title: Adverse Pregnancy Conditions, Infertility, and Future Cardiovascular Risk: Implications for Mother and Child.
abstract: Adverse pregnancy conditions in women are common and have been associated with adverse cardiovascular and metabolic outcomes such as myocardial infarction and stroke. As risk stratification in women is often suboptimal, recognition of non-traditional risk factors such as hypertensive disorders of pregnancy and premature delivery has become increasingly important. Additionally, such conditions may also increase the risk of cardiovascular disease in the children of afflicted women. In this review, we aim to highlight these conditions, along with infertility, and the association between such conditions and various cardiovascular outcomes and related maternal risk along with potential translation of risk to offspring. We will also discuss proposed mechanisms driving these associations as well as potential opportunities for screening and risk modification.
authors.affiliation: Division of Cardiovascular Medicine, University of Florida, 1600 SW Archer Rd, P.O. Box 100277, Gainesville, FL, 32610-0277, USA.
authors.forename: Ki
authors.initials: K
authors.lastname: Park
authors.forename: Janet
authors.initials: J
authors.lastname: Wei
authors.forename: Margo
authors.initials: M
authors.lastname: Minissian
authors.forename: C Noel
authors.initials: CN
authors.lastname: Bairey Merz
authors.forename: Carl J
authors.initials: CJ
authors.lastname: Pepine
mesh_terms: D002318:Cardiovascular Diseases / Q000453:epidemiology*; D002648:Child; D005260:Female; D006801:Humans; D007246:Infertility; D009035:Mothers; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D012307:Risk Factors