title: [Effect of inert gas xenon on the functional state of nucleated cells of peripheral blood during freezing].
abstract: A new method of preservation of nucleated cells in the electric refrigerator with xenon. After slow freezing and storage is even one day at -80 °C persists for more than 60% leukocytes. Cell membranes are resistant to the vital dye. In 85% of granulocytes stored baseline lysosomal-cationic protein, reduced lipid peroxidation and antioxidant activity. Cryopreservation of biological objects in inert gases is a promising direction in the practice of medicine and can be an alternative to the traditional method using liquid nitrogen.
authors.forename: D S
authors.initials: DS
authors.lastname: Laptev
authors.forename: T V
authors.initials: TV
authors.lastname: Polezhaeva
authors.forename: O O
authors.initials: OO
authors.lastname: Zaitseva
authors.forename: A N
authors.initials: AN
authors.lastname: Khudyakov
authors.forename: S V
authors.initials: SV
authors.lastname: Utemov
authors.forename: M G
authors.initials: MG
authors.lastname: Knyazev
authors.forename: A A
authors.initials: AA
authors.lastname: Kostyaev
mesh_terms: D000975:Antioxidants / Q000378:metabolism; D001793:Blood Preservation / Q000379:methods*; D015925:Cryopreservation / Q000379:methods*; D006098:Granulocytes / Q000166:cytology* / Q000378:metabolism*; D006801:Humans; D015227:Lipid Peroxidation; D008247:Lysosomes / Q000378:metabolism; D014978:Xenon / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D014978:Xenon