title: [Poor quality of sleep associated with low adherence to highly active antiretroviral therapy in Peruvian patients with HIV/AIDS].
abstract: This cross-sectional study analyzed the association between poor quality of sleep and adherence to highly active antiretroviral therapy (HAART) in 389 Peruvian patients with HIV/AIDS. Poor quality of sleep was measured with the Pittsburgh Sleep Quality Index (PSQI) and adherence with the CEAT-VIH (Peruvian adaptation). A Poisson generalized linear model with robust standard errors was used to estimate prevalence ratios and 95%CI. A crude model showed that mild, moderate, and severe poor quality of sleep were associated with inadequate treatment adherence. In the adjusted model for variables associated in the bivariate analysis or variables theoretically associated with adherence, only moderate/severe poor quality of sleep remained associated (PR = 1.34, 95%CI: 1.17-1.54; and PR = 1.34, 95%CI: 1.16-1.57, respectively). The study concluded that moderate/severe poor quality of sleep was independently associated with adherence to HAART. Assessing quality of sleep may be helpful in the comprehensive evaluation of HIV patients.
authors.affiliation: Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú
authors.forename: Jorge Renzo
authors.initials: JR
authors.lastname: Tello-Velásquez
authors.affiliation: Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú
authors.forename: Bruno Eduardo
authors.initials: BE
authors.lastname: Díaz-Llanes
authors.affiliation: Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú
authors.forename: Edward
authors.initials: E
authors.lastname: Mezones-Holguín
authors.affiliation: Facultad de Ciencias de la Salud, Universidad Tecnológica de Pereira, Pereira, Colombia.
authors.forename: Alfonso J
authors.initials: AJ
authors.lastname: Rodríguez-Morales
authors.affiliation: Centro Nacional de Salud Pública, Instituto Nacional de Salud, Lima, Perú
authors.forename: Charles
authors.initials: C
authors.lastname: Huamaní
authors.affiliation: Escuela de Medicina, Universidad Peruana de Ciencias Aplicadas, Lima, Perú
authors.forename: Adrián V
authors.initials: AV
authors.lastname: Hernández
authors.affiliation: Hospital Nacional Dos de Mayo, Lima, Perú
authors.forename: Jorge
authors.initials: J
authors.lastname: Arévalo-Abanto
mesh_terms: D000293:Adolescent; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D008875:Middle Aged; D010568:Peru; D016012:Poisson Distribution; D012720:Severity of Illness Index; D012893:Sleep Wake Disorders / Q000523:psychology*; D055815:Young Adult