title: Primary herpes simplex virus infection mimicking cervical cancer.
abstract: We report the case of an 18-year-old woman presenting with ulceration of the cervix caused by primary type 2 herpes simplex infection in the absence of skin lesions. The differential diagnosis included cervical cancer and we referred the patient for urgent colposcopy. However, laboratory tests proved the viral aetiology of the cervical ulceration and the cervix had healed completely 3 weeks later. The case highlights the need to consider herpes simplex infection in the differential diagnosis of ulceration of the cervix even when there are no cutaneous signs of herpes.
authors.affiliation: Department of Sexual Health, Pennine Acute Hos NHS Trust, Manchester, UK.
authors.forename: Andrew
authors.initials: A
authors.lastname: Tomkins
authors.affiliation: Department of Sexual Health, Pennine Acute Hos NHS Trust, Manchester, UK.
authors.forename: Catherine
authors.initials: C
authors.lastname: White
authors.affiliation: Department of Sexual Health, Pennine Acute Hos NHS Trust, Manchester, UK.
authors.forename: Stephen Peter
authors.initials: SP
authors.lastname: Higgins
mesh_terms: D000293:Adolescent; D003127:Colposcopy / Q000379:methods; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006558:Herpes Genitalis / Q000175:diagnosis / Q000473:pathology / Q000821:virology; D006561:Herpes Simplex / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D018139:Simplexvirus / Q000235:genetics / Q000302:isolation & purification*; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology