title: Public interest in and acceptability of the prospect of risk-stratified screening for breast and prostate cancer.
abstract: BACKGROUND
  For risk-stratified screening to be implemented as a screening program for breast and prostate cancer it has to be accepted among the general population. Investigating public interest in stratified screening and its acceptability to the public is therefore essential since as yet little is known.
  
  
  METHODS
  Cross-sectional web survey sent to a sample of 10 000 individuals (20-74 years of age) representative of the Swedish population as registered in 2009.
  
  
  RESULTS
  Among the responders (28%), a vast majority (94%) expressed an interest in knowing their breast or prostate cancer risk and stated wanting to know to 'avoid worrying'. Men and women were equally interested in knowing their prostate and breast cancer risk, respectively. However, men showed more certainty. Trusting the healthcare workers with personal information (63%) as well as genetic information (70%), in order to calculate the risk, did not seem to be a major issue. Furthermore, 87% would agree to get screened more often if identified with a high risk, whereas, if identified with a low risk, only 27% would agree to get screened less often. Finally, although a consultation with a physician seemed to be the preferred way to communicate the risk, a majority would agree to receive it via a letter or a phone call.
  
  
  CONCLUSIONS
  Risk-stratified screening has the possibility to be accepted by the general public. Knowledge about interest and acceptability of the prospect of risk-stratified screening for breast and prostate cancer will help when implementing new screening strategies.
authors.affiliation: a Karolinska Institutet, Department of Oncology-Pathology , Karolinska University Hospital , Stockholm , Sweden.
authors.forename: Marie
authors.initials: M
authors.lastname: Koitsalu
authors.affiliation: b Department of Medical Psychology , Academic Medical Center, University of Amsterdam , Amsterdam , The Netherlands.
authors.forename: Mirjam A G
authors.initials: MA
authors.lastname: Sprangers
authors.affiliation: c Department of Medical Epidemiology and Biostatistics , Karolinska Institutet , Stockholm , Sweden.|d Department of Surgery , UCSF Comprehensive Cancer Center , San Francisco, California , USA.
authors.forename: Martin
authors.initials: M
authors.lastname: Eklund
authors.affiliation: c Department of Medical Epidemiology and Biostatistics , Karolinska Institutet , Stockholm , Sweden.
authors.forename: Kamila
authors.initials: K
authors.lastname: Czene
authors.affiliation: c Department of Medical Epidemiology and Biostatistics , Karolinska Institutet , Stockholm , Sweden.
authors.forename: Per
authors.initials: P
authors.lastname: Hall
authors.affiliation: c Department of Medical Epidemiology and Biostatistics , Karolinska Institutet , Stockholm , Sweden.
authors.forename: Henrik
authors.initials: H
authors.lastname: Grönberg
authors.affiliation: a Karolinska Institutet, Department of Oncology-Pathology , Karolinska University Hospital , Stockholm , Sweden.
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Brandberg
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis*; D003142:Communication; D003430:Cross-Sectional Studies; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006282:Health Personnel; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods* / Q000458:organization & administration / Q000523:psychology; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000175:diagnosis*; D011639:Public Opinion; D018570:Risk Assessment / Q000379:methods*; D012737:Sex Factors; D011795:Surveys and Questionnaires; D013548:Sweden; D035502:Trust