title: Iron(III)-Selective Chelation-Enhanced Fluorescence Sensing for In Vivo Imaging Applications.
abstract: A "turn-on" pattern Fe(3+) -selective fluorescent sensor was synthesized and characterized that showed high fluorescence discrimination of Fe(3+) over Fe(2+) and other tested ions. With a 62-fold fluorescence enhancement towards Fe(3+) , the probe was employed to detect Fe(3+) in vivo in HeLa cells and Caenorhabditis elegans, and it was also successfully used to elucidate Fe(3+) enrichment and exchange infected by innexin3 (Inx3) in hemichannel-closed Sf9 cells.
authors.affiliation: College of Chemical Science and Technology, Yunnan University, Kunming, 650091, China.
authors.forename: Lin E
authors.initials: LE
authors.lastname: Guo
authors.affiliation: College of Life Science, Yunnan University, Kunming, 650091, China.
authors.forename: Xin Yi
authors.initials: XY
authors.lastname: Liu
authors.affiliation: College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, 650500, China.
authors.forename: Huan
authors.initials: H
authors.lastname: Wang
authors.affiliation: College of Chemical Science and Technology, Yunnan University, Kunming, 650091, China.
authors.forename: Qiu Ling
authors.initials: QL
authors.lastname: Chen
authors.affiliation: College of Chemical Science and Technology, Yunnan University, Kunming, 650091, China.
authors.forename: Guang Ke
authors.initials: GK
authors.lastname: Wang
authors.affiliation: College of Life Science, Yunnan University, Kunming, 650091, China.
authors.forename: Kaijun
authors.initials: K
authors.lastname: Luo
authors.affiliation: Yunnan Institute of Microbiology, Yunnan University, Kunming, 650091, China.|Technology Center, China Tobacco Yunnan Industrial Co., Ltd, Kunming, 650231, China.
authors.forename: Qi Li
authors.initials: QL
authors.lastname: Mi
authors.affiliation: College of Chemical Science and Technology, Yunnan University, Kunming, 650091, China. yingzhou@ynu.edu.cn.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, 650500, China. junfengzhang78@aliyun.com.
authors.forename: Jun Feng
authors.initials: JF
authors.lastname: Zhang
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000737:chemistry / Q000648:ultrastructure; D002460:Cell Line; D005260:Female; D005290:Ferric Compounds / Q000032:analysis*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D007502:Iron Chelating Agents / Q000737:chemistry*; D008856:Microscopy, Fluorescence; D061848:Optical Imaging; D010053:Ovary / Q000166:cytology; D013050:Spectrometry, Fluorescence; D018411:Spodoptera / Q000166:cytology
chemical_list: D005290:Ferric Compounds; D005456:Fluorescent Dyes; D007502:Iron Chelating Agents
keywords: dyes/pigments; fluorescence; fluorescent probes; iron; sensors