title: [Application of CT and MRI in the Diagnosis of Paragonimiasis in Brain and Spinal Cord].
abstract: Clinical data of 22 cases with paragonimiasis in brain and spinal cord in the Central Hospital of Enshi Tujia and Miao Autonomous Prefecture during 2003 -2012 were retrospectively analyzed. Twenty-two cases aged from 6 to 17 years old, including 15 males and 7 females, were from the countryside, and had a history of eating raw crabs. CT and MRI showed that all the cases had cerebral lesion, 16 cases had unilateral lesion of cerebral hemisphere, and 6 cases had bilateral hemisphere lesions. There were mainly two kinds of imaging changes: (1) the infarct and low- density edema of large area with focal hemorrhage; (2) annular lesions. Among the 6 cases with intracerebral hematoma, 2 patients received surgical removal, and all the patients were treated with praziquantel, 25 mg/kg each time, 3 times per day, 3 d for a course. This regimen was repeated at a 7-day interval. All the patients were cured and discharged from hospital.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Li
authors.forename: Da-ming
authors.initials: DM
authors.lastname: Qin
mesh_terms: D000293:Adolescent; D001921:Brain / Q000469:parasitology* / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010237:Paragonimiasis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D011223:Praziquantel / Q000627:therapeutic use; D012189:Retrospective Studies; D013116:Spinal Cord / Q000469:parasitology*; D014057:Tomography, X-Ray Computed
chemical_list: D011223:Praziquantel