title: Carcinosarcoma of the uterine cervix arising from Müllerian ducts.
abstract: Carcinosarcomas of the uterine cervix are extremely rare. Cervical carcinosarcoma can be characterized by having two different origins: the Müllerian ducts and the mesonephric duct remnants. A 53-year-old Korean woman was admitted to the hospital because of pelvic mass detected on computed tomography scan done at private clinic. A Radical hysterectomy with bilateral salpingooophorectomy and pelvic lymphadenectomy was carried out upon a diagnosis of stage IB2 cervical sarcoma. Immunohistochemically, the epithelial component was positive for pancytokeratin and estrogen receptor, but negative for CD 10 and carletinin. The mesenchymal component was positive for vimentin. The histopathologic diagnosis was a carcinosarcoma of the uterine cervix arising from Müllerian ducts. She underwent chemotherapy. She developed systemic recurrence seven months after operation and died of disease. The origin of cervical carcinosarcoma needs to be verified and immunohistochemical studies using mesonephric marker (CD 10, carletinin, and estrogen receptor) is helpful.
authors.affiliation: Department of Obstetrics and Gynecology, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, Korea.
authors.forename: Myounghwan
authors.initials: M
authors.lastname: Kim
authors.affiliation: Department of Obstetrics and Gynecology, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, Korea.
authors.forename: Chulmin
authors.initials: C
authors.lastname: Lee
authors.affiliation: Department of Obstetrics and Gynecology, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, Korea.
authors.forename: Hoon
authors.initials: H
authors.lastname: Choi
authors.affiliation: Department of Obstetrics and Gynecology, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, Korea.
authors.forename: Ji-Kyung
authors.initials: JK
authors.lastname: Ko
authors.affiliation: Department of Pathology, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, Korea.
authors.forename: Guhyun
authors.initials: G
authors.lastname: Kang
authors.affiliation: Department of Obstetrics and Gynecology, Ilsan Paik Hospital, Inje University School of Medicine, Goyang, Korea.
authors.forename: Kyoung-Chul
authors.initials: KC
authors.lastname: Chun
keywords: Breast neoplasms; Carcinosarcoma; Cervix uteri; Müllerian duct; Müllerian tumor mixed