title: [Epidemiological characteristics and risk factors for patients with catheter-related bloodstream infections in intensive care unit].
abstract: OBJECTIVE
  To explore the epidemiological characteristics, bacterial composition and risk factors for patients with catheter-related bloodstream infection (CRBSI) in intensive care unit (ICU).
  
  
  METHODS
  A prospective survey was conduced for 2 605 ICU patients during January 2010 to December 2013. The clinical data of CRBSI and non-CRBSI patients were compared and their relevant risk factors analyzed.
  
  
  RESULTS
  Among them, there were 1 773 cases of arteriovenous catheterization. And 94 cases (5.3%) had CRBSI. The 1 000-day catheter infection rate was 9.8. The mortality rates of CRBSI and non-CRBSI patients were 23.4% and 10.7% respectively. And the difference was statistically significant (χ² = 14.38, P < 0.01). The occurrence of CRBSI was a risk factor for mortality. Logistic regression analysis showed that the occurrence of CRBSI was 3.33 folds for venous catheterization time > 6 days over ≤ 6 days (95% CI: 2.04-5.56), 2.50 folds for trauma patients over non-trauma ones (95% CI: 1.49-4.17), 2.98 folds for malignant tumors patients over non-malignant tumors ones (95% CI: 1.61-5.51) and 4.32 folds for diabetics over non-diabetics (95% CI: 2.07-9.01). For different sites of arteriovenous catheterization, the occurrences of CRBSI were not statistically significant. For CRBSI patients with blood culture, the positive microorganisms were gram-negative bacteria (61.7%), gram-positive bacteria (26%) and fungi (12.3%).
  
  
  CONCLUSIONS
  The occurrence of CRBSI is a risk factor for mortality. And diabetes, trauma and arteriovenous catheterization time > 6 days are risk factors for CRBSI. Comprehensive preventive measures should be taken to reduce the incidence of CRBSI.
authors.affiliation: Department of Nosocomial Infection, First Municipal Hospital, Jiaxing 314000, China; Email: jialei1839@163.com.
authors.forename: Lei
authors.initials: L
authors.lastname: Jia
authors.forename: Huijie
authors.initials: H
authors.lastname: Yu
authors.forename: Jinqi
authors.initials: J
authors.lastname: Lu
authors.forename: Yuqi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Ying
authors.initials: Y
authors.lastname: Cai
authors.forename: Yuting
authors.initials: Y
authors.lastname: Liu
authors.forename: Xiefeng
authors.initials: X
authors.lastname: Ma
mesh_terms: D016470:Bacteremia; D055499:Catheter-Related Infections; D002405:Catheterization, Central Venous; D005658:Fungi; D006090:Gram-Negative Bacteria; D006094:Gram-Positive Bacteria; D006801:Humans; D015994:Incidence; D007362:Intensive Care Units; D011446:Prospective Studies; D012307:Risk Factors; D013997:Time Factors