title: Fibrinogen and catheter-directed thrombolysis.
abstract: Fibrinogen is a complex glycoprotein that is known to play a significant role in the process of thrombus formation and evolution, and has been linked to the pathophysiology of atherosclerosis. Given the importance of fibrinogen in these processes, it has been evaluated as a biomarker for atherosclerotic disease and as a marker during treatment for venous and arterial thrombosis. Here we describe the expansive role that fibrinogen plays in human physiology.
authors.affiliation: Division of Vascular Surgery and Endovascular Therapy, University of Florida College of Medicine, P.O. Box 100128, 1600 SW Archer Road, Suite NG-45, Gainesville, FL 32610-0128.
authors.forename: Reagan L
authors.initials: RL
authors.lastname: Ross
authors.affiliation: Division of Vascular Surgery and Endovascular Therapy, University of Florida College of Medicine, P.O. Box 100128, 1600 SW Archer Road, Suite NG-45, Gainesville, FL 32610-0128. Electronic address: adam.beck@surgery.ufl.edu.
authors.forename: Adam W
authors.initials: AW
authors.lastname: Beck
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D002406:Catheterization, Peripheral / Q000009:adverse effects / Q000592:standards; D005340:Fibrinogen / Q000235:genetics / Q000378:metabolism*; D005342:Fibrinolysis / Q000187:drug effects; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D017410:Practice Guidelines as Topic; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012307:Risk Factors; D013923:Thromboembolism / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics; D015912:Thrombolytic Therapy / Q000009:adverse effects / Q000379:methods* / Q000592:standards; D013927:Thrombosis / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D005343:Fibrinolytic Agents; D005340:Fibrinogen