title: Well-Defined and Robust Rhodium Catalysts for the Hydroacylation of Terminal and Internal Alkenes.
abstract: A Rh-catalyst system based on the asymmetric ligand (t)Bu2PCH2P(o-C6H4OMe)2 is reported that allows for the hydroacylation of challenging internal alkenes with β-substituted aldehydes. Mechanistic studies point to the stabilizing role of both excess alkene and the OMe-group.
authors.affiliation: Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK).
authors.forename: Amparo
authors.initials: A
authors.lastname: Prades
authors.affiliation: Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK).
authors.forename: Maitane
authors.initials: M
authors.lastname: Fernández
authors.affiliation: Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK).
authors.forename: Sebastian D
authors.initials: SD
authors.lastname: Pike
authors.affiliation: Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK). michael.willis@chem.ox.ac.uk.
authors.forename: Michael C
authors.initials: MC
authors.lastname: Willis
authors.affiliation: Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK). andrew.weller@chem.ox.ac.uk.
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Weller
keywords: catalysis; hydroacylation; phosphine; rhodium