title: Interleukin-6 concentrations in the vitreous body of patients with retinal detachment.
abstract: OBJECTIVE
  To measure interleuquin-6 (IL-6) levels in the vitreous body of patients with retinal detachment (RD).
  
  
  METHODS
  Undiluted vitreous samples were obtained from 40 patients with no history of prior vitreous or intraocular surgery. Patients were divided into two groups: A (n=20) patients with RD and B (n=20) patients with pre-retinal macular membranes and macular holes. IL-6 was determined using radioimmunoassay.
  
  
  RESULTS
  IL-6 vitreous concentration in group A was 122.4+-16pg/mL (range 91.5-620) and in group B was 46+/-23pg/mL (range 3-150) (p <.001).
  
  
  CONCLUSIONS
  These results show that the concentration of IL-6 in the vitreous body was significantly higher in patients with RD than in the control group.
authors.affiliation: Servicio de Oftalmología, Hospital Clínico Universitario, Valladolid, España. Electronic address: victor_asensio@orangemail.es.
authors.forename: V M
authors.initials: VM
authors.lastname: Asensio-Sánchez
authors.affiliation: Servicio de Bioquímica, Hospital Medina del Campo, Valladolid, España.
authors.forename: J M
authors.initials: JM
authors.lastname: Collazos
authors.affiliation: Bioestadística, Hospital Medina del Campo , Valladolid, España.
authors.forename: M
authors.initials: M
authors.lastname: Cantón
mesh_terms: D000368:Aged; D017209:Apoptosis; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D011863:Radioimmunoassay; D012163:Retinal Detachment / Q000378:metabolism* / Q000473:pathology; D012167:Retinal Perforations / Q000378:metabolism* / Q000473:pathology; D014821:Vitrectomy; D014822:Vitreous Body / Q000737:chemistry*
chemical_list: C508600:IL6 protein, human; D015850:Interleukin-6
keywords: Agujero macular; Desprendimiento de retina; Interleuquin-6; Interleuquina-6; Macular hole; Membrana premacular; Premacular membrane; Retinal detachment; Vitreous; Vítreo