title: Plants and their bioactive compounds with the potential to enhance mechanisms of inherited cardiac regeneration.
abstract: This article reviews the current progress and research indications in the application of natural plant compounds with the potential for the treatment of cardiovascular diseases. Our understanding of how to apply natural plant compounds to enhance mechanisms of inherited cardiac regeneration, which is physiologically pertinent to myocyte turnover or minor cardiac repair, for substantial cardiac regeneration to repair pathological heart injuries is discussed. Although significant progress has been made in the application of natural plant compounds for therapy of heart diseases, the understanding or the application of these compounds specifically for enhancing mechanisms of inherited cardiac regeneration for the treatment of cardiovascular diseases is little. Recent recognition of some natural plant compounds that can repair damaged myocardial tissues through enhancing mechanisms of inherited cardiac regeneration has offered an alternative for clinical translation. Application of natural plant compounds, which show the activity of manipulating gene expressions in such a way to enhance mechanisms of inherited cardiac regeneration for cardiac repair, may provide a promising strategy for the reconstruction of damaged cardiac tissues due to cardiovascular diseases.
authors.affiliation: Laboratory of Innovative Medicine, Hong Kong.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhou
authors.affiliation: Emergency Department, Tianshan Chinese Medicine Hospital, Shanghai, China.
authors.forename: Dianbin
authors.initials: D
authors.lastname: Li
authors.affiliation: Department of Cardiology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhou
authors.affiliation: Laboratory of Innovative Medicine, Hong Kong.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Lin
authors.affiliation: Queen Mary University of London, London, UK.
authors.forename: Censing
authors.initials: C
authors.lastname: Li
authors.affiliation: Laboratory of Innovative Medicine, Hong Kong.
authors.forename: Mingfeng
authors.initials: M
authors.lastname: Tang
authors.affiliation: Department of Cardiology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
authors.forename: Zhou
authors.initials: Z
authors.lastname: Feng
authors.affiliation: Laboratory of Innovative Medicine, Hong Kong.
authors.forename: Ming
authors.initials: M
authors.lastname: Li
mesh_terms: D001688:Biological Products / Q000627:therapeutic use*; D002318:Cardiovascular Diseases / Q000188:drug therapy*; D002454:Cell Differentiation / Q000187:drug effects; D006801:Humans; D010944:Plants / Q000737:chemistry*; D012038:Regeneration / Q000187:drug effects*
chemical_list: D001688:Biological Products