title: Host cell targets for African swine fever virus.
abstract: Viruses are strict intracellular pathogens that require the cellular environment to complete a successful infection. Among them, African swine fever virus (ASFV) is an evolutionary ancient DNA virus, endemic in Africa, which is nowadays causing an emergent disease in Europe with a potential high economic impact in the pig industry. It is well known that host-cell components are critical crossroads mapping the virus path for a productive infection, some of them at the endocytic pathway. Considering that ASFV infectious cycle strongly relies in several factors from the host cell, the study of virus-host interactions remains crucial as they will reveal the obstacles, routes and tracks, hints and the target waypoint in the virus journey to destination.
authors.affiliation: Department of Biotechnology, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28040 Madrid, Spain. Electronic address: raquel.munoz@mssm.edu.
authors.forename: Raquel
authors.initials: R
authors.lastname: Muñoz-Moreno
authors.affiliation: Department of Biotechnology, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28040 Madrid, Spain. Electronic address: galindo@inia.es.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Galindo
authors.affiliation: Department of Biotechnology, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28040 Madrid, Spain. Electronic address: cuesta.miguel@inia.es.
authors.forename: Miguel Ángel
authors.initials: MÁ
authors.lastname: Cuesta-Geijo
authors.affiliation: Department of Biotechnology, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28040 Madrid, Spain. Electronic address: barrado.lucia@inia.es.
authors.forename: Lucía
authors.initials: L
authors.lastname: Barrado-Gil
authors.affiliation: Department of Biotechnology, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), 28040 Madrid, Spain. Electronic address: calonso@inia.es.
authors.forename: Covadonga
authors.initials: C
authors.lastname: Alonso
mesh_terms: D000358:African Swine Fever Virus / Q000502:physiology*; D000818:Animals; D054884:Host-Pathogen Interactions; D013552:Swine; D014779:Virus Replication
keywords: African swine fever virus; Aggresomes; BAG3; Cholesterol; Endocytosis; HDAC6; Host cell targets; Phosphatidylinositol phosphates and kinases; Viral factories; Virus entry