title: [Influence of Comorbidity on Mortality and Morbidity in the Radical Cystectomy for Bladder Cancer].
abstract: Radical cystectomy (RC) with bilateral pelvic lymph node dissection constitutes the gold standard treatment for muscle-invasive and high-risk non-muscle-invasive urothelial carcinoma of the bladder refractory to instillation therapy. Although radical cystectomy is performed with curative intent, the overall 5-year survival has been reported to be as low as 62% in the current literature. Various clinico-pathological parameters determine post-RC outcome, but besides these, the role of comorbidity has gained increasing attention and can be quantified with various comorbidity scores. We here review the most recent data on comorbidity scores and performance indices, which have been assessed in patients, undergoing RC and highlight their clinical implications.
authors.affiliation: Klinik und Poliklinik für Urologie der Universität Regensburg am Caritas-Krankenhaus St. Josef, Regensburg.
authors.forename: R
authors.initials: R
authors.lastname: Mayr
authors.affiliation: Abteilung für Urologie, Zentralkrankenhaus Bozen, Bozen.
authors.forename: A
authors.initials: A
authors.lastname: Pycha
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality* / Q000601:surgery*; D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000601:surgery*; D002295:Carcinoma, Transitional Cell / Q000401:mortality* / Q000601:surgery*; D015897:Comorbidity; D015653:Cystectomy; D005260:Female; D005858:Germany; D006304:Health Status; D006801:Humans; D008297:Male; D012307:Risk Factors; D016019:Survival Analysis; D001749:Urinary Bladder Neoplasms / Q000401:mortality* / Q000601:surgery*