title: Prediction of contact mechanics in metal-on-metal Total Hip Replacement for parametrically comprehensive designs and loads.
abstract: Manufacturers and investigators of Total Hip Replacement (THR) bearings require tools to predict the contact mechanics resulting from diverse design and loading parameters. This study provides contact mechanics solutions for metal-on-metal (MoM) bearings that encompass the current design space and could aid pre-clinical design optimization and evaluation. Stochastic finite element (FE) simulation was used to calculate the head-on-cup contact mechanics for five thousand combinations of design and loading parameters. FE results were used to train a Random Forest (RF) surrogate model to rapidly predict the contact patch dimensions, contact area, pressures and plastic deformations for arbitrary designs and loading. In addition to widely observed polar and edge contact, FE results included ring-polar, asymmetric-polar, and transitional categories which have previously received limited attention. Combinations of design and load parameters associated with each contact category were identified. Polar contact pressures were predicted in the range of 0-200 MPa with no permanent deformation. Edge loading (with subluxation) was associated with pressures greater than 500 MPa and induced permanent deformation in 83% of cases. Transitional-edge contact (with little subluxation) was associated with intermediate pressures and permanent deformation in most cases, indicating that, even with ideal anatomical alignment, bearings may face extreme wear challenges. Surrogate models were able to accurately predict contact mechanics 18,000 times faster than FE analyses. The developed surrogate models enable rapid prediction of MoM bearing contact mechanics across the most comprehensive range of loading and designs to date, and may be useful to those performing bearing design optimization or evaluation.
authors.affiliation: Division of Biomedical Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Office of Medical Products and Tobacco, U.S. Food and Drug Administration, Silver Spring, MD, USA. Electronic address: Finn.Donaldson@fda.hhs.gov.
authors.forename: Finn E
authors.initials: FE
authors.lastname: Donaldson
authors.affiliation: Division of Biomedical Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Office of Medical Products and Tobacco, U.S. Food and Drug Administration, Silver Spring, MD, USA.
authors.forename: Edward
authors.initials: E
authors.lastname: Nyman
authors.affiliation: Division of Biomedical Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Office of Medical Products and Tobacco, U.S. Food and Drug Administration, Silver Spring, MD, USA.
authors.forename: James C
authors.initials: JC
authors.lastname: Coburn
mesh_terms: D000465:Algorithms; D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation* / Q000379:methods*; D003198:Computer Simulation; D004548:Elasticity; D020342:Finite Element Analysis; D006622:Hip Prosthesis; D006801:Humans; D008670:Metals; D008962:Models, Theoretical; D011312:Pressure; D011474:Prosthesis Design / Q000379:methods*; D013269:Stochastic Processes; D013314:Stress, Mechanical
chemical_list: D008670:Metals
keywords: Contact mechanics; Finite element analysis; Metal-on-Metal; Surrogate models; Total Hip Arthroplasty; Wear