title: Stochastic On-Chip Detection of Subpicomolar Concentrations of Silver Nanoparticles.
abstract: We introduce the stochastic amperometric detection of silver nanoparticles on-chip using a microelectrode array. The technique combines the advantages of parallel and low-noise recordings at individually addressable microelectrodes. We demonstrate the detection of subpicomolar concentrations of silver nanoparticles with a diameter of 10 nm at sampling rates in the kilohertz regime for each channel. By comparison to random walk simulations, we show that the sensitivity of a single measurement is mainly limited by adsorption of nanoparticles at the surface of the chips and the measurement time.
authors.affiliation: †Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich, 52425 Jülich, Germany.
authors.forename: Kay J
authors.initials: KJ
authors.lastname: Krause
authors.affiliation: †Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich, 52425 Jülich, Germany.
authors.forename: Alexey
authors.initials: A
authors.lastname: Yakushenko
authors.affiliation: †Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich, 52425 Jülich, Germany.|‡Neuroelectronics, Department of Electrical and Computer Engineering, Technische Universität München, Boltzmannstr. 11, 85748 Garching, Germany.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Wolfrum
mesh_terms: D008029:Lighting / Q000295:instrumentation; D053768:Metal Nanoparticles / Q000032:analysis*; D008839:Microelectrodes; D012834:Silver / Q000032:analysis*; D013269:Stochastic Processes
chemical_list: D012834:Silver