title: Anti-synthetase syndrome presenting as cryptogenic organizing pneumonia.
abstract: Interstitial lung disease (ILD) is a unique group of lung diseases that can be associated with inflammatory conditions, such as polymyositis-dermatomyositis (PM-DM). Presentation of PM-DM with ILD is not uncommon but clinical and radiological features can be similar to other conditions (e.g. atypical pneumonia) and can be challenging to diagnose. Delayed diagnosis of PM-DM can be associated with progression of pulmonary involvement and potentially increase morbidity. We report a patient presenting with pulmonary symptoms who had positive anti-Jo-1 antibodies and cryptogenic organizing pneumonia features on biopsy, which is a rare reported finding.
authors.affiliation: Department of Internal Medicine, Mayo Clinic College of Medicine, 200 1st St. S.W., Rochester, MN 55905, USA.
authors.forename: Qusay
authors.initials: Q
authors.lastname: Haydour
authors.affiliation: Department of Internal Medicine, Mayo Clinic College of Medicine, 200 1st St. S.W., Rochester, MN 55905, USA.
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Wells
authors.affiliation: Department of Internal Medicine, Mayo Clinic College of Medicine, 200 1st St. S.W., Rochester, MN 55905, USA.
authors.forename: Sara S
authors.initials: SS
authors.lastname: McCoy
authors.affiliation: Department of Internal Medicine, Mayo Clinic College of Medicine, 200 1st St. S.W., Rochester, MN 55905, USA.
authors.forename: Eric
authors.initials: E
authors.lastname: Nelsen
authors.affiliation: Division of Pulmonary and Critical Care, Mayo Clinic College of Medicine, 200 1st St. S.W., Rochester, MN 55905, USA.
authors.forename: Patricio
authors.initials: P
authors.lastname: Escalante
authors.affiliation: Divisions of Rheumatology and Epidemiology, Mayo Clinic College of Medicine, 200 1st St. S.W., Rochester, MN 55905, USA.
authors.forename: Eric L
authors.initials: EL
authors.lastname: Matteson
keywords: Anti-Jo-1 antibodies; Anti-synthetase syndrome; Cryptogenic organizing pneumonia; Interstitial lung disease; Polymyositis-dermatomyositis