title: [Comparison of symptoms, laboratory parameters and illness perception in patients with irritable bowel syndrome and inflammatory bowel disease].
abstract: BACKGROUND
  Symptoms-based differential diagnosis of irritable bowel syndrome and inflammatory bowel disease is often difficult.
  
  
  OBJECTIVE
  To determine the differential diagnostic ability of clinical activity indexes and psychological questionnaires in these conditions, which have never been simultaneously analyzed.
  
  
  METHODS
  37 irritable bowel syndrome, 54 Crohn's disease and 41 ulcerative colitis patients were enrolled in the study. The patients completed the Crohn's Disease Activity Index test, Illness Perception Questionnaire and Inflammatory Bowel Disease Questionnaire. Hematocrit and C-reactive protein level of patients were also analyzed.
  
  
  RESULTS
  Patients with irritable bowel syndrome felt their abdominal pain more severe than the other two groups (p = 0.005), while the quality of life was the worst in Crohn's disease (p = 0.0000001). Significantly more patients with inflammatory bowel disease considered that their condition is lifelong (p = 0.000781). The knowledge about disease was more appropriate in patients with inflammatory bowel disease (p = 0.00629). No significant difference was found in hematocrit levels, but the C-reactive protein level was significantly lower in patients with irritable bowel syndrome (p = 0.001).
  
  
  CONCLUSIONS
  Illness perception questionnaires and C-reactive protein can help in the differentiation of inflammatory bowel disease from irritable bowel syndrome.
authors.affiliation: I. Belgyógyászati Klinika, Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged, Korányi fasor 8-10., 6720.
authors.forename: Renáta
authors.initials: R
authors.lastname: Bor
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Balanyi
authors.forename: Klaudia
authors.initials: K
authors.lastname: Farkas
authors.forename: Anita
authors.initials: A
authors.lastname: Bálint
authors.forename: Mariann
authors.initials: M
authors.lastname: Rutka
authors.forename: Mónika
authors.initials: M
authors.lastname: Szűcs
authors.forename: Ágnes
authors.initials: Á
authors.lastname: Milassin
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Szepes
authors.forename: Ferenc
authors.initials: F
authors.lastname: Nagy
authors.forename: Tamás
authors.initials: T
authors.lastname: Molnár
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D001828:Body Image; D002097:C-Reactive Protein / Q000378:metabolism*; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000523:psychology; D003424:Crohn Disease / Q000175:diagnosis / Q000523:psychology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000523:psychology*; D043183:Irritable Bowel Syndrome / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D010465:Perception; D011788:Quality of Life; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein
keywords: C-reactive protein; C-reaktív protein; gyulladásos bélbetegség; inflammatory bowel disease; irritable bowel syndrome; irritábilis bél szindróma; life quality questionnaire; életminőség-kérdőív