title: Multidetector computed tomography angiography in clinically suspected hyperacute ischemic stroke in the anterior circulation: an etiological workup in a cohort of Brazilian patients.
abstract: OBJECTIVE
  The potential of computed tomography angiography (CTA) was assessed for early determination of stroke subtypes in a Brazilian cohort of patients with stroke.
  
  
  METHODS
  From July 2011 to July 2013, we selected patients with suspected hyperacute stroke (< 6 hours). Intracranial and cervical arteries were scrutinized on CTA and their imaging features were correlated with concurrent subtype of stroke.
  
  
  RESULTS
  Stroke was documented in 50/106 selected patients (47.2%) based on both clinical grounds and imaging follow-up (stroke group), with statistically significant arterial stenosis and vulnerable plaques on CTA. Intracranial large artery disease was demonstrated in 34% of patients in the stroke group. Partial territorial infarct prevailed (86%) while artery-to-artery embolization was the most common stroke mechanism (52%).
  
  
  CONCLUSIONS
  Multidetector CTA was useful for the etiologic work-up of hyperacute ischemic stroke and facilitated the knowledge about the topographic pattern of brain infarct in accordance with its causative mechanism.
authors.affiliation: Departamento de Neuroradiologia, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brazil.
authors.forename: Felipe Torres
authors.initials: FT
authors.lastname: Pacheco
authors.affiliation: Departamento de Neuroradiologia, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brazil.
authors.forename: Ingrid Aguiar
authors.initials: IA
authors.lastname: Littig
authors.affiliation: Departamento de Neurologia, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brazil.
authors.forename: Rubens Jose
authors.initials: RJ
authors.lastname: Gagliardi
authors.affiliation: Departamento de Neuroradiologia, Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brazil.
authors.forename: Antônio Jose da
authors.initials: AJ
authors.lastname: Rocha
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D020520:Brain Infarction / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000473:pathology; D002545:Brain Ischemia / Q000000981:diagnostic imaging* / Q000209:etiology* / Q000473:pathology; D001938:Brazil; D002533:Cerebral Angiography / Q000379:methods*; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000150:complications / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography / Q000379:methods*; D012189:Retrospective Studies; D013997:Time Factors