title: Youden's Index and the Likelihood Ratio Positive in Diagnostic Testing.
abstract: We refer to a recent letter to the editor by Hughes and show that, despite existing similarities between Youden's index and the log-likelihood ratio positive, important differences between these two measures remain to exist which can play an important difference in clinical practice.
authors.affiliation: Dankmar Böhning, Professor in Medical Statistics, Southampton Statistical Sciences Research Institute, University of Southampton, Building 39, Room 3019, Southampton SO17 1BJ, UK, E-mail: d.a.bohning@soton.ac.uk.
authors.forename: D
authors.initials: D
authors.lastname: Böhning
mesh_terms: D003955:Diagnostic Tests, Routine; D006801:Humans
keywords: Taylor series approxima-tion; Youden’s index; diagnostic testing; likelihood ratio positive