title: [Adjuvants in modern anesthesia - lidocaine].
abstract: Local anesthetics (LA) are well known for their antinociceptive and antiarrhythmic properties, but exert alternative effects, i.e. anti-inflammatory activity, as well. These immunomodulatory properties might contribute to the beneficial effects observed in the clinical setting, when intravenous lidocaine is given perioperatively. Systemic LA were shown to attenuate postoperative pain, accelerate the return of bowel function and shorten length of hospital stay in patients undergoing abdominal surgery.
authors.forename: Susanne
authors.initials: S
authors.lastname: Picardi
authors.forename: Philipp
authors.initials: P
authors.lastname: Lirk
authors.forename: Romy
authors.initials: R
authors.lastname: Boeckh
authors.forename: Markus W
authors.initials: MW
authors.lastname: Hollmann
mesh_terms: D000005:Abdomen / Q000601:surgery*; D000758:Anesthesia / Q000639:trends; D000779:Anesthetics, Local / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant / Q000379:methods; D006801:Humans; D007249:Inflammation / Q000517:prevention & control*; D007262:Infusions, Intravenous; D008012:Lidocaine / Q000008:administration & dosage*; D010149:Postoperative Pain / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine