title: The dark side of T memory stem cells.
abstract: In this issue of Blood, Nagai et al provide evidence that adult T-cell leukemia is hierarchically organized and sustained by a small population of transformed T memory stem cells.
authors.affiliation: NATIONAL INSTITUTES OF HEALTH.
authors.forename: Luca
authors.identifier: http://orcid.org/0000-0003-2239-3282
authors.initials: L
authors.lastname: Gattinoni
mesh_terms: D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D002454:Cell Differentiation / Q000276:immunology*; D049109:Cell Proliferation; D005260:Female; D015368:Human T-lymphotropic virus 1 / Q000276:immunology*; D006801:Humans; D007156:Immunologic Memory; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000276:immunology*; D008297:Male