title: Tripartite comparison of single-incision and conventional laparoscopy in cholecystectomy: A multicenter trial.
abstract: OBJECTIVE
  To compare the characteristics of two single-incision methods, and conventional laparoscopy in cholecystectomy, and demonstrate the safety and feasibility.
  
  
  METHODS
  Three hundred patients with gallstones or gallbladder polyps were admitted to two clinical centers from January 2013 to January 2014 and were randomized into three groups of 100: single-incision three-device group, X-Cone group, and conventional group. The operative time, intraoperative blood loss, complications, postoperative pain, cosmetic score, length of hospitalization, and hospital costs were compared, with a follow-up duration of 1 mo.
  
  
  RESULTS
  A total of 142 males (47%) and 158 females (53%) were enrolled in this study. The population characteristics of these three groups is no significant differences exist in terms of age, sex, body mass index and American Society of Anesthesiology (P > 0.05). In results, there were no significant differences in blood loss, length of hospitalization, postoperative complications.The operative time in X-Cone group was significantly longer than other groups.There were significant differences in postoperative pain scores and cosmetic scores at diffent times after surgery (P < 0.05).
  
  
  CONCLUSIONS
  This study shows that this two single-incision methods are safe and feasible. Both methods are superior to the conventional procedure in cosmetic and pain scores.
authors.affiliation: Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
authors.forename: Guo-Lin
authors.initials: GL
authors.lastname: He
authors.affiliation: Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
authors.forename: Ze-Sheng
authors.initials: ZS
authors.lastname: Jiang
authors.affiliation: Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Cheng
authors.affiliation: Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
authors.forename: Qing-Bo
authors.initials: QB
authors.lastname: Lai
authors.affiliation: Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
authors.forename: Chen-Jie
authors.initials: CJ
authors.lastname: Zhou
authors.affiliation: Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Liu
authors.affiliation: Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
authors.forename: Ming-Xin
authors.initials: MX
authors.lastname: Pan
authors.affiliation: Guo-Lin He, Ze-Sheng Jiang, Yuan Cheng, Chen-Jie Zhou, Hai-Yan Liu, Yi Gao, Ming-Xin Pan, Department of Hepatobiliary Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
authors.forename: Zhi-Xiang
authors.initials: ZX
authors.lastname: Jian
keywords: Cholecystectomy; Laparoscopic surgery; Single-incision laparoscopic cholecystectomy