title: Comparison of clinical outcomes between culprit vessel only and multivessel percutaneous coronary intervention for ST-segment elevation myocardial infarction patients with multivessel coronary diseases.
abstract: BACKGROUND
  The clinical significance of complete revascularization for ST segment elevation myocardial infarction (STEMI) patients during admission is still debatable.
  
  
  METHODS
  A total of 1406 STEMI patients from the Korean Myocardial Infarction Registry with multivessel diseases without cardiogenic shock who underwent primary percutaneous coronary intervention (PPCI) were analyzed. We used propensity score matching (PSM) to control differences of baseline characteristics between culprit only intervention (CP) and multivessel percutaneous coronary interventions (MP), and between double vessel disease (DVD) and triple vessel disease (TVD). The major adverse cardiac event (MACE) was analyzed for one year after discharge.
  
  
  RESULTS
  TVD patients showed higher incidence of MACE (14.2% vs. 8.6%, P = 0.01), any cause of revascularization (10.6% vs. 5.9%, P = 0.01), and repeated PCI (9.5% vs. 5.7%, P = 0.02), as compared to DVD patients during one year after discharge. MP reduced MACE effectively (7.3% vs. 13.8%, P = 0.03), as compared to CP for one year, but all cause of death (1.6% vs. 3.2%, P = 0.38), MI (0.4% vs. 0.8%, P = 1.00), and any cause of revascularization (5.3% vs. 9.7%, P = 0.09) were comparable in the two treatment groups.
  
  
  CONCLUSIONS
  STEMI patients with TVD showed higher rate of MACE, as compared to DVD. MP performed during PPCI or ad hoc during admission for STEMI patients without cardiogenic shock showed lower rate of MACE in this large scaled database. Therefore, MP could be considered as an effective treatment option for STEMI patients without cardiogenic shock.
authors.affiliation: Database and Bioinformatics Laboratory, School of Electrical and Computer Engineering, Chungbuk National University, Cheongju, Chungbuk, South Korea.
authors.forename: Kwang Sun
authors.initials: KS
authors.lastname: Ryu
authors.affiliation: Database and Bioinformatics Laboratory, School of Electrical and Computer Engineering, Chungbuk National University, Cheongju, Chungbuk, South Korea.
authors.forename: Hyun Woo
authors.initials: HW
authors.lastname: Park
authors.affiliation: Database and Bioinformatics Laboratory, School of Electrical and Computer Engineering, Chungbuk National University, Cheongju, Chungbuk, South Korea.
authors.forename: Soo Ho
authors.initials: SH
authors.lastname: Park
authors.affiliation: Database and Bioinformatics Laboratory, School of Electrical and Computer Engineering, Chungbuk National University, Cheongju, Chungbuk, South Korea.
authors.forename: Ho Sun
authors.initials: HS
authors.lastname: Shon
authors.affiliation: Database and Bioinformatics Laboratory, School of Electrical and Computer Engineering, Chungbuk National University, Cheongju, Chungbuk, South Korea.
authors.forename: Keun Ho
authors.initials: KH
authors.lastname: Ryu
authors.affiliation: Human Genome Center, Institute of Medical Science, University of Tokyo, Minatoku, Tokyo, Japan.
authors.forename: Dong Gyu
authors.initials: DG
authors.lastname: Lee
authors.affiliation: Faculty of Computer Science and Information Technology, University of Medical Sciences and Technology, Khartoum, Sudan.
authors.forename: Mohamed Ea
authors.initials: ME
authors.lastname: Bashir
authors.affiliation: Regional Cardiovascular Disease Center, Chungbuk National University Hospital, Cheongju, Chungbuk, South Korea.
authors.forename: Ju Hee
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Regional Cardiovascular Disease Center, Chungbuk National University Hospital, Cheongju, Chungbuk, South Korea.
authors.forename: Sang Min
authors.initials: SM
authors.lastname: Kim
authors.affiliation: Regional Cardiovascular Disease Center, Chungbuk National University Hospital, Cheongju, Chungbuk, South Korea.
authors.forename: Sang Yeub
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Regional Cardiovascular Disease Center, Chungbuk National University Hospital, Cheongju, Chungbuk, South Korea ; Division of Cardiology, Department of Internal Medicine, College of Medicine, Chungbuk National University, Cheongju, Chungbuk, South Korea.
authors.forename: Jang Whan
authors.initials: JW
authors.lastname: Bae
authors.affiliation: Regional Cardiovascular Disease Center, Chungbuk National University Hospital, Cheongju, Chungbuk, South Korea ; Division of Cardiology, Department of Internal Medicine, College of Medicine, Chungbuk National University, Cheongju, Chungbuk, South Korea.
authors.forename: Kyung Kuk
authors.initials: KK
authors.lastname: Hwang
authors.affiliation: Regional Cardiovascular Disease Center, Chungbuk National University Hospital, Cheongju, Chungbuk, South Korea ; Division of Cardiology, Department of Internal Medicine, College of Medicine, Chungbuk National University, Cheongju, Chungbuk, South Korea.
authors.forename: Dong Woon
authors.initials: DW
authors.lastname: Kim
authors.affiliation: Regional Cardiovascular Disease Center, Chungbuk National University Hospital, Cheongju, Chungbuk, South Korea ; Division of Cardiology, Department of Internal Medicine, College of Medicine, Chungbuk National University, Cheongju, Chungbuk, South Korea.
authors.forename: Myeong Chan
authors.initials: MC
authors.lastname: Cho
authors.affiliation: Department of Cardiology, Chonnam National University Hospital, Donggu, Gwangju, South Korea.
authors.forename: Young Keun
authors.initials: YK
authors.lastname: Ahn
authors.affiliation: Department of Cardiology, Chonnam National University Hospital, Donggu, Gwangju, South Korea.
authors.forename: Myung Ho
authors.initials: MH
authors.lastname: Jeong
authors.affiliation: Department of Internal Medicine, Kyunghee University Gangdong Hospital, Seoul, South Korea.
authors.forename: Chong Jin
authors.initials: CJ
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Yeungnam University Hospital, Medical Center, Daegu, South Korea.
authors.forename: Jong Seon
authors.initials: JS
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Yeungnam University Hospital, Medical Center, Daegu, South Korea.
authors.forename: Young Jo
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: Division of Cardiology, Yonsei University, Severance Hospital, Seoul, South Korea.
authors.forename: Yang Soo
authors.initials: YS
authors.lastname: Jang
authors.affiliation: Cardiovascular Center and Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
authors.forename: Hyo Soo
authors.initials: HS
authors.lastname: Kim
authors.affiliation: Department of Cardiovascular Medicine, Catholic University, St. Mary's Hospital, Seoul, South Korea.
authors.forename: Ki Bae
authors.initials: KB
authors.lastname: Seung
keywords: Culprit only intervention; Multivessel coronary disease; Multivessel intervention; Myocardial infarction; Primary percutaneous coronary intervention