title: Regulated cell death in diagnostic histopathology.
abstract: Regulated cell death (RCD) is a controlled cellular process, essential for normal development, tissue integrity and homeostasis, and its dysregulation has been implicated in the pathogenesis of various conditions including developmental and immunological disorders, neurodegenerative diseases, and cancer. In this review, we briefly discuss the historical perspective and conceptual development of RCD, we overview recent classifications and some of the key players in RCD; finally we focus on current applications of RCD in diagnostic histopathology.
authors.affiliation: Department of Pathology, University of Sarajevo Clinical Center, Sarajevo, Bosnia and Herzegovina.
authors.forename: Faruk
authors.initials: F
authors.lastname: Skenderi
authors.forename: Semir
authors.initials: S
authors.lastname: Vranic
authors.forename: Ivan
authors.initials: I
authors.lastname: Damjanov
mesh_terms: D017209:Apoptosis / Q000235:genetics / Q000502:physiology*; D015415:Biomarkers; D006706:Homeostasis; D006801:Humans; D007154:Immune System Diseases / Q000473:pathology*; D009369:Neoplasms / Q000473:pathology*; D019636:Neurodegenerative Diseases / Q000473:pathology*
chemical_list: D015415:Biomarkers