title: Donor Postoperative Biliary Complications After Living-Donor Liver Transplant.
abstract: OBJECTIVE
  Although the main factors responsible for donor deaths after living-donor liver transplant are liver failure and sepsis, the most common donor complications are associated with the biliary tract.
  
  
  METHODS
  Between April 2006 and May 2012, five hundred ninety-three donors underwent living-donor hepatectomy procedures for living-donor liver transplants. The mean age of donors was 31.0 ± 9.9 years and the ratio of men to women was 341:252. Of all donors, 533 (89.9%) underwent a right lobe hepatectomy, 45 (7.6%) underwent a left lateral segmentectomy, and 15 (2.5%) underwent a left hepatectomy.
  
  
  RESULTS
  Biliary complications were observed in 51 liver donors (8.6%). Based on the Clavien-Dindo classification, grade I and grade II complications were 3.2% and 0%, while grade IIIa and grade IIIb complications were observed in 3.5% and 1.85% of cases. Right lobe donor biliary complications occurred at the rate of 8.2% in 44 donors. Grade IV and grade V complications were not observed. Grade IIIa complications necessitating radiologic and endoscopic procedures were observed in 21 liver donors (3.5%). Bile leakage unresponsive to medical therapy was detected in 19 donors (3.2%). Nasobiliary catheters were placed in 3 of 19 donors and internal stents were placed in 1. Two sessions of balloon dilatation were performed in the 2 grade IIIb donors (0.33%). Biliary strictures observed in 2 right lobe donors and 1 left lobe donor was treated by hepaticojejunostomy an average of 14 months after surgery.
  
  
  CONCLUSIONS
  Avoidance of intraoperative issues and early recognition of bile leakage are fundamental in preventing complications in living-donor liver transplant donors.
authors.affiliation: From Inonu University, Department of Surgery and Liver Transplantation Unit, Malatya, Turkey.
authors.forename: Abuzer
authors.initials: A
authors.lastname: Dirican
authors.forename: Cengiz
authors.initials: C
authors.lastname: Ara
authors.forename: Koray
authors.initials: K
authors.lastname: Kutluturk
authors.forename: Mustafa
authors.initials: M
authors.lastname: Ozsoy
authors.forename: Mustafa
authors.initials: M
authors.lastname: Ates
authors.forename: Adil
authors.initials: A
authors.lastname: Baskiran
authors.forename: Burak
authors.initials: B
authors.lastname: Isik
authors.forename: Sezai
authors.initials: S
authors.lastname: Yilmaz
mesh_terms: D000328:Adult; D001660:Biliary Tract Diseases / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000009:adverse effects; D006801:Humans; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D011182:Postoperative Care; D011183:Postoperative Complications / Q000517:prevention & control