title: Synthesis and Application of [3.3.0]Furofuranone in Total Synthesis.
abstract: The synthesis and application of [3.3.0]furofuranone species has received considerable attention from the scientific community. During the last twenty years, there has been a remarkable increase in publications focusing on their relevant method development as well as applications to natural product synthesis. This tutorial review discusses instructive examples to give a special emphasis on the development of new synthetic approaches and important applications to the total synthesis of natural products.
authors.affiliation: Department of Chemistry, State Key Laboratory of Synthetic Chemistry, Center of Novel Functional Molecules, and Institute of Molecular Functional Materials, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China), Fax: (+852) 26035315. xspeng@cuhk.edu.hk.|Shenzhen Center of Novel Functional Molecules, Shenzhen Research Institute, and Shenzhen Municipal Key Laboratory of Chemical Synthesis of Medicinal Organic Molecules, The Chinese University of Hong Kong, No.10, Second Yuexing Road, Shenzhen, 518507, China. xspeng@cuhk.edu.hk.
authors.forename: Xiao-Shui
authors.initials: XS
authors.lastname: Peng
authors.affiliation: Department of Chemistry, State Key Laboratory of Synthetic Chemistry, Center of Novel Functional Molecules, and Institute of Molecular Functional Materials, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China), Fax: (+852) 26035315.
authors.forename: Ridge Michael P
authors.initials: RM
authors.lastname: Ylagan
authors.affiliation: Department of Chemistry, State Key Laboratory of Synthetic Chemistry, Center of Novel Functional Molecules, and Institute of Molecular Functional Materials, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China), Fax: (+852) 26035315.
authors.forename: Yuk Ming
authors.initials: YM
authors.lastname: Siu
authors.affiliation: Department of Chemistry, State Key Laboratory of Synthetic Chemistry, Center of Novel Functional Molecules, and Institute of Molecular Functional Materials, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China), Fax: (+852) 26035315. hncwong@cuhk.edu.hk.|Shenzhen Center of Novel Functional Molecules, Shenzhen Research Institute, and Shenzhen Municipal Key Laboratory of Chemical Synthesis of Medicinal Organic Molecules, The Chinese University of Hong Kong, No.10, Second Yuexing Road, Shenzhen, 518507, China. hncwong@cuhk.edu.hk.
authors.forename: Henry N C
authors.initials: HN
authors.lastname: Wong
mesh_terms: D001688:Biological Products / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic / Q000379:methods; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D015394:Molecular Structure; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D001688:Biological Products; D006571:Heterocyclic Compounds; D004364:Pharmaceutical Preparations
keywords: domino reactions; furofuranones; natural products; synthesis; total synthesis