title: Relation between uric acid and metabolic syndrome in subjects with cardiometabolic risk.
abstract: Objective To identify possible relations between serum uric acid levels and metabolic syndrome and its components in a population with cardiometabolic risk. Methods This cross-sectional study included 80 subjects (46 women), with mean age of 48±16 years, seen at the Cardiovascular Health Program. Results The prevalence of hyperuricemia and metabolic syndrome was 6.3% and 47.1%, respectively. Uric acid level was significantly higher in individuals with metabolic syndrome (5.1±1.6mg/dL), as compared to those with no syndrome or with pre-syndrome (3.9±1.2 and 4.1±1.3mg/dL, respectively; p<0.05). The uric acid levels were significantly higher in men presenting abdominal obesity, and among women with abdominal obesity, lower HDL-c levels and higher blood pressure (p<0.05). Conclusion Uric acid concentrations were positively related to the occurrence of metabolic syndrome and its components, and there were differences between genders. Our results indicate serum uric acid as a potential biomarker for patients with cardiometabolic risk.
authors.affiliation: Universidade Federal de Viçosa, Viçosa, MG, Brazil.
authors.forename: Hellen Abreu da
authors.initials: HA
authors.lastname: Silva
authors.affiliation: Universidade Federal de Viçosa, Viçosa, MG, Brazil.
authors.forename: Júlia Cristina Cardoso
authors.initials: JC
authors.lastname: Carraro
authors.affiliation: Universidade Federal de Viçosa, Viçosa, MG, Brazil.
authors.forename: Josefina
authors.initials: J
authors.lastname: Bressan
authors.affiliation: Universidade Federal de Viçosa, Viçosa, MG, Brazil.
authors.forename: Helen Hermana Miranda
authors.initials: HH
authors.lastname: Hermsdorff
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D001938:Brazil / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000097:blood* / Q000150:complications / Q000453:epidemiology; D008076:Cholesterol, HDL / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood; D033461:Hyperuricemia / Q000097:blood* / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood* / Q000453:epidemiology; D008875:Middle Aged; D056128:Obesity, Abdominal; D015995:Prevalence; D018570:Risk Assessment; D012737:Sex Factors; D011795:Surveys and Questionnaires; D014527:Uric Acid / Q000097:blood*
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D008076:Cholesterol, HDL; D014527:Uric Acid