title: The role of perioperative oral nutritional supplementation in elderly patients after hip surgery.
abstract: BACKGROUND
  The effect of perioperative oral nutritional supplementation (ONS) on elderly patients after hip surgery remains controversial. This study intended to ascertain whether perioperative ONS is beneficial for the rehabilitation of elderly patients after hip surgery.
  
  
  METHODS
  We searched databases including PubMed, Embase, and the Cochrane Central Register of Controlled Trials for articles published up to May 2014. Randomized controlled trials of ONS for elderly patients after hip surgery were included.
  
  
  RESULTS
  The combined trials showed that ONS had a positive effect on the serum total protein (P<0.00001) and led to a significantly decreased number of complications (P=0.0005). Furthermore, data from the infection subgroups showed significant decreases in wound infection (P=0.02), respiratory infection (P=0.04), and urinary tract infection (P=0.03). Clinical observation suggests that the intervention may improve the level of serum albumin, although the data did not reach statistical significance (P=0.48). Regarding mortality, there was no significant statistical difference between the intervention group and the control (P=0.93).
  
  
  CONCLUSIONS
  Based on the evidence available, this meta-analysis is consistent with the hypothesis that perioperative ONS can help elderly patients recover after hip surgery and reduce complications.
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
authors.forename: Ming
authors.initials: M
authors.lastname: Liu
authors.affiliation: Department of Pain, Xiamen No 2 Hospital, Xiamen, Fujian Province, People's Republic of China.
authors.forename: Jing
authors.initials: J
authors.lastname: Yang
authors.affiliation: West China School of Medicine, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
authors.forename: Xi
authors.initials: X
authors.lastname: Yu
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Huang
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
authors.forename: Sushan
authors.initials: S
authors.lastname: Vaidya
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
authors.forename: Fuguo
authors.initials: F
authors.lastname: Huang
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan Province, People's Republic of China.
authors.forename: Zhou
authors.initials: Z
authors.lastname: Xiang
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D019587:Dietary Supplements; D006620:Hip Fractures / Q000401:mortality / Q000601:surgery*; D006801:Humans; D019990:Perioperative Care / Q000379:methods*; D011183:Postoperative Complications / Q000453:epidemiology*; D016032:Randomized Controlled Trials as Topic; D012141:Respiratory Tract Infections / Q000453:epidemiology; D012709:Serum Albumin; D013530:Surgical Wound Infection / Q000453:epidemiology; D014552:Urinary Tract Infections / Q000453:epidemiology
chemical_list: D012709:Serum Albumin
keywords: elderly patient; hip surgery; meta-analysis; oral nutrition