title: Development and Validation of the Simplified Chinese Version of EORTC QLQ-HCC18 for Patients with Hepatocellular Carcinoma.
abstract: This study aimed to develop and validate the Simplified Chinese Version of the Quality of Life Questionnaire for Hepatocellular Carcinoma (the QLQ-HCC18). It was developed by the strict translation procedure of EORTC guidelines, and the psychometrics were evaluated on a sample of 114 patients. The internal consistency Cronbach's α were greater than 0.60 for all domains (exception of Jaundice 0.38), and all test-retest reliability coefficients were greater than 0.80. Four out of eight domains had statistically significant changes with effect size standardized response mean (SRM) ranging from 0.31 to 0.73. The Simplified Chinese version of QLQ-HCC18 demonstrates good validity, reliability, and responsiveness.
authors.affiliation: a School of Public Health and Tropical Medicine , Southern Medical University , Guanghzou , China.|b School of Public Health , Guangdong Medical University , Dongguan , China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Yang
authors.affiliation: c School of Humanities and Management, Research Center on Quality of Life and Applied Psychology , Guangdong Medical University , Dongguan , China.
authors.forename: Chonghua
authors.initials: C
authors.lastname: Wan
authors.affiliation: d School of Public Health , Kunming Medical University , Kunming , Yunnan , China.
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.affiliation: e Yunnan Tumor Hospital , Kunming , China.
authors.forename: Yingli
authors.initials: Y
authors.lastname: Cun
authors.affiliation: d School of Public Health , Kunming Medical University , Kunming , Yunnan , China.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Meng
authors.affiliation: b School of Public Health , Guangdong Medical University , Dongguan , China.
authors.forename: Yuanlin
authors.initials: Y
authors.lastname: Ding
authors.affiliation: a School of Public Health and Tropical Medicine , Southern Medical University , Guanghzou , China.
authors.forename: Pingyan
authors.initials: P
authors.lastname: Chen
mesh_terms: D000328:Adult; D044466:Asian People; D006528:Carcinoma, Hepatocellular / Q000523:psychology*; D002681:China; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires
keywords: FACT-Hep; Hepatocellular carcinoma; Multi-trait scaling analysis; Psychometric properties; QLQ-HCC18; Quality of life; Standardized response mean