title: [Pathophysiological changes in mitochondria of mammalian exposed to hypoxia at high altitude].
abstract: As human beings ascend to high altitude, a number of reactions may occur against hypoxic injuries. These hypoxic responses are related to intake, transportation and utility of the oxygen. As a crucial subcellular organelle of oxygen utility, mitochondrion is a central link of high altitude acclimatization, adaptation and mountain sicknesses. In this review, we discussed the recent advances in researches on hypoxic mitochondrial responses at high altitude.
authors.forename: Wen-xiang
authors.initials: WX
authors.lastname: Gao
authors.forename: Gang
authors.initials: G
authors.lastname: Wu
authors.forename: Yu-qi
authors.initials: YQ
authors.lastname: Gao
mesh_terms: D000222:Adaptation, Physiological; D000531:Altitude; D000532:Altitude Sickness; D000818:Animals; D006801:Humans; D000860:Hypoxia; D008928:Mitochondria / Q000473:pathology*; D010100:Oxygen / Q000502:physiology
chemical_list: D010100:Oxygen