title: Proteomics for Early Diagnostics.
abstract: Advances in molecular biology over the past decade have helped to enhance understanding of the complex interplay between genetic, transcriptional, and translational alterations in human cancers. These molecular changes are the basis for an evolving field of high-throughput cancer discovery techniques using microscopic amounts of patient-based materials. In recent years, there has been an explosion in the development of new tools to analyze the proteome of cells, blood, and other body fluids. The information that is expected from such technologies may soon exert a dramatic change in the pace of cancer research and impact dramatically on the care of cancer patients.
authors.affiliation: Department of Oral and Maxillofacial Surgery, MGV KBH Dental College, Nashik, Maharashtra, India.
authors.forename: Shrikant B
authors.initials: SB
authors.lastname: Mali
mesh_terms: D002471:Cell Transformation, Neoplastic / Q000235:genetics; D055088:Early Detection of Cancer; D015972:Gene Expression Regulation, Neoplastic / Q000235:genetics; D006801:Humans; D008967:Molecular Biology / Q000379:methods*; D009363:Neoplasm Proteins / Q000032:analysis; D009369:Neoplasms / Q000175:diagnosis* / Q000235:genetics*; D011237:Predictive Value of Tests; D014176:Protein Biosynthesis / Q000235:genetics; D040901:Proteomics / Q000379:methods*; D014158:Transcription, Genetic / Q000235:genetics
chemical_list: D009363:Neoplasm Proteins