title: Current status of transcatheter aortic valve replacement.
abstract: The advent of transcatheter aortic valve replacement (TAVR) has modified the treatment of severe aortic stenosis (AS). Large randomized trials and multicenter registries have endorsed the efficacy of TAVR in improving outcomes in patients with severe AS who are inoperable or high surgical risk. There has been a noticeable shift in using TAVR in patients with AS who are not at a high surgical risk. Appropriate diagnosis, patient selection, and referral remain cornerstones to achieving optimal outcomes after TAVR or SAVR (surgical aortic valve replacement).
authors.affiliation: Department of Cardiology, Policlinico Tor Vergata, University of Rome, Tor Vergata, Viale Oxford 81, Rome 00133, Italy. Electronic address: ksarkarmd@gmail.com.
authors.forename: Kunal
authors.initials: K
authors.lastname: Sarkar
authors.affiliation: Division of General Internal Medicine, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
authors.forename: Mrinalini
authors.initials: M
authors.lastname: Sarkar
authors.affiliation: Department of Cardiology, Policlinico Tor Vergata, University of Rome, Tor Vergata, Viale Oxford 81, Rome 00133, Italy.
authors.forename: Gian Paolo
authors.initials: GP
authors.lastname: Ussia
mesh_terms: D000367:Age Factors; D001024:Aortic Valve Stenosis / Q000601:surgery*; D002986:Clinical Trials as Topic; D015897:Comorbidity; D006350:Heart Valve Prosthesis; D006801:Humans; D018579:Patient Selection; D018570:Risk Assessment; D012307:Risk Factors; D012720:Severity of Illness Index; D020521:Stroke / Q000209:etiology; D065467:Transcatheter Aortic Valve Replacement / Q000009:adverse effects / Q000379:methods*
keywords: Aortic stenosis; Surgical aortic valve replacement; Transcatheter aortic valve replacement; Valvular heart disease