title: Magnetic molecularly imprinted polymer for the efficient and selective preconcentration of diazinon before its determination by high-performance liquid chromatography.
abstract: A molecularly imprinted polymer was selectively applied for solid-phase extraction and diazinon residues enrichment before high-performance liquid chromatography. Diazinon was thermally copolymerized with Fe3 O4 @polyethyleneglycol nanoparticles, methacrylic acid (functional monomer), 2-hydroxyethyl methacrylate (co-monomer), and ethylene glycol dimethacrylate (cross-linking monomer) in the presence of acetonitrile (porogen) and 2,2-azobisisobutyronitrile (initiator). Then, the imprinted diazinon was reproducibly eluted with methanol/acetic acid (9:1, v/v). The sorbent particles were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy. The comprehensive study of variables through experimental design showed that the maximum performance was achieved under these conditions: pH 7, 10 mL sample volume, 15 mg sorbent, 10 min vortex time, 5 min ultrasonic time, 200 μL methanol/acetic acid (9:1, v/v) as eluent, and 5 min desorption time. Under optimized conditions, the molecularly imprinted polymer solid-phase extraction method demonstrated a linear range (0.02-5 g/mL), a correlation coefficient of 0.997, and 0.005 g/mL detection limit.
authors.affiliation: Department of chemistry, Faculty of sciences, Yasouj University, Yasouj, Iran.
authors.forename: Fahimeh
authors.initials: F
authors.lastname: Zare
authors.affiliation: Department of chemistry, Faculty of sciences, Yasouj University, Yasouj, Iran.
authors.forename: Mehrorang
authors.initials: M
authors.lastname: Ghaedi
authors.affiliation: Department of chemistry, Faculty of sciences, Ilam University, Ilam, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Daneshfar
authors.affiliation: Department of chemistry, Faculty of sciences, Yasouj University, Yasouj, Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Ostovan
mesh_terms: D002851:Chromatography, High Pressure Liquid; D003976:Diazinon / Q000737:chemistry / Q000302:isolation & purification*; D008280:Magnetics; D054802:Molecular Imprinting; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*
chemical_list: D011108:Polymers; D003976:Diazinon
keywords: Diazinon; Magnetic molecularly imprinted polymers; Sample preparation; Solid-phase extraction