title: Postoperative functional result and quality of life after oesophageal reconstruction based on the type of cervical anastomosis.
abstract: BACKGROUND
  The keystone of the rate of postoperative complications and functional outcome in oesophageal reconstruction is the technique method of performing cervical anastomosis.Despite new technologies and improved technique in specialized centres, post-anastomosis complications have not significantly improved.
  
  
  OBJECTIVE
  The goal of our study is to analyse the causes that make anastomosis with the oesophagus hypopharynx a particular case. If anatomical and morphological aspects cannot be adjusted (poor histological structure and vascularity etc.), some important elements for performing a good anastomosis can be identified and corrected.
  
  
  METHODS
  Between 1981-2014, 195 oesophageal reconstructions were performed in our clinic. Our study involved an analysis of 72 cases (2000-2014), based on a statistical evaluation by Kaplan-Meier method that considered as eries of factors (oesophagus hypopharynx as anastomotic partner, stomach, jejuno-ileum, colon as visceral partner,pharyngotomy type, T-L, T-T, L-L, L-T type anastomosis,number of anastomotic layers). RESULTS were compared with those obtained by standard clinical and laboratory investigation,analysing the post-therapeutic outcome using three criteria (clinical aspects of swallowing, barium swallow and endoscopy) and by subjective assessment by each patient of his her state and complaints, with effects on long-term functional outcome (dysphagia, reflux, pain, asthenia, weight loss, hoarseness).
  
  
  RESULTS
  Statistical analysis determined that only some of the analysed factors proved to be valuable. The higher the level of the anastomosis, the more intense the impairment of the digestive function. The jejunum and left colon proved to bemost effective anastomotic partners. The best method for implantation seems to be T-T or T-L and the number of anastomosis layers has no influence on postoperative outcome.
  
  
  CONCLUSIONS
  Acquired data can influence to some extent the operatory technique, with a lower complication rate.Unfortunately, laborious technical aspects and specific anatomical limitations make this goal difficult to achieve.
authors.forename: I
authors.initials: I
authors.lastname: Predescu
authors.forename: D
authors.initials: D
authors.lastname: Predescu
authors.forename: S
authors.initials: S
authors.lastname: Constantinoiu
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D003106:Colon / Q000637:transplantation; D003679:Deglutition; D004938:Esophageal Neoplasms / Q000601:surgery; D004940:Esophageal Stenosis / Q000601:surgery; D016629:Esophagectomy; D004944:Esophagoplasty / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D004947:Esophagus / Q000601:surgery*; D006801:Humans; D007013:Hypopharynx / Q000601:surgery*; D007082:Ileum / Q000637:transplantation; D007583:Jejunum / Q000637:transplantation; D053208:Kaplan-Meier Estimate; D011788:Quality of Life; D012189:Retrospective Studies; D013270:Stomach / Q000637:transplantation; D011795:Surveys and Questionnaires; D016896:Treatment Outcome