title: Reply to J.N. Primrose et al and C.-H. Köhne.
authors.affiliation: Hôpital Ambroise Paré, Boulogne; and Assistance Publique Hôpitaux de Paris, Université de Versailles, Versailles, France.
authors.forename: Bernard M
authors.initials: BM
authors.lastname: Nordlinger
authors.affiliation: Aintree University Hospital; and Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
authors.forename: Graeme J
authors.initials: GJ
authors.lastname: Poston
authors.affiliation: The James Cancer Hospital and Solove Research Institute, The Ohio State University James Comprehensive Cancer Center, Columbus, OH richard.goldberg@osumc.edu.
authors.forename: Richard M
authors.initials: RM
authors.lastname: Goldberg
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000628:therapy*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D008297:Male; D010818:Practice Patterns, Physicians'; D018631:ras Proteins / Q000235:genetics*
chemical_list: D018631:ras Proteins