title: Short-term effect of diode laser cyclophotocoagulation on intraocular pressure: a prospective study.
abstract: BACKGROUND
  This aims to determine the immediate and short-term risk of intraocular pressure spikes following diode laser cyclophotocoagulation.
  
  
  METHODS
  This study is a prospective, consecutive cohort study in a UK teaching hospital.
  
  
  METHODS
  Fifty-three consecutive patients undergoing cyclophotocoagulation were invited to participate in this study.
  
  
  METHODS
  Intraocular pressure (IOP) measurements were taken immediately prior to cyclodiode laser, hourly for the first 3 h after laser, on the first and seventh postoperative days, and at three months following laser.
  
  
  METHODS
  Eyes experiencing intraocular pressure elevation defined at two levels (≥3 mm Hg and ≥10 mm Hg from the pretreatment level) were identified.
  
  
  RESULTS
  Seventeen eyes (34%) had an elevation in intraocular pressure (≥3 mmHg) during the first 3 h postoperatively with a mean increase of 10.3 mmHg. No preoperative or perioperative associations were found for a postcyclodiode spike within the first 3 postoperative hours.No association was found between pressure spikes and visual acuity, reduction of glaucoma medication or final postoperative intraocular pressure at 3 months. Eyes that did not have an IOP spike during the first 3 h postoperatively had a greater reduction in IOP at 3 months (15.2 mmHg vs. 10.2 mmHg; P = 0.184).
  
  
  CONCLUSIONS
  IOP spikes are common in the immediate period after cyclophotocoagulation. An elevation in IOP is noted after the first hour in the vast majority who experience a spike in the first 3 h post-procedure.
authors.affiliation: Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: Samreen
authors.initials: S
authors.lastname: Uppal
authors.affiliation: Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: Richard E
authors.initials: RE
authors.lastname: Stead
authors.affiliation: Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: Bheemanagouda B
authors.initials: BB
authors.lastname: Patil
authors.affiliation: Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: Emer
authors.initials: E
authors.lastname: Henry
authors.affiliation: Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Moodie
authors.affiliation: Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Vernon
authors.affiliation: Nottingham University Hospitals NHS Trust, Nottingham, UK.
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: King
mesh_terms: D002924:Ciliary Body / Q000601:surgery*; D005901:Glaucoma / Q000503:physiopathology / Q000601:surgery*; D006784:Hospitals, Teaching; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D017075:Laser Coagulation / Q000379:methods*; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D011446:Prospective Studies; D013997:Time Factors; D014065:Tonometry, Ocular; D014792:Visual Acuity / Q000502:physiology
keywords: cyclodiode; cyclophotocoagulation; pressure spike