title: Review of the chemistry and pharmacology of 7-Methyljugulone.
abstract: BACKGROUND
  Naphthoquinone is a class of phenolic compounds derived from naphthalene. 7-Methyljuglone (7-MJ) is a naphthoquinone also known as ramentaceone or 6-Methyl-8-hydroxy-1,4-naphthoquinone or 5-Hydroxy-7-methyl-1,4-naphthoquinone or 7-Methyl-5-hydroxy-1,4-naphthoquinone or 5-Hydroxy-7-methyl-,1,4-naphtoquinone or 7-Methyl-5-hydroxynaphthalene-1,4-dione. This compound is a biologically active naphtoquinone, with a molecular weight of 188 g/mol mostly isolated in the genus Diospyros and Euclea.
  
  
  OBJECTIVE
  This review was aimed at providing available chemically and pharmacological data on 7-MJ.
  
  
  METHODS
  The chemical and pharmacological data were retrieved from the well-known scientific websites such as Pubmed, Google Scholar, Reaxys, Scirus, Scopus, Sciencedirect, Web-of-knowledge and Scifinder.
  
  
  RESULTS
  7-MJ was reported to have a variety of pharmacological activities such as antibacterial, antifungal, anticancer, antitubercular, anti-inflammatory and antiviral activities. The hemi-synthesis of the compound have been described.
  
  
  CONCLUSIONS
  The present review pooled out together the knowledge on 7-MJ, and can serve as the start point for future research and valorization accomplishments.
authors.affiliation: Department of Biochemistry, Faculty of science, University of Dschang, Cameroon.
authors.forename: Armelle T
authors.initials: AT
authors.lastname: Mbaveng
authors.affiliation: Department of Biochemistry, Faculty of science, University of Dschang, Cameroon.
authors.forename: Victor
authors.initials: V
authors.lastname: Kuete
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D053898:Biosynthetic Pathways / Q000187:drug effects*; D006801:Humans; D009285:Naphthoquinones / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: C517013:7-methyljuglone; D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D000995:Antitubercular Agents; D000998:Antiviral Agents; D009285:Naphthoquinones
keywords: 7-methyljugulone; biosynthesis; in vitro synthesis; pharmacology