title: Dietary vitamin A restriction affects adipocyte differentiation and fatty acid composition of intramuscular fat in Iberian pigs.
abstract: The aim of this study was to investigate whether dietary vitamin A level is associated with differences in adipocyte differentiation or lipid accumulation in Iberian pigs at early growing (35.8kg live weight) and at finishing (158kg live weight). Iberian pigs of 16.3kg live weight were allocated to two feeding groups, one group received 10,000IU of vitamin A/kg diet (control); the other group received a diet with 0IU of vitamin A (var) for the whole experimental period. The dietary vitamin A level had no effect on growth performance and carcass traits. The early suppression of vitamin A increased the preadipocyte number in Longissimus thoracis (LT) muscle in the early growth period (P<0.001) and the neutral lipid content and composition (higher MUFA and lower SFA content) at the end of the finishing period (P<0.05). Vitamin A restriction in young pigs increases their lipogenic potential without affecting carcass traits.
authors.affiliation: Departamento de Producción Animal, Facultad de Veterinaria, Universidad Complutense, 28040 Madrid, Spain. Electronic address: mayuso@ucm.es.
authors.forename: M
authors.initials: M
authors.lastname: Ayuso
authors.affiliation: Departamento de Mejora Genética Animal, INIA, 28040 Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Óvilo
authors.affiliation: Departamento de Medicina y Cirugía, Facultad de Veterinaria, Universidad Complutense, 28040 Madrid, Spain; Animal Health Surveillance Center (VISAVET), Complutense University of Madrid, 28040 Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez-Bertos
authors.affiliation: Departamento de Producción Animal, Facultad de Veterinaria, Universidad Complutense, 28040 Madrid, Spain.
authors.forename: A I
authors.initials: AI
authors.lastname: Rey
authors.affiliation: Departamento de Producción Animal, ETSIA, Universidad Politécnica de Madrid, 28040 Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Daza
authors.affiliation: Departamento de Mejora Genética Animal, INIA, 28040 Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Fenández
authors.affiliation: Departamento de Reproducción Animal, INIA, 28040 Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: González-Bulnes
authors.affiliation: Departamento de Producción Animal, Facultad de Veterinaria, Universidad Complutense, 28040 Madrid, Spain.
authors.forename: C J
authors.initials: CJ
authors.lastname: López-Bote
authors.affiliation: Departamento de Producción Animal, Facultad de Veterinaria, Universidad Complutense, 28040 Madrid, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Isabel
mesh_terms: D017667:Adipocytes / Q000166:cytology*; D000273:Adipose Tissue / Q000737:chemistry*; D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001835:Body Weight; D002454:Cell Differentiation; D004032:Diet / Q000662:veterinary; D015536:Down-Regulation; D005227:Fatty Acids / Q000737:chemistry*; D005229:Fatty Acids, Monounsaturated / Q000737:chemistry; D008460:Meat / Q000032:analysis*; D018482:Muscle, Skeletal / Q000737:chemistry*; D018168:Receptors, Retinoic Acid / Q000235:genetics / Q000378:metabolism; D013552:Swine; D014801:Vitamin A / Q000008:administration & dosage*
chemical_list: D005227:Fatty Acids; D005229:Fatty Acids, Monounsaturated; D018168:Receptors, Retinoic Acid; C082928:retinoic acid binding protein II, cellular; D014801:Vitamin A
keywords: Fatty acid; Iberian pig; Intramuscular fat; Preadipocyte; Vitamin A