title: Fabrication and durable antibacterial properties of electrospun chitosan nanofibers with silver nanoparticles.
abstract: Non-precipitation chitosan/silver nanoparticles (AgNPs) in 1% acetic acid aqueous solution was prepared from chitosan colloidal gel with various contents of silver nitrate via electron beam irradiation (EBI). Electrospun chitosan-based nanofibers decorated with AgNPs were successfully performed by blending poly(vinyl alcohol). The morphology of as-prepared nanofibers and the size of AgNPs in the nanofibers were investigated by field emission scanning electron microscopy (FESEM) and transmission electron microscopy (TEM). The presence of AgNPs in as-obtained nanofibers was also confirmed by ultraviolet-visible spectroscopy (UV), Fourier transform infrared (FT-IR) spectroscopy, EDX spectrum and metal mapping. Silver ion release behavior indicated that these hybrid nanofibers continually release adequate silver to exhibit antibacterial activity over 16 days. These biocomposite nanofibers showed pronounced antibacterial activity against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli).
authors.affiliation: Department of BIN Fusion Technology, Chonbuk National University, Jeonju 561-756, Republic of Korea.
authors.forename: Yanan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of BIN Fusion Technology, Chonbuk National University, Jeonju 561-756, Republic of Korea.
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Bionanosystem Engineering, Chonbuk National University, Jeonju 561-756, Republic of Korea.
authors.forename: Nina
authors.initials: N
authors.lastname: Liao
authors.affiliation: Department of BIN Fusion Technology, Chonbuk National University, Jeonju 561-756, Republic of Korea.
authors.forename: Fuhai
authors.initials: F
authors.lastname: Cui
authors.affiliation: Department of Organic Materials and Fiber Engineering, Chonbuk National University, Jeonju 561-756, Republic of Korea. Electronic address: wonderfulmira@jbnu.ac.kr.
authors.forename: Mira
authors.initials: M
authors.lastname: Park
authors.affiliation: Department of BIN Fusion Technology, Chonbuk National University, Jeonju 561-756, Republic of Korea. Electronic address: khy@jbnu.ac.kr.
authors.forename: Hak-Yong
authors.initials: HY
authors.lastname: Kim
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D002414:Cations, Monovalent; D048271:Chitosan / Q000737:chemistry*; D052978:Disk Diffusion Antimicrobial Tests; D055664:Electrochemical Techniques; D004583:Electrons; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D005782:Gels; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D055616:Microtechnology; D057139:Nanofibers / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D011142:Polyvinyl Alcohol / Q000737:chemistry; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development
chemical_list: D000900:Anti-Bacterial Agents; D002414:Cations, Monovalent; D005782:Gels; D012834:Silver; D011142:Polyvinyl Alcohol; D048271:Chitosan
keywords: Antibacterial nanofibers; Chitosan; Electrospinning; Silver nanoparticles