title: Vesicles Formation by Zwitterionic Micelle and Poly-L-lysine: Solvation and Rotational Relaxation Study.
abstract: The stable unilamellar vesicles formation, having large potential applications in biological as well as biomedical fields, has been investigated in aqueous solution composed of a zwitterionic surfactant, N-hexadecyl-N,N-dimethylammonio-1-propanesulfonate (SB-16), and water-soluble cationic poly(amino acid), poly-L-lysine (PLL). Dynamic light scattering (DLS), transmission electron microscopy (TEM), and other optical spectroscopic techniques revealed the transformation of SB-16 micelles in aqueous solutions into stable unilamellar vesicles above a certain concentration (0.008 to 0.1% w/v) of PLL. Solvation and rotational dynamics of coumarin 480 (C-480) give the information on hydration behavior around the headgroup regions of SB-16 micelle and SB-16/PLL vesicle. It was observed that the hydration nature around the headgroup regions of SB-16/PLL vesicular system is higher than the head group regions of micellar system. Thus, PLL permits more water molecules in the headgroup regions of vesicular system.
authors.affiliation: Department of Chemistry, Indian Institute of Technology, Kharagpur 721302, West Bengal, India.
authors.forename: Jagannath
authors.initials: J
authors.lastname: Kuchlyan
authors.affiliation: Department of Chemistry, Indian Institute of Technology, Kharagpur 721302, West Bengal, India.
authors.forename: Debasis
authors.initials: D
authors.lastname: Banik
authors.affiliation: Department of Chemistry, Indian Institute of Technology, Kharagpur 721302, West Bengal, India.
authors.forename: Arpita
authors.initials: A
authors.lastname: Roy
authors.affiliation: Department of Chemistry, Indian Institute of Technology, Kharagpur 721302, West Bengal, India.
authors.forename: Niloy
authors.initials: N
authors.lastname: Kundu
authors.affiliation: Department of Chemistry, Indian Institute of Technology, Kharagpur 721302, West Bengal, India.
authors.forename: Nilmoni
authors.initials: N
authors.lastname: Sarkar
mesh_terms: D003374:Coumarins / Q000737:chemistry; D020285:Cryoelectron Microscopy / Q000379:methods; D000067493:Dynamic Light Scattering; D004553:Electric Conductivity; D008823:Micelles; D046529:Microscopy, Electron, Transmission; D009391:Nephelometry and Turbidimetry / Q000379:methods; D011107:Polylysine / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D011807:Quinolizines / Q000737:chemistry; D013501:Surface-Active Agents / Q000737:chemistry; D053835:Unilamellar Liposomes / Q000737:chemistry
chemical_list: D003374:Coumarins; D008823:Micelles; C094641:N-hexadecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate; D000644:Quaternary Ammonium Compounds; D011807:Quinolizines; D013501:Surface-Active Agents; D053835:Unilamellar Liposomes; C573700:coumarin 480; D011107:Polylysine