title: Unipedicular versus bipedicular percutaneous vertebroplasty for osteoporotic vertebral compression fractures: a prospective randomized study.
abstract: BACKGROUND
  Percutaneous vertebroplasty (PVP) typically involves conventional lower-viscosity cement injection via bipedicular approach. Limited evidence is available comparing the clinical outcomes and complications in treating osteoporotic vertebral compression fractures (OVCFs) with PVP using high-viscosity cement through unipedicular or bipedicular approach.
  
  
  METHODS
  Fifty patients with OVCFs were randomly allocated into two groups adopting unipedicular or bipedicular PVP. The efficacy of unipedicular and bipedicular PVP was assessed by comparing operation time, X-ray exposure time, incidence of complications, vertebral height restoration, and improvement of the visual analogue scale (VAS), Oswestry disability index (ODI) and Short Form-36 (SF-36) General Health Survey scores.
  
  
  RESULTS
  The mean operative and exposure time to X-rays in the unipedicular PVP group was less than that of the bipedicular group (p < 0.05). No statistically significant differences were observed in the VAS score, ODI score, SF-36 score, cement leakage rate or vertebral height restoration between the two groups (p > 0.05).
  
  
  CONCLUSIONS
  Unipedicular and bipedicular PVP are safe and effective treatments for OVCF. Compared with bipedicular PVP, unipedicular PVP entails a shorter surgical time and lower X-ray irradiation.
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei Peoples Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, 225001, China. zhangliang6320@sina.com.
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Orthopaedics, Peking University Third Hospital, Beijing, 100191, China. zjliu@bjmu.edu.cn.
authors.forename: Zhongjun
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei Peoples Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, 225001, China. 17374769@qq.com.
authors.forename: Jingcheng
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei Peoples Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, 225001, China. 17374769@qq.com.
authors.forename: Xinmin
authors.initials: X
authors.lastname: Feng
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei Peoples Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, 225001, China. yangjiandong69@qq.com.
authors.forename: Jiandong
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei Peoples Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, 225001, China. typspineyz@163.com.
authors.forename: Yuping
authors.initials: Y
authors.lastname: Tao
authors.affiliation: Department of Orthopedics, Clinical Medical College of Yangzhou University, Subei Peoples Hospital of Jiangsu Province, No.98 Nantong West Road, Yangzhou, 225001, China. dafei8251@163.com.
authors.forename: Shengfei
authors.initials: S
authors.lastname: Zhang
mesh_terms: D000368:Aged; D001843:Bone Cements / Q000009:adverse effects / Q000627:therapeutic use*; D002681:China; D004185:Disability Evaluation; D005260:Female; D017102:Fracture Healing; D050815:Fractures, Compression / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D006304:Health Status; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D061646:Operative Time; D058866:Osteoporotic Fractures / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D010147:Pain Measurement; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies; D011829:Radiation Dosage; D011859:Radiography; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D054854:Vertebroplasty / Q000009:adverse effects / Q000379:methods*; D014783:Viscosity
chemical_list: D001843:Bone Cements