title: Reference values of T lymphocyte subsets among health adults in Inner Mongolia Region.
abstract: Estimation of T-lymphocyte subsets continues to be an important aspect for monitoring HIV disease progression and response to antiretroviral therapy. Most of the diagnostic laboratories often rely on studies from western for CD4+T-lymphocyte reference values, which could, often be unreliable for usage in local settings. To establish the normal reference values of T lymphocyte subsets from healthy people of Inner Mongolia Autonomous Region, flow cytometry was performed to determine the reference ranges for lymphocyte subsets (CD3 and CD4 cells) in 400 healthy multiracial adult population from 12 League Cities in Inner Mongolia Region, China. The basic information including age, gender, nationality and history was collected. There were significant differences in the absolute counting, percentage of CD3+T lymphocytes, and CD4+T lymphocyte percentage counting among different age groups. There were significant differences in CD3+, CD4+T lymphocyte percentage in the groups with different genders. There were significant differences in CD3+T lymphocyte percentage count, absolute count of CD4+T lymphocytes and CD4+T lymphocyte percentage counting in the group with ages of 16-20. There were dramatic differences in CD3+T lymphocyte percentage count and CD4+T lymphocyte percentage counting in the group with ages of 31-40. There were significant differences in CD4+T lymphocyte percentage counting. By this study, age, gender and ethnic specific lymphocyte subset reference ranges have been locally established in Inner Mongolia Autonomous Region.
authors.affiliation: Department of AIDS/STD Control and Prevention, Inner Mongolia Center for Disease Control and Prevention Hohhot 010031, Inner Mongolia, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Yang
authors.affiliation: Department of AIDS/STD Control and Prevention, Inner Mongolia Center for Disease Control and Prevention Hohhot 010031, Inner Mongolia, China.
authors.forename: Yumei
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of AIDS/STD Control and Prevention, Inner Mongolia Center for Disease Control and Prevention Hohhot 010031, Inner Mongolia, China.
authors.forename: Haoxue
authors.initials: H
authors.lastname: Li
authors.affiliation: Department of AIDS/STD Control and Prevention, Inner Mongolia Center for Disease Control and Prevention Hohhot 010031, Inner Mongolia, China.
authors.forename: Yongming
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Department of AIDS/STD Control and Prevention, Inner Mongolia Center for Disease Control and Prevention Hohhot 010031, Inner Mongolia, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Qu
authors.affiliation: Department of AIDS/STD Control and Prevention, Inner Mongolia Center for Disease Control and Prevention Hohhot 010031, Inner Mongolia, China.
authors.forename: Jingyuan
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of AIDS/STD Control and Prevention, Inner Mongolia Center for Disease Control and Prevention Hohhot 010031, Inner Mongolia, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Tao
keywords: Inner Mongolia; T lymphocyte subsets; normal reference value