title: Architecture for an advanced biomedical collaboration domain for the European paediatric cancer research community (ABCD-4-E).
abstract: Today, progress in biomedical research often depends on large, interdisciplinary research projects and tailored information and communication technology (ICT) support. In the context of the European Network for Cancer Research in Children and Adolescents (ENCCA) project the exchange of data between data source (Source Domain) and data consumer (Consumer Domain) systems in a distributed computing environment needs to be facilitated. This work presents the requirements and the corresponding solution architecture of the Advanced Biomedical Collaboration Domain for Europe (ABCD-4-E). The proposed concept utilises public as well as private cloud systems, the Integrating the Healthcare Enterprise (IHE) framework and web-based applications to provide the core capabilities in accordance with privacy and security needs. The utility of crucial parts of the concept was evaluated by prototypic implementation. A discussion of the design indicates that the requirements of ENCCA are fully met. A whole system demonstration is currently being prepared to verify that ABCD-4-E has the potential to evolve into a domain-bridging collaboration platform in the future.
authors.affiliation: AIT Austrian Institute of Technology, Austria.
authors.forename: Michael
authors.initials: M
authors.lastname: Nitzlnader
authors.affiliation: AIT Austrian Institute of Technology, Austria.
authors.forename: Markus
authors.initials: M
authors.lastname: Falgenhauer
authors.affiliation: AIT Austrian Institute of Technology, Austria.
authors.forename: Christian
authors.initials: C
authors.lastname: Gossy
authors.affiliation: AIT Austrian Institute of Technology, Austria.
authors.forename: Günter
authors.initials: G
authors.lastname: Schreier
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration*; D003299:Cooperative Behavior; D057286:Electronic Health Records / Q000458:organization & administration*; D005060:Europe; D006801:Humans; D008495:Medical Oncology / Q000458:organization & administration*; D008498:Medical Record Linkage / Q000379:methods; D009369:Neoplasms / Q000145:classification*; D010348:Patient Care Team / Q000458:organization & administration*; D010372:Pediatrics / Q000458:organization & administration*