title: Prevalence and specificity of Baeyer-Villiger monooxygenases in fungi.
abstract: Out of 107 fungal strains belonging to three phyla (Ascomycota, Basidiomycota and Zygomycota) and 46 genera, 86 exhibited Baeyer-Villiger monooxygenase (BVMO) activity against racemic bicyclo[3.2.0]heptenone. The strains were classified into three "profiles" based on regio- and enantioselectivity. Statistical analyses of our results, extended by literature data, showed that these profiles could be related to the taxonomic classification of the strains, and suggest that the BVMOs from the Zygomycota phylum may be different in their primary structures from established ones.
authors.affiliation: Laboratory of Biotechnology, National Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, Slovenia.
authors.forename: Lorena
authors.initials: L
authors.lastname: Butinar
authors.affiliation: Laboratory of Biotechnology, National Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, Slovenia.
authors.forename: Martina
authors.initials: M
authors.lastname: Mohorčič
authors.affiliation: Aix Marseille Université, Centrale Marseille, CNRS, Institut des Sciences Moléculaires de Marseille UMR7313, 13397 Marseille, France.
authors.forename: Valérie
authors.initials: V
authors.lastname: Deyris
authors.affiliation: Aix Marseille Université, Centrale Marseille, CNRS, Institut des Sciences Moléculaires de Marseille UMR7313, 13397 Marseille, France.
authors.forename: Katia
authors.initials: K
authors.lastname: Duquesne
authors.affiliation: Aix Marseille Université, Centrale Marseille, CNRS, Institut des Sciences Moléculaires de Marseille UMR7313, 13397 Marseille, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Iacazio
authors.affiliation: Aix Marseille Université, Laboratoire d'Instrumentation et de Sciences Analytiques EA 4672, 13397 Marseille, France.
authors.forename: Magalie
authors.initials: M
authors.lastname: Claeys-Bruno
authors.affiliation: Laboratory of Biotechnology, National Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, Slovenia.
authors.forename: Josepha
authors.initials: J
authors.lastname: Friedrich
authors.affiliation: Aix Marseille Université, Centrale Marseille, CNRS, Institut des Sciences Moléculaires de Marseille UMR7313, 13397 Marseille, France. Electronic address: v.alphand@univ-amu.fr.
authors.forename: Véronique
authors.initials: V
authors.lastname: Alphand
mesh_terms: D001203:Ascomycota / Q000201:enzymology / Q000235:genetics / Q000378:metabolism; D001487:Basidiomycota / Q000201:enzymology / Q000235:genetics / Q000378:metabolism; D001643:Bridged Bicyclo Compounds / Q000737:chemistry*; D023281:Genomics; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D015995:Prevalence; D017524:Slovenia; D013379:Substrate Specificity
chemical_list: D001643:Bridged Bicyclo Compounds; D006899:Mixed Function Oxygenases
keywords: Ascomycetes; Baeyer–Villiger monooxygenase; Basidiomycetes; Enantioselectivity; Fungi; Phylum; Regioselectivity; Screening; Zygomycetes