title: Magnetic graphene as modified quick, easy, cheap, effective, rugged and safe adsorbent for the determination of organochlorine pesticide residues in tobacco.
abstract: In this study, magnetic graphene was used as modified quick, easy, cheap, effective, rugged and safe (QuEChERS) adsorbent for the determination of organochlorine pesticide (OCPs) residues in tobacco. To achieve the optimum conditions of modified QuEChERS procedure toward target analytes, several parameters affecting the clean-up efficiency including the amount of the adsorbent and clean-up time were investigated. Under the optimized conditions, a method for the determination of 26 OCPs residues in tobacco was established by coupling the modified QuEChERS procedure to on-line gel permeation chromatography-gas chromatography-tandem mass spectrometry (on-line GPC-GC-MS(2)). The limits of detection of proposed method for 26 OCPs residues ranged from 0.01275 to 3.150ng/g. And good linearities of the proposed method were obtained with coefficients of determination (R(2)) greater than 0.9985 for all target analytes. Good reproducibility of method was obtained as intra- and inter-day precisions, the relative standard deviations were less than 11.1 and 15.0%, respectively. The apparent recoveries were in the range of 64-126% at different concentrations for real samples. Compared with the reported methods for the determination of OCPs residues in tobacco, the proposed method has the advantages of simple to operate, low cost and high clean-up ability. Finally, the method was successfully applied to the analysis of OCPs residues in real samples.
authors.affiliation: China National Tobacco Quality Supervision and Test Center, No. 2 Fengyang Street, Zhengzhou High and New Technology Industries Development Zone, Zhengzhou 450001, China.
authors.forename: Yan-Bo
authors.initials: YB
authors.lastname: Luo
authors.affiliation: China National Tobacco Quality Supervision and Test Center, No. 2 Fengyang Street, Zhengzhou High and New Technology Industries Development Zone, Zhengzhou 450001, China.
authors.forename: Xue
authors.initials: X
authors.lastname: Li
authors.affiliation: China National Tobacco Quality Supervision and Test Center, No. 2 Fengyang Street, Zhengzhou High and New Technology Industries Development Zone, Zhengzhou 450001, China.
authors.forename: Xing-Yi
authors.initials: XY
authors.lastname: Jiang
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Department of Chemistry, Wuhan University, Wuhan 430072, China.
authors.forename: Bao-Dong
authors.initials: BD
authors.lastname: Cai
authors.affiliation: China National Tobacco Quality Supervision and Test Center, No. 2 Fengyang Street, Zhengzhou High and New Technology Industries Development Zone, Zhengzhou 450001, China.
authors.forename: Feng-Peng
authors.initials: FP
authors.lastname: Zhu
authors.affiliation: China National Tobacco Quality Supervision and Test Center, No. 2 Fengyang Street, Zhengzhou High and New Technology Industries Development Zone, Zhengzhou 450001, China.
authors.forename: Hong-Fei
authors.initials: HF
authors.lastname: Zhang
authors.affiliation: China National Tobacco Quality Supervision and Test Center, No. 2 Fengyang Street, Zhengzhou High and New Technology Industries Development Zone, Zhengzhou 450001, China.
authors.forename: Zai-Gen
authors.initials: ZG
authors.lastname: Chen
authors.affiliation: China National Tobacco Quality Supervision and Test Center, No. 2 Fengyang Street, Zhengzhou High and New Technology Industries Development Zone, Zhengzhou 450001, China. Electronic address: 36140501@qq.com.
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: Pang
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), Department of Chemistry, Wuhan University, Wuhan 430072, China.
authors.forename: Yu-Qi
authors.initials: YQ
authors.lastname: Feng
mesh_terms: D002623:Chemistry Techniques, Analytical / Q000191:economics / Q000379:methods*; D002850:Chromatography, Gel; D004785:Environmental Pollutants / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D006108:Graphite / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000032:analysis; D060328:Magnetic Phenomena; D010573:Pesticide Residues / Q000032:analysis*; D015203:Reproducibility of Results; D014026:Nicotiana / Q000737:chemistry*
chemical_list: D004785:Environmental Pollutants; D006843:Hydrocarbons, Chlorinated; D010573:Pesticide Residues; D006108:Graphite
keywords: Magnetic graphene; On-line gel permeation chromatography–gas chromatography/tandem mass spectrometry (on-line GPC–GC–MS(2)); Pesticide residues; QuEChERS; Tobacco