title: Rituximab in two cases of Goodpasture's syndrome.
abstract: We describe the effects of rituximab in two patients with refractory Goodpasture's syndrome. After one single 1000 mg dose administration, rituximab did not appear to improve renal function in either of our cases. Polyoma virus-negative leukoencephalopathy, a probable toxic side effect of rituximab, was seen in our first patient.
authors.affiliation: Division of Nephrology, Medical Department , University Hospital, Ulm.
authors.forename: Birgit
authors.initials: B
authors.lastname: Schless
authors.affiliation: Division of Nephrology, Medical Department , University Hospital, Ulm.
authors.forename: Suzan
authors.initials: S
authors.lastname: Yildirim
authors.affiliation: Division of Nephrology, Medical Department , University Hospital, Ulm.
authors.forename: Daniel
authors.initials: D
authors.lastname: Beha
authors.affiliation: Division of Nephrology, Medical Department , University Hospital, Ulm.
authors.forename: Frieder
authors.initials: F
authors.lastname: Keller
authors.affiliation: Department of Internal Medicine VI, Clinical Pharmacology and Pharmacoepidemiology , University Hospital Heidelberg , Heidelberg , Germany.
authors.forename: David
authors.initials: D
authors.lastname: Czock
keywords: Goodpasture’s syndrome; anti-GBM disease; leukoencephalopathy; plasma exchange; rituximab