title: Safety and Clinical Outcome of the Delivery of Radiofrequency Nerve Ablation Therapy in a Renal Artery of Unusual Anatomy.
abstract: BACKGROUND
  Catheter-based renal sympathetic denervation is an emerging therapy for resistant hypertension (RHTN) patients, resulting in a significant blood pressure reduction. The presence of accessory renal arteries and anomalous branching patterns are reported in approximately 20-27 % of patients. However, accessory renal arteries, when smaller than 4 mm in diameter, they are out of the inclusion criteria for renal denervation therapy. For this reason patients with evidence of accessory renal arteries have been excluded in previous clinical trials. Recent data suggest that accessory renal arteries may play an important role in non-response therapy when they do not receive renal denervation treatment.
  
  
  METHODS
  In this report, we present the outcome of a patient with resistant hypertension and an anomalous right renal artery, having undergone denervation of both principal and accessory renal arteries. The renal ablation by radiofrequency energy of a distant accessory renal artery resulted in a safe procedure with no clinical complications.
  
  
  CONCLUSIONS
  Consistent with literature the RDN of all, main and accessory renal arteries, was effective in decreasing patient blood pressure while decreasing the need for antihypertensive medication.
authors.affiliation: Hospital Christus Muguerza Alta Especialidad, Monterrey, Nuevo León, Mexico.
authors.forename: Enrique Ponce
authors.initials: EP
authors.lastname: de Leon-Martinez
authors.affiliation: Alizée Pathology, 20 Frederick Rd, Thurmont, MD, 21788, USA.
authors.forename: Javier A
authors.initials: JA
authors.lastname: Garza
authors.affiliation: Hospital Christus Muguerza Alta Especialidad, Monterrey, Nuevo León, Mexico.
authors.forename: Jose R
authors.initials: JR
authors.lastname: Azpiri-Lopez
authors.affiliation: Alizée Pathology, 20 Frederick Rd, Thurmont, MD, 21788, USA.
authors.forename: Krista N
authors.initials: KN
authors.lastname: Dillon
authors.affiliation: Hospital Christus Muguerza, Saltillo, Coahuila, Mexico.
authors.forename: Leonel Olivas
authors.initials: LO
authors.lastname: Salazar
authors.affiliation: Hospital Christus Muguerza, Saltillo, Coahuila, Mexico.
authors.forename: Francisco
authors.initials: F
authors.lastname: Canepa-Campos
authors.affiliation: Alizée Pathology, 20 Frederick Rd, Thurmont, MD, 21788, USA.
authors.forename: Serge D
authors.initials: SD
authors.lastname: Rousselle
authors.affiliation: Alizée Pathology, 20 Frederick Rd, Thurmont, MD, 21788, USA. atellez@alizeepathology.com.
authors.forename: Armando
authors.initials: A
authors.lastname: Tellez
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects; D017115:Catheter Ablation; D004351:Drug Resistance; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D007668:Kidney / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D012077:Renal Artery / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000294:innervation / Q000601:surgery*; D013562:Sympathectomy / Q000379:methods*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents
keywords: Accessory renal arteries; Catheter-based renal denervation; Resistant hypertension