title: Angiosarcoma: A rare malignancy with protean clinical presentations.
abstract: Angiosarcoma is a rare form of soft tissue sarcoma. Primary small intestinal angiosarcomas are especially uncommon. The clinical presentations of small intestinal angiosarcomas vary but gastrointestinal (GI) bleeding is a frequent finding. We present a case of persistent GI bleeding of unknown etiology culminating in operative exploration demonstrating a primary small intestinal angiosarcoma. A discussion of the diagnosis, pathology, and management of angiosarcoma with a review of the current literature is provided including molecular genetics, difficult cases, and current treatment options.
authors.affiliation: Department of General Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio.
authors.forename: Justin T
authors.initials: JT
authors.lastname: Huntington
authors.affiliation: Department of Surgery, Division of Trauma, Critical Care and Burn, The Ohio State University Wexner Medical Center, Columbus, Ohio.
authors.forename: Christian
authors.initials: C
authors.lastname: Jones
authors.affiliation: Division of Medical Oncology, The Ohio State University Wexner Medical Center, Columbus, Ohio.|Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio.
authors.forename: David A
authors.initials: DA
authors.lastname: Liebner
authors.affiliation: Division of Medical Oncology, The Ohio State University Wexner Medical Center, Columbus, Ohio.|Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio.
authors.forename: James L
authors.initials: JL
authors.lastname: Chen
authors.affiliation: Department of Surgery, Division of Surgical Oncology, The Ohio State University Wexner Medical Center - James Cancer Hospital and Solove Research Institute, Columbus, Ohio.
authors.forename: Raphael E
authors.initials: RE
authors.lastname: Pollock
mesh_terms: D000368:Aged; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D006801:Humans; D007078:Ileal Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D008297:Male
keywords: angiosarcoma; gastrointestinal bleeding; sarcoma; small bowel bleeding