title: Transfusion strategy for acute upper gastrointestinal bleeding.
abstract: Clinical question Does a hemoglobin transfusion threshold of 70 g/L yield better patient outcomes than a threshold of 90 g/L in patients with acute upper gastrointestinal bleeding? Article chosen Villanueva C, Colomo A, Bosch A, et al. Transfusion strategies for acute upper gastrointestinal bleeding. N Engl J Med 2013;368(1):11-21. Study objectives The authors of this study measured mortality, from any cause, within the first 45 days, in patients with acute upper gastrointestinal bleeding, who were managed with a hemoglobin threshold for red cell transfusion of either 70 g/L or 90 g/L. The secondary outcome measures included rate of further bleeding and rate of adverse events.
authors.affiliation: Division of Emergency Medicine,University of Calgary,Calgary,AB.
authors.forename: James
authors.initials: J
authors.lastname: Handel
authors.affiliation: Division of Emergency Medicine,University of Calgary,Calgary,AB.
authors.forename: Eddy
authors.initials: E
authors.lastname: Lang
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D001803:Blood Transfusion / Q000592:standards*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000401:mortality / Q000628:therapy*; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic; D012189:Retrospective Studies; D015996:Survival Rate / Q000639:trends
keywords: bleeding; gastrointestinal; transfusion