title: Microwave-assisted synthesis of chromenes: biological and chemical importance.
abstract: Chromenes constitute chemically important class of heterocyclic compounds having diverse biological and chemical importance. Development of environmentally benign, efficient and economical methods for the synthesis of chromenes remains a significant challenge in synthetic chemistry. The synthesis of chromenes, therefore, has attracted enormous attention from medicinal and organic chemists. Researchers have embraced the concepts of microwave (high speed) synthesis to produce biologically and chemically important chromenes in a time sensitive manner. This review will summarize the recent biological applications such as anticancer, antimicrobial, neurodegenerative and insecticidal activity of new chromenes prepared via microwave irradiation. The development of new methodologies for the synthesis of chromenes including green chemistry processes has also been discussed.
authors.affiliation: Pharmaceutical Sciences Department, College of Pharmacy, Rosalind Franklin University of Medicine & Science, 3333 Green Bay Road, North Chicago, IL 60064, USA.
authors.forename: Shivaputra A
authors.initials: SA
authors.lastname: Patil
authors.affiliation: Centre for Nano & Material Sciences, Jain University, Jain Global Campus, Bangalore 562112, Karnataka, India.
authors.forename: Siddappa A
authors.initials: SA
authors.lastname: Patil
authors.affiliation: Pharmaceutical Sciences Department, College of Pharmacy, Rosalind Franklin University of Medicine & Science, 3333 Green Bay Road, North Chicago, IL 60064, USA.
authors.forename: Renukadevi
authors.initials: R
authors.lastname: Patil
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry; D001578:Benzopyrans / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D007306:Insecticides / Q000138:chemical synthesis* / Q000737:chemistry; D008872:Microwaves
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D001578:Benzopyrans; D007306:Insecticides