title: Carbon-Carbon Bond Cleavage Reaction: Synthesis of Multisubstituted Pyrazolo[1,5-a]pyrimidines.
abstract: A new carbon-carbon bond cleavage reaction was developed for the efficient synthesis of multisubstituted pyrazolo[1,5-a]pyrimidines. This base induced reaction of 1,3,5-trisubstituted pentane-1,5-diones and substituted pyrazoles afforded good yields of the pyrazolo[1,5-a]pyrimidines.
authors.affiliation: Medicinal Chemistry Division, CSIR-North East Institute of Science and Technology, Jorhat, Assam 785006, India.
authors.forename: Pallabi
authors.initials: P
authors.lastname: Saikia
authors.affiliation: Medicinal Chemistry Division, CSIR-North East Institute of Science and Technology, Jorhat, Assam 785006, India.
authors.forename: Sanjib
authors.initials: S
authors.lastname: Gogoi
authors.affiliation: Medicinal Chemistry Division, CSIR-North East Institute of Science and Technology, Jorhat, Assam 785006, India.
authors.forename: Romesh C
authors.initials: RC
authors.lastname: Boruah
mesh_terms: D002244:Carbon / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D015394:Molecular Structure; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D007659:Ketones; D011720:Pyrazoles; D011743:Pyrimidines; D002244:Carbon