title: Photo-cross-linking using trifluorothymidine and 3-cyanovinylcarbazole induced a large shifted (19)F MR signal.
abstract: Photo-cross-linking of trifluorothymidine ((TF)T) using 3-cyanovinylcarbazole ((CNV)K) clearly shifted its (19)F nuclear magnetic resonance (NMR) signal 8 ppm. This (CNV)K mediated ultrafast photo-cross-linking-induced shift can be utilized for miRNA detection by hybridization chain reaction (HCR) to detect 10 nM of a target in a sequence-specific manner.
authors.affiliation: Materials Science and Technology, Japan Advanced Institute of Science and Technology, 1-1 Asahi-dai, Nomi, Ishikawa 923-1292, Japan. kenzo@jaist.ac.jp.
authors.forename: Shigetaka
authors.initials: S
authors.lastname: Nakamura
authors.forename: Kenzo
authors.initials: K
authors.lastname: Fujimoto
mesh_terms: D002227:Carbazoles / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D035683:MicroRNAs / Q000032:analysis; D015394:Molecular Structure; D055668:Photochemical Processes; D014271:Trifluridine / Q000737:chemistry*
chemical_list: D002227:Carbazoles; D003432:Cross-Linking Reagents; D035683:MicroRNAs; D005461:Fluorine; D014271:Trifluridine