title: Vascular Dysfunction: A Key Player in Chronic Cardio-renal Syndrome.
abstract: This review summarizes the current methods for the functional assessment of vascular damage (e.g., assessment of endothelial function, measurement of pulse wave velocity, and pressure wave analysis) and describes the association between vascular dysfunction and chronic cardio-renal syndrome. Vascular dysfunction may contribute to the development and progression of heart failure. Additionally, vascular dysfunction, especially increased arterial stiffness and abnormal pressure wave reflection and central hemodynamics, has been reported to accelerate renal function decline. Furthermore, renal dysfunction worsens vascular pathophysiological abnormalities. Therefore, the functional assessment of vascular damage may be useful in the management of cardio-renal syndrome.
authors.affiliation: Department of Cardiology, Tokyo Medical University, Japan.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Tomiyama
authors.forename: Akira
authors.initials: A
authors.lastname: Yamashina
mesh_terms: D062186:Arterial Pressure; D001794:Blood Pressure; D059347:Cardio-Renal Syndrome / Q000473:pathology / Q000503:physiopathology*; D002339:Carotid Arteries / Q000503:physiopathology*; D002908:Chronic Disease; D005260:Female; D006352:Heart Ventricles / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D063177:Pulse Wave Analysis; D059289:Vascular Stiffness