title: Corneal Collagen Cross-Linking in Pellucid Marginal Degeneration: 2 Patients, 4 Eyes.
abstract: Purpose. To report the long-term results of corneal collagen cross-linking (CXL) with riboflavin and ultraviolet-A irradiation in 4 eyes of 2 patients affected by pellucid marginal degeneration (PMD). Methods. This study involved the retrospective analysis of 4 eyes of 2 patients with PMD that underwent CXL treatment. Of the eyes, three had only CXL treatment and one had CXL treatment after an intrastromal corneal ring segment implantation. We have pre- and postoperatively evaluated uncorrected distance visual acuity (UDVA), best corrected distance visual acuity (BCDVA), corneal topography (Pentacam), specular microscopy, and pachymetry. Results. Patient 1 was a woman, aged 35, and Patient 2 was a man, aged 33. The right eye of Patient 1 showed an improvement in her BCDVA, from 16/40 to 18/20 in 15 months, and her left eye improved from 12/20 to 18/20 in 20 months. Patient 2's right eye showed an improvement in his BCDVA, from 18/20 to 20/20 in 43 months, and his left eye improved from 16/20 to 18/20 in 22 months. No complications were recorded during or after the treatment. Conclusion. CXL is a safe tool for the management of PMD, and it can help to stop the progression of this disease.
authors.affiliation: Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, Turkey.
authors.forename: Serife
authors.initials: S
authors.lastname: Bayraktar
authors.affiliation: Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, Turkey.
authors.forename: Zafer
authors.initials: Z
authors.lastname: Cebeci
authors.affiliation: Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, Turkey.
authors.forename: Merih
authors.initials: M
authors.lastname: Oray
authors.affiliation: Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University, 34093 Istanbul, Turkey.
authors.forename: Nilufer
authors.initials: N
authors.lastname: Alparslan