title: Surface-Enhanced Raman Spectroscopy-Based Approach for Ultrasensitive and Selective Detection of Hydrazine.
abstract: A probe mediated SERS-based strategy is developed to selectively detect hydrazine with superb sensitivity. Ortho-phthaldialdehyde, a simple probe, reacts specifically with hydrazine to form phthalazine, a molecule that possesses a larger Raman cross section and better affinity toward the SERS substrate. We observed a limit of detection of 8.5 × 10(-11) M. Our method shows both qualitative and quantitative measurement of hydrazine with high sensitivity, low cost, and fast analysis time.
authors.affiliation: Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
authors.forename: Xin
authors.initials: X
authors.lastname: Gu
authors.affiliation: Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States.
authors.forename: Jon P
authors.initials: JP
authors.lastname: Camden
mesh_terms: D006834:Hydrazines / Q000032:analysis*; D057230:Limit of Detection; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013499:Surface Properties
chemical_list: D006834:Hydrazines; C029424:hydrazine