title: [Application of principles of "fast track" surgery in treatment of calculous cholecystitis].
abstract: The "fast track" concept in surgery provides rapid rehabilitation of postoperative patients, using the operative trauma reduction, adequate anesthesia--for reduction of the organism stress answer on surgical intervention. Results of treatment were analyzed in 118 patients, in whom for calculous cholecystitis the one-port transumbilical laparoscopic cholecystectomy (OPTLCH) was performed. Duration of the patients stationary treatment without abdominal cavity drainage have constituted at average (1.49 ± 0.05) days, after drainage--2.22 days. Intensity of the pain impulsation, which was determined in accordance to concentration of proinflammatory cytokins, including interleukin-1 (IL-1) and a tumor necrosis factor-α (TNF-α) after standard laparoscopic cholecystectomy (LCH) was in 1.2 times higher, than after OPTLCH. In subjective estimation of the pain intensity in accordance to visual analogous scale in patients after OPTLCH have constituted (3.42 ± 0.16) cm, and after a standard one--(5.98 ± 0.19) cm (p < 0.05).
authors.forename: Yu
authors.initials: Y
authors.lastname: Joffe
authors.forename: P
authors.initials: P
authors.lastname: Stetsenko
authors.forename: O A
authors.initials: OA
authors.lastname: Tykhonov
authors.forename: T V
authors.initials: TV
authors.lastname: Tarasyuk
authors.forename: Yu P
authors.initials: YP
authors.lastname: Tsyura
authors.forename: M S
authors.initials: MS
authors.lastname: Kryvopustov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D017081:Cholecystectomy, Laparoscopic / Q000379:methods*; D041881:Cholecystitis, Acute / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005704:Gallbladder / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D042882:Gallstones / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007375:Interleukin-1 / Q000097:blood; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000503:physiopathology / Q000523:psychology; D010147:Pain Measurement; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000097:blood
chemical_list: D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha