title: [Indicators of the human immunodeficiency virus drug resistance to antiretroviral drugs in HIV-infected individuals in the Siberian Federal District in 2010-2012].
abstract: The prevalence of the mutations of resistance to the main three classes of antiretroviral agents in patients receiving antiretroviral therapy was tested. Among the main drug resistance mutations for the entire period of observation was a high frequency of the occurrence M184V mutation, K101E, K103N, Y181C, and G190S influencing the development of the HIV resistance to nucleoside and non-nucleoside reverse transcriptase inhibitors. The problems of the practical application of the study of HIV drug resistance in the regions of the Siberian Federal District were emphasized.
authors.forename: A N
authors.initials: AN
authors.lastname: Kolomeets
authors.forename: E S
authors.initials: ES
authors.lastname: Dovgopolyuk
authors.forename: I V
authors.initials: IV
authors.lastname: Sergeeva
authors.forename: V K
authors.initials: VK
authors.lastname: Yastrebov
authors.forename: A T
authors.initials: AT
authors.lastname: Tyumentsev
mesh_terms: D024882:Drug Resistance, Viral / Q000235:genetics*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000235:genetics*; D015497:HIV-1 / Q000235:genetics*; D006801:Humans; D008297:Male; D017354:Point Mutation; D018894:Reverse Transcriptase Inhibitors; D012800:Siberia
chemical_list: D018894:Reverse Transcriptase Inhibitors