title: Pheomelanin-coated iron oxide magnetic nanoparticles: a promising candidate for negative T2 contrast enhancement in magnetic resonance imaging.
abstract: We describe herein a novel type of monodisperse water-soluble magnetite nanoparticle coated with pheomelanin using an environmentally-friendly approach in aqueous medium. The results indicate superparamagnetic behaviour at room temperature and show improved negative contrast in T2-weighted MRI with a transverse relaxivity of 218 mM(-1) s(-1).
authors.affiliation: Academic Department of Health and Services, Nucleus of Clinical Technology, Instituto Federal de Educação, Ciência e Tecnologia de Santa Catarina, Campus Florianópolis, SC, 88020-300, Brazil. adz@ifsc.edu.br.
authors.forename: Alexandre D A
authors.initials: AD
authors.lastname: Zottis
authors.forename: Jeovandro M
authors.initials: JM
authors.lastname: Beltrame
authors.forename: Luciano R S
authors.initials: LR
authors.lastname: Lara
authors.forename: Thiago G
authors.initials: TG
authors.lastname: Costa
authors.forename: Mateus J
authors.initials: MJ
authors.lastname: Feldhaus
authors.forename: Rozangela Curi
authors.initials: RC
authors.lastname: Pedrosa
authors.forename: Fabiana
authors.initials: F
authors.lastname: Ourique
authors.forename: Carlos E M
authors.initials: CE
authors.lastname: de Campos
authors.forename: Eduardo de A
authors.initials: Ede A
authors.lastname: Isoppo
authors.forename: Fabio
authors.initials: F
authors.lastname: da Silva Miranda
authors.forename: Bruno
authors.initials: B
authors.lastname: Szpoganicz
mesh_terms: D003287:Contrast Media / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D008279:Magnetic Resonance Imaging; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008543:Melanins / Q000737:chemistry*
chemical_list: D003287:Contrast Media; D005290:Ferric Compounds; D058185:Magnetite Nanoparticles; D008543:Melanins; C018362:pheomelanin; C000499:ferric oxide