title: Psychometric validation of the Brief Pain Inventory-Short Form in patients with systemic lupus erythematosus in the United States.
abstract: This study evaluated the Brief Pain Inventory-Short Form (BPI-SF) in patients with moderate-to-severe systemic lupus erythematosus (SLE). Patients ≥18 years old who self-reported a physician diagnosis of SLE (confirmed by medical record review) and active SLE (Systemic Lupus Activity Questionnaire (SLAQ) score of ≥11) were included. The BPI-SF and Short Form Health Survey version 2 (SF-36v2) were administered electronically at baseline, week 2 and week 12. Psychometric properties of the BPI-SF were evaluated. Cronbach alphas were >0.9 for all BPI-SF items, domains and total score. Test-retest reliability correlations for responses between baseline and week 2 of the BPI-SF had intraclass correlation coefficients (ICCs) ≥0.5. The BPI-SF domains and total score were moderately positively correlated to the SLAQ score (r ≥ 0.4), but negatively correlated to the SF-36v2 bodily pain domain (r ≤ -0.6). The BPI-SF domains and total score were moderately negatively correlated to the SF-36v2 physical functioning domain and physical component summary (r ≤ -0.4), with low correlations between the BPI-SF severity domain and SF-36v2 mental component summary (r = -0.16). Assessment of pain, as measured by the BPI-SF, demonstrated validity and reliability in a sample of patients with moderate-to-severe SLE.
authors.affiliation: Global Patient Outcomes and Real World Evidence, Eli Lilly and Company, Indianapolis, IN, USA naegelian@lilly.com.
authors.forename: A N
authors.initials: AN
authors.lastname: Naegeli
authors.affiliation: Quintiles, Rockville, MD, USA.
authors.forename: E L
authors.initials: EL
authors.lastname: Tomaszewski
authors.affiliation: Global Patient Outcomes and Real World Evidence, Eli Lilly and Company, Indianapolis, IN, USA.
authors.forename: S
authors.initials: S
authors.lastname: Al Sawah
mesh_terms: D000328:Adult; D003710:Demography; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000145:classification / Q000175:diagnosis / Q000209:etiology / Q000523:psychology*; D010147:Pain Measurement / Q000379:methods*; D011594:Psychometrics / Q000379:methods*; D011788:Quality of Life; D015203:Reproducibility of Results; D057566:Self Report; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D014481:United States
keywords: Brief Pain Inventory-Short Form; pain; patient-reported outcome; reliability; systemic lupus erythematosus; validity