title: Ovary preservation in the treatment of childhood Meigs syndrome.
abstract: Meigs syndrome, the combination of benign ovarian tumor, ascites, and pleural effusion, is present in a small percentage of ovarian fibromas and is infrequently reported in children. When associated with elevated CA-125 suspicion is raised for malignancy, often prompting aggressive surgical intervention. We present a case of childhood Meigs syndrome and review the relevant literature with emphasis on ovary preservation. Out of nine identified pediatric cases, one involved ovary sparing treatment and none recurred or progressed to malignancy. Our report highlights the importance of presurgical identification of Meigs syndrome in order to curtail salpingo-oophorectomy when feasible.
authors.affiliation: Albert Einstein College of Medicine, Bronx, New York.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Fremed
authors.affiliation: Department of Radiology, Division of Pediatric Radiology, Montefiore Medical Center, Bronx, New York.
authors.forename: Terry L
authors.initials: TL
authors.lastname: Levin
authors.affiliation: Department of Pathology, Montefiore Medical Center, Bronx, New York.
authors.forename: Katherine Y
authors.initials: KY
authors.lastname: Sun
authors.affiliation: Departments of Pediatrics and Genetics, Albert Einstein College of Medicine, Bronx, New York.|Division of Pediatric Hematology/Oncology, Children's Hospital at Montefiore, Bronx, New York.
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Weiser
mesh_terms: D000293:Adolescent; D018394:CA-125 Antigen / Q000097:blood; D005260:Female; D006801:Humans; D008539:Meigs Syndrome / Q000097:blood / Q000601:surgery*; D008565:Membrane Proteins / Q000097:blood; D059351:Organ Sparing Treatments / Q000379:methods*; D010053:Ovary / Q000601:surgery*
chemical_list: D018394:CA-125 Antigen; C451759:MUC16 protein, human; D008565:Membrane Proteins
keywords: childhood Meigs syndrome; ovary preservation