title: [Stimulation of the centromedian nucleus in refractory epilepsy associated to ring chromosome 20].
abstract: BACKGROUND
  Ring chromosome 20 syndrome is a rare genetic disorder, with a late diagnosis.
  
  
  METHODS
  A 43-year-old woman who had had refractory epilepsy since the age of six years, for which she was treated with deep brain stimulation of the centromedian nucleus, and also a ring chromosome 20.
  
  
  CONCLUSIONS
  From the findings of the study it can be concluded that deep brain stimulation of the centromedian nucleus is ineffective in patients with ring chromosome, but note must be taken of the importance of genetic characterisation for the management of refractory epilepsy.
authors.affiliation: Hospital Universitario de la Princesa, 28006 Madrid, Espana.
authors.forename: Alejandra
authors.initials: A
authors.lastname: Arévalo-Sáenz
authors.forename: Cristina V
authors.initials: CV
authors.lastname: Torres
authors.forename: Jesús
authors.initials: J
authors.lastname: Pastor
authors.forename: Concepción
authors.initials: C
authors.lastname: Alonso-Cerezo
authors.forename: Rafael G
authors.initials: RG
authors.lastname: Sola
mesh_terms: D000328:Adult; D046690:Deep Brain Stimulation; D000069279:Drug Resistant Epilepsy / Q000235:genetics / Q000628:therapy*; D005260:Female; D006801:Humans; D020646:Intralaminar Thalamic Nuclei; D012303:Ring Chromosomes