title: Cladophialophora bantiana as an Emerging Pathogen in Animals: Case Report of Equine Endometritis and Review of the Literature.
abstract: We present an unusual equine endometritis case associated with Cladophialophora bantiana in a 15-year-old mare. The mare displayed infertility and uterine fluid accumulation with numerous black, hairy granules. Microscopically, the fluid revealed numerous septate, dark fungal hyphae and conidia in chains. Culture yielded C. bantiana (CBS 138271); the species was confirmed by internal transcribed spacer (ITS) sequencing. Treatment was unsuccessful. C. bantiana causes cerebral phaeohyphomycosis in humans, while animal cases are rare. Animal cases are reviewed.
authors.affiliation: Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland merja.rantala@helsinki.fi.
authors.forename: Merja
authors.initials: M
authors.lastname: Rantala
authors.affiliation: Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Saarentaus, Finland.
authors.forename: Stella
authors.initials: S
authors.lastname: Attia
authors.affiliation: Mycology Unit, Helsinki University Hospital Laboratory HUSLAB, Helsinki, Finland.
authors.forename: Pirkko
authors.initials: P
authors.lastname: Koukila-Kähkölä
authors.affiliation: CBS Fungal Biodiversity Centre, Institute of the Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands.
authors.forename: Sybren
authors.initials: S
authors.lastname: de Hoog
authors.affiliation: Pathology Research Unit, Research and Laboratory Department, Finnish Food Safety Authority Evira, Helsinki, Finland.
authors.forename: Marjukka
authors.initials: M
authors.lastname: Anttila
authors.affiliation: Department of Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Saarentaus, Finland.
authors.forename: Terttu
authors.initials: T
authors.lastname: Katila
mesh_terms: D000818:Animals; D001203:Ascomycota / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D016000:Cluster Analysis; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D021903:DNA, Ribosomal Spacer / Q000737:chemistry / Q000235:genetics; D004716:Endometritis / Q000382:microbiology / Q000473:pathology* / Q000662:veterinary*; D005122:Exudates and Transudates / Q000382:microbiology; D005260:Female; D006734:Horse Diseases / Q000382:microbiology* / Q000473:pathology*; D006736:Horses; D008828:Microbiological Techniques; D008853:Microscopy; D008969:Molecular Sequence Data; D009181:Mycoses / Q000382:microbiology / Q000473:pathology* / Q000662:veterinary*; D010802:Phylogeny; D011247:Pregnancy; D017422:Sequence Analysis, DNA
chemical_list: D004271:DNA, Fungal; D021903:DNA, Ribosomal Spacer