title: Comparison of Percutaneous Cementoplasty with and Without Interventional Internal Fixation for Impending Malignant Pathological Fracture of the Proximal Femur.
abstract: OBJECTIVE
  To compare the efficacy of percutaneous cementoplasty (PCP) with and without interventional internal fixation (IIF) on malignant impending pathological fracture of proximal femur.
  
  
  METHODS
  A total of 40 patients with malignant impending pathological fracture of proximal femur were selected for PCP and IIF (n = 19, group A) or PCP alone (n = 21, group B) in this non-randomized prospective study. Bone puncture needles were inserted into the proximal femur, followed by sequential installation of the modified trocar inner needles through the puncture needle sheath. Then, 15-45 ml cement was injected into the femur lesion.
  
  
  RESULTS
  The overall excellent and good pain relief rate during follow-ups were significantly higher in group A than that in group B (89 vs. 57 %, P = 0.034). The average change of VAS, ODI, KPS, and EFES in group A were significantly higher than those in group B at 1-, 3-, 6-month, 1-year (P < 0.05). Meanwhile, The stability of the treated femur was significantly higher in group A than that in group B (P < 0.05).
  
  
  CONCLUSIONS
  PCP and IIF were not only a safe and effective procedure, but resulted in greater pain relief, bone consolidation, and also reduced the risk of fracture than the currently recommended approach of PCP done on malignant proximal femoral tumor.
authors.affiliation: Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600 Yishan Road, Shanghai, 200233, China. ddqinghua-tian@163.com.
authors.forename: Qing-Hua
authors.initials: QH
authors.lastname: Tian
authors.affiliation: Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600 Yishan Road, Shanghai, 200233, China. tianhechengjian@163.com.
authors.forename: Cheng-Jian
authors.initials: CJ
authors.lastname: He
authors.affiliation: Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600 Yishan Road, Shanghai, 200233, China. 649514608@qq.com.
authors.forename: Chun-Gen
authors.initials: CG
authors.lastname: Wu
authors.affiliation: Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600 Yishan Road, Shanghai, 200233, China. tianliyongdong@163.com.
authors.forename: Yong-Dong
authors.initials: YD
authors.lastname: Li
authors.affiliation: Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600 Yishan Road, Shanghai, 200233, China. tianyifenggu@163.com.
authors.forename: Yi-Feng
authors.initials: YF
authors.lastname: Gu
authors.affiliation: Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600 Yishan Road, Shanghai, 200233, China. tianandwangtao@163.com.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.affiliation: Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600 Yishan Road, Shanghai, 200233, China. tianxiaoquanping@163.com.
authors.forename: Quan-Ping
authors.initials: QP
authors.lastname: Xiao
authors.affiliation: Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600 Yishan Road, Shanghai, 200233, China. tianminghuali@163.com.
authors.forename: Ming-Hua
authors.initials: MH
authors.lastname: Li
mesh_terms: D060826:Cementoplasty / Q000379:methods*; D005260:Female; D005264:Femoral Fractures / Q000517:prevention & control*; D005266:Femoral Neoplasms / Q000150:complications*; D005593:Fracture Fixation, Internal / Q000379:methods*; D005598:Fractures, Spontaneous / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome
keywords: Interventional internal fixation; Pathological fracture; Percutaneous cementoplasty; Proximal femur