title: Chemotherapy treatment of a pregnant woman with progressive gastric cancer.
abstract: We herein describe a rare case of gastric cancer that was treated with chemotherapy during pregnancy. A woman in her thirty's at 23 weeks of gestation was admitted to the hospital with epigastralgia and left cervical lymph node swelling. She had been previously diagnosed with metastatic adenocarcinoma at another hospital. Findings from a CT scan and esophagogastroduodenoscopy revealed progressive gastric cancer, and the pathology indicated poorly differentiated adenocarcinoma. Chemotherapy was administered at 24 weeks of gestation, without the development of severe toxicity. At 32 weeks of gestation, a healthy baby girl (birth weight 1,442 g, Apgar score 7/8) was delivered by caesarean section. The child continued to show no abnormalities at 12 months after delivery.
authors.affiliation: Department of Gastroenterology, Gifu Prefectual Tajimi Hospital, Japan.
authors.forename: Hirotada
authors.initials: H
authors.lastname: Nishie
authors.forename: Takashi
authors.initials: T
authors.lastname: Mizushima
authors.forename: Yuta
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Shigeki
authors.initials: S
authors.lastname: Fukusada
authors.forename: Tadahisa
authors.initials: T
authors.lastname: Inoue
authors.forename: Kenta
authors.initials: K
authors.lastname: Kachi
authors.forename: Takanori
authors.initials: T
authors.lastname: Ozeki
authors.forename: Kaiki
authors.initials: K
authors.lastname: Anbe
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Iwasaki
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Okumura
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Sano
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002585:Cesarean Section / Q000379:methods*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D055756:Meningeal Carcinomatosis / Q000209:etiology; D017239:Paclitaxel / Q000008:administration & dosage; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy* / Q000473:pathology; D011256:Pregnancy Outcome; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D017239:Paclitaxel