title: A rare case of Primary Central Nervous System Lymphoma initially diagnosed as demyelinating encephalopathy.
abstract: We report a case of histopathologically-confirmed primary central nervous system lymphoma who was initially diagnosed as demyelinating encephalopathy. A 58-year-old woman was admitted with confusion and left hemiparesis. Head MR showed abnormal flaky hypointense T1 and hyperintense T2 signals at right thalamus, splenium of corpus callosum, bilateral cerebral peduncle, pons, medulla oblongata, basal ganglia and right corona radiata. Her mental status improved a little and she was discharged from hospital after neuroprotective treatment. 10 days after her discharge, her confusion appeared again with hallucination and unsteady walking. Pathological examination revealed non-Hodgkin's lymphoma (WHO classification: DLBCL). The patient continued to deteriorate after the surgery and died 10 days later.
authors.affiliation: Department of Neurology, the First Teaching Hospital of Jilin University, Changchun,, China.
authors.forename: Hongmei
authors.initials: H
authors.lastname: Meng
authors.affiliation: Department of Neurology, the First Teaching Hospital of Jilin University, Changchun,, China.
authors.forename: Chunkui
authors.initials: C
authors.lastname: Zhou
authors.affiliation: Department of Neurology, the First Teaching Hospital of Jilin University, Changchun,, China.
authors.forename: Qingbo
authors.initials: Q
authors.lastname: Hao
authors.affiliation: Department of Neurology, the First Teaching Hospital of Jilin University, Changchun,, China.
authors.forename: Jiguo
authors.initials: J
authors.lastname: Gao
authors.affiliation: Department of Neurology, the First Teaching Hospital of Jilin University, Changchun,, China.
authors.forename: Rensheng
authors.initials: R
authors.lastname: Zhang
authors.affiliation: Department of Neurology, the First Teaching Hospital of Jilin University, Changchun,, China.
authors.forename: Zan
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Neurology, the First Teaching Hospital of Jilin University, Changchun,, China.
authors.forename: Qun
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Department of Neurology, the First Teaching Hospital of Jilin University, Changchun,, China.
authors.forename: Shaokuan
authors.initials: S
authors.lastname: Fang
mesh_terms: D016543:Central Nervous System Neoplasms / Q000175:diagnosis* / Q000473:pathology; D003711:Demyelinating Diseases / Q000175:diagnosis; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged