title: Review article: The pharmacokinetics and pharmacodynamics of drugs used in inflammatory bowel disease treatment.
abstract: BACKGROUND
  The following review is a compilation of the recent advances and knowledge on the behaviour of the most frequently used compounds to treat inflammatory bowel disease in an organism.
  
  
  RESULTS
  It considers clinical aspects of each entity and the pharmacokinetic/pharmacodynamic relationship supported by the use of plasma monitoring, tissue concentrations, and certain aspects derived from pharmacogenetics.
authors.affiliation: Project Strategy & Science, Grünenthal GmbH, Aachen, Germany.
authors.forename: E G
authors.initials: EG
authors.lastname: Quetglas
authors.forename: A
authors.initials: A
authors.lastname: Armuzzi
authors.forename: S
authors.initials: S
authors.lastname: Wigge
authors.forename: G
authors.initials: G
authors.lastname: Fiorino
authors.forename: L
authors.initials: L
authors.lastname: Barnscheid
authors.forename: M
authors.initials: M
authors.lastname: Froelich
authors.forename: Silvio
authors.initials: S
authors.lastname: Danese
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D003424:Crohn Disease / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D016903:Drug Monitoring; D005765:Gastrointestinal Agents / Q000009:adverse effects / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D006801:Humans; D010597:Pharmacogenetics; D012074:Remission Induction; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D005765:Gastrointestinal Agents