title: Photoluminescent carbon dots synthesized by microwave treatment for selective image of cancer cells.
abstract: In this work, a simple, low-cost and one-step microwave approach has been demonstrated for the synthesis of water-soluble carbon dots (C-dots). The average size of the resulting C-dots is about 4 nm. From the photoluminescence (PL) measurements, the C-dots exhibit excellent biocompatibility and intense PL with the high quantum yield (QY) at Ca. 25%. Significantly, the C-dots have excellent biocompatibility and the capacity to specifically target the cells overexpressing the folate receptor (FR). These exciting results indicate the as-prepared C-dots are promising biocompatible probe for cancer diagnosis and treatment.
authors.affiliation: School of Chemical Engineering, Changchun University of Technology, Changchun 130012, PR China. Electronic address: yangxudong10@163.com.
authors.forename: Xudong
authors.initials: X
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, PR China.
authors.forename: Xue
authors.initials: X
authors.lastname: Yang
authors.affiliation: School of Chemical Engineering, Changchun University of Technology, Changchun 130012, PR China.
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Li
authors.affiliation: The First Hospital of Jilin University, Changchun 130021, PR China.
authors.forename: Shouying
authors.initials: S
authors.lastname: Li
authors.affiliation: School of Chemical Engineering, Changchun University of Technology, Changchun 130012, PR China.
authors.forename: Yexuan
authors.initials: Y
authors.lastname: Han
authors.affiliation: State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, PR China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, PR China.
authors.forename: Xinyuan
authors.initials: X
authors.lastname: Bu
authors.affiliation: School of Chemical Engineering, Changchun University of Technology, Changchun 130012, PR China.
authors.forename: Chunyan
authors.initials: C
authors.lastname: Su
authors.affiliation: The First Hospital of Jilin University, Changchun 130021, PR China.
authors.forename: Hong
authors.initials: H
authors.lastname: Xu
authors.affiliation: Lab of Polymer Composites Engineering, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
authors.forename: Yingnan
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, PR China. Electronic address: linquan@jlu.edu.cn.
authors.forename: Quan
authors.initials: Q
authors.lastname: Lin
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002460:Cell Line; D003952:Diagnostic Imaging / Q000379:methods; D005456:Fluorescent Dyes / Q000737:chemistry; D005492:Folic Acid / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D049449:Luminescence; D018625:Microscopy, Atomic Force; D046529:Microscopy, Electron, Transmission; D008872:Microwaves; D036103:Nanotechnology / Q000379:methods; D009369:Neoplasms / Q000473:pathology*; D010777:Photochemistry; D045663:Quantum Dots; D012997:Solvents; D014508:Urea / Q000737:chemistry; D014867:Water; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D005456:Fluorescent Dyes; D012997:Solvents; D014867:Water; D002244:Carbon; D014508:Urea; D005492:Folic Acid
keywords: Cancer cells detection; Carbon dots; Fluorescence; Selective image