title: Imaging guided mediastinal percutaneal core biopsy--technique and complications.
abstract: 165 percutaneous biopsies of anterior, middle and posterior mediastinum lesions were performed to 156 patients. Procedure was guided by US in 40 cases, by CT - in 125 cases. Hydrodissection was used in 5 cases, artificial pneumothorax - in 3 cases in order to avoid transpulmonary needle pass. Post-biopsy CT scan was performed and patients observed for any complications. Adequate tissue for histological diagnosis was obtained in 156 (94.5%) cases at the first attempt; in 9 (5.5%) cases the repeated procedure was needed. No major complications were detected after biopsy procedures; minor complications (pneumothorax, hemothorax and hemophtysis) were detected in 23 (13.9%) cases. No complications were detected after US guided procedures; In 17 (10.3% of all complications) cases pneumothorax, in 4 (2.4%) cases - hemothorax and in 2 (1.2%) cases hemophtisis was detected on CT guided procedures. All hemothorax and hemophtisis and 10 pneumothorax cases happened to be self-limited; in 3 pneumothorax cases aspiration and in 4 cases - pleural drainage was needed. Percutaneous image-guided core biopsy of mediastinal lesions is an accurate and safe procedure, which enables to get the tissue material from all mediastinum compartments. Ultrasound is the most efficient for biopsy guidance, if the target is adequately imaged by it; the advantages of US guidance are: a) possibility of real-time needle movement control b) possibility of real-time blood flow imaging b) noninvasiveness c) cost-effectiveness d) possibility to perform the biopsy at the bedside, in a semiupright position; so, ultrasound is a "Gold Standard" for procedure guidance if the 'target" can be adequately imaged by this technique. If US guidance is impossible biopsy should be performed under CT guidance. Hydrodissection and artificial pneumothorax enables to avoid the lung tissue penetration related complications. Pneumothorax was associated with multiple Needle passes and larger diameter needle use. The safety and biopsy procedure success high rate proves the use of IGMPCB as a first choice procedure when the mediastinal mass morphology is needed.
authors.affiliation: Tbilisi State Medical University, High Technology Medical Center - University Clinic; Clinic Cortex, Tbilisi, Georgia.
authors.forename: T
authors.initials: T
authors.lastname: Azrumelashvili
authors.affiliation: Tbilisi State Medical University, High Technology Medical Center - University Clinic; Clinic Cortex, Tbilisi, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Mizandari
authors.affiliation: Tbilisi State Medical University, High Technology Medical Center - University Clinic; Clinic Cortex, Tbilisi, Georgia.
authors.forename: D
authors.initials: D
authors.lastname: Magalashvili
authors.affiliation: Tbilisi State Medical University, High Technology Medical Center - University Clinic; Clinic Cortex, Tbilisi, Georgia.
authors.forename: T
authors.initials: T
authors.lastname: Dundua
mesh_terms: D006801:Humans; D061705:Image-Guided Biopsy / Q000009:adverse effects / Q000379:methods*; D008168:Lung / Q000000981:diagnostic imaging / Q000503:physiopathology; D008482:Mediastinum / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011030:Pneumothorax / Q000000981:diagnostic imaging* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed