title: Three New Sesquiterpene Aryl Esters from the Mycelium of Armillaria mellea.
abstract: Three new sesquiterpene aryl esters and eight known compounds were isolated from the EtOH extract of the mycelium of Armillaria mellea. The structures of new compounds were established by analysis of their spectroscopic data. Some of the isolates showed cytotoxicity to a variety of cancer cell lines, including MCF-7, H460, HT-29, and CEM.
authors.affiliation: Department of Biotechnology, HungKuang University, Sha Lu, Taichung 433, Taiwan. ccchen@sunrise.hk.edu.tw.|Department of Nursing, HungKuang University, Sha Lu, Taichung 433, Taiwan. ccchen@sunrise.hk.edu.tw.
authors.forename: Chien-Chih
authors.initials: CC
authors.lastname: Chen
authors.affiliation: Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan. kuoyh@mail.cmu.edu.tw.|Department of Biotechnology, Asia University, Taichung 413, Taiwan. kuoyh@mail.cmu.edu.tw.
authors.forename: Yueh-Hsiung
authors.initials: YH
authors.lastname: Kuo
authors.affiliation: National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Peitou, Taipei 112, Taiwan. verona@nricm.edu.tw.
authors.forename: Jing-Jy
authors.initials: JJ
authors.lastname: Cheng
authors.affiliation: Graduate Institute of Marine Biology, National Dong Hwa University, Pingtung 944, Taiwan. pjsung@nmmba.gov.tw.|National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan. pjsung@nmmba.gov.tw.
authors.forename: Ping-Jyun
authors.initials: PJ
authors.lastname: Sung
authors.affiliation: Department of Biotechnology, HungKuang University, Sha Lu, Taichung 433, Taiwan. alyssum15@yahoo.com.tw.
authors.forename: Ching-Li
authors.initials: CL
authors.lastname: Ni
authors.affiliation: Biotechnology Center, Grape King Bio Ltd., Chung Li, Taoyuan 320, Taiwan. gkbioeng@grapeking.com.tw.
authors.forename: Chin-Chu
authors.initials: CC
authors.lastname: Chen
authors.affiliation: National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Peitou, Taipei 112, Taiwan. ccshen@nricm.edu.tw.
authors.forename: Chien-Chang
authors.initials: CC
authors.lastname: Shen
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D055392:Armillaria / Q000737:chemistry*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D004317:Doxorubicin / Q000494:pharmacology; D004952:Esters; D000431:Ethanol / Q000737:chemistry; D019073:HT29 Cells; D006801:Humans; D061986:MCF-7 Cells; D015394:Molecular Structure; D025282:Mycelium / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D052616:Solid Phase Extraction; D012997:Solvents / Q000737:chemistry
chemical_list: D000970:Antineoplastic Agents; D004952:Esters; D012717:Sesquiterpenes; D012997:Solvents; D000431:Ethanol; D004317:Doxorubicin
keywords: Armillaria mellea; Tricholomataceae; cytotoxicity; sesquiterpene aryl esters