title: A step toward simplified detection of serum albumin on SDS-PAGE using an environment-sensitive flavone sensor.
abstract: In this study, we report a series of novel flavone-based sensors that exhibit a superior fluorescence response when interacting with serum albumin in real serum samples and in acrylamide gels. The detection limit of probe 4 for serum albumin solution is 0.09 μg mL(-1), and the detectable volume for monkey serum reaches as low as 0.03 μL.
authors.affiliation: Department of Chemistry, University of Akron, Akron, Ohio 44325, USA. yp5@uakron.edu.
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Yi
authors.initials: Y
authors.lastname: Pang
authors.forename: Rachida
authors.initials: R
authors.lastname: Bouhenni
authors.forename: Ernest
authors.initials: E
authors.lastname: Duah
authors.forename: Sailaja
authors.initials: S
authors.lastname: Paruchuri
authors.forename: Lucas
authors.initials: L
authors.lastname: McDonald
mesh_terms: D004591:Electrophoresis, Polyacrylamide Gel; D047309:Flavones / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D012709:Serum Albumin / Q000032:analysis*
chemical_list: D047309:Flavones; D005456:Fluorescent Dyes; D012709:Serum Albumin; C043562:flavone