title: Effects of Retinal Angiography on Optical Coherence Tomography Measurements.
abstract: OBJECTIVE
  To evaluate the effects of retinal angiography, using fluorescein and indocyanine green dyes, on optical coherence tomography (OCT) measurements.
  
  
  METHODS
  In total, 76 eyes from 76 consecutive patients were included. Macular cube 512 × 128 combination scanning and optic disc 200 × 200 scanning using spectral-domain (SD)-OCT were performed twice, before and after retinal angiography, with fluorescein or indocyanine green. Signal strength, regional retinal thickness of the 9 Early Treatment Diabetic Retinopathy Study subfields, total macular volume, and retinal nerve fiber layer thickness obtained before and after angiography were compared. Repeatability was also investigated.
  
  
  RESULTS
  Comparing the results of OCT measured before and after retinal angiography, there was no statistically significant difference in any parameter assessed. The interclass correlation values for each measurement were all >0.808 (range 0.808-0.999).
  
  
  CONCLUSIONS
  Retinal angiography using fluorescein and indocyanine green dyes has no significant effect on OCT measurements.
authors.affiliation: Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
authors.forename: Young-Joon
authors.initials: YJ
authors.lastname: Jo
authors.forename: Hyung-Bin
authors.initials: HB
authors.lastname: Lim
authors.forename: Soo-Hyun
authors.initials: SH
authors.lastname: Lee
authors.forename: Jung-Yeul
authors.initials: JY
authors.lastname: Kim
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000033:anatomy & histology; D002829:Choroid / Q000033:anatomy & histology; D015862:Choroid Diseases / Q000175:diagnosis; D004396:Coloring Agents / Q000008:administration & dosage; D005123:Eye / Q000033:anatomy & histology*; D005260:Female; D019793:Fluorescein / Q000008:administration & dosage*; D005451:Fluorescein Angiography; D005456:Fluorescent Dyes / Q000008:administration & dosage; D006801:Humans; D007208:Indocyanine Green / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012160:Retina / Q000033:anatomy & histology; D012164:Retinal Diseases / Q000175:diagnosis; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D014822:Vitreous Body / Q000033:anatomy & histology
chemical_list: D004396:Coloring Agents; D005456:Fluorescent Dyes; D007208:Indocyanine Green; D019793:Fluorescein