title: Mild and Efficient One-Pot Synthesis of 2-(Perfluoroalkyl)indoles by Means of Sequential Michael-Type Addition and Pd(II)-Catalyzed Cross-Dehydrogenative Coupling (CDC) Reaction.
abstract: 2-Perfluoroalkylated indoles were efficiently synthesized via a one-pot cascade Michael-type addition/palladium-catalyzed intramolecular cross-dehydrogenative coupling (CDC) process, using molecular oxygen as the sole oxidant at 100 °C in DMSO. This process allows atom economical assembly of indole rings from inexpensive and readily available anilines and methyl perfluoroalk-2-ynoates and tolerates a broad range of functional groups.
authors.affiliation: †Department of Chemistry, Innovative Drug Research Center, Shanghai University, Shanghai 200444, People's Republic of China.
authors.forename: Dandan
authors.initials: D
authors.lastname: Shen
authors.affiliation: †Department of Chemistry, Innovative Drug Research Center, Shanghai University, Shanghai 200444, People's Republic of China.
authors.forename: Jing
authors.initials: J
authors.lastname: Han
authors.affiliation: †Department of Chemistry, Innovative Drug Research Center, Shanghai University, Shanghai 200444, People's Republic of China.
authors.forename: Jie
authors.initials: J
authors.lastname: Chen
authors.affiliation: §Laboratory for Microstructures, Instrumental Analysis and Research Center of Shanghai University, Shanghai 200444, People's Republic of China.
authors.forename: Hongmei
authors.initials: H
authors.lastname: Deng
authors.affiliation: §Laboratory for Microstructures, Instrumental Analysis and Research Center of Shanghai University, Shanghai 200444, People's Republic of China.
authors.forename: Min
authors.initials: M
authors.lastname: Shao
authors.affiliation: †Department of Chemistry, Innovative Drug Research Center, Shanghai University, Shanghai 200444, People's Republic of China.|§Laboratory for Microstructures, Instrumental Analysis and Research Center of Shanghai University, Shanghai 200444, People's Republic of China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.affiliation: †Department of Chemistry, Innovative Drug Research Center, Shanghai University, Shanghai 200444, People's Republic of China.|‡State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, People's Republic of China.|∥Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, People's Republic of China.
authors.forename: Weiguo
authors.initials: W
authors.lastname: Cao