidade Federal de São Paulo - UNIFESP, São Paulo, SP, Brazil.
authors.forename: Djalma José
authors.initials: DJ
authors.lastname: Fagundes
authors.affiliation: MS, Universidade Anhembi Morumbi - UAM, São Paulo, SP, Brazil.
authors.forename: Julia Coelho Lima E
authors.initials: JC
authors.lastname: Jurgielewicz
authors.affiliation: MS, Universdidade Cidade de São Paulo - UNICID, São Paulo, SP, Brazil.
authors.forename: Haroldo Prestes
authors.initials: HP
authors.lastname: Miramontes Neto
authors.affiliation: MS, Universidade Anhembi Morumbi - UAM, São Paulo, SP, Brazil.
authors.forename: Renan Gianotto de
authors.initials: RG
authors.lastname: Oliveira
authors.affiliation: MS, Universidade Anhembi Morumbi - UAM, São Paulo, SP, Brazil.
authors.forename: Gustavo Gianotto de
authors.initials: GG
authors.lastname: Oliveira
authors.affiliation: PhD; Hospital Central de Guaianases, São Paulo, SP, Brazil; Universidade Anhembi Morumbi - UAM, São Paulo, SP, Brazil.
authors.forename: Maria Rosa Machado de
authors.initials: MR
authors.lastname: Souza
keywords: child; immune system; immunoglobulins; tonsillectomy