title: Dysgeusia in a Patient with Guillain-Barré Syndrome Associated with Acute Hepatitis E: A Case Report and Literature Review.
abstract: Guillain-Barré syndrome (GBS) is usually triggered by viral or bacterial infection. In addition, it was recently reported that infection with hepatitis E virus (HEV) also causes GBS. A 49-year-old man presented with acute-onset paralysis in all extremities and dysgeusia during an episode of acute hepatitis. Serological tests showed the presence of anti-HEV IgM antibodies and HEV-RNA in the serum. As an electrophysiological examination showed acute demyelinating polyradiculoneuropathy, the patient was diagnosed as HEV-associated GBS. Following the initiation of treatment with intravenous immunoglobulin, his paralysis and dysgeusia rapidly improved. This case suggests that HEV-associated GBS may rarely be complicated by dysgeusia.
authors.affiliation: Department of Neurology, Fukuoka University, Japan.
authors.forename: Masa-Aki
authors.initials: MA
authors.lastname: Higuchi
authors.forename: Jiro
authors.initials: J
authors.lastname: Fukae
authors.forename: Jun
authors.initials: J
authors.lastname: Tsugawa
authors.forename: Shinji
authors.initials: S
authors.lastname: Ouma
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Takahashi
authors.forename: Shunji
authors.initials: S
authors.lastname: Mishiro
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tsuboi
mesh_terms: D000208:Acute Disease; D004408:Dysgeusia / Q000821:virology*; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D016751:Hepatitis E / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D016752:Hepatitis E virus / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007155:Immunologic Factors / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D010243:Paralysis / Q000150:complications / Q000503:physiopathology* / Q000821:virology; D012367:RNA, Viral / Q000097:blood
chemical_list: D016756:Immunoglobulins, Intravenous; D007155:Immunologic Factors; D012367:RNA, Viral