title: Evaluation and management of amyotrophic lateral sclerosis.
abstract: Motor neuron diseases can cause progressive impairment of voluntary muscles of movement, respiration, speech, and swallowing. This review discusses the most common motor neuron disease, amyotrophic lateral sclerosis (ALS). It reviews the evaluation, diagnosis, and management of ALS, and its epidemiology, pathophysiology, and management. A coordinated approach by the primary care physician and neurologist is necessary with a focus on treatment options, durable medical equipment needs, and end-of-life discussions.
authors.affiliation: St. Francis Neurology, 2300-A Manchester Expressway, Suite 201, Columbus, GA 31904, USA. Electronic address: nvaladi@gmail.com.
authors.forename: Nojan
authors.initials: N
authors.lastname: Valadi
mesh_terms: D000223:Adaptation, Psychological; D000690:Amyotrophic Lateral Sclerosis / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D003937:Diagnosis, Differential; D004576:Electromyography; D020022:Genetic Predisposition to Disease; D006801:Humans; D008279:Magnetic Resonance Imaging; D011320:Primary Health Care / Q000379:methods*; D011788:Quality of Life; D012307:Risk Factors
keywords: Amyotrophic lateral sclerosis (ALS); Diagnostic criteria; Motor neuron disease (MND); Neurodegeneration; Neuromuscular disease