title: Connecting two arrays: the emerging role of actin-microtubule cross-linking motor proteins.
abstract: The cytoskeleton of plant cells, consisting of actin filaments (AFs) and microtubules (MTs), is a central structure for various intracellular processes, such as cell division, isotropic and polar growth, vesicle transport, cell shape, and morphogenesis. Pharmaceutical and genetic studies have provided indications for interdependent cross-talk between the cytoskeletal components. Recent live-cell imaging studies have cemented this notion, in particular when the cytoskeleton rearranges. However, the proteins that directly mediate this cross-talk have remained largely elusive. Recent data indicate that certain proteins can interact with both cytoskeletal arrays at the same time, and hence connecting them. In this review, we summarize the recent literature of the AF- and MT-interactors, mainly focusing on a plant-specific mediator of cytoskeletal cross-talk: the calponin homology (CH) domain-containing kinesin-14 motor proteins (KCHs).
authors.affiliation: Max-Planck-Institute for Molecular Plant Physiology , Potsdam-Golm, Germany.
authors.forename: René
authors.initials: R
authors.lastname: Schneider
authors.affiliation: ARC Centre of Excellence in Plant Cell Walls, School of Botany, University of Melbourne , Parkville, VIC, Australia.
authors.forename: Staffan
authors.initials: S
authors.lastname: Persson
keywords: actin filaments; calponin homology domain; dynein; kinesin-14; microtubules