title: [Synchronous multicentric osteosarcoma: with multiple primary tumors or metastatic disease. Report of one case and literature review].
abstract: Synchronous multicentric osteosarcoma, is a tumor with presentation in two or more sites without the appearance of lung metastasis. The incidence is 1 to 3% of all osteosarcomas and only less than 100 cases have been documented in the literature. In our case, we are presenting a six and a half year old patient with a painful tumor in the left thigh diagnosed with an incisional biopsy that reported a high grade conventional osteosarcoma in the left distal femur, a lesion in the contralateral limb in distal femur and proximal tibia, with no favorable response to chemotherapy. Lung and brain metastases were detected; therefore, we decided to give multidisciplinary palliative care for the disease. Years after its description there is still debate whether this condition really corresponds to a primary variable or to a manifestation of the metastatic disease.
authors.forename: L A
authors.initials: LA
authors.lastname: Rossier-Guillot
authors.forename: R
authors.initials: R
authors.lastname: Tecualt-Gómez
authors.forename: R
authors.initials: R
authors.lastname: Amaya-Cepeda
authors.forename: M I
authors.initials: MI
authors.lastname: Barrera-García
mesh_terms: D001859:Bone Neoplasms / Q000175:diagnosis / Q000628:therapy; D002648:Child; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000628:therapy; D012516:Osteosarcoma / Q000175:diagnosis / Q000556:secondary / Q000628:therapy