title: Combined disease with pulmonary arterial hypertension and pulmonary venous hypertension revealed after treatment of heart failure with preserved ejection fraction in a case with primary Sjögren syndrome.
abstract: A 49-year-old woman with primary Sjögren syndrome initially developed pulmonary venous hypertension (PVH) due to heart failure with preserved ejection fraction. Endomyocardial biopsy specimens showed mild myocardial fibrosis. Pulmonary arterial hypertension (PAH) was revealed after the treatment with diuretics. During the treatment for PAH using upfront combination with pulmonary vasodilators and immunosuppressants, the patient developed combined disease with PAH and PVH. A careful hemodynamic assessment is necessary in such cases.
authors.affiliation: a Division of Rheumatology and Allergology, St. Marianna University School of Medicine , Sugao, Miyamae, Kawasaki City, Kanagawa Prefecture , Japan.
authors.forename: Yoshioki
authors.initials: Y
authors.lastname: Yamasaki
authors.affiliation: b Division of Cardiology, St. Marianna University School of Medicine , Sugao, Miyamae, Kawasaki City, Kanagawa Prefecture , Japan.
authors.forename: Kengo
authors.initials: K
authors.lastname: Suzuki
authors.affiliation: b Division of Cardiology, St. Marianna University School of Medicine , Sugao, Miyamae, Kawasaki City, Kanagawa Prefecture , Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Kamijima
authors.affiliation: a Division of Rheumatology and Allergology, St. Marianna University School of Medicine , Sugao, Miyamae, Kawasaki City, Kanagawa Prefecture , Japan.
authors.forename: Yusa
authors.initials: Y
authors.lastname: Asari
authors.affiliation: a Division of Rheumatology and Allergology, St. Marianna University School of Medicine , Sugao, Miyamae, Kawasaki City, Kanagawa Prefecture , Japan.
authors.forename: Kosei
authors.initials: K
authors.lastname: Tsuchida
authors.affiliation: a Division of Rheumatology and Allergology, St. Marianna University School of Medicine , Sugao, Miyamae, Kawasaki City, Kanagawa Prefecture , Japan.
authors.forename: Machiko
authors.initials: M
authors.lastname: Mizushima
authors.affiliation: a Division of Rheumatology and Allergology, St. Marianna University School of Medicine , Sugao, Miyamae, Kawasaki City, Kanagawa Prefecture , Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Okazaki
authors.affiliation: b Division of Cardiology, St. Marianna University School of Medicine , Sugao, Miyamae, Kawasaki City, Kanagawa Prefecture , Japan.
authors.forename: Yoshihiro J
authors.initials: YJ
authors.lastname: Akashi
authors.affiliation: a Division of Rheumatology and Allergology, St. Marianna University School of Medicine , Sugao, Miyamae, Kawasaki City, Kanagawa Prefecture , Japan.
authors.forename: Shoichi
authors.initials: S
authors.lastname: Ozaki
authors.affiliation: a Division of Rheumatology and Allergology, St. Marianna University School of Medicine , Sugao, Miyamae, Kawasaki City, Kanagawa Prefecture , Japan.
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Yamada
mesh_terms: D006328:Cardiac Catheterization; D005260:Female; D006333:Heart Failure / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000503:physiopathology; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications* / Q000503:physiopathology; D013318:Stroke Volume / Q000502:physiology*
keywords: Heart failure with preserved ejection fraction; Sjögren syndrome; pulmonary arterial hypertension; pulmonary venous hypertension