title: Nucleophilic Functionalization of the Calix[6]arene Para- and Meta-Position via p-Bromodienone Route.
abstract: It is here demonstrated that the p-bromodienone route, previously reported for calix[4]arenes, is also effective for the functionalization of the calix[6]arene macrocycle. Thus, alcoholic O-nucleophiles can be introduced at the calix[6]arene exo rim. In addition, the reaction of a calix[6]arene p-bromodienone derivative with an actived aromatic substrate, such as resorcinol, led to the first example of a meta-functionalized, inherently chiral calix[6]arene derivative.
authors.affiliation: Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni Paolo II 132, I-84084 Fisciano, Salerno, Italy.
authors.forename: Margherita
authors.initials: M
authors.lastname: De Rosa
authors.affiliation: Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni Paolo II 132, I-84084 Fisciano, Salerno, Italy.
authors.forename: Annunziata
authors.initials: A
authors.lastname: Soriente
authors.affiliation: Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni Paolo II 132, I-84084 Fisciano, Salerno, Italy.
authors.forename: Gerardo
authors.initials: G
authors.lastname: Concilio
authors.affiliation: Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni Paolo II 132, I-84084 Fisciano, Salerno, Italy.
authors.forename: Carmen
authors.initials: C
authors.lastname: Talotta
authors.affiliation: Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni Paolo II 132, I-84084 Fisciano, Salerno, Italy.
authors.forename: Carmine
authors.initials: C
authors.lastname: Gaeta
authors.affiliation: Dipartimento di Chimica e Biologia, Università di Salerno, Via Giovanni Paolo II 132, I-84084 Fisciano, Salerno, Italy.
authors.forename: Placido
authors.initials: P
authors.lastname: Neri