title: Stereoselective chlorothiolation of artemisinin-derived C-10 oxa terminal alkynes.
abstract: A mild and efficient strategy is explored on the highly sensitive artemisinin-derived C-10 oxa terminal alkynes. Several novel artemisinin-derived (E)-2-chloroalkenyl sulfides (20) have been synthesized by using this protocol to study their anticancer activities.
authors.affiliation: Natural Products Chemistry Division, CSIR-North East Institute of Science and Technology, Jorhat, 785006, Assam, India.
authors.forename: Naresh
authors.initials: N
authors.lastname: Surineni
authors.affiliation: Natural Products Chemistry Division, CSIR-North East Institute of Science and Technology, Jorhat, 785006, Assam, India.
authors.forename: Pori
authors.initials: P
authors.lastname: Buragohain
authors.affiliation: Natural Products Chemistry Division, CSIR-North East Institute of Science and Technology, Jorhat, 785006, Assam, India. ncbarua2000@yahoo.co.in.
authors.forename: Nabin C
authors.initials: NC
authors.lastname: Barua
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry; D037621:Artemisinins / Q000737:chemistry*; D002240:Carbohydrate Sequence; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D037621:Artemisinins; C031327:artemisinin
keywords: Alkynes; Artemisinin; Chlorothiolation; Vinyl sulfides