title: Fracture Toughness of Vocal Fold Tissue: A Preliminary Study.
abstract: A customized mechanical tester that slices thin, soft samples was used to measure the fracture toughness of vocal fold tissue. Porcine vocal fold lamina propria was subjected to quasi-static, guillotine-like tests at three equally distanced regions along the anterior-posterior direction. The central one-third where high-velocity collisions between vocal folds occur was found to have the maximum fracture toughness. In contrast, the anterior one-third featured a lower toughness. Fracture toughness can be indicative of the risk of benign and malignant lesions in vocal fold tissue.
authors.affiliation: Biomechanics Laboratory, Department of Mechanical Engineering, McGill University, Montreal, Quebec, Canada. Electronic address: amir.miriramsheh@mail.mcgill.ca.
authors.forename: Amir K
authors.initials: AK
authors.lastname: Miri
authors.affiliation: Biomechanics Laboratory, Department of Mechanical Engineering, McGill University, Montreal, Quebec, Canada.
authors.forename: Lei Xi
authors.initials: LX
authors.lastname: Chen
authors.affiliation: Biomechanics Laboratory, Department of Mechanical Engineering, McGill University, Montreal, Quebec, Canada.
authors.forename: Rosaire
authors.initials: R
authors.lastname: Mongrain
authors.affiliation: Biomechanics Laboratory, Department of Mechanical Engineering, McGill University, Montreal, Quebec, Canada.
authors.forename: Luc
authors.initials: L
authors.lastname: Mongeau
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D055119:Elastic Modulus; D023421:Models, Animal; D009092:Mucous Membrane / Q000293:injuries / Q000473:pathology / Q000503:physiopathology; D010699:Phonation; D013314:Stress, Mechanical; D013552:Swine; D014827:Vocal Cords / Q000293:injuries / Q000473:pathology / Q000503:physiopathology*
keywords: Benign lesions; Fracture toughness; Vocal folds