title: Bone mineral density measurements in otosclerosis using dual-energy X-ray absorptiometry.
abstract: OBJECTIVE
  This study aims to evaluate patients with otosclerosis with respect to bone mineral density (BMD) at different regions of interest (ROI), using dual-energy X-ray absorptiometry (DXA).
  
  
  METHODS
  Cross-sectional controlled study.
  
  
  METHODS
  Tertiary referral hospital.
  
  
  METHODS
  The patients with a definite diagnosis of otosclerosis confirmed intra-operatively were defined as the study group (n = 30). The control group consisted of volunteer, healthy subjects with normal hearing (n = 43).
  
  
  METHODS
  Following an audiometric evaluation, a venous blood sample was obtained and a single BMD measurement using DXA was applied to each participant.
  
  
  RESULTS
  The mean BMD, T and Z scores were higher in the otosclerosis group than in the control group in all the regions considered, but not significantly; only the L2-L3 lateral BMD and its T and Z scores were significant (P = 0.036, P = 0.029 and P = 0.036, respectively).
  
  
  CONCLUSIONS
  This study shows that the BMD does not decrease in the presence of otosclerosis despite its genetic and metabolic relevance with osteoporosis. Concerning the L2-L3 lateral BMD measurements, the BMD increased in otosclerosis.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Medical Faculty, Abant Izzet Baysal University, Golkoy, Turkey.
authors.forename: S B
authors.initials: SB
authors.lastname: Tonuk
authors.affiliation: Department of Otolaryngology Head & Neck Surgery, Medical Faculty, Abant Izzet Baysal University, Golkoy, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Koybasi
authors.affiliation: Department of Otolaryngology Head & Neck Surgery, Medical Faculty, Abant Izzet Baysal University, Golkoy, Turkey.
authors.forename: Y O
authors.initials: YO
authors.lastname: Bicer
authors.affiliation: Department of Otolaryngology Head & Neck Surgery, Medical Faculty, Abant Izzet Baysal University, Golkoy, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Alkan Temel
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D001299:Audiometry; D015519:Bone Density; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D049449:Luminescence; D008297:Male; D010040:Otosclerosis / Q000097:blood / Q000000981:diagnostic imaging*; D010281:Parathyroid Hormone / Q000097:blood; D014807:Vitamin D / Q000097:blood
chemical_list: D010281:Parathyroid Hormone; D014807:Vitamin D