title: Deciphering the tubulin code.
abstract: Enzymes of the tubulin tyrosine ligase-like (TTLL) family posttranslationally modify and thereby mark microtubules by glutamylation, generating specific recognition sites for microtubule-interacting proteins. Garnham et al. report the first structure of a TTLL protein alone and in complex with microtubules, elucidating their mechanism of action.
authors.affiliation: Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, 44227 Dortmund, Germany. Electronic address: stefan.raunser@mpi-dortmund.mpg.de.
authors.forename: Stefan
authors.initials: S
authors.lastname: Raunser
authors.affiliation: Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, 44227 Dortmund, Germany.
authors.forename: Christos
authors.initials: C
authors.lastname: Gatsogiannis
mesh_terms: D000818:Animals; D006801:Humans; D010453:Peptide Synthases / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D010453:Peptide Synthases