title: Secretory breast carcinoma in a 41-year-old man with long-term follow-up: a special report.
abstract: Secretory breast carcinoma (SBC) is a rare tumor that is particularly rare in male adults. To our knowledge, only 28 previous male cases of secretory breast carcinoma have been reported. The present a case of secretory breast carcinoma has the longest symptom duration of (40 years) in a male individual until now. Typically, the clinical features and treatment of male SBC are similar with female SBC. The ETV6-NTRK3 fusion gene is a specific genetic alteration in SBC. When compared to other types of male breast cancer, patients with male secretory breast cancer are much younger, and have a lower rate of estrogen/progesterone hormone receptor positivity. Modified radical mastectomy has been favored as a therapeutic approach in all female SBC, male SBC and other types of male breast cancer. [corrected].
authors.affiliation: Department of Breast Surgery, Hainan Province People's Hospital, Haikou, Hainan, PR China.
authors.forename: Guanqiao
authors.initials: G
authors.lastname: Li
authors.affiliation: Department of Breast Surgery, Hainan Province People's Hospital, Haikou, Hainan, PR China.
authors.forename: Xiaojie
authors.initials: X
authors.lastname: Zhong
authors.affiliation: Department of Breast Surgery, Hainan Province People's Hospital, Haikou, Hainan, PR China.
authors.forename: Jia
authors.initials: J
authors.lastname: Yao
authors.affiliation: Department of Pathology, Hainan Province People's Hospital, Haikou, Hainan, PR China.
authors.forename: Jimin
authors.initials: J
authors.lastname: Chen
authors.affiliation: Department of Breast Surgery, Hainan Province People's Hospital, Haikou, Hainan, PR China.
authors.forename: Mei
authors.initials: M
authors.lastname: Wang
authors.affiliation: Department of Breast Surgery, Hainan Province People's Hospital, Haikou, Hainan, PR China.
authors.forename: Haiying
authors.initials: H
authors.lastname: Liu
authors.affiliation: Department of Radiation Oncology, Hainan Province People's Hospital, Haikou, Hainan, PR China.
authors.forename: Shiping
authors.initials: S
authors.lastname: Yang
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D018567:Breast Neoplasms, Male / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D014463:Ultrasonography
keywords: breast; clinical feature; male; secretory carcinoma; treatment