title: Challenges and climate of business environment and resources to support pediatric device development.
abstract: The incidence of pediatric disease conditions pales in comparison to adult disease. Consequently, many pediatric disorders are considered orphan diseases. Resources for the development of devices targeting orphan diseases are scarce and this poses a unique challenge to the development of pediatric devices. This article outlines these challenges and offers solutions.
authors.affiliation: Department of Surgery, Children's Mercy Hospital, Kansas City, Missouri. Electronic address: ciqbal@cmh.edu.
authors.forename: Corey W
authors.initials: CW
authors.lastname: Iqbal
authors.affiliation: Department of Surgery, Lucille-Packard Children's Hospital Stanford, Palo Alto, California.
authors.forename: James
authors.initials: J
authors.lastname: Wall
authors.affiliation: Division of Pediatric Surgery, University of California San Francisco, 513 Parnassus Ave, San Francisco, California 94143.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Harrison
mesh_terms: D004867:Equipment Design / Q000191:economics; D004864:Equipment and Supplies / Q000191:economics*; D006801:Humans; D010372:Pediatrics / Q000295:instrumentation*; D035583:Rare Diseases / Q000628:therapy*
keywords: Innovation; Orphan device; Pediatrics