title: Iodine-catalyzed sp³ C-H bond activation by selenium dioxide: synthesis of diindolylmethanes and di(3-indolyl)selanides.
abstract: An efficient reaction protocol was developed for the synthesis of several diindolylmethane derivatives via the [Formula: see text] C-H bond activation of aryl methyl ketones by [Formula: see text] and indoles in the presence of catalytic amounts of [Formula: see text] at 80 [Formula: see text] using dioxane as solvent. Unexpectedly, an interesting class of di(3-indolyl)selenide compounds was isolated when the reaction was carried out at room temperature.
authors.affiliation: Medicinal Chemistry Division, CSIR-North East Institute of Science & Technology, Jorhat, 785006, Assam, India.
authors.forename: P Seetham
authors.initials: PS
authors.lastname: Naidu
authors.affiliation: Medicinal Chemistry Division, CSIR-North East Institute of Science & Technology, Jorhat, 785006, Assam, India.
authors.forename: Swarup
authors.initials: S
authors.lastname: Majumder
authors.affiliation: Medicinal Chemistry Division, CSIR-North East Institute of Science & Technology, Jorhat, 785006, Assam, India. pulak_jyoti@yahoo.com.
authors.forename: Pulak J
authors.initials: PJ
authors.lastname: Bhuyan
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D007454:Iodides / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D064588:Selenium Oxides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007211:Indoles; D007454:Iodides; D064588:Selenium Oxides; D007455:Iodine; C016392:3,3'-diindolylmethane
keywords: C–H activation; Diindolylmethanes; Indole; Indolylselanides; Iodine; Selanides