title: Eccrine Porocarcinoma Treated by Mohs Micrographic Surgery: Over 6-Year Follow-up of 12 Cases and Literature Review.
abstract: BACKGROUND
  Eccrine porocarcinoma (EPC) has a poor prognosis after standard wide local excision (WLE), with 20% local recurrence, 20% regional and 12% distant metastatic rates. Mohs micrographic surgery (MMS) has been used as a promising treatment.
  
  
  OBJECTIVE
  To review the use of MMS for EPC and assess treatment outcomes.
  
  
  METHODS
  This was a retrospective case series of 12 EPC patients treated by MMS between 1984 and 2013 in the institution. Furthermore, a literature review revealed an additional 17 cases of EPC managed by MMS.
  
  
  RESULTS
  Of 29 cases of EPC treated by MMS, outcome was established in 27 cases. The patients had a significantly longer mean follow-up period of 6 years (range, 4-206 months), as compared with 19 months (range, 2-48 months) in reported cases. Two patients had regional lymph node metastasis after MMS. The regional metastatic rates to lymph nodes were 7% (2/27). There was no local recurrence, distant metastasis, or disease-specific death in the 27 cases studied.
  
  
  CONCLUSIONS
  To the best of the authors' knowledge, this is the single largest case series of EPCs treated by MMS and the authors' data demonstrated that MMS may be superior to the standard WLE.
authors.affiliation: *Department of Dermatology, University of Wisconsin, Madison, Wisconsin; †Department of Dermatology, Northwest Permanente, Portland, Oregon.
authors.forename: Yaohui G
authors.initials: YG
authors.lastname: Xu
authors.forename: Juliet
authors.initials: J
authors.lastname: Aylward
authors.forename: B Jack
authors.initials: BJ
authors.lastname: Longley
authors.forename: Molly A
authors.initials: MA
authors.lastname: Hinshaw
authors.forename: Stephen N
authors.initials: SN
authors.lastname: Snow
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D057090:Eccrine Porocarcinoma / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D015580:Mohs Surgery; D012189:Retrospective Studies; D013544:Sweat Gland Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome