title: Guidelines on gastroesophageal reflux disease.
abstract: Gastroesophageal reflux disease (GERD) is the most common acid-related disorder encountered during clinical practice in Pakistan and is associated with significant impairment of health-related quality of life. A number of guidelines and recommendations for the diagnosis and management of GERD have been published in different countries, but a Pakistani accepted directive by the standards of evidence-based medicine is still lacking. Our aim was to create an understanding of the natural history and presentations of reflux disease; evaluating possible treatment options available for the patients with complex and uncomplicated reflux ailments with the development of current and up to date evidence based endorsement, relevant to the needs of Pakistani health care providers in order to treat oesophageal manifestations of GERD. In order to make such guidelines, a comprehensive literature search was conducted with pertinent evidence reviewed, and quality of relevant data assessed. The resultant conclusions were based on the best available evidence and expert opinion of the authors of technical review panel.
authors.affiliation: Department of Gastroenterology, The Indus Hospital, Karachi.
authors.forename: Saad Khalid
authors.initials: SK
authors.lastname: Niaz
authors.affiliation: Department of Surgery, Dow University of Health Sciences & Civil Hospital Karachi.
authors.forename: Muhammed Saeed
authors.initials: MS
authors.lastname: Quraishy
authors.affiliation: Department of Gastroenterology, The Indus Hospital, Karachi.
authors.forename: Muhammad Ali
authors.initials: MA
authors.lastname: Taj
authors.affiliation: Department of Gastroenterology, Aga Khan University Hospital, Karachi.
authors.forename: Shahab
authors.initials: S
authors.lastname: Abid
authors.affiliation: Department of Medicine, Sheikh Zayyad Hospital, Lahore.
authors.forename: Altaf
authors.initials: A
authors.lastname: Alam
authors.affiliation: Department of Medicine, Fatima Memorial Hospital, Lahore.
authors.forename: Arif Amir
authors.initials: AA
authors.lastname: Nawaz
authors.affiliation: Department of Gastroenterology, Aga Khan University Hospital, Karachi.
authors.forename: Syed Hasnain
authors.initials: SH
authors.lastname: Ali Shah
authors.affiliation: Department of Gastroenterology, PGMI/HMC.
authors.forename: Ijaz Muhammed
authors.initials: IM
authors.lastname: Khan
authors.affiliation: Department of Medicine, Dow University of Health Sciences & Civil Hospital Karachi.
authors.forename: Abdul Rauf
authors.initials: AR
authors.lastname: Memon
authors.affiliation: Department of Medicine, Dow University of Health Sciences & Civil Hospital Karachi.
authors.forename: Bader Fiaz
authors.initials: BF
authors.lastname: Zuberi
authors.affiliation: Department of Medicine, Lahore General Hospital, Lahore.
authors.forename: Ghayasun Nabi
authors.initials: GN
authors.lastname: Tayyab
authors.affiliation: Department of Medicine, Sheikh Zayyad Hospital, Lahore.
authors.forename: Kashif
authors.initials: K
authors.lastname: Malik
authors.affiliation: Department of Medicine, CMH Malir, Karachi.
authors.forename: Shakeel
authors.initials: S
authors.lastname: Mirza
authors.affiliation: Department of Gastroenterologist, Sindh Institute of Urology & Transplantation, Karachi.
authors.forename: Zaigham
authors.initials: Z
authors.lastname: Abbas
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000209:etiology; D000863:Antacids / Q000627:therapeutic use*; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D001466:Barium Sulfate; D001471:Barrett Esophagus / Q000175:diagnosis / Q000209:etiology; D019468:Disease Management; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000209:etiology; D050782:Esophageal pH Monitoring; D004945:Esophagoscopy; D019317:Evidence-Based Medicine; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D010154:Pakistan; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*; D040242:Risk Reduction Behavior
chemical_list: D000863:Antacids; D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors; D001466:Barium Sulfate
keywords: Gastroesophageal reflux disease, Pakistan.