title: Nonsyndromic aplasia cutis congenita: a case report.
abstract: Aplasia cutis congenita (ACC) is a rare disorder, which is defined by the localized, or less commonly widespread absence of skin involving the epidermis, dermis and subcutaneous tissue with an incidence of 1/10.000 newborns. The underlying bone and dura mater can be also affected, and muscle and bone involvement occur in approximately 20 to 30% of the cases. Aplasia cutis congenita most often occurs in isolated form, but it has also been reported as part of a heterogeneous group of syndromes. Conservative treatment, surgery, or a combination of these has been described as possible treatment options. In the neonatal period, conservative treatment is more appropriate as a management strategy. We present a rare case of a 2-month old female patient with isolated aplasia cutis congenita, localized on the vertex of the scalp, treated conservatively since birth with good results.
authors.affiliation: Onkoderma-Policlinic for Dermatology and Dermatologic Surgery, Sofia Bulgaria.
authors.forename: A A
authors.initials: AA
authors.lastname: Chokoeva
authors.affiliation: Onkoderma-Policlinic for Dermatology and Dermatologic Surgery, Sofia Bulgaria.
authors.forename: G
authors.initials: G
authors.lastname: Tchernev
authors.affiliation: Department of General and Clinical Pathology, Department of Dermatology, University of Virginia Health System, Virginia, USA.
authors.forename: J W
authors.initials: JW
authors.lastname: Patterson
authors.affiliation: Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Wollina
authors.affiliation: Professor and Chair of Dermatology, University of Rome "G. Marconi", Rome, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Lotti