title: Impact of periodontal conditions on the quality of life of pregnant women: a cross-sectional study.
abstract: BACKGROUND
  Studies have been rarely conducted to provide a comprehensive perspective of pregnant women with the intention to investigate the relationships between periodontal conditions and oral health-related quality of life (OHRQoL). As such, this study aimed to describe the OHRQoL of pregnant women in Shanghai, China and to investigate the relationships between periodontal conditions and OHRQoL of pregnant women.
  
  
  METHODS
  A cross-sectional study was conducted amongst pregnant women in all stages of pregnancy in Shanghai, China. Clinical examinations were performed to assess periodontal conditions, including tooth loss, visible plaque index, bleeding on probing, probing pocket depth and clinical attachment level. The OHRQoL of pregnant women was determined using the Oral Health Impact Profile (OHIP-14, Chinese version). Information regarding maternal characteristics, socio-demographic background and health-related behaviours was also obtained from the participants through the structured questionnaires.
  
  
  RESULTS
  A total of 512 pregnant women (mean age = 27.3 ± 4.0 years)participated in the survey,giving a response rate of 91.4 %. The mean gestational age was 19 weeks (SD = 8.2). The mean and the median OHIP-14 scores were 7.92 (SD = 6.84) and 6, respectively. The mean number of negative impact items (extent) was 0.20 (SD = 0.82). Approximately 10 % of pregnant women reported at least one item with 'fairly often' or 'very often' (prevalence). Results of multivariable analyses showed that periodontal conditions was not significantly associated with three scoring formats of OHRQoL (severity, extent and prevalence of impact) after adjustment for pregnancy-related variables and possible confounders (all p > 0.05). However, frequency of nausea-vomiting was found to be significantly associated with severity of impacts (p = 0.012). Utilization of dental services, age and tooth loss were the significant variables to the extent of negative impacts (all p < 0.05). While no significant variable was related with prevalence of negative impacts (p > 0.05).
  
  
  CONCLUSIONS
  Pregnant women with different trimesters showed similar impact of oral disease on their OHRQoL in Shanghai, China. Periodontal health status have no impact on their OHRQoL in the fully adjusted models. Their OHRQoL was associated with early pregnancy reaction, utilisation of dental services, age and tooth loss.
authors.affiliation: Department of Preventive Dentistry, Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China. ritalu0225@hotmail.com.
authors.forename: Hai-Xia
authors.initials: HX
authors.lastname: Lu
authors.affiliation: Department of Preventive Dentistry, Shanghai Municipal Hospital for Oral Health, Shanghai, China. weixu05@gmail.com.
authors.forename: Wei
authors.initials: W
authors.lastname: Xu
authors.affiliation: Dental Public Health, Faculty of Dentistry, University of Hong Kong, Hong Kong, China. mcmwong@hkucc.hku.hk.
authors.forename: May Chun Mei
authors.initials: MC
authors.lastname: Wong
authors.affiliation: Department of Preventive Dentistry, Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China. 261917090@qq.com.
authors.forename: Tian-You
authors.initials: TY
authors.lastname: Wei
authors.affiliation: Department of Preventive Dentistry, Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China. fengxiping_jtu@163.com.
authors.forename: Xi-Ping
authors.initials: XP
authors.lastname: Feng
mesh_terms: D000328:Adult; D000367:Age Factors; D002681:China; D003430:Cross-Sectional Studies; D003729:Dental Care; D005260:Female; D006304:Health Status; D006801:Humans; D009909:Oral Health; D010510:Periodontal Diseases / Q000150:complications* / Q000453:epidemiology / Q000523:psychology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000523:psychology; D015995:Prevalence; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016388:Tooth Loss; D055815:Young Adult