title: Topical Agents and Dressings for Pilonidal Sinus Wound Healing by Secondary Intention: A Scoping Review.
abstract: Pilonidal disease (PD) is a chronic and debilitating condition. The overall aim of the scoping review is to map and summarize a wide range of evidence to examine which topical agent or dressing is effective in promoting pilonidal wound healing by secondary intention. Review of this cumulative body of evidence will inform care and guide dressing selection for PD related wounds and delineate future research priorities based on identified knowledge gaps and clinical practice issues. Overall, there is some evidence to suggest that topical applications of hydrogel, silver, honey, zinc, selected foam materials, negative pressure wound therapy, platelet rich plasma, and plant extracts may promote wound healing. Topical treatment using polyhexamethylene biguanide and silver may be beneficial in reducing bacterial burden. Finally, silver, honey, and hydrocolloid dressings may help alleviate wound related pain. However, evidence remains insufficient in light of methodological limitations and biases of the studies.
authors.affiliation: School of Nursing Queen's University, Kingston, Canada / West Park Healthcare Center, Toronto, Canada.
authors.forename: Kevin Y
authors.initials: KY
authors.lastname: Woo
authors.affiliation: School of Nursing The Hong Kong Polytechnic University, Hong Kong, People's Republic of China.
authors.forename: Enid Wai-Yung
authors.initials: EW
authors.lastname: Kwong
authors.affiliation: Queen's University, Kingston, Canada.
authors.forename: Carolina
authors.initials: C
authors.lastname: Jimenez
authors.affiliation: Skin and Wound Care Halton Healthcare Services, Oakville, Ontario.
authors.forename: Richard
authors.initials: R
authors.lastname: Bishop
mesh_terms: D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use*; D001458:Bandages; D006722:Honey; D006801:Humans; D020100:Hydrogels; D054843:Negative-Pressure Wound Therapy; D010864:Pilonidal Sinus / Q000628:therapy*; D012834:Silver; D014945:Wound Healing
chemical_list: D000900:Anti-Bacterial Agents; D020100:Hydrogels; D012834:Silver