title: Influence of high intensity focused ultrasound (HIFU) treatment to the pancreatic function in pancreatic cancer patients.
abstract: Present study was designed to investigate the pancreatic endocrine and exocrine function damage after High Intensity Focused Ultrasound (HIFU) therapy in patients with advanced pancreatic cancer. It was a retrospective analysis of blood glucose and amylase changes in 59 advanced pancreatic cancer patients treated with HIFU from 2010 February to 2014 January. The mean glucose and amylase before HIFU treatment were 6.02mmol/L and 59.17 U/L respectively. After HIFU treatment, it was shown that the mean glucose and amylase levels were 5.66mmol/L and 57.86/L respectively. There was no statistical significance between them. No acute pancreatitis was observed. The endocrine and exocrine function of pancreatic cancer patients was not damaged by HIFU treatment. HIFU treatment for the pancreatic cancer patients seems to be safe.
authors.affiliation: Department of Surgical Oncology, the Second Affiliated Hospital, Zhejiang University School of Medicine, China.
authors.forename: Yulan
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Department of Surgical Oncology, the Second Affiliated Hospital, Zhejiang University School of Medicine, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Ying
authors.affiliation: Department of Surgical Oncology, the Second Affiliated Hospital, Zhejiang University School of Medicine, China.
authors.forename: Xiaoye
authors.initials: X
authors.lastname: Hu
authors.affiliation: Department of medical Oncology, the Second Affiliated Hospital, Zhejiang University School of Medicine, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
authors.affiliation: Department of medical Oncology, the Second Affiliated Hospital, Zhejiang University School of Medicine, China.
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Fang
authors.affiliation: Department of Computer Science and Engineering, Zhejiang University College of City, China.
authors.forename: Minghui
authors.initials: M
authors.lastname: Wu
authors.affiliation: College of Computer Science, Zhejiang University, China.
authors.forename: Tian Zhou
authors.initials: TZ
authors.lastname: Chen
authors.affiliation: Department of medical Oncology, the Second Affiliated Hospital, Zhejiang University School of Medicine, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Shen
mesh_terms: D000328:Adult; D000368:Aged; D000681:Amylases / Q000097:blood; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D005260:Female; D057086:High-Intensity Focused Ultrasound Ablation / Q000009:adverse effects; D006801:Humans; D007515:Islets of Langerhans / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D046790:Pancreas, Exocrine / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D010190:Pancreatic Neoplasms / Q000097:blood / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D010195:Pancreatitis / Q000097:blood / Q000209:etiology; D061214:Patient Safety; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D000681:Amylases