title: Peanut and tree nut allergy.
abstract: Allergy to peanut and tree nuts is a major worldwide health concern. The prevalence of these allergies may be increasing, but the reasons for these increases remain unclear. This group of foods accounts for a large proportion of severe and fatal food-allergic reactions. These allergies present most often during childhood but can occur at any age. Resolution is possible but uncommon, and frequent lifetime reactions caused by accidental ingestion are a serious problem. The major allergens of peanut and most tree nuts have been identified, allowing for insights into patient diagnoses, clinical outcomes, and potential future immunotherapies.
authors.affiliation: Division of Allergy and Clinical Immunology, Department of Pediatrics, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, N.Y., USA.
authors.forename: Amanda
authors.initials: A
authors.lastname: Cox
authors.forename: Scott H
authors.initials: SH
authors.lastname: Sicherer
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000485:Allergens / Q000009:adverse effects / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007167:Immunotherapy; D007223:Infant; D021184:Nut Hypersensitivity / Q000175:diagnosis* / Q000453:epidemiology* / Q000276:immunology / Q000628:therapy; D021183:Peanut Hypersensitivity / Q000175:diagnosis* / Q000453:epidemiology* / Q000276:immunology / Q000628:therapy
chemical_list: D000485:Allergens; D007073:Immunoglobulin E