title: Blood Pressure and the Risk of Alzheimer's Disease: Is There a Link?
abstract: Alzheimer disease is one of the most common neurodegenerative disorder, and the incidence is increasing. Many epidemiologic studies have considered the association between blood pressure and Alzheimer disease, yet the relationship is still controversial. The objective of this study was to validate whether or not blood pressure is indeed associated with AD. We compared different prospective studies and ultimately found that it is also a controversial issue. Large prospective double-blinded and placebo-controlled studies conducted with the use of standardized outcome measures in different levels are necessary to assess the association of blood pressure and Alzheimer disease.
authors.affiliation: Department of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
authors.forename: Min
authors.initials: M
authors.lastname: Yuan
authors.affiliation: Department of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
authors.forename: Shen-Jian
authors.initials: SJ
authors.lastname: Chen
authors.affiliation: Department of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
authors.forename: Xue-Li
authors.initials: XL
authors.lastname: Li
authors.affiliation: Department of Neurology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China xulijun20050901@sina.com.
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Xu
mesh_terms: D000544:Alzheimer Disease / Q000209:etiology* / Q000503:physiopathology; D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000150:complications*; D051379:Mice; D012307:Risk Factors
keywords: Alzheimer’s disease; blood pressure; dementia; neurodegenerative disorder