title: Preoperative Glucagon-like peptide-1 receptor imaging reduces surgical trauma and pancreatic tissue loss in insulinoma patients: a report of three cases.
abstract: BACKGROUND
  Insulinomas are rare tumors, in the majority of cases best treated by surgical resection. Preoperative localization of insulinoma is challenging. The more precise the preoperative localization the less invasive and safer is the resection. The purpose of the study is to check the impact of a new technique to localize insulinoma on the surgical strategy.
  
  
  RESULTS
  We present exact preoperative localization with Glucagon-like peptide-1 receptor (GLP-1R) imaging. This allows a more precise resection thereby reducing surgical access trauma, loss of healthy pancreatic tissue and increasing safety and quality of the surgical intervention.
  
  
  CONCLUSIONS
  With the help of precise preoperative localization of insulinoma with GLP-1R imaging the surgeon is able to minimize the amount of resected healthy pancreatic tissue. We hypothesize that GLP-1R imaging will become a preoperative diagnostic tool to be used for many patients scheduled for open or laparoscopic insulinoma resection.
authors.affiliation: Department of Visceral Surgery and Medicine, Inselspital, University Hospital, CH-3010 Berne, Switzerland.
authors.forename: Anna Silvia
authors.initials: AS
authors.lastname: Wenning
authors.affiliation: Division of Endocrinology, Diabetology and Clinical Nutrition, Inselspital, University Hospital, Berne, Switzerland.
authors.forename: Paul
authors.initials: P
authors.lastname: Kirchner
authors.affiliation: Department of Radiology, Division of Nuclear Medicine, University Hospital, Basel, Switzerland.
authors.forename: Kwadwo
authors.initials: K
authors.lastname: Antwi
authors.affiliation: Department of Radiology, Division of Nuclear Medicine, University Hospital, Basel, Switzerland.
authors.forename: Melpomeni
authors.initials: M
authors.lastname: Fani
authors.affiliation: Department of Radiology, Division of Nuclear Medicine, University Hospital, Basel, Switzerland.
authors.forename: Damian
authors.initials: D
authors.lastname: Wild
authors.affiliation: Division of Endocrinology, Diabetology and Clinical Nutrition, Inselspital, University Hospital, Berne, Switzerland.
authors.forename: Emanuel
authors.initials: E
authors.lastname: Christ
authors.affiliation: Department of Visceral Surgery and Medicine, Inselspital, University Hospital, CH-3010 Berne, Switzerland.
authors.forename: Beat
authors.initials: B
authors.lastname: Gloor