title: Amberinone, a new guaianolide from Amberboa ramosa.
abstract: The Amberboa is a medicinally important genus present in the family Asteraceae; members of this genus are mainly distributed in Pakistan and India. It has been used in different systems of traditional medicines for different diseases. Amberinone (1), a new sesquiterpene lactone, has been isolated from the ethyl acetate (EtOAc) soluble fraction of Amberboa ramosa together with chrysin (2), quercitine (3), eriodictyol (4) and keamferol (5). This is the first report of these compounds from this species. The structures of the isolated compounds have been elucidated by 1D and 2D (1)H (13)C NMR spectroscopy.
authors.affiliation: a Department of Applied Chemistry & Biochemistry , Government College University , Faisalabad 38000 , Pakistan.|b HEJ Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, University of Karachi , Karachi 75270 , Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ibrahim
authors.affiliation: d Department of Botany , Government College University , Faisalabad 38000 , Pakistan.
authors.forename: Iqbal
authors.initials: I
authors.lastname: Hussain
authors.affiliation: b HEJ Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, University of Karachi , Karachi 75270 , Pakistan.
authors.forename: Nusrat
authors.initials: N
authors.lastname: Hussain
authors.affiliation: a Department of Applied Chemistry & Biochemistry , Government College University , Faisalabad 38000 , Pakistan.
authors.forename: Arruje
authors.initials: A
authors.lastname: Hameed
authors.affiliation: a Department of Applied Chemistry & Biochemistry , Government College University , Faisalabad 38000 , Pakistan.
authors.forename: Tahir
authors.initials: T
authors.lastname: Farooq
authors.affiliation: b HEJ Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, University of Karachi , Karachi 75270 , Pakistan.
authors.forename: Amjad
authors.initials: A
authors.lastname: Hussain
authors.affiliation: c College of Pharmaceutical Sciences, Institute of Pharmacology, Toxicology and Biochemical Pharmaceutics, Zhejiang University , Hangzhou , China.
authors.forename: Muhammad Sajid Hamid
authors.initials: MS
authors.lastname: Akash
authors.affiliation: b HEJ Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, University of Karachi , Karachi 75270 , Pakistan.
authors.forename: Shabbir
authors.initials: S
authors.lastname: Hussain
mesh_terms: D000085:Acetates; D019659:Asteraceae / Q000737:chemistry; D007194:India; D009682:Magnetic Resonance Spectroscopy; D008518:Medicine, East Asian Traditional; D015394:Molecular Structure; D010154:Pakistan; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification; D012997:Solvents; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared
chemical_list: D000085:Acetates; D012717:Sesquiterpenes; D012997:Solvents; C007650:ethyl acetate
keywords: Amberboa ramosa; Asteraceae; amberinone; guaianolide