title: Molecular epidemiological and phylogenetic analyses of canine parvovirus in domestic dogs and cats in Beijing, 2010-2013.
abstract: Fifty-five samples (15.62%) collected from dogs and cats were identified as canine parvovirus (CPV) infection in Beijing during 2010-2013. The nucleotide identities and aa similarities were 98.2-100% and 97.7-100%, respectively, when compared with the reference isolates. Also, several synonymous and non-synonymous mutations were also recorded for the first time. New CPV-2a was dominant, accounting for 90.90% of the samples. Two of the 16 samples collected from cats were identified as new CPV-2a (12.5%), showing nucleotide identities of 100% with those from dogs. Twelve samples (15.78%) collected from completely immunized dogs were found to be new CPV-2a, which means CPV-2 vaccines may not provide sufficient protection for the epidemic strains.
authors.affiliation: Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wu
authors.forename: Xin-Tao
authors.initials: XT
authors.lastname: Gao
authors.forename: Shao-Hua
authors.initials: SH
authors.lastname: Hou
authors.forename: Xiao-Yu
authors.initials: XY
authors.lastname: Guo
authors.forename: Xue-Shong
authors.initials: XS
authors.lastname: Yang
authors.forename: Wei-Feng
authors.initials: WF
authors.lastname: Yuan
authors.forename: Ting
authors.initials: T
authors.lastname: Xin
authors.forename: Hong-Fei
authors.initials: HF
authors.lastname: Zhu
authors.forename: Hong
authors.initials: H
authors.lastname: Jia
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000453:epidemiology / Q000821:virology*; D002415:Cats; D002681:China; D004283:Dog Diseases / Q000453:epidemiology / Q000821:virology*; D004285:Dogs; D005243:Feces; D017720:Molecular Epidemiology; D010322:Parvoviridae Infections / Q000097:blood / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D017993:Parvovirus, Canine / Q000235:genetics* / Q000302:isolation & purification; D010802:Phylogeny