title: Update on Testosterone Replacement Therapy in Hypogonadal Men.
abstract: Late-onset male hypogonadism has long been recognized as a treatable medical condition; however, misconceptions about the use of testosterone replacement therapy (TRT) have often led urologists away from its more mainstream use. This paper aims to bring the reader up-to-date on the current understanding of TRT, starting with when and who to treat. Various formulations of TRT, each with its own risks and benefits, are also detailed. Finally, a comprehensive analysis of the current literature's views into the various controversies of TRT including its impact on prostate health, sexual health, cardiovascular health, frailty, and mood is discussed.
authors.affiliation: McGill University, 9D-1210 Boulevard de Maisonneuve Ouest, Montreal, QC, H3A0A2, Canada, Kevin.Leung@mail.mcgill.ca.
authors.forename: Kevin Matthew Yen Bing
authors.initials: KM
authors.lastname: Leung
authors.forename: Khalid
authors.initials: K
authors.lastname: Alrabeeah
authors.forename: Serge
authors.initials: S
authors.lastname: Carrier
mesh_terms: D000375:Aging; D020249:Hormone Replacement Therapy; D006801:Humans; D007006:Hypogonadism / Q000188:drug therapy*; D008297:Male; D011471:Prostatic Neoplasms / Q000209:etiology; D012307:Risk Factors; D013739:Testosterone / Q000627:therapeutic use*
chemical_list: D013739:Testosterone