title: Spatial and temporal dynamics of visual search tasks distinguish subtypes of unilateral spatial neglect: Comparison of two cases with viewer-centered and stimulus-centered neglect.
abstract: We developed a computerised test to evaluate unilateral spatial neglect (USN) using a touchscreen display, and estimated the spatial and temporal patterns of visual search in USN patients. The results between a viewer-centered USN patient and a stimulus-centered USN patient were compared. Two right-brain-damaged patients with USN, a patient without USN, and 16 healthy subjects performed a simple cancellation test, the circle test, a visuomotor search test, and a visual search test. According to the results of the circle test, one USN patient had stimulus-centered neglect and a one had viewer-centered neglect. The spatial and temporal patterns of these two USN patients were compared. The spatial and temporal patterns of cancellation were different in the stimulus-centered USN patient and the viewer-centered USN patient. The viewer-centered USN patient completed the simple cancellation task, but paused when transferring from the right side to the left side of the display. Unexpectedly, this patient did not exhibit rightward attention bias on the visuomotor and visual search tests, but the stimulus-centered USN patient did. The computer-based assessment system provided information on the dynamic visual search strategy of patients with USN. The spatial and temporal pattern of cancellation and visual search were different across the two patients with different subtypes of neglect.
authors.affiliation: a Department of Rehabilitation Medicine , Keio University School of Medicine , Tokyo , Japan.|b Department of Rehabilitation Medicine , National Sanatorium Tama Zenshoen , Tokyo , Japan.|c Department of Rehabilitation Medicine , Tokyo Metropolitan Rehabilitation Hospital , Tokyo , Japan.
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Mizuno
authors.affiliation: d Department of Biosciences and Informatics , Keio University , Kanagawa , Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kato
authors.affiliation: a Department of Rehabilitation Medicine , Keio University School of Medicine , Tokyo , Japan.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Tsuji
authors.affiliation: a Department of Rehabilitation Medicine , Keio University School of Medicine , Tokyo , Japan.|c Department of Rehabilitation Medicine , Tokyo Metropolitan Rehabilitation Hospital , Tokyo , Japan.
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Shindo
authors.affiliation: a Department of Rehabilitation Medicine , Keio University School of Medicine , Tokyo , Japan.|e Department of Rehabilitation Medicine , Ichikawa City Rehabilitation Hospital , Chiba , Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Kobayashi
authors.affiliation: a Department of Rehabilitation Medicine , Keio University School of Medicine , Tokyo , Japan.
authors.forename: Meigen
authors.initials: M
authors.lastname: Liu
mesh_terms: D000368:Aged; D001288:Attention; D016022:Case-Control Studies; D003936:Diagnosis, Computer-Assisted; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010468:Perceptual Disorders / Q000145:classification* / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D013028:Space Perception; D062211:Spatio-Temporal Analysis; D020521:Stroke / Q000150:complications / Q000503:physiopathology*; D014796:Visual Perception
keywords: Allocentric neglect; Egocentric neglect; Hemi-neglect; Spatial reference frame; Visual attention