title: In silico functional annotation of a hypothetical protein from Staphylococcus aureus.
abstract: Unknown proteins or hypothetical proteins exist but have not been characterized or linked to known genes. Domains of unknown function are experimentally identified proteins with no known functional or structural domain. In this paper, the investigation and characterization of the likely functional aspects of a hypothetical protein, YP_001317347.1, from Staphylococcus aureus was performed using various computational methods and tools. Based on the analysis, the protein has a YbbR domain and is expected to bind ribosomal subunits. The analysis reported here helps in understanding the importance of YbbR domains and will aid in the development of novel antibacterial agents.
authors.affiliation: Department of Computer Science & Engineering, SRKR Engineering College, Bhimavaram, Andhra Pradesh, India.
authors.forename: P
authors.initials: P
authors.lastname: Bharat Siva Varma
authors.affiliation: Department of Computer Science & Engineering, Sir C.R. Reddy College of Engineering, Eluru, Andhra Pradesh, India. Electronic address: yesubabuadimulam9@gmail.com.
authors.forename: Yesu B
authors.initials: YB
authors.lastname: Adimulam
authors.affiliation: Department of Computer Science and Systems Engineering, K.L. University, Vaddeswaram, Vijayawada, Andhra Pradesh, India.
authors.forename: Subrahmaniam
authors.initials: S
authors.lastname: Kodukula
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D019295:Computational Biology; D058977:Molecular Sequence Annotation; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D013211:Staphylococcus aureus / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins
keywords: Blast; Domains of unknown function; HHpred; Hypothetical protein