title: Acute paraplegia in a preterm infant with cerebral sinovenous thrombosis.
abstract: We report the case of a 1-month old, 28-week gestational age infant who presented with acute paraplegia after cardiopulmonary arrest. Later imaging confirms cerebral sinovenous thrombosis (CSVT) and a suspected infarction in the conus medullaris of the spinal cord. A prothrombotic state may explain the numerous areas of infarction visualized on neuroimaging. To our knowledge this is the first case report of acute and persistent paraplegia in an infant with CSVT and conus medullaris injury, which may be due to venous infarction of the spinal cord.
authors.affiliation: Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: J
authors.initials: J
authors.lastname: Hobbs
authors.affiliation: 1] Department of Pediatric Neuroradiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA [2] Neurosciences Intensive Care Nursery, Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: A
authors.initials: A
authors.lastname: Tekes
authors.affiliation: 1] Neurosciences Intensive Care Nursery, Johns Hopkins Hospital, Baltimore, MD, USA [2] Department of Neurology, Pediatric Stroke Program Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: J
authors.initials: J
authors.lastname: Klein
authors.affiliation: 1] Neurosciences Intensive Care Nursery, Johns Hopkins Hospital, Baltimore, MD, USA [2] Department of Neurology, Pediatric Stroke Program Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: M
authors.initials: M
authors.lastname: Lemmon
authors.affiliation: 1] Neurosciences Intensive Care Nursery, Johns Hopkins Hospital, Baltimore, MD, USA [2] Department of Neurology, Pediatric Stroke Program Johns Hopkins University School of Medicine, Baltimore, MD, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Felling
authors.affiliation: 1] Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA [2] Neurosciences Intensive Care Nursery, Johns Hopkins Hospital, Baltimore, MD, USA.
authors.forename: R
authors.initials: R
authors.lastname: Chavez-Valdez
mesh_terms: D006323:Heart Arrest; D006801:Humans; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D007238:Infarction / Q000150:complications; D008279:Magnetic Resonance Imaging; D010264:Paraplegia / Q000209:etiology*; D012851:Sinus Thrombosis, Intracranial / Q000150:complications*; D013116:Spinal Cord / Q000098:blood supply