title: Synthesis of magnetic molecularly imprinted polymers by reversible addition fragmentation chain transfer strategy and its application in the Sudan dyes residue analysis.
abstract: Magnetic molecularly imprinted polymers (MMIPs) have become a hotspot owing to the dual functions of target recognition and magnetic separation. In this study, the MMIPs were obtained by the surface-initiated reversible addition fragmentation chain transfer (RAFT) polymerization using Sudan I as the template. The resultant MMIPs were characterized by transmission electron microscope, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, vibrating sample magnetometer, and X-ray diffraction. Benefiting from the controlled/living property of the RAFT strategy, the uniform MIP layer was successfully grafted on the surface of RAFT agent-modified Fe3O4@SiO2 nanoparticles, favoring the fast mass transfer and rapid binding kinetics. The developed MMIPs were used as the solid-phase extraction sorbents to selectively extract four Sudan dyes (Sudan I, II, III, and IV) from chili powder samples. The recoveries of the spiked samples in chili powder samples ranged from 74.1 to 93.3% with RSD lower than 6.4% and the relative standard uncertainty lower than 0.029. This work provided a good platform for the extraction and removal of Sudan dyes in complicated matrixes and demonstrated a bright future for the application of the well-constructed MMIPs in the field of solid-phase extraction.
authors.affiliation: School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Xie
authors.affiliation: School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Chen
authors.affiliation: School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Pan
authors.affiliation: School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi'an 710061, China. Electronic address: wangsc@mail.xjtu.edu.cn.
authors.forename: Sicen
authors.initials: S
authors.lastname: Wang
mesh_terms: D001391:Azo Compounds / Q000032:analysis*; D004396:Coloring Agents / Q000032:analysis*; D005296:Ferrous Compounds; D008280:Magnetics; D054802:Molecular Imprinting; D053758:Nanoparticles; D009284:Naphthols / Q000032:analysis*; D056951:Photoelectron Spectroscopy; D058105:Polymerization; D011108:Polymers / Q000737:chemistry; D012822:Silicon Dioxide; D052616:Solid Phase Extraction / Q000379:methods; D017550:Spectroscopy, Fourier Transform Infrared; D017365:Spices / Q000032:analysis; D014961:X-Ray Diffraction
chemical_list: D001391:Azo Compounds; D004396:Coloring Agents; D005296:Ferrous Compounds; D009284:Naphthols; D011108:Polymers; C024336:1-phenylazo-2-naphthol; D012822:Silicon Dioxide; C034236:ferrous oxide
keywords: Chili powder samples; Magnetic molecularly imprinted polymers; Reversible addition fragmentation chain transfer polymerization; Sudan dyes