title: Mucormycosis (zygomycosis) of renal allograft.
abstract: Fungal infection is relatively common among renal transplant recipients from developing countries. Mucormycosis, also known as zygomycosis, is one of the most serious fungal infections in these patients. The most common of presentation is rhino-cerebral. Isolated involvement of a renal allograft is very rare. A thorough search of literature and our medical records yielded a total of 24 cases with mucormycosis of the transplanted kidney. There was an association with cytomegalovirus (CMV) infection and anti-rejection treatment in these patients and most of these transplants were performed in the developing countries from unrelated donors. The outcome was very poor with an early mortality in 13 (54.5%) patients. Renal allograft mucormycosis is a relatively rare and potentially fatal complication following renal transplantation. Early diagnosis, graft nephrectomy and appropriate antifungal therapy may result in an improved prognosis for these patients.
authors.affiliation: Department of Nephrology , Institute of Medical Education and Research , Chandigarh 160 012 , India.
authors.forename: Krishan L
authors.initials: KL
authors.lastname: Gupta
authors.affiliation: Department of Pathology , Postgraduate Institute of Medical Education and Research , Chandigarh 160 012 , India.
authors.forename: Kusum
authors.initials: K
authors.lastname: Joshi
authors.affiliation: Department of Nephrology , Institute of Medical Education and Research , Chandigarh 160 012 , India.
authors.forename: Harbir S
authors.initials: HS
authors.lastname: Kohli
authors.affiliation: Department of Nephrology , Institute of Medical Education and Research , Chandigarh 160 012 , India.
authors.forename: Vivekanand
authors.initials: V
authors.lastname: Jha
authors.affiliation: Department of Nephrology , Institute of Medical Education and Research , Chandigarh 160 012 , India.
authors.forename: Vinay
authors.initials: V
authors.lastname: Sakhuja
keywords: cytomegalovirus infection; immunosuppression; mucormycosis; renal allograft