title: Supporting Biomaterials for Articular Cartilage Repair.
abstract: Orthopedic surgeons and researchers worldwide are continuously faced with the challenge of regenerating articular cartilage defects. However, until now, it has not been possible to completely mimic the biological and biochemical properties of articular cartilage using current research and development approaches. In this review, biomaterials previously used for articular cartilage repair research are addressed. Furthermore, a brief discussion of the state of the art of current cell printing procedures mimicking native cartilage is offered in light of their use as future alternatives for cartilage tissue engineering. Inkjet cell printing, controlled deposition cell printing tools, and laser cell printing are cutting-edge techniques in this context. The development of mimetic hydrogels with specific biological properties relevant to articular cartilage native tissue will support the development of improved, functional, and novel engineered tissue for clinical application.
authors.affiliation: Department of Dental Materials and Biomaterials Research, RWTH Aachen University Hospital, Aachen, Germany.
authors.forename: Daniela Filipa
authors.initials: DF
authors.lastname: Duarte Campos
authors.affiliation: Department of Orthopedics Surgery, RWTH Aachen University Hospital, Aachen, Germany.
authors.forename: Wolf
authors.initials: W
authors.lastname: Drescher
authors.affiliation: Department of Orthopedics Surgery, RWTH Aachen University Hospital, Aachen, Germany.
authors.forename: Björn
authors.initials: B
authors.lastname: Rath
authors.affiliation: Department of Orthopedics Surgery, RWTH Aachen University Hospital, Aachen, Germany.
authors.forename: Markus
authors.initials: M
authors.lastname: Tingart
authors.affiliation: Department of Dental Materials and Biomaterials Research, RWTH Aachen University Hospital, Aachen, Germany.
authors.forename: Horst
authors.initials: H
authors.lastname: Fischer
keywords: articular cartilage; biomaterials; bioprinting; tissue engineering