title: 4-(Dimethylamino)pyridine-catalysed iodolactonisation of γ,δ-unsaturated carboxylic acids.
abstract: 4-(Dimethylamino)pyridine functioned as an excellent catalyst for iodolactonisation reactions of γ,δ-unsaturated carboxylic acids, affording γ-lactones, δ-lactones, or both under neutral conditions at room temperature. The effects of substrate structures on the iodolactonisation were investigated, and a catalytic mechanism is proposed.
authors.affiliation: State Key Laboratory of Elemento-Organic Chemistry, Research Institute of Elemento-Organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Nankai University, Tianjin 300071, People's Republic of China. liuyuxiu@nankai.edu.cn wangqm@nankai.edu.cn wang98h@263.net.
authors.forename: Chuisong
authors.initials: C
authors.lastname: Meng
authors.forename: Zhihui
authors.initials: Z
authors.lastname: Liu
authors.forename: Yuxiu
authors.initials: Y
authors.lastname: Liu
authors.forename: Qingmin
authors.initials: Q
authors.lastname: Wang
mesh_terms: D002264:Carboxylic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D054879:Halogenation; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry; D008744:Methylamines / Q000138:chemical synthesis / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D007783:Lactones; D008744:Methylamines; C548437:N-methyl-1-(pyridin-2-yl)methanamine; D011725:Pyridines