title: The Relationship between Positive Peritoneal Cytology and the Prognosis of Patients with Uterine Cervical Cancer.
abstract: OBJECTIVE
  We investigated the association of positive peritoneal cytology with prognosis in uterine cervical cancer.
  
  
  METHODS
  We reviewed the medical records and cytologic materials of 225 Japanese patients with FIGO IB1-IVB uterine cervical cancer who had undergone surgery at our University Hospital between 1993 and 2012. Univariate and multivariate regression analyses were performed for statistical analysis.
  
  
  RESULTS
  Positive peritoneal cytology was noted in 6 of 225 patients (2.7%). Positive peritoneal cytology was found in 4 of 149 patients (2.6%) with squamous cell carcinoma (SCC) and in 2 of 70 patients (2.8%) with non-SCC (p = 0.9434). The 5-year survival rate of patients with positive peritoneal cytology was significantly lower than that of patients with negative cytology (50 vs. 84.6%, p = 0.001) in univariate survival analysis. However, peritoneal cytology no longer remained significant in multivariate analysis.
  
  
  CONCLUSIONS
  Although we conclude that positive peritoneal cytology in uterine cervical cancer is a poor prognostic factor, further investigation and multi-institutional studies are necessary.
authors.affiliation: Department of Obstetrics and Gynecology, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Kurita
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Matsuura
authors.forename: Chiho
authors.initials: C
authors.lastname: Koi
authors.forename: Seiji
authors.initials: S
authors.lastname: Kagami
authors.forename: Toshinori
authors.initials: T
authors.lastname: Kawagoe
authors.forename: Toru
authors.initials: T
authors.lastname: Hachisuga
mesh_terms: D002277:Carcinoma / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007564:Japan; D053208:Kaplan-Meier Estimate; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D016017:Odds Ratio; D010529:Peritoneal Cavity / Q000473:pathology*; D011237:Predictive Value of Tests; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery