title: Facile Synthesis of Functionalized Carbene Metal Complexes from Coordinated Isonitriles.
abstract: The scope and limitations of the isonitrile-based NHC template synthesis were investigated with a series of precursors containing a nucleophilic amine in combination with tethered electrophiles. In the case of alkynes and phosphonic esters as electrophiles no ring closure was observed and new functionalized NAC gold complexes were obtained. By the use of unsaturated esters and phosphonic esters as Michael acceptors in the amine precursors, ester-modified gold and palladium NHC complexes were accessible in high efficiency.
authors.affiliation: Organisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120, Heidelberg, Germany), Fax: (+49) 06221-54-4205.
authors.forename: Christian
authors.initials: C
authors.lastname: Lothschütz
authors.affiliation: Organisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120, Heidelberg, Germany), Fax: (+49) 06221-54-4205.
authors.forename: Thomas
authors.initials: T
authors.lastname: Wurm
authors.affiliation: Organisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120, Heidelberg, Germany), Fax: (+49) 06221-54-4205.
authors.forename: Anna
authors.initials: A
authors.lastname: Zeiler
authors.affiliation: Organisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120, Heidelberg, Germany), Fax: (+49) 06221-54-4205.
authors.forename: Alexander
authors.initials: A
authors.lastname: Freiherr V Falkenhausen
authors.affiliation: Organisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120, Heidelberg, Germany), Fax: (+49) 06221-54-4205.
authors.forename: Matthias
authors.initials: M
authors.lastname: Rudolph
authors.affiliation: Organisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120, Heidelberg, Germany), Fax: (+49) 06221-54-4205.
authors.forename: Frank
authors.initials: F
authors.lastname: Rominger
authors.affiliation: Organisch-Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, 69120, Heidelberg, Germany), Fax: (+49) 06221-54-4205. hashmi@hashmi.de.
authors.forename: A Stephen K
authors.initials: AS
authors.lastname: Hashmi
keywords: Michael acceptors; amines; gold; isonitriles; phosphonates