title: Ethics of Cancer Gene Transfer Clinical Research.
abstract: Translation of cancer gene transfer confronts many familiar-and some distinctive-ethical challenges. In what follows, I survey three major ethical dimensions of cancer gene transfer development. Subheading 1 centers on the ethics of planning, designing, and reporting animal studies. Subheading 2 describes basic elements of human subjects protection as pertaining to cancer gene transfer. In Subheading 3, I describe how cancer gene transfer researchers have obligations to downstream consumers of the evidence they produce.
authors.affiliation: Studies in Translation, Ethics and Medicine (STREAM), Biomedical Ethics Unit/McGill University, 3647 Peel Street, Montreal, QC, Canada, H3A 1X1, jonathan.kimmelman@mcgill.ca.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Kimmelman
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000941:ethics*; D002986:Clinical Trials as Topic / Q000941:ethics; D018014:Gene Transfer Techniques / Q000941:ethics*; D006801:Humans; D009369:Neoplasms / Q000235:genetics*