title: [Personalized medicine in otology. The role of genetic diagnostics in patients with hearing impairment].
abstract: BACKGROUND
  Classification of diseases on the molecular level is the basis for personalized medicine. Personalized medicine proposes to improve efficiency and quality of care, to reduce side effects and to increase long-term cost-effectiveness.
  
  
  OBJECTIVE
  This paper is concerned with the role of genetic diagnostics in patients with a cochlear implant.
  
  
  METHODS
  A selective literature search in PubMed was performed.
  
  
  RESULTS
  Genetic diagnosis allows ruling out syndromic hearing loss and thus prevents follow-up studies. It allows genetic counseling, prognosis and advice on family planning and targeted prevention. Due to its minimal invasiveness, it is suitable for evaluation of factors accounting for hearing loss in children.
  
  
  CONCLUSIONS
  Molecular medicine plays a major role in the treatment of sensorineural hearings loss with cochlear implants.
authors.affiliation: Klinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Tübingen, Elfriede-Aulhorn-Straße 5, 72076, Tübingen, Deutschland.
authors.forename: N
authors.initials: N
authors.lastname: Friese
authors.forename: K
authors.initials: K
authors.lastname: Braun
authors.forename: M
authors.initials: M
authors.lastname: Müller
authors.forename: A
authors.initials: A
authors.lastname: Tropitzsch
mesh_terms: D003054:Cochlear Implants; D005817:Genetic Counseling / Q000639:trends*; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005820:Genetic Testing / Q000639:trends*; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000235:genetics* / Q000534:rehabilitation; D006801:Humans; D010036:Otolaryngology / Q000639:trends*; D057285:Precision Medicine / Q000639:trends*