title: Left Ventricular Assist Devices: A Rapidly Evolving Alternative to Transplant.
abstract: Left ventricular assist devices are becoming an increasingly prevalent therapy for patients with Stage D heart failure with reduced ejection fraction. Technological advances have improved the durability of these devices and have significantly lengthened survival in these patients. Quality of life is also improved, although adverse events related to device therapy remain common. Nevertheless, with the continuing organ donor shortage for cardiac transplantation, left ventricular assist devices are frequently serving as a substitute for transplant, particularly in the elderly patient.
authors.affiliation: Department of Medicine, Columbia University, New York, New York. Electronic address: dmm31@cumc.columbia.edu.
authors.forename: Donna
authors.initials: D
authors.lastname: Mancini
authors.affiliation: Department of Medicine, Columbia University, New York, New York.
authors.forename: Paolo C
authors.initials: PC
authors.lastname: Colombo
mesh_terms: D002986:Clinical Trials as Topic / Q000639:trends; D006333:Heart Failure / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D016027:Heart Transplantation / Q000639:trends*; D006352:Heart Ventricles / Q000601:surgery*; D006353:Heart-Assist Devices / Q000592:standards / Q000639:trends*; D006801:Humans; D011474:Prosthesis Design / Q000592:standards / Q000639:trends
keywords: heart assist devices; heart transplantation; heart failure