title: Glutathione.
abstract: Glutathione is an endogenous peptide with antioxidant and other metabolic functions. The nomenclature, formulae, elemental composition, and appearance and uses of the drug are included. The methods used for the synthesis and biosynthesis of glutathione are described. This profile contains the physical characteristics of the drug including: solubility, X-ray powder diffraction pattern, crystal structure, melting point, and differential scanning calorimetry. The spectral methods that were used for both the identification and analysis of glutathione include ultraviolet spectrum, vibrational spectrum, 1H and 13C nuclear magnetic resonance spectra, and mass spectrum. The profile also includes the compendial methods of analysis and the other methods of analysis that are reported in the literature. These other methods of e-analysis are: potentiometric, voltammetric, amperometric, spectrophotometric, specrtofluorometric, chemiluminescence, chromatographic and immunoassay methods. The stability of and several reviews on drug are also provided. More than 170 references are listed at the end this comprehensive profile on glutathione.
authors.affiliation: Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Amer M
authors.initials: AM
authors.lastname: Alanazi
authors.affiliation: Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Gamal A E
authors.initials: GA
authors.lastname: Mostafa
authors.affiliation: Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Electronic address: abadr@ksu.edu.sa.
authors.forename: Abdullah A
authors.initials: AA
authors.lastname: Al-Badr
mesh_terms: D000975:Antioxidants / Q000737:chemistry*; D002626:Chemistry, Pharmaceutical; D004355:Drug Stability; D005978:Glutathione / Q000737:chemistry*; D015394:Molecular Structure; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D000975:Antioxidants; D005978:Glutathione
keywords: Biosynthesis; Description; Glutathione; Methods of analysis; Physical characteristics; Reviews; Spectral properties; Stability; Synthesis; Uses