title: An Effect of Oak-Wood Extract (Robuvit®) on Energy State of Healthy Adults-A Pilot Study.
abstract: The purpose of our study was to examine the psychological benefits of the treatment with Robuvit® (Horphag Research Ltd.) - polyphenolic extract obtained from the wood of oak Quercus robur - on the healthy elderly individuals using energy subscale scores of the Activation - Deactivation Adjective Check List. Analysis was focused on the comparison of pre-post treatment effect of Robuvit on symptoms of fatigue. In the total group of volunteers, significant increase of average question scores was found in three of four subscales of feelings (energy, tiredness, and tension) after 4 weeks of Robuvit administration. Effects of extract were observed mainly after stratification of total group of volunteers according to the level of feeling at the pre-treatment questionnaire. Our results demonstrate positive effect of Robuvit on mental and energy level in healthy human without any unwanted side effects.
authors.affiliation: Institute of Medical Chemistry, Biochemistry and Clinical Biochemistry, Medical Faculty, Comenius University in Bratislava, Bratislava, Slovakia.
authors.forename: Zuzana
authors.initials: Z
authors.lastname: Országhová
authors.affiliation: Department of Nuclear Physics and Biophysics, Faculty of Mathematics, Physics and Informatics, Comenius University in Bratislava, Bratislava, Slovakia.
authors.forename: Iveta
authors.initials: I
authors.lastname: Waczulíková
authors.affiliation: Horphag Research, Avenue Louis-Casaï 71, 1216, Cointrin/Geneva, Switzerland.
authors.forename: Carolina
authors.initials: C
authors.lastname: Burki
authors.affiliation: Westfälische Wilhelms-Universität Münster, Institut für Pharmazeutische Chemie, Twenteweg 15, 48161, Münster, Germany.
authors.forename: Peter
authors.initials: P
authors.lastname: Rohdewald
authors.affiliation: Institute of Medical Chemistry, Biochemistry and Clinical Biochemistry, Medical Faculty, Comenius University in Bratislava, Bratislava, Slovakia.
authors.forename: Zdeňka
authors.initials: Z
authors.lastname: Ďuračková
mesh_terms: D000328:Adult; D000368:Aged; D005221:Fatigue; D006801:Humans; D047348:Hydrolyzable Tannins / Q000494:pharmacology*; D008875:Middle Aged; D010865:Pilot Projects; D010936:Plant Extracts / Q000494:pharmacology*; D029963:Quercus / Q000737:chemistry*; D011795:Surveys and Questionnaires; D014934:Wood / Q000737:chemistry*
chemical_list: D047348:Hydrolyzable Tannins; D010936:Plant Extracts; C588251:Robuvit
keywords: Quercus robur; Robuvit; ellagitannins; fatigue; roburins