title: Evaluation of the LINX antireflux procedure.
abstract: OBJECTIVE
  To evaluate the current data on the safety, efficacy, and indications for magnetic sphincter augmentation (MSA) using the LINX device to treat gastroesophageal reflux disease (GERD).
  
  
  RESULTS
  The LINX device has demonstrated excellent safety and GERD efficacy in several recent nonblinded, single arm studies with strict inclusion criteria and up to 3 years follow-up. Dysphagia has been the most common adverse effect occurring after LINX. Other gastrointestinal side-effects seen after laparoscopic fundoplication (bloating, gas, and inability to belch) may be less common after LINX.
  
  
  CONCLUSIONS
  The LINX device is a safe, well tolerated, and effective therapy for GERD in the short term. MSA should be considered for selected GERD patients without significant anatomic or motility defects. However, the long-term safety and efficacy of LINX - both alone and in comparison to current GERD therapies - remains to be determined.
authors.affiliation: aDepartment of Surgery, Brigham and Women's Hospital bHarvard Medical School cDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
authors.forename: Eric G
authors.initials: EG
authors.lastname: Sheu
authors.forename: David W
authors.initials: DW
authors.lastname: Rattner
mesh_terms: D057186:Comparative Effectiveness Research; D018662:Fundoplication / Q000379:methods; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans; D059346:Magnets / Q000009:adverse effects; D019990:Perioperative Care / Q000379:methods; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000009:adverse effects / Q000379:methods