title: Dyspnea on daptomycin: eosinophilic pneumonia.
abstract: We present a case of drug-induced acute eosinophilic pneumonia with characteristic imaging and bronchioloaveolar lavage (BAL) findings. Although not a common diagnosis, it is important to consider in the right clinical scenario, including a patient with presumed pneumonia that does not respond to typical treatment. Diagnosis is confirmed by bronchoscopy with BAL. For drug-induced types, treatment includes removal of the offending agent. Corticosteroids are used if symptoms are severe and can result in rapid clinical improvement.
authors.affiliation: PGY3 Internal Medicine Resident, Alpert Medical School of Brown University, Rhode Island Hospital. Rhode Island Hospital, Department of Internal Medicine.
authors.forename: Ann
authors.initials: A
authors.lastname: Wojtaszczyk
authors.affiliation: Providence VA Medical Center, Division of Pulmonary, Critical Care and Sleep Medicine, Assistant Professor of Medicine, Alpert Medical School of Brown University. Providence, VA Medical Center.
authors.forename: Matthew
authors.initials: M
authors.lastname: Jankowich
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D001999:Bronchoscopy; D017576:Daptomycin / Q000009:adverse effects*; D004417:Dyspnea / Q000209:etiology; D006801:Humans; D008297:Male; D011014:Pneumonia / Q000139:chemically induced* / Q000175:diagnosis* / Q000188:drug therapy; D011657:Pulmonary Eosinophilia / Q000139:chemically induced*; D014057:Tomography, X-Ray Computed
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D017576:Daptomycin
keywords: Daptomycin; adverse drug event; eosinophilic pneumonia