title: Deceased-donor Kidney Transplantation: Predictive Factors and Impact on Postoperative Outcome.
abstract: Kidney transplantation (KT) is the treatment of choice in end stage renal disease. Patients proposed for KT have multiple comorbidities, which makes KT a challenge. Our aim was to assess predictive factors for postoperative complications in deceased-donor KT. For data statistical analysis, logistic and linear regressions were used. Between 2012 and 2013, 113 KTs were performed in patients with a mean age 49.9 years. The most prevalent etiology was unknown (32.7%). All patients were in kidney replacement therapy (KRT), for an average of 5.7 years. Most had comorbidities before KT (84.1%), the most frequent hypertension (82.3%). Mean ischemia time (IT) was 1056 minutes. Complications occurred in 93.8% of cases. There were reinterventions in 12.4% of cases, and reinterventions in 13.3%. The time in KRT, IT, and ischemic heart disease had predictive power for the length of hospital stay. Diabetes mellitus before KT and IT were predictors for nephrourologic complications; anemia before KT for hematologic complications; and anemia before KT and time in KRT for cardiovascular complications. The morbidity associated with this disease points to the need to identify and improve the patient-dependent variables influencing its outcome, so as to improve short-term success.
authors.affiliation: Anesthesiology, Intensive Care and Emergency Department, Centro Hospitalar do Porto, Porto, Portugal. Electronic address: mfatimasanto@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: Santos
authors.affiliation: Anesthesiology, Intensive Care and Emergency Department, Centro Hospitalar do Porto, Porto, Portugal.
authors.forename: J
authors.initials: J
authors.lastname: Guimarães
authors.affiliation: Anesthesiology, Intensive Care and Emergency Department, Centro Hospitalar do Porto, Porto, Portugal.
authors.forename: A M
authors.initials: AM
authors.lastname: Araújo
authors.affiliation: Anesthesiology, Intensive Care and Emergency Department, Centro Hospitalar do Porto, Porto, Portugal; Universidade Aberta, Department of Sciences and Technology, Del. Porto, Porto, Portugal.
authors.forename: C S
authors.initials: CS
authors.lastname: Nunes
authors.affiliation: Anesthesiology, Intensive Care and Emergency Department, Centro Hospitalar do Porto, Porto, Portugal.
authors.forename: M
authors.initials: M
authors.lastname: Casal
mesh_terms: D000328:Adult; D002102:Cadaver; D050377:Cold Ischemia / Q000706:statistics & numerical data; D015897:Comorbidity; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery* / Q000628:therapy; D016030:Kidney Transplantation / Q000379:methods*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D006435:Renal Dialysis / Q000706:statistics & numerical data; D012189:Retrospective Studies; D052096:Warm Ischemia / Q000706:statistics & numerical data