title: Is there any relationship between RDW levels and atrial fibrillation in hypertensive patient?
abstract: BACKGROUND
  Atrial fibrillation (AF) is the most common cardiac arrhythmia and increases the risk of stroke and death. Patients with hypertensive have an increased risk of developing atrial fibrillation. RDW (Red blood cell distribution width) levels are elevated in cardiovascular disorders including heart failure, stable coronary disease, acute coronary syndrome, slow coronary flow and stroke.
  
  
  OBJECTIVE
  We aimed to investigate the relation between RDW and AF in patients with hypertensive.
  
  
  METHODS
  We retrospectively examined 126 consecutive hypertensive patients (63 hypertensive patients with AF and 63 hypertensive patients without AF matched with age and sex.
  
  
  RESULTS
  The mean age of the study population was 71,09± 8,50 (af group) and 70,97±8,24 (non-af group) years. RDW level was different among patients with atrial fibrillation and without atrial fibrillation.(15,13±1,58 and 14,05±1,15 p<001) . Logistic regression analysis showed that RDW and left atrial dimension were only independently risk factory associated with atrial fibrillation. (Rdw odds ratio:1,846 CI; 1,221-2,793 p<0,05). Roc curve analyses were applied to determine the cut-off point. Cut-off point was at 14,195 and Sensitive, specificity was %71,4, %56 respectively.
  
  
  CONCLUSIONS
  RDW levels were higher in hypertensive patients with atrial fibrillation. An increased RDW level in the patient with hypertension may alert physician on developing or presence of atrial fibrillation.
authors.affiliation: Department of Cardiology, Bozok university, Yozgat Turkey.
authors.forename: Savas
authors.initials: S
authors.lastname: Sarikaya
authors.affiliation: Department of Internal Medicine, Gaziosmanpaşa university, Tokat Turkey.
authors.forename: Şafak
authors.initials: Ş
authors.lastname: Şahin
authors.affiliation: Department of internal medicine, Bozok university, Yozgat Turkey.
authors.forename: Lütfi
authors.initials: L
authors.lastname: Akyol
authors.affiliation: Department of internal medicine, Bozok university, Yozgat Turkey.
authors.forename: Elif
authors.initials: E
authors.lastname: Börekçi
authors.affiliation: Department of cardiovascular surgery, Bozok university, Yozgat Turkey.
authors.forename: Yunus Keser
authors.initials: YK
authors.lastname: Yilmaz
authors.affiliation: Department of Cardiology, Gaziosmanpaşa university, Tokat Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Altunkaş
authors.affiliation: Department of Cardiology, Gaziosmanpaşa university, Tokat Turkey.
authors.forename: Kayihan
authors.initials: K
authors.lastname: Karaman
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure / Q000502:physiology; D015150:Echocardiography, Doppler; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012044:Regression Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000150:complications
chemical_list: D015415:Biomarkers
keywords: atrial fibrillation; hypertension; red blood cell distribution width