title: [Tuberculosis of the female genital tract discovered during work-ups for infertility: the first two cases at the Fianarantsoa Teaching Hospital in Madagascar].
abstract: The rarity of genital tuberculosis and the non-specificity of its manifestations lead to delayed diagnosis and the need to treat this disease at an advanced stage. We report two cases observed and treated at the Fianarantsoa Teaching Hospital: two young women (aged 22 and 33 years) discovered during work-ups for primary infertility and secondary amenorrhea. The diagnosis was established by histological examination of granulomatous tissue with caseous necrosis, pathognomonic for tuberculous. Isolation of mycobacterium by inoculation on Lowenstein-Jensen medium and culture are not available in Fianarantsoa. Chemotherapy against tuberculosis is most often effective for the disease, but fertility is definitely compromised, even though in vitro fertilization is possible in some cases.
authors.affiliation: Université de Fianarantsoa, CHU Tambohobe Fianarantsoa, 00301 Fianarantsoa, Madagascar.
authors.forename: H
authors.initials: H
authors.lastname: Rakotomahenina
authors.affiliation: Université de Fianarantsoa, CHU Tambohobe Fianarantsoa, 00301 Fianarantsoa, Madagascar.
authors.forename: H A
authors.initials: HA
authors.lastname: Andrianampy
authors.affiliation: Université de Fianarantsoa, CHU Tambohobe Fianarantsoa, 00301 Fianarantsoa, Madagascar.
authors.forename: J L
authors.initials: JL
authors.lastname: Rakotoson
authors.affiliation: Université de Fianarantsoa, CHU Tambohobe Fianarantsoa, 00301 Fianarantsoa, Madagascar.
authors.forename: M
authors.initials: M
authors.lastname: Rabarijaona
authors.affiliation: Université d'Antananarivo, Madagascar.
authors.forename: G D
authors.initials: GD
authors.lastname: Solofomalala
authors.affiliation: CHU Bordeaux, France.
authors.forename: J L
authors.initials: JL
authors.lastname: Brun
mesh_terms: D000328:Adult; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D033162:Incidental Findings; D007247:Infertility, Female / Q000175:diagnosis; D008270:Madagascar; D014384:Tuberculosis, Female Genital / Q000175:diagnosis*; D055815:Young Adult
keywords: Madagascar; amenorrhea; genital tuberculosis; histology; infertility