title: Percutaneous Irreversible Electroporation of Unresectable Hilar Cholangiocarcinoma (Klatskin Tumor): A Case Report.
abstract: Irreversible electroporation (IRE) is a novel image-guided ablation technique that is rapidly gaining popularity in the treatment of malignant tumors located near large vessels or bile ducts. The presence of metal objects in the ablation zone, such as Wallstents, is generally considered a contraindication for IRE, because tissue heating due to power conduction may lead to thermal complications. This report describes a 66-year-old female with a Bismuth-Corlette stage IV unresectable cholangiocarcinoma with a metallic Wallstent in the common bile duct, who was safely treated with percutaneous IRE with no signs for relapse 1 year after the procedure.
authors.affiliation: Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. m.melenhorst@vumc.nl.
authors.forename: Marleen C A M
authors.initials: MC
authors.lastname: Melenhorst
authors.affiliation: Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. hj.scheffer@vumc.nl.
authors.forename: Hester J
authors.initials: HJ
authors.lastname: Scheffer
authors.affiliation: Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. la.vroomen@vumc.nl.
authors.forename: Laurien G P H
authors.initials: LG
authors.lastname: Vroomen
authors.affiliation: Department of Surgery, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. g.kazemier@vumc.nl.
authors.forename: Geert
authors.initials: G
authors.lastname: Kazemier
authors.affiliation: Department of Surgery, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. mp.vandentol@vumc.nl.
authors.forename: M Petrousjka
authors.initials: MP
authors.lastname: van den Tol
authors.affiliation: Department of Radiology and Nuclear Medicine, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. mr.meijerink@vumc.nl.
authors.forename: Martijn R
authors.initials: MR
authors.lastname: Meijerink
mesh_terms: D055011:Ablation Techniques / Q000379:methods; D000368:Aged; D001650:Bile Duct Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D001653:Bile Ducts, Intrahepatic / Q000000981:diagnostic imaging / Q000601:surgery; D018274:Electroporation / Q000379:methods*; D005260:Female; D006801:Humans; D018285:Klatskin Tumor / Q000000981:diagnostic imaging / Q000601:surgery*; D015641:Radiography, Interventional / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
keywords: Ablation techniques/adverse effects; Cholangiocarcinoma/Klatskin; Electroporation/methods; Irreversible electroporation (IRE); Tumor ablation/percutaneous