title: An Effective Quality Control of Pharmacologically Active Volatiles of Houttuynia cordata Thunb by Fast Gas Chromatography-Surface Acoustic Wave Sensor.
abstract: Fast gas chromatography-surface acoustic wave sensor (GC/SAW) has been applied for the detection of the pharmacological volatiles emanated from Houttuynia cordata Thunb which is from South Korea. H. cordata Thunb with unpleasant and fishy odors shows a variety of pharmacological activities such as anti-microbial, anti-inflammatory, anti-cancer, and insect repellent. The aim of this study is to show a novel quality control by GC/SAW methodology for the discrimination of the three different parts of the plant such as leaves, aerial stems, and underground stems for H. cordata Thunb. Sixteen compounds were identified. β-Myrcene, cis-ocimene and decanal are the dominant volatiles for leaves (71.0%) and aerial stems (50.1%). While, monoterpenes (74.6%) are the dominant volatiles for underground stems. 2-Undecanone (1.3%) and lauraldehyde (3.5%) were found to be the characteristic components for leaves. Each part of the plant has its own characteristic fragrance pattern owing to its individual chemical compositions. Moreover, its individual characteristic fragrance patterns are conducive to discrimination of the three different parts of the plant. Consequently, fast GC/SAW can be a useful analytical method for quality control of the different parts of the plant with pharmacological volatiles as it provides second unit analysis, a simple and fragrant pattern recognition.
authors.affiliation: Herbal Medicine Analytical Laboratory, KOSMO NF Co., Ltd., 28-8 Seongan-ro 13Gil, Gangdong-Gu, Seoul 134-849, Korea. syohkosmo62@hanmail.net.|College of Science, Sejong University, 209 Neungdong-ro, Gwangjin-Gu, Seoul 143-747, Korea . syohkosmo62@hanmail.net.
authors.forename: Se Yeon
authors.initials: SY
authors.lastname: Oh
mesh_terms: D000080462:Acyclic Monoterpenes; D000447:Aldehydes / Q000302:isolation & purification; D000475:Alkenes / Q000302:isolation & purification; D002849:Chromatography, Gas / Q000295:instrumentation* / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D052859:Houttuynia / Q000737:chemistry*; D007659:Ketones / Q000302:isolation & purification; D039821:Monoterpenes / Q000302:isolation & purification; D009812:Odorants / Q000032:analysis*; D018515:Plant Leaves / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*; D011786:Quality Control; D013016:Sound; D055549:Volatile Organic Compounds / Q000302:isolation & purification*
chemical_list: D000080462:Acyclic Monoterpenes; D000447:Aldehydes; D000475:Alkenes; D004365:Drugs, Chinese Herbal; C442781:Houttuynia cordata extract; D007659:Ketones; D039821:Monoterpenes; D055549:Volatile Organic Compounds; C008574:beta-myrcene; C021170:decanaldehyde; C477141:alpha-ocimene; C526928:undecan-2-one
keywords: Houttuynia cordata Thunb; fragrance pattern recognition; gas chromatography/surface acoustic wave sensor; quality control