title: A case series of 15 women inadvertently exposed to magnetic resonance imaging in the first trimester of pregnancy.
abstract: Information on the safety of first-trimester exposure to diagnostic magnetic resonance imaging (MRI) remains scarce. We are reporting a case series of 15 consecutive pregnant women who underwent an MRI scan with a 1.5-Tesla scanner of either the head (n = 5), cervical spine (n = 4), lumbar spine (n = 4), pelvis (n = 1) or knee (n = 1) in their first trimester of pregnancy (mean gestational age at exposure: 3.8 weeks). Patients were prospectively followed up until the completion of their pregnancy. Two cases received gadolinium as a contrast agent. There were 15 babies born alive. Of them, one baby was born with the left kidney not visualised by ultrasound examination, and another one with an overlapping toe in the right foot. None of these abnormalities were considered by the authors related to the MRI exposure. In conclusion, our study provides support to published preliminary evidence regarding the safety of MRI in the first-trimester pregnant women.
authors.affiliation: a The Korean Motherisk Program, Cheil General Hospital & Women's Healthcare Center , Seoul , Korea.|b Division of Maternal-Foetal Medicine, Department of Obstetrics and Gynaecology , Cheil General Hospital and Women's Healthcare Center, College of Medicine, Dankook University , Seoul , Korea.
authors.forename: J S
authors.initials: JS
authors.lastname: Choi
authors.affiliation: a The Korean Motherisk Program, Cheil General Hospital & Women's Healthcare Center , Seoul , Korea.|b Division of Maternal-Foetal Medicine, Department of Obstetrics and Gynaecology , Cheil General Hospital and Women's Healthcare Center, College of Medicine, Dankook University , Seoul , Korea.
authors.forename: H K
authors.initials: HK
authors.lastname: Ahn
authors.affiliation: a The Korean Motherisk Program, Cheil General Hospital & Women's Healthcare Center , Seoul , Korea.|b Division of Maternal-Foetal Medicine, Department of Obstetrics and Gynaecology , Cheil General Hospital and Women's Healthcare Center, College of Medicine, Dankook University , Seoul , Korea.
authors.forename: J Y
authors.initials: JY
authors.lastname: Han
authors.affiliation: b Division of Maternal-Foetal Medicine, Department of Obstetrics and Gynaecology , Cheil General Hospital and Women's Healthcare Center, College of Medicine, Dankook University , Seoul , Korea.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Han
authors.affiliation: b Division of Maternal-Foetal Medicine, Department of Obstetrics and Gynaecology , Cheil General Hospital and Women's Healthcare Center, College of Medicine, Dankook University , Seoul , Korea.
authors.forename: D O
authors.initials: DO
authors.lastname: Kwak
authors.affiliation: c PharmaReasons - Pharmacological Research & Applied Solutions , Ontario , Canada.
authors.forename: E Y
authors.initials: EY
authors.lastname: Velazquez-Armenta
authors.affiliation: c PharmaReasons - Pharmacological Research & Applied Solutions , Ontario , Canada.|d Department of Pharmacology & Toxicology , University of Toronto , ON , Canada.|e Division of Clinical Pharmacology & Toxicology, Hospital for Sick Children , Toronto , ON , Canada.
authors.forename: A A
authors.initials: AA
authors.lastname: Nava-Ocampo
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000009:adverse effects*; D011247:Pregnancy; D011261:Pregnancy Trimester, First
keywords: Diagnostic techniques and procedures; foetal development; maternal exposure