title: Human African trypanosomiasis prevention, treatment and control costs: a systematic review.
abstract: The control and eventual elimination of human African trypanosomiasis (HAT) requires the expansion of current control and surveillance activities. A systematic review of the published literature on the costs of HAT prevention, treatment, and control, in addition to the economic burden, was conducted. All studies that contained primary or secondary data on costs of prevention, treatment and control were considered, resulting in the inclusion of 42 papers. The geographically focal nature of the disease and a lack of standardization in the cost data limit the usefulness of the available information for making generalizations across diverse settings. More recent information on the costs of treatment and control interventions for HAT is needed to provide accurate information for analyses and planning. The cost information contained herein can be used to inform rational decision making in control and elimination programs, and to assess potential synergies with existing vector-borne disease control programs, but programs would benefit significantly from new cost data collection.
authors.affiliation: Center for Applied Malaria Research and Evaluation, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, Suite 2200, New Orleans, LA 70112, USA; Department of Tropical Medicine, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, Suite 2309, New Orleans, LA 70112, USA. Electronic address: jkeating@tulane.edu.
authors.forename: Joseph
authors.initials: J
authors.lastname: Keating
authors.affiliation: Center for Applied Malaria Research and Evaluation, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, Suite 2200, New Orleans, LA 70112, USA; Department of Tropical Medicine, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, Suite 2309, New Orleans, LA 70112, USA. Electronic address: jyukich@tulane.edu.
authors.forename: Joshua O
authors.initials: JO
authors.lastname: Yukich
authors.affiliation: Department of Epidemiologyand Public Health, Swiss Tropicaland Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland; University of Basel, Switzerland. Electronic address: simone.sutherland@unibas.ch.
authors.forename: C Simone
authors.initials: CS
authors.lastname: Sutherland
authors.affiliation: Sightsavers, 35 Perrymount Road, Haywards Heath, West Sussex, RH16 3BW, UK. Electronic address: gwoods@sightsavers.org.
authors.forename: Geordie
authors.initials: G
authors.lastname: Woods
authors.affiliation: Department of Epidemiologyand Public Health, Swiss Tropicaland Public Health Institute, Socinstrasse 57, 4002 Basel, Switzerland; University of Basel, Switzerland; Centre for Research on Health and Social Care Management (CERGAS), UniversitàBocconi, Milan, Italy. Electronic address: fabrizio.tediosi@unibas.ch.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Tediosi
mesh_terms: D000818:Animals; D002417:Cattle; D017048:Health Care Costs; D006760:Hospitalization / Q000191:economics; D006801:Humans; D007300:Insect Control / Q000191:economics*; D014353:Trypanosomiasis, African / Q000188:drug therapy / Q000517:prevention & control*; D014370:Tsetse Flies
keywords: Control; Cost; Prevention; Sleeping sickness; Treatment; Trypanosomiasis