title: Accuracy of the Timed Up and Go test for predicting sarcopenia in elderly hospitalized patients.
abstract: OBJECTIVE
  The ability of the Timed Up and Go test to predict sarcopenia has not been evaluated previously. The objective of this study was to evaluate the accuracy of the Timed Up and Go test for predicting sarcopenia in elderly hospitalized patients.
  
  
  METHODS
  This cross-sectional study analyzed 68 elderly patients (≥60 years of age) in a private hospital in the city of Salvador-BA, Brazil, between the 1st and 5th day of hospitalization. The predictive variable was the Timed Up and Go test score, and the outcome of interest was the presence of sarcopenia (reduced muscle mass associated with a reduction in handgrip strength and/or weak physical performance in a 6-m gait-speed test). After the descriptive data analyses, the sensitivity, specificity and accuracy of a test using the predictive variable to predict the presence of sarcopenia were calculated.
  
  
  RESULTS
  In total, 68 elderly individuals, with a mean age 70.4±7.7 years, were evaluated. The subjects had a Charlson Comorbidity Index score of 5.35±1.97. Most (64.7%) of the subjects had a clinical admission profile; the main reasons for hospitalization were cardiovascular disorders (22.1%), pneumonia (19.1%) and abdominal disorders (10.2%). The frequency of sarcopenia in the sample was 22.1%, and the mean length of time spent performing the Timed Up and Go test was 10.02±5.38 s. A time longer than or equal to a cutoff of 10.85 s on the Timed Up and Go test predicted sarcopenia with a sensitivity of 67% and a specificity of 88.7%. The accuracy of this cutoff for the Timed Up and Go test was good (0.80; IC=0.66-0.94; p=0.002).
  
  
  CONCLUSIONS
  The Timed Up and Go test was shown to be a predictor of sarcopenia in elderly hospitalized patients.
authors.affiliation: Department of Physiotherapy, University of Bahia, Salvador, BA, Brazil.
authors.forename: Bruno Prata
authors.initials: BP
authors.lastname: Martinez
authors.affiliation: Department of Physiotherapy, University of Bahia, Salvador, BA, Brazil.
authors.forename: Isabela Barboza
authors.initials: IB
authors.lastname: Gomes
authors.affiliation: Department of Physiotherapy, University of Bahia, Salvador, BA, Brazil.
authors.forename: Carolina Santana de
authors.initials: CS
authors.lastname: Oliveira
authors.affiliation: Department of Physiotherapy, University of Bahia, Salvador, BA, Brazil.
authors.forename: Isis Resende
authors.initials: IR
authors.lastname: Ramos
authors.affiliation: Department of Physiotherapy, University of Bahia, Salvador, BA, Brazil.
authors.forename: Mônica Diniz Marques
authors.initials: MD
authors.lastname: Rocha
authors.affiliation: Programa de Pós-graduação em Reabilitação e Inclusão, Biociências e Reabilitação, Centro Universitário Metodista, Porto Alegre, RS, Brazil.
authors.forename: Luiz Alberto
authors.initials: LA
authors.lastname: Forgiarini Júnior
authors.affiliation: Department of Physiotherapy, University of Bahia, Salvador, BA, Brazil.
authors.forename: Fernanda Warken Rosa
authors.initials: FW
authors.lastname: Camelier
authors.affiliation: Bahia School of Medicine and Public Health, University of Bahia, Salvador, BA, Brazil.
authors.forename: Aquiles Assunção
authors.initials: AA
authors.lastname: Camelier
mesh_terms: D000058:Accidental Falls; D000368:Aged; D003072:Cognition Disorders / Q000175:diagnosis; D003430:Cross-Sectional Studies; D061827:Dimensional Measurement Accuracy; D004185:Disability Evaluation; D005260:Female; D005684:Gait / Q000502:physiology; D015577:Geriatric Assessment / Q000379:methods*; D006760:Hospitalization; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D051346:Mobility Limitation; D053580:Muscle Strength / Q000502:physiology; D018482:Muscle, Skeletal / Q000502:physiology; D011237:Predictive Value of Tests; D055948:Sarcopenia / Q000175:diagnosis*; D013996:Time and Motion Studies