title: Longitudinal Evaluation of the Structural Integrity of Teeth Affected by Molar Incisor Hypomineralisation.
abstract: The aim of this prospective cohort study was to evaluate the risk of posteruptive breakdown and the development of caries lesions in teeth with molar incisor hypomineralisation (MIH). A total of 367 permanent incisors and first molars, affected and not affected by MIH lesions, of 45 children with MIH from Araraquara, São Paulo, Brazil, were evaluated at intervals from 6 to 12 months by assessing the severity of MIH, the presence of tooth caries lesions and the treatment needed. During the study period, all patients received preventive care. The data were analysed using Fisher's exact test and actuarial method survival analysis. Significant associations were also found in teeth between the presence of MIH and a DMFT index >0 in all periods and also between the need for treatment and the presence of MIH. The teeth affected by MIH opacities were healthy in 99% of incisors and 93% of molars at the end of the 12-month period. Due to the high likelihood of maintaining the tooth structure in opacities, the complete or premature removal of the affected area is not justified.
authors.affiliation: Department of Pediatric Dentistry and Orthodontics, Araraquara School of Dentistry, UNESP, Universidade Estadual Paulista, São Paulo, Brazil.
authors.forename: Camila Maria
authors.initials: CM
authors.lastname: Bullio Fragelli
authors.forename: Fabiano
authors.initials: F
authors.lastname: Jeremias
authors.forename: Juliana
authors.initials: J
authors.lastname: Feltrin de Souza
authors.forename: Marco Aurélio
authors.initials: MA
authors.lastname: Paschoal
authors.forename: Rita
authors.initials: R
authors.lastname: de Cássia Loiola Cordeiro
authors.forename: Lourdes
authors.initials: L
authors.lastname: Santos-Pinto
mesh_terms: D002327:Cariostatic Agents / Q000627:therapeutic use; D002648:Child; D015331:Cohort Studies; D004245:DMF Index; D003743:Dental Enamel / Q000473:pathology; D003744:Dental Enamel Hypoplasia / Q000145:classification* / Q000517:prevention & control; D005260:Female; D005460:Fluorides, Topical / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007180:Incisor / Q000473:pathology*; D008137:Longitudinal Studies; D008297:Male; D008963:Molar / Q000473:pathology*; D020380:Needs Assessment; D023861:Photography, Dental / Q000379:methods; D011446:Prospective Studies; D018570:Risk Assessment; D014082:Tooth Fractures / Q000145:classification
chemical_list: D002327:Cariostatic Agents; D005460:Fluorides, Topical