title: [Allergies and adverse events associated with fluoroquinolones].
abstract: The prescription ot fluoroquinolones has been constantly increasing over the past decade. consequently, an increasing number of hyper-sensitivity reactions and adverse events have been reported. The aim of the review is to discuss the incidence of hypersensitivity reactions either IgE (immediate) or T cells mediated (delayed). We will make an overview ofthe diagnostic tools available to detect such hypersensitivity reactions. Finally, the specific adverse events associated with fluoroquinolones, including tendinopathy, chondrotoxicity, peripheral neuropathy or retinal detachment will be discussed.
authors.forename: Y
authors.initials: Y
authors.lastname: Muller
authors.forename: D
authors.initials: D
authors.lastname: Andrey
authors.forename: S
authors.initials: S
authors.lastname: Emonet
authors.forename: T
authors.initials: T
authors.lastname: Harr
authors.forename: D
authors.initials: D
authors.lastname: Spoerl
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000276:immunology; D004342:Drug Hypersensitivity / Q000209:etiology*; D024841:Fluoroquinolones / Q000009:adverse effects* / Q000276:immunology; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000209:etiology / Q000276:immunology; D007073:Immunoglobulin E / Q000276:immunology; D015994:Incidence; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D007073:Immunoglobulin E