title: Pectic polysaccharides extracted from Rauvolfia verticillata (Lour.) Baill. var. hainanensis Tsiang increase LκB-α expression and ameliorate ulcerative colitis.
abstract: The therapeutic potential of pectic polysaccharides extracted from Rauvolfia verticillata (Lour.) Baill. var. hainanensis Tsiang in ulcerative colitis were investigated. This study showed that pectic polysaccharides extracted from Rauvolfia verticillata (Lour.) Baill. var. hainanensis Tsiang ameliorated ulcerative colitis and were proposed to exhibit anti-inflammatory effects via increased expression of IκB-α proteins and suppressing NF-αB translocation.
authors.forename: X P
authors.initials: XP
authors.lastname: Miao
authors.forename: X N
authors.initials: XN
authors.lastname: Sun
authors.forename: H
authors.initials: H
authors.lastname: Wei
authors.forename: Z J
authors.initials: ZJ
authors.lastname: Liu
authors.forename: L J
authors.initials: LJ
authors.lastname: Cui
authors.forename: T Z
authors.initials: TZ
authors.lastname: Deng
mesh_terms: D000818:Animals; D003093:Colitis, Ulcerative / Q000188:drug therapy* / Q000473:pathology; D003106:Colon / Q000473:pathology; D005260:Female; D020672:I-kappa B Proteins / Q000096:biosynthesis*; D051379:Mice; D008807:Mice, Inbred BALB C; D010368:Pectins / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D011134:Polysaccharides / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D011926:Rauwolfia / Q000737:chemistry*
chemical_list: D020672:I-kappa B Proteins; D011134:Polysaccharides; D010368:Pectins