title: Flowing through the CRISPR-CAScade: Will genome editing boost cell therapies?
abstract: Recent years have seen great advancements in genome editing technologies, allowing for efficient and specific targeting of DNA sequences into the genome. In parallel, advancements in stem cell research, and especially the ability to induce pluripotency in somatic cells, have brought stem cell-derived therapies closer to the clinic. In this commentary, I envision how groundbreaking genome editing technologies will influence stem cell biology research, paving the way to regenerative medicine with genetically engineered cells.
authors.affiliation: Stem Cell Unit, Department of Genetics, Silberman Institute of Life Sciences, The Hebrew University, Jerusalem, 91904 Israel.
authors.forename: Uri
authors.initials: U
authors.lastname: Ben-David
keywords: Cell therapy; Genome editing; Stem cells