title: Accurate Characterization of Skeletal Lesions in Tuberous Sclerosis Complex Using 99mTc MDP SPECT/CT.
abstract: We report a 15-year-old patient with tuberous sclerosis complex or Bourneville's disease with history of generalized tonic-clonic seizure for last 2 years and was currently on antiepileptic medication. He also had a history of left nephrectomy for renal cell carcinoma clear cell type. The patient had multiple adenoma sebaceum over the nasolabial region, ash leaf spots over the lower limbs, a Shagreen patch over the back, and multiple calcified tubers in the subependymal region. He was then referred for the skeletal scintigraphy to look for skeletal lesions, which revealed involvement of bilateral humeri, tibiae, and iliac bones accurately characterized on SPECT/CT.
authors.affiliation: From the Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Girish Kumar
authors.initials: GK
authors.lastname: Parida
authors.forename: Varun Singh
authors.initials: VS
authors.lastname: Dhull
authors.forename: Sellam
authors.initials: S
authors.lastname: Karunanithi
authors.forename: Saurabh
authors.initials: S
authors.lastname: Arora
authors.forename: Anshul
authors.initials: A
authors.lastname: Sharma
authors.forename: Shamim Ahmed
authors.initials: SA
authors.lastname: Shamim
mesh_terms: D000293:Adolescent; D001842:Bone and Bones / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed; D014402:Tuberous Sclerosis / Q000000981:diagnostic imaging*
chemical_list: D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate