title: Severe Tacrolimus-Induced Granulomatous Rosacea Recalcitrant to Oral Tetracyclines.
abstract: Topical tacrolimus has been observed to induce granulomatous rosacea (GR) in prior case reports and series. In most cases, patients recover fully after withdrawing tacrolimus and initiating doxycycline or minocycline. Herein, we describe a case of severe GR, which required further therapy. Clinicians should be aware of this rare complication because of the frequent use of topical tacrolimus.
authors.forename: Lissy
authors.initials: L
authors.lastname: Hu
authors.forename: Christina
authors.initials: C
authors.lastname: Alexander
authors.forename: Nicole F
authors.initials: NF
authors.lastname: Velez
authors.forename: Clarissa
authors.initials: C
authors.lastname: Yang
authors.forename: Alvaro Laga
authors.initials: AL
authors.lastname: Canales
authors.forename: Stephanie
authors.initials: S
authors.lastname: Liu
authors.forename: Ruth Ann
authors.initials: RA
authors.lastname: Vleugels
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003876:Dermatitis, Atopic / Q000188:drug therapy; D005260:Female; D006801:Humans; D012393:Rosacea / Q000139:chemically induced* / Q000188:drug therapy; D016559:Tacrolimus / Q000009:adverse effects* / Q000627:therapeutic use; D013752:Tetracycline / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D013752:Tetracycline; D016559:Tacrolimus