title: A Review of Membrane-Based Biosensors for Pathogen Detection.
abstract: Biosensors are of increasing interest for the detection of bacterial pathogens in many applications such as human, animal and plant health, as well as food and water safety. Membranes and membrane-like structures have been integral part of several pathogen detection platforms. Such structures may serve as simple mechanical support, function as a part of the transduction mechanism, may be used to filter out or concentrate pathogens, and may be engineered to specifically house active proteins. This review focuses on membrane materials, their associated biosensing applications, chemical linking procedures, and transduction mechanisms. The sensitivity of membrane biosensors is discussed, and the state of the field is evaluated and summarized.
authors.affiliation: Department of Electrical and Computer Engineering, University of Alberta Edmonton, Alberta, AB T6G 2V4, Canada. remko@ualberta.ca.
authors.forename: Remko
authors.initials: R
authors.lastname: van den Hurk
authors.affiliation: Department of Electrical and Computer Engineering, University of Alberta Edmonton, Alberta, AB T6G 2V4, Canada. sevoy@ualberta.ca.
authors.forename: Stephane
authors.initials: S
authors.lastname: Evoy
mesh_terms: D001419:Bacteria / Q000737:chemistry / Q000302:isolation & purification*; D015374:Biosensing Techniques; D003101:Collodion; D008051:Lipid Bilayers; D008567:Membranes, Artificial; D015335:Molecular Probes; D011076:Polycarboxylate Cement; D014780:Viruses / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D008051:Lipid Bilayers; D008567:Membranes, Artificial; D015335:Molecular Probes; D011076:Polycarboxylate Cement; C005506:polycarbonate; D003101:Collodion
keywords: bacteria; biosensors; food safety; membranes; pathogens; water safety