title: A novel citrinin derivative from the marine-source fungus Penicillium citrinum.
abstract: A novel citrinin derivative, penicitrinol L (1), along with two known analogues, penidicitrinin B (2) and pennicitrinone A (3) were isolated from the marine-source fungus Penicillium citrinum. The structure of the new compound was elucidated by spectroscopic methods including one and two-dimensional NMR as well as high-resolution mass spectrometric analysis. Furthermore, compound 1 showed modest cytotoxic activity against HL-60 cell line and compound 3 showed weak cytotoxic activity against A375 cell line.
authors.forename: Min
authors.initials: M
authors.lastname: Ni
authors.forename: Wei-Ling
authors.initials: WL
authors.lastname: Lin
authors.forename: Peng
authors.initials: P
authors.lastname: Yang
authors.forename: Shui-Chun
authors.initials: SC
authors.lastname: Mao
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification; D002953:Citrinin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D018922:HL-60 Cells; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D010407:Penicillium / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; C000604400:penicitrinol L; D002953:Citrinin