title: [Treatment of vulvar intra-epithelial neoplasias with Imiquimod].
abstract: The incidence of vulvar intra-epithelial neoplasia (VIN) is increasing in the developed countries especially in young women. There is little consensus regarding the optimal management. Surgery used to be the gold standard. Alternatives to surgery are now needed for the treatment of VIN. Many studies investigated the effectiveness of Imiquimod 5% cream in this pathology. We present a literature review of the results published on the subject.
authors.affiliation: Service de gynécologie-obstétrique et médecine fœtale, université François-Rabelais, CHRU de Tours, 2, boulevard Tonnellé, 37044 Tours cedex 9, France. Electronic address: julie.paternotte@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Paternotte
authors.affiliation: Service de gynécologie-obstétrique et médecine fœtale, université François-Rabelais, CHRU de Tours, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
authors.forename: T
authors.initials: T
authors.lastname: Hebert
authors.affiliation: Service de gynécologie-obstétrique et médecine fœtale, UMR Inserm U 1069, université François-Rabelais, CHRU de Tours, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
authors.forename: L
authors.initials: L
authors.lastname: Ouldamer
authors.affiliation: Service de gynécologie-obstétrique et médecine fœtale, UMR Inserm U 930, université François-Rabelais, CHRU de Tours, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
authors.forename: H
authors.initials: H
authors.lastname: Marret
authors.affiliation: Service de gynécologie-obstétrique et médecine fœtale, université François-Rabelais, CHRU de Tours, 2, boulevard Tonnellé, 37044 Tours cedex 9, France.
authors.forename: G
authors.initials: G
authors.lastname: Body
mesh_terms: D000634:Aminoquinolines / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002278:Carcinoma in Situ / Q000188:drug therapy* / Q000628:therapy; D005260:Female; D006801:Humans; D000077271:Imiquimod; D016896:Treatment Outcome; D014846:Vulvar Neoplasms / Q000188:drug therapy* / Q000628:therapy
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod
keywords: HPV; Imiquimod; Néoplasie vulvaire intra-épithéliale; Traitement; Treatment; Vulvar intraepithelial neoplasia