title: Emotional memory.
abstract: Research on the reconsolidation effect was greatly revitalized by the highly analytic demonstration of memory reconsolidation (Nader et al. Nature 406:722-726, 2000) in a well-defined behavioral protocol (auditory fear conditioning in the rat). Since this study, reconsolidation has been demonstrated in hundreds of studies over a range of species, tasks, and amnesic agents. Evidence for reconsolidation does not come solely from the behavioral level of analysis. Cellular and molecular correlates of reconsolidation have also been found. In this chapter, I will first define the evidence on which reconsolidation is concluded to exist. I will then discuss some of the conceptual issues facing the field in determining when reconsolidation does and does not occur. Lastly I will explain the clinical implications of this effect.
authors.affiliation: Psychology Department, McGill University, 1205 Dr. Penfield Ave, Montreal, QC, Canada, H3A 1B1, karim.nader@mcgill.ca.
authors.forename: Karim
authors.initials: K
authors.lastname: Nader
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D001921:Brain / Q000187:drug effects / Q000503:physiopathology*; D003071:Cognition / Q000187:drug effects; D003072:Cognition Disorders / Q000503:physiopathology / Q000523:psychology* / Q000628:therapy; D015928:Cognitive Behavioral Therapy / Q000379:methods; D004644:Emotions / Q000187:drug effects; D006801:Humans; D008568:Memory / Q000187:drug effects; D008569:Memory Disorders / Q000503:physiopathology / Q000523:psychology* / Q000628:therapy; D018697:Nootropic Agents / Q000627:therapeutic use
chemical_list: D018697:Nootropic Agents