title: An alternative to force.
abstract: Researchers have discovered a synthetic small molecule that activates a mechanosensitive ion channel involved in a blood disorder.
authors.affiliation: Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
authors.forename: Amanda
authors.initials: A
authors.lastname: Patel
authors.affiliation: Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Demolombe
authors.affiliation: Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
authors.forename: Eric
authors.initials: E
authors.lastname: Honoré
mesh_terms: D000818:Animals; D006801:Humans; D007473:Ion Channels / Q000819:agonists* / Q000378:metabolism*; D040542:Mechanotransduction, Cellular / Q000502:physiology*; D054852:Small Molecule Libraries / Q000494:pharmacology*
chemical_list: D007473:Ion Channels; D054852:Small Molecule Libraries
keywords: agonist; biophysics; cell volume regulation; ion channel; mechanotransduction; mouse; neuroscience; physiology; red blood cells; structural biology