title: Hypertension and cochlear hearing loss.
abstract: This paper presents a review of experimental and clinical research on the contribution of hypertension to cochlear hearing loss. Hypertension is one of the crucial risk factors underlying pathophysiological processes taking place in the cochlea. Several mechanisms explaining these processes have been described, mainly in animal models, such as the disturbance of the inner ear potassium recycling process due to the detrimental action of natriuretic hormone, and the decrease in the cochlear oxygen partial pressure. Current evidence linking hypertension to sensorineural high-frequency cochlear hearing loss in humans may be confounded by other concomitant diseases or risk factors such as age, coronary artery disease, diabetes, obesity, hyperlipidemia, smoking and noise exposure. Therefore, further research in this field is clearly needed.
authors.affiliation: Department of Otolaryngology, Medical University of Gdańsk , Gdańsk , Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Przewoźny
authors.forename: Anna
authors.initials: A
authors.lastname: Gójska-Grymajło
authors.forename: Mariusz
authors.initials: M
authors.lastname: Kwarciany
authors.forename: Dariusz
authors.initials: D
authors.lastname: Gąsecki
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Narkiewicz
mesh_terms: D002908:Chronic Disease; D006319:Hearing Loss, Sensorineural / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology
keywords: Cochlear hearing loss; hypertension; inner ear diseases