title: [Dutch trial results drive a major change in stroke care].
abstract: Recent randomised clinical trials have convincingly shown that endovascular therapy with the use of a retrievable stent considerably improves the chance of a good outcome in selected patients with acute ischaemic stroke and an occlusion of a proximal intracranial artery in the anterior circulation. The benefit of treatment strongly increases with shorter delays to reperfusion. This has major implications for the organisation of stroke care in the Netherlands. Agreements between all relevant parties are required in each region regarding the rapid referral of eligible patients to intervention centres. CT angiography must now become part of the standard evaluation of all patients with suspected ischaemic stroke presenting within six hours of symptom onset in order to achieve appropriate patient selection. Attention should be paid to workflow efficiencies to reduce delays. Since only a small proportion of stroke patients is eligible for endovascular therapy, the development of additional stroke therapies remains essential.
authors.affiliation: Universitair Medisch Centrum Utrecht, Hersencentrum Rudolf Magnus, afd. Neurologie en Neurochirurgie, Utrecht.
authors.forename: H Bart
authors.initials: HB
authors.lastname: van der Worp
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D009426:Netherlands; D017063:Outcome Assessment, Health Care; D018579:Patient Selection; D012017:Referral and Consultation; D015607:Stents; D020521:Stroke / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D015912:Thrombolytic Therapy