title: Comparison between Platelet-Rich Plasma and Autologous Iliac Grafts for Tibial Osteotomy.
abstract: OBJECTIVE
  Platelet-rich plasma (PRP) has the capacity to improve the bone-healing process. The aim of this pilot study was to investigate the occurrence of bone healing and the time taken to achieve this in patients submitted to medial opening wedge high tibial osteotomy (MOWHTO), comparing platelet-rich plasma with bone marrow aspirate to autologous iliac graft.
  
  
  METHODS
  Twenty-five patients who underwent tibial osteotomy were randomly divided into 2 groups: a control group, which received autologous iliac grafts (14 patients), and a study group, which received a compound of PRP and bone marrow aspirate (11 patients).
  
  
  RESULTS
  The bone-healing rates achieved were 100% in the control group and 91% in the study group. There was no difference in the time taken to achieve bone healing between the groups.
  
  
  CONCLUSIONS
  The use of a combination of PRP and bone marrow aspirate, as a bone substitute, did not demonstrate any advantage over the use of an autologous iliac graft in MOWHTO.
authors.affiliation: Hospital das Clínicas, School of Medicine of the University of São Paulo, São Paulo, Brazil.
authors.forename: Caio Oliveira
authors.initials: CO
authors.lastname: D'Elia
authors.affiliation: Hospital das Clínicas, School of Medicine of the University of São Paulo, São Paulo, Brazil.
authors.forename: Márcia Uchôa
authors.initials: MU
authors.lastname: de Rezende
authors.affiliation: Instituto Vita, São Paulo, Brazil.
authors.forename: Alexandre Carneiro
authors.initials: AC
authors.lastname: Bitar
authors.affiliation: Hospital das Clínicas, School of Medicine of the University of São Paulo, São Paulo, Brazil.
authors.forename: Nelson
authors.initials: N
authors.lastname: Tatsui
authors.affiliation: Hospital das Clínicas, School of Medicine of the University of São Paulo, São Paulo, Brazil.
authors.forename: José Ricardo
authors.initials: JR
authors.lastname: Pécora
authors.affiliation: Hospital das Clínicas, School of Medicine of the University of São Paulo, São Paulo, Brazil.
authors.forename: Arnaldo José
authors.initials: AJ
authors.lastname: Hernandez
authors.affiliation: Hospital das Clínicas, School of Medicine of the University of São Paulo, São Paulo, Brazil.
authors.forename: Gilberto Luis
authors.initials: GL
authors.lastname: Camanho
keywords: bone marrow; bone substitutes; knee; osteotomy; platelet-rich plasma