title: Does Diabetes Have an Influence on Regional Deformation Parameters in Patients with Normal Systolic Function during Off-Pump Coronary Artery Bypass Grafting?
abstract: OBJECTIVE
  The aim of this study was to assess the recovery of regional myocardial function of the left-ventricular septal wall and the septal site of the mitral valve (MV) annulus by tissue Doppler imaging (TDI).
  
  
  METHODS
  In 63 (32 diabetic and 31 control) patients having off-pump coronary artery bypass grafting (OPCABG), including the left internal mammary artery (LIMA) and the left anterior descending coronary artery (LAD), TDI measurements were performed before operation (baseline), 5 min after LIMA-LAD revascularization (early reperfusion) and after completion of all anastomoses (after revascularization).
  
  
  RESULTS
  Compared to the patients with diabetes, the controls had higher peak systolic velocities of the mid septal segments in the early reperfusion measurement (p = 0.002). After revascularization, values of peak systolic strain at the basal (-10.13 vs. -13.36%, p = 0.044) and mid septal segments (-8.25 vs. -12.69%, p = 0.009) were decreased in the diabetic patients compared to the controls. There was no difference between the groups with respect to the velocities acquired at the septal site of the MV annulus.
  
  
  CONCLUSIONS
  This study demonstrates an insufficient recovery of regional myocardial function in patients with type II diabetes undergoing OPCABG.
authors.affiliation: Department of Medicine, Medikol Polyclinic, Zagreb, Croatia.
authors.forename: Ana
authors.initials: A
authors.lastname: Barisin
authors.forename: Zdenko
authors.initials: Z
authors.lastname: Sonicki
authors.forename: Josip
authors.initials: J
authors.lastname: Vincelj
authors.forename: Zeljko
authors.initials: Z
authors.lastname: Sutlic
authors.forename: Stjepan
authors.initials: S
authors.lastname: Barisin
mesh_terms: D000368:Aged; D047549:Coronary Artery Bypass, Off-Pump / Q000379:methods*; D003331:Coronary Vessels / Q000000981:diagnostic imaging; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D015150:Echocardiography, Doppler / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008323:Mammary Arteries / Q000000981:diagnostic imaging; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging; D013599:Systole / Q000502:physiology