title: [Effect of Ca(OH)2 pre-treated on remineralization of the demineralized dentin induced by polyamidoamine dendrime].
abstract: OBJECTIVE
  To evaluate the remineralization effect of Ca(OH)2 pre-treated with carboxylmodified polyamidoamine dendrimer (PAMAM) on demineralized dentin.
  
  
  METHODS
  Thirty-two demineralized dentin models were divided into four groups randomly as follows: control group with no treatment, Ca(OH)2 group pretreated with Ca(OH)2 solution, PAMAM group processed with carboxyl-modified PAMAM, and PAMAM+Ca(OH)2 group processed with carboxyl-modified PAMAM and pretreated with Ca(OH)2 solution. All samples were immersed in artificial saliva for two weeks. The remineralization effects of dentin discs were evaluated by scanning electron microscope (SEM), energy dispersive spectrometer (EDS) and X-ray diffraction (XRD).
  
  
  RESULTS
  Observed by the SEM, it was showed that in PAMAM+Ca(OH)2 group almost all the dentinal tubules were occluded by the minerals, however this was not found in other groups. The minerals proved were hydroxyapatite through EDS and XRD tests.
  
  
  CONCLUSIONS
  There was potential superiority of the carboxyl-modified PAMAM with Ca(OH)2 solution in promoting the remineralization of initial dentin lesions.
authors.affiliation: Department of Endodontics, College of Stomatology Guangxi Medical University, Nanning 530021, China; Email: 759805241@qq.com.
authors.forename: Fangfang
authors.initials: F
authors.lastname: Xie
authors.affiliation: Department of Endodontics, College of Stomatology Guangxi Medical University, Nanning 530021, China.
authors.forename: Qiurong
authors.initials: Q
authors.lastname: Li
authors.affiliation: Department of Endodontics, College of Stomatology Guangxi Medical University, Nanning 530021, China.
authors.forename: Xiaolang
authors.initials: X
authors.lastname: Wei
authors.affiliation: Department of Endodontics, College of Stomatology Guangxi Medical University, Nanning 530021, China.
authors.forename: Tong
authors.initials: T
authors.lastname: Zhou
mesh_terms: D002113:Calcification, Physiologic / Q000187:drug effects*; D002126:Calcium Hydroxide / Q000494:pharmacology*; D003804:Dentin / Q000187:drug effects* / Q000502:physiology; D017886:Durapatite; D006801:Humans; D008855:Microscopy, Electron, Scanning; D011073:Polyamines / Q000494:pharmacology*; D011897:Random Allocation; D012464:Saliva, Artificial; D014961:X-Ray Diffraction
chemical_list: C531249:Poly(amidoamine); D011073:Polyamines; D012464:Saliva, Artificial; D017886:Durapatite; D002126:Calcium Hydroxide