title: [Two cases of Vogt-Koyanagi-Harada disease presenting shallow anterior chamber].
abstract: OBJECTIVE
  We report two cases of Vogt-Koyanagi-Harada disease (VKH) in which shallow anterior chambers were improved after steroid pulse therapy.
  
  
  METHODS
  The patients were women aged 65 and 72. They had headaches, decreased visual acuity and shallow anterior chamber in both eyes. There was no inflammation in the anterior chamber. Ultrasound biomicroscopy (UBM) showed ciliary edema, ciliochoroidal detachment, and angle closure. One case showed high intraocular pressure (IOP), and a diagnosis of acute primary angle closure was made. Although cataract surgery was performed in the left eye, postoperative optical coherence tomography (OCT) revealed serous retinal detachment in both eyes. The shallow anterior chamber and UBM findings were improved and serous retinal detachment disappeared after steroid pulse therapy in both cases.
  
  
  CONCLUSIONS
  VKH may cause shallow anterior chamber and angle closure. The inflammatory changes of VKH in the anterior segment, i. e. ciliary edema and ciliochoroidal detachment, may exacerbate the shallow anterior chambers and narrow angles and result in an acute increase in IOP in eyes with short axial length. VKH associated with shallow anterior chamber may be misdiagnosed as acute primary angle closure. For differential diagnosis, examinations of the ocular fundus including OCT are useful.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Takemoto
authors.forename: Shigeyuki
authors.initials: S
authors.lastname: Ijiri
authors.forename: Michiharu
authors.initials: M
authors.lastname: Shimizu
authors.forename: Tomomi
authors.initials: T
authors.lastname: Higashide
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Sugiyama
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000473:pathology*; D000869:Anterior Eye Segment / Q000473:pathology; D005260:Female; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000473:pathology; D012163:Retinal Detachment / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D016896:Treatment Outcome; D014607:Uveomeningoencephalitic Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D014792:Visual Acuity / Q000502:physiology