title: Breast cancer screening controversies: who, when, why, and how?
abstract: Mammographic screening is effective in reducing mortality from breast cancer. The issue is not whether mammography is effective, but whether the false positive rate and false negative rates can be reduced. This review will discuss controversies including the reduction in breast cancer mortality, overdiagnosis, the ideal screening candidate, and the optimal imaging modality for breast cancer screening. The article will compare and contrast screening mammography, tomosynthesis, whole-breast screening ultrasound, magnetic resonance imaging, and molecular breast imaging. Though supplemental imaging modalities are being utilized to improve breast cancer diagnosis, mammography still remains the gold standard for breast cancer screening.
authors.affiliation: Penn State Milton S. Hershey Medical Center, Penn State Hershey Breast Imaging, Department of Radiology, EC 008, 30 Hope Drive, Suite 1800, Hershey, PA, 17033-0859. Electronic address: achetlen@hmc.psu.edu.
authors.forename: Alison
authors.initials: A
authors.lastname: Chetlen
authors.affiliation: Penn State Milton S. Hershey Medical Center, Penn State Hershey Breast Imaging, Department of Radiology, EC 008, 30 Hope Drive, Suite 1800, Hershey, PA, 17033-0859. Electronic address: jmack@hmc.psu.edu.
authors.forename: Julie
authors.initials: J
authors.lastname: Mack
authors.affiliation: Penn State Milton S. Hershey Medical Center, Penn State Hershey Breast Imaging, Department of Radiology, EC 008, 30 Hope Drive, Suite 1800, Hershey, PA, 17033-0859. Electronic address: tchan@hmc.psu.edu.
authors.forename: Tiffany
authors.initials: T
authors.lastname: Chan
mesh_terms: D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis*; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008327:Mammography / Q000379:methods*; D018570:Risk Assessment; D016217:Ultrasonography, Mammary / Q000379:methods*
keywords: Automated whole-breast ultrasound; Breast cancer screening; Magnetic resonance imaging; Mammography; Tomosynthesis