title: [Clinical and psychopathological factors associated with impulse control disorders in Parkinson's disease].
abstract: BACKGROUND
  Impulse control disorders (ICD) constitute a complication that may arise during the course of Parkinson's disease (PD). Several factors have been linked to the development of these disorders, and their associated severe functional impairment requires specific and multidisciplinary management. The objective of this study was to evaluate the frequency of ICDs and the clinical and psychopathological factors associated with the appearance of these disorders.
  
  
  METHODS
  Cross-sectional, descriptive, and analytical study of a sample of 115 PD patients evaluated to determine the presence of an ICD. Clinical scales were administered to assess disease severity, personality traits, and presence of psychiatric symptoms at the time of evaluation.
  
  
  RESULTS
  Of the 115 patients with PD, 27 (23.48%) displayed some form of ICD; hypersexuality, exhibited by 14 (12.2%), and binge eating, present in 12 (10.1%), were the most common types. Clinical factors associated with ICD were treatment with dopamine agonists (OR: 13.39), earlier age at disease onset (OR: 0.92), and higher score on the UPDRS-I subscale; psychopathological factors with a significant association were trait anxiety (OR: 1.05) and impulsivity (OR: 1.13).
  
  
  CONCLUSIONS
  ICDs are frequent in PD, and treatment with dopamine agonists is the most important risk factor for these disorders. High impulsivity and anxiety levels at time of evaluation, and younger age at disease onset, were also linked to increased risk. However, presence of these personality traits prior to evaluation did not increase risk of ICD.
authors.affiliation: Servicio de Psiquiatría, Hospital Sant Rafael, FIDMAG, Hospital Universitari Vall d'Hebron, CIBERSAM. Departamento de Psiquiatría, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: N
authors.initials: N
authors.lastname: Sáez-Francàs
authors.affiliation: Servicio de Neurología, Hospital Universitari Vall d́Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: G
authors.initials: G
authors.lastname: Martí Andrés
authors.affiliation: Servicio de Psiquiatría, Hospital Sant Rafael, FIDMAG, Hospital Universitari Vall d'Hebron, CIBERSAM. Departamento de Psiquiatría, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: N
authors.initials: N
authors.lastname: Ramírez
authors.affiliation: Servicio de Neurología, Hospital Universitari Vall d́Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: O
authors.initials: O
authors.lastname: de Fàbregues
authors.affiliation: Servicio de Neurología, Hospital Universitari Vall d́Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Álvarez-Sabín
authors.affiliation: Servicio de Psiquiatría, Hospital Universitari Vall d'Hebron, CIBERSAM. Departamento de Psiquiatría, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: M
authors.initials: M
authors.lastname: Casas
authors.affiliation: Servicio de Neurología, Hospital Universitari Vall d́Hebron, Institut de Recerca (VHIR), Universitat Autònoma de Barcelona, Barcelona, España. Electronic address: hernandezvarajorge76@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Hernández-Vara
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000978:Antiparkinson Agents / Q000009:adverse effects / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D007174:Disruptive, Impulse Control, and Conduct Disorders / Q000209:etiology* / Q000523:psychology*; D018491:Dopamine Agonists / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000209:etiology / Q000523:psychology; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology*; D010556:Personality Tests; D012307:Risk Factors
chemical_list: D000978:Antiparkinson Agents; D018491:Dopamine Agonists
keywords: Agonistas dopaminérgicos; Dopaminergic agonists; Enfermedad de Parkinson; Impulse control disorders; Parkinson's disease; Personalidad; Personality; Prevalence; Prevalencia; Psicopatología; Psychopathology; Trastorno del control de los impulsos.