title: [Suicide attempt by means of phenobarbital overdose. Effective treatment with continuous veno-venous hemodialysis].
abstract: A 68-year-old woman tried to commit suicide using phenobarbital, which was initially prescribed for her dog that suffered from seizures. At admission she was unconscious and ventilated. Five days of intensive care therapy did not improve her state of consciousness. Subsequent continuous veno-venous hemodialysis accelerated the elimination of phenobarbital compared to endogenous elimination by a factor of five. The patient survived without sequelae. Detailed history taking and well-timed indication for dialysis were crucial.
authors.affiliation: Medizinische Klinik I, Klinikum Herford, Schwarzenmoorstraße 70, 32049, Herford, Deutschland. mmwruhe@gmail.com.
authors.forename: M
authors.initials: M
authors.lastname: Ruhe
authors.affiliation: Medizinische Klinik III, Klinikum Herford, Schwarzenmoorstraße 70, 32049, Herford, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Grautoff
authors.affiliation: Medizinische Klinik III, Klinikum Herford, Schwarzenmoorstraße 70, 32049, Herford, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Kähler
authors.affiliation: Medizinische Klinik I, Klinikum Herford, Schwarzenmoorstraße 70, 32049, Herford, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Pohle
mesh_terms: D000368:Aged; D000927:Anticonvulsants / Q000493:pharmacokinetics / Q000506:poisoning*; D005260:Female; D006440:Hemofiltration; D006801:Humans; D007362:Intensive Care Units; D008657:Metabolic Clearance Rate / Q000502:physiology; D010634:Phenobarbital / Q000493:pharmacokinetics / Q000506:poisoning*; D013406:Suicide, Attempted
chemical_list: D000927:Anticonvulsants; D010634:Phenobarbital
keywords: Anticonvulsants; Barbiturates; Coma; Electroencephalography; Veterinary drugs