title: Evaluation of the effectiveness of three physiotherapeutic treatments for subacromial impingement syndrome: a randomised clinical trial.
abstract: OBJECTIVE
  To determine whether dexketoprofen administered by phonophoresis or iontophoresis is more effective for the treatment of subacromial impingement syndrome (SIS) than conventional ultrasound therapy.
  
  
  METHODS
  Randomised clinical trial.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Ninety-nine participants with SIS without a complete tear of the rotator cuff were assigned at random to three intervention groups.
  Participants received ultrasound (n=32), phonophoresis with dexketoprofen (50mg/session) (n=33) or iontophoresis with dexketoprofen (50mg/session) (n=34). All participants completed 20 treatment sessions plus exercise therapy and cryotherapy.
  
  
  METHODS
  A visual analogue scale (VAS), the Constant-Murley Scale (CMS) and the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire were administered pre-treatment (baseline), post-treatment and 1 month post-treatment.
  
  
  RESULTS
  At baseline, there were no differences between the groups. Post-treatment, VAS score improved by -1.2 points and CMS score improved by 8.9 points in the ultrasound group compared with the iontophoresis group [95% confidence interval (CI) -0.2 to -2.2 and 95% CI 17.0 to 0.7, respectively]. CMS score improved by 7.1 points in the phonophoresis group compared with the iontophoresis group (95% CI 14.8 to -0.7). At 1 month post-treatment, no significant differences were detected between the groups. VAS, CMS and DASH scores of all groups improved post-treatment and at 1 month post-treatment.
  
  
  CONCLUSIONS
  Ultrasound, iontophoresis with dexketoprofen and phonophoresis with dexketoprofen can improve pain, shoulder function, and physical functioning and symptoms in the upper limb in patients with SIS without a complete tear of the rotator cuff. CLINICAL TRIALS.
  NCT01748188.
authors.affiliation: Sant Joan University Hospital, Reus, Spain; Faculty of Medicine and Health Sciences, Rovira i Virgili University, Reus, Spain. Electronic address: laura.perez@urv.cat.
authors.forename: L
authors.initials: L
authors.lastname: Pérez-Merino
authors.affiliation: Sant Joan University Hospital, Reus, Spain; Faculty of Medicine and Health Sciences, Rovira i Virgili University, Reus, Spain.
authors.forename: M C
authors.initials: MC
authors.lastname: Casajuana
authors.affiliation: Sant Joan University Hospital, Reus, Spain; Faculty of Medicine and Health Sciences, Rovira i Virgili University, Reus, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Bernal
authors.affiliation: Sant Joan University Hospital, Reus, Spain; Faculty of Medicine and Health Sciences, Rovira i Virgili University, Reus, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Faba
authors.affiliation: Sant Joan University Hospital, Reus, Spain; Faculty of Medicine and Health Sciences, Rovira i Virgili University, Reus, Spain.
authors.forename: A E
authors.initials: AE
authors.lastname: Astilleros
authors.affiliation: Sant Joan University Hospital, Reus, Spain; Faculty of Medicine and Health Sciences, Rovira i Virgili University, Reus, Spain.
authors.forename: R
authors.initials: R
authors.lastname: González
authors.affiliation: Faculty of Medicine and Health Sciences, Rovira i Virgili University, Reus, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Giralt
authors.affiliation: Faculty of Medicine and Health Sciences, Rovira i Virgili University, Reus, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Romeu
authors.affiliation: Faculty of Medicine and Health Sciences, Rovira i Virgili University, Reus, Spain.
authors.forename: M R
authors.initials: MR
authors.lastname: Nogués
mesh_terms: D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D017679:Cryotherapy / Q000379:methods; D005081:Exercise Therapy; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007478:Iontophoresis / Q000379:methods*; D007660:Ketoprofen / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D015612:Phonophoresis / Q000379:methods*; D016059:Range of Motion, Articular; D019534:Shoulder Impingement Syndrome / Q000628:therapy*; D020069:Shoulder Pain / Q000628:therapy; D016037:Single-Blind Method; D014325:Tromethamine / Q000008:administration & dosage / Q000627:therapeutic use*; D014464:Ultrasonic Therapy / Q000379:methods*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D014325:Tromethamine; D007660:Ketoprofen; C118296:dexketoprofen trometamol
keywords: Dexketoprofen; Iontophoresis; Phonophoresis; Subacromial impingement syndrome; Ultrasound therapy