title: [Neurological symptoms due to Mycoplasma pneumoniae infection in nine children].
abstract: Mycoplasma pneumoniae infection is common in children. Extrapulmonary symptoms usually reveal as neurological symptoms, mainly as encephalitis with significant morbidity and mortality. Various other neurological presentations have also been reported. We describe a cohort of nine children with neurological manifestations due to M. pneumoniae infection, including five cases of encephalitis, one of polyradiculoneuritis, one of ophthalmoplegia, one of optic neuritis, and one of myositis. Progression was variable from ad integrum recovery to severe brain damage. Diagnosis is usually confirmed by PCR and/or serological follow-up, but the latter is still insufficiently used in practice to systematically affirm the diagnosis. Therapeutic management is not clearly defined and long-term progression can be uncertain despite early antibiotic and/or anti-inflammatory treatments.
authors.affiliation: Service des urgences pédiatriques, hôpital Estaing, CHU de Clermont-Ferrand, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, France.
authors.forename: P
authors.initials: P
authors.lastname: Roussel
authors.affiliation: Service de neurologie pédiatrique, hôpital Femme-Mère-Enfant, hospices civils de Lyon, 59, boulevard Pinel, 69677 Bron, France.
authors.forename: A-L
authors.initials: AL
authors.lastname: Poulat
authors.affiliation: Service de bactériologie, mycologie et parasitologie, hôpital Gabriel-Montpied, CHU de Clermont-Ferrand, 58, rue Montalembert, 63003 Clermont-Ferrand cedex 1, France.
authors.forename: J-P
authors.initials: JP
authors.lastname: Romaszko
authors.affiliation: Service des urgences pédiatriques, hôpital Estaing, CHU de Clermont-Ferrand, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, France.
authors.forename: A
authors.initials: A
authors.lastname: Labbé
authors.affiliation: Service des urgences pédiatriques, hôpital Estaing, CHU de Clermont-Ferrand, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, France. Electronic address: csarret@chu-clermontferrand.fr.
authors.forename: C
authors.initials: C
authors.lastname: Sarret
mesh_terms: D000293:Adolescent; D002648:Child; D004660:Encephalitis / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D009422:Nervous System Diseases / Q000382:microbiology*; D011019:Pneumonia, Mycoplasma / Q000150:complications* / Q000175:diagnosis*; D012189:Retrospective Studies