title: Influenza activity - United States, 2014-15 season and composition of the 2015-16 influenza vaccine.
abstract: During the 2014-15 influenza season in the United States, influenza activity increased through late November and December before peaking in late December. Influenza A (H3N2) viruses predominated, and the prevalence of influenza B viruses increased late in the season. This influenza season, similar to previous influenza A (H3N2)-predominant seasons, was moderately severe with overall high levels of outpatient illness and influenza-associated hospitalization, especially for adults aged ≥65 years. The majority of circulating influenza A (H3N2) viruses were different from the influenza A (H3N2) component of the 2014-15 Northern Hemisphere seasonal vaccines, and the predominance of these drifted viruses resulted in reduced vaccine effectiveness. This report summarizes influenza activity in the United States during the 2014-15 influenza season (September 28, 2014-May 23, 2015) and reports the recommendations for the components of the 2015-16 Northern Hemisphere influenza vaccine.
authors.forename: Grace D
authors.initials: GD
authors.lastname: Appiah
authors.forename: Lenee
authors.initials: L
authors.lastname: Blanton
authors.forename: Tiffany
authors.initials: T
authors.lastname: D'Mello
authors.forename: Krista
authors.initials: K
authors.lastname: Kniss
authors.forename: Sophie
authors.initials: S
authors.lastname: Smith
authors.forename: Desiree
authors.initials: D
authors.lastname: Mustaquim
authors.forename: Craig
authors.initials: C
authors.lastname: Steffens
authors.forename: Rosaline
authors.initials: R
authors.lastname: Dhara
authors.forename: Jessica
authors.initials: J
authors.lastname: Cohen
authors.forename: Sandra S
authors.initials: SS
authors.lastname: Chaves
authors.forename: Joseph
authors.initials: J
authors.lastname: Bresee
authors.forename: Teresa
authors.initials: T
authors.lastname: Wallis
authors.forename: Xiyan
authors.initials: X
authors.lastname: Xu
authors.forename: Anwar Isa
authors.initials: AI
authors.lastname: Abd Elal
authors.forename: Larisa
authors.initials: L
authors.lastname: Gubareva
authors.forename: David E
authors.initials: DE
authors.lastname: Wentworth
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Katz
authors.forename: Daniel
authors.initials: D
authors.lastname: Jernigan
authors.forename: Lynnette
authors.initials: L
authors.lastname: Brammer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D046688:Child Mortality; D002675:Child, Preschool; D014644:Genetic Variation; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics / Q000302:isolation & purification; D053122:Influenza A Virus, H3N2 Subtype / Q000235:genetics / Q000302:isolation & purification; D009980:Influenza A virus / Q000235:genetics / Q000302:isolation & purification*; D009981:Influenza B virus / Q000235:genetics / Q000302:isolation & purification*; D007252:Influenza Vaccines / Q000737:chemistry; D007251:Influenza, Human / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control / Q000821:virology; D008875:Middle Aged; D010045:Outpatients / Q000706:statistics & numerical data; D011014:Pneumonia / Q000401:mortality; D011159:Population Surveillance; D012621:Seasons; D014481:United States / Q000453:epidemiology; D055815:Young Adult
chemical_list: D007252:Influenza Vaccines