title: Evaluation of Infectious Complications in the First Year After Kidney Transplantation.
abstract: Kidney transplantation (KT) is the best available therapy for patients with end-stage renal disease. Infectious complications are a common cause of morbidity and mortality. In this study, we evaluated the risk factors and outcomes of infectious complications in the first year after transplantation. This is a retrospective and observational study of kidney transplant recipients at Ankara University's Ibni Sina Hospital between January 2009 and August 2013. A total of 206 kidney transplant recipients were evaluated. In 129 patients, 298 infectious episodes occurred: 55 (26.7%) had 1; 33 (16%) 2; 19 (9.2%) 3; 7 (3.4%) 4; and 15 (7.3%) had 5 or more infectious episodes. The most common bacterial infection was urinary tract infection (128, 42.9%). Only 4 urinary tract infection episodes (3.1%) were associated with bacteriemia. Seventeen patients (5.7%) had bacteremia. Viral infections after transplantation were CMV infection (10.1%), BK virus infection (5.7%), and zona zoster (1.1%). Deceased donor kidney transplantation was the independent risk factor. Mean follow-up period was 66 months and was the same for the patients with and without infections. There was no significant difference in 5-year survival and creatinine levels at the last follow-up (logrank P = .409). Infections are the second most common cause of mortality in KT patients. The successful treatment of these complications and effective prophylaxis may decrease these complications.
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Ankara University Faculty of Medicine, Ankara, Turkey. Electronic address: aky1976@hotmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Yalci
authors.affiliation: Department of Nephrology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: Z K
authors.initials: ZK
authors.lastname: Celebi
authors.affiliation: Department of Internal Medicine, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Ozbas
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: O L
authors.initials: OL
authors.lastname: Sengezer
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Unal
authors.affiliation: Department of Infectious Diseases and Clinical Microbiology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: K O
authors.initials: KO
authors.lastname: Memikoğlu
authors.affiliation: Department of Nephrology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Sengul
authors.affiliation: Department of General Surgery, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Tuzuner
authors.affiliation: Department of Nephrology, Ankara University Faculty of Medicine, Ankara, Turkey.
authors.forename: K
authors.initials: K
authors.lastname: Keven
mesh_terms: D000328:Adult; D001739:BK Virus; D016470:Bacteremia / Q000209:etiology; D001424:Bacterial Infections / Q000209:etiology; D003141:Communicable Diseases / Q000209:etiology / Q000401:mortality*; D003404:Creatinine / Q000097:blood; D003586:Cytomegalovirus Infections / Q000821:virology; D005260:Female; D005500:Follow-Up Studies; D006562:Herpes Zoster; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000401:mortality; D016030:Kidney Transplantation / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D027601:Polyomavirus Infections / Q000821:virology; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis; D014412:Tumor Virus Infections / Q000821:virology; D014552:Urinary Tract Infections / Q000209:etiology
chemical_list: D003404:Creatinine