title: COMPARISON OF TWO α2-ADRENERGIC AGONISTS ON URINE CONTAMINATION OF SEMEN COLLECTED BY ELECTROEJACULATION IN CAPTIVE AND SEMI-FREE-RANGING CHEETAH (ACINONYX JUBATUS).
abstract: Alpha2-adrenergic agonists are used to immobilize many veterinary species, but use has been infrequently linked to urine contamination of semen collected via electroejaculation. The objective of the study was to compare the α2-agonists medetomidine and dexmedetomidine on urine contamination of semen in anesthetized cheetahs (Acinonyx jubatus) during electroejaculation procedures. From 2009-2012, a retrospective medical record review revealed 21 anesthesia events in 12 adult male cheetahs. Animals were immobilized with combinations of Telazol® (2.33±0.43 mg/kg) and ketamine (2.38±1 mg/kg); Telazol (1.17±0.14 mg/kg), ketamine (1.17±0.14 mg/kg), and medetomidine (0.012±0.0017 mg/kg); or Telazol (1.59±0.1 mg/kg), ketamine (1.59±0.1 mg/kg) and dexmedetomidine (0.01±0.001 mg/kg). Semen was successfully collected in all animals; four animals anesthetized with medetomidine had urine contamination (P=0.037). Medetomidine may contribute to urine contamination; however, further investigation is needed to determine significance in cheetahs.
authors.forename: Judilee C
authors.initials: JC
authors.lastname: Marrow
authors.forename: Margarita
authors.initials: M
authors.lastname: Woc-Colburn
authors.forename: Lee-Ann C
authors.initials: LA
authors.lastname: Hayek
authors.forename: Laurie
authors.initials: L
authors.lastname: Marker
authors.forename: Suzan
authors.initials: S
authors.lastname: Murray
mesh_terms: D002612:Acinonyx / Q000502:physiology* / Q000652:urine; D058647:Adrenergic alpha-2 Receptor Agonists / Q000009:adverse effects / Q000494:pharmacology; D000818:Animals; D000836:Animals, Zoo; D020927:Dexmedetomidine / Q000009:adverse effects / Q000494:pharmacology*; D004542:Ejaculation / Q000502:physiology*; D004558:Electric Stimulation; D007103:Immobilization / Q000379:methods / Q000662:veterinary; D008297:Male; D020926:Medetomidine / Q000009:adverse effects / Q000494:pharmacology*; D012661:Semen / Q000502:physiology*
chemical_list: D058647:Adrenergic alpha-2 Receptor Agonists; D020927:Dexmedetomidine; D020926:Medetomidine
keywords: Acinonyx jubatus; cheetah; electroejaculation; semen; urine contamination; α2-adrenergic agonist