title: Detection of telomerase on upconversion nanoparticle modified cellulose paper.
abstract: Herein we report a convenient and sensitive method for the detection of telomerase activity based on upconversion nanoparticle (UCNP) modified cellulose paper. Compared with many solution-phase systems, this paper chip is more stable and easily stores the test results. What's more, the low background fluorescence of the UCNPs increases the sensitivity of this method, and the low telomerase levels in different cell lines can clearly be discriminated by the naked eye.
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. xqu@ciac.ac.cn.
authors.forename: Faming
authors.initials: F
authors.lastname: Wang
authors.forename: Wen
authors.initials: W
authors.lastname: Li
authors.forename: Jiasi
authors.initials: J
authors.lastname: Wang
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry; D045744:Cell Line, Tumor; D002482:Cellulose; D005459:Fluorides / Q000737:chemistry; D057809:HEK293 Cells; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry; D009841:Oligonucleotides / Q000737:chemistry / Q000378:metabolism; D010209:Paper; D019098:Telomerase / Q000737:chemistry / Q000378:metabolism*; D015019:Yttrium / Q000737:chemistry
chemical_list: D000180:Acrylic Resins; D009841:Oligonucleotides; C525362:sodium yttriumtetrafluoride; C006903:carbopol 940; D015019:Yttrium; D002482:Cellulose; D019098:Telomerase; D005459:Fluorides