title: Neuropathies after surgery: Anatomical considerations of pathologic mechanisms.
abstract: Positioning-related injuries caused during surgery under anesthesia are most likely multifactorial. Pathologic mechanical forces alone (overstretching and/or ischemia from direct compression) may not fully explain postsurgical neuropathy with recent evidence implicating patient-specific factors or perioperative inflammatory responses spatially and even temporally divorced from the anatomical region of injury. The aim of this introductory article is to provide an overview of anatomic considerations of these mechanical forces on soft and nervous tissues along with factors that may compound compression or stretch injury. Three subsequent articles will address specific positioning-related anatomic considerations of the (1) upper extremities, (2) lower extremities, and (3) central nervous system and soft tissues.
authors.affiliation: Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota, 55905.
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Johnson
authors.affiliation: Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota, 55905.
authors.forename: Mary E
authors.initials: ME
authors.lastname: Warner
authors.affiliation: Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, 55905.
authors.forename: Nathan P
authors.initials: NP
authors.lastname: Staff
authors.affiliation: Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota, 55905.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Warner
mesh_terms: D006801:Humans; D056888:Patient Positioning / Q000009:adverse effects; D010525:Peripheral Nerves / Q000033:anatomy & histology*; D010523:Peripheral Nervous System Diseases / Q000473:pathology*; D011183:Postoperative Complications; D017695:Soft Tissue Injuries / Q000473:pathology
keywords: patient positioning; perioperative care; peripheral nerve injuries