title: Microwave Ablation Compared to Radiofrequency Ablation for Hepatic Lesions: A Meta-Analysis.
abstract: To evaluate the efficacy and safety of microwave (MW) ablation compared with radiofrequency (RF) ablation for hepatic lesions by using meta-analytic techniques. Overall, 16 studies involving 2,062 patients were included. MW ablation was found to have significantly better 6-year overall survival than RF ablation (odds ratio, 1.64, 95% confidence interval, 1.15-2.35), but this was based on a few articles (n = 3 of 16). MW ablation and RF ablation had similar 1-5-year overall survival, disease-free survival, local recurrence rate, and adverse events. Based on similar safety and efficacy outcomes, either MW ablation or RF ablation may be used for effective local hepatic therapy.
authors.affiliation: Discipline of Surgery, The Whiteley-Martin Research Centre, University of Sydney, Nepean Hospital, Level 3, Clinical Building, P.O. Box 63, Penrith, NSW 2751, Australia.
authors.forename: Ya Ruth
authors.initials: YR
authors.lastname: Huo
authors.affiliation: Discipline of Surgery, The Whiteley-Martin Research Centre, University of Sydney, Nepean Hospital, Level 3, Clinical Building, P.O. Box 63, Penrith, NSW 2751, Australia.. Electronic address: guy.eslick@sydney.edu.au.
authors.forename: Guy D
authors.initials: GD
authors.lastname: Eslick
mesh_terms: D000368:Aged; D017115:Catheter Ablation / Q000401:mortality*; D005260:Female; D006801:Humans; D015994:Incidence; D008113:Liver Neoplasms / Q000401:mortality* / Q000601:surgery*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality* / Q000517:prevention & control*; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome