title: Improved survival of patients with hypermutation in uterine serous carcinoma.
abstract: •Uterine serous carcinoma (USC) is an aggressive subtype of endometrial cancer.•Mutations in DNA polymerase ε gene (POLE) are detected in a subset of USC and confer a strong mutator phenotype.•USC patients diagnosed with POLE mutations experience a significantly better prognosis.
authors.forename: Alessandro D
authors.initials: AD
authors.lastname: Santin
authors.forename: Stefania
authors.initials: S
authors.lastname: Bellone
authors.forename: Floriana
authors.initials: F
authors.lastname: Centritto
authors.forename: Joseph
authors.initials: J
authors.lastname: Schlessinger
authors.forename: Richard
authors.initials: R
authors.lastname: Lifton
keywords: Endometrial cancer; Polymerase epsilon somatic mutations; Uterine serous carcinoma