title: [Dissociation of structural and functional parameters of the retina and optic nerve in a patient with Alzheimer's disease (clinical case)].
abstract: Visual impairment is often one of the earliest sings of Alzheimer's disease. This article reports a clinical case of a female patient diagnosed with mild dementia due to Alzheimer's disease. As revealed by a comprehensive examination, her visual fields and visual evoked potentials were markedly changed, while morphometric parameters of the retina and optic nerve appeared normal. Such a significant dissociation of structural and functional parameters may indicate a more proximal involvement of visual pathways in Alzheimer's disease.
authors.affiliation: Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021.
authors.forename: V P
authors.initials: VP
authors.lastname: Erichev
authors.affiliation: Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021.
authors.forename: L A
authors.initials: LA
authors.lastname: Panyushkina
authors.affiliation: Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021.
authors.forename: I A
authors.initials: IA
authors.lastname: Ronzina
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000150:complications*; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D012160:Retina / Q000473:pathology / Q000503:physiopathology; D058609:Visual Field Tests; D014795:Visual Pathways / Q000473:pathology / Q000503:physiopathology