title: Toward standardized reporting of drug interactions: the READI checklist for anecdotal reports.
abstract: Anecdotal reports contribute 30% of the literature on adverse drug reactions and interactions. However, the quality of such reports has not been uniformly high. Standardized reporting of clinical studies is of increasing interest, including the CARE guidelines on reporting anecdotal cases in general. Although there are guidelines on evaluating and managing drug-drug interactions, there are none recommending methods for reporting suspected drug interactions. Here, based on published guidelines for reporting suspected adverse drug reactions, I propose a checklist for reporting details of suspected drug interactions, the REporting Anecdotal Drug Interactions (READI) checklist, hoping to stimulate discussion and improve reporting of suspected drug interactions. The checklist includes items relating, among others, to the patient affected, the drugs involved, and the outcome.
authors.affiliation: University of Oxford, Centre for Evidence Based Medicine, Nuffield Department of Primary Care Health Sciences, New Radcliffe House, Radcliffe Observatory Quarter, Woodstock Road, Oxford OX2 6GG, UK.
authors.forename: Jeffrey K
authors.initials: JK
authors.lastname: Aronson
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems / Q000592:standards*; D004347:Drug Interactions; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D009626:Terminology as Topic
keywords: adverse drug reactions; case reports; drug–device interactions; drug–drug interactions; drug–food interactions; drug–herb interactions; reporting guidelines