title: [Featuring pathogenicity factors in biofilm-forming and no-biofilm forming strains of Staphylococcus epidermidis].
abstract: A comparative study of the manifestation of pathogenicity factors: hemolytic, lipase, letsytinase activity and ability to adhere in 20 film-forming and 17 non-film-forming strains of S. epidermidis. Studying pathogenicity factors of the film-forming strains it was found that complete hemolysis and lipase activity shown was by all the film-forming strains of S. epidermidis, letsytinase activity was observed in 80%. Among the non-film-forming strains complete hemolysis and lipase activity were observed in 89% and letsytinase - 71%. Researched non-film-forming and film-forming strains of S. epidermidis showed the ability to adhere to buccal epithelial cells of humans. Found that all the film-forming strains of S. epidermidis were hight level adgesion, the highest IAM was equal to 11,84. It was found that among non-film-forming strains of S. epidermidis were low-, medium- and hight level adgesion. IAM of non-film-forming strains of S. epidermidis is 3 times lower compared to the IAM of the film-forming strains of human epithelial cells and was 3.2.
authors.forename: O I
authors.initials: OI
authors.lastname: Sidashenko
authors.forename: O S
authors.initials: OS
authors.lastname: Voronkova
authors.forename: O A
authors.initials: OA
authors.lastname: Sirokvasha
authors.forename: A I
authors.initials: AI
authors.lastname: Vinnikov
mesh_terms: D001422:Bacterial Adhesion; D001426:Bacterial Proteins / Q000378:metabolism*; D018441:Biofilms / Q000254:growth & development*; D002478:Cells, Cultured; D004847:Epithelial Cells / Q000382:microbiology; D006460:Hemolysin Proteins / Q000378:metabolism; D006801:Humans; D008049:Lipase / Q000378:metabolism; D009061:Mouth Mucosa / Q000382:microbiology; D010740:Phospholipases / Q000378:metabolism; D013212:Staphylococcus epidermidis / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism* / Q000472:pathogenicity*; D037521:Virulence Factors / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D006460:Hemolysin Proteins; D037521:Virulence Factors; D010740:Phospholipases; D008049:Lipase