title: Multiple co-circulating HIV-1 subtypes in the Middle East and North Africa.
abstract: HIV-1 incidence has been increasing more rapidly in the Middle East and North Africa than in any other global region. Despite this trend, HIV epidemiology in the region remains poorly defined. We conducted an analysis of 3284 publicly available HIV-1 sequences from 15 countries in the Middle East and North Africa to better characterize the regional epidemic. A phylogenetic tree based on the reverse transcriptase gene revealed a complex mosaic of diverse HIV subtypes and circulating recombinant forms across the region.
authors.affiliation: aUS Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring bThe Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA.
authors.forename: Morgane
authors.initials: M
authors.lastname: Rolland
authors.forename: Kayvon
authors.initials: K
authors.lastname: Modjarrad
mesh_terms: D000352:Africa, Northern / Q000453:epidemiology; D058872:Epidemics; D015658:HIV Infections / Q000453:epidemiology*; D015497:HIV-1 / Q000235:genetics*; D006801:Humans; D008877:Middle East / Q000453:epidemiology; D010802:Phylogeny