title: Malignant Rhabdoid Tumor with Cervical Vertebra Involvement in a Teenage Child: Case Report and Review of the Literature.
abstract: Malignant rhabdoid tumor (MRT) is a highly malignant and aggressive tumor associated with the kidney that is mainly seen in children under 5 years old, resulting in a rapid fatal outcome. MRT invasion of the cervical vertebra is an extremely rare form of this malignancy. This study presents a case of MRT involving the C4 vertebra and its appendix. A 13-year-old girl was found to have vague neck pain and a mass in the left neck area of the mid-cervical spine. Percutaneous needle biopsy was performed and the histological and immunohistochemical analysis pointed towards a rhabdoid tumor. Chemotherapy and radiotherapy were performed, but the tumor mass progressively enlarged. Tumorectomy was conducted followed by another 6 courses of chemotherapy and (125)I radioactive seed implantation. Unfortunately, the C4 vertebra and its appendix were found to be abnormal 3 months after the end of therapy. The patient received an additional tumorectomy, internal fixation with C4 reconstruction by a combined anterior and posterior approach, and 6 courses of consolidation chemotherapy. She is still alive 40 months since the initial diagnosis and remains asymptomatic 31 months after the surgery.
authors.affiliation: Department of Orthopedic Surgery, Affiliated Xinqiao Hospital, The Third Military Medical University, Chongqing, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Tang
authors.forename: Song
authors.initials: S
authors.lastname: Li
authors.forename: Jintao
authors.initials: J
authors.lastname: Qu
authors.forename: Yue
authors.initials: Y
authors.lastname: Zhou
authors.forename: Jianru
authors.initials: J
authors.lastname: Xiao
mesh_terms: D000293:Adolescent; D002574:Cervical Vertebrae / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D018335:Rhabdoid Tumor / Q000175:diagnosis* / Q000601:surgery*; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000601:surgery*