title: Reversible thermo-sensitivity induced from varying the hydrogen bonding between the side residues of rationally designed polypeptides.
abstract: Rationally designed polypeptides with similar molecular structures but varying patterns of hydrogen bonding between the side groups have been synthesized and demonstrated to possess distinct solubility and thermal behaviors. Further balancing the ratio of both isopropylamine and ethylenediamine side groups endows the random copolymer with reversible thermo-sensitivity.
authors.affiliation: Key Laboratory of Advanced Polymeric Materials, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China. yxiao@ecust.edu.cn mdlang@ecust.edu.cn.
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
authors.forename: Yan
authors.initials: Y
authors.lastname: Xiao
authors.forename: Heng
authors.initials: H
authors.lastname: Xu
authors.forename: Yebin
authors.initials: Y
authors.lastname: Guan
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Meidong
authors.initials: M
authors.lastname: Lang
mesh_terms: D000595:Amino Acid Sequence; D015195:Drug Design; D006860:Hydrogen Bonding; D008958:Models, Molecular; D010455:Peptides / Q000737:chemistry*; D017433:Protein Structure, Secondary; D012995:Solubility; D013696:Temperature
chemical_list: D010455:Peptides