title: Macular Telangiectasia Type 2 Without Clinically Detectable Vasculopathy.
abstract: OBJECTIVE
  Macular telangiectasia type 2 is a bilateral disease with characteristic alterations of the macular capillary network and neural atrophy. Vascular and neurodegenerative hypotheses have been proposed to explain these clinical findings, but many questions regarding the pathogenesis remain.
  
  
  METHODS
  We report the case of a 69-year-old woman with macular telangiectasia type 2 in whom multimodal fundus imaging identified neuronal features without clinically detectable vasculopathy.
  
  
  CONCLUSIONS
  We hypothesize that parallel neuronal and vascular pathogenic pathways secondary to Müller cell dysfunction, the cause of which remains obscure, explain the clinical features of this case of macular telangiectasia type 2.
authors.affiliation: Macular Research Group, Save Sight Institute, University of Sydney, Sydney, Australia.
authors.forename: Mark C
authors.initials: MC
authors.lastname: Gillies
authors.affiliation: Macular Research Group, Save Sight Institute, University of Sydney, Sydney, Australia2Medical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, England.
authors.forename: Hemal
authors.initials: H
authors.lastname: Mehta
authors.affiliation: Medical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, England.
authors.forename: Alan C
authors.initials: AC
authors.lastname: Bird
mesh_terms: D000368:Aged; D001284:Atrophy; D002199:Capillary Permeability; D063928:Ependymoglial Cells / Q000473:pathology*; D005260:Female; D019793:Fluorescein / Q000378:metabolism; D005451:Fluorescein Angiography; D006801:Humans; D064847:Multimodal Imaging; D012164:Retinal Diseases / Q000175:diagnosis*; D058456:Retinal Telangiectasis / Q000175:diagnosis*; D012171:Retinal Vessels / Q000378:metabolism / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity
chemical_list: D019793:Fluorescein