title: Controlled Synthesis of Ultrathin Lanthanide Oxide Nanosheets and Their Promising pH-Controlled Anticancer Drug Delivery.
abstract: Various lanthanide oxides (Sm2 O3 and Gd2 O3 ) nanostructures were synthesized by a facile hydrothermal method. The loss of surfactants on the nanocrystals surface, followed by the resultant assembly is responsible for the formation of ultrathin nanosheets. Owing to strong surface effects, the different morphologies of the Sm2 O3 :5 % Eu and Gd2 O3 :5 % Eu nanocrystals present unique photoluminescence properties. As a proof-of-concept application, the as-obtained Sm2 O3 and Gd2 O3 ultrathin nanosheets exhibit promising pH-controlled anticancer drug-delivery behavior.
authors.affiliation: Frontier Institute of Science and Technology jointly with College of Science, State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, 99 Yanxiang Road, Xi'an Shaanxi, 710054 (P. R. China).
authors.forename: Xinyu
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Frontier Institute of Science and Technology jointly with College of Science, State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, 99 Yanxiang Road, Xi'an Shaanxi, 710054 (P. R. China).
authors.forename: Juan
authors.initials: J
authors.lastname: Ge
authors.affiliation: Frontier Institute of Science and Technology jointly with College of Science, State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, 99 Yanxiang Road, Xi'an Shaanxi, 710054 (P. R. China).
authors.forename: Yumeng
authors.initials: Y
authors.lastname: Xue
authors.affiliation: Frontier Institute of Science and Technology jointly with College of Science, State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, 99 Yanxiang Road, Xi'an Shaanxi, 710054 (P. R. China). rayboo@mail.xjtu.edu.cn.
authors.forename: Bo
authors.initials: B
authors.lastname: Lei
authors.affiliation: Frontier Institute of Science and Technology jointly with College of Science, State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, 99 Yanxiang Road, Xi'an Shaanxi, 710054 (P. R. China).
authors.forename: Dong
authors.initials: D
authors.lastname: Yan
authors.affiliation: Frontier Institute of Science and Technology jointly with College of Science, State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, 99 Yanxiang Road, Xi'an Shaanxi, 710054 (P. R. China).
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.affiliation: Frontier Institute of Science and Technology jointly with College of Science, State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, 99 Yanxiang Road, Xi'an Shaanxi, 710054 (P. R. China).
authors.forename: Zhengqing
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Frontier Institute of Science and Technology jointly with College of Science, State Key Laboratory for Mechanical Behavior of Materials, Xi'an Jiaotong University, 99 Yanxiang Road, Xi'an Shaanxi, 710054 (P. R. China). ypdu2013@mail.xjtu.edu.cn, ypdupku@mail.com.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Du
authors.affiliation: School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798 (Singapore).
authors.forename: Ren
authors.initials: R
authors.lastname: Cai
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D016503:Drug Delivery Systems; D005682:Gadolinium / Q000737:chemistry* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D049449:Luminescence; D053758:Nanoparticles / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D010087:Oxides / Q000138:chemical synthesis* / Q000737:chemistry; D010316:Particle Size; D012493:Samarium / Q000737:chemistry; D013499:Surface Properties
chemical_list: D000970:Antineoplastic Agents; D028581:Lanthanoid Series Elements; D010087:Oxides; D012493:Samarium; C030581:gadolinium oxide; C120592:samarium oxide; D005682:Gadolinium
keywords: drug delivery; gadolinium oxide; luminescence; nanostructures; samarium oxide