title: Primary chondroblastic osteosarcoma of the breast.
abstract: Pure sarcomas of the breast are uncommon, accounting for less than 1% of primary breast malignant tumors. Mammary osteogenic sarcomas are very rare and less than 100 cases have been reported in literature. They mainly affect older and middle aged women and are highly aggressive. We report an additional case in a 56-year-old woman. Histological and immunohistological characteristics were similar to those described in other localizations. Differential diagnosis involves phyllodes sarcoma, breast metaplastic carcinoma with chondroid and osteoid differentiation, osteosarcoma of the ribs, and metastatic osteosarcoma. The prognosis is poor.
authors.affiliation: Department of Pathology, National Institute of Oncology, RABAT, MAROC.
authors.forename: Mohamed Reda
authors.initials: MR
authors.lastname: El Ochi
authors.forename: Fouad
authors.initials: F
authors.lastname: Zouaidia
authors.forename: Rachad
authors.initials: R
authors.lastname: Kabaj
authors.forename: Hafsa
authors.initials: H
authors.lastname: El Ouazzanni
authors.forename: Mohamed
authors.initials: M
authors.lastname: Allaoui
authors.forename: Mohamed
authors.initials: M
authors.lastname: Oukabli
authors.forename: Abderrahman
authors.initials: A
authors.lastname: Al Bouzidi
authors.forename: Basma
authors.initials: B
authors.lastname: El Khannoussi
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D019902:Chondrocytes / Q000737:chemistry / Q000473:pathology*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000556:secondary*; D008408:Mastectomy; D008875:Middle Aged; D012516:Osteosarcoma / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D011237:Predictive Value of Tests; D013997:Time Factors; D016896:Treatment Outcome; D016217:Ultrasonography, Mammary
chemical_list: D014408:Biomarkers, Tumor