title: Heart failure: not a single organ disease but a multisystem syndrome.
abstract: Heart failure is not simply a single organ disease; rather it is a complex multi-system clinical syndrome, with impairment of endocrine, haematological, musculoskeletal, renal, respiratory and vascular systems, which influence morbidity and mortality.
authors.affiliation: Specialist Registrar in Cardiology in the Department of Cardiology Doncaster Royal Infimary, Doncaster DN2 5LT.
authors.forename: David
authors.initials: D
authors.lastname: Warriner
authors.affiliation: Consultant Electrophysiologist, Department of Cardiology, Northern General Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield.
authors.forename: Paul
authors.initials: P
authors.lastname: Sheridan
authors.affiliation: Professor of Physiological Modelling in the Medical Physics Group, Department of Cardiovascular Science, The Medical School, University of Sheffield, Sheffield.
authors.forename: Patricia
authors.initials: P
authors.lastname: Lawford
mesh_terms: D004703:Endocrine System / Q000503:physiopathology; D006333:Heart Failure / Q000150:complications / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D007668:Kidney / Q000378:metabolism / Q000503:physiopathology; D009102:Multiple Organ Failure / Q000209:etiology / Q000276:immunology / Q000378:metabolism / Q000503:physiopathology; D009141:Musculoskeletal System / Q000503:physiopathology; D010281:Parathyroid Hormone / Q000097:blood; D012137:Respiratory System / Q000503:physiopathology; D014527:Uric Acid / Q000097:blood
chemical_list: D010281:Parathyroid Hormone; D014527:Uric Acid