title: The role of sports and exercise in allergic disease: drawbacks and benefits.
abstract: Although training and exercise have several benefits, overdoing it might not necessarily be a good thing. For instance, elite athletes have an increased risk for asthma and allergy. Several mechanisms can be implicated for this risk, which include the interplay between environmental training factors and athlete's personal risk factors, such as genetic susceptibility, neurogenic-mediated inflammation, and epithelial sensitivity. However, an overwhelming amount of scientific evidence shows the positive effects of sports as part of a healthy lifestyle. Training reduces breathlessness and asthma symptoms and attenuates Th2-mediated inflammatory responses. Taken together, the benefits far outweigh the potential hazards of training. An easily administered therapeutic healthy lifestyle intervention, which could be used alongside current treatment, must be developed.
authors.affiliation: Centro Hospitalar São João & Faculty of Medicine, University of Porto, Portugal, Europe.
authors.forename: Diana
authors.initials: D
authors.lastname: Silva
authors.forename: André
authors.initials: A
authors.lastname: Moreira
mesh_terms: D001249:Asthma / Q000276:immunology / Q000503:physiopathology; D015444:Exercise / Q000502:physiology*; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology* / Q000503:physiopathology*; D007107:Immune System / Q000276:immunology / Q000502:physiology; D018448:Models, Immunological; D013177:Sports / Q000502:physiology*; D013550:Swimming / Q000502:physiology
keywords: asthma; athletes; exercise; physical activity; sports