title: SnapShot: Intrinsic Structural Disorder.
abstract: Many proteins (intrinsically disordered proteins, IDPs) or regions of proteins (intrinsically disordered regions, IDRs) lack a well-defined 3D structure under physiological conditions. Albeit unfolded and highly dynamic, these proteins are not denatured; rather, intrinsic structural disorder is their native, functional state.
authors.affiliation: VIB Structural Biology Research Center (SBRC), Vlaams Instituut voor Biotechnologie, 1050 Brussel, Belgium; Structural Biology Brussels (SBB), Vrije Universiteit Brussel, 1050 Brussel, Belgium.
authors.forename: Mainak
authors.initials: M
authors.lastname: Guharoy
authors.affiliation: VIB Structural Biology Research Center (SBRC), Vlaams Instituut voor Biotechnologie, 1050 Brussel, Belgium; Structural Biology Brussels (SBB), Vrije Universiteit Brussel, 1050 Brussel, Belgium.
authors.forename: Kris
authors.initials: K
authors.lastname: Pauwels
authors.affiliation: VIB Structural Biology Research Center (SBRC), Vlaams Instituut voor Biotechnologie, 1050 Brussel, Belgium; Structural Biology Brussels (SBB), Vrije Universiteit Brussel, 1050 Brussel, Belgium; Institute of Enzymology, Research Centre for Natural Sciences of the Hungarian Academy of Sciences, 1117 Budapest, Hungary.
authors.forename: Peter
authors.initials: P
authors.lastname: Tompa
mesh_terms: D000818:Animals; D006801:Humans; D011487:Protein Conformation; D058767:Protein Unfolding; D011506:Proteins / Q000737:chemistry*
chemical_list: D011506:Proteins