title: [Allogeneic parathyroid: 2-year follow-up].
abstract: BACKGROUND
  Hypoparathyroidism is one of the most frequent complications of neck surgery. The treatment is currently medical; however this involves several complications secondary to high doses of calcium and vitamin D, thus making parathyroid allotransplantation a good management option.
  
  
  METHODS
  Patients with hypoparathyroidism were selected in the April-December period of 2011 in the general surgical clinic. They were between 16 and 65 years, and ingested high doses of calcium. The donors were patients with primary and secondary hyperparathyroidism, and the transplants were performed in relation to blood group and human leucocyte antigen.
  
  
  RESULTS
  Five parathyroid allografts were performed. All the patients had iatrogenic hypoparathyroidism, all women with a mean age of 49.8 years. The graft was implanted under local anaesthesia in the non-dominant forearm. Four of the patients are so far considered functional due to the increase in paratohormone, and demonstrating its function by scintigraphy with sestamibi. One of the patients showed no increase in paratohormone or imaging studies that demonstrate its functionality. After a two year follow up the graft remains functional but with with oral calcium intake at a lower dose than before transplantation. None of the patients had immunosuppression side effects.
  
  
  CONCLUSIONS
  In this study, allogeneic unrelated living parathyroid transplant with an immunosuppressive regimen of six months has proven to be a safe alternative treatment to improve quality of life by decreasing the excessive calcium intake and improving physical activity with adequate graft survival at 24 months follow up.
authors.affiliation: Unidad Médica de Alta Especialidad, Departamento de Cirugía General, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Hermosillo-Sandoval
authors.affiliation: Unidad Médica de Alta Especialidad, Departamento de Cirugía General, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
authors.forename: Karla Lisseth
authors.initials: KL
authors.lastname: Leonher-Ruezga
authors.affiliation: Unidad Médica de Alta Especialidad, Departamento de Cirugía General, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
authors.forename: José Alfredo
authors.initials: JA
authors.lastname: Jiménez-Gómez
authors.affiliation: Unidad de Investigación en Epidemiología Clínica, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
authors.forename: Clotilde
authors.initials: C
authors.lastname: Fuentes-Orozco
authors.affiliation: Unidad de Investigación en Epidemiología Clínica, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
authors.forename: Alejandro
authors.initials: A
authors.lastname: González-Ojeda
authors.affiliation: Unidad Médica de Alta Especialidad, Departamento de Cirugía General, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México. Electronic address: luisricardo.rg@hotmail.com.
authors.forename: Luis Ricardo
authors.initials: LR
authors.lastname: Ramírez-González
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D064591:Allografts; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007011:Hypoparathyroidism / Q000601:surgery*; D008875:Middle Aged; D010280:Parathyroid Glands / Q000637:transplantation*; D011183:Postoperative Complications / Q000601:surgery*; D013997:Time Factors; D055815:Young Adult
keywords: Allotrasplant; Alotrasplante; Hipocalcemia; Hipoparatiroidismo; Hypocalcaemia; Hypoparathyroidism; Parathyroid; Paratiroides