title: Anion Recognition Triggered Nanoribbon-Like Self-Assembly: A Fluorescent Chemosensor for Nitrate in Acidic Aqueous Solution and Living Cells.
abstract: A water-soluble π-conjugated bispyridinium phenylenevinylene-based fluorogenic probe has been developed as a novel fluorescent chemosensor for highly selective, sensitive, and rapid detection of NO3(-) anion in acidic aqueous media. This system self-assembles to a nanoribbon as a result of ionic interaction. The positively charged chemosensor generates a nearly instantaneous significant fluorescence signal (475 vs 605 nm) in response to NO3(-) in the green/yellow spectral region, with a large Stokes shift (130 nm). The fluorescence changes can be attributed to the self-aggregation of the sensor triggered by ionic interaction, which occurs as a consequence of the subtle cooperation of electrostatic ionic bonding, van der Waals forces, and π-stacking of the π-conjugated aromatic moieties. Importantly, this chemosensor has been employed for the first time for the fluorescence detection of intracellular NO3(-) anion in cultured cells.
authors.affiliation: Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang, Guizhou 550025, China.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang, Guizhou 550025, China.
authors.forename: Shiyan
authors.initials: S
authors.lastname: Chen
authors.affiliation: Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang, Guizhou 550025, China.
authors.forename: Xin-Long
authors.initials: XL
authors.lastname: Ni
mesh_terms: D000143:Acids / Q000737:chemistry*; D000838:Anions / Q000032:analysis; D002470:Cell Survival; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure; D037742:Nanotubes, Carbon / Q000737:chemistry*; D009566:Nitrates / Q000032:analysis*; D010316:Particle Size; D012996:Solutions; D013050:Spectrometry, Fluorescence; D013499:Surface Properties; D014407:Tumor Cells, Cultured; D014867:Water / Q000737:chemistry
chemical_list: D000143:Acids; D000838:Anions; D005456:Fluorescent Dyes; D037742:Nanotubes, Carbon; D009566:Nitrates; D012996:Solutions; D014867:Water