title: Enantio- and diastereoselective asymmetric allylic alkylation catalyzed by a planar-chiral cyclopentadienyl ruthenium complex.
abstract: We report asymmetric allylic alkylation of allylic chloride with β-diketones as the prochiral carbon nucleophiles using a planar-chiral Cp'Ru catalyst. The reaction proceeds under mild conditions; the resulting chiral products containing vicinal tertiary stereocenters are obtained with high regio-, diastereo-, and enantioselectivities. These chiral products can then be transformed into a chiral diol by controlling the four stereocentres.
authors.affiliation: Department of Macromolecular Science, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan. naokou@chem.sci.osaka-u.ac.jp onitsuka@chem.sci.osaka-u.ac.jp.
authors.forename: Naoya
authors.initials: N
authors.lastname: Kanbayashi
authors.forename: Kazuki
authors.initials: K
authors.lastname: Hosoda
authors.forename: Masanori
authors.initials: M
authors.lastname: Kato
authors.forename: Koichiro
authors.initials: K
authors.lastname: Takii
authors.forename: Taka-aki
authors.initials: TA
authors.lastname: Okamura
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Onitsuka