title: Rehospitalization in Infants Born < 29 Weeks' Gestation during the First 2 Years of Life: Risk Assessment.
abstract: OBJECTIVE
  This study aims to determine risk factors for rehospitalization in extremely premature infants.
  
  
  METHODS
  A retrospective cohort study of 157 infants born < 29 weeks' gestational age assessing risk factors for rehospitalization through 2 years of life.
  
  
  RESULTS
  Multivariable logistic regression showed that an increasing number of respiratory infections (odds ratio [OR]: 1.8 [1.1-3.1] per infection p = 0.03) and inhaled steroid use at 1 year (OR: 4.0 [1.3-12.1] p = 0.01) were predictive of hospital readmission. Diuretic (OR: 27 [1.01-1,000] p = 0.04) and oxygen (OR: 32 [3.1-333] p = 0.004) use at 1 year were predictive of pediatric intensive care unit admission. The number of respiratory infections (OR: 2.8 [1.7-4.5] p < 0.0001) with reflux/aspiration necessitating G-tube/Nissen fundoplication surgical intervention with or without G-tubes alone (OR: 21.3 [2.9-166.7] p = 0.02 and OR: 22.7 [CI, 2.4-200] p = 0.04) was predictive of increased number of rehospitalizations.
  
  
  CONCLUSIONS
  Key modifiable risk factors identified were reflux/aspiration and ongoing respiratory infections. Critical time periods for diuretic, oxygen, and inhaled steroid use in this population occurred at the age of 1 year.
authors.affiliation: Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
authors.forename: Jane B
authors.initials: JB
authors.lastname: Taylor
authors.affiliation: Department of Pediatrics, University of Kansas School of Medicine at the University of Kansas Medical Center, Kansas City, Kansas.
authors.forename: Mitzi A
authors.initials: MA
authors.lastname: Go
authors.affiliation: Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
authors.forename: Michael F
authors.initials: MF
authors.lastname: Nyp
authors.affiliation: Department of Pediatrics, University of Kansas School of Medicine at the University of Kansas Medical Center, Kansas City, Kansas.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Legino
authors.affiliation: Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
authors.forename: Michael
authors.initials: M
authors.lastname: Norberg
authors.affiliation: Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
authors.forename: Hongying
authors.initials: H
authors.lastname: Dai
authors.affiliation: Department of Pediatrics, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri.
authors.forename: William E
authors.initials: WE
authors.lastname: Truog
mesh_terms: D005260:Female; D005865:Gestational Age; D006801:Humans; D007223:Infant; D062071:Infant, Extremely Premature; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D015999:Multivariate Analysis; D016017:Odds Ratio; D036801:Parturition; D010359:Patient Readmission / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors