title: Influence of medical nutrition therapy on borderline glucose intolerance in pregnant Taiwanese women.
abstract: OBJECTIVE
  To investigate the influence of medical nutrition therapy (MNT) on borderline glucose intolerance (BGI) in pregnant Taiwanese women.
  
  
  METHODS
  A total of 5194 singleton pregnant women were enrolled in this prospective, non-randomized study. The participants were subjected to the 50 g 1-h glucose challenge test (GCT) and 100 g 3-h oral glucose tolerance test (OGTT) to screening gestational diabetes mellitus (GDM). BGI was defined as a positive GCT and normal OGTT results. GDM was defined as a positive GCT and abnormal OGTT results. The women were categorized into the following groups: (1) GCT-negative, n = 3881; (2) BGI with MNT, n = 273; (3) BGI without MNT, n = 712; and (4) GDM, n = 328. Multiple logistic analyses were used to estimate the risks of pregnancy outcomes.
  
  
  RESULTS
  The odds ratios (95% confidence interval) for total cesareans, third- or fourth-degree perineal lacerations, gestational hypertension or preeclampsia and macrosomia were 1.24 (1.04-1.49), 1.55 (1.06-1.28), 1.78 (1.21-2.61) and 2.50 (1.28-4.91) in the BGI without MNT group compared to the GCT-negative group. There was no difference between BGI with MNT and GCT-negative groups.
  
  
  CONCLUSIONS
  Women with BGI who did not receive MNT had increased risks of adverse pregnancy outcomes, whereas who received MNT had no different risk with GCT-negative women.
authors.affiliation: a Department of Obstetrics and Gynecology and.
authors.forename: Tsung-Chin
authors.initials: TC
authors.lastname: Ho
authors.affiliation: b Department of Internal Medicine , Ditmanson Medical Foundation Chia-Yi Christian Hospital , Taiwan , Republic of China .|c Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University , Taipei, Taiwan , Republic of China .|d Department of Medical Research .
authors.forename: Yuan-Horng
authors.initials: YH
authors.lastname: Yan
authors.affiliation: a Department of Obstetrics and Gynecology and.|d Department of Medical Research .|e Department of Community Health , and.
authors.forename: Mei-Chun
authors.initials: MC
authors.lastname: Lu
authors.affiliation: f Department of Nutrition , Ditmanson Medical Foundation Chia-Yi Christian Hospital , Taiwan , Republic of China.
authors.forename: Cheng-Wei
authors.initials: CW
authors.lastname: Yu
authors.affiliation: a Department of Obstetrics and Gynecology and.
authors.forename: Panchalli
authors.initials: P
authors.lastname: Wang
mesh_terms: D000328:Adult; D001786:Blood Glucose; D005260:Female; D018149:Glucose Intolerance / Q000178:diet therapy*; D005951:Glucose Tolerance Test; D006801:Humans; D044623:Nutrition Therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000178:diet therapy*; D011256:Pregnancy Outcome; D013624:Taiwan; D055815:Young Adult
chemical_list: D001786:Blood Glucose
keywords: Borderline glucose intolerance; excessive weight gain; gestational diabetes mellitus; medical nutrition therapy; pregnancy outcome