title: IVF/ICSI frozen replacement cycles; every cycle? Opinion expressed after a systematic review of the literature.
abstract: OBJECTIVE
  To determine whether in vitro fertilization (IVF), frozen replacement cycles offer better outcomes than fresh cycles in order to support, or not, a possible shift towards total replacement of fresh IVF/intracytoplasmic sperm injection (ICSI) cycles from frozen elective transfers (FETs).
  
  
  METHODS
  Systematic review; opinion paper.
  
  
  RESULTS
  Initial results seem to support a shift in current practice towards frozen cycles.
  
  
  CONCLUSIONS
  Initial results may support replacement all fresh IVF/ICSI cycles with FETs, as this could be a safer and equally effective strategy. However, robust evidence from randomized controlled trials is needed if this will be generally applied.
authors.forename: T
authors.initials: T
authors.lastname: Kalampokas
authors.forename: C
authors.initials: C
authors.lastname: Sofoudis
authors.forename: I
authors.initials: I
authors.lastname: Boutas
authors.forename: L
authors.initials: L
authors.lastname: Aravantinos
authors.forename: E
authors.initials: E
authors.lastname: Kalampokas
authors.forename: E
authors.initials: E
authors.lastname: Deligeoroglou
mesh_terms: D015925:Cryopreservation; D004624:Embryo Transfer; D004622:Embryo, Mammalian; D005260:Female; D005307:Fertilization in Vitro; D005615:Freezing; D006801:Humans; D011247:Pregnancy; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic