title: Severe Pediatric Adenovirus 7 Disease in Singapore Linked to Recent Outbreaks across Asia.
abstract: During November 2012-July 2013, a marked increase of adenovirus type 7 (Ad7) infections associated with severe disease was documented among pediatric patients in Singapore. Phylogenetic analysis revealed close genetic links with severe Ad7 outbreaks in China, Taiwan, and other parts of Asia.
authors.forename: Oon-Tek
authors.initials: OT
authors.lastname: Ng
authors.forename: Koh Cheng
authors.initials: KC
authors.lastname: Thoon
authors.forename: Hui Ying
authors.initials: HY
authors.lastname: Chua
authors.forename: Natalie Woon Hui
authors.initials: NW
authors.lastname: Tan
authors.forename: Chia Yin
authors.initials: CY
authors.lastname: Chong
authors.forename: Nancy Wen Sim
authors.initials: NW
authors.lastname: Tee
authors.forename: Raymond Tzer Pin
authors.initials: RT
authors.lastname: Lin
authors.forename: Lin
authors.initials: L
authors.lastname: Cui
authors.forename: Indumathi
authors.initials: I
authors.lastname: Venkatachalam
authors.forename: Paul Anantharajah
authors.initials: PA
authors.lastname: Tambyah
authors.forename: Jonathan
authors.initials: J
authors.lastname: Chew
authors.forename: Raymond Kok Choon
authors.initials: RK
authors.lastname: Fong
authors.forename: Helen May Lin
authors.initials: HM
authors.lastname: Oh
authors.forename: Prabha Unny
authors.initials: PU
authors.lastname: Krishnan
authors.forename: Vernon Jian Ming
authors.initials: VJ
authors.lastname: Lee
authors.forename: Boon Huan
authors.initials: BH
authors.lastname: Tan
authors.forename: Sock Hoon
authors.initials: SH
authors.lastname: Ng
authors.forename: Pei Jun
authors.initials: PJ
authors.lastname: Ting
authors.forename: Sebastian
authors.initials: S
authors.lastname: Maurer-Stroh
authors.forename: Vithiagaran
authors.initials: V
authors.lastname: Gunalan
authors.forename: Wei Xin
authors.initials: WX
authors.lastname: Khong
mesh_terms: D000258:Adenovirus Infections, Human / Q000453:epidemiology / Q000473:pathology* / Q000821:virology; D000260:Adenoviruses, Human / Q000235:genetics*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D005814:Genes, Viral; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010802:Phylogeny; D012189:Retrospective Studies; D012846:Singapore / Q000453:epidemiology; D013624:Taiwan / Q000453:epidemiology
keywords: Ad7; Asia; China; Human adenovirus; Malaysia; Singapore; death; invasive disease; mechanical ventilation; outbreak; viruses