title: [Comparing the Application of Hema-Obs RSS to 250 Pregnancies from Obstetrics/Hematology Consultation in Centro Hospitalar São João, Portugal with the Application of Galit Sarig RSS to 90 Pregnancies from Rambam Health Care Campus, Israel].
abstract: BACKGROUND
  Pregnant women with thromboembolic diseases, previous thrombotic episodes or thrombophilia family history were supervised in a multidisciplinary Obstetrics/ Hematology consultation in Centro Hospitalar São João EPE, Porto, Portugal. For the evaluation and medication of these women, a risk stratification scale was used.
  
  
  OBJECTIVE
  The aim of this study was to validate a Risk Stratification Scale and thromboprophylaxis protocol by means of comparing it with a similar scale, developed and published by Sarig.
  
  
  METHODS
  We have compared: The distribution, by risk groups, obtained through the application of the two scales on pregnant women followed at Centro Hospitalar São João, Porto, Portugal, consultation; the sensibility and specificity for each one of the scales (DeLong scale, applied to Receiver Operating Characteristic) curves; the outcomes in pregnancies followed in Hospital São João, Porto, PortugalResults: According to our Hema-Obs risk stratification scale, 29% were allocated to low-risk, 47% to high-risk and 24% to very-high-risk groups. According to Galit Sarig risk stratification scale, 24% were considered low-risk, 53% moderate, 16% high-risk and 7% as very high-risk group. In our study we observed 9% of spontaneous abortions, in comparison with 18% in the Galit Sarig cohort. From the application of Receiver Operating Characteristic curve to both risk stratification scales, the results of the calculated areas were 58,8% to our Hema-Obs risk stratification scale and 38,7% to Galit Sarig risk stratification scale, with a Delong test significancie of p = 0.0006.
  
  
  CONCLUSIONS
  We concluded that Hema-Obs risk stratification scale is an effective support for clinical monitoring of therapeutic strategies.
authors.affiliation: Serviço de Imuno-Hemoterapia. Centro Hospitalar de S. João. Porto. Portugal.
authors.forename: Ana
authors.initials: A
authors.lastname: Salselas
authors.affiliation: Serviço de Ginecologia e Obstetrícia. Centro Hospitalar de S. João. Porto. Portugal.
authors.forename: Inês
authors.initials: I
authors.lastname: Pestana
authors.affiliation: Serviço de Imuno-Hemoterapia. Centro Hospitalar de S. João. Porto. Portugal.
authors.forename: Francisco
authors.initials: F
authors.lastname: Bischoff
authors.affiliation: Serviço de Ginecologia e Obstetrícia. Centro Hospitalar de S. João. Porto. Portugal.
authors.forename: Mariana
authors.initials: M
authors.lastname: Guimarães
authors.affiliation: Serviço de Hematologia Clínica. Centro Hospitalar de S. João. Porto. Portugal.
authors.forename: Joaquim Aguiar
authors.initials: JA
authors.lastname: Andrade
mesh_terms: D000328:Adult; D002985:Clinical Protocols; D005260:Female; D006405:Hematology; D006761:Hospitals; D006801:Humans; D007557:Israel; D009774:Obstetrics; D011174:Portugal; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis* / Q000517:prevention & control*; D018570:Risk Assessment; D019851:Thrombophilia / Q000517:prevention & control*