title: Prevalence and dynamics of antibodies against Toxoplasma gondii in kids born from naturally infected goats.
abstract: We investigated the presence of antibodies against Toxoplasma gondii in domesticated goats intended for human consumption in a rural suburb of Rajshahi, Bangladesh. Antibodies to T. gondii were found in 55.1% (80/145) of the goats tested in our sample. The seroprevalence among goats aged <1 year, 1-2 years, 2-3 years and ≥3 years were 36.7%, 66.0%, 59.1% and 100%, respectively. Our results demonstrated that seroprevalence increased with age. Among the seropositive goats, a subsample of eight free-ranging female goats with access to male goats was placed under continuous observation. During the observation period, these seropositive female goats delivered 11 kids, all of which were found to be seronegative before suckling colostrum. This finding strongly suggested that trans-placental infection rarely occurs in female goats that have acquired an infection before pregnancy. Our results indicate that infection via ingestion of oocysts plays a more important role than endogenous trans-placental infection in maintaining the endemicity of T. gondii among goats in Bangladesh.
authors.affiliation: Department of Animal Husbandry and Veterinary Science, Faculty of Agriculture, University of Rajshahi, Rajshahi-6205, Bangladesh. Electronic address: moizur@gmail.com.
authors.forename: Moizur
authors.initials: M
authors.lastname: Rahman
authors.affiliation: Department of Animal Husbandry and Veterinary Science, Faculty of Agriculture, University of Rajshahi, Rajshahi-6205, Bangladesh. Electronic address: alauddinbdru@gmail.com.
authors.forename: Md
authors.initials: M
authors.lastname: Alauddin
authors.affiliation: Department of Animal Husbandry and Veterinary Science, Faculty of Agriculture, University of Rajshahi, Rajshahi-6205, Bangladesh. Electronic address: mozaffor03@yahoo.com.
authors.forename: K M Mozaffor
authors.initials: KM
authors.lastname: Hossain
authors.affiliation: Department of Animal Husbandry and Veterinary Science, Faculty of Agriculture, University of Rajshahi, Rajshahi-6205, Bangladesh. Electronic address: hislam.islam@gmail.com.
authors.forename: Md Hemayetul
authors.initials: MH
authors.lastname: Islam
authors.affiliation: Department of Veterinary Parasitology, Faculty of Applied Biological Science, 1-1 Yanagido, Gifu 501-1193, Japan. Electronic address: k-kitoh@gifu-u.ac.jp.
authors.forename: Katsuya
authors.initials: K
authors.lastname: Kitoh
authors.affiliation: Division of Protozoology, Department of Parasitology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan. Electronic address: nagamune@nih.go.jp.
authors.forename: Kisaburo
authors.initials: K
authors.lastname: Nagamune
authors.affiliation: Department of Veterinary Parasitology, Faculty of Applied Biological Science, 1-1 Yanagido, Gifu 501-1193, Japan. Electronic address: atakashi@gifu-u.ac.jp.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Takashima
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D001459:Bangladesh / Q000453:epidemiology; D005260:Female; D018445:Infectious Disease Transmission, Vertical / Q000662:veterinary*; D008297:Male; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000662:veterinary*; D014122:Toxoplasma / Q000276:immunology*; D014124:Toxoplasmosis, Animal / Q000453:epidemiology / Q000276:immunology*
chemical_list: D000913:Antibodies, Protozoan
keywords: Bangladesh; Goat; Toxoplasma gondii; Trans-placental infection