title: Involvement of fish immunomarkers in environmental biomonitoring approach: Urban and agri-viticultural context.
abstract: The Champagne region (France) is characterized by various chemical environmental pressures which could interfere with the immune status of natural populations of European bullhead, Cottus sp. Some adult fish were caught by electrofishing in spring, summer and autumn to determined immune effect of urban (Muizon), intensive agricultural (Bouy; Prunay) or viticultural (Serzy; Prunay) influences. The major results demonstrated an increase of cellular mortality and a decrease of phagocytosis activity in the stations impacted by agri-viticultural chemicals. These immunomodulations followed the temporal variability due to different treatments (agricultural impacts on spring; viticultural effects on autumn). At the present time, not enough data was provided to confirm the impact of agri-viticultural chemicals on fish immune system without interaction with other environmental factors. For example, in summer, the immunomarkers seems to be not only correlated with water contamination but also with other environmental factors (pathogens, physical field degradation, nutrients, temperature …). Nevertheless, immune parameters give a global view of organism and ecosystem health explaining growing interest for these biomarkers in environmental risk assessment.
authors.affiliation: UMR-I 02 (INERIS, URCA, ULH) SEBIO Stress environnementaux et Biosurveillance des milieux aquatiques, Université Reims Champagne-Ardenne (URCA), UFR Sciences Exactes et Naturelles, Moulin de la Housse, B.P. 1039, 51687 Reims, France; UMR-I 02 SEBIO, Institut National de l'Environnement Industriel et des Risques (INERIS), B.P. 2, 60550 Verneuil-en-Halatte, France. Electronic address: anne.bado-nilles@ineris.fr.
authors.forename: Anne
authors.initials: A
authors.lastname: Bado-Nilles
authors.affiliation: UMR-I 02 (INERIS, URCA, ULH) SEBIO Stress environnementaux et Biosurveillance des milieux aquatiques, Université Reims Champagne-Ardenne (URCA), UFR Sciences Exactes et Naturelles, Moulin de la Housse, B.P. 1039, 51687 Reims, France; UMR-I 02 SEBIO, Institut National de l'Environnement Industriel et des Risques (INERIS), B.P. 2, 60550 Verneuil-en-Halatte, France. Electronic address: sabrina.jolly@univ-reims.fr.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Jolly
authors.affiliation: Office National de l'Eau et des Milieux Aquatiques (ONEMA), Délégation Inter-Régionale Nord-Est, 57155 Marly, France. Electronic address: florent.lamand@onema.fr.
authors.forename: Florent
authors.initials: F
authors.lastname: Lamand
authors.affiliation: UMR-I 02 (INERIS, URCA, ULH) SEBIO Stress environnementaux et Biosurveillance des milieux aquatiques, Université Reims Champagne-Ardenne (URCA), UFR Sciences Exactes et Naturelles, Moulin de la Housse, B.P. 1039, 51687 Reims, France. Electronic address: alain.geffard@univ-reims.fr.
authors.forename: Alain
authors.initials: A
authors.lastname: Geffard
authors.affiliation: Institut de Radioprotection et de Sureté Nucléaire (IRSN), PRP-ENV/SERIS/LECO, Centre de Cadarache, Bât 186, B.P. 3, 13115 Saint-Paul-lez-Durance, France. Electronic address: beatrice.gagnaire@irsn.fr.
authors.forename: Béatrice
authors.initials: B
authors.lastname: Gagnaire
authors.affiliation: UMR-I 02 SEBIO, Institut National de l'Environnement Industriel et des Risques (INERIS), B.P. 2, 60550 Verneuil-en-Halatte, France. Electronic address: cyril.turies@ineris.fr.
authors.forename: Cyril
authors.initials: C
authors.lastname: Turies
authors.affiliation: UMR-I 02 SEBIO, Institut National de l'Environnement Industriel et des Risques (INERIS), B.P. 2, 60550 Verneuil-en-Halatte, France. Electronic address: jean-marc.porcher@ineris.fr.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Porcher
authors.affiliation: UMR-I 02 SEBIO, Institut National de l'Environnement Industriel et des Risques (INERIS), B.P. 2, 60550 Verneuil-en-Halatte, France. Electronic address: wilfried.sanchez@ineris.fr.
authors.forename: Wilfried
authors.initials: W
authors.lastname: Sanchez
authors.affiliation: UMR-I 02 (INERIS, URCA, ULH) SEBIO Stress environnementaux et Biosurveillance des milieux aquatiques, Université Reims Champagne-Ardenne (URCA), UFR Sciences Exactes et Naturelles, Moulin de la Housse, B.P. 1039, 51687 Reims, France. Electronic address: stephane.betoulle@univ-reims.fr.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Betoulle
mesh_terms: D000383:Agriculture; D000818:Animals; D015415:Biomarkers; D017753:Ecosystem; D004777:Environment; D004784:Environmental Monitoring / Q000379:methods*; D005399:Fishes / Q000276:immunology*; D005602:France; D010473:Perciformes / Q000276:immunology*; D018570:Risk Assessment; D012621:Seasons; D014876:Water Pollution
chemical_list: D015415:Biomarkers
keywords: Agri-viticultural pressures; Biomonitoring; Fish; Immunotoxicology; Pathogen.; Urban pressure