title: [IC-kmedoids: a clustering algorithm for RNA secondary structure prediction].
abstract: Due to the minimum free energy model, it is very important to predict the RNA secondary structure accurately and efficiently from the suboptimal foldings. Using clustering techniques in analyzing the suboptimal structures could effectively improve the prediction accuracy. An improved k-medoids cluster method is proposed to make this a better accuracy with the RBP score and the incremental candidate set of medoids matrix in this paper. The algorithm optimizes initial medoids through an expanding medoids candidate sets gradually. The predicted results indicated this algorithm could get a higher value of CH and significantly shorten the time for calculating clustering RNA folding structures.
authors.forename: Changwu
authors.initials: C
authors.lastname: Wang
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Liu
authors.forename: Baowen
authors.initials: B
authors.lastname: Wang
authors.forename: Wenyuan
authors.initials: W
authors.lastname: Liu
mesh_terms: D000465:Algorithms; D016000:Cluster Analysis; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*
chemical_list: D012313:RNA