title: Factors Associated With Long-Term Weight Loss Following Bariatric Surgery Using 2 Methods for Repeated Measures Analysis.
abstract: We used electronic health record data from 162 patients enrolled in the NUgene Project (2002-2013) to determine demographic factors associated with long-term (from 1 to up to 9.5 (mean = 5.6) years) weight loss following Roux-en-Y gastric bypass surgery. Ninety-nine (61.1%) patients self-reported white, and 63 (38.9%) self-reported black, mixed, or missing race. The average percent weight loss was -33.4% (standard deviation, 9.3) at 1 year after surgery and -30.7% (standard deviation, 12.5) at the last follow-up point. We used linear mixed and semiparametric trajectory models to test the association of surgical and demographic factors (height, surgery age, surgery weight, surgery body mass index, marital status, sex, educational level, site, International Classification of Diseases code, Current Procedural Terminology code, Hispanic ethnicity, and self-reported race) with long-term percent weight loss and pattern of weight loss. We found that black, mixed, and missing races (combined) in comparison with white race were associated with a decreased percent weight loss of -4.31% (95% confidence interval: -7.30, -1.32) and were less likely to have higher and sustained percent weight loss (P = 0.04). We also found that less obese patients were less likely to have higher and sustained percent weight loss (P = 0.01). These findings may be helpful to patients in setting expectations after weight loss surgery.
authors.forename: Abigail S
authors.initials: AS
authors.lastname: Baldridge
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Pacheco
authors.forename: Sharon A
authors.initials: SA
authors.lastname: Aufox
authors.forename: Kwang-Youn A
authors.initials: KY
authors.lastname: Kim
authors.forename: J C
authors.initials: JC
authors.lastname: Silverstein
authors.forename: W
authors.initials: W
authors.lastname: Denham
authors.forename: E
authors.initials: E
authors.lastname: Hungness
authors.forename: Maureen E
authors.initials: ME
authors.lastname: Smith
authors.forename: Norrina B
authors.initials: NB
authors.lastname: Allen
authors.forename: Philip
authors.initials: P
authors.lastname: Greenland
authors.forename: Laura J
authors.initials: LJ
authors.lastname: Rasmussen-Torvik
mesh_terms: D000704:Analysis of Variance; D005260:Female; D005500:Follow-Up Studies; D015390:Gastric Bypass / Q000706:statistics & numerical data*; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000601:surgery*; D057566:Self Report; D013995:Time; D016896:Treatment Outcome; D015431:Weight Loss / Q000208:ethnology*
keywords: Roux-en-Y gastric bypass; bariatric surgery; long-term weight loss; predictors; race; repeated measures