title: Complementary Role of Ultrasound in Management of Gestational Trophoblastic Disease.
abstract: BACKGROUND
  Transvaginal Ultrasonography is a noninvasive and inexpensive medical imaging tool used for the diagnosis of various diseases.
  
  
  OBJECTIVE
  To identify an effective method to identify high-risk patients for developing malignancy after molar evacuation.
  
  
  METHODS
  A prospective serial assessment of 19 patients with gestational trophoblastic disease was performed. Clinical and laboratory data, transvaginal ultrasound and Doppler findings were evaluated the day before evacuation. They were followed-up in the first week after evacuation and every two weeks during the next two months, then every month until the sixth month.
  
  
  RESULTS
  Ovarian theca lutein cysts (P = 0.018) (among pre-evacuation factors) and first week ultrasound (P = 0.02) can help in detecting high-risk patients. Even though, when β-hCG titer is not available in a high-risk patient, post evacuation myometrial involvement (P = 0.005) is a useful sign for detecting persistency.
  
  
  CONCLUSIONS
  Some ultrasonographic features of molar pregnancy have capability to predict malignancy in the course of disease.
authors.affiliation: Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mahrooz
authors.initials: M
authors.lastname: Malek
authors.affiliation: Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Behnaz
authors.initials: B
authors.lastname: Moradi
authors.affiliation: Department of Gynecology Oncology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Azam Sadat
authors.initials: AS
authors.lastname: Mousavi
authors.affiliation: Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Nasrin
authors.initials: N
authors.lastname: Ahmadinejad
authors.affiliation: Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohamad Ali
authors.initials: MA
authors.lastname: Kazemi
authors.affiliation: Department of Radiology, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Masoumeh
authors.initials: M
authors.lastname: Gity
keywords: Doppler; Gestational Trophoblastic Disease; Ultrasound