title: Multicenter evaluation of BD Veritor System and RSV K-SeT for rapid detection of respiratory syncytial virus in a diagnostic laboratory setting.
abstract: The recently introduced BD Veritor System RSV laboratory kit (Becton Dickinson, Sparks, MD, USA) with automatic reading was evaluated and compared with the RSV K-SeT (Coris BioConcept, Gembloux, Belgium) for the detection of respiratory syncytial virus (RSV) using 248 nasopharyngeal aspirates of children younger than 6 years old with respiratory tract infection. Compared to reverse transcriptase polymerase chain reaction as gold standard, both tests had an identical sensitivity of 78.1% and a specificity of 96.8% and 95.8% for the BD Veritor System and RSV K-SeT, respectively. Both antigen tests can be used to reliably confirm RSV in young children. However, a negative result does not definitively exclude the presence of RSV.
authors.affiliation: Clinical Laboratory of Microbiology, OLVZ Aalst, Moorselbaan 164, 9300 Aalst, Belgium.
authors.forename: Stijn
authors.initials: S
authors.lastname: Jonckheere
authors.affiliation: Clinical Laboratory of Microbiology, AZ Sint-Lucas Gent, Groenebriel 1, 9000 Gent, Belgium.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Verfaillie
authors.affiliation: Clinical Laboratory of Microbiology, OLVZ Aalst, Moorselbaan 164, 9300 Aalst, Belgium.
authors.forename: An
authors.initials: A
authors.lastname: Boel
authors.affiliation: Clinical Laboratory of Microbiology, OLVZ Aalst, Moorselbaan 164, 9300 Aalst, Belgium.
authors.forename: Kristien
authors.initials: K
authors.lastname: Van Vaerenbergh
authors.affiliation: Clinical Laboratory of Microbiology, AZ Sint-Lucas Gent, Groenebriel 1, 9000 Gent, Belgium.
authors.forename: Elke
authors.initials: E
authors.lastname: Vanlaere
authors.affiliation: Clinical Laboratory of Microbiology, OLVZ Aalst, Moorselbaan 164, 9300 Aalst, Belgium.
authors.forename: Anne
authors.initials: A
authors.lastname: Vankeerberghen
authors.affiliation: Clinical Laboratory of Microbiology, OLVZ Aalst, Moorselbaan 164, 9300 Aalst, Belgium. Electronic address: Hans.De.Beenhouwer@olvz-aalst.be.
authors.forename: Hans
authors.initials: H
authors.lastname: De Beenhouwer
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D019411:Clinical Laboratory Techniques / Q000379:methods*; D002986:Clinical Trials as Topic; D003955:Diagnostic Tests, Routine / Q000379:methods*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009305:Nasopharynx / Q000821:virology; D011237:Predictive Value of Tests; D011446:Prospective Studies; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis*; D012136:Respiratory Syncytial Viruses / Q000302:isolation & purification*; D012680:Sensitivity and Specificity
chemical_list: D000956:Antigens, Viral
keywords: Antigen test; BD Veritor System; RSV; RSV K-SeT; RSV Respi-Strip