title: Serious anaphylactic shock induced by hemocoagulase agkistrodon during anesthesia in a 5-year-old child.
abstract: We report a case of serious anaphylactic shock in a 5-year-old child undergoing scheduled surgery blank space of a right femoral intramedullary nail removal. The boy had undergone right femoral elastic intramedullary nail fixation surgery 14 months prior, but had no history of allergies. Within 5 minutes of intravenous bonus injection of hemocoagulase agkistrodon (HCA) 1 unit, a widespread transient diffuse erythema was seen on the front of his chest. After 20 minutes, sudden, profound cardiovascular collapse occurred. The child was treated effectively and sent to a ward 5 hours later. In this period, he received intravenously infused 200 ml hydroxyethyl starch solution and epinephrine at a rate of 0.05-0.01 μg kg(-1) min(-1). Total amount of dexamethasone sodium phosphate 14 mg was used. To the best of our knowledge, few case reports of HCA-induced anaphylactic shock in children exist. Our report will, therefore, increase awareness of the allergic potential of HCA among pediatric anesthesiologists.
authors.affiliation: Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangzhou, P. R. China.
authors.forename: Ying-Yi
authors.initials: YY
authors.lastname: Xu
authors.affiliation: Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangzhou, P. R. China.
authors.forename: Bi-Lian
authors.initials: BL
authors.lastname: Li
authors.affiliation: Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangzhou, P. R. China.
authors.forename: Yu-Lin
authors.initials: YL
authors.lastname: Jin
authors.affiliation: Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangzhou, P. R. China.
authors.forename: Zi-Xin
authors.initials: ZX
authors.lastname: Wang
authors.affiliation: Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangzhou, P. R. China.
authors.forename: Xing-Rong
authors.initials: XR
authors.lastname: Song
authors.affiliation: Department of Anesthesiology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University Guangzhou, P. R. China.
authors.forename: Jin
authors.initials: J
authors.lastname: Ni
keywords: Hemocoagulase agkistrodon; anaphylactic shock; children; complications