title: Donor Contraindications to Living Kidney Donation: A Single-Center Experience.
abstract: OBJECTIVE
  Kidney transplantation is the treatment of choice in end-stage renal disease. In Turkey, the inadequate cadaveric donor supply has resulted in transplantation from living kidney donors (LKD) in 80% of transplant operations. LKD candidates undergo a thorough general medical evaluation and are approved to donate their kidneys only if no contraindication is found. In our study we aimed to investigate the reasons and rate of denial for living kidney donation in our center.
  
  
  METHODS
  We included all LKD candidates who applied to our center between June 2012 to June 2014. Demographic data, rate of rejection, and the reasons for denial to organ donation were analyzed retrospectively.
  
  
  RESULTS
  Of the 97 LKD candidates included in the study, 60 (62%) were unable to donate their kidneys. Among the reasons for denial were hypertension with target organ damage in 30% (n = 18), immunologic reasons in 23% (n = 14), impaired renal function in 20% (n = 12) cardiovascular reasons 13.3% (n = 8), diabetes mellitus in 10% (n = 6), malignity in 10% (n = 6), obesity (body mass index > 35 kg/m(2)) in 5% (n = 3), and miscellaneous in 18.3% (n = 11). There were >1 reasons in 13 candidates.
  
  
  CONCLUSIONS
  The problems detected in donor candidates offer a possibility for early detection of disorders and increased awareness.
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Bülent Ecevit University School of Medicine, Zonguldak, Turkey.
authors.forename: K
authors.initials: K
authors.lastname: Mağden
authors.affiliation: Marmara University School of Medicine, Turkey.
authors.forename: F B
authors.initials: FB
authors.lastname: Ucar
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Marmara University School of Medicine Hospital, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Velioğlu
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Marmara University School of Medicine Hospital, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Arıkan
authors.affiliation: Department of General Surgery, Marmara University School of Medicine Hospital, Turkey.
authors.forename: Ş C
authors.initials: ŞC
authors.lastname: Yeğen
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Marmara University School of Medicine Hospital, Turkey. Electronic address: serhantuglular@yahoo.com.
authors.forename: S
authors.initials: S
authors.lastname: Tuğlular
authors.affiliation: Division of Nephrology, Department of Internal Medicine, Marmara University School of Medicine Hospital, Turkey.
authors.forename: I Ç
authors.initials: IÇ
authors.lastname: Özener
mesh_terms: D000328:Adult; D015992:Body Mass Index; D000075202:Contraindications; D046148:Donor Selection / Q000379:methods*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D012189:Retrospective Studies; D020858:Tissue and Organ Harvesting; D014421:Turkey