title: T-wave oversensing in patients with Brugada syndrome: true bipolar versus integrated bipolar implantable cardioverter defibrillator leads: multicenter retrospective study.
abstract: BACKGROUND
  It is thought that dedicated bipolar are more susceptible to T-wave oversensing when compared with integrated bipolar leads. This could be of extreme importance in patients with Brugada syndrome (BrS) because T-wave oversensing in this population is more frequent when compared with other implantable cardioverter defibrillator (ICD) recipients without BrS. We aimed to compare the incidence of T-wave oversensing in patients with BrS according to the type of lead (integrated bipolar versus true/dedicated bipolar).
  
  
  RESULTS
  All patients diagnosed with BrS with an ICD implant in 10 tertiary hospitals between 1993 and 2013 were included in the study. A total of 480 patients were included (mean age, 45.6±14 years). During a mean follow-up of 74.9±51.7 months (median, 69; range, 2-236), 28 patients had T-wave oversensing (5.8%), leading to inappropriate shock in 18 (3.8%). All these events occurred in patients with true bipolar ICD leads (P=0.01) and in 2 patients it was solved instantaneously by changing the configuration from a dedicated to an integrated bipolar sensing configuration. In the stepwise multivariate models, only integrated bipolar ICD leads (hazard ratio, 0.34; 95% confidence interval, 0.171-0.675; P=0.002) was independent predictor of non-T-wave oversensing.
  
  
  CONCLUSIONS
  T-wave oversensing is a potential reason of inappropriate shocks in patients with BrS receiving ICDs. In the vast majority it can be solved by reprogramming. However, in some patients it still requires invasive intervention. Importantly, incidence is significantly lower using an integrated bipolar lead system when compared with a dedicated bipolar lead system and hence the latter should be routinely used in BrS cases.
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.). moirmanero@gmail.com.
authors.forename: Moisés
authors.initials: M
authors.lastname: Rodríguez-Mañero
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Carlo
authors.initials: C
authors.lastname: de Asmundis
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Frédéric
authors.initials: F
authors.lastname: Sacher
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Elena
authors.initials: E
authors.lastname: Arbelo
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Vincent
authors.initials: V
authors.lastname: Probst
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Jesús
authors.initials: J
authors.lastname: Castro-Hevia
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Philippe
authors.initials: P
authors.lastname: Maury
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Anne
authors.initials: A
authors.lastname: Rollin
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Pier
authors.initials: P
authors.lastname: Lambiase
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Ignacio
authors.initials: I
authors.lastname: García-Bolao
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Gian-Battista
authors.initials: GB
authors.lastname: Chierchia
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Kengo
authors.initials: K
authors.lastname: Fukushima Kusano
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Gourraud
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Richard
authors.initials: R
authors.lastname: Schilling
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Kamakura
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Martínez-Sande
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Michel
authors.initials: M
authors.lastname: Haïssaguerre
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: José Ramón
authors.initials: JR
authors.lastname: González-Juanatey
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Jose
authors.initials: J
authors.lastname: Brugada
authors.affiliation: From the Hospital Clínico Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain (M.R.-M., L.M.-S., J.R.G.-J.); Department of Cardiology, Vrije Universiteit Brussel (VUB), Brussels, Belgium (C.d.A., G.-B.C., P.B.); Bordeaux University Hospital, LIRYC Institute/INSERM 1045, Bordeaux, France (F.S., M.H.); Hospital Clínic Universitario de Barcelona, Institut du Thorax, Barcelona, Spain (E.A., J.B.); CHU de Nantes, Nantes, France (V.P., J.-B.G.); Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba (J.C.-H.); CHU de Toulouse, Toulouse, France (P.M., A.R.); St. Bartholomew's Hospital, London, United Kingdom (P.L., R.S.); Clinica Universidad de Navarra, Pamplona, Spain (I.G.-B.); and Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.F.-K., T.K.).
authors.forename: Pedro
authors.initials: P
authors.lastname: Brugada
mesh_terms: D053840:Brugada Syndrome / Q000503:physiopathology / Q000628:therapy*; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
keywords: Brugada syndrome; arrhythmias; cardiac; defibrillators; electric countershock; follow-up studies; implantable