title: Travelling activity and travel-related risks after allogeneic haematopoietic stem cell transplantation - a single centre survey.
abstract: BACKGROUND
  Travel activity and travel-related risks of patients after allogeneic haematopoietic stem cell transplantation (allo-HSCT) remain largely unknown. The aim of our study was to examine travel activity after allo-HSCT including travel behaviour and travel patterns.
  
  
  METHODS
  We analysed travel characteristics of allo-HSCT recipients by using a retrospective cross-sectional survey. Allo-HSCT patients were asked to complete a questionnaire during their annual health visits from 2010 to 2012.
  
  
  RESULTS
  Overall, 118/153 (77%) participating patients reported travel activity for a total of 201 travelling episodes. Travellers versus non-travellers were receiving immunosuppressive treatment in 35.6% versus 65.7% (p=0.002), and had graft-versus-host-disease (GvHD) in 52.5% versus 62.9% (p=0.17). In a multivariate analysis, the time between the transplantation and the survey was the only factor associated with travel activity (p<0.0001) and taking pretravel advice (p<0.0001). In 34.8% of travel episodes pretravel advice was sought. Patients with pretravel advice reported travel-related symptoms more frequently. Minor respiratory (27/201) and gastrointestinal (23/201) symptoms were most frequently indicated. Four percent (8/201) of the patients were hospitalised while travelling.
  
  
  CONCLUSIONS
  We conclude that travelling after allo-HSCT is frequent and linked to the time since transplantation. We could not define specific risks for any destination. Nevertheless, pretravel advice and preparation are highly recommended for immunosuppressed patients.
authors.affiliation: Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Switzerland.
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Hollenstein
authors.affiliation: Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Switzerland.
authors.forename: Luigia
authors.initials: L
authors.lastname: Elzi
authors.affiliation: Swiss Tropical and Public Health Institute, Basel, Switzerland.
authors.forename: Christoph
authors.initials: C
authors.lastname: Hatz
authors.affiliation: Division of Haematology, University Hospital Basel, Switzerland.
authors.forename: Jakob
authors.initials: J
authors.lastname: Passweg
authors.affiliation: Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Switzerland.
authors.forename: Maja
authors.initials: M
authors.lastname: Weisser
authors.affiliation: Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Switzerland.
authors.forename: Marcel
authors.initials: M
authors.lastname: Stöckle
authors.affiliation: Division of Haematology, University Hospital Basel, Switzerland.
authors.forename: Joerg P
authors.initials: JP
authors.lastname: Halter
authors.affiliation: Clinical Microbiology, University Hospital Basel, Switzerland; Infection Biology, Department Biomedicine, University Basel, Switzerland.
authors.forename: Adrian
authors.initials: A
authors.lastname: Egli
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D037001:Directive Counseling; D005260:Female; D005767:Gastrointestinal Diseases / Q000453:epidemiology; D006086:Graft vs Host Disease / Q000453:epidemiology*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects / Q000706:statistics & numerical data*; D006760:Hospitalization; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D012140:Respiratory Tract Diseases / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D014184:Transplantation, Homologous; D014195:Travel / Q000706:statistics & numerical data*