title: Duration of conventional cardiopulmonary resuscitation prior to extracorporeal cardiopulmonary resuscitation and survival among adult cardiac arrest patients.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the association between survival and the duration of conventional cardiopulmonary resuscitation (CCPR) prior to extracorporeal cardiopulmonary resuscitation (ECPR) and possible confounding factors.
  
  
  METHODS
  This was a retrospective analysis of 31 adults who received ECPR at an academic medical center between 2004 and 2013. Odds of 30-day survival and Kaplan Meier survival curves were compared among patients who received CCPR ⩾ 45 min (n=8, 26%) vs. <45 min (n=23, 74%).
  
  
  RESULTS
  There was a trend for greater survival up to 14 days in patients who received CCPR <45 vs. ⩾ 45 minutes (57% vs. 50%) with no significant difference at 30 days (OR 1.09, 95% CI 0.22-5.45) and survival did not differ by demographic factors.
  
  
  CONCLUSIONS
  More than half of all patients who received ECPR survived to 30 days. Longer duration CCPR was associated with reduced survival within 2 weeks, but not at 30 days.
authors.affiliation: SpecialtyCare Inc., University of Colorado Hospital, Aurora, CO, USA mosca.modo@gmail.com.
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Mosca
authors.affiliation: Department of Medicine, Columbia University Medical Center, New York, NY, USA.
authors.forename: David L
authors.initials: DL
authors.lastname: Narotsky
authors.affiliation: Department of Medicine, Columbia University Medical Center, New York, NY, USA.
authors.forename: Heidi
authors.initials: H
authors.lastname: Mochari-Greenberger
authors.affiliation: Department of Medicine, Columbia University Medical Center, New York, NY, USA.
authors.forename: Ming
authors.initials: M
authors.lastname: Liao
authors.affiliation: Department of Cardiovascular Perfusion, Columbia University Medical Center/New York Presbyterian Hospital, New York, NY, USA.
authors.forename: Linda
authors.initials: L
authors.lastname: Mongero
authors.affiliation: Department of Cardiovascular Perfusion, Columbia University Medical Center/New York Presbyterian Hospital, New York, NY, USA.
authors.forename: James
authors.initials: J
authors.lastname: Beck
authors.affiliation: Department of Cardiothoracic Surgery, Columbia University Medical Center, New York, NY, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Bacchetta
mesh_terms: D000328:Adult; D000368:Aged; D016887:Cardiopulmonary Resuscitation; D018572:Disease-Free Survival; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006323:Heart Arrest / Q000401:mortality* / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D013997:Time Factors
keywords: adults; conventional cardiopulmonary resuscitation; extracorporeal cardiopulmonary resuscitation; outcomes; survival