title: [The dynamics of hormonal indicators in women of Arkhangelsk under stimulation of corticotropine].
abstract: The test with pharmaceutical "Synachten Depot", a synthetic analogue of corticotropine was carried out. The sampling consisted of 30 clinically healthy women aged from 20 to 30 years and residents of Arkhangelsk. The scheme of blood sampling provided basal sample, 30 and 60 minutes, I and 4 days after administration of pharmaceutical. After 30 minutes of testing, increase of level of cortisol (F), progesterone (Δ4 = p), testosterone, triiodothyronine (T3) and decreasing of level of insulin and follitropin were established After 60 minutes of testing maximal level of cortisol, high concentration of progesterone and triiodothyronine, increasing of levels of testosterone, estradiol and insulin and decrease of concentration of thyrotropin and prolactin were observed. Up to the first day, the tests registered decrease of level of cortisol, progesterone, testosterone, thyrotropin, thyroxine and triiodothyronine under increasing of content of follitropin, estradiol and insulin in comparison with basal test. Up to the fourth day, tendency of increasing of the level of progesterone and estradiol and decreasing of lutropin and testosterone as compared with initial levels were observed.
authors.forename: E V
authors.initials: EV
authors.lastname: Tipisova
authors.forename: L P
authors.initials: LP
authors.lastname: Poskotinova
authors.forename: I V
authors.initials: IV
authors.lastname: Dvoriashina
authors.forename: E V
authors.initials: EV
authors.lastname: Vereschiagina
authors.forename: N B
authors.initials: NB
authors.lastname: Poliarush
authors.forename: A V
authors.initials: AV
authors.lastname: Vilegjanina
authors.forename: A N
authors.initials: AN
authors.lastname: Zolkina
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage*; D000328:Adult; D003366:Cosyntropin / Q000008:administration & dosage*; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D012426:Russia; D013739:Testosterone / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D007328:Insulin; D014284:Triiodothyronine; D003366:Cosyntropin; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol; C006418:adrenocorticotropin zinc; D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D013972:Thyrotropin; D013974:Thyroxine