title: Two cases of extrapulmonary onset granulomatosis with polyangiitis which caused diffuse alveolar haemorrhage.
abstract: Granulomatosis with polyangiitis (GPA) is a rare form of vasculitis. Multidisciplinary therapeutic approach and early diagnosis assume vital importance in management of patients with diffuse alveolar haemorrhage caused by GPA, which is a rare complication. The purpose of this study was to present the diagnostic and therapeutic challenges experienced by clinicians in management of two severe cases of GPA with insidious extrapulmonary manifestations which rapidly progressed into acute kidney injury, alveolar haemorrhage and acute respiratory failure.
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Halide
authors.initials: H
authors.lastname: Kaya
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Sureyya
authors.initials: S
authors.lastname: Yilmaz
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Cengizhan
authors.initials: C
authors.lastname: Sezgi
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Abakay
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Mahsuk
authors.initials: M
authors.lastname: Taylan
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Hadice
authors.initials: H
authors.lastname: Sen
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Melike
authors.initials: M
authors.lastname: Demir
authors.affiliation: Department of Dermatology, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Zeynep Meltem
authors.initials: ZM
authors.lastname: Akkurt
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Dicle University, Diyarbakir 21280, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Senyigit
keywords: Acute respiratory failure; Diffuse alveolar haemorrhage; Extrapulmonary findings; Granulomatosis with polyangiitis