title: Emergence of human babesiosis along the border of China with Myanmar: detection by PCR and confirmation by sequencing.
abstract: Babesiosis is a tick-borne, zoonotic disease caused by Babesia spp. Two cases of babesiosis were detected by nested polymerase chain reaction (PCR) in Yunnan province, China, and further confirmed by molecular assay. The blood smears showed intraerythrocytic ring form and tetrads typical of small B. microti. In both cases, the rapid diagnostic test (RDT) ruled out the possibility of co-infections with malaria. Neither case was initially diagnosed because of the low Babesia parasitemia. These two cases of babesiosis in areas along the Myanmar-China border pose the question of the emergence of this under recognized infection in countries or areas where malaria is endemic.
authors.affiliation: Department of Parasitology, Medical College of Soochow University , Suzhou 215123, Jiangsu province, China ; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention , Shanghai 200025, China ; Key Laboratory of Parasite & Vector Biology, Ministry of Health, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis , Shanghai 200025, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Tengchong Center for Disease Control and Prevention , Tengchong 679100, Yunnan province, China.
authors.forename: Sheng-Guo
authors.initials: SG
authors.lastname: Li
authors.affiliation: Tengchong Center for Disease Control and Prevention , Tengchong 679100, Yunnan province, China.
authors.forename: Jia-Zhi
authors.initials: JZ
authors.lastname: Wang
authors.affiliation: Department of Parasitology, Medical College of Soochow University , Suzhou 215123, Jiangsu province, China ; National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention , Shanghai 200025, China ; Key Laboratory of Parasite & Vector Biology, Ministry of Health, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis , Shanghai 200025, China.
authors.forename: Ji-Lei
authors.initials: JL
authors.lastname: Huang
authors.affiliation: National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention , Shanghai 200025, China ; Key Laboratory of Parasite & Vector Biology, Ministry of Health, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis , Shanghai 200025, China.
authors.forename: He-Jun
authors.initials: HJ
authors.lastname: Zhou
authors.affiliation: National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention , Shanghai 200025, China ; Key Laboratory of Parasite & Vector Biology, Ministry of Health, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis , Shanghai 200025, China.
authors.forename: Jun-Hu
authors.initials: JH
authors.lastname: Chen
authors.affiliation: National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention , Shanghai 200025, China ; Key Laboratory of Parasite & Vector Biology, Ministry of Health, WHO Collaborating Centre for Malaria, Schistosomiasis and Filariasis , Shanghai 200025, China.
authors.forename: Xiao-Nong
authors.initials: XN
authors.lastname: Zhou
keywords: Myanmar–China border areas; babesiosis; malaria; molecular assay