title: Neuropathic Pain Components in Patients with Lumbar Spinal Stenosis.
abstract: OBJECTIVE
  To determine the prevalence and characteristics of neuropathic pain (NP) in patients with lumbar spinal stenosis (LSS) according to subgroup analysis of symptoms.
  
  
  METHODS
  We prospectively enrolled subjects with LSS (n=86) who were scheduled to undergo spinal surgery. The patients were divided into two groups according to a chief complaint of radicular pain or neurogenic claudication. We measured patient's pain score using the visual analog scale (VAS), Oswestry Disability Index (ODI) and Leads Assessment of Neuropathic Symptoms and Signs (LANSS). According to LANSS value, the prevalence of NP component pain in patients with LSS was assessed. Statistical analysis was performed to find the relationship between LANSS scores and the other scores.
  
  
  RESULTS
  From our sample of 86 patients, 31 (36.0%) had a NP component, with 24 (63.4%) in the radicular pain group having NP. However, only seven patients (15.6%) in the neurogenic claudication group had NP. The LANSS pain score was not significantly correlated with VAS scores for back pain, but did correlate with VAS scores for leg pain (R=0.73, p<0.001) and with ODI back pain scores (R=0.54, p<0.01).
  
  
  CONCLUSIONS
  One-third of the patients with LSS had a NP component. The presence of radicular pain correlated strongly with NP. The severity of leg pain and ODI score were also closely related to a NP component. This data may prove useful to understanding the pain characteristics of LSS and in better designing clinical trials for NP treatment in patients with LSS.
authors.affiliation: Department of Orthopedic Surgery, Korea University College of Medicine, Seoul, Korea. drspine90@gmail.com.
authors.forename: Si Young
authors.initials: SY
authors.lastname: Park
authors.affiliation: Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, USA.
authors.forename: Howard S
authors.initials: HS
authors.lastname: An
authors.affiliation: Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Seong Hwan
authors.initials: SH
authors.lastname: Moon
authors.affiliation: Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Hwan Mo
authors.initials: HM
authors.lastname: Lee
authors.affiliation: Department of Orthopedic Surgery, Korea University College of Medicine, Seoul, Korea.
authors.forename: Seung Woo
authors.initials: SW
authors.lastname: Suh
authors.affiliation: Department of Orthopedic Surgery, The Second Hospital of Xiangya, Central South University, Changsha, Hunan, P.R. China.
authors.forename: Ding
authors.initials: D
authors.lastname: Chen
authors.affiliation: Department of Orthopedic Surgery, Korea University College of Medicine, Seoul, Korea.
authors.forename: Jin Ho
authors.initials: JH
authors.lastname: Jeon
mesh_terms: D000328:Adult; D000368:Aged; D001416:Back Pain; D019299:Decompression, Surgical; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000150:complications* / Q000453:epidemiology; D017063:Outcome Assessment, Health Care; D010147:Pain Measurement / Q000379:methods*; D015995:Prevalence; D011446:Prospective Studies; D056910:Republic of Korea / Q000453:epidemiology; D012720:Severity of Illness Index; D013130:Spinal Stenosis / Q000453:epidemiology / Q000601:surgery*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
keywords: Leads Assessment of Neuropathic Symptoms and Signs; Neuropathic pain; Oswestry Disability Index; spinal stenosis; visual analog scale