title: Use of Elemental Sulfur or Selenium in a Novel One-Pot Copper-Catalyzed Tandem Cyclization of Functionalized Ynamides Leading to Benzosultams.
abstract: A novel and efficient [Cu]-catalyzed one-pot regio- and stereospecific synthesis of benzo[1,4,2]dithiazine 1,1-dioxides and benzo[1,4,2]thiaselenazine 1,1-dioxides by cyclization of functionalized ynamides with elemental sulfur/selenium has been developed. Its generality is elegantly illustrated by extension to benzodithiazepines and benzothiaselenazepines. Involvement of water in the reaction is demonstrated by the incorporation of (2)D at the olefinic site by using D2O in place of water. Selective oxidation at sulfur in benzo[1,4,2]dithiazine 1,1-dioxide by using mCPBA as the oxidizing agent is also described.
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad-500046, Telangana, India.
authors.forename: Alla
authors.initials: A
authors.lastname: Siva Reddy
authors.affiliation: School of Chemistry, University of Hyderabad, Hyderabad-500046, Telangana, India.
authors.forename: K C
authors.initials: KC
authors.lastname: Kumara Swamy