title: A new gyrovirus in human feces.
abstract: A novel gyrovirus genome found in the feces of an adult with diarrhea is described. The genome shows the three expected main ORFs encoding a structural protein (VP1), nonstructural protein (VP2), and Apoptin protein (VP3), which shared identities of 41, 42, and 38 % with those of the most closely related gyrovirus proteins, respectively. Given the high divergence in its genome, this gyrovirus may be considered the prototype for a new viral species (GyV9) in the Gyrovirus genus. Because the closest relatives of this gyrovirus infect chicken, a possible dietary origin for the presence of this virus in human feces is discussed.
authors.affiliation: Blood Systems Research Institute, San Francisco, CA, 94118, USA.
authors.forename: Tung Gia
authors.initials: TG
authors.lastname: Phan
authors.forename: Antonio Charlys
authors.initials: AC
authors.lastname: da Costa
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
authors.forename: Pierre
authors.initials: P
authors.lastname: Pothier
authors.forename: Katia
authors.initials: K
authors.lastname: Ambert-Balay
authors.forename: Xutao
authors.initials: X
authors.lastname: Deng
authors.forename: Eric
authors.initials: E
authors.lastname: Delwart
mesh_terms: D000328:Adult; D018173:Circoviridae Infections / Q000821:virology*; D016000:Cluster Analysis; D004267:DNA Viruses / Q000235:genetics* / Q000302:isolation & purification; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D003967:Diarrhea / Q000821:virology*; D005243:Feces / Q000821:virology*; D016679:Genome, Viral; D046810:Gyrovirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
chemical_list: D004279:DNA, Viral