title: Synthesis of Diaryliodonium Salts Having Pentafluorosulfanylarenes and Their Application to Electrophilic Pentafluorosulfanylarylation of C-, O-, N-, and S-Nucleophiles.
abstract: Novel reagents for the electrophilic introduction of pentafluorosulfanyl (SF5) arenes into target molecules are disclosed. Unsymmetrical diaryliodonium salts 1 having SF5-arenes were synthesized by a one-pot process from iodo-SF5-benzenes 2 in good yields. The SF5-aryliodonium salts 1 were found to be efficient for the electrophilic SF5-arylation of carbon and heterocentered nucleophiles to furnish the corresponding substituted SF5-arenes in good to high yields.
authors.affiliation: †Department of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan.
authors.forename: Kohei
authors.initials: K
authors.lastname: Matsuzaki
authors.affiliation: †Department of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan.
authors.forename: Kenta
authors.initials: K
authors.lastname: Okuyama
authors.affiliation: †Department of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan.
authors.forename: Etsuko
authors.initials: E
authors.lastname: Tokunaga
authors.affiliation: ‡Pharmaceutical Division, Ube Industries, Ltd., Seavans North Building 1-2-1 Shibaura, Minato-ku, Tokyo 105-8449, Japan.
authors.forename: Norimichi
authors.initials: N
authors.lastname: Saito
authors.affiliation: §Rigaku Corporation, 3-9-12 Mastubara-cho, Akishima, Tokyo 196-8666, Japan.
authors.forename: Motoo
authors.initials: M
authors.lastname: Shiro
authors.affiliation: †Department of Nanopharmaceutical Sciences, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan.
authors.forename: Norio
authors.initials: N
authors.lastname: Shibata
mesh_terms: D002384:Catalysis; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D007202:Indicators and Reagents / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*; D015394:Molecular Structure; D009861:Onium Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D012492:Salts / Q000737:chemistry*
chemical_list: D006845:Hydrocarbons, Fluorinated; D007202:Indicators and Reagents; D009861:Onium Compounds; D012492:Salts; D007455:Iodine