title: Female sexual function and depression after kidney transplantation: comparison between deceased- and living-donor recipients.
abstract: Disturbances in sexual function and depression are a common feature in women with chronic renal failure. Living-donor kidney transplantation seems to warrant better results than its cadaveric counterpart in many aspects but its impact on post-transplantation sexual function remains unknown. This study aimed to compare post-transplantation sexual function and depression in women receiving kidney grafts from living and deceased donors. From a single-center prospective database of 2016 renal transplantations between June 2011 and June 2013, we enrolled 50 sexually active women after kidney transplantation. Female sexual function was evaluated with the Female Sexual Function Index Questionnaire (FSFI) and depression was assessed using the Beck Depression Inventory-II (BDI-II) scale. Thirty-four patients referred the questionnaires. The sexual domains of satisfaction and desire were significantly better in living-donor receptors; in all other domains evaluated by FSFI no statistically significant difference was encountered between groups, although living-donor receptors tended to report better function. Total BDI-II was well correlated with total FSFI score in our study cohort (Spearman's rho = -0.80, P < .001). Only 34.6% of women referred to have discussed sexual issues with their physicians before transplantation, whereas 73.1% stated it would have been important. In conclusion, living-donor transplantation exerted a positive effect on women's sexual function.
authors.affiliation: Department of Urology, Hospital de Santo António, C.H.P, Portugal. Electronic address: joaoferreiracabral@gmail.com.
authors.forename: J F
authors.initials: JF
authors.lastname: Cabral
authors.affiliation: Department of Urology, Hospital de Santo António, C.H.P, Portugal.
authors.forename: V
authors.initials: V
authors.lastname: Cavadas
authors.affiliation: Department of Urology, Hospital de Santo António, C.H.P, Portugal.
authors.forename: M
authors.initials: M
authors.lastname: Silva Ramos
authors.affiliation: Department of Urology, Hospital de Santo António, C.H.P, Portugal.
authors.forename: A
authors.initials: A
authors.lastname: Fraga
authors.affiliation: Department of Nephrology, Hospital de Santo António, C.H.P, Portugal.
authors.forename: M
authors.initials: M
authors.lastname: La Salete Martins
authors.affiliation: Department of Nephrology, Hospital de Santo António, C.H.P, Portugal.
authors.forename: A
authors.initials: A
authors.lastname: Rocha
authors.affiliation: Department of Nephrology, Hospital de S. Teotónio, CHTV, Portugal.
authors.forename: J
authors.initials: J
authors.lastname: Vidinha
authors.affiliation: Department of Urology, Hospital de Santo António, C.H.P, Portugal.
authors.forename: F
authors.initials: F
authors.lastname: Branco
mesh_terms: D000328:Adult; D000368:Aged; D003863:Depression / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000523:psychology; D019520:Living Donors; D008875:Middle Aged; D011174:Portugal / Q000453:epidemiology; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012725:Sexual Behavior / Q000502:physiology*; D011795:Surveys and Questionnaires; D055815:Young Adult