title: INTRASURGICAL MICROSCOPE-INTEGRATED SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY-ASSISTED MEMBRANE PEELING.
abstract: OBJECTIVE
  To evaluate microscope-integrated intrasurgical spectral domain optical coherence tomography during macular surgery in a prospective monocenter study.
  
  
  METHODS
  Before pars plana vitrectomy and before, during, and after membrane peeling, 512 × 128 macular cube scans were performed using a Carl Zeiss Meditec Cirrus high-definition OCT system adapted to the optical pathway of a Zeiss OPMI VISU 200 surgical microscope and compared with retinal staining.
  
  
  RESULTS
  The study included 51 patients with epiretinal membranes, with 8 of those having additional lamellar macular holes, 11 patients with vitreomacular traction, and 8 patients with full-thickness macular holes. Intraoperative spectral domain optical coherence tomography allowed performing membrane peeling without using retinal dyes in 40% of cases (28 of 70 patients). No residual membranes were found in 94.3% of patients (66 of 70 patients) in intrasurgical spectral domain optical coherence tomography and subsequent (re)staining. In patients with vitreomacular traction, intrasurgical spectral domain optical coherence tomography scans facilitated decisions on the need for an intraocular tamponade after membrane peeling.
  
  
  CONCLUSIONS
  Intraoperative spectral domain optical coherence tomography was comparable with retinal dyes in confirming success after membrane peeling. However, the visualization of flat membranes was better after staining.
authors.affiliation: Ludwig Boltzmann Institute for Retinology and Biomicroscopic Lasersurgery, Department of Ophthalmology, Rudolf Foundation Clinic, Teaching Hospital of the Medical University, Vienna, Austria.
authors.forename: Christiane I
authors.initials: CI
authors.lastname: Falkner-Radler
authors.forename: Carl
authors.initials: C
authors.lastname: Glittenberg
authors.forename: Max
authors.initials: M
authors.lastname: Gabriel
authors.forename: Susanne
authors.initials: S
authors.lastname: Binder
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004396:Coloring Agents / Q000008:administration & dosage; D065187:Controlled Before-After Studies; D058450:Endotamponade; D019773:Epiretinal Membrane / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008853:Microscopy / Q000295:instrumentation*; D008875:Middle Aged; D011446:Prospective Studies; D012163:Retinal Detachment / Q000503:physiopathology / Q000601:surgery*; D012167:Retinal Perforations / Q000503:physiopathology / Q000601:surgery*; D025321:Surgery, Computer-Assisted; D041623:Tomography, Optical Coherence / Q000295:instrumentation*; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy
chemical_list: D004396:Coloring Agents