title: What is the mechanism of action of praziquantel and how might resistance strike?
authors.affiliation: Skaggs School of Pharmacy & Pharmaceutical Sciences, UC San Diego, La Jolla, CA 92093, USA.
authors.forename: Pauline M
authors.initials: PM
authors.lastname: Cupit
authors.forename: Charles
authors.initials: C
authors.lastname: Cunningham
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology* / Q000627:therapeutic use; D004351:Drug Resistance; D006801:Humans; D011223:Praziquantel / Q000494:pharmacology* / Q000627:therapeutic use; D012547:Schistosoma / Q000187:drug effects* / Q000502:physiology; D012552:Schistosomiasis / Q000188:drug therapy* / Q000469:parasitology
chemical_list: D000871:Anthelmintics; D011223:Praziquantel
keywords: drug resistance; mechanism of action; praziquantel; schistosomes; schistosomiasis