title: A case series of 20 women with hidradenitis suppurativa treated with spironolactone.
abstract: Hidradenitis suppurativa (HS) is an uncommon chronic skin condition that can range in severity from a single nodule to extensive disease and can have a profound effect on quality of life. Anti-androgen medication has been suggested as a possible management strategy in female patients with HS and is mentioned in review articles as a treatment option. Despite this, there is limited literature documenting the use of anti-androgens in HS. We present our experience with 20 patients with HS treated with oral spironolactone. We advocate spironolactone as a useful, low-cost first-line treatment for women with HS, with relatively few side-effects.
authors.affiliation: Department of Dermatology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.|Northern Clinical School, University of Sydney, St Leonards, New South Wales, Australia.
authors.forename: Andrew
authors.initials: A
authors.lastname: Lee
authors.affiliation: Department of Dermatology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.|Northern Clinical School, University of Sydney, St Leonards, New South Wales, Australia.
authors.forename: Gayle
authors.initials: G
authors.lastname: Fischer
mesh_terms: D000293:Adolescent; D000328:Adult; D000726:Androgen Antagonists / Q000627:therapeutic use*; D005260:Female; D017497:Hidradenitis Suppurativa / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D013148:Spironolactone / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000726:Androgen Antagonists; D013148:Spironolactone
keywords: anti-androgen; hidradenitis suppurativa; spironolactone