title: Chemistry for oncotheranostic gold nanoparticles.
abstract: This review presents in a comprehensive ways the chemical methods used to functionalize gold nanoparticles with focus on anti-cancer applications. The review covers the parameters required for the synthesis gold nanoparticles with defined shapes and sizes, method for targeted delivery in tumours, and selected examples of anti-cancers compounds delivered with gold nanoparticles. A short survey of bioassays for oncology based on gold nanoparticles is also presented.
authors.affiliation: University of Poitiers, UMR CNRS 7285, Institut de Chimie des Milieux et des Matériaux de Poitiers, Equipe Synthèse Organique, 4 rue Michel Brunet, B28, 86073 Poitiers, France.
authors.forename: Anne Juliette
authors.initials: AJ
authors.lastname: Trouiller
authors.affiliation: University of Poitiers, UMR CNRS 7285, Institut de Chimie des Milieux et des Matériaux de Poitiers, Equipe SAMCat, 4 rue Michel Brunet, B27, 86073 Poitiers, France.
authors.forename: Seydou
authors.initials: S
authors.lastname: Hebié
authors.affiliation: University of Poitiers, UMR CNRS 7285, Institut de Chimie des Milieux et des Matériaux de Poitiers, Equipe Synthèse Organique, 4 rue Michel Brunet, B28, 86073 Poitiers, France.
authors.forename: Fatima
authors.initials: F
authors.lastname: El Bahhaj
authors.affiliation: University of Poitiers, UMR CNRS 7285, Institut de Chimie des Milieux et des Matériaux de Poitiers, Equipe SAMCat, 4 rue Michel Brunet, B27, 86073 Poitiers, France.
authors.forename: Teko W
authors.initials: TW
authors.lastname: Napporn
authors.affiliation: University of Poitiers, UMR CNRS 7285, Institut de Chimie des Milieux et des Matériaux de Poitiers, Equipe Synthèse Organique, 4 rue Michel Brunet, B28, 86073 Poitiers, France. Electronic address: Philippe.bertrand@univ-poitiers.fr.
authors.forename: Philippe
authors.initials: P
authors.lastname: Bertrand
mesh_terms: D006046:Gold / Q000737:chemistry* / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D053768:Metal Nanoparticles; D009369:Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*; D000068936:Theranostic Nanomedicine / Q000379:methods*
chemical_list: D006046:Gold
keywords: Cancer; Diagnostic; Gold; Nanoparticles; Therapy