title: Reprint of: Aspirin use and early age-related macular degeneration: a meta-analysis.
abstract: OBJECTIVE
  The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD).
  
  
  METHODS
  A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark).
  
  
  RESULTS
  The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09-1.88).
  
  
  CONCLUSIONS
  There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation.
authors.affiliation: South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
authors.forename: Shyalle K
authors.initials: SK
authors.lastname: Kahawita
authors.affiliation: South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia. Electronic address: s.kahawita@gmail.com.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Casson