title: A visual physiological temperature sensor developed with gelatin-stabilized luminescent silver nanoclusters.
abstract: A visual physiological temperature sensor was successfully developed with newly hydrothermally prepared fluorescent silver nanoclusters (AgNCs) at room temperature using gelatin as the protective and reducing agent. The as-prepared gelatin-stabilized AgNCs was water-soluble, uniform and exhibited a narrow distribution with an average size of 1.16 nm, showing a maximum emission band at 552 nm (2.45 eV) when excited at 445 nm (2.79 eV). The large Stokes shift of 110 nm of the gelatin-stabilized AgNCs makes it actually applicable with very low background and light scattering interferences. It was found that the as-prepared gelatin-stabilized AgNCs is temperature-sensitive over the range from 5°C to 45°C, and thus a visual physiological temperature sensor could be developed with the gelatin-AgNCs as under the irradiation of visible light.
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Lan
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Zou
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China.
authors.forename: Zexi
authors.initials: Z
authors.lastname: Liu
authors.affiliation: College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
authors.forename: Mingxuan
authors.initials: M
authors.lastname: Gao
authors.affiliation: College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
authors.forename: Binbin
authors.initials: B
authors.lastname: Chen
authors.affiliation: College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
authors.forename: Yuanfang
authors.initials: Y
authors.lastname: Li
authors.affiliation: Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715, China; College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China. Electronic address: chengzhi@swu.edu.cn.
authors.forename: Chengzhi
authors.initials: C
authors.lastname: Huang
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D005780:Gelatin / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D049449:Luminescence; D049329:Nanostructures / Q000737:chemistry*; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D013696:Temperature
chemical_list: D012834:Silver; D005780:Gelatin
keywords: Ag nanoclusters; Fluorescence; Gelatin; Temperature sensor