title: Nonsecretory Multiple Myeloma and AL Amyloidosis Presenting with Nephrotic Range Proteinuria.
abstract: Nonsecretory multiple myeloma (NSMM) is the absence of a detectable monoclonal protein in serum and urine of a multiple myeloma (MM) patient and immunoglobulin light chain (AL) amyloidosis is a significantly rare complication. A case of NSMM with AL amyloidosis and nephrotic range proteinuria is presented. Sharing clinical, therapeutic, and prognostic characteristics with MM, real challenge may be during initial diagnosis of NSMM and assessment of treatment response. In elderly patients with unexplained renal dysfunction, MM should be in the differential diagnosis and the absence of a monoclonal protein should not rule out MM but should remind us of the possibility of NSMM.
authors.affiliation: Department of Internal Medicine, Ufuk University School of Medicine, 06520 Ankara, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Beyler Kilic
authors.affiliation: Department of Internal Medicine, Ufuk University School of Medicine, 06520 Ankara, Turkey.
authors.forename: Ali Kemal
authors.initials: AK
authors.lastname: Oguz
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Ufuk University School of Medicine, 06520 Ankara, Turkey.
authors.forename: Ihsan
authors.initials: I
authors.lastname: Ergun
authors.affiliation: Department of Pathology, Hacettepe University School of Medicine, 06100 Ankara, Turkey.
authors.forename: Dilek Ertoy
authors.initials: DE
authors.lastname: Baydar
authors.affiliation: Division of Hematology, Department of Internal Medicine, Ufuk University School of Medicine, 06520 Ankara, Turkey.
authors.forename: Meltem
authors.initials: M
authors.lastname: Ayli