title: First Direct Observation of Stable Internally Ordered Janus Nanoparticles Created by Lipid Self-Assembly.
abstract: We present the first observation of Janus nanoparticles consisting of stable, coexisting ordered mesophases in discrete particles created by lipid self-assembly. Cryo-TEM images provided visual identification of the multicompartment Janus nanoparticles and, combined with SAXS data, confirmed the presence of mixed cubic phases and mixed cubic/hexagonal phases within individual nanoparticles. We further investigated computer visualization models to interpret the potential interface between the interconnected coexisting nanostructured domains within a single nanoparticle.
authors.affiliation: †CSIRO, Manufacturing Flagship, Clayton, Victoria 3168, Australia.|‡SAXS/WAXS Beamline, Australian Synchrotron, Clayton, Victoria 3168, Australia.
authors.forename: Nhiem
authors.initials: N
authors.lastname: Tran
authors.affiliation: †CSIRO, Manufacturing Flagship, Clayton, Victoria 3168, Australia.
authors.forename: Xavier
authors.initials: X
authors.lastname: Mulet
authors.affiliation: ‡SAXS/WAXS Beamline, Australian Synchrotron, Clayton, Victoria 3168, Australia.
authors.forename: Adrian M
authors.initials: AM
authors.lastname: Hawley
authors.affiliation: ∥School of Applied Sciences, College of Science, Engineering and Health, RMIT University, Melbourne, Victoria 3000 Australia.
authors.forename: Charlotte E
authors.initials: CE
authors.lastname: Conn
authors.affiliation: †CSIRO, Manufacturing Flagship, Clayton, Victoria 3168, Australia.
authors.forename: Jiali
authors.initials: J
authors.lastname: Zhai
authors.affiliation: §CSIRO, Manufacturing Flagship, Parkville, Victoria 3052, Australia.
authors.forename: Lynne J
authors.initials: LJ
authors.lastname: Waddington
authors.affiliation: ∥School of Applied Sciences, College of Science, Engineering and Health, RMIT University, Melbourne, Victoria 3000 Australia.
authors.forename: Calum J
authors.initials: CJ
authors.lastname: Drummond
keywords: Janus nanoparticles; cubosome; hexosome; lipid self-assembly; lyotropic liquid crystal; polymorphism