title: Cancers of major salivary glands.
abstract: Major salivary gland malignancies are a rare but histologically diverse group of entities. Establishing the diagnosis of a malignant salivary neoplasm may be challenging because of the often minimally symptomatic nature of the disease, and limitations of imaging modalities and cytology. Treatment is centered on surgical therapy and adjuvant radiation in selected scenarios. Systemic therapy with chemotherapeutic agents and monoclonal antibodies lacks evidence in support of its routine use.
authors.affiliation: Division of Head and Neck Surgery, University of Nebraska Medical Center, 600 S, 42nd Street, Omaha, NE 68198, USA. Electronic address: aru.panwar@unmc.edu.
authors.forename: Aru
authors.initials: A
authors.lastname: Panwar
authors.affiliation: Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
authors.forename: Jessica A
authors.initials: JA
authors.lastname: Kozel
authors.affiliation: Division of Head and Neck Surgery, Nebraska Methodist Hospital, 8303 Dodge Street, Omaha, NE 68114, USA.
authors.forename: William M
authors.initials: WM
authors.lastname: Lydiatt
mesh_terms: D003131:Combined Modality Therapy; D006801:Humans; D011379:Prognosis; D012468:Salivary Gland Neoplasms / Q000473:pathology* / Q000628:therapy*
keywords: Cancer; Malignancy; Neoplasm; Salivary glands