title: Detection of Circovirus in Foxes with Meningoencephalitis, United Kingdom, 2009-2013.
abstract: A fox circovirus was identified in serum samples from foxes with unexplained neurologic signs by using viral metagenomics. Fox circovirus nucleic acid was localized in histological lesions of the cerebrum by in situ hybridization. Viruses from the family Circoviridae may have neurologic tropism more commonly than previously anticipated.
authors.forename: Steve
authors.initials: S
authors.lastname: Bexton
authors.forename: Lidewij C
authors.initials: LC
authors.lastname: Wiersma
authors.forename: Sarah
authors.initials: S
authors.lastname: Getu
authors.forename: Peter R
authors.initials: PR
authors.lastname: van Run
authors.forename: Georges M G M
authors.initials: GM
authors.lastname: Verjans
authors.forename: Debby
authors.initials: D
authors.lastname: Schipper
authors.forename: Claudia M E
authors.initials: CM
authors.lastname: Schapendonk
authors.forename: Rogier
authors.initials: R
authors.lastname: Bodewes
authors.forename: Lucy
authors.initials: L
authors.lastname: Oldroyd
authors.forename: Bart L
authors.initials: BL
authors.lastname: Haagmans
authors.forename: Marion M P
authors.initials: MM
authors.lastname: Koopmans
authors.forename: Saskia L
authors.initials: SL
authors.lastname: Smits
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology / Q000821:virology; D018173:Circoviridae Infections / Q000175:diagnosis / Q000662:veterinary* / Q000821:virology; D017925:Circovirus / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D005589:Foxes / Q000821:virology*; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis / Q000662:veterinary* / Q000821:virology; D025202:Molecular Diagnostic Techniques; D060888:Real-Time Polymerase Chain Reaction; D006113:United Kingdom
keywords: United Kingdom; brain; cerebrospinal fluid; circovirus; cyclovirus; encephalitis; foxes; meningoencephalitis; neurologic disease; random amplification; serum; viruses