title: Update in Aphasia Research.
abstract: The sequelae of post-stroke aphasia are considerable, with implications at the societal and personal levels. An understanding of the mechanisms of recovery of cognitive and language processes after stroke and the factors associated with increased risk of post-stroke language and cognitive deficits is vital in providing optimal care of individuals with aphasia and in counseling to their families and caregivers. Advances in neuroimaging facilitate the identification of dysfunctional or damaged brain tissue responsible for these cognitive/language deficits and contribute insights regarding the functional neuroanatomy of language. Evidence-based person-centered behavioral therapy remains the mainstay for rehabilitation of aphasia, although emerging evidence shows that neuromodulation is a promising adjunct to traditional therapy. These topics are discussed in this review, illustrating with recent studies from the Stroke Cognitive Outcomes and REcovery (SCORE) lab.
authors.affiliation: Department of Neurology, Department of Physical Medicine and Rehabilitation, and Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, 6th Floor, Johns Hopkins Outpatient Center, 601 North Caroline Street, Baltimore, MD, 21287-0910, USA, dtippet1@jhmi.edu.
authors.forename: Donna C
authors.initials: DC
authors.lastname: Tippett
mesh_terms: D000818:Animals; D001037:Aphasia / Q000209:etiology / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D001521:Behavior Therapy; D017028:Caregivers; D006801:Humans; D059906:Neuroimaging / Q000379:methods; D020521:Stroke / Q000150:complications* / Q000473:pathology; D016896:Treatment Outcome