title: Heterochromatin: dark matter or variation on a theme?
abstract: Heterochromatin contributes to the dynamic range of eukaryotic gene expression. In yeast, its ability to suppress transcription is inversely proportional to activator strength. A recent study reveals that Sir silencing proteins enhance the avidity with which nucleosomes assemble, endowing heterochromatin with both repressive and dynamic characteristics.
authors.affiliation: Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA. Electronic address: dgross@lsuhsc.edu.
authors.forename: David S
authors.initials: DS
authors.lastname: Gross
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D006570:Heterochromatin / Q000502:physiology*; D006801:Humans; D038281:Silent Information Regulator Proteins, Saccharomyces cerevisiae / Q000378:metabolism; D015003:Yeasts
chemical_list: D006570:Heterochromatin; D038281:Silent Information Regulator Proteins, Saccharomyces cerevisiae