title: The Relationship Between Epicardial Adipose Tissue Thickness and Infarct-Related Artery Patency in Patients With ST-Segment Elevation Myocardial Infarction.
abstract: We investigated the relationship between epicardial adipose tissue (EAT) and infarct-related artery (IRA) patency before mechanical reperfusion in patients with ST-segment elevation myocardial infarction (STEMI). Patients (n = 640) were divided into 2 groups based on the thrombolysis in myocardial infarction (TIMI) flow grade. Impaired flow was defined as TIMI grades 0, 1, and 2, and normal flow was defined as TIMI 3. On the admission angiography, 65 (10.2%) patients had TIMI 3 flow, and the remaining 575 (89.8%) had TIMI 0, 1, or 2 flow. The impaired flow group patients had a higher incidence of diabetes mellitus (53.7% vs 41.5%, P = .035), higher EAT thickness (5.66 ± 1.84 vs 4.87 ± 2.09 mm, P = .001), and lower ejection fraction (43.1% ± 8.9% vs 47.4% ± 9.1%, P = .025). Multivariate stepwise logistic regression analysis showed that IRA patency was independently associated with EAT thickness (odds ratio [OR] 0.785; 95% confidence interval [CI] 0.712-0.858; P = .001) and neutrophil-lymphocyte ratio (OR 0.815; 95% CI 0.732-0.917; P = .025). Thickness of EAT was an independent predictor of lower TIMI flow in IRA in patients with STEMI.
authors.affiliation: Cardiology clinic, Turkey Yuksek Ihtisas Education and Research Hospital, Sihhiye, Ankara, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Sen
authors.affiliation: Cardiology clinic, Turkey Yuksek Ihtisas Education and Research Hospital, Sihhiye, Ankara, Turkey sametyilmazmd@gmail.com.
authors.forename: Samet
authors.initials: S
authors.lastname: Yilmaz
authors.affiliation: Cardiology clinic, Turkey Yuksek Ihtisas Education and Research Hospital, Sihhiye, Ankara, Turkey.
authors.forename: Kevser Gülcihan
authors.initials: KG
authors.lastname: Balci
authors.affiliation: Cardiology clinic, Van Erciş State Hospital, Van, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Gül
authors.affiliation: Cardiology clinic, Turkey Yuksek Ihtisas Education and Research Hospital, Sihhiye, Ankara, Turkey.
authors.forename: Mustafa Mücahit
authors.initials: MM
authors.lastname: Balci
authors.affiliation: Cardiology clinic, Turkey Yuksek Ihtisas Education and Research Hospital, Sihhiye, Ankara, Turkey.
authors.forename: Mehmet Kadri
authors.initials: MK
authors.lastname: Akboga
authors.affiliation: Cardiology clinic, Turkey Yuksek Ihtisas Education and Research Hospital, Sihhiye, Ankara, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Topaloglu
authors.affiliation: Cardiology clinic, Turkey Yuksek Ihtisas Education and Research Hospital, Sihhiye, Ankara, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Temizhan
authors.affiliation: Cardiology clinic, Turkey Yuksek Ihtisas Education and Research Hospital, Sihhiye, Ankara, Turkey.
authors.forename: Dursun
authors.initials: D
authors.lastname: Aras
authors.affiliation: Cardiology clinic, Turkey Yuksek Ihtisas Education and Research Hospital, Sihhiye, Ankara, Turkey.
authors.forename: Sinan
authors.initials: S
authors.lastname: Aydogdu
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging*; D000328:Adult; D015906:Angioplasty, Balloon, Coronary; D016009:Chi-Square Distribution; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006801:Humans; D016015:Logistic Models; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy; D009504:Neutrophils; D016017:Odds Ratio; D010496:Pericardium / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D012307:Risk Factors; D016896:Treatment Outcome; D014654:Vascular Patency
keywords: acute coronary syndrome; epicardial adipose tissue thickness; infarct-related artery