title: NMR illuminates the pathways to ALS.
abstract: A combination of NMR techniques is able to explore the structure of short-lived protein conformations.
authors.affiliation: Center for Integrative Proteomics Research, Rutgers University, Piscataway, United States.
authors.forename: Tao
authors.initials: T
authors.lastname: Xie
authors.affiliation: Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, United States.
authors.forename: Charalampos G
authors.initials: CG
authors.lastname: Kalodimos
mesh_terms: D006801:Humans; D017510:Protein Folding / Q000528:radiation effects*; D013482:Superoxide Dismutase / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D013482:Superoxide Dismutase
keywords: CEST; CPMG relaxation dispersion; E. coli; biophysics; human Cu,Zn superoxide dismutase; non-native oligomers; protein aggregation; structural biology; transient conformations