title: Privilege Ynone Synthesis via Palladium-Catalyzed Alkynylation of "Super-Active Esters".
abstract: A neat palladium-catalyzed alkynylation reaction was developed with "super-active ester" as the carbonyl electrophile, which provides a clean and efficient synthetic protocol for a broad array of ynone compounds under CO-, Cu-, ligand-, and base-free conditions. The superior activity of triazine ester was rationalized by the strong electron-withdrawing ability and the unique affinity of triazine on palladium. A mechanistic experiment clearly demonstrated that the N-Pd coordination of triazine plays a crucial role for the highly efficient C-O activation.
authors.forename: Bo
authors.initials: B
authors.lastname: Yu
authors.forename: Huaming
authors.initials: H
authors.lastname: Sun
authors.forename: Zunyuan
authors.initials: Z
authors.lastname: Xie
authors.forename: Guofang
authors.initials: G
authors.lastname: Zhang
authors.forename: Li-Wen
authors.initials: LW
authors.lastname: Xu
authors.forename: Weiqiang
authors.initials: W
authors.lastname: Zhang
authors.forename: Ziwei
authors.initials: Z
authors.lastname: Gao