title: Addition of Trifluoroborates to Oxetanyl N,O-Acetals: Entry into Spiro and Fused Saturated Heterocycles.
abstract: N,O-Acetals derived from 3-oxetanone and 1,2-amino alcohols undergo addition reactions with alkynyl-, allyl-, allenyl-, and vinylpotassium trifluoroborates. The resulting products undergo cyclization by orthogonal activation of the oxetane and the alkyne to give a diverse set of spiro and fused heterocycles.
authors.affiliation: Department of Chemistry and Applied Biosciences, Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule Zürich, Vladimir-Prelog-Weg 3, CH-8093 Zürich, Switzerland.
authors.forename: Patrick B
authors.initials: PB
authors.lastname: Brady
authors.affiliation: Department of Chemistry and Applied Biosciences, Laboratorium für Organische Chemie, Eidgenössische Technische Hochschule Zürich, Vladimir-Prelog-Weg 3, CH-8093 Zürich, Switzerland.
authors.forename: Erick M
authors.initials: EM
authors.lastname: Carreira