title: Fujiwara-Moritani Reaction of Weinreb Amides using a Ruthenium-Catalyzed C-H Functionalization Reaction.
abstract: The ruthenium-catalyzed Fujiwara-Moritani reaction (oxidative-Heck reaction) of Weinreb amides is reported herein. The reaction affords exclusively ortho-C-H olefination products, has excellent substrate scope and tolerates halogen functionalities, which increase the synthetic utility of the method. A variety of activated olefins as well as styrenes can be employed as coupling partners.
authors.affiliation: Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Academic Building II, Indore Bypass Road, Bhauri, Bhopal, 462066, MP, India.
authors.forename: Riki
authors.initials: R
authors.lastname: Das
authors.affiliation: Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Academic Building II, Indore Bypass Road, Bhauri, Bhopal, 462066, MP, India. mk@iiserb.ac.in.
authors.forename: Manmohan
authors.initials: M
authors.lastname: Kapur
keywords: C−H functionalization; Fujiwara-Moritani; amides; oxidative Heck; ruthenium