title: [A multicenter study on profile of hypertension in focal segmental glomerulosclerosis in Tunisia].
abstract: Hypertension in focal segmental glomerulosclerosis is frequent and responsible for the progression of the disease. It could be a circumstance of the diagnosis of FSG or a complication of the nephrotic syndrome.
  
  
  OBJECTIVE
  To determine the prevalence of hypertension among patients with FSG diagnosed in Tunisia and to describe the profile of patients with FSG having hypertension in contrast with who do not.
  
  
  METHODS
  It was a retrospective multicentric study based on 116 patient files having FSG located in 5 specialized centers in Tunisia.
  
  
  RESULTS
  The prevalence of hypertension among our patients was 41%, with a feminine predominance, their mean age was 36.34 ± 15.71 years. The systolic blood pressure among the patients with hypertension was 153.18 mmHg. The nephrotic syndrome was impure due to hypertension in 14.5% of the cases. The patients affected by hypertension were more obese. Proteinuria was higher among those not having hypertension than those with it, who score an average value of 5.67 ± 4.51 g/24h, with an insignificant difference. Serum creatinine at presentation was significantly higher among patients with hypertension. Vascular lesions were present at the renal biopsy among 39.45% of patients affected by hypertension, associated with renal failure in 58.50% of patients. The etiopathogenic treatment of FSG was essentially based on steroids full dose.
  
  
  CONCLUSIONS
  Hypertension is often present in FSG and its' treatment must be as soon as possible in order to slow the progression of kidney chronic disease.
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Fattouma Bourguiba, avenue Farhat Hached, 5000 Monastir, Tunisie. Electronic address: manel.ghali@yahoo.fr.
authors.forename: M
authors.initials: M
authors.lastname: Ghali
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Fattouma Bourguiba, avenue Farhat Hached, 5000 Monastir, Tunisie.
authors.forename: S
authors.initials: S
authors.lastname: Aloui
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Fattouma Bourguiba, avenue Farhat Hached, 5000 Monastir, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Letaief
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Fattouma Bourguiba, avenue Farhat Hached, 5000 Monastir, Tunisie.
authors.forename: M
authors.initials: M
authors.lastname: Hamouda
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Fattouma Bourguiba, avenue Farhat Hached, 5000 Monastir, Tunisie.
authors.forename: H
authors.initials: H
authors.lastname: Skhiri
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Fattouma Bourguiba, avenue Farhat Hached, 5000 Monastir, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Frih
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Hédi Chaker, Sfax, Tunisie.
authors.forename: J
authors.initials: J
authors.lastname: Hachicha
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU La Rabta, Tunis, Tunisie.
authors.forename: F
authors.initials: F
authors.lastname: Ben Moussa
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Sahloul, Sousse, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Achour
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Charles-Nicolle, Tunis, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Kheder
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Fattouma Bourguiba, avenue Farhat Hached, 5000 Monastir, Tunisie.
authors.forename: N
authors.initials: N
authors.lastname: Ben Dhia
authors.affiliation: Service de néphrologie et d'hémodialyse, CHU Fattouma Bourguiba, avenue Farhat Hached, 5000 Monastir, Tunisie.
authors.forename: M
authors.initials: M
authors.lastname: El May
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D014416:Tunisia / Q000453:epidemiology; D055815:Young Adult
keywords: Corticothérapie; Focal segmental glomerulosclerosis; HSF; HTA; Hypertension; Insuffisance rénale; Nephrotic syndrome; Renal failure; Steroids; Syndrome néphrotique