title: Special delivery: microparticles convey heme.
abstract: In this issue of Blood, Camus et al describe how microparticles derived from sickle erythrocytes can deliver heme to vascular endothelial cells, leading to their activation and injury, and promote vasoocclusion in sickle cell disease (SCD).
authors.affiliation: UNIVERSITY OF MINNESOTA.
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Vercellotti
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications*; D000818:Animals; D055252:Cell-Derived Microparticles / Q000473:pathology*; D042783:Endothelial Cells / Q000473:pathology*; D006418:Heme / Q000378:metabolism*; D006801:Humans; D008297:Male; D014652:Vascular Diseases / Q000209:etiology*
chemical_list: D006418:Heme