title: Pulp Revascularization on Permanent Teeth with Open Apices in a Middle-aged Patient.
abstract: Pulp revascularization is a promising procedure for the treatment of adolescents' immature permanent teeth with necrotic pulp and/or apical periodontitis. However, the ability to successfully perform pulp revascularization in a middle-aged patient remains unclear. A 39-year-old woman was referred for treatment of teeth #20 and #29 with necrotic pulp, extensive periapical radiolucencies, and incomplete apices. Pulp revascularization procedures were attempted, including root canal debridement, triple antibiotic paste medication, and platelet-rich plasma transplantation to act as a scaffold. Periapical radiographic and cone-beam computed tomographic examinations were used to review the changes in the apical lesions and root apex configuration. The patient remained asymptomatic throughout the 30-month follow-up. Periapical radiographic examination revealed no change in the apical lesions of either tooth at 8 months. The periapical radiolucency disappeared on tooth #20 and significantly decreased on tooth #29 by the 30-month follow-up, findings that were also confirmed by cone-beam computed tomographic imaging. No evidence of root lengthening or thickening was observed. Successful revascularization was achieved in a middle-aged patient's teeth.
authors.affiliation: Paediatric Dentistry, School and Hospital of Stomatology, Peking University, Beijing, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
authors.affiliation: VIP Dental Service and Geriatric Dentistry, School and Hospital of Stomatology, Peking University, Beijing, China.
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Zhu
authors.affiliation: Shenzhen Institute of Research and Innovation, The University of Hong Kong, Hong Kong, China; Comprehensive Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China. Electronic address: zhangcf@hku.hk.
authors.forename: Chengfei
authors.initials: C
authors.lastname: Zhang
mesh_terms: D000328:Adult; D003790:Dental Pulp Necrosis / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D006801:Humans; D018919:Neovascularization, Physiologic; D010485:Periapical Periodontitis / Q000000981:diagnostic imaging / Q000628:therapy*; D011861:Radiography, Dental; D012390:Root Canal Therapy / Q000379:methods*; D019553:Tooth, Nonvital / Q000000981:diagnostic imaging / Q000628:therapy*
keywords: Apical periodontitis; middle-aged patient; pulp revascularization