title: Macroscopic modelling of bioethanol production from potato peel wastes in batch cultures supplemented with inorganic nitrogen.
abstract: Inorganic nitrogen supplementation is commonly used to boost fermentation metabolism in yeast cultures. However, an excessive addition can induce an opposite effect. Hence, it is important to ensure that the ammonia supplemented to the culture leads to an improvement of the ethanol production while avoiding undesirable inhibition effects. To this end, a macroscopic model describing the influence of ammonia addition on Saccharomyces cerevisiae metabolism during bioethanol production from potato peel wastes has been developed. The model parameters are obtained by a simplified identification methodology in five steps. It is validated with experimental data and successfully predicts the dynamics of growth, substrate consumption (ammonia and fermentable sugar sources) and bioethanol production, even in cross validation. The model is used to determine the optimal quantity of supplemented ammonia required for maximizing bioethanol production from potato peel wastes in batch cultures.
authors.affiliation: 3BIO-BioControl, Université Libre de Bruxelles, Brussels, Belgium, arichell@ulb.ac.be.
authors.forename: A
authors.initials: A
authors.lastname: Richelle
authors.forename: I
authors.initials: I
authors.lastname: Ben Tahar
authors.forename: M
authors.initials: M
authors.lastname: Hassouna
authors.forename: Ph
authors.initials: P
authors.lastname: Bogaerts
mesh_terms: D000641:Ammonia / Q000378:metabolism; D019149:Bioreactors / Q000382:microbiology; D050260:Carbohydrate Metabolism / Q000502:physiology*; D049109:Cell Proliferation / Q000502:physiology; D003198:Computer Simulation; D000431:Ethanol / Q000302:isolation & purification / Q000378:metabolism*; D007220:Industrial Waste / Q000517:prevention & control; D007287:Inorganic Chemicals / Q000378:metabolism; D008954:Models, Biological; D009584:Nitrogen / Q000378:metabolism*; D012037:Refuse Disposal / Q000379:methods; D012441:Saccharomyces cerevisiae / Q000502:physiology*; D011198:Solanum tuberosum / Q000382:microbiology*
chemical_list: D007220:Industrial Waste; D007287:Inorganic Chemicals; D000431:Ethanol; D000641:Ammonia; D009584:Nitrogen