title: Incorporating Sex as a Variable in Preclinical Neuropsychiatric Research.
abstract: In an effort to increase applicability of preclinical research to both men and women, the National Institute of Health is anticipated to put forth guidelines for the incorporation of sex as a variable in animal studies. Common myths and perceived barriers to the inclusion of females in neuroscience research are discussed and a roadmap for implementation provided. Accounting for sex as a variable does not require studying sex differences and is easier to implement than generally assumed.
authors.affiliation: Departments of Pharmacology, Physiology and Psychiatry, University of Maryland School of Medicine, Baltimore, MD mmccarth@umaryland.edu.
authors.forename: Margaret M
authors.initials: MM
authors.lastname: McCarthy
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000592:standards*; D005260:Female; D008297:Male; D023421:Models, Animal; D012107:Research Design / Q000592:standards*; D012727:Sex Characteristics; D012737:Sex Factors
keywords: behavior; hormones; sex differences