title: Increasing trends in kidney cancer over the last 2 decades in Saudi Arabia.
abstract: OBJECTIVE
  To examine the trends of kidney cancer over the last 2 decades in a subset of a Saudi Arabian population.
  
  
  METHODS
  We conducted a retrospective study in a tertiary care center including all adult patients with primary kidney cancer who presented and were managed between 1990 and 2010. The time period was split into 4 quartiles, and variables tested and compared using chi-square, T-test, and Kaplan-Meier curves for survival.
  
  
  RESULTS
  The total was 215 patients with a mean age of 57.8 years. There was an increase in the number of kidney cancer cases over the last 2 decades. There was no significant difference in the mode of presentation or stage distribution between quartiles. A significant change was observed in the management towards minimally invasive and nephron-sparing surgeries (p less than 0.001). There was no change in recurrence-free and disease-specific survival over the last 20 years.
  
  
  CONCLUSIONS
  There have been an increasing number of kidney cancer patients over the last 2 decades with no observed migration towards more incidental and low stage tumors as compared with developed countries.
authors.affiliation: Division of Urology, Department of Surgery, King Abdulaziz Medical City, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia. E-mail. sultan.alkhateeb@gmail.com.
authors.forename: Sultan S
authors.initials: SS
authors.lastname: Alkhateeb
authors.forename: Jawaher M
authors.initials: JM
authors.lastname: Alkhateeb
authors.forename: Eman A
authors.initials: EA
authors.lastname: Alrashidi
mesh_terms: D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D007680:Kidney Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000639:trends; D060787:Neoplasm Grading; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D009392:Nephrectomy / Q000639:trends; D009399:Nephrons; D059351:Organ Sparing Treatments / Q000639:trends; D011158:Population Growth; D012189:Retrospective Studies; D012529:Saudi Arabia / Q000453:epidemiology; D015996:Survival Rate; D062606:Tertiary Care Centers