title: Brain pathways to recovery from alcohol dependence.
abstract: This article highlights the research presentations at the satellite symposium on "Brain Pathways to Recovery from Alcohol Dependence" held at the 2013 Society for Neuroscience Annual Meeting. The purpose of this symposium was to provide an up to date overview of research efforts focusing on understanding brain mechanisms that contribute to recovery from alcohol dependence. A panel of scientists from the alcohol and addiction research field presented their insights and perspectives on brain mechanisms that may underlie both recovery and lack of recovery from alcohol dependence. The four sessions of the symposium encompassed multilevel studies exploring mechanisms underlying relapse and craving associated with sustained alcohol abstinence, cognitive function deficit and recovery, and translational studies on preventing relapse and promoting recovery. Gaps in our knowledge and research opportunities were also discussed.
authors.affiliation: National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA. Electronic address: Changhai.cui@nih.gov.
authors.forename: Changhai
authors.initials: C
authors.lastname: Cui
authors.affiliation: National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
authors.forename: Antonio
authors.initials: A
authors.lastname: Noronha
authors.affiliation: National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
authors.forename: Kenneth R
authors.initials: KR
authors.lastname: Warren
authors.affiliation: National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA; Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA, USA.
authors.forename: George F
authors.initials: GF
authors.lastname: Koob
authors.affiliation: Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: Rajita
authors.initials: R
authors.lastname: Sinha
authors.affiliation: Department of Neurology, University of Missouri, Columbia, MO, USA.
authors.forename: Mahesh
authors.initials: M
authors.lastname: Thakkar
authors.affiliation: National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
authors.forename: John
authors.initials: J
authors.lastname: Matochik
authors.affiliation: Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
authors.forename: Fulton T
authors.initials: FT
authors.lastname: Crews
authors.affiliation: Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA.
authors.forename: L Judson
authors.initials: LJ
authors.lastname: Chandler
authors.affiliation: Neuroscience Program, Center for Health Science, SRI International, Menlo Park, CA, USA.
authors.forename: Adolf
authors.initials: A
authors.lastname: Pfefferbaum
authors.affiliation: Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA.
authors.forename: Howard C
authors.initials: HC
authors.lastname: Becker
authors.affiliation: Laboratory of Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
authors.forename: David
authors.initials: D
authors.lastname: Lovinger
authors.affiliation: Behavioural and Clinical Neuroscience Institute, Department of Psychology, University of Cambridge, Cambridge, UK.
authors.forename: Barry J
authors.initials: BJ
authors.lastname: Everitt
authors.affiliation: National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Egli
authors.affiliation: Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA, USA.
authors.forename: Chitra D
authors.initials: CD
authors.lastname: Mandyam
authors.affiliation: Neurobehavioral Research, Inc., Ala Moana Pacific Center, Honolulu, HI, USA.
authors.forename: George
authors.initials: G
authors.lastname: Fein
authors.affiliation: Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
authors.forename: Marc N
authors.initials: MN
authors.lastname: Potenza
authors.affiliation: Waggoner Center for Alcohol and Addiction Research, University of Texas, Austin, TX, USA.
authors.forename: R Adron
authors.initials: RA
authors.lastname: Harris
authors.affiliation: Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Grant
authors.affiliation: Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA, USA.
authors.forename: Marisa
authors.initials: M
authors.lastname: Roberto
authors.affiliation: Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
authors.forename: Dieter J
authors.initials: DJ
authors.lastname: Meyerhoff
authors.affiliation: Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.
authors.forename: Edith V
authors.initials: EV
authors.lastname: Sullivan
mesh_terms: D000437:Alcoholism / Q000503:physiopathology* / Q000523:psychology*; D016739:Behavior, Addictive / Q000503:physiopathology; D001921:Brain / Q000378:metabolism / Q000502:physiology*; D003071:Cognition / Q000187:drug effects / Q000502:physiology; D006801:Humans; D009434:Neural Pathways / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology*; D009473:Neuronal Plasticity / Q000187:drug effects; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology* / Q000523:psychology*
keywords: Abstinence; Alcohol dependence; Neuroadaptation; Neurocircuitry; Recovery; Withdrawal