title: The effect of synthesis parameters on the geometry and dimensions of mesoporous hydroxyapatite nanoparticles in the presence of 1-dodecanethiol as a pore expander.
abstract: Mesoporous hydroxyapatite with different pore diameters and pore volumes were synthesized by the self-assembly method using Cetyltrimethylammonium bromide (CTAB) as the cationic surfactant and 1-dodecanethiol as the pore expander at different micellization pHs, solvent types and surfactant concentrations. Results of field emission scanning electron microscopy (FESEM) showed a decrease in length/diameter ratio of rod-like particles by an increase in micellization pH and also a sphere to rod transition in morphology by an increase in CTAB concentration. Brunauer-Emmett-Teller (BET) surface area and Low angle X-ray diffraction analysis revealed that the optimized mesoporous hydroxyapatite with controlled pore structure can be obtained under basic micellization pH (about 12, pH of complete ionization of 1-dodecanethiol) by using water as the solvent and a high content of cationic surfactant. The results also show that micellization pH has a strong effect on pore structure and changing the pH can shift the mesostructure to a macroporous structure with morphological changes.
authors.affiliation: School of Metallurgical and Materials Engineering, Iran University of Science and Technology, Tehran, Narmak 16844, Iran.
authors.forename: L
authors.initials: L
authors.lastname: Bakhtiari
authors.affiliation: School of Metallurgical and Materials Engineering, Iran University of Science and Technology, Tehran, Narmak 16844, Iran. Electronic address: hrezaie@iust.ac.ir.
authors.forename: H R
authors.initials: HR
authors.lastname: Rezaie
authors.affiliation: School of Metallurgical and Materials Engineering, Iran University of Science and Technology, Tehran, Narmak 16844, Iran.
authors.forename: J
authors.initials: J
authors.lastname: Javadpour
authors.affiliation: Shahid Beheshti University of Medical Sciences, Tehran 6153-14155, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Erfan
authors.affiliation: National Cell Bank of Iran, Pasteur Institute of Iran, Tehran 13164, Iran.
authors.forename: M A
authors.initials: MA
authors.lastname: Shokrgozar
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D000077286:Cetrimonium; D002593:Cetrimonium Compounds; D017886:Durapatite / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008823:Micelles; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D016062:Porosity; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D002593:Cetrimonium Compounds; D008823:Micelles; D013438:Sulfhydryl Compounds; C013976:dodecylmercaptan; D017886:Durapatite; D000077286:Cetrimonium
keywords: 1-Dodecanethiol; CTAB; Hydroxyapatite; Mesoporous; Micellization