title: Comparison of intraocular pressure measurement with Scheimpflug-based noncontact tonometer with and without hydrogel contact lenses.
abstract: OBJECTIVE
  The objective was to determine the repeatability of intraocular pressure (IOP) measurements made through a soft contact lens (CL) using the Scheimpflug noncontact tonometry in healthy subjects.
  
  
  METHODS
  This prospective, randomized, single-center study included one eye of 88 subjects (40 male and 48 female). Only participants without glaucoma or any other ocular pathology were included in this study. Three consecutive IOP measurements by the Scheimpflug noncontact tonometry were performed with and without daily disposable hydrogel CLs (-0.50 DS) (Dailies-nelfilcon A, 69% water, 8.7 mm base curve, 14 mm diameter, center thickness 0.10 mm) by a single operator. To avoid any bias arising from diurnal variation, all measurements were made at a similar time of day (11 am ± 1 h). The repeatability of IOP measurements using the Scheimpflug noncontact tonometry with and without CLs was evaluated using Pearson's correlation analysis. Bland-Altman plotting was used to assess the limits of agreement between the measurements with and without CLs.
  
  
  RESULTS
  The mean (± standard deviation) IOPs with and without CL were 13.80 ± 2.70 and 13.79 ± 2.54 mm of Hg respectively. The mean difference was 0.01 ± 0.16 (95% confidence interval, +1.97 to - 2.00) mm Hg. Statistical analysis via paired t-test showed no statistical difference between the two groups with (P = 0.15). A good correlation was found for IOP measurements with and without CL (r = 0.93, P < 0.001). Good test-retest reliability was found when IOP was measured with and without CL.
  
  
  CONCLUSIONS
  There was no significant difference between IOP measured with and without CLs by Scheimpflug noncontact tonometry.
authors.affiliation: Narayana Nethralaya, Bengaluru, Karnataka, India.
authors.forename: Mukesh
authors.initials: M
authors.lastname: Kumar
authors.forename: Rohit
authors.initials: R
authors.lastname: Shetty
authors.forename: Chaitra
authors.initials: C
authors.lastname: Jayadev
authors.forename: Debarun
authors.initials: D
authors.lastname: Dutta
authors.forename: Maneck D
authors.initials: MD
authors.lastname: Nicolsan
authors.forename: Sriharsha
authors.initials: S
authors.lastname: Nagaraj
authors.forename: Rajesh S
authors.initials: RS
authors.lastname: Kumar
mesh_terms: D000328:Adult; D002940:Circadian Rhythm / Q000502:physiology; D003263:Contact Lenses, Hydrophilic; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D011446:Prospective Studies; D012030:Refractive Errors / Q000150:complications / Q000628:therapy*; D015203:Reproducibility of Results; D014065:Tonometry, Ocular / Q000379:methods*; D055815:Young Adult