title: Fluconazole susceptibility of 3,056 clinical isolates of Candida species from 2005 to 2009 in a tertiary-care hospital.
abstract: In recent years, Candida infections have been increasing significantly. This study was to investigate the distribution and fluconazole susceptibility of such infections. Totally, 3,056 clinical isolates were analysed, C. albicans was the most prevalent species from respiratory and vaginal specimens. However, non-albicans species constituted the majority of isolates from blood, urine, intensive care unit (ICU), organ transplant and burned patients. Similarly, Candida spp. from different specimens and clinical services had different degrees of susceptibility to fluconazole. Isolates from vagina and burned patients had the highest resistance rate, while all of the isolates from ascites and dermatological services were susceptible to fluconazole.
authors.forename: Y
authors.initials: Y
authors.lastname: Ying
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: S B
authors.initials: SB
authors.lastname: Huang
authors.forename: F D
authors.initials: FD
authors.lastname: Liu
authors.forename: J H
authors.initials: JH
authors.lastname: Liu
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: X F
authors.initials: XF
authors.lastname: Hu
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Zhang
authors.forename: X
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Medical Microbiology, School of Medicine, Nanchang University, Nanchang, People's Republic of China.
authors.forename: X T
authors.initials: XT
authors.lastname: Huang
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects* / Q000302:isolation & purification*; D002177:Candidiasis / Q000453:epidemiology / Q000382:microbiology*; D025141:Drug Resistance, Fungal; D015725:Fluconazole / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D062606:Tertiary Care Centers
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole