title: The effect of graft strength on knee laxity and graft in-situ forces after posterior cruciate ligament reconstruction.
abstract: Surgical reconstruction is generally recommended for posterior cruciate ligament (PCL) injuries; however, the use of grafts is still a controversial problem. In this study, a three-dimensional finite element model of the human tibiofemoral joint with articular cartilage layers, menisci, and four main ligaments was constructed to investigate the effects of graft strengths on knee kinematics and in-situ forces of PCL grafts. Nine different graft strengths with stiffness ranging from 0% (PCL rupture) to 200%, in increments of 25%, of an intact PCL's strength were used to simulate the PCL reconstruction. A 100 N posterior tibial drawer load was applied to the knee joint at full extension. Results revealed that the maximum posterior translation of the PCL rupture model (0% stiffness) was 6.77 mm in the medial compartment, which resulted in tibial internal rotation of about 3.01°. After PCL reconstruction with any graft strength, the laxity of the medial tibial compartment was noticeably improved. Tibial translation and rotation were similar to the intact knee after PCL reconstruction with graft strengths ranging from 75% to 125% of an intact PCL. When the graft's strength surpassed 150%, the medial tibia moved forward and external tibial rotation greatly increased. The in-situ forces generated in the PCL grafts ranged from 13.15 N to 75.82 N, depending on the stiffness. In conclusion, the strength of PCL grafts have has a noticeable effect on anterior-posterior translation of the medial tibial compartment and its in-situ force. Similar kinematic response may happen in the models when the PCL graft's strength lies between 75% and 125% of an intact PCL.
authors.affiliation: Orthopaedic Device Research Center, National Yang-Ming University, Taipei, Taiwan.
authors.forename: Yu-Shu
authors.initials: YS
authors.lastname: Lai
authors.affiliation: Orthopaedic Device Research Center, National Yang-Ming University, Taipei, Taiwan.
authors.forename: Wen-Chuan
authors.initials: WC
authors.lastname: Chen
authors.affiliation: Department of Medical Research, Mackay Memorial Hospital, New Taipei City, Taiwan.
authors.forename: Chang-Hung
authors.initials: CH
authors.lastname: Huang
authors.affiliation: Department of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan.
authors.forename: Cheng-Kung
authors.initials: CK
authors.lastname: Cheng
authors.affiliation: Department of Orthopaedics, Cardinal Tien Hospital, New Taipei City, Taiwan.
authors.forename: Kam-Kong
authors.initials: KK
authors.lastname: Chan
authors.affiliation: Department of Orthopedics, Mackay Memorial Hospital, Taipei, Taiwan; Mackay Medical College, New Taipei City, Taiwan.
authors.forename: Ting-Kuo
authors.initials: TK
authors.lastname: Chang
mesh_terms: D001178:Arthroplasty / Q000379:methods*; D001696:Biomechanical Phenomena / Q000502:physiology; D002358:Cartilage, Articular / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007593:Joint Instability / Q000503:physiopathology / Q000601:surgery*; D007719:Knee Joint / Q000503:physiopathology / Q000601:surgery*; D008953:Models, Anatomic; D016119:Posterior Cruciate Ligament / Q000503:physiopathology / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D016474:Weight-Bearing / Q000502:physiology