title: Somatostatin Receptors in an Anaplastic Oligodendroglioma Relapse Evidenced By 68Ga DOTANOC PET/CT.
abstract: Six years ago, a right frontal lobe anaplastic oligodendroglioma negative for AE1/AE3 and HBM-45, positive for 1p/19q deletion, EMA, GFAP, and synaptophysin was excised from a 50-year-old woman. Treatments that followed were radiation therapy, and surgery plus radiation therapy and temozolomide for a relapse with an early partial response, followed by disease progression. In the middle of last year, ⁶⁸Ga-DOTANOC PET/CT was carried out to evaluate the possibility of treatment with peptide receptor radionuclide therapy. The examination revealed a grossly round-shaped uptake corresponding to the surgical wall, with some smaller uptakes disseminated in different parts of the brain.
authors.affiliation: From the *Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy; and †Department of Nuclear Medicine, SS. Antonio e Biagio e C. Arrigo City Hospital, Alessandria Italy.
authors.forename: Giordano
authors.initials: G
authors.lastname: Savelli
authors.forename: Alfredo
authors.initials: A
authors.lastname: Muni
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000235:genetics; D005260:Female; D017353:Gene Deletion; D006801:Humans; D008875:Middle Aged; D064847:Multimodal Imaging; D009837:Oligodendroglioma / Q000000981:diagnostic imaging* / Q000235:genetics; D009942:Organometallic Compounds; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: C504894:68Ga-DOTANOC; D009942:Organometallic Compounds; D019275:Radiopharmaceuticals