title: Pulse transit time differential measurement by fiber Bragg grating pulse recorder.
abstract: The present study reports a noninvasive technique for the measurement of the pulse transit time differential (PTTD) from the pulse pressure waveforms obtained at the carotid artery and radial artery using fiber Bragg grating pulse recorders (FBGPR). PTTD is defined as the time difference between the arrivals of a pulse pressure waveform at the carotid and radial arterial sites. The PTTD is investigated as an indicator of variation in the systolic blood pressure. The results are validated against blood pressure variation obtained from a Mindray Patient Monitor. Furthermore, the pulse wave velocity computed from the obtained PTTD is compared with the pulse wave velocity obtained from the color Doppler ultrasound system and is found to be in good agreement. The major advantage of the PTTD measurement via FBGPRs is that the data acquisition system employed can simultaneously acquire pulse pressure waveforms from both FBGPRs placed at carotid and radial arterial sites with a single time scale, which eliminates time synchronization complexity.
authors.affiliation: Indian Institute of Science, Department of Instrumentation and Applied Physics, Bangalore, India.
authors.forename: Sharath
authors.initials: S
authors.lastname: Umesh
authors.affiliation: Indian Institute of Science, Department of Instrumentation and Applied Physics, Bangalore, IndiabIndian Institute of Science, Department of Electrical Communication Engineering, Bangalore, India.
authors.forename: Srivani
authors.initials: S
authors.lastname: Padma
authors.affiliation: Indian Institute of Science, Department of Instrumentation and Applied Physics, Bangalore, India.
authors.forename: Shikha
authors.initials: S
authors.lastname: Ambastha
authors.affiliation: M.S. Ramaiah Medical College, Department of Radio Diagnosis, Bangalore, India.
authors.forename: Anand
authors.initials: A
authors.lastname: Kalegowda
authors.affiliation: Indian Institute of Science, Department of Instrumentation and Applied Physics, Bangalore, IndiadIndian Institute of Science, Robert Bosch Center for Cyber Physical Systems and Applied Photonics Initiative, Bangalore, India.
authors.forename: Sundarrajan
authors.initials: S
authors.lastname: Asokan
mesh_terms: D000328:Adult; D062186:Arterial Pressure / Q000502:physiology*; D001795:Blood Pressure Determination / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005260:Female; D005336:Fiber Optic Technology / Q000295:instrumentation*; D006801:Humans; D008297:Male; D063177:Pulse Wave Analysis / Q000295:instrumentation*; D012031:Refractometry / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity