title: [Identification of biological processes on the composition of the urine proteome in cosmonauts on the first day after long space flights].
abstract: There are several difficulties that impede medical support of space missions. We can assume that the long-term space missions will be accompanied by functional changes in the organism. These changes will be a natural reaction to the factors of space flight. Complex action of factors can lead to the development of both non-specific changes (general adaptation syndrome), and specific changes. We analyzed the physiological changes after long space flights and carried out the correlation of these changes with previously identified proteins in the urine. It is possible to determine the mechanisms of adaptation of the human organism to the conditions of life on Earth after a long stay in Earth orbit.
authors.forename: L H
authors.initials: LH
authors.lastname: Pastushkova
authors.forename: A S
authors.initials: AS
authors.lastname: Kononihin
authors.forename: E S
authors.initials: ES
authors.lastname: Tijs
authors.forename: O A
authors.initials: OA
authors.lastname: Obraztsova
authors.forename: I V
authors.initials: IV
authors.lastname: Dobrokhotov
authors.forename: V A
authors.initials: VA
authors.lastname: Ivanisenko
authors.forename: E N
authors.initials: EN
authors.lastname: Nikolaev
authors.forename: I M
authors.initials: IM
authors.lastname: Larina
mesh_terms: D000222:Adaptation, Physiological; D000975:Antioxidants / Q000378:metabolism; D018480:Astronauts; D002320:Cardiovascular Physiological Phenomena; D006112:Gravitation; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology; D009142:Musculoskeletal Physiological Phenomena; D020543:Proteome / Q000378:metabolism*; D040901:Proteomics; D013026:Space Flight; D014556:Urine / Q000737:chemistry*; D014882:Water-Electrolyte Balance
chemical_list: D000975:Antioxidants; D020543:Proteome