title: [Therapy of hypertension--2015].
abstract: With an prevalence of 32%, arterial hypertension remains on of the most common diseases among adults in Germany. The ESH/ESC-guidelines from 2013 and the corresponding pocket guidelines of the DHL(®)/DGK from 2014 contain multiple modifications in diagnosis and therapy that are discussed in the present review. Target blood pressure recommendations have been simplified to <140/90 mmHg for almost all hypertensive patients. Exceptions include: diabetic patients, elderly, and patients with chronic kidney disease and proteinuria. The recommendations for pharmacological antihypertensive therapy remained mainly unchanged. Critical evaluation of renal denervation in therapy resistant hypertension requires additional randomized controlled trials in Germany to finally assess the clinical relevance of this intervention. Currently, renal denervation does not provide an alternative strategy for an established pharmacological or non-pharmacological approach.
authors.affiliation: Center for Cardiovascular Research (CCR), Institut für Pharmakologie, Charité - Universitätsmedizin Berlin.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Kintscher
authors.affiliation: Klinik für Innere Medizin III - Kardiologie, Angiologie und internistische Intensivmedizin, Universitätsklinikum des Saarlandes.
authors.forename: Felix
authors.initials: F
authors.lastname: Mahfoud
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001795:Blood Pressure Determination / Q000592:standards; D004351:Drug Resistance; D005858:Germany / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D015995:Prevalence
chemical_list: D000959:Antihypertensive Agents