title: Clinical Control Study of Endoscopic Full-thickness Resection and Laparoscopic Surgery in the Treatment of Gastric Tumors Arising from the Muscularis Propria.
abstract: BACKGROUND
  Gastric stromal tumors arising from the muscularis propria are located in deeper layers. Endoscopic resection may be contraindicated due to the possibility of perforation. These tumors are therefore usually removed by surgical or laparoscopic procedures. This study evaluated the curative effects, safety and feasibility of endoscopic full-thickness resection (EFR) of gastric stromal tumors originating from the muscularis propria.
  
  
  METHODS
  This study enrolled 92 patients with gastric stromal tumors >2.5 cm originating from the muscularis propria. Fifty patients underwent EFR, and 42 underwent laparoscopic intragastric surgery. Operation time, complete resection rate, length of hospital stay, incidence of complications, and recurrence rates were compared in these two groups.
  
  
  RESULTS
  EFR resulted in complete resection of all 50 gastric stromal tumors, with a mean procedure time of 85 ± 20 min, a mean hospitalization time of 7.0 ± 1.5 days and no complications. Laparoscopic intragastric surgery also resulted in a 100% complete resection rate, with a mean operation time of 88 ± 12 min and a mean hospitalization period of 7.5 ± 1.6 days. The two groups did not differ significantly in operation time, complete resection rates, hospital stay or incidence of complications (P > 0.05). No patient in either group experienced tumor recurrence.
  
  
  CONCLUSIONS
  EFR technique is effective and safe for the resection of gastric stromal tumors arising from the muscularis propria.
authors.forename: Cheng-Rong
authors.initials: CR
authors.lastname: Wu
authors.affiliation: Department of Gastroenterology, Yantai Yuhuangding Hospital Affiliated to Medical College of Qingdao University, Yantai, Shandong 264000, China.
authors.forename: Liu-Ye
authors.initials: LY
authors.lastname: Huang
authors.forename: Juan
authors.initials: J
authors.lastname: Guo
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Cui
authors.forename: Cheng-Ming
authors.initials: CM
authors.lastname: Sun
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Jiang
authors.forename: Zhi-Hua
authors.initials: ZH
authors.lastname: Wang
authors.forename: Ai-Hong
authors.initials: AH
authors.lastname: Ju
mesh_terms: D000328:Adult; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology / Q000601:surgery; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery*; D016896:Treatment Outcome