title: Quantitative EEG Neurometric Analysis-Guided Neurofeedback Treatment in Dementia: 20 Cases. How Neurometric Analysis Is Important for the Treatment of Dementia and as a Biomarker?
abstract: Dementia is a debilitating degenerative disorder where the sufferer's cognitive abilities decline over time, depending on the type of dementia. The more common types of dementia include Alzheimer's disease and vascular or multi-infarct dementia. In this study, 20 subjects with dementia (9 of Alzheimer's type, and 11 with vascular dementia) were treated using qEEG-guided neurofeedback training. The Mini Mental Status Examination (MMSE) was used as the primary outcome measure. The results showed an increase of the MMSE scores for all subjects regardless of dementia type with an average MMSE score increase of 6 points, which was found to be significant. To our knowledge this is the first time the same modality was shown to be beneficial in both dementia groups.
authors.affiliation: Living Health Center for Research and Education, Sisli, Istanbul, Turkey neuropsychiatry@yahoo.com.
authors.forename: Tanju
authors.initials: T
authors.lastname: Surmeli
authors.affiliation: Brain Power Institute, Sisli, Istanbul, Turkey.
authors.forename: Emin
authors.initials: E
authors.lastname: Eralp
authors.affiliation: Living Health Center for Research and Education, Sisli, Istanbul, Turkey.
authors.forename: Ilhan
authors.initials: I
authors.lastname: Mustafazade
authors.affiliation: Living Health Center for Research and Education, Sisli, Istanbul, Turkey.
authors.forename: Hadi
authors.initials: H
authors.lastname: Kos
authors.affiliation: Brain Power Institute, Sisli, Istanbul, Turkey.
authors.forename: Gül Elif
authors.initials: GE
authors.lastname: Özer
authors.affiliation: Brain Power Institute, Sisli, Istanbul, Turkey.
authors.forename: Orkun H
authors.initials: OH
authors.lastname: Surmeli
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation*; D059445:Anhedonia; D058256:Brain Waves / Q000502:physiology; D002540:Cerebral Cortex / Q000503:physiopathology; D003704:Dementia / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation; D015140:Dementia, Vascular / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation*; D003863:Depression / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D058765:Neurofeedback; D012893:Sleep Wake Disorders / Q000503:physiopathology / Q000523:psychology / Q000534:rehabilitation*
keywords: Alzheimer’s disease; EEG; MMSE; NxLink database; dementia; multi-infarct dementia; neurofeedback; neurometrics; qEEG; vascular dementia