title: Combined thrombus aspiration and recanalization in treating Budd-Chiari syndrome with inferior vena cava thrombosis.
abstract: OBJECTIVE
  To investigate the feasibility, safety, and effectiveness of combined thrombus aspiration and inferior vena cava (IVC) recanalization for Budd-Chiari syndrome (BCS) patients with IVC thrombosis.
  
  
  METHODS
  From March 2011 to October 2014, 17 consecutive BCS patients with IVC thrombosis [male 13, female 4 (mean age 52.6 ± 8.4 years, range 43-72 years)] treated by combined thrombus aspiration and IVC recanalization were enrolled in this retrospective study. An 8F guiding catheter was used as the aspiration catheter. During the treatment, the aspiration catheter was placed from the right femoral vein to the IVC thrombi, and a 20-ml syringe was connected with the aspiration catheter for thrombus aspiration. IVC recanalization was performed after thrombus aspiration. Data on technical success, clinical success, and follow-up were analyzed.
  
  
  RESULTS
  Technical success was achieved in all patients. After thrombus aspiration, 12 patients had no visible thrombi on IVC venography, while 5 patients were shown to have the IVC mural thrombi. Afterwards, 13 patients were treated by IVC balloon dilation, and 4 patients were treated by IVC stent insertion. No patient experienced dyspnea after treatment. The average IVC pressure decreased from 29.8 ± 3.4 cmH2O to 8.6 ± 2.1 cmH2O (P < 0.001). Clinical success was achieved in all patients. The average follow-up period was 15.3 ± 11.6 months (range 2-44 months). Long-term IVC patency was achieved in 15 of 17 patients.
  
  
  CONCLUSIONS
  Combined thrombus aspiration and IVC recanalization can be a safe and effective method for BCS patients with IVC thrombosis.
authors.affiliation: Department of Radiology, Xuzhou Central Hospital, Xuzhou, China.
authors.forename: Yu-Fei
authors.initials: YF
authors.lastname: Fu
authors.affiliation: Department of Interventional Radiology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Xu
authors.affiliation: Department of Nuclear Medicine, Xuzhou Central Hospital, Xuzhou, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Wu
authors.affiliation: Department of Interventional Radiology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, China.
authors.forename: Qing-Qiao
authors.initials: QQ
authors.lastname: Zhang
authors.affiliation: Department of Interventional Radiology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, China.
authors.forename: Yan-Feng
authors.initials: YF
authors.lastname: Cui
authors.affiliation: Department of Interventional Radiology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, China. weiningjieru@163.com.
authors.forename: Ning
authors.initials: N
authors.lastname: Wei
mesh_terms: D000328:Adult; D000368:Aged; D006502:Budd-Chiari Syndrome / Q000150:complications / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019152:Paracentesis; D012189:Retrospective Studies; D013927:Thrombosis / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome; D014654:Vascular Patency; D014682:Vena Cava, Inferior
keywords: Aspiration; Budd–Chiari syndrome; Inferior vena cava; Thrombosis