title: Synthesis of benzimidazoles via iridium-catalyzed acceptorless dehydrogenative coupling.
abstract: Iridium-catalyzed acceptorless dehydrogenative coupling of tertiary amines and arylamines has been developed. A number of benzimidazoles were prepared in good yields. An iridium-mediated C-H activation mechanism is suggested. This finding represents a novel strategy for the synthesis of benzimidazoles.
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. yanming@mail.sysu.edu.cn.
authors.forename: Xiang
authors.initials: X
authors.lastname: Sun
authors.forename: Xiao-Hui
authors.initials: XH
authors.lastname: Lv
authors.forename: Lin-Miao
authors.initials: LM
authors.lastname: Ye
authors.forename: Yu
authors.initials: Y
authors.lastname: Hu
authors.forename: Yan-Yan
authors.initials: YY
authors.lastname: Chen
authors.forename: Xue-Jing
authors.initials: XJ
authors.lastname: Zhang
authors.forename: Ming
authors.initials: M
authors.lastname: Yan
mesh_terms: D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D006865:Hydrogenation; D007495:Iridium / Q000737:chemistry*; D004364:Pharmaceutical Preparations / Q000737:chemistry; D066244:Proton Magnetic Resonance Spectroscopy
chemical_list: D001562:Benzimidazoles; D004364:Pharmaceutical Preparations; D007495:Iridium