title: The Role of Essential Fatty Acids in Anorexia Nervosa and Obesity.
abstract: The two basic questions in food intake study are what we eat, and how much do we eat. Most research is directed toward the control of how much is eaten. This is likely the result of the increased number of individuals with eating disorders in the Western world. Feeding behavior is highly complex, and is controlled by many psychological, physiological, biochemical, and immunological factors. The aim of this review is to clarify the involvement of fatty acids in eating disorders such as anorexia and binge eating disorder. The review will describe the modified fatty acid profile observed in individuals with anorexia or binge eating disorder, and discuss on what factors fatty acids can exert beneficial effects. In addition, the differences and similarities between anorexia and binge eating disorder will be discussed. We suggest that beneficial effects of essential fatty acids on both anorexia and binge eating disorder can be explained by the stabilizing effect of those fatty acids on the neuronal membrane fluidity index.
authors.affiliation: a Psychopharmacology Lab , Department of Psychology, Bar Ilan University , Ramat Gan , Israel.
authors.forename: Shlomo
authors.initials: S
authors.lastname: Yehuda
authors.affiliation: a Psychopharmacology Lab , Department of Psychology, Bar Ilan University , Ramat Gan , Israel.|b School of Criminology, University of Haifa , Mount Carmel , Israel.
authors.forename: Sharon
authors.initials: S
authors.lastname: Rabinovitz
mesh_terms: D000818:Animals; D000856:Anorexia Nervosa / Q000503:physiopathology; D056912:Binge-Eating Disorder / Q000503:physiopathology; D001812:Blood-Brain Barrier; D001921:Brain; D004032:Diet; D005228:Fatty Acids, Essential / Q000502:physiology*; D005247:Feeding Behavior; D001068:Feeding and Eating Disorders / Q000503:physiopathology; D006801:Humans; D008560:Membrane Fluidity; D009186:Myelin Sheath; D009474:Neurons / Q000502:physiology; D018377:Neurotransmitter Agents; D009765:Obesity / Q000503:physiopathology
chemical_list: D005228:Fatty Acids, Essential; D018377:Neurotransmitter Agents
keywords: Obesity; anorexia; cognition; cytokines; essential fatty acids; neurotransmitters; omega 3; sleep; stress