title: Implications of Green Tea and Its Constituents in the Prevention of Cancer via the Modulation of Cell Signalling Pathway.
abstract: Green tea is commonly used as a beverage worldwide, especially in China, Japan, Morocco, and Saudi Arabia. Green tea and its constituents have been considered very effective in the prevention and treatment of various diseases. It contains a variety of catechins, which show a pivotal role in the modulation of biological activities and also act as chemopreventive agents. Earlier studies have confirmed that green tea and its chief constituent epigallocatechin gallate (EGCG) have a potential role in the management of cancer through the modulation of cell signaling pathways. In this review, we focused on the beneficial effects of green tea and its constituents in the cancer prevention and treatment and its impact on modulation of molecular pathways.
authors.affiliation: Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah 6699, Saudi Arabia.
authors.forename: Arshad H
authors.initials: AH
authors.lastname: Rahmani
authors.affiliation: Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah 6699, Saudi Arabia.
authors.forename: Fahad M
authors.initials: FM
authors.lastname: Al Shabrmi
authors.affiliation: Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah 6699, Saudi Arabia.
authors.forename: Khaled S
authors.initials: KS
authors.lastname: Allemailem
authors.affiliation: Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah 6699, Saudi Arabia ; Department of Pathology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt.
authors.forename: Salah M
authors.initials: SM
authors.lastname: Aly
authors.affiliation: Department of Basic Health Science, College of Applied Medical Sciences, Qassim University, Buraidah 6699, Saudi Arabia.
authors.forename: Masood A
authors.initials: MA
authors.lastname: Khan
mesh_terms: D017209:Apoptosis / Q000187:drug effects; D002392:Catechin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism / Q000627:therapeutic use; D002681:China; D006801:Humans; D007564:Japan; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000517:prevention & control*; D012529:Saudi Arabia; D015398:Signal Transduction / Q000187:drug effects; D013662:Tea / Q000737:chemistry
chemical_list: D013662:Tea; D002392:Catechin; C045651:epigallocatechin gallate