title: [Species distribution of pathogens and prognostic factors for catheter-related bloodstream infections in intensive care unit].
abstract: OBJECTIVE
  To explore the incidence and species distribution of catheter-related bloodstream infection (CRBSI) in intensive care unit (ICU) at our hospital and analyze the risk factors for CRBSI.
  
  
  METHODS
  Hospitalized patients microbiologically diagnosed as CRBSI were recruited from January 2012 to June 2013. And the clinical data were collected retrospectively and analyzed by software IBM SPSS 19.0.
  
  
  RESULTS
  Among 67 patients diagnosed as nosocomial CRBSI, 24 cases (35.8%) died while 43 survived. And a total of 81 strains were detected, including 42 Gram-positive (G⁺) bacteria (51.9%), 36 Gram-negative (G⁻) bacteria (44.4%) and 3 fungi (3.7%).The predominant pathogenic G⁺ and G⁻ bacteria were Staphylococcus epidermidis and Acinetobacter baumannii respectively. With multiple Logistic regressions, age ≥ 65 years, higher acute physiology & chronic health evaluation II (APACHE II) score and polymicrobial CRBSI were independent predictors of worse outcomes.
  
  
  CONCLUSIONS
  The recent prevalent pathogens of CRBSI in ICU are S.epidermidis and A.baumannii. Advanced age, disease severity and polymicrobial CRBSI are significant independent risk factor of mortality for CRBSI patients in ICU.
authors.affiliation: Intensive Care Unit, Wuhan Central Hospital, Wuhan 430014, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.affiliation: Intensive Care Unit, Wuhan Central Hospital, Wuhan 430014, China; Email: yuli640006@sina.com.
authors.forename: Li
authors.initials: L
authors.lastname: Yu
authors.affiliation: Intensive Care Unit, Wuhan Central Hospital, Wuhan 430014, China.
authors.forename: Junhui
authors.initials: J
authors.lastname: Yang
authors.affiliation: Intensive Care Unit, Wuhan Central Hospital, Wuhan 430014, China.
authors.forename: Ding
authors.initials: D
authors.lastname: Long
authors.affiliation: Intensive Care Unit, Wuhan Central Hospital, Wuhan 430014, China.
authors.forename: Yuanchao
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Intensive Care Unit, Wuhan Central Hospital, Wuhan 430014, China.
authors.forename: Xiaofen
authors.initials: X
authors.lastname: Bu
mesh_terms: D016470:Bacteremia; D055499:Catheter-Related Infections; D003428:Cross Infection; D006801:Humans; D015994:Incidence; D007362:Intensive Care Units; D016015:Logistic Models; D015995:Prevalence; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors