title: IQP-VV-102, a Novel Proprietary Composition for Weight Reduction: A Double-Blind Randomized Clinical Trial for Evaluation of Efficacy and Safety.
abstract: The individual ingredients in IQP-VV-102 have demonstrated promising effects in reducing sugar and starch digestion, which potentially leads to weight loss. The trial objective was to evaluate the safety and efficacy of IQP-VV-102 in reducing body weight in overweight and obese subjects. 120 overweight and obese individuals aged 18 to 60 years were randomly assigned to 2 treatment arms (IQP-VV-102 and placebo). The trial was conducted in 2 study centres in Berlin, Germany. The primary efficacy analysis was conducted on 117 subjects (IQP-VV-102: N = 54; placebo: N = 59), comparing the weight loss effect at baseline and 12 weeks after randomization. There was a statistically significant reduction in mean body weight of 3.29 kg (SD 2.30) in the IQP-VV-102 group compared to 0.83 kg (SD 2.00) in the placebo group (p < 0.001). There were no serious or product-related adverse events that were reported over the combined period of 14 weeks. The findings suggested that IQP-VV-102 is effective and safe in body weight reduction in overweight and obese individuals in the short term. The study is registered under clinicaltrials.gov as NCT01681069.
authors.affiliation: Practice for General Medicine, Kurfürstendamm 157/158, 10709 Berlin, Germany.
authors.forename: Barbara
authors.initials: B
authors.lastname: Grube
authors.affiliation: Analyze & Realize GmbH, Weißenseer Weg 111, 10369 Berlin, Germany.
authors.forename: Udo
authors.initials: U
authors.lastname: Bongartz
authors.affiliation: Analyze & Realize GmbH, Waldseeweg 6, 13467 Berlin, Germany.
authors.forename: Felix
authors.initials: F
authors.lastname: Alt