title: Localized malignant pleural mesothelioma with renal metastasis.
abstract: Localized malignant pleural mesothelioma (LMM) is a rare subset of malignant pleural mesothelioma. Its epidemiology, biology, natural history and optimal treatment are poorly understood. We report a case of LMM treated aggressively with complete surgical resection and adjuvant radiotherapy, but subsequently complicated by local chest wall recurrence and solitary metastasis to the kidney. This case is examined in the context of a small number of cases of LMM in the literature to emphasize the existence of this rare disease entity, their unusual biological behaviour and the need for further tumour molecular and genomic research.
authors.affiliation: Department of Medical Oncology , Royal North Shore Hospital , Sydney, NSW , Australia.
authors.forename: Sarah Jane
authors.initials: SJ
authors.lastname: Zardawi
authors.affiliation: Department of Medicine, Division of Solid Tumor Oncology, Thoracic Oncology Service , Memorial Sloan Kettering Cancer Center , New York, NY , USA ; Sydney Medical School , University of Sydney , Sydney, NSW , Australia.
authors.forename: Bob T
authors.initials: BT
authors.lastname: Li
authors.affiliation: Department of Medicine, Division of Solid Tumor Oncology, Thoracic Oncology Service , Memorial Sloan Kettering Cancer Center , New York, NY , USA ; Weill Cornell Medical College , New York, NY , USA.
authors.forename: Marjorie G
authors.initials: MG
authors.lastname: Zauderer
authors.affiliation: Department of Anatomical Pathology , Royal North Shore Hospital , Sydney, NSW , Australia.
authors.forename: Jennifer W
authors.initials: JW
authors.lastname: Wang
authors.affiliation: Sydney Medical School , University of Sydney , Sydney, NSW , Australia ; Department of Anatomical Pathology , Royal North Shore Hospital , Sydney, NSW , Australia.
authors.forename: Bryn B
authors.initials: BB
authors.lastname: Atmore
authors.affiliation: Department of Medical Oncology , Royal North Shore Hospital , Sydney, NSW , Australia.
authors.forename: Tristan A
authors.initials: TA
authors.lastname: Barnes
authors.affiliation: Department of Medical Oncology , Royal North Shore Hospital , Sydney, NSW , Australia ; Sydney Medical School , University of Sydney , Sydney, NSW , Australia.
authors.forename: Nick
authors.initials: N
authors.lastname: Pavlakis
authors.affiliation: Department of Cardiothoracic Surgery , Royal North Shore Hospital , Sydney, NSW , Australia.
authors.forename: Manu N
authors.initials: MN
authors.lastname: Mathur
authors.affiliation: Department of Medical Oncology , Royal North Shore Hospital , Sydney, NSW , Australia ; Sydney Medical School , University of Sydney , Sydney, NSW , Australia.
authors.forename: Stephen
authors.initials: S
authors.lastname: Clarke