title: Non-melanoma Skin Cancer in Canada Chapter 1: Introduction to the Guidelines.
abstract: BACKGROUND
  Non-melanoma skin cancer (NMSC), including basal and squamous cell carcinoma, represents the most common malignancy.
  
  
  OBJECTIVE
  The aim of this document is to provide guidance to Canadian health care practitioners on NMSC management.
  
  
  METHODS
  After conducting a literature review, the group developed recommendations for prevention, management, and treatment of basal cell carcinomas, squamous cell carcinomas, and actinic keratoses. These tumour types are considered separately in the accompanying articles. The Grading of Recommendations Assessment, Development and Evaluation system was used to assign strength to each recommendation.
  
  
  RESULTS
  This introduction describes the scope and structure of the guidelines and the methods used to develop them. The epidemiology of NMSC is reviewed, as are the pathophysiologic changes occurring with damage to the skin, which lead to the formation of actinic keratoses and invasive squamous or basal cell carcinomas.
  
  
  CONCLUSIONS
  This introduction describes the need for primary prevention and offers an overview of treatment options that are discussed in later chapters of the guidelines.
authors.affiliation: The Guenther Dermatology Research Centre, London, ON, Canada Division of Dermatology, University of Western Ontario, London, ON, Canada dgue@guenthermpc.com.
authors.forename: Lyn C
authors.initials: LC
authors.lastname: Guenther
authors.affiliation: Kirk Barber Research, Calgary, AB, Canada University of Calgary, Calgary, AB, Canada.
authors.forename: Kirk
authors.initials: K
authors.lastname: Barber
authors.affiliation: Searles Dermatology and Aesthetics, Edmonton, AB, Canada.
authors.forename: Gordon E
authors.initials: GE
authors.lastname: Searles
authors.affiliation: Lynderm Research Inc, Markham, ON, Canada University of Toronto, Toronto, ON, Canada.
authors.forename: Charles W
authors.initials: CW
authors.lastname: Lynde
authors.affiliation: SCRIPT, Toronto, ON, Canada.
authors.forename: Peter
authors.initials: P
authors.lastname: Janiszewski
authors.affiliation: SCRIPT, Toronto, ON, Canada.
authors.forename: John
authors.initials: J
authors.lastname: Ashkenas
mesh_terms: D002170:Canada; D002280:Basal Cell Carcinoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D006801:Humans; D055623:Keratosis, Actinic / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*
keywords: actinic keratosis; basal cell carcinoma; photodamage; squamous cell carcinoma