title: Intestinal type gastric adenocarcinoma with unusual synchronous metastases to the colorectum and bladder.
abstract: A 75-year-old male presented with difficult defecation and increasing urinary frequency over a few months. He had a significant history of previous partial gastrectomy for gastric carcinoma 20 years prior. Computed tomography of the abdomen and pelvis showed extensive lymphadenopathy, a gastric mass and rectal as well as bladder wall thickening with bilateral ureterohydronephrosis. Normal looking serosal surfaces of the bladder and bowel were seen on laparoscopy and a defunctioning ileostomy was created. Gastroscopy revealed a malignant mass while cystoscopy and sigmoidscopy found extensive tumour growth lining the mucosal surfaces. Biopsies from all sites were compatible with intestinal type adenocarcinoma of gastric origin with few signet ring cells. Metabolic response to palliative chemotherapy was good and the patient's symptoms have improved on follow-up four months post ileostomy. We discuss the immunohistochemical profile of the tumour and review the literature.
authors.affiliation: Isaac Seow-En, Department of General Surgery, Singapore General Hospital, Singapore 169608, Singapore.
authors.forename: Isaac
authors.initials: I
authors.lastname: Seow-En
authors.affiliation: Isaac Seow-En, Department of General Surgery, Singapore General Hospital, Singapore 169608, Singapore.
authors.forename: Francis
authors.initials: F
authors.lastname: Seow-Choen
keywords: Bladder; Colorectum; Gastric adenocarcinoma; Intestinal-type; Metastasis