title: Dimensional changes after immediate implant placement with or without simultaneous regenerative procedures: a systematic review and meta-analysis.
abstract: OBJECTIVE
  To analyse alveolar ridge volume changes after immediate implant placement, with or without a regenerative technique.
  
  
  METHODS
  Studies investigating the effect of immediate implant placement on ridge dimensional changes were identified through an electronic search conducted using MEDLINE (PubMed) and EMBASE. Weighted mean changes (WMC) between baseline and follow-up time were calculated and subgroup analysis was performed according to study design, evaluation method and regenerative strategies.
  
  
  RESULTS
  After immediate implant placement alone WMC of RCTs showed a loss in width and height of 1.1 mm. After flapless immediate implant placement with immediate provisionalization and a graft WMC showed a loss in width and height of 1.02 mm and 0.79 mm, while after flapped immediate implant placement and a graft WMC showed a gain of 1.79 mm. After immediate implant placement plus a non-resorbable membrane WMC showed a loss in height of 0.07 mm. After immediate implant placement plus a resorbable membrane and a graft WMC showed a gain in height of 1.09 mm.
  
  
  CONCLUSIONS
  Immediate implant placement does not seem to counteract alveolar ridge modelling after tooth extraction. Furthermore, the currently available evidence does not allow for any conclusive statements regarding the efficacy of a concomitant regenerative technique in preventing the amount of alveolar reduction.
authors.affiliation: Dentistry, Università "Tor Vergata", Rome, Italy.|Periodontology, Università Vita e Salute, San Raffaele Hospital, Milan.
authors.forename: Marco
authors.initials: M
authors.lastname: Clementini
authors.affiliation: Dentistry, Università "Tor Vergata", Rome, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Tiravia
authors.affiliation: Periodontology, Università Cattolica del Sacro Cuore, Rome, Italy.
authors.forename: Valeria
authors.initials: V
authors.lastname: De Risi
authors.affiliation: Periodontology, Università Cattolica del Sacro Cuore, Rome, Italy.
authors.forename: Gianluca
authors.initials: G
authors.lastname: Vittorini Orgeas
authors.affiliation: Public Health and Infectious Diseases, University of Rome "La Sapienza", Rome, Italy.
authors.forename: Alice
authors.initials: A
authors.lastname: Mannocci
authors.affiliation: Periodontology, Università Vita e Salute, San Raffaele Hospital, Milan.
authors.forename: Massimo
authors.initials: M
authors.lastname: de Sanctis
mesh_terms: D020341:Absorbable Implants; D016301:Alveolar Bone Loss / Q000209:etiology; D000539:Alveolar Process / Q000473:pathology*; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D001861:Bone Regeneration / Q000502:physiology; D016723:Bone Remodeling / Q000502:physiology; D016025:Bone Transplantation / Q000379:methods; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D005500:Follow-Up Studies; D006801:Humans; D057893:Immediate Dental Implant Loading / Q000379:methods; D008567:Membranes, Artificial
chemical_list: D015921:Dental Implants; D008567:Membranes, Artificial
keywords: alveolar ridge preservation; graft; immediate implant; membrane; morphological changes