title: Multifunctional inverse opal particles for drug delivery and monitoring.
abstract: Particle-based delivery systems have a demonstrated value for drug discovery and development. Here, we report a new type of particle-based delivery system that has controllable release and is self-monitoring. The particles were composed of poly(N-isopropylacrylamide) (pNIPAM) hydrogel with an inverse opal structure. The presence of macropores in the particles provides channels for active drug loading and release from the materials.
authors.affiliation: State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China. yjzhao@seu.edu.cn gu@seu.edu.cn.
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.forename: Yao
authors.initials: Y
authors.lastname: Cheng
authors.forename: Huan
authors.initials: H
authors.lastname: Wang
authors.forename: Baofen
authors.initials: B
authors.lastname: Ye
authors.forename: Luoran
authors.initials: L
authors.lastname: Shang
authors.forename: Yuanjin
authors.initials: Y
authors.lastname: Zhao
authors.forename: Zhongze
authors.initials: Z
authors.lastname: Gu
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D003287:Contrast Media / Q000138:chemical synthesis*; D003692:Delayed-Action Preparations / Q000138:chemical synthesis*; D004058:Diffusion; D016903:Drug Monitoring / Q000379:methods*; D008856:Microscopy, Fluorescence / Q000379:methods; D053769:Nanocapsules / Q000008:administration & dosage / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D000068936:Theranostic Nanomedicine / Q000379:methods
chemical_list: D000180:Acrylic Resins; D003287:Contrast Media; D003692:Delayed-Action Preparations; D053769:Nanocapsules; C052970:poly-N-isopropylacrylamide