title: [New drugs for small animals in 2014].
abstract: In 2014, six active pharmaceutical ingredients were released on the German market for small animals. Those are the ektoparasiticide of the isoxazoline group afoxolaner (NexGard®) and fluralaner (Bravecto®) and the neonicotinoid dinotefuran (Vectra 3D, Vectra Felis), the antidiabetic protamine zinc insulin of human origin (ProZinc®), the antifungal agent ketoconazole (Fugazid®) as well as the cytostatic drug oclacitinib (Apoquel®). Two substances were authorized for an additional species. The antiparasiticide eprinomectin and the antibiotic clindamycin were also authorized for use in cats. In addition, two active pharmaceutical ingredients, which were approved 2014 for use in human medicine and are of potential interest to veterinary medicine, are discussed. These are the antihypertensive drug riociguat and the urological substance mirabegron.
authors.affiliation: Dr. Ilka Ute Emmerich, VETIDATA, Institut für Pharmakologie, Pharmazie und Toxikologie, Veterinärmedizinische Fakultät, Universität Leipzig, An den Tierkliniken 39, 04103 Leipzig, E-Mail: emmerich@vetmed.uni-leipzig.de.
authors.forename: I U
authors.initials: IU
authors.lastname: Emmerich
mesh_terms: D000818:Animals; D002415:Cats; D004285:Dogs; D006146:Guanidines; D007328:Insulin; D007555:Isoxazoles; D007654:Ketoconazole; D009281:Naphthalenes; D000073943:Neonicotinoids; D009574:Nitro Compounds; D011743:Pyrimidines; D013449:Sulfonamides; D019155:Veterinary Drugs
chemical_list: C000591860:A1443 compound; D006146:Guanidines; D007328:Insulin; D007555:Isoxazoles; D009281:Naphthalenes; D000073943:Neonicotinoids; D009574:Nitro Compounds; D011743:Pyrimidines; D013449:Sulfonamides; D019155:Veterinary Drugs; C000589002:afoxolaner; C465368:dinotefuran; C588062:oclacitinib; D007654:Ketoconazole
keywords: Drugs; afoxolaner; cats; dinotefuran; dogs; fluralaner; human insulin; ketoconazole; oclacitinib; registration