title: Peyronie's Disease: AUA Guideline.
abstract: OBJECTIVE
  The purpose of this guideline is to provide a clinical framework for the diagnosis and treatment of Peyronie's disease.
  
  
  METHODS
  A systematic review of the literature using the PubMed®, EMBASE® and Cochrane databases (search dates 1/1/1965 to 1/26/15) was conducted to identify peer-reviewed publications relevant to the diagnosis and treatment of PD. The review yielded an evidence base of 303 articles after application of inclusion/exclusion criteria.
  
  
  RESULTS
  The systematic review was used to create guideline statements regarding treatment of PD. When sufficient evidence existed, the body of evidence for a particular treatment was assigned a strength rating of A (high quality evidence; high certainty), B (moderate quality evidence; moderate certainty), or C (low quality evidence; low certainty). Evidence-based statements of Strong, Moderate, or Conditional Recommendation were developed based on benefits and risks/burdens to patients. Additional consensus statements related to the diagnosis of PD are provided as Clinical Principles and Expert Opinions due to insufficient published evidence.
  
  
  CONCLUSIONS
  There is a continually expanding literature on PD; the Panel notes that this document constitutes a clinical strategy and is not intended to be interpreted rigidly. The most effective approach for a particular patient is best determined by the individual clinician and patient in the context of that patient's history, values, and goals for treatment. As the science relevant to PD evolves and improves, the strategies presented here will be amended to remain consistent with the highest standards of clinical care.
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Ajay
authors.initials: A
authors.lastname: Nehra
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Ralph
authors.initials: R
authors.lastname: Alterowitz
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Culkin
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Martha M
authors.initials: MM
authors.lastname: Faraday
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Lawrence S
authors.initials: LS
authors.lastname: Hakim
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Joel J
authors.initials: JJ
authors.lastname: Heidelbaugh
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Mohit
authors.initials: M
authors.lastname: Khera
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Erin
authors.initials: E
authors.lastname: Kirkby
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Kevin T
authors.initials: KT
authors.lastname: McVary
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Martin M
authors.initials: MM
authors.lastname: Miner
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Christian J
authors.initials: CJ
authors.lastname: Nelson
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Hossein
authors.initials: H
authors.lastname: Sadeghi-Nejad
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Allen D
authors.initials: AD
authors.lastname: Seftel
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Alan W
authors.initials: AW
authors.lastname: Shindel
authors.affiliation: American Urological Association Education and Research, Inc., Linthicum, Maryland.
authors.forename: Arthur L
authors.initials: AL
authors.lastname: Burnett
mesh_terms: D000465:Algorithms; D006801:Humans; D008297:Male; D010411:Penile Induration / Q000175:diagnosis* / Q000628:therapy*
keywords: fibrosis; penile induration; penis