title: Prevalence and Clinical Characteristics of Psoriatic Arthritis in Japan.
abstract: OBJECTIVE
  To investigate the prevalence of psoriatic arthritis (PsA) in Japanese patients with psoriasis.
  
  
  METHODS
  A multicenter, noninterventional, retrospective cross-sectional study was conducted at 3 tertiary care centers in Japan. PsA was diagnosed by rheumatologists based on clinical findings. Prevalence of PsA, clinical characteristics, comorbidities, and treatment patterns were examined.
  
  
  RESULTS
  PsA was identified in 431 of 3021 patients with psoriasis, with a mean prevalence of 14.3% (range, 8.8-20.4%). No large differences between these results and previous reports from Western countries were observed in arthritis distribution, skin disease type, or treatment selection.
  
  
  CONCLUSIONS
  The prevalence of PsA in patients with psoriasis in Japan approaches 20% in some areas, similar to that observed in Western countries, and is higher than previously reported in Asia. Clinical features including age, sex, age at onset, and manifestation patterns were also similar to those reported in the West.
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Yuri
authors.initials: Y
authors.lastname: Ohara
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center. kishimotomi@gmail.com.
authors.forename: Mitsumasa
authors.initials: M
authors.lastname: Kishimoto
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Naoho
authors.initials: N
authors.lastname: Takizawa
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Yoshida
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Masato
authors.initials: M
authors.lastname: Okada
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Hikaru
authors.initials: H
authors.lastname: Eto
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Gautam A
authors.initials: GA
authors.lastname: Deshpande
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Christopher T
authors.initials: CT
authors.lastname: Ritchlin
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Tanaka
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Mari
authors.initials: M
authors.lastname: Higashiyama
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Matsui
authors.affiliation: From the Immuno-Rheumatology Center, and the Department of Dermatology, St. Luke's International Hospital, Tokyo; Department of Rheumatology, and the Department of Dermatology, Kameda Medical Center, Chiba, Japan; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center, Rochester, New York, USA; Department of Dermatology, Nissay Hospital; Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center, Osaka, Japan.Y. Ohara, MD*, M. Kishimoto, MD*, Immuno-Rheumatology Center, St. Luke's International Hospital; N. Takizawa, MD, Department of Rheumatology, Kameda Medical Center; K. Yoshida, MD, MPH, Department of Epidemiology, Harvard School of Public Health; M. Okada, MD, Immuno-Rheumatology Center, St. Luke's International Hospital; H. Eto, MD, Department of Dermatology, St. Luke's International Hospital; G.A. Deshpande, MD, MA, Immuno-Rheumatology Center, St. Luke's International Hospital; C.T. Ritchlin, MD, Allergy, Immunology, and Rheumatology Division, University of Rochester Medical Center; A. Tanaka, MD, Department of Dermatology, Kameda Medical Center; M. Higashiyama, MD, Department of Dermatology, Nissay Hospital; K. Matsui, MD, Department of Rheumatology, Kameda Medical Center; S. Tsuji, MD, Department of Orthopedics, National Hospital Organization, Osaka Minami Medical Center.
authors.forename: Shigeyoshi
authors.initials: S
authors.lastname: Tsuji
mesh_terms: D000328:Adult; D000368:Aged; D015535:Arthritis, Psoriatic / Q000175:diagnosis* / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies
keywords: ASIA; JAPAN; PREVALENCE; PSORIASIS; PSORIATIC ARTHRITIS