title: [Pemphigoid diseases. Autoimmune diseases in the elderly].
abstract: BACKGROUND
  The incidence and thereby also the relevance of pemphigoid diseases have significantly increased in elderly patients.
  
  
  METHODS
  The clinical features, diagnostic workup, and therapy of pemphigoid diseases based on the recently published German guidelines and expert opinions are described.
  
  
  RESULTS
  The diagnosis is based on medical history, clinical manifestations, histopathology, and autoimmune serology. Treatment options depend on the diagnosis and disease severity. Both local and systemic immunosuppressive or immunomodulatory strategies have been proven to be effective.
  
  
  CONCLUSIONS
  Chronic, itchy, inflammatory skin disorders in elderly patients are generally suspicious for pemphigoid diseases. The prognosis is usually good. For decisions about (local or systemic) immunosuppressive therapy, gerontological aspects should be taken into consideration.
authors.affiliation: Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität, Frauenlobstr. 9-11, 80337, München, Deutschland.
authors.forename: O N
authors.initials: ON
authors.lastname: Horváth
authors.forename: J
authors.initials: J
authors.lastname: Jankásková
authors.forename: A
authors.initials: A
authors.lastname: Walker
authors.forename: M
authors.initials: M
authors.lastname: Sárdy
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003880:Dermatology / Q000592:standards*; D005260:Female; D015577:Geriatric Assessment / Q000379:methods*; D005853:Geriatrics / Q000592:standards; D005858:Germany; D006801:Humans; D007155:Immunologic Factors / Q000592:standards / Q000627:therapeutic use*; D007166:Immunosuppressive Agents / Q000592:standards / Q000627:therapeutic use*; D008297:Male; D010391:Pemphigoid, Bullous / Q000175:diagnosis* / Q000628:therapy*; D017410:Practice Guidelines as Topic
chemical_list: D007155:Immunologic Factors; D007166:Immunosuppressive Agents