title: Copeptin in acute coronary syndromes and heart failure management: State of the art and future directions.
abstract: Over the past two decades, the use of multiple biomarkers has changed cardiovascular disease management. Recently, several trials have assessed the diagnostic and prognostic performances of copeptin, especially in patients with heart failure or acute coronary syndromes. Primary results are interesting, with copeptin looking promising for: the management of patients who present at emergency departments early after chest pain onset and the risk stratification of patients with heart failure. The purpose of this article is to review the data on the place of copeptin in the management of patients with chest pain or heart failure.
authors.affiliation: Hôpital cardiologique, centre hospitalier régional et universitaire de Lille, 59037 Lille cedex, France; Faculté de médecine de Lille, 59037 Lille cedex, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Schurtz
authors.affiliation: Hôpital cardiologique, centre hospitalier régional et universitaire de Lille, 59037 Lille cedex, France; Faculté de médecine de Lille, 59037 Lille cedex, France; Inserm UMR744, Institut Pasteur de Lille, 59037 Lille cedex, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Lamblin
authors.affiliation: Hôpital cardiologique, centre hospitalier régional et universitaire de Lille, 59037 Lille cedex, France; Faculté de médecine de Lille, 59037 Lille cedex, France; Inserm UMR744, Institut Pasteur de Lille, 59037 Lille cedex, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Bauters
authors.affiliation: Emergency Department and SAMU, Lille University Hospital, 59037 Lille cedex, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Goldstein
authors.affiliation: Hôpital cardiologique, centre hospitalier régional et universitaire de Lille, 59037 Lille cedex, France; Faculté de médecine de Lille, 59037 Lille cedex, France; Inserm UMR744, Institut Pasteur de Lille, 59037 Lille cedex, France. Electronic address: gilles_lemesle@yahoo.fr.
authors.forename: Gilles
authors.initials: G
authors.lastname: Lemesle
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000175:diagnosis / Q000628:therapy; D015415:Biomarkers; D002637:Chest Pain / Q000209:etiology; D019468:Disease Management; D042241:Early Diagnosis; D005544:Forecasting; D006020:Glycopeptides / Q000097:blood* / Q000378:metabolism; D006333:Heart Failure / Q000097:blood* / Q000628:therapy; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology; D007668:Kidney / Q000503:physiopathology; D015337:Multicenter Studies as Topic; D009203:Myocardial Infarction / Q000097:blood; D009557:Nipecotic Acids / Q000097:blood; D010879:Piperazines / Q000097:blood; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D013997:Time Factors; D020107:Troponin T / Q000097:blood
chemical_list: D015415:Biomarkers; D006020:Glycopeptides; D009557:Nipecotic Acids; D010879:Piperazines; D020107:Troponin T; C048197:copeptins; C063976:N,N'-bis(1-decylnipecotoyl)piperazine
keywords: Acute coronary syndromes; Chest pain; Copeptin; Copeptine; Coronaropathie; Coronary artery disease; Douleur thoracique; Heart failure; Insuffisance cardiaque; Syndrome coronaire aigu