title: Myxoinflammatory Fibroblastic Sarcoma: A Radiographical, Pathological, and Immunohistochemical Report of Rare Malignancy.
abstract: Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare, painless, and intermediate (rarely metastasizing) fibroblastic tumor, which commonly occurs in the extremities, with an equal sex predilection. This sarcoma is composed of a mixed inflammatory infiltrate along with spindled, epithelioid, and bizarre tumor cells in a background of hyaline and myxoid areas. In spite of such a distinctive morphology, the tumor can be a diagnostic challenge, simulating inflammatory conditions as well as neoplastic nature. For accurate diagnosis, the tumor requires extensive clinical, radiological, and pathological investigations. We present a case of MIFS in a 19-year-old female who presented with a mass in the left ankle. After appropriate excision and postoperative radiation therapy, she is free of disease, including recurrence and metastasis, at 12 years postoperatively.
authors.affiliation: Department of Orthopedic Surgery, Gifu Municipal Hospital, 7-1 Kashima-cho, Gifu 500-8513, Japan.
authors.forename: Michitaka
authors.initials: M
authors.lastname: Kato
authors.affiliation: Department of Diagnostic Pathology, Gifu Municipal Hospital, 7-1 Kashima-cho, Gifu 500-8513, Japan.
authors.forename: Takuji
authors.identifier: 0000-0002-1428-1582
authors.initials: T
authors.lastname: Tanaka
authors.affiliation: Department of Orthopedic Surgery, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
authors.forename: Takatoshi
authors.identifier: 0000-0001-5836-8885
authors.initials: T
authors.lastname: Ohno