title: A comparison of oxycodone and fentanyl in intravenous patient-controlled analgesia after laparoscopic hysterectomy.
abstract: BACKGROUND
  We planned to compare the effect of intravenous oxycodone and fentanyl on post-operative pain after laparoscopic hysterectomy.
  
  
  METHODS
  We examined 60 patients were randomized to postoperative pain treatment with either oxycodone (n = 30, Group O) or fentanyl (n = 30, Group F). The patients received 10 mg oxycodone/100 µg fentanyl with ketorolac 30 mg before the end of anesthesia and then continued with patient-controlled analgesia for 48 h postoperatively.
  
  
  RESULTS
  The accumulated oxycodone consumption was less than fentanyl during 8, 24 and 48 h postoperatively. Numeric rating score of Group O showed significantly lower than that of Group F during 30 min, 2, 4, 8 and 24 h postoperatively. The incidences of adverse reactions were similar in the two groups, though the incidence of nausea was higher in the Group O during the 24 and 48 h postoperative period.
  
  
  CONCLUSIONS
  Oxycodone IV-PCA was more advantageous than fentanyl IV-PCA for laparoscopic hysterectomy in view of accumulated oxycodone consumption, pain control and cost beneficial effect. However, patient satisfaction was not good in the group O compared to group F.
authors.affiliation: Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Nan-Seol
authors.initials: NS
authors.lastname: Kim
authors.affiliation: Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Kyu Sik
authors.initials: KS
authors.lastname: Kang
authors.affiliation: Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Sie Hyeon
authors.initials: SH
authors.lastname: Yoo
authors.affiliation: Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Jin Hun
authors.initials: JH
authors.lastname: Chung
authors.affiliation: Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Ji-Won
authors.initials: JW
authors.lastname: Chung
authors.affiliation: Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Yonghan
authors.initials: Y
authors.lastname: Seo
authors.affiliation: Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Ho-Soon
authors.initials: HS
authors.lastname: Chung
authors.affiliation: Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Hye-Rim
authors.initials: HR
authors.lastname: Jeon
authors.affiliation: Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Hyung Youn
authors.initials: HY
authors.lastname: Gong
authors.affiliation: Department of Anesthesiology and Pain Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Hyun-Young
authors.initials: HY
authors.lastname: Lee
authors.affiliation: Department of Obstetrics and Gynecology, Soonchunhyang University Cheonan Hospital, Soonchunhyang Univertisy College of Medicine, Cheonan, Korea.
authors.forename: Seong-Taek
authors.initials: ST
authors.lastname: Mun
keywords: Fentanyl; Oxycodone; Postoperative pain