title: [Epidemiological and clinical features of norovirus infection among diarrhea patients from the enteric clinics in Beijing, 2013-2014].
abstract: OBJECTIVE
  To investigate the epidemiological and clinical characteristics of norovirus infection on diarrhea patients from the enteric clinics in Beijing.
  
  
  METHODS
  From April 2013 to March 2014, 1 892 fecal specimens and related epidemiological information were collected among diarrhea patients visiting the enteric clinics in Beijing. Norovirus was detected by real time RT-PCR, and data was analyzed under the descriptive epidemiological method.
  
  
  RESULTS
  A total of 269 positive cases were found among 1 892 diarrhea patients, with a positive rate as 14.2%. Norovirus caused diarrhea mainly occurred in seasons with lower temperature. Higher positive rates of norovirus were found in northwest mountainous area. Norovirus diarrhea was more commonly seen in children between 6 month and 5 years old, with differences between the two groups statistically significant (P = 0.006). Compared with other occupation, a higher infection rate was identified in children, with differences between the two groups statistically significant (P = 0.025). Nausea and vomiting appeared more common in diarrhea patients with norovirus infection, with differences between the two groups statistically significant (P < 0.05).
  
  
  CONCLUSIONS
  Norovirus was an important pathogen which causing diarrhea in patients visiting the enteric clinics in Beijing. The virus was seen more in patients aged between 6 months and 5 years old. Nausea and vomiting were the common symptoms seen in patients with norovirus diarrhea.
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China; Beijing Center for Disease Control and Prevention.
authors.forename: Baiwei
authors.initials: B
authors.lastname: Liu
authors.affiliation: Beijing Center for Disease Control and Prevention.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Gao
authors.affiliation: Beijing Center for Disease Control and Prevention.
authors.forename: Quanyi
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Beijing Center for Disease Control and Prevention.
authors.forename: Xiong
authors.initials: X
authors.lastname: He
authors.affiliation: Beijing Center for Disease Control and Prevention.
authors.forename: Lei
authors.initials: L
authors.lastname: Jia
authors.affiliation: Beijing Center for Disease Control and Prevention.
authors.forename: Xitai
authors.initials: X
authors.lastname: Li
authors.affiliation: Beijing Center for Disease Control and Prevention.
authors.forename: Haikun
authors.initials: H
authors.lastname: Qian
authors.affiliation: Beijing Center for Disease Control and Prevention.
authors.forename: Da
authors.initials: D
authors.lastname: Huo
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing 100191, China; Email: caoweihua60@163.com.
authors.forename: Weihua
authors.initials: W
authors.lastname: Cao
mesh_terms: D017250:Caliciviridae Infections / Q000150:complications* / Q000453:epidemiology*; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003967:Diarrhea / Q000821:virology*; D006801:Humans; D007223:Infant; D009325:Nausea / Q000821:virology; D029322:Norovirus / Q000302:isolation & purification*; D060888:Real-Time Polymerase Chain Reaction; D012621:Seasons; D014839:Vomiting / Q000821:virology