title: [Study on anti-tumor chemical constituents from pericarps of Juglans mandshurica].
abstract: OBJECTIVE
  To study the anti-tumor chemical components of the pericarps of Juglans mandshurica.
  
  
  METHODS
  The chemical constituents were isolated and purified by AB-8 macroporous adsorption resin, silica gel, Sephadex LH-20 columns and recrystallization. The structures were elucidated on the basis of physicochemical properties and NMR spectral data analysis.
  
  
  RESULTS
  From the pericarps of Juglans mandshurica, twelve compounds were separated and identified as 3-methoxy juglone(1), 3-ethoxy juglone(2), 1,8-di-hydroxy anthraquinone (3), juglone (4), 2α, 3α, 19α-trihydroxy ursolic acid (5), 1α, 3β-dihydroxy-olean-18-ene (6), methyl gallate (7), pterocarine(8), quercetin(9), kaempferol(10), daucosterol(11), and β-sitosterol(12).
  
  
  CONCLUSIONS
  Compounds 1 - 3 and 6 are isolated from the pericarps of Juglans mandshurica for the first time. Compounds 5 and 7 are isolated from Juglans genus for the first time.
authors.forename: Yuan-yuan
authors.initials: YY
authors.lastname: Zhou
authors.forename: Ying
authors.initials: Y
authors.lastname: Meng
authors.forename: Yan-qiu
authors.initials: YQ
authors.lastname: Jiang
authors.forename: Zhao-xi
authors.initials: ZX
authors.lastname: Liu
authors.forename: Bing-you
authors.initials: BY
authors.lastname: Yang
mesh_terms: D000880:Anthraquinones; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005707:Gallic Acid / Q000031:analogs & derivatives; D031324:Juglans / Q000737:chemistry*; D044949:Kaempferols; D009285:Naphthoquinones; D064209:Phytochemicals / Q000737:chemistry* / Q000302:isolation & purification; D012639:Seeds / Q000737:chemistry; D012855:Sitosterols; D014315:Triterpenes; D000097245:Ursolic Acid
chemical_list: D000880:Anthraquinones; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D005707:Gallic Acid; D044949:Kaempferols; D009285:Naphthoquinones; D064209:Phytochemicals; D012855:Sitosterols; D014315:Triterpenes; D000097245:Ursolic Acid; C025473:gamma-sitosterol; C052082:methyl gallate; C006552:kaempferol; C011015:lyoniside; C005134:juglone; C004315:danthron