title: Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo.
abstract: Herein, we have developed a novel reversible two-photon fluorescent probe that is well suited for monitoring HOCl levels selectively and instantaneously. Results showed the reversible and instantaneous responses of the probe towards intracellular HOCl. Moreover, the probe was successfully applied to the imaging of the HOCl levels in zebrafish and mice via two-photon imaging.
authors.affiliation: College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China. tangb@sdnu.edu.cn.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.forename: Junqing
authors.initials: J
authors.lastname: kang
authors.forename: Jiaoyang
authors.initials: J
authors.lastname: Wang
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Bo
authors.initials: B
authors.lastname: Tang
mesh_terms: D000818:Animals; D002470:Cell Survival; D005456:Fluorescent Dyes / Q000737:chemistry*; D006997:Hypochlorous Acid / Q000737:chemistry* / Q000378:metabolism*; D042541:Intracellular Space / Q000378:metabolism; D051379:Mice; D057054:Molecular Imaging / Q000379:methods*; D017785:Photons; D000067996:RAW 264.7 Cells; D015027:Zebrafish
chemical_list: D005456:Fluorescent Dyes; D006997:Hypochlorous Acid