title: Clinical research on intelligence seven needle therapy treated infants with brain damage syndrome.
abstract: OBJECTIVE
  To assess whether the intelligence seven needle therapy administered in infants with perinatal brain damage syndrome (BDS) as early intervention would improve patients' neural development.
  
  
  METHODS
  A randomized controlled trial was conducted. Sixty-four infants with BDS were randomly assigned to two groups: the comprehensive group and the control group. Both groups received routine early intervention; in addition, the comprehensive group received intelligence seven needle therapy. Before and after treatment, the Bayley Scale of Infant Development (BSID), Gesell Developmental Schedules, Gross Motor Function Measure (GMFM), transcranial doppler ultrasound (TCD), and cranial imaging examination were tested for contrast.
  
  
  RESULTS
  After treatment, the comprehensive group showed significant difference in the Mental Development Index (MDI) scores of BSID compared with the control group (P<0.05), however, no significant discrepancy in psychomotor development index (PDI,P>0.05) was observed. The children's development quotients (DQ) of the comprehensive group exhibited a significant superiority in improving the social adaptation DQ of Gesell Developmental Schedules compared with the control group (P<0.01), as well as GMFM and linguistic and social intercourse (P<0.05). Again, no discrepancy in the fine movement DQ was found (P>0.05). The total scores of GMFM in the comprehensive group were higher than those in the control group (P<0.05). Comparing the two groups, the comprehensive group showed a significantly greater recovery rate than the control group on TCD after treatment (P<0.05). After 6-month follow-up, some recovery in both groups, specifically on broadening of brain outside space by cranial imaging examination were observed. The comprehensive group demonstrated a significantly greater recovery rate than the control group (P<0.05).
  
  
  CONCLUSIONS
  The developmental level of intelligence, motion function, linguistic competence and social intercourse can be promoted for infants with perinatal BDS by treating with the intelligence seven needle therapy. This approach can improve the brain blood supply and promote the growth of frontal and parietal lobes.
authors.affiliation: Cerebral Palsy Rehabilitation Center of Nanhai Maternity and Children Hospital Affiliated to Guangzhou University of Chinese Medicine, Foshan, Guangdong Province, 528200, China. lzh1958424@163.com.
authors.forename: Zhen-Huan
authors.initials: ZH
authors.lastname: Liu
authors.affiliation: Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
authors.forename: Ye-Rong
authors.initials: YR
authors.lastname: Li
authors.affiliation: Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
authors.forename: Yong-Lin
authors.initials: YL
authors.lastname: Lu
authors.affiliation: Sanya Traditional Chinese Medicine Hospital, Sanya, Hainan Province, 572000, China.
authors.forename: Jie-Kui
authors.initials: JK
authors.lastname: Chen
mesh_terms: D015670:Acupuncture Therapy; D001930:Brain Injuries / Q000000981:diagnostic imaging / Q000628:therapy*; D002657:Child Development; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007360:Intelligence; D008279:Magnetic Resonance Imaging; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D017585:Ultrasonography, Doppler, Transcranial
keywords: acupuncture; brain damage syndrome; early intervention; intelligence seven needle therapy