title: Unexpectedly Simple Synthesis of Benzazoles by tBuONa-Catalyzed Direct Aerobic Oxidative Cyclocondensation of o-Thio/Hydroxy/Aminoanilines with Alcohols under Air.
abstract: tBuONa-catalyzed direct aerobic oxidative cyclocondensation reactions of readily available alcohols and o-thio/hydroxy/aminoanilines under air have been developed and provide an efficient, practical, and green method for the synthesis of benzazoles. Mechanistic studies revealed that o-substituted anilines promote the initial aerobic alcohol-oxidation step, which explains the high reactivity and success of this unexpectedly simple and practical cyclocondensation method.
authors.affiliation: Zhejiang Key Laboratory of Carbon Materials, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, Zhejiang 325035 (P. R. China).
authors.forename: Xinkang
authors.initials: X
authors.lastname: Shi
authors.affiliation: Zhejiang Key Laboratory of Carbon Materials, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, Zhejiang 325035 (P. R. China).
authors.forename: Junmei
authors.initials: J
authors.lastname: Guo
authors.affiliation: Zhejiang Key Laboratory of Carbon Materials, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, Zhejiang 325035 (P. R. China).
authors.forename: Jianping
authors.initials: J
authors.lastname: Liu
authors.affiliation: Zhejiang Key Laboratory of Carbon Materials, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, Zhejiang 325035 (P. R. China).
authors.forename: Mingde
authors.initials: M
authors.lastname: Ye
authors.affiliation: Zhejiang Key Laboratory of Carbon Materials, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, Zhejiang 325035 (P. R. China). qing-xu@wzu.edu.cn.
authors.forename: Qing
authors.initials: Q
authors.lastname: Xu
keywords: aerobic oxidation; alcohols; cyclocondensation; green chemistry; nitrogen heterocycles