title: Quality of Life Among Breast Cancer Survivors 2 Years After Diagnosis: The Relationship With Adverse Childhood Events and Posttraumatic Growth.
abstract: BACKGROUND
  Quality of life (QoL) is an important patient outcome in oncology. Many breast cancer survivors report difficulties with QoL. Adverse childhood events (ACEs) and posttraumatic growth (PTG) may influence QoL in breast cancer survivors after diagnosis.
  
  
  OBJECTIVE
  The aim of this study was to determine the association of QoL with ACEs and PTG among breast cancer survivors 2 years after diagnosis.
  
  
  METHODS
  This was a cross-sectional study, conducted on 93 Chinese breast cancer survivors diagnosed at least 2 years prior to the study. Measures included a self-reported demographic questionnaire, the Adverse Childhood Experiences questionnaires, the Posttraumatic Growth Inventory, and the Functional Assessment of Cancer Therapy-Breast Cancer QoL questionnaire.
  
  
  RESULTS
  Among the 93 participants, more than one-third (34.4%) experienced childhood adversity. We found a negative relationship between ACEs and QoL and a positive relationship between PTG and QoL.
  
  
  CONCLUSIONS
  The findings suggest that childhood adversity and PTG are important predictors of QoL among breast cancer survivors at least 2 years after diagnosis. Women who had experienced ACEs had poorer health-related QoL than did those who did not. Individuals who experienced PTG following a cancer diagnosis also reported better QoL than did those who did not.
  
  
  CONCLUSIONS
  A better understanding of how ACE and PTG contribute to breast cancer survivors' QoL will help in tailoring and therefore enhancing the efficacy of interventions aimed at improving QoL.
authors.affiliation: Author Affiliations: School of Nursing, Shandong University, Jinan, Shandong, People's Republic of China.
authors.forename: Xue
authors.initials: X
authors.lastname: Jiao-Mei
authors.forename: Gao
authors.initials: G
authors.lastname: Wen
authors.forename: Cao
authors.initials: C
authors.lastname: Feng-Lin
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000069586:Adult Survivors of Child Adverse Events / Q000523:psychology* / Q000706:statistics & numerical data; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000175:diagnosis / Q000523:psychology*; D002681:China; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D011788:Quality of Life; D011795:Surveys and Questionnaires; D017741:Survivors / Q000523:psychology* / Q000706:statistics & numerical data; D013997:Time Factors