title: High bacterial titers in urine are predictive of abnormal postvoid residual urine in patients with urinary tract infection.
abstract: Urine bacterial titers (BTs) are influenced by bacterial and host factors. The impact of an abnormal postvoid residual (PVR) on BT in urine was investigated. A total of 103 inpatients with a urine growing Enterobacteriacae (≥ 10(2) CFU/mL) and a PVR measure were analyzed, mostly female (62%), elderly (mean age: 72 years), with urinary tract infection (25% of asymptomatic bacteriuria) due to Escherichia coli (85%). Fifty-two subjects (56%) had BT ≥ 10(6) CFU/mL; 48 (53%) had a PVR ≤ 100 mL, while 26 (25%) had a PVR >250 mL. PVR increased with BT, and a significant (P<0.0001) threshold was reached for 10(6) CFU/mL: 100mL mean PVR for patients with BT ≤ 10(5) CFU/mL versus 248 mL for patients with BT >10(5) CFU/mL. High PVR and BT were associated with complicated infections, concomitant bacteremia, and delayed apyrexia. Screening for patients with BT ≥ 10(6) CFU/mL is an easy way to identify patients at high risk for acute retention and voiding disorders.
authors.affiliation: Infectious Diseases Department, Rouen University Hospital, GRAM (EA2656), Rouen, France.
authors.forename: F
authors.initials: F
authors.lastname: Caron
authors.affiliation: Infectious Diseases Department, Rouen University Hospital, Rouen, France.
authors.forename: K
authors.initials: K
authors.lastname: Alexandre
authors.affiliation: Microbiology Department, Rouen University Hospital, GRAM (EA2656), Rouen, France.
authors.forename: M
authors.initials: M
authors.lastname: Pestel-Caron
authors.affiliation: Geriatrics Department, Rouen University Hospital, Rouen, France.
authors.forename: P
authors.initials: P
authors.lastname: Chassagne
authors.affiliation: Urology Department, Rouen University Hospital, Rouen, France.
authors.forename: P
authors.initials: P
authors.lastname: Grise
authors.affiliation: Infectious Diseases Department, Rouen University Hospital, GRAM (EA2656), Rouen, France. Electronic address: manuel.etienne@chu-rouen.fr.
authors.forename: M
authors.initials: M
authors.lastname: Etienne
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D058491:Bacterial Load; D004926:Escherichia coli / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014552:Urinary Tract Infections / Q000382:microbiology*; D014556:Urine / Q000382:microbiology*; D055815:Young Adult
keywords: Post-void residual urine; Urinary tract infection; Urine analysis