title: Click-engineered, bioresponsive, drug-loaded PEG spheres.
abstract: A click-chemistry approach to synthesize bioresponsive poly(ethylene glycol acrylate) particles is described. The particles are loaded with a model anticancer drug (doxorubicin, DOX), and undergo simultaneous particle deconstruction and DOX release upon specific activation by the simulated environment of the cellular cytoplasm.
authors.affiliation: Centre for Nanoscience and Nanotechnology (CNST) Department of Chemical and Biomolecular Engineering The University of Melbourne Victoria, 3010 (Australia).
authors.forename: Heng Pho
authors.initials: HP
authors.lastname: Yap
authors.affiliation: Centre for Nanoscience and Nanotechnology (CNST) Department of Chemical and Biomolecular Engineering The University of Melbourne Victoria, 3010 (Australia).
authors.forename: Angus P R
authors.initials: AP
authors.lastname: Johnston
authors.affiliation: Centre for Nanoscience and Nanotechnology (CNST) Department of Chemical and Biomolecular Engineering The University of Melbourne Victoria, 3010 (Australia).
authors.forename: Georgina K
authors.initials: GK
authors.lastname: Such
authors.affiliation: Centre for Nanoscience and Nanotechnology (CNST) Department of Chemical and Biomolecular Engineering The University of Melbourne Victoria, 3010 (Australia).
authors.forename: Yan
authors.initials: Y
authors.lastname: Yan
authors.affiliation: Centre for Nanoscience and Nanotechnology (CNST) Department of Chemical and Biomolecular Engineering The University of Melbourne Victoria, 3010 (Australia). fcaruso@unimelb.edu.au.
authors.forename: Frank
authors.initials: F
authors.lastname: Caruso
keywords: Layer‐by‐layer assembly; click chemistry; drug delivery; polymer capsules