title: "Weighing the risk": Obesity and outcomes following liver transplantation.
abstract: Obesity is on the rise worldwide. As a result, unprecedented rates of patients are presenting with end stage liver disease in the setting of non-alcoholic fatty liver disease (NAFLD) and are requiring liver transplantation. There are significant concerns that the risk factors associated with obesity and the metabolic syndrome might have a detrimental effect on the long term outcomes following liver transplantation. In general, short term patient and graft outcomes for both obese and morbidly obese patients are comparable with that of non-obese patients, however, several studies report an increase in peri-operative morbidity and increased length of stay. Continued studies documenting the long-term outcomes from liver transplantation are needed to further examine the risk of recurrent disease (NAFLD) and also further define the role risk factors such cardiovascular disease might play long term. Effective weight reduction in the post liver transplant setting may mitigate the risks associated with the metabolic syndrome long-term.
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: Trevor W
authors.initials: TW
authors.lastname: Reichman
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: George
authors.initials: G
authors.lastname: Therapondos
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: Maria-Stella
authors.initials: MS
authors.lastname: Serrano
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: John
authors.initials: J
authors.lastname: Seal
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: Rachel
authors.initials: R
authors.lastname: Evers-Meltzer
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: Humberto
authors.initials: H
authors.lastname: Bohorquez
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: Ari
authors.initials: A
authors.lastname: Cohen
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: Ian
authors.initials: I
authors.lastname: Carmody
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: Emily
authors.initials: E
authors.lastname: Ahmed
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: David
authors.initials: D
authors.lastname: Bruce
authors.affiliation: Trevor W Reichman, George Therapondos, Maria-Stella Serrano, John Seal, Rachel Evers-Meltzer, Humberto Bohorquez, Ari Cohen, Ian Carmody, Emily Ahmed, David Bruce, George E Loss, Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA 70121, United States.
authors.forename: George E
authors.initials: GE
authors.lastname: Loss
keywords: Cirrhosis; End stage liver disease; Liver transplantation; Morbid obesity; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Obesity