title: Opsoclonus-myoclonus syndrome associated with non-small cell lung cancer.
abstract: A 68-year-old man developed progressive vertigo, saccadic eye movements, and tremors. Computed tomography showed multiple lung nodules. Surgery was performed and the pathological diagnosis was large cell neuroendocrine carcinoma in the left upper lobe with ipsilobar metastases, and adenocarcinoma in the left lower lobe. The neurological symptoms resolved dramatically after complete resection of the tumors. Opsoclonus-myoclonus syndrome associated with non-small-cell lung carcinoma is extremely rare. Surgery should not be delayed if a complete resection is expected.
authors.affiliation: Department of Thoracic Surgery, JR Tokyo General Hospital, Tokyo, Japan tak.karasaki@gmail.com.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Karasaki
authors.affiliation: Department of Thoracic Surgery, JR Tokyo General Hospital, Tokyo, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Tanaka
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D000077192:Adenocarcinoma of Lung; D000368:Aged; D001706:Biopsy; D018287:Carcinoma, Large Cell / Q000150:complications* / Q000473:pathology / Q000601:surgery; D018278:Carcinoma, Neuroendocrine / Q000150:complications* / Q000473:pathology / Q000601:surgery; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications* / Q000473:pathology / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D008297:Male; D055613:Multiple Pulmonary Nodules / Q000150:complications* / Q000473:pathology / Q000601:surgery; D053578:Opsoclonus-Myoclonus Syndrome / Q000175:diagnosis / Q000209:etiology*; D011013:Pneumonectomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Adenocarcinoma; carcinoma; central nervous system; lung neoplasms; neuroendocrine; non-small-cell lung; opsoclonus-myoclonus syndrome