title: [A Case of Corticobasal Syndrome Complicated with Hypopituitarism and Hashimoto's Disease].
abstract: We report the case of an individual with corticobasal syndrome (CBS), hypopituitarism due to a post-traumatic leptomeningeal cyst, and Hashimoto's disease. A 71-year-old woman was admitted to our hospital because of cognitive dysfunction and bradykinesia. Following a primary diagnosis of hypopituitarism and hypothyroidism, she was given hormone replacement therapy, and her clinical symptoms appeared to improve. However, some cognitive impairment and extrapyramidal symptoms remained. The results of careful neurological examinations, as well as magnetic resonance, single-photon emission computed tomography, and positron emission tomography images, suggested a diagnosis of CBS-CBD (corticobasal degeneration). Because parkinsonism and cognitive impairment can be caused by endocrinopathy, it was initially difficult to reach the complete diagnosis that included CBS. Thus, it is important to understand that complicated neurological presentations can be caused by several different disorders.
authors.affiliation: Department of Neurology, Tokyo Metropolitan Geriatric Hospital and Institution of Gerontology.
authors.forename: Satoru
authors.initials: S
authors.lastname: Morimoto
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Kinbara
authors.forename: Makoto
authors.initials: M
authors.lastname: Terada
authors.forename: Tadashi
authors.initials: T
authors.lastname: Komiya
authors.forename: Kenji
authors.initials: K
authors.lastname: Ishii
authors.forename: Masaki
authors.initials: M
authors.lastname: Takao
authors.forename: Kazutomi
authors.initials: K
authors.lastname: Kanemaru
authors.forename: Shigeo
authors.initials: S
authors.lastname: Murayama
mesh_terms: D000368:Aged; D001480:Basal Ganglia Diseases / Q000175:diagnosis*; D002540:Cerebral Cortex / Q000473:pathology; D005260:Female; D050031:Hashimoto Disease / Q000150:complications*; D006801:Humans; D007018:Hypopituitarism / Q000150:complications*; D049268:Positron-Emission Tomography