title: Low grade serious carcinoma of the peritoneum in a BRCA1 carrier previously diagnosed with a "low-grade serous tubal intra-epithelial carcinoma" (STIC) on risk reducing surgery.
abstract: •Conventional definitions of STIC do not capture all lesions associated with serous neoplasia and the presence of abnormal p53 expression may be helpful diagnostically.•The management of STICs and tubal atypias remain uncertain.•The POINT Project is a registry set up to address this critical gap in knowledge.
authors.affiliation: Department of Medical Oncology, BC Cancer Agency, Canada.
authors.forename: Wen Yee
authors.initials: WY
authors.lastname: Chay
authors.affiliation: Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
authors.forename: Hugo M
authors.initials: HM
authors.lastname: Horlings
authors.affiliation: Department of Medical Oncology, BC Cancer Agency, Canada.
authors.forename: Anna V
authors.initials: AV
authors.lastname: Tinker
authors.affiliation: Department of Medical Oncology, BC Cancer Agency, Canada.
authors.forename: Karen A
authors.initials: KA
authors.lastname: Gelmon
authors.affiliation: Vancouver General Hospital, BC, Canada ; University of British Columbia, Pathology and Laboratory Medicine, Canada.
authors.forename: C Blake
authors.initials: CB
authors.lastname: Gilks
keywords: BRCA; Prophylactic salpingo-oophorectomy; Serous carcinoma; Serous tubal intraepithelial carcinoma; Tubal atypia