title: The detection of multiple DNA targets with a single probe using a conformation-sensitive acoustic sensor.
abstract: By using an acoustic wave methodology that allows direct sensing of biomolecular conformations, we achieved the detection of multiple target DNAs using a single probe, exploiting the fact that each bound target results in a hybridized product of a different shape.
authors.affiliation: IMBB, FORTH, 100 N. Plastira str., Heraklion, Crete 70013, Greece. gizeli@imbb.forth.gr atsortos@imbb.forth.gr.
authors.forename: Achilleas
authors.initials: A
authors.lastname: Tsortos
authors.forename: Aristea
authors.initials: A
authors.lastname: Grammoustianou
authors.forename: Rena
authors.initials: R
authors.lastname: Lymbouridou
authors.forename: George
authors.initials: G
authors.lastname: Papadakis
authors.forename: Electra
authors.initials: E
authors.lastname: Gizeli
mesh_terms: D000162:Acoustics / Q000295:instrumentation*; D015374:Biosensing Techniques / Q000295:instrumentation*; D004247:DNA / Q000032:analysis*; D015342:DNA Probes / Q000737:chemistry; D035683:MicroRNAs / Q000032:analysis*; D009690:Nucleic Acid Conformation; D009693:Nucleic Acid Hybridization; D058525:Quartz Crystal Microbalance Techniques / Q000295:instrumentation; D013016:Sound
chemical_list: D015342:DNA Probes; D035683:MicroRNAs; D004247:DNA