title: Exploration of the Visual System: Part 2: In Vivo Analysis Methods: Virtual-Reality Optomotor System, Fundus Examination, and Fluorescent Angiography.
abstract: The mouse has emerged as an animal model for many diseases. At IRO, we have used this animal to understand the development of many eye diseases and treatment of some of them. Precise evaluation of vision is a prerequisite for both these approaches. In this unit we describe three ways to measure vision: testing the optokinetic response, and evaluating the fundus by direct observation and by fluorescent angiography. Curr. Protoc. Mouse Biol. 2:207-218 © 2012 by John Wiley & Sons, Inc.
authors.affiliation: IRO (Institute for Research in Ophthalmology), Sion, Switzerland.|EPFL (Ecole Polytechnique Fédérale), Lausanne, Switzerland.
authors.forename: Fabienne
authors.initials: F
authors.lastname: Marcelli
authors.affiliation: IRO (Institute for Research in Ophthalmology), Sion, Switzerland.|Department of Ophthalmology, University of Lausanne, Lausanne, Switzerland.
authors.forename: Pascal
authors.initials: P
authors.lastname: Escher
authors.affiliation: IRO (Institute for Research in Ophthalmology), Sion, Switzerland.|Department of Ophthalmology, University of Lausanne, Lausanne, Switzerland.|EPFL (Ecole Polytechnique Fédérale), Lausanne, Switzerland.
authors.forename: Daniel F
authors.initials: DF
authors.lastname: Schorderet
keywords: contrast sensitivity; fluorescent angiography; fundus; ophthalmology; optokinetic response; spatial frequency