title: Primary adrenal leiomyosarcoma: a case report and review of literature.
abstract: Primary adrenal leiomyosarcoma (PAL) is an extremely rare mesenchymal tumors and originates from the smooth muscle wall of the central adrenal vein and its branches. Herein we report a case of a 49-year-old female suffering from PAL. Computed tomography revealed a well-circumscribed heterogeneously mass measuring 6 × 5 × 5 cm located in the left suprarenal areal, and a left laparoscopic adrenalectomy was underwent. Microscopic examination showed a hypercellular tumor with intersecting fascicled of spindled cells. Immunohistochemical staining showed that the cells were positive for desmin, smooth muscle actin (SMA), vimentin and negative for CD34, CD117, S100, Bcl-2 and Dog1. No oncological treatment underwent after surgery, and the patient had no recurrence or metastasis at 6 months postoperatively.
authors.affiliation: Department of Urology, The Third Xiangya Hospital of Central South University Changsha 410013, P. R. China.
authors.forename: Yihong
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Department of Urology, The Third Xiangya Hospital of Central South University Changsha 410013, P. R. China.
authors.forename: Yuxin
authors.initials: Y
authors.lastname: Tang
authors.affiliation: Department of Urology, The Third Xiangya Hospital of Central South University Changsha 410013, P. R. China.
authors.forename: Jin
authors.initials: J
authors.lastname: Tang
authors.affiliation: Department of Urology, The Third Xiangya Hospital of Central South University Changsha 410013, P. R. China.
authors.forename: Fei
authors.initials: F
authors.lastname: Deng
authors.affiliation: Department of Pathology, School of Basic Medical Science, Central South University Changsha 410013, P.R. China.
authors.forename: Guanghui
authors.initials: G
authors.lastname: Gong
authors.affiliation: Department of Urology, The Third Xiangya Hospital of Central South University Changsha 410013, P. R. China.
authors.forename: Yingbo
authors.initials: Y
authors.lastname: Dai
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D000315:Adrenalectomy / Q000379:methods; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010535:Laparoscopy; D007890:Leiomyosarcoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D047368:Tumor Burden
chemical_list: D014408:Biomarkers, Tumor
keywords: Adrenal gland; adrenal gland neoplasms; leiomyosarcoma