title: Influence of adiposity on health-related quality of life in the Gateshead Millennium Study cohort: longitudinal study at 12 years.
abstract: OBJECTIVE
  To examine whether adiposity is associated with an impaired quality of life (an individual's perception of their life) in general population samples in early adolescence.
  
  
  METHODS
  Relationships between a direct measure of adiposity (fat mass index from bioimpedance) and a proxy measure (waist circumference), and a generic (KIDSCREEN-27) and a weight-specific measure of health-related quality of life (HRQoL, Impact of Weight on Quality of Life-Kids (IWQOL-Kids)) were examined in a longitudinal population-based cohort of young adolescents aged 12 years (n=519). The effects of change in adiposity over time (from 7 years and 9 years) were also examined (n=331-445 in longitudinal analyses).
  
  
  RESULTS
  Impairment in HRQoL was associated with current adiposity but it was not predicted by earlier adiposity. At 12 years, higher adiposity was associated with lower Physical Well-Being on KIDSCREEN-27, and with lower Total Scores on the weight-specific IWQOL-Kids instrument, the latter particularly in girls.
  
  
  CONCLUSIONS
  Health and education professionals need to be aware in their clinical practice that higher adiposity impairs HRQoL in general populations of young adolescents. Further research would be useful to determine whether or not children of primary school age self-reporting lower HRQoL are more likely to develop higher adiposity later in adolescence or early adulthood.
authors.affiliation: Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK Human Nutrition Research Centre, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Kathryn N
authors.initials: KN
authors.lastname: Parkinson
authors.affiliation: Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK Human Nutrition Research Centre, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Ashley J
authors.initials: AJ
authors.lastname: Adamson
authors.affiliation: Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK Human Nutrition Research Centre, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Laura
authors.initials: L
authors.lastname: Basterfield
authors.affiliation: Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK Human Nutrition Research Centre, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Jessica K
authors.initials: JK
authors.lastname: Reilly
authors.affiliation: Institute of Health & Society, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Ann
authors.initials: A
authors.lastname: Le Couteur
authors.affiliation: Physical Activity for Health Group, School of Psychological Sciences & Health, University of Strathclyde, Glasgow, UK.
authors.forename: John J
authors.initials: JJ
authors.lastname: Reilly
mesh_terms: D050154:Adiposity / Q000502:physiology*; D000886:Anthropometry / Q000379:methods; D002648:Child; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D050177:Overweight / Q000523:psychology* / Q000534:rehabilitation; D011594:Psychometrics; D011627:Puberty / Q000502:physiology; D011788:Quality of Life; D012649:Self Concept; D055105:Waist Circumference
keywords: Adolescent; Epidemiologic studies; Longitudinal studies; Overweight; Quality of life