title: Measuring psoriatic disease in clinical practice. An expert opinion position paper.
abstract: Psoriasis is a common, immune-mediated chronic inflammatory disease with a primary involvement of skin and joints, affecting approximately 2% of the population worldwide. Up to one third of patients with psoriasis are diagnosed with psoriatic arthritis (PsA). Psoriasis and PsA are heterogeneous diseases whose severity depends on a number of clinical factors, such as areas affected and pattern of involvement, and are associated with a range of comorbid diseases and risk factors, including obesity, metabolic syndrome, cardiovascular disease and liver disease. Thus measuring the severity of psoriatic disease needs to take into account the multidimensional aspects of the disease. Subjective measures including the impairment in quality of life or in daily living activities as well as the presence of cardio-metabolic comorbidities, are important for the outcome and add further levels of complexity that, to a certain extent, need to be assessed. Because of the wide range of comorbid conditions associated with psoriasis, comprehensive screening and treatment must be implemented for a most effective managing of psoriasis patients. A joint dermatologist-rheumatologist roundtable discussion was convened to share evidence on the real-life use of methods for measuring psoriasis severity comprehensively. Our objective was to provide an expert position on which clinical variables are to be taken into account when considering patients affected by psoriasis and/or PsA globally and on the assessment tools more suitable for measuring disease activity and/or severity in clinical practice.
authors.affiliation: Academic Rheumatology Unit, Department of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Campobasso, Italy. Electronic address: enniolubrano@hotmail.com.
authors.forename: Ennio
authors.initials: E
authors.lastname: Lubrano
authors.affiliation: Unit of Rheumatology, AUSL 4, Prato, Italy. Electronic address: fbrzcantini@gmail.com.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Cantini
authors.affiliation: Unit of Dermatology, NESMOS Department, "Sapienza" University of Rome, Italy. Electronic address: acostanzo2000@gmail.com.
authors.forename: Antonio
authors.initials: A
authors.lastname: Costanzo
authors.affiliation: Department of Medicine, Section of Dermatology, University of Verona, Italy. Electronic address: giampiero.girolomoni@univr.it.
authors.forename: Giampiero
authors.initials: G
authors.lastname: Girolomoni
authors.affiliation: Department of Medical-Surgical Critical Area, Section of Clinical, Preventive and Oncological Dermatology, University of Florence, Italy. Electronic address: francesca.prignano@unifi.it.
authors.forename: Francesca
authors.initials: F
authors.lastname: Prignano
authors.affiliation: Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, Italy. Electronic address: ignazioolivieri@tiscali.it.
authors.forename: Ignazio
authors.initials: I
authors.lastname: Olivieri
authors.affiliation: Rheumatology Unit, Department of Clinical Medicine and Surgery, University of Naples "FEDERICO II", Italy. Electronic address: rscarpa@unina.it.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Scarpa
authors.affiliation: Rheumatology Unit, Department of Internal Medicine and Medical Specialties, University "Sapienza" of Rome, Umberto I Polyclinic, Rome, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Spadaro
authors.affiliation: Rheumatology Unit, L. Sacco University Hospital, Milan, Italy. Electronic address: atzenifabiola@hotmail.com.
authors.forename: Fabiola
authors.initials: F
authors.lastname: Atzeni
authors.affiliation: Unit of Dermatology, NESMOS Department, "Sapienza" University of Rome, Italy. Electronic address: alessandra.narcisi@uniroma1.it.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Narcisi
authors.affiliation: Department of Medical-Surgical Critical Area, Section of Clinical, Preventive and Oncological Dermatology, University of Florence, Italy. Electronic address: federicaricceri@hotmail.it.
authors.forename: Federica
authors.initials: F
authors.lastname: Ricceri
authors.affiliation: Rheumatology Unit, L. Sacco University Hospital, Milan, Italy. Electronic address: piercarlo.sarziputtini@gmail.com.
authors.forename: Piercarlo
authors.initials: P
authors.lastname: Sarzi-Puttini
mesh_terms: D002318:Cardiovascular Diseases / Q000150:complications; D006801:Humans; D024821:Metabolic Syndrome / Q000150:complications; D009765:Obesity / Q000150:complications; D011565:Psoriasis / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D011788:Quality of Life; D012307:Risk Factors
keywords: Cardiovascular; Comorbidities; Metabolic syndrome; Outcome measures; Psoriasis; Psoriatic arthritis