title: Detection of T-Cadherin Expression in Mouse Embryos.
abstract: The aim of the present study was to evaluate T-cadherin expression at the early developmental stages of the mouse embryo. Using in situ hybridization and immunofluorescent staining of whole embryos in combination with confocal microscopy, we found that T-cadherin expression is detected in the developing brain, starting with the E8.75 stage, and in the heart, starting with the E11.5 stage. These data suggest a possible involvement of T-cadherin in the formation of blood vessels during embryogenesis.
authors.affiliation: Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
authors.forename: K A
authors.initials: KA
authors.lastname: Rubina
authors.affiliation: Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
authors.forename: V A
authors.initials: VA
authors.lastname: Smutova
authors.affiliation: Department of Embryology, Biology Faculty, Lomonosov Moscow State University, Leninskie Gory, 1/12, 119234, Moscow, Russia.
authors.forename: M L
authors.initials: ML
authors.lastname: Semenova
authors.affiliation: Division of Developmental Neurobiology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
authors.forename: A A
authors.initials: AA
authors.lastname: Poliakov
authors.affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
authors.forename: S
authors.initials: S
authors.lastname: Gerety
authors.affiliation: Division of Developmental Neurobiology, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
authors.forename: D
authors.initials: D
authors.lastname: Wilkinson
authors.affiliation: Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
authors.forename: E I
authors.initials: EI
authors.lastname: Surkova
authors.affiliation: Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Semina
authors.affiliation: Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
authors.forename: V Yu
authors.initials: VY
authors.lastname: Sysoeva
authors.affiliation: Department of Biochemistry and Molecular Medicine, Faculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovskiy Prosp., 31/5, 119192, Moscow, Russia.
authors.forename: V A
authors.initials: VA
authors.lastname: Tkachuk
keywords: T-cadherin; angiogenesis; embryogenesis; in situ hybridization