title: Diagnostic Fine-Needle Aspiration Biopsy for Iris Melanoma.
abstract: OBJECTIVE
  The aim of this study was to describe a case of iris melanoma diagnosed by fine-needle aspiration biopsy (FNAB) with review of the literature.
  
  
  METHODS
  This study presents a case report and review of the literature.
  
  
  METHODS
  A 76-year-old white man presented with iris melanoma arising from preexisting iris nevus that was confirmed cytologically by a transcorneal FNAB.
  
  
  RESULTS
  A pigmented lesion on the left iris extending from 3 to 8:30 o'clock, from the iris root to the pupillary margin without ectropion uveae, was biopsied through 1-mm clear corneal incision. A short 25-gauge needle was inserted into the tumor while applying aspiration, and 10-0 suture was used to close the wound. Cytopathology confirmed the presence of spindle-shaped cells with conspicuous cytoplasmic melanin and nuclear atypia consistent with the diagnosis of melanoma. There were no intraoperative or postoperative complications. The patient was subsequently treated with radiation plaque brachytherapy.
  
  
  CONCLUSIONS
  Although indicated only in minority of cases, it is important to consider FNAB for the diagnosis and management of iris lesions.
authors.affiliation: From the *Cole Eye Institute and †Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH.
authors.forename: Rahul
authors.initials: R
authors.lastname: Gokhale
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Medina
authors.forename: Charles V
authors.initials: CV
authors.lastname: Biscotti
authors.forename: Arun D
authors.initials: AD
authors.lastname: Singh
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D006801:Humans; D007498:Iris / Q000473:pathology; D015811:Iris Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology; D009508:Nevus, Pigmented / Q000175:diagnosis* / Q000473:pathology; D014604:Uveal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D000098943:Uveal Melanoma