title: Effectiveness of Relapse Prevention Cognitive-Behavioral Model in Opioid-Dependent Patients Participating in the Methadone Maintenance Treatment in Iran.
abstract: BACKGROUND
  To evaluate the effectiveness of a relapse prevention cognitive-behavioral model, based on Marlatt treatment approach, in Opioid-dependent patients participating in the Methadone Maintenance Treatment (MMT) in Iran.
  
  
  METHODS
  The study consisted of 92 individuals treated with methadone in Iranian National Center of Addiction Studies (INCAS). Participants were randomized into two groups: educational intervention group (N=46) and control group (N=46). The intervention was comprised of 10 weekly 90 minute sessions, done during a period of 2.5 months based on the most high risk situations determined using Inventory Drug Taking Situation instrument. Relapse was defined as not showing up for MMT, drug use for at least 5 continuous days, and a positive urinary morphine test.
  
  
  RESULTS
  While, only 36.4% of the intervention group relapsed into drug use, 63.6% of the control group relapsed. The result of the logistic regressions showed that the odd ratio of the variable of intervention program for the entire follow up period was 0.43 (P<0.01). Further, the odd ratio of this variable in one month, three months, and 195 days after the therapy were 0.48 (P<.03), 0.31 (P<.02), and 0.13 (P<.02) respectively that revealed that on average, the probability of relapse among individuals in the intervention group was lower than patients in control group.
  
  
  CONCLUSIONS
  Relapse prevention model based on Marlatt treatment approach has an effective role in decreasing relapse rate. This model can be introduced as a complementary therapy in patients treated with methadone maintenance.
authors.affiliation: Dept .of Public Health, School of Health, Kurdistan University of Medical Science, Sanandaj, Iran. ; Iranian National Center for Addiction Studies, Tehran University of Medical sciences, Tehran, Iran.
authors.forename: Tahereh
authors.initials: T
authors.lastname: Pashaei
authors.affiliation: Dept. of Health education and Promotion, School of Public Health, Tehran University of Medical Sciences, Tehran Iran.
authors.forename: Davoud
authors.initials: D
authors.lastname: Shojaeizadeh
authors.affiliation: Dept .of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Rahimi Foroushani
authors.affiliation: Dept .of Health and social Demography, Faculty of Social Sciences, University of Tehran, Tehran, Iran.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Ghazitabatabae
authors.affiliation: Dept .of Management and Health Economics, School of Public Health, University of Medical Sciences, Tehran, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Moeeni
authors.affiliation: Dept .of Health education and Promotion, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Rajati
authors.affiliation: Dept .of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Emran
authors.initials: E
authors.lastname: M Razzaghi
keywords: Methadone; Opioid addiction; Relapse; Retention; Treatment