title: Chondro-osseous respiratory epithelial adenomatoid hamartoma of the nasal cavity.
abstract: BACKGROUND
  Chondro-osseous respiratory epithelial adenomatoid hamartoma (COREAH) is a benign lesion of the nose and sinuses that is extremely rare, with only 2 cases reported in the literature to date.
  
  
  METHODS
  We present herein the third reported case of COREAH, in a 38-year-old woman who presented with left nasal obstruction and a mass in her left nasal cavity. The mass was completely resected endoscopically. Microscopic examination showed hamartomatous proliferation of respiratory-type glands with mucinous metaplasia admixed with numerous spicules of mature bone, characteristic of COREAH.
  
  
  CONCLUSIONS
  COREAH is a benign hamartomatous proliferation of respiratory epithelium, submucosal glands, and chondro-osseous mesenchyme. The clinical differential diagnoses for such lesions include glandular hamartoma, inflammatory polyp, inverted papilloma, and low-grade sinonasal adenocarcinoma. Recognition of this lesion as benign despite its potentially worrisome radiographic appearance is important to avoid an unnecessarily radical surgical procedure.
authors.affiliation: M.D. (Resident).
authors.forename: Faysal
authors.initials: F
authors.lastname: Fedda
authors.affiliation: M.D. (Assistant Professor).
authors.forename: Fouad
authors.initials: F
authors.lastname: Boulos
authors.affiliation: M.D. (Associate Professor).
authors.forename: Alain
authors.initials: A
authors.lastname: Sabri
keywords: hamartoma; nasal cavity; nasal polyps