title: Serrated adenoma of the gallbladder: a case report.
abstract: A case of serrated adenomatous polyp found in a cholecystectomy specimen is reported. The adenoma was built with mucosal crypts exhibiting unlocked serrations lined with up to high-grade dysplastic cells. A desmoplastic sclerotic tissue having multiple stromal hubs with branched thin spokes replaced the subjacent lamina propia, muscularis mucosae, and submucosa. The generous serrated configurations covering a multi-branched sclerotic stroma, gave the adenoma a papillary appearance. Review of the literature indicates that this appears to be the first reported case of serrated adenoma of the gallbladder.
authors.affiliation: Department of Pathology, Karolinska Institute and University Hospital, Stockholm, Sweden Carlos.Rubio@ki.se.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Rubio
mesh_terms: D000236:Adenoma / Q000150:complications / Q000473:pathology* / Q000601:surgery; D000368:Aged; D002763:Cholecystectomy; D003111:Colonic Polyps / Q000150:complications / Q000473:pathology* / Q000601:surgery; D003424:Crohn Disease / Q000150:complications / Q000473:pathology* / Q000601:surgery; D005704:Gallbladder / Q000473:pathology; D005706:Gallbladder Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male
keywords: Gallbladder; adenoma; case report; serrated