title: Analysis on the Alpinia katsumadai components of Zingiberaceae plants and their functions on myeloma resistance.
abstract: Generally speaking, zingiberaceae plants with sweet fragrance are commonly seen as perennial herbs that contains numerous well-known crude drugs and fragrant plants like Amomum villosum, Amomumtsao-ko, Ginger, Alpinia katsumadai and Radix curcumae, which are widely used in daily life. This paper analyzed chemical components of Alpinia katsumadai of zingiberaceae and applied several laminar analysis to further develop its active ingredients, aiming to make sure its function on tumor assistance. Actually, cardamomin contained in Alpinia katsumadai has been recorded to act notably in myeloma resistance, which was verified by cholecystokinin-octopeptide (CCK-8) in this paper. Cardamom in is proved to have multiple anti-myeloma effects, including myeloma cell activity and proliferation control, cell cycle retardant and apoptosis induction, which indicates its value in the field of medical pharmacy.
authors.affiliation: Department of orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Jue
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Rubiao
authors.initials: R
authors.lastname: Qiu
authors.affiliation: Department of orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Lianjing
authors.initials: L
authors.lastname: Yuan
authors.affiliation: Department of orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Meng
authors.affiliation: Department of orthopedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Tang
mesh_terms: D032429:Alpinia / Q000737:chemistry; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D017209:Apoptosis / Q000187:drug effects; D059447:Cell Cycle Checkpoints / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D047188:Chalcones / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D019008:Drug Resistance, Neoplasm; D028523:Elettaria / Q000737:chemistry; D006801:Humans; D009101:Multiple Myeloma / Q000473:pathology*; D008517:Phytotherapy; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D047188:Chalcones; D010936:Plant Extracts; C436747:cardamonin