title: LymphomiRs: microRNAs with regulatory roles in lymphomas.
abstract: OBJECTIVE
  This review provides current knowledge on the role of microRNAs (miRNAs) in lymphoma with an emphasis on mature B-cell lymphoma.
  
  
  RESULTS
  Although miRNAs were previously used to stratify lymphoma classification, prognosis, or treatment response, recent publications portray this class of small noncoding RNAs as critical players in the lymphomagenesis process. Although functional studies provide ample evidence for their role as lymphoma drivers or suppressors, genetic studies providing the underlying mechanisms for these phenotypes are still lacking. As more whole-genome sequencing of lymphoma cases become available, this gap may be soon filled.
  
  
  CONCLUSIONS
  Current findings highlight the potential role of miRNAs molecules as important factors in lymphomagenesis.
authors.affiliation: aDivision of Hematology-Oncology, Department of Medicine bDepartment of Molecular and Cellular Pharmacology, Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, USA.
authors.forename: Goldi A
authors.initials: GA
authors.lastname: Kozloski
authors.forename: Izidore S
authors.initials: IS
authors.lastname: Lossos
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000378:metabolism / Q000473:pathology; D063646:Carcinogenesis / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D003564:Cytidine Deaminase / Q000235:genetics / Q000378:metabolism; D004195:Disease Models, Animal; D015972:Gene Expression Regulation, Neoplastic; D018858:Germinal Center / Q000378:metabolism / Q000473:pathology; D006801:Humans; D016393:Lymphoma, B-Cell / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D051379:Mice; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism; D015398:Signal Transduction; D000098830:AICDA (Activation-Induced Cytidine Deaminase)
chemical_list: D035683:MicroRNAs; D000098830:AICDA (Activation-Induced Cytidine Deaminase); D003564:Cytidine Deaminase