title: Subcutaneous infection caused by Blastoschizomyces capitatus post allogeneic hematopoietic transplant and its successful treatment with voriconazole.
abstract: We describe a 33-year-old man with relapsed acute myelogenous leukemia who developed subcutaneous nodules >6 months after allogeneic hematopoietic stem cell transplant. These nodules were caused by Blastoschizomyces capitatus. The lesions progressed after treatment with a posaconazole suspension. The lesions resolved after switching to voriconazole, which was given for 21 weeks. B. capitatus is a rare infection affecting immunocompromised patients, which responds to azoles.
authors.affiliation: Medical Oncology, Tata Memorial Center, Mumbai, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Devadas
authors.affiliation: Medical Oncology, Tata Memorial Center, Mumbai, India.
authors.forename: V
authors.initials: V
authors.lastname: Bhat
authors.affiliation: Medical Oncology, Tata Memorial Center, Mumbai, India.
authors.forename: N
authors.initials: N
authors.lastname: Khattry
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D003881:Dermatomycoses / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D055157:Dipodascus / Q000302:isolation & purification*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000628:therapy*; D008297:Male; D009894:Opportunistic Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D065819:Voriconazole / Q000627:therapeutic use*
chemical_list: D000935:Antifungal Agents; D065819:Voriconazole
keywords: Blastoschizomyces capitatus; hematopoietic transplant; rare fungal infection; voriconazole