title: A radical anti-Markovnikov addition of alkyl nitriles to simple alkenes via selective sp(3) C-H bond functionalization.
abstract: An efficient hydrocyanoalkylation of unactivated alkenes with alkyl nitriles was developed. Through this free-radical-initiated selective activation of the α-C(sp(3))-H bond of acetonitriles, an anti-Markovnikov addition of an α-cyano C-centered radical to olefins has been achieved, which allows a facile and convenient access to functionalized nitriles in large scales.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu 730000, P. R. China. liuzhq@lzu.edu.cn.
authors.forename: Zejiang
authors.initials: Z
authors.lastname: Li
authors.forename: Yingxia
authors.initials: Y
authors.lastname: Xiao
authors.forename: Zhong-Quan
authors.initials: ZQ
authors.lastname: Liu