title: Generation of iPSC line HEL47.2 from healthy human adult fibroblasts.
abstract: Human iPSC line HEL47.2 was generated from healthy 83-year old male dermal fibroblasts using non-integrative reprogramming method. Reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered using Sendai viruses.
authors.affiliation: Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland. Electronic address: ras.trokovic@helsinki.fi.
authors.forename: Ras
authors.initials: R
authors.lastname: Trokovic
authors.affiliation: Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland.
authors.forename: Jere
authors.initials: J
authors.lastname: Weltner
authors.affiliation: Research Programs Unit, Molecular Neurology, Biomedicum Stem Cell Centre, University of Helsinki, Helsinki, Finland; Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland.
authors.forename: Timo
authors.initials: T
authors.lastname: Otonkoski
mesh_terms: D000328:Adult; D000369:Aged, 80 and over; D002460:Cell Line / Q000166:cytology*; D065150:Cellular Reprogramming / Q000187:drug effects; D005347:Fibroblasts / Q000166:cytology* / Q000187:drug effects; D052816:Foreskin / Q000166:cytology; D006262:Health; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology* / Q000187:drug effects; D000090062:Kruppel-Like Factor 4; D008297:Male; D014157:Transcription Factors / Q000494:pharmacology
chemical_list: C000715467:KLF4 protein, human; D000090062:Kruppel-Like Factor 4; D014157:Transcription Factors