title: HGF Guides T Cells into the Heart.
abstract: Expression of distinct homing receptors guides adaptive immune cells to antigen-rich tissue. In this issue of Immunity, Komarowska et al. (2015) describe an autocrine loop that is initiated by cardiac-expressed hepatocyte growth factor to direct T cells into the heart during inflammation and cardiac transplant rejection.
authors.affiliation: Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.
authors.forename: Dennis
authors.initials: D
authors.lastname: Wolf
authors.affiliation: Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA.
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.affiliation: Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, La Jolla, CA 92037, USA. Electronic address: klaus@liai.org.
authors.forename: Klaus
authors.initials: K
authors.lastname: Ley
mesh_terms: D000818:Animals; D006084:Graft Rejection / Q000517:prevention & control*; D006321:Heart / Q000502:physiology*; D016027:Heart Transplantation; D017228:Hepatocyte Growth Factor / Q000378:metabolism*; D006801:Humans; D019859:Proto-Oncogene Proteins c-met / Q000378:metabolism*; D013601:T-Lymphocytes / Q000502:physiology*
chemical_list: D017228:Hepatocyte Growth Factor; D019859:Proto-Oncogene Proteins c-met