title: Hybridization chain reaction engineered dsDNA for Cu metallization: an enzyme-free platform for amplified detection of cancer cells and microRNAs.
abstract: A novel enzyme-free platform for amplified detection of cancer cells and miRNAs was constructed with high sensitivity by fluorescent Cu metallization on HCR engineered dsDNA templates.
authors.affiliation: Laboratory of Chemical Biology, State Key laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. jren@ciac.ac.cn xqu@ciac.ac.cn.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.forename: Zhaowei
authors.initials: Z
authors.lastname: Chen
authors.forename: Yu
authors.initials: Y
authors.lastname: Tao
authors.forename: Zhenzhen
authors.initials: Z
authors.lastname: Wang
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D000818:Animals; D052157:Aptamers, Nucleotide / Q000737:chemistry; D003300:Copper / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D056945:Hep G2 Cells; D006801:Humans; D061986:MCF-7 Cells; D051379:Mice; D035683:MicroRNAs / Q000032:analysis*; D041681:NIH 3T3 Cells; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D009369:Neoplasms / Q000175:diagnosis*; D009693:Nucleic Acid Hybridization / Q000379:methods*; D013050:Spectrometry, Fluorescence / Q000379:methods
chemical_list: D052157:Aptamers, Nucleotide; D005456:Fluorescent Dyes; D035683:MicroRNAs; D003300:Copper; D004247:DNA