title: Formal Total Synthesis of Echinopines A and B via Cr(0)-Promoted [6π + 2π] Cycloaddition.
abstract: A concise formal synthesis of echinopines A and B is reported. The key [5.5.7] tricyclic intermediate, which has been previously used for the synthesis of echinopine A and B, was assembled using Cr(0)-promoted photochemical [6π + 2π] cycloaddition followed by a radical cyclization step.
authors.affiliation: Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States.
authors.forename: Saptarshi
authors.initials: S
authors.lastname: De
authors.affiliation: Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States.
authors.forename: Shilpi
authors.initials: S
authors.lastname: Misra
authors.affiliation: Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States.
authors.forename: James H
authors.initials: JH
authors.lastname: Rigby
mesh_terms: D003500:Cyclization; D061565:Cycloaddition Reaction; D031182:Echinops Plant / Q000737:chemistry; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D012717:Sesquiterpenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D012717:Sesquiterpenes; C527602:echinopine A; C527604:echinopine B