title: Plasma-based ambient ionization mass spectrometry in bioanalytical sciences.
abstract: Plasma-based ambient ionization mass spectrometry techniques are gaining growing interest due to their specific features, such as the need for little or no sample preparation, its high analysis speed, and the ambient experimental conditions. Samples can be analyzed in gas, liquid, or solid forms. These techniques allow for a wide range of applications, like warfare agent detection, chemical reaction control, mass spectrometry imaging, polymer identification, and food safety monitoring, as well as applications in biomedical science, e.g., drug and pharmaceutical analysis, medical diagnostics, biochemical analysis, etc. Until now, the main drawback of plasma-based techniques is their quantitative aspect, but a lot of efforts have been done to improve this obstacle.
authors.affiliation: Faculty of Materials Science and Ceramics, Department of Biochemistry and Neurobiology, AGH University of Science and Technology, Mickiewicza 30, 30-059, Krakow, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Smoluch
authors.affiliation: Faculty of Materials Science and Ceramics, Department of Biochemistry and Neurobiology, AGH University of Science and Technology, Mickiewicza 30, 30-059, Krakow, Poland.|AGH University of Science and Technology, Academic Centre for Materials and Nanotechnology, Mickiewicza 30, 30-059, Krakow, Poland.
authors.forename: Przemyslaw
authors.initials: P
authors.lastname: Mielczarek
authors.affiliation: Faculty of Materials Science and Ceramics, Department of Biochemistry and Neurobiology, AGH University of Science and Technology, Mickiewicza 30, 30-059, Krakow, Poland.|Centre of Polymer and Carbon Materials, Polish Academy of Sciences, Curie-Sklodowskiej St. 34, 41-819, Zabrze, Poland.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Silberring
mesh_terms: D002623:Chemistry Techniques, Analytical / Q000379:methods*; D004867:Equipment Design; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D011312:Pressure; D015203:Reproducibility of Results; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods
keywords: ADI; ambient mass spectrometry; plasma-based ambient ionization; review