title: The effect of adjustable suture (Khaw) trabeculectomy on intraocular pressure: a retrospective case series.
abstract: The aim of the study is to investigate long-term intraocular pressure (IOP) outcome as well as complications associated with adjustable suture trabeculectomy in glaucoma patients who were uncontrolled under maximum medical therapy. In this retrospective case series, 35 eyes of 30 patients are included in the study. Adjustable suture trabeculectomy with 0.2 mg/cc mitomycin-C for 3 min was performed by the same surgeon. Subconjunctival 5-fluorouracil injection, transconjunctival suture adjustment, digital massage, and/or argon suturolysis were utilized postoperatively as needed. Complete success, qualified success, and failure were defined as IOP ≤ 18 mmHg without medication, IOP ≤ 18 mmHg with one or more medications, and IOP >18 mmHg with medication or need for additional glaucoma surgery, respectively. Of the 35 eyes, 13 had primary open angle, 18 had psuedoexfoliative, 1 had juvenile, 1 had pigmentary, 1 had uveitic, and 1 had chronic angle-closure glaucoma. Mean preoperative IOP of 30.1 ± 10.5 mmHg dropped to 10.8 ± 4.7 mmHg (p < 0.001) after a mean follow-up of 595 ± 435 days. Nine eyes had the desired IOP on first postoperative day where no transconjunctival suture adjustment was performed. Remaining 26 eyes required a mean of two adjustments (range 1-7) during the first postoperative 24 days in order to achieve a desirable IOP. Complete success, qualified success, and failure were observed in 28 (80 %), 5 (14 %), and 2 (6 %) eyes, respectively. There were no serious complications related to adjustable suture trabeculectomy. We believe adjustable suture trabeculectomy to be a safe and effective alternative to standard trabeculectomy where a desirable low IOP can be achieved.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, 09100, Aydin, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kaplan
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, 09100, Aydin, Turkey. tolgakocaturk@gmail.com.
authors.forename: Tolga
authors.initials: T
authors.lastname: Kocatürk
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, 09100, Aydin, Turkey.
authors.forename: Volkan
authors.initials: V
authors.lastname: Dayanır
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000477:Alkylating Agents / Q000627:therapeutic use; D005260:Female; D005901:Glaucoma / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000627:therapeutic use; D011183:Postoperative Complications; D012189:Retrospective Studies; D013536:Suture Techniques; D014065:Tonometry, Ocular; D014130:Trabeculectomy / Q000009:adverse effects / Q000379:methods*; D014792:Visual Acuity
chemical_list: D000477:Alkylating Agents; D016685:Mitomycin
keywords: Adjustable suture; Mitomycin-C; Trabeculectomy