title: Cyclodextrin nanoassemblies: a promising tool for drug delivery.
abstract: Among the biodegradable and nontoxic compounds that can form nanoparticles for drug delivery, amphiphilic cyclodextrins are very promising. Apart from ionic cyclodextrins, which have been extensively studied and reviewed because of their application in gene delivery, our purpose is to provide a clear description of the supramolecular assemblies of nonionic amphiphilic cyclodextrins, which can form nanoassemblies for controlled drug release. Moreover, we focus on the relationship between their structure and physicochemical characteristics, which is crucial for self assembly and drug delivery. We also highlight the importance of the nanoparticle technology preparation for the stability and application of this nanodevice.
authors.affiliation: Laboratoire de Glycochimie des Antimicrobiens et des Agroressources (LG2A), FRE 3517 CNRS Université de Picardie Jules Verne, ICP FR3085 CNRS, 80039 Amiens, France. Electronic address: veronique.bonnet@u-picardie.fr.
authors.forename: Véronique
authors.initials: V
authors.lastname: Bonnet
authors.affiliation: Laboratoire de Glycochimie des Antimicrobiens et des Agroressources (LG2A), FRE 3517 CNRS Université de Picardie Jules Verne, ICP FR3085 CNRS, 80039 Amiens, France; Génie Enzymatique et Cellulaire, FRE3580 CNRS, Université de Picardie Jules Verne, 80039 Amiens, France.
authors.forename: Cédric
authors.initials: C
authors.lastname: Gervaise
authors.affiliation: Laboratoire de Glycochimie des Antimicrobiens et des Agroressources (LG2A), FRE 3517 CNRS Université de Picardie Jules Verne, ICP FR3085 CNRS, 80039 Amiens, France.
authors.forename: Florence
authors.initials: F
authors.lastname: Djedaïni-Pilard
authors.affiliation: Génie Enzymatique et Cellulaire, FRE3580 CNRS, Université de Picardie Jules Verne, 80039 Amiens, France.
authors.forename: Aurélien
authors.initials: A
authors.lastname: Furlan
authors.affiliation: Génie Enzymatique et Cellulaire, FRE3580 CNRS, Université de Picardie Jules Verne, 80039 Amiens, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Sarazin
mesh_terms: D003505:Cyclodextrins / Q000737:chemistry*; D003692:Delayed-Action Preparations; D004337:Drug Carriers / Q000737:chemistry; D016503:Drug Delivery Systems; D004355:Drug Stability; D018014:Gene Transfer Techniques; D006801:Humans; D053758:Nanoparticles; D036103:Nanotechnology
chemical_list: D003505:Cyclodextrins; D003692:Delayed-Action Preparations; D004337:Drug Carriers