title: Interventional Radiologist's perspective on the management of bone metastatic disease.
abstract: Bone metastases can be treated by interventional radiologists with a minimally invasive approach. Such treatments are performed percutaneously under radiological imaging guidance. Different interventional techniques can be applied with curative or palliative intent depending on lesions and patients' status. In the whole, available interventional techniques are distinguished into "ablative" and "consolidative". Ablative techniques achieve bone tumor necrosis by dramatically increasing or decreasing intra-tumoral temperature. This option can be performed in order to alleviate pain or to eradicate the lesion. On the other hand, consolidative techniques aim at obtaining bone defect reinforcement mainly to alleviate pain and prevent pathological fractures. We herein present evidence supporting the application of each different interventional technique, as well as common strategies followed by interventional radiologists while approaching bone metastases.
authors.affiliation: Department of Radiology, Università "Campus Bio-Medico di Roma", Via Alvaro del Portillo 200, 00128, Rome, Italy. Electronic address: r.cazzato@unicampus.it.
authors.forename: R L
authors.initials: RL
authors.lastname: Cazzato
authors.affiliation: Department of Radiology, Institut Bergonié, 229 Cours de l'Argonne, 33000, Bordeaux, France. Electronic address: x.buy@bordeaux.unicancer.fr.
authors.forename: X
authors.initials: X
authors.lastname: Buy
authors.affiliation: Department of Radiology, Università "Campus Bio-Medico di Roma", Via Alvaro del Portillo 200, 00128, Rome, Italy. Electronic address: r.grasso@unicampus.it.
authors.forename: R F
authors.initials: RF
authors.lastname: Grasso
authors.affiliation: Department of Radiology, Università "Campus Bio-Medico di Roma", Via Alvaro del Portillo 200, 00128, Rome, Italy. Electronic address: g.luppi@unicampus.it.
authors.forename: G
authors.initials: G
authors.lastname: Luppi
authors.affiliation: Department of Radiology, Università "Campus Bio-Medico di Roma", Via Alvaro del Portillo 200, 00128, Rome, Italy. Electronic address: e.faiella@unicampus.it.
authors.forename: E
authors.initials: E
authors.lastname: Faiella
authors.affiliation: Department of Radiology, Università "Campus Bio-Medico di Roma", Via Alvaro del Portillo 200, 00128, Rome, Italy. Electronic address: c.quattrocchi@unicampus.it.
authors.forename: C C
authors.initials: CC
authors.lastname: Quattrocchi
authors.affiliation: Department of Medical Oncology, Università "Campus Bio-Medico di Roma", Via Alvaro del Portillo 200, 00128, Rome, Italy. Electronic address: f.pantano@unicampus.it.
authors.forename: F
authors.initials: F
authors.lastname: Pantano
authors.affiliation: Department of Radiology, Università "Campus Bio-Medico di Roma", Via Alvaro del Portillo 200, 00128, Rome, Italy. Electronic address: b.zobel@unicampus.it.
authors.forename: B
authors.initials: B
authors.lastname: Beomonte Zobel
authors.affiliation: Department of Medical Oncology, Università "Campus Bio-Medico di Roma", Via Alvaro del Portillo 200, 00128, Rome, Italy. Electronic address: g.tonini@unicampus.it.
authors.forename: G
authors.initials: G
authors.lastname: Tonini
authors.affiliation: Department of Medical Oncology, Università "Campus Bio-Medico di Roma", Via Alvaro del Portillo 200, 00128, Rome, Italy. Electronic address: d.santini@unicampus.it.
authors.forename: D
authors.initials: D
authors.lastname: Santini
authors.affiliation: Department of Radiology, Institut Bergonié, 229 Cours de l'Argonne, 33000, Bordeaux, France. Electronic address: j.palussiere@bordeaux.unicancer.fr.
authors.forename: J
authors.initials: J
authors.lastname: Palussiere
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary / Q000628:therapy; D003131:Combined Modality Therapy; D019468:Disease Management; D006801:Humans; D009362:Neoplasm Metastasis; D011859:Radiography; D015642:Radiology, Interventional / Q000379:methods*
keywords: Ablation; Bone; Cementoplasty; Interventional radiology; Metastasis