title: Implementation of a standardised method for the production of allogeneic serum eye drops from regular blood donors in a Norwegian University Hospital: Some methodological aspects and clinical considerations.
abstract: The use of autologous serum eye drops has been shown to be effective for the treatment of many ocular diseases. For patients were repeated blood sampling is not possible, allogeneic serum eye drops have been shown to be an effective and safe alternative. In our institution, we have managed to produce allogeneic serum eye drops from regular blood donors using a standardised procedure. The effectiveness and safety of this product will be evaluated in a clinical trial.
authors.affiliation: Department of Immunology and Transfusion Medicine, St. Olav's Hospital, Trondheim, Norway.
authors.forename: A
authors.initials: A
authors.lastname: Espinosa
authors.affiliation: Hematology Department, St. Olav's Hospital, Trondheim, Norway.
authors.forename: H
authors.initials: H
authors.lastname: Hjorth-Hansen
authors.affiliation: Ophthalmological Department, St. Olav's Hospital, Trondheim, Norway.
authors.forename: K
authors.initials: K
authors.lastname: Aasly
authors.affiliation: Department of Immunology and Transfusion Medicine, St. Olav's Hospital, Trondheim, Norway.
authors.forename: I
authors.initials: I
authors.lastname: Teigum
authors.affiliation: Hospital Pharmacy, Trondheim, Norway.
authors.forename: G
authors.initials: G
authors.lastname: Sivertsen
authors.affiliation: International Consultancy in Blood Component Quality/Safety Improvement, Audit/Inspection & DDR Strategy, London, UK. Electronic address: jseghatchian@btopenworld.com.
authors.forename: J
authors.initials: J
authors.lastname: Seghatchian
mesh_terms: D001782:Blood Donors; D015352:Dry Eye Syndromes / Q000188:drug therapy*; D005260:Female; D006785:Hospitals, University; D006801:Humans; D008297:Male; D009664:Norway; D009883:Ophthalmic Solutions / Q000737:chemistry / Q000627:therapeutic use; D044967:Serum / Q000737:chemistry*
chemical_list: D009883:Ophthalmic Solutions