title: Precision of SPECT/CT Allows the Diagnosis of a Hidden Brodie's Abscess of the Talus in a Patient with Sickle Cell Disease.
abstract: Brodie's abscess is a rare subacute osteomyelitis that can be found in sickle cell disease along with other bone complications. A 21-year-old female with sickle cell disease was presenting frequently to the medical casualty department for painful vasoocclusive crises and for persistent ankle pain and swelling. Hybrid imaging with single-photon emission computed tomography-computed tomography (SPECT-CT) incidentally revealed Brodie's abscess in the talus bone of the ankle, causing persisting long-standing pain. SPECT-CT is a modern technology used to scan bone to detect both anatomical and functional abnormalities with high specificity. Brodie's abscess is a rare bone inflammation that could be a hidden cause of pain and infection in sickle cell disease. Although rare, this lesion requires more attention in patients with sickle cell disease because their immunocompromised status renders them prone to this infection.
authors.affiliation: Hematology Department, Amiri Hospital, Kuwait City, State of Kuwait.
authors.forename: Hassan
authors.initials: H
authors.lastname: Al-Jafar
authors.affiliation: Nuclear Medicine Department, Farwaniya Hospital, Al-Farwania City, State of Kuwait.
authors.forename: Eman
authors.initials: E
authors.lastname: Al-Shemmeri
authors.affiliation: Faculty of Medicine, Nuclear Medicine Department, Kuwait University, Kuwait, Kuwait.
authors.forename: Jehan
authors.initials: J
authors.lastname: Al-Shemmeri
authors.affiliation: Molecular Imaging Center, Jaber Al-Ahmad Center, Kuwait City, Kuwait.
authors.forename: Leena
authors.initials: L
authors.lastname: Aytglu
authors.affiliation: Nuclear Medicine Department, Farwaniya Hospital, Al-Farwania City, State of Kuwait.
authors.forename: Uzma
authors.initials: U
authors.lastname: Afzal
authors.affiliation: Faculty of Medicine, Nuclear Medicine Department, Kuwait University, Kuwait, Kuwait.
authors.forename: Saud
authors.initials: S
authors.lastname: Al-Enizi
keywords: Brodie’s abscess; SPECT-CT; Sickle cell disease