title: Barriers to Clinical Trial Participation: Comparing Perceptions and Knowledge of African American and White South Carolinians.
abstract: Analyzing data from a survey of African American and White residents in South Carolina, this study attempts to understand how to better promote clinical trial participation specifically within the African American population. To explore why participation is lower in the African American population, the authors examined two sets of potential barriers: structural/procedural (limited accessibility, lack of awareness, doctors not discussing clinical trial options, lack of health insurance) and cognitive/psychological (lack of subjective and factual knowledge, misperceptions, distrust, fear, perceived risk). Findings revealed that African Americans were significantly less willing than Whites to participate in a clinical trial. African Americans also had lower subjective and factual knowledge about clinical trials and perceived greater risk involved in participating in a clinical trial. The authors found that lack of subjective knowledge and perceived risk were significant predictors of African Americans' willingness to participate in a clinical trial. Implications of the findings are discussed in detail.
authors.affiliation: a School of Journalism and Mass Communications , University of South Carolina , Columbia , South Carolina , USA.
authors.forename: Sei-Hill
authors.initials: SH
authors.lastname: Kim
authors.forename: Andrea
authors.initials: A
authors.lastname: Tanner
authors.forename: Daniela B
authors.initials: DB
authors.lastname: Friedman
authors.forename: Caroline
authors.initials: C
authors.lastname: Foster
authors.forename: Caroline
authors.initials: C
authors.lastname: Bergeron
mesh_terms: D000328:Adult; D001741:Black or African American / Q000523:psychology* / Q000706:statistics & numerical data; D000368:Aged; D002986:Clinical Trials as Topic; D005260:Female; D007722:Health Knowledge, Attitudes, Practice / Q000208:ethnology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care / Q000208:ethnology* / Q000706:statistics & numerical data; D018570:Risk Assessment; D012959:Socioeconomic Factors; D013022:South Carolina; D044465:White People / Q000523:psychology* / Q000706:statistics & numerical data