title: Functional outcome of macular edema in different retinal disorders.
abstract: Macular edema accompanies many ocular pathologies, affecting visual function and is an important factor in treatment decisions and disease outcome. Though visual acuity is commonly used to evaluate patient vision it does not always provide a complete estimate of their visual abilities or reflect their own visual perception. Furthermore, different pathologies result in macular edema causing a variable effect on visual function, related to the rate of fluid accumulation and accompanying ocular changes. Use of complementary visual function tests, such as retinal contrast sensitivity on microperimetry and reading speed provide additional information that can be used to evaluate patients and assist in treatment choices. Here we explore the effect of macular edema on visual function in different retinal pathologies, namely diabetic retinopathy, retinal vein occlusion and uveitis, examine its influence on the various vision tests and discuss the factors underlying this variable response.
authors.affiliation: Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, UK; UCL Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK; Royal Surrey County Hospital, Egerton Road, Guildford, Surrey GU2 7XX, UK; Bnai Zion Medical Center, 47 Golomb Road, Haifa 31048, Israel.
authors.forename: Oren
authors.initials: O
authors.lastname: Tomkins-Netzer
authors.affiliation: Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, UK; UCL Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK; Royal Surrey County Hospital, Egerton Road, Guildford, Surrey GU2 7XX, UK.
authors.forename: Filis
authors.initials: F
authors.lastname: Ismetova
authors.affiliation: Wolfson Medical Center, 62 HaLohamim Street, Holon, Israel.
authors.forename: Asaf
authors.initials: A
authors.lastname: Bar
authors.affiliation: Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, UK; Royal Surrey County Hospital, Egerton Road, Guildford, Surrey GU2 7XX, UK.
authors.forename: Sophie
authors.initials: S
authors.lastname: Seguin-Greenstein
authors.affiliation: Rabin Medical Center, Beilinson Campus, Petach Tikva 49100, Israel; Sackler School of Medicine, Tel-Aviv University, Tel- Aviv, Israel.
authors.forename: Michal
authors.initials: M
authors.lastname: Kramer
authors.affiliation: Moorfields Eye Hospital, 162 City Road, London EC1V 2PD, UK; UCL Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK; Royal Surrey County Hospital, Egerton Road, Guildford, Surrey GU2 7XX, UK. Electronic address: s.lightman@ucl.ac.uk.
authors.forename: Sue
authors.initials: S
authors.lastname: Lightman
mesh_terms: D015350:Contrast Sensitivity; D003930:Diabetic Retinopathy / Q000150:complications*; D006801:Humans; D008269:Macular Edema / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D012170:Retinal Vein Occlusion / Q000150:complications*; D014605:Uveitis / Q000150:complications*; D014787:Vision Tests / Q000379:methods; D014792:Visual Acuity / Q000502:physiology; D058609:Visual Field Tests; D014794:Visual Fields / Q000502:physiology
keywords: Best corrected visual acuity; Macular edema; Microperimetry; Reading speed; Retinal contrast sensitivity; Vision loss