title: [Investigation on the causes of increased hepatitis E cases reported in Guizhou province].
abstract: OBJECTIVE
  To analyze causes of growing hepatitis E (HE) cases reported in Guizhou province, and probe into existing problems faced by medical institutions in diagnosis of clinical and laboratory-confirmed cases, for the purpose of improving the quality of HE surveillance system.
  
  
  METHODS
  Six hospitals reporting greater HE cases from 2007 to 2011 were pinpointed, whose reported cases rose suddenly in 2011. Such cases were investigated by means of impatient medical record review, results of laboratory test and clinician interview.
  
  
  RESULTS
  136 of the 354 reported HE cases investigated were found compliant with the diagnostic criteria of HE with an accordance rate of 38.42%. Difference of the HE diagnostic accordance rate among individual years, hospitals and reporting departments was statistically significant. Such rate of hospital reports was found to be the lowest in 2011, ranging from 0 to 18.18% respectively; HE cases reported by non-infectious departments accounted for 61.30% of total cases reported, with its accordance rate considerably below the infectious departments (8.29%). HE positive cases and HE positive rate in 2011 were significantly higher than that of preceding years.
  
  
  CONCLUSIONS
  Such increase of reported HE cases in 2011 in the province was mostly attributable to more HE laboratory tests made by the hospitals, yet the accordance rates were lower than satisfactory. In this regard, the medical institutions in question were advised to enhance their competency training for HE diagnosis and case report quality.
authors.affiliation: Key Laboratory of Surveillance and Early-warning on Infectious Disease, Division of Infectious Diseases; Chinese Field Epidemiology Training Project, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Guizhou Provincial Center for Disease Control and Prevention.
authors.forename: Guangpeng
authors.initials: G
authors.lastname: Tang
authors.affiliation: Chinese Field Epidemiology Training Project, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Huihui
authors.initials: H
authors.lastname: Liu
authors.affiliation: Guizhou Provincial Center for Disease Control and Prevention.
authors.forename: Zhiting
authors.initials: Z
authors.lastname: Zou
authors.affiliation: Chinese Field Epidemiology Training Project, Chinese Center for Disease Control and Prevention, Beijing 102206, China; Guizhou Provincial Center for Disease Control and Prevention.
authors.forename: Guanghai
authors.initials: G
authors.lastname: Yao
authors.affiliation: Chinese Field Epidemiology Training Project, Chinese Center for Disease Control and Prevention, Beijing 102206, China; Hunan Provincial Center for Disease Control and Prevention.
authors.forename: Jiehua
authors.initials: J
authors.lastname: Xiao
authors.affiliation: Chinese Field Epidemiology Training Project, Chinese Center for Disease Control and Prevention, Beijing 102206, China; Guizhou Guiyang Center for Disease Control and Prevention.
authors.forename: Rongheng
authors.initials: R
authors.lastname: Xie
authors.affiliation: Chinese Field Epidemiology Training Project, Chinese Center for Disease Control and Prevention, Beijing 102206, China; Email: mahl@chinacdc.cn.
authors.forename: Huilai
authors.initials: H
authors.lastname: Ma
mesh_terms: D002681:China / Q000453:epidemiology; D016751:Hepatitis E / Q000175:diagnosis / Q000453:epidemiology*; D006761:Hospitals; D006801:Humans; D007753:Laboratories; D012107:Research Design