title: Simultaneous Nano- and Microscale Control of Nanofibrous Microspheres Self-Assembled from Star-Shaped Polymers.
abstract: Star-shaped polymers with varying arm numbers and arm lengths are synthesized, and self-assembled into microspheres, which are either smooth or fibrous on the nanoscale, and either nonhollow, hollow, or spongy on the microscale. The molecular architecture and functional groups determine the structure on both length scales. This exciting mechanistic discovery guides simultaneous control of both the nano- and microfeatures of the microspheres.
authors.affiliation: Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109-1078, USA.
authors.forename: Zhanpeng
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Materials Science and Engineering, University of Michigan, Ann Arbor, MI, 48109-1078, USA.|Biointerfaces Institute, University of Michigan, Ann Arbor, MI, 48109-1078, USA.
authors.forename: Ryan L
authors.initials: RL
authors.lastname: Marson
authors.affiliation: Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI, 48109-1078, USA.
authors.forename: Zhishen
authors.initials: Z
authors.lastname: Ge
authors.affiliation: Materials Science and Engineering, University of Michigan, Ann Arbor, MI, 48109-1078, USA.|Biointerfaces Institute, University of Michigan, Ann Arbor, MI, 48109-1078, USA.|Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, 48109-1078, USA.|Macromolecular Science and Engineering Center, University of Michigan, Ann Arbor, MI, 48109-1078, USA.
authors.forename: Sharon C
authors.initials: SC
authors.lastname: Glotzer
authors.affiliation: Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109-1078, USA.|Materials Science and Engineering, University of Michigan, Ann Arbor, MI, 48109-1078, USA.|Biointerfaces Institute, University of Michigan, Ann Arbor, MI, 48109-1078, USA.|Department of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI, 48109-1078, USA.|Macromolecular Science and Engineering Center, University of Michigan, Ann Arbor, MI, 48109-1078, USA.
authors.forename: Peter X
authors.initials: PX
authors.lastname: Ma
mesh_terms: D019344:Lactic Acid / Q000737:chemistry*; D008863:Microspheres; D008958:Models, Molecular; D008968:Molecular Conformation; D057139:Nanofibers / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D011091:Polyesters; D011108:Polymers / Q000737:chemistry*
chemical_list: D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide)
keywords: biomaterials; nanofibrous microspheres; self-assembly; simulations; star-shaped polymers