title: Geometrical and mechanical factors that influence slipped capital femoral epiphysis: a finite element study.
abstract: Slipped capital femoral epiphysis (SCFE) is an orthopedic pathology in which damage of the growth plate leads to the anterosuperior displacement of the femoral body in respect to the femoral head. Despite being a widely studied disease, its etiology is still unknown. This study was carried out to determine the influence of the physeal-diaphysis angle, body mass, the presence of the perichondrial ring, the type of physical activity, and physeal thickness on SCFE. For this purpose, a finite element analysis of the hip joint and the femur-physis interface was carried out. With the computational model, the Von Mises stresses along the growth plate were calculated and subsequently analyzed statistically to find their correlation with the studied factors. It was found that body mass, the type of physical activity, and the presence of the perichondrial ring had more statistical relevance for the physeal stresses than the physeal-diaphysis angle and the physeal thickness. Thus, our work suggests that changes in growth plate inclination and thickness do not influence the etiology of SCFE.
authors.affiliation: aBiomimetic Laboratory, Biotechnology Institute bModelling and Numerical Methods Group, Department of Mechanical and Mechatronics Engineering cDepartment of Orthopedic Surgery and Traumatology, Universidad Nacional de Colombia dDepartment of Investigations, University of America, Bogotá, Colombia.
authors.forename: Hector A
authors.initials: HA
authors.lastname: Castro-Abril
authors.forename: Fernando
authors.initials: F
authors.lastname: Galván
authors.forename: Diego A
authors.initials: DA
authors.lastname: Garzón-Alvarado
mesh_terms: D000704:Analysis of Variance; D001696:Biomechanical Phenomena; D001835:Body Weight; D002648:Child; D004838:Epiphyses / Q000033:anatomy & histology / Q000502:physiology; D005270:Femur Head / Q000033:anatomy & histology / Q000502:physiology; D020342:Finite Element Analysis; D006132:Growth Plate / Q000033:anatomy & histology / Q000502:physiology; D006621:Hip Joint / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology; D006801:Humans; D008297:Male; D009043:Motor Activity; D012307:Risk Factors; D060048:Slipped Capital Femoral Epiphyses / Q000209:etiology*; D014057:Tomography, X-Ray Computed