title: Emphysema and COPD in a young woman.
abstract: A 28-year old woman presented with a progressive cough and breathlessness. She had a family history of early onset COPD. Spirometry demonstrated airflow obstruction with no reversibility. An HRCT showed extensive centrolobular emphysema with an upper lobe predominance. Blood tests including an Alpha - 1 Antitrypsin level were normal.
authors.affiliation: Department of Respiratory Medicine, South Tyneside District Hospital, Harton Lane, South Shields, Tyne and Wear NE34 OPL, UK.
authors.forename: Kevin
authors.initials: K
authors.lastname: Conroy
authors.affiliation: Department of Respiratory Medicine, South Tyneside District Hospital, Harton Lane, South Shields, Tyne and Wear NE34 OPL, UK.
authors.forename: Graham
authors.initials: G
authors.lastname: Miller
authors.affiliation: Department of Respiratory Medicine, South Tyneside District Hospital, Harton Lane, South Shields, Tyne and Wear NE34 OPL, UK.
authors.forename: Mark
authors.initials: M
authors.lastname: Shipley
keywords: Alpha-1-antitrypsin; Emphysema; Young