title: Primordial Influence of Post-operative Compliance on Weight Loss After Adolescent Laparoscopic Adjustable Gastric Banding.
abstract: BACKGROUND
  Accumulating evidence suggests that the benefits seen in adult bariatric surgery can be reproduced in adolescents. In contrast with North America, bariatric surgery in adolescents is still not well accepted in Europe and indications and protocols have still to be formulated.
  
  
  METHODS
  This prospective study tested the gastric banding procedure in 49 patients operated in a single French institution since 2008. The mean age at surgery was 16.2 ± 0.9 years with a weight of 118.8 ± 22.3 kg and body mass index of 42.5 ± 5.9 kg/m(2).
  
  
  RESULTS
  At 6, 12 and 24 months after surgery, weight was 103.7 ± 20.8 kg, 98.7 ± 21 kg and 93.6 ± 19.3 kg, respectively (p < 0.001), corresponding to excess weight loss (EWL) of 31.6 ± 17.2 %, 41.8 ± 21.4 % and 59.1 ± 24.9 % (p < 0.001), respectively. Multivariate analysis showed that the number of consultations per year was the only variable significantly associated to weight loss. Metabolic disorders were corrected, with a decreased prevalence of insulin resistance from 100 to 17 % and normalisation of homeostasis model assessment-insulin resistance (HOMA-IR) at 24 months (2.09 ± 0.95). Band-related complications were five slippages, one psychological intolerance and two ports repositioning. Six patients (12 %) had the device explanted. The death of a patient was an exceptionally severe adverse event.
  
  
  CONCLUSIONS
  Given frequent follow-up support by a multidisciplinary team, laparoscopic adjustable gastric banding (LAGB) surgery in adolescent results in sustained weight loss. However, even exceptional, potentially serious complications are possible and long-term follow-up is needed to evaluate the risk/benefit ratio at 5 or 10 years after LAGB surgery.
authors.affiliation: AP-HP, Hôpital Necker-Enfants Malades, Service de Chirurgie Pédiatrique Viscérale, 149 rue de Sevres, 75015, Paris, France. naziha.khen-dunlop@nck.aphp.fr.|Université Paris Descartes, Paris, France. naziha.khen-dunlop@nck.aphp.fr.
authors.forename: Naziha
authors.initials: N
authors.lastname: Khen-Dunlop
authors.affiliation: AP-HP, Hôpital Necker-Enfants malades, Service de Gastroenterologie et Nutrition Pédiatrique, Paris, France. Myriam.dabbas@nck.aphp.fr.
authors.forename: Myriam
authors.initials: M
authors.lastname: Dabbas
authors.affiliation: AP-HP, Hôpital Bicêtre, Unité Médico-chirurgicale Obésité de l'Adolescent, Service de Médecine des Adolescents, Le Kremlin Bicêtre, France. gianpaolo.defilipo@bct.aphp.fr.
authors.forename: Gianpaolo
authors.initials: G
authors.lastname: De Filippo
authors.affiliation: AP-HP, Hôpital Necker-Enfants Malades, Département de Biostatistiques, Paris, France. jean-philippe.jais@nck.aphp.fr.|Université Paris Descartes, Paris, France. jean-philippe.jais@nck.aphp.fr.
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Jais
authors.affiliation: AP-HP, Hôpital Necker-Enfants Malades, Service de Chirurgie Pédiatrique Viscérale, 149 rue de Sevres, 75015, Paris, France. erik.hervieux@nck.aphp.fr.
authors.forename: Erik
authors.initials: E
authors.lastname: Hervieux
authors.affiliation: AP-HP, Hôpital Necker-Enfants Malades, Départment d'Anesthésie et Réanimation, Paris, France. caroline.telion@nck.aphp.fr.
authors.forename: Caroline
authors.initials: C
authors.lastname: Télion
authors.affiliation: AP-HP, Hôpital Européen Georges Pompidou, Service de Chirurgie Générale, Paris, France. jean-marc.chevallier@egp.aphp.fr.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Chevallier
authors.affiliation: AP-HP, Hôpital Necker-Enfants Malades, Service de Chirurgie Pédiatrique Viscérale, 149 rue de Sevres, 75015, Paris, France. jean-luc.michel@chu-reunion.fr.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Michel
authors.affiliation: AP-HP, Hôpital Necker-Enfants Malades, Service de Chirurgie Pédiatrique Viscérale, 149 rue de Sevres, 75015, Paris, France. yves.aigrain@nck.aphp.fr.|Université Paris Descartes, Paris, France. yves.aigrain@nck.aphp.fr.
authors.forename: Yves
authors.initials: Y
authors.lastname: Aigrain
authors.affiliation: AP-HP, Hôpital Bicêtre, Service d'Endocrinologie et Diabétologie Pédiatrique, Le Kremlin Bicêtre, France. pierre.bougneres@inserm.fr.
authors.forename: Pierre
authors.initials: P
authors.lastname: Bougnères
authors.affiliation: AP-HP, Hôpital Necker-Enfants malades, Service de Gastroenterologie et Nutrition Pédiatrique, Paris, France. olivier.goulet@nck.aphp.fr.|Université Paris Descartes, Paris, France. olivier.goulet@nck.aphp.fr.
authors.forename: Olivier
authors.initials: O
authors.lastname: Goulet
authors.affiliation: AP-HP, Hôpital Necker-Enfants Malades, Service de Chirurgie Pédiatrique Viscérale, 149 rue de Sevres, 75015, Paris, France. yann.revillon@nck.aphp.fr.|Université Paris Descartes, Paris, France. yann.revillon@nck.aphp.fr.
authors.forename: Yann
authors.initials: Y
authors.lastname: Révillon
mesh_terms: D000293:Adolescent; D005260:Female; D005500:Follow-Up Studies; D005602:France; D015391:Gastroplasty; D006801:Humans; D007333:Insulin Resistance; D010535:Laparoscopy; D008297:Male; D015999:Multivariate Analysis; D009767:Obesity, Morbid / Q000601:surgery; D010349:Patient Compliance; D011446:Prospective Studies; D012017:Referral and Consultation / Q000706:statistics & numerical data; D015431:Weight Loss
keywords: Adolescent; Bariatric surgery; Complications; LAGB; Obesity; Paediatrics; Results; Teen