title: Pulmonary Metastasis of Combined Hepatocellular and Cholangiocarcinoma: A Unique Radiographic Presentation with Air-space Consolidation Masquerading as Pneumonia and Primary Pulmonary Adenocarcinoma.
abstract: Lung metastasis showing radiographic findings of air-space consolidation is considered to be rare. This report describes the case of a man with progressive left lower lobe air-space consolidation with a history of hepatocellular carcinoma. The pulmonary lesion was initially suspected to be infection and later clinically diagnosed as primary adenocarcinoma of the lung. Although the patient was treated with systemic chemotherapy, the disease progressed very rapidly. A postmortem examination revealed that the alveolar spaces were filled with neoplastic cells subsequently proven to be metastases of combined hepatocellular and cholangiocarcinoma.
authors.affiliation: Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Ishii
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Goto
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Matsuzaki
authors.forename: Nobuya
authors.initials: N
authors.lastname: Ohishi
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Sakamoto
authors.forename: Ruri
authors.initials: R
authors.lastname: Saito
authors.forename: Keisuke
authors.initials: K
authors.lastname: Matsusaka
authors.forename: Junji
authors.initials: J
authors.lastname: Shibahara
authors.forename: Takahide
authors.initials: T
authors.lastname: Nagase
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D000368:Aged; D001650:Bile Duct Neoplasms / Q000473:pathology; D001653:Bile Ducts, Intrahepatic / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000473:pathology*; D018281:Cholangiocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary*; D008297:Male; D016609:Neoplasms, Second Primary; D011014:Pneumonia / Q000175:diagnosis; D011859:Radiography