title: Diagnostic utility of endoscopic ultrasound-guided fine-needle aspiration biopsy for glomus tumor of the stomach.
abstract: A 52-year-old man was referred for further investigation of a gastric submucosal tumor on the greater curvature of the antrum. Endoscopic ultrasonography demonstrated a hypoechoic solid mass, which was primarily connected to the muscular layer of the stomach. We performed endoscopic ultrasound-guided fine-needle aspiration biopsy. The pathological examination showed proliferation of oval-shaped cells with nest formation, which stained strongly positive for muscle actin, and negative for c-kit, CD34, CD56, desmin, S-100, chromogranin, and neuron-specific enolase. Therefore, we performed laparoscopy and endoscopy cooperative surgery based on the preoperative diagnosis of glomus tumor of the stomach. The final histological diagnosis confirmed the preoperative diagnosis. Although preoperative diagnosis of glomus tumor of the stomach is difficult with conventional images and endoscopic biopsy, endoscopic ultrasound-guided fine-needle aspiration biopsy is an essential tool to gain histological evidence of glomus tumor of the stomach for early diagnosis.
authors.affiliation: Shin Kato, Kaoru Kikuchi, Kenji Chinen, Department of Gastroenterology, Okinawa Prefectural Chubu Hospital, Okinawa 904-2293, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Kato
authors.affiliation: Shin Kato, Kaoru Kikuchi, Kenji Chinen, Department of Gastroenterology, Okinawa Prefectural Chubu Hospital, Okinawa 904-2293, Japan.
authors.forename: Kaoru
authors.initials: K
authors.lastname: Kikuchi
authors.affiliation: Shin Kato, Kaoru Kikuchi, Kenji Chinen, Department of Gastroenterology, Okinawa Prefectural Chubu Hospital, Okinawa 904-2293, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Chinen
authors.affiliation: Shin Kato, Kaoru Kikuchi, Kenji Chinen, Department of Gastroenterology, Okinawa Prefectural Chubu Hospital, Okinawa 904-2293, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Murakami
authors.affiliation: Shin Kato, Kaoru Kikuchi, Kenji Chinen, Department of Gastroenterology, Okinawa Prefectural Chubu Hospital, Okinawa 904-2293, Japan.
authors.forename: Fumihito
authors.initials: F
authors.lastname: Kunishima
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D049109:Cell Proliferation; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D005743:Gastrectomy / Q000379:methods; D005773:Gastroscopy; D005918:Glomus Tumor / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011706:Pyloric Antrum / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D013274:Stomach Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor
keywords: Endoscopic ultrasound-guided fine-needle aspiration biopsy; Glomus tumor; Preoperative diagnosis; Stomach