title: [A review of diseases related to the intake of gluten].
abstract: Cereals are considered a basic food. Through the development of cooking, the human being has produced high- gluten-content food, so that it could make the most of its nutritional properties. Wheat is becoming one of the key elements of the Mediterranean diet. Amongst gluten- intake-related pathologies- gluten is present mainly in wheat, barley and rye- celiac disease (CD) is the most well-known. CD is a chronic inflammatory condition which affects gastrointestinal tract which develops in genetically predisposed individuals. The most common manifestation of CD is nutrients malabsorption. This protein trigger other pathology, wheat allergy (WA), which is an adverse immunological effect to gluten due to E immunoglobulin. A recent increased in non celiac gluten sensitivity (NCGS) has also been noticed, defined as the emergence of a range of gluten-intake related symptoms in patients for which celiac disease and wheat allergy have been ruled out. This article discusses these three conditions with their phatogenic mecanisms and the different clinic manifestations.
authors.affiliation: Servicio de Aparato Digestivo del Complejo Asistencial Universitario de León.. luisvaqueroayala@gmail.com.
authors.forename: Luis
authors.initials: L
authors.lastname: Vaquero
authors.affiliation: Servicio de Aparato Digestivo del Complejo Asistencial Universitario de León.. luisvaqueroayala@gmail.com.
authors.forename: Begoña
authors.initials: B
authors.lastname: Alvarez-Cuenllas
authors.affiliation: Servicio de Aparato Digestivo del Complejo Asistencial Universitario de León.. luisvaqueroayala@gmail.com.
authors.forename: Laura
authors.initials: L
authors.lastname: Rodríguez-Martín
authors.affiliation: Servicio de Aparato Digestivo del Complejo Asistencial Universitario de León.. luisvaqueroayala@gmail.com.
authors.forename: Marta
authors.initials: M
authors.lastname: Aparicio
authors.affiliation: Servicio de Aparato Digestivo del Complejo Asistencial Universitario de León. Centro de Investigación Biomédica en Red de Enfermendades Hepáticas y Digestivas (CIBERehd) e IBIOMED, España.. luisvaqueroayala@gmail.com.
authors.forename: Francisco
authors.initials: F
authors.lastname: Jorquera
authors.affiliation: Servicio de Aparato Digestivo del Complejo Asistencial Universitario de León. Centro de Investigación Biomédica en Red de Enfermendades Hepáticas y Digestivas (CIBERehd) e IBIOMED, España.. luisvaqueroayala@gmail.com.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Olcoz
authors.affiliation: Servicio de Aparato Digestivo del Complejo Asistencial Universitario de León.. luisvaqueroayala@gmail.com.
authors.forename: Santiago
authors.initials: S
authors.lastname: Vivas
mesh_terms: D002446:Celiac Disease / Q000178:diet therapy / Q000209:etiology*; D055050:Diet, Gluten-Free; D005983:Glutens / Q000009:adverse effects*; D006801:Humans; D008286:Malabsorption Syndromes; D021182:Wheat Hypersensitivity / Q000503:physiopathology / Q000628:therapy
chemical_list: D005983:Glutens