title: Useful Strategy of Pulmonary Microvascular Cytology in the Early Diagnosis of Intravascular Large B-cell Lymphoma in a Patient with Hypoxemia: A Case Report and Literature Review.
abstract: Intravascular large B-cell lymphoma (IVLBCL) is a rare extranodal lymphoma characterized by the presence of tumor cells within blood vessels, and it is considered to be a subtype of diffuse large B-cell lymphoma. We report a case of IVLBCL presenting as progressive hypoxemia. In this case, a definitive diagnosis could not be achieved by repeated transbronchial lung biopsy, a bone marrow biopsy, and a random skin biopsy, and the ultimate diagnosis was made on the basis of a pulmonary microvascular cytology (PMC) examination. Therefore, PMC is considered to be a useful strategy for the diagnosis of IVLBCL, particularly in this critically ill patient suffering from hypoxemia.
authors.affiliation: Division of Respiratory Medicine, Department of Internal Medicine, Jikei University School of Medicine, Kashiwa Hospital, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Yamakawa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yoshida
authors.forename: Masami
authors.initials: M
authors.lastname: Yabe
authors.forename: Emiri
authors.initials: E
authors.lastname: Baba
authors.forename: Takeo
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Masamichi
authors.initials: M
authors.lastname: Takagi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Katagi
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Kuwano
mesh_terms: D000369:Aged, 80 and over; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D006801:Humans; D000860:Hypoxia / Q000175:diagnosis; D008168:Lung / Q000098:blood supply; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D008297:Male; D055806:Microvessels / Q000473:pathology*; D012867:Skin / Q000473:pathology