title: Esophageal ulcer of unknown origin complicated by left atrial myxoma.
abstract: Myxoma induces the onset of paraneoplastic syndromes by excreting various humoral mediators and is therefore known to present with diverse symptoms. A 40-year-old woman was admitted to our hospital for the treatment of an esophageal ulcer, the cause of which could not be identified on various examinations. Notably, a left atrial tumor was incidentally found on chest enhanced computed tomography. The esophageal ulcer, which was intractable to conventional therapy, improved with the administration of 5-aminosalicylate, a drug known to inhibit IL-1β. This inhibitory action effectively suppressed the development of myxoma-induced paraneoplastic syndrome.
authors.affiliation: Department of Cardiology, Juntendo University Graduate School of Medicine, Juntendo Tokyo Koto Geriatric Medical Center, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Nishizaki
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Yamagami
authors.forename: Daisuke
authors.initials: D
authors.lastname: Hayakawa
authors.forename: Shiori
authors.initials: S
authors.lastname: Takashima
authors.forename: Osamu
authors.initials: O
authors.lastname: Nomura
authors.forename: Eiryu
authors.initials: E
authors.lastname: Sai
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Kon
authors.forename: Shujiro
authors.initials: S
authors.lastname: Matsuyama
authors.forename: Sumio
authors.initials: S
authors.lastname: Watanabe
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Daida
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D004935:Esophageal Diseases / Q000209:etiology / Q000473:pathology*; D005260:Female; D006325:Heart Atria / Q000473:pathology*; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D006801:Humans; D033162:Incidental Findings; D019804:Mesalamine / Q000008:administration & dosage*; D009232:Myxoma / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014456:Ulcer / Q000209:etiology / Q000473:pathology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine