title: Long-term patterns of safety and efficacy of bleeding prophylaxis with turoctocog alfa (NovoEight(®) ) in previously treated patients with severe haemophilia A: interim results of the guardian(™) 2 extension trial.
authors.affiliation: IHTC 'Claudio L.P. Correa', INCT do Sangue Hemocentro UNICAMP, University of Campinas, Sao Paulo, Brazil.
authors.forename: M
authors.initials: M
authors.lastname: Ozelo
authors.affiliation: National Hemophilia Center, Chaim Sheba Medical Center, Tel Aviv University, Tel Aviv, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Misgav
authors.affiliation: National Blood Centre, Kuala Lumpur, Malaysia.
authors.forename: F
authors.initials: F
authors.lastname: Abdul Karim
authors.affiliation: The University of Iowa Carver College of Medicine, Iowa City, IA, USA.
authors.forename: S R
authors.initials: SR
authors.lastname: Lentz
authors.affiliation: Haematology Department, Hospital Universitario La Paz, Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Martin-Salces
authors.affiliation: Novo Nordisk A/S, Soeborg, Denmark.
authors.forename: I
authors.initials: I
authors.lastname: Matytsina
authors.affiliation: Novo Nordisk A/S, Soeborg, Denmark.
authors.forename: T
authors.initials: T
authors.lastname: Saugstrup
authors.affiliation: Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Maggiore Hospital Policlinico, Milan, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Santagostino
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D005169:Factor VIII / Q000009:adverse effects* / Q000627:therapeutic use*; D006467:Hemophilia A / Q000150:complications / Q000188:drug therapy*; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control*; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008875:Middle Aged; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D006490:Hemostatics; C577506:recombinant factor VIII N8; D005169:Factor VIII