title: DNA-functionalized upconversion nanoparticles as biosensors for rapid, sensitive, and selective detection of Hg(2+) in complex matrices.
abstract: We have developed a facile one-step approach to make hydrophilic and DNA-functionalizable upconversion nanoparticles (UCNPs), which are used to act as a biosensor for determining Hg(2+) in complex matrices. The proposed approach is simple and exhibits low background interference, high sensitivity and rapid response.
authors.affiliation: State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, P. R. China. xiachu@hnu.edu.cn.
authors.forename: Li-Jiao
authors.initials: LJ
authors.lastname: Huang
authors.forename: Ru-Qin
authors.initials: RQ
authors.lastname: Yu
authors.forename: Xia
authors.initials: X
authors.lastname: Chu
mesh_terms: D015374:Biosensing Techniques / Q000191:economics / Q000379:methods*; D002413:Cations, Divalent / Q000032:analysis / Q000652:urine; D004247:DNA / Q000737:chemistry*; D060766:Drinking Water / Q000032:analysis; D006801:Humans; D057230:Limit of Detection; D049449:Luminescence; D008628:Mercury / Q000032:analysis* / Q000652:urine*; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D045483:Rivers / Q000737:chemistry; D013050:Spectrometry, Fluorescence / Q000379:methods; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000652:urine*
chemical_list: D002413:Cations, Divalent; D060766:Drinking Water; D014874:Water Pollutants, Chemical; D004247:DNA; D008628:Mercury