title: Neuron migration: anillin protects leading edge actin.
abstract: Establishment of a neuronal system requires proper regulation of the F-actin-rich leading edges of migrating neurons and neurite growth cones. A new study shows that RhoG signals through the multi-domain protein anillin to stabilize F-actin in these structures.
authors.affiliation: (1)Curriculum in Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
authors.forename: Kathryn
authors.initials: K
authors.lastname: Rehain
authors.affiliation: (1)Curriculum in Genetics, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Biology, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address: asm@unc.edu.
authors.forename: Amy Shaub
authors.initials: AS
authors.lastname: Maddox
mesh_terms: D008841:Actin Cytoskeleton / Q000378:metabolism*; D000818:Animals; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D008840:Microfilament Proteins / Q000378:metabolism*; D016501:Neurites / Q000502:physiology*; D020744:rac GTP-Binding Proteins / Q000378:metabolism*
chemical_list: D029742:Caenorhabditis elegans Proteins; D008840:Microfilament Proteins; D020744:rac GTP-Binding Proteins