title: Operative treatment of degenerative lumbar spine spondylolisthesis.
abstract: BACKGROUND
  Management of degenerative lumbosacral spondylolisthesis with spinal stenosis is still controversial. Surgery is widely used, as well as non-surgical treatment.
  
  
  OBJECTIVE
  To evaluate the clinical results and functional outcome after operative treatment in Grade II and III lumbar spine spondylolisthesis.
  
  
  METHODS
  Twelve patients with symptoms and image-confirmed degenerative spondylolisthesis entered the study. Mean patient age was 57 years. Spondylolisthesis Grade II or III, segment L4-L5 or L5-S1 were evaluated. All patients underwent similar protocols. Operative treatment was decompressive laminectomy, posterior one segment fixation, and fusion with autologous bone grafting. Functional outcome measures were Visual Analog Scale (VAS, 10-point scale) and Oswestry Disability Index (ODI, 100-percent scale) after 6 and 12 months.
  
  
  RESULTS
  Patient follow-up was 12 months. Preoperatively, 7 patients had severe disability according to ODI, 4 had moderate disability. VAS measured 6 and 7 points in 6 patients, lowest score of 4 points and the highest score of 9. After 6 months, ODI showed 5 patients had minimal and 7 had moderate disability; 2 patients had 0 points on the VAS, 2 had a score of 1, 4 had a score of 2, highest score of 4 points. Treatment outcome effects after 1 year were 9 patients with minimal disability, 3 with moderate; VAS - 2 patients with O points, 3 with 1 point, 4 with 2 points.
  
  
  CONCLUSIONS
  Patients with degenerative spondylolisthesis and spinal stenosis treated surgically showed substantially greater improvement in pain and functional outcome during a period of 1 year.
authors.affiliation: University Clinic of Traumatology, Medical Faculty Skopje, R. Macedonia.
authors.forename: I
authors.initials: I
authors.lastname: Kaftandziev
authors.affiliation: University Clinic of Traumatology, Medical Faculty Skopje, R. Macedonia.
authors.forename: S
authors.initials: S
authors.lastname: Trpeski
authors.affiliation: University Clinic of Neurosurgery, Medical Faculty Skopje, R. Macedonia.
authors.forename: V
authors.initials: V
authors.lastname: Filipce
authors.affiliation: University Clinic of Traumatology, Medical Faculty Skopje, R. Macedonia.
authors.forename: O
authors.initials: O
authors.lastname: Arsovski
authors.affiliation: University Clinic of Traumatology, Medical Faculty Skopje, R. Macedonia.
authors.forename: I
authors.initials: I
authors.lastname: Hasani
authors.affiliation: University Clinic of Traumatology, Medical Faculty Skopje, R. Macedonia.
authors.forename: L
authors.initials: L
authors.lastname: Nikolov
authors.affiliation: University Clinic of Traumatology, Medical Faculty Skopje, R. Macedonia.
authors.forename: A
authors.initials: A
authors.lastname: Kaev
mesh_terms: D016025:Bone Transplantation; D015331:Cohort Studies; D019299:Decompression, Surgical; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000150:complications / Q000601:surgery*; D007796:Laminectomy; D008159:Lumbar Vertebrae / Q000601:surgery*; D008875:Middle Aged; D055013:Osteoarthritis, Spine / Q000150:complications / Q000601:surgery*; D011446:Prospective Studies; D013123:Spinal Fusion; D013130:Spinal Stenosis / Q000209:etiology / Q000601:surgery*; D013168:Spondylolisthesis / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome