title: Self-assembly pathway of peptide nanotubes formed by a glutamatic acid-based bolaamphiphile.
abstract: The self-assembly of peptide nanotubes formed by an L-glutamic acid-based bolaamphiphile is shown to proceed via a remarkable mechanism where the peptide conformation changes from β-sheet to unordered. The kinetics of this process are elucidated via X-ray scattering and UV circular dichroism methods. The reverse transition from "unordered" to β-sheet structures is triggered by UV radiation.
authors.affiliation: Centro de Ciéncias Naturais e Humanas, Universidade Federal do ABC, Santo André 09210-580, Brazil. ersilva@ufabc.edu.br.
authors.forename: Emerson Rodrigo
authors.initials: ER
authors.lastname: da Silva
authors.forename: Wendel Andrade
authors.initials: WA
authors.lastname: Alves
authors.forename: Valeria
authors.initials: V
authors.lastname: Castelletto
authors.forename: Mehedi
authors.initials: M
authors.lastname: Reza
authors.forename: Janne
authors.initials: J
authors.lastname: Ruokolainen
authors.forename: Rohanah
authors.initials: R
authors.lastname: Hussain
authors.forename: Ian William
authors.initials: IW
authors.lastname: Hamley
mesh_terms: D002942:Circular Dichroism; D005663:Furans / Q000737:chemistry*; D018698:Glutamic Acid / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D045333:Nanotubes, Peptide / Q000737:chemistry* / Q000648:ultrastructure; D017433:Protein Structure, Secondary; D011728:Pyridones / Q000737:chemistry*; D053838:Scattering, Small Angle; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D005663:Furans; D045333:Nanotubes, Peptide; D011728:Pyridones; C543575:bolaamphiphile; D018698:Glutamic Acid