title: Changing relationship among clinic, home, and ambulatory blood pressure with increasing age.
abstract: Studies in adults have shown similar levels of home (HBP) and daytime ambulatory blood pressure (dABP), which are lower than clinic blood pressure (CBP) measurements. This study investigated the impact of age on these differences. A total of 642 untreated children, adolescents, and adults referred to a hypertension clinic were evaluated with CBP, HBP, and dABP measurements within 4 weeks (mean age 38.6 ± 19.4 years; range 5-78 years; 61.1% males). In children, dABP was higher than both CBP and HBP. These differences were progressively eliminated with increasing age, and after the age of 30 years, dABP was similar to HBP, and both were lower than CBP. In subjects aged ≥60 years, dABP appeared to be lower than HBP. Age and hypertension appeared to be the main independent predictors of the differences among the three methods.These data suggest that the relationship between office and out-of-office blood pressure measurements is not the same across all age groups and should be taken into account in the evaluation of subjects with elevated blood pressure in clinical practice.
authors.affiliation: Hypertension Center, STRIDE Hellas-7, Third University Department of Medicine, Sotiria Hospital, Athens, Greece. Electronic address: gstergi@med.uoa.gr.
authors.forename: George S
authors.initials: GS
authors.lastname: Stergiou
authors.affiliation: Hypertension Center, STRIDE Hellas-7, Third University Department of Medicine, Sotiria Hospital, Athens, Greece.
authors.forename: Angeliki
authors.initials: A
authors.lastname: Ntineri
authors.affiliation: Hypertension Center, STRIDE Hellas-7, Third University Department of Medicine, Sotiria Hospital, Athens, Greece.
authors.forename: Anastasios
authors.initials: A
authors.lastname: Kollias
authors.affiliation: Hypertension Center, STRIDE Hellas-7, Third University Department of Medicine, Sotiria Hospital, Athens, Greece.
authors.forename: Antonios
authors.initials: A
authors.lastname: Destounis
authors.affiliation: Hypertension Center, STRIDE Hellas-7, Third University Department of Medicine, Sotiria Hospital, Athens, Greece.
authors.forename: Efthimia
authors.initials: E
authors.lastname: Nasothimiou
authors.affiliation: Hypertension Center, STRIDE Hellas-7, Third University Department of Medicine, Sotiria Hospital, Athens, Greece.
authors.forename: Leonidas
authors.initials: L
authors.lastname: Roussias
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012737:Sex Factors; D059466:White Coat Hypertension / Q000453:epidemiology*; D055815:Young Adult
keywords: Adolescents; children; self-measurement; white coat hypertension