title: Peters anomaly in cri-du-chat syndrome.
abstract: The cri-du-chat syndrome is a rare genetic disorder caused by deletions in the short arm of chromosome 5. It presents with a distinctive catlike high-pitched cry, psychomotor delays, microcephaly, craniofacial abnormalities, and, in many cases, ocular findings. We report the first child with cri-du-chat and the findings of unilateral corneal staphyloma due to Peters anomaly and retinal dysplasia.
authors.affiliation: Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.
authors.forename: William C
authors.initials: WC
authors.lastname: Hope
authors.affiliation: Pediatric Ophthalmology and Ocular Genetics, Philadelphia, Pennsylvania.
authors.forename: Jose A
authors.initials: JA
authors.lastname: Cordovez
authors.affiliation: Pediatric Ophthalmology and Ocular Genetics, Philadelphia, Pennsylvania.
authors.forename: Jenina E
authors.initials: JE
authors.lastname: Capasso
authors.affiliation: Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania; Cornea Service, Philadelphia, Pennsylvania.
authors.forename: Kristin M
authors.initials: KM
authors.lastname: Hammersmith
authors.affiliation: Cornea Service, Philadelphia, Pennsylvania; Pathology, Wills Eye Hospital, Philadelphia, Pennsylvania.
authors.forename: Ralph C
authors.initials: RC
authors.lastname: Eagle
authors.affiliation: Children's Hospital of the King's Daughters, Norfolk, Virginia.
authors.forename: Joel
authors.initials: J
authors.lastname: Lall-Trail
authors.affiliation: Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania; Children's Hospital of the King's Daughters, Norfolk, Virginia. Electronic address: alevin@willseye.org.
authors.forename: Alex V
authors.initials: AV
authors.lastname: Levin
mesh_terms: D000869:Anterior Eye Segment / Q000002:abnormalities*; D002872:Chromosome Deletion; D002895:Chromosomes, Human, Pair 5 / Q000235:genetics; D003315:Cornea / Q000473:pathology; D003316:Corneal Diseases / Q000175:diagnosis / Q000209:etiology*; D003318:Corneal Opacity / Q000150:complications* / Q000175:diagnosis; D003410:Cri-du-Chat Syndrome / Q000150:complications* / Q000175:diagnosis; D002658:Developmental Disabilities; D005124:Eye Abnormalities / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D008831:Microcephaly / Q000175:diagnosis / Q000209:etiology; D033401:Microscopy, Acoustic; D015792:Retinal Dysplasia / Q000175:diagnosis / Q000209:etiology*