title: Palladium-catalyzed ortho-acyloxylation of N-nitrosoanilines via direct sp(2) C-H bond activation.
abstract: The palladium-catalyzed N-nitroso-directed ortho-acyloxylation of N-nitrosoanilines has been demonstrated via sp(2) C-H activation with a stoichiometric amount of PhI(OAc)2 as the oxidant and Ac2O/AcOH (1 : 1) or C2H5CO2H as the reaction medium. This protocol can be applied to various N-nitrosoanilines with both electron-donating and electron-withdrawing groups. In addition, the products can be further transformed to 2-(methylamino)phenols expediently by a simple reduction method.
authors.affiliation: Hefei National Laboratory for Physical Sciences at Microscale, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials), and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China. gwang@ustc.edu.cn.
authors.forename: Dan-Dan
authors.initials: DD
authors.lastname: Li
authors.forename: Yi-Xuan
authors.initials: YX
authors.lastname: Cao
authors.forename: Guan-Wu
authors.initials: GW
authors.lastname: Wang