title: Diterpenes and lignans from Viburnum odoratissimum var. odoratissimum.
abstract: A new diterpenoid, dehydrovibsanin G (1), a new lignan, (+)-9'-O-senecioyllariciresinol (2), and six known compounds (3-8) were isolated from the branches and leaves of Viburnum odoratissimum var. odoratissimum. The structures of these compounds were elucidated by analysis of spectroscopic data. Both new compounds showed moderate inhibitory activity against human A431 and T47D tumor cell lines.
authors.affiliation: a State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , Shanghai 201203 , China.
authors.forename: Feng-Jie
authors.initials: FJ
authors.lastname: Li
authors.forename: Jin-Hai
authors.initials: JH
authors.lastname: Yu
authors.forename: Guo-Cai
authors.initials: GC
authors.lastname: Wang
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.forename: Jian-Min
authors.initials: JM
authors.lastname: Yue
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D018515:Plant Leaves / Q000737:chemistry; D027925:Viburnum / Q000737:chemistry*
chemical_list: C000601434:9'-O-senecioyllariciresinol; D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; D017705:Lignans; C000601433:dehydrovibsanin G
keywords: Caprifoliaceae; Viburnum odoratissimum var. odoratissimum; cytotoxicity; diterpenoid; lignan