title: Chronic suppurative otitis media due to nontuberculous mycobacteria: A case of successful treatment with topical boric acid.
abstract: Nontuberculous mycobacteria (NTM) are an increasingly recognized cause of chronic suppurative otitis media in children with tympanostomy tubes. Treatment of this condition is difficult and typically requires a combination of systemic antibiotics and surgical debridement. We present the first case of a 2-year-old male with chronic suppurative otitis media due to NTM who failed systemic antibiotic therapy and was successfully managed with topical boric acid powder. This report highlights the challenges involved in treating this infection, and introduces boric acid as a potentially valuable component of therapy.
authors.affiliation: Infectious Diseases Division, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, 2300 Tupper Street, C-1242, Montreal, Quebec, Canada H3H 1P3. Electronic address: marie-astrid.lefebvre@mail.mcgill.ca.
authors.forename: Marie-Astrid
authors.initials: MA
authors.lastname: Lefebvre
authors.affiliation: Infectious Diseases Division, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, 2300 Tupper Street, C-1242, Montreal, Quebec, Canada H3H 1P3; Department of Medical Microbiology, McGill University Health Centre, 2300 Tupper Street, C-1242, Montreal, Quebec, Canada H3H 1P3; Department of Epidemiology, Biostatistics & Occupational Health, McGill University, Purvis Hall, 1020 Pine Avenue West, Montreal, Quebec, Canada H3A 1A2. Electronic address: caroline.quach@mcgill.ca.
authors.forename: Caroline
authors.initials: C
authors.lastname: Quach
authors.affiliation: Department of Otolaryngology - Head and Neck Surgery, Montreal Children's Hospital, McGill University Health Centre, 2300 Tupper Street, C-1242, Montreal, Quebec, Canada H3H 1P3. Electronic address: sam.daniel@mcgilll.ca.
authors.forename: Sam J
authors.initials: SJ
authors.lastname: Daniel
mesh_terms: D000287:Administration, Topical; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001888:Boric Acids / Q000627:therapeutic use*; D002675:Child, Preschool; D002908:Chronic Disease; D006801:Humans; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000628:therapy*; D009170:Nontuberculous Mycobacteria; D010035:Otitis Media, Suppurative / Q000382:microbiology* / Q000628:therapy*; D011208:Powders
chemical_list: D000891:Anti-Infective Agents, Local; D001888:Boric Acids; D011208:Powders; C032688:boric acid
keywords: Atypical mycobacteria; Boric acid; Chronic otitis media; Chronic suppurative otitis media; Nontuberculous mycobacteria