title: Vascular Glucose Sensor Symposium: Continuous Glucose Monitoring Systems (CGMS) for Hospitalized and Ambulatory Patients at Risk for Hyperglycemia, Hypoglycemia, and Glycemic Variability.
abstract: Hyperglycemia, hypoglycemia, and glycemic variability have been associated with increased morbidity, mortality, length of stay, and cost in a variety of critical care and non-critical care patient populations in the hospital. The results from prospective randomized clinical trials designed to determine the risks and benefits of intensive insulin therapy and tight glycemic control have been confusing; and at times conflicting. The limitations of point-of-care blood glucose (BG) monitoring in the hospital highlight the great clinical need for an automated real-time continuous glucose monitoring system (CGMS) that can accurately measure the concentration of glucose every few minutes. Automation and standardization of the glucose measurement process have the potential to significantly improve BG control, clinical outcome, safety and cost.
authors.affiliation: Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA Jeffrey.Joseph@Jefferson.edu.
authors.forename: Jeffrey I
authors.initials: JI
authors.lastname: Joseph
authors.affiliation: Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.
authors.forename: Marc C
authors.initials: MC
authors.lastname: Torjman
authors.affiliation: Capillary Biomedical, Inc., Irvine, CA, USA.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Strasma
mesh_terms: D000465:Algorithms; D000553:Ambulatory Care; D001331:Automation; D001786:Blood Glucose / Q000032:analysis*; D002138:Calibration; D002404:Catheterization; D003920:Diabetes Mellitus / Q000097:blood / Q000175:diagnosis*; D004563:Electrochemistry; D004867:Equipment Design; D006760:Hospitalization; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000175:diagnosis*; D007003:Hypoglycemia / Q000097:blood / Q000175:diagnosis*; D015918:Infusion Pumps, Implantable; D007328:Insulin / Q000627:therapeutic use; D007332:Insulin Infusion Systems; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods; D055100:Optical Fibers; D019095:Point-of-Care Systems; D015203:Reproducibility of Results; D012306:Risk
chemical_list: D001786:Blood Glucose; D007328:Insulin
keywords: artificial pancreas; continuous glucose monitor; continuous glucose monitoring system; glycemic variability; hyperglycemia; hypoglycemia; vascular glucose sensor