title: Fibrosarcoma arising from gouty tophi: report of a unique case and review of literature.
abstract: Fibrosarcoma is a malignant mesenchymal tumor. To the author's best knowledge, no previous case of fibrosarcoma arising from gouty tophi has been reported. Here we reported the first case of fibrosarcoma arising from gouty tophi. A case of 58-year-old man was presented with a mass with ulcer and infection in the second joint of left middle finger for 2 months, with long standing gouty tophi. The tumor was biopsied and the biopsy showed complete excision of the tumor. With the pathological and immunohistochemical features considered, the diagnosis of fibrosarcoma associated with gouty tophi was made. The clinical findings, pathological characteristics and treatment were described.
authors.affiliation: Department of Pathology, Jinling Hospital, Medical School of Nanjing University Nanjing, Jiangsu, P. R. China.
authors.forename: Jian-Jun
authors.initials: JJ
authors.lastname: Wang
authors.affiliation: Department of Pathology, Jinling Hospital, Medical School of Nanjing University Nanjing, Jiangsu, P. R. China.
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Wang
authors.affiliation: Department of Pathology, Jinling Hospital, Medical School of Nanjing University Nanjing, Jiangsu, P. R. China.
authors.forename: Kai
authors.initials: K
authors.lastname: Cheng
authors.affiliation: Department of Pathology, Jinling Hospital, Medical School of Nanjing University Nanjing, Jiangsu, P. R. China.
authors.forename: Xuan
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Pathology, Jinling Hospital, Medical School of Nanjing University Nanjing, Jiangsu, P. R. China.
authors.forename: Bo
authors.initials: B
authors.lastname: Yu
authors.affiliation: Department of Pathology, Jinling Hospital, Medical School of Nanjing University Nanjing, Jiangsu, P. R. China.
authors.forename: Shan-Shan
authors.initials: SS
authors.lastname: Shi
authors.affiliation: Department of Pathology, Jinling Hospital, Medical School of Nanjing University Nanjing, Jiangsu, P. R. China.
authors.forename: Xiao-Jun
authors.initials: XJ
authors.lastname: Zhou
authors.affiliation: Department of Pathology, Jinling Hospital, Medical School of Nanjing University Nanjing, Jiangsu, P. R. China.
authors.forename: Qun-Li
authors.initials: QL
authors.lastname: Shi
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis / Q000235:genetics; D001706:Biopsy; D005354:Fibrosarcoma / Q000737:chemistry / Q000209:etiology* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D005384:Finger Joint / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006073:Gout / Q000150:complications* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000209:etiology* / Q000235:genetics / Q000473:pathology / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor
keywords: Fibrosarcoma; gout; gouty tophi; sarcoma