title: VARIATION OF 24-HOUR INTRAOCULAR PRESSURE IN SILICONE OIL-FILLED EYES.
abstract: OBJECTIVE
  To evaluate the variation of 24-hour intraocular pressure (IOP) in silicone oil (SO)-filled eyes.
  
  
  METHODS
  Prospective, nonrandomized comparative case series of 42 eyes of 21 patients, each with an SO-filled eye after vitrectomy. The fellow eyes served as controls. Each subject slept the usual 8 hours, and IOPs were measured at 4-hour intervals over 24 hours, twice before sleep (5:30 and 9:30 PM), twice during sleep (1:30 and 5:30 AM), and twice after sleep (9.30 AM and 1:30 PM). Intraocular pressure was measured in the sitting position using a Goldmann applanation tonometer. The SO-filled eyes and fellow eyes were compared with respect to diurnal-to-nocturnal and nocturnal-to-diurnal IOP changes.
  
  
  RESULTS
  At all 6 time points, SO-filled eyes had higher mean IOPs than fellow eyes (all P < 0.05). For both groups, mean nocturnal IOP was higher than mean diurnal IOP (both P < 0.001). Changes in diurnal-to-nocturnal IOP and nocturnal-to-diurnal IOP between SO-filled eyes and fellow eyes did not differ significantly (P > 0.05, respectively). The peak IOP occurred in the nocturnal period for all fellow eyes and for 94.7% of SO-filled eyes.
  
  
  CONCLUSIONS
  The IOP of SO-filled eyes varied over a 24-hour period, peaking largely in the nocturnal period, as observed for the IOP of fellow eyes.
authors.affiliation: Department of Ophthalmology, Graduate School of Medicine, Kyungpook National University, Daegu, South Korea.
authors.forename: Joo Hyun
authors.initials: JH
authors.lastname: Chang
authors.forename: Jae Pil
authors.initials: JP
authors.lastname: Shin
authors.forename: In Taek
authors.initials: IT
authors.lastname: Kim
authors.forename: Dong Ho
authors.initials: DH
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D002940:Circadian Rhythm / Q000502:physiology*; D058450:Endotamponade; D005129:Eye Foreign Bodies / Q000601:surgery; D005260:Female; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012827:Silicone Oils; D014065:Tonometry, Ocular; D014821:Vitrectomy; D057586:Vitreoretinal Surgery
chemical_list: D012827:Silicone Oils