title: [Inflammatory pseudotumour of the liver. Importance of intra-operative histopathology].
abstract: BACKGROUND
  Inflammatory pseudotumour is a rare entity, considered benign, and characterised by inflammatory cell mesenchymal proliferation.
  
  
  METHODS
  The case is presented 70 year-old man with fever of unknown origin syndrome. He was diagnosed with liver abscesses (one segment IV, adjacent to gallbladder fundus and segment VI), who progressed slowly after antibiotic treatment. In the absence of a diagnosis, although fine needle puncture-aspiration and different imaging tests were performed, elective surgery was decided. The intra-operative histopathology reported the existence of an inflammatory pseudotumour.
  
  
  CONCLUSIONS
  Inflammatory pseudotumours are clinically classified into different types according to their aetiology, varying therapeutic management based on the same. It is very difficult to diagnose because of the absence of symptoms, blood disorders, or specific radiological findings. Definitive diagnosis often requires histopathological confirmation, in most cases by percutaneous liver puncture, but sometimes exploratory laparotomy or even performing a hepatectomy for confirmation is necessary. The natural history of inflammatory pseudotumour is its regression; thus conservative management may be used through regular checks until resolution, or can be treated with antibiotics, anti-inflammatories and even corticosteroids. Surgical resection is indicated for persistent unresolved systemic symptoms despite medical treatment, in those situations where growth is evident, with or without symptoms, when involving the hepatic hilum, and finally, in case where the possibility of malignancy cannot be ruled out.
authors.affiliation: Servicio de Cirugía General y del Aparato Digestivo, Hospital de Don Benito-Villanueva, Don Benito, Badajoz, España. Electronic address: franonieva9@gmail.com.
authors.forename: Francisco Gabriel
authors.initials: FG
authors.lastname: Onieva-González
authors.affiliation: Servicio de Cirugía Hepatobiliopancreática y de Trasplante Hepático, Hospital Infanta Cristina, Badajoz, España.
authors.forename: Francisco
authors.initials: F
authors.lastname: Galeano-Díaz
authors.affiliation: Servicio de Cirugía Hepatobiliopancreática y de Trasplante Hepático, Hospital Infanta Cristina, Badajoz, España.
authors.forename: María José
authors.initials: MJ
authors.lastname: Matito-Díaz
authors.affiliation: Servicio de Cirugía Hepatobiliopancreática y de Trasplante Hepático, Hospital Infanta Cristina, Badajoz, España.
authors.forename: Diego
authors.initials: D
authors.lastname: López-Guerra
authors.affiliation: Servicio de Cirugía Hepatobiliopancreática y de Trasplante Hepático, Hospital Infanta Cristina, Badajoz, España.
authors.forename: Juana
authors.initials: J
authors.lastname: Fernández-Pérez
authors.affiliation: Servicio de Cirugía Hepatobiliopancreática y de Trasplante Hepático, Hospital Infanta Cristina, Badajoz, España.
authors.forename: Gerardo
authors.initials: G
authors.lastname: Blanco-Fernández
mesh_terms: D000368:Aged; D006104:Granuloma, Plasma Cell / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007430:Intraoperative Care; D008107:Liver Diseases / Q000473:pathology* / Q000601:surgery; D008297:Male
keywords: Fever of unknown origin; Fiebre de origen desconocido; Hepatic neoplasms; Inflammatory Pseudotumour; Neoplasias hepáticas; Pseudotumor inflamatorio