title: Effect on hemostasis of an absorbable hemostatic gelatin sponge after transrectal prostate needle biopsy.
abstract: OBJECTIVE
  To examine the usefulness of an absorbable hemostatic gelatin sponge for hemostasis after transrectal prostate needle biopsy.
  
  
  METHODS
  The subjects comprised 278 participants who underwent transrectal prostate needle biopsy. They were randomly allocated to the gelatin sponge insertion group (group A: 148 participants) and to the non-insertion group (group B: 130 participants). In group A, the gelatin sponge was inserted into the rectum immediately after biopsy. A biopsy-induced hemorrhage was defined as a case in which a subject complained of bleeding from the rectum, and excretion of blood clots was confirmed. A blood test was performed before and after biopsy, and a questionnaire survey was given after the biopsy.
  
  
  RESULTS
  Significantly fewer participants in group A required hemostasis after biopsy compared to group B (3 (2.0%) vs. 11 (8.5%), P=0.029). The results of the blood tests and the responses from the questionnaire did not differ significantly between the two groups. In multivariate analysis, only "insertion of a gelatin sponge into the rectum" emerged as a significant predictor of hemostasis.
  
  
  CONCLUSIONS
  Insertion of a gelatin sponge into the rectum after transrectal prostate needle biopsy significantly increases hemostasis without increasing patient symptoms, such as pain and a sense of discomfort.
authors.affiliation: Department of Urology, Hiroshima City Asa Hospital, Japan.
authors.forename: Kohei
authors.initials: K
authors.lastname: Kobatake
authors.affiliation: Department of Urology, Hiroshima City Asa Hospital, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Mita
authors.affiliation: Department of Urology, Hiroshima City Asa Hospital, Japan.
authors.forename: Masao
authors.initials: M
authors.lastname: Kato
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D004812:Epidemiologic Methods; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use*; D006487:Hemostasis / Q000502:physiology*; D006489:Hemostatic Techniques / Q000295:instrumentation; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019106:Postoperative Hemorrhage / Q000209:etiology / Q000517:prevention & control; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology; D012007:Rectum / Q000601:surgery; D012016:Reference Values; D015203:Reproducibility of Results; D016896:Treatment Outcome
chemical_list: D006490:Hemostatics