title: Structure and Absolute Configuration of Diterpenoids from Hymenaea stigonocarpa.
abstract: Chemical investigations of the ethanolic extracts from the flowers and leaves of Hymenaea stigonocarpa Mart. ex Hayne afforded one new ent-halimane diterpenoid, 18-hydroxy-ent-halima-1(10),13-(E)-dien-15-oic acid (1), together with five known compounds (2-6). The structural elucidation was performed by means of NMR (COSY, HSQC, HMBC, and NOESY) and MS analyses. Complete (1)H and (13)C NMR data assignments are also reported for labd-13-en-8β-ol-15-oic (2) and labd-7,13-dien-15-oic (3) acids. The absolute configurations of 1 and 2 were established by comparison of experimental and calculated Raman optical activity spectra.
authors.affiliation: †Unidade Acadêmica Especial de Física e Química, Universidade Federal de Goiás, Avenida Dr. Lamartine Pinto de Avelar, 1120, 75704-020, Catalão, GO, Brazil.
authors.forename: Afif F
authors.initials: AF
authors.lastname: Monteiro
authors.affiliation: ‡Departamento de Química Orgânica, Universidade Estadual Paulista "Júlio de Mesquita Filho", Rua Prof. Francisco Degni, 55, 14800-060, Araraquara, SP, Brazil.
authors.forename: João M
authors.initials: JM
authors.lastname: Batista
authors.affiliation: †Unidade Acadêmica Especial de Física e Química, Universidade Federal de Goiás, Avenida Dr. Lamartine Pinto de Avelar, 1120, 75704-020, Catalão, GO, Brazil.
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Machado
authors.affiliation: †Unidade Acadêmica Especial de Física e Química, Universidade Federal de Goiás, Avenida Dr. Lamartine Pinto de Avelar, 1120, 75704-020, Catalão, GO, Brazil.
authors.forename: Richele P
authors.initials: RP
authors.lastname: Severino
authors.affiliation: §Manchester Institute of Biotechnology and Faculty of Life Sciences, University of Manchester, 131 Princess Street, M1 7DN, Manchester, United Kingdom.
authors.forename: Ewan W
authors.initials: EW
authors.lastname: Blanch
authors.affiliation: ‡Departamento de Química Orgânica, Universidade Estadual Paulista "Júlio de Mesquita Filho", Rua Prof. Francisco Degni, 55, 14800-060, Araraquara, SP, Brazil.
authors.forename: Vanderlan S
authors.initials: VS
authors.lastname: Bolzani
authors.affiliation: ⊥Departamento de Química, Universidade Federal de São Carlos, Rod. Washington Luis, km 235, 13565-905, São Carlos, SP, Brazil.
authors.forename: Paulo C
authors.initials: PC
authors.lastname: Vieira
authors.affiliation: †Unidade Acadêmica Especial de Física e Química, Universidade Federal de Goiás, Avenida Dr. Lamartine Pinto de Avelar, 1120, 75704-020, Catalão, GO, Brazil.
authors.forename: Vanessa G P
authors.initials: VG
authors.lastname: Severino
mesh_terms: D001938:Brazil; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D035264:Flowers / Q000737:chemistry; D052597:Hymenaea / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry
chemical_list: C000601163:18-hydroxy-ent-halima-1(10),13-(E)-dien-15-oic acid; D004224:Diterpenes