title: A Death Notice for In-Vitro-Generated GM-CSF Dendritic Cells?
abstract: Mouse bone marrow cells cultured with GM-CSF are often used to generate dendritic cells (DCs); in this issue of Immunity, Helft et al. (2015) show that this classical method produces heterogeneous populations of myeloid cells that are only distantly related to macrophages and DCs found in vivo.
authors.affiliation: Laboratory of Immunoregulation, VIB Inflammation Research Center, 9000 Ghent, Belgium. Electronic address: martin.guilliams@irc.ugent.be.
authors.forename: Martin
authors.initials: M
authors.lastname: Guilliams
authors.affiliation: Centre d'Immunologie de Marseille-Luminy, UM2 Aix Marseille Université, INSERM, U1104, CNRS UMR7280, 13288 Marseille, France. Electronic address: bernardm@ciml.univ-mrs.fr.
authors.forename: Bernard
authors.initials: B
authors.lastname: Malissen
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000276:immunology*; D003713:Dendritic Cells / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*