title: Factors associated with long-term survival in dogs undergoing liver lobectomy as treatment for liver tumors.
abstract: The objectives of the study were to describe clinicopathologic findings in dogs that underwent surgical treatment of liver tumors and to define outcome-associated variables in this canine population. Medical records of 118 dogs that underwent liver lobectomy were reviewed. Variables were assessed via univariate and multivariate Cox regression analyses. Hazard ratios, median survival times (MSTs), and Kaplan-Meier Survival curves (KMSCs) were created for significant variables. Of the dogs with surgically addressed hepatic tumors, 93% survived to discharge. The MST was not reached. Lethargic dogs had a mortality risk 10.2 times that of non-lethargic dogs. Non-tachypneic dogs had a mortality risk 4.3 times that of tachypneic dogs. Dogs that experienced anesthetic complications had a mortality risk 100 times that of dogs that did not. We conclude that the prognosis associated with liver tumors is good. Lethargy, respiratory rate, and anesthetic complications were associated with outcome.
authors.affiliation: Hope Veterinary Specialists, Malvern, Pennsylvania, USA (Kinsey, Mehler, May); Sonora Veterinary Specialists, Phoenix, Arizona, USA (Gilson); Department of Small Animal Clinical Sciences, Michigan State University, Lansing, Michigan, USA (Hauptman).
authors.forename: Jessica R
authors.initials: JR
authors.lastname: Kinsey
authors.affiliation: Hope Veterinary Specialists, Malvern, Pennsylvania, USA (Kinsey, Mehler, May); Sonora Veterinary Specialists, Phoenix, Arizona, USA (Gilson); Department of Small Animal Clinical Sciences, Michigan State University, Lansing, Michigan, USA (Hauptman).
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Gilson
authors.affiliation: Hope Veterinary Specialists, Malvern, Pennsylvania, USA (Kinsey, Mehler, May); Sonora Veterinary Specialists, Phoenix, Arizona, USA (Gilson); Department of Small Animal Clinical Sciences, Michigan State University, Lansing, Michigan, USA (Hauptman).
authors.forename: Joe
authors.initials: J
authors.lastname: Hauptman
authors.affiliation: Hope Veterinary Specialists, Malvern, Pennsylvania, USA (Kinsey, Mehler, May); Sonora Veterinary Specialists, Phoenix, Arizona, USA (Gilson); Department of Small Animal Clinical Sciences, Michigan State University, Lansing, Michigan, USA (Hauptman).
authors.forename: Steve J
authors.initials: SJ
authors.lastname: Mehler
authors.affiliation: Hope Veterinary Specialists, Malvern, Pennsylvania, USA (Kinsey, Mehler, May); Sonora Veterinary Specialists, Phoenix, Arizona, USA (Gilson); Department of Small Animal Clinical Sciences, Michigan State University, Lansing, Michigan, USA (Hauptman).
authors.forename: Lauren R
authors.initials: LR
authors.lastname: May
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000601:surgery*; D004285:Dogs; D005260:Female; D007431:Intraoperative Complications / Q000662:veterinary*; D008099:Liver / Q000473:pathology / Q000601:surgery; D008113:Liver Neoplasms / Q000601:surgery / Q000662:veterinary*; D008297:Male; D012307:Risk Factors; D016896:Treatment Outcome