title: Study of the risk factors and complications of diabetes mellitus after live kidney donation.
abstract: OBJECTIVE
  Kidney donors, similar to the general population, are at risk for developing type 2 diabetes mellitus (T2DM). The course of donors who develop T2DM has not been well studied. This work estimates the incidence of diabetes after kidney donation, and some risk factors and complications of diabetes mellitus postdonation.
  
  
  METHODS
  This study examined the records of 2267 donors who donated one of their kidneys between 1976 and 2014 at the Urology and Nephrology Center, Mansoura University, Egypt, and who were regularly followed up at its outpatient clinic. A total of 388 donors were included in the study, and their medical records were revised.
  
  
  RESULTS
  Postdonation weight gain and family history of diabetes mellitus were statistically significant for the development of diabetes mellitus, high or very high albuminuria, and/or decreased creatinine clearance. Metformin and insulin use seemed to significantly reduce the protein excretion and creatinine clearance decline in the studied group.
  
  
  CONCLUSIONS
  There is a significant impact of a family history of diabetes mellitus on the development of high or very high albuminuria and/or decreased creatinine clearance.
authors.affiliation: Department of Dialysis and Transplantation, the Urology and Nephrology Center, Mansoura University, Mansoura, Egypt. Electronic address: mg26984@gmail.com.
authors.forename: Mohammed M
authors.initials: MM
authors.lastname: Abuelmagd
authors.affiliation: Department of Dialysis and Transplantation, the Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
authors.forename: A M
authors.initials: AM
authors.lastname: Nagib
authors.affiliation: Department of Dialysis and Transplantation, the Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Megahed M
authors.initials: MM
authors.lastname: Abuelmagd
authors.affiliation: Department of Dialysis and Transplantation, the Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
authors.forename: A F
authors.initials: AF
authors.lastname: Refaie
authors.affiliation: Department of Dialysis and Transplantation, the Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
authors.forename: Y A
authors.initials: YA
authors.lastname: Elhindi
authors.affiliation: Department of Dialysis and Transplantation, the Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
authors.forename: M F
authors.initials: MF
authors.lastname: Ahmed
authors.affiliation: Department of Dialysis and Transplantation, the Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
authors.forename: M H
authors.initials: MH
authors.lastname: Ali
authors.affiliation: Department of Dialysis and Transplantation, the Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
authors.forename: H M
authors.initials: HM
authors.lastname: Elmaghrabi
authors.affiliation: Department of Dialysis and Transplantation, the Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
authors.forename: M A
authors.initials: MA
authors.lastname: Bakr
mesh_terms: D000328:Adult; D048909:Diabetes Complications / Q000453:epidemiology* / Q000209:etiology; D004534:Egypt / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D055815:Young Adult