title: Peri-anaesthetic complications in an equine referral hospital: Risk factors for post anaesthetic colic.
abstract: BACKGROUND
  Peri-anaesthetic complications are relatively common in equine patients and further investigations are warranted to identify manageable risk factors.
  
  
  OBJECTIVE
  To report morbidity and mortality rates and identify associated risk factors for horses undergoing general anaesthesia, within a predominantly racing Thoroughbred (TB) population.
  
  
  METHODS
  Single centre retrospective observational study.
  
  
  METHODS
  Anaesthetic and case records of all horses ≥12 months old undergoing general anaesthesia at Newmarket Equine Hospital between August 2010 and April 2012 were analysed, excluding emergency abdominal/dystocia procedures or traumatology cases with cardiovascular compromise. Mortality and morbidity rates were calculated and described. Uni- and multivariable analyses were used to investigate the relationship between the principal complication, post anaesthetic colic (PAC) and risk factors.
  
  
  RESULTS
  A total of 1067 anaesthetic records of 1021 horses were included in the study; of these, 702 horses (65.8%) were TB, 169 (15.8%) developed a complication within 7 days of general anaesthesia and 10 (0.94%) died as a result. The most prevalent morbidity was PAC, 111 horses (10.5%) developed colic within 7 days of general anaesthesia. Thoroughbred horses (odds ratio [OR] 2.93, 95% confidence interval [CI] 1.73-4.96) and horses receiving sodium benzylpenicillin (NaBP) (OR 2.77, 95% CI 1.69-4.50) were at increased risk of PAC.
  
  
  CONCLUSIONS
  Thoroughbred racehorses were identified as at increased risk of PAC in this study and might benefit from more critical evaluation of post anaesthetic gastrointestinal function. An alternative to the administration of NaBP for prophylactic antimicrobial therapy needs to be further investigated if its role in PAC is confirmed by other studies.
authors.affiliation: Newmarket Equine Hospital, Suffolk, UK.
authors.forename: R C
authors.initials: RC
authors.lastname: Jago
authors.affiliation: Newmarket Equine Hospital, Suffolk, UK.
authors.forename: F
authors.initials: F
authors.lastname: Corletto
authors.affiliation: Newmarket Equine Hospital, Suffolk, UK.
authors.forename: I M
authors.initials: IM
authors.lastname: Wright
mesh_terms: D000758:Anesthesia / Q000009:adverse effects / Q000662:veterinary*; D000818:Animals; D003085:Colic / Q000209:etiology / Q000662:veterinary*; D006734:Horse Diseases / Q000209:etiology*; D006736:Horses; D016017:Odds Ratio; D011183:Postoperative Complications / Q000662:veterinary*; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Thoroughbred; horse; peri-anaesthetic complications; post anaesthetic colic; sodium benzylpenicillin