title: 11C-Choline and 18F-FDG PET/CT in the Detection of Occult Prostate Cancer in the Context of a Paraneoplastic Syndrome.
abstract: In a 73-year-old man, an occult neoplasm was suspected after 2 consecutive deep venous thrombosis, the latter under anticoagulant therapy and previous axonopathy. After normal CT and MRI findings, a requested (18)F-FDG PET/CT showed a focal uptake in the prostate. Because FDG uptake in the prostate is infrequent, a (11)C-choline PET/CT was indicated revealing a focal uptake in the same location. No other abnormalities were detected in the rest of the body. A guided biopsy by ultrasonography was performed revealing a prostate carcinoma and inflammation in both prostatic lobes.
authors.affiliation: From the Department of Nuclear Medicine, Marqués de Valdecilla University Hospital, University of Cantabria, Santander, Spain.
authors.forename: Julio
authors.initials: J
authors.lastname: Jiménez-Bonilla
authors.forename: Remedios
authors.initials: R
authors.lastname: Quirce
authors.forename: Ignacio
authors.initials: I
authors.lastname: Banzo
authors.forename: Isabel
authors.initials: I
authors.lastname: Martínez-Rodríguez
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Carril
mesh_terms: D000368:Aged; D002250:Carbon Radioisotopes; D002794:Choline; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D064847:Multimodal Imaging; D009382:Neoplasms, Unknown Primary / Q000000981:diagnostic imaging*; D010257:Paraneoplastic Syndromes / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D002250:Carbon Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D002794:Choline