title: 2015 UK National Guideline on the management of non-gonococcal urethritis.
abstract: We present the updated British Association for Sexual Health and HIV guideline for the management of non-gonococcal urethritis in men. This document includes a review of the current literature on its aetiology, diagnosis and management. In particular it highlights the emerging evidence that azithromycin 1 g may result in the development of antimicrobial resistance in Mycoplasma genitalium and that neither azithromycin 1 g nor doxycycline 100 mg twice daily for seven days achieves a cure rate of >90% for this micro-organism. Evidence-based diagnostic and management strategies for men presenting with symptoms suggestive of urethritis, those confirmed to have non-gonococcal urethritis and those with persistent symptoms following first-line treatment are detailed.
authors.affiliation: School of social and Community Medicine, University of Bristol, Bristol, UK Bristol Sexual Health Centre, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
authors.forename: P
authors.initials: P
authors.lastname: Horner
authors.affiliation: Bristol Sexual Health Centre, University Hospitals Bristol NHS Foundation Trust, Bristol, UK.
authors.forename: K
authors.initials: K
authors.lastname: Blee
authors.affiliation: Chester Sexual Health, Countess of Chester NHS Foundation Trust, Cheshire, UK.
authors.forename: C
authors.initials: C
authors.lastname: O'Mahony
authors.affiliation: Public Health Laboratory, Public Health England, Bristol, UK.
authors.forename: P
authors.initials: P
authors.lastname: Muir
authors.affiliation: West London Centre for Sexual Health, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK.
authors.forename: C
authors.initials: C
authors.lastname: Evans
authors.affiliation: Whittall Street Clinic, Birmingham Sexual Health, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK keith.radcliffe@uhb.nhs.uk.
authors.forename: K
authors.initials: K
authors.lastname: Radcliffe
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use; D002690:Chlamydia Infections / Q000175:diagnosis / Q000188:drug therapy*; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D019468:Disease Management; D004318:Doxycycline / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D024841:Fluoroquinolones / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D000077266:Moxifloxacin; D009175:Mycoplasma Infections / Q000188:drug therapy*; D045704:Mycoplasma genitalium / Q000302:isolation & purification; D017410:Practice Guidelines as Topic; D006113:United Kingdom; D014526:Urethritis / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D008795:Metronidazole; D017963:Azithromycin; D004318:Doxycycline; D000077266:Moxifloxacin
keywords: Chlamydia trachomatis; Mycoplasma genitalium; NGU; NSU; Non-gonococcal urethritis; chlamydia; sexually transmitted infections; urethritis