title: The vascular health status of a population of adult Canadian Indigenous peoples from British Columbia.
abstract: Indigenous populations currently experience greater cardiovascular disease burdens. However, subclinical vascular structure and function among these populations is not well known. This investigation evaluated vascular structure and function among Canadian Indigenous populations. Blood pressure, body composition, pulse-wave velocity (PWV), baroreceptor sensitivity (BRS), arterial compliance and intima-media thickness (IMT) were measured. Vascular measures were evaluated across sexes and age groups. Vascular assessments were conducted among 55 Indigenous adults (38±18 years, 29 Female), including both First Nations (N=36) and Métis (N=19) individuals. Some differences in vascular measures were found between males and females, respectively (spectral BRS: 9.6±6.8 ms mm Hg(-1) vs 16.9±10.0 ms mm Hg(-1), P=0.01; small arterial compliance: 8.9±3.7 ml mm Hg(-1) × 100 vs 6.4±2.3 ml mm Hg(-1) × 100, P=0.004), with similar measures of overall IMT (0.61±0.14 mm vs 0.57±0.08 mm, P=0.19) and central PWV (5.7±2.5 m s(-1) vs 5.1±2.3 m s(-1), P=0.58). Greater IMT, and lower BRS and arterial compliance were identified among older adults. This relatively healthy population demonstrated healthy vascular measures, with poorer measures among older individuals.
authors.affiliation: Cardiovascular Physiology and Rehabilitation Laboratory, University of British Columbia, Vancouver, British Columbia, Canada.|Experimental Medicine Program, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.|Physical Activity Promotion and Chronic Disease Prevention Unit, Vancouver, British Columbia, Canada.
authors.forename: H J A
authors.initials: HJ
authors.lastname: Foulds
authors.affiliation: Physical Activity Promotion and Chronic Disease Prevention Unit, Vancouver, British Columbia, Canada.
authors.forename: S S D
authors.initials: SS
authors.lastname: Bredin
authors.affiliation: Cardiovascular Physiology and Rehabilitation Laboratory, University of British Columbia, Vancouver, British Columbia, Canada.|Experimental Medicine Program, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.|Physical Activity Promotion and Chronic Disease Prevention Unit, Vancouver, British Columbia, Canada.
authors.forename: D E R
authors.initials: DE
authors.lastname: Warburton
mesh_terms: D000328:Adult; D000367:Age Factors; D017704:Baroreflex; D001794:Blood Pressure; D001823:Body Composition; D001955:British Columbia; D059168:Carotid Intima-Media Thickness; D005260:Female; D006304:Health Status; D006801:Humans; D007198:Indians, North American; D008019:Life Style / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D063177:Pulse Wave Analysis; D012307:Risk Factors; D012737:Sex Factors; D014652:Vascular Diseases / Q000175:diagnosis / Q000208:ethnology* / Q000503:physiopathology; D059289:Vascular Stiffness; D055815:Young Adult