title: The neurocognitive profile of the cerebellum in multiple sclerosis.
abstract: In recent years, a high number of studies have demonstrated that neuropsychological functions are altered in multiple sclerosis (MS) patients with cerebellar lesions, mainly including attention, working memory and verbal fluency. Since the present literature is often elusive on this topic, we aim to provide a comprehensive report about the real impact of cerebellar damages (evaluated as volume, lesions or connectivity measures) on cognitive functions. In particular in this review, we report and discuss recent works from 2009 to 2015, which have demonstrated the key role of the cerebellum in cognitive impairment of MS patients.
authors.affiliation: Istituto di Bioimmagini e Fisiologia Molecolare (IBFM), National Research Council (CNR), Catanzaro 88100, Italy. sarica@unicz.it.
authors.forename: Alessia
authors.initials: A
authors.lastname: Sarica
authors.affiliation: Istituto di Bioimmagini e Fisiologia Molecolare (IBFM), National Research Council (CNR), Catanzaro 88100, Italy. a.cerasa@unicz.it.
authors.forename: Antonio
authors.initials: A
authors.lastname: Cerasa
authors.affiliation: Institute of Neurology, University Magna Graecia, Germaneto, Catanzaro 88100, Italy. quattrone@unicz.it.
authors.forename: Aldo
authors.initials: A
authors.lastname: Quattrone
mesh_terms: D002531:Cerebellum / Q000473:pathology*; D003072:Cognition Disorders / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D009483:Neuropsychological Tests
keywords: cerebellum; cognitive impairment; executive functions; magnetic resonance imaging (MRI); multiple sclerosis (MS)