title: NF-κB signaling in B-1 cell development.
abstract: NF-κB transcription factors play essential roles in hematopoiesis. In this review, we summarize the requirements of different components of the NF-κB pathway for B-1 cell development and maintenance. The B-1 cell developmental steps are also reviewed, with particular emphasis on stages where NF-κB signaling may be critical.
authors.affiliation: Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Gabriel K
authors.initials: GK
authors.lastname: Pedersen
authors.affiliation: Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Monika
authors.initials: M
authors.lastname: Ádori
authors.affiliation: Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Gunilla B
authors.initials: GB
authors.lastname: Karlsson Hedestam
mesh_terms: D000818:Animals; D016175:B-Lymphocyte Subsets / Q000502:physiology*; D055786:Gene Knockout Techniques; D006801:Humans; D016328:NF-kappa B / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D016328:NF-kappa B
keywords: B-1a cells; B-1b cells; IκB; IκBNS; LUBAC; NEMO