title: Experiential pleasure deficits in different stages of schizophrenia.
abstract: Prior research has found dampened anticipatory pleasure but relatively intact consummatory pleasure in people with first-episode and more chronic schizophrenia, but no study has examined anticipatory and consummatory pleasure across the schizophrenia spectrum. To confirm the factor structure of the Chinese version of the Temporal Experience Pleasure Scale (TEPS), which measures four components of anhedonia, we recruited 364 people with schizophrenia for confirmatory factor analysis. To examine anhedonia in people across the schizophrenia spectrum, we recruited people with first-episode (n=76) and chronic schizophrenia (n=45), people with schizotypal traits (n=210), first-degree relatives (n=45) of people with schizophrenia and healthy controls. Deficit in abstract anticipatory pleasure appeared to be most severe in people with chronic schizophrenia, while dampened abstract consummatory pleasure was observed in people with schizotypal personality features and in people with chronic schizophrenia. In addition, both abstract anticipatory and abstract consummatory pleasure were negatively correlated with negative schizotypal personality features and schizophrenia symptoms. Our results suggest that deficits in anticipatory pleasure are present across the schizophrenia spectrum, particularly in the abstract domain.
authors.affiliation: Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Li
authors.affiliation: Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China; Castle Peak Hospital, Hong Kong, China.
authors.forename: Simon S Y
authors.initials: SS
authors.lastname: Lui
authors.affiliation: Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China.
authors.forename: Fu-Lei
authors.initials: FL
authors.lastname: Geng
authors.affiliation: Haidian District Mental Health Prevent-Treatment Hospital, Beijing, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.affiliation: Haidian District Mental Health Prevent-Treatment Hospital, Beijing, China.
authors.forename: Wen-Xiu
authors.initials: WX
authors.lastname: Li
authors.affiliation: Beijing Anding Hospital, Capital Medical University, Beijing 100088, China.
authors.forename: Chuan-Yue
authors.initials: CY
authors.lastname: Wang
authors.affiliation: Psychiatry Research Center, Beijing Huilongguan Hospital, Beijing, China.
authors.forename: Shu-Ping
authors.initials: SP
authors.lastname: Tan
authors.affiliation: Castle Peak Hospital, Hong Kong, China.
authors.forename: Eric F C
authors.initials: EF
authors.lastname: Cheung
authors.affiliation: Department of Psychology, University of California, Berkeley, CA, United States.
authors.forename: Ann M
authors.initials: AM
authors.lastname: Kring
authors.affiliation: Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China. Electronic address: rckchan@psych.ac.cn.
authors.forename: Raymond C K
authors.initials: RC
authors.lastname: Chan
mesh_terms: D000208:Acute Disease; D000328:Adult; D059445:Anhedonia; D059031:Anticipation, Psychological; D002681:China; D002908:Chronic Disease; D018450:Disease Progression; D005190:Family / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D057181:Pleasure; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia; D012565:Schizophrenic Psychology; D012569:Schizotypal Personality Disorder / Q000523:psychology*
keywords: Anhedonia; Anticipatory pleasure; Consummatory pleasure; Schizophrenia spectrum disorders