title: Simultaneous Determination of 27 Pesticides in Ginseng by UPLC/MS/MS and Modified QuEChERS Procedure.
abstract: A novel, simple, and rapid method for the quantification of 27 commonly used pesticides in ginseng incorporating a modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) procedure was developed and validated. The pesticides were extracted with 1% acetic acid in acetonitrile and extracts purified by use of the mixed sorbents primary-secondary amine, C18, and graphitized carbon black. Quantitative analysis of all pesticides was performed by ultra-performance LC/MS/MS in the positive ionization mode in a single run due to the fast polarity switching capability of the mass spectrometer. Two precursor-product ion transitions were monitored for each compound in the multiple reaction monitoring mode. Quantification was carried out using matrix-matched standards for calibration. Recoveries of the proposed method from the spiked samples were achieved in the range 62.8-108.5%, and RSD ranged from 1.5 to 11.8%.
authors.affiliation: Tianjin University, School of Material Science and Engineering, Tianjin 300072, People's Republic of China.
authors.forename: Ruoxin
authors.initials: R
authors.lastname: Wu
authors.forename: Qiyong
authors.initials: Q
authors.lastname: Chen
authors.forename: Shujing
authors.initials: S
authors.lastname: Li
authors.forename: Guoliang
authors.initials: G
authors.lastname: Fan
mesh_terms: D002851:Chromatography, High Pressure Liquid; D007202:Indicators and Reagents; D057230:Limit of Detection; D005894:Panax / Q000737:chemistry*; D010573:Pesticide Residues / Q000032:analysis*; D010575:Pesticides / Q000032:analysis*; D010936:Plant Extracts / Q000032:analysis; D012015:Reference Standards; D015203:Reproducibility of Results; D053719:Tandem Mass Spectrometry
chemical_list: D007202:Indicators and Reagents; D010573:Pesticide Residues; D010575:Pesticides; D010936:Plant Extracts