title: Posteroventrolateral pallidotomy through implanted DBS electrodes monitored by recording local field potentials.
abstract: This paper describes the use of globus pallidus internus (Gpi) local field potentials recorded through pre-implanted deep brain stimulation (DBS) electrodes on a patient affected by generalized dystonia. The recordings were made both before and after radiofrequency-induced posteroventrolateral bilateral stereotactic pallidotomy. LFP patterns and macroelectrode impedances were modified after the pallidotomy, along with the improvement of dystonic symptoms. After implantation, the DBS electrodes were used for subsequent bedside pallidotomies that were required by the evolution and/or persistence of symptoms. In our hands, LFPs were safe and effective in monitoring pallidotomy performed through DBS electrodes.
authors.affiliation: a Unit of Functional and Stereotactic Surgery, Fondazione IRCCS Istituto Neurologico "Carlo Besta" , Milan , Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Franzini
authors.affiliation: a Unit of Functional and Stereotactic Surgery, Fondazione IRCCS Istituto Neurologico "Carlo Besta" , Milan , Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Cordella
authors.affiliation: a Unit of Functional and Stereotactic Surgery, Fondazione IRCCS Istituto Neurologico "Carlo Besta" , Milan , Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Penner
authors.affiliation: c Clinical Center for Neurostimulation, Neurotechnologies and Movement Disorders, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico , Milan , Italy.
authors.forename: Manuela
authors.initials: M
authors.lastname: Rosa
authors.affiliation: a Unit of Functional and Stereotactic Surgery, Fondazione IRCCS Istituto Neurologico "Carlo Besta" , Milan , Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Messina
authors.affiliation: a Unit of Functional and Stereotactic Surgery, Fondazione IRCCS Istituto Neurologico "Carlo Besta" , Milan , Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Rizzi
authors.affiliation: b Department of Child Neurology , Fondazione IRCCS Istituto Neurologico "Carlo Besta" , Milan , Italy.
authors.forename: Nardo
authors.initials: N
authors.lastname: Nardocci
authors.affiliation: c Clinical Center for Neurostimulation, Neurotechnologies and Movement Disorders, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico , Milan , Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Priori
mesh_terms: D000293:Adolescent; D046690:Deep Brain Stimulation; D004421:Dystonia / Q000601:surgery; D004567:Electrodes, Implanted; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D064795:Intraoperative Neurophysiological Monitoring / Q000379:methods*; D019635:Neurosurgical Procedures / Q000379:methods*; D053860:Pallidotomy / Q000379:methods*; D013238:Stereotaxic Techniques; D016896:Treatment Outcome
keywords: dystonia; local field potentials; pallidotomy