title: COMMENTARY. Pre-emptive Nutrition: Refining the Targets of Drugs Targeted to Colorectal Cancer.
abstract: It is suggested that our current understanding of the role of nutrients in maintaining genomic stability might be strategically employed alongside current chemotherapy, in order to prevent the emergence of drug resistant tumors and optimize medicinal chemistry approaches.
authors.affiliation: Auckland Cancer Society Research Centre, Faculty of Medical & Health Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand. l.ferguson@auckland.ac.nz.
authors.forename: Lynnette R
authors.initials: LR
authors.lastname: Ferguson
authors.forename: William A
authors.initials: WA
authors.lastname: Denny
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000235:genetics* / Q000382:microbiology / Q000517:prevention & control; D004035:Diet Therapy / Q000379:methods; D019008:Drug Resistance, Neoplasm / Q000187:drug effects / Q000235:genetics; D000069196:Gastrointestinal Microbiome; D042822:Genomic Instability / Q000187:drug effects*; D006801:Humans; D064307:Microbiota / Q000187:drug effects / Q000235:genetics; D054647:Nutrigenomics / Q000379:methods; D009747:Nutritional Physiological Phenomena / Q000235:genetics; D014807:Vitamin D / Q000494:pharmacology / Q000502:physiology
chemical_list: D000970:Antineoplastic Agents; D014807:Vitamin D