title: Clinical curative effect of percutaneous vertebroplasty combined with 125I-seed implantation in treating spinal metastatic tumor.
abstract: This paper selected and studied 15 in-hospital patients to analyze and discuss the clinical curative effect of percutaneous vertebroplasty (PVP) combined with (125)I-seed implantation in treating spinal metastatic tumor. The evaluation of clinical curative effects was based on the observation of several factors, namely recovery conditions of vertebral body's leading edge and middle section before and after surgery, improvements of kyphosis Cobb angle, visual analog scale (VAS), and Barthel Index (BI). The paper found significant difference between preoperative VAS and postoperative VAS, and the same situation occurred to BI. However, compared to the loss rate of vertebral body's leading edge and middle section and the improvement of Cobb angle before operative, postoperative loss rate and Cobb angle did not show statistical difference. Thus the conclusion is that PVP combined with (125)I-seed implantation is a minimally invasive surgery for effectively treating spinal metastatic tumor, which does well in rapidly releasing pains, improving patients' daily life activities and life qualities.
authors.affiliation: Department of Orthopaedics, Laiyang Central Hospital, Yantai City, Shandong Province, China.
authors.forename: Shixin
authors.initials: S
authors.lastname: Wang
authors.affiliation: Department of Orthopaedics, Laiyang Central Hospital, Yantai City, Shandong Province, China.
authors.forename: Guohua
authors.initials: G
authors.lastname: Shi
authors.affiliation: Department of Orthopaedics, Laiyang Central Hospital, Yantai City, Shandong Province, China.
authors.forename: Xianqing
authors.initials: X
authors.lastname: Meng
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D001416:Back Pain / Q000209:etiology / Q000523:psychology / Q000628:therapy; D001918:Brachytherapy / Q000009:adverse effects; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects / Q000627:therapeutic use*; D008159:Lumbar Vertebrae / Q000503:physiopathology / Q000528:radiation effects / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011788:Quality of Life; D019275:Radiopharmaceuticals / Q000009:adverse effects / Q000627:therapeutic use*; D018714:Radiotherapy, Adjuvant; D020127:Recovery of Function; D013125:Spinal Neoplasms / Q000150:complications / Q000503:physiopathology / Q000523:psychology / Q000556:secondary / Q000628:therapy*; D013904:Thoracic Vertebrae / Q000503:physiopathology / Q000528:radiation effects / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome; D054854:Vertebroplasty / Q000009:adverse effects / Q000379:methods*
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals