title: Effect of manual acupuncture on bowel motility in normal kunming mouse.
abstract: OBJECTIVE
  To observe the effects of acupuncture on motility of jejunum and distal colon at different acupoints on normal Kunming mice.
  
  
  METHODS
  The jejunal and colorectal motor activity of forty Kunming mice were recorded by the intra-intestinal capsule. The capsules contained with distilled water were placed into the cavities of jejunum and distal colon. The changes of bowel were compared with the background activity recorded before any stimulation. The chosen acupoints were as follows: Zusanli (ST 36) on the lower legs, Tianshu (ST 25) on the mid-lower abdomen.
  
  
  RESULTS
  Manual acupuncture (MA) at Zusanli (ST 36) significantly promoted the motility of jejunum and distal colon (manifested as increased change rate of average amplitude and increased change rate of mean area under the contractile curve) of normal Kunming mice (P < 0.01). MA at Tianshu (ST 25) significantly inhibited the motility of jejunum (manifested as decreased change rate of average amplitude, decreased change rate of mean area under the contractile curve, and the reduced frequency) of normal Kunming mice (P < 0.01), while significantly increased the distal colonic motility (manifested as increased amplitude and increased mean area under the contractile curve) of normal Kunming mice (P < 0.01).
  
  
  CONCLUSIONS
  MA at specific acupoints [Zusanli (ST 36), Tianshu (ST 25)] has different effects on the motility of jejunum and distal colon, which might involve the segmental innervations of the related nerve.
authors.forename: Zhao
authors.initials: Z
authors.lastname: Yuxue
authors.forename: Cui
authors.initials: C
authors.lastname: Changxiang
authors.forename: Qin
authors.initials: Q
authors.lastname: Qingguang
authors.forename: Ben
authors.initials: B
authors.lastname: Hui
authors.forename: Gao
authors.initials: G
authors.lastname: Junhong
authors.forename: Yu
authors.initials: Y
authors.lastname: Xiaochun
authors.forename: Zhu
authors.initials: Z
authors.lastname: Bing
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy; D000818:Animals; D003106:Colon / Q000502:physiology*; D005260:Female; D005769:Gastrointestinal Motility; D007583:Jejunum / Q000502:physiology*; D008297:Male; D051379:Mice