title: Fosfomycin for Treatment of Prostatitis: New Tricks for Old Dogs.
abstract: Treatment options for prostatitis caused by multidrug-resistant gram-negative bacilli are limited. We report two cases cured with oral fosfomycin and provide a pharmacokinetic analysis of fosfomycin predose concentrations during treatment.
authors.affiliation: Department of Infectious Diseases, Austin Health Department of Medicine, University of Melbourne.
authors.forename: M Lindsay
authors.initials: ML
authors.lastname: Grayson
authors.affiliation: Department of Infectious Diseases, Austin Health.
authors.forename: Nenad
authors.initials: N
authors.lastname: Macesic
authors.affiliation: Department of Infectious Diseases, Austin Health Department of Infectious Diseases, Alfred Health.
authors.forename: Janine
authors.initials: J
authors.lastname: Trevillyan
authors.affiliation: Department of Medicine, University of Melbourne Department of Clinical Pharmacology, Austin Health, Melbourne, Australia.
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Ellis
authors.affiliation: Department of Medicine, University of Melbourne.
authors.forename: Phillip T
authors.initials: PT
authors.lastname: Zeglinski
authors.affiliation: Department of Infectious Diseases, Austin Health.
authors.forename: Nicholas H
authors.initials: NH
authors.lastname: Hewitt
authors.affiliation: Department of Infectious Diseases, Austin Health.
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Gardiner
authors.affiliation: Department of Medicine, University of Melbourne Department of Clinical Pharmacology, Austin Health, Melbourne, Australia.
authors.forename: Albert G
authors.initials: AG
authors.lastname: Frauman
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use*; D024901:Drug Resistance, Multiple, Bacterial; D005578:Fosfomycin / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011472:Prostatitis / Q000188:drug therapy*; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D000900:Anti-Bacterial Agents; D005578:Fosfomycin
keywords: fosfomycin; microbial drug resistance; pharmacology; prostatitis