title: [New therapeutical options for heavy gastrointestinal bleeding].
abstract: The number of patients taking new oral anticoagulants is rising, so is the number of serious bleeding events. In severe bleeding, the decision to start a procoagulant therapy is difficult to take. With Idarucizumab and Andexanet Alfa, specific antidotes have been developed against both, direct thrombin inhibitors as well as direct Factor Xa inhibitors. In the endoscopic treatment of severe gastrointestinal bleeding, alternative treatment options are available with Hemospray™, Endoclot™ and new hemostasis clips. Especially in the recurrent ulcer bleeding, the newly developed clips can achieve hemostasis and prevent an operational procedure.
authors.affiliation: III. Medizinische Klinik, Klinikum Augsburg.
authors.forename: Georg
authors.initials: G
authors.lastname: Braun
authors.affiliation: III. Medizinische Klinik, Klinikum Augsburg.
authors.forename: Helmut
authors.initials: H
authors.lastname: Messmann
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects*; D004621:Embolization, Therapeutic / Q000295:instrumentation* / Q000379:methods*; D019317:Evidence-Based Medicine; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced* / Q000517:prevention & control*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans
chemical_list: D000925:Anticoagulants; D006490:Hemostatics