title: Identification of safranal as the main allelochemical from saffron (Crocus sativus).
abstract: Dried parts of 75 medicinal plant species collected from different regions in Iran were assayed by the Dish Pack Method for volatile allelopathic activity, using Lactuca sativa (lettuce) as the test plant. The highest (60%) inhibition was observed for saffron (stigma of Crocus sativus), followed by Dracocephalum kotschyi, Solanum nigrum and Artemisia aucheri. Safranal was identified as the main chemical by Headspace Gas Chromatography-Mass Spectrometry (HS- GC-MS) analyses of saffron. Moreover, the EC50 of safranal was evaluated as 1.2 μg/L (ppb). This is the first report on allelopathic activity of safranal as a bioactive compound identified from saffron.
authors.forename: Hossein
authors.initials: H
authors.lastname: Mardani
authors.forename: Takayuki
authors.initials: T
authors.lastname: Sekine
authors.forename: Majid
authors.initials: M
authors.lastname: Azizi
authors.forename: Maryia
authors.initials: M
authors.lastname: Mishyna
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Fujii
mesh_terms: D027622:Crocus / Q000737:chemistry*; D053138:Cyclohexenes / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology*; D035264:Flowers / Q000737:chemistry; D018545:Lactuca / Q000187:drug effects / Q000254:growth & development; D010675:Pheromones / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology*; D013729:Terpenes / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D053138:Cyclohexenes; D010675:Pheromones; D010936:Plant Extracts; D013729:Terpenes; C087963:safranal