title: [Hyperuricemia and renal risk].
abstract: Recent studies have revealed an association between elevated levels of uric acid and conditions correlated to chronic kidney diseases such as hypertension, cardiovascular and cerebral disease, insulin resistance. Several pathogenetic mechanisms at cellular and tissue levels could justify a direct correlation between serum uric acid levels and renal damage. Growing evidence indicating a correlation between urate lowering therapy and renal morbidity could encourage the use of urate lowering therapy in primary or secondary prevention in chronic kidney disease.
authors.forename: Francesca
authors.initials: F
authors.lastname: Viazzi
authors.forename: Barbara
authors.initials: B
authors.lastname: Bonino
authors.forename: Elena
authors.initials: E
authors.lastname: Ratto
authors.forename: Giovambattista
authors.initials: G
authors.lastname: Desideri
authors.forename: Roberto
authors.initials: R
authors.lastname: Pontremoli
mesh_terms: D006801:Humans; D033461:Hyperuricemia / Q000150:complications* / Q000378:metabolism; D051436:Renal Insufficiency, Chronic / Q000209:etiology*; D012307:Risk Factors; D014527:Uric Acid / Q000378:metabolism
chemical_list: D014527:Uric Acid