title: High-Flow Nasal Cannula Therapy for Obstructive Sleep Apnea in Children.
abstract: BACKGROUND
  Over the last decade, high-flow nasal cannula (HFNC) therapy has become an increasingly important and popular mode of noninvasive respiratory support. HFNC facilitates delivery of humidified and heated oxygen at a high flow rate and generates positive airway pressure.
  
  
  METHODS
  We present five cases of children with OSA without adenotonsillar hypertrophy who were treated with HFNC.
  
  
  RESULTS
  We demonstrated a statistically significant improvement in apnea-hypopnea index and nadir oxygen saturation in this small cohort.
  
  
  CONCLUSIONS
  We present our successful experience of treating severe OSA with HFNC in the home setting. Further randomized controlled trials are needed to determine whether HFNC could be considered as an established alternative for CPAP in OSA in children.
authors.affiliation: Pediatric Pulmonary Unit, Shaare Zedek Medical Center, affiliated with the Hebrew University School of Medicine, Jerusalem, Israel.
authors.forename: Leon
authors.initials: L
authors.lastname: Joseph
authors.affiliation: Pediatric Pulmonary Unit, Shaare Zedek Medical Center, affiliated with the Hebrew University School of Medicine, Jerusalem, Israel.
authors.forename: Shmuel
authors.initials: S
authors.lastname: Goldberg
authors.affiliation: Pediatric Pulmonary Unit, Shaare Zedek Medical Center, affiliated with the Hebrew University School of Medicine, Jerusalem, Israel.
authors.forename: Michal
authors.initials: M
authors.lastname: Shitrit
authors.affiliation: Pediatric Pulmonary Unit, Shaare Zedek Medical Center, affiliated with the Hebrew University School of Medicine, Jerusalem, Israel.
authors.forename: Elie
authors.initials: E
authors.lastname: Picard
mesh_terms: D000293:Adolescent; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010102:Oxygen Inhalation Therapy / Q000379:methods*; D020181:Sleep Apnea, Obstructive / Q000628:therapy*
keywords: high-flow therapy; home care; obstructive sleep apnea; pediatrics