title: Does Insert Type Affect Clinical and Functional Outcome in Total Knee Arthroplasty? A Randomised Controlled Clinical Trial With 5-Year Follow-Up.
abstract: New insert types have been developed to improve clinical and functional outcome in mobile bearing (MB-TKA) and fixed bearing total knee arthroplasty (FB-TKA). A prospective single blinded randomised controlled clinical trial was performed to evaluate 2 types of MB-TKA inserts and 2 types of FB-TKA inserts of the Genesis II prosthesis (Smith & Nephew) in 146 patients with 5-years follow-up. A significant difference (P=.042) between the MB-TKA inserts was found in KSS function scores, but clinical significance is expected to be limited. Goniometry, temporal gait parameters and QoL were similar in all groups. Survival was significantly better (P=.047) for FB-TKA. The comparable outcome and higher revision rate in MB-TKA indicate that FB-TKA may be preferential for the Genesis II implant system.
authors.affiliation: CORAL - Centre for Orthopaedic Research Alkmaar, Department of Orthopaedic Surgery, Medical Centre Alkmaar, Wilhelminalaan 12, Alkmaar, The Netherlands.
authors.forename: B L
authors.initials: BL
authors.lastname: Fransen
authors.affiliation: CORAL - Centre for Orthopaedic Research Alkmaar, Department of Orthopaedic Surgery, Medical Centre Alkmaar, Wilhelminalaan 12, Alkmaar, The Netherlands; Move Research Institute, Faculty of Human Movement Sciences, VU University, Van der Boechorststraat 7, Amsterdam, The Netherlands.
authors.forename: Marco J M
authors.initials: MJ
authors.lastname: Hoozemans
authors.affiliation: CORAL - Centre for Orthopaedic Research Alkmaar, Department of Orthopaedic Surgery, Medical Centre Alkmaar, Wilhelminalaan 12, Alkmaar, The Netherlands.
authors.forename: Lucien C M
authors.initials: LC
authors.lastname: Keijser
authors.affiliation: Smith & Nephew Orthopaedics AG, Oberneuhofstrasse 10D, Baar, Switzerland.
authors.forename: Marlies E T
authors.initials: ME
authors.lastname: van Lent
authors.affiliation: Department of Orthopaedic Surgery and Traumatology, Isala Hospital, Dokter van Heesweg 2, Zwolle, The Netherlands.
authors.forename: Cees C P M
authors.initials: CC
authors.lastname: Verheyen
authors.affiliation: CORAL - Centre for Orthopaedic Research Alkmaar, Department of Orthopaedic Surgery, Medical Centre Alkmaar, Wilhelminalaan 12, Alkmaar, The Netherlands.
authors.forename: Bart J
authors.initials: BJ
authors.lastname: Burger
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation*; D005260:Female; D005500:Follow-Up Studies; D005684:Gait; D006801:Humans; D007720:Knee Prosthesis / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011474:Prosthesis Design; D011788:Quality of Life; D012086:Reoperation / Q000706:statistics & numerical data; D016896:Treatment Outcome
keywords: fixed bearing; insert; mobile bearing; reoperation; total knee replacement