title: Autosomal dominant polycystic kidney disease (ADPKD) is associated with coronary arterial dilatation in end-stage renal failure patients.
abstract: Autosomal dominant polycystic kidney disease (ADPKD) can affect several organs in addition to the kidney. There is paucity in the literature on the cardiac manifestations of this disease. This retrospective study aimed to assess whether ADPKD was associated with a larger coronary artery diameter and to evaluate for the presence of coronary artery aneurysm and ectasia. This study shows that subjects with ADPKD and end-stage renal failure have dilatation of coronary arteries independent of traditional coronary risk factors and medication use.
authors.affiliation: Department of Cardiology, Westmead Hospital, Sydney, Australia ; Faculty of Medicine, University of Sydney, Sydney, Australia.
authors.forename: Joseph
authors.initials: J
authors.lastname: Chiha
authors.affiliation: Centre for Transplant and Renal Research, Westmead Millennium Institute, University of Sydney at Westmead Hospital, Sydney, Australia.
authors.forename: Gopala K
authors.initials: GK
authors.lastname: Rangan
authors.affiliation: Centre for Transplant and Renal Research, Westmead Millennium Institute, University of Sydney at Westmead Hospital, Sydney, Australia.
authors.forename: Jeremy R
authors.initials: JR
authors.lastname: Chapman
authors.affiliation: Department of Cardiology, Westmead Hospital, Sydney, Australia ; Faculty of Medicine, University of Sydney, Sydney, Australia.
authors.forename: Aravinda
authors.initials: A
authors.lastname: Thiagalingam
keywords: autosomal dominant polycystic kidney disease; coronary angiogram; coronary artery size