title: Usefulness of a new prognostic index for alcoholic hepatitis.
abstract: BACKGROUND
  Alcoholic liver disease is a major cause of end-stage liver disease worldwide and severe forms of alcoholic hepatitis are associated with a high short-term mortality. Objectives To analyze the importance of age-bilirubin-INR-creatinine (ABIC) score as an index of mortality and predictor for complications in patients with alcoholic hepatitis. To evaluate its correlation with those complications, with risk of death, as well as the scores model for end stage liver disease (MELD) and Maddrey's discriminat function.
  
  
  METHODS
  A total of 46 medical records of patients who had been hospitalized with alcoholic hepatitis were assessed retrospectively with lab tests on admission and after seven days. Score calculations were carried out and analyzed as well.
  
  
  RESULTS
  The scores showed positive reciprocal correlation and were associated with both hepatic encephalopathy and ascites. ABIC index, which was classified as high risk, presented as a risk factor for these complications and for death. In univariate logistic regression analysis of mortality, the ABIC index at hospital admission odds ratio was 19.27, whereas after 7 days, it was 41.29. The average survival of patients with ABIC of low and intermediate risk was 61.1 days, and for those with high risk, 26.2 days.
  
  
  CONCLUSIONS
  ABIC index is a predictor factor for complications such as ascites and hepatic encephalopathy, as well as for risk of death. Thus, it is a useful tool for clinical practice.
authors.affiliation: Departamento de Clínica - Gastroenterologia, Faculdade de Ciências Médicas, Universidade de Campinas, Campinas, SP, Brasil.
authors.forename: Jazon Romilson de Souza
authors.initials: JR
authors.lastname: Almeida
authors.affiliation: Departamento de Clínica - Gastroenterologia, Faculdade de Ciências Médicas, Universidade de Campinas, Campinas, SP, Brasil.
authors.forename: Roberta Chaves
authors.initials: RC
authors.lastname: Araújo
authors.affiliation: Departamento de Clínica - Gastroenterologia, Faculdade de Ciências Médicas, Universidade de Campinas, Campinas, SP, Brasil.
authors.forename: Giane Vieira de
authors.initials: GV
authors.lastname: Castilho
authors.affiliation: Departamento de Clínica - Gastroenterologia, Faculdade de Ciências Médicas, Universidade de Campinas, Campinas, SP, Brasil.
authors.forename: Letícia
authors.initials: L
authors.lastname: Stahelin
authors.affiliation: Departamento de Clínica - Gastroenterologia, Faculdade de Ciências Médicas, Universidade de Campinas, Campinas, SP, Brasil.
authors.forename: Lívia Dos Reis
authors.initials: Ldos R
authors.lastname: Pandolfi
authors.affiliation: Departamento de Clínica - Gastroenterologia, Faculdade de Ciências Médicas, Universidade de Campinas, Campinas, SP, Brasil.
authors.forename: Cecília Queiroz
authors.initials: CQ
authors.lastname: Silva
mesh_terms: D000328:Adult; D000368:Aged; D001663:Bilirubin / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D003404:Creatinine / Q000097:blood*; D005260:Female; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000097:blood / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D003404:Creatinine; D001663:Bilirubin