title: Relationship of menstrual cycle and vaginal infection in female rhesus macaques challenged with repeated, low doses of SIVmac251.
abstract: Varying susceptibility during menstrual cycling could be a factor for S(H)IV infection risk in female rhesus macaques. We retrospectively determined vaginal SIV infection time points relative to the menstrual cycle in a group of rhesus macaques (n=11) enrolled in an HIV transmission trial. Eight of nine rhesus macaques became infected around menstruation time.
authors.affiliation: Total Solutions, Atlanta, GA, USA.
authors.forename: Monica R
authors.initials: MR
authors.lastname: Morris
authors.affiliation: Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Siddappa N
authors.initials: SN
authors.lastname: Byrareddy
authors.affiliation: Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Francois
authors.initials: F
authors.lastname: Villinger
authors.affiliation: Laboratory Branch, Division HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control, Atlanta, GA, USA.
authors.forename: Tara C
authors.initials: TC
authors.lastname: Henning
authors.affiliation: Laboratory Branch, Division HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control, Atlanta, GA, USA.
authors.forename: Katherine
authors.initials: K
authors.lastname: Butler
authors.affiliation: Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Aftab A
authors.initials: AA
authors.lastname: Ansari
authors.affiliation: Laboratory Branch, Division HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control, Atlanta, GA, USA.
authors.forename: Janet M
authors.initials: JM
authors.lastname: McNicholl
authors.affiliation: Laboratory Branch, Division HIV/AIDS Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control, Atlanta, GA, USA.
authors.forename: Ellen N
authors.initials: EN
authors.lastname: Kersh
mesh_terms: D000818:Animals; D005260:Female; D008253:Macaca mulatta; D008597:Menstrual Cycle; D012189:Retrospective Studies; D016097:Simian Acquired Immunodeficiency Syndrome / Q000821:virology*; D015302:Simian Immunodeficiency Virus / Q000502:physiology*; D014621:Vagina / Q000821:virology*
keywords: SIV; menstrual cycle; progesterone; rhesus macaque