title: Outbreak Control and Clinical, Pathological, and Epidemiological Aspects and Molecular Characterization of a Bovine Herpesvirus Type 5 on a Feedlot Farm in São Paulo State.
abstract: This paper describes the control, epidemiological, pathological, and molecular aspects of an outbreak of meningoencephalitis in calves due to bovine herpesvirus 5 at a feedlot with 540 animals in São Paulo State, Brazil. The introduction of new animals and contact between the resident animals and the introduced ones were most likely responsible for virus transmission. Bovine herpesvirus 1 vaccine was used, resulting in the efficacy of the outbreak control, although two bovine herpesvirus 1 positive animals, vaccinated and revaccinated, presented meningoencephalitis, thereby characterizing vaccinal failure.
authors.affiliation: Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinaria e Zootecnia, Departamento de Higiene Veterinária e Saude Publica, 18618-970 Botucatu, SP, Brazil.
authors.forename: Jane
authors.identifier: 0000-0002-6540-7157
authors.initials: J
authors.lastname: Megid
authors.affiliation: Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinaria e Zootecnia, Departamento de Higiene Veterinária e Saude Publica, 18618-970 Botucatu, SP, Brazil.
authors.forename: Acácia
authors.initials: A
authors.lastname: Ferreira Vicente
authors.affiliation: Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinaria e Zootecnia, Departamento de Higiene Veterinária e Saude Publica, 18618-970 Botucatu, SP, Brazil.
authors.forename: Camila Michele
authors.initials: CM
authors.lastname: Appolinario
authors.affiliation: Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinaria e Zootecnia, Departamento de Higiene Veterinária e Saude Publica, 18618-970 Botucatu, SP, Brazil.
authors.forename: Susan Dora
authors.initials: SD
authors.lastname: Allendorf
authors.affiliation: Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinaria e Zootecnia, Departamento de Higiene Veterinária e Saude Publica, 18618-970 Botucatu, SP, Brazil.
authors.forename: Mateus
authors.identifier: 0000-0001-7886-1570
authors.initials: M
authors.lastname: de Souza Ribeiro Mioni
authors.affiliation: Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinaria e Zootecnia, Departamento de Higiene Veterinária e Saude Publica, 18618-970 Botucatu, SP, Brazil.
authors.forename: Thaís
authors.initials: T
authors.lastname: Gasparini Baraldi
authors.affiliation: Universidade de Santo Amaro (UNISA), Faculdade de Medicina Veterinária, 04829-300 São Paulo, SP, Brazil.
authors.forename: Adriana
authors.initials: A
authors.lastname: Cortez
authors.affiliation: Universidade de São Paulo (USP), Faculdade de Medicina Veterinária e Zootecnia, Departamento de Medicina Veterinária Preventiva e Saúde Animal, 05508-270 São Paulo, SP, Brazil.
authors.forename: Marcos
authors.initials: M
authors.lastname: Bryan Heinemann
authors.affiliation: Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinaria e Zootecnia, Departamento de Higiene Veterinária e Saude Publica, 18618-970 Botucatu, SP, Brazil.
authors.forename: Clovis
authors.initials: C
authors.lastname: Reinaldo Silva Fonseca
authors.affiliation: Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinaria e Zootecnia, Departamento de Higiene Veterinária e Saude Publica, 18618-970 Botucatu, SP, Brazil.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Cristina Pelícia
authors.affiliation: Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina Veterinaria e Zootecnia, Departamento de Higiene Veterinária e Saude Publica, 18618-970 Botucatu, SP, Brazil.
authors.forename: Bruna Leticia
authors.initials: BL
authors.lastname: Devidé Ribeiro
authors.affiliation: Instituto Biológico de São Paulo, Laboratório de Viroses dos Bovídeos, São Paulo, SP, Brazil.
authors.forename: Liria
authors.initials: L
authors.lastname: Hiromi Okuda
authors.affiliation: Instituto Biológico de São Paulo, Laboratório de Viroses dos Bovídeos, São Paulo, SP, Brazil.
authors.forename: Edviges Maristela
authors.initials: EM
authors.lastname: Pituco
mesh_terms: D000383:Agriculture; D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology; D001938:Brazil; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D004196:Disease Outbreaks; D006566:Herpesviridae Infections / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D007242:Herpesvirus 1, Bovine / Q000276:immunology / Q000472:pathogenicity; D025881:Herpesvirus 5, Bovine / Q000276:immunology* / Q000472:pathogenicity; D014765:Viral Vaccines / Q000008:administration & dosage* / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines