title: Management of necrotising appendicitis associated with widespread necrotising enterocolitis of the small and large bowel and perforated duodenal ulcer.
abstract: A 7-year-old boy presented in septic shock secondary to appendicitis with generalised peritonitis. Following crystalloid resuscitation, he underwent surgery. Faecopurulent contamination and free air were found. This was secondary to a perforated and gangrenous appendix, multiple large and small bowel segments with perforations, patches of necrosis, interspersed with healthy bowel and segments of questionable viability. There was also a perforated duodenal ulcer. Necrotic segments were resected using a 'clip-and-drop' technique to shorten operative duration and guide resection to preserve bowel length. After six laparotomies and multiple bowel resections, the child was discharged home with an ileostomy that was subsequently reversed. He is currently on a normal diet and pursuing all activities appropriate for his age. Perforated appendicitis can be associated with widespread bowel necrosis and multiple perforations. A conservative damage limitation approach using the 'clip-and-drop' technique and relook laparotomies is useful in the management of extensive bowel necrosis in children.
authors.affiliation: Department of Surgery, University of Toronto, Toronto, Canada.
authors.forename: Vaibhav
authors.initials: V
authors.lastname: Gupta
authors.affiliation: Pediatric Surgery Unit, Sapienza University of Rome, Rome, Italy.
authors.forename: Augusto
authors.initials: A
authors.lastname: Zani
authors.affiliation: Department of Paediatric Surgery, QMC, Nottingham, UK.
authors.forename: Paul
authors.initials: P
authors.lastname: Jackson
authors.affiliation: Department of Paediatric Surgery, QMC, Nottingham, UK.
authors.forename: Shailinder
authors.initials: S
authors.lastname: Singh
mesh_terms: D001062:Appendectomy; D001064:Appendicitis / Q000150:complications / Q000601:surgery*; D001065:Appendix / Q000473:pathology / Q000601:surgery*; D002648:Child; D013505:Digestive System Surgical Procedures; D004381:Duodenal Ulcer / Q000209:etiology / Q000601:surgery*; D020345:Enterocolitis, Necrotizing / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology / Q000601:surgery*; D007420:Intestine, Large / Q000473:pathology / Q000601:surgery; D007421:Intestine, Small / Q000473:pathology / Q000601:surgery; D008297:Male; D009336:Necrosis; D010439:Peptic Ulcer Perforation / Q000209:etiology / Q000601:surgery*; D010538:Peritonitis / Q000209:etiology / Q000601:surgery