title: Baclofen overdose from possible intrinsic malfunction of SynchroMed II pump.
abstract: This is a case report illustrating an overdose of baclofen in a 10-year-old boy due to a likely malfunction of a SynchroMed II pump. This ultimately necessitated a pump replacement. One-year follow-up showed no further incidents of baclofen overdose, with multiple pump refills.
authors.affiliation: Department of Neurosurgery, Penn State Hershey Medical Center, Hershey, Pennsylvania.
authors.forename: Justin R
authors.initials: JR
authors.lastname: Davanzo
authors.affiliation: Department of Neurosurgery, Penn State Hershey Medical Center, Hershey, Pennsylvania.
authors.forename: Elias
authors.initials: E
authors.lastname: Rizk
mesh_terms: D001418:Baclofen / Q000008:administration & dosage*; D002547:Cerebral Palsy / Q000188:drug therapy* / Q000209:etiology; D002648:Child; D020878:Device Removal; D062787:Drug Overdose / Q000209:etiology* / Q000628:therapy; D004868:Equipment Failure; D058786:GABA-B Receptor Agonists / Q000008:administration & dosage*; D006801:Humans; D015918:Infusion Pumps, Implantable / Q000009:adverse effects*; D060186:Infusions, Spinal; D007969:Leukomalacia, Periventricular / Q000150:complications; D008297:Male; D012008:Recurrence
chemical_list: D058786:GABA-B Receptor Agonists; D001418:Baclofen
keywords: baclofen; functional neurosurgery; overdose; pump