title: Anniston community health survey: Follow-up and dioxin analyses (ACHS-II)--methods.
abstract: High serum concentrations of polychlorinated biphenyls (PCBs) have been reported previously among residents of Anniston, Alabama, where a PCB production facility was located in the past. As the second of two cross-sectional studies of these Anniston residents, the Anniston Community Health Survey: Follow-Up and Dioxin Analyses (ACHS-II) will yield repeated measurements to be used to evaluate changes over time in ortho-PCB concentrations and selected health indicators in study participants. Dioxins, non-ortho PCBs, other chemicals, heavy metals, and a variety of additional clinical tests not previously measured in the original ACHS cohort will be examined in ACHS-II. The follow-up study also incorporates a questionnaire with extended sections on diet and occupational history for a more comprehensive assessment of possible exposure sources. Data collection for ACHS-II from 359 eligible participants took place in 2014, 7 to 9 years after ACHS.
authors.affiliation: National Cancer Institute, National Institutes of Health, Research Triangle, NC, USA. birnbaumls@niehs.nih.gov.
authors.forename: Linda S
authors.initials: LS
authors.lastname: Birnbaum
authors.affiliation: Oak Ridge Institute for Science and Education (ORISE) Research Participation Program, Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA.
authors.forename: N D
authors.initials: ND
authors.lastname: Dutton
authors.affiliation: Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA.
authors.forename: C
authors.initials: C
authors.lastname: Cusack
authors.affiliation: University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: S T
authors.initials: ST
authors.lastname: Mennemeyer
authors.affiliation: Agency for Toxic Substances and Disease Registry, Atlanta, GA, USA.
authors.forename: M
authors.initials: M
authors.lastname: Pavuk
mesh_terms: D000407:Alabama; D003430:Cross-Sectional Studies; D004032:Diet; D004041:Dietary Fats; D004785:Environmental Pollutants / Q000737:chemistry*; D005227:Fatty Acids; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D008297:Male; D010938:Plant Oils / Q000494:pharmacology; D011078:Polychlorinated Biphenyls / Q000737:chemistry* / Q000493:pharmacokinetics; D000072317:Polychlorinated Dibenzodioxins / Q000737:chemistry* / Q000493:pharmacokinetics; D013395:Sucrose / Q000031:analogs & derivatives; D055815:Young Adult
chemical_list: D004041:Dietary Fats; D004785:Environmental Pollutants; D005227:Fatty Acids; D010938:Plant Oils; D000072317:Polychlorinated Dibenzodioxins; D013395:Sucrose; C013692:sucrose polyester; D011078:Polychlorinated Biphenyls
keywords: Anniston; Dioxins; Heavy metals; PBDEs; PCBs; PCDDs; PCDFs; Polychlorinated biphenyls