title: First Case of Ascaris lumbricoides Infestation Complicated with Hemophagocytic Lymphohistiocytosis.
abstract: Ascariasis is a common soil-transmitted helminth infestation worldwide. Ascaris lumbricoides infestation is generally asymptomatic or cause nonspecific signs and symptoms. We report a 5-year-old male with hemophagocytic lymphohistiocytosis associated with A. lumbricoides infestation. The presented patient recovered completely after defecating an A. lumbricoides following intravenous immunoglobulin (IVIG) and mebendazole treatment. We wanted to emphasize that because helminth infestation is easily overlooked, the diagnosis of ascariasis should be considered in patients who live in endemic areas and treated timely to prevent severe complications.
authors.affiliation: Division of Pediatric Infectious Diseases, Yüzüncü Yıl University, Van, Turkey. gbayhan@gmail.com.
authors.forename: Gülsüm İclal
authors.initials: Gİ
authors.lastname: Bayhan
authors.forename: Funda
authors.initials: F
authors.lastname: Çenesiz
authors.forename: Gönül
authors.initials: G
authors.lastname: Tanır
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Taylan Özkan
authors.forename: Gökçe
authors.initials: G
authors.lastname: Çınar
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000627:therapeutic use; D001196:Ascariasis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D017164:Ascaris lumbricoides / Q000187:drug effects / Q000302:isolation & purification; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005243:Feces / Q000469:parasitology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008463:Mebendazole / Q000627:therapeutic use
chemical_list: D000969:Antinematodal Agents; D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D008463:Mebendazole