title: Sensitivity and Reproducibility of Ultrasonography in Calcium Pyrophosphate Crystal Deposition in Knee Cartilage: A Cross-sectional Study.
abstract: OBJECTIVE
  To compare the ability to detect calcium pyrophosphate (CPP) crystals deposition (CPPD) in knee cartilage by ultrasonography (US) and radiography.
  
  
  METHODS
  Patients with knee effusion were consecutively included and underwent radiography and US evaluation of knees. Diagnosis of CPPD was made by the identification of CPP crystals. Two blinded rheumatologists performed US assessment.
  
  
  RESULTS
  We included 51 patients (25 with CPPD). US revealed hyperechoic spots in all 25 patients with CPPD (sensitivity 100%, specificity 92.3%), whereas radiography revealed CPPD in 16 (sensitivity 64%, specificity 100%; p < 0.0001).
  
  
  CONCLUSIONS
  US of knees is more sensitive than radiography for CPPD diagnosis.
authors.affiliation: From the Université Paris Diderot, Service de Rhumatologie, Hôpital Bichat, APHP, Paris, France.S. Ottaviani, MD; P.A. Juge, MD; A. Aubrun, MD; E. Palazzo, MD; P. Dieudé, MD, PhD. sebastien.ottaviani@bch.aphp.fr.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Ottaviani
authors.affiliation: From the Université Paris Diderot, Service de Rhumatologie, Hôpital Bichat, APHP, Paris, France.S. Ottaviani, MD; P.A. Juge, MD; A. Aubrun, MD; E. Palazzo, MD; P. Dieudé, MD, PhD.
authors.forename: Pierre-Antoine
authors.initials: PA
authors.lastname: Juge
authors.affiliation: From the Université Paris Diderot, Service de Rhumatologie, Hôpital Bichat, APHP, Paris, France.S. Ottaviani, MD; P.A. Juge, MD; A. Aubrun, MD; E. Palazzo, MD; P. Dieudé, MD, PhD.
authors.forename: Aurore
authors.initials: A
authors.lastname: Aubrun
authors.affiliation: From the Université Paris Diderot, Service de Rhumatologie, Hôpital Bichat, APHP, Paris, France.S. Ottaviani, MD; P.A. Juge, MD; A. Aubrun, MD; E. Palazzo, MD; P. Dieudé, MD, PhD.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Palazzo
authors.affiliation: From the Université Paris Diderot, Service de Rhumatologie, Hôpital Bichat, APHP, Paris, France.S. Ottaviani, MD; P.A. Juge, MD; A. Aubrun, MD; E. Palazzo, MD; P. Dieudé, MD, PhD.
authors.forename: Philippe
authors.initials: P
authors.lastname: Dieudé
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002358:Cartilage, Articular / Q000000981:diagnostic imaging*; D002805:Chondrocalcinosis / Q000000981:diagnostic imaging*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014463:Ultrasonography
keywords: PSEUDOGOUT; PYROPHOSPHATE; ULTRASOUND