title: [The effect of adding phytosterol to hypolipidemic therapy with statins on the size of lipoprotein particles in patients with very high cardiovascular risk].
abstract: Despite significant improvement in the diagnosis and therapy of cardiovascular diseases their global risk and proportion of their clinical forms remains very high. Still the large part of the patients cannot reach the estimated target lipid levels despite statin therapy. Low adherence to preventive programmes with physical training and diet leads to progression of the pathological process of atherothrombosis. One possible therapeutic approach could be the combined hypolipidemic treatment. In this context we followed-up the size of lipoprotein particles among very high risk patients on statin monotherapy, where phytosterole was added. Lipoprotein profile among very high risk patients during combined therapy lead to improvement and therefore may contribute to lowering of their residual risk.
authors.forename: Andrej
authors.initials: A
authors.lastname: Dukát
authors.forename: Ján
authors.initials: J
authors.lastname: Gajdošík
authors.forename: Peter
authors.initials: P
authors.lastname: Sabaka
authors.forename: David
authors.initials: D
authors.lastname: Baláž
authors.forename: Lucia
authors.initials: L
authors.lastname: Mistríková
authors.forename: Stanislav
authors.initials: S
authors.lastname: Oravec
authors.forename: Peter
authors.initials: P
authors.lastname: Gavorník
authors.forename: Ľudovít
authors.initials: Ľ
authors.lastname: Gašpar
mesh_terms: D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control; D004359:Drug Therapy, Combination; D014943:Global Health; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D015994:Incidence; D008074:Lipoproteins / Q000097:blood* / Q000187:drug effects; D010840:Phytosterols / Q000627:therapeutic use*; D012307:Risk Factors
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008074:Lipoproteins; D010840:Phytosterols