title: The Basic Principles of FDG-PET/CT Imaging.
abstract: Positron emission tomography (PET) imaging with 2-[(18)F]fluoro-2-deoxy-D-glucose (FDG) forms the basis of molecular imaging. FDG-PET imaging is a multidisciplinary undertaking that requires close interdisciplinary collaboration in a broad team comprising physicians, technologists, secretaries, radio-chemists, hospital physicists, molecular biologists, engineers, and cyclotron technicians. The aim of this review is to provide a brief overview of important basic issues and considerations pivotal to successful patient examinations, including basic physics, instrumentation, radiochemistry, molecular and cell biology, patient preparation, normal distribution of tracer, and potential interpretive pitfalls.
authors.affiliation: Radiation Medicine Center, Bhabha Atomic Research Centre, Tata Memorial Hospital Annexe, Jerbai Wadia Road, Parel, Mumbai 400012, India.
authors.forename: Sandip
authors.initials: S
authors.lastname: Basu
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, Soender Boulevard 29, Odense 5000, Denmark. Electronic address: soeren.hess@rsyd.dk.
authors.forename: Søren
authors.initials: S
authors.lastname: Hess
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, Soender Boulevard 29, Odense 5000, Denmark.
authors.forename: Poul-Erik
authors.initials: PE
authors.lastname: Nielsen Braad
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, Soender Boulevard 29, Odense 5000, Denmark.
authors.forename: Birgitte Brinkmann
authors.initials: BB
authors.lastname: Olsen
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, Soender Boulevard 29, Odense 5000, Denmark.
authors.forename: Signe
authors.initials: S
authors.lastname: Inglev
authors.affiliation: Department of Nuclear Medicine, Odense University Hospital, Soender Boulevard 29, Odense 5000, Denmark.
authors.forename: Poul Flemming
authors.initials: PF
authors.lastname: Høilund-Carlsen
mesh_terms: D019788:Fluorodeoxyglucose F18; D006801:Humans; D064847:Multimodal Imaging; D010825:Physics; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: FDG; Fluorodeoxyglucose; History; Instrumentation; PET/CT; Physics; Positron emission tomography/computed tomography; Radiochemistry