title: Friend turned foe: a role for bacterial sulfatases in colitis.
abstract: During colitis, gut bacteria and bacterial components can traverse the mucus layer and contact host cells. In this issue of Cell Host & Microbe, Hickey et al. (2015) show that sulfatases of Bacteroides thetaiotaomicron are required for its outer membrane vesicles to transit to underlying host immune cells and cause colitis.
authors.affiliation: Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA.
authors.forename: Maria
authors.initials: M
authors.lastname: Chatzidaki-Livanis
authors.affiliation: Division of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA. Electronic address: lcomstock@rics.bwh.harvard.edu.
authors.forename: Laurie E
authors.initials: LE
authors.lastname: Comstock
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000378:metabolism*; D001439:Bacteroides / Q000378:metabolism*; D003092:Colitis / Q000382:microbiology*; D054884:Host-Pathogen Interactions; D022142:Secretory Vesicles / Q000201:enzymology* / Q000378:metabolism*; D013429:Sulfatases / Q000378:metabolism*
chemical_list: D000942:Antigens, Bacterial; D013429:Sulfatases