title: Oxidative Stress and Adult Neurogenesis.
abstract: There is a growing evidence that adult neurogenesis is critical for brain function. The reactive oxygen species (ROS) is accumulated during adult neurogenesis as a physiological mechanism; while ROS overload impairs adult neurogenesis during ageing, neuroinflammation and neurodegeneration. Here we propose that targeting oxidative stress provides a novel way to regulate adult neurogenesis and manage different brain diseases.
authors.affiliation: School of Psychology, Nanjing Normal University, Nanjing, China, ytf0707@126.com.
authors.forename: Ti-Fei
authors.initials: TF
authors.lastname: Yuan
authors.forename: Simeng
authors.initials: S
authors.lastname: Gu
authors.forename: Chunlei
authors.initials: C
authors.lastname: Shan
authors.forename: Sergio
authors.initials: S
authors.lastname: Marchado
authors.forename: Oscar
authors.initials: O
authors.lastname: Arias-Carrión
mesh_terms: D000328:Adult; D000818:Animals; D001921:Brain / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D055495:Neurogenesis / Q000502:physiology*; D009474:Neurons / Q000378:metabolism / Q000502:physiology*; D018384:Oxidative Stress / Q000502:physiology*; D017382:Reactive Oxygen Species / Q000378:metabolism
chemical_list: D017382:Reactive Oxygen Species