title: Surgical induced astigmatism correlated with corneal pachymetry and intraocular pressure: transconjunctival sutureless 23-gauge versus 20-gauge sutured vitrectomy in diabetes mellitus.
abstract: OBJECTIVE
  To determine the difference of surgical induced astigmatism between conventional 20-gauge sutured vitrectomy and 23-gauge transconjunctival sutureless vitrectomy, and the influence of corneal pachymetry and intraocular pressure (IOP) on surgical induced astigmatism in diabetic patients.
  
  
  METHODS
  This retrospective, consecutive case series consisted of 40 eyes of 38 diabetic subjects who underwent either 20-gauge or 23-gauge vitrectomy. The corneal curvature and thickness were measured with Scheimpflug imaging before surgery and 1wk; 1, 3mo after surgery. We compared the surgical induced astigmatism (SIA) on the true net power in 23-gauge group with that in 20-gauge group. We determined the correlation between corneal thickness change ratio, IOP and SIA measured by Pentacam.
  
  
  RESULTS
  The mean SIAs were 1.082±0.085 D (mean±SEM), 0.689±0.070 D and 0.459±0.063 D at postoperative 1wk; 1, 3mo respectively in diabetic subjects. The vitrectomy induced astigmatisms were declined significantly with time (F 2,36=33.629, P=0.000) postoperatively. The 23-gauge surgery group induced significantly less astigmatism than 20-gauge surgery group (F -1,37=11.046, P=0.020). Corneal thickness in diabetes elevated after surgery (F 3,78=10.532, P=0.000). The linear regression analysis at postoperatively 1wk went as: SIA=-4.519+4.931 change ratio (Port3) +0.026 IOP (R(2)=0.46, P=0.000), whereas the rate of corneal thickness change and IOP showed no correlation with the change of astigmatism at postoperatively 1 and 3mo.
  
  
  CONCLUSIONS
  There are significant serial changes in both 20-gauge and 23-gauge group in diabetic subjects. 23-gauge induce less astigmatism than 20-gauge and become stable more rapidly than 20-gauge. The elevation of corneal thickness and IOP was associated with increased astigmatim at the early postoperative stage both in 23-gauge and 20-gauge surgery group.
authors.affiliation: Tianjin Medical University Eye Hospital; Tianjin Medical University Eye Institute; The College of Optometry & Ophthalmology, Tianjin 300384, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Shao
authors.affiliation: Tianjin Medical University Eye Hospital; Tianjin Medical University Eye Institute; The College of Optometry & Ophthalmology, Tianjin 300384, China.
authors.forename: Li-Jie
authors.initials: LJ
authors.lastname: Dong
authors.affiliation: Tianjin Medical University Eye Hospital; Tianjin Medical University Eye Institute; The College of Optometry & Ophthalmology, Tianjin 300384, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Tianjin Medical University Eye Hospital; Tianjin Medical University Eye Institute; The College of Optometry & Ophthalmology, Tianjin 300384, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.affiliation: Tianjin Medical University Eye Hospital; Tianjin Medical University Eye Institute; The College of Optometry & Ophthalmology, Tianjin 300384, China.
authors.forename: Bo-Jie
authors.initials: BJ
authors.lastname: Hu
authors.affiliation: Tianjin Medical University Eye Hospital; Tianjin Medical University Eye Institute; The College of Optometry & Ophthalmology, Tianjin 300384, China.
authors.forename: Ju-Ping
authors.initials: JP
authors.lastname: Liu
authors.affiliation: Tianjin Medical University Eye Hospital; Tianjin Medical University Eye Institute; The College of Optometry & Ophthalmology, Tianjin 300384, China.
authors.forename: Xiao-Rong
authors.initials: XR
authors.lastname: Li
keywords: astigmatism; corneal pachymetry; diabetes mellitus; intraocular pressure; vitrectomy