title: [Evaluating the left ventricular diastolic function of diabetes mellitus patients using dual-gate Doppler].
abstract: To evaluate the value of left ventricular diastolic function in type 2 diabetes mellitus (DM) using dual-gate Doppler and relative factors, we included 50 non-obesity and hypertension-free DM patients into the controlled group in the study along with 48 age-and-gender-matched healthy volunteer subjects. The peak early diastolic velocity (E), peak later diastolic velocity (A), deceleration time (DT), anterior mitral annulus diastolic peak velocity (e') , isovolumic relaxation time (IVRT), E/A, E/e', Tei index and T(E-e), were measured with dual-gate Doppler. 20 subjects were randomly selected for repetitive analysis. Study showed statistical difference in E/A, DT, e', E/e', IVRT, Tei index and T(E-e), between the two groups (P < 0.05). Linear regression analysis showed positive correlation between T(E-e), and IVRT, course of DM patients and T(E-e), (Beta = 0.295, P = 0.020), and HbA1c control level and T(E-e), (Beta = 0.399, P = 0.010). Repeated analysis showed good reproducibility for both within and between groups. Dual-gate Doppler has clinical value in evaluating left ventricular diastolic function in type 2 diabetes mellitus patients. The course of type 2 diabetes mellitus patients and HbA(1C) control level were both closely related with left ventricular diastolic function.
authors.forename: Jiani
authors.initials: J
authors.lastname: Liu
authors.forename: Liping
authors.initials: L
authors.lastname: Chen
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Zhang
authors.forename: Yanwen
authors.initials: Y
authors.lastname: Shang
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.forename: Hong
authors.initials: H
authors.lastname: Tang
mesh_terms: D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D003971:Diastole; D015150:Echocardiography, Doppler; D006801:Humans; D006973:Hypertension; D008943:Mitral Valve; D012044:Regression Analysis; D015203:Reproducibility of Results; D018487:Ventricular Dysfunction, Left; D016277:Ventricular Function, Left