title: A Pilot Study of a Cognitive-Behavioral Treatment for Anxiety and Depression in Patients With Parkinson Disease.
abstract: Anxiety and depression often remain unrecognized or inadequately treated in patients with Parkinson disease (PD). Cognitive-behavioral therapy (CBT) is effective, but limited evidence supports its use for anxiety and depression in patients with PD. Sixteen patients with PD having significant anxiety and/or depressive symptoms were assigned to CBT or enhanced usual care. Assessments occurred at baseline, posttreatment, and 1-month follow-up. The CBT intervention included tools for anxiety, depression, and healthy living with PD symptoms. Individual sessions were delivered by telephone or in person, based on patient preference. Treatment was feasible with participants choosing 67% of sessions by telephone and 80% completed treatment. The between-group effect sizes for change scores from baseline to posttreatment and baseline to 1-month follow-up were large (posttreatment: d = 1.49 for depression and 1.44 for anxiety; 1-month follow-up: d = .73 for depression and 1.24 for anxiety), although only the posttreatment effect size for depression was significant. This pilot CBT program is feasible for treatment of anxiety and depression in patients with PD.
authors.affiliation: Houston VA Health Services Research and Development (HSR&D) Center for Innovations in Quality, Effectiveness and Safety, Houston, TX, USA Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA Baylor College of Medicine, Houston, TX, USA jcalleo@bcm.edu.
authors.forename: Jessica S
authors.initials: JS
authors.lastname: Calleo
authors.affiliation: Houston VA Health Services Research and Development (HSR&D) Center for Innovations in Quality, Effectiveness and Safety, Houston, TX, USA Baylor College of Medicine, Houston, TX, USA.
authors.forename: Amber B
authors.initials: AB
authors.lastname: Amspoker
authors.affiliation: Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA Baylor College of Medicine, Houston, TX, USA.
authors.forename: Aliya I
authors.initials: AI
authors.lastname: Sarwar
authors.affiliation: Houston VA Health Services Research and Development (HSR&D) Center for Innovations in Quality, Effectiveness and Safety, Houston, TX, USA Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA Baylor College of Medicine, Houston, TX, USA VA South Central Mental Illness Research, Education and Clinical Center.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Kunik
authors.affiliation: Baylor College of Medicine, Houston, TX, USA.
authors.forename: Joseph
authors.initials: J
authors.lastname: Jankovic
authors.affiliation: Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA Baylor College of Medicine, Houston, TX, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Marsh
authors.affiliation: Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA Baylor College of Medicine, Houston, TX, USA.
authors.forename: Michele
authors.initials: M
authors.lastname: York
authors.affiliation: Houston VA Health Services Research and Development (HSR&D) Center for Innovations in Quality, Effectiveness and Safety, Houston, TX, USA Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, USA Baylor College of Medicine, Houston, TX, USA VA South Central Mental Illness Research, Education and Clinical Center.
authors.forename: Melinda A
authors.initials: MA
authors.lastname: Stanley
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D003071:Cognition; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003863:Depression / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000523:psychology*; D010865:Pilot Projects; D015397:Program Evaluation; D011569:Psychiatric Status Rating Scales; D011795:Surveys and Questionnaires; D017216:Telemedicine; D013689:Telephone; D016896:Treatment Outcome
keywords: Parkinson disease; anxiety; cognitive–behavioral therapy; depression