title: Using the Effects of Youngsters' Eyesight on Quality of Life Questionnaire to Measure Visual Outcomes in Children With Uveitis.
abstract: OBJECTIVE
  The Effects of Youngsters' Eyesight on Quality of Life (EYE-Q) is a novel measure of vision-related quality of life (QOL) and function in children. We aim to determine the validity of the EYE-Q in childhood uveitis.
  
  
  METHODS
  We abstracted medical record data on arthritis and uveitis in a convenience sample of children with juvenile idiopathic arthritis (JIA) and/or uveitis. In addition to the EYE-Q, parents and patients completed questionnaires on overall QOL (Pediatric Quality of Life Inventory [PedsQL]), and physical functioning (Childhood Health Assessment Questionnaire [C-HAQ]).
  
  
  RESULTS
  Among 57 children (8 JIA, 24 JIA and uveitis, 25 uveitis alone), 102 ocular examinations were performed within 1 month of completing questionnaires. Uveitis patients had bilateral disease (69%), anterior involvement (78%), synechiae (51%), and cataracts (49%). Children with vision loss in their better eye (visual acuity [VA] 20/50 or worse) had worse EYE-Q (P = 0.006) and PedsQL (P = 0.028) scores, but not C-HAQ scores. The EYE-Q moderately correlated with logMAR VA (rs  = -0.43), PedsQL (rs  = 0.43), and C-HAQ (rs  = -0.45), but was not correlated with anterior chamber cells or intraocular pressure. The PedsQL and C-HAQ did not correlate with VA or cells. There were strong correlations between the parent and child EYE-Q (rs  = 0.62). Cronbach's α for the child report was 0.91. The EYE-Q had strong test-retest reliability (rs  = 0.75).
  
  
  CONCLUSIONS
  The EYE-Q may be an important tool in the assessment of visual outcomes in childhood uveitis and an improvement over general measures in detecting changes in vision-related function.
authors.affiliation: Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
authors.forename: Sheila T
authors.initials: ST
authors.lastname: Angeles-Han
authors.affiliation: Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Steven
authors.initials: S
authors.lastname: Yeh
authors.affiliation: Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Courtney
authors.initials: C
authors.lastname: McCracken
authors.affiliation: Children's Healthcare of Atlanta, Atlanta, Georgia.
authors.forename: Kirsten
authors.initials: K
authors.lastname: Jenkins
authors.affiliation: Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Daneka
authors.initials: D
authors.lastname: Stryker
authors.affiliation: Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Erica
authors.initials: E
authors.lastname: Myoung
authors.affiliation: Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
authors.forename: Larry B
authors.initials: LB
authors.lastname: Vogler
authors.affiliation: Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
authors.forename: Kelly
authors.initials: K
authors.lastname: Rouster-Stevens
authors.affiliation: Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Scott R
authors.initials: SR
authors.lastname: Lambert
authors.affiliation: Bristol-Myers Squibb, Princeton, New Jersey.
authors.forename: Melanie J
authors.initials: MJ
authors.lastname: Harrison
authors.affiliation: Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia.
authors.forename: Sampath
authors.initials: S
authors.lastname: Prahalad
authors.affiliation: Emory University School of Medicine and Rollins School of Public Health, Emory University, Atlanta, Georgia.
authors.forename: Carolyn
authors.initials: C
authors.lastname: Drews-Botsch
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011788:Quality of Life / Q000523:psychology; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014605:Uveitis / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy; D014787:Vision Tests / Q000379:methods / Q000592:standards; D014785:Vision, Ocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology*