title: Linking classification and therapeutic management of vasculitides.
abstract: Vasculitides are classified by the size, type and location of the predominantly involved vessels and by their primary or secondary nature. Their treatment depends on the type of vasculitis, its etiology (when known), and its severity and must be further adjusted by the individual characteristics and comorbidities of patients. In this paper, we review how the classification and definition of vasculitides have evolved over the past years and how it has affected therapeutic changes. As new genetic markers are being discovered and the pathogenesis of vasculitides continues to be elucidated, further modifications in classification and treatment can be expected.
authors.affiliation: Division of Rheumatology, Department of Medicine, University of British Columbia, 1200 Burrard Street, Vancouver, BC, V6Z 2C7, Canada. corrie.baldwin@gmail.com.|Division of Rheumatology, Department of Medicine, Mount Sinai Hospital, 60 Murray Street, Toronto, Ontario, M5T 3L9, Canada. corrie.baldwin@gmail.com.
authors.forename: Corisande
authors.initials: C
authors.lastname: Baldwin
authors.affiliation: Division of Rheumatology, Department of Medicine, Mount Sinai Hospital, 60 Murray Street, Toronto, Ontario, M5T 3L9, Canada. simon.carette@uhn.ca.
authors.forename: Simon
authors.initials: S
authors.lastname: Carette
authors.affiliation: Division of Rheumatology, Department of Medicine, Mount Sinai Hospital, 60 Murray Street, Toronto, Ontario, M5T 3L9, Canada. cpagnoux@mtsinai.on.ca.
authors.forename: Christian
authors.initials: C
authors.lastname: Pagnoux
mesh_terms: D006801:Humans; D014657:Vasculitis / Q000145:classification* / Q000628:therapy*