title: Copper-catalyzed efficient direct amidation of 2-methylquinolines with amines.
abstract: A novel Cu-catalyzed direct amidation of 2-methylquinolines with amines is described. This method afforded an efficient approach for the synthesis of biologically important aromatic amides from readily available coupling partners using molecular oxygen as the oxidant.
authors.affiliation: Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan 411105, China. gjdeng@xtu.edu.cn.
authors.forename: Hao
authors.initials: H
authors.lastname: Xie
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Liao
authors.forename: Shuqing
authors.initials: S
authors.lastname: Chen
authors.forename: Ya
authors.initials: Y
authors.lastname: Chen
authors.forename: Guo-Jun
authors.initials: GJ
authors.lastname: Deng
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis* / Q000737:chemistry; D016877:Oxidants / Q000737:chemistry; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D011798:Quinaldines / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000577:Amides; D000588:Amines; D006841:Hydrocarbons, Aromatic; D016877:Oxidants; D011798:Quinaldines; D003300:Copper; C037073:2-methylquinoline; D010100:Oxygen