title: The synthesis of heteroleptic phosphines.
abstract: Heteroleptic phosphines (R2PR(1)) are a class of essential ligands for inorganic and organometallic chemistry. However, the syntheses of these phosphines are often fraught with laborious synthetic hurdles. Consequently, a renewed interest in innovative synthetic methods to access heteroleptic phosphines is emerging. This Perspective presents an overview of modern synthetic approaches to heteroleptic phosphines as well as a discussion of the strengths and limitations of these synthetic methods. A major emphasis is placed on simple and direct routes to phosphines and significant synthetic innovations for P-C bond-forming reactions.
authors.affiliation: Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon, 97403 USA. dtyler@uoregon.edu.
authors.forename: Alexander J
authors.initials: AJ
authors.lastname: Kendall
authors.forename: David R
authors.initials: DR
authors.lastname: Tyler