title: [Chronic leg ulcers and Pseudomonas aeruginosa infection].
abstract: Pseudomonas aeruginosa (PA) is a Gram-negative germ, responsible for severe infections. PA infected chronic wounds are a clinically highly relevant topic. PA has a natural resistance to many antibiotics, and there is no consensus on a first-line antibiotic to be used. In the context of chronic ulcers with an unfavorable evolution, we suggest intravenous antibiotic therapy, ideally on an in-patient basis. Given the sparse evidence from clinical trials, we heavily rely on clinical experience when it comes to managing chronic ulcers infected with PA.
authors.forename: Evangelia
authors.initials: E
authors.lastname: Tzika
authors.forename: Donato
authors.initials: D
authors.lastname: Ferrara
authors.forename: Wolf-Henning
authors.initials: WH
authors.lastname: Boehncke
authors.forename: Laurence Toutous
authors.initials: LT
authors.lastname: Trellu
authors.forename: Neda
authors.initials: N
authors.lastname: Barouti
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002908:Chronic Disease; D024881:Drug Resistance, Bacterial; D006801:Humans; D007871:Leg Ulcer / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents