title: An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene.
abstract: Biologically active 4-nitro-substituted 1,3-diaryltriazene, a chemical analogue of 1,3-bis(4'-amidinophenyl)-triazene-berenil®, belongs to the novel, chemically modified class of potent antitumor agents. Its structural characterization by X-ray analysis and 1H NMR spectroscopy is performed to determine molecular overall conformation in view of its possible interaction to DNA.
authors.forename: Krešimir
authors.initials: K
authors.lastname: Molčanov
authors.forename: Slovenko
authors.initials: S
authors.lastname: Polanc
authors.forename: Maja
authors.initials: M
authors.lastname: Osmak
authors.forename: Biserka
authors.initials: B
authors.lastname: Kojić-Prodić
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry; D003461:Crystallography; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D014226:Triazenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000970:Antineoplastic Agents; D014226:Triazenes