title: Stress defense mechanisms of NADPH-dependent thioredoxin reductases (NTRs) in plants.
abstract: Plants establish highly and systemically organized stress defense mechanisms against unfavorable living conditions. To interpret these environmental stimuli, plants possess communication tools, referred as secondary messengers, such as Ca(2+) signature and reactive oxygen species (ROS) wave. Maintenance of ROS is an important event for whole lifespan of plants, however, in special cases, toxic ROS molecules are largely accumulated under excess stresses and diverse enzymes played as ROS scavengers. Arabidopsis and rice contain 3 NADPH-dependent thioredoxin reductases (NTRs) which transfer reducing power to Thioredoxin/Peroxiredoxin (Trx/Prx) system for scavenging ROS. However, due to functional redundancy between cytosolic and mitochondrial NTRs (NTRA and NTRB, respectively), their functional involvements under stress conditions have not been well characterized. Recently, we reported that cytosolic NTRA confers the stress tolerance against oxidative and drought stresses via regulation of ROS amounts using NTRA-overexpressing plants. With these findings, mitochondrial NTRB needs to be further elucidated.
authors.affiliation: a Division of Applied Life Science (BK21Plus); Institute of Agriculture & Life Science; Gyeongsang National University ; Jinju , Republic of Korea.
authors.forename: Joon-Yung
authors.initials: JY
authors.lastname: Cha
authors.forename: Dhirendra Nath
authors.initials: DN
authors.lastname: Barman
authors.forename: Min Gab
authors.initials: MG
authors.lastname: Kim
authors.forename: Woe-Yeon
authors.initials: WY
authors.lastname: Kim
mesh_terms: D000222:Adaptation, Physiological; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000201:enzymology*; D013312:Stress, Physiological; D013880:Thioredoxin-Disulfide Reductase / Q000378:metabolism*
chemical_list: D010940:Plant Proteins; D013880:Thioredoxin-Disulfide Reductase
keywords: NADPH-dependent thioredoxin reductase (NTR); Thioredoxin; reactive oxygen species (ROS); stress response