title: Health-related quality of life after stroke: reliability and validity of the Duke Health Profile for use in Vietnam.
abstract: BACKGROUND
  Health-related quality of life (HRQoL) is commonly used to assess outcomes after stroke. The Duke Health Profile (DHP) has been translated and culturally adapted for use in Vietnam, but its reliability and validity for use with stroke patients in Vietnam or elsewhere have not been assessed.
  
  
  METHODS
  First-ever stroke patients (n = 108) who were admitted to 115 People's Hospital between February and September 2012 and survived for 3 months after stroke had HRQoL assessed using the DHP and a comparison instrument (EQ-5D). Caregivers of 94 patients completed these questionnaires as a proxy. After 1 week, these questionnaires were re-administered to patients and proxies.
  
  
  RESULTS
  The mean differences between test and retest assessments of HRQoL by patients were small and not clinically meaningful and were not consistently associated with sex, age, type of stroke or severity of impairment or disability. Direct assessments by the patient were on average greater than those obtained from the proxy. The ICCs ranged from 0.60 to 0.86 (patient test-retest) and from 0.55 to 0.98 (patient-proxy agreement). The ICCs were greatest for physical functioning components (patient test-retest 0.63-0.86, patient-proxy 0.69-0.98). The correlations between the DHP dimensions and EQ-5D were generally stronger when they measured similar constructs (r = 0.53-0.66) and were lower for less related constructs (r = 0.11-0.43).
  
  
  CONCLUSIONS
  The DHP has moderate reliability and validity for use with stroke patients in Vietnam even when information is obtained from proxy respondents.
authors.affiliation: Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool Street, Hobart, TAS, 7000, Australia.|Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
authors.forename: Pham L
authors.initials: PL
authors.lastname: Tran
authors.affiliation: Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool Street, Hobart, TAS, 7000, Australia. Leigh.Blizzard@utas.edu.au.
authors.forename: C
authors.initials: C
authors.lastname: Leigh Blizzard
authors.affiliation: Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool Street, Hobart, TAS, 7000, Australia.|Stroke and Ageing Research Centre, School of Clinical Sciences, Monash University, Melbourne, Australia.
authors.forename: Velandai
authors.initials: V
authors.lastname: Srikanth
authors.affiliation: Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam.
authors.forename: Vo T X
authors.initials: VT
authors.lastname: Hanh
authors.affiliation: Stroke Unit, Cerebrovascular Disease Department, 115 People's Hospital, Ho Chi Minh City, Vietnam.
authors.forename: Nguyen T K
authors.initials: NT
authors.lastname: Lien
authors.affiliation: Stroke Unit, Cerebrovascular Disease Department, 115 People's Hospital, Ho Chi Minh City, Vietnam.
authors.forename: Nguyen H
authors.initials: NH
authors.lastname: Thang
authors.affiliation: Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool Street, Hobart, TAS, 7000, Australia.
authors.forename: Seana L
authors.initials: SL
authors.lastname: Gall
mesh_terms: D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D000071939:Stroke Rehabilitation; D014744:Vietnam
keywords: Duke Health Profile; Health-related quality of life; Reliability; Stroke; Validity