title: Evaluation and management of head and neck squamous cell carcinoma of unknown primary.
abstract: The diagnostic evaluation and therapeutic management of a patient with squamous cell carcinoma of an unknown primary (SCCUP) has considerably evolved over recent decades and will likely continue to change as a result of the improving ability to identify small primary tumors and better tailor the implementation of multimodality therapy. By application of the general principles of head and neck oncology, physicians and surgeons are often able to achieve satisfactory control of the disease in patients with SCCUP.
authors.affiliation: Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Martin
authors.affiliation: Department of Radiation Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA. Electronic address: Thomas.galloway@fccc.edu.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Galloway
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D003131:Combined Modality Therapy; D019468:Disease Management; D006258:Head and Neck Neoplasms / Q000628:therapy*; D006801:Humans; D009382:Neoplasms, Unknown Primary / Q000628:therapy*; D011379:Prognosis
keywords: Head and neck cancer; Radiation therapy; Squamous cell carcinoma; Surgery; Unknown primary