title: Effect of sleeve gastrectomy on type 2 diabetes as an alternative treatment modality to Roux-en-Y gastric bypass: systemic review and meta-analysis.
abstract: BACKGROUND
  Until recently, Roux-en-Y gastric bypass (RYGB) was the most frequently performed procedure in bariatric surgery. In the last decade, sleeve gastrectomy (SG) has emerged as a more popular, simpler, and less morbid form of bariatric surgery.
  
  
  OBJECTIVE
  This study compares the efficacy of SG and RYGB for the treatment of type 2 diabetes mellitus (T2D).
  
  
  METHODS
  Systemic review and meta-analysis.
  
  
  METHODS
  MEDLINE, EMBASE, and the Cochrane Library were searched for entries up to December 2013. Search terms included "Sleeve gastrectomy," "Gastric bypass," and "Type 2 diabetes mellitus." The chosen articles described both "Sleeve gastrectomy" and "Gastric bypass" and included over 1 year of follow-up data. Data analysis was performed with Review Manager 5.2 and SPSS version 20.
  
  
  RESULTS
  The data set is comprised of 3 retrospective clinical studies, 6 prospective clinical studies, and 2 randomized controlled trials (RCTs), which involved 429 patients in the SG group and 428 patients in the RYGB group. In nonrandomized clinical studies, SG displayed similar efficacy in remission of T2D compared with the standard RYGB. In the RCTs, SG had a lower effect than that of RYGB. T2D remission was not correlated with the percent of excess weight loss for either procedure.
  
  
  CONCLUSIONS
  Based on the current evidence, SG has a similar effect on T2D remission as RYGB.
authors.affiliation: Division of Upper Gastrointestinal Surgery, Department of Surgery, Korea University College of Medicine, Seoul, Korea.
authors.forename: Jun-Min
authors.initials: JM
authors.lastname: Cho
authors.affiliation: Institution for Evidence-Based Medicine, the Korean Branch of Australasian Cochrane Center, Department of Preventive Medicine, Korea University College of Medicine, Seoul, Korea.
authors.forename: Hyun Jung
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Bariatric and Metabolic Institute, Section of Minimally-Invasive Surgery, Cleveland Clinic Florida, Weston, Florida.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Lo Menzo
authors.affiliation: Division of Upper Gastrointestinal Surgery, Department of Surgery, Korea University College of Medicine, Seoul, Korea. Electronic address: kugspss@korea.ac.kr.
authors.forename: Sungsoo
authors.initials: S
authors.lastname: Park
authors.affiliation: Bariatric and Metabolic Institute, Section of Minimally-Invasive Surgery, Cleveland Clinic Florida, Weston, Florida.
authors.forename: Samuel
authors.initials: S
authors.lastname: Szomstein
authors.affiliation: Bariatric and Metabolic Institute, Section of Minimally-Invasive Surgery, Cleveland Clinic Florida, Weston, Florida.
authors.forename: Raul J
authors.initials: RJ
authors.lastname: Rosenthal
mesh_terms: D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000628:therapy; D005743:Gastrectomy / Q000379:methods*; D015390:Gastric Bypass / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D009767:Obesity, Morbid / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome; D015431:Weight Loss
keywords: Bariatric surgery; Diabetes; Gastric bypass; Meta-analysis; Remission; Sleeve gastrectomy; Systemic review