title: Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus.
abstract: Three cases of influenza A(H10N8) virus infection in humans have been reported; 2 of these infected persons died. Characterization of the receptor binding pattern of H10 hemagglutinin from avian and human isolates showed that both interact weakly with human-like receptors and maintain strong affinity for avian-like receptors.
authors.forename: Irene
authors.initials: I
authors.lastname: Ramos
authors.forename: Mena
authors.initials: M
authors.lastname: Mansour
authors.forename: Teddy J
authors.initials: TJ
authors.lastname: Wohlbold
authors.forename: Megan E
authors.initials: ME
authors.lastname: Ermler
authors.forename: Ariana
authors.initials: A
authors.lastname: Hirsh
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Runstadler
authors.forename: Ana
authors.initials: A
authors.lastname: Fernandez-Sesma
authors.forename: Florian
authors.initials: F
authors.lastname: Krammer
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D004285:Dogs; D006388:Hemagglutinins / Q000737:chemistry / Q000502:physiology*; D006801:Humans; D065926:Influenza A Virus, H10N8 Subtype / Q000502:physiology*; D061985:Madin Darby Canine Kidney Cells; D011485:Protein Binding; D011991:Receptors, Virus / Q000737:chemistry / Q000502:physiology*; D053585:Virus Attachment; D014779:Virus Replication
chemical_list: D006388:Hemagglutinins; D011991:Receptors, Virus
keywords: avian influenza; emerging influenza; hemagglutinin receptor binding; influenza; influenza A(H10N7); influenza A(H10N8) virus; influenza virus; sialic acid; viruses