title: Identification of the somatosensory parietal ventral area and overlap of the somatosensory and auditory cortices in mice.
abstract: This study aimed to identify the parietal ventral (PV) area of the somatosensory cortex in mice and to determine whether auditory cortex and somatosensory cortex overlap. Using high resolution, voltage-sensitive dye-based imaging, we identified the PV area, which exhibited strong responses to stimulation of distal body parts but weak responses to stimulation of proximal and facial body parts. We further demonstrated a substantial overlap between the auditory and non-primary somatosensory areas, including the PV area. We found statistically significant non-additive integration of auditory and somatosensory inputs in the overlapping region, suggesting convergence of the two input streams at the cellular level. We have thus delineated the PV area in mice for the first time, and have shown that it is a likely site for the integration of auditory and somatic inputs.
authors.affiliation: Department of Sensory and Cognitive Physiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
authors.forename: Masataka
authors.initials: M
authors.lastname: Nishimura
authors.affiliation: Department of Sensory and Cognitive Physiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Sawatari
authors.affiliation: Department of Sensory and Cognitive Physiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Takemoto
authors.affiliation: Department of Sensory and Cognitive Physiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan; HIGO Program, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan. Electronic address: song@kumamoto-u.ac.jp.
authors.forename: Wen-Jie
authors.initials: WJ
authors.lastname: Song
mesh_terms: D000818:Animals; D001303:Auditory Cortex / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods; D007091:Image Processing, Computer-Assisted; D008810:Mice, Inbred C57BL; D023421:Models, Animal; D010296:Parietal Lobe / Q000502:physiology*; D013003:Somatosensory Cortex / Q000502:physiology*
keywords: Auditory cortex; Mouse; Multimodal integration; Optical imaging; Somatosensory cortex