title: [ATl- and calcium-dependent mechanisms of salicy- lates influence on electric potentials of neurons in mollusk Helix albescens].
abstract: The article is devoted to investigation of mechanisms of salicylates influence on electric potentials in neurons of mollusk Helix albescens Rossm. It is shown that adenosinetriphosphate (5 x 10(-4) M) at the combined bath application with salicylates substantially modifies their neurotropic effects. It removes nonselective inhibition of impulse activity of neurons by acetylsalicylic acid and strengthens activating effects of cobalt and zinc acetylsalicylates. It is shown that at the blockade of Ca2+ entry by CdCl2 or BaCl2 (5 x 10(-5) and 5 x 10(-4) M) in a neuron from extracellular space or from intracellular depot do not change significantly neuronal responses to salicylates, what suggests that calcium mechanisms did not participate in these responses.
authors.forename: I V
authors.initials: IV
authors.lastname: Cheretaev
authors.forename: I
authors.initials: I
authors.lastname: Koreniuk
authors.forename: D R
authors.initials: DR
authors.lastname: Khusainov
authors.forename: T V
authors.initials: TV
authors.lastname: Gamma
authors.forename: O I
authors.initials: OI
authors.lastname: Kolotilova
authors.forename: A D
authors.initials: AD
authors.lastname: Nozdrachev
mesh_terms: D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism*; D003035:Cobalt / Q000494:pharmacology; D004560:Electricity; D006372:Helix, Snails / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D012459:Salicylates / Q000494:pharmacology*; D015032:Zinc / Q000494:pharmacology
chemical_list: D012459:Salicylates; D003035:Cobalt; D015032:Zinc; D001241:Aspirin; D002118:Calcium