title: [Evaluations of olfactory function for myasthenia gravis patients].
abstract: OBJECTIVE
  To explore the olfactory function of patients with myasthenia gravis (MG) and analyze the correlation between olfactory dysfunction and clinical characteristics.
  
  
  METHODS
  A total of 61 MG patients from March to July 2014 and 32 healthy controls (HC) received T&T olfactometer test. Their clinical data were collected. And the relationship of T&T score and clinical characteristics were analyzed.
  
  
  RESULTS
  The identification threshold of T&T olfactometer test was (2.07±1.56) versus (0.31±1.25) for healthy controls. MG patients had a worse performance on olfaction test than healthy controls (t=5.50, P<0.01). By Spearman's analysis, disease course (r=0.348, P=0.006), QMG scores (r=0.393, P=0.025), ADL scores (r=0.421, P=0.01) and dosing time of pyridostigmine (r=0.295, P=0.025) were positively correlated with T&T scores. However, the dosing times of prednisone (r=0.084, P=0.053) or immunodepressants (r=0.153, P=0.251) were not correlated with T&T scores.
  
  
  CONCLUSIONS
  MG patients have poor olfactory sensation.And a potential involvement of non-motor system shall attract the attention of neurologists.
authors.affiliation: Department of Neurology, General Hospital & Tianjin Neurological Institute, Tianjin Medical University, Tianjin 300052, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Neurology, General Hospital & Tianjin Neurological Institute, Tianjin Medical University, Tianjin 300052, China; Email: yangli2001@tijmu.edu.cn.
authors.forename: Li
authors.initials: L
authors.lastname: Yang
authors.affiliation: Department of Neurology, General Hospital & Tianjin Neurological Institute, Tianjin Medical University, Tianjin 300052, China.
authors.forename: Linjie
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Neurology, General Hospital & Tianjin Neurological Institute, Tianjin Medical University, Tianjin 300052, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Fu
authors.affiliation: Department of Neurology, General Hospital & Tianjin Neurological Institute, Tianjin Medical University, Tianjin 300052, China.
authors.forename: Limin
authors.initials: L
authors.lastname: Li
mesh_terms: D018450:Disease Progression; D006801:Humans; D009157:Myasthenia Gravis; D009830:Olfactory Bulb; D012903:Smell