title: Fully automated simultaneous umbilical arteriovenous exchange transfusion in term and late preterm infants with neonatal hyperbilirubinemia.
abstract: OBJECTIVE
  The purpose of this study was to compare the efficacy and safety of two different catheterization techniques of exchange transfusion (ET) used in the therapy of newborn jaundice: fully automated two-way ET technique and the classical one-way ET.
  
  
  METHODS
  The study included babies at gestational age of >34 weeks. In total, 107 ETs were performed on 86 babies. Totally, the umbilical vein (UV) group included 54 babies having undergone 69 ETs and the UV/UA group included 32 babies having undergone 38 ETs.
  
  
  RESULTS
  The declines in bilirubin levels right after ET (p = 0.018) and 8 h after ET (p = 0.014) were higher in the fully automated UV/UA technique than in the classical UV technique. Furthermore, the duration of intensive phototherapy following ET was shorter in the UV/UA method than in the UV method (p = 0.003). There was no difference between the two methods in terms of ET-associated complications (p = 0.927).
  
  
  CONCLUSIONS
  In neonatal hyperbilirubinemia, ET with fully automated UV/UA technique is more efficient than the classical ET technique, causing no additional side-effects. It is also more physiological than the classical technique, since it minimizes the fluctuations in the blood volume and intravascular pressure during ET.
authors.affiliation: a Faculty of Medicine , Selcuk University , Neonatology, Konya , Turkey.
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Altunhan
authors.affiliation: a Faculty of Medicine , Selcuk University , Neonatology, Konya , Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Annagür
authors.affiliation: a Faculty of Medicine , Selcuk University , Neonatology, Konya , Turkey.
authors.forename: Nuriye
authors.initials: N
authors.lastname: Tarakçi
authors.affiliation: a Faculty of Medicine , Selcuk University , Neonatology, Konya , Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Konak
authors.affiliation: a Faculty of Medicine , Selcuk University , Neonatology, Konya , Turkey.
authors.forename: Sabahattin
authors.initials: S
authors.lastname: Ertuğrul
authors.affiliation: a Faculty of Medicine , Selcuk University , Neonatology, Konya , Turkey.
authors.forename: Rahmi
authors.initials: R
authors.lastname: Örs
mesh_terms: D005078:Exchange Transfusion, Whole Blood / Q000379:methods*; D005260:Female; D006801:Humans; D051556:Hyperbilirubinemia, Neonatal / Q000628:therapy*; D007231:Infant, Newborn; D007234:Infant, Premature; D007567:Jaundice, Neonatal / Q000628:therapy*; D008297:Male; D010789:Phototherapy / Q000706:statistics & numerical data; D012189:Retrospective Studies; D014469:Umbilical Arteries; D014471:Umbilical Veins
keywords: Automated exchange transfusion; exchange transfusion; neonatal hyperbilirubinemia; umbilical artery; umbilical vein