title: A feasibility study of a rotary planar electrode array for electrical impedance mammography using a digital breast phantom.
abstract: A feasibility study of an electrical impedance mammography (EIM) system with a rotary planar electrode array, named RPEIM, is presented. The RPEIM system is an evolution of the Sussex MK4 system, which is a prototype instrument for breast cancer detection. Comparing it with the other planar electrode EIM systems, the rotation feature enables a dramatic increase in the number of independent measurements. To assist impedance evaluation exploiting electrode array rotation, a synchronous mesh method is proposed. Using the synchronous mesh method, the RPEIM system is shown to have superior performance in image accuracy, spatial resolution and noise tolerance over the MK4 system. To validate the study, we report simulations based on a close-to-realistic 3D digital breast phantom, which comprises of: skin, nipple, ducts, acinus, fat and tumor. A digital breast phantom of a real patient is constructed, whose tumor was detected using the MK4 system. The reconstructed conductivity image of the breast phantom indicates that the breast phantom is a close replica of the patient's real breast as assessed by the MK4 system in a clinical trial. A comparison between the RPEIM system and the MK4 system is made based on this phantom to assess the advantages of the RPEIM system.
authors.affiliation: Department of Engineering, University of Sussex, Brighton BN1 9QT, UK.
authors.forename: X
authors.initials: X
authors.lastname: Zhang
authors.forename: C
authors.initials: C
authors.lastname: Chatwin
authors.forename: D C
authors.initials: DC
authors.lastname: Barber
mesh_terms: D001940:Breast; D017097:Electric Impedance; D004566:Electrodes; D005240:Feasibility Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008327:Mammography / Q000295:instrumentation*; D019047:Phantoms, Imaging; D012399:Rotation; D059629:Signal-To-Noise Ratio