title: Community-acquired infections due to Staphylococcus argenteus lineage isolates harbouring the Panton-Valentine leucocidin, France, 2014.
abstract: We describe two cases of human infections caused by Staphylococcus aureus clonal complex (CC) 75, also called Staphylococcus argenteus, harbouring the Panton-Valentine leucocidin (PVL). These two sporadic cases were community-acquired, and identified in France in 2014. Both had an epidemiological link with Mayotte, an overseas department of France located in the Indian Ocean off the south-eastern African coast. This report illustrates that, contrary to previous descriptions, S. argenteus can acquire important virulence factors and be responsible for severe infections.
authors.affiliation: Centre National de Reference des Staphylocoques, Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, Bron, France.
authors.forename: C
authors.initials: C
authors.lastname: Dupieux
authors.forename: R
authors.initials: R
authors.lastname: Blondé
authors.forename: C
authors.initials: C
authors.lastname: Bouchiat
authors.forename: H
authors.initials: H
authors.lastname: Meugnier
authors.forename: M
authors.initials: M
authors.lastname: Bes
authors.forename: S
authors.initials: S
authors.lastname: Laurent
authors.forename: F
authors.initials: F
authors.lastname: Vandenesch
authors.forename: F
authors.initials: F
authors.lastname: Laurent
authors.forename: A
authors.initials: A
authors.lastname: Tristan
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001427:Bacterial Toxins / Q000235:genetics; D017714:Community-Acquired Infections; D017507:Comoros; D005098:Exotoxins / Q000235:genetics; D005260:Female; D005602:France; D006801:Humans; D007223:Infant; D007956:Leukocidins / Q000235:genetics; D008297:Male; D016133:Polymerase Chain Reaction; D013203:Staphylococcal Infections / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D013210:Staphylococcus / Q000187:drug effects; D013211:Staphylococcus aureus / Q000145:classification / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin