title: Children: Are We Doing Enough?
abstract: Use of medicines in children is often off-label or off-evidence because essential information is lacking. Over the last two decades, consistent efforts have been made to render the regulatory framework more amenable to the needs of the pediatric population. Methodological progress is also evident. However, the consistent effort must be sustained.
authors.affiliation: Division of Clinical Pharmacology and Toxicology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Ito
mesh_terms: D000818:Animals; D006801:Humans; D007232:Infant, Newborn, Diseases / Q000188:drug therapy*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*
chemical_list: D004364:Pharmaceutical Preparations