title: Preparation of Porous Chitosan-Siloxane Hybrids Coated with Hydroxyapatite Particles.
abstract: This paper describes the apatite deposition of chitosan-silicate porous hybrids derived from chitosan and γ-glycidoxypropyltrimethoxysilane (GPTMS) in alkaline phosphate solution. The preparation of porous hybrids with needle-like apatite on their surfaces is described. Following apatite deposition the porous hybrids maintained high porosity. The enzymatic degradation rate was low even after 6 months and the porous hybrids were very flexible and cut easily using surgical scissors.
authors.affiliation: Frontier Research Academy for Young Researchers, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu-ku, Kitakyushu 808-0196, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Shirosaki
authors.affiliation: Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors.forename: Kohei
authors.initials: K
authors.lastname: Okamoto
authors.affiliation: Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hayakawa
authors.affiliation: Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan.
authors.forename: Akiyoshi
authors.initials: A
authors.lastname: Osaka
authors.affiliation: Nikkiso Co., Ltd., Ebisu, Shibuya-ku, Tokyo 150-6022, Japan.
authors.forename: Takuji
authors.initials: T
authors.lastname: Asano
mesh_terms: D048271:Chitosan / Q000138:chemical synthesis / Q000737:chemistry*; D017886:Durapatite / Q000138:chemical synthesis / Q000737:chemistry*; D006801:Humans; D016062:Porosity; D017640:Silicates / Q000737:chemistry; D012833:Siloxanes / Q000138:chemical synthesis / Q000737:chemistry*; D054457:Tissue Scaffolds
chemical_list: D017640:Silicates; D012833:Siloxanes; D048271:Chitosan; D017886:Durapatite