title: Colorimetric Detection of Creatinine Based on Plasmonic Nanoparticles via Synergistic Coordination Chemistry.
abstract: A simple and portable colorimetric assay for creatinine detection is fabricated based on the synergistic coordination of creatinine and uric acid with Hg(2+) on the surface of gold nanoparticles, which exhibits good selectivity and sensitivity. Point-of-care clinical creatinine monitoring can be supported for monitoring renal function and diagnosing corresponding renal diseases at home.
authors.affiliation: State Key Laboratory of Fine Chemicals, Dalian University of Technology, 2 Linggong Road, Dalian, 116024, China.
authors.forename: Jianjun
authors.initials: J
authors.lastname: Du
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore.
authors.forename: Bowen
authors.initials: B
authors.lastname: Zhu
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore.
authors.forename: Wan Ru
authors.initials: WR
authors.lastname: Leow
authors.affiliation: Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, 637371, Singapore.
authors.forename: Shi
authors.initials: S
authors.lastname: Chen
authors.affiliation: Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, 637371, Singapore.
authors.forename: Tze Chien
authors.initials: TC
authors.lastname: Sum
authors.affiliation: State Key Laboratory of Fine Chemicals, Dalian University of Technology, 2 Linggong Road, Dalian, 116024, China.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Peng
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Chen
mesh_terms: D015374:Biosensing Techniques / Q000379:methods; D002623:Chemistry Techniques, Analytical / Q000379:methods*; D003124:Colorimetry / Q000379:methods; D056831:Coordination Complexes / Q000737:chemistry; D003404:Creatinine / Q000032:analysis* / Q000652:urine; D006046:Gold / Q000737:chemistry*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry; D020349:Surface Plasmon Resonance; D016482:Urinalysis / Q000379:methods
chemical_list: D056831:Coordination Complexes; D012710:Serum Albumin, Bovine; D006046:Gold; D003404:Creatinine
keywords: colorimetric assay; creatinine detection; plasmonic nanoparticle; synergistic coordination