title: Utility of MPT64 Antigen Detection for Rapid Confirmation of Mycobacterium tuberculosis Complex.
abstract: BACKGROUND
  Rapid differentiation of the Mycobacterium tuberculosis complex (MTBC) and mycobacteria other than tuberculosis (MOTT) is crucial to facilitate early and effective treatment of the patients. Clinical presentation of MTBC and MOTT is not always very clear and routine conventional methods are time consuming.
  
  
  METHODS
  In the present study, the MPT64 protein detection-based immunochomatographic test (SD Bioline Kit, Standard Diagnostics, Inc., Korea) was compared with the conventional biochemical method.
  
  
  RESULTS
  The sensitivity, specificity, positive predictive, and negative predictive values of the SD AgMPT64 kit were found to be 100, 96.4, 98.72, and 100%, respectively.
  
  
  CONCLUSIONS
  Our results have demonstrated that the SD bioline kit is a rapid, reliable method and it can be used in the Revised National Tuberculosis Control Program (RNTCP) of India, for the appropriate management of tuberculosis.
authors.affiliation: Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg, New Delhi, India.
authors.forename: Jyoti
authors.initials: J
authors.lastname: Arora
authors.affiliation: Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg, New Delhi, India.
authors.forename: Gavish
authors.initials: G
authors.lastname: Kumar
authors.affiliation: Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg, New Delhi, India.
authors.forename: Ajoy Kumar
authors.initials: AK
authors.lastname: Verma
authors.affiliation: Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg, New Delhi, India.
authors.forename: Manpreet
authors.initials: M
authors.lastname: Bhalla
authors.affiliation: Department of TB and Chest, National Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg, New Delhi, India.
authors.forename: Rohit
authors.initials: R
authors.lastname: Sarin
authors.affiliation: Department of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, Sri Aurobindo Marg, New Delhi, India.
authors.forename: Vithal Prasad
authors.initials: VP
authors.lastname: Myneedu
keywords: Biochemical identification; M. tuberculosis complex; MPT64 antigen