title: Treatment of lipoid proteinosis with ablative Er:YAG laser resurfacing.
abstract: Lipoid proteinosis (LP) is a rare autosomal recessive genodermatosis characterized by deposition of amorphous hyaline material in different parts of the body, especially the skin and mucous membranes. Disfiguring lesions predominantly affect facial appearance. There is no curative therapy and treatment options are limited to symptomatic approaches. Facial disfigurement in this disease may have an huge negative effect on the patients' psychology and quality of life. With this regard, the patients may benefit very much from symptomatic treatments. Four patients with LP were treated with Er:YAG laser to ablate disfiguring lesions on the face. Patients were followed up for 14 months to 2 years. We obtained favorable clinical and aesthetic results in all cases with Er:YAG laser treatment and did not observe any recurrences during the follow-up. Depending on our observations Er-YAG laser can be accepted as an effective tool for dermal accumulations and scars of LP with precise ablation capability and favorable esthetic results.
authors.affiliation: Dermatology Department, Gulhane School of Medicine.
authors.forename: Ercan
authors.initials: E
authors.lastname: Çalıskan
authors.affiliation: Dermatology Department, Gulhane School of Medicine.
authors.forename: Gürol
authors.initials: G
authors.lastname: Açıkgöz
authors.affiliation: Dermatology Department, Gulhane School of Medicine.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Tunca
authors.affiliation: Dermatology Department, Medical Park Hospital, Ankara, Turkey.
authors.forename: Erol
authors.initials: E
authors.lastname: Koç
authors.affiliation: Dermatology Department, Gulhane School of Medicine.
authors.forename: Ercan
authors.initials: E
authors.lastname: Arca
authors.affiliation: Dermatology Department, Gulhane School of Medicine.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Akar
mesh_terms: D000293:Adolescent; D000328:Adult; D002921:Cicatrix / Q000209:etiology / Q000517:prevention & control; D005145:Face / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D008065:Lipoid Proteinosis of Urbach and Wiethe / Q000473:pathology / Q000601:surgery*; D008297:Male; D011788:Quality of Life; D016896:Treatment Outcome; D055815:Young Adult
keywords: genetic diseases/genodermatoses; laser