title: In Vitro Triple Combination of Antifungal Drugs against Clinical Scopulariopsis and Microascus Species.
abstract: Broth microdilution checkerboard techniques based on the methodology of the Clinical and Laboratory Standards Institute (CLSI) were employed to study the triple antifungal combination of caspofungin, posaconazole, and terbinafine against 27 clinical isolates of Scopulariopsis and Microascus species. Synergy was observed for 26 isolates, whereas antagonism was observed for Scopulariopsis candida in this study.
authors.affiliation: Department of Dermatology and Venereology, Peking University First Hospital, Research Center for Medical Mycology, Peking University, Beijing, China Beijing Key Laboratory of Molecular Diagnosis of Dermatoses, Beijing, China.
authors.forename: Limin
authors.initials: L
authors.lastname: Yao
authors.affiliation: Department of Dermatology and Venereology, Peking University First Hospital, Research Center for Medical Mycology, Peking University, Beijing, China Beijing Key Laboratory of Molecular Diagnosis of Dermatoses, Beijing, China.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Wan
authors.affiliation: Department of Dermatology and Venereology, Peking University First Hospital, Research Center for Medical Mycology, Peking University, Beijing, China Beijing Key Laboratory of Molecular Diagnosis of Dermatoses, Beijing, China.
authors.forename: Ruoyu
authors.initials: R
authors.lastname: Li
authors.affiliation: Department of Dermatology and Venereology, Peking University First Hospital, Research Center for Medical Mycology, Peking University, Beijing, China Beijing Key Laboratory of Molecular Diagnosis of Dermatoses, Beijing, China jinyu@medmail.com.cn.
authors.forename: Jin
authors.initials: J
authors.lastname: Yu
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology; D001203:Ascomycota / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D000077336:Caspofungin; D026141:Drug Resistance, Multiple, Fungal; D004359:Drug Therapy, Combination; D054714:Echinocandins / Q000494:pharmacology*; D006801:Humans; D055666:Lipopeptides; D008826:Microbial Sensitivity Tests; D009181:Mycoses / Q000188:drug therapy; D009281:Naphthalenes / Q000494:pharmacology*; D060645:Scopulariopsis / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D000077291:Terbinafine; D014230:Triazoles / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D009281:Naphthalenes; D014230:Triazoles; C101425:posaconazole; D000077336:Caspofungin; D000077291:Terbinafine