title: Comparison of clinical and radiographic results between isobar posterior dynamic stabilization and posterior lumbar inter-body fusion for lumbar degenerative disease: A four-year retrospective study.
abstract: OBJECTIVE
  A retrospective study was conducted to compare clinical outcome with radiographic data and clinical complications between isobar posterior dynamic stabilization (IPDS, Scient'x, France) and posterior lumbar inter-body fusion (PLIF) for lumbar degenerative disease.
  
  
  METHODS
  113 consecutive patients (IPDS group, N=62; PLIF group, N=51) with lumbar degenerative disease were operated on between March 2009 and November 2011. Patient charts, radiographic films and medical records were reviewed. Clinical outcomes including the visual analog scale (VAS), Oswestry disability index (ODI) scores, and radiographic outcomes, including disk height index (DHI) and range of motion (ROM) were retrospectively analyzed.
  
  
  RESULTS
  The ODI and VAS leg and back pain scores in two groups were significantly improved at 6 and, 24 months and at the final follow-up (all, P<0.05). The degree of improvements in the ODI and VAS back pain scores, the incidence of complications and the rate of adjacent segment degeneration were similar in both groups (P>0.05). However, operation times and blood loss were significantly reduced in the IPDS group (P<0.05).
  
  
  CONCLUSIONS
  In summary, with similar symptoms improvement and complication rates, the results of this study demonstrate that IPDS is an effective and safe treatment for lumbar degenerative disease. There is currently insufficient evidence to indicate that the IPDS can avoid adjacent segment degeneration therefore, it is essential to conduct prospective, randomized, controlled multicenter studies with larger sample size and longer follow-up.
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Operation Room, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Hong
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China. Electronic address: liuhao6304@163.com.
authors.forename: Hao
authors.initials: H
authors.lastname: Liu
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Yueming
authors.initials: Y
authors.lastname: Song
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Limin
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Quan
authors.initials: Q
authors.lastname: Gong
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D016268:Internal Fixators; D007405:Intervertebral Disc Displacement / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000601:surgery*; D008161:Lumbosacral Region / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013123:Spinal Fusion / Q000379:methods; D013130:Spinal Stenosis / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Fusion; IPDS; Isobar; Lumbar degenerative disease; PLIF; Posterior dynamic stabilization