title: Lymphoma-associated dysimmune polyneuropathies.
abstract: Lymphoma consists of a variety of malignancies of lymphocyte origin. A spectrum of clinical peripheral neuropathy syndromes with different disease mechanisms occurs in about 5% of lymphoma patients. There exists a complex inter-relationship between lymphoproliferative malignancies and autoimmunity. An imbalance in the regulation of the immune system presumably underlies various immune-mediated neuropathies in patients with lymphoma. This article reviews lymphoma and more-or-less well-defined dysimmune neuropathy subgroups that are caused by humoral and/or cell-mediated immune disease mechanisms directed against known or undetermined peripheral nerve antigens.
authors.affiliation: Department of Neurology, Weill Cornell Medical College/New York Presbyterian Hospital, New York, NY 10065-4885, USA. Electronic address: pstuebge@med.cornell.edu.
authors.forename: Joerg-Patrick
authors.initials: JP
authors.lastname: Stübgen
mesh_terms: D015551:Autoimmunity / Q000502:physiology; D006801:Humans; D007154:Immune System Diseases / Q000150:complications*; D008223:Lymphoma / Q000150:complications*; D011115:Polyneuropathies / Q000150:complications / Q000209:etiology / Q000276:immunology
keywords: Autoantibodies; Autoimmunity; Immune-mediated-inflammation–demyelination; Lymphoma; Polyneuropathy