title: Detection of boronic acid derivatives in cells using a fluorescent sensor.
abstract: The detection of boron-containing compounds requires very expensive facilities and/or tedious sample pretreatments. In an effort to develop a convenient detection method for boronic acid derivatives, boron chelating-ligands were synthesized for use as fluorescent sensors. In this paper, the synthesis and properties of fluorescent sensors for boronic acid derivatives are reported.
authors.affiliation: Research Center of Boron Neutron Capture Therapy, Research Organization for the 21st Century, Osaka Prefecture University, 1-1 Gakuen-cho, Nakaku, Sakai, Japan. y0shi_hattori@riast.osakafu-u.ac.jp.
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Hattori
authors.forename: Miki
authors.initials: M
authors.lastname: Ishimura
authors.forename: Youichirou
authors.initials: Y
authors.lastname: Ohta
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takenaka
authors.forename: Tsubasa
authors.initials: T
authors.lastname: Watanabe
authors.forename: Hiroki
authors.initials: H
authors.lastname: Tanaka
authors.forename: Koji
authors.initials: K
authors.lastname: Ono
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Kirihata
mesh_terms: D000970:Antineoplastic Agents / Q000032:analysis*; D001895:Boron / Q000737:chemistry*; D001896:Boron Compounds / Q000032:analysis*; D001897:Boronic Acids / Q000032:analysis*; D000069286:Bortezomib / Q000032:analysis*; D045744:Cell Line, Tumor; D002614:Chelating Agents / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D061848:Optical Imaging / Q000379:methods; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000032:analysis; D013050:Spectrometry, Fluorescence / Q000379:methods
chemical_list: D000970:Antineoplastic Agents; D001896:Boron Compounds; D001897:Boronic Acids; D002614:Chelating Agents; D005456:Fluorescent Dyes; D010649:Phenylalanine; D000069286:Bortezomib; D001895:Boron; C033685:4-boronophenylalanine