title: [Incidental finding of a cardiac paraganglioma].
abstract: Cardiac paragangliomas are extremely rare neoplasms with an incidence of 1% of all cardiac tumors and can be completely asymptomatic, therefore, diagnosis is difficult. This article reports the case of an 18-year-old man with a heart murmur detected during a routine physical examination. Echocardiography revealed a heart tumor measuring 7 cm in size in the right atrium. Due to the tumor size and the threat of tricuspid valve insufficiency, tumor resection was performed. The histopathological examination revealed a cardiac paraganglioma with positive reactions of the tumor cells for chromogranin A, synaptophysin and CD56. Differentiating a primary cardiac paraganglioma from other more common cardiac tumors and particularly from metastases of neuroendocrine neoplasms from other locations is essential not only for the further clinical treatment but also for the prognosis of the patient.
authors.affiliation: Institut für Pathologie, Akademisches Lehrkrankenhaus Feldkirch, Carinagasse 47, 6800, Feldkirch, Österreich, christina.steger@lkhf.at.
authors.forename: C M
authors.initials: CM
authors.lastname: Steger
authors.forename: G
authors.initials: G
authors.lastname: Laufer
authors.forename: P L
authors.initials: PL
authors.lastname: Moser
authors.forename: F A
authors.initials: FA
authors.lastname: Offner
authors.forename: N
authors.initials: N
authors.lastname: Bonaros
mesh_terms: D000293:Adolescent; D019002:CD56 Antigen / Q000032:analysis; D053379:Chromogranin A / Q000032:analysis; D004452:Echocardiography; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000473:pathology; D006337:Heart Murmurs / Q000000981:diagnostic imaging; D006338:Heart Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D033162:Incidental Findings; D008297:Male; D010235:Paraganglioma / Q000000981:diagnostic imaging / Q000473:pathology*; D011379:Prognosis; D016708:Synaptophysin / Q000032:analysis
chemical_list: D019002:CD56 Antigen; D053379:Chromogranin A; C522918:NCAM1 protein, human; D016708:Synaptophysin