title: Cirrhotic liver: What's that nodule? The LI-RADS approach.
abstract: The Liver Imaging Reporting and Data System (LI-RADS) is an American College of Radiology (ACR)-endorsed diagnostic system of standardized terminology, interpretation, and reporting for imaging examinations of the liver in patients at high risk for hepatocellular carcinoma (HCC). LI-RADS assigns a category to observations in the liver indicating the likelihood of benignity or HCC. LI-RADS categories include LR-1: Definitely Benign, LR-2: Probably Benign, LR-3: Intermediate Probability for HCC, LR-4: Probably HCC, LR-5: Definite HCC, LR-5V: Definite HCC with Tumor in Vein, LR-Treated: Treated HCC, LR-M Probable Malignancy, not specific for HCC. This article reviews the types of nodules seen in the cirrhotic liver, examines core LI-RADS concepts and definitions, and utilizes the LI-RADS v2014 algorithm to categorize representative observations depicted at magnetic resonance imaging in a case-based approach.
authors.affiliation: UCSD, Liver Imaging Group, Department of Radiology, San Diego, California, USA.
authors.forename: Amol
authors.initials: A
authors.lastname: Shah
authors.affiliation: UCSD, Liver Imaging Group, Department of Radiology, San Diego, California, USA.|Centre Hospitalier de L'Universite De Montreal, Department of Radiology Montreal, Quebec, Canada.
authors.forename: An
authors.initials: A
authors.lastname: Tang
authors.affiliation: UCSD, Liver Imaging Group, Department of Radiology, San Diego, California, USA.
authors.forename: Cynthia
authors.initials: C
authors.lastname: Santillan
authors.affiliation: UCSD, Liver Imaging Group, Department of Radiology, San Diego, California, USA.
authors.forename: Claude
authors.initials: C
authors.lastname: Sirlin
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000175:diagnosis*; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D008113:Liver Neoplasms / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D011873:Radiology Information Systems; D014057:Tomography, X-Ray Computed
keywords: ACR; HCC; LI-RADS