title: Ru-Catalyzed Regioselective CH-Hydroarylation of Alkynes with Benzylthioethers Using Sulfur as Directing Group.
abstract: Benzylthioethers react with internal alkynes in the presence of catalytic amounts of [Ru(cymene)Cl2]2 to give the corresponding ortho-alkenylated species, using sulfur as the sole directing group. The reaction is regiospecific, tolerates different substituents at both the sulfur and the aryl ring, and proceeds very efficiently with a large variety of electron-rich alkynes.
authors.affiliation: Instituto de Síntesis Química y Catálisis Homogénea, ISQCH CSIC, Universidad de Zaragoza, Pedro Cerbuna 12, 50009 Zaragoza, Spain.
authors.forename: Pedro
authors.initials: P
authors.lastname: Villuendas
authors.affiliation: Instituto de Síntesis Química y Catálisis Homogénea, ISQCH CSIC, Universidad de Zaragoza, Pedro Cerbuna 12, 50009 Zaragoza, Spain.
authors.forename: Esteban P
authors.initials: EP
authors.lastname: Urriolabeitia