title: Porcine Model to Evaluate Real-Time Intraocular Pressure During Femtosecond Laser Cataract Surgery.
abstract: To investigate the changes in intraocular pressure (IOP) in porcine eyes during femtosecond laser-assisted cataract surgery using a liquid-optic interface system.
  
  
  
  Femtosecond laser cataract surgery with the Catalys™ was performed on freshly enucleated porcine eyes in Oftalvist Moncloa, Madrid, Spain. Capsulorhexis and lens fragmentation were completed in all the eyes without complications. IOP was measured with a reusable blood pressure transducer connected by direct cannulation to the anterior chamber, recording data before suction (basal), at the beginning of the suction phase, every five seconds during femtosecond procedure and after the removal of the suction ring from the eye.
  
  
  
  Nine porcine eyes were used in this study. Basal IOP before suction was 5.67 ± 2.39 mmHg, rising to 20.33 ± 4.18 mmHg at the beginning of the suction phase (p < 0.001). During femtosecond procedure, pressure reached a value of 19.74 ± 4.31 mmHg, remaining stable during the entire process. The IOP recorded prior to removal of the suction ring was 21.00 ± 6.93 mmHg, returning to basal values in all the eyes after the suction ring was removed, with no statistical differences between basal and post-suction IOPs. Total femtosecond procedure time was 125.9 ±  15.9 s.
  
  
  
  Real-time IOP can be measured during surgery using a transducer connected to the anterior chamber. The results showed a significant increase in IOP during the procedure due to the pressure exerted by the suction ring but not by the effect of the femtosecond laser.
authors.affiliation: a Hospital Moncloa, Oftalvist Madrid , Madrid , Spain .
authors.forename: Marta
authors.initials: M
authors.lastname: Ibarz
authors.affiliation: b VISSUM Madrid , Madrid , Spain .
authors.forename: José Luis
authors.initials: JL
authors.lastname: Hernández-Verdejo
authors.affiliation: c Hospital Príncipe de Asturias , Alcalá de Henares, Madrid , Spain .
authors.forename: Gema
authors.initials: G
authors.lastname: Bolívar
authors.affiliation: d Clínica Vistahermosa, Oftalvist Alicante , Alicante , Spain , and.
authors.forename: Pedro
authors.initials: P
authors.lastname: Tañá
authors.affiliation: d Clínica Vistahermosa, Oftalvist Alicante , Alicante , Spain , and.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Rodríguez-Prats
authors.affiliation: e Hospital Príncipe de Asturias, Universidad de Alcalá de Henares , Madrid , Spain.
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Teus
mesh_terms: D000818:Animals; D002387:Cataract Extraction / Q000379:methods*; D004195:Disease Models, Animal; D004867:Equipment Design; D005500:Follow-Up Studies; D007429:Intraocular Pressure / Q000502:physiology*; D053685:Laser Therapy / Q000379:methods*; D016343:Monitoring, Intraoperative / Q000379:methods*; D013552:Swine; D013997:Time Factors; D014065:Tonometry, Ocular / Q000295:instrumentation*
keywords: Cataract; femtosecond laser; intraocular pressure; porcine model