title: Regulation of orexigenic AgRP neurons: A third way?
abstract: Arcuate AgRP neurons are critical for food intake. Two pathways leading to AgRP neuron activation and food intake include regulation by peripheral hormones leptin and ghrelin, and neuronal regulation via glutamatergic inputs. In a recent article in Cell Reports, Yang et al. demonstrate 'a third way,' regulation by resident astrocytes.
authors.affiliation: Division of Pediatric Endocrinology, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA. Electronic address: nathan.bingham@vanderbilt.edu.
authors.forename: Nathan C
authors.initials: NC
authors.lastname: Bingham
authors.affiliation: Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, USA.
authors.forename: Roger D
authors.initials: RD
authors.lastname: Cone
mesh_terms: D054369:Agouti-Related Protein / Q000378:metabolism*; D000818:Animals; D001253:Astrocytes / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D043682:Receptor, Adenosine A1 / Q000378:metabolism*
chemical_list: D054369:Agouti-Related Protein; D043682:Receptor, Adenosine A1
keywords: AgRP neurons; adenosine; astrocytes; food intake; glia