title: The dynamic deformation of a layered viscoelastic medium under surface excitation.
abstract: In this study the dynamic behavior of a layered viscoelastic medium in response to the harmonic and impulsive acoustic radiation force applied to its surface was investigated both theoretically and experimentally. An analytical solution for a layered viscoelastic compressible medium in frequency and time domains was obtained using the Hankel transform. A special incompressible case was considered to model soft biological tissues. To verify our theoretical model, experiments were performed using tissue-like gel-based phantoms with varying mechanical properties. A 3.5 MHz single-element focused ultrasound transducer was used to apply the radiation force at the surface of the phantoms. A phase-sensitive optical coherence tomography system was used to track the displacements of the phantom surface. Theoretically predicted displacements were compared with experimental measurements. The role of the depth dependence of the elastic properties of a medium in its response to an acoustic pulse at the surface was studied. It was shown that the low-frequency vibrations at the surface are more sensitive to the deep layers than high-frequency ones. Therefore, the proposed model in combination with spectral analysis can be used to evaluate depth-dependent distribution of the mechanical properties based on the measurements of the surface deformation.
authors.affiliation: Biomedical Engineering, University of Texas at Austin, Austin, TX 78731, USA.
authors.forename: Salavat R
authors.initials: SR
authors.lastname: Aglyamov
authors.forename: Shang
authors.initials: S
authors.lastname: Wang
authors.forename: Andrei B
authors.initials: AB
authors.lastname: Karpiouk
authors.forename: Jiasong
authors.initials: J
authors.lastname: Li
authors.forename: Michael
authors.initials: M
authors.lastname: Twa
authors.forename: Stanislav Y
authors.initials: SY
authors.lastname: Emelianov
authors.forename: Kirill V
authors.initials: KV
authors.lastname: Larin
mesh_terms: D000162:Acoustics; D001696:Biomechanical Phenomena; D004548:Elasticity; D006801:Humans; D008962:Models, Theoretical; D019047:Phantoms, Imaging; D013499:Surface Properties; D041623:Tomography, Optical Coherence; D014159:Transducers; D014465:Ultrasonics; D014783:Viscosity