title: Anesthetic Management for Left Ventricular Assist Device Implantation Without Using Cardiopulmonary Bypass: Case Series.
abstract: OBJECTIVE
  Ventricular assist devices are an alternative to medical treatment in patients with hemodynamic disturbances related to acute or chronic congestive heart failure. In this case series, we present our anesthesia management for implantation of left ventricular assist device (LVAD) with thoracotomy.
  
  
  METHODS
  Sixteen patients with end-stage heart failure undergoing LVAD implantation via thoracotomy between November 2012 and August 2014 were analyzed prospectively. Preoperative characteristics, intraoperative hemodynamic and respiratory parameters, use of anesthetic and blood products, and durations of mechanical ventilation, hospital, and intensive care stays were recorded.
  
  
  RESULTS
  Sixteen patients (mean age, 54.6 ± 13 years) were investigated. Single-lung ventilation was applied to 2 patients. Cardiopulmonary bypass (CPB) was required in 5 patients. Intraoperative ketamine, midazolam, fentanyl, and rocuronium requirements were 112 ± 63 mg, 5.5 ± 3.5 mg, 438 ± 187 μg, and 179 ± 49 mg, respectively. Requirements of fresh donor blood, fresh frozen plasma, and thrombocyte and erythrocyte suspension were 1.19 ± 1, 1 ± 0.8, 0.44 ± 0.5, and 0.25 ± 0.7 U, respectively. Durations of mechanical ventilation, intensive care unit, and hospital stay were 46 ± 53 hours, 8.2 ± 6.6 days, and 20.5 ± 11.6 days, respectively. Twelve patients were discharged from hospital with full recovery and 2 patients died; 2 patients are still receiving treatment in the hospital.
  
  
  CONCLUSIONS
  A left thoracotomy approach can be used without CPB, because it reduces the incidences of pump complications and blood transfusion. In addition, this case series showed that the implantation of LVAD by thoracotomy can be implemented securely with single-lumen endotracheal tube without single-lung ventilation.
authors.affiliation: Department of Anesthesiology and Reanimation, Ege University Medical Faculty, Department of Anesthesiology and Reanimation, Izmir, Turkey. Electronic address: dr.nursenkaraca@hotmail.com.
authors.forename: N
authors.initials: N
authors.lastname: Karaca
authors.affiliation: Department of Anesthesiology and Reanimation, Ege University Medical Faculty, Department of Anesthesiology and Reanimation, Izmir, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Sahutoglu
authors.affiliation: Department of Anesthesiology and Reanimation, Ege University Medical Faculty, Department of Anesthesiology and Reanimation, Izmir, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Kocabaş
authors.affiliation: Department of Anesthesiology and Reanimation, Ege University Medical Faculty, Department of Anesthesiology and Reanimation, Izmir, Turkey.
authors.forename: B T
authors.initials: BT
authors.lastname: Orhaner
authors.affiliation: Department of Anesthesiology and Reanimation, Ege University Medical Faculty, Department of Anesthesiology and Reanimation, Izmir, Turkey.
authors.forename: F Z
authors.initials: FZ
authors.lastname: Askar
authors.affiliation: Department of Cardiovascular Surgery, Ege University Medical Faculty, Department of Anesthesiology and Reanimation, Izmir, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Ertugay
authors.affiliation: Department of Cardiovascular Surgery, Ege University Medical Faculty, Department of Anesthesiology and Reanimation, Izmir, Turkey.
authors.forename: C
authors.initials: C
authors.lastname: Engin
authors.affiliation: Department of Cardiovascular Surgery, Ege University Medical Faculty, Department of Anesthesiology and Reanimation, Izmir, Turkey.
authors.forename: T
authors.initials: T
authors.lastname: Yagdi
authors.affiliation: Department of Cardiovascular Surgery, Ege University Medical Faculty, Department of Anesthesiology and Reanimation, Izmir, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Ozbaran
mesh_terms: D000328:Adult; D000368:Aged; D000758:Anesthesia; D000777:Anesthetics; D001803:Blood Transfusion; D002315:Cardiopulmonary Bypass; D015331:Cohort Studies; D003422:Critical Care; D005260:Female; D006333:Heart Failure / Q000601:surgery*; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged; D012121:Respiration, Artificial; D013908:Thoracotomy
chemical_list: D000777:Anesthetics