title: Sweet Is the Memory of Past Troubles: NK Cells Remember.
abstract: Natural killer (NK) cells are important in host defense against tumors and microbial pathogens. Recent studies indicate that NK cells share many features with the adaptive immune system, and like B cells and T cells, NK cells can acquire immunological memory. Here, we review evidence for NK cell memory and the molecules involved in the generation and maintenance of these self-renewing NK cells that provide enhanced protection of the host.
authors.affiliation: Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, 94143-0414, USA.
authors.forename: Deborah W
authors.initials: DW
authors.lastname: Hendricks
authors.affiliation: Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, 94143-0414, USA.
authors.forename: Gundula
authors.initials: G
authors.lastname: Min-Oo
authors.affiliation: Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, 94143-0414, USA. Lewis.Lanier@ucsf.edu.
authors.forename: Lewis L
authors.initials: LL
authors.lastname: Lanier
mesh_terms: D000818:Animals; D006801:Humans; D007156:Immunologic Memory; D007694:Killer Cells, Natural / Q000276:immunology*; D014777:Virus Diseases / Q000276:immunology*