title: 18-Fluoro-deoxyglucose-PET/Computed Tomography in Infection and Aseptic Inflammatory Disorders: Value to Patient Management.
abstract: This communication is aimed specifically at exploring the possible practical advantages and potentials of 18-fluoro-deoxyglucose (FDG)-PET/ computed tomography (CT) that could translate into routine management of patients with infection and aseptic inflammatory disorders. From viewpoint of patient management, the applications can be classified into two broad categories, based upon primary intent of the investigation: [a] Diagnostic (eg, pyrexia of unknown origin and other localized infectious processes) and [b] Undertaking this as part of objective imaging assessment of early treatment response and thereby tailoring/altering therapy (eg, systemic infectious and non-infectious inflammatory diseases). Over the last decade, this promising FDG-PET/CT application has been debated and there is need to make systematic approach for defining its value to patient management.
authors.affiliation: Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe, Jerbai Wadia Road, Parel, Mumbai, Maharashtra 400012, India. Electronic address: drsanb@yahoo.com.
authors.forename: Sandip
authors.initials: S
authors.lastname: Basu
authors.affiliation: Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe, Jerbai Wadia Road, Parel, Mumbai, Maharashtra 400012, India.
authors.forename: Rohit
authors.initials: R
authors.lastname: Ranade
mesh_terms: D019468:Disease Management; D005335:Fever of Unknown Origin / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007239:Infections / Q000000981:diagnostic imaging*; D007249:Inflammation / Q000000981:diagnostic imaging*; D064847:Multimodal Imaging / Q000379:methods*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed / Q000379:methods*; D051598:Whole Body Imaging / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: 18-fluoro-deoxyglucose–PET/computed tomography; Infection; Inflammation; Pyrexia of unknown origin