title: Progress in research into the genes associated with venous thromboembolism.
abstract: BACKGROUND
  Venous thromboembolism (VTE), including both deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common, lethal disorder that affects hospitalized and non-hospitalized patients. This study aimed to review the progress in the research into VTE.
  
  
  METHODS
  We reviewed the studies about VTE and verified different genetic polymoriphisms of VTE.
  
  
  RESULTS
  The pathogenesis of VTE involves hereditary and acquired factors. Many studies indicated that the disorder of coagulation and fibirnolytic system is of utmost importance to this disease. Genetic polymoriphism-related VTE demonstrated significant differences among geographies and ethnicities.
  
  
  CONCLUSIONS
  VTE has many risk factors, but genetic factors play an important role.
authors.affiliation: Department of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
authors.forename: Lian-Xing
authors.initials: LX
authors.lastname: Zhao
authors.affiliation: Department of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
authors.forename: Chun-Sheng
authors.initials: CS
authors.lastname: Li
keywords: Gene; Hereditary; Polymoriphism; Venous thrombosis