title: Chest Wall Reconstruction Using Sternal Plating in Patients With Complex Sternal Dehiscence.
abstract: To evaluate the effectiveness of sternal reconstruction using demineralized bone matrix in patients with complex sternal dehiscence. In this retrospective review, 14 patients with complex sternal wounds with dehiscence were evaluated after specific reconstructive methods. The steps involved ensuring sternal salvage by eradicating infection with a combination of vacuum assisted closure and antibiotic therapy. In a separate setting, patients underwent sternal reconstruction with plate fixation and local use of bone morphogenetic protein (BMP; Infuse, Medtronic, Minneapolis, MN) and demineralized bone matrix for remaining sternal defects. Pectoral myocutaneous flaps were then used to cover the sternum. Patients were evaluated daily in the immediate postoperative period for sternal wound complications and pain and were followed up at 3 and 6 months postoperatively. At 6 month after the procedure, all patients had stable chest walls with no further sternal instability and no recurrent dehiscences or wound infections. All patients returned to normal activity with complete resolution of sternal pain. Complex sternal wounds can be reconstructed and repaired effectively with a combination of bone salvage, local therapy with BMP, and flap closure, with encouraging results.
authors.affiliation: Department of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Illinois. Electronic address: bharat.pancholy@va.gov.
authors.forename: Bharat
authors.initials: B
authors.lastname: Pancholy
authors.affiliation: Department of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, Illinois.
authors.forename: Jai
authors.initials: J
authors.lastname: Raman
mesh_terms: D001860:Bone Plates; D005500:Follow-Up Studies; D006801:Humans; D012189:Retrospective Studies; D013249:Sternum / Q000601:surgery*; D013529:Surgical Wound Dehiscence / Q000601:surgery*; D035441:Thoracic Wall / Q000601:surgery*; D013905:Thoracoplasty / Q000379:methods*; D014945:Wound Healing