title: Oral Diets and Nutrition Support for Inflammatory Bowel Disease: What Is the Evidence?
abstract: Inflammatory bowel disease (IBD), which primarily includes Crohn's disease and ulcerative colitis, involves chronic inflammation of the gastrointestinal tract. The mechanisms of IBD pathogenesis are not well understood at this time, but likely involve an interaction between genetic, gut microbial, immune, and environmental factors. Emerging epidemiologic studies have suggested a relationship between specific dietary nutrients as an environmental factor and IBD risk. Clinical trials have also shown oral diets to have variable efficacy in affecting clinical outcomes for IBD. This review discusses the key studies that evaluated the use of various oral diets as well as nutrition support in the management of IBD.
authors.affiliation: Digestive Health Center, Stanford Health Care, Palo Alto, California Division of Gastroenterology & Hepatology, Stanford University School of Medicine, Stanford, California neshah@stanfordhealthcare.org.
authors.forename: Neha D
authors.initials: ND
authors.lastname: Shah
authors.affiliation: Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Alyssa M
authors.initials: AM
authors.lastname: Parian
authors.affiliation: Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Gerard E
authors.initials: GE
authors.lastname: Mullin
authors.affiliation: Digestive Health Center, Stanford Health Care, Palo Alto, California Division of Gastroenterology & Hepatology, Stanford University School of Medicine, Stanford, California Division of Gastroenterology & Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: Berkeley N
authors.initials: BN
authors.lastname: Limketkai
mesh_terms: D004032:Diet / Q000379:methods*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000178:diet therapy*; D018529:Nutritional Support / Q000379:methods*
keywords: Crohn’s disease; diet fiber; enteral nutrition; gluten; inflammatory bowel diseases; lactose; nutrition therapy; nutritional support; parenteral nutrition; ulcerative colitis