title: A case of adult atypical haemolytic uraemic syndrome related to anti-factor H autoantibodies successfully treated by plasma exchange, corticosteroids and rituximab.
abstract: Complement factor H auto-antibodies (CFH-ab) are a rare cause (6-10%) of atypical haemolytic uraemic syndrome (aHUS). All observations previously described were retrospective and occurred in children or teenagers. We report the first case of aHUS associated with anti-CFH antibodies in an adult patient who was successfully treated by plasma exchange, corticosteroids and rituximab.
authors.affiliation: Department of Néphrology , Hospital Calmette , CHRU-Lille, Lille.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Lionet
authors.affiliation: Department of Néphrology , Hospital Calmette , CHRU-Lille, Lille.
authors.forename: François
authors.initials: F
authors.lastname: Provôt
authors.affiliation: Department of Néphrology , Hospital Calmette , CHRU-Lille, Lille.
authors.forename: François
authors.initials: F
authors.lastname: Glowacki
authors.affiliation: Department of Immunology , Höpital Europeen Georges Pompidou, Paris , France.
authors.forename: Veronique
authors.initials: V
authors.lastname: Frémeaux-Bacchi
authors.affiliation: Department of Néphrology , Hospital Calmette , CHRU-Lille, Lille.
authors.forename: Marc
authors.initials: M
authors.lastname: Hazzan
keywords: anti-CFH autoantibodies; atypical HUS; plasma exchange; rituximab