title: Influencing factors of immediate angiographic results in intracranial aneurysms patients after endovascular treatment.
abstract: The purpose of this study was to analyze influencing factors associated with immediate angiographic results in intracranial aneurysms patients after endovascular treatment (EVT), providing theoretical evidence and guidance for clinical treatment of intracranial aneurysms. Totally 529 patients met the inclusive criteria, consisting of 338 males and 191 females. Gender; age; history of hypertension, diabetes, and smoking; intracranial atherosclerosis; rupture status, size and location, features of aneurysmal neck, shapes; vasospasm; treatment modality; and degree of aneurysm occlusion were all carefully and completely recorded. All data were investigated in univariate and multivariate logistic regression model to determine whether they were correlated with the degree of aneurysm occlusion. According to aneurysm size, aneurysms were classified as micro-miniature, miniature, and large aneurysms. There were 451 narrow-neck aneurysms and 78 wide-neck aneurysms. Totally 417 were regular and 112 were irregular. And 125 were un-ruptured aneurysms; 404 were ruptured aneurysms. The modalities of treatment were as follows: embolization with coil (n = 415), stent-assisted coil embolization (n = 89), and balloon-assisted coil embolization (n = 25). Univariate analysis showed that aneurysm size, feature of aneurysm neck, shape, and rupture status might affect the immediate occlusion after EVT. Multivariate logistic regression analysis indicated that ruptured aneurysm, tiny aneurysm, and wide-neck aneurysm were independent influencing factors of complete occlusion of intracranial aneurysm. Aneurysm rupture status, size, feature of aneurysmal neck, and shape might be the independent influencing factors of immediate angiographic results in intracranial aneurysm patients after EVT. Un-ruptured, micro-miniature, narrow-neck, and regular-shaped aneurysms were more probable to be occluded completely.
authors.affiliation: Department of Neurosurgery, Guangzhou Red Cross Hospital, The Fourth Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China.|Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Avenue, Haizhu District, Guangzhou, 510282, People's Republic of China.|Key Laboratory on Brain Function Repair and Regeneration of Guangdong, Institute of Neurosurgery, Southern Medical University, Guangzhou, 510200, Guangdong, People's Republic of China.
authors.forename: Jia-Xiang
authors.initials: JX
authors.lastname: Chen
authors.affiliation: Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Avenue, Haizhu District, Guangzhou, 510282, People's Republic of China.|Key Laboratory on Brain Function Repair and Regeneration of Guangdong, Institute of Neurosurgery, Southern Medical University, Guangzhou, 510200, Guangdong, People's Republic of China.
authors.forename: Ling-Feng
authors.initials: LF
authors.lastname: Lai
authors.affiliation: Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Avenue, Haizhu District, Guangzhou, 510282, People's Republic of China.|Key Laboratory on Brain Function Repair and Regeneration of Guangdong, Institute of Neurosurgery, Southern Medical University, Guangzhou, 510200, Guangdong, People's Republic of China.
authors.forename: Kuang
authors.initials: K
authors.lastname: Zheng
authors.affiliation: Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Avenue, Haizhu District, Guangzhou, 510282, People's Republic of China.|Key Laboratory on Brain Function Repair and Regeneration of Guangdong, Institute of Neurosurgery, Southern Medical University, Guangzhou, 510200, Guangdong, People's Republic of China.
authors.forename: Guo-Xiong
authors.initials: GX
authors.lastname: Li
authors.affiliation: Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Avenue, Haizhu District, Guangzhou, 510282, People's Republic of China.|Key Laboratory on Brain Function Repair and Regeneration of Guangdong, Institute of Neurosurgery, Southern Medical University, Guangzhou, 510200, Guangdong, People's Republic of China.
authors.forename: Xu-Ying
authors.initials: XY
authors.lastname: He
authors.affiliation: Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Avenue, Haizhu District, Guangzhou, 510282, People's Republic of China.|Key Laboratory on Brain Function Repair and Regeneration of Guangdong, Institute of Neurosurgery, Southern Medical University, Guangzhou, 510200, Guangdong, People's Republic of China.
authors.forename: Liang-Ping
authors.initials: LP
authors.lastname: Li
authors.affiliation: Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Avenue, Haizhu District, Guangzhou, 510282, People's Republic of China. duanchuanzhi715@126.com.|Key Laboratory on Brain Function Repair and Regeneration of Guangdong, Institute of Neurosurgery, Southern Medical University, Guangzhou, 510200, Guangdong, People's Republic of China. duanchuanzhi715@126.com.
authors.forename: Chuan-Zhi
authors.initials: CZ
authors.lastname: Duan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging* / Q000628:therapy; D001921:Brain / Q000000981:diagnostic imaging*; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D015607:Stents; D016896:Treatment Outcome; D055815:Young Adult
keywords: Endovascular treatment; Intracranial aneurysm; Occlusion