title: Role of Endogenous Factors in Response of Erythrocyte Membrane in Patients with Cardiovascular Diseases under Conditions of Ischemic Exposure.
abstract: We studied specific features of erythrocyte membrane response to short-term occlusion of the brachial artery in patients with cardiovascular pathology. Under ischemic conditions, processes of sorption were primarily intensified in patients with effort angina and processes of hemoglobin binding with erythrocyte membrane predominated in patients with essential hypertension. These changes in the cell membrane were related to modulation of aggregation properties of erythrocytes (in patients with angina) and plasminogen activity (in patients with essential hypertension). They can also be associated with changes in glucose levels (effort angina) and uric acid (essential hypertension) whose effects can be significantly modified by other endogenous factors.
authors.affiliation: Research Center of Reconstructive and Plastic Surgery, Siberian Division of Russian Academy of Medical Sciences, Irkutsk, Russia.
authors.forename: Yu I
authors.initials: YI
authors.lastname: Pivovarov
authors.forename: E E
authors.initials: EE
authors.lastname: Kuznetsova
authors.forename: L B
authors.initials: LB
authors.lastname: Koryakina
authors.forename: V G
authors.initials: VG
authors.lastname: Gorokhova
authors.forename: T E
authors.initials: TE
authors.lastname: Kuril'skaya
mesh_terms: D000327:Adsorption; D000328:Adult; D060050:Angina, Stable / Q000097:blood*; D001132:Arm / Q000098:blood supply; D001809:Blood Viscosity; D001916:Brachial Artery; D003250:Constriction; D003327:Coronary Disease / Q000097:blood*; D004910:Erythrocyte Membrane / Q000502:physiology*; D005340:Fibrinogen / Q000032:analysis; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007511:Ischemia / Q000209:etiology; D008055:Lipids / Q000097:blood; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D009711:Nucleotides / Q000097:blood; D010958:Plasminogen / Q000032:analysis; D010973:Platelet Adhesiveness; D014841:von Willebrand Factor / Q000032:analysis
chemical_list: D006454:Hemoglobins; D008055:Lipids; D009711:Nucleotides; D014841:von Willebrand Factor; D008315:Malondialdehyde; D005340:Fibrinogen; D010958:Plasminogen