title: Adaptive strategies in the double-extremophilic prokaryotes inhabiting soda lakes.
abstract: Haloalkaliphiles are double extremophilic organisms thriving both at high salinity and alkaline pH. Although numerous haloalkaliphilic representatives have been identified among Archaea and Bacteria over the past 15 years, the adaptations underlying their prosperity at haloalkaline conditions are scarcely known. A multi-level adaptive strategy was proposed to occur in haloalkaliphilic organisms isolated from saline alkaline and soda environments including adjustments in the cell wall structure, plasma membrane lipid composition, membrane transport systems, bioenergetics, and osmoregulation. Isolation of chemolithoautotrophic sulfur-oxidizing γ-Proteobacteria from soda lakes allowed the elucidation of the structural and physiological differences between haloalkaliphilic (prefer NaCl) and natronophilic (prefer NaHCO3/Na2CO3, i.e. soda) microbes.
authors.affiliation: Institute for Interdisciplinary Research in Bio-Nano-Sciences, Molecular Biology Center, Babeş-Bolyai University, 400271 Cluj-Napoca, Romania; Department of Molecular Biology and Biotechnology, Faculty of Biology and Geology, Babeş-Bolyai University, 400006 Cluj-Napoca, Romania. Electronic address: Horia.Banciu@ubbcluj.ro.
authors.forename: Horia Leonard
authors.initials: HL
authors.lastname: Banciu
authors.affiliation: Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical Biology, Moscow 119991, Russia.
authors.forename: Maria S
authors.initials: MS
authors.lastname: Muntyan
mesh_terms: D000222:Adaptation, Physiological; D001105:Archaea / Q000254:growth & development / Q000502:physiology*; D000068536:Bacillota / Q000502:physiology*; D020563:Gammaproteobacteria / Q000254:growth & development / Q000302:isolation & purification / Q000502:physiology*; D060106:Lakes / Q000737:chemistry / Q000382:microbiology*; D010802:Phylogeny; D017693:Sodium Bicarbonate / Q000378:metabolism*; D012965:Sodium Chloride / Q000378:metabolism; D013455:Sulfur / Q000378:metabolism; D014871:Water Microbiology
chemical_list: D012965:Sodium Chloride; D013455:Sulfur; D017693:Sodium Bicarbonate