title: Emergence of a Novel Binary Toxin-Positive Strain of Clostridium difficile Associated With Severe Diarrhea That Was Not Ribotype 027 and 078 in China.
authors.affiliation: 1Xiangya Hospital of Central South University,Changsha,Hunan Province,China.
authors.forename: Chunhui
authors.initials: C
authors.lastname: Li
authors.affiliation: 1Xiangya Hospital of Central South University,Changsha,Hunan Province,China.
authors.forename: Sidi
authors.initials: S
authors.lastname: Liu
authors.affiliation: 1Xiangya Hospital of Central South University,Changsha,Hunan Province,China.
authors.forename: Pengcheng
authors.initials: P
authors.lastname: Zhou
authors.affiliation: 1Xiangya Hospital of Central South University,Changsha,Hunan Province,China.
authors.forename: Juping
authors.initials: J
authors.lastname: Duan
authors.affiliation: 1Xiangya Hospital of Central South University,Changsha,Hunan Province,China.
authors.forename: Qingya
authors.initials: Q
authors.lastname: Dou
authors.affiliation: 2Chinese Center for Disease Control and Prevention,Beijing,China.
authors.forename: Rui
authors.initials: R
authors.lastname: Zhang
authors.affiliation: 2Chinese Center for Disease Control and Prevention,Beijing,China.
authors.forename: Hong
authors.initials: H
authors.lastname: Chen
authors.affiliation: 2Chinese Center for Disease Control and Prevention,Beijing,China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Cheng
authors.affiliation: 1Xiangya Hospital of Central South University,Changsha,Hunan Province,China.
authors.forename: Anhua
authors.initials: A
authors.lastname: Wu
mesh_terms: D036002:ADP Ribose Transferases / Q000235:genetics*; D000368:Aged; D001426:Bacterial Proteins / Q000235:genetics*; D001427:Bacterial Toxins / Q000235:genetics*; D001483:Base Sequence; D002681:China; D016360:Clostridioides difficile / Q000235:genetics*; D004269:DNA, Bacterial / Q000032:analysis*; D003967:Diarrhea / Q000382:microbiology; D004761:Enterocolitis, Pseudomembranous / Q000150:complications / Q000382:microbiology*; D004768:Enterotoxins / Q000235:genetics*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D058885:Multilocus Sequence Typing; D009154:Mutation; D012097:Repressor Proteins / Q000235:genetics*; D021521:Ribotyping; D012720:Severity of Illness Index
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; D004269:DNA, Bacterial; D004768:Enterotoxins; D012097:Repressor Proteins; C105615:TcdC protein, Clostridium difficile; C041348:tcdA protein, Clostridium difficile; C031815:toxB protein, Clostridium difficile; D036002:ADP Ribose Transferases; C410164:actin-specific ADP-ribosyltransferase, Clostridium