title: Turn Up the Volume: Uncovering Nucleus Size Control Mechanisms.
abstract: Reporting in Developmental Cell, Hara and Merten (2015) apply the use of microfabrication and in vitro analysis in cell-free extracts to the old problem of nuclear size control. The authors make insights into the regulation of nuclear growth that potentially explain the widely reported correlation between nucleus size and cell size.
authors.affiliation: Department of Cell and Developmental Biology and Department of Bioengineering, University of Pennsylvania, 421 Curie Blvd, Philadelphia, PA 19104, USA. Electronic address: mattgood@mail.med.upenn.edu.
authors.forename: Matthew C
authors.initials: MC
authors.lastname: Good
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000502:physiology*; D004398:Dyneins / Q000378:metabolism*; D005260:Female; D008870:Microtubules / Q000378:metabolism*; D009685:Nuclear Envelope / Q000502:physiology*; D009865:Oocytes / Q000166:cytology* / Q000378:metabolism*; D014982:Xenopus laevis / Q000378:metabolism*
chemical_list: D004398:Dyneins