title: Cancers of the nose, sinus, and skull base.
abstract: Malignancies of the nose, sinus, and skull base are rare. The most common histologies are squamous cell carcinoma and adenocarcinoma. The most common primary sites are the nasal cavity and maxillary sinus. Management of these tumors is technically challenging because they often present in advanced stages with extensive disease invading important structures such as the orbit and the skull base. In the last few decades advances in surgical resection techniques, as well as improved strategies to deliver adjuvant radiation, have substantially improved the outcomes in patients with malignancies of the sinonasal tract and skull base.
authors.affiliation: Department of Otolaryngology, Weill Cornell Medical College, 1320 York Avenue, New York, NY 10021, USA.
authors.forename: Victoria
authors.initials: V
authors.lastname: Banuchi
authors.affiliation: Hofstra North Shore-LIJ School of Medicine, 500 Hofstra University, Hempstead, NY 11549, USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Mallen
authors.affiliation: The Center for Head & Neck Oncology, New York Head & Neck Institute, North Shore-LIJ Cancer Institute, 130 East 77th Street, Black Hall 10th Floor, New York, NY 10075, USA; The Center for Thyroid & Parathyroid Surgery, New York Head and Neck Institute, New York, NY, USA. Electronic address: DKraus@NSHS.edu.
authors.forename: Dennis
authors.initials: D
authors.lastname: Kraus
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D009669:Nose Neoplasms / Q000473:pathology* / Q000628:therapy; D010255:Paranasal Sinus Neoplasms / Q000473:pathology* / Q000628:therapy; D011379:Prognosis; D019292:Skull Base Neoplasms / Q000473:pathology* / Q000628:therapy
keywords: Nasal carcinoma; Sinonasal carcinoma; Sinonasal malignancies; Skull base cancers