title: Loop nucleotides impact the stability of intrastrand i-motif structures at neutral pH.
abstract: The stability of i-motif structures at neutral pH is of interest due to the potential of these structures to impact gene expression. A systematic investigation of loop sequence and length revealed that certain loop nucleobases stabilize i-motif quadruplexes.
authors.affiliation: Frontier Institute for Biomolecular Engineering Research (FIBER), Konan University, 8-9-1 Minatojima-minamimachi, Chuo-ku, Kobe 650-0047, Japan. sugimoto@konan-u.ac.jp.
authors.forename: Taiga
authors.initials: T
authors.lastname: Fujii
authors.forename: Naoki
authors.initials: N
authors.lastname: Sugimoto
mesh_terms: D006863:Hydrogen-Ion Concentration; D059372:Nucleotide Motifs; D009711:Nucleotides / Q000737:chemistry* / Q000235:genetics; D013816:Thermodynamics
chemical_list: D009711:Nucleotides