title: Biopeptides in Milk: Opiate and Antithrombotic Effects.
abstract: Recently, the concept of functional food can be seen worldwide, and there are several local wisdoms on health-conscious. In this context, the protein fractionation of\milk has attracted interests. Casein-derived bioactives have been identified as showing several health beneficial bioactivities including opiate, antithrombotic, antioxidative, antimicrobial, osteoprotective, anticariogenic and growth-promoting. Peptides have to be absorbed from the intestine and reach the target cells in sufficient concentrations or act via receptors; then they can show health effects. In this review paper, the milk-derived peptides and their therapeutic effects are introduced. Also the opiate and antithrombotic effects of these peptides are described.
authors.forename: Ramoona
authors.initials: R
authors.lastname: Masood
authors.affiliation: Department of Food Technology Research, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, P. O. Box 19395-4741, Tehran, Iran. kianoush.khosravi@nnftri.ac.ir.
authors.forename: Kianoush
authors.initials: K
authors.lastname: Khosravi-Darani
mesh_terms: D000701:Analgesics, Opioid / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D000818:Animals; D005343:Fibrinolytic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D008892:Milk / Q000378:metabolism*; D009292:Narcotic Antagonists / Q000737:chemistry / Q000378:metabolism; D010455:Peptides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects; D011485:Protein Binding; D011957:Receptors, Opioid / Q000819:agonists / Q000737:chemistry / Q000378:metabolism
chemical_list: D000701:Analgesics, Opioid; D005343:Fibrinolytic Agents; D009292:Narcotic Antagonists; D010455:Peptides; D011957:Receptors, Opioid