title: From shellfish poisoning to neuroscience.
abstract: In this issue of Structure, Bourne et al. (2015) report X-ray structures of acetylcholine binding protein with two fast-acting phycotoxins from the pinnatoxin family. The results may pave the way for development of new CNS-penetrant and subtype-selective nAChR antagonists.
authors.affiliation: Danish Research Institute of Translational Neuroscience - DANDRITE, Nordic-EMBL Partnership for Molecular Medicine, Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 10C, DK-8000 Aarhus C, Denmark.
authors.forename: Azadeh
authors.initials: A
authors.lastname: Shahsavar
authors.affiliation: Faculty of Pharmacy, University of Sydney, Sydney, NSW 2006, Australia. Electronic address: thomas.balle@sydney.edu.au.
authors.forename: Thomas
authors.initials: T
authors.lastname: Balle
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000737:chemistry*; D008387:Marine Toxins / Q000737:chemistry*; D008958:Models, Molecular; D013141:Spiro Compounds / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D007097:Imines; D047028:Macrocyclic Compounds; D008387:Marine Toxins; D013141:Spiro Compounds