title: Dynamics of the Light-Dependent Transition of Plant Peroxisomes.
abstract: Peroxisomes are present in almost all plant cells. These organelles are involved in various metabolic processes, such as lipid catabolism and photorespiration. A notable feature of plant peroxisomes is their flexible adaptive responses to environmental conditions such as light. When plants shift from heterotrophic to autotrophic growth during the post-germinative stage, peroxisomes undergo a dynamic response, i.e. enzymes involved in lipid catabolism are replaced with photorespiratory enzymes. Although the detailed molecular mechanisms underlying the functional transition of peroxisomes have previously been unclear, recent analyses at the cellular level have enabled this detailed machinery to be characterized. During the functional transition, obsolete enzymes are degraded inside peroxisomes by Lon protease, while newly synthesized enzymes are transported into peroxisomes. In parallel, mature and oxidized peroxisomes are eliminated via autophagy; this functional transition occurs in an efficient manner. Moreover, it has become clear that quality control mechanisms are important for the peroxisomal response to environmental stimuli. In this review, we highlight recent advances in elucidating the molecular mechanisms required for the regulation of peroxisomal roles in response to changes in environmental conditions.
authors.affiliation: Graduate School of Science, Kyoto University, Kyoto, 606-8502 Japan.
authors.forename: Shino
authors.initials: S
authors.lastname: Goto-Yamada
authors.affiliation: Laboratory of Biological Diversity, Department of Evolutionary Biology and Biodiversity, National Institute for Basic Biology, Okazaki, 444-8585 Japan Department of Basic Biology, School of Life Science, SOKENDAI (The Graduate University for Advanced Studies), Okazaki, 444-8585 Japan.
authors.forename: Shoji
authors.initials: S
authors.lastname: Mano
authors.affiliation: Graduate School of Science, Kyoto University, Kyoto, 606-8502 Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Yamada
authors.affiliation: Department of Applied Biological Chemistry, Faculty of Agriculture, Niigata University, Niigata, 950-2181 Japan.
authors.forename: Kazusato
authors.initials: K
authors.lastname: Oikawa
authors.affiliation: Graduate School of Materials Science, Nara Institute of Science and Technology, Ikoma, 630-0192 Japan.
authors.forename: Yoichiroh
authors.initials: Y
authors.lastname: Hosokawa
authors.affiliation: Graduate School of Science, Kyoto University, Kyoto, 606-8502 Japan.
authors.forename: Ikuko
authors.initials: I
authors.lastname: Hara-Nishimura
authors.affiliation: Department of Cell Biology, National Institute for Basic Biology, Okazaki, 444-8585 Japan Present address: Research Enhancement Strategy Office, National Institute for Basic Biology, Okazaki, 444-8585 Japan. mikosome@nibb.ac.jp.
authors.forename: Mikio
authors.initials: M
authors.lastname: Nishimura
mesh_terms: D001343:Autophagy / Q000528:radiation effects; D008027:Light; D008954:Models, Biological; D010084:Oxidation-Reduction / Q000528:radiation effects; D020675:Peroxisomes / Q000201:enzymology / Q000378:metabolism / Q000528:radiation effects*; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000378:metabolism / Q000528:radiation effects*; D049070:Protease La / Q000378:metabolism*; D021381:Protein Transport / Q000528:radiation effects; D059748:Proteolysis / Q000528:radiation effects
chemical_list: D010940:Plant Proteins; D049070:Protease La
keywords: Autophagy; Environmental change; Functional transition of peroxisomes; Light; Peroxisome; Protease