title: Nanostructure formation-induced fluorescence turn-on for selectively detecting protein thiols in solutions, bacteria and live cells.
abstract: We report the design and synthesis of a light-up probe of DBT-2(EEGK-maleimide), which can serve as a unique probe for selectively detecting protein thiols in various environments, including aqueous solutions, bacteria and live cells.
authors.affiliation: Cardiovascular Medicine Department of Guangzhou Panyu Central Hospital, 8 Fuyudonglu Qiaonanjie Panyu District, Guangzhou, P. R. China.
authors.forename: Guoqin
authors.initials: G
authors.lastname: Chen
authors.forename: Yongquan
authors.initials: Y
authors.lastname: Hua
authors.forename: Caiwen
authors.initials: C
authors.lastname: Ou
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Zhang
authors.forename: Duo
authors.initials: D
authors.lastname: Mao
authors.forename: Zhimou
authors.initials: Z
authors.lastname: Yang
authors.forename: Dan
authors.initials: D
authors.lastname: Ding
authors.forename: Minsheng
authors.initials: M
authors.lastname: Chen
mesh_terms: D001419:Bacteria / Q000378:metabolism*; D002460:Cell Line; D005456:Fluorescent Dyes / Q000737:chemistry*; D061307:Human Umbilical Vein Endothelial Cells; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D008301:Maleimides / Q000737:chemistry; D018613:Microscopy, Confocal; D049329:Nanostructures / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D012996:Solutions / Q000737:chemistry; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D014466:Ultraviolet Rays
chemical_list: D005456:Fluorescent Dyes; D047908:Intracellular Signaling Peptides and Proteins; D008301:Maleimides; D010455:Peptides; D011506:Proteins; D012996:Solutions; D013438:Sulfhydryl Compounds; C421249:TAX1BP3 protein, human; C043592:maleimide