title: [Effects of different-frequency-electroacupuncture and moxibustion stimulation of "Neiguan" (PC 6) on arrhythmia in rabbits].
abstract: OBJECTIVE
  To observe the effect of different-frequency-electroacupuncture (EA) and moxibustion stimulation on rabbits' arrhythmias.
  
  
  METHODS
  Newzealand rabbits were randomly divided into arrhythmia model (n = 18), EA-3 Hz (n = 19), EA-20 Hz (n = 19), EA-100 Hz (n = 18) and moxibustion (n = 18) groups. The arrhythmia model was induced by intravenous injection of 25 μg/kg aconitine. EA (3 Hz, 20 Hz or 100 Hz, 3.5-4 V) or moxibustion was applied to bilateral "Neiguan" (PC 6) for 20 min and electrocardiogram (ECG) of the standard limb lead II was recorded by using a Biosignal Processing Instrument. The concentration of serum hypersensitive C reactive protein (hs-CRP) content was detected by using ELISA method.
  
  
  RESULTS
  Following EA intervention, the duration of aconitine-induced arrhythmia was significantly shorter in both EA-20 Hz and EA-100 Hz groups than in the model group (P < 0.05, P < 0.01), and the serum hs-CRP level in the EA-20 Hz group was significantly lower than that of the model group ( P < 0.05). No significant changes were found in the duration of arrhythmia in both EA-3 Hz and moxibustion groups, and in the serum hs-CRP level in the EA-3 Hz, EA-100.Hz and the moxibustion groups (P > 0. 05).
  
  
  CONCLUSIONS
  EA stimulation of PC 6 at 20 Hz and 100 Hz has an anti-arrhythmic effect in aconitine-induced arrhythmia rabbits.
authors.forename: Ling
authors.initials: L
authors.lastname: Chen
authors.forename: Jin-Sen
authors.initials: JS
authors.lastname: Xu
authors.forename: Cai-Lian
authors.initials: CL
authors.lastname: Lan
authors.forename: Xiao-Hua
authors.initials: XH
authors.lastname: Pan
mesh_terms: D015669:Acupuncture Points; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D002097:C-Reactive Protein / Q000378:metabolism; D003131:Combined Modality Therapy; D015671:Electroacupuncture / Q000295:instrumentation / Q000379:methods*; D004562:Electrocardiography; D006801:Humans; D008297:Male; D009071:Moxibustion; D011817:Rabbits
chemical_list: D002097:C-Reactive Protein