title: The ketogenic diet in pharmacoresistant childhood epilepsy.
abstract: Available pharmacologic treatments for seizures are limited in their efficacy. For a patient with seizures, pharmacologic treatment with available anticonvulsant medications leads to seizure control in <70% of patients. Surgical resection can lead to control in a select subset of patients but still leaves a significant number of patients with uncontrolled seizures. The ketogenic diet and related diets have proven to be useful in pharmacoresistant childhood epilepsy.
authors.affiliation: Johns Hopkins All Children's Hospital, Johns Hopkins University, University of South Florida, 501 Sixth Street South, Suite 511, Saint Petersburg, FL 33701, USA.
authors.forename: Steven Parrish
authors.initials: SP
authors.lastname: Winesett
authors.forename: Stacey Kordecki
authors.initials: SK
authors.lastname: Bessone
authors.forename: Eric H W
authors.initials: EH
authors.lastname: Kossoff
mesh_terms: D002648:Child; D055423:Diet, Ketogenic / Q000379:methods*; D000069279:Drug Resistant Epilepsy / Q000178:diet therapy*; D006801:Humans
keywords: GLUT-1 deficiency; MCT diet; doose syndrome; epilepsy; infantile spasms; ketogenic; lennox-gastaut syndrome; low glycemic index diet; modified atkins diet; seizures