title: Slow Progression of Poorly Differentiated Gastric Carcinoma Associated with Epstein-Barr Virus Infection: 12-year Follow-up.
abstract: Epstein-Barr virus (EBV)-associated gastric carcinoma accounts for nearly 10% of all gastric carcinomas and has distinct demographic, clinical and pathological features compared with EBV-negative gastric carcinoma. We herein report the case of a patient with EBV-associated gastric carcinoma followed up for 12 years during the natural course of the disease. The appearance of the tumor on gastroscopy and computed tomography gradually changed, and the size of the lesion increased very slowly during the 12 years, without metastasis. The present case indicates that some EBV-associated gastric carcinomas progress very slowly.
authors.affiliation: Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Japan.
authors.forename: Rina
authors.initials: R
authors.lastname: Yoza
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Ueda
authors.forename: Yojiro
authors.initials: Y
authors.lastname: Sakuma
authors.forename: Naoki
authors.initials: N
authors.lastname: Minami
authors.forename: Ken
authors.initials: K
authors.lastname: Takahashi
authors.forename: Sachiko
authors.initials: S
authors.lastname: Minamiguchi
authors.forename: Hironori
authors.initials: H
authors.lastname: Haga
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Chiba
mesh_terms: D018450:Disease Progression; D020031:Epstein-Barr Virus Infections / Q000150:complications* / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D005743:Gastrectomy; D005773:Gastroscopy; D006396:Hematemesis / Q000209:etiology; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013274:Stomach Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology* / Q000821:virology*; D014057:Tomography, X-Ray Computed