title: Thinking beyond the treatment effect in screening for lung cancer.
abstract: In the optimism surrounding screening for lung cancer, the downsides of screening should not be ignored. The article examines the dark side of screening, which is not an unmitigated good.
authors.affiliation: Department of Radiology, University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104. Electronic address: saurabh.jha@uphs.upenn.edu.
authors.forename: Saurabh
authors.initials: S
authors.lastname: Jha
mesh_terms: D055088:Early Detection of Cancer / Q000706:statistics & numerical data* / Q000639:trends; D019317:Evidence-Based Medicine; D005189:False Positive Reactions; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000401:mortality* / Q000517:prevention & control; D000069342:Medical Overuse / Q000517:prevention & control* / Q000706:statistics & numerical data* / Q000639:trends; D015995:Prevalence; D018570:Risk Assessment; D015996:Survival Rate; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data* / Q000639:trends; D014481:United States / Q000453:epidemiology
keywords: Lung cancer; Lung-RADS; NLST; false positives; lead time bias; overdiagnosis