title: Successful management of severe hyponatraemia during continuous renal replacement therapy.
abstract: Rapid correction of chronic hyponatraemia can lead to osmotic demyelination syndrome. Ensuring a gradual correction can be difficult, especially in patients on renal replacement therapy (RRT). A 43-year-old renal transplant patient presented with severe chronic hyponatraemia. She required continuous RRT. The hyponatraemia was corrected successfully by manually adjusting sodium concentration in the dialysate. Our case describes an effective method to ensure severe hyponatraemia is corrected safely during continuous RRT.
authors.affiliation: Department of Nephrology, Guy's and St Thomas' Hospital, London, UK.
authors.forename: Diana
authors.initials: D
authors.lastname: Vassallo
authors.affiliation: Department of Nephrology, Guy's and St Thomas' Hospital, London, UK.
authors.forename: Denise
authors.initials: D
authors.lastname: Camilleri
authors.affiliation: Department of Nephrology, Guy's and St Thomas' Hospital, London, UK.
authors.forename: Vicki
authors.initials: V
authors.lastname: Moxham
authors.affiliation: Department of Nephrology, Guy's and St Thomas' Hospital, London, UK.
authors.forename: Marlies
authors.initials: M
authors.lastname: Ostermann
keywords: continuous renal replacement therapy; continuous veno-venous haemodialysis; hyponatraemia; osmotic demyelination syndrome