title: [Active interventions in hypercholesteroloemia patients with high cardiovascular risk in primary care; estudio ESPROCOL].
abstract: BACKGROUND
  Hypercholesterolemia is a major modifiable risk factors for cardiovascular disease (CVD). Its reduction reduces morbidity and mortality from ischemic heart disease and CVD in general, primary prevention and secondary prevention especially.
  
  
  OBJECTIVE
  To determine whether a notarized and intensive clinical practice can overcome inertia and achieve the therapeutic goal (OT) LDL-C <100 mg/dL in high-risk patients attended in Primary Care (PC) in our country.
  
  
  METHODS
  Epidemiological, prospective, multicenter study conducted in centers of different ACs By AP consecutive sampling 310 patients at high cardiovascular risk (diabetic or established CVD) previously treated with statins, which did not reach the OT included c-LDL.
  
  
  RESULTS
  The study subjects had a mean age of 65.2 years, of which 60.32% were male. The 41.64% had a previous EVC, acute myocardial infarction (20.33%), angina (16.07%), stroke/TIA (9.19%), arthropathy (5.25%), diabetes (70.87%), hypertension (71.01%), and abdominal obesity (69.62%). The 43.57% (95% CI: 37,21; 50,08) of patients who performed the 2nd visit (241) got the OT. 62.50% (95% CI: 55.68, 68.98) of those who took the 3rd (216) got the OT. Finally, 77.56% (95% CI: 72.13, 83.08) patients who performed the last visit (205) got the OT. Throughout the study there was a reduction in LDL-C levels from 135.6 mg/dL at baseline, 107.4 mg dL in the 2nd visit, 97.3 mg/dL in the 3rd visit, up to 90.7 mg/dL at the final visit (p < 0.0001). The increase in HDL-C from baseline (50.9 mg/dL) and final (53.6 mg/dL) was also significant (p = 0.013).
  
  
  CONCLUSIONS
  The reassessment and intensification of treatment in patients at high cardiovascular risk treated in primary care, applying the indications of the guides, achieves the OT in more than three quarters of the previously uncontrolled within half a year. These results should encourage us to overcome the therapeutic inertia in the control of CVD by early and energetic performance against hypercholesterolemia.
authors.affiliation: Profesor Asociado de Medicina. Universidad Castilla-La Mancha.. pjtarraga@sescam.jccm.es.
authors.forename: Pedro J
authors.initials: PJ
authors.lastname: Tárraga López
authors.affiliation: Centro de Salud Condesa. Sacyl, León.. pjtarraga@sescam.jccm.es.
authors.forename: F J
authors.initials: FJ
authors.lastname: García-Norro Herreros
authors.affiliation: DUE Residencia Geriátrica Los Álamos de Albacete.. pjtarraga@sescam.jccm.es.
authors.forename: Loreto
authors.initials: L
authors.lastname: Tárraga Marcos
authors.affiliation: Coordinador Médico Centro Salud Zona 7, Albacete.. pjtarraga@sescam.jccm.es.
authors.forename: Juan
authors.initials: J
authors.lastname: Solera Albero
authors.affiliation: Centro de Salud Villanueva de la Cañada, Madrid.. pjtarraga@sescam.jccm.es.
authors.forename: Esteban
authors.initials: E
authors.lastname: González López
authors.affiliation: Centro de Salud Pinto, Madrid.. pjtarraga@sescam.jccm.es.
authors.forename: Antonio
authors.initials: A
authors.lastname: Ruiz García
authors.affiliation: Centro de Salud Vilarreal.. pjtarraga@sescam.jccm.es.
authors.forename: Vicente
authors.initials: V
authors.lastname: Pallarés Carratalá
authors.affiliation: Centro de Salud Munera, Albacete.. pjtarraga@sescam.jccm.es.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Castro Navarro
authors.affiliation: Especialista Medicina Familiar y Comunitaria Area Básica de Salud Abrera.. pjtarraga@sescam.jccm.es.
authors.forename: Josep
authors.initials: J
authors.lastname: Alins Presas
authors.affiliation: Jefe Medicina Interna Hospital Igualada, España.. pjtarraga@sescam.jccm.es.
authors.forename: Josefa María
authors.initials: JM
authors.lastname: Panisello Royo
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000401:mortality / Q000517:prevention & control*; D005260:Female; D006040:Goals; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011320:Primary Health Care; D011446:Prospective Studies; D012308:Risk Management; D013030:Spain / Q000453:epidemiology