title: IMAGING DIAGNOSIS - UNILATERAL TRIGEMINAL NEURITIS MIMICKING PERIPHERAL NERVE SHEATH TUMOR IN A HORSE.
abstract: A 16-year old Warmblood gelding presented with a nonhealing corneal ulcer and absent corneal sensation in the left eye. A lesion affecting the maxillary and ophthalmic branches of the left trigeminal nerve was suspected. Magnetic resonance (MR) imaging identified marked thickening of the ophthalmic and maxillary branches of the left trigeminal nerve. The nerve was iso- to hypointense on T1-weighted and T2-weighted images with heterogeneous enhancement. A peripheral nerve sheath tumor was suspected, however granulomatous neuritis was histopathologically confirmed. These inflammatory changes can result in severe nerve enlargement and should be considered with MR findings suggestive of peripheral nerve sheath tumor.
authors.affiliation: Royal Veterinary College, University of London, Hawshead Lane, North Mymms, Hatfield, Herts, AL9 7TA, UK.
authors.forename: Elsa
authors.initials: E
authors.lastname: Beltran
authors.affiliation: Animal Health Trust, Lanwades Park, Newmarket, CB8 7UU, UK.
authors.forename: Rachael
authors.initials: R
authors.lastname: Grundon
authors.affiliation: Animal Health Trust, Lanwades Park, Newmarket, CB8 7UU, UK.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Stewart
authors.affiliation: Royal Veterinary College, University of London, Hawshead Lane, North Mymms, Hatfield, Herts, AL9 7TA, UK.
authors.forename: Marianna
authors.initials: M
authors.lastname: Biggi
authors.affiliation: Animal Health Trust, Lanwades Park, Newmarket, CB8 7UU, UK.
authors.forename: Andrew
authors.initials: A
authors.lastname: Holloway
authors.affiliation: Animal Health Trust, Lanwades Park, Newmarket, CB8 7UU, UK.
authors.forename: Courtenay
authors.initials: C
authors.lastname: Freeman
mesh_terms: D000818:Animals; D002701:Chloramphenicol / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006734:Horse Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D006736:Horses; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D018317:Nerve Sheath Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary*; D009443:Neuritis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary*; D009883:Ophthalmic Solutions / Q000627:therapeutic use; D016896:Treatment Outcome; D014276:Trigeminal Nerve / Q000473:pathology*
chemical_list: D009883:Ophthalmic Solutions; D002701:Chloramphenicol
keywords: MRI; horse; neuritis; trigeminal nerve