title: Gear Up in Circles.
abstract: Two studies published in this issue of Molecular Cell (Rybak-Wolf et al., 2015) and in the April issue of Nature Neuroscience (You et al., 2015) independently report the upregulated expression of back-spliced circular RNAs (circRNAs) in brains and suggest that they have a potential to regulate synaptic function.
authors.affiliation: State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address: linglingchen@sibcb.ac.cn.
authors.forename: Ling-Ling
authors.initials: LL
authors.lastname: Chen
authors.affiliation: Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, CAS Center for Excellence in Brain Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address: liyang@picb.ac.cn.
authors.forename: Li
authors.initials: L
authors.lastname: Yang
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D003712:Dendrites / Q000378:metabolism*; D005260:Female; D008297:Male; D009473:Neuronal Plasticity / Q000502:physiology*; D019581:Neuropil / Q000378:metabolism*; D012313:RNA / Q000378:metabolism*; D013569:Synapses / Q000235:genetics*
chemical_list: D012313:RNA