title: [TESTING STABILITY OF TABLETED ACETAMINOPHEN AND FUROSEMIDE AFTER 6-MONTH STORAGE IN SPACE FLIGHT].
abstract: It was shown that multiple spaceflight factors (i.e., acceleration, overvibration, microgravity etc.) do not impact stability of acetaminophen and furosemide tablets stored onboard the International space station over 6 months. Acetaminophen dose in a tablet was 496.44 ± 6.88 mg (99.29 ± 1.38%) before spaceflight (SF) and 481.77 ± 1 2.40 mg (96.35 ± 0.48%) after 6 mos. of storage; furosemide dose in a tablet was 40.19 ± 0.28 mg (100.47 ± 0.71%) before and 39.24 ± 0.72 mg (98.105 ± 1.80%) after SF remaining within the established limits.
authors.forename: V V
authors.initials: VV
authors.lastname: Bogomolov
authors.forename: S N
authors.initials: SN
authors.lastname: Kondratenko
authors.forename: I V
authors.initials: IV
authors.lastname: Kovachevich
mesh_terms: D000082:Acetaminophen / Q000737:chemistry*; D004356:Drug Storage / Q000379:methods; D005665:Furosemide / Q000737:chemistry*; D006801:Humans; D008422:Materials Testing / Q000379:methods*; D013026:Space Flight; D018531:Spacecraft; D013607:Tablets / Q000737:chemistry; D014893:Weightlessness
chemical_list: D013607:Tablets; D000082:Acetaminophen; D005665:Furosemide