title: Efficacy and Safety of Endovenous Laser Ablation in Very Large and Tortuous Great Saphenous Veins.
abstract: OBJECTIVE
  To investigate the efficacy and safety of endovenous laser ablation (EVLA) with high energy delivery in large great saphenous veins (GSVs) at 1-year sonographic follow-up.
  
  
  METHODS
  Retrospective review of 385 patients who underwent EVLA between August 2011 and September 2013 was conducted, and 44 consecutive patients (21 women [47%]; mean age, 41 y; range, 23-66 y) with 49 large GSVs were included. Vein size and clinical follow-up results were recorded. A 600-μm bare-tipped 1,470-nm laser fiber was used for the EVLA procedure. Intended energy delivery was 150 J/cm (10 sessions at 15 W) for proximal GSV segments less than 20 mm in diameter and 195 J/cm (13 sessions at 15 W) for larger veins. Improvements in clinical and quality-of-life scores at 6 months were assessed with three validated scoring systems.
  
  
  RESULTS
  Mean GSV diameter was 16.95 mm (range, 15-26 mm). Five patients had GSVs at least 20 mm in diameter. Technical success was observed in 48 GSVs (97.9%) at 1-month follow-up. A second EVLA treatment was performed in one case and achieved closure, for a GSV occlusion rate of 100% at 6 months. All patients showed significant clinical improvement on all three scoring systems (P < .001). One-year follow-up was completed in 48 of 49 cases (98%). No recanalization was observed at 1-year follow-up, and there were no major complications.
  
  
  CONCLUSIONS
  Sonographic follow-up at 1 year shows that EVLA is an effective and safe procedure with excellent technical success rates in the treatment of large GSVs.
authors.affiliation: Department of Radiology, Maltepe University School of Medicine, Feyzullah Street, no. 39, Maltepe, Istanbul 34844, Istanbul, Turkey.. Electronic address: mmatasoy@gmail.com.
authors.forename: Mehmet Mahir
authors.initials: MM
authors.lastname: Atasoy
mesh_terms: D000328:Adult; D000368:Aged; D015984:Causality; D015897:Comorbidity; D057510:Endovascular Procedures / Q000379:methods / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D015994:Incidence; D053685:Laser Therapy / Q000379:methods / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology* / Q000517:prevention & control; D011788:Quality of Life; D012189:Retrospective Studies; D012307:Risk Factors; D012501:Saphenous Vein / Q000601:surgery*; D016896:Treatment Outcome; D014421:Turkey / Q000453:epidemiology; D014689:Venous Insufficiency / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery*; D055815:Young Adult