title: Using water-soluble C60fullerenes in anticancer therapy.
abstract: Growth experiments of transplanted malignant tumors in the presence of water-soluble C60fullerenes were performed on groups of mice. It was found that C60fullerenes efficiently inhibit the growth of transplanted malignant tumors. This behavior can be explained through their high antioxidant activity and the blocking of the specific cell receptors (for example, endothelial growth factor). The findings demonstrate the possibility of using C60fullerenes in anticancer therapy.
authors.affiliation: Institute of Biology, Kyiv National Taras Shevchenko University, Volodymyrska Str., 64, 01601 Kyiv, Ukraine.
authors.forename: S V
authors.initials: SV
authors.lastname: Prylutska
authors.affiliation: R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of NAS of Ukraine, Vasylkivska Str. 45, 03022 Kyiv, Ukraine.
authors.forename: A P
authors.initials: AP
authors.lastname: Burlaka
authors.affiliation: State Institute of Gerontology of AMS of Ukraine, Vyshgorodska Str., 67, 04114 Kyiv, Ukraine.
authors.forename: P P
authors.initials: PP
authors.lastname: Klymenko
authors.affiliation: Institute of Biology, Kyiv National Taras Shevchenko University, Volodymyrska Str., 64, 01601 Kyiv, Ukraine.
authors.forename: I I
authors.initials: II
authors.lastname: Grynyuk
authors.affiliation: Institute of Biology, Kyiv National Taras Shevchenko University, Volodymyrska Str., 64, 01601 Kyiv, Ukraine.
authors.forename: Yu I
authors.initials: YI
authors.lastname: Prylutskyy
authors.affiliation: Department of Chemistry, Technical University of Ilmenau, Weimarer Str. 25, 098693 Ilmenau, Germany.
authors.forename: Ch
authors.initials: C
authors.lastname: Schütze
authors.affiliation: Department of Chemistry, Technical University of Ilmenau, Weimarer Str. 25, 098693 Ilmenau, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Ritter
keywords: C60 fullerenes; Histological data; Increasing of animal life; Lewis lung carcinoma; Metastasis inhibition index; Mice line C57Bl/6J; Survival of animals; Tumor growth inhibition