title: Enantioselective alkynylation of benzo[e][1,2,3]-oxathiazine 2,2-dioxides catalysed by (R)-VAPOL-Zn complexes: synthesis of chiral propargylic cyclic sulfamidates.
abstract: (R)-VAPOL-Zn(II) complexes catalysed the enantioselective addition of terminal alkynes to cyclic benzoxathiazine 2,2-dioxides, providing the corresponding chiral propargylic sulfamidates with high yields (up to 93%) and good enantiomeric excesses (up to 87%).
authors.affiliation: Departament de Química Orgànica, Facultat de Química, Universitat de València, Dr. Moliner 50, 46100 Burjassot, València, Spain. jose.r.pedro@uv.es.
authors.forename: Lode
authors.initials: L
authors.lastname: De Munck
authors.forename: Alicia
authors.initials: A
authors.lastname: Monleón
authors.forename: Carlos
authors.initials: C
authors.lastname: Vila
authors.forename: M Carmen
authors.initials: MC
authors.lastname: Muñoz
authors.forename: José R
authors.initials: JR
authors.lastname: Pedro
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D002851:Chromatography, High Pressure Liquid; D018360:Crystallography, X-Ray; D008024:Ligands; D010293:Pargyline / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D010616:Phenanthrenes / Q000737:chemistry*; D020005:Propanols; D011437:Propylamines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013843:Thiazines / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D000480:Alkynes; D000577:Amides; D008024:Ligands; D010616:Phenanthrenes; D020005:Propanols; D011437:Propylamines; D013843:Thiazines; C510253:VAPOL ligand; C009054:propargylamine; D010293:Pargyline; D015032:Zinc