title: Modulatory effects on dendritic cells by human herpesvirus 6.
abstract: Human herpesvirus 6A and 6B are β-herpesviruses approaching 100% seroprevalance worldwide. These viruses are involved in several clinical syndromes and have important immunomodulatory effects. Dendritic cells (DC) are key players in innate and adaptive immunity. Accordingly, DC are implicated in the pathogenesis of many human diseases, including infections. In this review the effects of HHV-6 infection on DC will be discussed.
authors.affiliation: Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital Stockholm, Sweden.
authors.forename: Rasmus
authors.initials: R
authors.lastname: Gustafsson
authors.affiliation: Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Stockholm, Sweden.
authors.forename: Mattias
authors.initials: M
authors.lastname: Svensson
authors.affiliation: Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Stockholm, Sweden.
authors.forename: Anna
authors.initials: A
authors.lastname: Fogdell-Hahn
keywords: HHV-6; HLA; activation; co-stimulatory molecules; cytokines; dendritic cells