title: Corticosteroid therapy in patients with non-arteritic anterior ischemic optic neuropathy.
abstract: Non-arteritic anterior ischemic optic neuropathy is one of the most common conditions affecting the optic nerve in the elderly. It may lead to severe visual loss. Typical symptoms are painless impairment of visual function accompanied by relative afferent pupillary defect, edema of the optic disc and visual field defects. Aim is to present 38 patients with nonarteritic anterior ischemic optic neuropathy who were treated with corticosteroid therapy. This prospective study involved 38 patients, 20 men and 18 women aged 60-75 years who were treated with corticosteroid therapy. The study included patients with visual acuity in the affected eye from 0.1 to 0.8 according to Snellen. Every patient underwent clinical examination, the Octopus 900 perimetry in G program, laboratory testing, while the compressive optic neuropathy was rule out with MSCT of the brain and orbits. The most common forms of visual field defect are altitudinal defect and diffuse depression. Corticosteroid therapy led to recovery in 65% of patient, in 30% of patients did not change, while the deterioration occurred in 5% of patients.
authors.forename: Tomislav
authors.initials: T
authors.lastname: Vidović
authors.forename: Branimir
authors.initials: B
authors.lastname: Cerovski
authors.forename: Sanja
authors.initials: S
authors.lastname: Perić
authors.forename: Rajko
authors.initials: R
authors.lastname: Kordić
authors.forename: Danijela
authors.initials: D
authors.lastname: Mrazovac
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D008875:Middle Aged; D009898:Optic Disk; D009900:Optic Nerve / Q000503:physiopathology*; D018917:Optic Neuropathy, Ischemic / Q000188:drug therapy*; D011446:Prospective Studies; D014792:Visual Acuity; D058609:Visual Field Tests
chemical_list: D000305:Adrenal Cortex Hormones; D008775:Methylprednisolone