title: Bilateral Choroid Plexus Metastasis from Papillary Thyroid Carcinoma: Case Report and Review of the Literature.
abstract: BACKGROUND
  Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. It has an indolent clinical course and favorable prognosis. Brain metastasis is uncommon and complicates about 0.1%-5% of PTCs. Metastasis to the choroid plexus of the lateral ventricles has been reported in 7 cases of thyroid malignancies, all of which were unilateral.
  
  
  METHODS
  We report a case of a 52-year-old woman with a history of PTC who presented with severe headache, nausea and vomiting, right hemiparesis, and speech disturbance. Imaging studies depicted lesions in both lateral ventricles.
  
  
  RESULTS
  The patient underwent microsurgical tumor resection. Histopathologic examination revealed choroid plexus metastasis from PTC.
  
  
  CONCLUSIONS
  Metastases to the choroid plexus from extracranial tumors are very rare, with only a few cases reported thus far. A demographic analysis of these cases suggests there may be a tropism of some extracranial carcinomas, such as renal cell carcinoma, for choroid plexus, especially in the lateral ventricles. We report the eighth case of choroid plexus metastasis, but it is the first bilateral one arising from thyroid cancer.
authors.affiliation: Department of Neurosurgery, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Guive
authors.initials: G
authors.lastname: Sharifi
authors.affiliation: Department of Neurosurgery, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: mehrdaada@yahoo.com.
authors.forename: Mehrdad Hosseinzadeh
authors.initials: MH
authors.lastname: Bakhtevari
authors.affiliation: Department of Neurosurgery, Firuzgar Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Alghasi
authors.affiliation: Department of Neurosurgery, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Masood Asghsri
authors.initials: MA
authors.lastname: Nosari
authors.affiliation: Department of Neurosurgery, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Ramin
authors.initials: R
authors.lastname: Rahmanzade
authors.affiliation: Department of Neurosurgery, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Omidvar
authors.initials: O
authors.lastname: Rezaei
mesh_terms: D002277:Carcinoma / Q000473:pathology*; D002291:Carcinoma, Papillary / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D002551:Cerebral Ventricle Neoplasms / Q000473:pathology / Q000601:surgery; D016545:Choroid Plexus Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D020547:Lateral Ventricles / Q000473:pathology / Q000601:surgery; D018810:Magnetic Resonance Angiography; D008866:Microsurgery; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology; D019635:Neurosurgical Procedures; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000473:pathology*
keywords: Choroid plexus metastasis; Intraventricular tumors; Papillary thyroid carcinoma