title: Microincision Hydrophobic Acrylic Aspheric Toric Intraocular Lens for Astigmatism and Cataract Correction.
abstract: OBJECTIVE
  To evaluate the efficacy and safety of a new acrylic one-piece toric intraocular lens (IOL).
  
  
  METHODS
  This prospective multicenter clinical trial included 93 eyes of 61 patients that were implanted with a hydrophobic acrylic toric IOL from 2010 to 2012 and followed for 1 year. This IOL uses the platform of a microincision one-piece aspheric IOL, the NY-60 IOL (HOYA, Tokyo, Japan), with three increments in cylindrical power (NHT15, 1.5 diopters [D]; NHT23, 2.25 D; and NHT30, 3.0 D). The inclusion criterion was preoperative corneal astigmatism from 0.75 to 3.00 D. The primary endpoint was uncorrected distance visual acuity (UDVA) of 0.0 logMAR (20/20 Snellen) or better 6 months postoperatively. In addition to UDVA, corrected distance visual acuity (CDVA), residual astigmatism, stability of the IOL alignment, need of realignment, and the rate of Nd:YAG laser capsulotomy were evaluated up to 1 year postoperatively. Errors in astigmatic correction were assessed using Alpin's vector analysis.
  
  
  RESULTS
  The primary endpoint was achieved in 54.8% of eyes. One year postoperatively, the logMAR UDVAs were 0.02 ± 0.13, 0.05 ± 0.17, and 0.09 ± 0.14 with models NHT15, NHT23, and NHT30, which corresponds to 0.96 (19/20 Snellen), 0.89 (18/20 Snellen), and 0.82 (16/20 Snellen), respectively. One year postoperatively, the residual astigmatism was 0.66 ± 0.58 D. In each evaluation, the mean absolute change in the position of the axis mark was between 1.93° and 2.32°. Three eyes required repositioning of the IOL axis and 2 eyes received Nd:YAG laser capsulotomy. The correction error showed an undercorrection with against-the-rule astigmatism and overcorrection with with-the-rule astigmatism.
  
  
  CONCLUSIONS
  The new one-piece toric IOL provided desirable clinical outcomes and stability in eyes with corneal astigmatism.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Bissen-Miyajima
authors.forename: Kazuno
authors.initials: K
authors.lastname: Negishi
authors.forename: Osamu
authors.initials: O
authors.lastname: Hieda
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kinoshita
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D001251:Astigmatism / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D002386:Cataract / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D003315:Cornea / Q000503:physiopathology*; D005260:Female; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D053844:Lasers, Solid-State; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008866:Microsurgery / Q000379:methods*; D018918:Phacoemulsification / Q000379:methods*; D064727:Posterior Capsulotomy; D011446:Prospective Studies; D011474:Prosthesis Design; D019591:Pseudophakia / Q000503:physiopathology; D012029:Refraction, Ocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000180:Acrylic Resins