title: Optimal Scan Time of 18F-FDG PET in Identifying Therapeutic Efficacy Secondary to Radiofrequency Ablation of Lung Cancer: Case Report.
abstract: Positron emission tomography (PET)/computed tomography (CT)-guided radiofrequency ablation (RFA) has become a major treatment approach for small tumors. Identifying this quantitative dynamic 18F-2-fluoro-2-deoxy-d-glucose (18F-FDG) activity at the primary lesion can minimize misdiagnosis and allow an opportunity to reintervene. Here, we report 3 patients with nonsmall cell lung cancer (NSCLC) who underwent the ablative therapy with split-dose 18F-FDG fused PET/CT scans for early identification of residual tumors and follow-up evaluation of treatment. Our results indicate that reliable post-RFA imaging follow-up is critical in fast and efficient assessment of complete tumor resection in patients experienced the ablation procedure.
authors.affiliation: From the Department of Thoracic surgery (W-QZ, Y-LF, BH, SC, HL), Beijing Institute of Respiratory Diseases, Beijing Chaoyang Hospital; and Department of Nuclear Medicine (M-FY), Chaoyang Hospital, Capital Medical University, Beijing, China.
authors.forename: Wen-Qian
authors.initials: WQ
authors.lastname: Zhang
authors.forename: Yi-Li
authors.initials: YL
authors.lastname: Fu
authors.forename: Bin
authors.initials: B
authors.lastname: Hu
authors.forename: Shuo
authors.initials: S
authors.lastname: Chen
authors.forename: Min-Fu
authors.initials: MF
authors.lastname: Yang
authors.forename: Hui
authors.initials: H
authors.lastname: Li
mesh_terms: D001999:Bronchoscopy; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18