title: Gingival crevicular blood as a source to screen for diabetes control in a dental office setting.
abstract: screen for diabetes control, this study compared glycosylated hemoglobin (HbAlc) levels found in GCB and serum. Methods: Patients diagnosed (n= 29), with diabetes received a venipuncture on the finger and serum blood (METHODS) obtained was tested for HbAlc status chair-side. GCB (test) was collected at site(s) with evidence of bleeding after probing and the HbAlc value was determined in the same manner as with the serum blood. Results: There was a significant correlation between serum blood and GCB using the HbAlc test. The Pearson
  
  
  RESULTS
  tion was 0.98 (P< 0.0001). The Altman-Bland bias was -0.21 (P= 0.0095), indicating that on average, the GCB method slightly underestimated the venipuncture serum (control) method for determining HbA1c values. The Altman-Bland 95% agreement interval ranged from -1.02 to 0.6. Furthermore, the HbAlc values were independent of the gingival sites used for collection with intra-patient GCB values exhibiting a correlation value between sites of 0.91 (P< 0.0001).
authors.forename: Jung-Wan
authors.initials: JW
authors.lastname: Kim
authors.forename: Ryan E
authors.initials: RE
authors.lastname: Wolff
authors.forename: Philippe
authors.initials: P
authors.lastname: Gaillard
authors.forename: Larry F
authors.initials: LF
authors.lastname: Wolff
mesh_terms: D000328:Adult; D003770:Dental Offices; D003920:Diabetes Mellitus / Q000097:blood / Q000517:prevention & control*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000517:prevention & control; D005883:Gingival Crevicular Fluid / Q000737:chemistry*; D005884:Gingival Hemorrhage / Q000097:blood*; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D008403:Mass Screening; D018962:Phlebotomy; D019095:Point-of-Care Systems; D011933:Reagent Kits, Diagnostic
chemical_list: D006442:Glycated Hemoglobin; D011933:Reagent Kits, Diagnostic