title: Effects of music aerobic exercise on depression and brain-derived neurotrophic factor levels in community dwelling women.
abstract: A randomized clinical trial was utilized to compare the improvement of depression and brain-derived neurotrophic factor (BDNF) levels between community women with and without music aerobic exercise (MAE) for 12 weeks. The MAE group involved 47 eligible participants, whereas the comparison group had 59 participants. No significant differences were recorded in the demographic characteristics between the participants in the MAE group and the comparison group. Forty-one participants in the MAE group and 26 in the comparison group completed a pre- and posttest. The MAE group displayed significant improvement in depression scores (p = 0.016), decreased depression symptoms in crying (p = 0.03), appetite (p = 0.006), and fatigue (p = 0.011). The BDNF levels of the participants significantly increased after the 12-week MAE (p = 0.042). The parallel comparison group revealed no significant changes in depression scores or BDNF levels. In summary, the 12-week MAE had a significant impact on the enhancement of BDNF levels and improvement of depression symptoms. Middle-aged community women are encouraged to exercise moderately to improve their depression symptoms and BDNF levels.
authors.affiliation: Department of Medical Research and Development, Show Chwan Memorial Hospital, Changhua 500, Taiwan ; Department of Nursing, Central Taiwan University of Science & Technology, Taichung 400, Taiwan.
authors.forename: Shu-Hui
authors.initials: SH
authors.lastname: Yeh
authors.affiliation: Department of Nursing, Hungkuang University, Taichung 433, Taiwan.
authors.forename: Li-Wei
authors.initials: LW
authors.lastname: Lin
authors.affiliation: Yin Huo Health Association, Kaohsiung 806, Taiwan.
authors.forename: Yu Kuan
authors.initials: YK
authors.lastname: Chuang
authors.affiliation: Department of Medical Research and Development, Show Chwan Memorial Hospital, Changhua 500, Taiwan.
authors.forename: Cheng-Ling
authors.initials: CL
authors.lastname: Liu
authors.affiliation: School of Nursing, National Taichung University of Science & Technology, Taichung 403, Taiwan.
authors.forename: Lu-Jen
authors.initials: LJ
authors.lastname: Tsai
authors.affiliation: Department of Medical Research and Development, Show Chwan Memorial Hospital, Changhua 500, Taiwan.
authors.forename: Feng-Shiou
authors.initials: FS
authors.lastname: Tsuei
authors.affiliation: Department of Medical Research and Development, Show Chwan Memorial Hospital, Changhua 500, Taiwan.
authors.forename: Ming-Tsung
authors.initials: MT
authors.lastname: Lee
authors.affiliation: Department of Nursing, Tzu Hui Institute of Technology, Pingtung County 926, Taiwan.
authors.forename: Chiu-Yueh
authors.initials: CY
authors.lastname: Hsiao
authors.affiliation: Department of Medical Research and Development, Show Chwan Memorial Hospital, Changhua 500, Taiwan ; Institute of Clinical Medicine, National Yang Ming University, Taipei 112, Taiwan.
authors.forename: Kuender D
authors.initials: KD
authors.lastname: Yang
mesh_terms: D000328:Adult; D019208:Brain-Derived Neurotrophic Factor / Q000097:blood*; D003863:Depression / Q000097:blood / Q000523:psychology / Q000628:therapy*; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D057187:Independent Living; D008875:Middle Aged; D009147:Music Therapy / Q000379:methods*
chemical_list: D019208:Brain-Derived Neurotrophic Factor; C579455:BDNF protein, human