title: Hydrogel Nanofilaments via Core-Shell Electrospinning.
abstract: Recent biomedical hydrogels applications require the development of nanostructures with controlled diameter and adjustable mechanical properties. Here we present a technique for the production of flexible nanofilaments to be used as drug carriers or in microfluidics, with deformability and elasticity resembling those of long DNA chains. The fabrication method is based on the core-shell electrospinning technique with core solution polymerisation post electrospinning. Produced from the nanofibers highly deformable hydrogel nanofilaments are characterised by their Brownian motion and bending dynamics. The evaluated mechanical properties are compared with AFM nanoindentation tests.
authors.affiliation: Department of Mechanics and Physics of Fluids, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland.
authors.forename: Paweł
authors.initials: P
authors.lastname: Nakielski
authors.affiliation: Department of Mechanics and Physics of Fluids, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland.
authors.forename: Sylwia
authors.initials: S
authors.lastname: Pawłowska
authors.affiliation: Department of Mechanics and Physics of Fluids, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland.
authors.forename: Filippo
authors.initials: F
authors.lastname: Pierini
authors.affiliation: Faculty of Chemistry, University of Warsaw, Warsaw, Poland.
authors.forename: Wioletta
authors.initials: W
authors.lastname: Liwińska
authors.affiliation: Department of Mechanics and Physics of Fluids, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland.
authors.forename: Patryk
authors.initials: P
authors.lastname: Hejduk
authors.affiliation: Department of Mechanics and Physics of Fluids, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Zembrzycki
authors.affiliation: Faculty of Chemistry, University of Warsaw, Warsaw, Poland.
authors.forename: Ewelina
authors.initials: E
authors.lastname: Zabost
authors.affiliation: Department of Mechanics and Physics of Fluids, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, Poland.
authors.forename: Tomasz A
authors.initials: TA
authors.lastname: Kowalewski
mesh_terms: D020100:Hydrogels / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*
chemical_list: D020100:Hydrogels