title: Delayed Presentation of Ureteropelvic Junction Obstruction and Loss of Renal Function After Initially Mild (SFU Grade 1-2) Hydronephrosis.
abstract: We report 4 pediatric cases of ureteropelvic junction obstruction involving delayed progression of initially mild postnatal hydronephrosis. All 4 children became symptomatic; however, 3 already had a substantial decrement of ipsilateral kidney function by the time of diagnosis. Two of these 3 patients had previous renal scintigraphy demonstrating normal differential function. We caution that counseling regarding hydronephrosis should emphasize the importance of prompt re-evaluation for any symptoms potentially referable to delayed presentation of ureteropelvic junction obstruction, irrespective of initial hydronephrosis grade. Future studies are needed to determine the optimal follow-up regimen for conservative management of hydronephrosis.
authors.affiliation: Division of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL.
authors.forename: Diana K
authors.initials: DK
authors.lastname: Bowen
authors.affiliation: Division of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL.
authors.forename: Elizabeth B
authors.initials: EB
authors.lastname: Yerkes
authors.affiliation: Division of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL.
authors.forename: Bruce W
authors.initials: BW
authors.lastname: Lindgren
authors.affiliation: Division of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL.
authors.forename: Edward M
authors.initials: EM
authors.lastname: Gong
authors.affiliation: Division of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL. Electronic address: mfaasse@sbcglobal.net.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Faasse
mesh_terms: D057210:Delayed Diagnosis; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging / Q000379:methods*; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D006869:Hydronephrosis / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D007223:Infant; D007231:Infant, Newborn; D007677:Kidney Function Tests; D008297:Male; D014517:Ureteral Obstruction / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology