title: Hepatocyte-specific Hmgb1 Deletion.
abstract: High mobility group box 1 (HMGB1) plays a key role in human health and disease. Currently, three different labs in the USA use Cre-lox technology to create mice with a hepatocyte-specific Hmgb1 deletion (HMGB1-HC-KO mice) by backcrossing Hmgb1 (flox)/(flox) mice to Alb-Cre mice. This mouse strain has a different phenotype following exposure to several stressors.
authors.affiliation: a The Third Affiliated Hospital of Guangzhou Medical University ; Guangzhou , Guangdong , China.
authors.forename: Xiaofang
authors.initials: X
authors.lastname: Sun
authors.forename: Daolin
authors.initials: D
authors.lastname: Tang
mesh_terms: D000818:Animals; D001343:Autophagy; D024243:HMGB1 Protein / Q000378:metabolism*; D006801:Humans
chemical_list: D024243:HMGB1 Protein
keywords: HMGB1, knockout, liver, mice