title: Consent to Donate Surgical Biospecimens for Research: Perceptions of People With Colorectal Cancer.
abstract: BACKGROUND
  Biospecimens for cancer research are commonly sought from people who undergo surgery for a new diagnosis of cancer, and the demand for these biospecimens is increasing.
  
  
  OBJECTIVE
  The objective of this study was to explore the perceptions of people with colorectal cancer regarding the impact of an opt-in model of consent for biospecimen donation.
  
  
  METHODS
  The qualitative method of Grounded Theory was used, and data were gathered through digitally recorded semistructured interviews with 18 participants. Data were analyzed using the constant comparative method to the descriptive level.
  
  
  RESULTS
  Four major categories were identified describing the response to the consent process used for donating tissue for research purposes. These were as follows: consent is "no big deal" compared with the diagnosis of cancer; helping others; trusting the surgeon; and information related to donation of biospecimens.
  
  
  CONCLUSIONS
  Results from this study indicate that the achievement of ideal informed and voluntary consent is difficult when patients are confronted with the trauma of newly diagnosed illness. Innovative approaches are implicated to obtain consent while protecting the autonomy and dignity of patients.
  
  
  CONCLUSIONS
  The results from this study can contribute to further development of processes for the donation of biospecimens for research purposes that respect the needs and views of patients.
authors.affiliation: Author Affiliations: School of Health Professions, Murdoch University, Perth (Drs Williams and Bulsara); School of Nursing and Midwifery, Edith Cowan University, Joondalup (Drs Williams, Bulsara, and Monterosso and Ms Pienaar); Faculty of Law (Ms Allen), University of Western Australia, Perth (Drs Zeps and Bulsara); School of Nursing and Midwifery (Dr Bulsara), University of Notre Dame, Fremantle (Dr Monterosso); Curtin University, Bentley (Dr Bulsara); and St John of God Healthcare (Drs Zeps and Monterosso); and Sir Charles Gairdner Hospital, Perth (Dr Williams), Western Australia, Australia.
authors.forename: Anne Marjorie
authors.initials: AM
authors.lastname: Williams
authors.forename: Judy
authors.initials: J
authors.lastname: Allen
authors.forename: Nikolajs
authors.initials: N
authors.lastname: Zeps
authors.forename: Catherine
authors.initials: C
authors.lastname: Pienaar
authors.forename: Caroline
authors.initials: C
authors.lastname: Bulsara
authors.forename: Leanne
authors.initials: L
authors.lastname: Monterosso
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001294:Attitude to Health; D035843:Biomedical Research; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D006801:Humans; D007258:Informed Consent / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D036301:Qualitative Research; D014019:Tissue Donors / Q000523:psychology* / Q000706:statistics & numerical data