title: Characterization, molecular dynamics, and encapsulation ability of β-cyclodextrin polymers crosslinked by polyethylene glycol.
abstract: A series of water-insoluble cyclodextrin polymers (CDP) was prepared by crosslinking β-cyclodextrin (CD) with polyethylene glycol diglycidyl ether (PEGDE). Similarly, a reference CDP was prepared using ethylene glycol diglycidyl ether (EGDE). Increasing the feed ratio of PEGDE to CD in the reaction mixture led to high degrees of crosslinking. Relaxation measurements revealed structural homogeneity among the CDPs, which exhibited mobilities that strongly depended on the chain lengths of the crosslinking agents. In addition, all the CDPs displayed high encapsulation abilities toward bisphenol A (BPA) in aqueous media. In particular, the CDP sample with a low degree of crosslinking by PEGDE showed the highest encapsulation ability toward BPA. In contrast, the CDP crosslinked by EGDE exhibited low encapsulation ability because its highly dense structure, which results from the short chain lengths of the crosslinking agents, hinders the penetration of BPA molecules.
authors.affiliation: Department of Science and Engineering for Materials, Tomakomai National College of Technology, Nishikioka 443, Tomakomai, Hokkaido 059 1275, Japan. Electronic address: kono@sem.tomakomai-ct.ac.jp.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kono
authors.affiliation: Department of Science and Engineering for Materials, Tomakomai National College of Technology, Nishikioka 443, Tomakomai, Hokkaido 059 1275, Japan.
authors.forename: Taichi
authors.initials: T
authors.lastname: Nakamura
authors.affiliation: Department of Science and Engineering for Materials, Tomakomai National College of Technology, Nishikioka 443, Tomakomai, Hokkaido 059 1275, Japan.
authors.forename: Hisaho
authors.initials: H
authors.lastname: Hashimoto
authors.affiliation: Department of Science and Engineering for Materials, Tomakomai National College of Technology, Nishikioka 443, Tomakomai, Hokkaido 059 1275, Japan.
authors.forename: Yuuichi
authors.initials: Y
authors.lastname: Shimizu
mesh_terms: D001559:Benzhydryl Compounds / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry*; D004853:Epoxy Resins / Q000737:chemistry; D056004:Molecular Dynamics Simulation; D010636:Phenols / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D047392:beta-Cyclodextrins / Q000737:chemistry*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D003432:Cross-Linking Reagents; D004853:Epoxy Resins; D010636:Phenols; D011092:Polyethylene Glycols; D047392:beta-Cyclodextrins; C035364:Quetol 651; C031215:betadex; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: Adsorption isotherm; Cyclodextrin polymer; Encapsulation ability; Epoxy-functionalized PEG; Molecular dynamics