title: [Vaginoplasty with autologous buccal micromucosa combined with acellular allogenic dermal matrix].
abstract: OBJECTIVE
  To introduce and evaluate the technical feasibility and anatomical and functional outcomes of one-stage vaginoplasty with autologous buccal micromucosa combined with acellular allogenic dermis.
  
  
  METHODS
  We retrospectively reviewed our experiences with 17 patients with Mayer- Rokitansky-Kuster-Hauser syndrome treated with primary surgery from September 2010 to April 2013. All patients underwent vaginoplasty with autologous buccal micromucosa combined with acellular allogenic dermis. We describe the details of this technique, observe the time of epithelization and evaluate the long- term anatomical, functional, and sexual outcomes.
  
  
  RESULTS
  The time of epithelization was 13 d (range: 12-15 d). At a mean follow-up of 15 months (range: 12-24 months), the mean postoperative dependence on the vaginal stent was 11.7 ± 1.64 months (range: 9-15 months), the mean depth of the neovagina was (9.0 ± 0.94) cm (range: 7-11 cm), the mean circumference was (12.3 ± 1.36) cm (range: 10.0-14.5 cm) and the mean volume was (105 ± 10) ml (range 85-120 ml). The mean female sexual function index score of the 12 sexually active patients was 29.5 ± 2.6. No spouse reported discomfort during intercourse.
  
  
  CONCLUSIONS
  Vaginoplasty with autologous buccal micromucosa combined with acellular allogenic dermis is an effective and feasible approach for patients with Mayer-Rokitansky-Kuster-Hauser syndrome. The procedure has satisfactory long-term anatomical and functional results. The use of the acellular allogenic dermis is limited by the high price and the potential infection.
authors.forename: Fenfyong
authors.initials: F
authors.lastname: Li
authors.forename: Senkai
authors.initials: S
authors.lastname: Li
authors.forename: Chuande
authors.initials: C
authors.lastname: Zhou
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhou
authors.forename: Jian
authors.initials: J
authors.lastname: Ding
authors.forename: Yujiao
authors.initials: Y
authors.lastname: Cao
authors.forename: Siya
authors.initials: S
authors.lastname: Zhang
authors.forename: Shuyi
authors.initials: S
authors.lastname: Wei
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhao
authors.forename: Qiang
authors.initials: Q
authors.lastname: Li
mesh_terms: D058489:46, XX Disorders of Sex Development / Q000601:surgery*; D062088:Acellular Dermis; D003075:Coitus; D000013:Congenital Abnormalities / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D009061:Mouth Mucosa / Q000637:transplantation*; D009095:Mullerian Ducts / Q000002:abnormalities* / Q000601:surgery; D011184:Postoperative Period; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D014621:Vagina / Q000002:abnormalities / Q000601:surgery*