title: Screening of polysaccharides from tamarind, fenugreek and jackfruit seeds as pharmaceutical excipients.
abstract: The paper describes the isolation and screening of plant polysaccharides namely tamarind seed polysaccharide (TSP), fenugreek seed mucilage (FSM) and jackfruit seed starch (JFSS) from tamarind (Tamarindus indica L.) seeds, fenugreek (Trigonella foenum-graecum L.) seeds and jackfruit (Artocarpus heterophyllus L.) seeds, respectively. The yields of isolated dried TSP, FSM and JFSS were 47.00%, 17.36% and 18.86%, respectively. Various physicochemical properties like colour, odour, taste, solubility in water, pH and viscosity of these isolated plant polysaccharides were assessed. Isolated polysaccharide samples were subjected to some phytochemical identification tests. FTIR and (1)H NMR analyses of isolated polysaccharides were performed, which suggest the presence of sugar residues. Isolated TSP, FSM and JFSS can be used as pharmaceutical excipients in various pharmaceutical formulations.
authors.affiliation: Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Sciences, Mayurbhanj 757086, Odisha, India. Electronic address: amitkrnayak@yahoo.co.in.
authors.forename: Amit Kumar
authors.initials: AK
authors.lastname: Nayak
authors.affiliation: Department of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Koni, Bilaspur 495 009, C.G., India.
authors.forename: Dilipkumar
authors.initials: D
authors.lastname: Pal
authors.affiliation: Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Sciences, Mayurbhanj 757086, Odisha, India.
authors.forename: Kousik
authors.initials: K
authors.lastname: Santra
mesh_terms: D000268:Adhesiveness; D031622:Artocarpus / Q000737:chemistry*; D003116:Color; D005079:Excipients / Q000737:chemistry* / Q000302:isolation & purification; D006863:Hydrogen-Ion Concentration; D009812:Odorants; D011134:Polysaccharides / Q000737:chemistry* / Q000302:isolation & purification; D012639:Seeds / Q000737:chemistry*; D012995:Solubility; D029861:Tamarindus / Q000737:chemistry*; D029910:Trigonella / Q000737:chemistry*; D014783:Viscosity
chemical_list: D005079:Excipients; D011134:Polysaccharides
keywords: Fenugreek seed mucilage; Jackfruit seed starch; Tamarind seed polysaccharide