title: Increased Ocular Pulse Amplitude Associated with Unilateral Dysgenesis of the Orbital Roof.
abstract: BACKGROUND
  Two patients (one with neurofibromatosis type 1) presented with unilateral ocular pulsation.
  
  
  METHODS
  A CT scan of the orbits revealed extensive dysgenesis of the orbital roof with herniation of the frontal lobe into the orbit in both cases. PASCAL dynamic contour tonometry was performed.
  
  
  RESULTS
  The ipsilateral ocular pulse amplitude (OPA) was greater than the contralateral side, and the ocular pulse waveform morphology more closely approximated the known intracranial waveform in these patients.
  
  
  CONCLUSIONS
  We hypothesize that the greater OPA was due to stronger transmission of the intracranial pressure waveform amplitude and morphology in the absence of the orbital roof.
authors.affiliation: Department of Ophthalmology, The Ohio State University, Columbus, Ohio, USA.
authors.forename: Ami Shah
authors.initials: AS
authors.lastname: Vira
authors.affiliation: Department of Ophthalmology, The Ohio State University, Columbus, Ohio, USA ; Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio, USA.
authors.forename: Ashraf M
authors.initials: AM
authors.lastname: Mahmoud
authors.affiliation: Department of Ophthalmology, The Ohio State University, Columbus, Ohio, USA ; Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio, USA.
authors.forename: Cynthia J
authors.initials: CJ
authors.lastname: Roberts
authors.affiliation: Department of Ophthalmology, The Ohio State University, Columbus, Ohio, USA ; Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio, USA.
authors.forename: Steven E
authors.initials: SE
authors.lastname: Katz
keywords: Cerebrospinal fluid pulse; Intracranial pressure; Ocular pulse amplitude; Orbital roof dysgenesis; Sphenoid wing dysplasia