title: [Advance in prevention and treatment of ischemia cardio-cerebrovascular disease through increased therapeutic angiogenesis induced by traditional Chinese medicine].
abstract: Remaining organic and functional damage of ischemia cardio-cerebrovascular disease is always a main trouble puzzling the clinicians. After the discovery of endothelial progenitor cells (EPCs), researchers realize that postnatal angiogenesis is an important biological process, which play a key role to repair the ischemia tissue and improve the function. So a new concept which names therapeutic angiogenesis supply a new treament way for the ischemia cardio-cerebrovascular disease. Traditional Chinese medicine (TCM) has accumulated rich experience on treating the ischemia disease, studies found that many Chinese medicine prescriptions and effective ingredients can increase the therapeutic angiogenesis, howerer the mechanisms were not the same, they mainly manifest in regular the secretion of angiogenic factors, increase the proliferation and differentiation etc. In this paper, we review recent studies, summary the Chinese medicine prescriptions and effective ingredients which can increase the therapeutic angiogenesis, and analyze the differernt pathway. We view to provide reference for the later researchers.
authors.forename: Hao
authors.initials: H
authors.lastname: Guo
authors.forename: Lei
authors.initials: L
authors.lastname: Li
authors.forename: Jin-Cai
authors.initials: JC
authors.lastname: Hou
authors.forename: Jian-Xun
authors.initials: JX
authors.lastname: Liu
mesh_terms: D043925:Angiogenesis Inducing Agents / Q000008:administration & dosage*; D000818:Animals; D002545:Brain Ischemia / Q000188:drug therapy* / Q000503:physiopathology / Q000517:prevention & control; D002561:Cerebrovascular Disorders / Q000188:drug therapy* / Q000503:physiopathology / Q000517:prevention & control; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D006801:Humans
chemical_list: D043925:Angiogenesis Inducing Agents; D004365:Drugs, Chinese Herbal