title: Zinc-Catalyzed Functionalization of Si-H Bonds with 2-Furyl Carbenoids through Three-Component Coupling.
abstract: A three-component coupling of alk-2-ynals, 1,3-dicarbonyls and silanes is reported. ZnCl2 serves as an inexpensive and low-toxic catalyst for the overall transformation, which involves Knoevenagel condensation, cyclization, and carbene Si-H bond insertion. The process takes place with high atom economy in the absence of organic solvents and shows a broad scope. This reaction is also applicable to the functionalization of oligomeric siloxanes.
authors.affiliation: Departmento de Química Orgánica e Inorgánica e Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, C/Julián Clavería 8, 33006-Oviedo (Spain).
authors.forename: Sergio
authors.initials: S
authors.lastname: Mata
authors.affiliation: Departmento de Química Orgánica e Inorgánica e Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, C/Julián Clavería 8, 33006-Oviedo (Spain). lalg@uniovi.es.
authors.forename: Luis A
authors.initials: LA
authors.lastname: López
authors.affiliation: Departmento de Química Orgánica e Inorgánica e Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo, C/Julián Clavería 8, 33006-Oviedo (Spain). vicenteruben@uniovi.es.
authors.forename: Rubén
authors.initials: R
authors.lastname: Vicente
keywords: SiH bond functionalization; multicomponent reactions; oligosiloxanes; silanes; zinc catalysis