title: Cerebral relapsing meningioma: a surgical series with lack of reliability of standard parameters establishing prognosis.
abstract: OBJECTIVE
  Meningioma is the most frequent meningeal neoplasm, usually without relapse or metastasis. Patient follow-up is challenging, not standardized and is decided in multidisciplinary case discussion. Our aim was to determine the clinical and histological factors influencing the time to relapse.
  
  
  METHODS
  We conducted a single-Center retrospective study on 38 patients with surgically-excised relapsing meningiomas and collected clinical and pathological data.
  
  
  RESULTS
  Our results show that none of the histological factors included in the WHO classification, nor those not included are related to a shorter time to relapse.
  
  
  CONCLUSIONS
  In our study, none of the histological, immunohistochemical and clinical parameters evaluated seem to be able to predict the time to relapse in meningioma.
authors.affiliation: Department of Pathology, University Hospital of Saint Etienne-North Hospital, Saint Étienne, France fabien.forest@chu-st-etienne.fr.
authors.forename: Fabien
authors.initials: F
authors.lastname: Forest
authors.affiliation: Department of Pathology, University Hospital of Saint Etienne-North Hospital, Saint Étienne, France.
authors.forename: Violaine
authors.initials: V
authors.lastname: Yvorel
authors.affiliation: Department of Neurosurgery, University Hospital of Saint Etienne-North Hospital, Saint Étienne, France.
authors.forename: François
authors.initials: F
authors.lastname: Vassal
authors.affiliation: Department of Medical Informatics, University Hospital of Saint Etienne-North Hospital, Saint Étienne, France.
authors.forename: Béatrice
authors.initials: B
authors.lastname: Trombert
authors.affiliation: Department of Pathology, University Hospital of Saint Etienne-North Hospital, Saint Étienne, France.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Dumollard
authors.affiliation: Department of Neurosurgery, University Hospital of Saint Etienne-North Hospital, Saint Étienne, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Nuti
authors.affiliation: Department of Pathology, University Hospital of Saint Etienne-North Hospital, Saint Étienne, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Péoc'h
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008579:Meningioma / Q000145:classification / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000145:classification / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D015173:Supratentorial Neoplasms / Q000145:classification / Q000473:pathology / Q000601:surgery*
keywords: Meningioma; WHO classification; human; meningeal neoplasm; recurrent brain tumor