title: Analytical strategy based on the combination of gas chromatography coupled to time-of-flight and hybrid quadrupole time-of-flight mass analyzers for non-target analysis in food packaging.
abstract: The potential of an advanced analytical strategy based on the use of gas chromatography (GC) coupled to high resolution mass spectrometry (HRMS) with two different analyzers and ionization sources has been investigated and applied to the non-target analysis of food packaging contaminants. Initially, the approach based on GC-time-of-flight (TOF) MS with electron ionization (EI) source allowed performing a library search and mass accurate measurements of selected ions. Then, a second analysis was performed using hybrid quadrupole (Q) TOF MS with an atmospheric pressure chemical ionization (APCI) source in order to search for the molecular ion or the protonated molecule and study the fragmentation behavior. This analytical strategy was applied to the analysis of four polypropylene/ethylene vinyl alcohol/polypropylene (PP/EVOH/PP) multilayer trays and one PP/Al foil/PP film, each one subjected to migration assays with the food simulants isooctane and Tenax®, in order to investigate its potential on the determination of migrant substances.
authors.affiliation: Research Institute for Pesticides and Water, University Jaume I, 12071 Castellón, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Cherta
authors.affiliation: Research Institute for Pesticides and Water, University Jaume I, 12071 Castellón, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Portolés
authors.affiliation: Research Institute for Pesticides and Water, University Jaume I, 12071 Castellón, Spain. Electronic address: epitarch@uji.es.
authors.forename: E
authors.initials: E
authors.lastname: Pitarch
authors.affiliation: Research Institute for Pesticides and Water, University Jaume I, 12071 Castellón, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Beltran
authors.affiliation: Research Institute for Pesticides and Water, University Jaume I, 12071 Castellón, Spain.
authors.forename: F J
authors.initials: FJ
authors.lastname: López
authors.affiliation: AINIA-Centro Tecnológico, Benjamín Franklin 5-11, 46980 Paterna, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Calatayud
authors.affiliation: AINIA-Centro Tecnológico, Benjamín Franklin 5-11, 46980 Paterna, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Company
authors.affiliation: Research Institute for Pesticides and Water, University Jaume I, 12071 Castellón, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Hernández
mesh_terms: D005504:Food Analysis; D005506:Food Contamination / Q000032:analysis; D018857:Food Packaging; D008401:Gas Chromatography-Mass Spectrometry; D007477:Ions / Q000737:chemistry; D013058:Mass Spectrometry
chemical_list: D007477:Ions
keywords: Atmospheric pressure chemical ionization; Electron ionization; Food packaging; Gas chromatography; High resolution mass spectrometry; PP/Al foil/PP; PP/EVOH/PP; Potential migrants