title: Asymmetric Epoxidation Using Hydrogen Peroxide as Oxidant.
abstract: Asymmetric epoxidation is one of the most important transformations in organic synthesis. Although tremendous progress was achieved in this field in the 1980s and 1990s, it is still desirable from both economical and ecological views to develop environmentally friendly catalytic epoxidation with a broad substrate scope. Hydrogen peroxide is a safe and cheap oxidant, which is easy to handle and generates water as the sole byproduct. Therefore, asymmetric epoxidation of olefins using hydrogen peroxide as oxidant has been a very active research field and has been investigated by many research groups in recent years. In this review, the exciting very recent developments of this rapidly growing area are surveyed and organized according to the catalyst systems.
authors.affiliation: Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, IL 60637, USA.
authors.forename: Chuan
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, IL 60637, USA. yamamoto@uchicago.edu, hyamamoto@jsc.chubu.ac.jp.|Molecular Catalyst Research Center, Chubu University, 1200 Matsumoto, Kasugai, Aichi 487-8501, Japan. yamamoto@uchicago.edu, hyamamoto@jsc.chubu.ac.jp.
authors.forename: Hisashi
authors.initials: H
authors.lastname: Yamamoto
mesh_terms: D002384:Catalysis; D003516:Cycloparaffins / Q000737:chemistry; D004852:Epoxy Compounds / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D003516:Cycloparaffins; D004852:Epoxy Compounds; D047028:Macrocyclic Compounds; D006861:Hydrogen Peroxide
keywords: asymmetric synthesis; catalysis; epoxidation; hydrogen peroxide; olefins