title: FeCl3-Catalyzed Combinatorial Synthesis of Functionalized Spiro[Indolo-3,10'-indeno [1,2-b]quinolin]-trione Derivatives.
abstract: An efficient, inexpensive, environmentally friendly and high yield one-pot route to new spiro[indolo-3,10'-indeno [1,2-b]quinolin]-trione derivatives has been developed, involving three-component reaction of enaminones, N-substituted isatins and Indane-1,3-dione catalyzed by FeCl3. The approach to this spiro-heterocycle is noteworthy because it results in the formation of three new σ (two C-C and one C-N) bonds in a single operation, leading to the construction of novel spiro skeleton. This method works on a large scale in excellent yields.
authors.affiliation: Department of Chemistry, University of Calcutta, 92 APC Road, Kolkata-700009, India.
authors.forename: Animesh
authors.initials: A
authors.lastname: Mondal
authors.affiliation: Department of Chemistry, University of Calcutta, 92 APC Road, Kolkata-700009, India.
authors.forename: Chhanda
authors.initials: C
authors.lastname: Mukhopadhyay
mesh_terms: D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D002712:Chlorides; D005290:Ferric Compounds; D007211:Indoles; D013141:Spiro Compounds; C024555:ferric chloride
keywords: Lewis acid catalysis; environmentally friendly; ferric trichloride; isatins; multicomponent reactions; spirocyclic compounds