title: [A model of primary open-angle glaucoma: manifestations and outcomes].
abstract: OBJECTIVE
  To determine the expected duration of the disease and the age of the patients with different stages ofprimary open-angle glaucoma complicated by pseudoexfoliation syndrome (PES) and/or patients with pseudoexfoliation glaucoma (PEG).
  
  
  METHODS
  The study protocol included data from 120 patients (50 males (41.7%), 70 females (58.3%)); 189 eyes; 102 right eyes; 87 left eyes). The first study group (28 patients, 44 eyes) comprised patients with suspected glaucoma. The second group (53 patients, 84 eyes) consisted ofpatients with early glaucoma. The third group (21 patient, 33 eyes) included patients with advanced glaucoma, the forth group (18 patients, 28 eyes) comprised patients with terminal glaucoma. Mean age of the patients at diagnosis was 61.6 (58.4; 66.9) years and 66.9 (63.4; 72.8) years at the endpoint visit in 2013. In all cases, diagnosis was made in accordance with the differential diagnostics system and confirmed by special diagnostic techniques. The database included data from 3 qualified examinations taking account of the results of tonometry and static automated perimetry.
  
  
  RESULTS
  The mean expected age of the patients age at the onset of blindness was 75.1 years. The occurrence of the event was limited to a period of 6.1 years. Mean age at the time of possible glaucoma development was 59.58 (56.14; 64.36) years. The disease itself could develop within 3.24 (-5.38; -1.2) years prior to diagnosis.
  
  
  CONCLUSIONS
  Studies for glaucoma diagnosis should be focused on the age group of 55-60 years. The degree of IOP reduction in patients with advanced glaucoma does not agree with the Russian glaucoma society recommendations which accounts for progression of the disease.
authors.forename: R V
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authors.lastname: Andeev
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authors.lastname: Alexandrov
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authors.lastname: Garkavenko
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authors.lastname: Getmanova
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authors.initials: VV
authors.lastname: Gorodnichy
authors.forename: M S
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authors.lastname: Gorshkova
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authors.lastname: Gusarevitch
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authors.initials: DA
authors.lastname: Dorofeev
authors.forename: S A
authors.initials: SA
authors.lastname: Zhavoronkov
authors.forename: P Ch
authors.initials: PCh
authors.lastname: Zavadski
authors.forename: O G
authors.initials: OG
authors.lastname: Zvereva
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authors.initials: UR
authors.lastname: Karimov
authors.forename: A V
authors.initials: AV
authors.lastname: Kulik
authors.forename: A V
authors.initials: AV
authors.lastname: Kuroyedov
authors.forename: S N
authors.initials: SN
authors.lastname: Lanin
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authors.initials: DN
authors.lastname: Lovpache
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authors.initials: IA
authors.lastname: Loskutov
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authors.initials: EV
authors.lastname: Molchanova
authors.forename: V Yu
authors.initials: VY
authors.lastname: Ogorodnikova
authors.forename: O N
authors.initials: ON
authors.lastname: Onufrichuk
authors.forename: S Yu
authors.initials: SY
authors.lastname: Petrov
authors.forename: Yu I
authors.initials: YI
authors.lastname: Razhko
authors.forename: T A
authors.initials: TA
authors.lastname: Sidenko
mesh_terms: D017668:Age of Onset; D000368:Aged; D018450:Disease Progression; D017889:Exfoliation Syndrome / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012720:Severity of Illness Index