title: Some thermodynamical aspects of protein hydration water.
abstract: We study by means of nuclear magnetic resonance the self-diffusion of protein hydration water at different hydration levels across a large temperature range that includes the deeply supercooled regime. Starting with a single hydration shell (h = 0.3), we consider different hydrations up to h = 0.65. Our experimental evidence indicates that two phenomena play a significant role in the dynamics of protein hydration water: (i) the measured fragile-to-strong dynamic crossover temperature is unaffected by the hydration level and (ii) the first hydration shell remains liquid at all hydrations, even at the lowest temperature.
authors.affiliation: Dipartimento di Fisica e Scienze della Terra, Università di Messina and CNISM, I-98168 Messina, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Mallamace
authors.affiliation: Dipartimento di Fisica e Scienze della Terra, Università di Messina and CNISM, I-98168 Messina, Italy.
authors.forename: Carmelo
authors.initials: C
authors.lastname: Corsaro
authors.affiliation: Dipartimento SASTAS, Università di Messina, I-98166 Messina, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Mallamace
authors.affiliation: Dipartimento di Fisica e Scienze della Terra, Università di Messina and CNISM, I-98168 Messina, Italy.
authors.forename: Sebastiano
authors.initials: S
authors.lastname: Vasi
authors.affiliation: CNR-IPCF, Viale F. Stagno D'Alcontres 37, I-98158 Messina, Italy.
authors.forename: Cirino
authors.initials: C
authors.lastname: Vasi
authors.affiliation: Center for Polymer Studies and Department of Physics, Boston University, Boston, Massachusetts 02215, USA.
authors.forename: H Eugene
authors.initials: HE
authors.lastname: Stanley
authors.affiliation: Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
authors.forename: Sow-Hsin
authors.initials: SH
authors.lastname: Chen
mesh_terms: D011506:Proteins / Q000737:chemistry*; D013696:Temperature; D013816:Thermodynamics; D014867:Water / Q000737:chemistry*
chemical_list: D011506:Proteins; D014867:Water