title: Long-term outcomes following functional endoscopic sinus surgery in Samter's triad.
abstract: OBJECTIVE
  This study aimed to assess the long-term outcome of functional endoscopic sinus surgery for Samter's triad patients using an objective visual analogue scale and nasal endoscopy.
  
  
  METHODS
  Using a retrospective database, 33 Samter's triad patients who underwent functional endoscopic sinus surgery were evaluated pre- and post-operatively between 1987 and 2007 in Hospital of La Chaux-de-Fonds, Switzerland.
  
  
  RESULTS
  A total of 33 patients participated in the study, and the mean follow-up period was 11.6 years (range 1.2-20 years). Patients were divided into two groups based on visual analogue scale scores of the five parameters with the greatest difference in intensity of symptoms between the beginning and end of follow up. Group 1 included patients with a mean visual analogue scale score of 6 and below at the end of follow up and group 2 included patients with a mean visual analogue scale score of more than 6. The only statistically significant difference noted between the two groups was the endonasal findings: stage III-IV polyposis was present in 1 out of 24 patients (4 per cent) in group 1 and in 5 out of 9 patients (56 per cent) in group 2.
  
  
  CONCLUSIONS
  The results of our study indicate that functional endoscopic sinus surgery helps stabilise disease progression. Stage III-IV polyposis had a significant adverse effect on long-term outcome.
authors.affiliation: Otorhinolaryngology Service,Department of ENT,Head and Neck Surgery,Lausanne University Medical Centre (CHUV),Switzerland.
authors.forename: F
authors.initials: F
authors.lastname: Olivier
authors.affiliation: Otorhinolaryngology Service,Department of ENT,Head and Neck Surgery,Lausanne University Medical Centre (CHUV),Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: George
authors.affiliation: Otorhinolaryngology Service,Head and Neck Surgery,Hospital of La Chaux-de-Fonds,Switzerland.
authors.forename: D
authors.initials: D
authors.lastname: Leuba
authors.affiliation: Otorhinolaryngology Service,Department of ENT,Head and Neck Surgery,Lausanne University Medical Centre (CHUV),Switzerland.
authors.forename: P
authors.initials: P
authors.lastname: Monnier
authors.affiliation: Otorhinolaryngology Service,Head and Neck Surgery,Hospital of La Chaux-de-Fonds,Switzerland.
authors.forename: J P
authors.initials: JP
authors.lastname: Friedrich
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D001241:Aspirin / Q000009:adverse effects; D001249:Asthma / Q000150:complications* / Q000503:physiopathology; D004342:Drug Hypersensitivity / Q000150:complications* / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D005544:Forecasting; D006801:Humans; D008297:Male; D009298:Nasal Polyps / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D057605:Natural Orifice Endoscopic Surgery / Q000379:methods*; D009666:Nose; D013517:Otorhinolaryngologic Surgical Procedures / Q000379:methods*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis* / Q000503:physiopathology; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin
keywords: Aspirin Triad Disease; Endoscopic Surgical Procedure; Nasal Polyps; Treatment Outcome