title: [Mayer-Rokitansky-Küster-Hauser syndrome: two cases report].
abstract: Agenesia of the Müllerian ducts is a low-frequency congenital disease but with devastating effects on women's reproductive health. In this paper we present two cases of women affected by Mayer-Rokitansky-Küster-Hauser syndrome (MRKH). First case was a 17-year-old woman with aplasia of the upper vagina and absence of uterus. No other defects were found and was classified as type 1-MRKH. Second case was 18-year-old woman with absence of uterus, escoliosis and polycystic ovary syndrome, classified as type II-MRKH. Patients were seen at the Hospital with primary amenorrhea and fully developed secondary sexual characteristics. A clinical follow-up protocol, including the use of high-resolution image studies was used for diagnosis. Diagnostic procedures and current medical approaches to the treatment of MRKH are discussed, including psychological advisory, surgical procedures and new tissue-engineering techniques.
authors.forename: Marco Antonio
authors.initials: MA
authors.lastname: Ávila-Vergara
authors.forename: Damián Alfredo
authors.initials: DA
authors.lastname: León-Álvarez
authors.forename: Miriam Nayeli
authors.initials: MN
authors.lastname: López-Villegas
authors.forename: Samantha Melissa
authors.initials: SM
authors.lastname: Quintero-Medrano
authors.forename: Gladys Fabiola
authors.initials: GF
authors.lastname: Angulo-Bueno
authors.forename: Felipe
authors.initials: F
authors.lastname: Vadillo-Ortega
mesh_terms: D058489:46, XX Disorders of Sex Development / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D000293:Adolescent; D000568:Amenorrhea / Q000209:etiology*; D000013:Congenital Abnormalities / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D009095:Mullerian Ducts / Q000002:abnormalities* / Q000503:physiopathology; D023822:Tissue Engineering / Q000379:methods