title: Low-dose computed tomographic screening for lung cancer.
abstract: Low-dose computed tomographic (LDCT) screening is now moving from clinical trials to clinical practice, following the report from the National Lung Screening Trial that LDCT screening for lung cancer can reduce the number of deaths from lung cancer by 20% in current and former smokers, ages 55 to 74 years, with a 30 pack-year smoking history. This article reviews the current evidence for screening, key elements of a successful lung cancer screening clinic, and reporting and management guidelines for LDCT screening findings.
authors.affiliation: Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA.
authors.forename: Jared D
authors.initials: JD
authors.lastname: Christensen
authors.affiliation: Department of Radiology, Wake Forest University Health Sciences Center, Medical Center Boulevard, Winston-Salem, NC 27157, USA. Electronic address: cchiles@wakehealth.edu.
authors.forename: Caroline
authors.initials: C
authors.lastname: Chiles
mesh_terms: D055088:Early Detection of Cancer / Q000379:methods*; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D011829:Radiation Dosage; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: Computed tomography (CT); Lung cancer; Screening