title: Central corneal thickness evaluation in healthy eyes with three different optical devices.
abstract: OBJECTIVE
  To compare corneal pachymetry values measured by three different optical devices: Orbscan II, Pentacam HR and Sirius in healthy eyes.
  
  
  METHODS
  The central corneal thickness (CCT) of 102 eyes of 102 healthy subjects (mean age of 33.09 ± 8.72 years and mean refractive defect -4.11 ± 4.74 D) was measured by three different physicians using Orbscan II, Pentacam HR and Sirius. The normality of the distribution was evaluated by with Kolmogorov-Smirnov test. The correlations between CCT obtained from each device and refractive defect and age were evaluated using the Pearson test. The differences were evaluated by the Student paired t-test using SPSS 18.0 (IBM Corp. Armonk, New York).
  
  
  RESULTS
  Orbscan II provided significant (p < 0.0001) lower CCT measurements then both Pentacam HR (-13.66 ± 16.53 μm) and Sirius (-15.18 ± 17.16 μm); Sirius showed values slightly higher than Oculus Pentacam HR (+1.52 ± 6.21 μm) that appeared to be statistically significant (p < 0.015).
  
  
  CONCLUSIONS
  The measurement of CCT by Sirius and Pentacam HR provides similar results. By contrast, the results obtained by Orbscan II are different from those obtained from both Sirius and Pentacam HR.
authors.affiliation: Dipartimento Multidisciplinare di Scienze Mediche, Chirurgiche e Odontoiatriche, Seconda Università di Napoli, Napoli, Italy; Centro Grandi Apparecchiature, Seconda Università di Napoli, Napoli, Italy. Electronic address: mic.lanza@gmail.com.
authors.forename: Michele
authors.initials: M
authors.lastname: Lanza
authors.affiliation: Dipartimento Multidisciplinare di Scienze Mediche, Chirurgiche e Odontoiatriche, Seconda Università di Napoli, Napoli, Italy.
authors.forename: Erica
authors.initials: E
authors.lastname: Paolillo
authors.affiliation: Dipartimento Multidisciplinare di Scienze Mediche, Chirurgiche e Odontoiatriche, Seconda Università di Napoli, Napoli, Italy.
authors.forename: Ugo Antonello
authors.initials: UA
authors.lastname: Gironi Carnevale
authors.affiliation: Dipartimento Multidisciplinare di Scienze Mediche, Chirurgiche e Odontoiatriche, Seconda Università di Napoli, Napoli, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Lanza
authors.affiliation: Centro Grandi Apparecchiature, Seconda Università di Napoli, Napoli, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Irregolare
authors.affiliation: Dipartimento Multidisciplinare di Scienze Mediche, Chirurgiche e Odontoiatriche, Seconda Università di Napoli, Napoli, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Mele
authors.affiliation: Dipartimento Multidisciplinare di Scienze Mediche, Chirurgiche e Odontoiatriche, Seconda Università di Napoli, Napoli, Italy.
authors.forename: Mario
authors.initials: M
authors.lastname: Bifani
mesh_terms: D000328:Adult; D003315:Cornea / Q000033:anatomy & histology*; D063171:Corneal Pachymetry / Q000295:instrumentation*; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055815:Young Adult
keywords: Central corneal thickness; Optical pachymetry; Orbscan II; Scheimpflug camera