title: Staged resection of bilobar colorectal liver metastases: surgical strategies.
abstract: BACKGROUND
  Radical resection is the treatment of choice for colorectal liver metastases (CLM). Unfortunately, only about 20 % of patients present with initially resectable disease, in most cases due to bilobar disease. In the last two decades, major achievements have been made to extend surgical indications to patients with bilobar CLM, such as two-stage hepatectomy with or without portal vein occlusion and associating liver partition and portal vein ligation for staged hepatectomy (ALPPS).
  
  
  OBJECTIVE
  The purpose of this review article was to summarize current surgical approaches and their safety and efficacy for patients with initially unresectable bilobar CLM.
  
  
  CONCLUSIONS
  In selected patients, two-stage hepatectomy and ALPPS are efficient and safe to convert unresectable to resectable CLM. Further studies are required to evaluate long-term outcome of these procedures.
authors.affiliation: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, Fetscherstr. 74, D-01307, Dresden, Germany.
authors.forename: Cui
authors.initials: C
authors.lastname: Yang
authors.forename: Nuh N
authors.initials: NN
authors.lastname: Rahbari
authors.forename: Sören Torge
authors.initials: ST
authors.lastname: Mees
authors.forename: Felix
authors.initials: F
authors.lastname: Schaab
authors.forename: Moritz
authors.initials: M
authors.lastname: Koch
authors.forename: Jürgen
authors.initials: J
authors.lastname: Weitz
authors.forename: Christoph
authors.initials: C
authors.lastname: Reissfelder
mesh_terms: D015179:Colorectal Neoplasms / Q000473:pathology*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D018579:Patient Selection; D016896:Treatment Outcome