title: Hemoperitoneum from corpus luteum rupture in patients with aplastic anemia.
abstract: BACKGROUND
  Aplastic anemia is a rare hematopoietic stem-cell disorder that results in pancytopenia and hypocellular bone marrow. Women with aplastic anemia usually are at increased risk of corpus luteum rupture due to thrombocytopenia and infection.
  
  
  METHODS
  Here we report two cases had hemoperitoneum from corpus luteum rupture in patients with aplastic anemia in our center.
  
  
  RESULTS
  Case 1 involved two episodes of hemoperitoneum resulting from rupture of the corpus luteum in a 23-year-old unmarried female with severe aplastic anemia. This patient was managed conservatively with platelet and packed red cell transfusion. Case 2 involved two episodes of hemoperitoneum resulting from rupture of the corpus luteum in a 33-year-old married patient with aplastic anemia. Emergency laparoscopy revealed massive hemoperitoneum. Bilateral salpingo-oophorectomy were performed successively with platelet and packed red cell transfusion.
  
  
  CONCLUSIONS
  Hemoperitoneum resulting from a ruptured corpus luteum is a life-threatening condition in patients with aplastic anemia. Prompt and appropriate evaluation of corpus luteum rupture and emergent therapy are needed.
authors.forename: Huaquan
authors.initials: H
authors.lastname: Wang
authors.forename: Lifang
authors.initials: L
authors.lastname: Guo
authors.forename: Zonghong
authors.initials: Z
authors.lastname: Shao
mesh_terms: D000328:Adult; D000741:Anemia, Aplastic / Q000150:complications* / Q000503:physiopathology*; D003338:Corpus Luteum / Q000473:pathology*; D005260:Female; D006465:Hemoperitoneum / Q000473:pathology*; D006470:Hemorrhage; D006801:Humans; D012307:Risk Factors; D012421:Rupture; D055815:Young Adult