title: [Ischemic resistance of motor axons in children with viral meningitis and Guillain-Barré syndrome].
abstract: The effect of temporal local ischemia at the forearm on ulnar motor nerve conduction velocity in the control (n = 26 children), group of patients with acute period viral meningitis (VM) (n = 16 children), 14 days after the clinical manifestation of VM (n = 11 children) and children with Guillain-Barre syndrome (GBS) in catamnesis (n = 11 children) was evaluated. Less pronounced reactivity of neural conduction on ischemia for 10 minutes (by 50%, p < 0.00001), was seen in children with GBS in catamnesis, comparing to the controls. In the acute period VM also less pronounced reactivity of neural conduction by 29%, than in the controls, was registered. We propose, that ischemic resistance in immune-mediated neuropathy and in the acute period of infection may happen due to cytokine-mediated channelopathy.
authors.forename: A V
authors.initials: AV
authors.lastname: Klimkin
authors.forename: V B
authors.initials: VB
authors.lastname: Voitenkov
authors.forename: N V
authors.initials: NV
authors.lastname: Skripchenko
mesh_terms: D000293:Adolescent; D001369:Axons; D002648:Child; D004576:Electromyography; D005260:Female; D020275:Guillain-Barre Syndrome / Q000503:physiopathology*; D006801:Humans; D007511:Ischemia / Q000503:physiopathology*; D008297:Male; D008587:Meningitis, Viral / Q000503:physiopathology*; D009046:Motor Neurons; D009431:Neural Conduction