title: Erythrocyte polyunsaturated fatty acid levels in young people at ultra-high risk for psychotic disorder and healthy adolescent controls.
abstract: Erythrocyte polyunsaturated fatty acid (PUFA) levels from individuals at ultra-high risk (UHR) for psychosis (n = 80) were compared to existing data from healthy controls (n = 142). Results demonstrated PUFA deficits (α-linolenic acid, eicosapentanoic acid, all ω-6 PUFAs) for the UHR group. Findings provide a rationale for PUFA based interventions in emerging psychosis.
authors.affiliation: Orygen, The National Centre of Excellence in Youth Mental Health, Centre for Youth Mental Health, The University of Melbourne, Australia.
authors.forename: Simon M
authors.initials: SM
authors.lastname: Rice
authors.affiliation: Orygen, The National Centre of Excellence in Youth Mental Health, Centre for Youth Mental Health, The University of Melbourne, Australia.
authors.forename: Miriam R
authors.initials: MR
authors.lastname: Schäfer
authors.affiliation: Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
authors.forename: Claudia
authors.initials: C
authors.lastname: Klier
authors.affiliation: Department of Psychiatry and Psychotherapy, Clinical Division of Social Psychiatry, Medical University Vienna, Austria.
authors.forename: Nilufar
authors.initials: N
authors.lastname: Mossaheb
authors.affiliation: Orygen, The National Centre of Excellence in Youth Mental Health, Centre for Youth Mental Health, The University of Melbourne, Australia; Melbourne School of Psychological Sciences, The University of Melbourne, Australia.
authors.forename: Nandita
authors.initials: N
authors.lastname: Vijayakumar
authors.affiliation: Orygen, The National Centre of Excellence in Youth Mental Health, Centre for Youth Mental Health, The University of Melbourne, Australia. Electronic address: amminger@unimelb.edu.au.
authors.forename: Günter Paul
authors.initials: GP
authors.lastname: Amminger
mesh_terms: D000293:Adolescent; D000328:Adult; D004912:Erythrocytes / Q000378:metabolism*; D015525:Fatty Acids, Omega-3 / Q000097:blood*; D043371:Fatty Acids, Omega-6 / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000097:blood*; D012306:Risk; D055815:Young Adult
chemical_list: D015525:Fatty Acids, Omega-3; D043371:Fatty Acids, Omega-6
keywords: Polyunsaturated fatty acids; Psychosis; Ultra-high risk