title: [Evolution of oxidant-antioxidant homeostasis in patients with eczema treated using different methods].
abstract: to study the evolution of the oxidant-antioxidant homeostasis indices in patients with eczema using various methods of treating dermatosis. The study involved 63 patients with eczema (34 - males, 28 - females), aged 18-67 years, who were determined indices of pro- and antioxidant systems of blood. Patients with eczema were divided into 3 groups that were prescribed different treatments: the first comparative group (21 patients) - received a standard therapy; the second comparative group (20 patients) - had a standard therapy and additionally an antioxidant preparation "Mexidol", the third (basic group) - 22 patients, who were prescribed a complex therapy with a combination of two drugs with antioxidant effect: "Mexidol" and "Galavit." It was established that multimodality therapy for eczema while using two drugs with antioxidant action ("Mexidol", "Galavit") contributes to the most significant positive dynamics and normalization of the studied parameters of oxidant-antioxidant homeostasis of patients compared to a standard therapy of dermatosis or its combination with antioxidant preparation "Mexidol".
authors.affiliation: Bukovinian State Medical University, Chernovtsy, Ukraine.
authors.forename: N
authors.initials: N
authors.lastname: Stepan
authors.affiliation: Bukovinian State Medical University, Chernovtsy, Ukraine.
authors.forename: O
authors.initials: O
authors.lastname: Denysenko
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000378:metabolism*; D004485:Eczema / Q000097:blood* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006706:Homeostasis / Q000187:drug effects*; D006801:Humans; D008165:Luminol / Q000008:administration & dosage / Q000031:analogs & derivatives; D008297:Male; D008875:Middle Aged; D016877:Oxidants / Q000097:blood*; D010847:Picolines / Q000008:administration & dosage
chemical_list: D000975:Antioxidants; D016877:Oxidants; D010847:Picolines; C070020:emoxypine succinate; D008165:Luminol; C511308:sodium luminolate