title: kpath: integration of metabolic pathway linked data.
abstract: In the last few years, the Life Sciences domain has experienced a rapid growth in the amount of available biological databases. The heterogeneity of these databases makes data integration a challenging issue. Some integration challenges are locating resources, relationships, data formats, synonyms or ambiguity. The Linked Data approach partially solves the heterogeneity problems by introducing a uniform data representation model. Linked Data refers to a set of best practices for publishing and connecting structured data on the Web. This article introduces kpath, a database that integrates information related to metabolic pathways. kpath also provides a navigational interface that enables not only the browsing, but also the deep use of the integrated data to build metabolic networks based on existing disperse knowledge. This user interface has been used to showcase relationships that can be inferred from the information available in several public databases.
authors.affiliation: Departamento de Lenguajes y Ciencias de la Computación, Universidad de Málaga, Andalucía Tech, Ada Byron Research Building, E-29071 Málaga, Spain, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, Andalucía Tech, and IBIMA (Biomedical Research Institute of Málaga), E-29071 Málaga, Spain and CIBER de Enfermedades Raras (CIBERER) E-29071 Málaga, Spain ismael@lcc.uma.es.
authors.forename: Ismael
authors.initials: I
authors.lastname: Navas-Delgado
authors.affiliation: Departamento de Lenguajes y Ciencias de la Computación, Universidad de Málaga, Andalucía Tech, Ada Byron Research Building, E-29071 Málaga, Spain, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, Andalucía Tech, and IBIMA (Biomedical Research Institute of Málaga), E-29071 Málaga, Spain and CIBER de Enfermedades Raras (CIBERER) E-29071 Málaga, Spain.
authors.forename: María Jesús
authors.initials: MJ
authors.lastname: García-Godoy
authors.affiliation: Departamento de Lenguajes y Ciencias de la Computación, Universidad de Málaga, Andalucía Tech, Ada Byron Research Building, E-29071 Málaga, Spain, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, Andalucía Tech, and IBIMA (Biomedical Research Institute of Málaga), E-29071 Málaga, Spain and CIBER de Enfermedades Raras (CIBERER) E-29071 Málaga, Spain.
authors.forename: Esteban
authors.initials: E
authors.lastname: López-Camacho
authors.affiliation: Departamento de Lenguajes y Ciencias de la Computación, Universidad de Málaga, Andalucía Tech, Ada Byron Research Building, E-29071 Málaga, Spain, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, Andalucía Tech, and IBIMA (Biomedical Research Institute of Málaga), E-29071 Málaga, Spain and CIBER de Enfermedades Raras (CIBERER) E-29071 Málaga, Spain.
authors.forename: Maciej
authors.initials: M
authors.lastname: Rybinski
authors.affiliation: Departamento de Lenguajes y Ciencias de la Computación, Universidad de Málaga, Andalucía Tech, Ada Byron Research Building, E-29071 Málaga, Spain, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, Andalucía Tech, and IBIMA (Biomedical Research Institute of Málaga), E-29071 Málaga, Spain and CIBER de Enfermedades Raras (CIBERER) E-29071 Málaga, Spain Departamento de Lenguajes y Ciencias de la Computación, Universidad de Málaga, Andalucía Tech, Ada Byron Research Building, E-29071 Málaga, Spain, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, Andalucía Tech, and IBIMA (Biomedical Research Institute of Málaga), E-29071 Málaga, Spain and CIBER de Enfermedades Raras (CIBERER) E-29071 Málaga, Spain.
authors.forename: Armando
authors.initials: A
authors.lastname: Reyes-Palomares
authors.affiliation: Departamento de Lenguajes y Ciencias de la Computación, Universidad de Málaga, Andalucía Tech, Ada Byron Research Building, E-29071 Málaga, Spain, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, Andalucía Tech, and IBIMA (Biomedical Research Institute of Málaga), E-29071 Málaga, Spain and CIBER de Enfermedades Raras (CIBERER) E-29071 Málaga, Spain Departamento de Lenguajes y Ciencias de la Computación, Universidad de Málaga, Andalucía Tech, Ada Byron Research Building, E-29071 Málaga, Spain, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, Andalucía Tech, and IBIMA (Biomedical Research Institute of Málaga), E-29071 Málaga, Spain and CIBER de Enfermedades Raras (CIBERER) E-29071 Málaga, Spain.
authors.forename: Miguel Ángel
authors.initials: MÁ
authors.lastname: Medina
authors.affiliation: Departamento de Lenguajes y Ciencias de la Computación, Universidad de Málaga, Andalucía Tech, Ada Byron Research Building, E-29071 Málaga, Spain, Departamento de Biología Molecular y Bioquímica, Facultad de Ciencias, Universidad de Málaga, Andalucía Tech, and IBIMA (Biomedical Research Institute of Málaga), E-29071 Málaga, Spain and CIBER de Enfermedades Raras (CIBERER) E-29071 Málaga, Spain.
authors.forename: José F
authors.initials: JF
authors.lastname: Aldana-Montes
mesh_terms: D055442:Metabolome; D014584:User-Computer Interface