title: ADAMTS-5 takes centre stage in new developments for aggrecanase inhibitors.
authors.affiliation: University of Melbourne, Murdoch Childrens Research Institute, Parkville, Vic 3052, Australia. Electronic address: amanda.fosang@mcri.edu.au.
authors.forename: A J
authors.initials: AJ
authors.lastname: Fosang
mesh_terms: D051722:ADAM Proteins / Q000276:immunology*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D002358:Cartilage, Articular / Q000473:pathology*; D006801:Humans; D010003:Osteoarthritis / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D051722:ADAM Proteins
keywords: ADAMTS-5; ADAMTS-5 inhibitor; Aggrecan; Aggrecanase; DMOAD; Disease-modifying OA drugs