title: Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat.
abstract: Fusarium head blight (FHB) and Septoria tritici blotch (STB) severely impair wheat production. With the aim to further elucidate the genetic architecture underlying FHB and STB resistance, we phenotyped 1604 European wheat hybrids and their 135 parental lines for FHB and STB disease severities and determined genotypes at 17,372 single-nucleotide polymorphic loci.
  
  
  
  Cross-validated association mapping revealed the absence of large effect QTL for both traits. Genomic selection showed a three times higher prediction accuracy for FHB than STB disease severity for test sets largely unrelated to the training sets.
  
  
  
  Our findings suggest that the genetic architecture is less complex and, hence, can be more properly tackled to perform accurate prediction for FHB than STB disease severity. Consequently, FHB disease severity is an interesting model trait to fine-tune genomic selection models exploiting beyond relatedness also knowledge of the genetic architecture.
authors.affiliation: Department of Cytogenetics and Genome Analysis, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Gatersleben, Germany. mirdita@ipk-gatersleben.de.
authors.forename: Vilson
authors.initials: V
authors.lastname: Mirdita
authors.affiliation: Department of Cytogenetics and Genome Analysis, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Gatersleben, Germany. liug@ipk-gatersleben.de.
authors.forename: Guozheng
authors.initials: G
authors.lastname: Liu
authors.affiliation: Department of Cytogenetics and Genome Analysis, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Gatersleben, Germany. zhao@ipk-gatersleben.de.
authors.forename: Yusheng
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: State Plant Breeding Institute, University of Hohenheim, 70593, Stuttgart, Germany. thomas.miedaner@uni-hohenheim.de.
authors.forename: Thomas
authors.initials: T
authors.lastname: Miedaner
authors.affiliation: State Plant Breeding Institute, University of Hohenheim, 70593, Stuttgart, Germany. friedrich.longin@uni-hohenheim.de.
authors.forename: C Friedrich H
authors.initials: CF
authors.lastname: Longin
authors.affiliation: International Maize and Wheat Improvement Center (CIMMYT), P. O. Box 1041-00621, Nairobi, Kenya. M.Gowda@cgiar.org.
authors.forename: Manje
authors.initials: M
authors.lastname: Gowda
authors.affiliation: Department of Cytogenetics and Genome Analysis, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Gatersleben, Germany. mette@ipk-gatersleben.de.
authors.forename: Michael Florian
authors.initials: MF
authors.lastname: Mette
authors.affiliation: Department of Cytogenetics and Genome Analysis, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), 06466, Gatersleben, Germany. reif@ipk-gatersleben.de.
authors.forename: Jochen C
authors.initials: JC
authors.lastname: Reif
mesh_terms: D001203:Ascomycota / Q000502:physiology*; D002874:Chromosome Mapping; D060467:Disease Resistance / Q000235:genetics*; D005060:Europe; D005670:Fusarium / Q000502:physiology*; D005838:Genotype; D010641:Phenotype; D010935:Plant Diseases / Q000209:etiology / Q000235:genetics* / Q000382:microbiology; D020641:Polymorphism, Single Nucleotide; D040641:Quantitative Trait Loci; D014908:Triticum / Q000235:genetics* / Q000382:microbiology