title: Cyclic α-Alkoxyphosphonium Salts from (2-(Diphenylphosphino)phenyl)methanol and Aldehydes and Their Application in Synthesis of Vinyl Ethers and Ketones via Wittig Olefination.
abstract: Cyclic α-alkoxyphosphonium salts have been synthesized from (2-(diphenylphosphino)phenyl)methanol and aldehydes in 36-89% yields. These phosphonium salts are bench-stable solids and undergo Wittig olefination with aldehydes under basic conditions (K2CO3 or t-BuOK) to form benzylic vinyl ethers, which are readily hydrolyzed to 1,2-disubstituted ethanones under acidic conditions. The formation mechanism of these phosphonium salts via hemiacetal is also proposed.
authors.affiliation: Department of Chemistry, Tianjin University, 92 Weijin Road, Tianjin 300072, P. R. China.
authors.forename: Wenhua
authors.initials: W
authors.lastname: Huang
authors.affiliation: Department of Chemistry, Tianjin University, 92 Weijin Road, Tianjin 300072, P. R. China.
authors.forename: Hong-Ying
authors.initials: HY
authors.lastname: Rong
authors.affiliation: Department of Chemistry, Tianjin University, 92 Weijin Road, Tianjin 300072, P. R. China.
authors.forename: Jie
authors.initials: J
authors.lastname: Xu