title: Unusual Case of Cerebral Venous Thrombosis in Patient with Crohn's Disease.
abstract: The development of cerebral venous thrombosis (CVT) as a secondary complication of Crohn's disease (CD) seems to be rare, but it is generally accepted that the disease activity of CD contributes to the establishment of a hypercoagulable state. Here, we describe a case of CVT that developed outside the active phase of CD. A 17-year-old male visited the emergency room because of a sudden onset of right-sided weakness and right-sided hypesthesia. He had been diagnosed with CD 1 year before and was on a maintenance regimen of mesalazine and azathioprine. He did not exhibit any symptoms indicating a CD flare-up (bloody stools, abdominal pain, complications, or weight loss). A brain MRI scan revealed an acute infarction of the left frontal cortex and a cortical subarachnoid hemorrhage. Additionally, a magnetic resonance venography revealed a segmental filling defect in the superior sagittal sinus and also the non-visualizability of some bilateral cortical veins. The characteristics of the present case suggest that the risk of CVT is most likely related to CD per se rather than disease activity associated with CD.
authors.affiliation: Neurology, Chungbuk National University Hospital, Cheongju, Korea.
authors.forename: Inha
authors.initials: I
authors.lastname: Kim
authors.affiliation: Neurology, Chungbuk National University Hospital, Cheongju, Korea.
authors.forename: Kyung-Hyun
authors.initials: KH
authors.lastname: Min
authors.affiliation: Neurology, Chungbuk National University Hospital, Cheongju, Korea.
authors.forename: Minju
authors.initials: M
authors.lastname: Yeo
authors.affiliation: Department of Neurology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
authors.forename: Ji Seon
authors.initials: JS
authors.lastname: Kim
authors.affiliation: Department of Neurology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
authors.forename: Sung Hyun
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Neurology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
authors.forename: Sang Soo
authors.initials: SS
authors.lastname: Lee
authors.affiliation: Department of Laboratory Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
authors.forename: Kyeong Seob
authors.initials: KS
authors.lastname: Shin
authors.affiliation: Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
authors.forename: Sei Jin
authors.initials: SJ
authors.lastname: Youn
authors.affiliation: Department of Neurology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
authors.forename: Dong Ick
authors.initials: DI
authors.lastname: Shin
keywords: Cerebral venous thrombosis; Crohn's disease; Disease activity