title: Effect of addition of lycopene to calcium hydroxide and chlorhexidine as intracanal medicament on fracture resistance of radicular dentin at two different time intervals: An in vitro study.
abstract: BACKGROUND
  Long-term use of intracanal medicaments such as calcium hydroxide (CH) reduces the fracture resistance of dentin. The present study was undertaken to evaluate the fracture resistance of radicular dentin on long-term use of CH, chlorhexidine (CHX) with lycopene (LP).
  
  
  OBJECTIVE
  To compare the fracture resistance of radicular dentin when intracanal medicaments such as CH, CHX with LP were used for 1-week and 1-month time interval.
  
  
  METHODS
  Sixty single-rooted extracted human permanent premolars were collected, and complete instrumentation was done. Samples were divided into three groups based on intracanal medicament used.
  
  
  METHODS
  Group 1 - no medicament was placed (CON), group 2 - mixture of 1.5 g of CH and 1 ml of 2% CHX (CHCHX), group 3 - mixture of 1.5 g of CH, 1 ml of CHX and 1 ml of 5% LP solution (CHCHXLP). After storage period of each group for 1-week and 1-month, middle 8 mm root cylinder was sectioned and tested for fracture resistance.
  
  
  METHODS
  Results were analyzed using paired t-test.
  
  
  RESULTS
  At 1-month time interval, there was a statistically significant difference in fracture resistance between CHCHX and CHCHXLP groups.
  
  
  CONCLUSIONS
  Addition of LP has not decreased the fracture resistance of radicular dentin after 1-month.
authors.affiliation: Department of Conservative Dentistry and Endodontics, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: Koppolu
authors.initials: K
authors.lastname: Madhusudhana
authors.affiliation: Department of Conservative Dentistry and Endodontics, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: Kasamsetty
authors.initials: K
authors.lastname: Archanagupta
authors.affiliation: Department of Conservative Dentistry and Endodontics, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: Chinni
authors.initials: C
authors.lastname: Suneelkumar
authors.affiliation: Department of Conservative Dentistry and Endodontics, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: Anumula
authors.initials: A
authors.lastname: Lavanya
authors.affiliation: Department of Conservative Dentistry and Endodontics, Narayana Dental College and Hospital, Nellore, Andhra Pradesh, India.
authors.forename: Mandava
authors.initials: M
authors.lastname: Deepthi
keywords: Calcium hydroxide; fracture resistance; intracanal medicament; lycopene