title: Analysis of anaphylactic shock caused by 17 types of traditional Chinese medicine injections used to treat cardiovascular and cerebrovascular diseases.
abstract: Several reports describing anaphylactic shock following treatment of cardiovascular and cerebrovascular diseases with Chinese herbal injections were described. Our analysis of these reports showed that anaphylactic shock caused by traditional Chinese medicine (TCM) injections for the treatment of cardiovascular and cerebrovascular diseases is common but also sometimes fatal. Therefore, we proposed the following four suggestions for improving the clinical safety of delivering Chinese herbal injections and reducing the occurrence of allergic shock. First, patients with cardiovascular and cerebrovascular diseases are at high risk, so they should only be given TCM injections after a doctor's diagnosis and approval. Second, people in allergic groups can suffer anaphylactic shock, so vigilance is important in the treatment of all age groups, although even more caution should be exercised when treating children or elderly people. In fact, TCM injections may not be appropriate for those age groups, so that they should be carefully considered before treatment. Third, no significant gender differences have been noted in patients with anaphylactic shock, so all patients should be carefully monitored, irrespective of gender. Fourth, the timeframe in which different drugs cause anaphylactic shock varies; thus, patients should be observed as long as possible.
authors.affiliation: Department of Pharmacology, The First Affiliate Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
authors.forename: Yu-Jiao
authors.initials: YJ
authors.lastname: Guo
authors.affiliation: Department of Pharmacology, The First Affiliate Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
authors.forename: De-Wang
authors.initials: DW
authors.lastname: Wang
authors.affiliation: Department of Pharmacology, The First Affiliate Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
authors.forename: Ling
authors.initials: L
authors.lastname: Meng
authors.affiliation: Department of Pharmacology, The First Affiliate Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
authors.forename: Yong-Qing
authors.initials: YQ
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced*; D002318:Cardiovascular Diseases / Q000188:drug therapy*; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal