title: Spectral-Domain Optical Coherence Tomography of Presumed Solitary Circumscribed Retinal Astrocytic Proliferation Versus Astrocytic Hamartoma.
abstract: The retinal tumor provisionally referred to as presumed solitary circumscribed retinal astrocytic proliferation (PSCRAP) is a rare, benign lesion of unknown pathogenesis and histopathology. The authors present a case of PSCRAP that was analyzed with spectral-domain optical coherence tomography (OCT), which demonstrated a demarcation between the mass and the retinal nerve fiber layer. This finding stands in contrast to previous descriptions using time-domain OCT, suggesting that this tumor may originate from mid-retinal layers rather than the nerve fiber layer. In addition, the OCT of PSCRAP is distinct from that of astrocytic hamartoma associated with tuberous sclerosis complex.
authors.forename: Stephen G
authors.initials: SG
authors.lastname: Schwartz
authors.forename: J William
authors.initials: JW
authors.lastname: Harbour
mesh_terms: D001253:Astrocytes / Q000473:pathology*; D049109:Cell Proliferation; D003937:Diagnosis, Differential; D005260:Female; D006222:Hamartoma / Q000175:diagnosis*; D006801:Humans; D008875:Middle Aged; D012164:Retinal Diseases / Q000175:diagnosis*; D055351:Retinal Neurons / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014402:Tuberous Sclerosis / Q000150:complications; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult