title: Paravalvular Leak Leading to Severe Aortic Valve Regurgitation after TAVI: Percutaneous Closure Strategy.
abstract: Regurgitation due to a paravalvular leak (PVL) is a complication that may affect patients undergoing surgical mechanical or bioprosthetic heart valve replacement. PVL can also occur after transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis and is associated with significantly worse outcomes. We report a case in which different closure strategies and devices were attempted and required to percutaneously close a severe PVL after TAVI in a patient with prohibitive surgical risk.
authors.affiliation: Department of Invasive Cardiology, Humanitas Research Hospital, Rozzano (Milan), Italy. Electronic address: marco_luciano.rossi@humanitas.it.
authors.forename: Marco Luciano
authors.initials: ML
authors.lastname: Rossi
authors.affiliation: Department of Invasive Cardiology, Humanitas Research Hospital, Rozzano (Milan), Italy.
authors.forename: Guido
authors.initials: G
authors.lastname: Belli
authors.affiliation: Department of Invasive Cardiology, Humanitas Research Hospital, Rozzano (Milan), Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Pagnotta
authors.affiliation: Department of Invasive Cardiology, Humanitas Research Hospital, Rozzano (Milan), Italy.
authors.forename: Carla
authors.initials: C
authors.lastname: Lucarelli
authors.affiliation: Department of Invasive Cardiology, Humanitas Research Hospital, Rozzano (Milan), Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Presbitero
mesh_terms: D000369:Aged, 80 and over; D001022:Aortic Valve Insufficiency / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D006328:Cardiac Catheterization; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans
keywords: Paravalular leak (PVL); Percutaneous closure devices; Percutaneous valve-in-valve placement; Severe aortic regurgitation; Transcatheter aortic valve implantation (TAVI)