title: Radical Instability in Aid of Efficiency: A Powerful Route to Highly Functional MIDA Boronates.
abstract: The inability of the sp(3) boron in MIDA boronates to stabilize an adjacent radical makes possible the efficient addition of a wide array of xanthates to vinyl MIDA boronate, leading to highly functionalized and diverse aliphatic organoboron structures. The lack of radical stabilization also allows the exchange of the xanthate in the adducts with a bromine. In one case, the bromine was substituted to generate a cyclopropyl MIDA derivative.
authors.affiliation: Laboratoire de Synthèse Organique, CNRS UMR 7652, Ecole Polytechnique, 91128 Palaiseau Cedex, France.
authors.forename: Béatrice
authors.initials: B
authors.lastname: Quiclet-Sire
authors.affiliation: Laboratoire de Synthèse Organique, CNRS UMR 7652, Ecole Polytechnique, 91128 Palaiseau Cedex, France.
authors.forename: Samir Z
authors.initials: SZ
authors.lastname: Zard
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D003521:Cyclopropanes / Q000737:chemistry*; D005609:Free Radicals / Q000737:chemistry; D005998:Glycine / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D001897:Boronic Acids; D003521:Cyclopropanes; D005609:Free Radicals; C586344:trans-2-(trifluoromethyl)cyclopropylboronic acid N-methyliminodiacetic acid; D005998:Glycine