title: Comparison of markers of ovarian reserve between patients with complete müllerian agenesis and age-matched fertile and infertile controls.
abstract: OBJECTIVE
  To investigate ovarian reserve in complete müllerian agenesis (CMA) patients and to compare the ovarian reserve of CMA patients with that of age-matched fertile and infertile controls.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  University gynecology outpatient clinic.
  
  
  METHODS
  Fifty-eight typical CMA (type A) patients, 8 atypical CMA (type B) patients, 39 fertile patients, and 38 infertile patients were compared for ovarian reserve.
  
  
  METHODS
  Ovarian reserve was evaluated via antimüllerian hormone (AMH) levels and antral follicle counts (AFCs).
  
  
  METHODS
  Investigation of ovarian reserve in CMA patients and a comparison of the ovarian reserve of the CMA patients with that of age-matched fertile and infertile controls.
  
  
  RESULTS
  Fifty-eight type A and eight type B CMA patients and 39 fertile and 38 infertile control patients were assessed for ovarian reserve. The mean (±SD) ages of the type A and type B CMA patients and the fertile and infertile groups were 25.8 ± 5.3, 33.3 ± 5.9, 32.6 ± 4.8, and 33.9 ± 3.3 years, respectively. After age standardization of the groups, AMH levels and AFCs were found to be lower in the atypical CMA group. The differences in AMH levels and AFC were found to be highly significant.
  
  
  CONCLUSIONS
  The present study showed that atypical CMA patients had decreased ovarian reserve compared with age-matched fertile and infertile controls.
authors.affiliation: Department of Obstetrics and Gynecology, Akdeniz University, Antalya, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Ozekinci
authors.affiliation: Department of Obstetrics and Gynecology, Akdeniz University, Antalya, Turkey. Electronic address: ermanmunire@gmail.com.
authors.forename: Munire
authors.initials: M
authors.lastname: Erman Akar
authors.affiliation: Department of Public Health, Akdeniz University, Antalya, Turkey.
authors.forename: Yesim
authors.initials: Y
authors.lastname: Senol
authors.affiliation: Department of Medical Biochemistry, Akdeniz University, Antalya, Turkey.
authors.forename: Sebahat
authors.initials: S
authors.lastname: Ozdem
authors.affiliation: Department of Medical Biochemistry, Akdeniz University, Antalya, Turkey.
authors.forename: Gulbahar
authors.initials: G
authors.lastname: Uzun
authors.affiliation: Department of Medical Microbiology, Akdeniz University, Antalya, Turkey.
authors.forename: Aylin
authors.initials: A
authors.lastname: Daloglu
authors.affiliation: Department of Medical Microbiology, Akdeniz University, Antalya, Turkey.
authors.forename: Gozde
authors.initials: G
authors.lastname: Ongut
mesh_terms: D058489:46, XX Disorders of Sex Development / Q000097:blood* / Q000175:diagnosis*; D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood; D015415:Biomarkers / Q000097:blood; D015331:Cohort Studies; D000013:Congenital Abnormalities / Q000097:blood* / Q000175:diagnosis*; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D007247:Infertility, Female / Q000097:blood* / Q000175:diagnosis*; D009095:Mullerian Ducts / Q000002:abnormalities*; D065851:Ovarian Reserve / Q000502:physiology*; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D015415:Biomarkers; D054304:Anti-Mullerian Hormone
keywords: Complete müllerian agenesis; antimüllerian hormone; antral follicle count; ovarian reserve