title: Exploration of extremophiles for high temperature biotechnological processes.
abstract: Industrial processes often take place under harsh conditions that are hostile to microorganisms and their biocatalysts. Microorganisms surviving at temperatures above 60°C represent a chest of biotechnological treasures for high-temperature bioprocesses by producing a large portfolio of biocatalysts (thermozymes). Due to the unique requirements to cultivate thermophilic (60-80°C) and hyperthermophilic (80-110°C) Bacteria and Archaea, less than 5% are cultivable in the laboratory. Therefore, other approaches including sequence-based screenings and metagenomics have been successful in providing novel thermozymes. In particular, polysaccharide-degrading enzymes (amylolytic enzymes, hemicellulases, cellulases, pectinases and chitinases), lipolytic enzymes and proteases from thermophiles have attracted interest due to their potential for versatile applications in pharmaceutical, chemical, food, textile, paper, leather and feed industries as well as in biorefineries.
authors.affiliation: Institute of Technical Microbiology, Hamburg University of Technology (TUHH), Kasernenstr. 12, D-21073 Hamburg, Germany.
authors.forename: Skander
authors.initials: S
authors.lastname: Elleuche
authors.affiliation: Institute of Technical Microbiology, Hamburg University of Technology (TUHH), Kasernenstr. 12, D-21073 Hamburg, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Schäfers
authors.affiliation: Institute of Technical Microbiology, Hamburg University of Technology (TUHH), Kasernenstr. 12, D-21073 Hamburg, Germany.
authors.forename: Saskia
authors.initials: S
authors.lastname: Blank
authors.affiliation: Institute of Technical Microbiology, Hamburg University of Technology (TUHH), Kasernenstr. 12, D-21073 Hamburg, Germany.
authors.forename: Carola
authors.initials: C
authors.lastname: Schröder
authors.affiliation: Institute of Technical Microbiology, Hamburg University of Technology (TUHH), Kasernenstr. 12, D-21073 Hamburg, Germany. Electronic address: antranikian@tuhh.de.
authors.forename: Garabed
authors.initials: G
authors.lastname: Antranikian
mesh_terms: D001105:Archaea / Q000201:enzymology*; D001419:Bacteria / Q000201:enzymology*; D001709:Biotechnology; D044602:Cellulases / Q000378:metabolism; D004798:Enzymes / Q000737:chemistry* / Q000191:economics / Q000302:isolation & purification / Q000378:metabolism; D006358:Hot Temperature; D007218:Industrial Microbiology / Q000379:methods; D056186:Metagenomics; D010447:Peptide Hydrolases / Q000378:metabolism
chemical_list: D004798:Enzymes; D044602:Cellulases; D010447:Peptide Hydrolases