title: Inter-individual stereotypy of the Platynereis larval visual connectome.
abstract: Developmental programs have the fidelity to form neural circuits with the same structure and function among individuals of the same species. It is less well understood, however, to what extent entire neural circuits of different individuals are similar. Previously, we reported the neuronal connectome of the visual eye circuit from the head of a Platynereis dumerilii larva (Randel et al., 2014). We now report a full-body serial section transmission electron microscopy (ssTEM) dataset of another larva of the same age, for which we describe the connectome of the visual eyes and the larval eyespots. Anatomical comparisons and quantitative analyses of the two circuits reveal a high inter-individual stereotypy of the cell complement, neuronal projections, and synaptic connectivity, including the left-right asymmetry in the connectivity of some neurons. Our work shows the extent to which the eye circuitry in Platynereis larvae is hard-wired.
authors.affiliation: Max Planck Institute for Developmental Biology, Tübingen, Germany.
authors.forename: Nadine
authors.initials: N
authors.lastname: Randel
authors.affiliation: Max Planck Institute for Developmental Biology, Tübingen, Germany.
authors.forename: Réza
authors.initials: R
authors.lastname: Shahidi
authors.affiliation: Max Planck Institute for Developmental Biology, Tübingen, Germany.
authors.forename: Csaba
authors.initials: C
authors.lastname: Verasztó
authors.affiliation: Max Planck Institute for Developmental Biology, Tübingen, Germany.
authors.forename: Luis A
authors.initials: LA
authors.lastname: Bezares-Calderón
authors.affiliation: Max Planck Institute for Developmental Biology, Tübingen, Germany.
authors.forename: Steffen
authors.initials: S
authors.lastname: Schmidt
authors.affiliation: Max Planck Institute for Developmental Biology, Tübingen, Germany.
authors.forename: Gáspár
authors.identifier: http://orcid.org/0000-0001-8496-9836
authors.initials: G
authors.lastname: Jékely
mesh_terms: D000818:Animals; D063132:Connectome; D007814:Larva / Q000033:anatomy & histology / Q000502:physiology; D046529:Microscopy, Electron, Transmission; D008867:Microtomy; D011077:Polychaeta / Q000033:anatomy & histology* / Q000502:physiology*; D014785:Vision, Ocular; D014796:Visual Perception
keywords: Platynereis dumerilii; connectome; neural circuit; neuroscience; stereotypy