title: Fcγ-receptor tag team boosts anti-tumor immunity.
abstract: Anti-tumor monoclonal antibodies eliminate tumor cells through different mechanisms including antibody-mediated cell cytotoxicity and generation of long-term anti-tumor T cell responses. In a recent publication, DiLillo and Ravetch demonstrate how this vaccinal effect is mediated by engagement of Fcγ receptors expressed on antigen-presenting cells.
authors.affiliation: Cancer Immunology Unit, UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK.
authors.forename: Frederick
authors.initials: F
authors.lastname: Arce Vargas
authors.affiliation: Cancer Immunology Unit, UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6DD, UK. Electronic address: s.quezada@ucl.ac.uk.
authors.forename: Sergio A
authors.initials: SA
authors.lastname: Quezada
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D006801:Humans; D009369:Neoplasms / Q000276:immunology*; D017452:Receptors, IgG / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D017452:Receptors, IgG