title: Reduction Mammaplasty Effect on Pulmonary Function and Arterial Blood Gas in the Overweight Female.
abstract: BACKGROUND
  This study sought to prospectively determine whether reduction mammaplasty improves the results of pulmonary function tests (PFTs) and arterial blood gas (ABG) measurements among overweight or obese women with macromastia and assess whether these changes are correlated with participant weight and body mass index (BMI) changes.
  
  
  METHODS
  Thirty women who were overweight or obese and underwent bilateral reduction mammaplasty were included in this study. PFT and ABG measurements were performed within a 4-week period before reduction mammaplasty and 3 months after reduction mammaplasty. The following selected PFT parameters were used to diagnose the restrictive patterns of ventilatory defects: forced vital capacity (FVC), forced expiratory volume at one second (FEV1), the ratio of FEV1 to FVC expressed as a percentage (FEV1/FVC%), and the average FVC flow rate of 25-75 % (FEF 25-75 %). The ABG measurements included PaO2, PaCO2, HCO3, oxygen saturation, and pH.
  
  
  RESULTS
  A significant difference was found between certain preoperative and postoperative PFTs (i.e., predicted FVC%, predicted FEV1% and predicted FEF 25-75 %) and between all of the preoperative and postoperative ABG measurements (pH, PaO2, PaCO2, HCO3, and Sat O2). A significant positive correlation was found between specimen weight and improvements in FEF 25-75 % and Sat O2. A significant positive correlation was found between the percentage reduction in BMI and the improvements in FEF 25-75 % and FVC.
  
  
  CONCLUSIONS
  Overweight or obese women who underwent reduction mammaplasty showed significant improvements in certain PFT and all of the ABG measurements at 3 months after surgery. The more resected breast tissue predicts greater improvements in FEF 25-75 % and Sat O2, and greater reductions in BMI predicted increased improvements in FEF 25-75 % and FVC.
authors.affiliation: Department of Plastic, Reconstructive and Aesthetic Surgery, Namik Kemal University Faculty of Medicine, 59100, Tekirdag, Turkey, mdceber@yahoo.com.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ceber
authors.forename: Adnan
authors.initials: A
authors.lastname: Yuksek
authors.forename: Levent Cem
authors.initials: LC
authors.lastname: Mutlu
authors.forename: Ilhan
authors.initials: I
authors.lastname: Bali
authors.forename: Birol
authors.initials: B
authors.lastname: Topcu
mesh_terms: D000293:Adolescent; D000328:Adult; D001158:Arteries; D001784:Blood Gas Analysis; D001940:Breast / Q000002:abnormalities* / Q000601:surgery; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000209:etiology / Q000601:surgery*; D008168:Lung / Q000503:physiopathology*; D016462:Mammaplasty; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000150:complications / Q000503:physiopathology; D050177:Overweight / Q000097:blood* / Q000150:complications / Q000503:physiopathology*; D011446:Prospective Studies; D012129:Respiratory Function Tests; D055815:Young Adult