title: Metastatic Adenocarcinoma of Prostate in a 28-Year-Old Male: The outcome is poor in young patients?
abstract: Prostate cancer is common in older patients. Rarity in younger population limits the study of natural history and prognosis in this population. Most of the published data has reported poor outcome in younger patients with metastatic prostate cancer. Here, we report a case of prostate cancer in 28-year-old male who presented with bone metastasis. After bilateral inguinal orchidectomy, he was started on anti-androgen therapy and received palliative radiotherapy for bone metastasis. There was only a slight decrease in prostate-specific antigen (PSA) level and pelvic disease post treatment. Subsequently, he was started on opioid analgesics (by World Health Organization, WHO, step ladder) in view of persistent pain. The index case is being presented for its rarity and probable poor outcome in young patients and to stress on the fact that the possibility of primary prostatic adenocarcinoma should be investigated in a male presenting with bone metastasis irrespective of the age.
authors.affiliation: Department of Radiotherapy, All India Institute of Medical Scienses, New Delhi, India.
authors.forename: Renu
authors.initials: R
authors.lastname: Madan
authors.affiliation: Department of Pathology, All India Institute of Medical Scienses, New Delhi, India.
authors.forename: Lavleen
authors.initials: L
authors.lastname: Singh
authors.affiliation: Department of Radiotherapy, All India Institute of Medical Scienses, New Delhi, India.
authors.forename: Kunhi Parambath
authors.initials: KP
authors.lastname: Haresh
authors.affiliation: Department of Radiotherapy, All India Institute of Medical Scienses, New Delhi, India.
authors.forename: Goura Kishore
authors.initials: GK
authors.lastname: Rath
keywords: Biological behavior; Carcinoma prostate; Outcome; Young age