title: Antibody and Viral Nucleic Acid Testing of Serum and Cerebrospinal Fluid for Diagnosis of Eastern Equine Encephalitis.
abstract: Eastern equine encephalitis diagnostic serum antibody can appear 6 days after the onset of symptoms, and its numbers can increase 4-fold in 4 days, arguing for early and frequent serum testing. In populations where cerebrospinal fluid viral nucleic acid testing sensitivity and specificity remain undetermined, cerebrospinal antibody testing should also be performed.
authors.affiliation: Department of Health of the State of New York, Syracuse, New York, USA james.sherwood@health.ny.gov.
authors.forename: James A
authors.initials: JA
authors.lastname: Sherwood
authors.affiliation: Department of Health of the State of New York, Syracuse, New York, USA.
authors.forename: David C
authors.initials: DC
authors.lastname: Brittain
authors.affiliation: Department of Health of the State of New York, Syracuse, New York, USA.
authors.forename: John J
authors.initials: JJ
authors.lastname: Howard
authors.affiliation: Department of Health of the State of New York, Syracuse, New York, USA.
authors.forename: JoAnne
authors.initials: J
authors.lastname: Oliver
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood* / Q000134:cerebrospinal fluid*; D002555:Cerebrospinal Fluid / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D020242:Encephalomyelitis, Eastern Equine / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood / Q000134:cerebrospinal fluid; D044967:Serum / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D012367:RNA, Viral