title: Manadodioxans A-E: polyketide endoperoxides from the marine sponge Plakortis bergquistae.
abstract: Five new polyketide endoperoxides, manadodioxans A-E, were isolated from the marine sponge Plakortis bergquistae. Manadodioxan E showed antimicrobial activity against Escherichia coli at 10 μg/disk, while its oxo congener, manadodioxan D, was inactive.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, 862-0973, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Gushiken
authors.forename: Ippei
authors.initials: I
authors.lastname: Kagiyama
authors.forename: Hikaru
authors.initials: H
authors.lastname: Kato
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Kuwana
authors.forename: Fitje
authors.initials: F
authors.lastname: Losung
authors.forename: Remy E P
authors.initials: RE
authors.lastname: Mangindaan
authors.forename: Nicole J
authors.initials: NJ
authors.lastname: de Voogd
authors.forename: Sachiko
authors.initials: S
authors.lastname: Tsukamoto
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry*; D047229:Plakortis / Q000737:chemistry*; D010946:Plants, Medicinal; D061065:Polyketides / Q000737:chemistry*; D011161:Porifera / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D061065:Polyketides