title: A Sleeping Beauty Screen Highlights Cancer Drivers in Osteosarcoma.
abstract: Osteosarcoma driver genes are enriched in the ERBB, PI3K-AKT-mTOR, MAPK, and axon guidance pathways.
mesh_terms: D000818:Animals; D001859:Bone Neoplasms / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D006801:Humans; D051379:Mice; D016254:Mutagenesis, Insertional; D012516:Osteosarcoma / Q000235:genetics*; D015398:Signal Transduction; D019895:Transposases / Q000235:genetics*; D016159:Tumor Suppressor Protein p53 / Q000235:genetics*
chemical_list: D016159:Tumor Suppressor Protein p53; D019895:Transposases; C494471:sleeping beauty transposase, human