title: [Magnetic resonance and extramural vascular invasion in patients with rectal cancer and liver metastases].
abstract: BACKGROUND
  Extramural vascular invasion (EMVI) in patients with rectal cancer (RC) is associated with more locally advanced tumors, and independently predicts local and distant recurrence and poor overall survival.
  
  
  OBJECTIVE
  To determine the association between EMVI and synchronous liver metastases in patients with RC.
  
  
  METHODS
  We performed a retrospective cohort study including patients with cancer of middle and lower rectum, which were evaluated with magnetic resonance (MRI) for initial staging in the period from January 2011 to January 2012 inclusive. All patients were evaluated with MRI for EMVI and were followed for a year to detect synchronous liver metastases by imaging methods (January 2012 to January 2013 inclusive). Multivariate analysis was performed by logistic regression.
  
  
  RESULTS
  We included 68 patients. Twenty had liver metastases during the observation period (29.41%), of whom 15 had signs of MRI EMVI (75%). The incidence of synchronous liver metastases had a marginally significant association with the presence of EMVI (RR 3.35, 95% CI: 1.0001-11.2187, P = 0.050).
  
  
  CONCLUSIONS
  The presence of MRI EVMI is a poor prognostic predictor factor of development of synchronous liver metastases in patients with RC.
authors.forename: Alberto
authors.initials: A
authors.lastname: Seehaus
authors.forename: Carlos
authors.initials: C
authors.lastname: Vaccaro
authors.forename: Marcos
authors.initials: M
authors.lastname: Quadrelli
authors.forename: Mariana
authors.initials: M
authors.lastname: Calvo
authors.forename: Gustavo
authors.initials: G
authors.lastname: Rossi
authors.forename: Lorena
authors.initials: L
authors.lastname: Savluk
authors.forename: Juan
authors.initials: J
authors.lastname: Pablo Santino
authors.forename: Guillermo
authors.initials: G
authors.lastname: Ojea Quintana
authors.forename: Ricardo
authors.initials: R
authors.lastname: García Mónaco
mesh_terms: D015331:Cohort Studies; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis; D012004:Rectal Neoplasms / Q000473:pathology*; D012189:Retrospective Studies; D019043:Vascular Neoplasms / Q000473:pathology*