title: Management of myelofibrosis during pregnancy: a case report.
abstract: BACKGROUND
  Primary myelofibrosis (PMF) is a clonal myeloproliferative neoplasm that occurs most commonly in the decade six of life and it is very rare in the young persons.
  
  
  METHODS
  We reported a 28-year-old female patient with primary myelofibrosis who had a normal pregnancy and delivery in the week 40 of pregnancy without any complications. Two years before the diagnosis of PMF she had normal pregnancy. The patient was treated with interferon-alpha and low dose aspirin during the whole pregnancy and with low-molecular-weight heparin a week before delivery and 6 weeks after. The patient had no complications during pregnancy. She delivered in term with healthy, normal baby weight.
  
  
  CONCLUSIONS
  Decision about treatment strategy of pregnancy associated hematologic malignancies should be made for each patient individually.
authors.forename: Radmila
authors.initials: R
authors.lastname: Zivković
authors.forename: Olivera
authors.initials: O
authors.lastname: Marković
authors.forename: Dragomir
authors.initials: D
authors.lastname: Marisavljević
authors.forename: Tatjana
authors.initials: T
authors.lastname: Terzić
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Tukić
mesh_terms: D000328:Adult; D001241:Aspirin / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage*; D006801:Humans; D007155:Immunologic Factors / Q000008:administration & dosage; D016898:Interferon-alpha / Q000008:administration & dosage*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis / Q000188:drug therapy; D011256:Pregnancy Outcome; D055728:Primary Myelofibrosis / Q000175:diagnosis / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D007155:Immunologic Factors; D016898:Interferon-alpha; D001241:Aspirin