title: International Society for Extracellular Vesicles: first annual meeting, April 17-21, 2012: ISEV-2012.
abstract: Extracellular micro- and nano-scale membrane vesicles produced by different cells are recognised as an essential entity of physiological fluids in a variety of organisms and function as mediators of intercellular communication employed for the regulation of multiple systemic and local processes. In the last decade, an exponential amount of experimental work was dedicated to exploring the biogenesis and secretion mechanisms, physiological and pathological functions and potential applications of the extracellular vesicles (EVs). Noteworthy is the large heterogeneity of in vitro and in vivo models applied, technical approaches developed in these studies and the diversity of designations assigned to different or similar types of EVs. Hence, there is a clear necessity for a uniform nomenclature and standardisation of methods to isolate and characterise these vesicles. In April 2012, the first meeting of the International Society for Extracellular Vesicles (ISEV) took place bringing together this exponentially grown scientific community. The University of Gothenburg (Krefting Research Centre) together with the Interim Board of the Society created in September 2011 (Jan Lötvall, Clotilde Théry, Xandra Breakefield, Marca Wauben, Yong Song Gho, Lawrence Rajendran, Graça Raposo, Douglas Taylor, Margareta Sjöstrand and Esbjörn Telemo) organised this fantastic event that counted 488 registered and contributing participants. This meeting report provides a retrospective summary of the broad spectrum of ISEV-2012 sessions. Again, we emphasise novel findings, discussions and decisions met by the community during the meeting.
authors.affiliation: Department of Medicine and Cell Biology, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, USA.
authors.forename: Elisa
authors.initials: E
authors.lastname: Araldi
authors.affiliation: Department of Molecular Cell Biology, Johannes Gutenberg University Mainz, Mainz, Germany.
authors.forename: Eva-Maria
authors.initials: EM
authors.lastname: Krämer-Albers
authors.affiliation: Department of Biochemistry and Cell Biology, Utrecht University, Utrecht, The Netherlands.
authors.forename: Esther Nolte-'t
authors.initials: EN
authors.lastname: Hoen
authors.affiliation: Departments of Pediatrics, Cell and Developmental Biology, Weill Cornell Medical College, New York, USA.
authors.forename: Hector
authors.initials: H
authors.lastname: Peinado
authors.affiliation: Department of Physics, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Katarzyna Maria
authors.initials: KM
authors.lastname: Psonka-Antonczyk
authors.affiliation: Laboratory for Aging and Cognitive Diseases, European Neuroscience Institute, Göttingen, Germany.
authors.forename: Pooja
authors.initials: P
authors.lastname: Rao
authors.affiliation: Centre de Recherche, Institut Curie, UMR144 CNRS, Paris, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: van Niel
authors.affiliation: Hospital Santa Cristina, Instituto de Investigación Sanitaria Princesa, Madrid, Spain.
authors.forename: María
authors.initials: M
authors.lastname: Yáñez-Mó
authors.affiliation: Department of Environmental Health Sciences, University Medical Centre, Freiburg, Germany; irina.nazarenko@uniklinik-freiburg.de.
authors.forename: Irina
authors.initials: I
authors.lastname: Nazarenko
keywords: ISEV-2012; International Society for Extracellular Vesicles; exosomes; extracelluar membrane vesicles; microparticles; microvesicles