title: Cancer-related Fatigue in Patients with Advanced Cancer Treated with Autonomic Nerve Pharmacopuncture.
abstract: The purpose of this study was to observe the effects of autonomic nerve pharmacopuncture (ANP) treatment on cancer-related fatigue (CRF) in patients with advanced cancer. This observational case study was conducted at the East West Cancer Center of Daejeon University's Dunsan Korean Medical Hospital. Two patients were observed. One patient was diagnosed with left thymic cancer metastatic to the left pleura. The other patient had terminal-stage cervical cancer with iliac bone and lumbar 5 metastases. We injected mountain ginseng pharmacopuncture (MGP) into acupoints alongside the spine (Hua-Tuo-Jia-Ji-Xue, EX B2). We examined the patients for CRF using the Korean version of the Revised Piper Fatigue Scale (RPFS-K), which is a self-assessment tool. The scores on the RPFS-K for both patients tended to decrease during the treatment. Laboratory findings, including hematological changes, were also checked. Liver and renal function tests showed that the treatment was safe. Although further large-population studies are necessary, this case study suggests that ANP has a favorable effect on CRF in patients with advanced cancer.
authors.affiliation: East West Cancer Center, Dunsan Korean Medical Hospital of Daejeon University, Daejeon, South Korea.
authors.forename: Ji-hye
authors.initials: JH
authors.lastname: Park
authors.affiliation: East West Cancer Center, Dunsan Korean Medical Hospital of Daejeon University, Daejeon, South Korea.
authors.forename: Hyung-jun
authors.initials: HJ
authors.lastname: Jeon
authors.affiliation: East West Cancer Center, Dunsan Korean Medical Hospital of Daejeon University, Daejeon, South Korea.
authors.forename: Hwi-joong
authors.initials: HJ
authors.lastname: Kang
authors.affiliation: Graduate School of Health and Sport, Daejeon University, Daejeon, South Korea.
authors.forename: In-Sook
authors.initials: IS
authors.lastname: Jeong
authors.affiliation: East West Cancer Center, Dunsan Korean Medical Hospital of Daejeon University, Daejeon, South Korea.
authors.forename: Chong-kwan
authors.initials: CK
authors.lastname: Cho
authors.affiliation: East West Cancer Center, Dunsan Korean Medical Hospital of Daejeon University, Daejeon, South Korea. Electronic address: altyhs@dju.kr.
authors.forename: Hwa-seung
authors.initials: HS
authors.lastname: Yoo
mesh_terms: D015669:Acupuncture Points; D000328:Adult; D017776:Autonomic Pathways / Q000502:physiology; D005221:Fatigue / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D005894:Panax; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D010936:Plant Extracts
keywords: Hua-Tuo-Jia-Ji-Xue (EX-B2); advanced cancer; autonomic nerve pharmacopuncture; cancer-related fatigue; mountain ginseng pharmacopuncture