title: [First synchronous liver resection as a part of cytoreductive surgery, peritonectomy and HIPEC in Croatia--case report].
abstract: We present a case of a 37-year-old female, with large adenocarcinoma of transverse colon, and metastases in spleen, liver, peritoneum, greater omentum, gall bladder and right adnexa. She was transferred to our Hospital, and extensive elective cytoreductive surgery with intraabdominal hyperthermal chemotherapy (HIPEC) was performed. Couple of months later, she was operated on for a newly evidenced secondary nodus in liver segment VII, and metastasectomy was performed. Throughout entire postoperative period she was receiving cyclic chemotherapy. At this point, 2 years from the first operation, she was without evidenced recurrence of the disease. Aggressive cytoreductive surgery with multiorgan resection, peritonectomy, HIPEC and adjuvant chemotherapy which was proved to be a feasible option in some patients, with synchronous liver resection (LR) proved to be feasible and beneficial for patients with three or fewer liver metastases. This is the first liver resection included in usually performed cytoreductive surgery and HIPEC in Croatia.
authors.forename: Ana Majsec
authors.initials: AM
authors.lastname: Budak
authors.forename: Mate
authors.initials: M
authors.lastname: Škegro
authors.forename: Mate
authors.initials: M
authors.lastname: Majerović
authors.forename: Dubravko
authors.initials: D
authors.lastname: Smud
authors.forename: Željko
authors.initials: Ž
authors.lastname: Jelinčić
authors.forename: Emil
authors.initials: E
authors.lastname: Kinda
authors.forename: Tihomir
authors.initials: T
authors.lastname: Kekez
authors.forename: Goran
authors.initials: G
authors.lastname: Augustin
authors.forename: Hrvoje
authors.initials: H
authors.lastname: Silovski
authors.forename: Petar
authors.initials: P
authors.lastname: Matošević
authors.forename: Tomislav
authors.initials: T
authors.lastname: Bruketa
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant; D003110:Colonic Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D017523:Croatia; D065426:Cytoreduction Surgical Procedures; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery; D009362:Neoplasm Metastasis
chemical_list: D000970:Antineoplastic Agents