title: Facile, Large-Quantity Synthesis of Stable, Tunable-Color Silicon Nanoparticles and Their Application for Long-Term Cellular Imaging.
abstract: We herein introduce a facile, low-cost photochemical method capable of rapid (<40 min) and large-quantity (∼10 g) production of highly fluorescent (quantum yield: 25%) silicon nanoparticles (SiNPs) of tunable optical properties (peak emission wavelength in the range of 470-560 nm) under ambient air conditions, by introducing 1,8-naphthalimide as a reducing agent and surface ligands. The as-prepared SiNPs feature robust storage stability and photostability preserving strong and stable fluorescent during long-term (>3 h) high-power UV irradiation, in contrast to the rapid fluorescence quenching within 2 h of conventional organic dyes and II-VI quantum dots under the same conditions. The as-prepared SiNPs serving as photostable nanoprobes are workable for cellular imaging in long-term manners. Our findings provide a powerful method for mild-condition and low-cost, large-quantity production of highly fluorescent and photostable SiNPs for various promising applications.
authors.affiliation: Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
authors.forename: Yiling
authors.initials: Y
authors.lastname: Zhong
authors.affiliation: Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
authors.forename: Xiaotian
authors.initials: X
authors.lastname: Sun
authors.affiliation: Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
authors.forename: Siyi
authors.initials: S
authors.lastname: Wang
authors.affiliation: Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Peng
authors.affiliation: Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Bao
authors.affiliation: Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Su
authors.affiliation: Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
authors.forename: Youyong
authors.initials: Y
authors.lastname: Li
authors.affiliation: Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
authors.forename: Shuit-Tong
authors.initials: ST
authors.lastname: Lee
authors.affiliation: Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China.
authors.forename: Yao
authors.initials: Y
authors.lastname: He
mesh_terms: D002470:Cell Survival; D003116:Color; D003952:Diagnostic Imaging; D005453:Fluorescence; D006367:HeLa Cells; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D012825:Silicon / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D012825:Silicon
keywords: bioimaging; large-quantity; long-term; photochemical; silicon nanoparticles