title: Attitudes Towards PrEP and Anticipated Condom Use Among Concordant HIV-Negative and HIV-Discordant Male Couples.
abstract: Since the July 2012 approval by the FDA of emtricitabine/ tenofovir disoproxil fumarate (Truvada) for use as pre-exposure prophylaxis (PrEP) against HIV, its feasibility and acceptability has been under study. HIV-discordant couples are likely targets for PrEP but little is known about how this new prevention tool impacts relationships. We examined, among gay male couples, the acceptability of individual and partner use of PrEP and intentions to use condoms with primary and outside partners in the context of PrEP use. Data are from two independent samples of couples recruited in the San Francisco bay area and New York City-a qualitative one (N=48 couples) between March and November, 2011, and a quantitative one (N=171 couples) between June, 2012 and May, 2013. Data were categorized by couple HIV status and general linear models; chi-square tests of independence were used to examine condom-use intentions with primary and outside partners, by sexual risk profile, and race. Almost half of the HIV-negative couples felt PrEP was a good HIV prevention strategy for themselves and their partner. Over half reported that they would not change their current condom use if they or their partner were taking PrEP. However, approximately 30% of HIV-negative couples reported that they would stop using condoms or use them less with primary and outside partners if they were on PrEP or if their partner was on PrEP. A large percentage of couples view PrEP positively. However, to ensure safety for both partners, future programing must consider those who intend not to use condoms while on PrEP.
authors.affiliation: 1 Center for Research and Education on Gender and Sexuality, San Francisco State University , San Francisco, California.
authors.forename: Colleen C
authors.initials: CC
authors.lastname: Hoff
authors.affiliation: 1 Center for Research and Education on Gender and Sexuality, San Francisco State University , San Francisco, California.|2 Center for AIDS Prevention Studies, University of California at San Francisco , San Francisco, California.
authors.forename: Deepalika
authors.initials: D
authors.lastname: Chakravarty
authors.affiliation: 1 Center for Research and Education on Gender and Sexuality, San Francisco State University , San Francisco, California.
authors.forename: Anja E
authors.initials: AE
authors.lastname: Bircher
authors.affiliation: 1 Center for Research and Education on Gender and Sexuality, San Francisco State University , San Francisco, California.
authors.forename: Chadwick K
authors.initials: CK
authors.lastname: Campbell
authors.affiliation: 3 Columbia University , Mailman School of Public Health, New York City, New York.
authors.forename: Kirk
authors.initials: K
authors.lastname: Grisham
authors.affiliation: 2 Center for AIDS Prevention Studies, University of California at San Francisco , San Francisco, California.
authors.forename: Torsten B
authors.initials: TB
authors.lastname: Neilands
authors.affiliation: 3 Columbia University , Mailman School of Public Health, New York City, New York.
authors.forename: Patrick A
authors.initials: PA
authors.lastname: Wilson
authors.affiliation: 4 Department of Social and Behavioral Sciences, University of California at San Francisco , San Francisco, California.
authors.forename: Shari
authors.initials: S
authors.lastname: Dworkin
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000008:administration & dosage; D017280:Condoms / Q000706:statistics & numerical data*; D005191:Family Characteristics; D015658:HIV Infections / Q000208:ethnology / Q000517:prevention & control* / Q000523:psychology; D018023:HIV Seronegativity; D006679:HIV Seropositivity; D007722:Health Knowledge, Attitudes, Practice; D006306:Health Surveys; D018451:Homosexuality, Male; D006801:Humans; D033182:Intention; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D009519:New York City; D010342:Patient Acceptance of Health Care / Q000208:ethnology / Q000523:psychology*; D065129:Pre-Exposure Prophylaxis; D036301:Qualitative Research; D012309:Risk-Taking; D012495:San Francisco; D012725:Sexual Behavior / Q000523:psychology / Q000706:statistics & numerical data; D012747:Sexual Partners / Q000523:psychology*
chemical_list: D019380:Anti-HIV Agents