title: Spontaneous splenic rupture in a patient with congenital afibrinogenemia.
abstract: Afibrinogenemia is a rare bleeding disorder which is observed with an incidence of 1:1 000 000. It is an autosomal recessive disease and occurs as a result of mutation in one of the three genes which code the three polypeptide chains of fibrinogen. Basic clinical findings include spontaneous bleeding, bleeding after minor trauma or due to surgery. Splenic rupture in afibrinogenemia has been reported only in 6 cases so far. In this article, we present a 15-year old congenital afibrinogenemia patient with spontaneous splenic rupture.
authors.affiliation: Department of Pediatrics, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
authors.forename: Baran Cengiz
authors.initials: BC
authors.lastname: Arcagök
authors.affiliation: Department of Pediatrics, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
authors.forename: Nihal
authors.initials: N
authors.lastname: Özdemir
authors.affiliation: Department of Pediatrics, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
authors.forename: Ayşe
authors.initials: A
authors.lastname: Tekin
authors.affiliation: Department of Pediatric Surgery, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
authors.forename: Rahşan
authors.initials: R
authors.lastname: Özcan
authors.affiliation: Department of Pediatric Surgery, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Eliçevik
authors.affiliation: Department of Pediatric Surgery, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
authors.forename: Osman Faruk
authors.initials: OF
authors.lastname: Şenyüz
authors.affiliation: Department of Pediatrics, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
authors.forename: Halit
authors.initials: H
authors.lastname: Çam
authors.affiliation: Department of Pediatrics, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
authors.forename: Tiraje
authors.initials: T
authors.lastname: Celkan
keywords: Spleen rupture; bleeding disorder; congenital afibrinogenemia