title: Study of Ebola Virus Disease Survivors in Guinea.
abstract: BACKGROUND
  There is a paucity of data regarding health consequences of Ebola virus disease among survivors.
  
  
  METHODS
  We surveyed 105 Ebola virus disease survivors postdischarge from an Ebola treatment unit in Guinea using a standard data collection form. Patients rated recovery as the percentage of improvement in functional status, where 0% represents "unable to perform" and 100% represents "able to perform at prior level."
  
  
  RESULTS
  The mean ± standard deviation time interval between hospital discharge and administration of questionnaire was 103.5 ± 47.9 days in 105 survivors. Anorexia was reported by 103 patients, with varying severity levels: mild (n = 33), moderate (n = 65), or severe (n = 5). Reported pain according to site was chest (30.7%), joint (86.7%), muscle (26.7%), and back (45.7%), among others. Recovery in functional status was graded as mild (10%-30%) (n = 2 [1.9%]), moderate (40%-70%) (n = 52 [50.0%]), and excellent (80%-100%) (n = 50 [48.1%]). Severity of arthralgia (R(2) = 0.09; P = .008) was directly associated with lower recovery in functional status in multivariate analysis.
  
  
  CONCLUSIONS
  Ebola virus disease survivors frequently reported anorexia and arthralgia. Severity of arthralgia was related to lower functional recovery. There may be a role for focused screening and intervention for symptoms identified in this study of survivors.
authors.affiliation: Zeenat Qureshi Clinical Neuroscience Institute, Donka National Hospital, Conakry, Guinea Zeenat Qureshi Stroke Institute, St Cloud, Minnesota.
authors.forename: Adnan I
authors.initials: AI
authors.lastname: Qureshi
authors.affiliation: Rubin Institute of Advanced Orthopedics, Sinai Hospital, Baltimore, Maryland.
authors.forename: Morad
authors.initials: M
authors.lastname: Chughtai
authors.affiliation: Department of Neurosurgery, Donka National Hospital.
authors.forename: Tokpagnan Oscar
authors.initials: TO
authors.lastname: Loua
authors.affiliation: Department of Visceral Surgery, China-Guinea Friendship Hospital.
authors.forename: Jean
authors.initials: J
authors.lastname: Pe Kolie
authors.affiliation: Office of Directress and General Manager, Donka National Hospital, Conakry, Guinea.
authors.forename: Hadja Fatou Sikhe
authors.initials: HF
authors.lastname: Camara
authors.affiliation: Rubin Institute of Advanced Orthopedics, Sinai Hospital, Baltimore, Maryland.
authors.forename: Muhammad Fawad
authors.initials: MF
authors.lastname: Ishfaq
authors.affiliation: Department of Infectious Diseases, University of Cheikh Anta Diop of Dakar, Sengal.
authors.forename: Cheikh Tidane
authors.initials: CT
authors.lastname: N'Dour
authors.affiliation: Department of Neurosurgery, Donka National Hospital National Program to Combat Trauma and Violence in Guinea, Ministry of Health and World Health Organization, Conakry.
authors.forename: Kezely
authors.initials: K
authors.lastname: Beavogui
mesh_terms: D000293:Adolescent; D000328:Adult; D018771:Arthralgia; D029043:Ebolavirus; D005260:Female; D016701:Guinea / Q000453:epidemiology; D006282:Health Personnel; D019142:Hemorrhagic Fever, Ebola / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017741:Survivors / Q000706:statistics & numerical data*; D055815:Young Adult
keywords: Ebola virus; Ebola virus disease; Guinea; arthralgia; survivors