title: Incision and Curettage Versus Steroid Injection for the Treatment of Chalazia: A Meta-Analysis.
abstract: OBJECTIVE
  To compare the efficacy of the chalazia treatment modalities of incision and curettage (I&C) and intralesional steroid injections (SI).
  
  
  METHODS
  Full publications of randomized controlled trials that compared I&C with SI were identified. Aggregated success rate, weighted summary proportions, and weighted pooled relative risk for success were calculated for each method.
  
  
  RESULTS
  Data were extracted from 8 publications that met these criteria, between 1984 and 2013. There were 288 patients treated by SI with aggregate success rate of 60.4% with 1 injection and 72.5% with 1 or 2 injections. The range of the success rate was 8.7 to 86.7% for 1 injection. The success rate for the second SI was 19.0%, with a range of 0% to 53.8%. There were 264 patients treated by I&C with a larger aggregate success rate of 78.0% with 1 procedure and 86.7% with 1 or 2 procedures (p < 0.05 for both comparisons). The range of the success rates was 60.0% to 92.0% for 1 I&C. The success rate for the second I&C was 90.65%, with a range of 83.3% to 100%. Compared with I&C, the overall relative risk for SI with 1 procedure was 0.77 (p = 0.05), while the overall relative risk for 1 or 2 procedures was 0.89 (p = 0.002).
  
  
  CONCLUSIONS
  This analysis shows that I&C is more effective than SI with 1 procedure. This benefit is reduced when comparing 1 or 2 attempts of I&C and SI. Studies failed to show a difference in the incidence of complications with either procedure.
authors.affiliation: *Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel; and †Department of Ophthalmology, The Edith Wolfson Medical Center, Holon, Israel.
authors.forename: Alicia R P
authors.initials: AR
authors.lastname: Aycinena
authors.forename: Asaf
authors.initials: A
authors.lastname: Achiron
authors.forename: Michael
authors.initials: M
authors.lastname: Paul
authors.forename: Zvia
authors.initials: Z
authors.lastname: Burgansky-Eliash
mesh_terms: D017043:Chalazion / Q000628:therapy*; D003475:Curettage / Q000379:methods*; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D015552:Injections, Intralesional; D016032:Randomized Controlled Trials as Topic; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide