title: Effect of continuous positive airway pressure on proteinuria in obstructive sleep apnea.
abstract: Obstructive sleep apnea (OSA) is common in patients with renal disease, and an association between OSA and proteinuria has been proposed. However, the effect on proteinuria of OSA treatment with continuous positive airway pressure (CPAP) is unknown. We experienced a case of severe OSA, where proteinuria was clearly improved after CPAP initiation without any changes of medication or body weight. The remarkable reduction of repetitive apnea and hypopnea by CPAP might ameliorate proteinuria by lessening renal hypoxia and sympathetic nerve activation. This case suggests that CPAP is a promising option for OSA with proteinuria.
authors.affiliation: Department of Nephrology, Japanese Red Cross Koga Hospital, Koga, Ibaraki, Japan ; Divisionsof Nephrology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Masuda
authors.affiliation: Department of Nephrology, Japanese Red Cross Koga Hospital, Koga, Ibaraki, Japan.
authors.forename: Sumiko
authors.initials: S
authors.lastname: Honma
authors.affiliation: Department of Nephrology, Japanese Red Cross Koga Hospital, Koga, Ibaraki, Japan ; Divisionsof Nephrology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Sasaki
authors.affiliation: Department of Nephrology, Japanese Red Cross Koga Hospital, Koga, Ibaraki, Japan ; Divisionsof Nephrology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
authors.forename: Shiho
authors.initials: S
authors.lastname: Hanawa-Yazawa
authors.affiliation: Divisionsof Nephrology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Iwazu
authors.affiliation: Divisionsof Nephrology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Kusano
authors.affiliation: Department of Nephrology, Japanese Red Cross Koga Hospital, Koga, Ibaraki, Japan.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Asano
keywords: continuous positive airway pressure; obstructive sleep apnea; proteinuria; renal hypoxia