title: Narrow Band Imaging: A Tool for Endoscopic Examination of Patients With Laryngeal Papillomatosis.
abstract: OBJECTIVE
  Narrow band imaging (NBI) is supposed to be a technique for a better visualization of vessel structures in superficial tissue as it selects the wavelengths of hemoglobin. It was hypothesized that, in the regular follow-up examination of patients with recurrent laryngeal papillomatosis, NBI enables a better detection of laryngeal papillomatosis in contrast to normal white light endoscopy.
  
  
  METHODS
  Eleven patients, 10 with a known recurrent papillomatosis (8 with a relapse, 2 without) and 1 with a primary diagnosis of papillomatosis, were examined with normal white light and NBI endoscopy. Twenty-six video sequences (11 white, 11 NBI, 4 doubled for validity) were generated and randomly presented to 20 otolaryngologists who rated the videos in terms of lesions seen and number of lesions identified. Results were compared with the histopathologic findings of microlaryngoscopy.
  
  
  RESULTS
  Detection of papillomatosis and the correct number of lesions identified were more accurate with NBI than with normal white light endoscopy. There was a significantly higher probability of detecting laryngeal papillomata with NBI.
  
  
  CONCLUSIONS
  NBI endoscopy enables a more accurate detection of laryngeal papillomatosis than white light endoscopy.
authors.affiliation: Department of Otorhinolaryngology, University Hospital, Mainz, Germany sebastian.dippold@unimedizin-mainz.de.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Dippold
authors.affiliation: Department of Otorhinolaryngology, University Hospital, Freiburg, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Becker
authors.affiliation: Institute of Musicians' Medicine, University Hospital, Freiburg, Germany.
authors.forename: Manfred
authors.initials: M
authors.lastname: Nusseck
authors.affiliation: Institute of Musicians' Medicine, University Hospital, Freiburg, Germany.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Richter
authors.affiliation: Institute of Musicians' Medicine, University Hospital, Freiburg, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Echternach
mesh_terms: D000328:Adult; D057186:Comparative Effectiveness Research; D061827:Dimensional Measurement Accuracy; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D007828:Laryngoscopy / Q000379:methods*; D008297:Male; D018715:Microscopy, Video / Q000379:methods*; D062048:Narrow Band Imaging / Q000379:methods*; D010212:Papilloma / Q000473:pathology*
keywords: follow-up examination; laryngeal papillomatosis; narrow band imaging; white light endoscopy