title: Evaluation of Artisan aphakic intraocular lens in cases of pediatric aphakia with insufficient capsular support.
abstract: OBJECTIVE
  To evaluate the visual outcomes and complications after Artisan iris-claw lens implantation in aphakic children with insufficient capsular support.
  
  
  METHODS
  In this prospective, interventional noncontrolled study, aphakic eyes of consecutive patients >2 years of age with insufficient capsular support who underwent Artisan intraocular lens (IOL) implantation between June 2011 and December 2012 were followed for 1 year. Patients with anterior chamber depth <3 mm, central endothelial cell density (CECD) <2500 cells/mm(²), uncontrolled glaucoma, or uveitis were excluded. Best-corrected visual acuity, intraocular pressure (IOP), and CECD were measured at 1, 6, and 12 months postoperatively.
  
  
  RESULTS
  A total of 25 aphakic eyes of 18 patients (mean age, 7.86 ± 3.08 years) with insufficient capsular support for a standard posterior chamber IOL were included, 18 eyes with subluxated lens and 7 following trauma. The mean preoperative logMAR best-corrected visual acuity for traumatic aphakic patients was 0.95 ± 0.36; for patients with subluxation, 0.7 ± 0.26. Values improved at 1 year to 0.38 ± 0.15 (P < 0.002) and 0.3 ± 0.2 (P < 0.0001), respectively. One year after surgery the CECD (2892.64 ± 441.79 cells/mm(²)) was significantly reduced from the preoperative and 1 month postoperative values (3573.36 ± 468.9 cells/mm(2), 3081 ± 495 cells/mm(²); P < 0.0001, P < 0.02 resp.). Two cases (8%) developed traumatic dislocation. Pupillary block occurred in 1 case (4%).
  
  
  CONCLUSIONS
  Artisan IOL implantation for pediatric aphakia achieved a good visual outcome.
authors.affiliation: Ophthalmology Department, Faculty of Medicine, Cairo University & Research Institute of Ophthalmology, Cairo, Egypt.
authors.forename: Ghada I
authors.initials: GI
authors.lastname: Gawdat
authors.affiliation: Ophthalmology Department, Faculty of Medicine, Cairo University & Research Institute of Ophthalmology, Cairo, Egypt.
authors.forename: Sameh G
authors.initials: SG
authors.lastname: Taher
authors.affiliation: Ophthalmology Department, Faculty of Medicine, Cairo University & Research Institute of Ophthalmology, Cairo, Egypt. Electronic address: marwasalama2177@yahoo.com.
authors.forename: Marwa M
authors.initials: MM
authors.lastname: Salama
authors.affiliation: Ophthalmology Department, Faculty of Medicine, Cairo University & Research Institute of Ophthalmology, Cairo, Egypt.
authors.forename: Adel A
authors.initials: AA
authors.lastname: Ali
mesh_terms: D000293:Adolescent; D001036:Aphakia, Postcataract / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D055954:Corneal Endothelial Cell Loss / Q000175:diagnosis; D005131:Eye Injuries / Q000209:etiology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007903:Lens Capsule, Crystalline / Q000473:pathology*; D019654:Lens Implantation, Intraocular / Q000379:methods*; D007906:Lens Subluxation / Q000209:etiology / Q000601:surgery; D007910:Lenses, Intraocular; D008297:Male; D011446:Prospective Studies; D011474:Prosthesis Design; D014792:Visual Acuity / Q000502:physiology*