title: Platelet function parameters in management of hepatic hydatid disease: a case-controlled study.
abstract: OBJECTIVE
  To evaluate platelet function in patients with a history of surgical treatment for hepatic hydatid disease (HD).
  
  
  METHODS
  This retrospective case-controlled study was performed in a state hospital in Turkey from January 2009 to November 2013. The patients were divided into two groups: those evaluated in the preoperative period (Group 1) and those evaluated in the postoperative period (Group 2). The patient groups were compared with a control group (Group 3). All three groups were evaluated using laboratory records from day 1 of the preoperative period and day 30 of the postoperative period. The haematocrit level (HTC), platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), and percentage of eosinophils (EOS) were compared among the groups.
  
  
  RESULTS
  Fifty-three patients who had undergone surgical treatment of hepatic HD and 55 healthy controls were included in the study. The mean follow-up time for all patients was 45 (14-70) months. The patients comprised 33 (62%) females and 20 (38%) males. The control group comprised 37 (67%) females and 18 (33%) males. The median age of the patients was 48 (19-78) years, while that of the control group was 42 (16-64) years. No significant differences in the HTC, PLT, or EOS were present among the groups. The MPV and PDW indicated that platelet function was significantly different between Group 1 and Groups 2 and 3. Additionally, nine patients had undergone previous surgical treatment for HD. In a separate long-term follow-up, these patients exhibited no statistically significant differences in MPV or PDW between the preoperative and postoperative periods.
  
  
  CONCLUSIONS
  MPV and PDW can be used in the initial follow-up of patients with hepatic HD, but have limited use in long-term follow-up.
authors.affiliation: Department of Surgery, Ataturk State Hospital Antalya 07040, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Dinc
authors.affiliation: Department of Biology, Pamukkale University, Faculty of Arts and Sciences Denizli 20070, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Dusen
authors.affiliation: Department of Surgery, Diyarbakir Training and Research Hospital Diyarbakir 21010, Turkey.
authors.forename: Nurettin
authors.initials: N
authors.lastname: Ay
authors.affiliation: Department of Emergency, Isparta State Hospital Isparta 32100, Turkey.
authors.forename: Selcan Enver
authors.initials: SE
authors.lastname: Dinc
authors.affiliation: Department of Surgery, Antalya Training and Research Hospital Diyarbakir 07050, Turkey.
authors.forename: Burhan
authors.initials: B
authors.lastname: Mayir
authors.affiliation: Department of Surgery, Antalya Training and Research Hospital Diyarbakir 07050, Turkey.
authors.forename: Umut Riza
authors.initials: UR
authors.lastname: Gunduz
authors.affiliation: Department of Surgery, Ataturk State Hospital Antalya 07040, Turkey.
authors.forename: Ozgur Cem
authors.initials: OC
authors.lastname: Musri
authors.affiliation: Department of Gastroenterology, Ataturk State Hospital Antalya 07040, Turkey.
authors.forename: Bilge
authors.initials: B
authors.lastname: Bas
authors.affiliation: Department of Surgery, Antalya Training and Research Hospital Diyarbakir 07050, Turkey.
authors.forename: Ugur
authors.initials: U
authors.lastname: Dogan
authors.affiliation: Department of Emergency, Denizli State Hospital Denizli 20010, Turkey.
authors.forename: Alten
authors.initials: A
authors.lastname: Oskay
keywords: Hepatic hydatid cysts; disease management; platelet function test