title: [Cholesterol associated to low density lipoproteins (LDL) and vascular risk reduction. Proprotein convertase subtilisin/kexin type 9 (PCSK9): A new therapeutic target].
authors.affiliation: Unidad de Medicina Interna, Consulta de Riesgo Vascular, Hospital Universitario Fundación Alcorcón, Universidad Rey Juan Carlos, Madrid, España. Electronic address: cguijarro@fhalcorcon.es.
authors.forename: Carlos
authors.initials: C
authors.lastname: Guijarro
authors.affiliation: Instituto de Investigación, Unidad de Hipertensión, Hospital Universitario 12 de Octubre, Madrid, España.
authors.forename: Luis Miguel
authors.initials: LM
authors.lastname: Ruilope
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized; D015415:Biomarkers / Q000378:metabolism; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006937:Hypercholesterolemia / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism*; D006951:Hyperlipoproteinemias / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008077:Lipoproteins, LDL / Q000235:genetics / Q000378:metabolism*; D000071449:Proprotein Convertase 9; D043484:Proprotein Convertases / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D040242:Risk Reduction Behavior; D012697:Serine Endopeptidases / Q000235:genetics / Q000378:metabolism*; D016896:Treatment Outcome
chemical_list: D000911:Antibodies, Monoclonal; D061067:Antibodies, Monoclonal, Humanized; D015415:Biomarkers; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D000960:Hypolipidemic Agents; D008077:Lipoproteins, LDL; C472125:PCSK9 protein, human; D000071449:Proprotein Convertase 9; D043484:Proprotein Convertases; D012697:Serine Endopeptidases; C577155:evolocumab; C571059:alirocumab