title: A Case of Mediastinal Granular Cell Tumor with Horner's Syndrome.
abstract: Granular cell tumor (GCT) is found in various organs but is rare in the mediastinum. We report a case of mediastinal GCT in a 19-year-old woman who presented with left ptosis and miosis. CT and MRI revealed a 29-mm well-circumscribed tumor located close to the first thoracic vertebra with features suggesting a neurogenic tumor. The tumor was completely excised using single-port video-assisted thoracoscopic surgery. Histopathological and immunohistochemical analysis revealed that the tumor was a benign GCT. Postoperatively, left ptosis and miosis had improved slightly. To our knowledge, this is the first report regarding mediastinal GCT presenting with preoperative Horner's syndrome.
authors.affiliation: Center of Chest Medicine and Surgery, Ehime University, Toon, Ehime, Japan.
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Shikatani
authors.forename: Mikio
authors.initials: M
authors.lastname: Okazaki
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Sakao
authors.forename: Shungo
authors.initials: S
authors.lastname: Yukumi
authors.forename: Hisayuki
authors.initials: H
authors.lastname: Shigematsu
authors.forename: Sohei
authors.initials: S
authors.lastname: Kitazawa
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Sano
mesh_terms: D005260:Female; D005870:Giant Cell Tumors / Q000150:complications / Q000175:diagnosis*; D006732:Horner Syndrome / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008479:Mediastinal Neoplasms / Q000150:complications / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D055815:Young Adult