title: InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams.
abstract: BACKGROUND
  Set comparisons permeate a large number of data analysis workflows, in particular workflows in biological sciences. Venn diagrams are frequently employed for such analysis but current tools are limited.
  
  
  RESULTS
  We have developed InteractiVenn, a more flexible tool for interacting with Venn diagrams including up to six sets. It offers a clean interface for Venn diagram construction and enables analysis of set unions while preserving the shape of the diagram. Set unions are useful to reveal differences and similarities among sets and may be guided in our tool by a tree or by a list of set unions. The tool also allows obtaining subsets' elements, saving and loading sets for further analyses, and exporting the diagram in vector and image formats. InteractiVenn has been used to analyze two biological datasets, but it may serve set analysis in a broad range of domains.
  
  
  CONCLUSIONS
  InteractiVenn allows set unions in Venn diagrams to be explored thoroughly, by consequence extending the ability to analyze combinations of sets with additional observations, yielded by novel interactions between joined sets. InteractiVenn is freely available online at: www.interactivenn.net .
authors.affiliation: Universidade de São Paulo, Instituto de Ciências Matemáticas e de Computação, Av. Trabalhador São-carlense, 400, São Carlos SP, Brazil. henry@icmc.usp.br.
authors.forename: Henry
authors.initials: H
authors.lastname: Heberle
authors.affiliation: Laboratório Nacional de Biociências, Campinas SP, Caixa Postal 6192, Brazil. gabriela.meirelles@lnbio.cnpem.br.
authors.forename: Gabriela Vaz
authors.initials: GV
authors.lastname: Meirelles
authors.affiliation: Embrapa Informática Agropecuária, Av. André Tosello, 209, Campinas SP, Brazil. felipe.silva@embrapa.br.
authors.forename: Felipe R
authors.initials: FR
authors.lastname: da Silva
authors.affiliation: Universidade Estadual de Campinas, Instituto de Computação, Av. Albert Einstein, 1251, Campinas SP, Brazil. gpt@ic.unicamp.br.
authors.forename: Guilherme P
authors.initials: GP
authors.lastname: Telles
authors.affiliation: Universidade de São Paulo, Instituto de Ciências Matemáticas e de Computação, Av. Trabalhador São-carlense, 400, São Carlos SP, Brazil. rminghim@icmc.usp.br.
authors.forename: Rosane
authors.initials: R
authors.lastname: Minghim
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D019295:Computational Biology / Q000379:methods*; D003196:Computer Graphics; D003627:Data Interpretation, Statistical; D018745:Genome, Plant; D006801:Humans; D020407:Internet; D008297:Male; D028521:Musa / Q000737:chemistry / Q000378:metabolism; D010940:Plant Proteins / Q000032:analysis*; D011471:Prostatic Neoplasms / Q000378:metabolism; D040901:Proteomics; D012984:Software; D014407:Tumor Cells, Cultured
chemical_list: D014408:Biomarkers, Tumor; D010940:Plant Proteins