title: Determination of dexamethasone by flow-injection chemiluminescence method using capped CdS quantum dots.
abstract: L-Cysteine capped CdS quantum dots (QDs) were synthesized through a facile hydrothermal method and characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), photoluminescence (PL) and UV-Vis spectroscopy. The light emitted from KMnO4-L-cysteine capped CdS QDs reaction in acidic medium was applied as a simple and sensitive chemiluminescence (CL) system for determination of dexamethasone. The CL intensity of KMnO4-L-cysteine capped CdS QDs CL system was remarkably enhanced in the presence of dexamethasone. Under optimum experimental conditions, the enhanced CL intensity was related to dexamethasone concentration in the range of 0.004-25.0 mg L(-1), with the detection limit (3σ) of 0.0013 mg L(-1). The analytical applicability of the proposed CL system was assessed by determining dexamethasone in spiked environmental water samples and pharmaceutical formulation. The analytical performances of proposed flow-injection CL method for the determination of dexamethasone were compared with those obtained by corona discharge ionization ion mobility spectrometry (CD-IMS) method. The proposed CL system exhibits a higher sensitivity and precision than the CD-IMS method for the determination of dexamethasone.
authors.affiliation: Research Laboratory of Advanced Water and Wastewater Treatment Processes, Department of Applied Chemistry, Faculty of Chemistry, University of Tabriz, 51666-16471 Tabriz, Iran. Electronic address: a_khataee@tabrizu.ac.ir.
authors.forename: Alireza
authors.initials: A
authors.lastname: Khataee
authors.affiliation: Research Laboratory of Advanced Water and Wastewater Treatment Processes, Department of Applied Chemistry, Faculty of Chemistry, University of Tabriz, 51666-16471 Tabriz, Iran.
authors.forename: Aliyeh
authors.initials: A
authors.lastname: Hasanzadeh
authors.affiliation: Research Laboratory of Advanced Water and Wastewater Treatment Processes, Department of Applied Chemistry, Faculty of Chemistry, University of Tabriz, 51666-16471 Tabriz, Iran.
authors.forename: Roya
authors.initials: R
authors.lastname: Lotfi
authors.affiliation: Department of Chemistry, Faculty of Science, University of Zanjan, 45371-38791 Zanjan, Iran.
authors.forename: Rahmatollah
authors.initials: R
authors.lastname: Pourata
authors.affiliation: School of Mechanical Engineering, Yeungnam University, 712-749 Gyeongsan, South Korea. Electronic address: swjoo@yu.ac.kr.
authors.forename: Sang Woo
authors.initials: SW
authors.lastname: Joo
mesh_terms: D000893:Anti-Inflammatory Agents / Q000032:analysis*; D019187:Cadmium Compounds / Q000737:chemistry*; D003545:Cysteine / Q000737:chemistry; D003907:Dexamethasone / Q000032:analysis*; D004784:Environmental Monitoring / Q000295:instrumentation; D004867:Equipment Design; D017022:Flow Injection Analysis / Q000295:instrumentation; D057230:Limit of Detection; D049449:Luminescence; D008163:Luminescent Measurements / Q000295:instrumentation*; D045663:Quantum Dots / Q000737:chemistry*; D013440:Sulfides / Q000737:chemistry*; D014867:Water / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D000893:Anti-Inflammatory Agents; D019187:Cadmium Compounds; D013440:Sulfides; D014874:Water Pollutants, Chemical; C034939:cadmium sulfide; D014867:Water; D003907:Dexamethasone; D003545:Cysteine
keywords: CdS quantum dots; Chemiluminescence; Dexamethasone; Flow injection; Nanocatalyst