title: Comparison of Serum Vitamin D Levels Among Patients With Chronic Kidney Disease, Patients in Dialysis, and Renal Transplant Patients.
abstract: OBJECTIVE
  Vitamin D is a hormone with a variety of functions, and its deficiency and insufficiency are commonly seen both in the general population and in patients with chronic renal disease. The aim of this study was to compare vitamin D levels in patients with chronic renal disease who are on hemodialysis, peritoneal dialysis, or no renal replacement therapy and patients who underwent renal transplantation.
  
  
  METHODS
  A total of 169 patients who had not used vitamin D for ≥ 1 year and who had no diabetes mellitus or proteinuria were included in the study. These included: 40 patients with renal transplantation, 40 patients on hemodialysis, 49 patients on peritoneal dialysis, and 40 patients with chronic renal failure stage 1, 2, 3, or 4. 25-Hydroxy vitamin D levels were evaluated in the sera of the patients.
  
  
  RESULTS
  25-Hydroxy vitamin D levels in patients with renal transplantation and in predialysis patients were 12.74 ± 10.24 ng/mL and 11.16 ± 12.25 ng/mL, respectively. The levels were 7.77 ± 6.71 ng/mL and 5.96 ± 4.87 ng/mL in patients on hemodialysis and peritoneal dialysis, respectively.
  
  
  CONCLUSIONS
  Vitamin D levels are lower in patients on hemodialysis and peritoneal dialysis compared with the patients with renal transplantation for a variety of reasons. In this study, objective results were obtained supporting the administration of vitamin D supplements without glomerular filtration rate measurement in all patient groups with the diagnosis of chronic renal failure in accordance with the guidelines.
authors.affiliation: Department of Nephrology, Faculty of Medicine, Ataturk University, Erzurum, Turkey. Electronic address: dr25erdem@gmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Çankaya
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: Y
authors.initials: Y
authors.lastname: Bilen
authors.affiliation: Department of Nephrology, Faculty of Medicine, Mevlana University, Konya, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Keleş
authors.affiliation: Department of Nephrology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Uyanık
authors.affiliation: Mengücek Veterans Education and Research Hospital Endocrinology Clinic, Erzincan University, Erzincan, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Akbaş
authors.affiliation: Department of Endocrinology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Güngör
authors.affiliation: Department of General Surgery, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: Ş
authors.initials: Ş
authors.lastname: Arslan
authors.affiliation: Department of General Surgery, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Aydınlı
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000453:epidemiology* / Q000209:etiology
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D