title: Sequential Michael Addition and Enamine-Promoted Inverse Electron Demanding Diels-Alder Reaction upon 3-Vinyl-1,2,4-triazine Platforms.
abstract: An original one-pot Michael addition-ihDA/rDA sequence was achieved from 3-vinyl-1,2,4-triazine platforms used as unprecedented Michael acceptors. This sequence provides a novel access to functionalized [2,3]-fused pyridine derivatives via a unique enamine promoted intramolecular ihDA reaction of 1,2,4-triazine intermediates.
authors.affiliation: †Université d'Orléans, CNRS, ICOA, UMR 7311, 45067 Orléans, France.
authors.forename: Magali
authors.initials: M
authors.lastname: Lorion
authors.affiliation: †Université d'Orléans, CNRS, ICOA, UMR 7311, 45067 Orléans, France.
authors.forename: Gérald
authors.initials: G
authors.lastname: Guillaumet
authors.affiliation: ‡Normandie Univ, COBRA, UMR 6014 et FR 3038; Univ Rouen, INSA Rouen; CNRS, IRCOF, 1 rue Tesnière, 76821 Mont Saint Aignan cedex, France.
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Brière
authors.affiliation: †Université d'Orléans, CNRS, ICOA, UMR 7311, 45067 Orléans, France.
authors.forename: Franck
authors.initials: F
authors.lastname: Suzenet
mesh_terms: D002384:Catalysis; D061565:Cycloaddition Reaction / Q000379:methods*; D004583:Electrons; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*; D014227:Triazines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: C000602951:3-vinyl-1,2,4-triazine; D011725:Pyridines; D014227:Triazines; C023666:pyridine