title: Neuropsychological markers of mild cognitive impairment: A clinic based study from urban India.
abstract: BACKGROUND
  Mild cognitive impairment (MCI) is a transitional stage between normal aging and dementia. Persons with MCI are at higher risk to develop dementia. Identifying MCI from normal aging has become a priority area of research. Neuropsychological assessment could help to identify these high risk individuals.
  
  
  OBJECTIVE
  To examine clinical utility and diagnostic accuracy of neuropsychological measures in identifying MCI.
  
  
  METHODS
  This is a cross-sectional study of 42 participants (22 patients with MCI and 20 normal controls [NC]) between the age of 60 and 80 years. All participants were screened for dementia and later a detailed neuropsychological assessment was carried out.
  
  
  RESULTS
  Persons with MCI performed significantly poorer than NC on word list (immediate and delayed recall), story recall test, stick construction delayed recall, fluency and Go/No-Go test. Measures of episodic memory especially word list delayed recall had the highest discriminating power compared with measures of semantic memory and executive functioning.
  
  
  CONCLUSIONS
  Word list learning with delayed recall component is a possible candidate for detecting MCI from normal aging.
authors.affiliation: Department of Psychology, Narayana Health, Mazumdar Shaw Medical Centre, Bangalore, India.
authors.forename: Ravikesh
authors.initials: R
authors.lastname: Tripathi
authors.affiliation: Department of Clinical Psychology, NIMHANS, Bangalore, Karnataka, India.
authors.forename: Keshav
authors.initials: K
authors.lastname: Kumar
authors.affiliation: Department of Psychiatry, NIMHANS, Bangalore, Karnataka, India.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Balachandar
authors.affiliation: Department of Biostatistics and Psychiatry, NIMHANS, Bangalore, Karnataka, India.
authors.forename: P
authors.initials: P
authors.lastname: Marimuthu
authors.affiliation: Department of Psychiatry, NIMHANS, Bangalore, Karnataka, India.
authors.forename: Mathew
authors.initials: M
authors.lastname: Varghese
authors.affiliation: Department of Psychiatry, NIMHANS, Bangalore, Karnataka, India.
authors.forename: Srikala
authors.initials: S
authors.lastname: Bharath
keywords: Cognitive marker; cognitive test; memory assessment; mild cognitive impairment