title: Sagittal abdominal diameter as an anthropometric measure of cardiovascular and graft loss risk in renal transplant recipients.
abstract: BACKGROUND
  Sagittal abdominal diameter (SAD) has been presented as a stronger prognostic factor for all-cause and cardiovascular mortality in the general population. The aim of this study was to evaluate the relationship between SAD and its associated parameters in renal transplant recipients.
  
  
  METHODS
  One hundred eighty-one renal transplant recipients were enrolled in the study. All patients were evaluated according to standard clinical and biochemical parameters. Anthropometric measurements were performed for all patients. Pulse-wave velocity (PWV) was determined from pressure tracing over carotid and femoral arteries with the use of the Sphygmocor system.
  
  
  RESULTS
  Patients were divided into 2 groups according to SAD measurements. Group 1 (n = 127) was defined as SAD <24.3 cm, and group 2 (n = 54) was defined as SAD ≥ 24.3 cm. Patients in group 2 had significantly higher triglycerides, C-reactive protein (CRP), uric acid, systolic blood pressure, PWV, and body mass index measurements compared with group 1 (P < .05 for all). In group 2, estimated glomerular filtration rate (eGFR) was significantly lower than group 1 (P = .022). SAD had positive correlation with PWV, systolic and diastolic blood pressure, body mass index, triglycerides, fasting glucose, CRP, and uric acid (P < .05 for all). On stepwise linear regression analyses, proteinuria (P = .005), SAD (P = .001), and CRP (P = .015) independently predicted the degree of percentage change of eGFR.
  
  
  CONCLUSIONS
  Considering the significant association of visceral fat with inflammation and cardiovascular disease, estimating visceral fat by means of SAD could be a useful tool to stratify cardiovascular risk as well as graft function in renal transplant recipients.
authors.affiliation: Department of Nephrology, Baskent University Medical School, Ankara, Turkey. Electronic address: zeynepberkibal@gmail.com.
authors.forename: Z
authors.initials: Z
authors.lastname: Bal
authors.affiliation: Department of Nephrology, Baskent University Medical School, Ankara, Turkey.
authors.forename: M E
authors.initials: ME
authors.lastname: Uyar
authors.affiliation: Department of Nephrology, Baskent University Medical School, Ankara, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Tutal
authors.affiliation: Department of Nephrology, Baskent University Medical School, Ankara, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Guliyev
authors.affiliation: Department of Nephrology, Baskent University Medical School, Ankara, Turkey.
authors.forename: T
authors.initials: T
authors.lastname: Colak
authors.affiliation: Department of Nephrology, Baskent University Medical School, Ankara, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Sezer
authors.affiliation: Department of General Surgery, Baskent University Medical School, Ankara, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Haberal
mesh_terms: D000368:Aged; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D064346:Sagittal Abdominal Diameter / Q000502:physiology*; D066027:Transplant Recipients