title: Evaluation of the permeability of five desensitizing agents using computerized fluid filtration.
abstract: The aim of this study was to evaluate the permeability of five desensitizing agents using computerized fluid filtration (CFF) test method.
  
  
  
  Sixty dentin discs of 500 ± 200-mm-thick were prepared from middle dentin of bovine incisors without exposed the pulp and then randomly divided into five groups (n = 12). The permeability of the discs was measured using the CFF test method before and after application of the following desensitizers: Admira Protect (Voco, Cuxhaven, Germany), Seal and Protect (Dentsply, Konstanz, Germany), Sensi Kill (DFL, Brazil), Systemp Desensitizer (Ivoclar Vivadent, Liechtenstein), BisBlock (Bisco, USA). Fluid movement measurements were made at 2-min intervals for 8 min, and a mean of the values obtained was calculated for each specimen. The results were analyzed using Kruskal-Wallis test and Wilcoxon signed ranks tests with a significance threshold of P < 0.05.
  
  
  
  There were no significant differences in permeability among desensitizing agents (P > 0.05); however dentin permeability was reduced in all groups (P < 0.05).
  
  
  
  The in vitro fluid conductance of dentin discs were reduced by treating with these five desensitizing agents.
authors.affiliation: Department of Restorative Dentistry, Faculty of Dentistry, Abant Izzet Baysal University, Bolu, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Dundar
authors.forename: T
authors.initials: T
authors.lastname: Yavuz
authors.forename: H
authors.initials: H
authors.lastname: Orucoglu
authors.forename: L
authors.initials: L
authors.lastname: Daneshmehr
authors.forename: M
authors.initials: M
authors.lastname: Yalcin
authors.forename: A
authors.initials: A
authors.lastname: Sengun
mesh_terms: D000180:Acrylic Resins; D000818:Animals; D002417:Cattle; D003188:Composite Resins; D003804:Dentin / Q000187:drug effects*; D057133:Dentin Desensitizing Agents / Q000627:therapeutic use*; D003806:Dentin Permeability / Q000187:drug effects*; D003807:Dentin Sensitivity / Q000188:drug therapy* / Q000517:prevention & control; D019234:Dentinal Fluid / Q000502:physiology*; D004338:Drug Combinations; D005976:Glutaral; D008689:Methacrylates; D008963:Molar; D019815:Oxalic Acid; D011140:Polyurethanes; D012833:Siloxanes
chemical_list: D000180:Acrylic Resins; C514542:BisBlock; D003188:Composite Resins; D057133:Dentin Desensitizing Agents; D004338:Drug Combinations; D008689:Methacrylates; D011140:Polyurethanes; D012833:Siloxanes; C489334:Systemp.desensitizer; C513703:Vivadent; C479084:admira; D019815:Oxalic Acid; D005976:Glutaral