title: Spinal dysraphisms in the parturient: implications for perioperative anaesthetic care and labour analgesia.
abstract: Anaesthetists may encounter parturients with a spectrum of anatomical and functional abnormalities secondary to spinal dysraphisms, which are among the most common neurodevelopmental anomalies. These range from surgically corrected open dysraphisms to previously undiagnosed closed dysraphisms. Both bony and neural structures may be abnormal. In true bony spina bifida, which occurs in up to 50% of the population, failure of fusion of the vertebral arch is seen and neural structures are normal. Ninety percent of such cases are confined to the sacrum. In open dysraphisms, sensory preservation is variable and may be present even in those with grossly impaired motor function. Both epidural and spinal blockade have been described for labour analgesia and operative anaesthesia in selected cases but higher failure and complication rates are reported. Clinical assessment should be performed on an outpatient basis to assess neurological function, evaluate central nervous system shunts and determine latex allergy status. Magnetic resonance imagining is recommended to clarify anatomical abnormalities and to identify levels at which neuraxial techniques can be performed. Of particular concern when performing neuraxial blockade is the possibility of a low-lying spinal cord or conus medullaris and spinal cord tethering. Previous corrective de-tethering surgery frequently does not result in ascent of the conus and re-tethering may be asymptomatic. Ultrasound is not sufficiently validated at the point of care to reliably detect low-lying cords. Epidurals should be performed at anatomically normal levels but spread of local anaesthetic may be impaired by previous surgery.
authors.affiliation: The Rotunda Hospital, Parnell Square, Dublin, Ireland.
authors.forename: C J
authors.initials: CJ
authors.lastname: Murphy
authors.affiliation: Mater Misericordiae University Hospital, Dublin, Ireland.
authors.forename: E
authors.initials: E
authors.lastname: Stanley
authors.affiliation: Mater Misericordiae University Hospital, Dublin, Ireland; School of Medicine and Medical Sciences, University College Dublin, Belfield, Dublin, Ireland.
authors.forename: E
authors.initials: E
authors.lastname: Kavanagh
authors.affiliation: Mater Misericordiae University Hospital, Dublin, Ireland; Children's University Hospital, Temple Street, Dublin, Ireland.
authors.forename: P E
authors.initials: PE
authors.lastname: Lenane
authors.affiliation: The Rotunda Hospital, Parnell Square, Dublin, Ireland; Mater Misericordiae University Hospital, Dublin, Ireland; School of Medicine and Medical Sciences, University College Dublin, Belfield, Dublin, Ireland. Electronic address: cmccaul@rotunda.ie.
authors.forename: C L
authors.initials: CL
authors.lastname: McCaul
mesh_terms: D016362:Analgesia, Obstetrical / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000379:methods*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D019990:Perioperative Care; D011247:Pregnancy; D016135:Spinal Dysraphism / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology; D013131:Spine / Q000000981:diagnostic imaging; D014463:Ultrasonography