title: Pathophysiology after pancreaticoduodenectomy.
abstract: Pancreaticoduodenectomy (PD) will result in removal of important multiorgans in upper intestinal tract and subsequently secondary physiologic change. In the past, surgeons just focused on the safety of surgical procedure; however, PD is regarded as safe and widely applied to treatment of periampullary lesions. Practical issues after PD, such as, effect of duodenectomy, metabolic surgery-like effect, alignment effect of gastrointestinal continuity, and non-alcoholic fatty liver disease were summarized and discussed.
authors.affiliation: Chang Moo Kang, Jin Ho Lee, Department of Hepatobiliary and Pancreatic Surgery, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Chang Moo
authors.initials: CM
authors.lastname: Kang
authors.affiliation: Chang Moo Kang, Jin Ho Lee, Department of Hepatobiliary and Pancreatic Surgery, Yonsei University College of Medicine, Seoul 120-752, South Korea.
authors.forename: Jin Ho
authors.initials: JH
authors.lastname: Lee
mesh_terms: D004386:Duodenum / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery*; D004734:Energy Metabolism; D005767:Gastrointestinal Diseases / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology*; D005769:Gastrointestinal Motility; D006801:Humans; D065626:Non-alcoholic Fatty Liver Disease / Q000209:etiology / Q000503:physiopathology; D010179:Pancreas / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000009:adverse effects* / Q000401:mortality; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
keywords: Delayed gastric emptying; Exocrine insufficiency; Fatty liver; Metabolic surgery; Pancreaticoduodenectomy; Postoperative pancreatic fistula