title: Changes in absolute theta power in bipolar patients during a saccadic attention task.
abstract: The present study analyzed absolute theta power (ATP) in brain areas involved with attention in the three phase of BD while the patients performing a saccadic attention task. We hypothesized that patients in depression and mania states show a higher ATP compared to euthymic patients, since a higher ATP is indicative of attention deficit. We analyzed the frontal (F7, F3, Fz, F4 and F8) and central (C3, Cz and C4) areas. Thirty bipolar patients were enrolled in this study. The subjects performed a saccadic attention task while their brain activity pattern was recorded using quantitative electroencephalography (20 channels). Our results showed a main effect for group over C3, C4, Cz, F7, F4, F8 electrodes, and a main effect for moment over Cz, F7, F8 electrodes. These results indicate that both task and groups produce changes in theta activity in distinct cortical areas that participate in the organization of attention. Our results therefore demonstrate that, although it is well established in the literature that theta has a relevant role in the attention process, it is necessary to deepen the investigations to better understand the specifics of theta during visual processing tasks that have a demand for attention.
authors.affiliation: Neurophysiology and Neuropsychology of Attention, Institute of Psychiatry of the Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil.
authors.forename: Consuelo
authors.initials: C
authors.lastname: Cartier
authors.affiliation: Institute of Applied Neuroscience (IAN), Rio de Janeiro, Brazil.
authors.forename: Claudia
authors.initials: C
authors.lastname: Diniz
authors.affiliation: Neurophysiology and Neuropsychology of Attention, Institute of Psychiatry of the Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil.
authors.forename: Luiza
authors.initials: L
authors.lastname: Di Girogio
authors.affiliation: Institute of Applied Neuroscience (IAN), Rio de Janeiro, Brazil; Veiga de Almeida University (UVA), Rio de Janeiro, Brazil; Neurophysiology and Neuropsychology of Attention, Institute of Psychiatry of the Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil.
authors.forename: Juliana
authors.initials: J
authors.lastname: Bittencourt
authors.affiliation: Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of the Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil.
authors.forename: Mariana
authors.initials: M
authors.lastname: Gongora
authors.affiliation: Institute of Applied Neuroscience (IAN), Rio de Janeiro, Brazil; Neurophysiology and Neuropsychology of Attention, Institute of Psychiatry of the Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil.
authors.forename: Guaraci
authors.initials: G
authors.lastname: Ken Tanaka
authors.affiliation: Brain Mapping and Plasticity Laboratory, Federal University of Piauí (UFPI), Parnaíba, Brazil.
authors.forename: Silmar
authors.initials: S
authors.lastname: Teixeira
authors.affiliation: Division of Neurosurgery, University of São Paulo Medical School, Brazil; Laboratory of Psychophysiology, Department of Psychology and Phonoaudiology, UMESP, Brazil.
authors.forename: Luis F
authors.initials: LF
authors.lastname: Basile
authors.affiliation: Anxiety & Depression Laboratory, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil.
authors.forename: Fernanda
authors.initials: F
authors.lastname: Novis
authors.affiliation: Anxiety & Depression Laboratory, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil.
authors.forename: Luciana
authors.initials: L
authors.lastname: Angélica Silveira
authors.affiliation: Anxiety & Depression Laboratory, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil.
authors.forename: Rafael de Assis
authors.initials: Rde A
authors.lastname: da Silva
authors.affiliation: Biomedical Engineering Program, COPPE, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Mauricio
authors.initials: M
authors.lastname: Cagy
authors.affiliation: Anxiety & Depression Laboratory, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil; Department of Medical Specialities, State University of Rio de Janeiro (UERJ), Brazil.
authors.forename: Elie
authors.initials: E
authors.lastname: Cheniaux
authors.affiliation: Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of the Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil; Institute of Applied Neuroscience (IAN), Rio de Janeiro, Brazil; School of Physical Education, Bioscience Department (EEFD/UFRJ), Brazil.
authors.forename: Pedro
authors.initials: P
authors.lastname: Ribeiro
authors.affiliation: Institute of Applied Neuroscience (IAN), Rio de Janeiro, Brazil; Neurophysiology and Neuropsychology of Attention, Institute of Psychiatry of the Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil; School of Physical Education, Bioscience Department (EEFD/UFRJ), Brazil. Electronic address: bruna_velasques@yahoo.com.br.
authors.forename: Bruna
authors.initials: B
authors.lastname: Velasques
mesh_terms: D000328:Adult; D001288:Attention / Q000502:physiology*; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000503:physiopathology* / Q000523:psychology; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000503:physiopathology; D004569:Electroencephalography; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology; D006801:Humans; D008297:Male; D012438:Saccades / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted; D013223:Statistics as Topic; D013826:Theta Rhythm / Q000502:physiology*
keywords: Absolute theta power; Attention; Bipolar disorder; Quantitative electroencephalography; Saccadic eye movement; Sensorimotor integration