title: Voice Outcomes of Transoral Laser Microsurgery of the Larynx.
abstract: Transoral laser microsurgery (TLM) is the mainstay in the treatment of early (TisT1T2) glottic cancer. Current knowledge concerning voice quality and voice-related quality of life in patients treated using TLM is based on small cohort studies using various instruments to evaluate these functional results. The bulk of the literature indicates that subjective and objective measurements of voice quality can return to normal or almost normal values after TLM, generally after 6 to 12 months and particularly after cordectomy types I, II, and III.
authors.affiliation: Service Rhône, Department of Head and Neck Oncology, Institut de Cancérologie Gustave Roussy, 114 rue Edouard Vaillant, Villejuif 94805, France. Electronic address: dana.hartl@gustaveroussy.fr.
authors.forename: Dana M
authors.initials: DM
authors.lastname: Hartl
authors.affiliation: Department of Head and Neck Oncology, Institut de Cancérologie Gustave Roussy, 114 rue Edouard Vaillant, Villejuif 94805, France.
authors.forename: Samia
authors.initials: S
authors.lastname: Laoufi
authors.affiliation: Otolaryngology-Head and Neck Surgery, University Hospital Cancer Specialities Pole, University Paris Descartes and Sorbonne Nouvelle, Hôpital Européen Georges Pompidou, 20, rue Leblanc, Paris 75908 Cedex 15, France.
authors.forename: Daniel F
authors.initials: DF
authors.lastname: Brasnu
mesh_terms: D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery*; D007830:Larynx / Q000601:surgery*; D053685:Laser Therapy / Q000379:methods*; D015201:Meta-Analysis as Topic; D008866:Microsurgery / Q000379:methods*; D011788:Quality of Life; D016896:Treatment Outcome; D014833:Voice Quality / Q000528:radiation effects*
keywords: Cancer; Glottis; Larynx; Laser; Surgery; Voice