title: Calreticulin Mutated Essential Thrombocythemia Presenting as Acute Coronary Syndrome.
abstract: Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterized by a clonal expansion of megakaryocytes. ET can result in both arterial and venous thrombosis. Involvement of the coronary arteries has been reported. Patients who harbor a CALR mutation are half as likely to suffer a thrombotic event as compared to patients with a JAK2 mutation. We report a case of CALR-mutated ET whose initial disease manifestation was a non-ST segment elevation myocardial infarction.
authors.affiliation: Department of Medicine, Staten Island University Hospital, Staten Island, NY 10305, USA.
authors.forename: Bassel
authors.initials: B
authors.lastname: Nazha
authors.affiliation: Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY 10305, USA.
authors.forename: Gwenalyn
authors.initials: G
authors.lastname: Garcia
authors.affiliation: Department of Cardiology, Staten Island University Hospital, Staten Island, NY 10305, USA.
authors.forename: Ruben
authors.initials: R
authors.lastname: Kandov
authors.affiliation: Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY 10305, USA.
authors.forename: Marcel
authors.initials: M
authors.lastname: Odaimi