title: [Blood serum cholecystokinin and clinical-functional variability of biliary pathology].
abstract: RESULTS
  Basal and stimulated serum CCK concentrations were not statistically significant differences (p > 0.05) with the control group in patients studied in the whole and in patients subgroups, formed by the diagnosis of biliary pathology and the character of gallbladder emptying. Increased stimulated CCK concentration was found in patients with symptomatic variants. Reduce of serum-cholecystokinin concentration growth (ACCK) after intake of Sorbitol was revealed in subgroup of patients with low-symptom variant. Reduced sensitivity of the gallbladder to CCK was observed in subgroups of patients with gallbladder hypokinetic dyskinesia and one with symptomatic variant of biliary pathology.
  
  
  CONCLUSIONS
  The sensitivity of the gallbladder neuromuscular apparatus to CCK is associated with clinical and functional variability of the biliary pathology.
authors.forename: L M
authors.initials: LM
authors.lastname: Nemtsov
mesh_terms: D000328:Adult; D001660:Biliary Tract Diseases / Q000097:blood* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016022:Case-Control Studies; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016473:Gallbladder Emptying / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012844:Sincalide / Q000031:analogs & derivatives* / Q000097:blood; D014463:Ultrasonography
chemical_list: C044201:cholecystokinin (26-33); D012844:Sincalide