title: Babesiosis.
abstract: Babesiosis is caused by intraerythrocytic protozoan parasites that are transmitted by ticks, or less commonly through blood transfusion or transplacentally. Human babesiosis was first recognized in a splenectomized patient in Europe but most cases have been reported from the northeastern and upper midwestern United States in people with an intact spleen and no history of immune impairment. Cases are reported in Asia, Africa, Australia, Europe, and South America. Babesiosis shares many clinical features with malaria and can be fatal, particularly in the elderly and the immunocompromised.
authors.affiliation: Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street Box #041, Boston, MA 02111, USA.
authors.forename: Edouard G
authors.initials: EG
authors.lastname: Vannier
authors.affiliation: Department of Ecology, Evolution, and Environmental Biology, Columbia University, 1200 Amsterdam Avenue, New York, NY 10027, USA.
authors.forename: Maria A
authors.initials: MA
authors.lastname: Diuk-Wasser
authors.affiliation: Department of Internal Medicine, Yale School of Medicine, 15 York Street, New Haven, CT 06520, USA.
authors.forename: Choukri
authors.initials: C
authors.lastname: Ben Mamoun
authors.affiliation: Department of Epidemiology of Microbial Diseases, Yale School of Public Health, 60 College Street, New Haven, CT 06520, USA; Departments of Internal Medicine and Pediatrics, Yale School of Medicine, 15 York Street, New Haven, CT 06520, USA. Electronic address: peter.krause@yale.edu.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Krause
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001403:Babesia / Q000302:isolation & purification*; D001404:Babesiosis / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission; D016054:DNA, Protozoan / Q000032:analysis; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D004912:Erythrocytes / Q000469:parasitology; D006801:Humans; D016133:Polymerase Chain Reaction
chemical_list: D000900:Anti-Bacterial Agents; D016054:DNA, Protozoan; D004791:Enzyme Inhibitors
keywords: Apicomplexa; Babesia microti; Babesiosis; Erythrocyte; Protozoan; Tick; Transfusion