title: FERONIA receptor kinase interacts with S-adenosylmethionine synthetase and suppresses S-adenosylmethionine production and ethylene biosynthesis in Arabidopsis.
abstract: Environmental inputs such as stress can modulate plant cell metabolism, but the detailed mechanism remains unclear. We report here that FERONIA (FER), a plasma membrane receptor-like kinase, may negatively regulate the S-adenosylmethionine (SAM) synthesis by interacting with two S-adenosylmethionine synthases (SAM1 and SAM2). SAM participates in ethylene, nicotianamine and polyamine biosynthetic pathways and provides the methyl group for protein and DNA methylation reactions. The Arabidopsis fer mutants contained a higher level of SAM and ethylene in plant tissues and displayed a dwarf phenotype. Such phenotype in the fer mutants was mimicked by over-expressing the S-adenosylmethionine synthetase in transgenic plants, whereas sam1/2 double mutant showed an opposite phenotype. We propose that FER receptor kinase, in response to environmental stress and plant hormones such as auxin and BR, interacts with SAM synthases and down-regulates ethylene biosynthesis.
authors.affiliation: NJU-NJFU Joint Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, 210093, China.|College of Life Sciences, Hunan Normal University, Changsha, 410081, China.
authors.forename: Dandan
authors.initials: D
authors.lastname: Mao
authors.affiliation: College of Life Sciences, Hunan Normal University, Changsha, 410081, China.|Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan University, Changsha, 410082, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Yu
authors.affiliation: College of Life Sciences, Hunan Normal University, Changsha, 410081, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.affiliation: Division of Mechatronics, Biostatistics and Sensors (MeBioS), Department of Biosystems (BIOSYST), KU Leuven, Leuven, 3001, Belgium.
authors.forename: Bram
authors.initials: B
authors.lastname: Van de Poel
authors.affiliation: National Institute of Biological Sciences, Beijing, 102206, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Tan
authors.affiliation: College of Life Sciences, Hunan Normal University, Changsha, 410081, China.
authors.forename: Jianglin
authors.initials: J
authors.lastname: Li
authors.affiliation: College of Life Sciences, Hunan Normal University, Changsha, 410081, China.
authors.forename: Yanqionq
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, Hunan University, Changsha, 410082, China.
authors.forename: Xiushang
authors.initials: X
authors.lastname: Li
authors.affiliation: National Institute of Biological Sciences, Beijing, 102206, China.
authors.forename: Mengqiu
authors.initials: M
authors.lastname: Dong
authors.affiliation: College of Life Sciences, Hunan Normal University, Changsha, 410081, China.
authors.forename: Liangbi
authors.initials: L
authors.lastname: Chen
authors.affiliation: College of Life Sciences, Hunan Normal University, Changsha, 410081, China.
authors.forename: Dongping
authors.initials: D
authors.lastname: Li
authors.affiliation: NJU-NJFU Joint Institute for Plant Molecular Biology, School of Life Sciences, Nanjing University, Nanjing, 210093, China.|Department of Plant and Microbial Biology, University of California, Berkeley, CA, 94720, USA.
authors.forename: Sheng
authors.initials: S
authors.lastname: Luan
mesh_terms: D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D060406:Brassinosteroids / Q000378:metabolism; D005030:Ethylenes / Q000378:metabolism; D018506:Gene Expression Regulation, Plant; D007210:Indoleacetic Acids / Q000378:metabolism; D008716:Methionine Adenosyltransferase / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D010770:Phosphotransferases; D010937:Plant Growth Regulators / Q000378:metabolism*; D030821:Plants, Genetically Modified; D011073:Polyamines / Q000378:metabolism; D012436:S-Adenosylmethionine / Q000378:metabolism*; D013260:Steroids, Heterocyclic / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases
chemical_list: D029681:Arabidopsis Proteins; D060406:Brassinosteroids; D005030:Ethylenes; D007210:Indoleacetic Acids; D008716:Methionine Adenosyltransferase; D010770:Phosphotransferases; D010937:Plant Growth Regulators; D011073:Polyamines; D012436:S-Adenosylmethionine; D013260:Steroids, Heterocyclic; C036216:ethylene; C522131:At3g51550 protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases; C023623:brassinolide
keywords: FER; SAM; metabolic regulation; signal transduction