title: Molecular and Cellular Therapies: New challenges and opportunities.
abstract: Gene therapy is suggested to be one of the most specific and efficient modulations for gene deficient diseases and extended to other diseases like cancer and inflammation, even though there are still challenges to be faced, such as specific and selective delivery, minimal to no toxicity, efficient metabolism, simplicity, and measurable efficiency. It is important to identify and validate drug-able disease-specific targets for molecular and cellular therapies, while it is equally important to have disease biomarkers to trace and define the biological effects of molecular and cellular therapies. The importance and significance of allostery in molecular and cellular therapies and "allosteric disease", "allosteric effect", and "allosteric drug" should be more carefully examined and validated. Cell therapy has been attracting an increasing amount of consideration in the development of new treatments for diseases. Molecular and Cellular Therapies (MCT) is a new, open-access journal, devoted to molecular mechanisms, preclinical and clinical research and development of gene-, peptide-, protein-, and cell-based therapies.
authors.affiliation: Shanghai Institute of Respiratory Diseases; Department of Respiratory Medicine, Fudan University Zhongshan Hospital, Shanghai, Sweden ; Institute of Clinical Science, Lund University, Lund, Sweden.
authors.forename: Xiangdong
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Cell Research & Immunology, Laboratory of NanoMedicine, and the center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Dan
authors.initials: D
authors.lastname: Peer
authors.affiliation: Department of Pediatrics, University of Florida, Children Health Research Institute, Gainesville, FL USA.
authors.forename: Bryon
authors.initials: B
authors.lastname: Petersen
keywords: Cellular therapy; Disease; Journal; Molecular therapy