title: Nasal heterotopia versus pilocytic astrocytoma: A narrow border.
abstract: Failure of the anterior neuropore can lead to three main types of anomalies: nasal dermal sinus, encephalocele and nasal glioma or heterotopia. In this report, we describe a case of intracranial and extracranial glial heterotopia that probably resulted from a common failure of anterior neuropore development. We describe the prenatal radiological assessment based on ultrasound and MRI results, and consider their limitation for early fetal diagnosis. We also discuss the embryogenesis and the possible pathogenic mechanisms involved.
authors.affiliation: Department of Pediatrics, University of Liège, Liège, Belgium. Electronic address: ellouzenesrine24@gmail.com.
authors.forename: N
authors.initials: N
authors.lastname: Ellouze
authors.affiliation: Department of Neurosurgery, CHR Citadelle, Liège, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Born
authors.affiliation: Department of Pediatric Oncology, CHR Citadelle, Liège, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Hoyoux
authors.affiliation: Neuropathology, VUB, Brussels, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Michotte
authors.affiliation: Department of Gynecology, CHR Citadelle, Liège, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Retz
authors.affiliation: Department of Radiology, CHR Citadelle, Liège, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Tebache
authors.affiliation: Department of Pediatric Oncology, CHR Citadelle, Liège, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Piette
mesh_terms: D001254:Astrocytoma / Q000175:diagnosis / Q000601:surgery*; D003937:Diagnosis, Differential; D004677:Encephalocele / Q000175:diagnosis / Q000601:surgery; D005910:Glioma / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D009669:Nose Neoplasms / Q000175:diagnosis / Q000601:surgery*
keywords: Approche neurochirurgicale; Astrocytome pilocytique; Encéphalocèle frontonasal; Frontonasal encephalocele; Glial heterotopia; Hétérotopie gliale; Imagerie prénatale; Neurosurgical approach; Pilocytic astrocytoma; Prenatal imagery