title: [Viral hepatitis delta. Is there the delta infection problem in the Russian Federation?].
abstract: Hepatitis delta (HD) is characterized by rapid progression to fibrosis, and development of hepatocellular carcinoma, and a high mortality rate. The article presents data on the epidemiology, diagnosis, treatment of HD. The views of the epidemiological, clinical and virological characteristics of HD-infection among population of the Russian Federation (RF) are limited due to absence of official HD registration and detection of antibodies to the HD virus (anti-HDV) in HBsAg-positive individuals. However, some areas of the country are characterized by a high HDV circulation (Republic Tyva (RT) - 46,5%, Republic Sakha (Yakutia) - 12,5%) according to our studies conducted in 6 regions of Russia. Clinical-epidemiological situation of HDV infection in RT can be considered as a model to create a program of optimize diagnosis, prevention and treatment of HDV-infection in the Russian Federation.
authors.forename: T V
authors.initials: TV
authors.lastname: Kozhanova
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Il'chenko
authors.forename: M I
authors.initials: MI
authors.lastname: Mikhaĭlov
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D000998:Antiviral Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004353:Drug Evaluation, Preclinical; D003699:Hepatitis D / Q000453:epidemiology* / Q000628:therapy / Q000821:virology; D003698:Hepatitis Delta Virus / Q000187:drug effects / Q000276:immunology*; D006801:Humans; D016031:Liver Transplantation; D012367:RNA, Viral / Q000097:blood; D012426:Russia / Q000453:epidemiology; D014779:Virus Replication / Q000187:drug effects
chemical_list: D000914:Antibodies, Viral; D000998:Antiviral Agents; D012367:RNA, Viral