title: [Data of the quantitative orofacial somatosensory functions of healthy subjects and its influence factors analysis].
abstract: OBJECTIVE
  To establish the preliminary somatosensory data stratified by gender, age group, and sites in the trigeminal region through standardized quantitative sensory testing on healthy individuals, and to evaluate the effects of gender, age, and sites on somatosensory functions.
  
  
  METHODS
  The standardised QST battery developed by the German Research Network on Neuropathic Pain consists totally of 13 different parameters. A total of 70 healthy individuals participated. The subjects were stratified into two groups according to age: younger group (16 female, 16 male, age 24-40 years old) and elder group (20 female, 18 male, age 41-69 years old). The test was performed bilaterally over the infraorbital, mental, and hand regions.
  
  
  RESULTS
  The preliminary orofacial somatosensory data stratified by gender, age group, and sites were presented. Female were more sensitive than male for most of the parameters (P<0.05). Age had a significant effect on most of the parameters (P<0.05), the younger group was more sensitive compared with the elder group (P<0.01) for heat pain threshold (HPT): younger group (38.07±2.94) °C, elder group (39.85±3.52) °C; warmth detection threshold (WDT): younger group (1.40±0.74) °C, elder group (1.89±1.14) °C; mechanical detection threshold (MDT): younger group (0.73±1.66) mN, elder group (1.41±2.82) mN; pressure pain threshold (PPT): younger group (171.71±92.51) kPa, elder group (196.36±73.73) kPa; cold pain threshold (CPT): younger group (25.90±5.38) °C, elder group (21.64±6.78) °C; cold detection threshold (CDT): younger group (-0.97±0.55) °C, elder group (-1.36±0.90) °C, and wind-up ratio (WUR): younger group (3.33± 2.20), elder group (2.67±1.68). The inverse results were demonstrated for mechanical pain threshold (MPT): younger group (111.50±88.93) mN, elder group (104.49±94.94) mN; mechanical pain sensitivity (MPS): younger group (6.96±5.61), elder group (8.93±6.53), and vibration detection threshold (VDT): younger group (7.44±0.52) scale, elder group (7.55±0.48) scale (P<0.05). Somatosensory function was site dependent (P<0.001), the two trigeminal sites (infraorbital and mental) were more sensitive than the hand for CDT, HPT, WDT, thermal sensory limen (TSL), MDT, MPT, MPS, and PPT (P<0.001), but the inverse result was observed for VDT (P<0.001).
  
  
  CONCLUSIONS
  The preliminary orofacial somatosensory data of Han Ethnicity stratified by gender, age group, and sites were established. The study evaluated the effects of gender, age and sites on orofacial somatosensory functions by employment standardized quantitative sensory testing.
authors.affiliation: Department of Prosthodontics and Center for Oral Function Diagnosis, Treatment, and Research, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Guang-ju
authors.initials: GJ
authors.lastname: Yang
authors.affiliation: Department of Prosthodontics and Center for Oral Function Diagnosis, Treatment, and Research, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Cao
authors.affiliation: Department of Prosthodontics and Center for Oral Function Diagnosis, Treatment, and Research, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
authors.forename: Xue-ying
authors.initials: XY
authors.lastname: Qin
authors.affiliation: Department of Prosthodontics and Center for Oral Function Diagnosis, Treatment, and Research, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Qiu-fei
authors.initials: QF
authors.lastname: Xie
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D017288:Pain Threshold; D012684:Sensory Thresholds