title: Graphene-Based Materials in Regenerative Medicine.
abstract: Graphene possesses many unique properties such as two-dimensional planar structure, super conductivity, chemical and mechanical stability, large surface area, and good biocompatibility. In the past few years, graphene-based materials have risen as a shining star on the path of researchers seeking new materials for future regenerative medicine. Herein, the recent research advances made in graphene-based materials mostly utilizing the mechanical and electrical properties of graphene are described. The most exciting findings addressing the impact of graphene-based materials on regenerative medicine are highlighted, with particular emphasis on their applications including nerve, bone, cartilage, skeletal muscle, cardiac, skin, adipose tissue regeneration, and their effects on the induced pluripotent stem cells. Future perspectives and emerging challenges are also addressed in this Review article.
authors.affiliation: Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, International Research Center for Implantable and Interventional Medical Devices, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, P. R. China.
authors.forename: Xili
authors.initials: X
authors.lastname: Ding
authors.affiliation: Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, International Research Center for Implantable and Interventional Medical Devices, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, P. R. China.
authors.forename: Haifeng
authors.initials: H
authors.lastname: Liu
authors.affiliation: Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, International Research Center for Implantable and Interventional Medical Devices, School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, P. R. China.|National Research Center for Rehabilitation Technical Aids, Beijing, 100176, P. R. China.
authors.forename: Yubo
authors.initials: Y
authors.lastname: Fan
mesh_terms: D001861:Bone Regeneration; D002454:Cell Differentiation; D006108:Graphite / Q000737:chemistry* / Q000633:toxicity; D006801:Humans; D018482:Muscle, Skeletal / Q000502:physiology; D009474:Neurons / Q000502:physiology; D012038:Regeneration; D044968:Regenerative Medicine; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism; D023822:Tissue Engineering
chemical_list: D006108:Graphite
keywords: graphene; regenerative medicine; stem cells; tissue engineering