title: Recurrent Glioblastoma Multiforme (grade IV - WHO 2007): a case of complete objective response - concomitant administration of Somatostatin / Octreotide, Retinoids, Vit E, Vit D3, Vit C, Melatonin, D2 R agonists (Di Bella Method.
abstract: In a 41 year old man, with Glioblastoma Multiforme (Grade IV - WHO 2007) and loco-regional recurrence, treated conventionally with surgery, radio-therapy and Temolozomide, a complete objective response was subsequently achieved by means of the well-tolerated concomitant administration of Somatostatin + slow-release Octreotide, Melatonin, Retinoids solubilized in Vitamin E, Vit D3, Vit C, D2 R agonists, and Temolozomide. In addition to the positive and previously unreported therapeutic finding, this result allowed the patient to avoid further surgical trauma and the correlated risks, achieving an excellent quality of life and working capacity.
authors.affiliation: Di Bella Foundation, Bologna, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Di Bella
authors.affiliation: Di Bella Foundation, Bologna, Italy.
authors.forename: Jovan
authors.initials: J
authors.lastname: Leci
authors.affiliation: Di Bella Foundation, Bologna, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Ricchi
authors.affiliation: Di Bella Foundation, Bologna, Italy.
authors.forename: Rosilde
authors.initials: R
authors.lastname: Toscano
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D005909:Glioblastoma / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D008297:Male; D060787:Neoplasm Grading; D009364:Neoplasm Recurrence, Local; D015173:Supratentorial Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000601:surgery