title: Massive haemoptysis from a central pulmonary arterial pseudoaneurysm secondary to advanced lung cancer: successful treatment by Guglielmi detachable coil embolization.
abstract: Massive haemoptysis is a life-threatening condition in patients with lung cancer. Endovascular embolization has been well-established as an effective means of treating this condition. Haemoptysis of pulmonary arterial origin is rare, and a pulmonary artery pseudoaneurysm (PAP) is generally the main cause. PAP due to lung cancer is also very rare, and the site of bleeding always involves the peripheral lung. We report an unusual case of central PAP secondary to advanced central squamous-cell carcinoma of the lung in a patient with acute massive haemoptysis. The sac of the pseudoaneurysm underwent successful embolization using various Guglielmi detachable coils (GDCs). The patient died of lung cancer without recurrence of haemoptysis 42 days post-embolization. To the best of our knowledge, this case report is the first to describe massive haemoptysis caused by central PAP due to lung cancer and its successful treatment by GDC embolization.
authors.affiliation: Department of Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Radiology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, China.
authors.forename: Sen
authors.initials: S
authors.lastname: Jiang
mesh_terms: D000368:Aged; D017541:Aneurysm, False / Q000209:etiology / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D004621:Embolization, Therapeutic / Q000379:methods; D017809:Fatal Outcome; D006469:Hemoptysis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D011651:Pulmonary Artery / Q000473:pathology*
keywords: endovascular embolization - haemoptysis - lung cancer - pulmonary artery pseudoaneurysm