title: [Maternal and fetal outcome in Mexican women with rheumatoid arthritis].
abstract: OBJECTIVE
  To report our experience in maternal-fetal outcome in women with RA in a national medical referral center.
  
  
  METHODS
  A retrospective analysis of the records of pregnant women with rheumatoid arthritis attending at a Pregnancy and Autoimmune Rheumatic Diseases Clinic was performed. Maternal-fetal outcomes such as disease activity, preclampsia/eclampsia, rate of live births, abortions, stillbirths, preterm birth, weeks of gestation, birth weight, congenital malformations and use of anti-rheumatic drugs were studied.
  
  
  RESULTS
  We included 73 pregnancies in 72 patients. Disease activity was documented in 47.2% of patients during pregnancy and/or postpartum and 87.7% of patients received some antirheumatic drug. Preclampsia developed in 8.2% of cases. The live birth rate was 98.6%, with preterm delivery in 15.9% and low weight at term in 17.6% of cases. Cesarean section was performed in 77.1% of cases. The disease activity was not associated with a higher percentage of maternal-fetal complications.
  
  
  CONCLUSIONS
  Our study showed that most patients do not experience significant activity of RA during pregnancy, fetal outcome is satisfactory and disease activity did not appear to influence significantly the obstetric outcome.
authors.affiliation: Departamento de Reumatología, Hospital de Especialidades, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Distrito Federal. miansaavsa@gmail.com.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Saavedra
authors.forename: Antonio
authors.initials: A
authors.lastname: Sánchez
authors.forename: Reyna
authors.initials: R
authors.lastname: Bustamante
authors.forename: Dafhne
authors.initials: D
authors.lastname: Miranda-Hernández
authors.forename: Jimena
authors.initials: J
authors.lastname: Soliz-Antezana
authors.forename: Pilar
authors.initials: P
authors.lastname: Cruz-Domínguez
authors.forename: Sara
authors.initials: S
authors.lastname: Morales
authors.forename: Luis J
authors.initials: LJ
authors.lastname: Jara
mesh_terms: D000022:Abortion, Spontaneous / Q000453:epidemiology / Q000209:etiology; D000328:Adult; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D002585:Cesarean Section / Q000706:statistics & numerical data; D000013:Congenital Abnormalities / Q000453:epidemiology / Q000209:etiology; D005260:Female; D005317:Fetal Growth Retardation / Q000453:epidemiology / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008800:Mexico; D011225:Pre-Eclampsia / Q000453:epidemiology / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D050497:Stillbirth / Q000453:epidemiology
chemical_list: D018501:Antirheumatic Agents
keywords: Preclampsia; Pregnancy; Rheumatoid arthritis