title: Impact of elevated cardiac biomarkers on mortality after vascular surgery procedures.
abstract: Concurrent cardiac disease is an important cause of morbidity and mortality in vascular surgical patients. Increasingly, cardiac biomarkers are used to identify cardiac injury in these high-risk patients. This review provides data demonstrating that perioperative troponin elevation correlates with poor short- and long-term outcomes for vascular surgical patients. In addition, the data demonstrate that patients with high circulating troponin levels fair worse than those with lower levels. Early identification of patients with cardiac injury using biomarkers allows timely diagnosis, risk stratification, and aggressive medical therapy for vascular surgical patients.
authors.affiliation: Department of Surgery, University of Tennessee School of Medicine-Knoxville, 1924 Alcoa Highway, Box U-11, Knoxville, TN 37920.
authors.forename: Ryan
authors.initials: R
authors.lastname: Buckley
authors.affiliation: Department of Surgery, University of Tennessee School of Medicine-Knoxville, 1924 Alcoa Highway, Box U-11, Knoxville, TN 37920. Electronic address: sstevens@utmck.edu.
authors.forename: Scott L
authors.initials: SL
authors.lastname: Stevens
mesh_terms: D015415:Biomarkers / Q000097:blood; D006331:Heart Diseases / Q000097:blood* / Q000175:diagnosis / Q000401:mortality; D006801:Humans; D011237:Predictive Value of Tests; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome; D014336:Troponin / Q000097:blood*; D015854:Up-Regulation; D014652:Vascular Diseases / Q000097:blood / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000401:mortality*
chemical_list: D015415:Biomarkers; D014336:Troponin