title: Pharmacokinetics and preliminary safety of high dose linezolid for the treatment of Gram-positive bacterial infections.
authors.affiliation: Pharmacy Department, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain.
authors.forename: Belén
authors.initials: B
authors.lastname: Lopez-Garcia
authors.affiliation: Pharmacy Department, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain; IMIM (Institut Municipal d'investigacions Biomédiques), Barcelona, Spain. Electronic address: Sluque@parcsalutmar.cat.
authors.forename: Sonia
authors.initials: S
authors.lastname: Luque
authors.affiliation: Burns, Trauma & Critical Care Research Centre, The University of Queensland, Brisbane, Australia; Royal Brisbane & Women's Hospital, Brisbane, Australia.
authors.forename: Jason A
authors.initials: JA
authors.lastname: Roberts
authors.affiliation: Pharmacy Department, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain; IMIM (Institut Municipal d'investigacions Biomédiques), Barcelona, Spain; Universitat Autónoma de Barcelona, Barcelona, Spain. Electronic address: Sgrau@parcsalutmar.cat.
authors.forename: Santiago
authors.initials: S
authors.lastname: Grau
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology; D006801:Humans; D000069349:Linezolid / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
chemical_list: D000900:Anti-Bacterial Agents; D000069349:Linezolid
keywords: Critically ill patients; High doses; Linezolid; Pharmacokinetics; Thrombocytopenia