title: Catalytic Intramolecular Aminofluorination, Oxyfluorination, and Carbofluorination with a Stable and Versatile Hypervalent Fluoroiodine Reagent.
abstract: Application of a fluoroiodine analogue of the Togni reagent was studied in fluorocyclization reactions. In the presence of a transition-metal catalyst the applied fluoroiodine reagent can be used for aminofluorination, oxyfluorination, and carbofluorination reactions. The described procedure has a very broad synthetic scope for preparation of functionalized hetero- and isocyclic compounds having a tertiary fluorine substituent.
authors.affiliation: Department of Organic Chemistry, Stockholm University (Sweden) http://www.organ.su.se/ks/
authors.forename: Weiming
authors.initials: W
authors.lastname: Yuan
authors.affiliation: Department of Organic Chemistry, Stockholm University (Sweden) http://www.organ.su.se/ks/. kalman@organ.su.se.
authors.forename: Kálmán J
authors.initials: KJ
authors.lastname: Szabó
mesh_terms: D000588:Amines / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D005461:Fluorine / Q000737:chemistry*; D054879:Halogenation; D006571:Heterocyclic Compounds / Q000737:chemistry*; D007202:Indicators and Reagents / Q000737:chemistry; D007455:Iodine / Q000737:chemistry*
chemical_list: D000588:Amines; D006571:Heterocyclic Compounds; D007202:Indicators and Reagents; D005461:Fluorine; D003300:Copper; D007455:Iodine
keywords: copper; cyclizations; fluorine; heterocycles; homogeneous catalysis