title: Real-time investigation of cytochrome c release profiles in living neuronal cells undergoing amyloid beta oligomer-induced apoptosis.
abstract: Intracellular Cyt c release profiles in living human neuroblastoma undergoing amyloid β oligomer (AβO)-induced apoptosis, as a model Alzheimer's disease-associated pathogenic molecule, were analysed in a real-time manner using plasmon resonance energy transfer (PRET)-based spectroscopy.
authors.affiliation: School of Materials Science and Engineering, Gwangju Institute of Science and Technology, Gwangju 500-715, Republic of Korea.
authors.forename: Jae Young
authors.initials: JY
authors.lastname: Lee
authors.forename: Younggeun
authors.initials: Y
authors.lastname: Park
authors.forename: San
authors.initials: S
authors.lastname: Pun
authors.forename: Sung Sik
authors.initials: SS
authors.lastname: Lee
authors.forename: Joe F
authors.initials: JF
authors.lastname: Lo
authors.forename: Luke P
authors.initials: LP
authors.lastname: Lee
mesh_terms: D016229:Amyloid beta-Peptides / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology*; D002460:Cell Line; D003199:Computer Systems; D045304:Cytochromes c / Q000378:metabolism*; D031541:Fluorescence Resonance Energy Transfer / Q000379:methods*; D006801:Humans; D057054:Molecular Imaging / Q000379:methods; D009474:Neurons / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D020349:Surface Plasmon Resonance / Q000379:methods*
chemical_list: D016229:Amyloid beta-Peptides; D045304:Cytochromes c