title: Robotic-assisted Laparoscopic Management of Chemoresistant Myoinvasive Complete Molar Pregnancy.
abstract: Postmolar malignant conditions are rare after evacuation of a complete molar pregnancy. Both medical and surgical management have a role in the treatment of persistent gestational trophoblastic neoplasia. Treatment decisions must account for the natural history of the disease, previous therapies, site of disease, and the patient's desire for uterine preservation. We report on a woman who presented with chemotherapy-refractory persistent gestational trophoblastic disease (GTD). She was found to have isolated, persistent trophoblastic tissue within the uterine myometrium. She underwent a robotic-assisted laparoscopic hysterectomy with curative results. Minimally invasive surgical management may be an option for treatment of women with isolated myoinvasive GTD.
authors.affiliation: Divisions of Minimally Invasive Gynecologic Surgery and Gynecologic Oncology, Department of Obstetrics and Gynecology, Penn State Hershey Medical Center, Hershey, Pennsylvania. Electronic address: Kriley1@hmc.psu.edu.
authors.forename: Kristin
authors.initials: K
authors.lastname: Riley
authors.affiliation: Department of Pathology, Penn State Hershey Medical Center, Hershey, Pennsylvania.
authors.forename: Jordan
authors.initials: J
authors.lastname: Newell
authors.affiliation: Department of Pathology, Penn State Hershey Medical Center, Hershey, Pennsylvania.
authors.forename: Richard
authors.initials: R
authors.lastname: Zaino
authors.affiliation: Divisions of Minimally Invasive Gynecologic Surgery and Gynecologic Oncology, Department of Obstetrics and Gynecology, Penn State Hershey Medical Center, Hershey, Pennsylvania.
authors.forename: Joshua
authors.initials: J
authors.lastname: Kesterson
mesh_terms: D000328:Adult; D005260:Female; D031901:Gestational Trophoblastic Disease / Q000150:complications / Q000473:pathology*; D006801:Humans; D006828:Hydatidiform Mole / Q000473:pathology / Q000601:surgery; D007044:Hysterectomy / Q000379:methods; D010535:Laparoscopy; D009215:Myometrium / Q000473:pathology* / Q000601:surgery; D011247:Pregnancy; D065287:Robotic Surgical Procedures; D016896:Treatment Outcome; D014328:Trophoblastic Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D014594:Uterine Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*
keywords: Gestational trophoblastic disease; Hysterectomy; Laparoscopy; Robotic surgical procedures