title: Controlled proliferation and screening of mammalian cells on a hydrogel-functionalized small molecule microarray.
abstract: A hydrogel-functionalized small molecule microarray has been developed, on which PC-3 cancer cells were selectively grown. Subsequent controlled release of immobilized bioactive compounds enabled cell-based screening to be directly carried out on this platform.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore117543. chmyaosq@nus.edu.sg.
authors.forename: Biwei
authors.initials: B
authors.lastname: Zhu
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
authors.forename: Zhenkun
authors.initials: Z
authors.lastname: Na
authors.forename: Shao Q
authors.initials: SQ
authors.lastname: Yao
mesh_terms: D045744:Cell Line, Tumor; D049109:Cell Proliferation; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry*; D015394:Molecular Structure; D054852:Small Molecule Libraries / Q000138:chemical synthesis / Q000737:chemistry*; D046888:Tissue Array Analysis
chemical_list: D054852:Small Molecule Libraries; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate