title: Prospective evaluation of the renal morphology and vascular resistance in patients with ankylosing spondylitis.
abstract: OBJECTIVE
  To evaluate renal morphology, prevalence of urinary stone disease, renal perfusion and resistance to renal blood flow in patients with ankylosing spondylitis(AS).
  
  
  METHODS
  Thirty-eight patients diagnosed with AS and with normal basal renal functions, together with 38 healthy individuals matched in terms of age, sex, blood lipid profile and body mass index, were included. Total cholesterol, triglyceride, urea, creatinine and glucose levels were measured in both groups, as well as vitamin D, erythrocyte sedimentation rate (ESR) and C-reactive protein in the AS group. Renal dimensions, parenchymal echogenicity, presence of stone and renal resistive index (RRI) from the interlobular artery level were measured, and correlations with clinical and laboratory parameters were assessed.
  
  
  RESULTS
  Thirty-eight patients diagnosed with AS (age 42.4+/- 11.5, 24 male, 14 women) and a control group of 38 healthy individuals (age 41.7+/-10.8, 23 male, 15 female) were included in the study. Renal stone was present in 7 patients (18.4%) in the AS group and 4 subjects (10.5%) in the control group. There was no significant difference in prevalence of stone between the groups (p=0.516). RRI values were significantly higher in the patients with AS (0.63+/-0.06) compared with the control group (0.59+/-0.03, p=0.001). Significant correlations were determined between RRI and age, triglyceride level, body mass index and length of disease.
  
  
  CONCLUSIONS
  Renal Doppler is an important examination in early diagnosis and monitoring of renal changes in AS patients since renal complications in AS develop in the chronic and follow a subclinical course.
authors.affiliation: Department of Radiology, Canakkale Onsekiz Mart University, Faculty of Medicine, Canakkale, Turkey. mustafaresorlu77@gmail.com.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Resorlu
authors.affiliation: Department of Physical Medicine and Rehabilitation,Canakkale Onsekiz Mart University, Faculty of Medicine, Canakkale, Turkey.
authors.forename: Ferhat
authors.initials: F
authors.lastname: Gokmen
authors.affiliation: Department of Surgery, Bezmialem Vakif University, Faculty of Medicine, Istanbul, Turkey.
authors.forename: Hatice
authors.initials: H
authors.lastname: Resorlu
authors.affiliation: Department of Radiology, Canakkale Onsekiz Mart University, Faculty of Medicine, Canakkale, Turkey.
authors.forename: Gurhan
authors.initials: G
authors.lastname: Adam
authors.affiliation: Department of Radiology, Canakkale Onsekiz Mart University, Faculty of Medicine, Canakkale, Turkey.
authors.forename: Nilufer
authors.initials: N
authors.lastname: Aylanc
authors.affiliation: Department of Physical Medicine and Rehabilitation,Canakkale Onsekiz Mart University, Faculty of Medicine, Canakkale, Turkey.
authors.forename: Ayla
authors.initials: A
authors.lastname: Akbal
authors.affiliation: Department of Radiology, Canakkale Onsekiz Mart University, Faculty of Medicine, Canakkale, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Ozdemir
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose; D001799:Blood Sedimentation; D002097:C-Reactive Protein; D002784:Cholesterol / Q000097:blood; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D007669:Kidney Calculi / Q000097:blood / Q000000981:diagnostic imaging; D008297:Male; D011446:Prospective Studies; D013167:Spondylitis, Ankylosing / Q000097:blood / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D014280:Triglycerides / Q000097:blood; D014463:Ultrasonography; D014508:Urea / Q000097:blood; D014655:Vascular Resistance / Q000502:physiology*
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D014280:Triglycerides; D014508:Urea; D002097:C-Reactive Protein; D002784:Cholesterol; D003404:Creatinine