title: Cu/Fe-Cocatalyzed Formation of β-Ketophosphonates by a Domino Knoevenagel-Decarboxylation-Oxyphosphorylation Sequence from Aromatic Aldehydes and H-Phosphonates.
abstract: A domino Knoevenagel-decarboxylation-alkene difunctionalization sequence has been developed for the conversion of benzaldehydes into β-ketophosphonates, catalyzed by a cooperative Cu/Fe system, whereby C-P and C=O bonds are formed simultaneously in a one-pot reaction. The reaction proceeds in good yields and with a broad substrate scope and environmentally benign conditions.
authors.affiliation: Institute of Next Generation Matter Transformation, College of Chemical Engineering at Huaqiao University, 668 Jimei Blvd, Xiamen, Fujian, 361021 (P. R. China), Fax: (+86) 592-6162990.
authors.forename: Mingxin
authors.initials: M
authors.lastname: Zhou
authors.affiliation: College of Materials Science & Engineering, Huaqiao University, 668 Jimei Blvd, Xiamen, Fujian, 361021 (P. R. China).
authors.forename: Yao
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Institute of Next Generation Matter Transformation, College of Chemical Engineering at Huaqiao University, 668 Jimei Blvd, Xiamen, Fujian, 361021 (P. R. China), Fax: (+86) 592-6162990. qsong@hqu.edu.cn.
authors.forename: Qiuling
authors.initials: Q
authors.lastname: Song
keywords: aldehydes; decarboxylation; domino reactions; homogeneous catalysis; phosphonates