title: Microscopic enteritis and pathomechanism of malabsorption.
abstract: Microscopic enteritis (ME) is the stage of microscopic and sub-microscopic changes (microenteropathy) associated with the symptoms of gluten sensitive enteropathy leading to micronutrient deficiencies. It is characterized by subtle mucosal abnormalities without prominent inflammation, villous effacement, erosions or ulcerations on conventional light microscopy. The intraepithelial lymphocytes are usually in normal range <25/100 enterocytes (microenteropathy) or increased (lymphocytic enteritis). ME is the entity behind atypical forms of CD previously known as potential and latent CD. Systemic inflammation predominantly is found to be engaged in pathophysiology of micro-nutrient deficiency even in absence of macroscopic mucosal changes.
authors.affiliation: School of Medicine, University of Birmingham, Birmingham, UK.
authors.forename: Kamran
authors.initials: K
authors.lastname: Rostami
authors.affiliation: Department of Gastroenterology, Alexander Hospital, Redditch, UK.
authors.forename: David
authors.initials: D
authors.lastname: Al Dulaimi
authors.affiliation: Research Center of Gastroenterology and Liver disease, Shaheed Beheshti University M.C., Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Rostami Nejad
authors.affiliation: 2nd Department of Pathology, Spedali Civili, University of Brescia, Brescia, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Villanacci
authors.affiliation: "Gr. T. Poparrd University of Medicine and Pharmacy, Iasi, Romania.
authors.forename: Mihai
authors.initials: M
authors.lastname: Danciu
keywords: Coeliac disease; Cytokine; Gluten sensitivity; Malabsorption; Microscopic enteritis; Physiopathology