title: [Usefulness of gastric emptying scintigraphy for the evaluation and management of scleroderma related gastroparesis].
abstract: Scleroderma is a chronic autoimmune disease of unknown cause characterized by fibrotic skin and multiple organs involvement, including the gastrointestinal tract. It occurs mainly in women between 35 and 65 years of age. It is classified as limited or diffuse based on the extent of skin involvement. Gastrointestinal dysmotility is observed in up to 90% of patients with a diffuse and limited scleroderma. It may involve any segment of the gastrointestinal tract from the esophagus to the anus and is related to collagen deposition at the level of enteric and vascular smooth muscle. Gastroparesis is a condition characterized by abnormal gastric motility, delay gastric emptying, in the absence of a mechanical obstruction to outflow. Gastric scintigraphy with radiolabeled solid food is the gold standard for the diagnosis of gastroparesis. Two cases of patients with systemic scleroderma and severe gastroparesis are presented in order to discuss the diagnostic and therapeutic approach, emphasizing the utility of gastric emptying scintigraphy.
authors.forename: María M
authors.initials: MM
authors.lastname: Piskorz
authors.forename: Gerardo
authors.initials: G
authors.lastname: Rank
authors.forename: María
authors.initials: M
authors.lastname: Velázquez Espeche
authors.forename: Analisa
authors.initials: A
authors.lastname: García Cainzo
authors.forename: Andrea
authors.initials: A
authors.lastname: Pisarevsky
authors.forename: Juan A
authors.initials: JA
authors.lastname: Sorda
authors.forename: Jorge
authors.initials: J
authors.lastname: Olmos
mesh_terms: D000368:Aged; D005260:Female; D005746:Gastric Emptying / Q000502:physiology*; D018589:Gastroparesis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D011877:Radionuclide Imaging; D015203:Reproducibility of Results; D045743:Scleroderma, Diffuse / Q000150:complications* / Q000503:physiopathology; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index