title: Comparison of the diagnostic yield and outcomes between standard 8 h capsule endoscopy and the new 12 h capsule endoscopy for investigating small bowel pathology.
abstract: OBJECTIVE
  To evaluate the completion rate and diagnostic yield of the PillCam SB2-ex in comparison to the PillCam SB2.
  
  
  METHODS
  Two hundred cases using the 8-h PillCam SB2 were retrospectively compared to 200 cases using the 12 h PillCam SB2-ex at a tertiary academic center. Endoscopically placed capsules were excluded from the study. Demographic information, indications for capsule endoscopy, capsule type, study length, completion of exam, clinically significant findings, timestamp of most distant finding, and significant findings beyond 8 h were recorded.
  
  
  RESULTS
  The 8 and 12 h capsule groups were well matched respectively for both age (70.90 ± 14.19 vs 71.93 ± 13.80, P = 0.46) and gender (45.5% vs 48% male, P = 0.69). The most common indications for the procedure in both groups were anemia and obscure gastrointestinal bleeding. PillCam SB2-ex had a significantly higher completion rate than PillCam SB2 (88% vs 79.5%, P = 0.03). Overall, the diagnostic yield was greater for the 8 h capsule (48.5% for SB2 vs 35% for SB2-ex, P = 0.01). In 4/70 (5.7%) of abnormal SB2-ex exams the clinically significant finding was noted in the small bowel beyond the 8 h mark.
  
  
  CONCLUSIONS
  In our study, we found the PillCam SB2-ex to have a significantly increased completion rate, though without any improvement in diagnostic yield compared to the PillCam SB2.
authors.affiliation: Merajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
authors.forename: Merajur
authors.initials: M
authors.lastname: Rahman
authors.affiliation: Merajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
authors.forename: Stuart
authors.initials: S
authors.lastname: Akerman
authors.affiliation: Merajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
authors.forename: Bethany
authors.initials: B
authors.lastname: DeVito
authors.affiliation: Merajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
authors.forename: Larry
authors.initials: L
authors.lastname: Miller
authors.affiliation: Merajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
authors.forename: Meredith
authors.initials: M
authors.lastname: Akerman
authors.affiliation: Merajur Rahman, Bethany DeVito, Larry Miller, Keith Sultan, Division of Gastroenterology, Department of Medicine, North Shore-Long Island Jewish Medical Center, Manhasset, NY 11030, United States.
authors.forename: Keith
authors.initials: K
authors.lastname: Sultan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000209:etiology; D053704:Capsule Endoscopy / Q000295:instrumentation; D019723:Endoscopes; D004867:Equipment Design; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D007410:Intestinal Diseases / Q000150:complications / Q000473:pathology*; D007421:Intestine, Small / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009518:New York; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D013997:Time Factors
keywords: Capsule endoscopy; Obscure gastrointestinal bleeding; PillCam SB2