title: Successful treatment with infliximab for refractory para-ileostomal ulceration in a patient with Behҫet's disease.
abstract: Behҫet's disease (BD) is a chronic disorder involving multiple organ systems including the small and large intestines. A 46-year-old female diagnosed with intestinal BD presented with ileocecal perforation and diffuse peritonitis and subsequently underwent ileocolic resection with ileostomy. After surgery, she suffered from refractory para-ileostomal ulceration associated with BD. Most importantly, however, treatment with infliximab was significantly effective in healing the ulceration. This is the first report of para-ileostomal ulceration associated with BD successfully treated with infliximab, suggesting the possible use of infliximab as a therapeutic option for para-stomal ulcers related to BD.
authors.affiliation: Department of Gastroenterology, Akita University Hospital, Akita, Japan.
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Ishioka
authors.forename: Kengo
authors.initials: K
authors.lastname: Onochi
authors.forename: Yusato
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sawaguchi
authors.forename: Natsumi
authors.initials: N
authors.lastname: Hatakeyama
authors.forename: Shigeto
authors.initials: S
authors.lastname: Koizumi
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Matsuhashi
authors.forename: Mario
authors.initials: M
authors.lastname: Jin
authors.forename: Hirohide
authors.initials: H
authors.lastname: Ohnishi
mesh_terms: D001528:Behcet Syndrome / Q000601:surgery*; D005260:Female; D006801:Humans; D007081:Ileostomy / Q000009:adverse effects*; D000069285:Infliximab / Q000627:therapeutic use*; D007410:Intestinal Diseases / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D014456:Ulcer / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000069285:Infliximab