title: Time trends in the etiology of chronic pancreatitis in South India.
abstract: BACKGROUND
  Recent reports indicate a decline in prevalence of classical tropical chronic pancreatitis (TCP). We studied the etiologies and risk factors over a 14-year period at a tertiary care university hospital.
  
  
  METHODS
  We compared the etiology in chronic pancreatitis (CP) patients presenting and followed-up in our Pancreas Clinic over two time periods (2000-06 and 2007-13).
  
  
  RESULTS
  Idiopathic chronic pancreatitis (ICP) was the predominant etiology seen over the two time periods. However an increase in prevalence of alcoholic chronic pancreatitis (ACP) during the latter time period suggests that it may be emerging as a dominant etiology over recent years. Hypertriglyceridemia and hyperparathyroidism were uncommon causes of non-alcoholic CP. Autoimmune pancreatitis was noted only during 2007-13, but remains a rare cause of CP. There are multiple risk factors for CP in our population.
  
  
  CONCLUSIONS
  The high prevalence of ICP indicates need closer examination of risk factors and ICP pathogenesis. ACP appears to be emerging as a dominant cause of CP which suggests a need to reorient preventive strategies.
authors.forename: Gopalakrishna
authors.initials: G
authors.lastname: Rajesh
authors.forename: Banavara Narasimhamurthy
authors.initials: BN
authors.lastname: Girish
authors.forename: Suprabha
authors.initials: S
authors.lastname: Panicker
authors.forename: Vallath
authors.initials: V
authors.lastname: Balakrishnan
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D019512:Pancreatitis, Alcoholic / Q000453:epidemiology / Q000209:etiology; D050500:Pancreatitis, Chronic / Q000453:epidemiology / Q000209:etiology*; D015995:Prevalence; D012307:Risk Factors