title: Image-guided drug delivery: preclinical applications and clinical translation.
abstract: Image-guided drug delivery refers to the combination of drug targeting and imaging. Preclinically, image-guided drug delivery can be used for several different purposes, including for monitoring biodistribution, target site accumulation, off-target localization, drug release and drug efficacy. Clinically, it holds significant potential for preselecting patients. In this editorial, we briefly summarize the main principles of image-guided drug delivery, and we describe its potential for facilitating, furthering and personalizing nanomedicine treatments.
authors.affiliation: RWTH Aachen University, University Clinic and Helmholtz Institute for Biomedical Engineering, Institute for Experimental Molecular Imaging (ExMI), Department of Nanomedicines and Theranostics , Pauwelsstrasse 30, 52074 Aachen , Germany.
authors.forename: Tarun
authors.initials: T
authors.lastname: Ojha
authors.forename: Larissa
authors.initials: L
authors.lastname: Rizzo
authors.forename: Gert
authors.initials: G
authors.lastname: Storm
authors.forename: Fabian
authors.initials: F
authors.lastname: Kiessling
authors.forename: Twan
authors.initials: T
authors.lastname: Lammers
mesh_terms: D000818:Animals; D003952:Diagnostic Imaging / Q000379:methods*; D016503:Drug Delivery Systems / Q000379:methods*; D065546:Drug Liberation; D006801:Humans; D050997:Nanomedicine / Q000379:methods*; D014018:Tissue Distribution
keywords: drug delivery; imaging; nanomedicine; theranostics