title: [Modification of health-related quality of life in kidney transplant recipients].
abstract: BACKGROUND
  The assessment of health-related quality of life is essential to renal replacement therapies. We conducted a study to evaluate the change in quality of life at 6 and 12 months after renal transplantation and compared with healthy population and general population.
  
  
  METHODS
  A prospective study in 278 renal transplant recipients using the SF-36 survey at 0, 6 and 12 months after transplantation. The results were compared with those obtained in healthy population (kidney donors) and general population. Student t test was employed for comparisons of means. A value of p<0.05 was considered statistically significant.
  
  
  RESULTS
  The quality of life before transplantation was lower than that observed in healthy population and the general population (p<0.001). At 6 months of transplantation significant improvement over the baseline measurement (p<0.001) in the 8 domains and the two composite scales was obtained, but at 12 months, an additional benefit was not observed. The quality of life of recipients at 12 months of transplant was lower only in the concept of general health (p=0.035) compared with healthy population. However, it was higher than general population in physical and mental composite scales (p=0.013 and p=0.001 respectively).
  
  
  CONCLUSIONS
  The health related quality of life improved significantly at 6 and 12 months after renal transplantation, achieving equated healthy population and general population.
authors.affiliation: Unidad de Trasplantes, Hospital de Especialidades, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Distrito Federal. luis.enrique.alvarez.rangel@gmail.com.
authors.forename: Luis Enrique
authors.initials: LE
authors.lastname: Álvarez-Rangel
authors.forename: José
authors.initials: J
authors.lastname: Cruz-Santiago
authors.forename: Guillermo
authors.initials: G
authors.lastname: Meza-Jiménez
authors.forename: Germán
authors.initials: G
authors.lastname: Bernáldez-Gómez
authors.forename: Víctor Manuel
authors.initials: VM
authors.lastname: Ledesma-González
authors.forename: Fernando
authors.initials: F
authors.lastname: Camacho-Hernández
authors.forename: Arturo
authors.initials: A
authors.lastname: Rodríguez-Rodríguez
authors.forename: Carolina
authors.initials: C
authors.lastname: Aguilar-Martínez
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005500:Follow-Up Studies; D006305:Health Status Indicators; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011184:Postoperative Period; D011446:Prospective Studies; D011788:Quality of Life
keywords: Health related quality of life; Nephrology; Renal transplant