title: [Effect of a vascular event on drug regimen compliance in patients with coronary atherosclerosis].
abstract: In order to assess the effect of a vascular event on adherence to treatment we examined a total of 68 patients presenting with coronary atherosclerosis. The patients' age varied from 31 to 84 years (mean 57.1±8.7). There were 55 (81.1%) men and 13 (18.9%) women. Drug regimen compliance was evaluated by means of the Morisky-Green Medication Adherence Questionnaire before and after the vascular event. Of the 68 examined patients, 15 (22.1%) had not taken any therapeutic agents before the vascular event occurred, despite existing arterial hypertension. Drug regimen compliance prior to the vascular event was low in 82.4% of cases. The number of patients with coronary atherosclerosis and low compliance to treatment before the vascular event decreased significantly thereafter (p=0.0012). After the vascular event, the number of patients adhering to the doctor's recommendations on medicamentous therapy increases considerably. At the same time, a sufficiently great number of patients [about 30% of patients after endured myocardial infarction (MI) and 18% after transcutaneous coronary intervention (TCI)] still remain in the category of those "having low drug regimen compliance" and, accordingly, have high risk for the development of recurrent vascular events. Endured TCI increases patient compliance more significantly than MI, which requires additional study of a psychological component of the given fact.
authors.affiliation: Department of Propaedeutics of Internal Diseases, Omsk State Medical Academy of the Ministry of Public Health of the Russian Federation, Omsk, Russia.
authors.forename: S S
authors.initials: SS
authors.lastname: Bunova
authors.affiliation: Department of Propaedeutics of Internal Diseases, Omsk State Medical Academy of the Ministry of Public Health of the Russian Federation, Omsk, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Usacheva
authors.affiliation: Department of Propaedeutics of Internal Diseases, Omsk State Medical Academy of the Ministry of Public Health of the Russian Federation, Omsk, Russia.
authors.forename: A Yu
authors.initials: AY
authors.lastname: Ivanov
mesh_terms: D002317:Cardiovascular Agents / Q000627:therapeutic use*; D003324:Coronary Artery Disease / Q000188:drug therapy / Q000209:etiology / Q000523:psychology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy / Q000523:psychology; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy / Q000209:etiology / Q000523:psychology; D020380:Needs Assessment; D010349:Patient Compliance / Q000523:psychology*; D062645:Percutaneous Coronary Intervention / Q000379:methods / Q000523:psychology; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D012426:Russia; D055502:Secondary Prevention / Q000379:methods; D011795:Surveys and Questionnaires
chemical_list: D002317:Cardiovascular Agents; D010975:Platelet Aggregation Inhibitors