title: Highly Cross-Linked Versus Conventional Polyethylene in Posterior-Stabilized Total Knee Arthroplasty at a Mean 5-Year Follow-up.
abstract: Concerns of highly cross-linked polyethylene (XLPE) in total knee arthroplasty (TKA) exist regarding fatigue resistance and oxidation, particularly in posterior-stabilized (PS) designs. A prospective cohort study of 114 consecutive PS TKAs utilized conventional polyethylene in 50 knees and second-generation annealed XLPE in 64 TKAs. Clinical (Short-Form 36, Knee Society Scores, and LEAS) and radiographic outcomes were evaluated at a mean of 5 years in 103 TKAs. Mean KSS scores were 12 points higher (P=0.01) and SF-36 physical function subset 14 points higher (P=0.005) in the XLPE group. There was no radiographic osteolysis or mechanical failure related to the tibial polyethylene in either group. At 5-year follow-up, no deleterious effects related to highly cross-linked posterior stabilized tibial polyethylene inserts were observed.
authors.affiliation: Indiana University Health Physicians, Indianapolis, Indiana; Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: R Michael
authors.initials: RM
authors.lastname: Meneghini
authors.affiliation: Indiana University Health Physicians, Indianapolis, Indiana; Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: Luke R
authors.initials: LR
authors.lastname: Lovro
authors.affiliation: Indiana University Health Physicians, Indianapolis, Indiana; Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: Shelly A
authors.initials: SA
authors.lastname: Smits
authors.affiliation: Indiana University Health Physicians, Indianapolis, Indiana; Indiana University School of Medicine, Indianapolis, Indiana.
authors.forename: Philip H
authors.initials: PH
authors.lastname: Ireland
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation*; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007719:Knee Joint; D007720:Knee Prosthesis / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D020959:Polyethylene / Q000737:chemistry*; D011446:Prospective Studies; D013977:Tibia
chemical_list: D020959:Polyethylene
keywords: annealed polyethylene; fatigue failure; highly-crosslinked; polyethylene; total knee arthroplasty; total knee replacement