title: Homogeneous large-scale crystalline nanoparticle-covered substrate with high SERS performance.
abstract: This article details the surface-enhanced Raman scattering (SERS) performance of plasmonic substrates fabricated by a physical metal evaporation technique that uses no precursor or intermediate coating. We outline a cost-effective nanofabrication protocol that uses common laboratory equipment to produce homogeneously covered crystalline nanoparticle substrates. Our fabrication yields a homogeneous SERS response over the whole surface. The platform is tested with methylene blue diluted at various concentrations to estimate the sensitivity, homogeneity, and reproducibility of the process. The capacity of the substrates is also confirmed with spectroscopic investigations of human microsomal cytochrome b5.
authors.affiliation: Laboratory Interdisciplinaire Carnot de Bourgogne (ICB), UMR CNRS 6303, University of Bourgogne Franche-Comte, Besançon, France.
authors.forename: E N
authors.initials: EN
authors.lastname: Aybeke
authors.forename: Y
authors.initials: Y
authors.lastname: Lacroute
authors.forename: C
authors.initials: C
authors.lastname: Elie-Caille
authors.forename: A
authors.initials: A
authors.lastname: Bouhelier
authors.forename: E
authors.initials: E
authors.lastname: Bourillot
authors.forename: E
authors.initials: E
authors.lastname: Lesniewska
mesh_terms: D015786:Cytochromes b5 / Q000737:chemistry*; D004867:Equipment Design; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000191:economics; D015203:Reproducibility of Results; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013499:Surface Properties; D014961:X-Ray Diffraction / Q000379:methods
chemical_list: D015786:Cytochromes b5