title: Spontaneous regression of interdigitating dendritic sarcoma in a patient with concurrent small lymphocytic lymphoma.
abstract: Interdigitating dendritic cell sarcoma (IDCS) is a rare tumour; only seven cases of IDCS associated with chronic lymphocytic leucaemia/small lymphocytic lymphoma (CLL/SLL) have been reported. We present the case of a 60-year-old man who presented with fevers, night sweats and significant unintentional weight loss. Investigations led to a diagnosis of synchronous SLL and IDCS. Subsequent fluorodeoxyglucose (FDG) positron emission tomography CT (PET-CT) imaging revealed an unusual clinical course with spontaneously resolving highly metabolic lesions. After 42 months of follow-up, the patient remains free of clinical symptoms and evidence of IDCS.
authors.affiliation: Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
authors.forename: Tamer
authors.initials: T
authors.lastname: Khashab
authors.affiliation: Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
authors.forename: Lalit
authors.initials: L
authors.lastname: Sehgal
authors.affiliation: Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
authors.forename: L Jeffrey
authors.initials: LJ
authors.lastname: Medeiros
authors.affiliation: Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
authors.forename: Felipe
authors.initials: F
authors.lastname: Samaniego
mesh_terms: D002471:Cell Transformation, Neoplastic; D054739:Dendritic Cell Sarcoma, Interdigitating / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D005334:Fever / Q000209:etiology; D019788:Fluorodeoxyglucose F18 / Q000008:administration & dosage / Q000378:metabolism; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology; D049268:Positron-Emission Tomography / Q000379:methods; D019275:Radiopharmaceuticals / Q000008:administration & dosage / Q000378:metabolism; D012075:Remission, Spontaneous; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D015431:Weight Loss
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18