title: Update in outpatient general internal medicine: practice-changing evidence published in 2014.
abstract: The practice of outpatient general internal medicine requires a diverse and evolving knowledge base. General internists must identify practice-changing shifts in the literature and reflect on their impact. Accordingly, we conducted a review of practice-changing articles published in outpatient general internal medicine in 2014. To identify high-quality, clinically relevant publications, we reviewed all titles and abstracts published in the following primary data sources in 2014: New England Journal of Medicine, Journal of the American Medical Association (JAMA), Annals of Internal Medicine, JAMA Internal Medicine, and the Cochrane Database of Systematic Reviews. All 2014 primary data summaries from Journal Watch-General Internal Medicine and ACP JournalWise also were reviewed. The authors used a modified Delphi method to reach consensus on inclusion of 8 articles using the following criteria: clinical relevance to outpatient internal medicine, potential for practice change, and strength of evidence. Clusters of important articles around one clinical question were considered as a single-candidate series. The article merits were debated until consensus was reached on the final 8, spanning a variety of topics commonly encountered in outpatient general internal medicine.
authors.affiliation: Division of General Internal Medicine, Department of Medicine, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minn. Electronic address: sundsted.karna@mayo.edu.
authors.forename: Karna K
authors.initials: KK
authors.lastname: Sundsted
authors.affiliation: Division of Primary Care Internal Medicine, Department of Medicine, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minn.
authors.forename: Mark L
authors.initials: ML
authors.lastname: Wieland
authors.affiliation: Division of General Internal Medicine, Department of Medicine, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minn.
authors.forename: Jason H
authors.initials: JH
authors.lastname: Szostek
authors.affiliation: Division of Primary Care Internal Medicine, Department of Medicine, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minn.
authors.forename: Jason A
authors.initials: JA
authors.lastname: Post
authors.affiliation: Division of General Internal Medicine, Department of Medicine, Mayo Clinic and Mayo Clinic College of Medicine, Rochester, Minn.
authors.forename: Karen F
authors.initials: KF
authors.lastname: Mauck
mesh_terms: D000553:Ambulatory Care / Q000379:methods*; D019317:Evidence-Based Medicine; D058006:General Practice / Q000379:methods*; D006801:Humans; D007388:Internal Medicine / Q000379:methods*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D014481:United States
keywords: ACE inhibitor; Alcohol use disorder; Alzheimer disease; Cancer screening; General internal medicine; Hepatitis C; Literature update; Lung cancer; Novel anticoagulant; Outpatient; Statin; Stool DNA test