title: Quality of life in Japanese female patients with systemic lupus erythematosus: Evaluation using the Short Form 36 Health Survey.
abstract: OBJECTIVE
  Aspects of health-related quality of life (HRQoL) are important for assessing perceived health status and treatment burden. We evaluated HRQoL using Short Form 36 Health Survey (SF-36) and factors associated with HRQoL.
  
  
  METHODS
  We collected basic and lifestyle-related, clinical, and treatment characteristics among 119 female Japanese patients with systemic lupus erythematosus (SLE). Odds ratios (ORs) and their 95% confidence intervals were assessed for associations between HRQoL and selected factors.
  
  
  RESULTS
  Irregularity of sleep was significantly associated with risk of lower role physical (RP) (OR = 8.27), vitality (VT) (OR = 8.45), and role emotional (OR = 10.7) domains. Compared with clerical work, non-clerical work was significantly associated with risk of lower RP (OR = 7.39), and unemployment was significantly associated with risk of lower VT (OR = 41.0). Daily soybean intake was associated with improved General Health or GH (OR = 0.17). Compared with Systemic Lupus Collaborative Clinics Damage Index (SDI) = 0, SDI > 2 was associated with risk of lower PF (OR = 7.88), RP (OR = 4.29), and bodily pain (OR = 3.06) domains.
  
  
  CONCLUSIONS
  Reduced HRQoL was observed in our SLE patients. Interventions addressing sleep and work disturbances, as well as daily soybean consumption, could alter the HRQoL of SLE patients.
authors.affiliation: a Department of Medicine and Biosystemic Science , Kyushu University , Fukuoka , Japan.
authors.forename: Makio
authors.initials: M
authors.lastname: Furukawa
authors.affiliation: b Department of Preventive Medicine , Graduate School of Medical Sciences, Kyushu University , Fukuoka , Japan.
authors.forename: Chikako
authors.initials: C
authors.lastname: Kiyohara
authors.affiliation: c Department of Internal Medicine , Kyushu University Beppu Hospital , Oita , Japan 4 Department of Clinical Reserch , Fukuoka National Hospital , Fukuoka , Japan.
authors.forename: Takahiko
authors.initials: T
authors.lastname: Horiuchi
authors.affiliation: a Department of Medicine and Biosystemic Science , Kyushu University , Fukuoka , Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsukamoto
authors.affiliation: a Department of Medicine and Biosystemic Science , Kyushu University , Fukuoka , Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Mitoma
authors.affiliation: a Department of Medicine and Biosystemic Science , Kyushu University , Fukuoka , Japan.
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Kimoto
authors.affiliation: a Department of Medicine and Biosystemic Science , Kyushu University , Fukuoka , Japan.
authors.forename: Ayumi
authors.initials: A
authors.lastname: Uchino
authors.affiliation: a Department of Medicine and Biosystemic Science , Kyushu University , Fukuoka , Japan.
authors.forename: Misato
authors.initials: M
authors.lastname: Nakagawa
authors.affiliation: a Department of Medicine and Biosystemic Science , Kyushu University , Fukuoka , Japan.
authors.forename: Kensuke
authors.initials: K
authors.lastname: Oryoji
authors.affiliation: c Department of Internal Medicine , Kyushu University Beppu Hospital , Oita , Japan 4 Department of Clinical Reserch , Fukuoka National Hospital , Fukuoka , Japan.
authors.forename: Terufumi
authors.initials: T
authors.lastname: Shimoda
authors.affiliation: a Department of Medicine and Biosystemic Science , Kyushu University , Fukuoka , Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Akashi
mesh_terms: D000328:Adult; D004032:Diet; D004644:Emotions / Q000502:physiology; D005260:Female; D006304:Health Status; D006306:Health Surveys; D006801:Humans; D008019:Life Style; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000523:psychology*; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D012720:Severity of Illness Index; D012890:Sleep / Q000502:physiology; D013025:Glycine max
keywords: Female; Japanese; Quality of life; SF-36; Systemic lupus erythematosus