title: Contactless conductometric determination of methanol and ethanol in samples containing water after their electrophoretic desalination.
abstract: Determination of the contents of methanol and ethanol in aqueous solutions was performed by measuring the permittivity of solutions using a contactless conductivity detector (C(4) D) normally used for detection in capillary electrophoresis. The detection cell is a section of a fused silica capillary with an internal diameter of 50 μm with a pair of conductivity electrodes on the external walls. The C(4) D response to samples of methanol/water and ethanol/water mixtures is linear in the concentration interval of approx. 40-100% v/v alcohol content. In the analysis of technical samples of methanol and ethanol, the determination is disturbed by the presence of even trace amounts of salts. This interference can be effectively eliminated by integrated electrophoretic desalination of the sample by the application of a direct current electric voltage with a magnitude of 10 kV to the capillary with the injected sample zone. Under these conditions, the ions migrate out of the sample zone and the detector response is controlled purely by the permittivity of the solvent/water zone. Desalinating is effective for NaCl contents in the range from 0 to 5 mmol/L NaCl. The effectiveness of the desalinating process has been verified on MeOH/water samples and in determination of the ethanol content in distilled beverages normally available in the retail network.
authors.affiliation: Charles University in Prague, Third Faculty of Medicine, Institute of Biochemistry, Cell and Molecular Biology, Prague, Czech Republic.
authors.forename: Petr
authors.initials: P
authors.lastname: Tůma
authors.affiliation: Charles University in Prague, Faculty of Science, Department of Analytical Chemistry, Prague, Czech Republic.
authors.forename: František
authors.initials: F
authors.lastname: Opekar
mesh_terms: D003217:Conductometry / Q000379:methods*; D019075:Electrophoresis, Capillary / Q000379:methods*; D000431:Ethanol / Q000032:analysis* / Q000737:chemistry; D016014:Linear Models; D000432:Methanol / Q000032:analysis* / Q000737:chemistry; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012965:Sodium Chloride; D014867:Water / Q000737:chemistry
chemical_list: D014867:Water; D000431:Ethanol; D012965:Sodium Chloride; D000432:Methanol
keywords: Capillary electrophoresis; Contactless conductivity detection; Desalination; Organic solvent; Sensors