title: 2014 Guideline for the Management of High Blood Pressure (Eighth Joint National Committee): Take-Home Messages.
abstract: The JNC 8 guidelines focus on 3 highest-ranked clinical questions that include BP thresholds for starting therapy, specific BP goals, and risks and benefits of specific antihypertensive drugs. Only randomized controlled trial data were used and JNC 8 panel did not include observational studies, systematic reviews, or meta-analyses. The investigators also suggested that benefit of lowering BP to less than 140/90 is not clear. Lifestyle modifications were considered very important for all patients with hypertension. These recommendations are not alternatives for clinical judgment, and decisions about medical care must be individualized to each patient.
authors.affiliation: Division of Nephrology, Penn State College of Medicine, Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA. Electronic address: ufarooq@hmc.psu.edu.
authors.forename: Umar
authors.initials: U
authors.lastname: Farooq
authors.affiliation: Division of Nephrology, Penn State College of Medicine, Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA.
authors.forename: Sunita G
authors.initials: SG
authors.lastname: Ray
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D001741:Black or African American; D000367:Age Factors; D057911:Angiotensin Receptor Antagonists / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001794:Blood Pressure; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D048909:Diabetes Complications; D019468:Disease Management; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D017410:Practice Guidelines as Topic; D051436:Renal Insufficiency, Chronic / Q000150:complications; D049993:Sodium Chloride Symporter Inhibitors / Q000627:therapeutic use
chemical_list: D000319:Adrenergic beta-Antagonists; D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D049993:Sodium Chloride Symporter Inhibitors
keywords: Blood pressure goals; Blood pressure treatment; High blood pressure; JNC8