title: Patient Mood and Instrumental Activities of Daily Living in Alzheimer Disease: Relationship Between Patient and Caregiver Reports.
abstract: This retrospective study investigated the relationship between self-reports and caregiver perceptions of patients' depressive symptoms and the respective ability of these reports to predict instrumental activities of daily living (IADLs) beyond what is accounted for by cognitive abilities in 71 patients with mild Alzheimer disease. Patients completed the Geriatric Depression Scale-Short Form, and caregivers completed the Behavior Rating Scale for Dementia assessing their perception of patients' depressive symptoms. Caregivers also completed IADL items from the Alzheimer's Disease Cooperative Study Activities of Daily Living Inventory. Cognitive measures included the Mini-Mental State Examination, Logical Memory from the Wechsler Memory Scale III, and Trail Making Test, Part B. The relationship between self-reported depressive symptoms and caregiver report of patients' depressive symptoms showed a trend toward significance (r = .22, P = .06). Measures of depressive symptoms significantly predicted 12.5% of the variance in IADLs performance, beyond that accounted for by patient demographics and cognitive functioning. Interestingly, patients' reports, rather than caregivers', were particularly useful in this prediction.
authors.affiliation: Department of Psychiatry, Neuropsychology Section, University of Michigan Medical Center, Ann Arbor, MI, USA kvotruba@umich.edu.
authors.forename: Kristen L
authors.initials: KL
authors.lastname: Votruba
authors.affiliation: Department of Psychiatry, Neuropsychology Section, University of Michigan Medical Center, Ann Arbor, MI, USA Michigan Alzheimer's Disease Center (MADC), Ann Arbor, MI, USA.
authors.forename: Carol
authors.initials: C
authors.lastname: Persad
authors.affiliation: Department of Psychiatry, Neuropsychology Section, University of Michigan Medical Center, Ann Arbor, MI, USA Michigan Alzheimer's Disease Center (MADC), Ann Arbor, MI, USA.
authors.forename: Bruno
authors.initials: B
authors.lastname: Giordani
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology*; D000339:Affect; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000150:complications / Q000175:diagnosis / Q000451:nursing / Q000523:psychology*; D017028:Caregivers / Q000523:psychology*; D003071:Cognition / Q000502:physiology; D003863:Depression / Q000150:complications / Q000523:psychology; D005260:Female; D015577:Geriatric Assessment / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology; D012189:Retrospective Studies; D057566:Self Report
keywords: Alzheimer disease; IADLs; caregiver report; geriatric depressive symptoms; self-report