title: Association of Serum Uric Acid with Body Mass Index: A Cross-Sectional Study from Jiangsu Province, China.
abstract: BACKGROUND
  Body mass index (BMI) has been demonstrated to be associated with serum uric acid (SUA) level in many developed countries, however, there is still a lack of large sample study in Jiangsu Province, one of the most economically developed regions in China, where fat-rich diet is common.
  
  
  METHODS
  Through retrospective analysis in healthy subjects, we determined the association of BMI with hyperuricemia risk. Data of 39,736 participants from January 2011 to June 2013 in China were analyzed for parameters including physical examinations and biochemical blood analysis.
  
  
  RESULTS
  On univariate analysis, SUA was positively correlated with age, SBP, DBP, BMI, FPG, red blood cell count, hemoglobin, white blood cell count, platelet, cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, ALT, AST, bilirubin, albumin, BUN and creatinine. SUA was significantly elevated in a linear fashion as BMI increased, and SUA in obesity was significantly higher than underweight. The prevalence of hyperuricemia remained approximately 2.98 times greater among individuals with overweight, and 5.96 times greater among obesity, compared to individuals with underweight.
  
  
  CONCLUSIONS
  There is a positive relationship between BMI and SUA among healthy subjects in Jiangsu province, China.
authors.affiliation: 1. Dept. of Gastroenterology, Huai'an First People's Hospital, Nanjing Medical University , Huai'an, P. R. China.
authors.forename: Honggang
authors.initials: H
authors.lastname: Wang
authors.affiliation: 2. Dept. of Medical Centerfor Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University , Nanjing, P.R. China.
authors.forename: Lizhen
authors.initials: L
authors.lastname: Wang
authors.affiliation: 1. Dept. of Gastroenterology, Huai'an First People's Hospital, Nanjing Medical University , Huai'an, P. R. China.
authors.forename: Rui
authors.initials: R
authors.lastname: Xie
authors.affiliation: 1. Dept. of Gastroenterology, Huai'an First People's Hospital, Nanjing Medical University , Huai'an, P. R. China.
authors.forename: Weijie
authors.initials: W
authors.lastname: Dai
authors.affiliation: 1. Dept. of Gastroenterology, Huai'an First People's Hospital, Nanjing Medical University , Huai'an, P. R. China.
authors.forename: Chengcheng
authors.initials: C
authors.lastname: Gao
authors.affiliation: 1. Dept. of Gastroenterology, Huai'an First People's Hospital, Nanjing Medical University , Huai'an, P. R. China.
authors.forename: Peng
authors.initials: P
authors.lastname: Shen
authors.affiliation: 2. Dept. of Medical Centerfor Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University , Nanjing, P.R. China.
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Huang
authors.affiliation: 2. Dept. of Medical Centerfor Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University , Nanjing, P.R. China.
authors.forename: Faming
authors.initials: F
authors.lastname: Zhang
authors.affiliation: 1. Dept. of Gastroenterology, Huai'an First People's Hospital, Nanjing Medical University , Huai'an, P. R. China.
authors.forename: Xiaozhong
authors.initials: X
authors.lastname: Yang
authors.affiliation: 2. Dept. of Medical Centerfor Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University , Nanjing, P.R. China.
authors.forename: Guozhong
authors.initials: G
authors.lastname: Ji
keywords: Association; Body mass index; Serum uric acid