title: Initial experience of using high field strength intraoperative MRI for neurosurgical procedures.
abstract: We report our initial experience to optimize neurosurgical procedures using high field strength intraoperative magnetic resonance imaging (IOMRI) in 300 consecutive patients as high field strength IOMRI rapidly becomes the standard of care for neurosurgical procedures. Three sequential groups (groups A, B, C; n=100 each) were compared with respect to time management, complications and technical difficulties to assess improvement in these parameters with experience. We observed a reduction in the number of technical difficulties (p<0.001), time to induction (p<0.001) and total anesthesia time (p=0.007) in sequential groups. IOMRI was performed for neuronavigation guidance (n=252) and intraoperative validation of extent of resection (EOR; n=67). Performing IOMRI increased the EOR over and beyond the primary surgical attempt in 20.5% (29/141) and 18% (11/61) of patients undergoing glioma and pituitary surgery, respectively. Overall, EOR improved in 59.7% of patients undergoing IOMRI (40/67). Intraoperative tractography and real time navigation using re-uploaded IOMRI images (accounting for brain shift) helps in intraoperative planning to reduce complications. IOMRI is an asset to neurosurgeons, helping to augment the EOR, especially in glioma and pituitary surgery, with no significant increase in morbidity to the patient.
authors.affiliation: Department of Neurosurgery and Gamma Knife, Neurosciences Centre, All India Institute of Medical Sciences, Room 8, Sixth Floor, Ansari Nagar, New Delhi 110029, India.
authors.forename: Amol
authors.initials: A
authors.lastname: Raheja
authors.affiliation: Department of Neurosurgery and Gamma Knife, Neurosciences Centre, All India Institute of Medical Sciences, Room 8, Sixth Floor, Ansari Nagar, New Delhi 110029, India. Electronic address: drtandonvivek@gmail.com.
authors.forename: Vivek
authors.initials: V
authors.lastname: Tandon
authors.affiliation: Department of Neurosurgery and Gamma Knife, Neurosciences Centre, All India Institute of Medical Sciences, Room 8, Sixth Floor, Ansari Nagar, New Delhi 110029, India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Suri
authors.affiliation: Department of Neurosurgery and Gamma Knife, Neurosciences Centre, All India Institute of Medical Sciences, Room 8, Sixth Floor, Ansari Nagar, New Delhi 110029, India.
authors.forename: P
authors.initials: P
authors.lastname: Sarat Chandra
authors.affiliation: Department of Neurosurgery and Gamma Knife, Neurosciences Centre, All India Institute of Medical Sciences, Room 8, Sixth Floor, Ansari Nagar, New Delhi 110029, India.
authors.forename: Shashank S
authors.initials: SS
authors.lastname: Kale
authors.affiliation: Department of Neuro-radiology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Ajay
authors.initials: A
authors.lastname: Garg
authors.affiliation: Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Ravindra M
authors.initials: RM
authors.lastname: Pandey
authors.affiliation: Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Mani
authors.initials: M
authors.lastname: Kalaivani
authors.affiliation: Department of Neurosurgery and Gamma Knife, Neurosciences Centre, All India Institute of Medical Sciences, Room 8, Sixth Floor, Ansari Nagar, New Delhi 110029, India.
authors.forename: Ashok K
authors.initials: AK
authors.lastname: Mahapatra
authors.affiliation: Department of Neurosurgery and Gamma Knife, Neurosciences Centre, All India Institute of Medical Sciences, Room 8, Sixth Floor, Ansari Nagar, New Delhi 110029, India.
authors.forename: Bhawani S
authors.initials: BS
authors.lastname: Sharma
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D038361:Neuronavigation / Q000379:methods*; D019635:Neurosurgical Procedures / Q000379:methods*; D061646:Operative Time; D025321:Surgery, Computer-Assisted / Q000379:methods*
keywords: Critical analysis; High field strength; Intraoperative MRI; Neurosurgical procedures; Time management