title: Adenocarcinoma of the urethra with mucinous features.
abstract: Primary adenocarcinoma of the female urethra is a rare malignancy. Previous studies hypothesize multiple origins, including periurethral glands or intestinal metaplasia. We report a case of a 60-year-old white woman with adenocarcinoma of the urethra who initially presented with obstructive voiding complaints secondary to a urethral mass. Wide local excision revealed invasive adenocarcinoma of the urethra with mucinous features. There was intestinal metaplasia adjacent to the tumor, as well as separate identification of intestinal metaplasia along the urethra. Ultimately, the patient underwent radical cystectomy with ileal conduit urinary diversion with no evidence of recurrence, indicating the role of early identification and surgical intervention for such cases.
authors.affiliation: The University of Arizona College of Medicine, Tucson, AZ.
authors.forename: Arthi
authors.initials: A
authors.lastname: Satyanarayan
authors.affiliation: Department of Pathology, The University of Arizona Medical Center, Tucson, AZ.
authors.forename: Lucas
authors.initials: L
authors.lastname: Redd
authors.affiliation: Division of Urology, The University of Arizona Medical Center, Tucson, AZ.
authors.forename: Anthony
authors.initials: A
authors.lastname: Dyer
authors.affiliation: Division of Urology, The University of Arizona Medical Center, Tucson, AZ.
authors.forename: Andrew
authors.initials: A
authors.lastname: Wright
authors.affiliation: Division of Urology, The University of Arizona Medical Center, Tucson, AZ.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Walker
keywords: Genital tract tumor; Radical cystectomy; Skene gland; Urethra; Urethral adenocarcinoma