title: Ranolazine can markedly increase tacrolimus blood levels.
abstract: We report the case of a renal transplant patient on tacrolimus who developed a fully reversible renal failure and a doubling in serum tacrolimus closely associated with initiation of ranolazine (Ranexa) treatment, a new anti-angina drug recently introduced in Europe.
authors.affiliation: Nephrology Department , University Hospital Aristide Le Dantec , Dakar Senegal ; Nephrology, Hypertension and Renal Transplantation Unit, CNR-IBIM Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension , Ospedali Riuniti , Reggio Calabria, Italy.
authors.forename: Sidy
authors.initials: S
authors.lastname: Seck
authors.affiliation: Nephrology, Hypertension and Renal Transplantation Unit, CNR-IBIM Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension , Ospedali Riuniti , Reggio Calabria, Italy.
authors.forename: Marianna
authors.initials: M
authors.lastname: Bellantoni
authors.affiliation: Nephrology, Hypertension and Renal Transplantation Unit, CNR-IBIM Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension , Ospedali Riuniti , Reggio Calabria, Italy.
authors.forename: Carmine
authors.initials: C
authors.lastname: Zoccali
authors.affiliation: Nephrology, Hypertension and Renal Transplantation Unit, CNR-IBIM Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension , Ospedali Riuniti , Reggio Calabria, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Enia
keywords: Ranexa; interaction; ranolazine; tacrolimus