title: Rapidly progressive renal failure-a rare presentation of granulomatous interstitial nephritis due to tuberculosis-case report and review of literature.
abstract: Granulomatous interstitial nephritis (GIN) is a rare manifestation of renal tuberculosis (TB). We report a case of rapidly progressive renal failure (RPRF), granulomatous inflammation of cervical lymph node and GIN as presenting manifestations of TB. Aspiration cytology of cervical lymph node showed granulomatous necrotizing inflammation with acid-fast bacilli (AFB). The renal biopsy and urine specimen did not show AFB. Urine polymerase chain reaction (PCR) for Mycobacterium tuberculosis was positive. We observe that GIN due to TB can present as RPRF and emphasize the value of PCR-based techniques in making a correct diagnosis.
authors.affiliation: Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttarpradesh, India.
authors.forename: Anupma
authors.initials: A
authors.lastname: Kaul
authors.affiliation: Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttarpradesh, India.
authors.forename: Raj
authors.initials: R
authors.lastname: K Sharma
authors.affiliation: Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttarpradesh, India.
authors.forename: Jaisuresh
authors.initials: J
authors.lastname: Krishnasamy
authors.affiliation: Department of Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttarpradesh, India.
authors.forename: Vivek
authors.initials: V
authors.lastname: Ruhela
authors.affiliation: Department of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttarpradesh, India.
authors.forename: Niraj
authors.initials: N
authors.lastname: Kumari
keywords: granulomatous interstitial nephritis; rapidly progressive renal failure; renal tuberculosis