title: RETRACTED: Laryngeal Function After Radiation Therapy.
abstract: Laryngeal function after oncologic treatment is a key aspect and focus of interest in the contemporary management of head and neck cancers. Although historically the treatment of most locally advanced laryngeal cancers has been total laryngectomy, recent innovations in radiation therapy and combined chemotherapy and radiation therapy have shown that organ and function preservation can be achieved with good oncologic outcomes. Technical improvements, along with better understanding of tumor biology and dose tolerance of critical organs involved in speech and swallowing function, have paved the way for better outcomes. This article reviews in comprehensive detail the recent data of laryngeal function after radiotherapy.
authors.affiliation: Department of Radiation Oncology, Mayo Clinic Hospital, Mayo Clinic Arizona, Mayo Clinic Specialty Building, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA.
authors.forename: Mauricio
authors.initials: M
authors.lastname: Gamez
authors.affiliation: Department of Radiation Oncology, NYU-Langone Medical Center, 550 First avenue, New York, NY 10016, USA.
authors.forename: Kenneth
authors.initials: K
authors.lastname: Hu
authors.affiliation: Department of Radiation Oncology, Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA. Electronic address: Louis.harrison@moffitt.org.
authors.forename: Louis B
authors.initials: LB
authors.lastname: Harrison
mesh_terms: D059248:Chemoradiotherapy / Q000009:adverse effects*; D003679:Deglutition / Q000528:radiation effects*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000628:therapy*; D007825:Laryngectomy / Q000379:methods; D007830:Larynx / Q000503:physiopathology*; D059351:Organ Sparing Treatments / Q000379:methods; D011788:Quality of Life; D014833:Voice Quality / Q000528:radiation effects*
keywords: Dysphagia; Function; Speech; Voice