title: Synthesis, structure and reactivity of [15]-macrodilactones.
abstract: A strategy for utilizing parameters such as the ring size, planar units and the connections between them, and the location of asymmetric centers has been applied to the design and synthesis of a new class of 15-membered macrocycles. The interplay between three planar units in combination with a hinge atom and a stereogenic center, introduces a planar chirality that defines the molecular topology of these [15]-macrodilactones.
authors.affiliation: Department of Chemistry, University of Connecticut, 55 North Eagleville Road, U3060, Storrs, CT 06269, USA. mark.peczuh@uconn.edu.
authors.forename: Debjani
authors.initials: D
authors.lastname: Si
authors.forename: Mark W
authors.initials: MW
authors.lastname: Peczuh
mesh_terms: D060326:Chemistry Techniques, Synthetic; D007783:Lactones / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D007783:Lactones