title: Persistent and Recurrent Clostridium difficile Colitis.
abstract: Clostridium difficile infection (CDI) is the most frequent cause of nosocomial diarrhea. It has become a significant dilemma in the treatment of patients, and causes increasing morbidity that, in extreme cases, may result in death. Persistent and recurrent disease hamper attempts at eradication of this infection. Escalating levels of treatment and novel therapeutics are being utilized and developed to treat CDI. Further trials are warranted to definitively determine what protocols can be used to treat persistent and recurrent disease.
authors.affiliation: Section of Colon and Rectal Surgery, MedStar Washington Hospital Center, Washington, District of Columbia.
authors.forename: Shola A
authors.initials: SA
authors.lastname: Cole
authors.affiliation: Interim Chair, Department of Surgery, MedStar Washington Hospital Center; Regional Director, MedStar Colorectal Surgery Program, Washington, District of Columbia.
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Stahl
keywords: BI/NAP1/027; fecal microbiota therapy; recurrent Clostridium difficile