title: Remineralizing Effect of Child Formula Dentifrices on Artificial Enamel Caries Using a pH Cycling Model.
abstract: OBJECTIVE
  Although fluoridated toothpastes are among the most accessible fluoride sources for caries prevention, their remineralization potential remains questionable. This study sought to compare the effects of 5 different child formula dentifrices on remineralization of artificial primary enamel caries using a pH cycling model.
  
  
  METHODS
  Twenty sound primary canine teeth were immersed in demineralizing solution for 96 hours to produce 100μm-deep artificial caries. The teeth were then longitudinally sectioned into 100-150 μm-thick slices and randomly divided into 5 groups and treated as follows: group A. Calcium phosphate toothpaste, group B. Pooneh children's toothpaste, group C. Biotin toothpaste, group D. Crest children's toothpaste and group E. Darougar children's toothpaste. The specimens underwent a pH cycling model for 10 days. The degree of demineralization before and after treatment and its changes were evaluated under a polarized light microscope and a stereomicroscope and data were statistically analyzed using repeated measures ANOVA and post-hoc test.
  
  
  RESULTS
  Stereomicroscopic analysis showed that only group C had a significant difference with other groups (P<0.001) and no significant differences were found between the remaining groups (P>0.05). Polarized light microscopic analysis revealed that in addition to group C, a significant difference was detected between groups A and B (P=0.02) and calcium phosphate toothpaste showed higher efficacy.
  
  
  CONCLUSIONS
  All the understudy toothpastes had remineralizing effect but calcium phosphate children's toothpaste had the highest and biotin toothpaste had the lowest efficacy.
authors.affiliation: Associate Professor, Department of Pediatric, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Beheshteh
authors.initials: B
authors.lastname: Malekafzali
authors.affiliation: Post Graduate Student, Department of Operative, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Maliheh
authors.initials: M
authors.lastname: Ekrami
authors.affiliation: Dental Student, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Armin
authors.initials: A
authors.lastname: Mirfasihi
authors.affiliation: Post Graduate Student, Department of Pediatric, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Abdolazimi
keywords: Fluoride; Tooth remineralization; Toothpastes