title: An efficient transformation of primary halides into nitriles through palladium-catalyzed hydrogen transfer reaction.
abstract: Two-step one-pot transformation of primary halides into corresponding nitriles is successfully achieved. Nucleophilic substitution of primary halides with sodium azide and subsequent palladium-catalyzed hydrogen transfer proceeds smoothly in the presence of sterically bulky ligand dicyclohexyl(2',4',6'-triisopropylbiphenyl-2-yl)phosphine (XPhos) in acetone to produce nitriles in satisfactory to good yields.
authors.affiliation: State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116023, China. mingbao@dlut.edu.cn.
authors.forename: Tao
authors.initials: T
authors.lastname: Zou
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Yu
authors.forename: Xiujuan
authors.initials: X
authors.lastname: Feng
authors.forename: Ming
authors.initials: M
authors.lastname: Bao