title: Quantifying the complexity of human colonic pressure signals using an entropy measure.
abstract: Studying the complexity of human colonic pressure signals is important in understanding this intricate, evolved, dynamic system. This article presents a method for quantifying the complexity of colonic pressure signals using an entropy measure. As a self-adaptive non-stationary signal analysis algorithm, empirical mode decomposition can decompose a complex pressure signal into a set of intrinsic mode functions (IMFs). Considering that IMF2, IMF3, and IMF4 represent crucial characteristics of colonic motility, a new signal was reconstructed with these three signals. Then, the time entropy (TE), power spectral entropy (PSE), and approximate entropy (AE) of the reconstructed signal were calculated. For subjects with constipation and healthy individuals, experimental results showed that the entropies of reconstructed signals between these two classes were distinguishable. Moreover, the TE, PSE, and AE can be extracted as features for further subject classification.
authors.forename: Fei
authors.initials: F
authors.lastname: Xu
authors.forename: Guozheng
authors.initials: G
authors.lastname: Yan
authors.forename: Kai
authors.initials: K
authors.lastname: Zhao
authors.forename: Li
authors.initials: L
authors.lastname: Lu
authors.forename: Zhiwu
authors.initials: Z
authors.lastname: Wang
authors.forename: Jinyang
authors.initials: J
authors.lastname: Gao
mesh_terms: D003106:Colon / Q000503:physiopathology*; D003248:Constipation / Q000175:diagnosis* / Q000503:physiopathology*; D003627:Data Interpretation, Statistical; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D006801:Humans; D008365:Manometry / Q000295:instrumentation / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods; D011312:Pressure; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014160:Transducers, Pressure; D059015:Wireless Technology