title: Arenavirus Coinfections Are Common in Snakes with Boid Inclusion Body Disease.
abstract: Recently, novel arenaviruses were found in snakes with boid inclusion body disease (BIBD); these form the new genus Reptarenavirus within the family Arenaviridae. We used next-generation sequencing and de novo sequence assembly to investigate reptarenavirus isolates from our previous study. Four of the six isolates and all of the samples from snakes with BIBD contained at least two reptarenavirus species. The viruses sequenced comprise four novel reptarenavirus species and a representative of a new arenavirus genus.
authors.affiliation: University of Helsinki, Department of Virology, Haartman Institute, Helsinki, Finland jussi.hepojoki@helsinki.fi.
authors.forename: J
authors.initials: J
authors.lastname: Hepojoki
authors.affiliation: Blueprint Genetics, Helsinki, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Salmenperä
authors.affiliation: University of Helsinki, Department of Virology, Haartman Institute, Helsinki, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Sironen
authors.affiliation: Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
authors.forename: U
authors.initials: U
authors.lastname: Hetzel
authors.affiliation: University of Helsinki, Department of Virology, Haartman Institute, Helsinki, Finland.
authors.forename: Y
authors.initials: Y
authors.lastname: Korzyukov
authors.affiliation: Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zürich, Zürich, Switzerland Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Kipar
authors.affiliation: University of Helsinki, Department of Virology, Haartman Institute, Helsinki, Finland Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland Department of Virology and Immunology, University of Helsinki, Hospital District of Helsinki and Uusimaa, Helsinki, Finland.
authors.forename: O
authors.initials: O
authors.lastname: Vapalahti
mesh_terms: D000818:Animals; D001116:Arenaviridae / Q000145:classification / Q000235:genetics*; D001483:Base Sequence; D017821:Boidae / Q000821:virology*; D060085:Coinfection / Q000821:virology*; D014644:Genetic Variation; D059014:High-Throughput Nucleotide Sequencing; D007181:Inclusion Bodies, Viral / Q000473:pathology*; D016013:Likelihood Functions; D008957:Models, Genetic; D008969:Molecular Sequence Data; D010802:Phylogeny; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013045:Species Specificity