title: Serum Metal Ions with a Titanium Modular Neck Total Hip Replacement System.
abstract: The goal of this study is to evaluate serum levels of chromium (Cr), cobalt (Co), and titanium (Ti) within the first two years following total hip arthroplasty using a Ti modular neck system. Twenty-five patients were randomized to a metal-on-metal (MoM) bearing with an all CoCr shell, and the remaining 25 received a metal-on-polyethylene (MoP) with a Ti shell. Serum levels demonstrated increases for Cr, Co, and Ti at 1 year (P < .001). MoM had similar Ti levels to MoP hips at 1 year (P=0.11) but lower at 2 years (P=0.03). Results suggest that the passive corrosion (i.e., chemical, pitting, and crevice corrosion) of exposed non-articular metal surfaces may be a greater source of ions than the neck-stem or head-neck interfaces.
authors.affiliation: The Ottawa Hospital - Civic Campus, Ottawa, Ontario, Canada.
authors.forename: Wade
authors.initials: W
authors.lastname: Gofton
authors.affiliation: The Ottawa Hospital - General Campus, Ottawa, ON, Canada.
authors.forename: Paul E
authors.initials: PE
authors.lastname: Beaule
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation* / Q000379:methods; D002857:Chromium / Q000097:blood; D003035:Cobalt / Q000097:blood; D003343:Corrosion; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D007477:Ions; D008297:Male; D008670:Metals / Q000097:blood*; D008875:Middle Aged; D020959:Polyethylene; D011446:Prospective Studies; D014025:Titanium / Q000097:blood / Q000737:chemistry*
chemical_list: D007477:Ions; D008670:Metals; D002857:Chromium; D003035:Cobalt; D020959:Polyethylene; D014025:Titanium
keywords: arthroplasty; hip; ions; modular; titanium