title: Main characteristics of metabolically obese normal weight and metabolically healthy obese phenotypes.
abstract: In this review, the influence of fat depots on insulin resistance and the main characteristics of metabolically obese normal-weight and metabolically healthy obese phenotypes are discussed. Medline/PubMed and Science Direct were searched for articles related to the terms metabolically healthy obesity, metabolically obese normal weight, adipose tissue, and insulin resistance. Normal weight and obesity might be heterogeneous in regard to their effects. Fat distribution and lower insulin sensitivity are the main factors defining phenotypes within the same body mass index. Although these terms are interesting, controversies about them remain. Future studies exploring these phenotypes will help elucidate the roles of adiposity and/or insulin resistance in the development of metabolic alterations.
authors.affiliation: TFS Teixeira, RDM Alves, APB Moreira, and MdCG Peluzio are with the Nutrition and Health Department, Federal University of Viçosa, Viçosa, MG, Brazil. tatiana.salles@ufv.br tatifichee@hotmail.com.
authors.forename: Tatiana F S
authors.initials: TF
authors.lastname: Teixeira
authors.affiliation: TFS Teixeira, RDM Alves, APB Moreira, and MdCG Peluzio are with the Nutrition and Health Department, Federal University of Viçosa, Viçosa, MG, Brazil.
authors.forename: Raquel D M
authors.initials: RD
authors.lastname: Alves
authors.affiliation: TFS Teixeira, RDM Alves, APB Moreira, and MdCG Peluzio are with the Nutrition and Health Department, Federal University of Viçosa, Viçosa, MG, Brazil.
authors.forename: Ana Paula B
authors.initials: AP
authors.lastname: Moreira
authors.affiliation: TFS Teixeira, RDM Alves, APB Moreira, and MdCG Peluzio are with the Nutrition and Health Department, Federal University of Viçosa, Viçosa, MG, Brazil.
authors.forename: Maria do Carmo G
authors.initials: Mdo C
authors.lastname: Peluzio
mesh_terms: D050154:Adiposity / Q000502:physiology*; D000328:Adult; D015992:Body Mass Index; D001835:Body Weight / Q000502:physiology*; D005260:Female; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D008297:Male; D009765:Obesity / Q000503:physiopathology*; D013008:Somatotypes / Q000502:physiology*
keywords: adiposity; insulin resistance; obesity