title: Aerobic glycolysis: beyond proliferation.
abstract: Aerobic glycolysis has been generally associated with cancer cell proliferation, but fascinating and novel data show that it is also coupled to a series of further cellular functions. In this Mini Review, we will discuss some recent findings to illustrate newly defined roles for this process, in particular in non-malignant cells, supporting the idea that metabolism can be considered as an integral part of cellular signaling. Consequently, metabolism should be regarded as a plastic and highly dynamic determinant of a wide range of cellular specific functions.
authors.affiliation: Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London , London , UK.
authors.forename: William
authors.initials: W
authors.lastname: Jones
authors.affiliation: Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London , London , UK.
authors.forename: Katiuscia
authors.initials: K
authors.lastname: Bianchi
keywords: aerobic glycolysis; cellular signalling; immunometabolism; non-malignant cells; proliferation