title: Co-infection of invasive pulmonary aspergillosis and cutaneous Fusarium infection in a patient with pyoderma gangrenosum.
abstract: We report an unusual case of co-infection of invasive pulmonary aspergillosis (IPA) and fusarial skin infection in a patient with classic pyoderma gangrenosum with unknown causes, which were previously controlled with oral prednisolone, cyclosporine. The diagnosis was made on direct microscopy and culture of endobronchial washing, bronchoalveolar lavage and skin lesion biopsy. The treatment failed, and the patient expired 12 days following hospitalization. This report highlights the rarity of coexistence of IPA and a chronic fusarial skin infection and thereby reinforcing the physician's attention toward the possibility of invasive fungal infection in the immunosuppressed patients.
authors.affiliation: Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran ; Department of Laboratory Sciences, School of Paramedical Sciences and Tropical Medicine Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
authors.forename: Nasrin
authors.initials: N
authors.lastname: Amirrajab
authors.affiliation: Department of Pulmonary Diseases, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Aliyali
authors.affiliation: Department of Medical Mycology and Parasitology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Sabah
authors.initials: S
authors.lastname: Mayahi
authors.affiliation: Department of Infectious Disease, North Iranian Tropical and Infectious Disease Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Narges
authors.initials: N
authors.lastname: Najafi
authors.affiliation: Department of Radiology, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Ruhollah
authors.initials: R
authors.lastname: Abdi
authors.affiliation: Skin Research Center, Shahid Beheshti University of Medical Sciences, Shohada-e Tajrish Hospital, Tehran, Iran.
authors.forename: Omid
authors.initials: O
authors.lastname: Nourbakhsh
authors.affiliation: Department of Medical Mycology and Parasitology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran ; Invasive Fungi Research Center, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Tahereh
authors.initials: T
authors.lastname: Shokohi
keywords: Aspergillus; Fusarium; invasive pulmonary aspergillosis; pyoderma gangrenosum