title: [Complications and effectiveness of treatment of patients with locally advanced prostate cancer after combined radiotherapy and radical prostatectomy with postoperative radiotherapy].
abstract: Treatment for prostate cancer remains a significant social problem due to the continuing trend of growth of morbidity and mortality in Russia from this disease. In recent years a real alternative to surgical treatment is radiotherapy. In treatment of locally advanced stages of prostate cancer radiotherapy plays a dominant role. At our institution from 2005 till 2011, 105 patients with locally advanced prostate cancer underwent complex and combined treatment comprising in the first group the concomitant radiotherapy with Ir-192 and the control group--radical prostatectomy followed by adjuvant remote radiotherapy. In patients treated with concomitant radiotherapy compared to the control group there were occurred fewer number of genitourinary complications according to the RTOG scale (5,8% vs. 32,7%). In patients who had undergone radical prostatectomy followed by adjuvant radiotherapy urinary incontinence was met significantly often.
authors.forename: V A
authors.initials: VA
authors.lastname: Solodky
authors.forename: A Yu
authors.initials: AY
authors.lastname: Pavlov
authors.forename: G A
authors.initials: GA
authors.lastname: Panshin
authors.forename: A D
authors.initials: AD
authors.lastname: Tsybulsky
authors.forename: S V
authors.initials: SV
authors.lastname: Garmash
authors.forename: T K
authors.initials: TK
authors.lastname: Isaev
authors.forename: I B
authors.initials: IB
authors.lastname: Kravtsov
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D007172:Erectile Dysfunction / Q000209:etiology; D006801:Humans; D015994:Incidence; D007432:Intraoperative Period; D007496:Iridium Radioisotopes / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011184:Postoperative Period; D011468:Prostatectomy / Q000379:methods*; D011471:Prostatic Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D012426:Russia; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000209:etiology
chemical_list: D007496:Iridium Radioisotopes