title: Prediction of Long-Term Survival in Patients with End-Stage Heart Failure Secondary to Ischemic Heart Disease: Surgical Correction and Volumetric Analysis.
abstract: OBJECTIVE
  Ischemic heart disease (IHD) may result in lethal conditions such as ischemic cardiomyopathy (ICM) and mitral regurgitation (MR).
  
  
  METHODS
  We hypothesized preoperative LV volume would be highly associated with long-term survival in such patients. We retrospectively evaluated effects of LV end-systolic volume index (LVESVI) on survival.
  
  
  RESULTS
  Patients were divided into two groups according to LVESVI; Group S (n = 19, <100 ml/m(2)), and L (n = 55, >100 ml/m(2)). There were 74 patients (male 61, female 13; 61 ± 10 y.o.). There was no statistical significance in preoperative parameters, including ejection fraction (EF), severity of MR, severity of tricuspid regurgitation (TR), and right ventricular systolic pressure (RVSP). After operation, LVESVI and severity of MR were statistically reduced in both groups. However, EF, severity of TR and RVSP were not statistically alleviated in both groups. In Group S, 5- and 10-year survival rates were 93% and 48%. In Group L, 5- and 10-year survival rates were 50% and 29%. There was a statistical difference in long-term survival between two groups.
  
  
  CONCLUSIONS
  Preoperative LV volume would be one of the risk factors for long-term survival in patients with congestive heart failure secondary to IHD. Careful follow-up and optimal treatment should be recommended before LV dimension becomes too large.
authors.affiliation: Department of Cardiovascular Surgery, Hayama Heart Center, Miura-gun, Kanagawa, Japan.
authors.forename: Minoru
authors.initials: M
authors.lastname: Yoshida
authors.forename: Masanori
authors.initials: M
authors.lastname: Hirota
authors.forename: Joji
authors.initials: J
authors.lastname: Hoshino
authors.forename: Taichi
authors.initials: T
authors.lastname: Kondo
authors.forename: Tadashi
authors.initials: T
authors.lastname: Isomura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005544:Forecasting; D006333:Heart Failure / Q000209:etiology* / Q000401:mortality* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000601:surgery; D017202:Myocardial Ischemia / Q000150:complications*; D012189:Retrospective Studies; D013318:Stroke Volume