title: Explicit Filtering Based Low-Dose Differential Phase Reconstruction Algorithm with the Grating Interferometry.
abstract: X-ray grating interferometry offers a novel framework for the study of weakly absorbing samples. Three kinds of information, that is, the attenuation, differential phase contrast (DPC), and dark-field images, can be obtained after a single scanning, providing additional and complementary information to the conventional attenuation image. Phase shifts of X-rays are measured by the DPC method; hence, DPC-CT reconstructs refraction indexes rather than attenuation coefficients. In this work, we propose an explicit filtering based low-dose differential phase reconstruction algorithm, which enables reconstruction from reduced scanning without artifacts. The algorithm adopts a differential algebraic reconstruction technique (DART) with the explicit filtering based sparse regularization rather than the commonly used total variation (TV) method. Both the numerical simulation and the biological sample experiment demonstrate the feasibility of the proposed algorithm.
authors.affiliation: Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing 100084, China ; Department of Engineering Physics, Tsinghua University, Beijing 100084, China.
authors.forename: Xiaolei
authors.identifier: 0000-0001-7995-8059
authors.initials: X
authors.lastname: Jiang
authors.affiliation: Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing 100084, China ; Department of Engineering Physics, Tsinghua University, Beijing 100084, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Particle & Radiation Imaging (Tsinghua University), Ministry of Education, Beijing 100084, China ; Department of Engineering Physics, Tsinghua University, Beijing 100084, China.
authors.forename: Ran
authors.initials: R
authors.lastname: Zhang
authors.affiliation: Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.
authors.forename: Hongxia
authors.initials: H
authors.lastname: Yin
authors.affiliation: Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Zhenchang
authors.initials: Z
authors.lastname: Wang
mesh_terms: D000465:Algorithms; D000818:Animals; D019295:Computational Biology; D005123:Eye / Q000033:anatomy & histology; D006168:Guinea Pigs; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods* / Q000706:statistics & numerical data; D007368:Interferometry / Q000379:methods* / Q000706:statistics & numerical data; D008953:Models, Anatomic; D019047:Phantoms, Imaging; D014965:X-Rays