title: Inhospital mortality among clinical and surgical inpatients recently diagnosed with venous thromboembolic disease.
abstract: Venous thromboembolism (VTE) is the most common cause of preventable mortality in hospitalized patients, and pulmonary embolism is responsible for 5-10 % of all hospital deaths. To estimate the hospital mortality in hospitalized patients who developed VTE during hospitalization. Prospective cohort of all adult inpatients >17 years admitted to the hospital between August 2006 and August 2013, and follow-up until discharge to measure death. VTE incident cases were captured prospectively from the Institutional Registry of Thromboembolic disease in a tertiary hospital care in Buenos Aires. In hospital global mortality and fatality rate of inpatients with VTE was calculated. The cumulative incidence of VTE was 1.8 % (95 % CI 1.77-1.93 %), representing 1.32 % (95 % CI 1.23-1.41 %) in the subgroup of surgical patients and 2.1 % (95 % CI 1.9-2.2 %) in clinical inpatients. The overall hospital mortality was 2.4 % (95 % CI 2.35-2.53); being 3.95 % (95 % CI 3.78-4.12) in clinical inpatients and 1.15 % (95 % CI 1.06-1.23) in surgical patients. The death in patients who had developed VTE, represented between 4 and 7 % of hospital deaths, and it increases with age in both clinical and surgical patients. In Argentina there are few data of hospital mortality in patients with VTE. This information is useful when assessing the need for resources for prevention, diagnosis and treatment in inpatients.
authors.affiliation: Clinical Research Unit, Hospital Italiano de Buenos Aires, Calle Juan D Perón 4190, Buenos Aires, Argentina, maria.posadas@hospitalitaliano.org.ar.
authors.forename: María Lourdes
authors.initials: ML
authors.lastname: Posadas-Martínez
authors.forename: Fernando Javier
authors.initials: FJ
authors.lastname: Vázquez
authors.forename: María Florencia
authors.initials: MF
authors.lastname: Grande-Ratti
authors.forename: Fernán González Bernaldo
authors.initials: FG
authors.lastname: de Quirós
authors.forename: Diego Hernán
authors.initials: DH
authors.lastname: Giunta
mesh_terms: D000328:Adult; D000367:Age Factors; D001118:Argentina / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D011446:Prospective Studies; D054556:Venous Thromboembolism / Q000209:etiology / Q000401:mortality*