title: [New version of classification of pulmonary hypertension].
abstract: Pulmonary hypertension has multifactorial pathophysiology with endothelial dysfunction, vasoconstriction, pulmonary vessel wall remodeling and plexiform lesions contributing to increased pulmonary vascular resistance. Recent studies showed the importance of several mediators in PH pathophysiology, including prostacyclin, nitric oxide, serotonine, endothelin 1, several cytokines, chemokines, as well as members of the transforming growth factor β family (TGF-β). Current article summarizes new classification version of pulmonary hypertension, which was presented at World pulmonary hypertension symposium in 2013. This classification has five main groups with similar pathological findings, hemodynamic characteristics and similar management.
authors.forename: Michael
authors.initials: M
authors.lastname: Aschermann
mesh_terms: D003226:Congresses as Topic; D006801:Humans; D006976:Hypertension, Pulmonary / Q000145:classification*