title: [Cycloferon therapy of chronic gastroduodenitis in children].
abstract: The efficiency of immunomodulating therapy with cycloferon in children aged from 10 to 16 years with verified chronic gastroduodenitis was estimated. It was shown that the cycloferon treatment provided reliable increase of T- and B-cellular populations in mucous membranes of the stomach and duodenum, normalization of the number of CD8-lymphocytes, higher titers of IgG antibodies to herpes viruses 1 and 2. It also promoted reduction of inflammation in the mucous membranes along with reduction of the disease clinical signs.
authors.forename: S Yu
authors.initials: SY
authors.lastname: Yermak
authors.forename: S A
authors.initials: SA
authors.lastname: Lialikov
authors.forename: M G
authors.initials: MG
authors.lastname: Zubritsky
authors.forename: O N
authors.initials: ON
authors.lastname: Borodavko
mesh_terms: D000166:Acridines / Q000627:therapeutic use*; D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood*; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology / Q000821:virology; D018414:CD8-Positive T-Lymphocytes / Q000187:drug effects / Q000276:immunology / Q000821:virology; D002648:Child; D002908:Chronic Disease; D004382:Duodenitis / Q000150:complications / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D004386:Duodenum / Q000187:drug effects / Q000276:immunology / Q000821:virology; D005260:Female; D005756:Gastritis / Q000150:complications / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D006561:Herpes Simplex / Q000150:complications / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D018259:Herpesvirus 1, Human / Q000187:drug effects / Q000276:immunology; D018258:Herpesvirus 2, Human / Q000187:drug effects / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007369:Interferon Inducers / Q000627:therapeutic use*; D018655:Lymphocyte Count; D008297:Male; D013270:Stomach / Q000187:drug effects / Q000276:immunology / Q000821:virology
chemical_list: D000166:Acridines; D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007369:Interferon Inducers; C026430:10-carboxymethyl-9-acridanone