title: Systematic review of some prosthetic risk factors for periimplantitis.
abstract: BACKGROUND
  The recent literature underlines a correlation between plaque and the development of periimplantitis but neglects the importance of the prosthetic factors.
  
  
  OBJECTIVE
  The purpose of this systematic review was to appraise the available literature to evaluate the role played by cement excess and misfitting components on the development of periimplantitis.
  
  
  METHODS
  An electronic search restricted to the English language was performed in PubMed, Embase, and the Cochrane Register up to September 1, 2014, based on a selected search algorithm. Only cohort studies and case-control studies were included without additional restrictions. The presence of periimplantitis and implant failure were considered primary and secondary outcome variables.
  
  
  RESULTS
  The search produced 275 potentially relevant titles, of which only 2 were found eligible. They showed a correlation in cemented implant prostheses between cement excess and the presence of periimplant disease, especially in patients with a history of periodontal disease. After cement excess removal by means of debridement, disease symptoms disappeared around most of the implants.
  
  
  CONCLUSIONS
  Scientific articles on prosthetic risk factors for periimplantitis are scarce. Although the studies found on cement remnants have a high risk for bias, cement excess seems to be associated with mucositis and possibly with periimplantitis, especially in patients with a history of periodontal disease.
authors.affiliation: Lecturer, Department of surgical and diagnostic sciences, University of Genova, Genova, Italy. Electronic address: paolo.pesce@unige.it.
authors.forename: Paolo
authors.initials: P
authors.lastname: Pesce
authors.affiliation: Lecturer, Dental Institute Toscano, Viareggio, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Canullo
authors.affiliation: Professor, Periodontology Department, Vita-Salute University Milano, Milan, Italy.
authors.forename: Maria Gabriella
authors.initials: MG
authors.lastname: Grusovin
authors.affiliation: Professor, Department of Periodontology and Oral Implantology, Faculty of Medicine and Health Sciences, Dental School, Ghent University, Ghent, Belgium.
authors.forename: Hugo
authors.initials: H
authors.lastname: de Bruyn
authors.affiliation: Professor, Department of Periodontology and Oral Implantology, Faculty of Medicine and Health Sciences, Dental School, Ghent University, Ghent, Belgium; and Professor, Department of Periodontology and Oral Implantology, Vrije Universiteit Brussel (VUB) Belgium, Brussels, Belgium.
authors.forename: Jan
authors.initials: J
authors.lastname: Cosyn
authors.affiliation: Professor, Department of Surgical and Diagnostic Sciences, Division of Prosthodontics, University of Genova, Genova, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Pera
mesh_terms: D016022:Case-Control Studies; D015331:Cohort Studies; D003738:Dental Cements / Q000009:adverse effects; D015921:Dental Implants; D019232:Dental Restoration Failure; D006801:Humans; D057873:Peri-Implantitis / Q000453:epidemiology / Q000209:etiology; D017755:Prosthesis Fitting / Q000592:standards; D012307:Risk Factors
chemical_list: D003738:Dental Cements; D015921:Dental Implants