title: Preparation and characterization of the graft copolymer of chitosan with poly[rosin-(2-acryloyloxy)ethyl ester].
abstract: Graft copolymerization of rosin-(2-acryloyloxy)ethyl ester (RAEE) onto chitosan (Cts) was carried out under microwave irradiation using potassium persulfate as an initiator. The structures, morphology, and thermal properties of the Cts graft copolymer (Cts-g-PRAEE) were characterized by means of FT-IR, XRD, SEM, and TG. Also, Cts and Cts-g-PRAEE copolymer were used as carriers of fenoprofen calcium (FC), and their controlled release behavior in artificial intestinal juice were studied. The results show that the rate of release of fenoprofen calcium from the carrier of Cts-g-PRAEE copolymer becomes very slower than that of Cts in artificial intestinal juice.
authors.affiliation: School of Chemistry and Chemical Engineering, Guangxi University, No. 100, Daxue Road, Nanning, Guangxi 530004, PR China. Electronic address: wgduan@gxu.edu.cn.
authors.forename: Wengui
authors.initials: W
authors.lastname: Duan
authors.affiliation: School of Chemistry and Chemical Engineering, Guangxi University, No. 100, Daxue Road, Nanning, Guangxi 530004, PR China.
authors.forename: Chunhong
authors.initials: C
authors.lastname: Chen
authors.affiliation: School of Chemistry and Chemical Engineering, Guangxi University, No. 100, Daxue Road, Nanning, Guangxi 530004, PR China. Electronic address: jianglinbin@126.com.
authors.forename: Linbin
authors.initials: L
authors.lastname: Jiang
authors.affiliation: School of Chemistry and Chemical Engineering, Guangxi University, No. 100, Daxue Road, Nanning, Guangxi 530004, PR China. Electronic address: lighuas@gxu.edu.com.
authors.forename: Guang Hua
authors.initials: GH
authors.lastname: Li
keywords: Chitosan; Drug release; Graft copolymer; Microwave; Rosin-(2-acryloyloxy)ethyl ester