title: High-speed scanning interferometric focusing by fast measurement of binary transmission matrix for channel demixing.
abstract: Using the fast measurement of a binary transmission matrix and a digital micromirror device, we demonstrate high-speed interferometric focusing through highly dynamic scattering media with binary intensity modulation. The scanning of speckles for reference optimization gives stable focusing, which can be used for focusing through a fast changing media or two dimensional scanning through a slowly changing scattering media. The system allows dynamic focusing at 12.5 Hz with 1024 input modes, and more than 60 times intensity enhancement. It was tested with a moving diffuser, a mouse brain and skull tissue. The experiment with a live drosophila embryo shows its potential in compensating dynamic scattering in live biological tissue.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Tao
authors.forename: Dare
authors.initials: D
authors.lastname: Bodington
authors.forename: Marc
authors.initials: M
authors.lastname: Reinig
authors.forename: Joel
authors.initials: J
authors.lastname: Kubby
mesh_terms: D000818:Animals; D001921:Brain / Q000033:anatomy & histology; D004331:Drosophila melanogaster / Q000196:embryology; D004625:Embryo, Nonmammalian / Q000033:anatomy & histology; D007368:Interferometry / Q000379:methods*; D051379:Mice; D055620:Optical Phenomena; D012542:Scattering, Radiation; D013997:Time Factors