title: Towards sustainable data management in professional biobanking.
abstract: BACKGROUND
  Professional biobanks become increasingly important for fostering personalized medicine. While setting up and operating a high-quality collection of biomaterial specimens, biobank managers must face several challenges concerning quality management.
  
  
  OBJECTIVE
  Designing and implementing a data management, which ensures patient's privacy and simultaneously provides researchers with all relevant patient information, is particularly demanding. The requirements of all involved stakeholders must be considered without impairing the biobank's efficiency.
  
  
  METHODS
  To link biomaterial samples to medical data documented in different contexts, an asymmetric encryption scheme with pseudonymization for existing clinical identifiers was implemented.
  
  
  RESULTS
  The presented pseudonymization scheme allows establishing a comprehensive flow for pseudonymized data for biomaterial samples.
  
  
  CONCLUSIONS
  Most of the content stored in clinical databases, except for personally identifying data, can be evaluated, combined with individually documented medical data and associated this to a biomaterial sample without revealing personally identifying data.
authors.affiliation: RWTH cBMB, Institute of Pathology, University Hospital RWTH Aachen.
authors.forename: Philipp
authors.initials: P
authors.lastname: Leusmann
authors.affiliation: RWTH cBMB, Institute of Pathology, University Hospital RWTH Aachen.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Veeck
authors.affiliation: RWTH cBMB, Institute of Pathology, University Hospital RWTH Aachen.
authors.forename: Jörg
authors.initials: J
authors.lastname: Jäkel
authors.affiliation: RWTH cBMB, Institute of Pathology, University Hospital RWTH Aachen.
authors.forename: Edgar
authors.initials: E
authors.lastname: Dahl
authors.affiliation: RWTH cBMB, Institute of Pathology, University Hospital RWTH Aachen.
authors.forename: Ruth
authors.initials: R
authors.lastname: Knüchel-Clarke
authors.affiliation: Department of Medical Informatics, University Hospital RWTH Aachen.
authors.forename: Cord
authors.initials: C
authors.lastname: Spreckelsen
mesh_terms: D018070:Biological Specimen Banks / Q000592:standards*; D016494:Computer Security / Q000592:standards*; D003219:Confidentiality / Q000592:standards*; D000068598:Data Accuracy; D057286:Electronic Health Records / Q000592:standards*; D005858:Germany; D016247:Information Storage and Retrieval / Q000592:standards; D062527:Meaningful Use / Q000592:standards*; D008498:Medical Record Linkage / Q000592:standards; D017410:Practice Guidelines as Topic