title: Molecular Pathology Informatics.
abstract: Molecular informatics (MI) is an evolving discipline that will support the dynamic landscape of molecular pathology and personalized medicine. MI provides a fertile ground for development of clinical solutions to bridge the gap between clinical informatics and bioinformatics. Rapid adoption of next generation sequencing (NGS) in the clinical arena has triggered major endeavors in MI that are expected to bring a paradigm shift in the practice of pathology. This brief review presents a broad overview of various aspects of MI, particularly in the context of NGS based testing.
authors.affiliation: Department of Pathology, Molecular and Genomic Pathology, University of Pittsburgh Medical Center, 3477 Euler way, Pittsburgh, PA 15213, USA. Electronic address: roys@upmc.edu.
authors.forename: Somak
authors.initials: S
authors.lastname: Roy
mesh_terms: D000067917:Cloud Computing; D019295:Computational Biology; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods; D008490:Medical Informatics; D057089:Pathology, Molecular / Q000379:methods*; D057285:Precision Medicine / Q000379:methods; D017422:Sequence Analysis, DNA
keywords: Bioinformatics; Clinical informatics; Molecular informatics; Next-generation sequencing