title: [Endogenous Candida lens abscess in a premature infant].
abstract: BACKGROUND
  This case report describes an extremely rare Candida lens abscess in a premature infant (gestational age 24 weeks at birth).
  
  
  METHODS
  After birth the infant suffered from Candida sepsis which was successfully treated with an antifungal medication. The patient was referred at the age of 6 months because of greyish alterations in the pupils but an absence of other symptoms. The examination with the patient under general anesthesia revealed a grey pupillary membrane and behind it a whitish swollen lens. A lensectomy was performed. The vitreous body was inconspicuous. Candida albicans was identified microbiologically.
  
  
  CONCLUSIONS
  In preterm infants dissemination of pathogens into the lens through the vascular coat of the lens is possible, which after regression of the coat is no longer accessible to systemic treatment and may thus be manifested as delayed abscess formation.
authors.affiliation: Augenklinik des Klinikums Wiesbaden, Dr. Horst-Schmidt-Kliniken, Ludwig-Erhard-Straße 100, 65199, Wiesbaden, Deutschland. Achim.Fiess@hsk-wiesbaden.de.
authors.forename: Achim
authors.initials: A
authors.lastname: Fieß
authors.affiliation: Klinik für Kinder und Jugendliche, Dr. Horst-Schmidt-Kliniken, Wiesbaden, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Bauer
authors.affiliation: Institut für Labordiagnostik und Hygiene, Dr. Horst-Schmidt-Kliniken, Wiesbaden, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Schindel
authors.affiliation: Klinik für Kinder und Jugendliche, Dr. Horst-Schmidt-Kliniken, Wiesbaden, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Knuf
authors.affiliation: Augenklinik des Klinikums Wiesbaden, Dr. Horst-Schmidt-Kliniken, Ludwig-Erhard-Straße 100, 65199, Wiesbaden, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Dithmar
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000628:therapy; D002177:Candidiasis / Q000175:diagnosis* / Q000628:therapy; D003937:Diagnosis, Differential; D015821:Eye Infections, Fungal / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis* / Q000628:therapy; D007905:Lens Diseases / Q000175:diagnosis* / Q000628:therapy; D016896:Treatment Outcome
keywords: Candida endophthalmitis; Lensectomy; Premature birth; Sepsis; Therapy