title: "Getting off the Bus Closer to Your Destination": Patients' Views about Pharmacogenetic Testing.
abstract: The authors conducted focus groups with patients prescribed antidepressants (pilot session plus 2 focus groups, n = 27); patients prescribed carbamazepine (2 focus groups, n = 17); and healthy patients (2 focus groups, n = 17). Although participants understood the potential advantages of pharmacogenetic testing, many felt that the risks (discrimination, stigmatization, physician overreliance on genomic results, and denial of certain medications) may outweigh the benefits. These concerns were shared across groups but were more strongly expressed among participants with chronic mental health diagnoses.
authors.affiliation: Research Scientist in Bioethics and Humanities at the University of Washington in Seattle. sbtrini@uw.edu.
authors.forename: Susan Brown
authors.initials: SB
authors.lastname: Trinidad
authors.affiliation: Doctoral Candidate in the Institute for Public Health Genetics at the University of Washington in Seattle. tarabethanne@gmail.com.
authors.forename: Tara B
authors.initials: TB
authors.lastname: Coffin
authors.affiliation: Associate Professor in Bioethics and Humanities at the University of Washington in Seattle. smfllrtn@uw.edu.
authors.forename: Stephanie M
authors.initials: SM
authors.lastname: Fullerton
authors.affiliation: Associate Investigator at the Group Health Research Institute in Seattle, WA. ralston.j@ghc.org.
authors.forename: James
authors.initials: J
authors.lastname: Ralston
authors.affiliation: Professor and Head of the Division of Medical Genetics at the University of Washington in Seattle. pair@uw.edu.
authors.forename: Gail P
authors.initials: GP
authors.lastname: Jarvik
authors.affiliation: Executive Director and Senior Investigator at the Group Health Research Institute in Seattle, WA. larson.e@ghc.org.
authors.forename: Eric B
authors.initials: EB
authors.lastname: Larson
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use; D005260:Female; D017144:Focus Groups; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D017060:Patient Satisfaction; D010597:Pharmacogenetics; D010817:Physician-Patient Relations; D036301:Qualitative Research; D011787:Quality of Health Care; D057545:Social Stigma
chemical_list: D000928:Antidepressive Agents