title: Stereoselective fate kinetics of chiral neonicotinoid insecticide paichongding in aerobic soils.
abstract: Man-made chemicals such as pesticides, when released into the soil environment, are transformed into extractable residue (ER), bound residue (BR), or mineralized. These processes all play a pivotal role in the risk assessment for the use of man-made chemicals. In this study, BR, ER, and mineralization of a novel chiral pesticide, paichongding (IPP), 1-((6-chloropyridin-3-yl)methyl)-7-methyl-8-nitro-5-propoxy-1,2,3,5,6,7-hexahydro-imidazo[1,2-a]pyridine, were investigated in different soils under aerobic conditions. Significant specificity was observed for diastereoisomers of IPP in the formation of BR or mineralization in neutral and alkaline soils. In contrast, no significant difference was found between enantiomers. The overall mineralization was less than 8% of the applied radioactivity and was related to soil pH. Our findings suggest that the environmental fate of chiral pesticides may be influenced by many factors such as soil properties (e.g. pH). More comprehensive and individualized risk assessments should be carried out for individual stereoisomers of a chiral product.
authors.affiliation: Institute of Nuclear Agricultural Sciences, Zhejiang University, Hangzhou 310029, China; Department of Environmental Sciences, University of California, Riverside, CA 92521, USA.
authors.forename: Qiuguo
authors.initials: Q
authors.lastname: Fu
authors.affiliation: Institute of Nuclear Agricultural Sciences, Zhejiang University, Hangzhou 310029, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.affiliation: Institute of Nuclear Agricultural Sciences, Zhejiang University, Hangzhou 310029, China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Wang
authors.affiliation: Institute of Nuclear Agricultural Sciences, Zhejiang University, Hangzhou 310029, China; Current address: Department of Health Sciences and Technology, Institute of Food, Nutrition and Health, ETH Zürich, Schmelzbergstrasse 9, 8092 Zürich, Switzerland.
authors.forename: Jianbo
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Institute of Nuclear Agricultural Sciences, Zhejiang University, Hangzhou 310029, China.
authors.forename: Jiajun
authors.initials: J
authors.lastname: Shen
authors.affiliation: Shanghai Key Lab of Chemical Biology, East China University of Science and Technology, Shanghai 200237, China.
authors.forename: Zhong
authors.initials: Z
authors.lastname: Li
authors.affiliation: Institute of Nuclear Agricultural Sciences, Zhejiang University, Hangzhou 310029, China. Electronic address: qfye@zju.edu.cn.
authors.forename: Qingfu
authors.initials: Q
authors.lastname: Ye
mesh_terms: D000332:Aerobiosis; D053961:Azabicyclo Compounds / Q000032:analysis / Q000737:chemistry*; D002250:Carbon Radioisotopes; D007306:Insecticides / Q000032:analysis / Q000737:chemistry*; D007700:Kinetics; D008903:Minerals; D015394:Molecular Structure; D010573:Pesticide Residues / Q000032:analysis / Q000737:chemistry*; D011725:Pyridines / Q000032:analysis / Q000737:chemistry*; D012987:Soil / Q000737:chemistry*; D012988:Soil Microbiology; D012989:Soil Pollutants / Q000032:analysis / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D053961:Azabicyclo Compounds; D002250:Carbon Radioisotopes; D007306:Insecticides; D008903:Minerals; D010573:Pesticide Residues; D011725:Pyridines; D012987:Soil; D012989:Soil Pollutants; C588015:paichongding
keywords: (14)C tracer technique; Bound residue; Diastereoselective; Mineralization; Pesticide