title: Alterations in acute myeloid leukaemia bone marrow stromal cell exosome content coincide with gains in tyrosine kinase inhibitor resistance.
authors.affiliation: Pape Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Shelton
authors.initials: S
authors.lastname: Viola
authors.affiliation: Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Elie
authors.initials: E
authors.lastname: Traer
authors.affiliation: Pape Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Jianya
authors.initials: J
authors.lastname: Huan
authors.affiliation: Pape Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Noah I
authors.initials: NI
authors.lastname: Hornick
authors.affiliation: Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.|Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Tyner
authors.affiliation: Department of Molecular and Cellular Genetics, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Anupriya
authors.initials: A
authors.lastname: Agarwal
authors.affiliation: Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.|Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR, USA.|Department of Pathology, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Marc
authors.initials: M
authors.lastname: Loriaux
authors.affiliation: Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, OR, USA.
authors.forename: Brian
authors.initials: B
authors.lastname: Johnstone
authors.affiliation: Pape Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR, USA. kurrepe@ohsu.edu.|Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. kurrepe@ohsu.edu.|Cell, Developmental & Cancer Biology, Oregon Health & Science University, Portland, OR, USA. kurrepe@ohsu.edu.
authors.forename: Peter
authors.initials: P
authors.lastname: Kurre
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002648:Child; D019008:Drug Resistance, Neoplasm; D055354:Exosomes / Q000473:pathology*; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000473:pathology*; D008297:Male; D059630:Mesenchymal Stem Cells / Q000473:pathology*; D008875:Middle Aged; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use*; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents; D047428:Protein Kinase Inhibitors; D011505:Protein-Tyrosine Kinases
keywords: acute myeloid leukaemia; chemo-resistance; exosomes; microRNA; stroma