title: Necrotising herpetic retinopathies: a review and progressive outer retinal necrosis case report.
abstract: Necrotising retinopathies can be visually devastating. Most often associated with the viral family Herpesviridae and seen in both immune-competent and immunocompromised hosts, possible complications of necrotising retinopathies include progressive retinal necrosis with or without macular involvement, optic neuropathy and ultimately, secondary retinal detachment. Examples include progressive outer retinal necrosis, acute retinal necrosis and cytomegaloviral retinitis. If diagnosed early and treated aggressively, visual complications can be prevented; however, there is no current consensus on the most appropriate antiviral regimen for each of the different varieties of necrotising herpetic retinopathy. This paper reviews aspects of varieties of necrotising herpetic retinopathy, including pathophysiology, treatment and diagnostic testing.
authors.affiliation: Illinois College of Optometry, Chicago, Illinois, USA.
authors.forename: Erica A
authors.initials: EA
authors.lastname: Ittner
authors.affiliation: Southern California College of Optometry, Marshall B Ketchum University, Fullerton, California, USA.
authors.forename: Raman
authors.initials: R
authors.lastname: Bhakhri
authors.affiliation: Illinois College of Optometry, Chicago, Illinois, USA.
authors.forename: Tricia
authors.initials: T
authors.lastname: Newman
mesh_terms: D000328:Adult; D006563:Herpes Zoster Ophthalmicus / Q000209:etiology; D006566:Herpesviridae Infections / Q000150:complications*; D006801:Humans; D008297:Male; D009336:Necrosis; D012160:Retina / Q000473:pathology*; D012164:Retinal Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D015882:Retinal Necrosis Syndrome, Acute / Q000175:diagnosis / Q000209:etiology
keywords: herpes virus; necrotising herpetic retinopathy; retinal necrosis; uveitis