title: Osseous and dental outcomes of primary gingivoperiosteoplasty with iliac bone graft: A radiological evaluation.
abstract: Primary alveolar cleft repair has two main purposes: to restore normal morphology and normal function. Gingivoperiosteoplasty with bone grafting in mixed dentition has been a well-established procedure. We hypothesized that 1) performance of this surgery in deciduous dentition would provide favorable bone graft osseointegration, and 2) would improve the support of incisor teeth eruption, thereby avoiding maxillary growth disturbances. We conducted a retrospective study of clinical and tridimensional radiological data for 73 patients with alveolar clefts (with or without lip and palate clefts) who underwent gingivoperiosteoplasty with iliac bone graft in deciduous dentition. Pre- and post-operative Cone Beam Computed Tomography (CBCT) comparison allowed evaluation of the ratio between bone graft volume and initial cleft volume (BGV/ICV ratio), and measurement of central incisor teeth movements. This series of 73 patients included 44 males and 29 females, with a mean age of 5.5 years. Few complications were observed. Post-operative CBCT was performed at 7.4 months. The mean BGV/ICV ratio was 0.62. Axial rotation was significantly improved post-operatively (p = 0.004). Gingivoperiosteoplasty with iliac bone graft is safe when performed in deciduous dentition and results in a sufficient bone graft volume to support lateral incisor eruption and upper central incisor tooth position improvement.
authors.affiliation: Université Lille Nord de France, UDSL, F-59000, Lille, France; Oral and Maxillofacial Department, Roger Salengro Hospital, University Hospital of Lille, F-59000, Lille, France; INSERM U 1008, Controlled Drug Delivery Systems and Biomaterials, F-59000, Lille, France. Electronic address: sandrine.touzet@gmail.com.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Touzet-Roumazeille
authors.affiliation: APHP, Hôpital Necker-Enfants Malades, Service de chirurgie maxillo-faciale, F-75015, Paris, France; Centre de référence des malformations de la face et de la cavité buccale, F-75015, Paris, France; Université Paris VII, Faculté de Médecine Diderot, F-75006, Paris, France.
authors.forename: Brigitte
authors.initials: B
authors.lastname: Vi-Fane
authors.affiliation: APHP, Hôpital Necker-Enfants Malades, Service de chirurgie maxillo-faciale, F-75015, Paris, France; Université Paris V, Faculté de Médecine Paris Descartes, F-75006, Paris, France; Centre de référence des malformations de la face et de la cavité buccale, F-75015, Paris, France; Laboratoire de Physiopathologie orale et Moléculaire, INSERM, UMRS 872, Equipe 5, Centre de recherche des Cordeliers, 75006, Paris, France.
authors.forename: Natacha
authors.initials: N
authors.lastname: Kadlub
authors.affiliation: Biostatistic Unit, EA2694, Hospital and University Lille Nord de France, France.
authors.forename: Michaël
authors.initials: M
authors.lastname: Genin
authors.affiliation: APHP, Hôpital Necker-Enfants Malades, Service de chirurgie maxillo-faciale, F-75015, Paris, France.
authors.forename: Caroline
authors.initials: C
authors.lastname: Dissaux
authors.affiliation: Université Lille Nord de France, UDSL, F-59000, Lille, France; Oral and Maxillofacial Department, Roger Salengro Hospital, University Hospital of Lille, F-59000, Lille, France; INSERM U 1008, Controlled Drug Delivery Systems and Biomaterials, F-59000, Lille, France.
authors.forename: Gwenaël
authors.initials: G
authors.lastname: Raoul
authors.affiliation: Université Lille Nord de France, UDSL, F-59000, Lille, France; Oral and Maxillofacial Department, Roger Salengro Hospital, University Hospital of Lille, F-59000, Lille, France; INSERM U 1008, Controlled Drug Delivery Systems and Biomaterials, F-59000, Lille, France.
authors.forename: Joël
authors.initials: J
authors.lastname: Ferri
authors.affiliation: APHP, Hôpital Necker-Enfants Malades, Service de chirurgie maxillo-faciale, F-75015, Paris, France; Université Paris V, Faculté de Médecine Paris Descartes, F-75006, Paris, France; Centre de référence des malformations de la face et de la cavité buccale, F-75015, Paris, France; Laboratoire de Physiopathologie orale et Moléculaire, INSERM, UMRS 872, Equipe 5, Centre de recherche des Cordeliers, 75006, Paris, France.
authors.forename: Marie-Paule
authors.initials: MP
authors.lastname: Vazquez
authors.affiliation: APHP, Hôpital Necker-Enfants Malades, Service de chirurgie maxillo-faciale, F-75015, Paris, France; Centre de référence des malformations de la face et de la cavité buccale, F-75015, Paris, France; Université Paris VI, Faculté de Médecine Pierre et Marie Curie, F-75005, Paris, France; Laboratoire de Physiopathologie orale et Moléculaire, INSERM, UMRS 872, Equipe 5, Centre de recherche des Cordeliers, 75006, Paris, France.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Picard
mesh_terms: D064728:Alveolar Bone Grafting / Q000379:methods*; D064592:Autografts / Q000637:transplantation; D016025:Bone Transplantation / Q000379:methods*; D002675:Child, Preschool; D002971:Cleft Lip / Q000601:surgery; D002972:Cleft Palate / Q000601:surgery; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D003481:Cuspid / Q000033:anatomy & histology; D005260:Female; D005500:Follow-Up Studies; D005893:Gingivoplasty / Q000379:methods*; D006801:Humans; D007085:Ilium / Q000601:surgery; D007091:Image Processing, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods; D007180:Incisor / Q000502:physiology; D008297:Male; D009929:Organ Size; D010155:Palatal Expansion Technique; D010521:Periosteum / Q000000981:diagnostic imaging / Q000601:surgery*; D012189:Retrospective Studies; D014078:Tooth Eruption / Q000502:physiology; D014094:Tooth, Deciduous; D060053:Transplant Donor Site / Q000601:surgery; D016896:Treatment Outcome
keywords: Alveolar bone grafting; Cleft lip with or without cleft palate; Cone-beam computed tomography; Three-dimensional imaging