title: Sleep-Wake Patterns of Adolescents with Borderline Personality Disorder and Bipolar Disorder.
abstract: Sleep-wake patterns are rarely examined in adolescents with borderline personality disorder (BPD) or bipolar disorder (BD). Within a developmental perspective, this study explores the sleep-wake cycle of adolescents aged 12-17 years with BPD or BD and healthy controls (HC) during periods with and without entrainment by school/work schedules. Eighteen euthymic BPD, six euthymic BD, and 20 HC adolescents wore wrist actigraphy during nine consecutive days to assess sleep-wake patterns. During school/work days, BPD adolescents spent more time awake when they were in bed compared to HC and BD adolescents (p = 0.039). On schedule-free days, BPD and BD youths spent more time in bed compared to HC adolescents (p = 0.015). BPD adolescents woke up over 1 h later compared to HC (p = 0.003). Total sleep time was more variable between nights in BPD adolescents compared to the HC group (p = 0.031). Future research should explore if sleep-wake pattern disruptions are a cause or a consequence of BPD symptomatology in adolescents. Addressing sleep-wake pattern during clinical assessment and treatment of BPD adolescents may potentially reduce their symptoms; this therapeutic effect still needs to be evaluated.
authors.affiliation: Sleep Laboratory and Clinic, Rivière-des-Prairies Hospital, 7070 Boul. Perras, Montréal, QC, H1E 1A4, Canada.|Mood Disorders Clinic and Research Branch, Rivière-des-Prairies Hospital, Montréal, QC, Canada.|Department of Psychiatry, Université de Montréal, Montréal, QC, Canada.|Research Centre, Rivière-des-Prairies Hospital and Institut Universitaire en Santé Mentale de Montréal, Montréal, QC, Canada.
authors.forename: Christophe
authors.initials: C
authors.lastname: Huỳnh
authors.affiliation: Mood Disorders Clinic and Research Branch, Rivière-des-Prairies Hospital, Montréal, QC, Canada.|Department of Psychiatry, Université de Montréal, Montréal, QC, Canada.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Guilé
authors.affiliation: Mood Disorders Clinic and Research Branch, Rivière-des-Prairies Hospital, Montréal, QC, Canada.|Department of Psychiatry, Université de Montréal, Montréal, QC, Canada.|Research Centre, Rivière-des-Prairies Hospital and Institut Universitaire en Santé Mentale de Montréal, Montréal, QC, Canada.
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Breton
authors.affiliation: Sleep Laboratory and Clinic, Rivière-des-Prairies Hospital, 7070 Boul. Perras, Montréal, QC, H1E 1A4, Canada. roger.godbout@umontreal.ca.|Department of Psychiatry, Université de Montréal, Montréal, QC, Canada. roger.godbout@umontreal.ca.|Research Centre, Rivière-des-Prairies Hospital and Institut Universitaire en Santé Mentale de Montréal, Montréal, QC, Canada. roger.godbout@umontreal.ca.
authors.forename: Roger
authors.initials: R
authors.lastname: Godbout
mesh_terms: D000293:Adolescent; D001714:Bipolar Disorder / Q000453:epidemiology; D001883:Borderline Personality Disorder / Q000453:epidemiology; D002940:Circadian Rhythm / Q000502:physiology; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D012890:Sleep / Q000502:physiology*; D012893:Sleep Wake Disorders / Q000453:epidemiology / Q000503:physiopathology*; D014851:Wakefulness / Q000502:physiology*
keywords: Actigraphy; Adolescent; Bipolar disorder; Borderline personality disorder; Circadian rhythm; Sleep