title: Nickel-catalyzed Suzuki-Miyaura type cross-coupling reactions of (2,2-difluorovinyl)benzene derivatives with arylboronic acids.
abstract: An unprecedented highly stereoselective example of nickel-catalyzed Suzuki-Miyaura type cross-coupling reactions of (2,2-difluorovinyl)benzene derivatives with arylboronic acids was developed. The reaction proceeded efficiently in the presence of 5 mol% NiCl2(PCy3)2 and K3PO4, affording the Z-fluorostyrene derivatives in good to high yields with excellent regioselectivity.
authors.affiliation: Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology (ECUST), Shanghai 200237, China. scao@ecust.edu.cn wujj@sit.edu.cn.
authors.forename: Yang
authors.initials: Y
authors.lastname: Xiong
authors.forename: Tao
authors.initials: T
authors.lastname: Huang
authors.forename: Xinfei
authors.initials: X
authors.lastname: Ji
authors.forename: Jingjing
authors.initials: J
authors.lastname: Wu
authors.forename: Song
authors.initials: S
authors.lastname: Cao
mesh_terms: D001555:Benzene Derivatives / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D008956:Models, Chemical; D009532:Nickel / Q000737:chemistry*; D013267:Stilbenes / Q000737:chemistry
chemical_list: D001555:Benzene Derivatives; D001897:Boronic Acids; D013267:Stilbenes; D009532:Nickel; C058728:fosbretabulin