title: Silver-Mediated N-Trifluoromethylation of Sulfoximines.
abstract: An unprecedented approach to N-trifluoromethylations of electron-rich nucleophilic sites following a radical pathway is reported. Accordingly, various sulfoximines (19 examples) have been N-trifluoromethylated, providing previously unreported products with satisfying functionality tolerance in moderate to good yields. With a C-N bond length at the N-CF3 moiety of 1.341 Å the respective linkage is shorter than a traditional C-N single bond and comparable with that of a C-N double bond.
authors.forename: Fan
authors.initials: F
authors.lastname: Teng
authors.affiliation: ‡Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, Aachen 52056, Germany.
authors.forename: Jiang
authors.initials: J
authors.lastname: Cheng
authors.affiliation: ‡Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, Aachen 52056, Germany.
authors.forename: Carsten
authors.initials: C
authors.lastname: Bolm
mesh_terms: D002384:Catalysis; D004852:Epoxy Compounds / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry; D015394:Molecular Structure; D012834:Silver / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D004852:Epoxy Compounds; D006845:Hydrocarbons, Fluorinated; D013438:Sulfhydryl Compounds; D012834:Silver