title: Interdisciplinary orthodontic treatment for a patient with generalized aggressive periodontitis: Assessment of IgG antibodies to identify type of periodontitis and correct timing of treatment.
abstract: Aggressive periodontitis is a great challenge to clinicians when providing orthodontic treatment because of the potential for progression of periodontal disease. In this article, we report the successful comprehensive orthodontic treatment of bimaxillary protrusion and severe crowding in an adult with generalized aggressive periodontitis. A woman, aged 22 years 7 months, with a chief complaint of incisal crowding was diagnosed with a skeletal Class I malocclusion associated with severe anterior crowding, possibly worsened by generalized aggressive periodontitis. In addition to a periodontal examination, a blood IgG antibody titer analysis and microbiologic examination for periodontal pathogens were used to diagnose the type of periodontal disease and determine the proper timing to initiate orthodontic treatment. The total active treatment period was 28 months, followed by periodontal prostheses and regeneration therapy. Consequently, satisfactory facial profile, occlusion, and periodontal health were maintained for at least 36 months. These results indicate that efficient screening is important for providing successful orthodontic treatment in patients with advanced periodontal disease. This report also demonstrates the diagnostic importance of blood IgG antibody titer assays and microbiologic examinations to detect periodontal pathogens.
authors.affiliation: Assistant professor, Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan. Electronic address: ishihara@md.okayama-u.ac.jp.
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Ishihara
authors.affiliation: Assistant professor, Division of General Dentistry, Kyushu University Hospital, Fukuoka, Japan.
authors.forename: Kazuya
authors.initials: K
authors.lastname: Tomikawa
authors.affiliation: Associate professor, Division of Orthodontics, College of Dentistry, Ohio State University, Columbus, Ohio.
authors.forename: Toru
authors.initials: T
authors.lastname: Deguchi
authors.affiliation: Assistant professor, Division of Oral and Maxillofacial Biopathological Surgery, Faculty of Medicine, Tottori University, Yonago, Japan.
authors.forename: Tadashi
authors.initials: T
authors.lastname: Honjo
authors.affiliation: Assistant professor, Department of Comprehensive Dentistry, Okayama University Hospital, Okayama, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Suzuki
authors.affiliation: Assistant professor, Department of Comprehensive Dentistry, Okayama University Hospital, Okayama, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kono
authors.affiliation: Professor and chair, Department of Oral Rehabilitation and Regenerative Medicine, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
authors.forename: Takuo
authors.initials: T
authors.lastname: Kuboki
authors.affiliation: Professor and chair, Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kamioka
authors.affiliation: Professor and chair, Department of Pathophysiology-Periodontal Science, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
authors.forename: Shogo
authors.initials: S
authors.lastname: Takashiba
authors.affiliation: Professor and chair, Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Osaka University, Suita, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamashiro
mesh_terms: D016976:Aggregatibacter actinomycetemcomitans / Q000276:immunology; D010520:Aggressive Periodontitis / Q000382:microbiology / Q000628:therapy*; D016301:Alveolar Bone Loss / Q000628:therapy; D000907:Antibodies, Bacterial / Q000097:blood; D002508:Cephalometry / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008311:Malocclusion, Angle Class I / Q000097:blood / Q000628:therapy*; D009910:Oral Hygiene; D010347:Patient Care Planning; D010348:Patient Care Team; D010515:Periodontal Prosthesis; D016966:Porphyromonas gingivalis / Q000276:immunology; D018713:Prevotella intermedia / Q000276:immunology; D013997:Time Factors; D014087:Tooth Movement Techniques / Q000379:methods; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G