title: Metastatic Uterine Leiomyosarcoma Involving Bilateral Ovarian Stroma without Capsular Involvement Implies a Local Route of Hematogenous Dissemination.
abstract: Uterine sarcomas spread via lymphatic and hematogenous dissemination, direct extension, or transtubal transport. Distant metastasis often involves the lungs. Ovarian metastasis is uncommon. Here we present an unusual case of a large, high-grade uLMS with metastatic disease internal to both ovaries without capsular involvement or other abdominal diseases, and discovered in a patient with distant metastases to the lungs, suggesting likely hematogenous dissemination of uLMS to the ovaries in this case. Knowledge of usual uLMS metastases may influence surgical management in select cases.
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Biology, Western Connecticut Health Network, 24 Hospital Avenue, Danbury, CT 06810, USA.
authors.forename: Monica
authors.initials: M
authors.lastname: Dandapani
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Biology, Western Connecticut Health Network, 24 Hospital Avenue, Danbury, CT 06810, USA.
authors.forename: Brandon-Luke L
authors.initials: BL
authors.lastname: Seagle
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Biology, Western Connecticut Health Network, 24 Hospital Avenue, Danbury, CT 06810, USA.
authors.forename: Amer
authors.identifier: 0000-0002-2203-7854
authors.initials: A
authors.lastname: Abdullah
authors.affiliation: Department of Pathology, Western Connecticut Health Network, 24 Hospital Avenue, Danbury, CT 06810, USA.
authors.forename: Bryce
authors.initials: B
authors.lastname: Hatfield
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Biology, Western Connecticut Health Network, 24 Hospital Avenue, Danbury, CT 06810, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Samuelson
authors.affiliation: Division of Gynecologic Oncology, Northwestern University Feinberg School of Medicine, 250 East Superior Street, Suite 03-2303, Chicago, IL 60611, USA.
authors.forename: Shohreh
authors.identifier: 0000-0001-5091-2954
authors.initials: S
authors.lastname: Shahabi