title: Rasagiline and rapid symptomatic motor effect in Parkinson's disease: review of literature.
abstract: Rasagiline is a monoamine oxidase type-B inhibitor used as monotherapy or in addition to levodopa in the treatment of Parkinson's disease. Once daily administration of rasagiline makes it easy to use, and allows good compliance by patients and adherence to therapy. Several multicenter studies have noted the effectiveness of rasagiline on both motor and non-motor symptoms, which require a complex pharmacologic approach, such as cognitive disorders. A recent study also reported a rapid action of rasagiline on motor symptoms. Positive findings have been highlighted by an economic model study. This review analyzes the main studies of rasagiline, with particular attention to the effectiveness of the drug on motor symptoms.
authors.affiliation: Department of Neurology, Santorso Hospital, Vicenza, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Pistacchi
authors.affiliation: Rehabilitation Hospital of High Specialization, Neurology and Neurophysiology, Motta di Livenza (TV), Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Martinello
authors.affiliation: Department of Neurology, San Martino Hospital, Belluno, Italy.
authors.forename: Manuela
authors.initials: M
authors.lastname: Gioulis
authors.affiliation: Department of Neurology, San Martino Hospital, Belluno, Italy.
authors.forename: Sandro
authors.initials: S
authors.lastname: Zambito Marsala
keywords: Monoamine oxidase type-B inhibitor; Motor symptoms; Neurology; Parkinson’s disease; Rasagiline