title: Bioactive prenylated xanthones from the stems of Cratoxylum cochinchinense.
abstract: Cochinchinones M-U (1-9), together with 12 known compounds (10-21), were isolated from the stems of Cratoxylum cochinchinense (Lour.) Blume. Their structures were determined on the basis of extensive spectroscopic data analyses. In addition, their retinoid X receptor-α transcriptional activities were evaluated using an in vitro assay.
authors.affiliation: a Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632 , China.
authors.forename: Ying-Hui
authors.initials: YH
authors.lastname: Duan
authors.forename: Yi
authors.initials: Y
authors.lastname: Dai
authors.forename: Guang-Hui
authors.initials: GH
authors.lastname: Wang
authors.forename: Liu-Yuan
authors.initials: LY
authors.lastname: Chen
authors.forename: Hai-Feng
authors.initials: HF
authors.lastname: Chen
authors.forename: De-Quan
authors.initials: DQ
authors.lastname: Zeng
authors.forename: Yao-Lan
authors.initials: YL
authors.lastname: Li
authors.forename: Xin-Sheng
authors.initials: XS
authors.lastname: Yao
mesh_terms: D028084:Clusiaceae / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006801:Humans; D049409:Luciferases, Firefly / Q000378:metabolism; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry; D054876:Prenylation; D047490:Retinoid X Receptor alpha / Q000187:drug effects*; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
chemical_list: D004365:Drugs, Chinese Herbal; D047490:Retinoid X Receptor alpha; D044004:Xanthones; D049409:Luciferases, Firefly
keywords: Cratoxylum cochinchinense; Guttiferae; RXRα transcriptional activity; xanthone