title: A first case report of diffuse acneiform eruption caused by capecitabine in a patient with small-cell neuroendocrine lung carcinoma.
abstract: Capecitabine is a chemotherapeutic agent which is converted to fluorouracil by thymidine phosphorylase in human body. It is one of the commonly used agents in colorectal and metastatic breast cancers. Hand-foot syndrome is most commonly observed adverse effect of capecitabine; however, it has several adverse cutaneous and mucosal effects. To the best of our knowledge, no case with acneiform eruption has been reported so far. Here, we presented a 54-year-old man with development of capecitabine-related acneiform drug eruption.
authors.affiliation: Department of Dermatology, Mugla Sitki Kocman University Training and Research Hospital, Mugla, Turkey.
authors.forename: Asude
authors.initials: A
authors.lastname: Kara
authors.affiliation: Department of Dermatology, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
authors.forename: EmineTugba
authors.initials: E
authors.lastname: Alatas
authors.affiliation: Department of Dermatology, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
authors.forename: Gursoy
authors.initials: G
authors.lastname: Dogan
authors.affiliation: Department of Pathology, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey.
authors.forename: Serkan Y
authors.initials: SY
authors.lastname: Celik
authors.affiliation: Department of Medical Oncology, Faculty of Medicine, Mugla Sitki Kocman University, Mugla, Turkey mugla.medicaloncology@gmail.com.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Tanriverdi
mesh_terms: D017486:Acneiform Eruptions / Q000139:chemically induced*; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000069287:Capecitabine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D055752:Small Cell Lung Carcinoma / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D000069287:Capecitabine
keywords: Capecitabine; acneiform drug eruption; chemotherapeutic agent