title: UKF-based closed loop iterative learning control of epileptiform wave in a neural mass model.
abstract: A novel closed loop control framework is proposed to inhibit epileptiform wave in a neural mass model by external electric field, where the unscented Kalman filter method is used to reconstruct dynamics and estimate unmeasurable parameters of the model. Specifically speaking, the iterative learning control algorithm is introduced into the framework to optimize the control signal. In the proposed method, the control effect can be significantly improved based on the observation of the past attempts. Accordingly, the proposed method can effectively suppress the epileptiform wave as well as showing robustness to noises and uncertainties. Lastly, the simulation is carried out to illustrate the feasibility of the proposed method. Besides, this work shows potential value to design model-based feedback controllers for epilepsy treatment.
authors.affiliation: School of Electrical Engineering and Automation, Tianjin University, Tianjin, 300072 People's Republic of China.
authors.forename: Bonan
authors.initials: B
authors.lastname: Shan
authors.affiliation: School of Electrical Engineering and Automation, Tianjin University, Tianjin, 300072 People's Republic of China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Wang
authors.affiliation: School of Electrical Engineering and Automation, Tianjin University, Tianjin, 300072 People's Republic of China.
authors.forename: Bin
authors.initials: B
authors.lastname: Deng
authors.affiliation: School of Electrical Engineering and Automation, Tianjin University, Tianjin, 300072 People's Republic of China.
authors.forename: Xile
authors.initials: X
authors.lastname: Wei
authors.affiliation: School of Electrical Engineering and Automation, Tianjin University, Tianjin, 300072 People's Republic of China.
authors.forename: Haitao
authors.initials: H
authors.lastname: Yu
authors.affiliation: School of Automation and Electrical Engineering, Tianjin University of Technology and Education, Tianjin, 300222 People's Republic of China.
authors.forename: Huiyan
authors.initials: H
authors.lastname: Li
keywords: Epilepsy; Iterative learning control; Neural mass model; UKF