title: A catalytic asymmetric carbonyl-ene reaction of β,γ-unsaturated α-ketoesters with 5-methyleneoxazolines.
abstract: A catalytic asymmetric carbonyl-ene reaction of β,γ-unsaturated α-ketoesters with 5-methyleneoxazolines was accomplished. The process was based on the utilization of a chiral N,N'-dioxide/Mg(II) catalyst, providing the desired products with excellent outcomes (up to 99% yield, >99% ee) under mild reaction conditions. Based on the experimental investigations and previous reports, a possible transition state was proposed.
authors.affiliation: Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, P. R. China. xmfeng@scu.edu.cn.
authors.forename: Weiwei
authors.initials: W
authors.lastname: Luo
authors.forename: Jiannan
authors.initials: J
authors.lastname: Zhao
authors.forename: Jie
authors.initials: J
authors.lastname: Ji
authors.forename: Lili
authors.initials: L
authors.lastname: Lin
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Liu
authors.forename: Hongjiang
authors.initials: H
authors.lastname: Mei
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Feng