title: Copper(II)-catalyzed oxidative N-nitrosation of secondary and tertiary amines with nitromethane under an oxygen atmosphere.
abstract: The combination of a catalytic amount of Cu(OTf)2 and less than a stoichiometric amount of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) under an O2 atmosphere effectively promoted the N-nitrosation of both secondary aromatic/aliphatic amines and tertiary aromatic amines with nitromethane (CH3NO2) leading to the preparation of N-nitrosamine derivatives.
authors.affiliation: Department of Pure and Applied Chemistry, Faculty of Science and Technology, Tokyo University of Science (RIKADAI), Noda, Chiba 278-8510, Japan. sakachem@rs.noda.tus.ac.jp.
authors.forename: Norio
authors.initials: N
authors.lastname: Sakai
authors.forename: Minoru
authors.initials: M
authors.lastname: Sasaki
authors.forename: Yohei
authors.initials: Y
authors.lastname: Ogiwara
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D009595:Nitroparaffins / Q000737:chemistry*; D015538:Nitrosation; D010100:Oxygen / Q000737:chemistry
chemical_list: D000588:Amines; D009595:Nitroparaffins; D003300:Copper; D008697:Methane; C008640:nitromethane; D010100:Oxygen