title: New insight in the treatment of refractory melasma: Laser Q-switched Nd: YAG non-ablative fractionated followed by intense pulsed light.
abstract: The purpose of our study was to verify the results of the association of Q-switched Nd: YAG non-ablative fractionated with intense pulsed light, in order to treat patients with refractory melasma. The combination of these two devices seems to be the best treatment to combat hyperpigmentation produced by melasma, with low occurrence of side effects, which may be justified by the selective photothermolysis at subcellular level.
authors.affiliation: Dermatology Department, Jundiaí Medical School, Sao Paulo, Brazil.
authors.forename: Paulo Rowilson
authors.initials: PR
authors.lastname: Cunha
authors.affiliation: Pathotology Department, Jundiaí Medical School.
authors.forename: Clovis Antonio Lopes
authors.initials: CA
authors.lastname: Pinto
authors.affiliation: Dermatology Department, Jundiaí Medical School, Sao Paulo, Brazil.
authors.forename: Camila Bonati
authors.initials: CB
authors.lastname: Mattos
authors.affiliation: Dermatology Department, Jundiaí Medical School, Sao Paulo, Brazil.
authors.forename: Dayane Peverari
authors.initials: DP
authors.lastname: Cabrini
authors.affiliation: Jundiaí Medical School, Sao Paulo, Brazil.
authors.forename: Joana Lugli
authors.initials: JL
authors.lastname: Tolosa
mesh_terms: D000328:Adult; D005500:Follow-Up Studies; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000379:methods*; D008548:Melanosis / Q000473:pathology / Q000532:radiotherapy*; D016896:Treatment Outcome
keywords: ND:YAG laser; intense pulsed light; low-fluence laser; melanin pigment; melasma