title: Multilocus Sequence Types of Campylobacter jejuni Isolates from Different Sources in Eastern China.
abstract: Campylobacter jejuni is a major food-borne pathogen that causes human gastroenteritis in many developed countries. In our study, we applied multilocus sequence typing (MLST) technology to 167 C. jejuni isolates from diverse sources in Eastern China to examine their genetic diversity. MLST defined 94 sequence types (STs) belonging to 18 clonal complexes (CCs). Forty-five STs from 60 isolates (36%) and 22 alleles have not been previously documented in an international database. One hundred and two isolates, accounting for 61.1% of all isolates, belonged to eight clonal complexes. The eight major CCs were also the most common complexes from different sources. The most common ST type of isolates from human and food was ST-353. The dominant ST type in chicken and foods was ST-354. Among 21 STs that contained two or more different sources isolates, 15 STs contained human isolates and isolates from other sources, suggesting that potentially pathogenic strains are not restricted to specific lineages.
authors.affiliation: Jiangsu Key Lab of Zoonosis, Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, 88 South Daxue Road, Yangzhou, 225009, Jiangsu, China.
authors.forename: Gong
authors.initials: G
authors.lastname: Zhang
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Zhang
authors.forename: Yuanqing
authors.initials: Y
authors.lastname: Hu
authors.forename: Xin-An
authors.initials: XA
authors.lastname: Jiao
authors.forename: Jinlin
authors.initials: J
authors.lastname: Huang
mesh_terms: D000818:Animals; D002169:Campylobacter Infections / Q000453:epidemiology / Q000382:microbiology* / Q000662:veterinary*; D016123:Campylobacter jejuni / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D002645:Chickens; D002681:China / Q000453:epidemiology; D016000:Cluster Analysis; D005516:Food Microbiology; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D017720:Molecular Epidemiology; D058885:Multilocus Sequence Typing