title: Sweet's syndrome with pulmonary involvement: Case report and literature review.
abstract: A 74 year old female presented with fever, associated with papules and plaque in her upper and lower extremities. Exams revealed blood leukocytosis and a positive urine culture. Antibiotic therapy was initiated with no clinical response. After 1 week, chest X-ray showed right upper lobe alveolar infiltrate. A skin biopsy of the lesion showed infiltration by neutrophils, consistent with Sweet's Syndrome. Patient's condition progressively worsened, requiring oxygentherapy. Bronchoscopy and bronchoalveolar lavage were normal, transbronchial biopsies suggested lung involvement of Sweet 's syndrome. Antibiotic therapy was stopped. Corticosteroid were started. Therapy resulted in rapid clinical and radiological improvement.
authors.affiliation: Interventional Pulmonology, Clinica Alemana-Universidad del Desarrollo, Santiago, Manquehue Norte 1410, Chile.
authors.forename: S
authors.initials: S
authors.lastname: Fernandez-Bussy
authors.affiliation: Clinica Alemana-Universidad del Desarrollo, Santiago, Chile.
authors.forename: G
authors.initials: G
authors.lastname: Labarca
authors.affiliation: Universidad de Valparaiso, Santiago, Chile.
authors.forename: F
authors.initials: F
authors.lastname: Cabello
authors.affiliation: Interventional Pulmonology, Clinica Alemana-Universidad del Desarrollo, Santiago, Manquehue Norte 1410, Chile.
authors.forename: H
authors.initials: H
authors.lastname: Cabello
authors.affiliation: Division of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
authors.forename: E
authors.initials: E
authors.lastname: Folch
authors.affiliation: Division of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
authors.forename: A
authors.initials: A
authors.lastname: Majid
keywords: Lung disease; Neutrophilic infiltrates; Sweet's Syndrome; Transbronchial lung