title: Comparison of health-related quality-of-life measurement instruments in diabetic patients.
abstract: The objective of the study was to compare three different questionnaires (Short Form (SF)-6D, EuroQuol (EQ)-5D and WHO-5) to establish which one is more sensitive and which one gives an adequate assessment of the quality of life in patients with diabetes. In an observational and transversal study with duration of 4 months, in 5 Bulgarian cities, 146 patients were randomly selected. The following quality-of-life measuring instruments were applied: 146 questionnaires SF-6D, 146 questionnaires EQ-5D and 103 questionnaires of WHO-5. Descriptive statistics, chi-Square and correlation coefficients were used for data analysis. The study assessed the quality of life of patients suffering from diabetes mellitus with a mean age of 57.39 years (standard deviation (SD) 17.087); 95% confidence interval (CI) 54.60-60.19; 76% of the patients had diabetes type 2. The patients received a mean SF-6D score of 0.6290, an EQ-5D score of 0.6272, a visual analogue scale score of 0.7158 and a WHO-5 score of 0.4635. Preferences measured by the SF-6D and by the EQ-5D showed significant correlations with one another, and the Pearson coefficient wasr= 0.906 (p< 0.01). The most current version of SF-6D, based on the 2002 model, was found to be valid and reliable when compared to the EQ-5D and is a questionnaire alternative to assess preferences in economic analysis carried out in health care.
authors.affiliation: Department of Social Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
authors.forename: Stanislava
authors.initials: S
authors.lastname: Yordanova
authors.affiliation: Department of Social Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
authors.forename: Valentina
authors.initials: V
authors.lastname: Petkova
authors.affiliation: Department of Social Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
authors.forename: Guenka
authors.initials: G
authors.lastname: Petrova
authors.affiliation: Department of Social Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
authors.forename: Milen
authors.initials: M
authors.lastname: Dimitrov
authors.affiliation: Department of Health Economics, Faculty of Public Health, Medical University of Sofia , Sofia , Bulgaria.
authors.forename: Emilia
authors.initials: E
authors.lastname: Naseva
authors.affiliation: Department of Social Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
authors.forename: Maria
authors.initials: M
authors.lastname: Dimitrova
authors.affiliation: Department of Social Pharmacy, Faculty of Pharmacy, Medical University of Sofia , Sofia , Bulgaria.
authors.forename: Elina
authors.initials: E
authors.lastname: Petkova
keywords: EQ-5D; SF-6D; WHO-5; diabetes mellitus; health-related quality of life