title: Long term clinical outcome of dental implants placed in a patient with Singleton-Merten syndrome.
abstract: METHODS
  Singleton-Merten syndrome is an extremely rare autosomal dominant condition with less than 10 reported cases in the literature. It is characterized by abnormal aortic calcifications and dental abnormalities. The goal of this case report is to discuss the abnormal oral clinical features and the modified treatment protocol that was used in order to achieve osseointegration of dental implants in a patient having abnormal bone density and bone turnover associated with Singleton-Merten Syndrome.
  
  
  CONCLUSIONS
  Following extraction of the remaining teeth, titanium implants (Friadent GmbH, Mannheim, Germany and Straumann(®), Basel, Switzerland) were placed in the upper and lower jaw of the patient. The upper jaw which was treated with dental implants, received a bar supported implant retained prosthesis and the lower jaw an implant retained telescopic prosthesis. The patient was regularly followed up for the past 13 years during which, clinical and radiological evaluation of osseointegration was undertaken. All the loaded implants showed clinical and radiographic evidence of osseointegration. With a follow up of 13 years after insertion of the first implant, the patient reported functioning well with no complications.
  
  
  CONCLUSIONS
  The treatment with dental implants in the extremely rare Singleton-Merten syndrome patients is a reasonable treatment option to rehabilitate maxillofacial aesthetics and establish normal function of the jaws.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Katharinen Hospital, Kriegsbergstr. 60, D-70174 Stuttgart, Germany. Electronic address: r.rodriguez@klinikum-stuttgart.de.
authors.forename: Reena
authors.initials: R
authors.lastname: Rodriguez
authors.affiliation: Department of Oral and Maxillofacial Surgery, Katharinen Hospital, Kriegsbergstr. 60, D-70174 Stuttgart, Germany. Electronic address: n.hartmann@klinikum-stuttgart.de.
authors.forename: Nico
authors.initials: N
authors.lastname: Hartmann
authors.affiliation: Department of Prosthetic Dentistry, University of Muenster, Germany. Electronic address: Ludger.Figgener@ukmuenster.de.
authors.forename: Ludger
authors.initials: L
authors.lastname: Figgener
authors.affiliation: Department of Cranio-Maxillofacial Surgery, University of Muenster, Germany. Electronic address: Johannes.Kleinheinz@ukmuenster.de.
authors.forename: Johannes
authors.initials: J
authors.lastname: Kleinheinz
authors.affiliation: Department of Oral and Maxillofacial Surgery, Katharinen Hospital, Kriegsbergstr. 60, D-70174 Stuttgart, Germany. Electronic address: d.weingart@klinikum-stuttgart.de.
authors.forename: Dieter
authors.initials: D
authors.lastname: Weingart
mesh_terms: D000293:Adolescent; D001018:Aortic Diseases / Q000378:metabolism / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery*; D015519:Bone Density; D016723:Bone Remodeling; D003744:Dental Enamel Hypoplasia / Q000378:metabolism / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery*; D003758:Dental Implantation, Endosseous / Q000379:methods*; D004955:Esthetics, Dental; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008663:Metacarpus / Q000002:abnormalities* / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery; D009135:Muscular Diseases / Q000378:metabolism / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery*; D018126:Odontodysplasia / Q000378:metabolism / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery*; D056948:Orthognathic Surgical Procedures; D016348:Osseointegration; D010024:Osteoporosis / Q000378:metabolism / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery*; D014025:Titanium; D061205:Vascular Calcification / Q000378:metabolism / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery*
chemical_list: D014025:Titanium
keywords: Abnormal bone quality; Osseointegration; Singleton–Merten syndrome