title: A comparison study of cognitive deficits in radiologically and clinically isolated syndromes.
abstract: Up until now, no information has existed regarding a comparison of the pattern and frequency of cognitive deficits between radiologically isolated syndrome (RIS) and clinically isolated syndrome (CIS) patients. Within this objective, Rao's Brief Repeatable Battery and Stroop test were administered to 28 RIS patients, 25 CIS patients, and 22 healthy controls.
  
  
  CONCLUSIONS
  The prevalence of cognitive deficits in RIS was similar to that of CIS. Cognitive deficits seem to be present in RIS patients regardless of the presence of risk factors for a future symptomatic demyelinating event.
authors.affiliation: Department of Neurology, University Hospital "12 de Octubre", Spain.
authors.forename: Andrés
authors.initials: A
authors.lastname: Labiano-Fontcuberta
authors.affiliation: Department of Neurology, University Hospital "Gregorio Marañón", Spain.
authors.forename: M Luisa
authors.initials: ML
authors.lastname: Martínez-Ginés
authors.affiliation: Department of Neurology, University Hospital of Getafe, Spain.
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Aladro
authors.affiliation: Department of Neurology, University Hospital "Principe de Asturias", Spain.
authors.forename: Lucía
authors.initials: L
authors.lastname: Ayuso
authors.affiliation: Department of Psycho-oncology, Leicestershire Partnership Trust and University of Leicester, UK.
authors.forename: Alex J
authors.initials: AJ
authors.lastname: Mitchell
authors.affiliation: Department of Neurology, University Hospital "12 de Octubre", Spain.
authors.forename: Verónica
authors.initials: V
authors.lastname: Puertas-Martín
authors.affiliation: Department of Neurology, University Hospital of Getafe, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Cerezo
authors.affiliation: Department of Neurology, University Hospital "Gregorio Marañón", Spain.
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Higueras
authors.affiliation: Department of Neurology, University Hospital "12 de Octubre", Spain/Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain/Department of Medicine, Complutense University, Madrid, Spain Jbenitol67@gmail.com.
authors.forename: Julián
authors.initials: J
authors.lastname: Benito-León
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology*; D016022:Case-Control Studies; D003072:Cognition Disorders / Q000473:pathology / Q000523:psychology*; D003711:Demyelinating Diseases / Q000473:pathology / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D013116:Spinal Cord / Q000473:pathology*; D057190:Stroop Test
keywords: Clinically isolated syndrome; cognitive impairment; demyelinating disease; depression; information processing speed; radiologically isolated syndrome