title: TiQuant: software for tissue analysis, quantification and surface reconstruction.
abstract: BACKGROUND
  TiQuant is a modular software tool for efficient quantification of biological tissues based on volume data obtained by biomedical image modalities. It includes a number of versatile image and volume processing chains tailored to the analysis of different tissue types which have been experimentally verified. TiQuant implements a novel method for the reconstruction of three-dimensional surfaces of biological systems, data that often cannot be obtained experimentally but which is of utmost importance for tissue modelling in systems biology.
  
  
  METHODS
  TiQuant is freely available for non-commercial use at msysbio.com/tiquant. Windows, OSX and Linux are supported.
  
  
  BACKGROUND
  hoehme@uni-leipzig.de
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Interdisciplinary Centre for Bioinformatics (IZBI), University of Leipzig, Germany.
authors.forename: Adrian
authors.initials: A
authors.lastname: Friebel
authors.affiliation: Interdisciplinary Centre for Bioinformatics (IZBI), University of Leipzig, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Neitsch
authors.affiliation: Interdisciplinary Centre for Bioinformatics (IZBI), University of Leipzig, Germany.
authors.forename: Tim
authors.initials: T
authors.lastname: Johann
authors.affiliation: Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany, Department of Forensic Medicine and Veterinary Toxicology, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt and.
authors.forename: Seddik
authors.initials: S
authors.lastname: Hammad
authors.affiliation: Leibniz Research Centre for Working Environment and Human Factors (IfADo), Dortmund, Germany.
authors.forename: Jan G
authors.initials: JG
authors.lastname: Hengstler
authors.affiliation: Interdisciplinary Centre for Bioinformatics (IZBI), University of Leipzig, Germany, Institut National de Recherche en Informatique et en Automatique (INRIA) Unit Rocquencourt, Le Chesnay Cedex, France.
authors.forename: Dirk
authors.initials: D
authors.lastname: Drasdo
authors.affiliation: Interdisciplinary Centre for Bioinformatics (IZBI), University of Leipzig, Germany, Institut National de Recherche en Informatique et en Automatique (INRIA) Unit Rocquencourt, Le Chesnay Cedex, France.
authors.forename: Stefan
authors.initials: S
authors.lastname: Hoehme
mesh_terms: D000465:Algorithms; D003196:Computer Graphics; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D009928:Organ Specificity; D012984:Software; D049490:Systems Biology / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods