title: Hemostasis during urologic surgery: fibrin sealant compared with absorbable hemostat.
abstract: In the United States, fibrin sealants have been used to achieve hemostasis for nearly two decades. Although their clinical utility was first demonstrated in cardiac surgery, their effectiveness and safety have since been demonstrated to extend to a wide array of procedures. Fibrin sealants typically contain two components-fibrinogen and thrombin-that are combined and delivered simultaneously to a target bleeding site in order to achieve hemostasis. However, many commercial formulations contain other additional components, such as antifibrinolytic agents, that have been associated with adverse outcomes. This subanalysis compares the safety and effectiveness of a fibrin sealant versus an absorbable hemostat for achieving hemostasis during urologic procedures with mild to moderate bleeding.
authors.affiliation: Associated Medical Professionals, Syracuse, NY.
authors.forename: David M
authors.initials: DM
authors.lastname: Albala
authors.affiliation: Ethicon, Inc., Somerville, NJ.
authors.forename: Jerome B
authors.initials: JB
authors.lastname: Riebman
authors.affiliation: Ethicon, Inc., Somerville, NJ.
authors.forename: Richard
authors.initials: R
authors.lastname: Kocharian
authors.affiliation: Ethicon, Inc., Somerville, NJ.
authors.forename: Bogdan
authors.initials: B
authors.lastname: Ilie
authors.affiliation: Ethicon, Inc., Somerville, NJ.
authors.forename: John
authors.initials: J
authors.lastname: Albanese
authors.affiliation: Ethicon, Inc., Somerville, NJ.
authors.forename: Jessica
authors.initials: J
authors.lastname: Shen
authors.affiliation: Ethicon, Inc., Somerville, NJ.
authors.forename: Liza
authors.initials: L
authors.lastname: Ovington
authors.affiliation: Ethicon, Inc., Somerville, NJ.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Batiller
keywords: Fibrin tissue adhesive; Hemostasis; Hemostatics; Surgical technique; Urologic surgical procedures