title: Health risk assessment of heavy metals and metalloid in drinking water from communities near gold mines in Tarkwa, Ghana.
abstract: Concentrations of heavy metals and metalloid in borehole drinking water from 18 communities in Tarkwa, Ghana, were measured to assess the health risk associated with its consumption. Mean concentrations of heavy metals (μg/L) exceeded recommended values in some communities. If we take into consideration the additive effect of heavy metals and metalloid, then oral hazard index (HI) results raise concerns about the noncarcinogenic adverse health effects of drinking groundwater in Huniso. According to the US Environmental Protection Agency's (USEPA) guidelines, HI values indicating noncarcinogenic health risk for adults and children in Huniso were 0.781 (low risk) and 1.08 (medium risk), respectively. The cancer risk due to cadmium (Cd) exposure in adults and children in the sampled communities was very low. However, the average risk values of arsenic (As) for adults and children through drinking borehole water in the communities indicated medium cancer risk, but high cancer risk in some communities such as Samahu and Mile 7. Based on the USEPA assessment, the average cancer risk values of As for adults (3.65E-05) and children (5.08E-05) indicated three (adults) and five (children) cases of neoplasm in a hundred thousand inhabitants. The results of this study showed that residents in Tarkwa who use and drink water from boreholes could be at serious risk from exposure to these heavy metals and metalloid.
authors.affiliation: Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita ku, Sapporo, 060-0818, Japan.
authors.forename: Nesta
authors.initials: N
authors.lastname: Bortey-Sam
authors.forename: Shouta M M
authors.initials: SM
authors.lastname: Nakayama
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Ikenaka
authors.forename: Osei
authors.initials: O
authors.lastname: Akoto
authors.forename: Elvis
authors.initials: E
authors.lastname: Baidoo
authors.forename: Hazuki
authors.initials: H
authors.lastname: Mizukawa
authors.forename: Mayumi
authors.initials: M
authors.lastname: Ishizuka
mesh_terms: D000328:Adult; D001151:Arsenic / Q000032:analysis / Q000633:toxicity*; D002648:Child; D060766:Drinking Water / Q000009:adverse effects* / Q000032:analysis; D004784:Environmental Monitoring; D005869:Ghana; D006046:Gold; D060587:Groundwater / Q000032:analysis; D006801:Humans; D019216:Metals, Heavy / Q000032:analysis / Q000633:toxicity*; D008906:Mining; D018570:Risk Assessment; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*
chemical_list: D060766:Drinking Water; D019216:Metals, Heavy; D014874:Water Pollutants, Chemical; D006046:Gold; D001151:Arsenic