title: Cholangiographic characteristics of common bile duct dilatation in children.
abstract: OBJECTIVE
  To investigate whether children with congenital common bile duct dilatation (CBDD) differ from children with obstructive CBDD in cholangiographic characteristics.
  
  
  METHODS
  In this retrospective cohort study, the baseline data and the results of imaging analyses were reviewed among children who had endoscopic retrograde cholangiopancreatography (ERCP) due to CBDD. ERCP was performed on all pediatric patients by experienced pediatric endoscopists. The maximal transverse diameter of the common bile duct (CBD) was measured on ERCP. To assess whether age-adjusted CBDD could be used for differential diagnosis, a CBDD severity index (SI) was calculated by dividing the measured CBD diameter by the age-corrected maximal diameter of a normal CBD.
  
  
  RESULTS
  A retrospective medical chart review revealed that 85 consecutive children under 16 years of age with hepatobiliary disease and CBDD were referred to Seoul Asan Medical Center. Fifty-five (64.7%) children had congenital CBDD and 30 (35.3%) had obstructive CBDD. The two groups did not differ significantly in terms of clinical characteristics except for sex. The congenital and obstructive CBDD groups did not differ significantly in terms of mean CBD diameter (19.3 ± 9.6 mm vs 12.2 ± 4.1 mm, P > 0.05). However, congenital CBDD cases had a significantly higher mean SI than obstructive CBDD cases (3.62 ± 1.64 vs 1.98 ± 0.71, P = 0.01). In multivariate analysis, an SI value ≥ 2.32 and comorbidity with anomalous union of pancreaticobiliary duct (APBDU) in ERCP independently predicted congenital CBDD.
  
  
  CONCLUSIONS
  Measuring the CBD may aid the differential diagnosis of both CBDD and APBDU in children.
authors.affiliation: Seak Hee Oh, Soo-Hee Chang, Hyun Jin Kim, Jin Min Cho, Kyung Mo Kim, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
authors.forename: Seak Hee
authors.initials: SH
authors.lastname: Oh
authors.affiliation: Seak Hee Oh, Soo-Hee Chang, Hyun Jin Kim, Jin Min Cho, Kyung Mo Kim, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
authors.forename: Soo-Hee
authors.initials: SH
authors.lastname: Chang
authors.affiliation: Seak Hee Oh, Soo-Hee Chang, Hyun Jin Kim, Jin Min Cho, Kyung Mo Kim, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
authors.forename: Hyun Jin
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Seak Hee Oh, Soo-Hee Chang, Hyun Jin Kim, Jin Min Cho, Kyung Mo Kim, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
authors.forename: Jin Min
authors.initials: JM
authors.lastname: Cho
authors.affiliation: Seak Hee Oh, Soo-Hee Chang, Hyun Jin Kim, Jin Min Cho, Kyung Mo Kim, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
authors.forename: Ji-Hee
authors.initials: JH
authors.lastname: Hwang
authors.affiliation: Seak Hee Oh, Soo-Hee Chang, Hyun Jin Kim, Jin Min Cho, Kyung Mo Kim, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
authors.forename: Jung-Man
authors.initials: JM
authors.lastname: Namgoong
authors.affiliation: Seak Hee Oh, Soo-Hee Chang, Hyun Jin Kim, Jin Min Cho, Kyung Mo Kim, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
authors.forename: Dae Yeon
authors.initials: DY
authors.lastname: Kim
authors.affiliation: Seak Hee Oh, Soo-Hee Chang, Hyun Jin Kim, Jin Min Cho, Kyung Mo Kim, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
authors.forename: Young-Ah
authors.initials: YA
authors.lastname: Cho
authors.affiliation: Seak Hee Oh, Soo-Hee Chang, Hyun Jin Kim, Jin Min Cho, Kyung Mo Kim, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
authors.forename: Chong Hyun
authors.initials: CH
authors.lastname: Yoon
authors.affiliation: Seak Hee Oh, Soo-Hee Chang, Hyun Jin Kim, Jin Min Cho, Kyung Mo Kim, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul 138-736, South Korea.
authors.forename: Kyung Mo
authors.initials: KM
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D002760:Cholangiopancreatography, Endoscopic Retrograde; D015529:Choledochal Cyst / Q000000981:diagnostic imaging*; D042883:Choledocholithiasis / Q000000981:diagnostic imaging*; D002779:Cholestasis / Q000000981:diagnostic imaging*; D003135:Common Bile Duct / Q000002:abnormalities / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D004108:Dilatation, Pathologic; D005260:Female; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D056910:Republic of Korea; D012189:Retrospective Studies
keywords: Children; Choledochal cyst; Choledolithiasis; Common bile duct; Endoscopic retrograde cholangiopancreatography