title: Plasma biomarkers for early diagnosis of acute intestinal ischemia.
abstract: Determining the severity of acute mesenteric ischemia or reperfusion injury can be problematic, as early visceral hypoperfusion is difficult to detect by traditional laboratory testing. Likewise gauging the success of resuscitation and therapeutic intervention is also challenging to determine by laboratory analysis alone. Investigators continue to actively search for plasma biomarkers that will aide clinicians in identifying the early microvascular changes associated with visceral splanchnic malperfusion in an effort to allow for earlier diagnosis and expedient intervention in order to minimize overall intestinal ischemia and reperfusion injury for the potential of improving clinical outcomes.
authors.affiliation: Division of Vascular and Endovascular Surgery, University of South Florida College of Medicine, 2 Tampa General Circle, Suite 7001, Tampa, FL.
authors.forename: Alexis
authors.initials: A
authors.lastname: Powell
authors.affiliation: Division of Vascular and Endovascular Surgery, University of South Florida College of Medicine, 2 Tampa General Circle, Suite 7001, Tampa, FL. Electronic address: parmstro@health.usf.edu.
authors.forename: Paul
authors.initials: P
authors.lastname: Armstrong
mesh_terms: D000208:Acute Disease; D000818:Animals; D015415:Biomarkers / Q000097:blood*; D042241:Early Diagnosis; D006801:Humans; D065666:Mesenteric Ischemia / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D018579:Patient Selection; D011237:Predictive Value of Tests; D011379:Prognosis; D015427:Reperfusion Injury / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D012307:Risk Factors; D012720:Severity of Illness Index; D013152:Splanchnic Circulation
chemical_list: D015415:Biomarkers