title: Fasciculations masquerading as minipolymyoclonus in bulbospinal muscular atrophy.
abstract: Minipolymyoclonus has been described in both anterior horn cell disorders and central nervous system degenerative conditions. While its etiology remains unclear and speculative, a central generator has been previously proposed. We describe a case of bulbospinal muscular atrophy (Kennedy's disease), where minipolymyoclonus-like movements corresponded to fasciculations in neurophysiological studies. Our novel finding suggests that the etiologies of minipolymyoclonus in central and peripheral nervous system disorders are distinct, despite outward clinical similarity. The term "minipolyfasciculations" may be more reflective of the underlying process causing minipolymyoclonus-like movements in lower motor neuron disorders.
authors.affiliation: Department of Neurology, JFK Neuroscience Institute, Seton Hall University, Edison, New Jersey, United States.
authors.forename: Sushanth
authors.initials: S
authors.lastname: Bhat
authors.affiliation: Department of Neurology, JFK Neuroscience Institute, Seton Hall University, Edison, New Jersey, United States.
authors.forename: Wei
authors.initials: W
authors.lastname: Ma
authors.affiliation: Department of Neurology, JFK Neuroscience Institute, Seton Hall University, Edison, New Jersey, United States.
authors.forename: Elena
authors.initials: E
authors.lastname: Kozochonok
authors.affiliation: Department of Neurology, JFK Neuroscience Institute, Seton Hall University, Edison, New Jersey, United States.
authors.forename: Sudhansu
authors.initials: S
authors.lastname: Chokroverty
keywords: Bulbospinal muscular atrophy; EMG-EEG back averaging; Kennedy's disease; minipolymyoclonus; polyminimyoclonus