title: Synthesis of New Benzocyclotrimer Analogues: New Receptors for Tetramethylammonium Ion Recognition.
abstract: Using a [2 + 2 + 2] cycloaddition/Mitsunobu reaction sequence, a convenient synthesis to access new benzocyclotrimer analogues has been developed. The new receptors have the geometry and functionality capable of recognizing the tetramethylammonium ion in the gas phase and in solution.
authors.affiliation: †Departamento de Química Orgánica, Instituto Universitario de Bio-Orgánica "Antonio González" (IUBO), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna. Avda. Astrofísico Fco. Sánchez 2, 38200 - La Laguna, S/C. de Tenerife, Spain.
authors.forename: Romen
authors.initials: R
authors.lastname: Carrillo
authors.affiliation: ‡School of Chemistry, National University of Ireland, University Road, Galway, Ireland.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Hynes
authors.affiliation: †Departamento de Química Orgánica, Instituto Universitario de Bio-Orgánica "Antonio González" (IUBO), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna. Avda. Astrofísico Fco. Sánchez 2, 38200 - La Laguna, S/C. de Tenerife, Spain.
authors.forename: Víctor S
authors.initials: VS
authors.lastname: Martín
authors.affiliation: †Departamento de Química Orgánica, Instituto Universitario de Bio-Orgánica "Antonio González" (IUBO), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna. Avda. Astrofísico Fco. Sánchez 2, 38200 - La Laguna, S/C. de Tenerife, Spain.|§Instituto de Productos Naturales y Agrobiología, CSIC Avda. Astrofísico Fco. Sánchez, 3, 38206 La Laguna, S/C. de Tenerife, Spain.
authors.forename: Tomás
authors.initials: T
authors.lastname: Martín
authors.affiliation: †Departamento de Química Orgánica, Instituto Universitario de Bio-Orgánica "Antonio González" (IUBO), Centro de Investigaciones Biomédicas de Canarias (CIBICAN), Universidad de La Laguna. Avda. Astrofísico Fco. Sánchez 2, 38200 - La Laguna, S/C. de Tenerife, Spain.
authors.forename: Fernando Pinacho
authors.initials: FP
authors.lastname: Crisóstomo
mesh_terms: D001584:Benzoxepins / Q000138:chemical synthesis / Q000737:chemistry*; D003500:Cyclization; D007477:Ions / Q000032:analysis; D008958:Models, Molecular; D015394:Molecular Structure; D000644:Quaternary Ammonium Compounds / Q000032:analysis*
chemical_list: D001584:Benzoxepins; D007477:Ions; D000644:Quaternary Ammonium Compounds; C027917:tetramethylammonium