title: Association between LAP Index (Lipid Accumulation Product) and metabolic profile in hospitalized patients.
abstract: BACKGROUND
  Lipid Accumulation Product (LAP) Index correlates to cardiovascular risk factors in general population but it has not been tested in hospitalized patients.
  
  
  OBJECTIVE
  We aimed to evaluate associations between LAP Index and metabolic profile in a tertiary hospital.
  
  
  METHODS
  Cross-sectional study with 90 inpatients. Lipid profile, fasting glucose, systolic and diastolic blood pressure measurements were obtained from electronic medical records. Weight, height and waist circumferences (WC) were assessed; Body Mass Index (BMI) and LAP Index were calculated. Data were expressed as mean ± standard deviation or percentage. Pearson's correlation and Multiple Linear Regression were used to assess the objectives.
  
  
  RESULTS
  Mean age of participants was 55.03 ± 14.86 years and 47.8% (n = 43) were men. After adjustment for sex, age and physic activity LAP Index (log-transformed) was significantly associated with HDL-cholesterol (p < 0.001), fasting glucose (p = 0.02), systolic blood pressure (p = 0.03) and a trend toward total cholesterol (p = 0.07).
  
  
  CONCLUSIONS
  There are independent association between LAP Index (log-transformed) and metabolic profile in hospitalized patients.
authors.affiliation: Postgraduate Studies Program in Cardiology, Instituto de Cardiologia/Fundação Universitária de Cardiologia do Rio Grande do Sul (IC/FUC), Porto Alegre, RS. Postgraduate Program in Epidemiology, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS.. marcadenti@yahoo.com.br.
authors.forename: Bruna Angelo
authors.initials: BA
authors.lastname: Vieira
authors.affiliation: Postgraduate Studies Program in Cardiology, Instituto de Cardiologia/Fundação Universitária de Cardiologia do Rio Grande do Sul (IC/FUC), Porto Alegre, RS.. marcadenti@yahoo.com.br.
authors.forename: Patrícia
authors.initials: P
authors.lastname: Sauer
authors.affiliation: Department of Nutrition, Universidade Federal de Ciências da Saúde de Porto Alegre (UFSCPA), Porto Alegre, RS.. marcadenti@yahoo.com.br.
authors.forename: Aline
authors.initials: A
authors.lastname: Marcadenti
authors.affiliation: Department of Nutrition, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.. marcadenti@yahoo.com.br.
authors.forename: Carla Haas
authors.initials: CH
authors.lastname: Piovesan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000378:metabolism; D003430:Cross-Sectional Studies; D015444:Exercise; D005260:Female; D006760:Hospitalization; D006801:Humans; D007297:Inpatients; D064237:Lipid Accumulation Product; D050356:Lipid Metabolism; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism
chemical_list: D008055:Lipids