title: Does moderate intensity exercise attenuate the postprandial lipemic and airway inflammatory response to a high-fat meal?
abstract: We investigated whether an acute bout of moderate intensity exercise in the postprandial period attenuates the triglyceride and airway inflammatory response to a high-fat meal (HFM) compared to remaining inactive in the postprandial period. Seventeen (11 M/6 F) physically active (≥ 150 min/week of moderate-vigorous physical activity (MVPA)) subjects were randomly assigned to an exercise (EX; 60% VO 2peak) or sedentary (CON) condition after a HFM (10 kcal/kg, 63% fat). Blood analytes and airway inflammation via exhaled nitric oxide (eNO) were measured at baseline, and 2 and 4 hours after HFM. Airway inflammation was assessed with induced sputum and cell differentials at baseline and 4 hours after HFM. Triglycerides doubled in the postprandial period (~113 ± 18%, P < 0.05), but the increase did not differ between EX and CON. Percentage of neutrophils was increased 4 hours after HFM (~17%), but the increase did not differ between EX and CON. Exhaled nitric oxide changed nonlinearly from baseline to 2 and 4 hours after HFM (P < 0.05, η (2) = 0.36). Our findings suggest that, in active individuals, an acute bout of moderate intensity exercise does not attenuate the triglyceride or airway inflammatory response to a high-fat meal.
authors.affiliation: Department of Kinesiology, Kansas State University, 1A Natatorium, Manhattan, KS 66506, USA.
authors.forename: Stephanie P
authors.initials: SP
authors.lastname: Kurti
authors.affiliation: Department of Human Nutrition, Kansas State University, Manhattan, KS 66506, USA.
authors.forename: Sara K
authors.initials: SK
authors.lastname: Rosenkranz
authors.affiliation: College of Medicine, Department of Clinical Biomedical Science, Florida Atlantic University, Boca Raton, FL 33431, USA.
authors.forename: Morton
authors.initials: M
authors.lastname: Levitt
authors.affiliation: Department of Human Nutrition, Kansas State University, Manhattan, KS 66506, USA.
authors.forename: Brooke J
authors.initials: BJ
authors.lastname: Cull
authors.affiliation: Department of Human Nutrition, Kansas State University, Manhattan, KS 66506, USA.
authors.forename: Colby S
authors.initials: CS
authors.lastname: Teeman
authors.affiliation: Department of Human Nutrition, Kansas State University, Manhattan, KS 66506, USA.
authors.forename: Sam R
authors.initials: SR
authors.lastname: Emerson
authors.affiliation: Department of Kinesiology, Kansas State University, 1A Natatorium, Manhattan, KS 66506, USA.
authors.forename: Craig A
authors.initials: CA
authors.lastname: Harms
mesh_terms: D000328:Adult; D059305:Diet, High-Fat / Q000009:adverse effects*; D015444:Exercise; D005260:Female; D006801:Humans; D007249:Inflammation / Q000097:blood / Q000473:pathology*; D008055:Lipids / Q000097:blood*; D008168:Lung / Q000473:pathology*; D008297:Male; D062407:Meals; D009504:Neutrophils / Q000378:metabolism; D019518:Postprandial Period; D014280:Triglycerides / Q000097:blood
chemical_list: D008055:Lipids; D014280:Triglycerides