title: Ophthalmic use of blood-derived products.
abstract: There is a wide spectrum of blood-derived products that have been used in many different medical and surgical specialties with success. Blood-derived products for clinical use can be extracted from autologous or allogeneic specimens of blood, but recombinant products are also commonly used. A number of blood derivatives have been used for a wide range of ocular conditions, from the ocular surface to the retina. With stringent preparation guidelines, the potential risk of transmission of blood-borne diseases is minimized. We review blood-derived products and how they are improving the management of ocular disease.
authors.affiliation: City Eye Centre, Brisbane, Queensland, Australia.
authors.forename: Ryan B
authors.initials: RB
authors.lastname: Nugent
authors.affiliation: City Eye Centre, Brisbane, Queensland, Australia; Department of Ophthalmology, University of Queensland, Brisbane, Queensland, Australia. Electronic address: eye@cityeye.com.au.
authors.forename: Graham A
authors.initials: GA
authors.lastname: Lee
mesh_terms: D000418:Albumins / Q000627:therapeutic use; D001769:Blood; D001798:Blood Proteins / Q000627:therapeutic use*; D003941:Diagnostic Techniques, Ophthalmological; D005169:Factor VIII / Q000627:therapeutic use; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use; D005340:Fibrinogen / Q000627:therapeutic use; D005353:Fibronectins / Q000627:therapeutic use; D006801:Humans; D013508:Ophthalmologic Surgical Procedures; D053657:Platelet-Rich Plasma
chemical_list: D000418:Albumins; D001798:Blood Proteins; D015718:Fibrin Tissue Adhesive; D005353:Fibronectins; C026912:cryoprecipitate coagulum; D005169:Factor VIII; D005340:Fibrinogen
keywords: albumin; cryoprecipitate; fibrin glue; fibronectin; fresh frozen plasma; ophthalmology; plasmin; platelet rich plasma; serum; whole blood