title: Aerobic Oxidative Cycloaddition of α-Chlorotosylhydrazones with Arylamines: General Chemoselective Construction of 1,4-Disubstituted and 1,5-Disubstituted 1,2,3-Triazoles under Metal-Free and Azide-Free Conditions.
abstract: A novel synthetic approach toward 1,4-disubstituted 1,2,3-triazoles and 1,5-disubstituted 1,2,3-triazoles by aerobic oxidative cycloaddition of α-chlorotosylhydrazone with primary aryl amine has been developed. Significantly, the reaction proceeds smoothly to afford 1,4-disubstituted 1,2,3-triazoles and 1,5-disubstituted 1,2,3-triazoles under catalyst-free, metal-free, azide-free, and peroxide-free conditions.
authors.forename: Hui-Wen
authors.initials: HW
authors.lastname: Bai
authors.forename: Zhong-Jian
authors.initials: ZJ
authors.lastname: Cai
authors.forename: Shun-Yi
authors.initials: SY
authors.lastname: Wang
authors.forename: Shun-Jun
authors.initials: SJ
authors.lastname: Ji
mesh_terms: D000588:Amines / Q000737:chemistry*; D003500:Cyclization; D006835:Hydrazones / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D014105:Tosyl Compounds / Q000737:chemistry*; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000588:Amines; D006835:Hydrazones; D014105:Tosyl Compounds; D014230:Triazoles