title: Primary Burkitt lymphoma in the posterior mediastinum.
abstract: A 13-year-old boy was admitted to our hospital with complaints of posterior chest pain and dyspnea. Computed tomography and magnetic resonance imaging of the chest revealed a mass in the posterior mediastinum, extending from T8 to T11 with intraspinal involvement. A percutaneous core needle biopsy confirmed the diagnosis of Burkitt lymphoma. He was treated according to the Lymphoma Malignancy B protocol 2001 arm C3, but he presented with liver and brain relapses and died 7.5 months after admission. Although lymphoma is rarely localized in the posterior mediastinum, it should be considered in the differential diagnosis of posterior mediastinal masses in children.
authors.affiliation: Department of Cardiovascular and Thoracic Surgery, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Zied
authors.initials: Z
authors.lastname: Chaari
authors.affiliation: Department of Pathology, CHU Habib Bourguiba, Sfax, Tunisia charfislim@gmail.com.
authors.forename: Slim
authors.initials: S
authors.lastname: Charfi
authors.affiliation: Department of Cardiovascular and Thoracic Surgery, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Abdessalem
authors.initials: A
authors.lastname: Hentati
authors.affiliation: Department of Medical Oncology, CHU Habib Bourguiba, Sfax Tunisia.
authors.forename: Ines
authors.initials: I
authors.lastname: Ayadi
authors.affiliation: Department of Radiology, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Hanene
authors.initials: H
authors.lastname: Abid
authors.affiliation: Department of Cardiovascular and Thoracic Surgery, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Imed
authors.initials: I
authors.lastname: Frikha
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D062005:Biopsy, Large-Core Needle; D001932:Brain Neoplasms / Q000556:secondary; D002051:Burkitt Lymphoma / Q000737:chemistry / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D002637:Chest Pain / Q000209:etiology; D003937:Diagnosis, Differential; D004417:Dyspnea / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D008479:Mediastinal Neoplasms / Q000737:chemistry / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D011237:Predictive Value of Tests; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor
keywords: Adolescent; burkitt lymphoma; lymphoma; mediastinal neoplasms