title: Advances in Anthrax Detection: Overview of Bioprobes and Biosensors.
abstract: Anthrax is an infectious disease caused by Bacillus anthracis. Although anthrax commonly affects domestic and wild animals, it causes a rare but lethal infection in humans. A variety of techniques have been introduced and evaluated to detect anthrax using cultures, polymerase chain reaction, and immunoassays to address the potential threat of anthrax being used as a bioweapon. The high-potential harm of anthrax in bioterrorism requires sensitive and specific detection systems that are rapid, field-ready, and real-time monitoring. Here, we provide a systematic overview of anthrax detection probes with their potential applications in various ultra-sensitive diagnostic systems.
authors.affiliation: Department of Oral Biochemistry and Molecular Biology, School of Dentistry, Kyung Hee University, Seoul, 130-701, South Korea.
authors.forename: Joungmok
authors.initials: J
authors.lastname: Kim
authors.forename: Vinayakumar
authors.initials: V
authors.lastname: Gedi
authors.forename: Sang-Choon
authors.initials: SC
authors.lastname: Lee
authors.forename: Jun-Haeng
authors.initials: JH
authors.lastname: Cho
authors.forename: Ji-Young
authors.initials: JY
authors.lastname: Moon
authors.forename: Moon-Young
authors.initials: MY
authors.lastname: Yoon
mesh_terms: D000818:Animals; D000881:Anthrax / Q000175:diagnosis* / Q000382:microbiology / Q000517:prevention & control*; D000907:Antibodies, Bacterial / Q000737:chemistry; D000942:Antigens, Bacterial / Q000032:analysis*; D052157:Aptamers, Nucleotide / Q000737:chemistry; D052158:Aptamers, Peptide / Q000737:chemistry; D001408:Bacillus anthracis / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D001427:Bacterial Toxins / Q000032:analysis*; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D023482:Bioterrorism / Q000517:prevention & control; D006801:Humans; D007118:Immunoassay / Q000379:methods; D058185:Magnetite Nanoparticles / Q000737:chemistry; D020135:Peptide Nucleic Acids / Q000737:chemistry; D016133:Polymerase Chain Reaction / Q000379:methods
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D052157:Aptamers, Nucleotide; D052158:Aptamers, Peptide; D001427:Bacterial Toxins; D058185:Magnetite Nanoparticles; D020135:Peptide Nucleic Acids; C030325:anthrax toxin