title: [Screening interview for early detection of high-functioning autism spectrum disorders].
abstract: OBJECTIVE
  Various different questionnaires are available for the screening of autism spectrum disorders (ASD). These screening instruments show high sensitivity and are able to identify a large number of individuals with ASD, but they lack the specificity to differentiate individuals with ASD from those children and adolescents with other complex neurobehavioural disorders (such as attention-deficit/hyperactivity disorder, emotional disorders, and others), especially for those without intellectual disabilities.
  
  
  METHODS
  The present study evaluates the data of 309 individuals (153 with high-functioning ASD, 156 with other psychiatric disorders, IQ > 70) to find out whether selected items of the ADI-R can be used for an economic and sensitive screening of high-functioning ASD.
  
  
  RESULTS
  The results show that 8 items of the ADI-R can be used to discriminate high-functioning ASD and other psychiatric disorders. A cutoff of 5 led to a sensitivity of 0.93 and a cutoff of 6 to a specificity of 0.74.
  
  
  CONCLUSIONS
  The combination of early onset, serious abnormalities in social contact with stereotyped or compulsive-ritualized behaviour or interests can be detected with few interview questions for screening of ASD. Nevertheless, a more detailed and specific assessment in an expert setting should follow the screening process.
authors.affiliation: 1 Klinik für Kinder- und Jugendpsychiatrie, Psychosomatik und Psychotherapie der Phillips-Universität Marburg.
authors.forename: Wiebke
authors.initials: W
authors.lastname: Hoffmann
authors.forename: Monika
authors.initials: M
authors.lastname: Heinzel-Gutenbrunner
authors.forename: Katja
authors.initials: K
authors.lastname: Becker
authors.forename: Inge
authors.initials: I
authors.lastname: Kamp-Becker
mesh_terms: D000293:Adolescent; D020817:Asperger Syndrome / Q000175:diagnosis* / Q000523:psychology; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis* / Q000523:psychology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007389:Internal-External Control; D007406:Interview, Psychological; D008297:Male; D008403:Mass Screening / Q000706:statistics & numerical data; D011594:Psychometrics / Q000706:statistics & numerical data; D012372:ROC Curve; D012917:Social Adjustment; D055815:Young Adult
keywords: Asperger syndrome; Asperger-Syndrom; Autismus; Diagnostik; Screening; autism; diagnosis; screening