title: [The possibility of using PlasmaDeepDive™ MRM panel in clinical diagnostics].
abstract: Concentrations of 46 proteins have been determined in human blood plasma using PlasmaDeepDive™ MRM Panel ("Biognosys AG", Switzerland). 18 of them were included into the group of proteins with higher concentrations, also identified by the shotgun proteomic analysis. Based on literature data it is concluded that the PlasmaDeepDive™ MRM Panel is applicable for studies of human plasma samples for potential biomarkers of various nervous system disorders.
authors.affiliation: Institute of Biomedical Chemistry, Moscow, Russia.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Miroshnichenko
authors.affiliation: Institute of Biomedical Chemistry, Moscow, Russia.
authors.forename: N A
authors.initials: NA
authors.lastname: Petushkova
authors.affiliation: Institute of Biomedical Chemistry, Moscow, Russia.
authors.forename: N E
authors.initials: NE
authors.lastname: Moskaleva
authors.affiliation: Burdenko Institute of Neurosurgery, Moscow, Russia.
authors.forename: N B
authors.initials: NB
authors.lastname: Teryaeva
authors.affiliation: Institute of Biomedical Chemistry, Moscow, Russia.
authors.forename: V G
authors.initials: VG
authors.lastname: Zgoda
authors.affiliation: Institute of Biomedical Chemistry, Moscow, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Ilgisonis
authors.affiliation: Burdenko Institute of Neurosurgery, Moscow, Russia.
authors.forename: A Yu
authors.initials: AY
authors.lastname: Belyaev
mesh_terms: D001798:Blood Proteins / Q000032:analysis*; D006801:Humans; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D040901:Proteomics / Q000379:methods*; D053719:Tandem Mass Spectrometry / Q000379:methods
chemical_list: D001798:Blood Proteins
keywords: biomarkers; mass spectrometry; pathology of the central nervous system; peptide; protein panel; quantitative proteomics