title: Successful treatment of hypertrophic herpes simplex genitalis in HIV-infected patient with topical imiquimod.
abstract: Hypertrophic herpes simplex genitalis is an atypical presentation of genital herpes described in the context of immunosuppression, particularly HIV-positive patients. This situation can become a diagnostic and therapeutic challenge. For this reason, alternative therapies are currently being discussed in the literature. We report a case of hypertrophic genital herpes in a HIV-positive patient who was successfully treated with topical 5% imiquimod after treatment failures with oral and i.v. antivirals.
authors.affiliation: Department of Dermatology, Hospital del Mar, Barcelona, Spain.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Deza
authors.affiliation: Department of Dermatology, Hospital del Mar, Barcelona, Spain.
authors.forename: Gemma
authors.initials: G
authors.lastname: Martin-Ezquerra
authors.affiliation: Department of Dermatology, Hospital del Mar, Barcelona, Spain.
authors.forename: Laia
authors.initials: L
authors.lastname: Curto-Barredo
authors.affiliation: Department of Infectious Diseases, Hospital del Mar, Barcelona, Spain.
authors.forename: Judit
authors.initials: J
authors.lastname: Villar García
authors.affiliation: Department of Dermatology, Hospital del Mar, Barcelona, Spain.
authors.forename: Ramon M
authors.initials: RM
authors.lastname: Pujol
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000287:Administration, Topical; D000634:Aminoquinolines / Q000008:administration & dosage*; D015658:HIV Infections / Q000150:complications*; D006558:Herpes Genitalis / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D006984:Hypertrophy; D000077271:Imiquimod; D008297:Male; D008875:Middle Aged
chemical_list: D000276:Adjuvants, Immunologic; D000634:Aminoquinolines; D000077271:Imiquimod
keywords: HIV infection; genital ulceration; hypertrophic herpes simplex; imiquimod