title: Effects of indigo carmine intravenous injection on noninvasive and continuous total hemoglobin measurement.
abstract: The effects of an intravenous injection of indigo carmine on noninvasive and continuous total hemoglobin (SpHb) measurement were retrospectively evaluated. The subjects were 21 patients who underwent elective gynecologic surgery under general anesthesia. During surgery, 5 mL of 0.4 % indigo carmine was intravenously injected, and subsequent changes in SpHb concentrations were evaluated. The results demonstrate that the pre-injection SpHb level was 10 g/dL, and the minimum post-injection SpHb level was 8.3 g/dL. The amount of decrease was 1.8 g/dL. The time to reach the minimum value was 4 min, and the time to return to the pre-injection value was 15 min. The decrease in SpHb was greater in the group with a perfusion index (PI) < 1.4 than in the group with a PI > 1.4. The assessment of SpHb after an intravenous injection of indigo carmine necessitates caution.
authors.affiliation: Department of Anesthesiology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, 960-1297, Japan. t-isosu@fmu.ac.jp.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Isosu
authors.affiliation: Department of Anesthesiology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, 960-1297, Japan.
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Satoh
authors.affiliation: Department of Anesthesiology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, 960-1297, Japan.
authors.forename: Rieko
authors.initials: R
authors.lastname: Oishi
authors.affiliation: Department of Anesthesiology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, 960-1297, Japan.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Imaizumi
authors.affiliation: Department of Anesthesiology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, 960-1297, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Hakozaki
authors.affiliation: Department of Anesthesiology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, 960-1297, Japan.
authors.forename: Shinju
authors.initials: S
authors.lastname: Obara
authors.affiliation: Department of Anesthesiology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, 960-1297, Japan.
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Ikegami
authors.affiliation: Department of Anesthesiology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, 960-1297, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Kurosawa
authors.affiliation: Department of Anesthesiology, Fukushima Medical University School of Medicine, 1 Hikariga-oka, Fukushima City, Fukushima, 960-1297, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Murakawa
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D016063:Blood Loss, Surgical; D004396:Coloring Agents / Q000008:administration & dosage*; D017558:Elective Surgical Procedures; D005260:Female; D013509:Gynecologic Surgical Procedures; D006452:Hemoglobinometry / Q000379:methods*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007203:Indigo Carmine / Q000008:administration & dosage*; D007275:Injections, Intravenous; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D012189:Retrospective Studies
chemical_list: D004396:Coloring Agents; D006454:Hemoglobins; D007203:Indigo Carmine
keywords: CO-oximetry; Indigo carmine; Perfusion index; SpHb