title: Observation of the internal response of the kidney during compressive loading using ultrafast ultrasonography.
abstract: A protocol based on ultrafast ultrasonography was developed to study the internal response of isolated perfused human (n=3) and porcine (n=11) kidneys subjected to loading at 0.003 m/s and 0.3m/s respectively. Regional uniaxial strains were calculated based on natural target tracking. The effect of loading speed and regional differences could be statistically detected on the porcine specimens. However, despite the inhomogeneity of their anatomical structures, strains' responses appeared relatively homogeneous at 0.3m/s in both porcine and human kidneys. Failure, identified as a sudden change on the ultrasonography movie, also appeared at similar compression levels for both species (38.3% of applied strain in average for human and 35.8% of applied strain in average for porcine).
authors.affiliation: Université de Lyon, F--69622 Lyon, France; Université Claude Bernard Lyon 1, Villeurbanne, France; IFSTTAR, UMR_T9406, LBMC Laboratoire de Biomécanique et Mécanique des Chocs, F-69675 Bron, France.
authors.forename: C
authors.initials: C
authors.lastname: Helfenstein-Didier
authors.affiliation: Institut Langevin - Ondes et Images, ESPCI ParisTech, PSL Research University, CNRS UMR7587, INSERM U979, 1 rue Jussieu, 75238 Paris Cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Tanter
authors.affiliation: Institut Langevin - Ondes et Images, ESPCI ParisTech, PSL Research University, CNRS UMR7587, INSERM U979, 1 rue Jussieu, 75238 Paris Cedex, France.
authors.forename: J-L
authors.initials: JL
authors.lastname: Gennisson
authors.affiliation: Université de Lyon, F--69622 Lyon, France; Université Claude Bernard Lyon 1, Villeurbanne, France; IFSTTAR, UMR_T9406, LBMC Laboratoire de Biomécanique et Mécanique des Chocs, F-69675 Bron, France. Electronic address: Philippe.beillas@ifsttar.fr.
authors.forename: P
authors.initials: P
authors.lastname: Beillas
mesh_terms: D000818:Animals; D019245:Compressive Strength; D004867:Equipment Design; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000502:physiology*; D010477:Perfusion; D015203:Reproducibility of Results; D013314:Stress, Mechanical; D013552:Swine; D014463:Ultrasonography / Q000379:methods*
keywords: Internal strain.; Kidney; Ultrafast ultrasonography