title: Outcomes of liver transplant with donors over 70 years of age.
abstract: Organ shortage has forced transplant teams to progressively expand the acceptance of marginal donors.
  
  
  METHODS
  We performed a comparative analysis of the post-transplant evolution depending on donor age (group I: less than 70 years old (n=474) vs. group II: 70 or more years old [n=105]) over a 10 year period (2002-2011).
  
  
  RESULTS
  Donors over 70 years old were similar to donors less than 70 years old in terms of ICU stay, gender, weight, laboratory results, and use of vasoactive drugs. However, the younger donor group presented with cardiac arrest more often (GI: 14 vs. GII: 3%, P=.005). There were no differences in initial poor function (GI: 6% vs. GII: 7,7%; P=.71), ICU stay (GI: 2.7±2 vs. GII: 3.3±3.8, P=.46), hospital stay (GI: 13.5±10 vs. GII: 15.5±11, P=.1), or hospital mortality (GI: 5.3 vs. GII: 5.8%, P=.66) between receptors of more or less than 70 year old grafts. After a median follow up of 32 months, no differences were found in the incidence of biliary tract complications (GI: 17 vs. GII: 20%, P=.4) or vascular complications (GI: 11 vs. GII: 9%, P=.69). The actuarial 5 year survival was similar for both study groups (GI: 70 vs. GII: 76%, P=.54).
  
  
  CONCLUSIONS
  In our experience, the use of grafts from donors older than 70 years, when other risk factors are avoided (cold ischemia, steatosis, sodium levels), does not worsen the results of liver transplantation on the short or long term.
authors.affiliation: Unidad de Cirugía Hepatobiliopancreática y Trasplante, Hospital Universitario de Bellvitge, Barcelona, España. Electronic address: kristel.mils@bellvitgehospital.cat.
authors.forename: Kristel
authors.initials: K
authors.lastname: Mils
authors.affiliation: Unidad de Cirugía Hepatobiliopancreática y Trasplante, Hospital Universitario de Bellvitge, Barcelona, España.
authors.forename: Laura
authors.initials: L
authors.lastname: Lladó
authors.affiliation: Unidad de Cirugía Hepatobiliopancreática y Trasplante, Hospital Universitario de Bellvitge, Barcelona, España.
authors.forename: Juan
authors.initials: J
authors.lastname: Fabregat
authors.affiliation: Unidad de Cirugía Hepatobiliopancreática y Trasplante, Hospital Universitario de Bellvitge, Barcelona, España.
authors.forename: Carme
authors.initials: C
authors.lastname: Baliellas
authors.affiliation: Unidad de Cirugía Hepatobiliopancreática y Trasplante, Hospital Universitario de Bellvitge, Barcelona, España.
authors.forename: Emilio
authors.initials: E
authors.lastname: Ramos
authors.affiliation: Unidad de Cirugía Hepatobiliopancreática y Trasplante, Hospital Universitario de Bellvitge, Barcelona, España.
authors.forename: Lluís
authors.initials: L
authors.lastname: Secanella
authors.affiliation: Unidad de Cirugía Hepatobiliopancreática y Trasplante, Hospital Universitario de Bellvitge, Barcelona, España.
authors.forename: Juli
authors.initials: J
authors.lastname: Busquets
authors.affiliation: Unidad de Cirugía Hepatobiliopancreática y Trasplante, Hospital Universitario de Bellvitge, Barcelona, España.
authors.forename: Núria
authors.initials: N
authors.lastname: Pelaez
mesh_terms: D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D014019:Tissue Donors; D016896:Treatment Outcome
keywords: Biliary complications; Complicaciones biliares; Criterios extendidos; Donor age; Edad de donantes; Extended-criteria; Liver transplantation; Patient survival; Supervivencia del paciente; Trasplante hepático