title: Study of the effect of 'Ataulfo' mango (Mangifera indica L.) intake on mammary carcinogenesis and antioxidant capacity in plasma of N-methyl-N-nitrosourea (MNU)-treated rats.
abstract: The effect of 'Ataulfo' mango consumption on chemically induced mammary carcinogenesis and plasma antioxidant capacity in rats treated with N-methyl-N-nitrosourea (MNU) was studied. Mango was administered in the drinking water (0.02-0.06g/mL) during both short-term and long-term (LT) periods to rats treated or not with MNU. Rats treated with MNU showed no differences in mammary carcinogenesis or in plasma antioxidant capacity measured by both ferric reducing/antioxidant power (FRAP) and total oxyradical scavenging capacity assays. However, in animals not treated with MNU but with a LT intake of mango the plasma antioxidant capacity as measured by the FRAP assay tended to increase in a dose-dependent manner. This suggests that mango consumption by healthy subjects may increase antioxidants in plasma.
authors.affiliation: Laboratorio de Fitoquímicos y Nutrición, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Avenida de las Ciencias, Juriquilla, Querétaro, 76230 Qro., Mexico.
authors.forename: Pablo
authors.initials: P
authors.lastname: García-Solís
authors.affiliation: Laboratorio de Fitoquímicos y Nutrición, Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Avenida de las Ciencias, Juriquilla, Querétaro, 76230 Qro., Mexico. Electronic address: yahia@uaq.mx.
authors.forename: Elhadi M
authors.initials: EM
authors.lastname: Yahia
authors.affiliation: Instituto de Neurobiología, Universidad Nacional Autónoma de México, Campus UAQ-UNAM, Juriquilla, Querétaro 76230, Mexico.
authors.forename: Carmen
authors.initials: C
authors.lastname: Aceves
keywords: Fruit; Mammary cancer; Mangifera indica; Phytochemicals; Rat