title: Stereoselective synthesis of epoxyisoprostanes: an organocatalytic and "pot-economy" approach.
abstract: An efficient and direct synthetic route to epoxyisoprostane EC methyl ester has been accomplished in 8 steps (10% overall yield) from readily available starting materials using a series of asymmetric organocatalytic reactions and one-pot operations.
authors.affiliation: Institute of Medicinal Chemistry, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, People's Republic of China. wengj2@mail.sysu.edu.cn lugui@mail.sysu.edu.cn.
authors.forename: Jiang
authors.initials: J
authors.lastname: Weng
authors.forename: Sheng
authors.initials: S
authors.lastname: Wang
authors.forename: Lin-Jie
authors.initials: LJ
authors.lastname: Huang
authors.forename: Zhang-Yi
authors.initials: ZY
authors.lastname: Luo
authors.forename: Gui
authors.initials: G
authors.lastname: Lu
mesh_terms: D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D004852:Epoxy Compounds / Q000737:chemistry*; D028421:Isoprostanes / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004852:Epoxy Compounds; D028421:Isoprostanes