title: Dual kidney transplantation: a single-center experience.
abstract: BACKGROUND
  Dual kidney transplantation (DKT) is an alternate approach to use marginal kidneys not suitable to be allocated for single kidney transplant. This retrospective study reviewed the short- and long-term outcomes regarding graft and patient survivals over a 9-year period at a single center.
  
  
  METHODS
  From 2005 to 2013, 33 DKTs were performed in our unit, where allocation was guided by clinical parameters mainly. The mean ages for recipients and donors were 58.6 ± 12.5 and 54.8 ± 13.6 years, respectively. Cold ischemia time was 21.4 ± 4 hours, and mean HLA mismatch for HLA-A, HLA-B, and HLA-DR was 3.06 ± 1.07. Immunosuppression regime was tacrolimus based.
  
  
  RESULTS
  Median follow-up time of 56 months showed patient and death-censored graft survivals at 1, 3, and 5 years to be 90% and 84%, 90% and 81%, and 84% and 81%, respectively. The rate of delayed graft function was 46.9% (n = 15), the rate of primary graft function was 46.9% (n = 15), the rate of and primary graft nonfunction was 6.2% (n = 2). Nineteen patients (59.4%) required biopsy: 12 of them showed acute tubular necrosis and 7 had rejection (1 needed graft removal, 4 were treated successfully with steroid and/or antithymocyte globulin, and 2 did not require treatment).
  
  
  CONCLUSIONS
  Outcomes of DKT in our center were satisfactory and similar to those of other transplant centers regarding patient and graft survivals.
authors.affiliation: Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom. Electronic address: yousifaawsaj@doctors.org.uk.
authors.forename: Y
authors.initials: Y
authors.lastname: Aawsaj
authors.affiliation: Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
authors.forename: T
authors.initials: T
authors.lastname: Dosani
authors.affiliation: Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
authors.forename: D
authors.initials: D
authors.lastname: Talbot
mesh_terms: D001706:Biopsy; D051799:Delayed Graft Function / Q000175:diagnosis*; D005260:Female; D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation / Q000379:methods*; D007683:Kidney Tubular Necrosis, Acute / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014019:Tissue Donors