title: Assessing the histological type and grade of primary parotid carcinoma by fine-needle aspiration and frozen section.
abstract: OBJECTIVE
  The aim of this study is to compare preoperative fine needle aspiration cytology (FNAC) and intraoperative frozen section (FS) for the correct identification of malignancy, histological grade, and histological type.
  
  
  METHODS
  FNAC was performed on all 105 patients and FS on 71 patients with parotid carcinoma.
  
  
  RESULTS
  The rate of correctly determining the histological grade by FNAC and FS was 32% and 73%, respectively. The correct diagnosis rate for both the histological type and grade by FNAC and FS was 20% and 48%, respectively.
  
  
  CONCLUSIONS
  The correct grading of both high and low/intermediate grade carcinoma is possible in 70-80% of patients by FS. If the histological grade is identified correctly, the extent of resection can usually be decided appropriately. Therefore, we should put emphasis on determining the histological grade.
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Osaka Medical College, Takatsuki, Japan. Electronic address: oto055@poh.osaka-med.ac.jp.
authors.forename: Shuji
authors.initials: S
authors.lastname: Nishikawa
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Osaka Medical College, Takatsuki, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Kawata
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Osaka Medical College, Takatsuki, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Higashino
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Osaka Medical College, Takatsuki, Japan.
authors.forename: Koutetsu
authors.initials: K
authors.lastname: Lee
authors.affiliation: Department of Otolaryngology and Head and Neck Surgery, Osaka Medical College, Takatsuki, Japan.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Terada
authors.affiliation: Division of Surgical Pathology, Osaka Medical College, Takatsuki, Japan.
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Kurisu
authors.affiliation: Division of Surgical Pathology, Osaka Medical College, Takatsuki, Japan.
authors.forename: Motomu
authors.initials: M
authors.lastname: Tsuji
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology*; D044963:Biopsy, Fine-Needle; D018267:Carcinoma, Acinar Cell / Q000175:diagnosis / Q000473:pathology; D003528:Carcinoma, Adenoid Cystic / Q000175:diagnosis / Q000473:pathology; D044584:Carcinoma, Ductal / Q000175:diagnosis / Q000473:pathology; D018277:Carcinoma, Mucoepidermoid / Q000175:diagnosis / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology*; D015331:Cohort Studies; D003536:Cystadenocarcinoma / Q000175:diagnosis / Q000473:pathology; D005629:Frozen Sections; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D009208:Myoepithelioma / Q000175:diagnosis / Q000473:pathology; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D010307:Parotid Neoplasms / Q000175:diagnosis / Q000473:pathology*; D012189:Retrospective Studies; D000077195:Squamous Cell Carcinoma of Head and Neck
keywords: Fine-needle aspiration cytology; Frozen section; Histological grade; Histological type; Parotid carcinoma