title: Malignant causes of fever of unknown origin.
abstract: The presence of fever in malignancy usually indicates infection, though transfusion, thrombosis and drugs are also culprits. However, particularly in some tumour types, fever can also be a paraneoplastic syndrome, caused by the malignancy itself. This can be a difficult diagnosis to establish and presents a therapeutic challenge to the physician when the underlying malignancy is not easily treated.
authors.affiliation: SpR haematology, Royal London Hospital, London, UK vanessa.foggo@bartshealth.nhs.uk.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Foggo
authors.affiliation: professor of haematology, St Bartholomew's Hospital, London, UK.
authors.forename: Jamie
authors.initials: J
authors.lastname: Cavenagh
mesh_terms: D005871:Castleman Disease / Q000150:complications*; D005335:Fever of Unknown Origin / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications*; D009288:Naproxen; D009369:Neoplasms / Q000150:complications*
chemical_list: D009288:Naproxen
keywords: FUO; Neoplastic fever; fever; malignancy