title: Dual Diagnostic Role of 123I-MIBG Scintigraphy in Inverted-Takotsubo Pattern Cardiomyopathy.
abstract: We highlight the dual role of I-MIBG scintigraphy in inverted-Takotsubo pattern cardiomyopathy, the diagnosis of which is sometimes challenging: Firstly, I-MIBG scintigraphy can show myocardial sympathetic dysfunction (low I-MIBG uptake) in the hypokinetic basal segments, sparing the left ventricle apex. It is helpful in the imaging diagnosis of inverted-Takotsubo pattern cardiomyopathy and confirms that acute dysfunction of myocardial sympathetic nerve endings occurs with this cardiomyopathy. Secondly, I-MIBG scintigraphy is an accurate imaging examination to detect and localize pheochromocytoma; it can help in the search for an endogenous cause of this adrenergic stress-related cardiomyopathy.
authors.affiliation: From the *Imaging Department, CHU, Dijon, France; †Nuclear Medicine Department, Centre GF Leclerc, Dijon, France; ‡Université de Bourgogne, UMR CNRS 6306, Dijon, France; §Cardiology Department, CHU, Dijon, France; and ∥LPPCM, UMR INSERM 866, Dijon, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Humbert
authors.forename: Karim
authors.initials: K
authors.lastname: Stamboul
authors.forename: Aurélie
authors.initials: A
authors.lastname: Gudjoncik
authors.forename: Salim
authors.initials: S
authors.lastname: Kanoun
authors.forename: Carole
authors.initials: C
authors.lastname: Richard
authors.forename: Alexandre
authors.initials: A
authors.lastname: Cochet
authors.forename: Yves
authors.initials: Y
authors.lastname: Cottin
mesh_terms: D019797:3-Iodobenzylguanidine; D000328:Adult; D006801:Humans; D008297:Male; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D054549:Takotsubo Cardiomyopathy / Q000000981:diagnostic imaging*
chemical_list: D019275:Radiopharmaceuticals; D019797:3-Iodobenzylguanidine