title: [The anti-synthetases syndrome: diagnostic and treatments].
abstract: The anti-synthetases syndrome is a rare disease with a specific constellation of clinical symptoms present in a subset of patients with inflammatory myopathy. Besides constitutional symptoms and myositis, it is associated with mechanic's hands, Raynaud phenomenon, and non-erosive arthritis. This syndrome is characterized by the presence of one of eight auto-antibodies to aminoacyl-transfer ribonucleic acid synthetase enzymes in the serum. Interstitial lung disease is more frequent in this subpopulation of inflammatory myopathy and worsens the patient's prognosis.
authors.forename: D
authors.initials: D
authors.lastname: Allali
authors.forename: J D
authors.initials: JD
authors.lastname: Seebach
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000276:immunology*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D009220:Myositis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D011379:Prognosis
chemical_list: D001323:Autoantibodies