title: Magnesium Status and Its Relationship with C-Reactive Protein in Obese Women.
abstract: This study assessed the relationship between magnesium status and C-reactive protein concentration in obese and nonobese women. This cross-sectional study included 131 women, aged between 20 and 50 years, who were divided into two groups: obese (n=65) and control (n=66) groups. Magnesium intake was monitored using 3-day food records and NutWin software version 1.5. The plasma, erythrocyte, and urinary magnesium concentrations were determined by flame atomic absorption spectrophotometry. C-reactive protein concentration in serum was measured by immunoturbidimetric assay. The mean values of the magnesium content in the diet were lower than those recommended, though there was no significant difference between groups (p>0.05). The mean concentrations of plasma and erythrocyte magnesium were within the normal range, with no significant difference between groups (p>0.05). Urinary excretion of this mineral was less than the reference values in both groups, with no significant difference (p>0.05). The mean concentration of serum C-reactive protein was within the normal range in both groups, with no significant difference (p>0.05). There was a positive correlation between urinary magnesium and serum C-reactive protein (p=0.015). Obese patients ingest low dietary magnesium content, which seems to induce hypomagnesuria as a compensatory mechanism to keep plasma concentrations of the mineral at adequate levels. The study shows a positive correlation between urinary magnesium concentrations and serum C-reactive protein, suggesting the influence of hypomagnesuria on this inflammatory protein in obese women.
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Ana Raquel Soares
authors.initials: AR
authors.lastname: de Oliveira
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Kyria Jayanne Clímaco
authors.initials: KJ
authors.lastname: Cruz
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Jennifer Beatriz Silva
authors.initials: JB
authors.lastname: Morais
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Juliana Soares
authors.initials: JS
authors.lastname: Severo
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Taynáh Emannuelle Coelho
authors.initials: TE
authors.lastname: de Freitas
authors.affiliation: Clinical Pathology Laboratory Antonio Lobão, Teresina, Piauí, Brazil.
authors.forename: Antonio Lobão
authors.initials: AL
authors.lastname: Veras
authors.affiliation: Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, Butantã, São Paulo, São Paulo, Brazil.
authors.forename: Amanda Batista
authors.initials: AB
authors.lastname: da Rocha Romero
authors.affiliation: Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, Butantã, São Paulo, São Paulo, Brazil.
authors.forename: Célia
authors.initials: C
authors.lastname: Colli
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Nadir
authors.initials: N
authors.lastname: do Nascimento Nogueira
authors.affiliation: Department of Physiology and Biophysics, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Francisco Leonardo
authors.initials: FL
authors.lastname: Torres-Leal
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil. dilina.marreiro@gmail.com.
authors.forename: Dilina
authors.initials: D
authors.lastname: do Nascimento Marreiro
mesh_terms: D000328:Adult; D000886:Anthropometry; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000378:metabolism*; D003430:Cross-Sectional Studies; D004032:Diet; D005260:Female; D006801:Humans; D007249:Inflammation / Q000097:blood; D008274:Magnesium / Q000097:blood* / Q000652:urine; D008875:Middle Aged; D009752:Nutritional Status; D009765:Obesity / Q000097:blood*; D015203:Reproducibility of Results; D013054:Spectrophotometry, Atomic; D055815:Young Adult
chemical_list: D002097:C-Reactive Protein; D008274:Magnesium
keywords: C-Reactive protein; Magnesium; Nutritional status; Obesity