title: Bone density in apheresis donors and whole blood donors.
abstract: Apheresis donation using citrate causes acute decrease in serum calcium and increase in serum parathyroid hormone. Long-term consequences, such as decrease in bone mineral density (BMD), are not known. In this study, we compared the BMD of 20 postmenopausal apheresis donors (mean donation number 115 times in up to 15 years) with that of 20 whole blood donors (for 15 years or more) aged 55-70. BMD in the lumbar spine was not lower in apheresis donors than in blood donors (mean ± SD 1.00 ± 0.18 vs. 0.92 ± 0.12, P = 0.09). In the hip, BMD was not different between the groups.
authors.affiliation: Department of Internal Medicine/Endocrinology, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: C L
authors.initials: CL
authors.lastname: Boot
authors.affiliation: Department of Transfusion Medicine, Sanquin Blood Supply, Amsterdam, The Netherlands.
authors.forename: J S
authors.initials: JS
authors.lastname: Luken
authors.affiliation: Department of Transfusion Medicine, Sanquin Blood Supply, Amsterdam, The Netherlands.
authors.forename: P J M
authors.initials: PJ
authors.lastname: van den Burg
authors.affiliation: Unit Donor Services, Sanquin Blood Supply, Nijmegen, The Netherlands.
authors.forename: W L A M
authors.initials: WL
authors.lastname: de Kort
authors.affiliation: Department of Transfusion Medicine, Sanquin Blood Supply, Amsterdam, The Netherlands.
authors.forename: M M W
authors.initials: MM
authors.lastname: Koopman
authors.affiliation: Department of Transfusion Medicine, Sanquin Blood Supply, Amsterdam, The Netherlands.
authors.forename: H
authors.initials: H
authors.lastname: Vrielink
authors.affiliation: Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: N M
authors.initials: NM
authors.lastname: van Schoor
authors.affiliation: Department of Internal Medicine/Endocrinology, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: den Heijer
authors.affiliation: Department of Internal Medicine/Endocrinology, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: P
authors.initials: P
authors.lastname: Lips
mesh_terms: D000368:Aged; D001781:Blood Component Removal; D001782:Blood Donors; D015519:Bone Density; D005260:Female; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause / Q000097:blood* / Q000502:physiology
keywords: apheresis; blood donation; bone markers; bone mineral density; citrate