title: Myelodysplastic Syndrome with 6q Deletion as the Sole Chromosome Abnormality in an Iranian Patient: A Case Report with Review of Literature.
abstract: The myelodysplastic syndrome (MDS) is a highly heterogenous disorder and karyotype analysis is helpful for diagnostic and prognostic estimation. Deletion in long arm chromosome 6 (6q del) as a sole abnormality is a rare event in MDS. This is the first case report of del (6q) as the only observed diagnostic change in Iran. We also reviewed the literature of this cytogenetic lesion.
authors.affiliation: 1. Dept. of Hematology, Iranian Blood Transfusion Organization , Tehran, Iran.
authors.forename: Shirin
authors.initials: S
authors.lastname: Ferdowsi
authors.affiliation: 2. Dept. of Molecular Genetics, Cancer Research Center, Cancer Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences , Tehran, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Shirkoohi
authors.affiliation: 3. Dept. of Hematology-Oncology and BMT Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences , Tehran, Iran.
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Toogeh
keywords: Deletion 6q; Iran; Myelodysplastic syndrome