title: Post-streptococcal acute glomerulonephritis complicated by gouty arthritis: a case report.
abstract: Gouty arthritis is uncommon in childhood and adolescence. On the other hand, there has been no report of cases with development of gouty arthritis with post-streptococcal acute glomerulonephritis (PSAGN) in pediatric patients. Here we report the case of a mildly obese 12-year-old boy with PSAGN complicated by gouty arthritis of the left first metatarsophalangeal joint. On follow-up, it was confirmed that as serum C3 level returned to normal, urinary excretion of uric acid increased and serum uric acid level decreased, thereby resolving the burning pain of the left big toe. In this case, not only did renal insufficiency associate with PSAGN but also mild obesity may have led to hyperuricemia and gouty arthritis. In conclusion, clinicians should be aware that PSAGN may be complicated by gouty arthritis in obese pediatric patients.
authors.affiliation: Department of Pediatrics, Tsugaruhoken Medical CO-OP Kensei Hospital, 2-2-1 Noda, Hirosaki, Aomori, 036-8511, Japan. yasutakakuniyoshi@yahoo.co.jp.
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Kuniyoshi
authors.affiliation: Department of Pediatrics, Tsugaruhoken Medical CO-OP Kensei Hospital, 2-2-1 Noda, Hirosaki, Aomori, 036-8511, Japan. azusa1go@lake.ocn.ne.jp.
authors.forename: Azusa
authors.initials: A
authors.lastname: Kamura
authors.affiliation: Department of Pediatrics, Tsugaruhoken Medical CO-OP Kensei Hospital, 2-2-1 Noda, Hirosaki, Aomori, 036-8511, Japan. sumie@xb4.so-net.ne.jp.
authors.forename: Sumie
authors.initials: S
authors.lastname: Yasuda
authors.affiliation: Department of Pediatrics, Tsugaruhoken Medical CO-OP Kensei Hospital, 2-2-1 Noda, Hirosaki, Aomori, 036-8511, Japan. m.tashiro@mocha.ocn.ne.jp.
authors.forename: Makoto
authors.initials: M
authors.lastname: Tashiro
mesh_terms: D000208:Acute Disease; D015210:Arthritis, Gouty / Q000175:diagnosis / Q000382:microbiology*; D002648:Child; D003176:Complement C3 / Q000378:metabolism; D005921:Glomerulonephritis / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D008297:Male; D008683:Metatarsophalangeal Joint / Q000503:physiopathology; D009765:Obesity / Q000150:complications; D010612:Pharyngitis / Q000150:complications / Q000382:microbiology; D013289:Streptococcaceae / Q000302:isolation & purification; D013290:Streptococcal Infections / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology*; D014527:Uric Acid / Q000378:metabolism
chemical_list: D003176:Complement C3; D014527:Uric Acid