title: [Biosynthesis of biologically active low-molecular weight compounds by fungi of the genus Penicillium (review)].
abstract: The recent data on exometabolite biosynthesis in fungi of the genus Penicillium is summarized. The study of creative species, as well as those isolated from extreme ecotopes, resulted in the identification of a number of novel, biologically active compounds. Alkaloid biosynthesis has been shown to begin on.the first day of fungus cultivation and to proceed throughout the cultivation period. Idiophase kinetics was observed for the biosynthesis of polyketide metabolites. The mechanisms of regulation of biosynthesis of promising bioactive compounds are discussed.
authors.forename: A G
authors.initials: AG
authors.lastname: Kozlovskii
authors.forename: T V
authors.initials: TV
authors.lastname: Antipova
authors.forename: V P
authors.initials: VP
authors.lastname: Zhelifonova
mesh_terms: D000470:Alkaloids / Q000096:biosynthesis; D003470:Culture Media; D017753:Ecosystem; D008970:Molecular Weight; D010407:Penicillium / Q000145:classification* / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism*; D064210:Secondary Metabolism
chemical_list: D000470:Alkaloids; D003470:Culture Media