title: Cardioprotective potential of Irish macroalgae: generation of glycine betaine and dimethylsulfoniopropionate containing extracts by accelerated solvent extraction.
abstract: Accelerated solvent extraction (ASE®) was used to generate 18 macroalgal extracts from Irish seaweeds. The glycine betaine and dimethylsulfoniopriopionate content of the generated ASE® extracts were estimated using (1)H-NMR and confirmed for selected extracts using ultra performance liquid chromatography and mass spectrometry. Dimethylsulfoniopriopionate was only identified in the ASE® extract generated from Codium fragile ISCG0029. Glycine betaine was identified in the ASE® extract generated from Ulva intestinalis ISCG0356 using (1)H-NMR. Mass spectrometry analysis found that the seaweed species Cytoseira nodicaulis ISCG0070, Cytoseira tamariscofolia ISCG0283, and Polysiphonia lanosa ISCG0462 also had a glycine betaine content that ranged from 1.39 ng/ml to 105.11 ng/ml. Generated ASE® macroalgal extracts have potential for use as functional food ingredients in food products.
authors.affiliation: Food Biosciences Department, Teagasc Food Research Centre, Ashtown, D15, Dublin, Ireland.
authors.forename: Juan
authors.initials: J
authors.lastname: Valverde
authors.affiliation: Food Biosciences Department, Teagasc Food Research Centre, Ashtown, D15, Dublin, Ireland.
authors.forename: Maria
authors.initials: M
authors.lastname: Hayes
authors.affiliation: Food Biosciences Department, Teagasc Food Research Centre, Ashtown, D15, Dublin, Ireland.
authors.forename: Pádraig
authors.initials: P
authors.lastname: McLoughlin
authors.affiliation: Food Biosciences Department, Teagasc Food Research Centre, Ashtown, D15, Dublin, Ireland.
authors.forename: Dilip K
authors.initials: DK
authors.lastname: Rai
authors.affiliation: Irish Seaweed Research Group, Ryan Institute, Environmental, Marine and Energy Research, National University of Ireland, Galway, Ireland.
authors.forename: Anna
authors.initials: A
authors.lastname: Soler-Vila
mesh_terms: D001622:Betaine / Q000737:chemistry / Q000302:isolation & purification*; D002316:Cardiotonic Agents / Q000737:chemistry / Q000302:isolation & purification*; D002853:Chromatography, Liquid; D055951:Functional Food; D013058:Mass Spectrometry; D012624:Seaweed / Q000737:chemistry*; D012997:Solvents; D013452:Sulfonium Compounds / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D002316:Cardiotonic Agents; D012997:Solvents; D013452:Sulfonium Compounds; D001622:Betaine; C068078:dimethylpropiothetin