title: Rh(III)-Catalyzed Direct Coupling of Azobenzenes with α-Diazo Esters: Facile Synthesis of Cinnolin-3(2H)-ones.
abstract: The rhodium(III)-catalyzed direct C-H functionalization of azobenzenes with α-diazo compounds is described. These transformations provide the facile and efficient construction of C2-alkylated azobenzenes or highly substituted cinnolin-3(2H)-ones. Furthermore, this protocol leads to the formation of cinnolin-3(2H)-ones using a diazo derivative of Meldrum's acid.
authors.affiliation: †School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
authors.forename: Satyasheel
authors.initials: S
authors.lastname: Sharma
authors.affiliation: †School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Han
authors.affiliation: †School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
authors.forename: Sangil
authors.initials: S
authors.lastname: Han
authors.affiliation: †School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
authors.forename: Wontae
authors.initials: W
authors.lastname: Ji
authors.affiliation: †School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
authors.forename: Jongchan
authors.initials: J
authors.lastname: Oh
authors.affiliation: †School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
authors.forename: Seok-Yong
authors.initials: SY
authors.lastname: Lee
authors.affiliation: ‡College of Pharmacy, Dankook University, Cheonan 330-714, Republic of Korea.
authors.forename: Joa Sub
authors.initials: JS
authors.lastname: Oh
authors.affiliation: †School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
authors.forename: Young Hoon
authors.initials: YH
authors.lastname: Jung
authors.affiliation: †School of Pharmacy, Sungkyunkwan University, Suwon 440-746, Republic of Korea.
authors.forename: In Su
authors.initials: IS
authors.lastname: Kim
mesh_terms: D001391:Azo Compounds / Q000737:chemistry*; D002384:Catalysis; D004146:Dioxanes / Q000737:chemistry*; D004952:Esters; D006574:Heterocyclic Compounds, 2-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*
chemical_list: D001391:Azo Compounds; D004146:Dioxanes; D004952:Esters; D006574:Heterocyclic Compounds, 2-Ring; C076489:Meldrum's acid; D012238:Rhodium; C009850:azobenzene; C476282:cinnoline