title: Binding Studies of Cucurbit[7]uril with Gold Nanoparticles Bearing Different Surface Functionalities.
abstract: Host-guest interactions between a synthetic receptor, cucurbit[7]uril (CB[7]), and gold nanoparticles (AuNPs) have been quantified using isothermal titration calorimetry. AuNPs were functionalized with ligands containing tertiary or quaternary benzylamine derivatives, with electron donating or withdrawing groups at theparaposition of the benzene ring. Analysis of binding interactions reveals that functional groups at theparaposition have no significant effect on binding constant. However, headgroups bearing a permanent positive charge increased the binding of AuNPs to CB[7] ten-fold compared to monomethyl counterparts.
authors.affiliation: Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA.
authors.forename: Gulen Yesilbag
authors.initials: GY
authors.lastname: Tonga
authors.affiliation: Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA.
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Mizuhara
authors.affiliation: Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA.
authors.forename: Krishnendu
authors.initials: K
authors.lastname: Saha
authors.affiliation: Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA.
authors.forename: Ziwen
authors.initials: Z
authors.lastname: Jiang
authors.affiliation: Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA.
authors.forename: Singyuk
authors.initials: S
authors.lastname: Hou
authors.affiliation: Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA.
authors.forename: Riddha
authors.initials: R
authors.lastname: Das
authors.affiliation: Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA.
authors.forename: Vincent M
authors.initials: VM
authors.lastname: Rotello
keywords: Gold nanoparticle; cucurbit[7]uril; host-guest interaction; isothermal titration calorimetry; supramolecular chemistry