title: Ranolazine overdose-induced seizures.
abstract: Ranolazine is a new anti-anginal medication that was approved by the US Food and Drug Administration (FDA) in 2006 for patients with symptomatic chronic angina despite optimized therapy. This paper presents a case report of a fifteen year old male patient admitted to the pediatric intensive care unit after ranolazine overdose ingestion. He had recurrent new onset seizures that are most likely due to ranolazine overdose. Seizures have never been reported with ranolazine use or abuse.
authors.affiliation: Stead Family Department of Pediatrics, University of Iowa Children's Hospital, Iowa City, IA. Electronic address: nour-akil@uiowa.edu.
authors.forename: Nour
authors.initials: N
authors.lastname: Akil
authors.affiliation: Iowa Poison Control Center, Iowa City, IA.
authors.forename: Edward
authors.initials: E
authors.lastname: Bottei
authors.affiliation: Stead Family Department of Pediatrics, University of Iowa Children's Hospital, Iowa City, IA.
authors.forename: Sameer
authors.initials: S
authors.lastname: Kamath
mesh_terms: D000293:Adolescent; D002317:Cardiovascular Agents / Q000506:poisoning*; D062787:Drug Overdose; D015600:Glasgow Coma Scale; D006801:Humans; D008297:Male; D000069458:Ranolazine / Q000506:poisoning*; D012640:Seizures / Q000139:chemically induced*; D013406:Suicide, Attempted
chemical_list: D002317:Cardiovascular Agents; D000069458:Ranolazine