title: Bilateral maxillary sinus floor augmentation with tissue-engineered autologous osteoblasts and demineralized freeze-dried bone.
abstract: The pneumatization of the maxillary sinus often results in a lack of sufficient alveolar bone for implant placement. In the last decades, maxillary sinus lift has become a very popular procedure with predictable results. Sinus floor augmentation procedures are generally carried out using autologous bone grafts, bone substitutes, or composites of bone and bone substitutes. However, the inherent limitations associated with each of these, have directed the attention of investigators to new technologies like bone tissue engineering. Bone marrow stromal cells have been regarded as multi-potent cells residing in bone marrow. These cells can be harvested from a person, multiplied outside his body using bioengineering principles and technologies and later introduced into a tissue defect. We present a case where tissue-engineered autologous osteoblasts were used along with demineralized freeze-dried bone for sinus floor augmentation.
authors.affiliation: Department of Oral and Maxillofacial Surgery, YMT Dental College and Hospital, Mumbai, Maharashtra, India.
authors.forename: Aashish
authors.initials: A
authors.lastname: Deshmukh
authors.affiliation: Department of Oral and Maxillofacial Surgery, YMT Dental College and Hospital, Mumbai, Maharashtra, India.
authors.forename: Rinku
authors.initials: R
authors.lastname: Kalra
authors.affiliation: Department of Oral and Maxillofacial Surgery, YMT Dental College and Hospital, Mumbai, Maharashtra, India.
authors.forename: Shruti
authors.initials: S
authors.lastname: Chhadva
authors.affiliation: Department of Oral and Maxillofacial Surgery, YMT Dental College and Hospital, Mumbai, Maharashtra, India.
authors.forename: Angad
authors.initials: A
authors.lastname: Shetye
keywords: Autologous osteoblast implantation; bone grafting; sinus floor augmentation; tissue engineering