title: Diabetes and related metabolic conditions in an aboriginal cree community of quebec, Canada.
abstract: OBJECTIVE
  We evaluated the prevalence of type 2 diabetes, obesity and metabolic syndrome according to International Diabetes Federation criteria in the First Nations Cree community of Mistissini, Quebec.
  
  
  METHODS
  A cross-sectional study of 172 adults was performed as part of a broader regional environmental study.
  
  
  RESULTS
  Type 2 diabetes, hyperinsulinemia and abdominal obesity were documented in 20%, 70% and 91% of participants, respectively. The prevalence of metabolic syndrome was 54%, with the main profile including abnormal plasma glucose levels (60%) associated with high triacylglycerol (40%). Women displayed the highest prevalence of abdominal obesity (99%). In both sexes, waist circumference was clearly associated with other metabolic parameters, such as blood glucose and lipid profile (p<0.0001). However, a significant proportion of the population (13%), especially women, showed high waist circumference with no metabolic disturbances.
  
  
  CONCLUSIONS
  Among the Cree population of Mistissini, the results suggest that the high prevalence of abdominal obesity occurs most frequently in women, and earlier in women than in men. Subsequent metabolic disturbances associated with metabolic syndrome develop with age, supporting the core role of abdominal obesity in the cascade of events leading to diabetes and cardiovascular disease.
authors.affiliation: School of Dietetics and Human Nutrition, McGill University, Ste-Anne de Bellevue, Quebec, Canada; Axe Sante des Population et Environnement, Centre de Recherche du CHUQ, Centre hospitalier de l'Universite Laval, Quebec, Canada. Electronic address: marie-ludivine.chateau-degat@crchul.ulaval.ca.
authors.forename: Marie-Ludivine
authors.initials: ML
authors.lastname: Chateau-Degat
authors.affiliation: Axe Sante des Population et Environnement, Centre de Recherche du CHUQ, Centre hospitalier de l'Universite Laval, Quebec, Canada.
authors.forename: Daria
authors.initials: D
authors.lastname: Pereg
authors.affiliation: School of Dietetics and Human Nutrition, McGill University, Ste-Anne de Bellevue, Quebec, Canada.
authors.forename: Grace M
authors.initials: GM
authors.lastname: Egeland
authors.affiliation: McMaster University, Department of Biochemistry and Biological Science, Hamilton, Ontario, Canada; University of Tromsø, Institute of Community Medicine, Tromsø, Norway.
authors.forename: Evert
authors.initials: E
authors.lastname: Nieboer
authors.affiliation: Cree Board of Health and Social Services of James Bay, Chisasibi, Quebec, Canada.
authors.forename: Yv
authors.initials: Y
authors.lastname: Bonnier-Viger
authors.affiliation: Axe Sante des Population et Environnement, Centre de Recherche du CHUQ, Centre hospitalier de l'Universite Laval, Quebec, Canada.
authors.forename: Elhadji A
authors.initials: EA
authors.lastname: Laouan-Sidi
authors.affiliation: Cree Board of Health and Social Services of James Bay, Chisasibi, Quebec, Canada.
authors.forename: David
authors.initials: D
authors.lastname: Dannenbaum
authors.affiliation: Axe Sante des Population et Environnement, Centre de Recherche du CHUQ, Centre hospitalier de l'Universite Laval, Quebec, Canada.
authors.forename: Eric
authors.initials: E
authors.lastname: Dewailly
keywords: : adiposite; Indiens de l'Amérique du Nord; North American Indians; adiposity; cardiovascular risk; diabete; diabetes; metabolic syndrome; obesity; obésité; risque cardiovasculaire; syndrome métabolique