title: Size doesn't matter; in the stroma, little things make all the difference.
abstract: In recent years there has been an increase in the number of studies into the role of stromal cells and microRNAs (miRNAs) in kidney development. Nakagawa et al. combine the two in a study of a stromal cell-specific knockout of Dicer1. The work identifies many important roles for miRNAs in these cells and kidney development in general, partially through their modification of the β-catenin signaling cascade.
authors.affiliation: The Roslin Institute, University of Edinburgh, Midlothian, UK.
authors.forename: Derya D
authors.initials: DD
authors.lastname: Ozdemir
authors.affiliation: The Roslin Institute, University of Edinburgh, Midlothian, UK.
authors.forename: Peter
authors.initials: P
authors.lastname: Hohenstein
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000235:genetics*; D053487:DEAD-box RNA Helicases / Q000502:physiology*; D005260:Female; D018919:Neovascularization, Physiologic / Q000235:genetics*; D009399:Nephrons / Q000196:embryology*; D043244:Ribonuclease III / Q000502:physiology*
chemical_list: D043244:Ribonuclease III; D053487:DEAD-box RNA Helicases