title: Factors Affecting Medium-Term Outcomes After Crural Angioplasty in Critically Ischemic Legs.
abstract: OBJECTIVE
  To study factors affecting patency and medium-term outcomes after crural angioplasty.
  
  
  METHODS
  All crural angioplasties between March 2003 and September 2010 were reviewed from a prospective database to analyze primary patency, amputation-free survival, and limb salvage.
  
  
  RESULTS
  Five hundred and twenty-seven limbs in 478 patients (58.7% male, mean age 73.9 ± 0.53 years) were treated. In all, 49.1% were diabetic patients and 7.4% were dialysis dependent. Primary patency was 65.5%, 57.8%, 48.5%, and 32.9% at 1, 6, 12, and 36 months, respectively. Amputation-free survival was 75.2% at 1 year and 59.0% at 3 years. Limb salvage at 3 years was 92.7%. Rutherford categories 5 and 6 had a consistent adverse effect on patency. This led to an adverse amputation-free survival and limb salvage at 3 years.
  
  
  CONCLUSIONS
  Crural angioplasty is an effective treatment for limb salvage. Its outcomes are adversely affected by diabetes, renal disease, coronary disease, and worsening Rutherford grade.
authors.affiliation: Department of Vascular Surgery, Queen Elizabeth Hospital, Birmingham, United Kingdom.
authors.forename: K
authors.initials: K
authors.lastname: Mathur
authors.affiliation: Department of Vascular Surgery, Queen Elizabeth Hospital, Birmingham, United Kingdom.
authors.forename: M K
authors.initials: MK
authors.lastname: Ayyappan
authors.affiliation: Wolfson Computer Laboratory, Queen Elizabeth Hospital, Birmingham, United Kingdom.
authors.forename: J
authors.initials: J
authors.lastname: Hodson
authors.affiliation: Department of Interventional Vascular Radiology, Queen Elizabeth Hospital, Birmingham, United Kingdom.
authors.forename: J
authors.initials: J
authors.lastname: Hopkins
authors.affiliation: Department of Vascular Surgery, Queen Elizabeth Hospital, Birmingham, United Kingdom.
authors.forename: A
authors.initials: A
authors.lastname: Tiwari
authors.affiliation: Department of Interventional Vascular Radiology, Queen Elizabeth Hospital, Birmingham, United Kingdom.
authors.forename: M
authors.initials: M
authors.lastname: Duddy
authors.affiliation: Department of Vascular Surgery, Queen Elizabeth Hospital, Birmingham, United Kingdom rajiv@vohra.org.uk.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Vohra
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical; D000800:Angioplasty, Balloon / Q000009:adverse effects; D016638:Critical Illness; D016208:Databases, Factual; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D053208:Kaplan-Meier Estimate; D023821:Limb Salvage; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D014654:Vascular Patency
keywords: critical ischemia; crural angioplasty; limb salvage; patency; survival; tibial