title: Bisphosphonate treatment of children and adults with osteogenesis imperfecta: unanswered questions.
abstract: Bisphosphonates are extensively used for treatment of children and adults with osteogenesis imperfecta. Over years, studies have reported the response of BP treatment in individuals with OI but some questions remain still unanswered.
authors.affiliation: Bone Disorders Program, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, 707 N. Broadway, Baltimore, MD, 21205, USA, Brizola@kennedykrieger.org.
authors.forename: Evelise
authors.initials: E
authors.lastname: Brizola
authors.forename: Jay Robert
authors.initials: JR
authors.lastname: Shapiro
mesh_terms: D000293:Adolescent; D000328:Adult; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D002648:Child; D004164:Diphosphonates / Q000627:therapeutic use*; D006801:Humans; D010013:Osteogenesis Imperfecta / Q000188:drug therapy*
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates