title: Assessing anxiety and depression with respect to the quality of life in cancer inpatients receiving palliative care.
abstract: OBJECTIVE
  The study aimed at assessing the presence of anxiety and depression in cancer inpatients receiving palliative care at an oncology department using the Hospital Anxiety and Depression Scale (HADS) and determining whether anxiety and depression contribute to a lower quality of life controlled for pain and illness severity.
  
  
  METHODS
  This cross-sectional study comprised 225 advanced cancer inpatients (a mean age of 65.1 years). Data were collected with the HADS, EORTC QLQ-C30 and Karnofsky Performance Status scale.
  
  
  RESULTS
  Anxiety (HADS-a ≥8) was found in 33.9% and depression (HADS-d ≥8) in 47.6% of patients. Higher anxiety scores were observed in patients living with a partner (p = 0.042) and non-religious patients (p = 0.045). Correlations were found between anxiety, depression and all quality of life dimensions (r = 0.31-0.63). Multiple regression analysis showed that anxiety and depression contribute to lower physical and emotional functioning. Patients with anxiety (HADS-a ≥8) and depression (HADS-d ≥8) reported a lower total quality of life (p < 0.01).
  
  
  CONCLUSIONS
  Management of anxiety and depression in cancer patients receiving palliative care may contribute to improvement in certain quality of life dimensions.
authors.affiliation: Department of Nursing and Midwifery, Faculty of Medicine, University of Ostrava, Syllabova 19, Ostrava 700 30, Czech Republic. Electronic address: radka.buzgova@osu.cz.
authors.forename: Radka
authors.initials: R
authors.lastname: Bužgová
authors.affiliation: Department of Nursing and Midwifery, Faculty of Medicine, University of Ostrava, Syllabova 19, Ostrava 700 30, Czech Republic. Electronic address: darja.jarosova@osu.cz.
authors.forename: Darja
authors.initials: D
authors.lastname: Jarošová
authors.affiliation: Clinic of Oncology, University Hospital Ostrava, Czech Republic; Department of Nursing and Midwifery, Faculty of Medicine, University of Ostrava, Syllabova 19, Ostrava 700 30, Czech Republic. Electronic address: erika.hajnova@fno.cz.
authors.forename: Erika
authors.initials: E
authors.lastname: Hajnová
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001008:Anxiety Disorders / Q000453:epidemiology* / Q000503:physiopathology / Q000523:psychology; D003430:Cross-Sectional Studies; D018153:Czech Republic; D003866:Depressive Disorder / Q000453:epidemiology* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007297:Inpatients / Q000523:psychology / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000175:diagnosis / Q000523:psychology* / Q000628:therapy*; D010166:Palliative Care / Q000379:methods / Q000523:psychology*; D015995:Prevalence; D011788:Quality of Life; D012044:Regression Analysis; D018570:Risk Assessment
keywords: Advanced cancer; Anxiety; Depression; Palliative care; Quality of life