title: The importance of the mean platelet volume in the diagnosis of supraventricular tachycardia.
abstract: BACKGROUND
  The diagnosis of palpitation can be difficult in the emergency department (ED) and the waiting time for a first appointment with an arrhythmia clinic can be very long. The inflammation is sufficient to facilitate the initiation of supraventricular tachyarrhythmia (SVT). The increased mean platelet volume (MPV) is closely correlated with inflammation and to reflect inflammatory burden in different condition.
  
  
  OBJECTIVE
  In this study, we aimed to investigate the relation between MPV and SVT in patient with documented atrial tachyarrhythmia in ED.
  
  
  METHODS
  Two study groups were compared; a SVT group with arrive at the ED with documented SVT (n=122) and 100 healthy adult without any palpitation symptom, arrhythmic disease, and with normal physical examination results that were brought for checkups to the cardiology polyclinic were classified as control group. Blood samples were obtained from all patients for determining the hematologic counts and MPV during first hour in ED period.
  
  
  RESULTS
  In terms of the focus of the study, hemoglobin, neutrophil count, mean cell volume (MCV), red cell distribution width (RDW), platelet, white blood cell (WBC), and lymphocyte counts were similar in both group (p>0.05). MPV in the SVT group was signifi cantly higher than in the control group (9.12±1.22 fl vs 8.64±0.89 fl , p<0.001). Multivariate logistic regression analysis showed that just MPV was independent predictor of SVT in patients with palpitation in ED (odds ratio [OR] 8.497, 95% confidence interval (6.181 to 12.325), p=0.012).
  
  
  CONCLUSIONS
  Our study described that MPV is helpful parameter for the diagnosis of SVT in emergency department, for the first time in the literature.
authors.affiliation: Department of Emergency Medicine, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.
authors.forename: Tarik
authors.initials: T
authors.lastname: Ocak
authors.affiliation: Department of Cardiology, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.
authors.forename: Alim
authors.initials: A
authors.lastname: Erdem
authors.affiliation: Department of Emergency Medicine, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.
authors.forename: Arif
authors.initials: A
authors.lastname: Duran
authors.affiliation: Department of Anesthesiology and Reanimation, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.
authors.forename: Ümit Yaşar
authors.initials: ÜY
authors.lastname: Tekelioğlu
authors.affiliation: Department of Cardiology, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Öztürk
authors.affiliation: Department of Cardiology, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.
authors.forename: Suzi Selim
authors.initials: SS
authors.lastname: Ayhan
authors.affiliation: Department of Cardiology, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.
authors.forename: Mehmet Fatih
authors.initials: MF
authors.lastname: Özlü
authors.affiliation: Department of Cardiology, Abant Izzet Baysal University School of Medicine, Bolu, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yazici
mesh_terms: D001145:Arrhythmias, Cardiac / Q000378:metabolism*; D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D006325:Heart Atria / Q000378:metabolism*; D006801:Humans; D008297:Male
chemical_list: D002097:C-Reactive Protein
keywords: diagnostic; inflammation; mean platelet volume; palpitation; supraventricular tachycardia