title: A Randomized, Controlled Trial of Levonorgestrel Vs. The Yuzpe Regimen as Emergency Contraception Method among Iranian Women.
abstract: BACKGROUND
  We aimed to compare acceptability of Levonorgestrel with the Yuzpe regimen among Iranian women based on their side-effects and resulting changes in the amount and pattern of menses.
  
  
  METHODS
  Five hundred twenty nine participants aged 15-49 having regular menses and one act of unprotected intercourse within 72 h were included in the double-blind, controlled trial in 2006-2007 and randomly assigned into LNG (n=263) and HD (n=266) groups, receiving Levonorgestrel 0.75 mg given 12 h apart and ethinyl estradiol 100 μg plus 0.5 mg Levonorgestrel 0.5 mg repeated after 12 h, respectively.
  
  
  RESULTS
  The participants receiving Levonorgestrel experienced significantly lower side-effects in the case of nausea, vomiting, and dizziness (P<0.05). The changes occurred in the amount and pattern of menses were the same for both groups (P>0.05). No significant difference was observed between the efficiencies of the treatments.
  
  
  CONCLUSIONS
  Significantly lower side-effects of Levonorgestrel can be considered as greater acceptability and translated to higher efficiency.
authors.affiliation: 1. Dept. of Anatomy, School of Medicine, Tehran University of Medical Sciences , Tehran, Iran.
authors.forename: Fatemeh Sadat
authors.initials: FS
authors.lastname: Hoseini
authors.affiliation: 2. Dept. of Population, Family and School Health, Ministry of Health and Medical Education , Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Eslami
authors.affiliation: 3. Family Planning Office, Gilan University of Medical Sciences , Rasht, Iran.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Abbasi
authors.affiliation: 3. Family Planning Office, Gilan University of Medical Sciences , Rasht, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Noroozi Fashkhami
authors.affiliation: 3. Family Planning Office, Gilan University of Medical Sciences , Rasht, Iran.
authors.forename: Soheila
authors.initials: S
authors.lastname: Besharati
keywords: Emergency contraception; Levonorgestrel; Side-effects; Yuzpe regimen