title: A party of three: iNKT cells in GVHD prevention.
abstract: In this issue of Blood, Schneidawind et al demonstrate that the adoptive transfer of CD4+ invariant natural killer T (iNKT) cells from third-party mice protects from lethal graft-versus-host disease (GVHD) through expansion of donor regulatory T cells (Tregs) in a murine model of allogeneic hematopoietic cell transplantation (HCT).
authors.affiliation: UNIVERSITY HOSPITAL BONN.
authors.forename: Annkristin
authors.initials: A
authors.lastname: Heine
authors.affiliation: UNIVERSITY HOSPITAL BONN.
authors.forename: Peter
authors.initials: P
authors.lastname: Brossart
mesh_terms: D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000502:physiology* / Q000637:transplantation*; D005260:Female; D006086:Graft vs Host Disease / Q000401:mortality* / Q000517:prevention & control*; D016219:Immunotherapy, Adoptive / Q000379:methods*; D007694:Killer Cells, Natural / Q000502:physiology* / Q000637:transplantation*; D008297:Male