title: Neuroleptic malignant syndrome in cycloserine-induced psychosis.
abstract: A 33-year-old multidrug-resistant tuberculosis female patient diagnosed as cycloserine-induced psychosis developed several neuroleptic side effects such as extrapyramidal reaction, neuroleptic malignant syndrome, and drug-induced parkinsonism while she was being treated with initially haloperidol and then olanzapine over a period of 2 months. Patient's antipsychotic medications were withdrawn, and treatment with bromocriptine showed prompt recovery. The multiple neurological adverse effects which the patient developed had implications on the management of the complications as well as her illness.
authors.affiliation: Department of Psychiatry, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India.
authors.forename: Neena S
authors.initials: NS
authors.lastname: Sawant
authors.affiliation: Department of Psychiatry, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India.
authors.forename: Natasha S
authors.initials: NS
authors.lastname: Kate
authors.affiliation: Department of Psychiatry, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India.
authors.forename: Swaroop S
authors.initials: SS
authors.lastname: Bhatankar
authors.affiliation: Department of Psychiatry, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India.
authors.forename: Prathamesh S
authors.initials: PS
authors.lastname: Kulkarni
mesh_terms: D000328:Adult; D000904:Antibiotics, Antitubercular / Q000009:adverse effects*; D000978:Antiparkinson Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001971:Bromocriptine / Q000627:therapeutic use; D003523:Cycloserine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009459:Neuroleptic Malignant Syndrome / Q000150:complications* / Q000188:drug therapy; D011605:Psychoses, Substance-Induced / Q000150:complications* / Q000188:drug therapy*
chemical_list: D000904:Antibiotics, Antitubercular; D000978:Antiparkinson Agents; D014150:Antipsychotic Agents; D001971:Bromocriptine; D003523:Cycloserine
keywords: Cycloserine; multidrug-resistant tuberculosis; neuroleptic malignant syndrome; parkinsonism