title: Preeclampsia: What Does the Father Have to Do with It?
abstract: Preeclampsia (PE) is one of the leading causes of maternal and fetal morbidity and mortality, with incidence rates ranging between 2 and 5 % in the Western World. The exact causes of the disease remain largely unknown, because of the complex pathophysiologic mechanisms involved in the process. Genetic, environmental, and epigenetic parameters have been implicated by various authors as culprits for the pathogenesis of PE. Recent reports in the literature highlight the paternal role. Still, the exact extent and mechanism remain elusive. In this systematic review, we attempt to present data regarding the paternal role in a concise and comprehensive manner.
authors.affiliation: Cardiology Department, Hippokration Hospital, Athens, Greece.
authors.forename: V
authors.initials: V
authors.lastname: Katsi
authors.forename: I
authors.initials: I
authors.lastname: Felekos
authors.forename: C
authors.initials: C
authors.lastname: Siristatidis
authors.forename: S
authors.initials: S
authors.lastname: Kasioni
authors.forename: A
authors.initials: A
authors.lastname: Drakontaidis
authors.forename: G
authors.initials: G
authors.lastname: Farmakides
authors.forename: T
authors.initials: T
authors.lastname: Makris
authors.forename: C
authors.initials: C
authors.lastname: Aggeli
authors.forename: P
authors.initials: P
authors.lastname: Nihoyannopoulos
authors.forename: D
authors.initials: D
authors.lastname: Tousoulis
authors.forename: I
authors.initials: I
authors.lastname: Kallikazaros
mesh_terms: D005260:Female; D006801:Humans; D010290:Parents; D017410:Practice Guidelines as Topic; D011225:Pre-Eclampsia / Q000503:physiopathology; D011247:Pregnancy