title: Facial skin physiology recovery kinetics during 180 min post-washing with a cleanser.
abstract: OBJECTIVE
  Facial cleansing is important to clean and exfoliate the skin while maintaining optimal physiologic function. However, there is insufficient data on the very early stage of skin change after applying soap or cleansing foam. We investigated the recovery kinetics of facial skin physiology during 180 min after exposure to the cleanser.
  
  
  METHODS
  For the study, 22 Korean female subjects with normal and dry to oily skin type were recruited in this study. Study subjects were required to have face washing done within the 12 hours prior to visiting the research center, with only toner, lotion, or cream applied. The next day, the subjects visited the research center without face washing. We evaluated the skin hydration (Corneometer(®) CM 825), sebum (Sebumeter(®) SM 815), transepidermal water loss (Tewameter(®) TM 300), and pH (Skin-pH-Meter(®) PH 905) to define recovery kinetics of facial skin physiology during 180 min exposure post-cleansing.
  
  
  RESULTS
  Skin hydration, sebum, and TEWL were significantly decreased at 20 min after washing, as compared to the baseline (P < 0.05). And skin hydration returned at 40 min, and skin sebum and TEWL returned at 120 min after washing. However, skin pH did not show significant differences at all times points.
  
  
  CONCLUSIONS
  This study indicated that each of the skin parameters was restored at defined time points post-cleansing. Our result could be a useful reference to set the resting time in the estimation of skin bioengineering parameters.
authors.affiliation: Dermapro Skin Research Center, DERMAPRO LTD, Seoul, Korea.
authors.forename: J
authors.initials: J
authors.lastname: Eo
authors.affiliation: Dermapro Skin Research Center, DERMAPRO LTD, Seoul, Korea.
authors.forename: Y K
authors.initials: YK
authors.lastname: Seo
authors.affiliation: Dermapro Skin Research Center, DERMAPRO LTD, Seoul, Korea.
authors.forename: J H
authors.initials: JH
authors.lastname: Baek
authors.affiliation: Dermapro Skin Research Center, DERMAPRO LTD, Seoul, Korea.
authors.forename: A R
authors.initials: AR
authors.lastname: Choi
authors.affiliation: Dermapro Skin Research Center, DERMAPRO LTD, Seoul, Korea.|Department of Dermatology, School of medicine, Kyung Hee University, Seoul, Korea.
authors.forename: M K
authors.initials: MK
authors.lastname: Shin
authors.affiliation: Dermapro Skin Research Center, DERMAPRO LTD, Seoul, Korea.
authors.forename: J S
authors.initials: JS
authors.lastname: Koh
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D003879:Dermatologic Agents / Q000008:administration & dosage*; D003902:Detergents / Q000008:administration & dosage*; D005145:Face / Q000502:physiology*; D005260:Female; D006801:Humans; D007700:Kinetics; D008875:Middle Aged; D020127:Recovery of Function / Q000187:drug effects / Q000502:physiology*; D012869:Skin Absorption / Q000187:drug effects / Q000502:physiology*; D017592:Skin Care / Q000379:methods; D012879:Skin Physiological Phenomena / Q000187:drug effects; D013997:Time Factors; D014870:Water Loss, Insensible / Q000187:drug effects / Q000502:physiology*; D055815:Young Adult
chemical_list: D003879:Dermatologic Agents; D003902:Detergents
keywords: facial cleansing; facial skin physiology; resting time