title: Reliability and Validity of Proposed DSM-5 ADHD Symptoms in a Clinical Sample of Adults.
abstract: The DSM-5 ADHD and Disruptive Behaviors Work Group proposed two major changes for diagnosis of attention deficit hyperactivity disorder (ADHD) in adults: (1) inclusion of four new impulsivity symptoms and (2) reduction in the number of symptoms required for assigning an ADHD diagnosis. In this case-control study, the performance of these modifications was assessed in a clinical sample of 133 adult subjects (68 ADHD cases and 65 non-ADHD control subjects). The proposed new impulsivity symptoms for adults do not improve ADHD diagnosis enough to overcome potential negative effects of changing the criteria. However, fewer symptoms than the six-of-nine threshold required by DSM-IV provided the best cutoff point for identifying adults who are impaired.
authors.affiliation: From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN).
authors.forename: Breno
authors.initials: B
authors.lastname: Matte
authors.affiliation: From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN).
authors.forename: Luis Augusto
authors.initials: LA
authors.lastname: Rohde
authors.affiliation: From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN).
authors.forename: J Blake
authors.initials: JB
authors.lastname: Turner
authors.affiliation: From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN).
authors.forename: Prudence W
authors.initials: PW
authors.lastname: Fisher
authors.affiliation: From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN).
authors.forename: Sa
authors.initials: S
authors.lastname: Shen
authors.affiliation: From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN).
authors.forename: Claiton H D
authors.initials: CH
authors.lastname: Bau
authors.affiliation: From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN).
authors.forename: Joel T
authors.initials: JT
authors.lastname: Nigg
authors.affiliation: From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN).
authors.forename: Eugenio H
authors.initials: EH
authors.lastname: Grevet
mesh_terms: D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis* / Q000503:physiopathology; D016009:Chi-Square Distribution; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012372:ROC Curve; D015203:Reproducibility of Results; D055815:Young Adult