title: Metal-Free Iodine-Catalyzed Direct Arylthiation of Substituted Anilines with Thiols.
abstract: Iodine-catalyzed direct arylthiation of substituted anilines for the synthesis of various diaryl sulfides has been developed under metal- and solvent-free conditions. The present method uses readily available thiols as the arylthiation reagents, and environmentally friendly and inexpensive I2 as the catalyst. Importantly, no base or ligand was necessary. Such a simple, efficient, and economical transformation provides an attractive approach to various diaryl sulfides in good to excellent yields.
authors.affiliation: The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, P. R. China.
authors.forename: Daoshan
authors.initials: D
authors.lastname: Yang
authors.affiliation: The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, P. R. China.
authors.forename: Kelu
authors.initials: K
authors.lastname: Yan
authors.affiliation: The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, P. R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.affiliation: The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, P. R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
authors.affiliation: The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, P. R. China.
authors.forename: Mengqi
authors.initials: M
authors.lastname: Zhang
authors.affiliation: The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, P. R. China.
authors.forename: Xuguang
authors.initials: X
authors.lastname: Sheng
authors.affiliation: The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, P. R. China.
authors.forename: Guoqing
authors.initials: G
authors.lastname: Li
authors.affiliation: The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, P. R. China.
authors.forename: Shenglei
authors.initials: S
authors.lastname: Lu
authors.affiliation: The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, Shandong, P. R. China.
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D007455:Iodine / Q000737:chemistry*; D008024:Ligands; D008670:Metals / Q000737:chemistry*; D015394:Molecular Structure; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D013440:Sulfides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000814:Aniline Compounds; D008024:Ligands; D008670:Metals; D013438:Sulfhydryl Compounds; D013440:Sulfides; D007455:Iodine; C023650:aniline