title: FoxM1: a novel tumor biomarker of lung cancer.
abstract: FoxM1 is a member of the Forkhead box (Fox) family of transcription factors, which is expressed in actively dividing cells and is critical for cell cycle progression. Increased expression of FoxM1 was found in many tumors including non-small cell lung cancer (NSCLC). A more recent study showed FoxM1 is associated with poor prognosis of NSCLC patients through promoting tumor metastasis; elucidated FoxM1 could exert a direct effect on the prognosis of NSCLCs patients. In this review, we summarize the role FoxM1 in lung cancer in the hope of providing insights into the utility of FoxM1 as a novel biomarker of lung cancer.
authors.affiliation: Department of Surgical Oncology, First Affiliated Hospital, Xi'an Jiaotong University 277# West Yantan Road, Xi'an 710061, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Surgical Oncology, First Affiliated Hospital, Xi'an Jiaotong University 277# West Yantan Road, Xi'an 710061, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Surgical Oncology, First Affiliated Hospital, Xi'an Jiaotong University 277# West Yantan Road, Xi'an 710061, China.
authors.forename: Xiaohai
authors.initials: X
authors.lastname: Cui
authors.affiliation: Department of Surgical Oncology, First Affiliated Hospital, Xi'an Jiaotong University 277# West Yantan Road, Xi'an 710061, China.
authors.forename: Ya
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Surgical Oncology, First Affiliated Hospital, Xi'an Jiaotong University 277# West Yantan Road, Xi'an 710061, China.
authors.forename: Min
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Surgical Oncology, First Affiliated Hospital, Xi'an Jiaotong University 277# West Yantan Road, Xi'an 710061, China.
authors.forename: Jingkun
authors.initials: J
authors.lastname: Qu
authors.affiliation: Department of Surgical Oncology, First Affiliated Hospital, Xi'an Jiaotong University 277# West Yantan Road, Xi'an 710061, China ; Deparment of Thoracic Surgery, The Nucleus Industry 215 Hospital 35# West Weiyang Road, Xianyang 712000, China.
authors.forename: Junhai
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Surgical Oncology, First Affiliated Hospital, Xi'an Jiaotong University 277# West Yantan Road, Xi'an 710061, China.
authors.forename: Jiansheng
authors.initials: J
authors.lastname: Wang
keywords: FoxM1; biomarker; lung cancer