title: SnO2 Nanosheet/Nanoparticle Detector for the Sensing of 1-Nonanal Gas Produced by Lung Cancer.
abstract: A sensor has been developed for detecting 1-nonanal gas present in the breath of lung cancer patients by combining SnO2 nanosheets with SnO2 nanoparticles and noble metal catalysts. A significant change in the electrical resistance of this sensor was observed with increasing 1-nonanal gas concentration; the resistance decreased by a factor of 1.12 within the range of 1 to 10 ppm at 300 °C. The recovery of the sensor's resistance after detecting 1-nonanal gas concentrations of 0.055, 0.18, 1, and 9.5 ppm was determined to be 86.1, 84.2, 80.4 and 69.2%, respectively. This high sensitivity is attributed to the accelerated oxidation of 1-nonanal molecules caused by the (101) crystal faces of the SnO2 nanosheets and should provide a simple and effective approach to the early detection of lung cancer.
authors.affiliation: National Institute of Advanced Industrial Science and Technology (AIST), 2266-98 Anagahora, Shimoshidami, Moriyama-ku, Nagoya 463-8560, Japan.
authors.forename: Yoshitake
authors.initials: Y
authors.lastname: Masuda
authors.affiliation: National Institute of Advanced Industrial Science and Technology (AIST), 2266-98 Anagahora, Shimoshidami, Moriyama-ku, Nagoya 463-8560, Japan.
authors.forename: Toshio
authors.initials: T
authors.lastname: Itoh
authors.affiliation: National Institute of Advanced Industrial Science and Technology (AIST), 2266-98 Anagahora, Shimoshidami, Moriyama-ku, Nagoya 463-8560, Japan.
authors.forename: Woosuck
authors.initials: W
authors.lastname: Shin
authors.affiliation: National Institute of Advanced Industrial Science and Technology (AIST), 2266-98 Anagahora, Shimoshidami, Moriyama-ku, Nagoya 463-8560, Japan.
authors.forename: Kazumi
authors.initials: K
authors.lastname: Kato
mesh_terms: D000447:Aldehydes / Q000032:analysis*; D005740:Gases / Q000737:chemistry*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000378:metabolism; D053768:Metal Nanoparticles / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D010084:Oxidation-Reduction; D013052:Spectrometry, X-Ray Emission; D017971:Tin Compounds / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D005740:Gases; D017971:Tin Compounds; C008664:nonanal; C045358:stannic oxide