title: The C57BL/6J Niemann-Pick C1 mouse model with decreased gene dosage is susceptible to increased weight gain when fed a high-fat diet: Confirmation of a gene-diet interaction.
authors.affiliation: Department of Biochemistry and Molecular Biology, School of Medicine, The University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
authors.forename: David
authors.initials: D
authors.lastname: Jelinek
authors.affiliation: Department of Biochemistry and Molecular Biology, School of Medicine, The University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
authors.forename: Joseph J
authors.initials: JJ
authors.lastname: Castillo
authors.affiliation: Department of Pediatrics, School of Medicine, The University of New Mexico Health Sciences Center, Albuquerque, NM, USA.
authors.forename: Randall A
authors.initials: RA
authors.lastname: Heidenreich
authors.affiliation: Department of Biochemistry and Molecular Biology, School of Medicine, The University of New Mexico Health Sciences Center, Albuquerque, NM, USA. Electronic address: wgarver@unm.edu.
authors.forename: William S
authors.initials: WS
authors.lastname: Garver
mesh_terms: D000818:Animals; D059305:Diet, High-Fat / Q000009:adverse effects*; D004195:Disease Models, Animal; D005260:Female; D018628:Gene Dosage; D059647:Gene-Environment Interaction; D047908:Intracellular Signaling Peptides and Proteins; D008297:Male; D008810:Mice, Inbred C57BL; D000077296:Niemann-Pick C1 Protein; D052556:Niemann-Pick Disease, Type C / Q000235:genetics*; D009765:Obesity / Q000235:genetics; D011506:Proteins / Q000235:genetics*; D015430:Weight Gain
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D000077296:Niemann-Pick C1 Protein; C106831:Npc1 protein, mouse; D011506:Proteins
keywords: Gene-diet interaction; Impaired glucose tolerance; Mouse model; Niemann–Pick C1; Weight gain