title: Planar Pol(o)arity.
abstract: Asymmetric localization of planar cell polarity (PCP) proteins is essential for tissue integrity, but how asymmetric localization is regulated during cell division is not known. In this issue of Developmental Cell, Shrestha et al. (2015) show that mitotic Polo-like kinase 1 (Plk1) links internalization of PCP proteins to cell-cycle progression.
authors.affiliation: Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.
authors.forename: Jakub
authors.initials: J
authors.lastname: Sedzinski
authors.affiliation: Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA; HHMI, Chevy Chase, MD 20815-6789, USA. Electronic address: wallingford@austin.utexas.edu.
authors.forename: John
authors.initials: J
authors.lastname: Wallingford
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins / Q000378:metabolism*; D016764:Cell Polarity / Q000502:physiology*; D011992:Endosomes / Q000378:metabolism*; D006801:Humans; D015603:Keratinocytes / Q000378:metabolism*; D008938:Mitosis / Q000502:physiology*; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism*
chemical_list: D018797:Cell Cycle Proteins; D011518:Proto-Oncogene Proteins; D043562:Receptors, G-Protein-Coupled; D017346:Protein Serine-Threonine Kinases