title: [Clinical recommendations for diagnosis, treatment and monitoring of patients with cancer of unknown primary site].
abstract: Cancer of unknown primary (CUP) site comprises very heterogeneous group of various malignant tumors presented in metastatic phase of the disease. Diagnosis is set when primary site remains unidentified after a thorough diagnostic evaluation in patients with histologically proven malignant metastatic disease. Despite poor prognosis in most patients, favorable prognostic clinical entities have been recognized constituting the most important group of patients for oncological treatment. The following text presents the clinical guidelines in order to standardize the diagnosis, treatment and follow-up of patients with cancer of unknown primary site in the Republic of Croatia.
authors.forename: Vesna
authors.initials: V
authors.lastname: Bišof
authors.forename: Antonio
authors.initials: A
authors.lastname: Juretić
authors.forename: Dragan
authors.initials: D
authors.lastname: Trivanović
authors.forename: Renata Dobrila
authors.initials: RD
authors.lastname: Dintinjana
authors.forename: Božena
authors.initials: B
authors.lastname: Sarçević
authors.forename: Jasminka
authors.initials: J
authors.lastname: Jakić-Razumović
authors.forename: Marija
authors.initials: M
authors.lastname: Ban
authors.forename: Lidija
authors.initials: L
authors.lastname: Bošković
authors.forename: Branka--Petrić
authors.initials: B-
authors.lastname: Mise
authors.forename: Miljenko
authors.initials: M
authors.lastname: Bura
authors.forename: Dinko
authors.initials: D
authors.lastname: Stančić-Rokotov
mesh_terms: D017523:Croatia; D006801:Humans; D009382:Neoplasms, Unknown Primary / Q000175:diagnosis* / Q000628:therapy*; D011379:Prognosis